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pathway_mapping.yaml
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#pathways:
# - ids:
# - a
# - names:
# - a
go:
- H2O2 : GO:0042542 # response to hydrogen peroxide
- IL-1 : GO:0070498 # interleukin-1-mediated signalling pathway
- JAK-STAT : GO:0007259 # JAK-STAT signal transduction
- MAPK : GO:0000165 # MAPK cascade
- EGFR : GO:0038127 # ERBB signaling pathway
- TLR : GO:0002224 # toll-like receptor signaling pathway
- PI3K : GO:0014065 # phosphatidylinositol 3-kinase signaling
- TGFb : GO:0007179 # transforming growth factor beta receptor signaling pathway
- TNFa : GO:0033209 # tumor necrosis factor-mediated signaling pathway
- VEGF : GO:0038084 # vascular endothelial growth factor signaling pathway
- Wnt : GO:0016055 # Wnt signaling pathway
- Insulin : GO:0008286 # insulin receptor signaling pathway
- Hypoxia : GO:0071456 # cellular response to hypoxia
- RAR : GO:0048384 # retinoic acid receptor signaling pathway
- p53 : GO:0030330 # DNA damage response, signal transduction by p53 class mediator
- Estrogen : GO:0030520 # intracellular estrogen receptor signaling pathway
- Trail : GO:0036462 # TRAIL-activated apoptotic signaling pathway
- notch : GO:0007219 # Notch signaling pathway
- NFkB : GO:0038061 # NIK/NF-kappaB signaling
- PPAR : GO:0035357 # peroxisome proliferator activated receptor signaling pathway
paradigm:
- p53: response to DNA damage stimulus (abstract)
- JAK-STAT: STAT1-3-5-active
- Hypoxia: response to hypoxia (abstract)
- VEGF: platelet-derived growth factor receptor activity (abstract)
- Trail: induction of apoptosis (abstract)
- H2O2: response to hydrogen peroxide (abstract)
- EGFR: epidermal growth factor receptor activity (abstract)
- MAPK: MEK1-2-active
- PI3K: PIK3CA
- TNFa: tumor necrosis factor receptor activity (abstract)
- TGFb: SMAD1-5-8-active
reactome:
- IL-1:
- Interleukin-1 signaling
- JAK-STAT:
- Signaling by Interleukins
- Interferon Signaling
- Signalling to STAT3
- MAPK:
- Signalling to ERKs
- EGFR:
- Signaling by EGFR
- Signaling by EGFR in Cancer
- PI3K:
- PI3K Cascade
- Constitutive Signaling by Aberrant PI3K in Cancer
- PI3K/AKT Signaling in Cancer
- PI3K/AKT activation
- TGFb:
- Signaling by TGF-beta Receptor Complex
- TNFa:
- TNF signaling
- VEGF:
- Signaling by VEGF
- Wnt:
- Signaling by Wnt
- Signaling by WNT in cancer
- Insulin:
- Signaling by Insulin receptor
spia:
- RAR:
- Signaling by Retinoic Acid
- p53:
- Transcriptional Regulation by TP53
- Trail:
- TRAIL signaling
- notch:
- Signaling by NOTCH
- NFkB:
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- RIP-mediated NFkB activation via ZBP1
- PPAR:
- PPARA activates gene expression
- Activation of PPARGC1A (PGC-1alpha) by phosphorylation
- SHH:
- Signaling by Hedgehog
- Hypoxia:
- Cellular response to hypoxia
kegg:
- MAPK: 04010 # MAPK signaling pathway
- EGFR: 04012 # ErbB signaling pathway
- PPAR: 03320 # PPAR signaling pathway
- PI3K: 04150 # mTOR signaling pathway
- Wnt: 04310 # Wnt signaling pathway
- Notch: 04330 # Notch signaling pathway
- Insulin: 04910 # Insulin signaling pathway
- NFkB: 04064 # NF-kappa B signaling pathway
- VEGF: 04370 # VEGF signaling pathway
- JAK-STAT: 04630 # Jak-STAT signaling pathway
- TGFb: 04350 # TGF-beta signaling pathway
- Trail: 04210 # Apoptosis