Multi-objective Approach for ROI study of Schizophrenia using fMRI data.

[Remi-Gau]

Region(s) of Interest (ROI) - based analysis to inspect functional changes in predefined region(s) in schizophrenic brain. Schizophrenia affects different regions of the brain which subsequently causes hallucination and delusion. Localization of affected regions in schizophrenia may help us understand the condition and effect of disorder better and may also assist in deciding the line of treatment. This project will throw some light on the region-wise analysis and their individual working condition in the brain having schizophrenia.

Objective of the Project:

1. ROI study of affected brain in schizophrenia using fMRI data to investigate the functional changes in each region.
2. Identification of the most affected region(s) in Schizophrenia
3. To develop a decision model using Multi-objective optimisation evolutionary approach.

We will be using some pre-defined atlases on FBIRN Phase II Data repository. With due acknowledgment, I have attached the PreProcessed(Direct Normalisation upto smoothing) Auditory Oddball task dataset for 4 runs of 1.5T fMRI dataset of 34 schizophrenic and 34 healthy subjects. Also attached the Contrast Maps for each run of the data after applying GLM approach.
Repository with data and atlas can be found here: https://github.com/IndraChatterjee/fMRI-ROI-analysis-of-Schizophrenia