diff --git a/requirements/base.txt b/requirements/base.txt
index c158e77dc..73b8e93fb 100644
--- a/requirements/base.txt
+++ b/requirements/base.txt
@@ -78,7 +78,7 @@ sphinxext-rediraffe==0.2.7
     # via -r requirements/base.in
 typing-extensions==4.8.0
     # via pydata-sphinx-theme
-urllib3==2.0.7
+urllib3==2.1.0
     # via requests
 zipp==3.17.0
     # via importlib-metadata
diff --git a/requirements/common_constraints.txt b/requirements/common_constraints.txt
index afe6aa887..15aafb293 100644
--- a/requirements/common_constraints.txt
+++ b/requirements/common_constraints.txt
@@ -21,7 +21,3 @@ elasticsearch<7.14.0
 
 # django-simple-history>3.0.0 adds indexing and causes a lot of migrations to be affected
 django-simple-history==3.0.0
-
-# tox>4.0.0 isn't yet compatible with many tox plugins, causing CI failures in almost all repos.
-# Details can be found in this discussion: https://github.com/tox-dev/tox/discussions/1810
-tox<4.0.0
diff --git a/requirements/dev.txt b/requirements/dev.txt
index 69ca9f8c8..aedbc666f 100644
--- a/requirements/dev.txt
+++ b/requirements/dev.txt
@@ -137,7 +137,7 @@ typing-extensions==4.8.0
     # via
     #   -r requirements/base.txt
     #   pydata-sphinx-theme
-urllib3==2.0.7
+urllib3==2.1.0
     # via
     #   -r requirements/base.txt
     #   requests