From 96863f267a9a9ddf9c934cc480ac31fd492c573b Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 28 Aug 2024 18:02:27 +0200 Subject: [PATCH 01/53] removing creation of bindingsite matrix in majority vote --- modules/local/majority_vote/main.nf | 7 ++++--- 1 file changed, 4 insertions(+), 3 deletions(-) diff --git a/modules/local/majority_vote/main.nf b/modules/local/majority_vote/main.nf index 33f417ba..c77ecb0f 100644 --- a/modules/local/majority_vote/main.nf +++ b/modules/local/majority_vote/main.nf @@ -11,9 +11,10 @@ process MAJORITY_VOTE { tuple val(meta), path(bindingsites) output: - tuple val(meta), path("${meta.id}.majority.tsv"), emit: tsv - tuple val(meta), path("${meta.id}.targets.tsv") , emit: targets - path "versions.yml" , emit: versions + tuple val(meta), path("${meta.id}.majority.tsv") , emit: tsv + tuple val(meta), path("${meta.id}.targets.tsv") , emit: targets + tuple val(meta), path("${meta.id}.binding_sites.tsv") , emit: binding_sites + path "versions.yml" , emit: versions when: task.ext.when == null || task.ext.when From a82d1f934a0b060cc76330f00a08f5f217b7dd0a Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 28 Aug 2024 18:02:56 +0200 Subject: [PATCH 02/53] adding sponge for testing --- modules/local/sponge/main.nf | 44 +++++ modules/local/sponge/templates/sponge.R | 212 ++++++++++++++++++++++++ 2 files changed, 256 insertions(+) create mode 100644 modules/local/sponge/main.nf create mode 100644 modules/local/sponge/templates/sponge.R diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/main.nf new file mode 100644 index 00000000..1c56e457 --- /dev/null +++ b/modules/local/sponge/main.nf @@ -0,0 +1,44 @@ +process SPONGE { + tag "$meta.id" + label 'process_high' + + conda "${moduleDir}/environment.yml" + container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? + 'oras://community.wave.seqera.io/library/bioconductor-deseq2_bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:379bbce95f2c4913' : + 'community.wave.seqera.io/library/bioconductor-deseq2_bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:f38bbe7441604bcc' }" + + input: + tuple val(meta), path(binding_sites) + tuple val(meta), path(gene_expr) + tuple val(meta), path(mirna_expr) + + + output: + path "versions.yml" , emit: versions + path "sponge.RData" , emit: sponge_data + path "circRNAs_as_ceRNAs.tsv" , emit: cernas + path "total_plots.pdf" , emit: total_plots + path "simulation_plots.pdf" , emit: simulation_plots + path "circRNA_plots.pdf" , emit: circ_plots + + + when: + task.ext.when == null || task.ext.when + + script: + template 'sponge.R' + + stub: + """ + touch "sponge.RData" + + cat <<-END_VERSIONS > versions.yml + "${task.process}": + bioconductor-deseq2: \$(Rscript -e "library(DESeq2); cat(as.character(packageVersion('DESeq2')))") + bioconductor-sponge: \$(Rscript -e "library(SPONGE); cat(as.character(packageVersion('SPONGE')))") + r-visnetwork: \$(Rscript -e "library(visNetwork); cat(as.character(packageVersion('visNetwork')))") + r-doparallel: \$(Rscript -e "library(doParallel); cat(as.character(packageVersion('doParallel')))") + r-foreach: \$(Rscript -e "library(foreach); cat(as.character(packageVersion('foreach')))") + END_VERSIONS + """ +} diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/templates/sponge.R new file mode 100644 index 00000000..59ca8600 --- /dev/null +++ b/modules/local/sponge/templates/sponge.R @@ -0,0 +1,212 @@ +#!/usr/bin/env Rscript + +library(SPONGE) +library(visNetwork) +library(doParallel) +library(foreach) +library(DESeq2) + +circ_mRNA_subnetwork <- function(interactions, pattern) { + return(interactions[ + (grepl(pattern, interactions\$geneA) & !grepl(pattern, interactions\$geneB)) | + (grepl(pattern, interactions\$geneB) & !grepl(pattern, interactions\$geneA)), + ]) +} + +normalize_data <- function(data){ + samples <- colnames(data) + meta <- data.frame(row.names = samples) + data <- as.matrix(data) + dds <- DESeq2::DESeqDataSetFromMatrix(countData = round(data + 1), colData = meta, design = ~ 1) + dds <- DESeq2::estimateSizeFactors(dds) + return(DESeq2::counts(dds, normalized=TRUE)) +} + +# load binding sites matrix +bindingsites <- read.table("${binding_sites}", sep = "\\t", header = TRUE, check.names = FALSE) +rownames(bindingsites) <- bindingsites[, 1] +bindingsites <- bindingsites[, -1] +bindingsites_matrix <- as.matrix(bindingsites) + + +# load gene expression +genes <- read.csv("${gene_expr}", sep = "\\t", row.names = "tx") +genes <- subset(genes, select = -gene_id) +# prep for DESeq2 +gene_expr <- normalize_data(as.matrix(genes)) +gene_expr <- t(as.matrix(genes)) + + +# load mirna expression +mirna <- read.csv("${mirna_expr}", sep = "\\t", row.names = "miRNA") +mirna[is.na(mirna)] <- 0 +mir_expr <- t(as.matrix(mirna)) + + +# ensure that both matrices have the same samples +common_samples <- intersect(rownames(gene_expr), rownames(mir_expr)) + +# subset and reorder the rows (samples) of both matrices to match each other (as specified in SPONGE docs) +gene_expr <- gene_expr[common_samples, ] +mir_expr <- mir_expr[common_samples, ] + + +###################################### +# A # +###################################### +logging.file <- "sponge.log" +# number of cores from args +cores <- ${params.sponge_cpus} + +cl <- makeCluster(cores, outfile=logging.file) +registerDoParallel(cl) + +gene_expriRNA_candidates <- SPONGE::sponge_gene_miRNA_interaction_filter( + gene_expr = gene_expr, + mir_expr = mir_expr, + mir_predicted_targets = bindingsites_matrix, + F.test = FALSE, + coefficient.threshold = -0.01, + coefficient.direction = NULL +) + + + # F.test.p.adj.threshold = ${params.sponge_f_test_pval}, + # coefficient.threshold = ${params.sponge_coeff_threshold}, + # elastic.net = ("${params.sponge_elastic_net}" == "true") + +###################################### +# B # +###################################### +ceRNA_interactions <- SPONGE::sponge( + gene_expr = gene_expr, + mir_expr = mir_expr, + mir_interactions = gene_expriRNA_candidates +) + + +###################################### +# C # +###################################### + +mscor_null_model <- SPONGE::sponge_build_null_model( + number_of_datasets = 100, + number_of_samples = nrow(gene_expr) +) + +sim_plot <- SPONGE::sponge_plot_simulation_results(mscor_null_model) +pdf("simulation_plots.pdf") +plot(sim_plot) +dev.off() + +ceRNA_interactions_sign <- SPONGE::sponge_compute_p_values( + sponge_result = ceRNA_interactions, + null_model = mscor_null_model +) + +###################################### +# D # +###################################### +ceRNA_interactions_fdr <- ceRNA_interactions_sign[which(ceRNA_interactions_sign\$p.adj < ${params.sponge_fdr}), ] +min.interactions <- 5000 + +if (nrow(ceRNA_interactions_fdr) < min.interactions && nrow(ceRNA_interactions_sign) > min.interactions) { + print("Warning: fdr setting too strict, no significant interactions detected; min of padj is:") + print(min(ceRNA_interactions_sign\$p.adj)) + print("adjusting...") + fdr <- min(ceRNA_interactions_sign\$p.adj) * 1.01 + ceRNA_interactions_fdr <- ceRNA_interactions_sign[which(ceRNA_interactions_sign\$p.adj < fdr), ] + while(nrow(ceRNA_interactions_fdr) < min.interactions) { + fdr <- fdr * 1.01 + ceRNA_interactions_fdr <- ceRNA_interactions_sign[which(ceRNA_interactions_sign\$p.adj < fdr), ] + } + cat("adjusted fdr to :", fdr, "to allow for a minimum", min.interactions, "interactions", "\\n") + cat("current fdr relevant interactions:", nrow(ceRNA_interactions_fdr)) + ceRNA_interactions_fdr <- ceRNA_interactions_fdr[order(ceRNA_interactions_fdr\$p.adj), ] +} + +# MOST SIGNIFICANT SPONGES +network_centralities <- SPONGE::sponge_node_centralities(ceRNA_interactions_fdr) +ceRNA_interactions_weight <- ceRNA_interactions_fdr +ceRNA_interactions_weight\$weight <- -log10(ceRNA_interactions_fdr\$p.adj) +weighted_network_centralities <- SPONGE::sponge_node_centralities(ceRNA_interactions_weight) +weighed_network_plot <- SPONGE::sponge_plot_network_centralities(weighted_network_centralities, top = 3) +pdf("total_plots.pdf") +plot(weighed_network_plot) +dev.off() + +# CIRC RNA MRNA ONLY +circ_mRNA_only <- circ_mRNA_subnetwork(ceRNA_interactions_fdr, "circ") +write.table(circ_mRNA_only, "circRNAs_as_ceRNAs.tsv", sep = "\\t", row.names = FALSE) + +# TODO: REMOVE +write.table(ceRNA_interactions, "ceRNAs_interactions.tsv", sep = "\\t", row.names = FALSE) + +# NETWORK ANALYSIS CIRC +ceRNA_interactions_circ_weight <- circ_mRNA_only +ceRNA_interactions_circ_weight\$weight <- -log10(circ_mRNA_only\$p.val) +weighted_network_centralities_circ <- SPONGE::sponge_node_centralities(ceRNA_interactions_circ_weight) + +# plot top n samples +n = 10 # TODO: param + +# betweeness +top_network_plot_btw <- SPONGE::sponge_plot_network_centralities( + weighted_network_centralities_circ, + top = n, + measure = "btw" +) + +# eigenvector +top_network_plot_ev <- SPONGE::sponge_plot_network_centralities( + weighted_network_centralities_circ, + top = n, + measure = "ev" +) + +# counts +top_network_plot_c <- SPONGE::sponge_plot_network_centralities( + weighted_network_centralities_circ, + top = n, + measure = "count" +) + +pdf("circRNA_plots.pdf") +plot(top_network_plot_btw) +plot(top_network_plot_ev) +plot(top_network_plot_c) +dev.off() +stopCluster(cl) + +# save R objects for sponge effects +save.image(file = "sponge.RData") + +################################################ +################################################ +## VERSIONS FILE ## +################################################ +################################################ + +deseq2.version <- as.character(packageVersion('DESeq2')) +sponge.version <- as.character(packageVersion('SPONGE')) +visnetwork.version <- as.character(packageVersion('visNetwork')) +doparallel.version <- as.character(packageVersion('doParallel')) +foreach.version <- as.character(packageVersion('foreach')) + +writeLines( + c( + '"${task.process}":', + paste(' bioconductor-deseq2:', deseq2.version), + paste(' bioconductor-sponge:', sponge.version), + paste(' r-visnetwork:', visnetwork.version), + paste(' r-doparallel:', doparallel.version), + paste(' r-foreach:', foreach.version) + ), +'versions.yml') + + +################################################ +################################################ +################################################ +################################################ +################################################ From 0548d99a5f094be9ab5e9c2f82e233cce5362f70 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 28 Aug 2024 18:03:55 +0200 Subject: [PATCH 03/53] changing process label for circ annotate to medium --- modules/nf-core/circexplorer2/annotate/main.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/nf-core/circexplorer2/annotate/main.nf b/modules/nf-core/circexplorer2/annotate/main.nf index 0e9fa0a0..8374a835 100644 --- a/modules/nf-core/circexplorer2/annotate/main.nf +++ b/modules/nf-core/circexplorer2/annotate/main.nf @@ -1,6 +1,6 @@ process CIRCEXPLORER2_ANNOTATE { tag "$meta.id" - label 'process_low' + label 'process_medium' conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? From 6fb5a6eebad625678e14a076878ee357f45c7b0e Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 28 Aug 2024 18:04:25 +0200 Subject: [PATCH 04/53] passing transcript counts through pipeline to sponge --- subworkflows/local/mirna/mirna_bindingsites.nf | 3 ++- subworkflows/local/mirna_prediction.nf | 12 ++++++++---- workflows/circrna/main.nf | 2 +- 3 files changed, 11 insertions(+), 6 deletions(-) diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index f6633ee5..e03bf0b7 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -79,7 +79,8 @@ workflow MIRNA_BINDINGSITES { ch_versions = ch_versions.mix(MAJORITY_VOTE.out.versions) emit: - binding_sites = MAJORITY_VOTE.out.targets + targets = MAJORITY_VOTE.out.targets + binding_sites = MAJORITY_VOTE.out.binding_sites versions = ch_versions } diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index b3fc46cc..dfa2c224 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -3,6 +3,7 @@ include { BIOAWK as ADD_BACKSPLICE } from '../../modules/nf-core/bioawk' include { DESEQ2_NORMALIZATION } from '../../modules/local/deseq2/normalization' include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' +include { SPONGE } from '../../modules/local/sponge' // SUBWORKFLOWS include { MIRNA_BINDINGSITES } from './mirna/mirna_bindingsites' @@ -14,8 +15,8 @@ workflow MIRNA_PREDICTION { circrna_annotation ch_mature ch_mirna - transcript_counts quantification_rds + tx_counts main: ch_versions = Channel.empty() @@ -26,7 +27,7 @@ workflow MIRNA_PREDICTION { if (params.mirna_expression) { - ch_mirna_normalized = DESEQ2_NORMALIZATION( ch_mirna ).normalized + ch_mirna_normalized = DESEQ2_NORMALIZATION(ch_mirna).normalized ch_versions = ch_versions.mix(DESEQ2_NORMALIZATION.out.versions) @@ -59,14 +60,14 @@ workflow MIRNA_PREDICTION { .map{ it -> [[id: 'mature_filtered'], it]} } - MIRNA_BINDINGSITES( transcriptome_fasta, circrna_annotation, ch_mature ) + MIRNA_BINDINGSITES(transcriptome_fasta, circrna_annotation, ch_mature) ch_versions = ch_versions.mix(MIRNA_BINDINGSITES.out.versions) if (params.mirna_expression) { // // COMPUTE CORRELATION: // - ch_binding_site_batches = MIRNA_BINDINGSITES.out.binding_sites + ch_binding_site_batches = MIRNA_BINDINGSITES.out.targets .splitText(by: 100, file: true) .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} @@ -80,6 +81,9 @@ workflow MIRNA_PREDICTION { ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) } + // if (params.sponge) + SPONGE(MIRNA_BINDINGSITES.out.binding_sites, tx_counts, ch_mirna_filtered) + emit: versions = ch_versions } diff --git a/workflows/circrna/main.nf b/workflows/circrna/main.nf index 435fc0b2..0da695ff 100644 --- a/workflows/circrna/main.nf +++ b/workflows/circrna/main.nf @@ -176,7 +176,7 @@ workflow CIRCRNA { BSJ_DETECTION.out.bed12, ch_mature, ch_mirna, - QUANTIFICATION.out.circ, + QUANTIFICATION.out.tx_counts, QUANTIFICATION.out.rds ) ch_versions = ch_versions.mix(MIRNA_PREDICTION.out.versions) From 24f139b11f9d006c0b90b98d4eeb01821b040664 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 28 Aug 2024 18:04:32 +0200 Subject: [PATCH 05/53] adding sponge params --- nextflow.config | 17 +++++++++ nextflow_schema.json | 84 +++++++++++++++++++++++++++++++++++++++++++- 2 files changed, 100 insertions(+), 1 deletion(-) diff --git a/nextflow.config b/nextflow.config index e74c8867..10235132 100644 --- a/nextflow.config +++ b/nextflow.config @@ -78,6 +78,23 @@ params { //> MISC save_unaligned = false seq_center = null + + // MIRNA options + + //> MIRNA processing + mirna_expression = null + mirna_min_reads = 5 + mirna_min_sample_percentage = 0.2 + mirna_tools = 'miranda,targetscan' + mirna_tool_filter = 1 + mirna_correlation = 'pearson' + + //> SPONGE + sponge_fdr = 0.01 + sponge_cpus = 12 + sponge_f_test_pval = 0.05 + sponge_coeff_threshold = -0.05 + sponge_elastic_net = true // MultiQC options skip_fastqc = false diff --git a/nextflow_schema.json b/nextflow_schema.json index 6250658f..93a30639 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -163,7 +163,7 @@ "description": "Minimum number of reads, a miRNA is required to have to pass filtering.", "help_text": "This parameter determines the minimum number of reads that a miRNA must have to pass filtering. The default is 5, meaning a miRNA must have at least 5 reads across the samples to be considered for analysis.", "default": 5, - "minimum": 0 + "minimum": 1 }, "mirna_correlation": { "type": "string", @@ -173,6 +173,88 @@ "default": "pearson", "pattern": "^(pearson|spearman)$" }, + "sponge_fdr": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "", + "help_text": "FDR rate for ceRNA networks.", + "default": 0.01 + }, + "sponge_cpus": { + "type": "integer", + "fa_icon": "fas fa-circle-notch", + "description": "", + "help_text": "Number of cores to use for parallelization.", + "default": 12 + }, + "sponge_f_test_pval": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "If F.test is TRUE, threshold to use for miRNAs to be included.", + "help_text": "Option to filter with different f test p values.", + "default": 0.05 + }, + "sponge_coeff_threshold": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Threshold to cross for a regression coefficient to be called significant.", + "help_text": "Option to filter with different coefficient thresholds.", + "default": -0.05, + "minimum": -1 + }, + "sponge_elastic_net": { + "type": "boolean", + "fa_icon": "fas fa-circle-notch", + "description": "Determins whether to apply elastic net regression filtering or not.", + "help_text": "Option to filter with elastic net.", + "default": true + } + } + }, + "discovery_options": { + "title": "Discovery Options", + "type": "object", + "fa_icon": "fas fa-circle-notch", + "description": "Parameters for circrna discovery.", + "required": ["tools"], + "properties": { + "tools": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "Comma separated list of circRNA quantification tools to use. Supported tools: ciriquant, circexplorer2, find_circ, circrna_finder, mapsplice, dcc, segemehl", + "pattern": "^(ciriquant|circexplorer2|find_circ|circrna_finder|mapsplice|dcc|segemehl)(,(ciriquant|circexplorer2|find_circ|circrna_finder|mapsplice|dcc|segemehl))*$", + "help_text": "Select one or a combination of circRNA quantification tools for the pipeline e.g:\n--tool 'circexplorer2, ciriquant, find_circ'\n\nN.B: Selecting more than one circRNA quantification tool will trigger the circRNA filtering parameter --tool_filter", + "default": "circexplorer2" + }, + "bsj_reads": { + "type": "integer", + "fa_icon": "fas fa-circle-notch", + "description": "Minimum number of reads spanning circRNA back-splice junction required for circRNA to be output by workflow.", + "help_text": "Filter low confidence circRNAs by removing circRNAs with read counts below a specified value. To disable, set the value to 1 (default).", + "default": 1, + "minimum": 1 + }, + "tool_filter": { + "type": "integer", + "fa_icon": "fas fa-intersection", + "description": "Specify the minimum number of tools circRNAs must be called by to be output by the workflow.", + "help_text": "When multiple circRNA quantification tools have been provided to `--tool`, set a filtering method whereby circRNAs are output if they have been called by at least *n* quantification tools.\n\nSetting `--tool_filter` to 1 is the same as taking the union, all circRNAs are included in the output.\n\nSetting `--tool_filter` to 2 will output circRNAs that have been called by at least 2 quantification tools and so on.", + "default": 1, + "minimum": 1, + "maximum": 7 + }, + "save_intermediates": { + "type": "boolean", + "description": "Save intermediate alignment/circRNA files.", + "default": false, + "fa_icon": "fas fa-save" + }, + "exon_boundary": { + "type": "integer", + "description": "Specify the distance at which the annotation script decides if a candidate is a circRNA or EI-circRNA.", + "help_text": "During annotation, if one of the start or end position of a circular candidate imperfectly overlaps an exon boundary, the script will consider positions within 'exon_boundary' (default 0bp) to be an exonic circRNA. If they fall outside of this range, the candidate is assumed to be an exonic-intronic circRNA, and the entire underlying sequence is taken for miRNA analysis, as opposed to just the exonic sequences for canonical exonic circRNAs. ", + "default": 0 + }, "mirna_tools": { "type": "string", "fa_icon": "fas fa-wrench", From e987ac11041b18efb4ff79668ce6f883117cf2f0 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 5 Sep 2024 18:12:25 +0200 Subject: [PATCH 06/53] adjusting output to match spongeEffects input --- modules/local/sponge/main.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/main.nf index 1c56e457..4edaccb0 100644 --- a/modules/local/sponge/main.nf +++ b/modules/local/sponge/main.nf @@ -15,7 +15,7 @@ process SPONGE { output: path "versions.yml" , emit: versions - path "sponge.RData" , emit: sponge_data + tuple val(meta), path("sponge.RData") , emit: sponge_data path "circRNAs_as_ceRNAs.tsv" , emit: cernas path "total_plots.pdf" , emit: total_plots path "simulation_plots.pdf" , emit: simulation_plots From 77b52dc4ecda04aa849b2158c67c31d033ae5545 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 5 Sep 2024 18:12:58 +0200 Subject: [PATCH 07/53] adding sponge effects for testing --- modules/local/sponge_effects/main.nf | 41 ++ .../sponge_effects/templates/sponge_effects.R | 696 ++++++++++++++++++ nextflow.config | 12 + nextflow_schema.json | 83 +++ subworkflows/local/mirna_prediction.nf | 4 + 5 files changed, 836 insertions(+) create mode 100644 modules/local/sponge_effects/main.nf create mode 100644 modules/local/sponge_effects/templates/sponge_effects.R diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge_effects/main.nf new file mode 100644 index 00000000..6c24c7ae --- /dev/null +++ b/modules/local/sponge_effects/main.nf @@ -0,0 +1,41 @@ +process SPONGE_EFFECTS { + tag "$meta.id" + label 'process_high' + + conda "${moduleDir}/environment.yml" + container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? + 'oras://community.wave.seqera.io/library/bioconductor-rtracklayer_bioconductor-sponge_r-base_r-doparallel_pruned:16ef0e7778b29e70' : + 'community.wave.seqera.io/library/bioconductor-rtracklayer_bioconductor-sponge_r-base_r-doparallel_pruned:74e394923e2c369a' }" + + input: + tuple val(meta), path(sponge_data) + + output: + // TODO + + + when: + task.ext.when == null || task.ext.when + + script: + template 'sponge_effects.R' + + stub: + """ + touch "test.txt" + + cat <<-END_VERSIONS > versions.yml + "${task.process}": + bioconductor-rtracklayer: \$(Rscript -e "library(foreach); cat(as.character(packageVersion('foreach')))") + bioconductor-sponge: \$(Rscript -e "library(SPONGE); cat(as.character(packageVersion('SPONGE')))") + r-doparallel: \$(Rscript -e "library(doParallel); cat(as.character(packageVersion('doParallel')))") + r-dplyr: \$(Rscript -e "library(dplyr); cat(as.character(packageVersion('dplyr')))") + r-foreach: \$(Rscript -e "library(foreach); cat(as.character(packageVersion('foreach')))") + r-ggplot2: \$(Rscript -e "library(ggplot2); cat(as.character(packageVersion('ggplot2')))") + r-ggpubr: \$(Rscript -e "library(ggpubr); cat(as.character(packageVersion('ggpubr')))") + r-pheatmap: \$(Rscript -e "library(pheatmap); cat(as.character(packageVersion('pheatmap')))") + r-reshape2: \$(Rscript -e "library(reshape2); cat(as.character(packageVersion('reshape2')))") + r-visnetwork: \$(Rscript -e "library(visNetwork); cat(as.character(packageVersion('visNetwork')))") + END_VERSIONS + """ +} diff --git a/modules/local/sponge_effects/templates/sponge_effects.R b/modules/local/sponge_effects/templates/sponge_effects.R new file mode 100644 index 00000000..78ccf733 --- /dev/null +++ b/modules/local/sponge_effects/templates/sponge_effects.R @@ -0,0 +1,696 @@ +#!/usr/bin/env Rscript + +if(!require(pacman)) install.packages("pacman", repos = "http://cran.us.r-project.org") +pacman::p_load(SPONGE, doParallel, foreach, dplyr, visNetwork, pheatmap, ggplot2, reshape2, ggpubr, rtracklayer) + +######################## +## GENERAL FUNCTIONS ### +######################## +# plot ceRNA network with gene annotations +plot_network <- function(ceRNA_network, signif_hits = NULL, + gtf = NULL, annotation = NULL) { + # plot network + ceRNA_plot <- sponge_plot_network(ceRNA_network, genes_miRNA_candidates, ) %>% + visNetwork::visEdges(arrows = list(to = list(enabled = TRUE, scaleFactor = 1))) + + ceRNA_plot\$x\$edges\$label <- paste("mscor:", round(ceRNA_network\$mscor, 2)) + + # extract nodes and edges for customization + nodes <- ceRNA_plot\$x\$nodes + edges <- ceRNA_plot\$x\$edges + + # mark differentially expressed RNAs + if (!is.null(signif_hits)){ + nodes[nodes\$id %in% hgncs\$hgnc_symbol | nodes\$id %in% signif_hits\$X,"group"] <- "DE" + } + if (!is.null(gtf)) { + gtf <- rtracklayer::readGFF(gtf) + annotation <- unique(gtf[!is.na(gtf\$transcript_id),c("gene_id", "gene_name", "gene_type")]) + colnames(annotation) <- c("ensembl_gene_id", "hgnc_symbol", "gene_type") + rownames(annotation) <- annotation\$ensembl_gene_id + } + if (!is.null(annotation)){ + # break types of RNA down to lncRNA, coding, and rest + annotation\$gene_type[annotation\$gene_type != "protein_coding" & annotation\$gene_type != "lncRNA"] <- "other_RNA" + + nodes <- merge(nodes, annotation, by = 1, all.x = TRUE) + + # change to hgnc + nodes[!is.na(nodes\$hgnc_symbol), 1:2] <- nodes[!is.na(nodes\$hgnc_symbol), "hgnc_symbol"] + + # add circRNA as gene_type + nodes[is.na(nodes\$gene_type) & !grepl("ENSG", nodes\$id), "gene_type"] <- "circRNA" + # label unknown RNAs as other + nodes[is.na(nodes\$gene_type), "gene_type"] <- "other_RNA" + # remove preset color and shape + nodes <- nodes[, -c(3,4)] + # change to group + colnames(nodes)[8] <- "group" + + # convert geneA and geneB + edges <- merge(edges, annotation, by.x = "from", by.y = 1, all.x = TRUE) + edges[!is.na(edges\$hgnc_symbol), "from"] <- edges\$hgnc_symbol[!is.na(edges\$hgnc_symbol)] + edges <- merge(edges, annotation, by.x = "to", by.y = 1, all.x = TRUE) + edges[!is.na(edges\$hgnc_symbol.y), "to"] <- edges\$hgnc_symbol.y[!is.na(edges\$hgnc_symbol.y)] + } + # plot final graph + graph <- visNetwork(nodes = nodes, edges = edges) %>% + visIgraphLayout(type = "full", physics = FALSE) %>% + visGroups(groupname = "circRNA", shape = "rectangle", color = "#33FF99") %>% + visGroups(groupname = "protein_coding", shape = "triangle", color = "#0066CC") %>% + visGroups(groupname = "lncRNA", shape = "square", color = "#F8766D") %>% + visGroups(groupname = "other_RNA", color = "#DC71FA", shape = "diamond") %>% + visGroups(groupname = "DE", color = "#CC3333") %>% + visLegend() + return(graph) +} + + +circ.mRNA.subnetwork <- function(interactions, pattern){ + return(interactions[ + (grepl(pattern, interactions\$geneA) & !grepl(pattern, interactions\$geneB)) | + (grepl(pattern, interactions\$geneB) & !grepl(pattern, interactions\$geneA)), + ]) +} + +# plot model performance (spongEffects) +plot_performance <- function (trained_model, central_genes_model = NULL, + random_model, training_dataset_name = "TCGA", + testing_dataset_name = "TCGA", subtypes){ + trained.model <- trained_model + CentralGenes.model <- central_genes_model + Random.model <- random_model + training_string <- paste0(training_dataset_name, " (Training)") + testing_string <- paste0(testing_dataset_name, " (Testing)") + set_names <- c(training_string, testing_string) + SpongingActiivty.model <- trained_model + + if (!is.null(central_genes_model)) { + Accuracy.df <- data.frame( + Run = rep(set_names, 3), + Model = c(rep("Modules", 2), rep("Central Genes", 2), rep("Random", 2)), + Accuracy = c( + SpongingActiivty.model\$ConfusionMatrix_training[["overall"]][["Accuracy"]], + SpongingActiivty.model\$ConfusionMatrix_testing[["overall"]][["Accuracy"]], + CentralGenes.model\$ConfusionMatrix_training[["overall"]][["Accuracy"]], + CentralGenes.model\$ConfusionMatrix_testing[["overall"]][["Accuracy"]], + Random.model\$ConfusionMatrix_training[["overall"]][["Accuracy"]], + Random.model\$ConfusionMatrix_testing[["overall"]][["Accuracy"]] + ) + ) + Accuracy.df\$Model <- factor(Accuracy.df\$Model, levels = c("Modules", "Random", "Central Genes")) + Accuracy.df\$Run <- factor(Accuracy.df\$Run, levels = set_names) + } + else { + Accuracy.df <- data.frame( + Run = rep(set_names, 2), + Model = c(rep("Modules", 2), + rep("Random", 2)), + Accuracy = c( + SpongingActiivty.model\$ConfusionMatrix_training[["overall"]][["Accuracy"]], + SpongingActiivty.model\$ConfusionMatrix_testing[["overall"]][["Accuracy"]], + Random.model\$ConfusionMatrix_training[["overall"]][["Accuracy"]], + Random.model\$ConfusionMatrix_testing[["overall"]][["Accuracy"]] + ) + ) + Accuracy.df\$Model <- factor(Accuracy.df\$Model, levels = c("Modules", "Random")) + Accuracy.df\$Run <- factor(Accuracy.df\$Run, levels = set_names) + } + Accuracy.plot <- Accuracy.df %>% ggplot(aes(x = Accuracy, y = Model)) + + geom_line(aes(group = Model)) + + geom_point(aes(shape = Run)) + + theme_light() + + xlab("Subset Accuracy") + + ylab("") + + theme_bw() + Metrics.SpongeModules.training <- SpongingActiivty.model\$ConfusionMatrix_training\$byClass[,"Balanced Accuracy"] %>% + as.data.frame() %>% mutate(Model = "Modules") %>% tibble::rownames_to_column("Class") + colnames(Metrics.SpongeModules.training) = c("Class", "Value", "Model") + Metrics.Random.training <- Random.model\$ConfusionMatrix_training\$byClass[, "Balanced Accuracy"] %>% + as.data.frame() %>% mutate(Model = "Random") %>% tibble::rownames_to_column("Class") + colnames(Metrics.Random.training) = c("Class", "Value", "Model") + if (!is.null(central_genes_model)) { + Metrics.CentralGenes.training <- CentralGenes.model\$ConfusionMatrix_training[["byClass"]][c(1:length(unique(subtypes)))] %>% + as.data.frame() %>% mutate(Model = "Central Genes") %>% + tibble::rownames_to_column("Class") + colnames(Metrics.CentralGenes.training) = c("Class", "Value", "Model") + Metrics.training <- rbind( Metrics.SpongeModules.training, rbind( Metrics.Random.training, Metrics.CentralGenes.training)) %>% mutate(Run = training_string) + } + else { + Metrics.training <- rbind(Metrics.SpongeModules.training, Metrics.Random.training) %>% mutate(Run = training_string) + } + Metrics.SpongeModules.testing <- SpongingActiivty.model\$ConfusionMatrix_testing\$byClass[, "Balanced Accuracy"] %>% + as.data.frame() %>% mutate(Model = "Modules") %>% tibble::rownames_to_column("Class") + colnames(Metrics.SpongeModules.testing) = c("Class", "Value", "Model") + Metrics.Random.testing <- Random.model\$ConfusionMatrix_testing\$byClass[, "Balanced Accuracy"] %>% + as.data.frame() %>% mutate(Model = "Random") %>% tibble::rownames_to_column("Class") + colnames(Metrics.Random.testing) = c("Class", "Value", "Model") + if (!is.null(central_genes_model)) { + Metrics.CentralGenes.testing <- CentralGenes.model\$ConfusionMatrix_testing[["byClass"]][c(1:length(unique(subtypes)))] %>% + as.data.frame() %>% mutate(Model = "Central Genes") %>% tibble::rownames_to_column("Class") + colnames(Metrics.CentralGenes.testing) = c("Class", "Value", "Model") + Metrics.testing <- rbind(Metrics.SpongeModules.testing, rbind(Metrics.Random.testing, Metrics.CentralGenes.testing)) %>% + mutate(Run = testing_string) + } + else { + Metrics.testing <- rbind(Metrics.SpongeModules.testing, Metrics.Random.testing) %>% mutate(Run = testing_string) + } + Metrics <- rbind(Metrics.training, Metrics.testing) + if (!is.null(central_genes_model)) { + Metrics\$Model <- factor(Metrics\$Model, levels = c("Modules", "Random", "Central Genes")) + } + else { + Metrics\$Model <- factor(Metrics\$Model, levels = c("Modules", "Random")) + } + Metrics\$Run <- factor(Metrics\$Run, levels = set_names) + Metrics\$Class <- gsub("Class: ", "", Metrics\$Class) + Metrics.plot <- Metrics %>% ggplot(aes(x = Class, y = Value, fill = Model)) + + geom_bar(position = "dodge", stat = "identity", width = 0.5) + + facet_grid(Metrics\$Run) + + xlab("Accuracy") + + ylab("") + theme_bw() + metric_plots <- ggarrange(Accuracy.plot, Metrics.plot, ncol = 1, nrow = 2) + return(metric_plots) +} + +# plot lollipop (spongEffects) +plot_modules <- function (trained_model, + k_modules = 25, + k_modules_red = 10, + text_size = 16){ + final.model <- trained_model\$Model\$finalModel + Variable.importance <- importance(final.model) %>% as.data.frame() %>% + tibble::rownames_to_column("Module") %>% arrange(desc(MeanDecreaseGini)) + grey_modules = k_modules - k_modules_red + p <- Variable.importance[1:k_modules, ] %>% + mutate(Analysed = c(rep("1", k_modules_red), rep("0", grey_modules))) %>% + arrange(desc(MeanDecreaseGini)) %>% + ggplot(aes(x = reorder(Module, MeanDecreaseGini), y = MeanDecreaseGini)) + + geom_point() + + geom_segment(aes(x = Module, xend = Module, y = 0, yend = MeanDecreaseGini, color = Analysed)) + + scale_colour_manual(values = c("red", "black"), breaks = c("1", "0")) + + coord_flip() + + xlab("Module") + + ylab("Mean decrease in Gini index") + + theme_light() + + theme(panel.grid.major.x = element_blank(), + panel.grid.minor.x = element_blank(), axis.ticks.y = element_blank(), + legend.title = element_blank(), legend.position = "none", + legend.background = element_blank(), legend.direction = "horizontal", + panel.border = element_rect(colour = "black", fill = NA, size = 1), text = element_text(size = 16)) + return(p) +} + +# Training heat map (spongEffects) +plot_hmap <- function (trained_model, + spongEffects, + meta_data, + label, + sampleIDs, + Modules_to_Plot = 5, + show.rownames = F, + show.colnames = F){ + if (label %in% colnames(meta_data) & sampleIDs %in% colnames(meta_data)) { + final.model <- trained_model\$Model\$finalModel + Variable.importance <- importance(final.model) %>% as.data.frame() %>% + tibble::rownames_to_column("Module") %>% arrange(desc(MeanDecreaseGini)) + Variable.importance\$Module <- gsub("`", "", Variable.importance\$Module) + Annotation.meta <- meta_data[match(colnames(spongEffects), meta_data[, sampleIDs]), ] + unique_subtypes <- unique(Annotation.meta\$label) + number_groups <- length(unique_subtypes) + col.heatmap <- met.brewer("Renoir", n = number_groups, type = "continuous") + col.heatmap <- as.vector(col.heatmap) + col.heatmap <- setNames(col.heatmap, unique_subtypes) + col.heatmap <- cell.colors + Column.Annotation <- HeatmapAnnotation(Group = Annotation.meta[, label], col = list(Group = col.heatmap)) + spongeEffects.toPlot <- spongEffects[match(Variable.importance\$Module, rownames(spongEffects)), ] + spongeEffects.toPlot <- spongeEffects.toPlot[rowSums(is.na(spongeEffects.toPlot)) == 0, ] + if (Modules_to_Plot > length(rownames(spongeEffects.toPlot))) + Modules_to_Plot = length(rownames(spongeEffects.toPlot)) + spongeEffects.toPlot <- spongeEffects.toPlot[1:Modules_to_Plot, ] + Heatmap.p <- spongeEffects.toPlot %>% t() %>% scale() %>% + t() %>% Heatmap(show_row_names = show.rownames, + show_column_names = show.colnames, + top_annotation = Column.Annotation, + show_heatmap_legend = TRUE) + return(Heatmap.p) + } + else { + print("label and/or sampleIDs must be columns in metadata") + } +} + +# Target gene heat map (spongEffects) +plot_target_gene_expressions <- function(target, target_genes, + gene_expression, meta, + log_transform = TRUE, + pseudocount = 1, gtf_raw = NULL, + annotation = NULL, + split = "condition", unit = "counts", + show_rows = TRUE, + annotation_colors = NULL){ + # get target expression + target_expression <- gene_expression[ ,target, drop = FALSE] + # get target genes expressions + target_genes_expression <- gene_expression[ ,target_genes] + # combine into one + data <- t(cbind(target_expression, target_genes_expression)) + # save all conditions of samples + conditions <- unique(meta[,split]) + + # convert to hgnc if gtf is given + if (!is.null(gtf_raw)) { + print("reading GTF file and converting to HGNC symbols...") + gtf <- rtracklayer::readGFF(gtf) + gene.ens.all <- unique(gtf[!is.na(gtf\$transcript_id), c("gene_id", "gene_name")]) + colnames(gene.ens.all) <- c("ensembl_gene_id", "hgnc_symbol") + rownames(gene.ens.all) <- gene.ens.all\$ensembl_gene_id + # convert + annotation = gene.ens.all + } + if (!is.null(annotation)){ + ensgs <- rownames(data) + ensgs <- merge(ensgs, annotation, by = 1, all.x = TRUE) + ensgs[!is.na(ensgs\$hgnc_symbol),"x"] <- ensgs[!is.na(ensgs\$hgnc_symbol), "hgnc_symbol"] + rownames(data) <- ensgs\$x + } + # heat color scheme + colors <- c(colorRampPalette(c("blue", "orange"))(100), colorRampPalette(c("orange", "red"))(100)) + # annotation colors are given + if (!is.null(annotation_colors)) { + annotation.colors <- annotation_colors + } else { + annotation.colors <- hcl.colors(length(conditions), palette = hcl.pals(type = "diverging")[12]) + } + # name colors + names(annotation.colors) <- conditions + a_c <- list(x = annotation.colors) + names(a_c) <- split + + if (log_transform) { + data = log2(data + pseudocount) + } + colnames(data) <- gsub("\\\\.", "-", colnames(data)) + label <- paste0("Module ", unit, " expression for: ", target) + # create annotation for heat map + df <- data.frame(meta[,c("sample", split)], row.names = 1) + pheatmap::pheatmap(data, treeheight_row = 0, treeheight_col = 0, + show_colnames = FALSE, show_rownames = show_rows, + cluster_rows = TRUE, cluster_cols = TRUE, + color = colors, annotation_col = df, + annotation_colors = a_c, + main = label, fontsize_row = 10) +} + +# plot expression of miRNAs in module for specific RNA (no negative values!) +plot_miRNAs_per_gene <- function(target, genes_miRNA_candidates, + mir_expr, meta, + log_transform = TRUE, pseudocount = 1e-3, + unit = "counts", split = "condition", + annotation_colors = NULL){ + # extract miRNAs associated with given RNA + candidates <- genes_miRNA_candidates[[target]] + miRNAs <- candidates[["mirna"]] + miRNA_expr <- mir_expr[ ,miRNAs] + + # sum all expressions for the given conditions + miRNA_expr <- merge(miRNA_expr, meta[ ,c("sample", split)], by.x = 0, by.y = "sample") + miRNA_expr <- data.frame(miRNA_expr, row.names = 1, check.names = FALSE) + miRNA_expr <- aggregate(miRNA_expr[ ,1:(ncol(miRNA_expr)-1)], list(condition = miRNA_expr[ ,split]), FUN=sum) + miRNA_expr <- t(data.frame(miRNA_expr, row.names = 1)) + miRNA_expr <- melt(miRNA_expr, id.vars = "x", varnames = c("miRNA", "variable")) + miRNA_expr\$miRNA <- gsub("\\\\.", "-", miRNA_expr\$miRNA) + + # label + label <- paste0("miRNA ", unit, " over samples") + # log transform if given + if (log_transform){ + miRNA_expr\$value <- log10(miRNA_expr\$value + pseudocount) + label <- paste0("log10 + ", pseudocount, " ", label) + } + # annotation colors are given + if (!is.null(annotation_colors)) { + annotation.colors <- annotation_colors + } else { + annotation.colors <- hcl.colors(length(conditions), palette = hcl.pals(type = "diverging")[12]) + } + # name colors + names(annotation.colors) <- conditions + # two bar plots in one + bars <- ggplot(miRNA_expr, aes(y=miRNA, x=value, fill=variable)) + + ggtitle(target) + + geom_bar(stat='identity', position='dodge') + + xlab(label) + + scale_fill_manual(values = annotation.colors, name = "Condition") + return(bars) +} + +#---------------------------OUTPUT DIR-------------------------------- +ROOT = "." +# create plot directory +PLOT_DIR = file.path(ROOT, "plots") +dir.create(PLOT_DIR, recursive = TRUE, showWarnings = FALSE) +#---------------------------SPONGE DATA------------------------------- +print("loading SPONGE data...") +load("${sponge_data}") # input from pipeline + +#---------------------------GTF DATA---------------------------------- +gtf <- rtracklayer::readGFF("${params.gtf}") +gene.ens.all <- unique(gtf[!is.na(gtf\$transcript_id),c("gene_id", "transcript_id", "gene_name")]) +print("loaded gtf") +colnames(gene.ens.all) <- c("ensembl_gene_id", "hgnc_symbol", "gene_type") +rownames(gene.ens.all) <- gene.ens.all\$hgnc_symbol + +#---------------------------PARAMETERS-------------------------------- +mscor.threshold = 0.001 # "${params.sponge_ef_mscor}" +padj.threshold = 0.7 # "${params.sponge_ef_fdr}" +modules_cutoff = "${params.sponge_ef_enrichment_modules}" +bin.size = "${params.sponge_ef_enrichment_bins}" +min.size = "${params.sponge_ef_enrichment_min}" +max.size = "${params.sponge_ef_enrichment_max}" +min.expr = "${params.sponge_ef_enrichment_expr}" +method = "${params.sponge_ef_enrichment_method}" +split_training = "${params.sponge_ef_training}" +folds = "${params.sponge_ef_folds}" + +#---------------------------PARALLEL BACKGROUND----------------------- +num.of.cores <- 8 +cl <- makeCluster(num.of.cores) +registerDoParallel(cl) + +#---------------------------META FILE/ CONDITIONS--------------------- +meta <- read.csv(file = "${params.input}") + +#---------------------------EXTENDING META---------------------------- +phenotype <- read.csv("${params.phenotype}") +meta <- merge(meta, phenotype, by = "sample") + + +# ----------------EXPRESSION SPLITTING-------------------------------- +n.train <- round(nrow(meta)*split_training) +n.test <- round(nrow(meta)-n.train) + +# randomize samples +meta <- meta[sample(1:nrow(meta)), ] +# take n samples from each group +cond.split <- split(meta, meta\$condition) +cond.ratio <- round(sapply(cond.split, function(x) nrow(x) * split_training)) +train.meta <- data.table::rbindlist(mapply(function(x,y) x[1:y,], cond.split, cond.ratio, SIMPLIFY = FALSE)) +colnames(train.meta) <- c("sampleIDs", c(colnames(train.meta)[3:length(train.meta) - 1], "label")) +test.meta <- data.table::rbindlist(mapply(function(x,y) x[(y + 1):nrow(x), ], cond.split, cond.ratio, SIMPLIFY = FALSE)) +colnames(test.meta) <- c("sampleIDs", c(colnames(test.meta)[3:length(test.meta)], "label")) + +rownames(gene_expr) <- gsub("\\\\.", "-", rownames(gene_expr)) # MALTE TODO: check if this translates to \\ in work dir +# train gene expression; split_training of samples +train_gene_expr <- gene_expr[rownames(gene_expr) %in% train.meta\$sampleIDs, ] +train_gene_expr <- t(train_gene_expr) +# test gene expression; rest of samples +test_gene_expr <- gene_expr[rownames(gene_expr) %in% test.meta\$sampleIDs, ] +test_gene_expr <- t(test_gene_expr) + +# train miRNA expression +train_mirna_expr <- mir_expr[rownames(mir_expr) %in% train.meta\$sampleIDs, ] +# test miRNA expression +test_mirna_expr <- mir_expr[rownames(mir_expr) %in% test.meta\$sampleIDs, ] + +#-------------------------CE RNA SPLITTING------------------------ +# MALTE TODO: no circ interactions -> empty df +# MALTE TODO: hard code path for now in template +ceRNA_interactions_sign <- read.table("/nfs/home/students/mweyrich/sponge/ceRNA_interactions_sign.tsv", header = TRUE, check.names = FALSE) + +ceRNA_interactions_fdr <- ceRNA_interactions_sign[which(ceRNA_interactions_sign\$p.adj < padj.threshold), ] +ceRNA_interactions_fdr <- circ.mRNA.subnetwork(ceRNA_interactions_fdr, "circ") + +n.train.ce <- round(nrow(ceRNA_interactions_fdr) * split_training) +n.test.ce <- nrow(ceRNA_interactions_fdr) - n.train.ce +train_ceRNA_interactions <- head(ceRNA_interactions_fdr, n.train.ce) +test_ceRNA_interactions <- tail(ceRNA_interactions_fdr, n.test.ce) +#-------------------------CENTRALITIES SPLITTING------------------ +network_centralities <- sponge_node_centralities(ceRNA_interactions_fdr) +n.train.c <- round(nrow(network_centralities) * split_training) +n.test.c <- nrow(network_centralities) - n.train.c +train_network_centralities <- head(network_centralities, n.train.c) +test_network_centralities <- tail(network_centralities, n.test.c) + +#-------------------------FILTERING------------------------------- +print("filtering centralities...") + +filtered_network_centralities <- filter_ceRNA_network(sponge_effects = train_ceRNA_interactions, + Node_Centrality = train_network_centralities, + add_weighted_centrality = TRUE, + mscor.threshold = mscor.threshold, + padj.threshold = padj.threshold) +#-------------------------RNAS_OF_INTEREST------------------------ +RNAs <- c("lncRNA", "circRNA") +# ensembl.df is part of SPONGE lib +RNAs.ofInterest <- ensembl.df %>% dplyr::filter(gene_biotype %in% RNAs) %>% + dplyr::select(ensembl_gene_id) +# add circRNAs of the data set +new_circRNAs <- data.frame(ensembl_gene_id = colnames(gene_expr)[grep("c", colnames(gene_expr))]) +RNAs.ofInterest <- rbind(RNAs.ofInterest, new_circRNAs) +# get central modules +central_gene_modules <- get_central_modules(central_nodes = RNAs.ofInterest\$ensembl_gene_id, + node_centrality = filtered_network_centralities\$Node_Centrality, + ceRNA_class = RNAs, + centrality_measure = "Weighted_Degree", + cutoff = modules_cutoff) +#-------------------------SPONGE MODULES--------------------------- +Sponge.modules <- define_modules(network = filtered_network_centralities\$Sponge.filtered, + central.modules = central_gene_modules, + remove.central = FALSE, + set.parallel = FALSE) +# Module size distribution +Size.modules <- sapply(Sponge.modules, length) +#-------------------------SPLIT MODULES---------------------------- +# train and test modules +train.modules <- enrichment_modules(Expr.matrix = train_gene_expr, + modules = Sponge.modules, + bin.size = bin.size, + min.size = min.size, + max.size = max.size, + min.expr = min.expr, + method = method) + +test.modules <- enrichment_modules(Expr.matrix = test_gene_expr, + modules = Sponge.modules, + bin.size = bin.size, + min.size = min.size, + max.size = max.size, + min.expr = min.expr, + method = method) + +#-------------------------MODEL PERFORMANCE-------------------------- +common_modules = intersect(rownames(train.modules), rownames(test.modules)) +train.modules = train.modules[common_modules, ] +test.modules = test.modules[common_modules, ] +trained.model = calibrate_model(Input = train.modules, + modules_metadata = train.meta, + label = "label", + sampleIDs = "sampleIDs", + Metric = "Exact_match", + n_folds = folds, + repetitions = 3) +trained.model[["ConfusionMatrix_training"]] + +Input.test <- t(test.modules) %>% scale(center = TRUE, scale = TRUE) +Prediction.model <- predict(trained.model\$Model, Input.test) +# We compute the confusion metrix on the test set +ConfusionMatrix_testing <- caret::confusionMatrix(as.factor(Prediction.model), as.factor(test.meta\$label)) +trained.model\$ConfusionMatrix_testing <- ConfusionMatrix_testing + +#-------------------------RANDOM MODULES---------------------------- +Random.modules <- Random_spongEffects(sponge_modules = Sponge.modules, + gene_expr = train_gene_expr, + min.size = min.size, + bin.size = bin.size, + max.size = max.size, + min.expression=min.expr, + replace = FALSE, + method = method) + +# We can now use the randomly defined modules to calculate their enrichment in the test set +Random.modules.test <- enrichment_modules(Expr.matrix = test_gene_expr, + modules = Random.modules\$Random_Modules, + bin.size = bin.size, + min.size = min.size, + max.size = max.size, + min.expr = min.expr, + method = method) + +# We find random modules that were identified both in the train and test and use those as input features for the model +common_modules_random = intersect(rownames(Random.modules\$Enrichment_Random_Modules), rownames(Random.modules.test)) +Random.modules.train = Random.modules\$Enrichment_Random_Modules[common_modules_random, ] +Random.modules.test = Random.modules.test[common_modules_random, ] +Random.model = calibrate_model(Input = Random.modules.train, + modules_metadata = train.meta, + label = "label", sampleIDs = "sampleIDs", + Metric = "Exact_match", + n_folds = folds, repetitions = 1) +Random.model[["ConfusionMatrix_training"]] + +# validate