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The latest verion of installation instruction, please! #453

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jielab opened this issue Dec 22, 2024 · 0 comments
Open

The latest verion of installation instruction, please! #453

jielab opened this issue Dec 22, 2024 · 0 comments

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@jielab
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jielab commented Dec 22, 2024

Dear Dr. Zhou:

I am trying to download and install SAIGE.

First, in this Github [https://github.com/weizhouUMICH/SAIGE], it says: Here is a link to download the conda environment file. But over here https://saigegit.**github.io/SAIGE-doc**/, after I run repo_src_url=https://github.com/saigegit/SAIGE;
git clone --depth 1 -b $src_branch $repo_src_url
, I found that the enviromental file inside the "conda_env" folder is different from the previous one. So, can you please let us know which one is the right one to use?

Second, please see the screenshot below. You first showed us to run conda create -n saige and then in Step 1, you showed us to run conda env create -f environment-RSAIGE.yml. So, exactly which command we should run first?
image

Third, I am amzed that a R package could run GWAS for a dataset such as UK Biobank. Now, I have the UKB imputed data in PLINK pgen format, one set of file for each chromosome. Can you please show us an exact pipeline to run SAIGE for a testing trait such as height?

Your help would be greatly appreciated!

Best regards,
Jie

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