diff --git a/conda/environments/all_cuda-118_arch-x86_64.yaml b/conda/environments/all_cuda-118_arch-x86_64.yaml
index bf73b938a5..401aa4121c 100644
--- a/conda/environments/all_cuda-118_arch-x86_64.yaml
+++ b/conda/environments/all_cuda-118_arch-x86_64.yaml
@@ -76,7 +76,7 @@ dependencies:
 - sphinx-markdown-tables
 - statsmodels
 - sysroot_linux-64==2.17
-- treelite==4.3.0
+- treelite==4.4.1
 - umap-learn==0.5.6
 - xgboost>=2.1.0
 name: all_cuda-118_arch-x86_64
diff --git a/conda/environments/all_cuda-125_arch-x86_64.yaml b/conda/environments/all_cuda-125_arch-x86_64.yaml
index 72539f2d18..23badefc90 100644
--- a/conda/environments/all_cuda-125_arch-x86_64.yaml
+++ b/conda/environments/all_cuda-125_arch-x86_64.yaml
@@ -72,7 +72,7 @@ dependencies:
 - sphinx-markdown-tables
 - statsmodels
 - sysroot_linux-64==2.17
-- treelite==4.3.0
+- treelite==4.4.1
 - umap-learn==0.5.6
 - xgboost>=2.1.0
 name: all_cuda-125_arch-x86_64
diff --git a/conda/recipes/cuml/conda_build_config.yaml b/conda/recipes/cuml/conda_build_config.yaml
index eb829ba4de..0dde68a976 100644
--- a/conda/recipes/cuml/conda_build_config.yaml
+++ b/conda/recipes/cuml/conda_build_config.yaml
@@ -20,4 +20,4 @@ c_stdlib_version:
   - "=2.17"
 
 treelite_version:
-  - "=4.3.0"
+  - "=4.4.1"
diff --git a/conda/recipes/libcuml/conda_build_config.yaml b/conda/recipes/libcuml/conda_build_config.yaml
index f802440354..5ac453c0ea 100644
--- a/conda/recipes/libcuml/conda_build_config.yaml
+++ b/conda/recipes/libcuml/conda_build_config.yaml
@@ -26,7 +26,7 @@ spdlog_version:
   - ">=1.14.1,<1.15"
 
 treelite_version:
-  - "=4.3.0"
+  - "=4.4.1"
 
 # The CTK libraries below are missing from the conda-forge::cudatoolkit package
 # for CUDA 11. The "*_host_*" version specifiers correspond to `11.8` packages
diff --git a/cpp/cmake/thirdparty/get_treelite.cmake b/cpp/cmake/thirdparty/get_treelite.cmake
index a14bacb531..9a221f1b85 100644
--- a/cpp/cmake/thirdparty/get_treelite.cmake
+++ b/cpp/cmake/thirdparty/get_treelite.cmake
@@ -1,5 +1,5 @@
 #=============================================================================
-# Copyright (c) 2021-2024, NVIDIA CORPORATION.
+# Copyright (c) 2021-2025, NVIDIA CORPORATION.
 #
 # Licensed under the Apache License, Version 2.0 (the "License");
 # you may not use this file except in compliance with the License.
@@ -78,7 +78,7 @@ function(find_and_configure_treelite)
     rapids_export_find_package_root(BUILD Treelite [=[${CMAKE_CURRENT_LIST_DIR}]=] EXPORT_SET cuml-exports)
 endfunction()
 
-find_and_configure_treelite(VERSION     4.3.0
-                        PINNED_TAG  575e4208f2b18e40d818c338ecb95d7a26e69aab
+find_and_configure_treelite(VERSION     4.4.1
+                        PINNED_TAG  386bd0de99f5a66584c7e58221ee38ce606ad1ae
                         EXCLUDE_FROM_ALL  ${CUML_EXCLUDE_TREELITE_FROM_ALL}
                         BUILD_STATIC_LIBS ${CUML_USE_TREELITE_STATIC})
diff --git a/dependencies.yaml b/dependencies.yaml
index 90e6dc5fc2..91e7d0623d 100644
--- a/dependencies.yaml
+++ b/dependencies.yaml
@@ -215,7 +215,7 @@ dependencies:
       - output_types: [conda, requirements, pyproject]
         packages:
           - &cython cython>=3.0.0
-          - &treelite treelite==4.3.0
+          - &treelite treelite==4.4.1
     specific:
       - output_types: [conda, requirements, pyproject]
         matrices:
diff --git a/python/cuml/pyproject.toml b/python/cuml/pyproject.toml
index 2f0521fe6e..95885de503 100644
--- a/python/cuml/pyproject.toml
+++ b/python/cuml/pyproject.toml
@@ -109,7 +109,7 @@ dependencies = [
     "rapids-dask-dependency==25.2.*,>=0.0.0a0",
     "rmm==25.2.*,>=0.0.0a0",
     "scipy>=1.8.0",
-    "treelite==4.3.0",
+    "treelite==4.4.1",
 ] # This list was generated by `rapids-dependency-file-generator`. To make changes, edit ../../dependencies.yaml and run `rapids-dependency-file-generator`.
 classifiers = [
     "Intended Audience :: Developers",
@@ -181,7 +181,7 @@ requires = [
     "ninja",
     "pylibraft==25.2.*,>=0.0.0a0",
     "rmm==25.2.*,>=0.0.0a0",
-    "treelite==4.3.0",
+    "treelite==4.4.1",
 ] # This list was generated by `rapids-dependency-file-generator`. To make changes, edit ../../dependencies.yaml and run `rapids-dependency-file-generator`.
 
 [tool.scikit-build]