on test set +Input.test <- t(Random.modules.test) %>% scale(center = TRUE, scale = TRUE) +Input.test<-Input.test[ , apply(Input.test, 2, function(x) !any(is.na(x)))] +Prediction.model <- predict(Random.model\$Model, Input.test) +# We compute the confusion metrix on the test set +ConfusionMatrix_testing_random <- caret::confusionMatrix(as.factor(Prediction.model), as.factor(test.meta\$label)) +Random.model\$ConfusionMatrix_testing_random <- ConfusionMatrix_testing_random +ConfusionMatrix_testing_random + +#-------------------------PLOT PERFOMANCES------------------------- +train_name <- paste0(split_training * 100, "%") # MALTE TODO: maybe also escape +test_name <- paste0((1-split_training) * 100, "%") +metrics_plot <- plot_performance(trained_model = trained.model, + random_model = Random.model, + central_genes_model = NULL, + training_dataset_name = train_name, + testing_dataset_name = test_name, + subtypes = as.factor(train.meta\$label)) +# save metrics plot +ggsave(file.path(PLOT_DIR, "metrics.png"), metrics_plot, + width = 7.25, height = 5.25, dpi = 1200) + +#-------------------------PLOT CLASS DISTRIBUTION------------------ +density_plot_train <- plot_density_scores(trained_model = trained.model, + spongEffects = train.modules, + meta_data = train.meta, + label = "label", + sampleIDs = "sampleIDs") +# save class plot +ggsave(file.path(PLOT_DIR, "classification.png"), density_plot_train, + width = 12, height = 8, dpi = 300) + +#-------------------------PLOT TOP RESULTS------------------------- +lollipop_plot <- plot_modules(trained_model = trained.model, k_modules_red = 2, + k_modules = 7, text_size = 20) +# save lollipop plot +ggsave(file.path(PLOT_DIR, "lollipop.png"), lollipop_plot, + width = 7.25, height = 5.25, dpi = 1200) + +#-------------------------PLOT NETWORK FOR CENTRALITIES------------ +n = 25 +central_players <- central_gene_modules %>% + arrange(desc(Weighted_Degree)) %>% + dplyr::select(gene) %>% slice_head(n = n) %>% unlist +# filter network for central players, filter for circRNA-mRNA connections +network <- circ.mRNA.subnetwork(filtered_network_centralities\$Sponge.filtered, "circ") +subnetwork <- network %>% + dplyr::filter(geneA %in% central_players | geneB %in% central_players) +network_plot <- plot_network(subnetwork, + annotation = gene.ens.all, + node_label_size = 40, edge_label_size = 0) +# save network +visNetwork::visSave(network_plot, file = file.path(PLOT_DIR, paste0("top_", n, "_ceRNA_centralities.html"))) + +#-------------------------EXTRACT TOP circRNAs--------------------- +Variable.importance <- importance(trained.model\$Model\$finalModel) %>% as.data.frame() %>% + tibble::rownames_to_column("Module") %>% arrange(desc(MeanDecreaseGini)) +k = 6 +candidates <- Variable.importance[1:k, "Module"] +candidates <- gsub("`", "", candidates) +# candidate modules +candidate.modules <- Sponge.modules[candidates] +# continue with top 2 (highest gini indices) +sponged.genes <- candidate.modules[candidates] + +#-------------------------PLOT TOP circRNA modules----------------- +top_network_plot <- plot_network(ceRNA_network = network %>% + dplyr::filter(geneA %in% candidates | geneB %in% candidates), + annotation = gene.ens.all, + node_label_size = 40, edge_label_size = 0) +# plot top k centralities network +visNetwork::visSave(top_network_plot, + file = file.path(PLOT_DIR, paste0("top_", k, "_ceRNA_centralities.html"))) + +#-------------------------MODULE EXPRESSION------------------------ +# generate module expression for each candidate +candidate_plots <- list() +for (candidate in candidates) { + module <- candidate.modules[candidate][[1]] + module <- module[!grepl("c", module)] + module_gene_plot <- plot_target_gene_expressions(candidate, module, + gene_expression = gene_expr, + meta = meta, + annotation = gene.ens.all, + unit = "counts", + log_transform = TRUE, + show_rows = FALSE) + module_miRNA_plot <- plot_miRNAs_per_gene(candidate, + genes_miRNA_interactions_manual, + mir_expr = mir_expr, meta = meta, + log_transform = TRUE) + candidate_plots[[candidate]] <- ggarrange(module_gene_plot, module_miRNA_plot, + ncol = 2, nrow = 1) +} +# arrange candidate plots +candidate_plots_arranged <- ggarrange(plotlist = candidate_plots, + ncol = 1, nrow = k) +# save candidate heat maps +ggsave(file.path(PLOT_DIR, "candidates_hms.png"), candidate_plots_arranged, + width = 5.25, height = 10.25, dpi = 1200) + +#-------------------------spongEffects HMAP------------------------ +train.hmap <- plot_hmap(trained_model = trained.model, + spongEffects = train.modules, + meta_data = train.meta, + label = "label", sampleIDs = "sampleIDs", + Modules_to_Plot = 2, + show.rownames = TRUE, + show.colnames = FALSE) +test.hmap <- plot_hmap(trained_model = trained.model, + spongEffects = test.modules, + meta_data = test.meta, + label = "label", + sampleIDs = "sampleIDs", + Modules_to_Plot = 2, + show.rownames = TRUE, + show.colnames = FALSE) +# save train and test heat maps +ggsave(file.path(PLOT_DIR, "train_hm.png"), train.hmap, + width = 7.25, height = 5.25, dpi = 1200) +ggsave(file.path(PLOT_DIR, "test_hm.png"), test.hmap, + width = 7.25, height = 5.25, dpi = 1200) + +#-------------------------SAVE R-SESSION---------------------------- +save.image(file.path(ROOT, "spongEffects.RData")) + + +################################################ +################################################ +## VERSIONS FILE ## +################################################ +################################################ + +r.version <- strsplit(version[['version.string']], ' ')[[1]][3] +rtracklayer.version <- as.character(packageVersion('rtracklayer')) +sponge.version <- as.character(packageVersion('SPONGE')) +doparallel.version <- as.character(packageVersion('doParallel')) +dplyr.version <- as.character(packageVersion('dplyr')) +foreach.version <- as.character(packageVersion('foreach')) +ggplot2.version <- as.character(packageVersion('ggplot2')) +ggpubr.version <- as.character(packageVersion('ggpubr')) +pheatmap.version <- as.character(packageVersion('pheatmap')) +reshape2.version <- as.character(packageVersion('reshape2')) +visnetwork.version <- as.character(packageVersion('visNetwork')) + +writeLines( + c( + '"${task.process}":', + paste(' r-base:', r.version) + paste(' bioconductor-rtracklayer', rtracklayer.version) + paste(' bioconductor-sponge', sponge.version) + paste(' r-doparallel', doparallel.version) + paste(' r-dplyr', dplyr.version) + paste(' r-foreach', foreach.version) + paste(' r-ggplot2', ggplot2.version) + paste(' r-ggpubr', ggpubr.version) + paste(' r-pheatmap', pheatmap.version) + paste(' r-reshape2', reshape2.version) + paste(' r-visnetwork', visnetwork.version) + ), +'versions.yml') + +################################################ +################################################ +################################################ +################################################ diff --git a/nextflow.config b/nextflow.config index 10235132..827a58f8 100644 --- a/nextflow.config +++ b/nextflow.config @@ -96,6 +96,18 @@ params { sponge_coeff_threshold = -0.05 sponge_elastic_net = true + //> SPONGE_Effects + sponge_ef_training = 0.8 + sponge_ef_folds = 10 + sponge_ef_mscor = 0.1 + sponge_ef_fdr = 0.05 + sponge_ef_enrichment_modules = 750 + sponge_ef_enrichment_bins = 100 + sponge_ef_enrichment_min = 60 + sponge_ef_enrichment_max = 2000 + sponge_ef_enrichment_expr = 10 + sponge_ef_enrichment_method = "OE" + // MultiQC options skip_fastqc = false multiqc_config = null diff --git a/nextflow_schema.json b/nextflow_schema.json index 93a30639..6aad660c 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -208,6 +208,89 @@ "description": "Determins whether to apply elastic net regression filtering or not.", "help_text": "Option to filter with elastic net.", "default": true + }, + + "sponge_coeff_threshold": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Threshold to cross for a regression coefficient to be called significant.", + "help_text": "Option to filter with different coefficient thresholds.", + "default": -0.05, + "minimum": -1 + }, + "sponge_ef_training": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Percentage used for training set size.", + "help_text": "Control the train datafram size", + "default": 0.8 + }, + "sponge_ef_folds": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Number of folds used in cross validation while calibrating 'SpongingActivity Model'.", + "help_text": "This parameter is used in the 'calibrate_model' function of the SPONGE module. Use it to control how many folds are computed in training.", + "default": 10, + "minimum": 2 + }, + "sponge_ef_mscor": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Filters interactions in the computed network based on their mscor. An interaction needs a more significant mscor than this threshold in order to stay inside the network.", + "help_text": "This parameter is used in the 'filter_ceRNA_network' function of the SPONGE module. Use it to change the mscor threshold while filtering the network.", + "default": 0.01 + }, + "sponge_ef_fdr": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "False discovery rate for padj ceRNA interactions.", + "help_text": "This parameter is used in the 'filter_ceRNA_network' function of the SPONGE module. Use it to adjust the false discovery rate.", + "default": 0.05 + }, + "sponge_ef_enrichment_modules": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Defines the maximum number of top modules (based on centrality), ensuring that only the most important or influential modules are retained.", + "help_text": "This parameter is used in the 'get_central_modules' function of the SPONGE module. It is used to limits the number of top-ranked modules returned for further processing.", + "default": 750 + }, + "sponge_ef_enrichment_bins": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "An integer specifying the bin size for the Overall Enrichment (OE) method. Bins are used to group genes for the enrichment calculation.", + "help_text": "This parameter is used in the 'enrichment_modules' function of the SPONGE module. Use it to finetune the enichment analysis of the gene expression.", + "default": 100 + }, + "sponge_ef_enrichment_min": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "An integer representing the minimum number of expressed genes required in a module for enrichment analysis.", + "help_text": "This parameter is used in the 'enrichment_modules' function of the SPONGE module. Use it to finetune the enichment analysis of the gene expression.", + "default": 60, + "minimum": 1 + }, + "sponge_ef_enrichment_max": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "An integer specifying the maximum number of genes allowed in a module for it to be included.", + "help_text": "This parameter is used in the 'enrichment_modules' function of the SPONGE module. Use it to finetune the enichment analysis of the gene expression.", + "default": 2000 + }, + "sponge_ef_enrichment_expr": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Minimum amount of expression required for enrichment analysis.", + "help_text": "This parameter is used in the 'enrichment_modules' function of the SPONGE module. Use it to control the minimum amount of expression required for enrichment analysis.", + "default": 10, + "minimum": 1 + }, + "sponge_ef_enrichment_method": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "A string specifying the enrichment method to use. Available options are 'OE' for Overall Enrichment and 'gsva' for Gene Set Variation Analysis", + "pattern": "^(OE|gsva)", + "help_text": "Select one of two enrichment methods for sponge effects.", + "default": "OE" } } }, diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index dfa2c224..2faaf900 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -4,6 +4,7 @@ include { DESEQ2_NORMALIZATION } from '../../modules/local/deseq2/nor include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' include { SPONGE } from '../../modules/local/sponge' +include { SPONGE_EFFECTS } from '../../modules/local/sponge_effects' // SUBWORKFLOWS include { MIRNA_BINDINGSITES } from './mirna/mirna_bindingsites' @@ -83,6 +84,9 @@ workflow MIRNA_PREDICTION { // if (params.sponge) SPONGE(MIRNA_BINDINGSITES.out.binding_sites, tx_counts, ch_mirna_filtered) + ch_versions = ch_versions.mix(SPONGE.out.versions) + SPONGE_EFFECTS(SPONGE.out.sponge_data) + emit: versions = ch_versions From e2aa28ee99849b6f787e4ab208d79b529c87f699 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Fri, 6 Sep 2024 12:56:32 +0200 Subject: [PATCH 08/53] solving version conflict in container --- modules/local/sponge_effects/main.nf | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge_effects/main.nf index 6c24c7ae..b2d4ca3f 100644 --- a/modules/local/sponge_effects/main.nf +++ b/modules/local/sponge_effects/main.nf @@ -4,8 +4,8 @@ process SPONGE_EFFECTS { conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? - 'oras://community.wave.seqera.io/library/bioconductor-rtracklayer_bioconductor-sponge_r-base_r-doparallel_pruned:16ef0e7778b29e70' : - 'community.wave.seqera.io/library/bioconductor-rtracklayer_bioconductor-sponge_r-base_r-doparallel_pruned:74e394923e2c369a' }" + 'oras://community.wave.seqera.io/library/bioconductor-sponge_r-base_r-data.table_r-doparallel_pruned:6546daac72b5cf47' : + 'community.wave.seqera.io/library/bioconductor-sponge_r-base_r-data.table_r-doparallel_pruned:75a4fa44f511e1d4' }" input: tuple val(meta), path(sponge_data) From 50628d52a6619c64a6e7d51d016aa53727b8d587 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 11 Sep 2024 12:04:16 +0200 Subject: [PATCH 09/53] removing deseq2 norm from sponge template --- modules/local/sponge/main.nf | 5 ++--- modules/local/sponge/templates/sponge.R | 14 -------------- 2 files changed, 2 insertions(+), 17 deletions(-) diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/main.nf index 4edaccb0..8947181d 100644 --- a/modules/local/sponge/main.nf +++ b/modules/local/sponge/main.nf @@ -4,8 +4,8 @@ process SPONGE { conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? - 'oras://community.wave.seqera.io/library/bioconductor-deseq2_bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:379bbce95f2c4913' : - 'community.wave.seqera.io/library/bioconductor-deseq2_bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:f38bbe7441604bcc' }" + 'oras://community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:086ecad7b1034ff0' : + 'community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:e79cb4c59aecf7ba' }" input: tuple val(meta), path(binding_sites) @@ -34,7 +34,6 @@ process SPONGE { cat <<-END_VERSIONS > versions.yml "${task.process}": - bioconductor-deseq2: \$(Rscript -e "library(DESeq2); cat(as.character(packageVersion('DESeq2')))") bioconductor-sponge: \$(Rscript -e "library(SPONGE); cat(as.character(packageVersion('SPONGE')))") r-visnetwork: \$(Rscript -e "library(visNetwork); cat(as.character(packageVersion('visNetwork')))") r-doparallel: \$(Rscript -e "library(doParallel); cat(as.character(packageVersion('doParallel')))") diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/templates/sponge.R index 59ca8600..f1ab5fad 100644 --- a/modules/local/sponge/templates/sponge.R +++ b/modules/local/sponge/templates/sponge.R @@ -4,7 +4,6 @@ library(SPONGE) library(visNetwork) library(doParallel) library(foreach) -library(DESeq2) circ_mRNA_subnetwork <- function(interactions, pattern) { return(interactions[ @@ -13,15 +12,6 @@ circ_mRNA_subnetwork <- function(interactions, pattern) { ]) } -normalize_data <- function(data){ - samples <- colnames(data) - meta <- data.frame(row.names = samples) - data <- as.matrix(data) - dds <- DESeq2::DESeqDataSetFromMatrix(countData = round(data + 1), colData = meta, design = ~ 1) - dds <- DESeq2::estimateSizeFactors(dds) - return(DESeq2::counts(dds, normalized=TRUE)) -} - # load binding sites matrix bindingsites <- read.table("${binding_sites}", sep = "\\t", header = TRUE, check.names = FALSE) rownames(bindingsites) <- bindingsites[, 1] @@ -32,8 +22,6 @@ bindingsites_matrix <- as.matrix(bindingsites) # load gene expression genes <- read.csv("${gene_expr}", sep = "\\t", row.names = "tx") genes <- subset(genes, select = -gene_id) -# prep for DESeq2 -gene_expr <- normalize_data(as.matrix(genes)) gene_expr <- t(as.matrix(genes)) @@ -187,7 +175,6 @@ save.image(file = "sponge.RData") ################################################ ################################################ -deseq2.version <- as.character(packageVersion('DESeq2')) sponge.version <- as.character(packageVersion('SPONGE')) visnetwork.version <- as.character(packageVersion('visNetwork')) doparallel.version <- as.character(packageVersion('doParallel')) @@ -196,7 +183,6 @@ foreach.version <- as.character(packageVersion('foreach')) writeLines( c( '"${task.process}":', - paste(' bioconductor-deseq2:', deseq2.version), paste(' bioconductor-sponge:', sponge.version), paste(' r-visnetwork:', visnetwork.version), paste(' r-doparallel:', doparallel.version), From d9144a3989cd408d1158cecc007ca04a5340582c Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 11 Sep 2024 12:04:56 +0200 Subject: [PATCH 10/53] adding additional deseq2 normalization process for tx counts --- .../environment.yml | 0 .../main.nf | 2 +- .../templates/deseq_normalization.R | 0 modules/local/deseq2/tx_normalization/main.nf | 32 +++++++++++++++++ .../templates/tx_deseq_normalization.R | 36 +++++++++++++++++++ 5 files changed, 69 insertions(+), 1 deletion(-) rename modules/local/deseq2/{normalization => mirna_normalization}/environment.yml (100%) rename modules/local/deseq2/{normalization => mirna_normalization}/main.nf (96%) rename modules/local/deseq2/{normalization => mirna_normalization}/templates/deseq_normalization.R (100%) create mode 100644 modules/local/deseq2/tx_normalization/main.nf create mode 100644 modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R diff --git a/modules/local/deseq2/normalization/environment.yml b/modules/local/deseq2/mirna_normalization/environment.yml similarity index 100% rename from modules/local/deseq2/normalization/environment.yml rename to modules/local/deseq2/mirna_normalization/environment.yml diff --git a/modules/local/deseq2/normalization/main.nf b/modules/local/deseq2/mirna_normalization/main.nf similarity index 96% rename from modules/local/deseq2/normalization/main.nf rename to modules/local/deseq2/mirna_normalization/main.nf index 74cb8b5a..0af4fa1a 100644 --- a/modules/local/deseq2/normalization/main.nf +++ b/modules/local/deseq2/mirna_normalization/main.nf @@ -1,4 +1,4 @@ -process DESEQ2_NORMALIZATION { +process MIRNA_NORMALIZATION { tag "$meta.id" label 'process_single' diff --git a/modules/local/deseq2/normalization/templates/deseq_normalization.R b/modules/local/deseq2/mirna_normalization/templates/deseq_normalization.R similarity index 100% rename from modules/local/deseq2/normalization/templates/deseq_normalization.R rename to modules/local/deseq2/mirna_normalization/templates/deseq_normalization.R diff --git a/modules/local/deseq2/tx_normalization/main.nf b/modules/local/deseq2/tx_normalization/main.nf new file mode 100644 index 00000000..6f322e16 --- /dev/null +++ b/modules/local/deseq2/tx_normalization/main.nf @@ -0,0 +1,32 @@ +process TX_NORMALIZATION { + tag "$meta.id" + label 'process_single' + + conda "${moduleDir}/environment.yml" + container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? + 'https://depot.galaxyproject.org/singularity/bioconductor-deseq2:1.34.0--r41hc247a5b_3' : + 'biocontainers/bioconductor-deseq2:1.34.0--r41hc247a5b_3' }" + + input: + tuple val(meta), path(counts) + + output: + tuple val(meta), path("${meta.id}.normalized_counts.tsv"), emit: normalized + path "versions.yml" , emit: versions + + when: + task.ext.when == null || task.ext.when + + script: + template 'tx_deseq_normalization.R' + + stub: + """ + touch ${meta.id}.normalized_counts.tsv + + cat <<-END_VERSIONS > versions.yml + "${task.process}": + bioconductor-deseq2: \$(Rscript -e "library(DESeq2); cat(as.character(packageVersion('DESeq2')))") + END_VERSIONS + """ +} diff --git a/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R b/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R new file mode 100644 index 00000000..54ac5ee2 --- /dev/null +++ b/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R @@ -0,0 +1,36 @@ +#!/usr/bin/env Rscript + +library(DESeq2) + +raw_counts <- read.table("$counts", sep = "\\t", header = TRUE, stringsAsFactors = FALSE, check.names = FALSE) +raw_counts <- raw_counts[ , -2] # drop gene ids +rownames(raw_counts) <- raw_counts\$tx +data <- round(raw_counts[, -1]) + +samples <- colnames(raw_counts)[-c(1)] + + +transcript_names <- data.frame(tx = raw_counts\$tx, order = seq_len(nrow(raw_counts))) + +# normalize using DeSeq2, Library Size Estimation +meta_data <- data.frame(samples) +row.names(meta_data) <- meta_data\$samples +all(colnames(data) %in% rownames(meta_data)) +all(colnames(data) == rownames(meta_data)) + +dds <- DESeqDataSetFromMatrix(countData = data, colData = meta_data, design = ~ 1) +dds <- estimateSizeFactors(dds) +sizeFactors(dds) +normalized_counts <- DESeq2::counts(dds, normalized = TRUE) + +# add tx IDs back to counts table +merged_data <- merge(transcript_names, normalized_counts, + by.x = "tx", by.y = "row.names") + +merged_data <- merged_data[order(merged_data\$order), ] + +norm_data <- subset(merged_data, select = -c(order)) + +write.table(norm_data, paste0("${meta.id}.normalized_counts.tsv"), quote = FALSE, sep = "\\t", row.names = FALSE) + +# TODO: (Can be done later) Add support for Samplesheet so that we can eliminate batch effects From ae37fb8bc61e285060e6ea4e462e3303aa81e089 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 11 Sep 2024 12:05:25 +0200 Subject: [PATCH 11/53] removing pacman call in sponge_effects --- .../sponge_effects/templates/sponge_effects.R | 113 ++++++++++++++---- 1 file changed, 93 insertions(+), 20 deletions(-) diff --git a/modules/local/sponge_effects/templates/sponge_effects.R b/modules/local/sponge_effects/templates/sponge_effects.R index 78ccf733..d36fdad5 100644 --- a/modules/local/sponge_effects/templates/sponge_effects.R +++ b/modules/local/sponge_effects/templates/sponge_effects.R @@ -1,7 +1,16 @@ #!/usr/bin/env Rscript -if(!require(pacman)) install.packages("pacman", repos = "http://cran.us.r-project.org") -pacman::p_load(SPONGE, doParallel, foreach, dplyr, visNetwork, pheatmap, ggplot2, reshape2, ggpubr, rtracklayer) +library("SPONGE") +library("rtracklayer") +library("doParallel") +library("foreach") +library("dplyr") +library("visNetwork") +library("pheatmap") +library("ggplot2") +library("reshape2") +library("ggpubr") +library("GSVA") ######################## ## GENERAL FUNCTIONS ### @@ -66,6 +75,7 @@ plot_network <- function(ceRNA_network, signif_hits = NULL, } + circ.mRNA.subnetwork <- function(interactions, pattern){ return(interactions[ (grepl(pattern, interactions\$geneA) & !grepl(pattern, interactions\$geneB)) | @@ -76,7 +86,7 @@ circ.mRNA.subnetwork <- function(interactions, pattern){ # plot model performance (spongEffects) plot_performance <- function (trained_model, central_genes_model = NULL, random_model, training_dataset_name = "TCGA", - testing_dataset_name = "TCGA", subtypes){ + testing_dataset_name = "TCGA", subtypes) { trained.model <- trained_model CentralGenes.model <- central_genes_model Random.model <- random_model @@ -177,7 +187,7 @@ plot_performance <- function (trained_model, central_genes_model = NULL, plot_modules <- function (trained_model, k_modules = 25, k_modules_red = 10, - text_size = 16){ + text_size = 16) { final.model <- trained_model\$Model\$finalModel Variable.importance <- importance(final.model) %>% as.data.frame() %>% tibble::rownames_to_column("Module") %>% arrange(desc(MeanDecreaseGini)) @@ -209,7 +219,7 @@ plot_hmap <- function (trained_model, sampleIDs, Modules_to_Plot = 5, show.rownames = F, - show.colnames = F){ + show.colnames = F) { if (label %in% colnames(meta_data) & sampleIDs %in% colnames(meta_data)) { final.model <- trained_model\$Model\$finalModel Variable.importance <- importance(final.model) %>% as.data.frame() %>% @@ -248,7 +258,7 @@ plot_target_gene_expressions <- function(target, target_genes, annotation = NULL, split = "condition", unit = "counts", show_rows = TRUE, - annotation_colors = NULL){ + annotation_colors = NULL) { # get target expression target_expression <- gene_expression[ ,target, drop = FALSE] # get target genes expressions @@ -345,6 +355,67 @@ plot_miRNAs_per_gene <- function(target, genes_miRNA_candidates, return(bars) } +################################################################# +## SPONGE FUNCTIONS DUE TO VERSION CONFLICTS WITH RTRACKLAYSER ## +################################################################# + +fn_filter_network <- function(network, mscor.threshold = .1, padj.threshold = .01) { + network %>% filter(mscor > mscor.threshold & p.adj < padj.threshold) +} + +fn_weighted_degree <- function(network, undirected = T, Alpha = 1) { + # Format input matrix by using numeric as node IDs + Nodes <- data.frame(Nodes = union(network\$geneA, network\$geneB), + Nodes_numeric = seq(1, length(union(network\$geneA, network\$geneB)))) + + geneA.numeric <- Nodes\$Nodes_numeric[match(network\$geneA, Nodes\$Nodes)] + geneB.numeric <- Nodes\$Nodes_numeric[match(network\$geneB, Nodes\$Nodes)] + + Input.network <- data.frame(Sender = geneA.numeric, Receiver = geneB.numeric, Weight = network\$mscor) + + if (undirected) { + # Define networks as undirected + Undirected.net <- Input.network %>% tnet::symmetrise_w() + Weighted_degree <- tnet::degree_w(Undirected.net, alpha = Alpha) %>% as.data.frame() + Nodes\$Weighted_degree <- Weighted_degree\$output[match(Weighted_degree\$node, Nodes\$Nodes_numeric)] + return(Nodes) + } +} + +filter_ceRNA_network <- function(sponge_effects, + Node_Centrality = NA, + add_weighted_centrality = T, + mscor.threshold = NA, + padj.threshold = NA) { + + #Filter SPONGE network for significant edges + Sponge.filtered <- sponge_effects %>% + fn_filter_network(mscor.threshold = mscor.threshold, padj.threshold = padj.threshold) + + # Some gene columns from SPONGEdb start with an uppercase G, so we need to adjust it just in case + if("GeneA" %in% colnames(Sponge.filtered)) { + Sponge.filtered = Sponge.filtered %>% rename(geneA = GeneA) + } + if("GeneB" %in% colnames(Sponge.filtered)) { + Sponge.filtered = Sponge.filtered %>% rename(geneB = GeneB) + } + Node_Centrality <- Node_Centrality %>% dplyr::filter(gene %in% Sponge.filtered\$geneA | gene %in% Sponge.filtered\$geneB) + + # Calculate weighted centrality scores and add them to the ones present in SpongeDB + if(!add_weighted_centrality) { + sponge_network_centralites <- list(Sponge.filtered) + names(sponge_network_centralites) <- c("Sponge.filtered") + } + else { + Nodes <- fn_weighted_degree(Sponge.filtered, undirected = T, Alpha = 1) + Node_Centrality <- Node_Centrality %>% + mutate(Weighted_Degree = Nodes\$Weighted_degree[match(Node_Centrality\$gene, Nodes\$Nodes)]) + sponge_network_centralites <- list(Sponge.filtered,Node_Centrality) + names(sponge_network_centralites) <- c("Sponge.filtered","Node_Centrality") + } + return(sponge_network_centralites) +} + #---------------------------OUTPUT DIR-------------------------------- ROOT = "." # create plot directory @@ -362,16 +433,16 @@ colnames(gene.ens.all) <- c("ensembl_gene_id", "hgnc_symbol", "gene_type") rownames(gene.ens.all) <- gene.ens.all\$hgnc_symbol #---------------------------PARAMETERS-------------------------------- -mscor.threshold = 0.001 # "${params.sponge_ef_mscor}" -padj.threshold = 0.7 # "${params.sponge_ef_fdr}" -modules_cutoff = "${params.sponge_ef_enrichment_modules}" -bin.size = "${params.sponge_ef_enrichment_bins}" -min.size = "${params.sponge_ef_enrichment_min}" -max.size = "${params.sponge_ef_enrichment_max}" -min.expr = "${params.sponge_ef_enrichment_expr}" +mscor.threshold = 0.001 # ${params.sponge_ef_mscor} +padj.threshold = 0.7 # ${params.sponge_ef_fdr} +modules_cutoff = ${params.sponge_ef_enrichment_modules} +bin.size = ${params.sponge_ef_enrichment_bins} +min.size = ${params.sponge_ef_enrichment_min} +max.size = ${params.sponge_ef_enrichment_max} +min.expr = ${params.sponge_ef_enrichment_expr} method = "${params.sponge_ef_enrichment_method}" -split_training = "${params.sponge_ef_training}" -folds = "${params.sponge_ef_folds}" +split_training = ${params.sponge_ef_training} +folds = ${params.sponge_ef_folds} #---------------------------PARALLEL BACKGROUND----------------------- num.of.cores <- 8 @@ -416,7 +487,7 @@ test_mirna_expr <- mir_expr[rownames(mir_expr) %in% test.meta\$sampleIDs, ] #-------------------------CE RNA SPLITTING------------------------ # MALTE TODO: no circ interactions -> empty df # MALTE TODO: hard code path for now in template -ceRNA_interactions_sign <- read.table("/nfs/home/students/mweyrich/sponge/ceRNA_interactions_sign.tsv", header = TRUE, check.names = FALSE) +ceRNA_interactions_sign <- read.table("/nfs/data3/CIRCEST/runs/sponging/sponge_res/ceRNA_interactions_sign.tsv", header = TRUE, check.names = FALSE, sep = "\\t") ceRNA_interactions_fdr <- ceRNA_interactions_sign[which(ceRNA_interactions_sign\$p.adj < padj.threshold), ] ceRNA_interactions_fdr <- circ.mRNA.subnetwork(ceRNA_interactions_fdr, "circ") @@ -661,24 +732,26 @@ save.image(file.path(ROOT, "spongEffects.RData")) ################################################ ################################################ -r.version <- strsplit(version[['version.string']], ' ')[[1]][3] -rtracklayer.version <- as.character(packageVersion('rtracklayer')) -sponge.version <- as.character(packageVersion('SPONGE')) doparallel.version <- as.character(packageVersion('doParallel')) dplyr.version <- as.character(packageVersion('dplyr')) foreach.version <- as.character(packageVersion('foreach')) ggplot2.version <- as.character(packageVersion('ggplot2')) ggpubr.version <- as.character(packageVersion('ggpubr')) +gsva.version <- as.character(packageVersion('GSVA')) pheatmap.version <- as.character(packageVersion('pheatmap')) +r.version <- strsplit(version[['version.string']], ' ')[[1]][3] reshape2.version <- as.character(packageVersion('reshape2')) +rtracklayer.version <- as.character(packageVersion('rtracklayer')) +sponge.version <- as.character(packageVersion('SPONGE')) visnetwork.version <- as.character(packageVersion('visNetwork')) writeLines( c( '"${task.process}":', - paste(' r-base:', r.version) + paste(' bioconductor-gsva:', gsva.version) paste(' bioconductor-rtracklayer', rtracklayer.version) paste(' bioconductor-sponge', sponge.version) + paste(' r-base:', r.version) paste(' r-doparallel', doparallel.version) paste(' r-dplyr', dplyr.version) paste(' r-foreach', foreach.version) From 20f8609e4ed1c4a96c09023ac9b6543c28dc3467 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 11 Sep 2024 12:05:55 +0200 Subject: [PATCH 12/53] updating sponge_effects container to include gsva --- modules/local/sponge_effects/main.nf | 6 ++++-- 1 file changed, 4 insertions(+), 2 deletions(-) diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge_effects/main.nf index b2d4ca3f..8fadae57 100644 --- a/modules/local/sponge_effects/main.nf +++ b/modules/local/sponge_effects/main.nf @@ -4,8 +4,10 @@ process SPONGE_EFFECTS { conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? - 'oras://community.wave.seqera.io/library/bioconductor-sponge_r-base_r-data.table_r-doparallel_pruned:6546daac72b5cf47' : - 'community.wave.seqera.io/library/bioconductor-sponge_r-base_r-data.table_r-doparallel_pruned:75a4fa44f511e1d4' }" + 'oras://community.wave.seqera.io/library/bioconductor-gsva_bioconductor-rtracklayer_bioconductor-sponge_r-base_pruned:ac5be0e145e964fc' : + 'community.wave.seqera.io/library/bioconductor-gsva_bioconductor-rtracklayer_bioconductor-sponge_r-base_pruned:5fad30741cf73551' }" + + input: tuple val(meta), path(sponge_data) From 656c76e648bac300cbf19051be21ea20de3529ec Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 11 Sep 2024 12:06:59 +0200 Subject: [PATCH 13/53] adding and renaming deseq2_normalisation processes --- subworkflows/local/mirna_prediction.nf | 27 +++++++++++++++++--------- 1 file changed, 18 insertions(+), 9 deletions(-) diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index 2faaf900..b7d4b0c2 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -1,10 +1,11 @@ // MODULES -include { BIOAWK as ADD_BACKSPLICE } from '../../modules/nf-core/bioawk' -include { DESEQ2_NORMALIZATION } from '../../modules/local/deseq2/normalization' -include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' -include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' -include { SPONGE } from '../../modules/local/sponge' -include { SPONGE_EFFECTS } from '../../modules/local/sponge_effects' +include { BIOAWK as ADD_BACKSPLICE } from '../../modules/nf-core/bioawk' +include { MIRNA_NORMALIZATION } from '../../modules/local/deseq2/mirna_normalization' +include { TX_NORMALIZATION } from '../../modules/local/deseq2/tx_normalization' +include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' +include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' +include { SPONGE } from '../../modules/local/sponge' +include { SPONGE_EFFECTS } from '../../modules/local/sponge_effects' // SUBWORKFLOWS include { MIRNA_BINDINGSITES } from './mirna/mirna_bindingsites' @@ -28,9 +29,9 @@ workflow MIRNA_PREDICTION { if (params.mirna_expression) { - ch_mirna_normalized = DESEQ2_NORMALIZATION(ch_mirna).normalized + ch_mirna_normalized = MIRNA_NORMALIZATION(ch_mirna).normalized - ch_versions = ch_versions.mix(DESEQ2_NORMALIZATION.out.versions) + ch_versions = ch_versions.mix(MIRNA_NORMALIZATION.out.versions) ch_mirna_filtered = MIRNA_FILTERING(ch_mirna_normalized, params.mirna_min_sample_percentage, @@ -83,8 +84,16 @@ workflow MIRNA_PREDICTION { } // if (params.sponge) - SPONGE(MIRNA_BINDINGSITES.out.binding_sites, tx_counts, ch_mirna_filtered) + + + ch_tx_normalized = TX_NORMALIZATION(tx_counts.map{ it -> [[id: 'tx'], it]}).normalized + + ch_versions = ch_versions.mix(TX_NORMALIZATION.out.versions) + + SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_tx_normalized, ch_mirna_filtered) + ch_versions = ch_versions.mix(SPONGE.out.versions) + SPONGE_EFFECTS(SPONGE.out.sponge_data) From 79bd2988f58e59291ba69a1a016843cad305cabb Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 12 Sep 2024 09:41:09 +0200 Subject: [PATCH 14/53] removing redundant param --- nextflow_schema.json | 9 --------- 1 file changed, 9 deletions(-) diff --git a/nextflow_schema.json b/nextflow_schema.json index 6aad660c..83647df9 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -209,15 +209,6 @@ "help_text": "Option to filter with elastic net.", "default": true }, - - "sponge_coeff_threshold": { - "type": "number", - "fa_icon": "fas fa-circle-notch", - "description": "Threshold to cross for a regression coefficient to be called significant.", - "help_text": "Option to filter with different coefficient thresholds.", - "default": -0.05, - "minimum": -1 - }, "sponge_ef_training": { "type": "number", "fa_icon": "fas fa-circle-notch", From d44046f20fde43ec919f5a89316b1a16c80a5112 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 12 Sep 2024 09:41:36 +0200 Subject: [PATCH 15/53] fixing input for tx_normalization --- subworkflows/local/mirna_prediction.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index b7d4b0c2..fd2892cb 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -86,7 +86,7 @@ workflow MIRNA_PREDICTION { // if (params.sponge) - ch_tx_normalized = TX_NORMALIZATION(tx_counts.map{ it -> [[id: 'tx'], it]}).normalized + ch_tx_normalized = TX_NORMALIZATION(tx_counts).normalized ch_versions = ch_versions.mix(TX_NORMALIZATION.out.versions) From 8d685dbe4774fc4f5415482a8b3eac5797de99ce Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:45:28 +0200 Subject: [PATCH 16/53] adding versions file to R script of tx_normalization --- .../templates/tx_deseq_normalization.R | 18 ++++++++++++++++++ 1 file changed, 18 insertions(+) diff --git a/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R b/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R index 54ac5ee2..6d6f86c8 100644 --- a/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R +++ b/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R @@ -34,3 +34,21 @@ norm_data <- subset(merged_data, select = -c(order)) write.table(norm_data, paste0("${meta.id}.normalized_counts.tsv"), quote = FALSE, sep = "\\t", row.names = FALSE) # TODO: (Can be done later) Add support for Samplesheet so that we can eliminate batch effects + + +################################################ +################################################ +## VERSIONS FILE ## +################################################ +################################################ + +r.version <- strsplit(version[['version.string']], ' ')[[1]][3] +deseq2.version <- as.character(packageVersion('DESeq2')) + +writeLines( + c( + '"${task.process}":', + paste(' r-base:', r.version), + paste(' bioconductor-deseq2:', deseq2.version) + ), +'versions.yml') From aa2db970e4d1790d3ac9b4eb2551373f54af5492 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:45:53 +0200 Subject: [PATCH 17/53] formatting --- modules/local/sponge/main.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/main.nf index 8947181d..071d500a 100644 --- a/modules/local/sponge/main.nf +++ b/modules/local/sponge/main.nf @@ -14,12 +14,12 @@ process SPONGE { output: - path "versions.yml" , emit: versions tuple val(meta), path("sponge.RData") , emit: sponge_data path "circRNAs_as_ceRNAs.tsv" , emit: cernas path "total_plots.pdf" , emit: total_plots path "simulation_plots.pdf" , emit: simulation_plots path "circRNA_plots.pdf" , emit: circ_plots + path "versions.yml" , emit: versions when: From b04afc6999f5d36129a0743bb75922e153c9c764 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:46:16 +0200 Subject: [PATCH 18/53] adding versions to output of sponge effects --- modules/local/sponge_effects/main.nf | 3 +-- 1 file changed, 1 insertion(+), 2 deletions(-) diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge_effects/main.nf index 8fadae57..e2047f21 100644 --- a/modules/local/sponge_effects/main.nf +++ b/modules/local/sponge_effects/main.nf @@ -7,13 +7,12 @@ process SPONGE_EFFECTS { 'oras://community.wave.seqera.io/library/bioconductor-gsva_bioconductor-rtracklayer_bioconductor-sponge_r-base_pruned:ac5be0e145e964fc' : 'community.wave.seqera.io/library/bioconductor-gsva_bioconductor-rtracklayer_bioconductor-sponge_r-base_pruned:5fad30741cf73551' }" - - input: tuple val(meta), path(sponge_data) output: // TODO + path "versions.yml" , emit: versions when: From cb7f82f37c7ac8ea0d6ea9d5297cce33855452c0 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:46:33 +0200 Subject: [PATCH 19/53] adding 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zaOZowg_BqLXQS4~4SpYet3y2pb^l77HTKo+l27z&r2Mz+@U7k2fAEQ3LS4;o`#)@) zIA|Yloa($PhSoPcEDu<|uy#oN7FI{R`P%o-i*dB5_g}0F`k@Xzo_z88UwO^Aw{?~X z8D8A-3lHPD!HyU5fccqEu>Ok!8K%9)BtJ`ZF3{^65N%?!$p~AJ_h$cKt32yUHJLd|H3b-lLWW`wBSb zR`DU!iCx||zI|U4G3Ewd9QzG3^9)Z9zDZENyqF- z{8rv~#u+n`IO6hy^?w)p&hsxmjxb)lcHhJQbE*2VWIF6AHlk7o^`2x z^}x%Ao*g}Tm)?0*?BsRG_aSZ`j>(u;)<04^YwTckoZip=cD{(YA&+~pyNG0Fe&E#& zUYlRX;)|z_+EGV-?D*m3f!8lQTy=v~?%8yD-|8om1Pmp5Gbws?5? z!pulKyo|X;-`8Dw_Ap6LCf~ZhBcAoj_&G1)w;yv0Pp=)k{u^I*>V)5lgXafphhAOI zWEo^*9A#bCKAd=YKGHb5&Va3}&Qr8wKJyW-XHe(YdUd|2Jiq-GMQ_~^x9Rx9J_M@Mh;xGPx versions.yml + "${task.process}": + miranda: \$(echo \$(miranda -v | sed -n 4p | sed 's/^.*miranda v//; s/microRNA.*\$//' )) + RNAplfold: \$(echo \$(RNAplfold -V | sed 's/^.*RNAplfold //' )) + RNAduplex: \$(echo \$(RNAduplex -V | sed 's/^.*RNAduplex //' )) + python: \$(python --version | sed 's/Python //g') + numpy: \$(python -c "import numpy; print(numpy.__version__)") + scikit-learn: \$(python -c "import sklearn; print(sklearn.__version__)") + pymysql: \$(python -c "import pymysql; print(pymysql.__version__)") + END_VERSIONS + """ +} diff --git a/modules/local/tarpmir/templates/TarPmiR_threading.py b/modules/local/tarpmir/templates/TarPmiR_threading.py new file mode 100644 index 00000000..d6aa942f --- /dev/null +++ b/modules/local/tarpmir/templates/TarPmiR_threading.py @@ -0,0 +1,755 @@ +#!/usr/bin/env python + +""" +Last update: 02/02/2016 +author: jun ding +usage: python TarPmiR.py -a -b -m -p +""" +import pdb,sys,os,re,math,getopt +try: + from urllib2 import urlopen +except: + from urllib.request import urlopen + +import urllib +import subprocess +import pickle +import uuid +import pymysql +import ssl +import numpy as np +# threading +import threading +import time +import concurrent.futures + +try: + ssl._create_default_https_context = ssl._create_unverified_context +except: + pass + +#------------------------------------------------ +try: + db1=pymysql.connect("genome-mysql.cse.ucsc.edu",'genome') + cur1=db1.cursor() + cur1.execute("use hg38") +except: + pass +#--------------------------------------------------------------------- + +#*********************************************************************** +#======================================================================= +# global functions# + +def format_yaml_like(data: dict, indent: int = 0) -> str: + """Formats a dictionary to a YAML-like string. + + Args: + data (dict): The dictionary to format. + indent (int): The current indentation level. + + Returns: + str: A string formatted as YAML. + """ + yaml_str = "" + for key, value in data.items(): + spaces = " " * indent + if isinstance(value, dict): + yaml_str += f"{spaces}{key}:\\n{format_yaml_like(value, indent + 1)}" + else: + yaml_str += f"{spaces}{key}: {value}\\n" + return yaml_str + +def filterBS(A): + def mergeBS(a,b): + a_bs=a[2].split(',') + b_bs=b[2].split(',') + if float(a[-1])>float(b[-1]): + return a + elif float(a[-1])int(b_bs[1])-int(b_bs[0]): + return a + else: + return b + + def overlap(a,b): + a=a.split(',') + b=b.split(',') + flag=(int(a[1])-int(b[0]))*(int(a[0])-int(b[1])) + if flag<=0: + return True + else: + return False + + for i in range(len(A)-1): + for j in range(i+1,len(A)): + if A[i]!=[] and A[j]!=[]: + if overlap(A[i][2],A[j][2]): + A[i]=mergeBS(A[i],A[j]) + A[j]=[] + A=[item for item in A if item!=[]] + return A + +# changed to hg38 +def get_conservation(pos): + url="https://genome.ucsc.edu/cgi-bin/hgTables?" + form_data={'hgsid':'385332177_fMwuaEoYIaAfIxVs6VEa6hgHN1kA', + 'clade':'mammal', + 'org':'human', + 'db':'hg38', + 'hgta_group':'compGeno', + 'hgta_track':'cons46way', + 'hgta_table':'phyloP46wayAll', + 'hgta_regionType':'range', + 'position':pos, + 'hgta_outputType':'wigData', + 'hgta_outFileName':'1', + 'hgta_doTopSubmit':'get output'} + params=urllib.urlencode(form_data) + response=urlopen(url,params) + data=response.read() + data=data.split('\\n') + data=data[1:] + out=[] + for i in data: + if (len(i)>0) and (i[0]!="#")and (i[0]!='v'): + ii=i.split() + ii=[int(ii[0]),float(ii[1])] + out.append(ii) + return out + + + +def scan(seq,m,cut): + dN={"A":0,"C":1,"G":2,"T":3} + maxS=maxScore(m) + loc=[] + for i in range(len(seq)-len(m)+1): + sc_i=0 + for j in range(len(m)): + seqij=seq[i+j] + if seqij!="N": + sc=m[j][dN[seqij]] + else: + sc=0.0 + sc_i+=sc + if sc_i/maxS>=cut: + loc.append(i) + return loc + +def maxScore(m): + s=0 + for i in m: + s+=max(i) + return s + + +def get_ensGene(name): + pn=re.compile('N._') + row=None + if name[0:4]=='ENST': + cur1.execute('select * from hg19.ensGene where name="%s"'%(name)) + row=cur1.fetchone() + elif pn.search(name): + row=cur1.execute('select * from hg19.refGene where name="%s"'%(name)) + if row!=None: + row=[row[2],row[3],row[4],row[5],row[9],row[10]] + else: + row=[] + return row + +def revcom(A): + dN={"A":"T","C":"G","G":"C","T":"A","N":"N"} + A=[dN[item] for item in A] + A=A[::-1] + A="".join(A) + return A + +def get_seq(pos,strand): + link="http://genome.ucsc.edu/cgi-bin/das/hg19/dna?segment="+pos + f=urllib.urlopen(link) + lf=f.read() + lf=lf.split("")[0].split('>')[1] + lf=lf.split("\\n") + lf=[item for item in lf if item!=''] + lf="".join(lf) + lf=lf.upper() + if strand=="+": + seq=lf + else: + seq=revcom(lf) + return seq + +def check_seed(seedx,x): + dN={'A':'T','C':'G','G':'CT','U':'AG','T':'AG','N':'N'} + seedx=[dN[item] for item in seedx] + rc_seedx=seedx[::-1] + flag=1 + for i in range(len(x)): + if x[i] not in rc_seedx[i]: + flag=0 + break + return flag + +def progressbar(count, total, suffix=""): + bar_len = 60 + filled_len = int(round(bar_len * count / float(total))) + + percents = round(100.0 * count / float(total), 1) + bar = '=' * filled_len + '-' * (bar_len - filled_len) + + print('[%s] %s%s ...%s\\r' % (bar, percents, '%', suffix)) + +def longestStem(bb,bm): + #bb is the pairing output of miRNA from RNAduplex + ct=0 + A=[] + B=[] + pc=0 + key='(' + for i in bb: + if i==key: + ct+=1 + else: + A.append([ct,pc-ct]) + ct=0 + pc+=1 + A.append([ct,pc-ct]) + A=max(A) + + + pa=[] # pairing location in miRNA + pb=[] # pairing location in mRNA + for i in range(len(bb)): + if bb[i]=='(': + pa.append(i) + + for i in range(len(bm)-1,-1,-1): + if bm[i]==')': + pb.append(i) + + ss=bb[0:A[1]].count('(') # stem start + se=bb[0:A[1]+A[0]-1].count('(')# stem end + #pdb.set_trace() + return [pb[se],pb[ss]] + +#======================================================================= +#*********************************************************************** + + + +#======================================================================= +# File processing + +class File: + def __init__(self,file_path): + self.path=file_path + + def readInfo(self,sep): + f=open(self.path,'r') + lf=f.readlines() + f.close() + lf=[item.strip().split(sep) for item in lf] + return lf + + def readSeq(self): + f=open(self.path,'r') + lf=f.readlines() + f.close() + lf="".join(lf) + lf=lf.split(">")[1:] + for i in range(len(lf)): + lf[i]=lf[i].split('\\n') + lf[i]=[item.strip() for item in lf[i]] + lf[i]=["".join(lf[i][0]),''.join(lf[i][1:])] + return lf + + + +class miRNA: + def __init__(self,mi,mi_seq): + self.name=mi + self.seq=mi_seq + +class mRNA: + def __init__(self,m,seq): + self.name=m + self.seq=seq + self.acc=self.accessibility_plfold() + self.phy=self.phyloP() + + def accessibility_plfold(self): + W=80 + L=40 + sessionID='fn_'+str(uuid.uuid1()) + input_mseq='>'+sessionID+'\\n'+self.seq + input_mseq=input_mseq.encode() + pp=subprocess.Popen(["RNAplfold","-W", "80", "-L", "40","-u", "16"],stdout=subprocess.PIPE, stdin=subprocess.PIPE,stderr=subprocess.PIPE) + #pdb.set_trace() + out,err=pp.communicate(input=input_mseq) + pp.wait() + #pp.terminate() + f=open("%s_lunp"%(sessionID),'r') + lf=f.readlines() + f.close() + lf=[item.strip() for item in lf] + lf=[item for item in lf if len(item)!