Metabolic capabilities are highly conserved among human nasal-associated Corynebacterium species in pangenomic analyses

Authors: Tommy H. Tran, Isabel F. Escapa, Ari Q. Roberts, Wei Gao, Abiola C. Obawemimo, Julia A. Segre, Heidi H. Kong, Sean Conlan, Matthew S. Kelly, Katherine P. Lemon.

Published in mSystems https://doi.org/10.1128/msystems.01132-24

GitHub Pages Link: https://klemonlab.github.io/CorPGA_Pangenomics/

Input data files provided here.

Supplemental Methods:

• Supplemental methods for program installations.

• Supplemental methods for Prokka annotations of 107 Corynebacterium strain genomes.

• Supplemental methods of pangenome analyses performed with GET_HOMOLOGUES, GET_PHYLOMARKERS and IQ-TREE2.

• Supplemental methods for the anvi'o pangenomic and metabolic analysis.

• Supplemental methods of COG anvi'o annotated gene clusters assignments to the persistent or accessory genome with PPanGGOLiN analysis.

• Supplemental methods for COG functional analysis based on PPanGGOLiN partitions:

  • Corynebacterium propinquum

  • Corynebacterium pseudodiphtheriticum

  • Corynebacterium accolens

  • Corynebacterium tuberculostearicum

• Supplemental methods for the glycogen acumulation analysis.

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