Haroon Ahmed PhD 1, Nicola Reeve PhD 1, Ashley Akbari MSc 2, Victoria Best MSc 2, Fatemeh Torabi 2, Rebecca Cannings-John PhD 3, David Gillespie PhD 3, Fiona Lugg-widger PhD 3, Katherine Hughes PhD 4, Mandy Wootton 5
1 Division of Population Medicine, Cardiff University, Cardiff, UK
2 Population Data Science, Swansea University Medical School, Faculty of Medicine, Health & Life Science, Swansea University, Swansea, UK
3 Centre for Trials Research, Cardiff University, Cardiff, UK
4 School of Medicine, Division of Population Medicine, Cardiff, UK
5 Specialist Antimicrobial Chemotherapy Unit, Public Health Wales, Microbiology Cardiff, University Hospital of Wales, Cardiff, UK
Dr Nicola F. Reeve
Division of Population Medicine
Cardiff University
3rd Floor, Neuadd Meirionnydd
Heath Park
Cardiff
CF14 4YS
[email protected]
+44(0)29 20687895
There is increasing interest in the relationship between acute infections and acute cardiovascular events. Most previous research has focused on understanding whether the risk of acute cardiovascular events increases following a respiratory tract infection. The relationship between urinary tract infections (UTIs) and acute cardiovascular events is less well studied. Therefore, the aim of this study is to determine whether there is a causal relationship between UTI and acute myocardial infarction (MI) or stroke.
Reeve NF, Best V, Gillespie D, Hughes K, Lugg-Widger FV, Cannings-John R, Torabi F, Wootton M, Akbari A, Ahmed H. Myocardial infarction and stroke subsequent to urinary tract infection (MISSOURI): protocol for a self-controlled case series using linked electronic health records. BMJ Open. 2022 Sep 22;12(9):e064586. doi: 10.1136/bmjopen-2022-064586. PMID: 36137640; PMCID: PMC9511592.
To be added - not yet published
This work was supported by The British Heart Foundation, grant number PG/20/10419. The Centre for Trials Research is funded by Health and Care Research Wales (grant number N/A) and Cancer Research UK (grant number N/A). Population Data Science, Swansea University is supported by Health Data Research UK (HDR-9006) and ADR Wales (grant ES/S007393/1). PRIME Centre Wales is funded by Health and Care Research Wales.
This study makes use of anonymised data held in the Secure Anonymised Information Linkage (SAIL) Databank. We would like to acknowledge all the data providers who make anonymised data available for research.
All research has been completed under the permission and approval of the SAIL independent Information Governance Review Panel (IGRP) project number 0972. Further details of this process can be found on the SAIL Databank website (https://saildatabank.com/)
Shield:
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is the github repository to store SQL and R scripts and code lists used for the MISSOURI project lead by Haroon Ahmed. SAIL project number 0972