=0] + lf=lf[2:] + lf=[item.split('\t') for item in lf] + lf=[item[-1] for item in lf] + #pdb.set_trace() + #=== + try: + os.remove("%s_dp.ps"%(sessionID)) + os.remove("%s_lunp"%(sessionID)) + except: + pass + + return lf + + def phyloP(self): + try: + row=get_ensGene(self.name) + span=80000 + currentS=row[2] + currentE=currentS+span + cvm=[] + while(currentE0: + exons=row[4].split(',') + exons=[item for item in exons if item!=''] + exone=row[5].split(',') + exone=[item for item in exone if item!=''] + for i in range(len(exons)): + for j in range(int(exons[i]),int(exone[i])): + if j in dc: + cv.append(dc[j]) + else: + cv.append(0) + return cv + except: + return [] + + +class Interactions: + def __init__(self,mir,m): + self.mir=mir + self.m=m + + def cand_site(self): + #ss=self.seed_site() + es=self.energy_site() + return es + + def seed_site(self): + seed=self.mir.seq[1:16] + ss=[] + for i in range(len(self.m.seq)-len(self.mir.seq)+1): + x=self.m.seq[i:i+len(seed)] + flag=check_seed(seed,x) + if flag!=0: + ss.append(i+len(seed)) + out=[] + x=24 + for i in ss: + out.append(str(max(0,i-x))+","+str(i+1)) + return out + + def energy_site1(self): + S=4 + C=-15 + ip_seq=">"+self.mir.name+"\\n"+self.mir.seq+"\\n"+">"+self.m.name+"\\n"+self.m.seq + pp1=subprocess.Popen(["RNADuplex","-e", "5", "-s"],stdout=subprocess.PIPE, stdin=subprocess.PIPE,stderr=subprocess.PIPE) + out,err=pp1.communicate(input=ip_seq) + pp1.wait() + #pp1.terminate() + lf=[item for item in out.split('\\n') if len(item)>0] + lf=[item.strip() for item in lf if item[0]!=">"] + lf=[item.split() for item in lf] + lf=[item for item in lf if float(item[-1][1:-1])0] + out=[item for item in out if item[0]=='>' and item[1]!=">"] + out=[item.split("\\t") for item in out] + out=[",".join(item[5].split(" ")) for item in out] + out=[i for i in out if int(i.split(",")[1])-int(i.split(",")[0]) >= 5 and int(i.split(",")[1]) <= len(self.m.seq)] + try: + os.remove(intID+"_mir_seq.txt") + os.remove(intID+"_m_seq.txt") + except: + pass + return out + + +class binding: + def __init__(self,mir,m,pos): + self.mir=mir + self.m=m + self.p=pos + # features of each miRNA-mRNA binding site + [self.en,self.sp,self.bb,self.bm]=self.mfe() + self.seed=self.hasSeed() + self.au=self.AU_content() + [self.nc,self.pnc]=self.consecutive_pairs() + self.me=self.me_motif() + self.ac=self.acc() + self.np=self.nbp() + self.bl=self.bl() + [self.pe,self.dpse]=self.prThreeEnd() + [self.phys,self.phyf]=self.cv() + + def getFeatures(self): + F=[self.en,self.seed,self.ac,self.au,self.phys,self.phyf,self.me,self.np,self.bl,self.nc,self.pnc,self.pe,self.dpse] + return F + + def mfe(self): + # RNAduplex + t=self.p.split(",") + t=[int(item) for item in t] + seqt=self.m.seq[t[0]:t[1]] + ipp_seq=">"+self.mir.name+"\\n"+self.mir.seq+"\\n"+">"+self.p+"\\n"+seqt + ipp_seq=ipp_seq.encode() + + pp2=subprocess.Popen(["RNAduplex","-e", "5", "-s"],stdout=subprocess.PIPE, stdin=subprocess.PIPE,stderr=subprocess.PIPE) + + # pp2=subprocess.Popen([RNAduplex, "-s"],stdout=subprocess.PIPE, stdin=subprocess.PIPE,stderr=subprocess.PIPE) + out,err=pp2.communicate(input=ipp_seq) + pp2.wait() + out=out.decode() + #pp2.terminate() + lf=[item for item in out.split('\\n') if len(item)>0] + + lf=[item.strip() for item in lf if item[0]!=">"] + + #pdb.set_trace() + lf=lf[0].split() + pm=lf[3].split(',') + pm=[int(item) for item in pm] + pmi=lf[1].split(',') + pmi=[int(item) for item in pmi] + + en=float(lf[-1][1:-1]) + bb=lf[0].split('&')[0] + bm=lf[0].split('&')[1] + ########################### + sd=pmi[0]-2 + msd=pm[1]+sd + #================================================ + bb="."*(pmi[0]-1)+bb+'.'*(len(self.mir.seq)-pmi[1]) + sp=bb[1:7].count('(') + sp1=bb[2:8].count('(') + sp=max(sp,sp1) + #================================================ + pm=[item-1+t[0] for item in pm] + + #en: energy + #sp: # of pairings in the seed region + #bb: pairing details in miRNA + #bm + + return [en,sp,bb,bm] + + def hasSeed(self): + return self.sp/6 + + def AU_content(self): + t=self.p.split(',') + offset=30 # 30 nt + x=8 # seed length + t=[int(item) for item in t] + seed_pos=[max(0,t[1]-1-x-offset),t[1]-1+offset] + #t=[max(0,t[0]-offset),t[1]+offset] + A=[1,1,1,1] + seqt=self.m.seq[seed_pos[0]:seed_pos[1]] + dN={"A":0,"C":1,"G":2,"T":3} + for i in seqt: + if i in dN: + A[dN[i]]+=1 + au=round(float(A[0]+A[3])/sum(A),3) + return au + + def consecutive_pairs(self): + #bm is the pairing of mRNA output from RNAduplex + bm=self.bm + ct=0 + qt=0 + am=2 + A=[] + B=[] + pc=0 + for i in bm: + if i==")": + ct+=1 + qt+=1 + else: + if am<0: + #pdb.set_trace() + B.append([qt,len(bm)-pc]) + qt=0 + am=am-1 + A.append([ct,len(bm)-pc]) + ct=0 + pc+=1 + A.append([ct,len(bm)-pc]) + A=max(A) + return A + + def me_motif(self): + # bb : pairing of miRNA + bb=self.bb + dBP={'(':'m','.':'e'} + bp=[dBP[item] for item in bb] + bp=''.join(bp) + # Averge probability of pairing in each position learned from CLASH + A=[0.464,0.762,0.826,0.954,0.984,0.87,0.824,0.91,0.742,0.776,0.944,0.966,0.784,0.702,0.676,0.558,0.554,0.456,0.562,0.552,0.422,0.096] + dN={'m':0,'e':1} + x=16 + p0=0 + for j in range(x): + ind=dN[bp[j]] + if ind==0: + p=A[j] + else: + p=1-A[j] + p0+=math.log(p) + return p0 + + def acc(self): + t=self.p.split(',') + t=[int(item) for item in t] + return float(self.m.acc[min(max(15,t[1]-1),len(self.m.seq)-1)]) + + def nbp(self): + return self.bb.count('(') + + def bl(self): + return(len(self.bm)) + + def prThreeEnd(self): + pe=self.bb[-8:].count('(') + ps=self.bb[0:8].count('(') + dpse=abs(pe-ps) + return [pe,dpse] + + def cv(self): + t=self.p.split(',') + t=[int(item) for item in t] + lstem=longestStem(self.bb,self.bm) + lstem=[item+t[0] for item in lstem] + try: + phys=self.m.phy[lstem[0]:lstem[1]+1] + phyf1=self.m.phy[max(0,lstem[0]-50):max(0,lstem[0]-10)] + phyf2=self.m.phy[lstem[1]+10:lstem[1]+50] + Avg_phys=sum(phys)/len(phys) + Avg_phyf1=sum(phyf1)/len(phyf1) + Avg_phyf2=sum(phyf2)/len(phyf2) + Avg_phyf=(Avg_phyf1+Avg_phyf2)/2 + return [Avg_phys, Avg_phyf] + except: + return [0,0] + + +#======================================================================= +# these should be in PATH +# RNAduplex="ViennaRNA-2.4.17/src/bin/RNAduplex" +# RNAplfold="ViennaRNA-2.4.17/src/bin/RNAplfold" +# miranda="miRanda-1.9/bin/miranda" + +#======================================================================= +# threading +global_lock = threading.Lock() + + +class thread_counter: + def __init__(self, N): + self.c = 0 + self.N = N + self._lock = threading.Lock() + + def increment(self): + with self._lock: + tmp = self.c + tmp += 1 + time.sleep(0.05) + self.c = tmp + progressbar(self.c. self.N) + + +def write_to_file(file_loc, data): + while global_lock.locked(): + continue + + global_lock.acquire() + + with open(file_loc, "a") as file: + file.write(data) + + global_lock.release() + + +def thread(i, file_loc, mir_info, RR, pb_cut, counter): + # instance of mRNA class + m=mRNA(i[0],i[-1]) + #pdb.set_trace() + out=[] + for j in mir_info: + mir=miRNA(j[0],j[-1]) + ii=Interactions(mir,m) + bs=ii.cand_site() + out_bs=[] + for k in bs: + bijk=binding(mir,m,k) + F=bijk.getFeatures() + FF=np.array(F).reshape(1,-1) + pb=RR.predict_proba(FF)[0][1] + if pb>pb_cut: + out_bs.append([bijk.mir.name,bijk.m.name,k,str(pb)]+[str(item) for item in F]) + out_bs=filterBS(out_bs) + #pdb.set_trace() + out+=out_bs + out=['\\t'.join(item) for item in out] + out='\\n'.join(out) + '\\n' + write_to_file(file_loc=file_loc, data=out) + # inc counter + counter.increment() + + +def main(): + mir_path="${mature}" + mrna_path="${fasta}" + mode_path="${moduleDir}/Human_sklearn_0.22.pkl" + pb_cut=float(0.8) # TODO MALTE + n_threads_input=10 # TODO MALTE + output_file="${meta.id}.bindings.tsv" + + global sessionID + sessionID= 'fn_'+str(uuid.uuid1()) + #======================================================================= + + # read in microRNAs + mir=File(mir_path) + miRNA_info=mir.readSeq() + + # read in mRNA + mRNA_file=File(mrna_path) + mRNA_seq=mRNA_file.readSeq() + + # read in model + f=open(mode_path,'rb') + model=pickle.load(f) + + #======================================================================= + + #pb_cut=0.5 # confidential cut of binding probability + + N=len(mRNA_seq) + + # publish n_threads threads each processing one gene + counter = thread_counter(N) + time_stamp = time.time() + + with concurrent.futures.ThreadPoolExecutor(max_workers=n_threads_input) as executor: + for seq in mRNA_seq: + executor.submit(thread, seq, output_file, miRNA_info, model, pb_cut, counter) + runtime = time.time()-time_stamp + print("runtime: "+ str(runtime)) + print('\\r\\n') + #======================================================================= + # removing temp files + try: + os.remove("%s_dp.ps"%(sessionID)) + os.remove("%s_lunp"%(sessionID)) + os.remove("%s.input"%(sessionID)) + os.remove("%s.out"%(sessionID)) + except: + pass + #============================= + + +if __name__=='__main__': + main() + + # RNAplfold version + process=subprocess.Popen( + ["RNAplfold","-V"], + stdout=subprocess.PIPE, + stdin=subprocess.PIPE, + stderr=subprocess.PIPE + ) + stdout,stderr=process.communicate() + rnaplfold=stdout.decode('utf-8').strip() + rnaplfold_version=rnaplfold.split(" ")[1] + + # RNAduplex version + process=subprocess.Popen( + ["RNAduplex","-V"], + stdout=subprocess.PIPE, + stdin=subprocess.PIPE, + stderr=subprocess.PIPE + ) + stdout,stderr=process.communicate() + rnaduplex=stdout.decode('utf-8').strip() + rnaduplex_version=rnaduplex.split(" ")[1] + + # miranda version + process=subprocess.Popen( + ["miranda","-v"], + stdout=subprocess.PIPE, + stdin=subprocess.PIPE, + stderr=subprocess.PIPE + ) + stdout,stderr=process.communicate() + miranda=stdout.decode('utf-8').strip() + miranda_version=miranda.split("\\n")[1].split(" ")[1] + + # Create version file + versions = { + "${task.process}" : { + "python": platform.python_version(), + "numpy": np.__version__, + "pymysql": pymysql.__version__, + "RNAplfold": rnaplfold_version, + "RNAduplex": rnaduplex_version, + "miranda": miranda_version, + } + } + + with open("versions.yml", "w") as f: + f.write(format_yaml_like(versions)) From 9e9d380f6f33ec0ff2cccb81ee8dfa5d3db5aa14 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:47:15 +0200 Subject: [PATCH 20/53] including tarpmir unification in binding site prediction --- conf/modules.config | 20 +++++++++++++++++++ .../local/mirna/mirna_bindingsites.nf | 15 ++++++++++++++ 2 files changed, 35 insertions(+) diff --git a/conf/modules.config b/conf/modules.config index 5bed5c45..2569eba5 100644 --- a/conf/modules.config +++ b/conf/modules.config @@ -819,6 +819,16 @@ process { ] } + withName: UNIFY_TARPMIR { + ext.args = "-v FS='\\t' -v OFS='\\t' 'NR>1 { split(\$3, arr, \",\"); print \$1, \$2, arr[1], arr[2], \"tarpmir\" }'" + ext.suffix = "tarpmir.tsv" + publishDir = [ + path: { "${params.outdir}/mirna_prediction/binding_sites/tools/tarpmir/unified" }, + mode: params.publish_dir_mode, + saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, + ] + } + withName: COMBINE_BINDINGSITES { ext.prefix = "bindingsites.tsv" } @@ -1042,6 +1052,16 @@ process { ] } + withName: TARPMIR { + ext.prefix = { "${meta.id}.tarpmir" } + publishDir = [ + path: { "${params.outdir}/mirna_prediction/binding_sites/tools/tarpmir/output" }, + mode: params.publish_dir_mode, + saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, + pattern: "*.txt" + ] + } + withName: MIRNA_TARGETS { publishDir = [ path: { "${params.outdir}/mirna_prediction/binding_sites/targets" }, diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index e03bf0b7..e5b905a8 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -3,6 +3,8 @@ include { MIRANDA } from '../../../modules/nf-core/miran include { GAWK as UNIFY_MIRANDA } from '../../../modules/nf-core/gawk' include { TARGETSCAN } from '../../../modules/local/targetscan/predict' include { GAWK as UNIFY_TARGETSCAN } from '../../../modules/nf-core/gawk' +include { TARPMIR } from '../../../modules/local/tarpmir' +include { GAWK as UNIFY_TARPMIR } from '../../../modules/nf-core/gawk' include { MIRNA_TARGETS } from '../../../modules/local/mirna_targets' include { CAT_CAT as COMBINE_BINDINGSITES } from '../../../modules/nf-core/cat/cat' include { MAJORITY_VOTE } from '../../../modules/local/majority_vote' @@ -60,6 +62,19 @@ workflow MIRNA_BINDINGSITES { ch_predictions = ch_predictions.mix(UNIFY_MIRANDA.out.output) } + if (tools_selected.contains('tarpmir')) { + // + // TARPMIR WORKFLOW: + // + + TARPMIR( ch_transcriptome_batches, mirna_fasta.collect() ) + UNIFY_TARPMIR( TARPMIR.out.bindings, [] ) + + ch_versions = ch_versions.mix(TARPMIR.out.versions) + ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) + } + // // CONSOLIDATE PREDICTIONS WORKFLOW: // From c2c64cf5c52a88aa37263adf03ef639ec8c3f25a Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:47:35 +0200 Subject: [PATCH 21/53] adding tarpmir as tool in nf config --- nextflow.config | 3 ++- 1 file changed, 2 insertions(+), 1 deletion(-) diff --git a/nextflow.config b/nextflow.config index 827a58f8..e48c366a 100644 --- a/nextflow.config +++ b/nextflow.config @@ -85,10 +85,11 @@ params { mirna_expression = null mirna_min_reads = 5 mirna_min_sample_percentage = 0.2 - mirna_tools = 'miranda,targetscan' + mirna_tools = 'miranda,targetscan,tarpmir' mirna_tool_filter = 1 mirna_correlation = 'pearson' + //> SPONGE sponge_fdr = 0.01 sponge_cpus = 12 From f3aeba7103e67d0e795f8ac04410532bc6ba4e3a Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sat, 14 Sep 2024 16:48:07 +0200 Subject: [PATCH 22/53] grouping mirna options together --- nextflow_schema.json | 17 +++++++++++++++++ 1 file changed, 17 insertions(+) diff --git a/nextflow_schema.json b/nextflow_schema.json index 83647df9..68ad3992 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -173,6 +173,23 @@ "default": "pearson", "pattern": "^(pearson|spearman)$" }, + "mirna_tools": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "Comma separated list of miRNA bindingsite prediction tools to use. Supported tools: miranda, targetscan.", + "help_text": "Select one or a combination of miRNA bindingsite prediction tools for the pipeline e.g:\n--mirna_tools 'miranda,targetscan'", + "default": "miranda,targetscan,tarpmir", + "pattern": "^((miranda|targetscan|tarpmir)?,?)*[^,]+$" + }, + "mirna_tool_filter": { + "type": "integer", + "fa_icon": "fas fa-intersection", + "description": "Specify the number of votes required for a miRNA to be further considered in downstream analysis.'", + "help_text": "Controls the number of votes required for a binding site prediction to be considered valid. If a miRNA binding site was predicted by two different tools (e.g., miRanda and TargetScan), it receives two votes. By specifying additional tools for miRNA binding site prediction (using the 'mirna_tool_filter' parameter), you can adjust the number of votes required for a binding site to be considered valid.", + "default": 1, + "minimum": 1, + "maximum": 4 + }, "sponge_fdr": { "type": "number", "fa_icon": "fas fa-circle-notch", From 494dca37fdfab3208a28be1dad42ade8ee594c70 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Wed, 25 Sep 2024 10:16:31 +0200 Subject: [PATCH 23/53] fixing python version in majority_vote --- modules/local/majority_vote/templates/majority.py | 2 -- 1 file changed, 2 deletions(-) diff --git a/modules/local/majority_vote/templates/majority.py b/modules/local/majority_vote/templates/majority.py index 4812301a..2869cb37 100644 --- a/modules/local/majority_vote/templates/majority.py +++ b/modules/local/majority_vote/templates/majority.py @@ -1,7 +1,5 @@ #!/usr/bin/env python3 - import platform - import polars as pl import yaml From a7e0655c5586a1ac9c5359981362a485f74a14a7 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:19:34 +0200 Subject: [PATCH 24/53] adding main pita process --- modules/local/pita/main.nf | 34 ++++++++++++++++++++++++++++++++++ 1 file changed, 34 insertions(+) create mode 100644 modules/local/pita/main.nf diff --git a/modules/local/pita/main.nf b/modules/local/pita/main.nf new file mode 100644 index 00000000..f8358d35 --- /dev/null +++ b/modules/local/pita/main.nf @@ -0,0 +1,34 @@ +process PITA { + tag "$meta.id" + label 'process_high' + + conda "${moduleDir}/environment.yml" + container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? + 'https://depot.galaxyproject.org/singularity/ubuntu:20.04' : + 'nf-core/ubuntu:20.04' }" + + input: + tuple val(meta), path(fasta) + tuple val(meta2), path(mature) + + output: + tuple val(meta), path("*_pita_results.tab"), emit: tsv + path "versions.yml" , emit: versions + + when: + task.ext.when == null || task.ext.when + + script: + template "pita_prediction.pl" + + stub: + def prefix = task.ext.prefix ?: "${meta.id}" + + """ + touch ${prefix}.tab + + cat <<-END_VERSIONS > versions.yml + "${task.process}": + END_VERSIONS + """ +} From 41d4413dbebc43e8e1cc4dd2dd036550dfb7a11f Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:19:46 +0200 Subject: [PATCH 25/53] adding adjusted pita template --- .../local/pita/templates/pita_prediction.pl | 136 ++++++++++++++++++ 1 file changed, 136 insertions(+) create mode 100755 modules/local/pita/templates/pita_prediction.pl diff --git a/modules/local/pita/templates/pita_prediction.pl b/modules/local/pita/templates/pita_prediction.pl new file mode 100755 index 00000000..803f8e64 --- /dev/null +++ b/modules/local/pita/templates/pita_prediction.pl @@ -0,0 +1,136 @@ +#!/usr/bin/perl +use File::Basename; +use strict; + +require "${moduleDir}/templates/lib/load_args.pl"; +require "${moduleDir}/templates/lib/format_number.pl"; + +my %args = load_args(\\@ARGV); + +my \$prefix = 'circRNA'; +my \$utr_fn = '${fasta}'; +my \$upstream_fn = get_arg("upstream", "", \\%args); +my \$mir_fn = '${mature}'; +my \$flank_up = get_arg("flank_up", "", \\%args); +my \$flank_down = get_arg("flank_down", "", \\%args); +my \$lengths = '6-8'; +my \$gu = '6;0,7;1,8;1'; +my \$mismatches = '6;0,7;0.8;1'; +my \$loop = get_arg("loop", "", \\%args); +my \$gxp = get_arg("gxp", "", \\%args); + +if (length(\$utr_fn) == 0) +{ + die ("Error: must specifiy a UTR file (-utr)"); +} +if (length(\$mir_fn) == 0) +{ + die ("Error: must specifiy a miRs file (-mir)"); +} +if (length(\$prefix) == 0) +{ + die ("Error: must specifiy a prefix for the output file(s) (-prefix)"); +} + +my \$pid = \$\$; +my \$gxp_header = "\\n\\n\\n\\nUID\\tNAME\\tGWEIGHT\\tE1\\nG2\\tG2\\t1\\t1\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n"; + +print STDERR "Calculating predictions...\\n"; + +my \$runcmd = "${moduleDir}/templates/lib/pita_run.pl -utr \$utr_fn -mir \$mir_fn -prefix \${prefix}_ " . + (length(\$upstream_fn) > 0 ? " -upstream \$upstream_fn" : "") . + (length(\$flank_up) > 0 ? " -flank_up \\"\$flank_up\\"" : "") . + (length(\$flank_down) > 0 ? " -flank_down \\"\$flank_down\\"" : "") . + (length(\$lengths) > 0 ? " -l \\"\$lengths\\"" : "") . + (length(\$gu) > 0 ? " -gu \\"\$gu\\"" : "") . + (length(\$loop) > 0 ? " -loop \\"\$loop\\"" : "") . + (length(\$mismatches) > 0 ? " -m \\"\$mismatches\\"" : ""); + +#print STDERR "Running: \$runcmd\\n"; + +system (\$runcmd); + + +system "rm \${prefix}_ext_utr.stab; mv \${prefix}_pita_results.tab tmp_\${pid}; head -n 1 tmp_\${pid} | cut -f 1-5,8,10- > \${prefix}_pita_results.tab; cat tmp_\${pid} | ${moduleDir}/templates/lib/body.pl 2 -1 | tr -d '\\r' | cut -f 1-8,10- | ${moduleDir}/templates/lib/merge_columns.pl -1 4 -2 5 -d ':' | ${moduleDir}/templates/lib/merge_columns.pl -1 4 -2 5 -d ':' | sed 's/Seed:Mismatchs:G:U/Seed/g' | sort -k 13n >> \${prefix}_pita_results.tab; rm tmp_\${pid};"; + +system "cat \${prefix}_pita_results.tab | ${moduleDir}/templates/lib/body.pl 2 -1 | cut -f 1,2,13 | ${moduleDir}/templates/lib/modify_column.pl -c 2 -m '\\"-1\\"' | ${moduleDir}/templates/lib/average_rows.pl -k 0,1 -losoe -n | ${moduleDir}/templates/lib/cut.pl -f 2,3,1,4 | ${moduleDir}/templates/lib/modify_column.pl -c 3 -m '\\"-1\\"' | ${moduleDir}/templates/lib/modify_column.pl -c 3 -p 2 | sort -k 4n | ${moduleDir}/templates/lib/cap.pl \\"RefSeq,microRNA,Sites,Score\\" > \${prefix}_pita_results_targets.tab"; + +print STDERR "Done.\\n"; + +if (\$gxp == 1) +{ + print STDERR "Creating gxp file...\\n"; + + open (GXP_FILE, ">\${prefix}_pita_results.gxp"); + print GXP_FILE \$gxp_header; + close GXP_FILE; + + system "${moduleDir}/templates/lib/fasta2stab.pl \$utr_fn | ${moduleDir}/templates/lib/stab2length.pl | ${moduleDir}/templates/lib/lin.pl | ${moduleDir}/templates/lib/add_column.pl -s 0 | ${moduleDir}/templates/lib/cut.pl -f 2,1,4,3 | ${moduleDir}/templates/lib/add_column.pl -s 0 | ${moduleDir}/templates/lib/add_column.pl -s 1 | ${moduleDir}/templates/lib/tab2feature_gxt.pl -n 'UTR Sequences' >> \${prefix}_pita_results.gxp"; + system "${moduleDir}/templates/lib/body.pl 2 -1 \${prefix}_pita_results.tab | tr -d '\\r' | ${moduleDir}/templates/lib/cut.pl -f 1-4,2,14 | ${moduleDir}/templates/lib/uniquify.pl -c 1 | ${moduleDir}/templates/lib/tab2feature_gxt.pl -n 'PITA Predictions' -c '0,0,255,1' -lh 50 -l 'Filled box' -minc '0' -maxc '25' >> \${prefix}_pita_results.gxp"; + + + open (GXP_FILE, ">>\${prefix}_pita_results.gxp"); + print GXP_FILE "\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n\\n"; + close GXP_FILE; + + print STDERR "Done.\\n"; +} + +sub removeIllegalXMLChars +{ + my \$str = \$_[0]; + + my \$res_str = ""; + for (my \$i = 0; \$i < length(\$str); \$i++) { + my \$char = substr(\$str, \$i, 1); + if ((ord(\$char) >= 32 and ord(\$char) <= 126) or ord(\$char) == 10 or ord(\$char) == 9) { + \$res_str .= \$char; + } + } + + \$res_str =~ s/\\&/&/g; + \$res_str =~ s/\\"/"/g; + \$res_str =~ s/\\'/'/g; + \$res_str =~ s/\\/>/g; + + return \$res_str; +} + +__DATA__ +syntax: pita_prediction.pl [OPTIONS] + +Execute the PITA algorithm for identifying and scoring microRNA target sites. + +options: + -utr : fasta file containing the UTRs to be scanned + -mir : fasta file containing the microRNA sequences + -upstream : fasta file containing the upstream sequence for each UTR. The IDs + in should match the IDs found int the UTR file. If less 200 bp are + given (or if no file is given), it is padded with Poly-A. + + -flank_up + -flank_down : Flank requirement in basepairs (default: zero for both) + + -ddG_context : Number of bases upstream and downstream for target site that are + taken into account when folding the UTR (default: 70) + + + -prefix : Add the string as a prefix to the output files (pita_results.tab and ext_utr.stab) + -gxp: Produce a gxp (Genomica project file) output file. + + Seed matching parameters: + + -l : Search for seed lengths of num1,...,num2 to the MicroRNA (default: 6-8) + + -gu : Lengths for which G:U wobbles are allowed and number of allowed wobbles. + Format of nums: ,,... (default: 6;0,7;1,8;1) + + -m : Lengths for which mismatches are allowed and number of allowed mismatches + Format of nums: ,,... + (default: 6;0,7;0,8;1) + + -loop : Lengths for which a single loop in either the target or the microrna is allowed + Format of nums: ,,... (default: none) + + From b7c9ea24a039adc1dd67de27918a804225535b94 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:20:46 +0200 Subject: [PATCH 26/53] typo --- modules/local/mirna_targets/main.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/local/mirna_targets/main.nf b/modules/local/mirna_targets/main.nf index e525a9f5..ea931cdd 100644 --- a/modules/local/mirna_targets/main.nf +++ b/modules/local/mirna_targets/main.nf @@ -31,7 +31,7 @@ process MIRNA_TARGETS { bedtools intersect -a targetscan.bed -b miranda.bed | awk '{print \$6}' > mirna_type ## remove duplicate miRNA entries at MRE sites. - ## strategy: sory by circs, sort by start position, sort by site type - the goal is to take the best site type (i.e rank site type found at MRE site). + ## strategy: sort by circs, sort by start position, sort by site type - the goal is to take the best site type (i.e rank site type found at MRE site). paste ${prefix}.mirnas.tmp mirna_type | sort -k3n -k2n -k7r | awk -v OFS="\\t" '{print \$4,\$1,\$2,\$3,\$5,\$6,\$7}' | awk -F "\\t" '{if (!seen[\$1,\$2,\$3,\$4,\$5,\$6]++)print}' | sort -k1,1 -k3n > ${prefix}.mirna_targets.tmp echo -e "circRNA\\tmiRNA\\tStart\\tEnd\\tScore\\tEnergy_KcalMol\\tSite_type" | cat - ${prefix}.mirna_targets.tmp > ${prefix}.mirna_targets.txt From e321dc877c2a303507cf82f66ad0b0630df1c24c Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:21:18 +0200 Subject: [PATCH 27/53] adding config for pita and adjusting config for tarpmir --- conf/modules.config | 12 +++++++++++- 1 file changed, 11 insertions(+), 1 deletion(-) diff --git a/conf/modules.config b/conf/modules.config index 2569eba5..12213309 100644 --- a/conf/modules.config +++ b/conf/modules.config @@ -1058,7 +1058,17 @@ process { path: { "${params.outdir}/mirna_prediction/binding_sites/tools/tarpmir/output" }, mode: params.publish_dir_mode, saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, - pattern: "*.txt" + pattern: "*.bp" + ] + } + + withName: PITA { + ext.prefix = { "${meta.id}.pita" } + publishDir = [ + path: { "${params.outdir}/mirna_prediction/binding_sites/tools/pita/output" }, + mode: params.publish_dir_mode, + saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, + pattern: "*.tab" ] } From d57f23413c8e5cb3ccb8b4c80e76e467c120dac0 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:21:44 +0200 Subject: [PATCH 28/53] adding pita libs and Bin --- .../Bin/ViennaRNA/ViennaRNA-1.6/AUTHORS | 4 + .../Bin/ViennaRNA/ViennaRNA-1.6/COPYING | 19 + .../Bin/ViennaRNA/ViennaRNA-1.6/ChangeLog | 123 + .../ViennaRNA-1.6/Cluster/.deps/AD_main.Po | 1 + .../ViennaRNA-1.6/Cluster/.deps/AS_main.Po | 1 + .../ViennaRNA-1.6/Cluster/.deps/PS3D.Po | 1 + .../ViennaRNA-1.6/Cluster/.deps/cluster.Po | 1 + .../Cluster/.deps/distance_matrix.Po | 1 + .../ViennaRNA-1.6/Cluster/.deps/split.Po | 1 + .../ViennaRNA-1.6/Cluster/.deps/statgeom.Po | 1 + 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modules/local/pita/templates/lib/modify_column.pl create mode 100755 modules/local/pita/templates/lib/pita_run.pl create mode 100755 modules/local/pita/templates/lib/sequence_helpers.pl create mode 100755 modules/local/pita/templates/lib/stab2length.pl create mode 100755 modules/local/pita/templates/lib/system.pl create mode 100755 modules/local/pita/templates/lib/tab2feature_gxt.pl create mode 100755 modules/local/pita/templates/lib/transpose.pl create mode 100755 modules/local/pita/templates/lib/uniquify.pl create mode 100755 modules/local/pita/templates/lib/vector_ops.pl diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/AUTHORS b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/AUTHORS new file mode 100755 index 00000000..a1946e08 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/AUTHORS @@ -0,0 +1,4 @@ +Ivo Hofacker (all parts) +Peter Stadler (design, documentation, cluster algorithms) +Walter Fontana (suboptimal folding, pre-historic implementation of mfe folding) +Stefan Wuchty (suboptimal folding) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/COPYING b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/COPYING new file mode 100755 index 00000000..c3eb63c1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/COPYING @@ -0,0 +1,19 @@ + Disclaimer and Copyright + +The programs, library and source code of the Vienna RNA Package are free +software. They are distributed in the hope that they will be useful +but WITHOUT ANY WARRANTY; without even the implied warranty of +MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +Permission is granted for research, educational, and commercial use +and modification so long as 1) the package and any derived works are not +redistributed for any fee, other than media costs, 2) proper credit is +given to the authors and the Institute for Theoretical Chemistry of the +University of Vienna. + +If you want to include this software in a commercial product, please contact +the authors. + +Note that the file ./lib/naview.c has its own copyright attached. +The ./Readseq/ directory contains a modified version of Don Gilbert's +public domain readseq program. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ChangeLog b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ChangeLog new file mode 100755 index 00000000..e9b9cff8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ChangeLog @@ -0,0 +1,123 @@ +2006-01-18 Ivo Hofacker + + * cleanup berni partition cofold code, including several bug fixes + +2006-01-16 Ivo Hofacker + + * update RNAplfold to working version + * add PS_dot_plot_turn() in PS_dot.c + +2005-11-07 Ivo Hofacker + + * add new utilities colorna and coloraln + +2005-10-11 Christoph Flamm + + * adapt PS_rna_plot() for drawing co-folded structures + +2005-07-24 Ivo Hofacker + + * fix a few memory problems in structure comparison routines + +2005-04-30 Ivo Hofacker + + * add folding of circular RNAs + +2005-03-11 Ivo Hofacker + + * add -mis option to RNAalifold to give "most informative + sequence" as consensus + +2005-02-10 Ivo Hofacker + + * move alifold() into the library + +2004-12-22 Stephan Bernhart + + * add partition function version of RNAcofold + +2004-12-23 Ivo Hofacker + + * add RNApaln for fast structural alignments (RNApdist improvement) + +2004-08-12 Ivo Hofacker + + * fix constrained folding in stochastic backtracking + +2004-07-21 Ivo Hofacker + + * add RNAduplex, to compute hybrid structures without + intra-molecular pairs + +2004-02-09 Ivo Hofacker + + * fix bug in fold that caused segfaults when using Intel compiler + * add computation of ensemble diversity to RNAfold + +2003-09-10 Ivo Hofacker + + * add annotation options to RNAplot + +2003-08-04 Ivo Hofacker + + * stochastic backtracking finally works. Try e.g. + RNAsubopt -p 10 + +2003-07-18 Ivo Hofacker + + * add relplot.pl and rotate_ss.pl utilities for reliability + annotation and rotation of rna structure plots + +2003-01-29 Ivo Hofacker + + * add RNALfold program to compute locally optimal structures with + maximum pair span. + * add RNAcofold for computing hybrid structure + +2002-11-07 Ivo Hofacker + + * change Make_bp_profile() and profile_edit_distance() to use + simple (float *) arrays; makes Perl access much easier. + RNApdist -B now works again + +2002-10-28 Ivo Hofacker + + * Improved Perl module with pod documentation; allow to write + things like + ($structure, $energy) = RNA::fold($seq); + Compatibility warning: the ptrvalue() and related functions are + gone, see the pod documentation for alternatives. + +2002-10-29 Ivo Hofacker + + * added svg structure plots in PS_dot.c and RNAplot + +2002-08-15 Ivo Hofacker + + * Improve reading of clustal files (alifold) + * add a sample alifold.cgi script + +2001-09-18 Ivo Hofacker + + * moved suboptimal folding into the library, thus it's now + accessible from the Perl module + +2001-08-31 Ivo Hofacker + + * added co-folding support in energy_of_struct(), and thus RNAeval + +2001-04-30 Ivo Hofacker + + * switch from handcrafted makefiles to automake and autoconf + +2001-04-05 Ivo Hofacker + + * added PS_rna_plot_a to produce structure plots with annotation + +2001-03-03 Ivo Hofacker + + * add alifold; predict consensus structures from alignment + +2000-09-28 Ivo Hofacker + + * add -d3 option to RNAfold for co-axial stacking diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AD_main.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AD_main.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AD_main.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AS_main.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AS_main.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/AS_main.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/PS3D.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/PS3D.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/PS3D.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/cluster.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/cluster.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/cluster.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/distance_matrix.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/distance_matrix.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/distance_matrix.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/split.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/split.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/split.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/statgeom.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/statgeom.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/statgeom.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/treeplot.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/treeplot.Po new file mode 100755 index 00000000..9ce06a81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/.deps/treeplot.Po @@ -0,0 +1 @@ +# dummy diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AD_main.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AD_main.c new file mode 100755 index 00000000..a5b22f85 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AD_main.c @@ -0,0 +1,85 @@ +#include +#include +#include +#include "split.h" +#include "cluster.h" +#include "distance_matrix.h" +#include "treeplot.h" +#include "utils.h" + + +#define PUBLIC +#define PRIVATE static + +PRIVATE void usage(void); + +main(int argc, char *argv[]) +{ + int i,j; + float **dm; + Split *S; + Union *U; + char type[5]; + + short Do_Split=1, Do_Wards=0, Do_Nj=0; + + for (i=1; i %s\n",type); + + if(Do_Split) { + S = split_decomposition(dm); + sort_Split(S); + print_Split(S); + free_Split(S); + } + if(Do_Wards) { + U = wards_cluster(dm); + + printf_phylogeny(U,"W"); + PSplot_phylogeny(U,"wards.ps","Ward's Method"); + free(U); + } + if(Do_Nj) { + U = neighbour_joining(dm); + printf_phylogeny(U,"Nj"); + PSplot_phylogeny(U,"nj.ps","Neighbor Joining"); + free(U); + } + free_distance_matrix(dm); + } + return 0; +} + + +PRIVATE void usage(void) +{ + nrerror("usage: AnalyseDist [-X[swn]]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AS_main.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AS_main.c new file mode 100755 index 00000000..c516f32c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AS_main.c @@ -0,0 +1,292 @@ +#include +#include +#include "distance_matrix.h" +#include "statgeom.h" +#include "split.h" +#include "cluster.h" +#include "treeplot.h" +#include "utils.h" + + +#define PUBLIC +#define PRIVATE static + +PRIVATE char scale1[] = "....,....1....,....2....,....3....,....4"; +PRIVATE char scale2[] = "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + +main(int argc, char *argv[]) +{ + int n,i,j,l; + int intty; + int outtty; + char *mask, junk[20]; + char **s; + char **ss[4]; + float *B; + float **dm; + Split *S; + Union *U; + char DistAlgorithm='H'; + int nn[4]; + short Do_Split=0, Do_Wards=0, Do_Stg=1, Do_4_Stg=0, Do_Nj=0, Do_Mat=0; + float per_digit, per_gap; + + mask = space(sizeof(char)*54); + strcpy (mask,"%ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz"); + for (i=1; i %s\n","H (Hamming Distance)"); + break; + case 'A' : + dm = StrEdit_SimpleDistMatrix(s,n); + printf("> %s\n","A (Needleman-Wunsch Distance)"); + break; + case 'G' : + dm = StrEdit_GotohDistMatrix(s,n); + printf("> %s\n","G (Gotoh Distance)"); + break; + default: + nrerror("This can't happen."); + } + } + if(Do_Split) { + S = split_decomposition(dm); + sort_Split(S); + print_Split(S); + free_Split(S); + } + if(Do_Wards) { + U = wards_cluster(dm); + printf_phylogeny(U,"W"); + PSplot_phylogeny(U,"wards.ps","Ward's Method"); + free(U); + } + if(Do_Nj) { + U = neighbour_joining(dm); + printf_phylogeny(U,"Nj"); + PSplot_phylogeny(U,"nj.ps","Neighbor Joining"); + free(U); + } + if(Do_Mat) printf_distance_matrix(dm); + } + + if (dm!=NULL) free_distance_matrix(dm); + for(i=0;i Y x [comments] +.br +where 'x' gives the number of taxa, 'Y' is a single character that +indicates the type of distance and 'comment' is an arbitrary comment. +This matches the output format of, e.g., RNAdistance. +The input data file may contain arbitrary lines before and after the +distance matrix. All lines beginning with '> ' that are not of the +above form are written to stdout. The programm continues reading +until it encounters an EOF condition or the terminator character '@'. +.br +A list of taxa names can be specified in the input stream. The list +must begin with a line of the form +.br +* [fname] +.br +if fname is present, it will be used to name the postscript output files. +The entries have the form 'x : Taxon', +where x is the number of taxon, i.e., the corresponding row and column +of the distance matrix. The taxa list need not be complete. It must +end however with a line beginning with '*' or any of the separator +characters. The taxa list is printed on top of the output. + +.SH OPTIONS + +.IP \fB\-X[swn]\fI\fP +specifies the analysis methods to be used. +.IP \fB[s]\fI\fP +Split decomposition. +.IP \fB[w]\fI\fP +Cluster analysis using Ward's method. A PostScript file named '[fname_]wards.ps' +is created containing a drawing of the tree. +.IP \fB[n]\fI\fP +Cluster analysis using Saitou's neighbour joining method. +A PostScript file named '[fname_]nj.ps' is created containing a drawing of the tree. + +.SH REFERENCES + +The method of split decomposition was proposed by H.J. Bandelt and +A.W.M. Dress (Adv Math, 92:1992,47). +.br +The variance method for cluster analysis is due to H.J. Ward. +(J Amer Stat Ass, 58:1963,236). +.br +The neighbour joining method was published by Saitou and Nei +(Mol Biol Evol, 4:1987,406). +.br +This program is part of the Vienna RNA Package. + +.SH WARNING +This a beta test version. + +.SH VERSION +This man page is part of the Vienna RNA Package version 1.2 +.SH AUTHOR +Peter F Stadler and Ivo L Hofacker. +.SH BUGS +Comments should be sent to ivo@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AnalyseSeqs.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AnalyseSeqs.1 new file mode 100755 index 00000000..c5ace8f9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/AnalyseSeqs.1 @@ -0,0 +1,168 @@ +.TH ANALYSESEQS l +.ER +.SH NAME +AnalyseSeqs \- Analyse a set of sequences of common length +.SH SYNOPSIS +\fBAnalyseSeqs [\-X[\fIbswn\fP]] [\-Q] [\-M{mask}[+|!]] [\-D{H|A|G}] [\-d{S|H|D|B}] +.SH DESCRIPTION +.I AnalyseSeqs +reads a set of sequences from stdin and tries a variety of methods +for sequence analysis on them. Currently available are: +.br +Statistical geometry for quadruples of sequences; THIS IS +PRELIMINARY AND NOT WELL TESTED BY NOW. +.br +split decomposition; +neighbour joining and Ward's variance method for reconstructing +phylogenies using various distance measures. +For statistical geometry and the cluster methods PostScript output +is available. +.br +The program continues reading until it encounters one of the +separator characters '@' or '%'. Only sequences of alphabetical +characters or of a specified alphabet are processed, all other +lines are ignored. The program stops reading +if it either encounters an EOF condition, or if there are no +valid sequence data between two lines beginning with separator +characters. +.br +A list of taxa names can be specified in the input stream. The list +begins with a line beginning with '*'. Optionally, a file name prefix +[fn] for the PostScript output can be specified in this line. +The entries have the form 'x : Taxon', +where x is the number of taxon, i.e., of the corresponding entry in +the list of input sequences. The taxa list need not be complete. It must +end, however, with a line beginning with '*' or any of the separator +characters. The taxa list is printed on top of the output. The specified +taxa names are used as labels in the PostScript output. + +.SH OPTIONS +.IP \fB\-X[bswn]\fI\fP +specifies the analysis methods to be used. +.IP \fB[b]\fI\fP +Statistical Geometry. A PostScript file named '[fn_]box.ps' giving a +graphical representation of the statistical geometry is created. The +resulting box is a good measure of 'tree likeness' of the data set. +This is the default. +.IP \fB[s]\fI\fP +Split decomposition. +.IP \fB[w]\fI\fP +Cluster analysis using Ward's method. A PostScript file named '[fn_]wards.ps' +is created containing a drawing of the tree. +.IP \fB[n]\fI\fP +Cluster analysis using Saitou's neighbour joining method. A PostScript +file named '[fn_]nj.ps' is created containing a drawing of the tree. + +.IP \fB\-Q\fB +indicates that a statistical geometry analysis is to be performed +comparing four data sets, for instance to confirm the significance of +a proposed phylogeny. This option is only useful for statistical +geometry analysis and hence the -X option is ignored. Each of the +four data sets must be of the form +.br +* [filename_prefix] +.br +# number +.br +[list of taxa names] +.br +* +.br +list of sequences +.br +% +.br +where number is 1,2,3,4 for the four groups to be compared. + +.IP \fB\-M{mask}[+|!]\fB +allows to specify a mask for the input file. '{mask}' can be one +of the following letters indicating a predefined alphabet or +the %-sign followed by all characters to be accepted. A + sign +at the very end of the mask indicates that the input is to be +handled case sensitive. Default is conversion of the input to +upper case. A ! sign can be used to convert the input data to +RY code: GgAaXx -> R, UuCcKkTt -> Y, all other letters are +converted to *. +.IP \fB-Ma\fI\fP +all letters A-Z and a-z. +.IP \fB-Mu\fI\fP +uppercase letters. +.IP \fB-Ml\fI\fP +lowercase letters. +.IP \fB-Mc\fI\fP +digits [0-9]. +.IP \fB-Mn\fI\fP +all alphanumeric characters. +.IP \fB-MR\fI\fP +RNA alphabet (GCAUgcau). +.IP \fB-MD\fI\fP +DNA alphabet (GCATgcat). +.IP \fB-MA\fI\fP +Amino acids in one-letter code. +.IP \fB-MS\fI\fP +Secondary strcutures coded as '^.()' +.IP \fB-M%alphabet\fI\fP +use the specified alphabet. + +.IP \fB\-D\fB +specifies the algorithm to be used for calculating the +distance matrix of the input data set. Available are +.IP \fB-DH\fI\fP +Hamming Distance +.IP \fB-DA[,cost]\fI\fB +Simple alignment distance according to Needleman and Wunsch. +A gap cost different from 1. can be specified after the comma. +.IP \fB-DG[,cost1,cost2]\fI\fB +Gotoh's distance with gap cost function +g(k) = cost2+cost1*(k-1). cost2<=cost1 has to be fulfilled. +Default values are cost1=1., cost2=1., yielding the same +distance as option A. +.br +ONLY THE HAMMING DISTANCE IS WELL TESTED BY NOW !!! + +.IP \fB\-d\fB +specifies the edit cost matrix to be used. Available are +.IP \fB-dS\fI\fP +simple distance. Indel and substitution of different characters +all have cost 1. The indel cost can be set by specifying the +gap costs with the algorithm options -DA and -DG. This is the +default. +.IP \fB-dH\fI\fP +A distance matrix for RNA secondary structures. Inspired by +Hogeweg's similarity measure (J.Mol.Biol 1988). +Gap-function is set automatically. +.IP \fB-dD\fI\fP +Dayhoff's matrix for amino acid distances. +.IP \fB-dB\fI\fP +Distinguish purines and pyrimidines only. +CAUTION this option of course influences only the calculation of distances. +It does NOT affect computation of the statistical geometry. This is +done directly on the sequences. If you want to do statistical geometry on +RY sequences use the ! sign with the -M option, for instance -MR!. + +.SH REFERENCES +The method of statistical geometry has been introduced by +M. Eigen, R. Winkler-Oswatitsch and A.W.M. Dress +(Proc Natl Acad Sci, 85:1988,5912). +The method of split decomposition was proposed by +H.J. Bandelt and A.W.M. Dress +(Adv Math, 92:1992,47). +The variance method for cluster analysis is due to H.J. Ward +(J Amer Stat Ass, 58:1963,236). +The neighbour joining method was published by Saitou and Nei +(Mol Biol Evol, 4:1987,406). + +This program is part of the Vienna RNA Package + +.SH WARNING +This is the beta test version. Some options or combinations +of options may still produce nonsense. Please send bug reports to +ivo@tbi.univie.ac.at. + +.SH VERSION +This man page is part of the Vienna RNA Package version 1.2. +.SH AUTHOR +Peter F Stadler, Ivo L. Hofacker. +.SH BUGS +Comments should be sent to ivo@itc.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/Makefile new file mode 100755 index 00000000..c8c35bad --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/Makefile @@ -0,0 +1,507 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# Cluster/Makefile. Generated from Makefile.in by configure. + +# Copyright (C) 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, +# 2003, 2004, 2005 Free Software Foundation, Inc. +# This Makefile.in is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + + + + +SOURCES = $(AnalyseDists_SOURCES) $(AnalyseSeqs_SOURCES) + +srcdir = . +top_srcdir = .. + +pkgdatadir = $(datadir)/ViennaRNA +pkglibdir = $(libdir)/ViennaRNA +pkgincludedir = $(includedir)/ViennaRNA +top_builddir = .. +am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd +INSTALL = /usr/bin/install -c +install_sh_DATA = $(install_sh) -c -m 644 +install_sh_PROGRAM = $(install_sh) -c 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/PS3D.c new file mode 100755 index 00000000..7af4de63 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/PS3D.c @@ -0,0 +1,143 @@ +#include +#include +#include "utils.h" + +#define PUBLIC +#define PRIVATE static + +PUBLIC void ps3d_Preambel(FILE *fp, float view[3], float axis[3], char *projtype); +PUBLIC void PS_DrawSimplifiedBox(float X,float Y, float Z, float T, float P, FILE *fp); + + +PUBLIC void ps3d_Preambel(FILE *fp, float view[3], float axis[3], char *projtype) +{ + fprintf(fp,"%%!PS\n"); + fprintf(fp,"%%%%Title: RNA DotPlot\n"); + fprintf(fp,"%%%%Creator: RNAfold V.01.002c - by Oymolon\n"); + fprintf(fp,"%%%%CreationDate: %s", time_stamp()); +/* fprintf(fp,"%%%%BoundingBox: 66 211 518 662\n"); */ + fprintf(fp,"%%%%Pages: 1\n"); + fprintf(fp,"%%%%EndComments: Geil eyh !?\n"); + fprintf(fp,"%%Viewing vector\n"); + fprintf(fp,"/v1 { %f } def\n", view[0]); + fprintf(fp,"/v2 { %f } def\n", view[1]); + fprintf(fp,"/v3 { %f } def\n", view[2]); + fprintf(fp,"/a1 { %f } def\n", axis[0]); + fprintf(fp,"/a2 { %f } def\n", axis[1]); + fprintf(fp,"/a3 { %f } def\n", axis[2]); + fprintf(fp,"%%Define some coefficients for the projections.