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Add v4 regional missense constraint #1662

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Add v4 regional missense constraint #1662

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ad70b64
feat(data-pipeline): add steps for v4 rmc
rileyhgrant Nov 26, 2024
3879ede
feat(graphql-api): update api types
rileyhgrant Nov 26, 2024
7ef6c2e
feat(graphql-api): rig genes indices
rileyhgrant Nov 26, 2024
73071f3
DONTMERGE(graphql-api): dont use gene cache to allow demo
rileyhgrant Nov 26, 2024
acf955e
feat(browser): update rmc with v4
rileyhgrant Nov 26, 2024
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7 changes: 4 additions & 3 deletions browser/src/GenePage/GenePage.tsx
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Original file line number Diff line number Diff line change
Expand Up @@ -22,6 +22,7 @@ import {
isExac,
hasCopyNumberVariants,
isV2,
isV4,
} from '@gnomad/dataset-metadata/metadata'
import ConstraintTable from '../ConstraintTable/ConstraintTable'
import VariantCooccurrenceCountsTable, {
Expand Down Expand Up @@ -134,7 +135,7 @@ export type Gene = GeneMetadata & {
id: string
}[]
exac_regional_missense_constraint_regions?: any
gnomad_v2_regional_missense_constraint?: RegionalMissenseConstraint
gnomad_regional_missense_constraint?: RegionalMissenseConstraint
variants: Variant[]
structural_variants: StructuralVariant[]
copy_number_variants: CopyNumberVariant[]
Expand Down Expand Up @@ -552,9 +553,9 @@ const GenePage = ({ datasetId, gene, geneId }: Props) => {
/>
)}

{isV2(datasetId) && (
{(isV2(datasetId) || isV4(datasetId)) && (
<RegionalMissenseConstraintTrack
regionalMissenseConstraint={gene.gnomad_v2_regional_missense_constraint}
regionalMissenseConstraint={gene.gnomad_regional_missense_constraint}
gene={gene}
/>
)}
Expand Down
2 changes: 1 addition & 1 deletion browser/src/GenePage/GenePageContainer.tsx
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Expand Up @@ -122,7 +122,7 @@ query ${operationName}($geneId: String, $geneSymbol: String, $referenceGenome: R
obs_exp
chisq_diff_null
}
gnomad_v2_regional_missense_constraint {
gnomad_regional_missense_constraint {
passed_qc
has_no_rmc_evidence
regions {
Expand Down
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