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CHANGELOG.md

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CHANGELOG

v1.0c

  • multithreading via Process with Queue
  • support for encrypted models
  • support for new GPUs (pytorch v2.1.2 / cuda v12.1)
  • removed b100_RNA002

v1.0b

  • tRNA support via alignment-based segmentation
  • new demux models:
    • mRNA: b96_RNA002 and b100_RNA002
      • deprecated b12_RNA002
    • tRNA: b04_RNA002_tRNA
  • added bam_split_by_barcode.py that splits BAM files by barcode
  • removed multithreading support: it's not memory-safe for pod5 files that may have millions of entries

v1.0a3

  • pod5 support
  • fast5_split_by_barcode.py added

v1.0a2

  • fixed several critical issues
  • demux models: b12_RNA002

v1.0a

  • mRNA support via signal-based segmentation using T-test with two rolling windows
  • Fast5 support
  • demux models: b04_RNA002 and b04_RNA004