\n"); + fprintf(fp,"/y1a { v2 a3 mul v3 a2 mul sub } def\n"); + fprintf(fp,"/y2a { v3 a1 mul v1 a3 mul sub } def\n"); + fprintf(fp,"/y3a { v1 a2 mul v2 a1 mul sub } def\n"); + fprintf(fp,"/ya_len { y1a y1a mul y2a y2a mul y3a y3a mul add add sqrt } def\n"); + fprintf(fp,"/x1a { v2 y3a mul v3 y2a mul sub } def\n"); + fprintf(fp,"/x2a { v3 y1a mul v1 y3a mul sub } def\n"); + fprintf(fp,"/x3a { v1 y2a mul v2 y1a mul sub } def\n"); + fprintf(fp,"/xa_len { x1a x1a mul x2a x2a mul x3a x3a mul add add sqrt } def\n"); + fprintf(fp,"/x1 { x1a xa_len div } def\n"); + fprintf(fp,"/x2 { x2a xa_len div } def\n"); + fprintf(fp,"/x3 { x3a xa_len div } def\n"); + fprintf(fp,"/y1 { y1a ya_len div } def\n"); + fprintf(fp,"/y2 { y2a ya_len div } def\n"); + fprintf(fp,"/y3 { y3a ya_len div } def\n"); + fprintf(fp,"/sx { v1 v3 div } def\n"); + fprintf(fp,"/sy { v2 v3 div } def\n"); + fprintf(fp,"/v_len { v1 v1 mul v2 v2 mul v3 v3 mul add add sqrt } def\n"); + fprintf(fp,"/u_len { v1 v1 mul v2 v2 mul add sqrt } def\n"); + fprintf(fp,"/u1 { v2 u_len div } def\n"); + fprintf(fp,"/u2 { v1 neg u_len div } def\n"); + fprintf(fp,"/w1 { v1 v3 mul neg u_len div v_len div } def\n"); + fprintf(fp,"/w2 { v2 v3 mul neg u_len div v_len div } def\n"); + fprintf(fp,"/w3 { v1 v1 mul v2 v2 mul add u_len div v_len div } def\n"); + fprintf(fp,"%%Projection Operators\n"); + fprintf(fp,"%% Projection onto x-y plane in direction v\n"); + fprintf(fp,"/ProjXY { dup sx mul 4 -1 roll exch sub \n"); + fprintf(fp," 3 1 roll sy mul sub \n"); + fprintf(fp," } def \n"); + fprintf(fp,"%% Normal Projection onto a plane normal to (v1,v2,v3!=0)\n"); + fprintf(fp,"/Projnn { w3 mul 3 1 roll dup w2 mul 3 1 roll u2 mul exch \n"); + fprintf(fp," dup w1 mul 3 1 roll u1 mul add 4 1 roll add add \n"); + fprintf(fp," } def \n"); + fprintf(fp,"%% General Normal Projection\n"); + fprintf(fp,"/ProjN { dup y3 mul 4 1 roll x3 mul 3 1 roll dup \n"); + fprintf(fp," y2 mul 5 1 roll x2 mul 3 1 roll dup y1 mul \n"); + fprintf(fp," 6 1 roll x1 mul add add 4 1 roll add add \n"); + fprintf(fp," } def\n"); + fprintf(fp,"/Proj { Proj%s } def\n", projtype); + fprintf(fp,"/L3 { Proj lineto } def\n"); + fprintf(fp,"/RL3 { Proj rlineto } def\n"); + fprintf(fp,"/M3 { Proj moveto } def\n"); + fprintf(fp,"/RM3 { Proj rmoveto } def\n"); + fprintf(fp,"%% end 3D macros\n\n"); +} + +PUBLIC void PS_DrawSimplifiedBox(float X,float Y, float Z, float T, float P, FILE *fp) +{ + float t1, p1, t, lw; + t1 = T/sqrt(2.); + p1 = P/sqrt(3.); + t = X+t1+2*p1; /* approximate size */ + lw = 0.001*t; + fprintf(fp,"/scaling_factor { %f } def \n", 400./t); + fprintf(fp,"%f %f %f Proj \n", X+t1, Y+t1, Z+t1); + fprintf(fp,"scaling_factor mul 2 div 300 sub neg exch \n" ); + fprintf(fp,"scaling_factor mul 2 div 400 sub neg translate \n"); + fprintf(fp,"scaling_factor dup scale\n"); + fprintf(fp,"newpath\n"); + fprintf(fp,"%f setlinewidth\n",lw); + fprintf(fp,"0 0 0 M3\n"); + fprintf(fp,"%f %f %f L3\n", X , 0. , 0. ); + fprintf(fp,"%f %f %f L3\n", X+t1 , t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", X+t1 , Y+t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", t1 , Y+t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", 0. , Y , 0. ); + fprintf(fp,"%f %f %f L3\n", 0. , 0. , 0. ); + fprintf(fp,"%f %f %f L3\n", 0. , 0. , Z ); + fprintf(fp,"%f %f %f L3\n", 0. , t1 , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", 0. , Y+t1 , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", 0. , Y+t1 , t1 ); + fprintf(fp,"%f %f %f L3\n", 0. , Y , 0. ); + fprintf(fp,"%f %f %f L3\n", 0. , 0. , 0. ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", t1 , Y+t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", 0. , Y+t1 , t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", X+t1 , 0. , t1 ); + fprintf(fp,"%f %f %f L3\n", X+t1 , 0. , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", X+t1 , Y , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", X+t1 , Y+t1 , Z ); + fprintf(fp,"%f %f %f L3\n", X+t1 , Y+t1 , 0. ); + fprintf(fp,"%f %f %f L3\n", X+t1 , t1 , 0. ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , 0. , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", t1 , 0. , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", 0. , t1 , Z+t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , Y , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", X , Y+t1 , Z+t1 ); + fprintf(fp,"%f %f %f L3\n", 0. , Y+t1 , Z+t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X , 0. , 0. ); + fprintf(fp,"%f %f %f L3\n", X+t1 , 0. , t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", 0. , 0. , Z ); + fprintf(fp,"%f %f %f L3\n", t1 , 0. , Z+t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , Y+t1 , Z ); + fprintf(fp,"%f %f %f L3\n", X , Y+t1 , Z+t1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", 0. , 0. , 0. ); + fprintf(fp,"%f %f %f RL3\n", -p1 , -p1 , -p1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , Y+t1 , 0. ); + fprintf(fp,"%f %f %f RL3\n", p1 , p1 , -p1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", X+t1 , 0. , Z+t1 ); + fprintf(fp,"%f %f %f RL3\n", p1 , -p1 , p1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"%f %f %f M3\n", 0. , Y+t1 , Z+t1 ); + fprintf(fp,"%f %f %f RL3\n", -p1 , p1 , p1 ); + fprintf(fp,"stroke\n"); + fprintf(fp,"showpage\n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/PS3D.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/PS3D.h new file mode 100755 index 00000000..842e5901 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/PS3D.h @@ -0,0 +1,2 @@ +extern void ps3d_Preambel(FILE *fp, float view[3], float axis[3], char *projtype); +extern void PS_DrawSimplifiedBox(float X,float Y, float Z, float T, float P, FILE *fp); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/StrEdit_CostMatrix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/StrEdit_CostMatrix.h new file mode 100755 index 00000000..25e45ad6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/StrEdit_CostMatrix.h @@ -0,0 +1,107 @@ +#define DINF 100000.0 +#define GAP 1.0 + +/* -------------------------------------------------------------------------- */ + +/* BinCode: 'B' ... RNA sequences, but RY-distance only */ + +char StrEdit_BinCodeA[6] = "_GCAU"; +/* _ G C A U */ +float StrEdit_BinCodeM[5][5] = + { { 5., 1., 1., 1., 1. }, /* _ */ + { 1., 0., 1., 0., 1. }, /* G */ + { 1., 1., 0., 1., 0. }, /* C */ + { 1., 0., 1., 0., 1. }, /* A */ + { 1., 1., 0., 1., 0. } }; /* U */ + +/* -------------------------------------------------------------------------- */ + +/* Dayhoff: 'D' ... Dayhoff's matrix for Amino Acids */ +/* CAUTION THIS IS A SIMILARITY MATRIX !!! */ + +char StrEdit_DayhoffA[22] = +"_CSTPAGNDEQHRKMILVFYW"; +float StrEdit_DayhoffM[21][21] = +/* _ C S T P A G N D E Q H R K M I L V F Y W */ + {{21.,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP}, /* _ ... < ~gap~ > */ + {GAP,12., 0.,-2.,-3.,-2.,-3.,-4.,-5.,-5.,-5.,-3.,-4.,-5.,-5.,-2.,-6.,-2.,-4., 0.,-8.}, /* C ... Cysteine */ + {GAP, 0., 2., 1., 1., 1., 1., 1., 0., 0.,-1.,-1., 0., 0.,-2.,-1.,-3.,-1.,-3.,-3.,-2.}, /* S ... Serine */ + {GAP,-2., 1., 3., 0., 1., 0., 0., 0., 0.,-1.,-1.,-1., 0.,-1., 0.,-2., 0.,-3.,-3.,-5.}, /* T ... Threonine */ + {GAP,-3., 1., 0., 6., 1.,-1.,-1.,-1.,-1., 0., 0., 0.,-1.,-2.,-2.,-3.,-1.,-5.,-5.,-6.}, /* P ... Proline */ + {GAP,-2., 1., 1., 1., 2., 1., 0., 0., 0., 0.,-1.,-2.,-1.,-1.,-1.,-2., 0.,-4.,-3.,-6.}, /* A ... Alanine */ + {GAP,-3., 1., 0.,-1., 1., 5., 0., 1., 0.,-1.,-2.,-3.,-2.,-3.,-3.,-4.,-1.,-5.,-5.,-7.}, /* G ... Glycine */ + {GAP,-4., 1., 0.,-1., 0., 0., 2., 2., 2., 1., 2., 0., 1.,-2.,-2.,-3.,-2.,-4.,-2.,-4.}, /* N ... Asparagine */ + {GAP,-5., 0., 0.,-1., 0., 1., 2., 4., 3., 2., 1.,-1., 0.,-3.,-2.,-4.,-2.,-6.,-4.,-7.}, /* D ... Aspartic A */ + {GAP,-5., 0., 0.,-1., 0., 0., 1., 3., 4., 2., 1.,-1., 0.,-2.,-2.,-3.,-2.,-5.,-4.,-7.}, /* E ... Glutamic A */ + {GAP,-5.,-1.,-1., 0., 0.,-1., 1., 2., 2., 4., 3., 3., 1.,-1.,-2.,-2.,-2.,-5.,-4.,-5.}, /* Q ... Glutamine */ + {GAP,-3.,-1.,-1., 0.,-1.,-2., 2., 1., 1., 3., 6., 2., 0.,-2.,-2.,-2.,-2.,-2., 0.,-3.}, /* H ... Histidine */ + {GAP,-4., 0.,-1., 0.,-2.,-3., 0.,-1.,-1., 1., 2., 6., 3., 0.,-2.,-3.,-2.,-4.,-4.,-2.}, /* R ... Arginine */ + {GAP,-5., 0., 0.,-1.,-1.,-2., 1., 0., 0., 1., 0., 2., 5., 0.,-2.,-3.,-2.,-5.,-4.,-3.}, /* K ... Lysine */ + {GAP,-5.,-2.,-1.,-2.,-1.,-3.,-2.,-3.,-2.,-1.,-2., 0., 0., 6., 2., 4., 2., 0.,-2.,-4.}, /* M ... Methionine */ + {GAP,-2.,-1., 0.,-2.,-1.,-3.,-2.,-2.,-2.,-2.,-2.,-2.,-2., 2., 5., 2., 4., 1.,-1.,-5.}, /* I ... Isoleucine */ + {GAP,-6.,-3.,-2.,-3.,-2.,-4.,-3.,-4.,-3.,-2.,-2.,-3.,-3., 4., 2., 6., 2., 2.,-1.,-2.}, /* L ... Leucine */ + {GAP,-2.,-1., 0.,-1., 0.,-1.,-2.,-2.,-2.,-2.,-2.,-2.,-2., 2., 4., 2., 4.,-1.,-2.,-6.}, /* V ... Valine */ + {GAP,-4.,-3.,-3.,-5.,-4.,-5.,-4.,-6.,-5.,-5.,-2.,-4.,-5., 0., 1., 2.,-1., 9., 7., 0.}, /* F ... Phenylalanine */ + {GAP, 0.,-3.,-3.,-5.,-3.,-5.,-2.,-4.,-4.,-4., 0.,-4.,-4.,-2.,-1.,-1.,-2., 7.,10., 0.}, /* Y ... Tyrosine */ + {GAP,-8.,-2.,-5.,-6.,-6.,-7.,-4.,-7.,-7.,-5.,-3.,-2.,-2.,-4.,-5.,-2.,-6., 0., 0.,17.}}; /* W ... Tryptophane */ + +/* -------------------------------------------------------------------------- */ + +/* Hogeweg: 'H' ... Hogeweg's matrix for String Edit of Secondary Structures */ + +char StrEdit_HogewegA[6]="_.^()"; +float StrEdit_HogewegM[5][5] = +/* _ . ^ ( ) */ + { { 5., GAP, GAP, GAP, GAP }, /* _ ... */ + { GAP, 0., 1., 1., 1. }, /* . ... unpaired */ + { GAP, 1., 0., 1., 1. }, /* ^ ... hairpin-unpaired */ + { GAP, 1., 1., 0., DINF }, /* ( ... paired upstream */ + { GAP, 1., 1., DINF, 0. } }; /* ) ... paired downstream */ + +/* -------------------------------------------------------------------------- */ + +char StrEdit_GLHA[22] = "_ACDEFGHIKLMNPQRSTVWY"; +float StrEdit_GLHM[21][21] = { + {21.,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP,GAP}, + {GAP, 0.000, .156, .150, .148, .730, .045, .455, .346, .193, .335, + 1.018, .140, .058, .237, .308, .046, .010, .246, .124, .977}, /* ALA */ + {GAP, .156, 0.000, .219, .206, .779, .188, .412, .389, .150, .318, + .870, .183, .198, .225, .256, .149, .149, .289, .073, .940}, /* CYS */ + {GAP, .150, .219,0.000, .017, .840, .120, .337, .494, .129, .479, + 1.071, .047, .114, .122, .206, .108, .157, .395, .194, .963}, /* ASP */ + {GAP, .148, .206, .017,0.000, .836, .122, .328, .493, .114, .473, + 1.057, .030, .117, .110, .194, .103, .154, .393, .181, .950}, /* GLU */ + {GAP, .730, .779, .840, .836,0.000, .753,1.036, .595, .864, .586, + 1.301, .822, .763, .900, .957, .761, .729, .617, .726, .920}, /* PHE */ + {GAP, .045, .188, .120, .122, .753,0.000, .444, .376, .193, .377, + 1.055, .124, .014, .224, .302, .046, .054, .279, .157, .989}, /* GLY */ + {GAP, .455, .412, .337, .328,1.036, .444,0.000, .785, .279, .718, + 1.044, .321, .442, .225, .171, .411, .459, .682, .404, .824}, /* HIS */ + {GAP, .346, .389, .494, .493, .595, .376, .785,0.000, .513, .159, + 1.006, .485, .385, .575, .631, .391, .340, .103, .385,1.143}, /* ILE */ + {GAP, .193, .150, .129, .114, .864, .193, .279, .513,0.000, .461, + .954, .093, .194, .077, .119, .152, .193, .410, .152, .919}, /* LYS */ + {GAP, .335, .318, .479, .473, .586, .377, .718, .159, .461,0.000, + .872, .456, .389, .530, .571, .372, .327, .142, .319,1.035}, /* LEU */ + {GAP, 1.018, .870,1.071,1.057,1.301,1.055,1.044,1.006, .954, .872, + 0.000,1.033,1.065,1.013, .966,1.018,1.010, .977, .921,1.282}, /* MET */ + {GAP, .140, .183, .047, .030, .822, .124, .321, .485, .093, .456, + 1.033,0.000, .122, .102, .184, .095, .146, .383, .156, .930}, /* ASN */ + {GAP, .058, .198, .114, .117, .763, .014, .442, .385, .194, .389, + 1.065, .122,0.000, .222, .301, .054, .067, .289, .168, .996}, /* PRO */ + {GAP, .237, .225, .122, .110, .900, .224, .225, .575, .077, .530, + 1.013, .102, .222,0.000, .086, .192, .241, .472, .216, .910}, /* GLN */ + {GAP, .308, .256, .206, .194, .957, .302, .171, .631, .119, .571, + .966, .184, .301, .086,0.000, .265, .310, .528, .261, .901}, /* ARG */ + {GAP, .046, .149, .108, .103, .761, .046, .411, .391, .152, .372, + 1.018, .095, .054, .192, .265,0.000, .051, .289, .117, .963}, /* SER */ + {GAP, .010, .149, .157, .154, .729, .054, .459, .340, .193, .327, + 1.010, .146, .067, .241, .310, .051,0.000, .239, .119, .979}, /* THR */ + {GAP, .246, .289, .395, .393, .617, .279, .682, .103, .410, .142, + .977, .383, .289, .472, .528, .289, .239,0.000, .282,1.076}, /* VAL */ + {GAP, .124, .073, .194, .181, .726, .157, .404, .385, .152, .319, + .921, .156, .168, .216, .261, .117, .119, .282,0.000, .893}, /* TRP */ + {GAP, .977, .940, .963, .950, .920, .989, .824,1.143, .919,1.035, + 1.282, .930, .996, .910, .901, .963, .979,1.076, .893,0.000}, /* TYR */ +}; + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/cluster.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/cluster.c new file mode 100755 index 00000000..3cf75403 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/cluster.c @@ -0,0 +1,281 @@ +/* Last changed Time-stamp: <95/07/12 19:52:41 ivo> */ +/* + Cluster Analysis using Ward's Method + Ward J Amer Stat Ass, 58 (1963), p236 + c Peter Stadler and Ivo Hofacker +*/ +#include +#include +#include +#include "utils.h" + +#define PUBLIC +#define PRIVATE static + +#define INFINITY 1000000 + +typedef struct{ + int set1; + int set2; + float distance; + float distance2; + } Union; + +typedef struct { + int type; + int weight; + int father; + int sons; + int leftmostleaf; + } Postorder_list; + +PUBLIC Union *wards_cluster(float **clmat); +PUBLIC Union *neighbour_joining(float **clmat); +PUBLIC void printf_phylogeny(Union *tree, char *type); + + +/*--------------------------------------------------------------------*/ + +PUBLIC Union *wards_cluster(float **clmat) +{ + float **d; + int *indic; + int *size; + float *help; + Union *tree; + + float min,deno,xa,xb,x; + int i,j,step,s=0,t=0,n; + + n= (int)(clmat[0][0]); + + size = (int *) space((n+1)*sizeof(int)); + d = (float **) space((n+1)*sizeof(float *)); + for(i=0;i<=n;i++) + d[i] = (float *) space((n+1)*sizeof(float)); + indic = (int *) space((n+1)*sizeof(int)); + help = (float *) space((n+1)*sizeof(float)); + tree = (Union *) space((n+1)*sizeof(Union)); + + tree[0].set1 = n; + tree[0].set2 = 0; + tree[0].distance = 0.0; + tree[0].distance2 = 0.0; + + for (i=1;i<=n;i++) size[i]=1; + for (i=1; i<=n; i++){ + for(j=1; j<=n; j++){ + d[i][j] = clmat[i][j]; + } + } + + /* look for the indices [s,t] with minimum d[s][t]*/ + for(step=1;step %d %s ( Phylogeny using ",n, type); + switch(type[0]){ + case 'W' : + printf("Ward's Method )\n"); + printf("> Nodes Variance\n"); + for(i=1; i Nodes Branch Length in Tree\n"); + for(i=1; i +#include +#include +#include +#include "utils.h" +#include "StrEdit_CostMatrix.h" + +#define PUBLIC +#define PRIVATE static +#define MAXSEQS 1000 +#define MIN(A, B) ((A) < (B) ? (A) : (B)) +#define MIN3(A,B,C) (MIN((MIN((A),(B))),(C))) +#define MAX(A, B) ((A) > (B) ? (A) : (B)) + +PUBLIC float **read_distance_matrix(char type[]); +PUBLIC char **read_sequence_list(int *n_of_seqs, char *mask); +PUBLIC float **Hamming_Distance_Matrix(char **seqs, int n_of_seqs); +PUBLIC float **StrEdit_SimpleDistMatrix(char **seqs, int n_of_seqs); +PUBLIC float **StrEdit_GotohDistMatrix(char **seqs, int n_of_seqs); +PUBLIC void free_distance_matrix(float **x); +PUBLIC void printf_distance_matrix(float **x); +PUBLIC void printf_taxa_list(void); +PUBLIC char *get_taxon_label(int whoami); +PUBLIC float StrEdit_SimpleDist(char *str1, char *str2); +PUBLIC float StrEdit_GotohDist(char *str1, char *str2); +PUBLIC void Set_StrEdit_CostMatrix(char type); +PUBLIC void Set_StrEdit_GapCosts(float per_digit, float per_gap); + +/* NOTE: x[0][0] = (float)size_of_matrix; */ + +PRIVATE void read_taxa_list(void); +PRIVATE int string_consists_of(char line[],char *mask); +PRIVATE float StrEditCost( int i, int j, char *T1, char *T2); +PRIVATE int decode(char id); + +PRIVATE char Taxa_List[MAXSEQS][50]; +PRIVATE int Taxa_Numbers[MAXSEQS]; +PRIVATE int N_of_named_taxa=0; +PRIVATE char *file_name; +PRIVATE char N_of_infiles=0; +PRIVATE float **StrEdit_CostMatrix; +PRIVATE char *StrEdit_ValidAlphabet; +PRIVATE float StrEdit_GapCost = 1.; +PRIVATE float StrEdit_GotohAlpha = 1.; +PRIVATE float StrEdit_GotohBeta = 1.; + + + +PUBLIC float **read_distance_matrix(char type[]) +{ + char *line; + float **D; + float tmp; + int i,j,size; + + while(1) { + type[0]= '\0'; + size = 0; + D = NULL; + if ((line = get_line(stdin))==NULL) return NULL; + if (*line =='@') return NULL; + if (*line =='*') { + N_of_infiles++; + if(file_name) free(file_name); + + if(strlen(line)>1) { + file_name = (char *) space(sizeof(char)*strlen(line)); + sscanf(line,"*%s",file_name); + } else { + file_name = (char *) space(10); + sprintf(file_name,"%d",N_of_infiles); + } + read_taxa_list(); + } + else if (*line=='>') { + int r; + size = 0; + r = sscanf(line,"> %1s%*[ ] %d", type, &size); + fprintf(stderr, "%d ", r); + if (r==EOF) return NULL; + if((r==2)&&(size>1)) { + D=(float **)space((size+1)*sizeof(float *)); + for(i=0; i<=size; i++) + D[i] = (float *)space((size+1)*sizeof(float)); + D[0][0] = (float)size; + D[1][1] = 0.0; + for(i=2; i<= size; i++) { + D[i][i] = 0.0; + for(j=1; j1) { + file_name = (char *) space(sizeof(char)*strlen(line)); + sscanf(line,"*%s",file_name); + } else { + file_name = (char *) space(10); + sprintf(file_name,"%d",N_of_infiles); + } + read_taxa_list(); + free(line); + continue; + } + + len = strlen(line); + if(string_consists_of(line,mask)){ + if(mask[0]=='%') { + for(i=0;i false */ + return 1; /* loop left after last char -> true */ +} +/* -------------------------------------------------------------------------- */ + +PUBLIC void free_distance_matrix(float **x) +{ + int i,n; + n=(int) x[0][0]; + for(i=0;i<=n;i++) free(x[i]); + free(x); + x=NULL; +} + +/* -------------------------------------------------------------------------- */ + +PUBLIC void printf_distance_matrix(float **x) +{ + int i,j,n; + n=(int) x[0][0]; + printf("> X %d\n",n); + if(n>1){ + for(i=2;i<=n;i++) { + for(j=1;j0){ + printf("* List of Taxa: %s\n", file_name); + for(i=0;i0) i1 = decode(T1[i-1]); else i1 = 0; + if(j>0) j1 = decode(T2[j-1]); else j1 = 0; + if(StrEdit_CostMatrix==NULL) { + if(i&&j) return (float)(i1!=j1); + else return (float) StrEdit_GapCost; + } + else return (float) StrEdit_CostMatrix[i1][j1]; +} + +/* -------------------------------------------------------------------------- */ + +PRIVATE int decode(char id) +{ + int n,alen; + + if (!StrEdit_ValidAlphabet) return (int)id; + alen = strlen(StrEdit_ValidAlphabet); + if(!alen) return (int)id; + + for(n=0;n set to ~gap~\n"); + return 0; +} + +/* -------------------------------------------------------------------------- */ + +PUBLIC void Set_StrEdit_CostMatrix(char type) +{ + int i,j; + if(StrEdit_ValidAlphabet) { + free(StrEdit_ValidAlphabet); + StrEdit_ValidAlphabet = NULL; + } + if(StrEdit_CostMatrix) { + free(StrEdit_CostMatrix); + StrEdit_CostMatrix = NULL; + } + switch(type){ + case 'D' : + StrEdit_ValidAlphabet = (char*) space((20+2)*sizeof(char)); + strcpy(StrEdit_ValidAlphabet,StrEdit_DayhoffA); + StrEdit_CostMatrix = (float**) space((20+1)*sizeof(float*)); + for(i=0;i<=20;i++) + StrEdit_CostMatrix[i] = (float*)space((20+1)*sizeof(float)); + for(i=1;i<=20;i++) { + for(j=1;j<=20;j++) { + StrEdit_CostMatrix[i][j] = + MAX(StrEdit_DayhoffM[i][i],StrEdit_DayhoffM[j][j])- + StrEdit_DayhoffM[i][j]; + } + StrEdit_CostMatrix[i][0] = StrEdit_DayhoffM[i][i]; + StrEdit_CostMatrix[0][i] = StrEdit_DayhoffM[i][i]; + } + StrEdit_CostMatrix[0][0] = StrEdit_DayhoffM[0][0]; + break; + case 'A' : + StrEdit_ValidAlphabet = (char*) space((20+2)*sizeof(char)); + strcpy(StrEdit_ValidAlphabet,StrEdit_GLHA); + StrEdit_CostMatrix = (float**) space((20+1)*sizeof(float*)); + for(i=0;i<=20;i++) + StrEdit_CostMatrix[i] = (float*)space((20+1)*sizeof(float)); + for(i=1;i<=20;i++) { + for(j=1;j<=20;j++) + StrEdit_CostMatrix[i][j] = StrEdit_GLHM[i][j]; + StrEdit_CostMatrix[i][0] = StrEdit_CostMatrix[0][i] = + StrEdit_GapCost; + } + StrEdit_CostMatrix[0][0] = StrEdit_GLHM[0][0]; + break; + case 'B' : + StrEdit_ValidAlphabet = space((4+2)*sizeof(char)); + strcpy(StrEdit_ValidAlphabet,StrEdit_BinCodeA); + StrEdit_CostMatrix = (float**) space((4+1)*sizeof(float*)); + for(i=0;i<=4;i++) + StrEdit_CostMatrix[i] = (float*)space((4+1)*sizeof(float)); + for(i=0;i<=4;i++) + for(j=0;j<=4;j++) + StrEdit_CostMatrix[i][j] = StrEdit_BinCodeM[i][j]; + break; + case 'H' : + StrEdit_ValidAlphabet = space((4+2)*sizeof(char)); + strcpy(StrEdit_ValidAlphabet,StrEdit_HogewegA); + StrEdit_CostMatrix = (float**) space((4+1)*sizeof(float*)); + for(i=0;i<=4;i++) + StrEdit_CostMatrix[i] = (float*)space((4+1)*sizeof(float)); + for(i=0;i<=4;i++) + for(j=0;j<=4;j++) + StrEdit_CostMatrix[i][j] = StrEdit_HogewegM[i][j]; + StrEdit_GotohAlpha = 3.; + StrEdit_GotohBeta = 0.; + break; + default: + if(!StrEdit_GapCost) StrEdit_GapCost = 1.; /* This is the simple distance */ + } +} + +/* -------------------------------------------------------------------------- */ + +PUBLIC void Set_StrEdit_GapCosts(float per_digit, float per_gap) +{ + if(per_gap==0.) per_gap = per_digit; + if(per_digit<0) nrerror("Gap Costs invalid."); + if(per_digit>per_gap) nrerror("Gap Costs invalid."); + + StrEdit_GapCost = per_digit; + StrEdit_GotohAlpha = per_digit; /* Gotoh gap function g(k) = a + b(k-1) */ + StrEdit_GotohBeta = per_gap; + +} + +/* -------------------------------------------------------------------------- */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/distance_matrix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/distance_matrix.h new file mode 100755 index 00000000..896598c7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/distance_matrix.h @@ -0,0 +1,14 @@ +extern float **read_distance_matrix(char type[]); +extern char **read_sequence_list(int *n_of_seqs,char *mask); +extern float **Hamming_Distance_Matrix(char **seqs, int n_of_seqs); +extern float **StrEdit_SimpleDistMatrix(char **seqs, int n_of_seqs); +extern float **StrEdit_GotohDistMatrix(char **seqs, int n_of_seqs); +extern char *get_taxon_label(int whoami); +extern void free_distance_matrix(float **x); +extern void printf_distance_matrix(float **x); +extern void printf_taxa_list(void); +extern float StrEdit_SimpleDist(char *str1, char *str2); +extern float StrEdit_GotohDist(char *str1, char *str2); +extern void Set_StrEdit_CostMatrix(char type); +extern void Set_StrEdit_GapCosts(float per_digit, float per_gap); + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.c new file mode 100755 index 00000000..7d2d77de --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.c @@ -0,0 +1,332 @@ +/* Last changed Time-stamp: <95/07/12 19:49:53 ivo>*/ +/* + Split Decomposition of Distance Matrices + as described by H.J.Bandelt and A.W.M.Dress + Adv Math, 92 (1992) p47 + c Peter Stadler and Ivo L. Hofacker +*/ +#include +#include +#include +#include "utils.h" + +#define PUBLIC +#define PRIVATE static +#define DEBUG 0 +#define SHORT_OUTPUT 1 + +#define DINFTY 1.e32 +#define ZERO 1.e-10 + + +typedef struct { + short *splitlist[2]; + int splitsize; + double isolation_index; } Split; + +PUBLIC Split *split_decomposition(float **dist); +PUBLIC void free_Split(Split *x); +PUBLIC void print_Split(Split *x); +PUBLIC void sort_Split(Split *x); + +PUBLIC Split *split_decomposition(float **dist) +{ + + int elm, n_of_splits; + short *full_slots; + int i,j,sp,new_sp,spp; + int i2,j1,j2,maxlen; + int x,y,z; + double alpha,beta,tmp; + double test1,test2; + Split *SD, *S; + int number_of_points; + + number_of_points = (int) dist[0][0]; + + /* Initialize */ + elm = 2; + n_of_splits = 1; + maxlen = (number_of_points+1)*(number_of_points+1); + full_slots = (short *) space(2*(maxlen+1)*sizeof(short)); + full_slots[1]=1; + + SD = space((maxlen+1)*sizeof(Split)); + + SD[0].splitlist[0] = NULL; + SD[0].splitlist[1] = NULL; + SD[0].splitsize = 1; + SD[0].isolation_index = 0.0; + /**/ + SD[1].splitlist[0] = (short *) space((number_of_points+1)*sizeof(short)); + SD[1].splitlist[0][0] = number_of_points; + SD[1].splitlist[0][1] = 1; + SD[1].splitlist[1] = (short *) space((number_of_points+1)*sizeof(short)); + SD[1].splitlist[1][1] = 2; + SD[1].splitsize = 1; + SD[1].isolation_index = dist[1][2]; + + + /* Iteration */ + + for( elm=3; elm <= number_of_points; elm++){ + + for (sp=1, spp=n_of_splits;sp<=n_of_splits; sp++){ + + SD[sp].splitlist[0][0] = elm; + + /* 1. Split = {old_A | old_B+{elm}} */ + + alpha = 2.0*SD[sp].isolation_index; + for(i2=1; i2<=(elm - SD[sp].splitsize); i2++){ + if(i2==(elm-SD[sp].splitsize)) { + x = elm; + } + else{ + x= SD[sp].splitlist[1][i2]; + } + for(j1=1; j1 <= SD[sp].splitsize; j1++){ + y= SD[sp].splitlist[0][j1]; + for(j2=1; j2 <= (SD[sp].splitsize); j2++){ + z= SD[sp].splitlist[0][j2]; + + /* calculate the value beta = beta(elm,x; y,z) */ + + beta = dist[elm][y] + dist[x][z]; + tmp = dist[elm][z] + dist[x][y]; + if(tmp>beta) beta=tmp; + tmp = dist[elm][x] + dist[y][z]; + if(tmp>beta) beta=tmp; + beta -= ( dist[elm][x] + dist[y][z] ); + + if(beta ZERO){ + /* add {old_A | old_B + {elm}} to the split-list */ + spp++; + full_slots[spp] =1; + SD[spp].splitsize = SD[sp].splitsize; + SD[spp].isolation_index = alpha; + SD[spp].splitlist[0] = (short *) space((number_of_points+1)*sizeof(short)); + SD[spp].splitlist[0][0] = elm; + SD[spp].splitlist[1] = (short *) space((number_of_points+1)*sizeof(short)); + for(i=1; i<=SD[spp].splitsize; i++) + SD[spp].splitlist[0][i] = SD[sp].splitlist[0][i]; + for(i=1; i<=(elm-1-SD[spp].splitsize); i++) + SD[spp].splitlist[1][i] = SD[sp].splitlist[1][i]; + SD[spp].splitlist[1][elm-SD[spp].splitsize] = elm; + } + + /* 2. Split = {old_A+{elm} | old_B} */ + + alpha = 2.0*SD[sp].isolation_index; + for(i2=1; i2<= (SD[sp].splitsize+1); i2++){ + if(i2==(SD[sp].splitsize+1)){ + x= elm; + } + else + { + x= SD[sp].splitlist[0][i2]; + } + for(j1=1; j1 <= (elm-1-SD[sp].splitsize); j1++){ + y= SD[sp].splitlist[1][j1]; + for(j2=1; j2 <= (elm-1-SD[sp].splitsize); j2++){ + z= SD[sp].splitlist[1][j2]; + + /* calculate the value beta = beta(elm,x; y,z) */ + + beta = dist[elm][y] + dist[x][z]; + tmp = dist[elm][z] + dist[x][y]; + if(tmp>beta) beta=tmp; + tmp = dist[elm][x] + dist[y][z]; + if(tmp>beta) beta=tmp; + beta -= ( dist[elm][x] + dist[y][z] ); + + if(beta ZERO){ + /* replace {old_A | old_B} by {old_A+{elm} | old_B} in the splitlist */ + SD[sp].splitsize++; + SD[sp].splitlist[0][SD[sp].splitsize] = elm; + SD[sp].isolation_index = alpha; + } + else{ + /* remove {old_A | old_B} from the split list */ + full_slots[sp] = 0; + free(SD[sp].splitlist[0]); + SD[sp].splitlist[0] = NULL; + free(SD[sp].splitlist[1]); + SD[sp].splitlist[1] = NULL; + SD[sp].splitsize = 0; + SD[sp].isolation_index = 0.0; + } + } + + /* 3. Split = { {elm} | {1,...,elm-1} } */ + + alpha=DINFTY; + for(i=1;i<=elm-1;i++){ + for(j=1; j<=elm-1;j++){ + tmp = dist[elm][i]+dist[elm][j] - dist[i][j]; + if( tmp < alpha) alpha = tmp; + } + } + alpha/=2.; + if (alpha > ZERO){ + spp++; + full_slots[spp] = 1; + SD[spp].splitsize = 1; + SD[spp].isolation_index = alpha; + SD[spp].splitlist[0] = (short *) space((number_of_points+1)*sizeof(short)); + SD[spp].splitlist[0][0] = elm; + SD[spp].splitlist[1] = (short *) space((number_of_points+1)*sizeof(short)); + SD[spp].splitlist[0][1] = elm; + for (i=1; i<= elm-1; i++) + SD[spp].splitlist[1][i] = i; + } + /* note that spp now points to the last entry in the splitlist !!! */ + + /* garbage collection .... unfortunately a bit boring */ + + for ( sp=1, new_sp=0; sp<= spp; sp++ ){ + if (full_slots[sp]){ + new_sp++; + if(sp != new_sp){ + /* copy all the junk from sp to new_sp */ + full_slots[new_sp]=1; full_slots[sp]=0; + SD[new_sp].splitsize = SD[sp].splitsize; + SD[new_sp].isolation_index = SD[sp].isolation_index; + if(SD[new_sp].splitlist[0]==NULL) + SD[new_sp].splitlist[0] = (short *) space((number_of_points+1)*sizeof(short)); + if(SD[new_sp].splitlist[1]==NULL) + SD[new_sp].splitlist[1] = (short *) space((number_of_points+1)*sizeof(short)); + for(i=0;i<=elm;i++){ + SD[new_sp].splitlist[0][i] = SD[sp].splitlist[0][i]; + SD[new_sp].splitlist[1][i] = SD[sp].splitlist[1][i]; + } + free(SD[sp].splitlist[0]); + SD[sp].splitlist[0] = NULL; + free(SD[sp].splitlist[1]); + SD[sp].splitlist[1] = NULL; + SD[sp].splitsize = 0; + SD[sp].isolation_index = 0.0; + } + } + } + n_of_splits = new_sp; + SD[0].splitsize = n_of_splits; +#if DEBUG + for(test1=0, i=2; i<=elm; i++) for( j=1; j %d Split Decomposition",x[0].splitsize); + for (k=1; k<=x[0].splitsize; k++) { + if( (x[k].splitlist[0])&&(x[k].splitlist[1]) ) { + printf("\n%3d %8.4f : {",k,x[k].isolation_index); + for(j=1;j<=x[k].splitsize;j++) + printf(" %3d",x[k].splitlist[0][j]); + printf(" |"); +#if SHORT_OUTPUT + printf(" ..."); +#else + for(j=1;j<=(x[k].splitlist[0][0]-x[k].splitsize);j++) + printf(" %3d",x[k].splitlist[1][j]); + printf(" } "); +#endif + } + } + printf("\n %8.4f : { [Split prime fraction] }\n", x[0].isolation_index); +} + + +/* -------------------------------------------------------------------------- */ + +int CompareSplit(const void *v1 , const void *v2) +{ + Split *S1, *S2; + + S1 = (Split *) v1; S2 = (Split *) v2; + if(S1->isolation_index < S2->isolation_index) return +1; + if(S2->isolation_index < S1->isolation_index) return -1; + return 0; +} + +/* -------------------------------------------------------------------------- */ + +PUBLIC void sort_Split(Split *x) +{ + int i,j; + int t1; + + qsort((void *) &(x[1]), x[0].splitsize ,sizeof(Split),CompareSplit ); + + for(i=1; i<=x[0].splitsize; i++) { + if(x[i].splitsize > x[i].splitlist[0][0]-x[i].splitsize) { + for(j=1; j<=x[i].splitsize; j++) { + t1 = x[i].splitlist[0][j]; + x[i].splitlist[0][j] = x[i].splitlist[1][j]; + x[i].splitlist[1][j] = t1; + } + x[i].splitsize = x[i].splitlist[0][0]-x[i].splitsize; + } + } +} + + +/* -------------------------------------------------------------------------- */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.h new file mode 100755 index 00000000..caa7079e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/split.h @@ -0,0 +1,14 @@ +typedef struct { + int *split_list[2]; + int split_size; + double isolation_index; } Split; + +extern Split *split_decomposition(float **dist); +extern void free_Split(Split *x); +extern void sort_Split(Split *x); +extern void print_Split(Split *x); + + +/* Auxiliary information contained in datatype 'Split': + Split[0].splitsize .... contains the total number of splits. +*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.c new file mode 100755 index 00000000..4bd03a5c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.c @@ -0,0 +1,513 @@ +/* Quadruple Statistics on an arbitrary alphabet + + Vienna RNA Package --- Peter F Stadler 1993 + +*/ + +#include +#include +#include +#include "utils.h" +#include "PS3D.h" +#include "distance_matrix.h" + +#define PUBLIC +#define PRIVATE static + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) +#define MIN4(A, B, C, D) MIN2( (MIN2((A),(B))), (MIN2((C),(D))) ) +#define MAX2(A, B) ((A) > (B) ? (A) : (B)) +#define MAX4(A, B, C, D) MAX2( (MAX2((A),(B))), (MAX2((C),(D))) ) + +PRIVATE int IBox[16]; + + +PUBLIC float *statgeom(char **seqs, int n_of_seqs); +PUBLIC float *statgeom4(char **ss[4], int nn[4]); +PUBLIC void printf_stg(float *B); + +PRIVATE void SingleBox(char *x1, char *x2, char *x3, char *x4); +PRIVATE void SortSingleBox(void); + +/* ----------------------------------------------------------------------- */ + +PUBLIC float *statgeom(char **seqs, int n_of_seqs) +{ + int i,j,k,l; + int i1; + + float *B; + float temp; + + if(n_of_seqs < 4) { + fprintf(stderr,"Less than 4 sequences for statistical geometry.\n"); + return NULL; + } + + B = (float *) space(16*sizeof(float)); + + for(i=3; i Statistical Geometry.\n"); + printf("> %d (sequence length)\n", (int) B[0]); + printf("> AAAA\n"); + printf(" %7.5f\n", B[1]); + printf("> BAAA ABAA AABA AAAB\n"); + printf(" %7.5f %7.5f %7.5f %7.5f\n", B[2],B[3],B[4],B[5]); + printf("> AABB ABAB ABBA\n"); + printf(" %7.5f %7.5f %7.5f\n", B[6],B[7],B[8]); + printf("> AABC ABAC ABCA BAAC BACA BCAA\n"); + printf(" %7.5f %7.5f %7.5f %7.5f %7.5f %7.5f\n" + ,B[9],B[10],B[11],B[12],B[13],B[14]); + printf("> ABCD\n"); + printf(" %7.5f\n",B[15]); +} + +/* ------------------------------------------------------------------------- */ + + +PUBLIC void SimplifiedBox(float *B, char *filename) +{ + char *tmp, temp[50]; + float X,Y,Z; + float T,P; + float t1, t2, t3, t4; + float p1, p2, p3, p4; + float x1, x2, y1, y2,z1,z2; + FILE *fp; + float view[3] = {0.3, 1.5, 0.1}; + float axis[3] = {1.0, 0.0, 0.0}; + + t1 = B[9]+B[10]+B[11]+B[15]; + t2 = B[9]+B[12]+B[13]+B[15]; + t3 = B[10]+B[12]+B[14]+B[15]; + t4 = B[11]+B[13]+B[14]+B[15]; + + p1 = B[2]; p2 = B[3]; p3 = B[4]; p4 = B[5]; + + x1 = B[6] + B[14]; + x2 = B[6] + B[9]; + y1 = B[7] + B[13]; + y2 = B[7] + B[10]; + z1 = B[8] + B[12]; + z2 = B[8] + B[11]; + + X = (x1+x2)/2.; Y = (y1+y2)/2.; Z = (z1+z2)/2; + T = (t1+t2+t3+t4)/4.; + P = (p1+p2+p3+p4)/4.; + + printf("> X = %7.5f \n",X); + printf("> Y = %7.5f \n",Y); + printf("> Z = %7.5f \n",Z); + printf("> T = %7.5f \n",T); + printf("> P = %7.5f \n",P); + + tmp = get_taxon_label(-1); /* retrieve the dataset identifier */ + + temp[0]='\0'; + if(tmp) { strcat(temp,tmp);strcat(temp,"_"); free(tmp); } + strcat(temp,filename); + + fp = fopen(temp,"w"); + if (fp!=NULL) { + ps3d_Preambel(fp, view, axis, "N"); + PS_DrawSimplifiedBox(X,Y,Z,T,P, fp); + fclose(fp); + } else fprintf(stderr,"couldn't open %s -- not drawing box\n", temp); +} + + + +/* ------------------------------------------------------------------------- */ + +PRIVATE void SingleBox(char *x1, char *x2, char *x3, char *x4) +{ + int len,i1,j1,k1,i,M,m; + int d[4]; + char t[4]; + + len=strlen(x1); + if(strlen(x2)!=len) nrerror("Sequences of unequal length in 'SingleBox'"); + if(strlen(x3)!=len) nrerror("Sequences of unequal length in 'SingleBox'"); + if(strlen(x4)!=len) nrerror("Sequences of unequal length in 'SingleBox'"); + + IBox[0] = len; + for(i=1; i<=15; i++) IBox[i] = 0; + + for(i1=0;i1= IBox[14] ) { /* 1,2 > 3,4 */ + IBB[9] = IBox[9]; + IBB[14] = IBox[14]; + if( IBox[7] >= IBox[8] ) { /* 13|24 */ + IBB[7] = IBox[7]; + IBB[8] = IBox[8]; + if( IBox[10] >= IBox[13] ) { /* 1>2>3>4 */ + IBB[10] = IBox[10]; + IBB[13] = IBox[13]; + IBB[11] = IBox[11]; + IBB[12] = IBox[12]; + s[0]=0; s[1]=1; s[2]=2; s[3]=3; /* 1 2 3 4 */ + } + else { /* 2>1>4>3 */ + IBB[10] = IBox[13]; + IBB[13] = IBox[10]; + IBB[11] = IBox[12]; + IBB[12] = IBox[11]; + s[0]=1; s[1]=0; s[2]=3; s[3]=2; /* 2 1 4 3 */ + } + } + else { /* 14|23 */ + IBB[7] = IBox[8]; + IBB[8] = IBox[7]; + if( IBox[11] >= IBox[12]) { /* 1>2>4>3 */ + IBB[10] = IBox[11]; + IBB[13] = IBox[12]; + IBB[11] = IBox[10]; + IBB[12] = IBox[13]; + s[0]=0; s[1]=1; s[2]=3; s[3]=2; /* 1 2 4 3 */ + } + else { /* 2>1>3>4 */ + IBB[10] = IBox[12]; + IBB[13] = IBox[11]; + IBB[11] = IBox[13]; + IBB[12] = IBox[10]; + s[0]=1; s[1]=0; s[2]=2; s[3]=3; /* 2 1 3 4 */ + } + } + } + else { /* 3,4 > 1,2 */ + IBB[9] = IBox[14]; + IBB[14]= IBox[9]; + if( IBox[7] >= IBox[8] ) { /* 31|42 */ + IBB[7] = IBox[7]; + IBB[8] = IBox[8]; + if(IBox[10] >= IBox[13]) { /* 3>4>1>2 */ + IBB[10] = IBox[10]; + IBB[13] = IBox[13]; + IBB[11] = IBox[12]; + IBB[12] = IBox[11]; + s[0]=2; s[1]=3; s[2]=0; s[3]=1; /* 3 4 1 2 */ + } + else { /* */ + IBB[10] = IBox[13]; + IBB[13] = IBox[10]; + IBB[11] = IBox[11]; + IBB[12] = IBox[12]; + s[0]=3; s[1]=2; s[2]=1; s[3]=0; /* 4 3 2 1 */ + } + } + else { /* 32|14 */ + IBB[7] = IBox[8]; + IBB[8] = IBox[7]; + if( IBox[11] >= IBox[12]) { /* 3>4>2>1 */ + IBB[10] = IBox[12]; + IBB[13] = IBox[11]; + IBB[11] = IBox[10]; + IBB[12] = IBox[13]; + s[0]=2; s[1]=3; s[2]=1; s[3]=0; /* 3 4 2 1 */ + } + else { /* 2>1>3>4 */ + IBB[10] = IBox[10]; + IBB[13] = IBox[13]; + IBB[11] = IBox[12]; + IBB[12] = IBox[11]; + s[0]=2; s[1]=3; s[2]=0; s[3]=1; /* 3 4 1 2 */ + } + } + } + } + else if (M == IBox[7] ) { /* 13|24 */ + IBB[6] = IBox[7]; + if( IBox[10] >= IBox[13] ) { /* 1,3 > 2,4 */ + IBB[9] = IBox[10]; + IBB[14] = IBox[13]; + if( IBox[6] >= IBox[8]) { /* 12|34 */ + IBB[7] = IBox[6]; + IBB[8] = IBox[8]; + if( IBox[9] >= IBox[14] ) { /* 1,2>3,4 */ + IBB[10] = IBox[9]; + IBB[13] = IBox[14]; + IBB[11] = IBox[11]; + IBB[12] = IBox[12]; + s[0]=0; s[1]=2; s[2]=1; s[3]=3; /* 1 3 2 4 */ + } + else { + IBB[10] = IBox[14]; + IBB[13] = IBox[9]; + IBB[11] = IBox[12]; + IBB[12] = IBox[11]; + s[0]=2; s[1]=0; s[2]=3; s[3]=1; /* 3 1 4 2 */ + } + } + else { /* 14|23 */ + IBB[7] = IBox[8]; + IBB[8] = IBox[6]; + if( IBox[11] >= IBox[12] ){ /* 1,4 > 2,3 */ + IBB[10] = IBox[11]; + IBB[13] = IBox[12]; + IBB[11] = IBox[9]; + IBB[12] = IBox[14]; + s[0]=0; s[1]=2; s[2]=3; s[3]=1; /* 1 3 4 2 */ + } + else { + IBB[10] = IBox[12]; + IBB[13] = IBox[11]; + IBB[11] = IBox[14]; + IBB[12] = IBox[9]; + s[0]=2; s[1]=0; s[2]=1; s[3]=3; /* 3 1 2 4 */ + } + } + } + else { /* 2,4 > 1,3 */ + IBB[9] = IBox[13]; + IBB[14] = IBox[10]; + if( IBox[6] >= IBox[8]) { /* 21|43 */ + IBB[7] = IBox[6]; + IBB[8] = IBox[8]; + if( IBox[9] >= IBox[14] ) { /* 2,1>4,3 */ + IBB[10] = IBox[9]; + IBB[13] = IBox[14]; + IBB[11] = IBox[12]; + IBB[12] = IBox[11]; + s[0]=1; s[1]=3; s[2]=0; s[3]=2; /* 2 4 1 3 */ + } + else { + IBB[10] = IBox[14]; + IBB[13] = IBox[9]; + IBB[11] = IBox[11]; + IBB[12] = IBox[12]; + s[0]=3; s[1]=1; s[2]=2; s[3]=0; /* 4 2 3 1 */ + } + } + else { /* 14|23 */ + IBB[7] = IBox[8]; + IBB[8] = IBox[6]; + if( IBox[11] >= IBox[12] ){ /* 1,4 > 2,3 */ + IBB[10] = IBox[11]; + IBB[13] = IBox[12]; + IBB[11] = IBox[14]; + IBB[12] = IBox[9]; + s[0]=3; s[1]=1; s[2]=0; s[3]=2; /* 4 2 1 3 */ + } + else { + IBB[10] = IBox[12]; + IBB[13] = IBox[11]; + IBB[11] = IBox[9]; + IBB[12] = IBox[14]; + s[0]=1; s[1]=3; s[2]=2; s[3]=0; /* 2 4 3 1 */ + } + } + } + } + else { /* 14 | 23 */ + IBB[6] = IBox[8]; + if( IBox[11] >= IBox[12] ) { /* 1,4 > 2,3 */ + IBB[9] = IBox[11]; + IBB[14] = IBox[12]; + if(IBox[6] >= IBox[7]) { /* 12|34 */ + IBB[7] = IBox[6]; + IBB[8] = IBox[7]; + if(IBox[9] >= IBox[14]) { /* 1,2>3,4 */ + IBB[10] = IBox[9]; + IBB[13] = IBox[14]; + IBB[11] = IBox[10]; + IBB[12] = IBox[13]; + s[0]=0; s[1]=3; s[2]=1; s[3]=2; /* 1 4 2 3 */ + } + else { /* 4,3>2,1 */ + IBB[10] = IBox[14]; + IBB[13] = IBox[9]; + IBB[11] = IBox[13]; + IBB[12] = IBox[10]; + s[0]=3; s[1]=0; s[2]=2; s[3]=1; /* 4 1 3 2 */ + } + } + else { /* 13|24 */ + IBB[7] = IBox[7]; + IBB[8] = IBox[6]; + if( IBox[10] >= IBox[13]) { /* 1,3 > 2,4 */ + IBB[10] = IBox[10]; + IBB[13] = IBox[13]; + IBB[11] = IBox[9]; + IBB[12] = IBox[14]; + s[0]=0; s[1]=3; s[2]=2; s[3]=1; /* 1 4 3 2 */ + } + else { + IBB[10] = IBox[13]; + IBB[13] = IBox[10]; + IBB[11] = IBox[14]; + IBB[12] = IBox[9]; + s[0]=3; s[1]=0; s[2]=1; s[3]=2; /* 4 1 2 3 */ + } + } + } + else { /* 2,3 > 1,4 */ + IBB[9] = IBox[12]; + IBB[14] = IBox[11]; + if(IBox[6] >= IBox[7]) { /* 34|12 */ + IBB[7] = IBox[6]; + IBB[8] = IBox[7]; + if(IBox[9] >= IBox[14]) { /* 2,1>4,3 */ + IBB[10] = IBox[9]; + IBB[13] = IBox[14]; + IBB[11] = IBox[13]; + IBB[12] = IBox[10]; + s[0]=1; s[1]=2; s[2]=0; s[3]=3; /* 2 3 1 4 */ + } + else { /* 4,3>2,1 */ + IBB[10] = IBox[14]; + IBB[13] = IBox[9]; + IBB[11] = IBox[10]; + IBB[12] = IBox[13]; + s[0]=2; s[1]=1; s[2]=3; s[3]=0; /* 3 2 4 1 */ + } + } + else { /* 31|42 */ + IBB[7] = IBox[7]; + IBB[8] = IBox[6]; + if( IBox[10] >= IBox[13]) { /* 1,3 > 2,4 */ + IBB[10] = IBox[10]; + IBB[13] = IBox[13]; + IBB[11] = IBox[14]; + IBB[12] = IBox[9]; + s[0]=2; s[1]=1; s[2]=0; s[3]=4; /* 3 2 1 4 */ + } + else { + IBB[10] = IBox[13]; + IBB[13] = IBox[10]; + IBB[11] = IBox[9]; + IBB[12] = IBox[14]; + s[0]=1; s[1]=2; s[2]=3; s[3]=0; /* 2 3 4 1 */ + } + } + } + } + /* HEUREKA */ + IBB[0] = IBox[0]; + IBB[1] = IBox[1]; + IBB[2] = IBox[2+s[0]]; + IBB[3] = IBox[2+s[1]]; + IBB[4] = IBox[2+s[2]]; + IBB[5] = IBox[2+s[3]]; + /* + IBB[6...14] see above :-) + */ + IBB[15] = IBox[15]; + + for(i=0;i<=15;i++) IBox[i] = IBB[i]; +} + +/* ----------------------------------------------------------------------- */ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.h new file mode 100755 index 00000000..75119173 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/statgeom.h @@ -0,0 +1,5 @@ +extern float *statgeom(char **seqs, int n_of_seqs); +extern float *statgeom4(char **ss[4], int nn[4]); +extern void printf_stg(float *B); +extern void SimplifiedBox(float *B, char *filename); + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.c new file mode 100755 index 00000000..7a53260d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.c @@ -0,0 +1,359 @@ +#include +#include +#include +#include "distance_matrix.h" +#include "utils.h" + +#define PUBLIC +#define PRIVATE static +#define MAX(A, B) ((A) > (B) ? (A) : (B)) +#define MIN(A, B) ((A) < (B) ? (A) : (B)) + +#define MAXTAXA_FOR_LABELS 200 + +typedef struct{ + int set1; + int set2; + float distance; + float distance2; + } Union; + +typedef struct _Node_ { + float height; + float brr; + float brl; + int whoami; + int size; + struct _Node_ *father; + struct _Node_ *left; + struct _Node_ *right; + } Node; + +PUBLIC void PSplot_phylogeny(Union *cluster, char *filename, char *type); + +PRIVATE Node *W2Phylo(Union *cluster); +PRIVATE Node *Nj2Phylo(Union *cluster); +PRIVATE void free_phylo_tree(Node *root); +PRIVATE void fill_height_into_tree(Node *root); +PRIVATE void fill_br_from_height(Node *root); +PRIVATE void plot_branch(Node *root, FILE *fp); +PRIVATE void format_number(float x); + +PRIVATE char str[10]; +PRIVATE float threshold; +PRIVATE int print_labels=1; + +/* --------------------------------------------------------------------------*/ + +PUBLIC void PSplot_phylogeny(Union *cluster, char *filename, char *type) +{ + int n; + char outfile[50]; + char *tmp, *tfont; + Node *root; + Node *tempnode; + FILE *fp; + float xsize, ysize, tfontsize, lfontsize, lwidth; + + n = cluster[0].set1; + switch(type[0]) { + case 'W' : + root = W2Phylo(cluster); + break; + case 'N' : + root = Nj2Phylo(cluster); + break; + default : + return; + } + + outfile[0] = '\0'; + tmp = get_taxon_label(-1); /* retrieve data set identifier */ + if(tmp) {strcat(outfile,tmp); strcat(outfile,"_"); free(tmp);} + strcat(outfile,filename); + + fp = fopen(outfile,"w"); + if (fp==NULL) { + fprintf(stderr,"couldn't open %s -- not doing treeplot\n", outfile); + return; + } + xsize = root->size; + tempnode = root; + while(tempnode->right) + tempnode = tempnode->right; + ysize = tempnode->height; + threshold = ysize*0.06; + + lwidth = MIN(1.5, 8/sqrt((double)n)); + tfontsize = MIN(15,550./(10+n)); + lfontsize = 2./3.*tfontsize; + if (n>30) tfont = "Helvetica"; + else tfont = "Times-Roman"; + if(n > MAXTAXA_FOR_LABELS) print_labels=0; + else print_labels=1; + fprintf(fp,"%%!PS-Adobe-2.0 EPSF-1.2\n"); + fprintf(fp,"%%%%Title: TreePlot (%s)\n",type); + fprintf(fp,"%%%%Creator: AnalyseDists\n"); + fprintf(fp,"%%%%CreationDate: %s", time_stamp()); + /* BoundingBox is only approximate */ + fprintf(fp,"%%%%BoundingBox: 35 45 535 640\n"); + fprintf(fp,"%%%%Pages: 1\n"); + fprintf(fp,"%%%%EndComments: No comment!\n"); + fprintf(fp,"288.5 50 translate\n"); + fprintf(fp,"%3.1f setlinewidth\n" + "/cmtx matrix currentmatrix def\n", lwidth); + fprintf(fp,"500 %g div 360 %g div scale\n", xsize, ysize); + fprintf(fp,"/rotshow {gsave cmtx setmatrix\n"); + fprintf(fp," 90 rotate 5 %4.1f rmoveto show grestore} def\n", + -tfontsize/4); + fprintf(fp,"/cshow {gsave cmtx setmatrix\n" + " /Helvetica findfont %4.1f scalefont setfont\n" + " 90 rotate 0 %3.1f rmoveto\n" + " dup stringwidth pop 2 div neg 0 rmoveto show\n" + " grestore} def\n", lfontsize, lfontsize/5); + fprintf(fp,"/%s findfont %4.1f scalefont setfont\n", tfont, tfontsize); + + fprintf(fp,"0 0 moveto\n"); + plot_branch(root,fp); + + fprintf(fp,"cmtx setmatrix stroke\nshowpage\n"); + free_phylo_tree(root); + fclose(fp); + +} + +/* --------------------------------------------------------------------------*/ + +PRIVATE Node *W2Phylo(Union *cluster) +{ + int i,n; + float b; + Node **taxa; + Node *father; + + n=cluster[0].set1; + taxa = (Node **) space(sizeof(Node*)*(n+1)); + + b = sqrt(MAX(cluster[n-1].distance,0.)); + for(i=1;i<=n;i++){ + taxa[i] = (Node *) space(sizeof(Node)); + taxa[i]->whoami = i; + taxa[i]->size = 1; + taxa[i]->height = b; + } + + for(i=1;iwhoami = 0; + father->left = taxa[cluster[i].set1]; + father->right = taxa[cluster[i].set2]; + father->size = father->left->size+father->right->size; + b = sqrt(MAX(cluster[n-1].distance-cluster[i].distance,0.)); + father->height = b; + father->left->father = father; + father->right->father = father; + taxa[cluster[i].set1] = father; + } + free(taxa); + father->whoami = -1; + fill_br_from_height(father); + return father; +} + + +/* --------------------------------------------------------------------------*/ + +PRIVATE void fill_br_from_height(Node *root) +{ + root->brr = root->right->height - root->height; + root->brl = root->left->height - root->height; + if(!root->left->whoami) fill_br_from_height(root->left); + if(!root->right->whoami) fill_br_from_height(root->right); + return; +} + +/* -------------------------------------------------------------------------- */ +#define ORDER(X) \ +if ((X)->brl>(X)->brr) { \ + xnode=(X)->right; \ + (X)->right=(X)->left; \ + (X)->left=xnode; \ + br = (X)->brr; \ + (X)->brr=(X)->brl; \ + (X)->brl=br; \ +} + + + +PRIVATE Node *Nj2Phylo(Union *cluster) +{ + int i,n, br; + float h1,h2,maxdist,dist; + Node **taxa; + Node *father; + Node *topnode; /* of the longest path in the tree */ + Node *tempnode, *xnode; + Node *root; + + maxdist = 0.; + n=cluster[0].set1; + taxa = (Node **) space(sizeof(Node*)*(n+1)); + + for(i=1;i<=n;i++){ + taxa[i] = (Node *) space(sizeof(Node)); + taxa[i]->whoami = i; + taxa[i]->size = 1; + } + + for(i=1;iwhoami = 0; + h1 = cluster[i].distance +taxa[cluster[i].set1]->height; + h2 = cluster[i].distance2+taxa[cluster[i].set2]->height; + dist = h1 + h2; + if(dist > maxdist) { + maxdist = dist; + topnode = father; + } + if(h1<=h2) { + father->brr = cluster[i].distance2; + father->brl = cluster[i].distance; + father->left = taxa[cluster[i].set1]; + father->right = taxa[cluster[i].set2]; + } + else { + father->brr = cluster[i].distance; + father->brl = cluster[i].distance2; + father->left = taxa[cluster[i].set2]; + father->right = taxa[cluster[i].set1]; + } + father->height = MAX(h1,h2); + father->size = father->left->size + father->right->size; + father->left->father = father; + father->right->father = father; + taxa[cluster[i].set1] = father; + } + + /* new root is inserted in the middle of the longest path */ + dist = maxdist/2.; + tempnode = topnode; + while (tempnode->height > dist) + tempnode = tempnode->right; + + topnode = tempnode->father; + /* new root must go between topnode and tempnode */ + h1 = dist - tempnode->height; + h2 = topnode->height - dist ; + + root = (Node *) space(sizeof(Node)); + root->father = NULL; + root->whoami = -1; + root->right = tempnode; + root->left = topnode; + root->height = 0.0; + root->brr = h1; + root->brl = h2; + root->size = n; + + topnode->size = n - tempnode->size; + + tempnode = root; + while(topnode->father) { + topnode->right = topnode->father; + topnode->brr = topnode->father->brr; + topnode->father = tempnode; + tempnode = topnode; + topnode = topnode->right; + topnode->size = tempnode->size - tempnode->left->size; + ORDER(tempnode); + } + /* topnode is now old root, remove it */ + if (tempnode->right==topnode) { + tempnode->right = topnode->left; + tempnode->brr = topnode->brr + topnode->brl; + tempnode->right->father = tempnode; + } else { + tempnode->left = topnode->left; + tempnode->brl = topnode->brr + topnode->brl; + tempnode->left->father = tempnode; + } + free(topnode); + ORDER(root); + + fill_height_into_tree(root); + + return root; +} + +/* -------------------------------------------------------------------------- */ + +PRIVATE void fill_height_into_tree(Node *root) +{ + if(root->whoami>0) return; + root->left->height = root->height + root->brl; + root->right->height = root->height + root->brr; + fill_height_into_tree(root->left); + fill_height_into_tree(root->right); + return; +} + +/* -------------------------------------------------------------------------- */ + +PRIVATE void free_phylo_tree(Node *root) { + if(root->left) free_phylo_tree(root->left); + if(root->right) free_phylo_tree(root->right); + free(root); +} + + +/* -------------------------------------------------------------------------- */ + +PRIVATE void plot_branch(Node *root, FILE *fp) +{ + char *label; + + fprintf(fp,"currentpoint %g 0 rlineto 0 %g rlineto \n", + -(float)(root->left->size)/2., root->brr); + if((print_labels)&&(root->brr > threshold)) { + format_number(root->brr); + fprintf(fp,"currentpoint 0 %g rlineto \n", -root->brr/2.); + fprintf(fp,"(%s) cshow moveto\n", str); + } + if(root->right->whoami==0) plot_branch(root->right,fp); + else if(print_labels) { + label = get_taxon_label(root->right->whoami); + fprintf(fp, "(%s) rotshow\n", label); + free(label); + } + fprintf(fp,"moveto\n"); + fprintf(fp,"currentpoint %g 0 rlineto 0 %g rlineto \n", + +(float)(root->right->size)/2., root->brl); + if((print_labels)&&(root->brl > threshold)) { + format_number(root->brl); + fprintf(fp,"currentpoint 0 %g rlineto \n", -root->brl/2.); + fprintf(fp,"(%s) cshow moveto\n",str); + } + if(root->left->whoami==0) plot_branch(root->left,fp); + else if(print_labels) { + label = get_taxon_label(root->left->whoami); + fprintf(fp, "(%s) rotshow\n", label); + free(label); + } + fprintf(fp,"moveto\n"); +} + +/* -------------------------------------------------------------------------- */ + +PRIVATE void format_number(float x) +{ + if(x >= 1.e5) { sprintf(str, "%4.1g",x ); return;} + if(x >= 100) { sprintf(str, "%.0f" ,x ); return;} + if(x >= 10) { sprintf(str, "%.1f", x ); return;} + if(x >= 1) { sprintf(str, "%.2f", x ); return;} + if(x >= 0.1) { sprintf(str, "%.2f", x ); return;} + if(x >= 0.01) { sprintf(str, "%.3f", x ); return;} + sprintf(str, "%4.1g",x ); + return; +} + +/* -------------------------------------------------------------------------- */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.h new file mode 100755 index 00000000..7897809a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/treeplot.h @@ -0,0 +1 @@ +extern void PSplot_phylogeny(Union *cluster, char *filename, char *type); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/utils.