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How can I set genotype HOM=0 (no mater it is wild type or mutation) and HET=1? #448

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jeffchen2000 opened this issue Aug 29, 2024 · 0 comments

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@jeffchen2000
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Hi Wei Zhou

how do I treat Genotype in different ways like the plink shown below, basically, I am interested in homozygotes vs. heterozygotes, how can I set genotype HOM=0 (no mater it is wild type or mutation) and HET=1?

thanks
Xianfeng Chen

https://www.cog-genomics.org/plink/1.9/assoc

Additive effect ('ADD')
Dominance deviation ('DOMDEV')
First covariate ('COV1' if not named in the file)
Second covariate
Dosage-first covariate interaction ('ADDxCOV1')
Dominance deviation-first covariate interaction ('DOMDEVxCOV1')
Dosage-second covariate interaction ('ADDxCOV2')
Dominance deviation-second covariate interaction ('DOMDEVxCOV2')

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