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/utils.h new file mode 100755 index 00000000..b0cbae0c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Cluster/utils.h @@ -0,0 +1,13 @@ +/* Header file for utils.c */ + +extern void *space(unsigned size); +extern void nrerror(char *message); +extern double urn(); +extern int int_urn(int from, int to); +extern void filecopy(FILE *from, FILE *to); +extern char *time_stamp(); +extern char *random_string(int l, char *symbols); +extern int hamming(char *s1, char *s2); +extern char *get_line(FILE *fp); +extern unsigned short xsubi[3]; + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/Makefile new file mode 100755 index 00000000..f7ad3d30 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/Makefile @@ -0,0 +1,378 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# H/Makefile. 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+/* write PostScript drawing of structure to file */ +extern int PS_rna_plot_a(char *string, char *structure, char *file, char *pre, char *post); +/* write PostScript drawing of structure to file with annotation */ +extern int gmlRNA(char *string, char *structure, char *ssfile, char option); +/* structure drawing in gml */ +extern int ssv_rna_plot(char *string, char *structure, char *ssfile); +/*write coord file for SStructView */ +extern int svg_rna_plot(char *string, char *structure, char *ssfile); +/*write RNAplot in SVG */ +extern int xrna_plot(char *string, char *structure, char *ssfile); +/*write .ss file for further editing in XRNA */ +extern int PS_dot_plot(char *string, char *file); +/* produce a PostScript dot plot of the pair probability matix */ +extern int rna_plot_type; /* 0= simple coordinates, 1= naview */ + +typedef struct cpair { + int i,j,mfe; + float p, hue, sat; +} cpair; +extern int PS_color_dot_plot(char *string, cpair *pi, char *filename); + +typedef struct plist { + int i; + int j; + float p; +}plist; +extern int PS_dot_plot_list(char *seq, char *filename, struct plist *pl, + struct plist *mf, char *comment); +extern int PS_dot_plot_turn(char *seq, struct plist *pl, char *filename, + int winSize); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/ProfileAln.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/ProfileAln.h new file mode 100755 index 00000000..4462e119 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/ProfileAln.h @@ -0,0 +1,10 @@ +#ifndef PROFILEALN_H +#define PROFILEALN_H + +extern float profile_aln(const float *T1, const char *seq1, + const float *T2, const char *seq2); + +extern int set_paln_params(double gap_open, double gap_ext, + double seqweight, int free_ends); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/RNAstruct.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/RNAstruct.h new file mode 100755 index 00000000..eb6cf246 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/RNAstruct.h @@ -0,0 +1,37 @@ +#define STRUC 1000 + +extern char *b2HIT(const char *structure); /* Full -> HIT [incl. root] */ +extern char *b2C(const char *structure); /* Full -> Coarse [incl. root] */ +extern char *b2Shapiro(const char *structure); /* Full -> weighted Shapiro [i.r.] */ +extern char *add_root(const char *); /* {Tree} -> ({Tree}R) */ + +extern char *expand_Shapiro(const char *coarse); +/* add S for stacks to coarse struct */ +extern char *expand_Full(const char *structure); /* Full -> FFull */ +extern char *unexpand_Full(const char *ffull); /* FFull -> Full */ +extern char *unweight(const char *wcoarse); /* remove weights from coarse struct */ + +extern void unexpand_aligned_F(char *align[2]); + +extern void parse_structure(const char *structure); /* make structure statistics */ + +extern int loop_size[STRUC]; /* loop sizes of a structure */ +extern int helix_size[STRUC]; /* helix sizes of a structure */ +extern int loop_degree[STRUC]; /* loop degrees of a structure */ +extern int loops; /* n of loops and stacks */ +extern int unpaired, pairs; /* n of unpaired digits and pairs */ + +/* + Example: + .((..(((...)))..((..)))). is the bracket or full tree + becomes expanded: - expand_Full() - + ((U)(((U)(U)((((U)(U)(U)P)P)P)(U)(U)(((U)(U)P)P)P)P)(U)R) + HIT: - b2HIT() - + ((U1)((U2)((U3)P3)(U2)((U2)P2)P2)(U1)R) + Coarse: - b2C() - + ((H)((H)M)R) + becomes expanded: - expand_Shapiro() - + (((((H)S)((H)S)M)S)R) + weighted Shapiro: - b2Shapiro() - + ((((((H3)S3)((H2)S2)M4)S2)E2)R) +*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/alifold.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/alifold.h new file mode 100755 index 00000000..bec45ed5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/alifold.h @@ -0,0 +1,14 @@ +extern float alifold(char **strings, char *structure); +extern void free_alifold_arrays(void); +extern void update_alifold_params(void); +extern double cv_fact /* =1 */; +extern double nc_fact /* =1 */; +typedef struct { + short i; /* i,j in [0, n-1] */ + short j; + float p; /* probability */ + float ent; /* pseudo entropy for p(i,j) = S_i + S_j - p_ij*ln(p_ij) */ + short bp[8]; /* frequencies of pair_types */ + char comp; /* 1 iff pair is in mfe structure */ +} pair_info; +extern float alipf_fold(char **sequences, char *structure, pair_info **pi); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/aln_util.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/aln_util.h new file mode 100755 index 00000000..1109b6f3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/aln_util.h @@ -0,0 +1,8 @@ +#ifndef ALN_UTIL_H +#define ALN_UTIL_H + +extern int read_clustal(FILE *clust, char *AlignedSeqs[], char *names[]); +extern /*@only@*/ /*@notnull@*/ char *consensus(const char *AS[]); +extern /*@only@*/ /*@notnull@*/ char *consens_mis(const char *AS[]); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/cofold.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/cofold.h new file mode 100755 index 00000000..90e559d4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/cofold.h @@ -0,0 +1,6 @@ +/* function from fold.c */ +extern float cofold(char *sequence, char *structure); +/* calculate energy of string on structure */ +extern void free_co_arrays(void); /* free arrays for mfe folding */ +extern void initialize_cofold(int length); /* allocate arrays for folding */ +extern void update_cofold_params(void); /* recalculate parameters */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/dist_vars.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/dist_vars.h new file mode 100755 index 00000000..92697205 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/dist_vars.h @@ -0,0 +1,31 @@ +#ifndef DIST_VARS_H +#define DIST_VARS_H +/* Global variables for Distance-Package */ + +extern int edit_backtrack; /* set to 1 if you want backtracking */ + +extern char *aligned_line[4]; /* containes alignment after backtracking */ + +extern int cost_matrix; /* 0 usual costs (default), 1 Shapiro's costs */ + +/* Global type defs for Distance-Package */ + +typedef struct { + int type; + int weight; + int father; + int sons; + int leftmostleaf; + } Postorder_list; + +typedef struct { + Postorder_list *postorder_list; + int *keyroots; + } Tree; + +typedef struct { + int type; + int sign; + float weight; + } swString; +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/duplex.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/duplex.h new file mode 100755 index 00000000..4d54c617 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/duplex.h @@ -0,0 +1,14 @@ +#ifndef DUPLEX_H +#define DUPLEX_H + +typedef struct { + int i; + int j; + char *structure; + float energy; +} duplexT; + +extern duplexT duplexfold(const char *s1, const char *s2); +extern duplexT *duplex_subopt(const char *s1, const char *s2, int delta, int w); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/edit_cost.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/edit_cost.h new file mode 100755 index 00000000..d1cc12d6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/edit_cost.h @@ -0,0 +1,54 @@ +/* + +cost.h :: global variables for Edit Costs + included by treedist.c and stringdist.c + +*/ +#define PRIVATE static + +PRIVATE char sep = ':'; +PRIVATE char *coding = "Null:U:P:H:B:I:M:S:E:R"; + +#define INF 10000 /* infinity */ + +typedef int CostMatrix[10][10]; + +PRIVATE CostMatrix *EditCost; /* will point to UsualCost or ShapiroCost */ + +PRIVATE CostMatrix UsualCost = +{ + +/* Null, U, P, H, B, I, M, S, E, R */ + + { 0, 1, 2, 2, 2, 2, 2, 1, 1, INF}, /* Null replaced */ + { 1, 0, 1, INF, INF, INF, INF, INF, INF, INF}, /* U replaced */ + { 2, 1, 0, INF, INF, INF, INF, INF, INF, INF}, /* P replaced */ + { 2, INF, INF, 0, 2, 2, 2, INF, INF, INF}, /* H replaced */ + { 2, INF, INF, 2, 0, 1, 2, INF, INF, INF}, /* B replaced */ + { 2, INF, INF, 2, 1, 0, 2, INF, INF, INF}, /* I replaced */ + { 2, INF, INF, 2, 2, 2, 0, INF, INF, INF}, /* M replaced */ + { 1, INF, INF, INF, INF, INF, INF, 0, INF, INF}, /* S replaced */ + { 1, INF, INF, INF, INF, INF, INF, INF, 0, INF}, /* E replaced */ + { INF, INF, INF, INF, INF, INF, INF, INF, INF, 0}, /* R replaced */ + +}; + + +PRIVATE CostMatrix ShapiroCost = +{ + +/* Null, U, P, H, B, I, M, S, E, R */ + + { 0, 1, 2, 100, 5, 5, 75, 5, 5, INF}, /* Null replaced */ + { 1, 0, 1, INF, INF, INF, INF, INF, INF, INF}, /* U replaced */ + { 2, 1, 0, INF, INF, INF, INF, INF, INF, INF}, /* P replaced */ + { 100, INF, INF, 0, 8, 8, 8, INF, INF, INF}, /* H replaced */ + { 5, INF, INF, 8, 0, 3, 8, INF, INF, INF}, /* B replaced */ + { 5, INF, INF, 8, 3, 0, 8, INF, INF, INF}, /* I replaced */ + { 75, INF, INF, 8, 8, 8, 0, INF, INF, INF}, /* M replaced */ + { 5, INF, INF, INF, INF, INF, INF, 0, INF, INF}, /* S replaced */ + { 5, INF, INF, INF, INF, INF, INF, INF, 0, INF}, /* E replaced */ + { INF, INF, INF, INF, INF, INF, INF, INF, INF, 0}, /* R replaced */ + +}; + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_const.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_const.h new file mode 100755 index 00000000..04892da4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_const.h @@ -0,0 +1,23 @@ +/* + + energy constants, formerly defined in + energy_par.h + + customized for use with RNAedit by + S.Kopp, IMB-Jena, Germany, Mar 1996 + +*/ + +#ifndef _ENERGY_CONST_H +#define _ENERGY_CONST_H 1 + +#define GASCONST 1.98717 /* in [cal/K] */ +#define K0 273.15 +#define INF 1000000 +#define FORBIDDEN 9999 +#define BONUS 10000 +#define NBPAIRS 7 +#define TURN 3 +#define MAXLOOP 30 + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_par.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_par.h new file mode 100755 index 00000000..fee8e3c6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/energy_par.h @@ -0,0 +1,60 @@ +/* + prototypes for energy_par.c +*/ + +#include "energy_const.h" + +extern double lxc37; /* parameter for logarithmic loop + energy extrapolation */ + +extern int stack37[NBPAIRS+1][NBPAIRS+1]; +extern int enthalpies[NBPAIRS+1][NBPAIRS+1]; /* stack enthalpies */ +extern int entropies[NBPAIRS+1][NBPAIRS+1]; /* not used anymore */ + +extern int hairpin37[31]; +extern int bulge37[31]; +extern int internal_loop37[31]; +extern int internal2_energy; +extern int old_mismatch_37[NBPAIRS+1][5][5]; +extern int mismatchI37[NBPAIRS+1][5][5]; /* interior loop mismatches */ +extern int mismatchH37[NBPAIRS+1][5][5]; /* same for hairpins */ +extern int mismatchM37[NBPAIRS+1][5][5]; /* same for multiloops */ +extern int mism_H[NBPAIRS+1][5][5]; /* mismatch enthalpies */ + +extern int dangle5_37[NBPAIRS+1][5]; /* 5' dangle exterior of pair */ +extern int dangle3_37[NBPAIRS+1][5]; /* 3' dangle */ +extern int dangle3_H[NBPAIRS+1][5]; /* corresponding enthalpies */ +extern int dangle5_H[NBPAIRS+1][5]; + +extern int int11_37[NBPAIRS+1][NBPAIRS+1][5][5]; /* 1x1 interior loops */ +extern int int11_H[NBPAIRS+1][NBPAIRS+1][5][5]; + +extern int int21_37[NBPAIRS+1][NBPAIRS+1][5][5][5]; /* 2x1 interior loops */ +extern int int21_H[NBPAIRS+1][NBPAIRS+1][5][5][5]; + +extern int int22_37[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; /* 2x2 interior loops */ +extern int int22_H[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; + +/* constants for linearly destabilizing contributions for multi-loops + F = ML_closing + ML_intern*(k-1) + ML_BASE*u */ +extern int ML_BASE37; +extern int ML_closing37; +extern int ML_intern37; + +/* Ninio-correction for asymmetric internal loops with branches n1 and n2 */ +/* ninio_energy = min{max_ninio, |n1-n2|*F_ninio[min{4.0, n1, n2}] } */ +extern int MAX_NINIO; /* maximum correction */ +extern int F_ninio37[5]; + +/* penalty for helices terminated by AU (actually not GC) */ +extern int TerminalAU; +/* penalty for forming bi-molecular duplex */ +extern int DuplexInit; +/* stabilizing contribution due to special hairpins of size 4 (tetraloops) */ +extern char Tetraloops[]; /* string containing the special tetraloops */ +extern int TETRA_ENERGY37[]; /* Bonus energy for special tetraloops */ +extern int TETRA_ENTH37; +extern char Triloops[]; /* string containing the special triloops */ +extern int Triloop_E37[]; /* Bonus energy for special Triloops */ + +extern double Tmeasure; /* temperature of param measurements */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold.h new file mode 100755 index 00000000..703aa2d0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold.h @@ -0,0 +1,8 @@ +/* function from fold.c */ +extern float fold(const char *sequence, char *structure); +/* calculate mfe-structure of sequence */ +extern float energy_of_struct(const char *string, const char *structure); +/* calculate energy of string on structure */ +extern void free_arrays(void); /* free arrays for mfe folding */ +extern void initialize_fold(int length); /* allocate arrays for folding */ +extern void update_fold_params(void); /* recalculate parameters */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold_vars.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold_vars.h new file mode 100755 index 00000000..815e790c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/fold_vars.h @@ -0,0 +1,36 @@ +/* to use floats instead of doubles in pf_fold() comment next line */ +#define LARGE_PF +#ifdef LARGE_PF +#define FLT_OR_DBL double +#else +#define FLT_OR_DBL float +#endif + +extern int noGU; /* GU not allowed at all */ +extern int no_closingGU; /* GU allowed only inside stacks */ +extern int tetra_loop; /* Fold with specially stable 4-loops */ +extern int energy_set; /* 0 = BP; 1=any mit GC; 2=any mit AU-parameter */ +extern int dangles; /* use dangling end energies (not in part_func!) */ +/*@null@*/ +extern char *nonstandards; /* contains allowed non standard bases */ +extern double temperature; /* rescale parameters to this temperature */ +extern int james_rule; /* interior loops of size 2 get energy 0.8Kcal and + no mismatches, default 1 */ +extern int logML; /* use logarithmic multiloop energy function */ +extern int cut_point; /* first position of 2nd strand for co-folding */ + +typedef struct bond { /* base pair */ + int i; + int j; +} bondT; +extern bondT *base_pair; /* list of base pairs */ + +extern FLT_OR_DBL *pr; /* base pairing prob. matrix */ +extern int *iindx; /* pr[i,j] -> pr[iindx[i]-j] */ +extern double pf_scale; /* scaling factor to avoid float overflows*/ +extern int fold_constrained; /* fold with constraints */ +extern int do_backtrack; /* calculate pair prob matrix in part_func() */ +extern int noLonelyPairs; /* avoid helices of length 1 */ +extern char backtrack_type; /* usually 'F'; 'C' require (1,N) to be bonded; + 'M' seq is part of a multi loop */ +char * option_string(void); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/inverse.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/inverse.h new file mode 100755 index 00000000..e443dc7b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/inverse.h @@ -0,0 +1,18 @@ +/* prototypes from inverse.c */ +extern char *symbolset; /* alphabet default is "AUGC" */ +extern float inverse_fold(char *start, const char *target); +/* find sequences with predefined structure. + the found sequence is written to start, + return value is + energy_of_struct(start, target) - fold(start, structure), + i.e. 0. if search was successful; */ + +extern float inverse_pf_fold(char *start, const char *target); +/* inverse folding maximising the frequency of target in the + ensemble of structures, final sequence is written to start, returns + energy_of_struct(start, target) - part_func(start, structure) +*/ +extern float final_cost; /* when to stop inverse_pf_fold() */ +extern int give_up; /* default 0: try to minimize structure distance even if + no exact solution can be found */ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/pair_mat.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/pair_mat.h new file mode 100755 index 00000000..0e4b2a09 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/pair_mat.h @@ -0,0 +1,117 @@ +#include +#define NBASES 8 +/*@notnull@*/ +static const char Law_and_Order[] = "_ACGUTXKI"; +static int BP_pair[NBASES][NBASES]= +/* _ A C G U X K I */ +{{ 0, 0, 0, 0, 0, 0, 0, 0}, + { 0, 0, 0, 0, 5, 0, 0, 5}, + { 0, 0, 0, 1, 0, 0, 0, 0}, + { 0, 0, 2, 0, 3, 0, 0, 0}, + { 0, 6, 0, 4, 0, 0, 0, 6}, + { 0, 0, 0, 0, 0, 0, 2, 0}, + { 0, 0, 0, 0, 0, 1, 0, 0}, + { 0, 6, 0, 0, 5, 0, 0, 0}}; + +#define MAXALPHA 20 /* maximal length of alphabet */ + +static short alias[MAXALPHA+1]; +static int pair[MAXALPHA+1][MAXALPHA+1]; +/* rtype[pair[i][j]]:=pair[j][i] */ +static int rtype[8] = {0, 2, 1, 4, 3, 6, 5, 7}; + +/* for backward compatibility */ +#define ENCODE(C) encode_char(c) + +static int encode_char(char c) { + /* return numerical representation of base used e.g. in pair[][] */ + int code; + if (energy_set>0) code = (int) (c-'A')+1; + else { + char *pos; + pos = strchr(Law_and_Order, c); + if (pos==NULL) code=0; + else code = (int) (pos-Law_and_Order); + if (code>4) code--; /* make T and U equivalent */ + } + return code; +} + +/*@+boolint +charint@*/ +/*@null@*/ +extern char *nonstandards; +extern void nrerror(const char message[]); +static void make_pair_matrix(void) +{ + int i,j; + + if (energy_set==0) { + for (i=0; i<5; i++) alias[i] = (short) i; + alias[5] = 3; /* X <-> G */ + alias[6] = 2; /* K <-> C */ + alias[7] = 0; /* I <-> default base '@' */ + for (i=0; i G */ + alias[i++] = 2; /* B <-> C */ + } + for (i=1; i GC */ + i++; + pair[i][i-1] = 1; /* BA <-> CG */ + } + } + else if (energy_set==2) { + for (i=1; i A*/ + alias[i++] = 4; /* B <-> U */ + } + for (i=1; i AU */ + i++; + pair[i][i-1] = 6; /* BA <-> UA */ + } + } + else if (energy_set==3) { + for (i=1; i G */ + alias[i++] = 2; /* B <-> C */ + alias[i++] = 1; /* C <-> A */ + alias[i++] = 4; /* D <-> U */ + } + for (i=1; i GC */ + i++; + pair[i][i-1] = 1; /* BA <-> CG */ + i++; + pair[i][i+1] = 5; /* CD <-> AU */ + i++; + pair[i][i-1] = 6; /* DC <-> UA */ + } + } + else nrerror("What energy_set are YOU using??"); + for (i=0; i<=MAXALPHA; i++) { + for (j=0; j<=MAXALPHA; j++) + rtype[pair[i][j]] = pair[j][i]; + } + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/params.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/params.h new file mode 100755 index 00000000..46d6122f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/params.h @@ -0,0 +1,32 @@ +#include "energy_const.h" +typedef struct { + int id; + int stack[NBPAIRS+1][NBPAIRS+1]; + int hairpin[31]; + int bulge[MAXLOOP+1]; + int internal_loop[MAXLOOP+1]; + int mismatchI[NBPAIRS+1][5][5]; + int mismatchH[NBPAIRS+1][5][5]; + int mismatchM[NBPAIRS+1][5][5]; + int dangle5[NBPAIRS+1][5]; + int dangle3[NBPAIRS+1][5]; + int int11[NBPAIRS+1][NBPAIRS+1][5][5]; + int int21[NBPAIRS+1][NBPAIRS+1][5][5][5]; + int int22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; + int F_ninio[5]; + double lxc; + int MLbase; + int MLintern[NBPAIRS+1]; + int MLclosing; + int TerminalAU; + int DuplexInit; + int TETRA_ENERGY[200]; + char Tetraloops[1401]; + int Triloop_E[40]; + char Triloops[241]; + double temperature; +} paramT; + +extern paramT *scale_parameters(void); +extern paramT *copy_parameters(void); +extern paramT *set_parameters(paramT *dest); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func.h new file mode 100755 index 00000000..633f1898 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func.h @@ -0,0 +1,8 @@ +/* functions from part_func.c */ +extern float pf_fold(char *sequence, char *structure); +/* calculate partition function and base pair probabilities */ +extern void init_pf_fold(int length); /* allocate space for pf_fold() */ +extern void free_pf_arrays(void); /* free arrays from pf_fold() */ +extern void update_pf_params(int length); /*recalculate energy parameters */ +extern char bppm_symbol(const float *x); /* string representation of structure */ +extern double mean_bp_dist(int length); /* mean pair distance of ensemble */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func_co.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func_co.h new file mode 100755 index 00000000..484d34d9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/part_func_co.h @@ -0,0 +1,56 @@ +/* functions from part_func.c */ +/* calculate partition function and base pair probabilities */ +#define LARGE_PF +#ifdef LARGE_PF +#define FLT_OR_DBL double +#else +#define FLT_OR_DBL float +#endif +extern int mirnatog; /*toggles no intrabp in 2nd mol*/ + +typedef struct cofoldF { + /* free energies for: */ + double F0AB; /* null model without DuplexInit */ + double FAB; /* all states with DuplexInit corretion */ + double FcAB; /* true hybrid states only */ + double FA; /* monomer A */ + double FB; /* monomer B */ +} cofoldF; + +extern cofoldF co_pf_fold(char *sequence, char *structure); /* calculate partition function and base pair probabilities */ +extern void init_co_pf_fold(int length); +extern void free_co_pf_arrays(void); +extern void update_co_pf_params(int length); /*recalculate energy parameters */ +extern char co_bppm_symbol(float *x); /* string representation of structure */ +extern void compute_probabilities(double FAB, double FEA, double FEB, + struct plist *prAB, + struct plist *prA, struct plist *prB, + int Alength); + + +typedef struct ConcEnt { + double A0; /*start concentration A*/ + double B0; /*start concentration B*/ + double ABc; /*End concentration AB*/ + double AAc; + double BBc; + double Ac; + double Bc; +} ConcEnt; + + + +typedef struct pairpro{ + struct plist *AB; + struct plist *AA; + struct plist *A; + struct plist *B; + struct plist *BB; +}pairpro; + + +extern struct ConcEnt *get_concentrations(double FEAB, double FEAA, double FEBB, double FEA, double FEB, double * startconc); + +extern struct plist *get_plist(struct plist *pl, int length, double cut_off); + +extern int make_probsum(int length, char *name); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/profiledist.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/profiledist.h new file mode 100755 index 00000000..c1507de7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/profiledist.h @@ -0,0 +1,14 @@ + +extern float *Make_bp_profile(int length); +/* condense pair probability matrix pr into a vector containing probabilities + for upstream paired, downstream paired and unpaired. This resulting + probability profile is used as input for profile_edit_distance */ + +extern float profile_edit_distance(const float *T1, const float *T2); +/* align two probability profiles */ + +extern void print_bppm(const float *T); +/* print string representation of probability profile */ + +extern void free_profile(float *T); +/* free space allocated in Make_bp_profile */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/stringdist.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/stringdist.h new file mode 100755 index 00000000..ba3383d4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/stringdist.h @@ -0,0 +1,7 @@ +#ifndef DIST_VARS_H +#include "dist_vars.h" /* defines the type Tree */ +#endif +extern swString *Make_swString(char *string); +/* make input for string_edit_distance */ +extern float string_edit_distance(swString *T1, swString *T2); +/* compare to structures using string alignment */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/subopt.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/subopt.h new file mode 100755 index 00000000..b20643ab --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/subopt.h @@ -0,0 +1,12 @@ +/* subopt.h */ +typedef struct { + float energy; /* energy of structure */ + char *structure; +} SOLUTION; + +extern SOLUTION *subopt (char *seq, char *sequence, int delta, FILE *fp); + /* returns list of subopt structures or writes to fp */ + +extern int subopt_sorted; /* sort output by energy */ + +/* End of file */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/treedist.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/treedist.h new file mode 100755 index 00000000..fd928c39 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/treedist.h @@ -0,0 +1,8 @@ +#ifndef DIST_VARS_H +#include "dist_vars.h" /* defines the type Tree */ +#endif +extern Tree *make_tree(char *struc); /* make input for tree_edit_distance */ +extern float tree_edit_distance(Tree *T1, Tree *T2); +/* compare to structures using tree editing */ +extern void print_tree(Tree *t); /* mainly for debugging */ +extern void free_tree(Tree *t); /* free space allocated by make_tree */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/utils.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/utils.h new file mode 100755 index 00000000..2fda4f11 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/H/utils.h @@ -0,0 +1,41 @@ +/* Header file for utils.c */ +#ifdef HAVE_CONFIG_H +#include +#endif +#ifdef WITH_DMALLOC +/* use dmalloc library to check for memory management bugs */ +#include "dmalloc.h" +#define space(S) calloc(1,(S)) +#else +extern /*@only@*/ /*@notnull@*/ +void *space(unsigned size) /*@ensures MaxSet(result) == (size-1);@*/; + /* allocate space safely */ +extern /*@only@*/ /*@notnull@*/ +void *xrealloc(/*@null@*/ /*@only@*/ /*@out@*/ /*@returned@*/ void *p, unsigned size) /*@modifies *p @*/ /*@ensures MaxSet(result) == (size-1) @*/; +#endif + +extern /*@exits@*/ void nrerror(const char message[]); /* die with error message */ +extern void init_rand(void); /* make random number seeds */ +extern unsigned short xsubi[3]; /* current 48bit random number */ +extern double urn(void); /* random number from [0..1] */ +extern int int_urn(int from, int to); /* random integer */ +extern void filecopy(FILE *from, FILE *to); /* inefficient `cp' */ +extern /*@observer@*/ char *time_stamp(void); /* current date in a string */ +extern /*@only@*/ /*@notnull@*/ char *random_string(int l, const char symbols[]); +/* random string of length l using characters from symbols[] */ +extern int hamming(const char *s1, const char *s2); +/* calculate hamming distance */ +extern /*@only@*/ /*@null@*/ char *get_line(const FILE *fp); /* read one (arbitrary length) line from fp */ + + +extern char *pack_structure(const char *struc); +/* pack secondary secondary structure, 5:1 compression using base 3 encoding */ +extern char *unpack_structure(const char *packed); +/* unpack sec structure packed with pack_structure() */ +extern short *make_pair_table(const char *structure); +/* returns a newly allocated table, such that: table[i]=j if (i.j) pair or + 0 if i is unpaired, table[0] contains the length of the structure. */ + +extern int bp_distance(const char *str1, const char *str2); +/* dist = {number of base pairs in one structure but not in the other} + same as edit distance with open-pair close-pair as move-set */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL new file mode 100755 index 00000000..40e57398 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL @@ -0,0 +1,91 @@ +Installation: + +This package uses GNU autoconf generated configure scripts, see the +file INSTALL.configure for generic configure documentation. + +Quickstart: Usually you'll just have to type: +---------- + ./configure + make +and (as root) + make install + +Install Paths: +------------- +The main programs, library, man, and info pages are +installed in the usual places by default +(i.e. /usr/local/{bin,lib,man,info}). In addition the following +install paths are used: +header files /usr/local/include/ViennaRNA [includedir/ViennaRNA] +parameter files /usr/local/share/ViennaRNA [datadir/ViennaRNA] +extra scripts /usr/local/share/ViennaRNA/bin [datadir/ViennaRNA/bin] +documentation /usr/local/share/ViennaRNA/doc [datadir/ViennaRNA/doc] + +All these locations can be changed by calling ./configure with +appropriate options. + +If you like having all software packages separated in their own directories +you could run e.g.: +./configure --prefix=/opt/packages/ViennaRNA --datadir=/opt/packages/ViennaRNA +resulting in /opt/packages/ViennaRNA/{bin,lib,man,info,include,doc} directories + +The installed location of the Perl module is determined by Perl's own +configuration, independent of any configure options. +To leave out the Perl modules run + ./configure --without-perl + +The programs AnalyseSeqs and AnalyseDists offer some cluster analysis +tools (split decomposition, statistical geometry, neighbor joining, +Ward's method) for sequences and distance data. To also build these +programs add --with-cluster to your configure options. + +This release includes the RNAforester and Kinfold programs, which can also +be obtained as independent packages. Running ./configure in the ViennaRNA +directory will configure those two packages as well. However, for detailed +information and compile time options, see the README and INSTALL files in +the respective subdirectories. + +The Kinfold program can be used to simulate the folding dynamics of an +RNA molecule, and is compiled by default. Use the --without-kinfold +option to skip compiling Kinfold. + +The RNAforester program is used for comparing secondary structures using +tree alignment. To compile RNAforester you'll need to first install the +g2 graphic library, then run configure with the --with-forester option. + +Calculation of partition functions (via RNAfold -p) uses double +precision floats by default, to avoid overflow errors on longer sequences. +If your machine has little memory and you dont't plan to fold sequences +over 1000 bases in length you can compile the package to do the computions +in single precision by giving ./configure the --enable-floatpf option. + +Memory requirements for a sequence of length n will be approximately +12*n^2 bytes for RNAfold -p in the double precision version, and + 4*n^2 bytes for the minimum free energy alone. + + +The readseq program is not integrated in the build process. If desired, +install readseq manually, following the instructions in the readseq +directory. + +There are man pages for all executables, the library is documented in +./man/RNAlib.texinfo. You can either print this file as a manual using +TeX (if you don't have texinfo.tex installed use the .dvi file) or use +it as online documentation if you have the GNU texinfo package installed. +Documentation in HTML can be found at http://www.tbi.univie.ac.at/~ivo/RNA/ + + +System specific notes: +calculating the partition function for long sequences ( >400 bases) +generates a lot of floating point underflows. On some system this can slow +down the calculation dramatically because an exception is invoked for each +underflow. How to avoid this problem is highly system specific: + +On SunOS 4.1 the remedy is calling nonstandard_arithmetic() add a -DSUN4 to +the CFLAGS in lib/makefile to do this. Use CC=gcc since SUN's standard cc +doesn't understand ANSI C. + +On HP machines running hpux-9 or hpux-10 add -DHP9 to the CFLAGS so that +fpsetfastmode() will be called. + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL.configure b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL.configure new file mode 100755 index 00000000..b42a17ac --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/INSTALL.configure @@ -0,0 +1,182 @@ +Basic Installation +================== + + These are generic installation instructions. + + The `configure' shell script attempts to guess correct values for +various system-dependent variables used during compilation. It uses +those values to create a `Makefile' in each directory of the package. +It may also create one or more `.h' files containing system-dependent +definitions. Finally, it creates a shell script `config.status' that +you can run in the future to recreate the current configuration, a file +`config.cache' that saves the results of its tests to speed up +reconfiguring, and a file `config.log' containing compiler output +(useful mainly for debugging `configure'). + + If you need to do unusual things to compile the package, please try +to figure out how `configure' could check whether to do them, and mail +diffs or instructions to the address given in the `README' so they can +be considered for the next release. If at some point `config.cache' +contains results you don't want to keep, you may remove or edit it. + + The file `configure.in' is used to create `configure' by a program +called `autoconf'. You only need `configure.in' if you want to change +it or regenerate `configure' using a newer version of `autoconf'. + +The simplest way to compile this package is: + + 1. `cd' to the directory containing the package's source code and type + `./configure' to configure the package for your system. If you're + using `csh' on an old version of System V, you might need to type + `sh ./configure' instead to prevent `csh' from trying to execute + `configure' itself. + + Running `configure' takes awhile. While running, it prints some + messages telling which features it is checking for. + + 2. Type `make' to compile the package. + + 3. Optionally, type `make check' to run any self-tests that come with + the package. + + 4. Type `make install' to install the programs and any data files and + documentation. + + 5. You can remove the program binaries and object files from the + source code directory by typing `make clean'. To also remove the + files that `configure' created (so you can compile the package for + a different kind of computer), type `make distclean'. There is + also a `make maintainer-clean' target, but that is intended mainly + for the package's developers. If you use it, you may have to get + all sorts of other programs in order to regenerate files that came + with the distribution. + +Compilers and Options +===================== + + Some systems require unusual options for compilation or linking that +the `configure' script does not know about. You can give `configure' +initial values for variables by setting them in the environment. Using +a Bourne-compatible shell, you can do that on the command line like +this: + CC=c89 CFLAGS=-O2 LIBS=-lposix ./configure + +Or on systems that have the `env' program, you can do it like this: + env CPPFLAGS=-I/usr/local/include LDFLAGS=-s ./configure + +Compiling For Multiple Architectures +==================================== + + You can compile the package for more than one kind of computer at the +same time, by placing the object files for each architecture in their +own directory. To do this, you must use a version of `make' that +supports the `VPATH' variable, such as GNU `make'. `cd' to the +directory where you want the object files and executables to go and run +the `configure' script. `configure' automatically checks for the +source code in the directory that `configure' is in and in `..'. + + If you have to use a `make' that does not supports the `VPATH' +variable, you have to compile the package for one architecture at a time +in the source code directory. After you have installed the package for +one architecture, use `make distclean' before reconfiguring for another +architecture. + +Installation Names +================== + + By default, `make install' will install the package's files in +`/usr/local/bin', `/usr/local/man', etc. You can specify an +installation prefix other than `/usr/local' by giving `configure' the +option `--prefix=PATH'. + + You can specify separate installation prefixes for +architecture-specific files and architecture-independent files. If you +give `configure' the option `--exec-prefix=PATH', the package will use +PATH as the prefix for installing programs and libraries. +Documentation and other data files will still use the regular prefix. + + In addition, if you use an unusual directory layout you can give +options like `--bindir=PATH' to specify different values for particular +kinds of files. Run `configure --help' for a list of the directories +you can set and what kinds of files go in them. + + If the package supports it, you can cause programs to be installed +with an extra prefix or suffix on their names by giving `configure' the +option `--program-prefix=PREFIX' or `--program-suffix=SUFFIX'. + +Optional Features +================= + + Some packages pay attention to `--enable-FEATURE' options to +`configure', where FEATURE indicates an optional part of the package. +They may also pay attention to `--with-PACKAGE' options, where PACKAGE +is something like `gnu-as' or `x' (for the X Window System). The +`README' should mention any `--enable-' and `--with-' options that the +package recognizes. + + For packages that use the X Window System, `configure' can usually +find the X include and library files automatically, but if it doesn't, +you can use the `configure' options `--x-includes=DIR' and +`--x-libraries=DIR' to specify their locations. + +Specifying the System Type +========================== + + There may be some features `configure' can not figure out +automatically, but needs to determine by the type of host the package +will run on. Usually `configure' can figure that out, but if it prints +a message saying it can not guess the host type, give it the +`--host=TYPE' option. TYPE can either be a short name for the system +type, such as `sun4', or a canonical name with three fields: + CPU-COMPANY-SYSTEM + +See the file `config.sub' for the possible values of each field. If +`config.sub' isn't included in this package, then this package doesn't +need to know the host type. + + If you are building compiler tools for cross-compiling, you can also +use the `--target=TYPE' option to select the type of system they will +produce code for and the `--build=TYPE' option to select the type of +system on which you are compiling the package. + +Sharing Defaults +================ + + If you want to set default values for `configure' scripts to share, +you can create a site shell script called `config.site' that gives +default values for variables like `CC', `cache_file', and `prefix'. +`configure' looks for `PREFIX/share/config.site' if it exists, then +`PREFIX/etc/config.site' if it exists. Or, you can set the +`CONFIG_SITE' environment variable to the location of the site script. +A warning: not all `configure' scripts look for a site script. + +Operation Controls +================== + + `configure' recognizes the following options to control how it +operates. + +`--cache-file=FILE' + Use and save the results of the tests in FILE instead of + `./config.cache'. Set FILE to `/dev/null' to disable caching, for + debugging `configure'. + +`--help' + Print a summary of the options to `configure', and exit. + +`--quiet' +`--silent' +`-q' + Do not print messages saying which checks are being made. To + suppress all normal output, redirect it to `/dev/null' (any error + messages will still be shown). + +`--srcdir=DIR' + Look for the package's source code in directory DIR. Usually + `configure' can determine that directory automatically. + +`--version' + Print the version of Autoconf used to generate the `configure' + script, and exit. + +`configure' also accepts some other, not widely useful, options. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/baum.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/baum.Po new file mode 100755 index 00000000..a96f3cb7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/baum.Po @@ -0,0 +1,103 @@ +baum.o baum.o: baum.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/assert.h ../H/fold_vars.h \ + ../H/fold.h ../H/utils.h ./config.h ../H/pair_mat.h \ + /usr/include/ctype.h nachbar.h globals.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/assert.h: + +../H/fold_vars.h: + +../H/fold.h: + +../H/utils.h: + +./config.h: + +../H/pair_mat.h: + +/usr/include/ctype.h: + +nachbar.h: + +globals.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/cache.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/cache.Po new file mode 100755 index 00000000..fb3bc924 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/cache.Po @@ -0,0 +1,102 @@ +cache.o cache.o: cache.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h ../H/utils.h \ + ./config.h cache_util.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/utils.h: + +./config.h: + +cache_util.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt.Po new file mode 100755 index 00000000..f4e11a5e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt.Po @@ -0,0 +1,49 @@ +getopt.o getopt.o: getopt.c ./config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/gnu-versions.h + +./config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/gnu-versions.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt1.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt1.Po new file mode 100755 index 00000000..114d616f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/getopt1.Po @@ -0,0 +1,51 @@ +getopt1.o getopt1.o: getopt1.c ./config.h getopt.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/gnu-versions.h + +./config.h: + +getopt.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/gnu-versions.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/globals.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/globals.Po new file mode 100755 index 00000000..9eab258c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/globals.Po @@ -0,0 +1,104 @@ +globals.o globals.o: globals.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/assert.h /usr/include/errno.h \ + /usr/include/bits/errno.h /usr/include/linux/errno.h \ + /usr/include/asm/errno.h ./getopt.h ../H/utils.h ./config.h globals.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/assert.h: + +/usr/include/errno.h: + +/usr/include/bits/errno.h: + +/usr/include/linux/errno.h: + +/usr/include/asm/errno.h: + +./getopt.h: + +../H/utils.h: + +./config.h: + +globals.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/main.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/main.Po new file mode 100755 index 00000000..d70751c2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/main.Po @@ -0,0 +1,114 @@ +main.o main.o: main.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/assert.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h ./getopt.h ../H/fold_vars.h ../H/fold.h \ + baum.h nachbar.h cache_util.h ../H/utils.h ./config.h globals.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/assert.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +./getopt.h: + +../H/fold_vars.h: + +../H/fold.h: + +baum.h: + +nachbar.h: + +cache_util.h: + +../H/utils.h: + +./config.h: + +globals.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/nachbar.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/nachbar.Po new file mode 100755 index 00000000..0efa1acd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/.deps/nachbar.Po @@ -0,0 +1,133 @@ +nachbar.o nachbar.o: nachbar.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h globals.h \ + /usr/include/assert.h ../H/fold_vars.h ../H/energy_const.h ../H/utils.h \ + ./config.h cache_util.h baum.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h: + +/usr/include/limits.h: + +/usr/include/bits/posix1_lim.h: + +/usr/include/bits/local_lim.h: + +/usr/include/linux/limits.h: + +/usr/include/bits/posix2_lim.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +globals.h: + +/usr/include/assert.h: + +../H/fold_vars.h: + +../H/energy_const.h: + +../H/utils.h: + +./config.h: + +cache_util.h: + +baum.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/AUTHORS b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/AUTHORS new file mode 100755 index 00000000..bfcbc6ad --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/AUTHORS @@ -0,0 +1,2 @@ +Christoph Flamm and +Ivo L. Hofacker diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/COPYING b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/COPYING new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/ChangeLog b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/ChangeLog new file mode 100755 index 00000000..68c4b46a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/ChangeLog @@ -0,0 +1,3 @@ +2001-08-01 Christoph Flamm, Ivo L. Hofacker + + *Kinfold: initial version diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/Makefile new file mode 100755 index 00000000..b211a764 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/Makefile @@ -0,0 +1,286 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# Example/Makefile. 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install-exec \ + install-exec-am install-info install-info-am install-man \ + install-strip installcheck installcheck-am installdirs \ + maintainer-clean maintainer-clean-generic mostlyclean \ + mostlyclean-generic pdf pdf-am ps ps-am uninstall uninstall-am \ + uninstall-info-am + +# Tell versions [3.59,3.63) of GNU make to not export all variables. +# Otherwise a system limit (for SysV at least) may be exceeded. +.NOEXPORT: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/README b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/README new file mode 100755 index 00000000..518bbc09 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/README @@ -0,0 +1,55 @@ +---------- +Folding Modes: + +(1) default mode: + start structure is open chain + stop structure is minimum free enegy structure + example: hairpin.log, traj + ../Kinfold --log hpin --num 10 <./hpin.in>& traj + +(2) multi-stop mode: + start structure is open chain + stop structure(s) are 2nd and following lines in hpin.in + example: hairpin.e.log, traj.e + ../Kinfold --stop --log hpin.e --num 10 <./hpin.in>& traj.e + +(3) refolding mode: + start structure is 2nd line in hpin.in + stop structure(s) are 3rd and following lines in hpin.in + example: hairpin.ae.log, traj.ae + ../Kinfold --start --stop --log hpin.ae --num 10 <./hpin.in>& traj.ae + +if you don't want to log the trajectories use option --silent +(trajectory files can get petty huge) + +---------- +Output: + +(A) log files (on each line you find): + randon seed + stop-structure-label or O ( for didn't reach stop-structure(s) ) + first passage time + stop-structure if stop-structure-label equals O + +(B) trajectory files (on each line you find): + structure + energy + time + number of neighbours of structure (only with --verbose) + code for the move (only with --verbose) + (i=base pair insert move, + d=base pair delete move, + s,S=base pair shift move, + I=base pair double insert move (only with --noLP) + D=base pair double delete move (only with --noLP) + ) + code for type of structure (only with --verbose) + (1=strict local minimum, + 2=degenerate local minimum, + 0=anything else + ) + stop-structure-label or O ( for didn't reach stop-structure(s) ) + +---------- +canonical example: hpin.nolp, traj.nolp + ../Kinfold --verbose --noLP --num 10 --log hpin.nolp < ./hpin.in > traj.nolp diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.ae.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.ae.log new file mode 100755 index 00000000..89bb1cd3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.ae.log @@ -0,0 +1,20 @@ +#< +#Date: Thu Aug 2 15:09:44 2001 +#EnergyModel: dangle=2 Temp=37.0 logML=logarithmic Par=VRNA-1.4 +#MoveSet: noShift=off noLP=off +#Simulation: num=10 time=500.00 seed=clock fpt=on mc=Kawasaki +#Output: log=hairpin.ae silent=on lmin=off cut=20.00 +#ACUGAUCGUAGUCAC +#((((....))))... ( 0.40) +#..((((....)))). ( -0.60) X01 +(20760 15209 5246) X01 67.304 +(45270 55184 46987) X01 89.090 +(53914 48671 9491) X01 8.332 +(44432 62476 30554) X01 21.474 +(21206 16128 4429) X01 31.761 +( 5998 36361 17232) X01 33.787 +(35376 54746 29922) X01 4.436 +(51998 14938 13352) X01 38.070 +(17648 21853 64886) X01 51.808 +(16304 9322 17404) X01 30.137 +(46698 42323 39623) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.e.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.e.log new file mode 100755 index 00000000..14aca206 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.e.log @@ -0,0 +1,21 @@ +#< +#Date: Thu Aug 2 15:12:23 2001 +#EnergyModel: dangle=2 Temp=37.0 logML=logarithmic Par=VRNA-1.4 +#MoveSet: noShift=off noLP=off +#Simulation: num=10 time=500.00 seed=clock fpt=on mc=Kawasaki +#Output: log=hairpin.e silent=on lmin=off cut=20.00 +#ACUGAUCGUAGUCAC +#............... ( 0.00) +#..((((....)))). ( -0.60) X01 +#((((....))))... ( 0.40) X02 +(20919 15209 5246) X01 9.495 +(37503 34287 60895) X01 5.325 +(32207 13446 53388) X01 6.008 +(45167 5229 23791) X02 4.194 +(45433 53919 17806) X02 5.419 +(10205 8134 35980) X01 32.380 +(36817 5241 15865) X01 4.066 +(22891 28285 5106) X02 9.916 +(11239 25108 29130) X01 6.766 +(29917 23269 27183) X01 11.207 +(11597 13711 6518) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.in new file mode 100755 index 00000000..18ef5862 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.in @@ -0,0 +1,3 @@ +ACUGAUCGUAGUCAC +((((....))))... +..((((....)))). diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.log new file mode 100755 index 00000000..5b22424f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.log @@ -0,0 +1,20 @@ +#< +#Date: Thu Aug 2 15:07:51 2001 +#EnergyModel: dangle=2 Temp=37.0 logML=logarithmic Par=VRNA-1.4 +#MoveSet: noShift=off noLP=off +#Simulation: num=10 time=500.00 seed=clock fpt=on mc=Kawasaki +#Output: log=hairpin silent=on lmin=off cut=20.00 +#ACUGAUCGUAGUCAC +#............... ( 0.00) +#..((((....)))). ( -0.60) X01 +(20647 15209 5246) X01 3.761 +(45273 46965 58195) X01 59.663 +(38349 38236 54635) X01 2.485 +( 2807 18778 20846) X01 8.455 +( 9813 63338 21421) X01 7.325 +(36623 13209 39161) X01 7.609 +(15011 38369 16622) X01 6.431 +(38685 28037 30315) X01 8.799 +(59813 28723 56993) X01 3.397 +(12419 11904 47612) X01 29.864 +(41943 21469 46941) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.nolp.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.nolp.log new file mode 100755 index 00000000..4e15c052 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/hpin.nolp.log @@ -0,0 +1,20 @@ +#< +#Date: Thu Aug 2 16:24:42 2001 +#EnergyModel: dangle=2 Temp=37.0 logML=logarithmic Par=VRNA-1.4 +#MoveSet: noShift=off noLP=on +#Simulation: num=10 time=500.00 seed=clock fpt=on mc=Kawasaki +#Output: log=hpin.nolp silent=off lmin=off cut=20.00 +#ACUGAUCGUAGUCAC +#............... ( 0.00) +#..((((....)))). ( -0.60) X01 +(25258 15209 5246) X01 2.860 +(44730 44944 54555) X01 4.393 +(45786 38897 9635) X01 5.149 +( 1138 2575 3872) X01 1.976 +(18170 22215 30745) X01 11.294 +(15062 36074 3444) X01 25.262 +(45366 51780 48872) X01 5.836 +(47174 49996 2611) X01 4.510 +(36794 62744 9691) X01 14.810 +(48262 52565 918) X01 17.438 +(54706 34016 15011) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/traj b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/traj new file mode 100755 index 00000000..74be8538 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/traj @@ -0,0 +1,312 @@ +............... 0.00 0.314 24 i 1 +.......(....).. 2.10 0.516 10 d 0 +............... 0.00 0.903 24 i 1 +.(.....)....... 3.10 0.934 10 d 0 +............... 0.00 1.603 24 i 1 +....(......)... 4.80 1.606 11 d 0 +............... 0.00 1.983 24 i 1 +.......(....).. 2.10 1.999 10 d 0 +............... 0.00 2.325 24 i 1 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+............... 0.00 0.146 24 i 1 +.......(....).. 2.10 0.227 10 s 0 +.......(......) 3.20 0.312 9 d 0 +............... 0.00 2.574 24 i 1 +.......(....).. 2.10 2.654 10 d 0 +............... 0.00 3.356 24 i 1 +.......(......) 3.20 3.413 9 d 0 +............... 0.00 4.742 24 i 1 +...(........).. 1.80 4.921 12 d 0 +............... 0.00 6.128 24 i 1 +.......(....).. 2.10 6.463 10 s 0 +.......(......) 3.20 6.478 9 d 0 +............... 0.00 7.229 24 i 1 +...(........).. 1.80 7.262 12 S 0 +.......(....).. 2.10 7.291 10 d 0 +............... 0.00 7.603 24 i 1 +...(........).. 1.80 7.707 12 i 0 +..((........)). 1.30 7.752 11 i 0 +..(((......))). 0.20 8.740 8 d 0 +..((........)). 1.30 8.940 11 i 0 +..(((......))). 0.20 9.363 8 d 0 +...((......)).. 0.70 9.382 9 i 0 +...(((....))).. -0.10 9.435 7 i 0 +..((((....)))). -0.60 11.207 6 _ 1 X1 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/Example/traj.nolp 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17.438 2 _ 1 X1 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/INSTALL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/INSTALL new file mode 100755 index 00000000..b42a17ac --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/INSTALL @@ -0,0 +1,182 @@ +Basic Installation +================== + + These are generic installation instructions. + + The `configure' shell script attempts to guess correct values for +various system-dependent variables used during compilation. It uses +those values to create a `Makefile' in each directory of the package. +It may also create one or more `.h' files containing system-dependent +definitions. Finally, it creates a shell script `config.status' that +you can run in the future to recreate the current configuration, a file +`config.cache' that saves the results of its tests to speed up +reconfiguring, and a file `config.log' containing compiler output +(useful mainly for debugging `configure'). + + If you need to do unusual things to compile the package, please try +to figure out how `configure' could check whether to do them, and mail +diffs or instructions to the address given in the `README' so they can +be considered for the next release. If at some point `config.cache' +contains results you don't want to keep, you may remove or edit it. + + The file `configure.in' is used to create `configure' by a program +called `autoconf'. You only need `configure.in' if you want to change +it or regenerate `configure' using a newer version of `autoconf'. + +The simplest way to compile this package is: + + 1. `cd' to the directory containing the package's source code and type + `./configure' to configure the package for your system. If you're + using `csh' on an old version of System V, you might need to type + `sh ./configure' instead to prevent `csh' from trying to execute + `configure' itself. + + Running `configure' takes awhile. While running, it prints some + messages telling which features it is checking for. + + 2. Type `make' to compile the package. + + 3. Optionally, type `make check' to run any self-tests that come with + the package. + + 4. Type `make install' to install the programs and any data files and + documentation. + + 5. You can remove the program binaries and object files from the + source code directory by typing `make clean'. To also remove the + files that `configure' created (so you can compile the package for + a different kind of computer), type `make distclean'. There is + also a `make maintainer-clean' target, but that is intended mainly + for the package's developers. If you use it, you may have to get + all sorts of other programs in order to regenerate files that came + with the distribution. + +Compilers and Options +===================== + + Some systems require unusual options for compilation or linking that +the `configure' script does not know about. You can give `configure' +initial values for variables by setting them in the environment. Using +a Bourne-compatible shell, you can do that on the command line like +this: + CC=c89 CFLAGS=-O2 LIBS=-lposix ./configure + +Or on systems that have the `env' program, you can do it like this: + env CPPFLAGS=-I/usr/local/include LDFLAGS=-s ./configure + +Compiling For Multiple Architectures +==================================== + + You can compile the package for more than one kind of computer at the +same time, by placing the object files for each architecture in their +own directory. To do this, you must use a version of `make' that +supports the `VPATH' variable, such as GNU `make'. `cd' to the +directory where you want the object files and executables to go and run +the `configure' script. `configure' automatically checks for the +source code in the directory that `configure' is in and in `..'. + + If you have to use a `make' that does not supports the `VPATH' +variable, you have to compile the package for one architecture at a time +in the source code directory. After you have installed the package for +one architecture, use `make distclean' before reconfiguring for another +architecture. + +Installation Names +================== + + By default, `make install' will install the package's files in +`/usr/local/bin', `/usr/local/man', etc. You can specify an +installation prefix other than `/usr/local' by giving `configure' the +option `--prefix=PATH'. + + You can specify separate installation prefixes for +architecture-specific files and architecture-independent files. If you +give `configure' the option `--exec-prefix=PATH', the package will use +PATH as the prefix for installing programs and libraries. +Documentation and other data files will still use the regular prefix. + + In addition, if you use an unusual directory layout you can give +options like `--bindir=PATH' to specify different values for particular +kinds of files. Run `configure --help' for a list of the directories +you can set and what kinds of files go in them. + + If the package supports it, you can cause programs to be installed +with an extra prefix or suffix on their names by giving `configure' the +option `--program-prefix=PREFIX' or `--program-suffix=SUFFIX'. + +Optional Features +================= + + Some packages pay attention to `--enable-FEATURE' options to +`configure', where FEATURE indicates an optional part of the package. +They may also pay attention to `--with-PACKAGE' options, where PACKAGE +is something like `gnu-as' or `x' (for the X Window System). The +`README' should mention any `--enable-' and `--with-' options that the +package recognizes. + + For packages that use the X Window System, `configure' can usually +find the X include and library files automatically, but if it doesn't, +you can use the `configure' options `--x-includes=DIR' and +`--x-libraries=DIR' to specify their locations. + +Specifying the System Type +========================== + + There may be some features `configure' can not figure out +automatically, but needs to determine by the type of host the package +will run on. Usually `configure' can figure that out, but if it prints +a message saying it can not guess the host type, give it the +`--host=TYPE' option. TYPE can either be a short name for the system +type, such as `sun4', or a canonical name with three fields: + CPU-COMPANY-SYSTEM + +See the file `config.sub' for the possible values of each field. If +`config.sub' isn't included in this package, then this package doesn't +need to know the host type. + + If you are building compiler tools for cross-compiling, you can also +use the `--target=TYPE' option to select the type of system they will +produce code for and the `--build=TYPE' option to select the type of +system on which you are compiling the package. + +Sharing Defaults +================ + + If you want to set default values for `configure' scripts to share, +you can create a site shell script called `config.site' that gives +default values for variables like `CC', `cache_file', and `prefix'. +`configure' looks for `PREFIX/share/config.site' if it exists, then +`PREFIX/etc/config.site' if it exists. Or, you can set the +`CONFIG_SITE' environment variable to the location of the site script. +A warning: not all `configure' scripts look for a site script. + +Operation Controls +================== + + `configure' recognizes the following options to control how it +operates. + +`--cache-file=FILE' + Use and save the results of the tests in FILE instead of + `./config.cache'. Set FILE to `/dev/null' to disable caching, for + debugging `configure'. + +`--help' + Print a summary of the options to `configure', and exit. + +`--quiet' +`--silent' +`-q' + Do not print messages saying which checks are being made. To + suppress all normal output, redirect it to `/dev/null' (any error + messages will still be shown). + +`--srcdir=DIR' + Look for the package's source code in directory DIR. 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Hofacker + + for the energy evaluation Kinfold uses routines from + the Vienna-RNA-Package Version 1.4. + you can download the source code for Vienna-RNA-Package from + http://www.tbi.univie.ac.at/~ivo/RNA/ + +Comments are welcome. + + - Christoph Flamm, diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/acinclude.m4 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/acinclude.m4 new file mode 100755 index 00000000..01c514d0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/acinclude.m4 @@ -0,0 +1,53 @@ +dnl -*-autoconf-*- + +AC_DEFUN([AC_PATH_VRNA], +[AC_MSG_CHECKING([for ViennaRNA package]) +if test -z "$ac_VRNA_includes"; then + for ac_dir in \ + ../H \ + /usr/local/include/ViennaRNA \ + /usr/local/include \ + /usr/include/ViennaRNA \ + /usr/local/ViennaRNA/H \ + /usr/local/share/ViennaRNA/include \ + /opt/ViennaRNA/include \ + ;\ + do + if test -r "$ac_dir/part_func.h"; then + ac_VRNA_includes=$ac_dir + break + fi + done +fi +if test $ac_VRNA_includes; then + CPPFLAGS="$CPPFLAGS -I$ac_VRNA_includes" +fi + +if [[ -d ../lib ] && [ "$ac_VRNA_includes" = "../H" ]]; then + ac_VRNA_lib=../lib +fi + +if test -z "$ac_VRNA_lib"; then +for ac_dir in `echo "$ac_VRNA_includes" | sed -e s/include/lib/ -e s/H$/lib/` \ + /usr/local/lib \ + ; \ +do + for ac_extension in a so sl; do + if test -r $ac_dir/libRNA.$ac_extension; then + ac_VRNA_lib=$ac_dir + break 2 + fi + done +done +fi # $ac_VRNA_lib = NO +if test $ac_VRNA_lib; then + LDFLAGS="-L$ac_VRNA_lib $LDFLAGS" +fi +AC_MSG_RESULT([ headers in "$ac_VRNA_includes" and library... "$ac_VRNA_lib"]) + +dnl So far we've only set up paths, we could also check for +dnl usability of headers and library like so +dnl AC_CHECK_HEADER(part_func.h, [], +dnl [AC_MSG_ERROR([Cannot find ViennaRNA headers])]) +dnl AC_CHECK_LIB(RNA, fold) +]) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/aclocal.m4 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/aclocal.m4 new file mode 100755 index 00000000..74c85d4f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/aclocal.m4 @@ -0,0 +1,891 @@ +# generated automatically by aclocal 1.9.5 -*- Autoconf -*- + +# Copyright (C) 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, +# 2005 Free Software Foundation, Inc. +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + +# Copyright (C) 2002, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# AM_AUTOMAKE_VERSION(VERSION) +# ---------------------------- +# Automake X.Y traces this macro to ensure aclocal.m4 has been +# generated from the m4 files accompanying Automake X.Y. +AC_DEFUN([AM_AUTOMAKE_VERSION], [am__api_version="1.9"]) + +# AM_SET_CURRENT_AUTOMAKE_VERSION +# ------------------------------- +# Call AM_AUTOMAKE_VERSION so it can be traced. +# This function is AC_REQUIREd by AC_INIT_AUTOMAKE. +AC_DEFUN([AM_SET_CURRENT_AUTOMAKE_VERSION], + [AM_AUTOMAKE_VERSION([1.9.5])]) + +# AM_AUX_DIR_EXPAND -*- Autoconf -*- + +# Copyright (C) 2001, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# For projects using AC_CONFIG_AUX_DIR([foo]), Autoconf sets +# $ac_aux_dir to `$srcdir/foo'. 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We just wanted to have am__tar + # and am__untar set. + test -n "${am_cv_prog_tar_$1}" && break + + # tar/untar a dummy directory, and stop if the command works + rm -rf conftest.dir + mkdir conftest.dir + echo GrepMe > conftest.dir/file + AM_RUN_LOG([tardir=conftest.dir && eval $am__tar_ >conftest.tar]) + rm -rf conftest.dir + if test -s conftest.tar; then + AM_RUN_LOG([$am__untar /dev/null 2>&1 && break + fi +done +rm -rf conftest.dir + +AC_CACHE_VAL([am_cv_prog_tar_$1], [am_cv_prog_tar_$1=$_am_tool]) +AC_MSG_RESULT([$am_cv_prog_tar_$1])]) +AC_SUBST([am__tar]) +AC_SUBST([am__untar]) +]) # _AM_PROG_TAR + +m4_include([acinclude.m4]) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/baum.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/baum.c new file mode 100755 index 00000000..8e9a451d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/baum.c @@ -0,0 +1,726 @@ +/* + Last changed Time-stamp: <2006-01-16 11:27:31 ivo> + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: baum.c,v 1.5 2006/01/16 10:37:47 ivo Exp $ +*/ + +#include +#include +#include +#include +#include "fold_vars.h" +#include "fold.h" +#include "utils.h" +#include "pair_mat.h" +#include "nachbar.h" +#include "globals.h" + + +#define MYTURN 4 +#define ORDER(x,y) if ((x)->nummer>(y)->nummer) {tempb=x; x=y; y=tempb;} + +/* item of structure ringlist */ +typedef struct _baum { + int nummer; /* number of base in sequence */ + char typ; /* 'r' virtualroot, 'p' or 'q' paired, 'u' unpaired */ + unsigned short base; /* 0<->unknown, 1<->A, 2<->C, 3<->G, 4<->U */ + struct _baum *up; + struct _baum *next; + struct _baum *prev; + struct _baum *down; +} baum; + +static char UNUSED rcsid[]="$Id: baum.c,v 1.5 2006/01/16 10:37:47 ivo Exp $"; +static int poListop = 0; /* polist counter = no_of_bp */ +static short *pairList; +static short *typeList; +static short *aliasList; +static baum *rl; /* ringlist */ +static baum *wurzl; /* virtualroot of ringlist-tree */ +static baum **poList; /* post order list of bp's */ +static char **ptype; + +static int comp_struc(const void *A, const void *B); +extern int energy_of_struct_pt (char *string, + short * ptable, short *s, short *s1); +/* PUBLIC FUNCTIONES */ +void ini_or_reset_rl (void); +void move_it (void); +void update_tree (int i, int j); +void clean_up_rl (void); + +/* PRIVATE FUNCTIONES */ +static void ini_ringlist(void); +static void reset_ringlist(void); +static void struc2tree (char *struc); +static void close_bp (baum *i, baum *j); +static void open_bp (baum *i); +static void make_poList (baum *root); +static void inb (baum *root); +static void inb_nolp (baum *root); +static void dnb (baum *rli); +static void dnb_nolp (baum *rli); +static void fnb (baum *rli); +static void make_ptypes(const short *S); +/* debugging tool(s) */ +#if 0 +static void rl_status(void); +#endif + +/* convert structure in bracked-dot-notation to a ringlist-tree */ +static void struc2tree(char *struc) { + char* struc_copy; + int ipos, jpos, balance = 0; + baum *rli, *rlj; + + struc_copy = (char *)calloc(GSV.len+1, sizeof(char)); + assert(struc_copy); + strcpy(struc_copy,struc); + + for (ipos = 0; ipos < GSV.len; ipos++) { + if (struc_copy[ipos] == ')') { + jpos = ipos; + struc_copy[ipos] = '.'; + balance++; + while (struc_copy[--ipos] != '('); + struc_copy[ipos] = '.'; + balance--; + rli = &rl[ipos]; + rlj = &rl[jpos]; + close_bp(rli, rlj); + } + } + + if (balance) { + fprintf(stderr, + "struc2tree(): start structure is not balanced !\n%s\n%s\n", + GAV.farbe, struc); + exit(1); + } + + poListop = 1; + make_poList(NULL); + GSV.currE = GSV.startE = + (float )energy_of_struct_pt(GAV.farbe, + pairList, typeList, aliasList) / 100.0; + free(struc_copy); +} + +/**/ +static void ini_ringlist(void) { + int i; + + /* needed by function energy_of_struct_pt() from Vienna-RNA-1.4 */ + pairList = (short *)calloc(GSV.len + 2, sizeof(short)); + assert(pairList != NULL); + typeList = (short *)calloc(GSV.len + 2, sizeof(short)); + assert(typeList != NULL); + aliasList = (short *)calloc(GSV.len + 2, sizeof(short)); + assert(aliasList != NULL); + pairList[0] = typeList[0] = aliasList[0] = GSV.len; + ptype = (char **)calloc(GSV.len + 2, sizeof(char *)); + assert(ptype != NULL); + for (i=0; i<=GSV.len; i++) { + ptype[i] = (char*)calloc(GSV.len + 2, sizeof(char)); + assert(ptype[i] != NULL); + } + + /* allocate virtual root */ + wurzl = (baum *)calloc(1, sizeof(baum)); + assert(wurzl != NULL); + /* allocate ringList */ + rl = (baum *)calloc(GSV.len+1, sizeof(baum)); + assert(rl != NULL); + /* allocate PostOrderList */ + poList = (baum **)calloc(GSV.len+2, sizeof(baum *)); + assert(poList != NULL); + + /* initialize virtualroot */ + wurzl->typ = 'r'; + wurzl->nummer = -1; + /* connect virtualroot to ringlist-tree in down direction */ + wurzl->down = &rl[GSV.len]; + /* initialize post-order list */ + poList[poListop++] = wurzl; + + make_pair_matrix(); + + /* initialize rest of ringlist-tree */ + for(i = 0; i < GSV.len; i++) { + int c; + GAV.currform[i] = '.'; + GAV.prevform[i] = 'x'; + pairList[i+1] = 0; + rl[i].typ = 'u'; + /* decode base to numeric value */ + c = encode_char(GAV.farbe[i]); + rl[i].base = typeList[i+1] = c; + aliasList[i+1] = alias[typeList[i+1]]; + /* astablish links for node of the ringlist-tree */ + rl[i].nummer = i; + rl[i].next = &rl[i+1]; + rl[i].prev = ((i == 0) ? &rl[GSV.len] : &rl[i-1]); + rl[i].up = rl[i].down = NULL; + } + GAV.currform[GSV.len] = GAV.prevform[GSV.len] = '\0'; + make_ptypes(aliasList); + + rl[i].nummer = i; + rl[i].base = 0; + /* make ringlist circular in next, prev direction */ + rl[i].next = &rl[0]; + rl[i].prev = &rl[i-1]; + /* make virtual basepair for virtualroot */ + rl[i].up = wurzl; + rl[i].typ = 'x'; +} + +/**/ +void ini_or_reset_rl(void) { + + /* if there is no ringList-tree make a new one */ + if (wurzl == NULL) { + ini_ringlist(); + + /* start structure */ + struc2tree(GAV.startform); + GSV.currE = GSV.startE = energy_of_struct(GAV.farbe, GAV.startform); + + + /* stop structure(s) */ + if ( GTV.stop ) { + int i; + + qsort(GAV.stopform, GSV.maxS, sizeof(char *), comp_struc); + for (i = 0; i< GSV.maxS; i++) + GAV.sE[i] = energy_of_struct(GAV.farbe_full, GAV.stopform[i]); + } + else { + if(GTV.noLP) + noLonelyPairs=1; + initialize_fold(GSV.len); + /* fold sequence to get Minimum free energy structure (Mfe) */ + GAV.sE[0] = fold(GAV.farbe_full, GAV.stopform[0]); + free_arrays(); + /* revaluate energy of Mfe (maye differ if --logML=logarthmic */ + GAV.sE[0] = energy_of_struct(GAV.farbe_full, GAV.stopform[0]); + } + GSV.stopE = GAV.sE[0]; + ini_nbList(strlen(GAV.farbe_full)*strlen(GAV.farbe_full)); + } + else { + /* reset ringlist-tree to start conditions */ + reset_ringlist(); + if(GTV.start) struc2tree(GAV.startform); + else { + GSV.currE = GSV.startE; + poListop = 1; + } + } +} + +/**/ +static void reset_ringlist(void) { + int i; + + for(i = 0; i < GSV.len; i++) { + GAV.currform[i] = '.'; + GAV.prevform[i] = 'x'; + pairList[i+1] = 0; + rl[i].typ = 'u'; + rl[i].next = &rl[i + 1]; + rl[i].prev = ((i == 0) ? &rl[GSV.len] : &rl[i - 1]); + rl[i].up = rl[i].down = NULL; + } + rl[i].next = &rl[0]; + rl[i].prev = &rl[i-1]; + rl[i].up = wurzl; +} + +/* update ringlist-tree */ +void update_tree(int i, int j) { + + baum *rli, *rlj, *tempb; + + if ( abs(i) < GSV.len) { /* >> single basepair move */ + if ((i > 0) && (j > 0)) { /* insert */ + rli = &rl[i-1]; + rlj = &rl[j-1]; + close_bp(rli, rlj); + } + else if ((i < 0)&&(j < 0)) { /* delete */ + i = -i; + rli = &rl[i-1]; + open_bp(rli); + } + else { /* shift */ + if (i > 0) { /* i remains the same, j shifts */ + j=-j; + rli=&rl[i-1]; + rlj=&rl[j-1]; + open_bp(rli); + ORDER(rli, rlj); + close_bp(rli, rlj); + } + else { /* j remains the same, i shifts */ + baum *old_rli; + i = -i; + rli = &rl[i-1]; + rlj = &rl[j-1]; + old_rli = rlj->up; + open_bp(old_rli); + ORDER(rli, rlj); + close_bp(rli, rlj); + } + } + } /* << single basepair move */ + else { /* >> double basepair move */ + if ((i > 0) && (j > 0)) { /* insert */ + rli = &rl[i-GSV.len-2]; + rlj = &rl[j-GSV.len-2]; + close_bp(rli->next, rlj->prev); + close_bp(rli, rlj); + } + else if ((i < 0)&&(j < 0)) { /* delete */ + i = -i; + rli = &rl[i-GSV.len-2]; + open_bp(rli); + open_bp(rli->next); + } + } /* << double basepair move */ + + poListop = 1; + make_poList(NULL); +} + +/* open a particular base pair */ +void open_bp(baum *i) { + + baum *in; /* points to i->next */ + + /* change string representation */ + GAV.currform[i->nummer] = '.'; + GAV.currform[i->down->nummer] = '.'; + + /* change pairtable representation */ + pairList[1 + i->nummer] = 0; + pairList[1 + i->down->nummer] = 0; + + /* change tree representation */ + in = i->next; + i->typ = 'u'; + i->down->typ = 'u'; + i->next = i->down->next; + i->next->prev = i; + in->prev = i->down; + i->down->next = in; + i->down = in->prev->up = NULL; +} + +/* close a particular base pair */ +void close_bp (baum *i, baum *j) { + + baum *jn; /* points to j->next */ + + /* change string representation */ + GAV.currform[i->nummer] = '('; + GAV.currform[j->nummer] = ')'; + + /* change pairtable representation */ + pairList[1 + i->nummer] = 1+ j->nummer; + pairList[1 + j->nummer] = 1 + i->nummer; + + /* change tree representation */ + jn = j->next; + i->typ = 'p'; + j->typ = 'q'; + i->down = j; + j->up = i; + i->next->prev = j; + j->next->prev = i; + j->next = i->next; + i->next = jn; +} + +/* for a given tree, generate postorder-list */ +static void make_poList (baum *root) { + + baum *stop, *rli; + + if (!root) root = wurzl; + stop = root->down; + + /* foreach base in ringlist ... */ + for (rli = stop->next; rli != stop; rli = rli->next) { + /* ... explore subtee if bp found */ + if (rli->typ == 'p') { + /* fprintf(stderr, "%d >%d<\n", poListop, rli->nummer); */ + poList[poListop++] = rli; + if ( poListop > GSV.len+1 ) { + fprintf(stderr, "Something went wrong in make_poList()\n"); + exit(1); + } + make_poList(rli); + } + } + return; +} + +/* for a given ringlist, generate all structures + with one additional basepair */ +static void inb(baum *root) { + + int EoT = 0; + baum *stop,*rli,*rlj; + + stop=root->down; + /* loop ringlist over all possible i positions */ + for(rli=stop->next;rli!=stop;rli=rli->next){ + /* potential i-position is already paired */ + if(rli->typ=='p') continue; + /* loop ringlist over all possible j positions */ + for(rlj=rli->next;rlj!=stop;rlj=rlj->next){ + /* base pair must enclose at least 3 bases */ + if(rlj->nummer - rli->nummer < MYTURN) continue; + /* potential j-position is already paired */ + if(rlj->typ=='p') continue; + /* if i-j can form a base pair ... */ + if(ptype[rli->nummer][rlj->nummer]){ + /* close the base bair and ... */ + close_bp(rli,rlj); + /* ... evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* open the base pair again... */ + open_bp(rli); + /* ... and put the move and the enegy + of the structure into the neighbour list */ + update_nbList(1 + rli->nummer, 1 + rlj->nummer, EoT); + } + } + } +} + +/* for a given ringlist, generate all structures (canonical) + with one additional base pair (BUT WITHOUT ISOLATED BASE PAIRS) */ +static void inb_nolp(baum *root) { + + int EoT = 0; + baum *stop, *rli, *rlj; + + stop = root->down; + /* loop ringlist over all possible i positions */ + for (rli=stop->next;rli!=stop;rli=rli->next) { + /* potential i-position is already paired */ + if (rli->typ=='p') continue; + /* loop ringlist over all possible j positions */ + for (rlj=rli->next;rlj!=stop;rlj=rlj->next) { + /* base pair must enclose at least 3 bases */ + if (rlj->nummer - rli->nummer < MYTURN) continue; + /* potential j-position is already paired */ + if (rlj->typ=='p') continue; + /* if i-j can form a base pair ... */ + if (ptype[rli->nummer][rlj->nummer]) { + /* ... and extends a helix ... */ + if (((rli->prev==stop && rlj->next==stop) && stop->typ != 'x') || + (rli->next == rlj->prev)) { + /* ... close the base bair and ... */ + close_bp(rli,rlj); + /* ... evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* open the base pair again... */ + open_bp(rli); + /* ... and put the move and the enegy + of the structure into the neighbour list */ + update_nbList(1 + rli->nummer, 1 + rlj->nummer, EoT); + } + /* if double insertion is possible ... */ + else if ((rlj->nummer - rli->nummer >= MYTURN+2)&& + (rli->next->typ != 'p' && rlj->prev->typ != 'p') && + (rli->next->next != rlj->prev->prev) && + (ptype[rli->next->nummer][rlj->prev->nummer])) { + /* close the two base bair and ... */ + close_bp(rli->next, rlj->prev); + close_bp(rli, rlj); + /* ... evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* open the two base pair again ... */ + open_bp(rli); + open_bp(rli->next); + /* ... and put the move and the enegy + of the structure into the neighbour list */ + update_nbList(1+rli->nummer+GSV.len+1, 1+rlj->nummer+GSV.len+1, EoT); + } + } + } + } +} + +/* for a given ringlist, generate all structures + with one less base pair */ +static void dnb(baum *rli){ + + int EoT = 0; + baum *rlj; + + rlj=rli->down; + open_bp(rli); + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + close_bp(rli,rlj); + update_nbList(-(1 + rli->nummer), -(1 + rlj->nummer), EoT); +} + +/* for a given ringlist, generate all structures (canonical) + with one less base pair (BUT WITHOUT ISOLATED BASE PAIRS) */ +static void dnb_nolp(baum *rli) { + + int EoT = 0; + baum *rlj; + baum *rlin = NULL; /* pointers to following pair in helix, if any */ + baum *rljn = NULL; + baum *rlip = NULL; /* pointers to preceding pair in helix, if any */ + baum *rljp = NULL; + + rlj = rli->down; + + /* immediate interior base pair ? */ + if (rlj->next == rlj->prev) { + rlin = rlj->next; + rljn = rlin->down; + } + + /* immediate exterior base pair and not virtualroot ? */ + if (rli->prev == rli->next && rli->next->typ != 'x') { + rlip = rli->next->up; + rljp = rli->next; + } + + /* double delete ? */ + if (rlip==NULL && rlin && rljn->next != rljn->prev ) { + /* open the two base pairs ... */ + open_bp(rli); + open_bp(rlin); + /* ... evaluate energy of the structure ... */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* ... and put the move and the enegy + of the structure into the neighbour list ... */ + update_nbList(-(1+rli->nummer+GSV.len+1),-(1+rlj->nummer+GSV.len+1), EoT); + /* ... and close the two base pairs again */ + close_bp(rlin, rljn); + close_bp(rli, rlj); + } else { /* single delete */ + /* the following will work only if boolean expr are shortcicuited */ + if (rlip==NULL || (rlip->prev == rlip->next && rlip->prev->typ != 'x')) + if (rlin ==NULL || (rljn->next == rljn->prev)) { + /* open the base pair ... */ + open_bp(rli); + /* ... evaluate energy of the structure ... */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* ... and put the move and the enegy + of the structure into the neighbour list ... */ + update_nbList(-(1 + rli->nummer),-(1 + rlj->nummer), EoT); + /* and close the base pair again */ + close_bp(rli, rlj); + } + } +} + +/* for a given ringlist, generate all structures + with one shifted base pair */ +static void fnb(baum *rli) { + + int EoT = 0, x; + baum *rlj, *stop, *help_rli, *help_rlj; + + stop = rli->down; + + /* examin interior loop of bp(ij); (.......) + i of j move -> <- */ + for (rlj = stop->next; rlj != stop; rlj = rlj->next) { + /* prevent shifting to paired position */ + if ((rlj->typ=='p')||(rlj->typ=='q')) continue; + /* j-position of base pair shifts to k position (ij)->(ik) inummer-rli->nummer >= MYTURN) + && (ptype[rli->nummer][rlj->nummer]) ) { + /* open original basepair */ + open_bp(rli); + /* close shifted version of original basepair */ + close_bp(rli, rlj); + /* evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* put the move and the enegy of the structure into the neighbour list */ + update_nbList(1+rli->nummer, -(1+rlj->nummer), EoT); + /* open shifted basepair */ + open_bp(rli); + /* restore original basepair */ + close_bp(rli, stop); + } + /* i-position of base pair shifts to position k (ij)->(kj) inummer-rlj->nummer >= MYTURN) + && (ptype[stop->nummer][rlj->nummer]) ) { + /* open original basepair */ + open_bp(rli); + /* close shifted version of original basepair */ + close_bp(rlj, stop); + /* evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* put the move and the enegy of the structure into the neighbour list */ + update_nbList(-(1 + rlj->nummer), 1 + stop->nummer, EoT); + /* open shifted basepair */ + open_bp(rlj); + /* restore original basepair */ + close_bp(rli, stop); + } + } + /* examin exterior loop of bp(ij); (.......) + i or j moves <- -> */ + for (rlj=rli->next;rlj!=rli;rlj=rlj->next) { + if ((rlj->typ=='p') || (rlj->typ=='q' ) || (rlj->typ=='x')) continue; + x=rlj->nummer-rli->nummer; + if (x<0) x=-x; + /* j-position of base pair shifts to position k */ + if ((x >= MYTURN) && (ptype[rli->nummer][rlj->nummer])) { + if (rli->nummernummer) { + help_rli=rli; + help_rlj=rlj; + } + else { + help_rli=rlj; + help_rlj=rli; + } + /* open original basepair */ + open_bp(rli); + /* close shifted version of original basepair */ + close_bp(help_rli,help_rlj); + /* evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* put the move and the enegy of the structure into the neighbour list */ + update_nbList(1 + rli->nummer, -(1 + rlj->nummer), EoT); + /* open shifted base pair */ + open_bp(help_rli); + /* restore original basepair */ + close_bp(rli,stop); + } + x = rlj->nummer-stop->nummer; + if (x < 0) x = -x; + /* i-position of base pair shifts to position k */ + if ((x >= MYTURN) && (ptype[stop->nummer][rlj->nummer])) { + if (stop->nummer < rlj->nummer) { + help_rli = stop; + help_rlj = rlj; + } + else { + help_rli = rlj; + help_rlj = stop; + } + /* open original basepair */ + open_bp(rli); + /* close shifted version of original basepair */ + close_bp(help_rli, help_rlj); + /* evaluate energy of the structure */ + EoT = energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList); + /* put the move and the enegy of the structure into the neighbour list */ + update_nbList(-(1 + rlj->nummer), 1 + stop->nummer, EoT); + /* open shifted basepair */ + open_bp(help_rli); + /* restore original basepair */ + close_bp(rli,stop); + } + } +} + +/* for a given tree (structure), + generate all neighbours according to moveset */ +void move_it (void) { + int i; + + GSV.currE = + energy_of_struct_pt(GAV.farbe, pairList, typeList, aliasList)/100.; + + if ( GTV.noLP ) { /* canonical neighbours only */ + for (i = 0; i < poListop; i++) { + /* canonical base pair insert neighbours */ + inb_nolp(poList[i]); + + if (i > 0) { /* virtual root bp should never be removed !!! */ + /* canonical base pair delete neighbours */ + dnb_nolp(poList[i]); + } + } + } + else { /* all neighbours */ + for (i = 0; i < poListop; i++) { + /* base pair insert neighbours */ + inb(poList[i]); + + if (i > 0) { /* virtual root bp should never be removed !!! */ + /* base pair delete neighbours */ + dnb(poList[i]); + /* base pair shift neighbours */ + if ( GTV.noShift == 0 ) fnb(poList[i]); + } + } + } +} + +/**/ +void clean_up_rl(void) { + + free(pairList); pairList=NULL; + free(typeList); typeList = NULL; + free(aliasList); aliasList = NULL; + free(rl); rl=NULL; + free(wurzl); wurzl=NULL; + free(poList); poList=NULL; poListop=0; +} + +/**/ +static int comp_struc(const void *A, const void *B) { + int aE, bE; + aE = (int)(100 * energy_of_struct(GAV.farbe_full, ((char **)A)[0])); + bE = (int)(100 * energy_of_struct(GAV.farbe_full, ((char **)B)[0])); + return (aE-bE); +} + +#if 0 +/**/ +static void rl_status(void) { + + int i; + + printf("\n%s\n%s\n", GAV.farbe, GAV.currform); + for (i=0; i <= GSV.len; i++) { + printf("%2d %c %c %2d %2d %2d %2d\n", + rl[i].nummer, + i == GSV.len ? 'X': GAV.farbe[i], + rl[i].typ, + rl[i].up==NULL?0:(rl[i].up)->nummer, + rl[i].down==NULL?0:(rl[i].down)->nummer, + (rl[i].prev)->nummer, + (rl[i].next)->nummer); + } + printf("---\n"); +} +#endif + +#define TURN MYTURN-1 +static void make_ptypes(const short *S) { + int n,i,j,k,l; + n=S[0]; + for (k=1; kn) continue; + type = pair[S[i]][S[j]]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: baum.h,v 1.1.1.1 2001/08/02 16:48:58 xtof Exp $ +*/ + +#ifndef BAUM_H +#define BAUM_H + +/* used in main.c */ +extern void ini_or_reset_rl(void); +extern void move_it(void); +extern void clean_up_rl(void); + +/* used in nachbar.c */ +extern void update_tree(int i,int j); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/baum.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/baum.o new file mode 100755 index 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+#include +#include +#include +#include +#include "utils.h" +#include "cache_util.h" + +/* + modify cache_f(), cache_comp() and the typedef of cache_entry + in cache_utils.h to suit your application +*/ + +/* PUBLIC FUNCTIONES */ +cache_entry *lookup_cache (char *x); +int write_cache (cache_entry *x); +/* void delete_cache (cache_entry *x); */ +void kill_cache(); +void initialize_cache(); + +/* PRIVATE FUNCTIONES */ +/* static int cache_comp(cache_entry *x, cache_entry *y); */ +static unsigned cache_f (char *x); + +/* #define CACHESIZE 67108864 -1 */ /* 2^26 -1 must be power of 2 -1 */ +/* #define CACHESIZE 33554432 -1 */ /* 2^25 -1 must be power of 2 -1 */ +/* #define CACHESIZE 16777216 -1 */ /* 2^24 -1 must be power of 2 -1 */ +/* #define CACHESIZE 4194304 -1 */ /* 2^22 -1 must be power of 2 -1 */ +#define CACHESIZE 1048576 -1 /* 2^20 -1 must be power of 2 -1 */ +/* #define CACHESIZE 262144 -1 */ /* 2^18 -1 must be power of 2 -1 */ +/* next is default */ +/* #define CACHESIZE 65536 -1 */ /* 2^16 -1 must be power of 2 -1 */ +/* #define CACHESIZE 16384 -1 */ /* 2^14 -1 must be power of 2 -1 */ +/* #define CACHESIZE 4096 -1 */ /* 2^12 -1 must be power of 2 -1 */ + +static cache_entry *cachetab[CACHESIZE+1]; +static char UNUSED rcsid[] ="$Id: cache.c,v 1.2 2005/02/16 17:00:48 ivo Exp $"; +unsigned long collisions=0; + +/* stolen from perl source */ +char coeff[] = { + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1, + 61,59,53,47,43,41,37,31,29,23,17,13,11,7,3,1}; + +/* key must not be longer than 128 */ +#pragma inline (cache_f) +unsigned cache_f(char *x) { + register char *s; + register int i; + register unsigned cache; + + s = x; + + for (i=0, cache = 0; + /* while */ *s; + s++, i++ , cache *= 5 ) { + cache += *s * coeff[i]; + } + + /* divide through CACHESIZE for normalization */ + return ((cache) & (CACHESIZE)); +} + + +/* returns NULL unless x is in the cache */ +cache_entry *lookup_cache (char *x) { + int cacheval; + cache_entry *c; + + cacheval=cache_f(x); + if ((c=cachetab[cacheval])) + if (strcmp(c->structure,x)==0) return c; + + return NULL; +} + +/* returns 1 if x already was in the cache */ +int write_cache (cache_entry *x) { + int cacheval; + cache_entry *c; + + cacheval=cache_f(x->structure); + if ((c=cachetab[cacheval])) { + free(c->structure); + free(c->neighbors); + free(c->rates); + free(c); + } + cachetab[cacheval]=x; + return 0; +} + +/**/ +void initialize_cache () { } + +/**/ +void kill_cache () { + int i; + + for (i=0;istructure); + free (cachetab[i]->neighbors); + free (cachetab[i]->rates); + free (cachetab[i]); + } + cachetab[i]=NULL; + } +} + +#if 0 +/**/ +static int cache_comp(cache_entry *x, cache_entry *y) { + return strcmp(((cache_entry *)x)->structure, ((cache_entry *)y)->structure); +} +#endif + +/* End of file */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/cache.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/cache.o new file mode 100755 index 0000000000000000000000000000000000000000..a3caf7a17a7bb10b6d7bc80d9fb5b78e9a5ac3c1 GIT binary patch literal 6236 zcmcgwdvH|M89#UL-P|Rc2gwE!An0m>B81&628AUsT^K*0bNaNX?Q4LfXh*WJ4j ztO^*w?raepAEO=ZwBz7(80}*U_GK-~47If{ooQ`#I@UpEpyG_}P)kQT>F+!DJJ}m` zrvLTK-2I*3_kHJg&iT&c-em8pwW~Ev6RK!J7ZoOiuio)=Nti39i+~E1I2ie5>D=bX z$D2y0KWIKYD(YW;g6#D#pXy&-|J_%$R}R;d>R;3koGPB%w*S5H@p@5u?am#iOCKM8 z>3RwrES(#>*itH9DHnaE9hXZVoj*Q4K3;A;7=-iSJ9bmaZa2z$$!I@+1&)KKN^jeq z$eU$^{=QtiQo6X~^x+ptXtLh@SIYN8?^3CFxon=_Qjsj3f#}?dV7b3lX_xzhs#4g$U%IOT zniik{iWkDHb((qy0^QYebNXSOq6CGg<^VLN06(^NfV!!Ya%4fHrhZqK%+D8}bH7V_A)3a;r4?k%UGZt!b48LQD?{ z6|A~zo~)qEEtO`=YIln?mLuxTHH zbinIr1=Ih~Nxv&#GfX`Jv*yzefq6`Qy<=QJjjHrKHSrp$j4ceW{v#NDUi~ftQ+8E# 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a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/cache_util.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/cache_util.h new file mode 100755 index 00000000..47ed1fa9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/cache_util.h @@ -0,0 +1,32 @@ +/* + Last changed Time-stamp: <2001-08-02 14:58:06 xtof> + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: cache_util.h,v 1.1.1.1 2001/08/02 16:48:58 xtof Exp $ +*/ + +#ifndef CACHE_UTIL_H +#define CACHE_UTIL_H + +#ifdef __GNUC__ +#define UNUSED __attribute__ ((unused)) +#else +#define UNUSED +#endif + +typedef struct { + char *structure; + int top; /* number of neighbors */ + int lmin; /* is a local minimum ? */ + double flux; /* sum of rates */ + double energy; /* energy of this structure */ + short *neighbors; + float *rates; +} cache_entry; + +extern cache_entry *lookup_cache (char *x); +extern int write_cache (cache_entry *x); +void kill_cache(void); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h new file mode 100755 index 00000000..fb0f7d73 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h @@ -0,0 +1,74 @@ +/* config.h. Generated by configure. */ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the header file. */ +#define HAVE_FOLD_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_INTTYPES_H 1 + +/* Define to 1 if you have the `m' library (-lm). */ +#define HAVE_LIBM 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_LIMITS_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_MEMORY_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDINT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDLIB_H 1 + +/* Define to 1 if you have the `strdup' function. */ +/* #undef HAVE_STRDUP */ + +/* Define to 1 if you have the header file. */ +#define HAVE_STRINGS_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STRING_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_STAT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_TIME_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_TYPES_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_UNISTD_H 1 + +/* Name of package */ +#define PACKAGE "kinfold" + +/* Define to the address where bug reports for this package should be sent. */ +#define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" + +/* Define to the full name of this package. */ +#define PACKAGE_NAME "Kinfold" + +/* Define to the full name and version of this package. */ +#define PACKAGE_STRING "Kinfold 1.0" + +/* Define to the one symbol short name of this package. */ +#define PACKAGE_TARNAME "kinfold" + +/* Define to the version of this package. */ +#define PACKAGE_VERSION "1.0" + +/* Define to 1 if you have the ANSI C header files. */ +/* #undef STDC_HEADERS */ + +/* Version number of package */ +#define VERSION "1.0" + +/* Define if using the dmalloc debugging malloc package */ +/* #undef WITH_DMALLOC */ + +/* Define to empty if `const' does not conform to ANSI C. */ +/* #undef const */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h.in new file mode 100755 index 00000000..7224bfa2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.h.in @@ -0,0 +1,73 @@ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the header file. */ +#undef HAVE_FOLD_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_INTTYPES_H + +/* Define to 1 if you have the `m' library (-lm). */ +#undef HAVE_LIBM + +/* Define to 1 if you have the header file. */ +#undef HAVE_LIMITS_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_MEMORY_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDINT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDLIB_H + +/* Define to 1 if you have the `strdup' function. */ +#undef HAVE_STRDUP + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRINGS_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRING_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_STAT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_TIME_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_TYPES_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_UNISTD_H + +/* Name of package */ +#undef PACKAGE + +/* Define to the address where bug reports for this package should be sent. */ +#undef PACKAGE_BUGREPORT + +/* Define to the full name of this package. */ +#undef PACKAGE_NAME + +/* Define to the full name and version of this package. */ +#undef PACKAGE_STRING + +/* Define to the one symbol short name of this package. */ +#undef PACKAGE_TARNAME + +/* Define to the version of this package. */ +#undef PACKAGE_VERSION + +/* Define to 1 if you have the ANSI C header files. */ +#undef STDC_HEADERS + +/* Version number of package */ +#undef VERSION + +/* Define if using the dmalloc debugging malloc package */ +#undef WITH_DMALLOC + +/* Define to empty if `const' does not conform to ANSI C. */ +#undef const diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.log new file mode 100755 index 00000000..5e2ff49c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.log @@ -0,0 +1,653 @@ +This file contains any messages produced by compilers while +running configure, to aid debugging if configure makes a mistake. + +It was created by Kinfold configure 1.0, which was +generated by GNU Autoconf 2.59. Invocation command line was + + $ ./configure --prefix=/usr/local --cache-file=/dev/null --srcdir=. + +## --------- ## +## Platform. ## +## --------- ## + +hostname = mcluster02 +uname -m = x86_64 +uname -r = 2.6.9-34.ELsmp +uname -s = Linux +uname -v = #1 SMP Fri Feb 24 16:56:28 EST 2006 + +/usr/bin/uname -p = unknown +/bin/uname -X = unknown + +/bin/arch = x86_64 +/usr/bin/arch -k = unknown +/usr/convex/getsysinfo = unknown +hostinfo = unknown +/bin/machine = unknown +/usr/bin/oslevel = unknown +/bin/universe = unknown + +PATH: /storage/appl/n1ge6u7/bin/lx24-amd64 +PATH: /opt/sun/n1gc/bin +PATH: /usr/local/bin +PATH: /bin +PATH: /usr/bin +PATH: /opt/c3-4/ +PATH: /usr/X11R6/bin +PATH: /usr/local/bin +PATH: /usr/local/bin/X11R5 +PATH: /usr/local/X11R5/bin +PATH: /usr/X11R6/bin +PATH: /home/rabani/Develop/perl/GeneXPress +PATH: /home/rabani/Develop/perl/Genome +PATH: /home/rabani/Develop/perl/Lib +PATH: /home/rabani/Develop/perl/Parsers +PATH: /home/rabani/Develop/perl/RNA +PATH: /home/rabani/Develop/perl/Sequence +PATH: /home/rabani/Develop/perl/System +PATH: /home/rabani/Develop/perl/Web +PATH: /home/rabani/Develop/perl/Web/DataDir +PATH: /home/rabani/Develop/genie_release64/Programs +PATH: /storage/appl/matlab14.3/bin +PATH: /home/rabani + + +## ----------- ## +## Core tests. ## +## ----------- ## + +configure:1364: checking for a BSD-compatible install +configure:1419: result: /usr/bin/install -c +configure:1430: checking whether build environment is sane +configure:1473: result: yes +configure:1538: checking for gawk +configure:1554: found /bin/gawk +configure:1564: result: gawk +configure:1574: checking whether make sets $(MAKE) +configure:1594: result: yes +configure:1763: checking if malloc debugging is wanted +configure:1784: result: no +configure:1835: checking for gcc +configure:1851: found /usr/bin/gcc +configure:1861: result: gcc +configure:2105: checking for C compiler version +configure:2108: gcc --version &5 +gcc (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:2111: $? = 0 +configure:2113: gcc -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:2116: $? = 0 +configure:2118: gcc -V &5 +gcc: `-V' option must have argument +configure:2121: $? = 1 +configure:2144: checking for C compiler default output file name +configure:2147: gcc conftest.c >&5 +configure:2150: $? = 0 +configure:2196: result: a.out +configure:2201: checking whether the C compiler works +configure:2207: ./a.out +configure:2210: $? = 0 +configure:2227: result: yes +configure:2234: checking whether we are cross compiling +configure:2236: result: no +configure:2239: checking for suffix of executables +configure:2241: gcc -o conftest conftest.c >&5 +configure:2244: $? = 0 +configure:2269: result: +configure:2275: checking for suffix of object files +configure:2296: gcc -c conftest.c >&5 +configure:2299: $? = 0 +configure:2321: result: o +configure:2325: checking whether we are using the GNU C compiler +configure:2349: gcc -c conftest.c >&5 +configure:2355: $? = 0 +configure:2359: test -z + || test ! -s conftest.err +configure:2362: $? = 0 +configure:2365: test -s conftest.o +configure:2368: $? = 0 +configure:2381: result: yes +configure:2387: checking whether gcc accepts -g +configure:2408: gcc -c -g conftest.c >&5 +configure:2414: $? = 0 +configure:2418: test -z + || test ! -s conftest.err +configure:2421: $? = 0 +configure:2424: test -s conftest.o +configure:2427: $? = 0 +configure:2438: result: yes +configure:2455: checking for gcc option to accept ANSI C +configure:2525: gcc -c -g -O2 conftest.c >&5 +configure:2531: $? = 0 +configure:2535: test -z + || test ! -s conftest.err +configure:2538: $? = 0 +configure:2541: test -s conftest.o +configure:2544: $? = 0 +configure:2562: result: none needed +configure:2580: gcc -c -g -O2 conftest.c >&5 +conftest.c:2: error: syntax error before "me" +configure:2586: $? = 1 +configure: failed program was: +| #ifndef __cplusplus +| choke me +| #endif +configure:2730: checking for style of include used by make +configure:2758: result: GNU +configure:2786: checking dependency style of gcc +configure:2876: result: gcc3 +configure:2893: checking whether make sets $(MAKE) +configure:2913: result: yes +configure:2937: checking build system type +configure:2955: result: x86_64-unknown-linux-gnu +configure:2963: checking host system type +configure:2977: result: x86_64-unknown-linux-gnu +configure:3000: checking for ViennaRNA package +configure:3043: result: headers in "../H" and library... "../lib" +configure:3050: checking for exp in -lm +configure:3080: gcc -o conftest -g -O2 -I../H -L../lib conftest.c -lm >&5 +conftest.c:18: warning: conflicting types for built-in function 'exp' +configure:3086: $? = 0 +configure:3090: test -z + || test ! -s conftest.err +configure:3093: $? = 0 +configure:3096: test -s conftest +configure:3099: $? = 0 +configure:3112: result: yes +configure:3132: checking how to run the C preprocessor +configure:3167: gcc -E -I../H conftest.c +configure:3173: $? = 0 +configure:3205: gcc -E -I../H conftest.c +conftest.c:12:28: ac_nonexistent.h: No such file or directory +configure:3211: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "Kinfold" +| #define PACKAGE_TARNAME "kinfold" +| #define PACKAGE_VERSION "1.0" +| #define PACKAGE_STRING "Kinfold 1.0" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "kinfold" +| #define VERSION "1.0" +| #define HAVE_LIBM 1 +| /* end confdefs.h. */ +| #include +configure:3250: result: gcc -E +configure:3274: gcc -E -I../H conftest.c +configure:3280: $? = 0 +configure:3312: gcc -E -I../H conftest.c +conftest.c:12:28: ac_nonexistent.h: No such file or directory +configure:3318: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "Kinfold" +| #define PACKAGE_TARNAME "kinfold" +| #define PACKAGE_VERSION "1.0" +| #define PACKAGE_STRING "Kinfold 1.0" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "kinfold" +| #define VERSION "1.0" +| #define HAVE_LIBM 1 +| /* end confdefs.h. */ +| #include +configure:3362: checking for egrep +configure:3372: result: grep -E +configure:3377: checking for ANSI C header files +configure:3402: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3408: $? = 0 +configure:3412: test -z + || test ! -s conftest.err +configure:3415: $? = 0 +configure:3418: test -s conftest.o +configure:3421: $? = 0 +configure:3510: gcc -o conftest -g -O2 -I../H -L../lib conftest.c -lRNA -lm >&5 +/usr/bin/ld: skipping incompatible ../lib/libRNA.a when searching for -lRNA +/usr/bin/ld: cannot find -lRNA +collect2: ld returned 1 exit status +configure:3513: $? = 1 +configure: program exited with status 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "Kinfold" +| #define PACKAGE_TARNAME "kinfold" +| #define PACKAGE_VERSION "1.0" +| #define PACKAGE_STRING "Kinfold 1.0" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "kinfold" +| #define VERSION "1.0" +| #define HAVE_LIBM 1 +| /* end confdefs.h. */ +| #include +| #if ((' ' & 0x0FF) == 0x020) +| # define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +| # define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +| #else +| # define ISLOWER(c) (('a' <= (c) && (c) <= 'i') || ('j' <= (c) && (c) <= 'r') || ('s' <= (c) && (c) <= 'z')) +| # define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +| #endif +| +| #define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +| int +| main () +| { +| int i; +| for (i = 0; i < 256; i++) +| if (XOR (islower (i), ISLOWER (i)) +| || toupper (i) != TOUPPER (i)) +| exit(2); +| exit (0); +| } +configure:3533: result: no +configure:3557: checking for sys/types.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for sys/stat.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for stdlib.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for string.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for memory.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for strings.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for inttypes.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for stdint.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3557: checking for unistd.h +configure:3573: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3579: $? = 0 +configure:3583: test -z + || test ! -s conftest.err +configure:3586: $? = 0 +configure:3589: test -s conftest.o +configure:3592: $? = 0 +configure:3603: result: yes +configure:3632: checking limits.h usability +configure:3644: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3650: $? = 0 +configure:3654: test -z + || test ! -s conftest.err +configure:3657: $? = 0 +configure:3660: test -s conftest.o +configure:3663: $? = 0 +configure:3673: result: yes +configure:3677: checking limits.h presence +configure:3687: gcc -E -I../H conftest.c +configure:3693: $? = 0 +configure:3713: result: yes +configure:3748: checking for limits.h +configure:3755: result: yes +configure:3632: checking sys/time.h usability +configure:3644: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3650: $? = 0 +configure:3654: test -z + || test ! -s conftest.err +configure:3657: $? = 0 +configure:3660: test -s conftest.o +configure:3663: $? = 0 +configure:3673: result: yes +configure:3677: checking sys/time.h presence +configure:3687: gcc -E -I../H conftest.c +configure:3693: $? = 0 +configure:3713: result: yes +configure:3748: checking for sys/time.h +configure:3755: result: yes +configure:3623: checking for unistd.h +configure:3628: result: yes +configure:3632: checking fold.h usability +configure:3644: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3650: $? = 0 +configure:3654: test -z + || test ! -s conftest.err +configure:3657: $? = 0 +configure:3660: test -s conftest.o +configure:3663: $? = 0 +configure:3673: result: yes +configure:3677: checking fold.h presence +configure:3687: gcc -E -I../H conftest.c +configure:3693: $? = 0 +configure:3713: result: yes +configure:3748: checking for fold.h +configure:3755: result: yes +configure:3769: checking for an ANSI C-conforming const +configure:3836: gcc -c -g -O2 -I../H conftest.c >&5 +configure:3842: $? = 0 +configure:3846: test -z + || test ! -s conftest.err +configure:3849: $? = 0 +configure:3852: test -s conftest.o +configure:3855: $? = 0 +configure:3866: result: yes +configure:3881: checking for strdup +configure:3938: gcc -o conftest -g -O2 -I../H -L../lib conftest.c -lRNA -lm >&5 +conftest.c:49: warning: conflicting types for built-in function 'strdup' +/usr/bin/ld: skipping incompatible ../lib/libRNA.a when searching for -lRNA +/usr/bin/ld: cannot find -lRNA +collect2: ld returned 1 exit status +configure:3944: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "Kinfold" +| #define PACKAGE_TARNAME "kinfold" +| #define PACKAGE_VERSION "1.0" +| #define PACKAGE_STRING "Kinfold 1.0" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "kinfold" +| #define VERSION "1.0" +| #define HAVE_LIBM 1 +| #define HAVE_SYS_TYPES_H 1 +| #define HAVE_SYS_STAT_H 1 +| #define HAVE_STDLIB_H 1 +| #define HAVE_STRING_H 1 +| #define HAVE_MEMORY_H 1 +| #define HAVE_STRINGS_H 1 +| #define HAVE_INTTYPES_H 1 +| #define HAVE_STDINT_H 1 +| #define HAVE_UNISTD_H 1 +| #define HAVE_LIMITS_H 1 +| #define HAVE_SYS_TIME_H 1 +| #define HAVE_UNISTD_H 1 +| #define HAVE_FOLD_H 1 +| /* end confdefs.h. */ +| /* Define strdup to an innocuous variant, in case declares strdup. +| For example, HP-UX 11i declares gettimeofday. */ +| #define strdup innocuous_strdup +| +| /* System header to define __stub macros and hopefully few prototypes, +| which can conflict with char strdup (); below. +| Prefer to if __STDC__ is defined, since +| exists even on freestanding compilers. */ +| +| #ifdef __STDC__ +| # include +| #else +| # include +| #endif +| +| #undef strdup +| +| /* Override any gcc2 internal prototype to avoid an error. */ +| #ifdef __cplusplus +| extern "C" +| { +| #endif +| /* We use char because int might match the return type of a gcc2 +| builtin and then its argument prototype would still apply. */ +| char strdup (); +| /* The GNU C library defines this for functions which it implements +| to always fail with ENOSYS. Some functions are actually named +| something starting with __ and the normal name is an alias. */ +| #if defined (__stub_strdup) || defined (__stub___strdup) +| choke me +| #else +| char (*f) () = strdup; +| #endif +| #ifdef __cplusplus +| } +| #endif +| +| int +| main () +| { +| return f != strdup; +| ; +| return 0; +| } +configure:3969: result: no +configure:4090: creating ./config.status + +## ---------------------- ## +## Running config.status. ## +## ---------------------- ## + +This file was extended by Kinfold config.status 1.0, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = + CONFIG_HEADERS = + CONFIG_LINKS = + CONFIG_COMMANDS = + $ ./config.status + +on mcluster02 + +config.status:699: creating Makefile +config.status:699: creating Example/Makefile +config.status:803: creating config.h +config.status:917: config.h is unchanged +config.status:1097: executing depfiles commands + +## ---------------- ## +## Cache variables. ## +## ---------------- ## + +ac_cv_build=x86_64-unknown-linux-gnu +ac_cv_build_alias=x86_64-unknown-linux-gnu +ac_cv_c_compiler_gnu=yes +ac_cv_c_const=yes +ac_cv_env_CC_set= +ac_cv_env_CC_value= +ac_cv_env_CFLAGS_set= +ac_cv_env_CFLAGS_value= +ac_cv_env_CPPFLAGS_set= +ac_cv_env_CPPFLAGS_value= +ac_cv_env_CPP_set= +ac_cv_env_CPP_value= +ac_cv_env_LDFLAGS_set= +ac_cv_env_LDFLAGS_value= +ac_cv_env_build_alias_set= +ac_cv_env_build_alias_value= +ac_cv_env_host_alias_set= +ac_cv_env_host_alias_value= +ac_cv_env_target_alias_set= +ac_cv_env_target_alias_value= +ac_cv_exeext= +ac_cv_func_strdup=no +ac_cv_header_fold_h=yes +ac_cv_header_inttypes_h=yes +ac_cv_header_limits_h=yes +ac_cv_header_memory_h=yes +ac_cv_header_stdc=no +ac_cv_header_stdint_h=yes +ac_cv_header_stdlib_h=yes +ac_cv_header_string_h=yes +ac_cv_header_strings_h=yes +ac_cv_header_sys_stat_h=yes +ac_cv_header_sys_time_h=yes +ac_cv_header_sys_types_h=yes +ac_cv_header_unistd_h=yes +ac_cv_host=x86_64-unknown-linux-gnu +ac_cv_host_alias=x86_64-unknown-linux-gnu +ac_cv_lib_m_exp=yes +ac_cv_objext=o +ac_cv_path_install='/usr/bin/install -c' +ac_cv_prog_AWK=gawk +ac_cv_prog_CPP='gcc -E' +ac_cv_prog_ac_ct_CC=gcc +ac_cv_prog_cc_g=yes +ac_cv_prog_cc_stdc= +ac_cv_prog_egrep='grep -E' +ac_cv_prog_make_make_set=yes +am_cv_CC_dependencies_compiler_type=gcc3 + +## ----------------- ## +## Output variables. ## +## ----------------- ## + +ACLOCAL='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run aclocal-1.9' +AMDEPBACKSLASH='\' +AMDEP_FALSE='#' +AMDEP_TRUE='' +AMTAR='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run tar' +AUTOCONF='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoconf' +AUTOHEADER='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoheader' +AUTOMAKE='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run automake-1.9' +AWK='gawk' +CC='gcc' +CCDEPMODE='depmode=gcc3' +CFLAGS='-g -O2' +CPP='gcc -E' +CPPFLAGS=' -I../H' +CYGPATH_W='echo' +DEFS='-DHAVE_CONFIG_H' +DEPDIR='.deps' +ECHO_C='' +ECHO_N='-n' +ECHO_T='' +EGREP='grep -E' +EXEEXT='' +INSTALL_DATA='${INSTALL} -m 644' +INSTALL_PROGRAM='${INSTALL}' +INSTALL_SCRIPT='${INSTALL}' +INSTALL_STRIP_PROGRAM='${SHELL} $(install_sh) -c -s' +ISODATE='2006-06-13' +LDFLAGS='-L../lib ' +LIBOBJS='' +LIBS='-lRNA -lm ' +LTLIBOBJS='' +MAKEINFO='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run makeinfo' +OBJEXT='o' +PACKAGE='kinfold' +PACKAGE_BUGREPORT='rna@tbi.univie.ac.at' +PACKAGE_NAME='Kinfold' +PACKAGE_STRING='Kinfold 1.0' +PACKAGE_TARNAME='kinfold' +PACKAGE_VERSION='1.0' +PATH_SEPARATOR=':' +SET_MAKE='' +SHELL='/bin/sh' +STRIP='' +VERSION='1.0' +ac_ct_CC='gcc' +ac_ct_STRIP='' +am__fastdepCC_FALSE='#' +am__fastdepCC_TRUE='' +am__include='include' +am__leading_dot='.' +am__quote='' +am__tar='${AMTAR} chof - "$$tardir"' +am__untar='${AMTAR} xf -' +bindir='${exec_prefix}/bin' +build='x86_64-unknown-linux-gnu' +build_alias='' +build_cpu='x86_64' +build_os='linux-gnu' +build_vendor='unknown' +datadir='${prefix}/share' +exec_prefix='${prefix}' +host='x86_64-unknown-linux-gnu' +host_alias='' +host_cpu='x86_64' +host_os='linux-gnu' +host_vendor='unknown' +includedir='${prefix}/include' +infodir='${prefix}/info' +install_sh='/home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/install-sh' +libdir='${exec_prefix}/lib' +libexecdir='${exec_prefix}/libexec' +localstatedir='${prefix}/var' +mandir='${prefix}/man' +mkdir_p='mkdir -p --' +oldincludedir='/usr/include' +prefix='/usr/local' +program_transform_name='s,x,x,' +sbindir='${exec_prefix}/sbin' +sharedstatedir='${prefix}/com' +sysconfdir='${prefix}/etc' +target_alias='' + +## ----------- ## +## confdefs.h. ## +## ----------- ## + +#define HAVE_FOLD_H 1 +#define HAVE_INTTYPES_H 1 +#define HAVE_LIBM 1 +#define HAVE_LIMITS_H 1 +#define HAVE_MEMORY_H 1 +#define HAVE_STDINT_H 1 +#define HAVE_STDLIB_H 1 +#define HAVE_STRINGS_H 1 +#define HAVE_STRING_H 1 +#define HAVE_SYS_STAT_H 1 +#define HAVE_SYS_TIME_H 1 +#define HAVE_SYS_TYPES_H 1 +#define HAVE_UNISTD_H 1 +#define HAVE_UNISTD_H 1 +#define PACKAGE "kinfold" +#define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +#define PACKAGE_NAME "Kinfold" +#define PACKAGE_STRING "Kinfold 1.0" +#define PACKAGE_TARNAME "kinfold" +#define PACKAGE_VERSION "1.0" +#define VERSION "1.0" + +configure: exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.status b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.status new file mode 100755 index 00000000..4be07f4d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/config.status @@ -0,0 +1,1188 @@ +#! /bin/sh +# Generated by configure. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=${CONFIG_SHELL-/bin/sh} +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-) + sed '=' <$as_myself | + sed ' + N + s,$,-, + : loop + s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3, + t loop + s,-$,, + s,^['$as_cr_digits']*\n,, + ' >$as_me.lineno && + chmod +x $as_me.lineno || + { { echo "$as_me:$LINENO: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&5 +echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2;} + { (exit 1); exit 1; }; } + + # Don't try to exec as it changes $[0], causing all sort of problems + # (the dirname of $[0] is not the place where we might find the + # original and so on. Autoconf is especially sensible to this). + . ./$as_me.lineno + # Exit status is that of the last command. + exit +} + + +case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in + *c*,-n*) ECHO_N= ECHO_C=' +' ECHO_T=' ' ;; + *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;; + *) ECHO_N= ECHO_C='\c' ECHO_T= ;; +esac + +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +rm -f conf$$ conf$$.exe conf$$.file +echo >conf$$.file +if ln -s conf$$.file conf$$ 2>/dev/null; then + # We could just check for DJGPP; but this test a) works b) is more generic + # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04). + if test -f conf$$.exe; then + # Don't use ln at all; we don't have any links + as_ln_s='cp -p' + else + as_ln_s='ln -s' + fi +elif ln conf$$.file conf$$ 2>/dev/null; then + as_ln_s=ln +else + as_ln_s='cp -p' +fi +rm -f conf$$ conf$$.exe conf$$.file + +if mkdir -p . 2>/dev/null; then + as_mkdir_p=: +else + test -d ./-p && rmdir ./-p + as_mkdir_p=false +fi + +as_executable_p="test -f" + +# Sed expression to map a string onto a valid CPP name. +as_tr_cpp="eval sed 'y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g'" + +# Sed expression to map a string onto a valid variable name. +as_tr_sh="eval sed 'y%*+%pp%;s%[^_$as_cr_alnum]%_%g'" + + +# IFS +# We need space, tab and new line, in precisely that order. +as_nl=' +' +IFS=" $as_nl" + +# CDPATH. +$as_unset CDPATH + +exec 6>&1 + +# Open the log real soon, to keep \$[0] and so on meaningful, and to +# report actual input values of CONFIG_FILES etc. instead of their +# values after options handling. 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Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +config_files=" Makefile Example/Makefile" +config_headers=" config.h" +config_commands=" depfiles" + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +ac_cs_version="\ +Kinfold config.status 1.0 +configured by ./configure, generated by GNU Autoconf 2.59, + with options \"'--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.'\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=. +INSTALL="/usr/bin/install -c" +# If no file are specified by the user, then we need to provide default +# value. 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Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. 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See below for descriptions of some of the useful variables. + +Defaults for the options are specified in brackets. + +Configuration: + -h, --help display this help and exit + --help=short display options specific to this package + --help=recursive display the short help of all the included packages + -V, --version display version information and exit + -q, --quiet, --silent do not print \`checking...' messages + --cache-file=FILE cache test results in FILE [disabled] + -C, --config-cache alias for \`--cache-file=config.cache' + -n, --no-create do not create output files + --srcdir=DIR find the sources in DIR [configure dir or \`..'] + +_ACEOF + + cat <<_ACEOF +Installation directories: + --prefix=PREFIX install architecture-independent files in PREFIX + [$ac_default_prefix] + --exec-prefix=EPREFIX install architecture-dependent files in EPREFIX + [PREFIX] + +By default, \`make install' will install all the files in +\`$ac_default_prefix/bin', \`$ac_default_prefix/lib' etc. You can specify +an installation prefix other than \`$ac_default_prefix' using \`--prefix', +for instance \`--prefix=\$HOME'. + +For better control, use the options below. + +Fine tuning of the installation directories: + --bindir=DIR user executables [EPREFIX/bin] + --sbindir=DIR system admin executables [EPREFIX/sbin] + --libexecdir=DIR program executables [EPREFIX/libexec] + --datadir=DIR read-only architecture-independent data [PREFIX/share] + --sysconfdir=DIR read-only single-machine data [PREFIX/etc] + --sharedstatedir=DIR modifiable architecture-independent data [PREFIX/com] + --localstatedir=DIR modifiable single-machine data [PREFIX/var] + --libdir=DIR object code libraries [EPREFIX/lib] + --includedir=DIR C header files [PREFIX/include] + --oldincludedir=DIR C header files for non-gcc [/usr/include] + --infodir=DIR info documentation [PREFIX/info] + --mandir=DIR man documentation [PREFIX/man] +_ACEOF + + cat <<\_ACEOF + +Program names: + --program-prefix=PREFIX prepend PREFIX to installed program names + --program-suffix=SUFFIX append SUFFIX to installed program names + --program-transform-name=PROGRAM run sed PROGRAM on installed program names + +System types: + --build=BUILD configure for building on BUILD [guessed] + --host=HOST cross-compile to build programs to run on HOST [BUILD] +_ACEOF +fi + +if test -n "$ac_init_help"; then + case $ac_init_help in + short | recursive ) echo "Configuration of Kinfold 1.0:";; + esac + cat <<\_ACEOF + +Optional Features: + --disable-FEATURE do not include FEATURE (same as --enable-FEATURE=no) + --enable-FEATURE[=ARG] include FEATURE [ARG=yes] + --disable-dependency-tracking speeds up one-time build + --enable-dependency-tracking do not reject slow dependency extractors + +Optional Packages: + --with-PACKAGE[=ARG] use PACKAGE [ARG=yes] + --without-PACKAGE do not use PACKAGE (same as --with-PACKAGE=no) + --with-dmalloc use dmalloc, as in + http://www.dmalloc.com/dmalloc.tar.gz + --with-ViennaRNA-include where to search for ViennaRNA header files + --with-ViennaRNA-lib where to search for libRNA.a + +Some influential environment variables: + CC C compiler command + CFLAGS C compiler flags + LDFLAGS linker flags, e.g. -L if you have libraries in a + nonstandard directory + CPPFLAGS C/C++ preprocessor flags, e.g. -I if you have + headers in a nonstandard directory + CPP C preprocessor + +Use these variables to override the choices made by `configure' or to help +it to find libraries and programs with nonstandard names/locations. + +Report bugs to . +_ACEOF +fi + +if test "$ac_init_help" = "recursive"; then + # If there are subdirs, report their specific --help. + ac_popdir=`pwd` + for ac_dir in : $ac_subdirs_all; do test "x$ac_dir" = x: && continue + test -d $ac_dir || continue + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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Use of quotes ensures accuracy. + *) ac_configure_args="$ac_configure_args '$ac_arg'" ;; + esac + fi +done +if $ac_cache_corrupted; then + { echo "$as_me:$LINENO: error: changes in the environment can compromise the build" >&5 +echo "$as_me: error: changes in the environment can compromise the build" >&2;} + { { echo "$as_me:$LINENO: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&5 +echo "$as_me: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + + + + + + + + + + + + + + + + + + + + + + + + + + + + +am__api_version="1.9" +ac_aux_dir= +for ac_dir in $srcdir $srcdir/.. $srcdir/../..; do + if test -f $ac_dir/install-sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install-sh -c" + break + elif test -f $ac_dir/install.sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install.sh -c" + break + elif test -f $ac_dir/shtool; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/shtool install -c" + break + fi +done +if test -z "$ac_aux_dir"; then + { { echo "$as_me:$LINENO: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&5 +echo "$as_me: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&2;} + { (exit 1); exit 1; }; } +fi +ac_config_guess="$SHELL $ac_aux_dir/config.guess" +ac_config_sub="$SHELL $ac_aux_dir/config.sub" +ac_configure="$SHELL $ac_aux_dir/configure" # This should be Cygnus configure. + +# Find a good install program. We prefer a C program (faster), +# so one script is as good as another. But avoid the broken or +# incompatible versions: +# SysV /etc/install, /usr/sbin/install +# SunOS /usr/etc/install +# IRIX /sbin/install +# AIX /bin/install +# AmigaOS /C/install, which installs bootblocks on floppy discs +# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag +# AFS /usr/afsws/bin/install, which mishandles nonexistent args +# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff" +# OS/2's system install, which has a completely different semantic +# ./install, which can be erroneously created by make from ./install.sh. +echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5 +echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6 +if test -z "$INSTALL"; then +if test "${ac_cv_path_install+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + # Account for people who put trailing slashes in PATH elements. +case $as_dir/ in + ./ | .// | /cC/* | \ + /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \ + ?:\\/os2\\/install\\/* | ?:\\/OS2\\/INSTALL\\/* | \ + /usr/ucb/* ) ;; + *) + # OSF1 and SCO ODT 3.0 have their own names for install. + # Don't use installbsd from OSF since it installs stuff as root + # by default. + for ac_prog in ginstall scoinst install; do + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then + if test $ac_prog = install && + grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # AIX install. It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +echo "$as_me:$LINENO: checking whether build environment is sane" >&5 +echo $ECHO_N "checking whether build environment is sane... $ECHO_C" >&6 +# Just in case +sleep 1 +echo timestamp > conftest.file +# Do `set' in a subshell so we don't clobber the current shell's +# arguments. Must try -L first in case configure is actually a +# symlink; some systems play weird games with the mod time of symlinks +# (eg FreeBSD returns the mod time of the symlink's containing +# directory). +if ( + set X `ls -Lt $srcdir/configure conftest.file 2> /dev/null` + if test "$*" = "X"; then + # -L didn't work. + set X `ls -t $srcdir/configure conftest.file` + fi + rm -f conftest.file + if test "$*" != "X $srcdir/configure conftest.file" \ + && test "$*" != "X conftest.file $srcdir/configure"; then + + # If neither matched, then we have a broken ls. This can happen + # if, for instance, CONFIG_SHELL is bash and it inherits a + # broken ls alias from the environment. This has actually + # happened. Such a system could not be considered "sane". + { { echo "$as_me:$LINENO: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&5 +echo "$as_me: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&2;} + { (exit 1); exit 1; }; } + fi + + test "$2" = conftest.file + ) +then + # Ok. + : +else + { { echo "$as_me:$LINENO: error: newly created file is older than distributed files! +Check your system clock" >&5 +echo "$as_me: error: newly created file is older than distributed files! +Check your system clock" >&2;} + { (exit 1); exit 1; }; } +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 +test "$program_prefix" != NONE && + program_transform_name="s,^,$program_prefix,;$program_transform_name" +# Use a double $ so make ignores it. +test "$program_suffix" != NONE && + program_transform_name="s,\$,$program_suffix,;$program_transform_name" +# Double any \ or $. echo might interpret backslashes. +# By default was `s,x,x', remove it if useless. +cat <<\_ACEOF >conftest.sed +s/[\\$]/&&/g;s/;s,x,x,$// +_ACEOF +program_transform_name=`echo $program_transform_name | sed -f conftest.sed` +rm conftest.sed + +# expand $ac_aux_dir to an absolute path +am_aux_dir=`cd $ac_aux_dir && pwd` + +test x"${MISSING+set}" = xset || MISSING="\${SHELL} $am_aux_dir/missing" +# Use eval to expand $SHELL +if eval "$MISSING --run true"; then + am_missing_run="$MISSING --run " +else + am_missing_run= + { echo "$as_me:$LINENO: WARNING: \`missing' script is too old or missing" >&5 +echo "$as_me: WARNING: \`missing' script is too old or missing" >&2;} +fi + +if mkdir -p --version . >/dev/null 2>&1 && test ! -d ./--version; then + # We used to keeping the `.' as first argument, in order to + # allow $(mkdir_p) to be used without argument. As in + # $(mkdir_p) $(somedir) + # where $(somedir) is conditionally defined. However this is wrong + # for two reasons: + # 1. if the package is installed by a user who cannot write `.' + # make install will fail, + # 2. the above comment should most certainly read + # $(mkdir_p) $(DESTDIR)$(somedir) + # so it does not work when $(somedir) is undefined and + # $(DESTDIR) is not. + # To support the latter case, we have to write + # test -z "$(somedir)" || $(mkdir_p) $(DESTDIR)$(somedir), + # so the `.' trick is pointless. + mkdir_p='mkdir -p --' +else + # On NextStep and OpenStep, the `mkdir' command does not + # recognize any option. It will interpret all options as + # directories to create, and then abort because `.' already + # exists. + for d in ./-p ./--version; + do + test -d $d && rmdir $d + done + # $(mkinstalldirs) is defined by Automake if mkinstalldirs exists. + if test -f "$ac_aux_dir/mkinstalldirs"; then + mkdir_p='$(mkinstalldirs)' + else + mkdir_p='$(install_sh) -d' + fi +fi + +for ac_prog in gawk mawk nawk awk +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_AWK+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$AWK"; then + ac_cv_prog_AWK="$AWK" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_AWK="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +AWK=$ac_cv_prog_AWK +if test -n "$AWK"; then + echo "$as_me:$LINENO: result: $AWK" >&5 +echo "${ECHO_T}$AWK" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$AWK" && break +done + +echo "$as_me:$LINENO: checking whether ${MAKE-make} sets \$(MAKE)" >&5 +echo $ECHO_N "checking whether ${MAKE-make} sets \$(MAKE)... $ECHO_C" >&6 +set dummy ${MAKE-make}; ac_make=`echo "$2" | sed 'y,:./+-,___p_,'` +if eval "test \"\${ac_cv_prog_make_${ac_make}_set+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.make <<\_ACEOF +all: + @echo 'ac_maketemp="$(MAKE)"' +_ACEOF +# GNU make sometimes prints "make[1]: Entering...", which would confuse us. +eval `${MAKE-make} -f conftest.make 2>/dev/null | grep temp=` +if test -n "$ac_maketemp"; then + eval ac_cv_prog_make_${ac_make}_set=yes +else + eval ac_cv_prog_make_${ac_make}_set=no +fi +rm -f conftest.make +fi +if eval "test \"`echo '$ac_cv_prog_make_'${ac_make}_set`\" = yes"; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + SET_MAKE= +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + SET_MAKE="MAKE=${MAKE-make}" +fi + +rm -rf .tst 2>/dev/null +mkdir .tst 2>/dev/null +if test -d .tst; then + am__leading_dot=. +else + am__leading_dot=_ +fi +rmdir .tst 2>/dev/null + +# test to see if srcdir already configured +if test "`cd $srcdir && pwd`" != "`pwd`" && + test -f $srcdir/config.status; then + { { echo "$as_me:$LINENO: error: source directory already configured; run \"make distclean\" there first" >&5 +echo "$as_me: error: source directory already configured; run \"make distclean\" there first" >&2;} + { (exit 1); exit 1; }; } +fi + +# test whether we have cygpath +if test -z "$CYGPATH_W"; then + if (cygpath --version) >/dev/null 2>/dev/null; then + CYGPATH_W='cygpath -w' + else + CYGPATH_W=echo + fi +fi + + +# Define the identity of the package. + PACKAGE='kinfold' + VERSION='1.0' + + +cat >>confdefs.h <<_ACEOF +#define PACKAGE "$PACKAGE" +_ACEOF + + +cat >>confdefs.h <<_ACEOF +#define VERSION "$VERSION" +_ACEOF + +# Some tools Automake needs. + +ACLOCAL=${ACLOCAL-"${am_missing_run}aclocal-${am__api_version}"} + + +AUTOCONF=${AUTOCONF-"${am_missing_run}autoconf"} + + +AUTOMAKE=${AUTOMAKE-"${am_missing_run}automake-${am__api_version}"} + + +AUTOHEADER=${AUTOHEADER-"${am_missing_run}autoheader"} + + +MAKEINFO=${MAKEINFO-"${am_missing_run}makeinfo"} + +install_sh=${install_sh-"$am_aux_dir/install-sh"} + +# Installed binaries are usually stripped using `strip' when the user +# run `make install-strip'. However `strip' might not be the right +# tool to use in cross-compilation environments, therefore Automake +# will honor the `STRIP' environment variable to overrule this program. +if test "$cross_compiling" != no; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}strip", so it can be a program name with args. +set dummy ${ac_tool_prefix}strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$STRIP"; then + ac_cv_prog_STRIP="$STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_STRIP="${ac_tool_prefix}strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +STRIP=$ac_cv_prog_STRIP +if test -n "$STRIP"; then + echo "$as_me:$LINENO: result: $STRIP" >&5 +echo "${ECHO_T}$STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_STRIP"; then + ac_ct_STRIP=$STRIP + # Extract the first word of "strip", so it can be a program name with args. +set dummy strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_STRIP"; then + ac_cv_prog_ac_ct_STRIP="$ac_ct_STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_STRIP="strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_STRIP" && ac_cv_prog_ac_ct_STRIP=":" +fi +fi +ac_ct_STRIP=$ac_cv_prog_ac_ct_STRIP +if test -n "$ac_ct_STRIP"; then + echo "$as_me:$LINENO: result: $ac_ct_STRIP" >&5 +echo "${ECHO_T}$ac_ct_STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + STRIP=$ac_ct_STRIP +else + STRIP="$ac_cv_prog_STRIP" +fi + +fi +INSTALL_STRIP_PROGRAM="\${SHELL} \$(install_sh) -c -s" + +# We need awk for the "check" target. The system "awk" is bad on +# some platforms. +# Always define AMTAR for backward compatibility. + +AMTAR=${AMTAR-"${am_missing_run}tar"} + +am__tar='${AMTAR} chof - "$$tardir"'; am__untar='${AMTAR} xf -' + + + + + + +echo "$as_me:$LINENO: checking if malloc debugging is wanted" >&5 +echo $ECHO_N "checking if malloc debugging is wanted... $ECHO_C" >&6 + +# Check whether --with-dmalloc or --without-dmalloc was given. +if test "${with_dmalloc+set}" = set; then + withval="$with_dmalloc" + if test "$withval" = yes; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +cat >>confdefs.h <<\_ACEOF +#define WITH_DMALLOC 1 +_ACEOF + + LIBS="$LIBS -ldmalloc" + LDFLAGS="$LDFLAGS -g" +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi; + + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args. +set dummy ${ac_tool_prefix}gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "gcc", so it can be a program name with args. +set dummy gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args. +set dummy ${ac_tool_prefix}cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +fi +if test -z "$CC"; then + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else + ac_prog_rejected=no +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then + ac_prog_rejected=yes + continue + fi + ac_cv_prog_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +if test $ac_prog_rejected = yes; then + # We found a bogon in the path, so make sure we never use it. + set dummy $ac_cv_prog_CC + shift + if test $# != 0; then + # We chose a different compiler from the bogus one. + # However, it has the same basename, so the bogon will be chosen + # first if we set CC to just the basename; use the full file name. + shift + ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@" + fi +fi +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + for ac_prog in cl + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CC" && break + done +fi +if test -z "$CC"; then + ac_ct_CC=$CC + for ac_prog in cl +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CC" && break +done + + CC=$ac_ct_CC +fi + +fi + + +test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&5 +echo "$as_me: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files a.out a.exe b.out" +# Try to create an executable without -o first, disregard a.out. +# It will help us diagnose broken compilers, and finding out an intuition +# of exeext. +echo "$as_me:$LINENO: checking for C compiler default output file name" >&5 +echo $ECHO_N "checking for C compiler default output file name... $ECHO_C" >&6 +ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'` +if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5 + (eval $ac_link_default) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # Find the output, starting from the most likely. This scheme is +# not robust to junk in `.', hence go to wildcards (a.*) only as a last +# resort. + +# Be careful to initialize this variable, since it used to be cached. +# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile. +ac_cv_exeext= +# b.out is created by i960 compilers. +for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out +do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) + ;; + conftest.$ac_ext ) + # This is the source file. + ;; + [ab].out ) + # We found the default executable, but exeext='' is most + # certainly right. + break;; + *.* ) + ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + # FIXME: I believe we export ac_cv_exeext for Libtool, + # but it would be cool to find out if it's true. Does anybody + # maintain Libtool? --akim. + export ac_cv_exeext + break;; + * ) + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: C compiler cannot create executables +See \`config.log' for more details." >&5 +echo "$as_me: error: C compiler cannot create executables +See \`config.log' for more details." >&2;} + { (exit 77); exit 77; }; } +fi + +ac_exeext=$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_file" >&5 +echo "${ECHO_T}$ac_file" >&6 + +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether the C compiler works" >&5 +echo $ECHO_N "checking whether the C compiler works... $ECHO_C" >&6 +# FIXME: These cross compiler hacks should be removed for Autoconf 3.0 +# If not cross compiling, check that we can run a simple program. +if test "$cross_compiling" != yes; then + if { ac_try='./$ac_file' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + cross_compiling=no + else + if test "$cross_compiling" = maybe; then + cross_compiling=yes + else + { { echo "$as_me:$LINENO: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + fi + fi +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +rm -f a.out a.exe conftest$ac_cv_exeext b.out +ac_clean_files=$ac_clean_files_save +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether we are cross compiling" >&5 +echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6 +echo "$as_me:$LINENO: result: $cross_compiling" >&5 +echo "${ECHO_T}$cross_compiling" >&6 + +echo "$as_me:$LINENO: checking for suffix of executables" >&5 +echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6 +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # If both `conftest.exe' and `conftest' are `present' (well, observable) +# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will +# work properly (i.e., refer to `conftest.exe'), while it won't with +# `rm'. +for ac_file in conftest.exe conftest conftest.*; do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;; + *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + export ac_cv_exeext + break;; + * ) break;; + esac +done +else + { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5 +echo "${ECHO_T}$ac_cv_exeext" >&6 + +rm -f conftest.$ac_ext +EXEEXT=$ac_cv_exeext +ac_exeext=$EXEEXT +echo "$as_me:$LINENO: checking for suffix of object files" >&5 +echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6 +if test "${ac_cv_objext+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.o conftest.obj +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;; + *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'` + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest.$ac_cv_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_objext" >&5 +echo "${ECHO_T}$ac_cv_objext" >&6 +OBJEXT=$ac_cv_objext +ac_objext=$OBJEXT +echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6 +if test "${ac_cv_c_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_c_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6 +GCC=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CFLAGS=${CFLAGS+set} +ac_save_CFLAGS=$CFLAGS +CFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5 +echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cc_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_g" >&6 +if test "$ac_test_CFLAGS" = set; then + CFLAGS=$ac_save_CFLAGS +elif test $ac_cv_prog_cc_g = yes; then + if test "$GCC" = yes; then + CFLAGS="-g -O2" + else + CFLAGS="-g" + fi +else + if test "$GCC" = yes; then + CFLAGS="-O2" + else + CFLAGS= + fi +fi +echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5 +echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_prog_cc_stdc=no +ac_save_CC=$CC +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include +/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */ +struct buf { int x; }; +FILE * (*rcsopen) (struct buf *, struct stat *, int); +static char *e (p, i) + char **p; + int i; +{ + return p[i]; +} +static char *f (char * (*g) (char **, int), char **p, ...) +{ + char *s; + va_list v; + va_start (v,p); + s = g (p, va_arg (v,int)); + va_end (v); + return s; +} + +/* OSF 4.0 Compaq cc is some sort of almost-ANSI by default. It has + function prototypes and stuff, but not '\xHH' hex character constants. + These don't provoke an error unfortunately, instead are silently treated + as 'x'. The following induces an error, until -std1 is added to get + proper ANSI mode. Curiously '\x00'!='x' always comes out true, for an + array size at least. It's necessary to write '\x00'==0 to get something + that's true only with -std1. */ +int osf4_cc_array ['\x00' == 0 ? 1 : -1]; + +int test (int i, double x); +struct s1 {int (*f) (int a);}; +struct s2 {int (*f) (double a);}; +int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int); +int argc; +char **argv; +int +main () +{ +return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1]; + ; + return 0; +} +_ACEOF +# Don't try gcc -ansi; that turns off useful extensions and +# breaks some systems' header files. +# AIX -qlanglvl=ansi +# Ultrix and OSF/1 -std1 +# HP-UX 10.20 and later -Ae +# HP-UX older versions -Aa -D_HPUX_SOURCE +# SVR4 -Xc -D__EXTENSIONS__ +for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__" +do + CC="$ac_save_CC $ac_arg" + rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_stdc=$ac_arg +break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext +done +rm -f conftest.$ac_ext conftest.$ac_objext +CC=$ac_save_CC + +fi + +case "x$ac_cv_prog_cc_stdc" in + x|xno) + echo "$as_me:$LINENO: result: none needed" >&5 +echo "${ECHO_T}none needed" >&6 ;; + *) + echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6 + CC="$CC $ac_cv_prog_cc_stdc" ;; +esac + +# Some people use a C++ compiler to compile C. Since we use `exit', +# in C++ we need to declare it. In case someone uses the same compiler +# for both compiling C and C++ we need to have the C++ compiler decide +# the declaration of exit, since it's the most demanding environment. +cat >conftest.$ac_ext <<_ACEOF +#ifndef __cplusplus + choke me +#endif +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +DEPDIR="${am__leading_dot}deps" + + ac_config_commands="$ac_config_commands depfiles" + + +am_make=${MAKE-make} +cat > confinc << 'END' +am__doit: + @echo done +.PHONY: am__doit +END +# If we don't find an include directive, just comment out the code. +echo "$as_me:$LINENO: checking for style of include used by $am_make" >&5 +echo $ECHO_N "checking for style of include used by $am_make... $ECHO_C" >&6 +am__include="#" +am__quote= +_am_result=none +# First try GNU make style include. +echo "include confinc" > confmf +# We grep out `Entering directory' and `Leaving directory' +# messages which can occur if `w' ends up in MAKEFLAGS. +# In particular we don't look at `^make:' because GNU make might +# be invoked under some other name (usually "gmake"), in which +# case it prints its new name instead of `make'. +if test "`$am_make -s -f confmf 2> /dev/null | grep -v 'ing directory'`" = "done"; then + am__include=include + am__quote= + _am_result=GNU +fi +# Now try BSD make style include. +if test "$am__include" = "#"; then + echo '.include "confinc"' > confmf + if test "`$am_make -s -f confmf 2> /dev/null`" = "done"; then + am__include=.include + am__quote="\"" + _am_result=BSD + fi +fi + + +echo "$as_me:$LINENO: result: $_am_result" >&5 +echo "${ECHO_T}$_am_result" >&6 +rm -f confinc confmf + +# Check whether --enable-dependency-tracking or --disable-dependency-tracking was given. +if test "${enable_dependency_tracking+set}" = set; then + enableval="$enable_dependency_tracking" + +fi; +if test "x$enable_dependency_tracking" != xno; then + am_depcomp="$ac_aux_dir/depcomp" + AMDEPBACKSLASH='\' +fi + + +if test "x$enable_dependency_tracking" != xno; then + AMDEP_TRUE= + AMDEP_FALSE='#' +else + AMDEP_TRUE='#' + AMDEP_FALSE= +fi + + + + +depcc="$CC" am_compiler_list= + +echo "$as_me:$LINENO: checking dependency style of $depcc" >&5 +echo $ECHO_N "checking dependency style of $depcc... $ECHO_C" >&6 +if test "${am_cv_CC_dependencies_compiler_type+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then + # We make a subdir and do the tests there. Otherwise we can end up + # making bogus files that we don't know about and never remove. For + # instance it was reported that on HP-UX the gcc test will end up + # making a dummy file named `D' -- because `-MD' means `put the output + # in D'. + mkdir conftest.dir + # Copy depcomp to subdir because otherwise we won't find it if we're + # using a relative directory. + cp "$am_depcomp" conftest.dir + cd conftest.dir + # We will build objects and dependencies in a subdirectory because + # it helps to detect inapplicable dependency modes. For instance + # both Tru64's cc and ICC support -MD to output dependencies as a + # side effect of compilation, but ICC will put the dependencies in + # the current directory while Tru64 will put them in the object + # directory. + mkdir sub + + am_cv_CC_dependencies_compiler_type=none + if test "$am_compiler_list" = ""; then + am_compiler_list=`sed -n 's/^#*\([a-zA-Z0-9]*\))$/\1/p' < ./depcomp` + fi + for depmode in $am_compiler_list; do + # Setup a source with many dependencies, because some compilers + # like to wrap large dependency lists on column 80 (with \), and + # we should not choose a depcomp mode which is confused by this. + # + # We need to recreate these files for each test, as the compiler may + # overwrite some of them when testing with obscure command lines. + # This happens at least with the AIX C compiler. + : > sub/conftest.c + for i in 1 2 3 4 5 6; do + echo '#include "conftst'$i'.h"' >> sub/conftest.c + # Using `: > sub/conftst$i.h' creates only sub/conftst1.h with + # Solaris 8's {/usr,}/bin/sh. + touch sub/conftst$i.h + done + echo "${am__include} ${am__quote}sub/conftest.Po${am__quote}" > confmf + + case $depmode in + nosideeffect) + # after this tag, mechanisms are not by side-effect, so they'll + # only be used when explicitly requested + if test "x$enable_dependency_tracking" = xyes; then + continue + else + break + fi + ;; + none) break ;; + esac + # We check with `-c' and `-o' for the sake of the "dashmstdout" + # mode. It turns out that the SunPro C++ compiler does not properly + # handle `-M -o', and we need to detect this. + if depmode=$depmode \ + source=sub/conftest.c object=sub/conftest.${OBJEXT-o} \ + depfile=sub/conftest.Po tmpdepfile=sub/conftest.TPo \ + $SHELL ./depcomp $depcc -c -o sub/conftest.${OBJEXT-o} sub/conftest.c \ + >/dev/null 2>conftest.err && + grep sub/conftst6.h sub/conftest.Po > /dev/null 2>&1 && + grep sub/conftest.${OBJEXT-o} sub/conftest.Po > /dev/null 2>&1 && + ${MAKE-make} -s -f confmf > /dev/null 2>&1; then + # icc doesn't choke on unknown options, it will just issue warnings + # or remarks (even with -Werror). So we grep stderr for any message + # that says an option was ignored or not supported. + # When given -MP, icc 7.0 and 7.1 complain thusly: + # icc: Command line warning: ignoring option '-M'; no argument required + # The diagnosis changed in icc 8.0: + # icc: Command line remark: option '-MP' not supported + if (grep 'ignoring option' conftest.err || + grep 'not supported' conftest.err) >/dev/null 2>&1; then :; else + am_cv_CC_dependencies_compiler_type=$depmode + break + fi + fi + done + + cd .. + rm -rf conftest.dir +else + am_cv_CC_dependencies_compiler_type=none +fi + +fi +echo "$as_me:$LINENO: result: $am_cv_CC_dependencies_compiler_type" >&5 +echo "${ECHO_T}$am_cv_CC_dependencies_compiler_type" >&6 +CCDEPMODE=depmode=$am_cv_CC_dependencies_compiler_type + + + +if + test "x$enable_dependency_tracking" != xno \ + && test "$am_cv_CC_dependencies_compiler_type" = gcc3; then + am__fastdepCC_TRUE= + am__fastdepCC_FALSE='#' +else + am__fastdepCC_TRUE='#' + am__fastdepCC_FALSE= +fi + + +echo "$as_me:$LINENO: checking whether ${MAKE-make} sets \$(MAKE)" >&5 +echo $ECHO_N "checking whether ${MAKE-make} sets \$(MAKE)... $ECHO_C" >&6 +set dummy ${MAKE-make}; ac_make=`echo "$2" | sed 'y,:./+-,___p_,'` +if eval "test \"\${ac_cv_prog_make_${ac_make}_set+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.make <<\_ACEOF +all: + @echo 'ac_maketemp="$(MAKE)"' +_ACEOF +# GNU make sometimes prints "make[1]: Entering...", which would confuse us. +eval `${MAKE-make} -f conftest.make 2>/dev/null | grep temp=` +if test -n "$ac_maketemp"; then + eval ac_cv_prog_make_${ac_make}_set=yes +else + eval ac_cv_prog_make_${ac_make}_set=no +fi +rm -f conftest.make +fi +if eval "test \"`echo '$ac_cv_prog_make_'${ac_make}_set`\" = yes"; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + SET_MAKE= +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + SET_MAKE="MAKE=${MAKE-make}" +fi + + + ac_config_headers="$ac_config_headers config.h" + + + + +ISODATE=`date +%Y-%m-%d` + + +# Make sure we can run config.sub. +$ac_config_sub sun4 >/dev/null 2>&1 || + { { echo "$as_me:$LINENO: error: cannot run $ac_config_sub" >&5 +echo "$as_me: error: cannot run $ac_config_sub" >&2;} + { (exit 1); exit 1; }; } + +echo "$as_me:$LINENO: checking build system type" >&5 +echo $ECHO_N "checking build system type... $ECHO_C" >&6 +if test "${ac_cv_build+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_build_alias=$build_alias +test -z "$ac_cv_build_alias" && + ac_cv_build_alias=`$ac_config_guess` +test -z "$ac_cv_build_alias" && + { { echo "$as_me:$LINENO: error: cannot guess build type; you must specify one" >&5 +echo "$as_me: error: cannot guess build type; you must specify one" >&2;} + { (exit 1); exit 1; }; } +ac_cv_build=`$ac_config_sub $ac_cv_build_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_build_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_build_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_build" >&5 +echo "${ECHO_T}$ac_cv_build" >&6 +build=$ac_cv_build +build_cpu=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +build_vendor=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +build_os=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + +echo "$as_me:$LINENO: checking host system type" >&5 +echo $ECHO_N "checking host system type... $ECHO_C" >&6 +if test "${ac_cv_host+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_host_alias=$host_alias +test -z "$ac_cv_host_alias" && + ac_cv_host_alias=$ac_cv_build_alias +ac_cv_host=`$ac_config_sub $ac_cv_host_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_host_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_host_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_host" >&5 +echo "${ECHO_T}$ac_cv_host" >&6 +host=$ac_cv_host +host_cpu=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +host_vendor=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +host_os=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + + + +# Check whether --with-ViennaRNA-include or --without-ViennaRNA-include was given. +if test "${with_ViennaRNA_include+set}" = set; then + withval="$with_ViennaRNA_include" + ac_VRNA_includes="$withval" +fi; + + +# Check whether --with-ViennaRNA-lib or --without-ViennaRNA-lib was given. +if test "${with_ViennaRNA_lib+set}" = set; then + withval="$with_ViennaRNA_lib" + ac_VRNA_lib="$withval" +fi; + +echo "$as_me:$LINENO: checking for ViennaRNA package" >&5 +echo $ECHO_N "checking for ViennaRNA package... $ECHO_C" >&6 +if test -z "$ac_VRNA_includes"; then + for ac_dir in \ + ../H \ + /usr/local/include/ViennaRNA \ + /usr/local/include \ + /usr/include/ViennaRNA \ + /usr/local/ViennaRNA/H \ + /usr/local/share/ViennaRNA/include \ + /opt/ViennaRNA/include \ + ;\ + do + if test -r "$ac_dir/part_func.h"; then + ac_VRNA_includes=$ac_dir + break + fi + done +fi +if test $ac_VRNA_includes; then + CPPFLAGS="$CPPFLAGS -I$ac_VRNA_includes" +fi + +if [ -d ../lib ] && [ "$ac_VRNA_includes" = "../H" ]; then + ac_VRNA_lib=../lib +fi + +if test -z "$ac_VRNA_lib"; then +for ac_dir in `echo "$ac_VRNA_includes" | sed -e s/include/lib/ -e s/H$/lib/` \ + /usr/local/lib \ + ; \ +do + for ac_extension in a so sl; do + if test -r $ac_dir/libRNA.$ac_extension; then + ac_VRNA_lib=$ac_dir + break 2 + fi + done +done +fi # $ac_VRNA_lib = NO +if test $ac_VRNA_lib; then + LDFLAGS="-L$ac_VRNA_lib $LDFLAGS" +fi +echo "$as_me:$LINENO: result: headers in \"$ac_VRNA_includes\" and library... \"$ac_VRNA_lib\"" >&5 +echo "${ECHO_T} headers in \"$ac_VRNA_includes\" and library... \"$ac_VRNA_lib\"" >&6 + + + + + +echo "$as_me:$LINENO: checking for exp in -lm" >&5 +echo $ECHO_N "checking for exp in -lm... $ECHO_C" >&6 +if test "${ac_cv_lib_m_exp+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lm $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char exp (); +int +main () +{ +exp (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_m_exp=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_m_exp=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_m_exp" >&5 +echo "${ECHO_T}$ac_cv_lib_m_exp" >&6 +if test $ac_cv_lib_m_exp = yes; then + cat >>confdefs.h <<_ACEOF +#define HAVE_LIBM 1 +_ACEOF + + LIBS="-lm $LIBS" + +fi + + +LIBS="-lRNA ${LIBS}" + + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +echo "$as_me:$LINENO: checking how to run the C preprocessor" >&5 +echo $ECHO_N "checking how to run the C preprocessor... $ECHO_C" >&6 +# On Suns, sometimes $CPP names a directory. +if test -n "$CPP" && test -d "$CPP"; then + CPP= +fi +if test -z "$CPP"; then + if test "${ac_cv_prog_CPP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # Double quotes because CPP needs to be expanded + for CPP in "$CC -E" "$CC -E -traditional-cpp" "/lib/cpp" + do + ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + break +fi + + done + ac_cv_prog_CPP=$CPP + +fi + CPP=$ac_cv_prog_CPP +else + ac_cv_prog_CPP=$CPP +fi +echo "$as_me:$LINENO: result: $CPP" >&5 +echo "${ECHO_T}$CPP" >&6 +ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + : +else + { { echo "$as_me:$LINENO: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&5 +echo "$as_me: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + + +echo "$as_me:$LINENO: checking for egrep" >&5 +echo $ECHO_N "checking for egrep... $ECHO_C" >&6 +if test "${ac_cv_prog_egrep+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if echo a | (grep -E '(a|b)') >/dev/null 2>&1 + then ac_cv_prog_egrep='grep -E' + else ac_cv_prog_egrep='egrep' + fi +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5 +echo "${ECHO_T}$ac_cv_prog_egrep" >&6 + EGREP=$ac_cv_prog_egrep + + +echo "$as_me:$LINENO: checking for ANSI C header files" >&5 +echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6 +if test "${ac_cv_header_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_header_stdc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_header_stdc=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + +if test $ac_cv_header_stdc = yes; then + # SunOS 4.x string.h does not declare mem*, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "memchr" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "free" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi. + if test "$cross_compiling" = yes; then + : +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#if ((' ' & 0x0FF) == 0x020) +# define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +#else +# define ISLOWER(c) \ + (('a' <= (c) && (c) <= 'i') \ + || ('j' <= (c) && (c) <= 'r') \ + || ('s' <= (c) && (c) <= 'z')) +# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +#endif + +#define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +int +main () +{ + int i; + for (i = 0; i < 256; i++) + if (XOR (islower (i), ISLOWER (i)) + || toupper (i) != TOUPPER (i)) + exit(2); + exit (0); +} +_ACEOF +rm -f conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && { ac_try='./conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: program exited with status $ac_status" >&5 +echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +( exit $ac_status ) +ac_cv_header_stdc=no +fi +rm -f core *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext +fi +fi +fi +echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5 +echo "${ECHO_T}$ac_cv_header_stdc" >&6 +if test $ac_cv_header_stdc = yes; then + +cat >>confdefs.h <<\_ACEOF +#define STDC_HEADERS 1 +_ACEOF + +fi + +# On IRIX 5.3, sys/types and inttypes.h are conflicting. + + + + + + + + + +for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default + +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_Header=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_Header=no" +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + + + + +for ac_header in limits.h sys/time.h unistd.h fold.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +else + # Is the header compilable? +echo "$as_me:$LINENO: checking $ac_header usability" >&5 +echo $ECHO_N "checking $ac_header usability... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_header_compiler=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_header_compiler=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_compiler" >&5 +echo "${ECHO_T}$ac_header_compiler" >&6 + +# Is the header present? +echo "$as_me:$LINENO: checking $ac_header presence" >&5 +echo $ECHO_N "checking $ac_header presence... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include <$ac_header> +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + ac_header_preproc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + ac_header_preproc=no +fi +rm -f conftest.err conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_preproc" >&5 +echo "${ECHO_T}$ac_header_preproc" >&6 + +# So? What about this header? +case $ac_header_compiler:$ac_header_preproc:$ac_c_preproc_warn_flag in + yes:no: ) + { echo "$as_me:$LINENO: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&5 +echo "$as_me: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the compiler's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the compiler's result" >&2;} + ac_header_preproc=yes + ;; + no:yes:* ) + { echo "$as_me:$LINENO: WARNING: $ac_header: present but cannot be compiled" >&5 +echo "$as_me: WARNING: $ac_header: present but cannot be compiled" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: check for missing prerequisite headers?" >&5 +echo "$as_me: WARNING: $ac_header: check for missing prerequisite headers?" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: see the Autoconf documentation" >&5 +echo "$as_me: WARNING: $ac_header: see the Autoconf documentation" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&5 +echo "$as_me: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the preprocessor's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the preprocessor's result" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: in the future, the compiler will take precedence" >&5 +echo "$as_me: WARNING: $ac_header: in the future, the compiler will take precedence" >&2;} + ( + cat <<\_ASBOX +## ----------------------------------- ## +## Report this to rna@tbi.univie.ac.at ## +## ----------------------------------- ## +_ASBOX + ) | + sed "s/^/$as_me: WARNING: /" >&2 + ;; +esac +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + eval "$as_ac_Header=\$ac_header_preproc" +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 + +fi +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + +echo "$as_me:$LINENO: checking for an ANSI C-conforming const" >&5 +echo $ECHO_N "checking for an ANSI C-conforming const... $ECHO_C" >&6 +if test "${ac_cv_c_const+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +/* FIXME: Include the comments suggested by Paul. */ +#ifndef __cplusplus + /* Ultrix mips cc rejects this. */ + typedef int charset[2]; + const charset x; + /* SunOS 4.1.1 cc rejects this. */ + char const *const *ccp; + char **p; + /* NEC SVR4.0.2 mips cc rejects this. */ + struct point {int x, y;}; + static struct point const zero = {0,0}; + /* AIX XL C 1.02.0.0 rejects this. + It does not let you subtract one const X* pointer from another in + an arm of an if-expression whose if-part is not a constant + expression */ + const char *g = "string"; + ccp = &g + (g ? g-g : 0); + /* HPUX 7.0 cc rejects these. */ + ++ccp; + p = (char**) ccp; + ccp = (char const *const *) p; + { /* SCO 3.2v4 cc rejects this. */ + char *t; + char const *s = 0 ? (char *) 0 : (char const *) 0; + + *t++ = 0; + } + { /* Someone thinks the Sun supposedly-ANSI compiler will reject this. */ + int x[] = {25, 17}; + const int *foo = &x[0]; + ++foo; + } + { /* Sun SC1.0 ANSI compiler rejects this -- but not the above. */ + typedef const int *iptr; + iptr p = 0; + ++p; + } + { /* AIX XL C 1.02.0.0 rejects this saying + "k.c", line 2.27: 1506-025 (S) Operand must be a modifiable lvalue. */ + struct s { int j; const int *ap[3]; }; + struct s *b; b->j = 5; + } + { /* ULTRIX-32 V3.1 (Rev 9) vcc rejects this */ + const int foo = 10; + } +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_c_const=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_c_const=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_c_const" >&5 +echo "${ECHO_T}$ac_cv_c_const" >&6 +if test $ac_cv_c_const = no; then + +cat >>confdefs.h <<\_ACEOF +#define const +_ACEOF + +fi + + + +for ac_func in strdup +do +as_ac_var=`echo "ac_cv_func_$ac_func" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_func" >&5 +echo $ECHO_N "checking for $ac_func... $ECHO_C" >&6 +if eval "test \"\${$as_ac_var+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define $ac_func to an innocuous variant, in case declares $ac_func. + For example, HP-UX 11i declares gettimeofday. */ +#define $ac_func innocuous_$ac_func + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char $ac_func (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef $ac_func + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char $ac_func (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_$ac_func) || defined (__stub___$ac_func) +choke me +#else +char (*f) () = $ac_func; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != $ac_func; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_var=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_var=no" +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_var'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_var'}'`" >&6 +if test `eval echo '${'$as_ac_var'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_func" | $as_tr_cpp` 1 +_ACEOF + +fi +done + + + ac_config_files="$ac_config_files Makefile Example/Makefile" +cat >confcache <<\_ACEOF +# This file is a shell script that caches the results of configure +# tests run on this system so they can be shared between configure +# scripts and configure runs, see configure's option --config-cache. +# It is not useful on other systems. If it contains results you don't +# want to keep, you may remove or edit it. +# +# config.status only pays attention to the cache file if you give it +# the --recheck option to rerun configure. +# +# `ac_cv_env_foo' variables (set or unset) will be overridden when +# loading this file, other *unset* `ac_cv_foo' will be assigned the +# following values. + +_ACEOF + +# The following way of writing the cache mishandles newlines in values, +# but we know of no workaround that is simple, portable, and efficient. +# So, don't put newlines in cache variables' values. +# Ultrix sh set writes to stderr and can't be redirected directly, +# and sets the high bit in the cache file unless we assign to the vars. +{ + (set) 2>&1 | + case `(ac_space=' '; set | grep ac_space) 2>&1` in + *ac_space=\ *) + # `set' does not quote correctly, so add quotes (double-quote + # substitution turns \\\\ into \\, and sed turns \\ into \). + sed -n \ + "s/'/'\\\\''/g; + s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='\\2'/p" + ;; + *) + # `set' quotes correctly as required by POSIX, so do not add quotes. + sed -n \ + "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p" + ;; + esac; +} | + sed ' + t clear + : clear + s/^\([^=]*\)=\(.*[{}].*\)$/test "${\1+set}" = set || &/ + t end + /^ac_cv_env/!s/^\([^=]*\)=\(.*\)$/\1=${\1=\2}/ + : end' >>confcache +if diff $cache_file confcache >/dev/null 2>&1; then :; else + if test -w $cache_file; then + test "x$cache_file" != "x/dev/null" && echo "updating cache $cache_file" + cat confcache >$cache_file + else + echo "not updating unwritable cache $cache_file" + fi +fi +rm -f confcache + +test "x$prefix" = xNONE && prefix=$ac_default_prefix +# Let make expand exec_prefix. +test "x$exec_prefix" = xNONE && exec_prefix='${prefix}' + +# VPATH may cause trouble with some makes, so we remove $(srcdir), +# ${srcdir} and @srcdir@ from VPATH if srcdir is ".", strip leading and +# trailing colons and then remove the whole line if VPATH becomes empty +# (actually we leave an empty line to preserve line numbers). +if test "x$srcdir" = x.; then + ac_vpsub='/^[ ]*VPATH[ ]*=/{ +s/:*\$(srcdir):*/:/; +s/:*\${srcdir}:*/:/; +s/:*@srcdir@:*/:/; +s/^\([^=]*=[ ]*\):*/\1/; +s/:*$//; +s/^[^=]*=[ ]*$//; +}' +fi + +DEFS=-DHAVE_CONFIG_H + +ac_libobjs= +ac_ltlibobjs= +for ac_i in : $LIBOBJS; do test "x$ac_i" = x: && continue + # 1. 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Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +_ACEOF + +# Files that config.status was made for. +if test -n "$ac_config_files"; then + echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_headers"; then + echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_links"; then + echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_commands"; then + echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS +fi + +cat >>$CONFIG_STATUS <<\_ACEOF + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF +ac_cs_version="\\ +Kinfold config.status 1.0 +configured by $0, generated by GNU Autoconf 2.59, + with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=$srcdir +INSTALL="$INSTALL" +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +# If no file are specified by the user, then we need to provide default +# value. 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Make it in the build tree +# simply because there is no reason to put it here, and in addition, +# creating and moving files from /tmp can sometimes cause problems. +# Create a temporary directory, and hook for its removal unless debugging. +$debug || +{ + trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0 + trap '{ (exit 1); exit 1; }' 1 2 13 15 +} + +# Create a (secure) tmp directory for tmp files. + +{ + tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` && + test -n "$tmp" && test -d "$tmp" +} || +{ + tmp=./confstat$$-$RANDOM + (umask 077 && mkdir $tmp) +} || +{ + echo "$me: cannot create a temporary directory in ." >&2 + { (exit 1); exit 1; } +} + +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF + +# +# CONFIG_FILES section. +# + +# No need to generate the scripts if there are no CONFIG_FILES. +# This happens for instance when ./config.status config.h +if test -n "\$CONFIG_FILES"; then + # Protect against being on the right side of a sed subst in config.status. + sed 's/,@/@@/; s/@,/@@/; s/,;t t\$/@;t t/; /@;t t\$/s/[\\\\&,]/\\\\&/g; + s/@@/,@/; s/@@/@,/; s/@;t t\$/,;t t/' >\$tmp/subs.sed <<\\CEOF +s,@SHELL@,$SHELL,;t t +s,@PATH_SEPARATOR@,$PATH_SEPARATOR,;t t +s,@PACKAGE_NAME@,$PACKAGE_NAME,;t t +s,@PACKAGE_TARNAME@,$PACKAGE_TARNAME,;t t +s,@PACKAGE_VERSION@,$PACKAGE_VERSION,;t t +s,@PACKAGE_STRING@,$PACKAGE_STRING,;t t +s,@PACKAGE_BUGREPORT@,$PACKAGE_BUGREPORT,;t t +s,@exec_prefix@,$exec_prefix,;t t +s,@prefix@,$prefix,;t t +s,@program_transform_name@,$program_transform_name,;t t +s,@bindir@,$bindir,;t t +s,@sbindir@,$sbindir,;t t +s,@libexecdir@,$libexecdir,;t t +s,@datadir@,$datadir,;t t +s,@sysconfdir@,$sysconfdir,;t t +s,@sharedstatedir@,$sharedstatedir,;t t +s,@localstatedir@,$localstatedir,;t t +s,@libdir@,$libdir,;t t +s,@includedir@,$includedir,;t t +s,@oldincludedir@,$oldincludedir,;t t +s,@infodir@,$infodir,;t t +s,@mandir@,$mandir,;t t +s,@build_alias@,$build_alias,;t t +s,@host_alias@,$host_alias,;t t +s,@target_alias@,$target_alias,;t t +s,@DEFS@,$DEFS,;t t +s,@ECHO_C@,$ECHO_C,;t t +s,@ECHO_N@,$ECHO_N,;t t +s,@ECHO_T@,$ECHO_T,;t t +s,@LIBS@,$LIBS,;t t +s,@INSTALL_PROGRAM@,$INSTALL_PROGRAM,;t t +s,@INSTALL_SCRIPT@,$INSTALL_SCRIPT,;t t +s,@INSTALL_DATA@,$INSTALL_DATA,;t t +s,@CYGPATH_W@,$CYGPATH_W,;t t +s,@PACKAGE@,$PACKAGE,;t t +s,@VERSION@,$VERSION,;t t +s,@ACLOCAL@,$ACLOCAL,;t t +s,@AUTOCONF@,$AUTOCONF,;t t +s,@AUTOMAKE@,$AUTOMAKE,;t t +s,@AUTOHEADER@,$AUTOHEADER,;t t +s,@MAKEINFO@,$MAKEINFO,;t t +s,@install_sh@,$install_sh,;t t +s,@STRIP@,$STRIP,;t t +s,@ac_ct_STRIP@,$ac_ct_STRIP,;t t +s,@INSTALL_STRIP_PROGRAM@,$INSTALL_STRIP_PROGRAM,;t t +s,@mkdir_p@,$mkdir_p,;t t +s,@AWK@,$AWK,;t t +s,@SET_MAKE@,$SET_MAKE,;t t +s,@am__leading_dot@,$am__leading_dot,;t t +s,@AMTAR@,$AMTAR,;t t +s,@am__tar@,$am__tar,;t t +s,@am__untar@,$am__untar,;t t +s,@CC@,$CC,;t t +s,@CFLAGS@,$CFLAGS,;t t +s,@LDFLAGS@,$LDFLAGS,;t t +s,@CPPFLAGS@,$CPPFLAGS,;t t +s,@ac_ct_CC@,$ac_ct_CC,;t t +s,@EXEEXT@,$EXEEXT,;t t +s,@OBJEXT@,$OBJEXT,;t t +s,@DEPDIR@,$DEPDIR,;t t +s,@am__include@,$am__include,;t t +s,@am__quote@,$am__quote,;t t +s,@AMDEP_TRUE@,$AMDEP_TRUE,;t t +s,@AMDEP_FALSE@,$AMDEP_FALSE,;t t +s,@AMDEPBACKSLASH@,$AMDEPBACKSLASH,;t t +s,@CCDEPMODE@,$CCDEPMODE,;t t +s,@am__fastdepCC_TRUE@,$am__fastdepCC_TRUE,;t t +s,@am__fastdepCC_FALSE@,$am__fastdepCC_FALSE,;t t +s,@ISODATE@,$ISODATE,;t t +s,@build@,$build,;t t +s,@build_cpu@,$build_cpu,;t t +s,@build_vendor@,$build_vendor,;t t +s,@build_os@,$build_os,;t t +s,@host@,$host,;t t +s,@host_cpu@,$host_cpu,;t t +s,@host_vendor@,$host_vendor,;t t +s,@host_os@,$host_os,;t t +s,@CPP@,$CPP,;t t +s,@EGREP@,$EGREP,;t t +s,@LIBOBJS@,$LIBOBJS,;t t +s,@LTLIBOBJS@,$LTLIBOBJS,;t t +CEOF + +_ACEOF + + cat >>$CONFIG_STATUS <<\_ACEOF + # Split the substitutions into bite-sized pieces for seds with + # small command number limits, like on Digital OSF/1 and HP-UX. + ac_max_sed_lines=48 + ac_sed_frag=1 # Number of current file. + ac_beg=1 # First line for current file. + ac_end=$ac_max_sed_lines # Line after last line for current file. + ac_more_lines=: + ac_sed_cmds= + while $ac_more_lines; do + if test $ac_beg -gt 1; then + sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + else + sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + fi + if test ! 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Generated by config.status. */ + if test x"$ac_file" = x-; then + configure_input= + else + configure_input="$ac_file. " + fi + configure_input=$configure_input"Generated from `echo $ac_file_in | + sed 's,.*/,,'` by configure." + + # First look for the input files in the build tree, otherwise in the + # src tree. + ac_file_inputs=`IFS=: + for f in $ac_file_in; do + case $f in + -) echo $tmp/stdin ;; + [\\/$]*) + # Absolute (can't be DOS-style, as IFS=:) + test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + echo "$f";; + *) # Relative + if test -f "$f"; then + # Build tree + echo "$f" + elif test -f "$srcdir/$f"; then + # Source tree + echo "$srcdir/$f" + else + # /dev/null tree + { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + fi;; + esac + done` || { (exit 1); exit 1; } +_ACEOF +cat >>$CONFIG_STATUS <<_ACEOF + sed "$ac_vpsub +$extrasub +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF +:t +/@[a-zA-Z_][a-zA-Z_0-9]*@/!b +s,@configure_input@,$configure_input,;t t +s,@srcdir@,$ac_srcdir,;t t +s,@abs_srcdir@,$ac_abs_srcdir,;t t +s,@top_srcdir@,$ac_top_srcdir,;t t +s,@abs_top_srcdir@,$ac_abs_top_srcdir,;t t +s,@builddir@,$ac_builddir,;t t +s,@abs_builddir@,$ac_abs_builddir,;t t +s,@top_builddir@,$ac_top_builddir,;t t +s,@abs_top_builddir@,$ac_abs_top_builddir,;t t +s,@INSTALL@,$ac_INSTALL,;t t +" $ac_file_inputs | (eval "$ac_sed_cmds") >$tmp/out + rm -f $tmp/stdin + if test x"$ac_file" != x-; then + mv $tmp/out $ac_file + else + cat $tmp/out + rm -f $tmp/out + fi + +done +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF + +# +# CONFIG_HEADER section. +# + +# These sed commands are passed to sed as "A NAME B NAME C VALUE D", where +# NAME is the cpp macro being defined and VALUE is the value it is being given. +# +# ac_d sets the value in "#define NAME VALUE" lines. +ac_dA='s,^\([ ]*\)#\([ ]*define[ ][ ]*\)' +ac_dB='[ ].*$,\1#\2' +ac_dC=' ' +ac_dD=',;t' +# ac_u turns "#undef NAME" without trailing blanks into "#define NAME VALUE". +ac_uA='s,^\([ ]*\)#\([ ]*\)undef\([ ][ ]*\)' +ac_uB='$,\1#\2define\3' +ac_uC=' ' +ac_uD=',;t' + +for ac_file in : $CONFIG_HEADERS; do test "x$ac_file" = x: && continue + # Support "outfile[:infile[:infile...]]", defaulting infile="outfile.in". + case $ac_file in + - | *:- | *:-:* ) # input from stdin + cat >$tmp/stdin + ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + *:* ) ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + * ) ac_file_in=$ac_file.in ;; + esac + + test x"$ac_file" != x- && { echo "$as_me:$LINENO: creating $ac_file" >&5 +echo "$as_me: creating $ac_file" >&6;} + + # First look for the input files in the build tree, otherwise in the + # src tree. + ac_file_inputs=`IFS=: + for f in $ac_file_in; do + case $f in + -) echo $tmp/stdin ;; + [\\/$]*) + # Absolute (can't be DOS-style, as IFS=:) + test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + # Do quote $f, to prevent DOS paths from being IFS'd. + echo "$f";; + *) # Relative + if test -f "$f"; then + # Build tree + echo "$f" + elif test -f "$srcdir/$f"; then + # Source tree + echo "$srcdir/$f" + else + # /dev/null tree + { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + fi;; + esac + done` || { (exit 1); exit 1; } + # Remove the trailing spaces. + sed 's/[ ]*$//' $ac_file_inputs >$tmp/in + +_ACEOF + +# Transform confdefs.h into two sed scripts, `conftest.defines' and +# `conftest.undefs', that substitutes the proper values into +# config.h.in to produce config.h. The first handles `#define' +# templates, and the second `#undef' templates. +# And first: Protect against being on the right side of a sed subst in +# config.status. Protect against being in an unquoted here document +# in config.status. +rm -f conftest.defines conftest.undefs +# Using a here document instead of a string reduces the quoting nightmare. +# Putting comments in sed scripts is not portable. +# +# `end' is used to avoid that the second main sed command (meant for +# 0-ary CPP macros) applies to n-ary macro definitions. +# See the Autoconf documentation for `clear'. +cat >confdef2sed.sed <<\_ACEOF +s/[\\&,]/\\&/g +s,[\\$`],\\&,g +t clear +: clear +s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*\)\(([^)]*)\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1\2${ac_dC}\3${ac_dD},gp +t end +s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1${ac_dC}\2${ac_dD},gp +: end +_ACEOF +# If some macros were called several times there might be several times +# the same #defines, which is useless. Nevertheless, we may not want to +# sort them, since we want the *last* AC-DEFINE to be honored. +uniq confdefs.h | sed -n -f confdef2sed.sed >conftest.defines +sed 's/ac_d/ac_u/g' conftest.defines >conftest.undefs +rm -f confdef2sed.sed + +# This sed command replaces #undef with comments. This is necessary, for +# example, in the case of _POSIX_SOURCE, which is predefined and required +# on some systems where configure will not decide to define it. +cat >>conftest.undefs <<\_ACEOF +s,^[ ]*#[ ]*undef[ ][ ]*[a-zA-Z_][a-zA-Z_0-9]*,/* & */, +_ACEOF + +# Break up conftest.defines because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #define templates only if necessary.' >>$CONFIG_STATUS +echo ' if grep "^[ ]*#[ ]*define" $tmp/in >/dev/null; then' >>$CONFIG_STATUS +echo ' # If there are no defines, we may have an empty if/fi' >>$CONFIG_STATUS +echo ' :' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.defines >/dev/null +do + # Write a limited-size here document to $tmp/defines.sed. + echo ' cat >$tmp/defines.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#define' lines. + echo '/^[ ]*#[ ]*define/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.defines >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/defines.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.defines >conftest.tail + rm -f conftest.defines + mv conftest.tail conftest.defines +done +rm -f conftest.defines +echo ' fi # grep' >>$CONFIG_STATUS +echo >>$CONFIG_STATUS + +# Break up conftest.undefs because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #undef templates' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.undefs >/dev/null +do + # Write a limited-size here document to $tmp/undefs.sed. + echo ' cat >$tmp/undefs.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#undef' + echo '/^[ ]*#[ ]*undef/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.undefs >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/undefs.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.undefs >conftest.tail + rm -f conftest.undefs + mv conftest.tail conftest.undefs +done +rm -f conftest.undefs + +cat >>$CONFIG_STATUS <<\_ACEOF + # Let's still pretend it is `configure' which instantiates (i.e., don't + # use $as_me), people would be surprised to read: + # /* config.h. Generated by config.status. */ + if test x"$ac_file" = x-; then + echo "/* Generated by configure. */" >$tmp/config.h + else + echo "/* $ac_file. Generated by configure. */" >$tmp/config.h + fi + cat $tmp/in >>$tmp/config.h + rm -f $tmp/in + if test x"$ac_file" != x-; then + if diff $ac_file $tmp/config.h >/dev/null 2>&1; then + { echo "$as_me:$LINENO: $ac_file is unchanged" >&5 +echo "$as_me: $ac_file is unchanged" >&6;} + else + ac_dir=`(dirname "$ac_file") 2>/dev/null || +$as_expr X"$ac_file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$ac_file" : 'X\(//\)[^/]' \| \ + X"$ac_file" : 'X\(//\)$' \| \ + X"$ac_file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$ac_file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + rm -f $ac_file + mv $tmp/config.h $ac_file + fi + else + cat $tmp/config.h + rm -f $tmp/config.h + fi +# Compute $ac_file's index in $config_headers. +_am_stamp_count=1 +for _am_header in $config_headers :; do + case $_am_header in + $ac_file | $ac_file:* ) + break ;; + * ) + _am_stamp_count=`expr $_am_stamp_count + 1` ;; + esac +done +echo "timestamp for $ac_file" >`(dirname $ac_file) 2>/dev/null || +$as_expr X$ac_file : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X$ac_file : 'X\(//\)[^/]' \| \ + X$ac_file : 'X\(//\)$' \| \ + X$ac_file : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X$ac_file | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'`/stamp-h$_am_stamp_count +done +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF + +# +# CONFIG_COMMANDS section. +# +for ac_file in : $CONFIG_COMMANDS; do test "x$ac_file" = x: && continue + ac_dest=`echo "$ac_file" | sed 's,:.*,,'` + ac_source=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_dir=`(dirname "$ac_dest") 2>/dev/null || +$as_expr X"$ac_dest" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$ac_dest" : 'X\(//\)[^/]' \| \ + X"$ac_dest" : 'X\(//\)$' \| \ + X"$ac_dest" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$ac_dest" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. We are building in place. + ac_srcdir=. + if test -z "$ac_top_builddir"; then + ac_top_srcdir=. + else + ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'` + fi ;; + [\\/]* | ?:[\\/]* ) # Absolute path. + ac_srcdir=$srcdir$ac_dir_suffix; + ac_top_srcdir=$srcdir ;; + *) # Relative path. + ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix + ac_top_srcdir=$ac_top_builddir$srcdir ;; +esac + +# Do not use `cd foo && pwd` to compute absolute paths, because +# the directories may not exist. +case `pwd` in +.) ac_abs_builddir="$ac_dir";; +*) + case "$ac_dir" in + .) ac_abs_builddir=`pwd`;; + [\\/]* | ?:[\\/]* ) ac_abs_builddir="$ac_dir";; + *) ac_abs_builddir=`pwd`/"$ac_dir";; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_builddir=${ac_top_builddir}.;; +*) + case ${ac_top_builddir}. in + .) ac_abs_top_builddir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_builddir=${ac_top_builddir}.;; + *) ac_abs_top_builddir=$ac_abs_builddir/${ac_top_builddir}.;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_srcdir=$ac_srcdir;; +*) + case $ac_srcdir in + .) ac_abs_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_srcdir=$ac_srcdir;; + *) ac_abs_srcdir=$ac_abs_builddir/$ac_srcdir;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_srcdir=$ac_top_srcdir;; +*) + case $ac_top_srcdir in + .) ac_abs_top_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_srcdir=$ac_top_srcdir;; + *) ac_abs_top_srcdir=$ac_abs_builddir/$ac_top_srcdir;; + esac;; +esac + + + { echo "$as_me:$LINENO: executing $ac_dest commands" >&5 +echo "$as_me: executing $ac_dest commands" >&6;} + case $ac_dest in + depfiles ) test x"$AMDEP_TRUE" != x"" || for mf in $CONFIG_FILES; do + # Strip MF so we end up with the name of the file. + mf=`echo "$mf" | sed -e 's/:.*$//'` + # Check whether this is an Automake generated Makefile or not. + # We used to match only the files named `Makefile.in', but + # some people rename them; so instead we look at the file content. + # Grep'ing the first line is not enough: some people post-process + # each Makefile.in and add a new line on top of each file to say so. + # So let's grep whole file. + if grep '^#.*generated by automake' $mf > /dev/null 2>&1; then + dirpart=`(dirname "$mf") 2>/dev/null || +$as_expr X"$mf" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$mf" : 'X\(//\)[^/]' \| \ + X"$mf" : 'X\(//\)$' \| \ + X"$mf" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$mf" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + else + continue + fi + # Extract the definition of DEPDIR, am__include, and am__quote + # from the Makefile without running `make'. + DEPDIR=`sed -n 's/^DEPDIR = //p' < "$mf"` + test -z "$DEPDIR" && continue + am__include=`sed -n 's/^am__include = //p' < "$mf"` + test -z "am__include" && continue + am__quote=`sed -n 's/^am__quote = //p' < "$mf"` + # When using ansi2knr, U may be empty or an underscore; expand it + U=`sed -n 's/^U = //p' < "$mf"` + # Find all dependency output files, they are included files with + # $(DEPDIR) in their names. We invoke sed twice because it is the + # simplest approach to changing $(DEPDIR) to its actual value in the + # expansion. + for file in `sed -n " + s/^$am__include $am__quote\(.*(DEPDIR).*\)$am__quote"'$/\1/p' <"$mf" | \ + sed -e 's/\$(DEPDIR)/'"$DEPDIR"'/g' -e 's/\$U/'"$U"'/g'`; do + # Make sure the directory exists. + test -f "$dirpart/$file" && continue + fdir=`(dirname "$file") 2>/dev/null || +$as_expr X"$file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$file" : 'X\(//\)[^/]' \| \ + X"$file" : 'X\(//\)$' \| \ + X"$file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p $dirpart/$fdir + else + as_dir=$dirpart/$fdir + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory $dirpart/$fdir" >&5 +echo "$as_me: error: cannot create directory $dirpart/$fdir" >&2;} + { (exit 1); exit 1; }; }; } + + # echo "creating $dirpart/$file" + echo '# dummy' > "$dirpart/$file" + done +done + ;; + esac +done +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF + +{ (exit 0); exit 0; } +_ACEOF +chmod +x $CONFIG_STATUS +ac_clean_files=$ac_clean_files_save + + +# configure is writing to config.log, and then calls config.status. +# config.status does its own redirection, appending to config.log. +# Unfortunately, on DOS this fails, as config.log is still kept open +# by configure, so config.status won't be able to write to it; its +# output is simply discarded. So we exec the FD to /dev/null, +# effectively closing config.log, so it can be properly (re)opened and +# appended to by config.status. When coming back to configure, we +# need to make the FD available again. +if test "$no_create" != yes; then + ac_cs_success=: + ac_config_status_args= + test "$silent" = yes && + ac_config_status_args="$ac_config_status_args --quiet" + exec 5>/dev/null + $SHELL $CONFIG_STATUS $ac_config_status_args || ac_cs_success=false + exec 5>>config.log + # Use ||, not &&, to avoid exiting from the if with $? = 1, which + # would make configure fail if this is the last instruction. + $ac_cs_success || { (exit 1); exit 1; } +fi + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/configure.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/configure.in new file mode 100755 index 00000000..d1dad181 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/configure.in @@ -0,0 +1,55 @@ +dnl Process this file with autoconf to produce a configure script. +AC_INIT([Kinfold], [1.0], [rna@tbi.univie.ac.at]) + +dnl Every other copy of the package version number gets its value from here +AM_INIT_AUTOMAKE + +dnl configure options +AM_WITH_DMALLOC + +dnl Checks for programs. +AC_PROG_CC +AC_PROG_MAKE_SET + +dnl create a config.h file (Automake will add -DHAVE_CONFIG_H) +AM_CONFIG_HEADER(config.h) + +AC_SUBST(VERSION) + +ISODATE=`date +%Y-%m-%d` +AC_SUBST(ISODATE) + +AC_CANONICAL_HOST + +AC_ARG_WITH(ViennaRNA-include, + [ --with-ViennaRNA-include where to search for ViennaRNA header files], + ac_VRNA_includes="$withval", + ) + +AC_ARG_WITH(ViennaRNA-lib, + [ --with-ViennaRNA-lib where to search for libRNA.a], + ac_VRNA_lib="$withval", + ) + +AC_PATH_VRNA + +dnl Checks for libraries. +dnl Replace `main' with a function in -lm: +AC_CHECK_LIB(m, exp) + +dnl checking for -lRNA will fail if both are built simultaneously +dnl AC_CHECK_LIB(RNA, fold) +LIBS=["-lRNA ${LIBS}"] + + +dnl Checks for header files. +AC_HEADER_STDC +AC_CHECK_HEADERS(limits.h sys/time.h unistd.h fold.h) + +dnl Checks for typedefs, structures, and compiler characteristics. +AC_C_CONST + +dnl Checks for library functions. +AC_CHECK_FUNCS(strdup) + +AC_OUTPUT(Makefile Example/Makefile) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.c new file mode 100755 index 00000000..4744e433 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.c @@ -0,0 +1,1055 @@ +/* Getopt for GNU. + NOTE: getopt is now part of the C library, so if you don't know what + "Keep this file name-space clean" means, talk to drepper@gnu.org + before changing it! + + Copyright (C) 1987, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 2000 + Free Software Foundation, Inc. + + The GNU C Library is free software; you can redistribute it and/or + modify it under the terms of the GNU Library General Public License as + published by the Free Software Foundation; either version 2 of the + License, or (at your option) any later version. + + The GNU C Library is distributed in the hope that it will be useful, + but WITHOUT ANY WARRANTY; without even the implied warranty of + MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU + Library General Public License for more details. + + You should have received a copy of the GNU Library General Public + License along with the GNU C Library; see the file COPYING.LIB. If not, + write to the Free Software Foundation, Inc., 59 Temple Place - Suite 330, + Boston, MA 02111-1307, USA. */ + +/* This tells Alpha OSF/1 not to define a getopt prototype in . + Ditto for AIX 3.2 and . */ +#ifndef _NO_PROTO +# define _NO_PROTO +#endif + +#ifdef HAVE_CONFIG_H +# include +#endif + +#if !defined __STDC__ || !__STDC__ +/* This is a separate conditional since some stdc systems + reject `defined (const)'. */ +# ifndef const +# define const +# endif +#endif + +#include + +/* Comment out all this code if we are using the GNU C Library, and are not + actually compiling the library itself. This code is part of the GNU C + Library, but also included in many other GNU distributions. Compiling + and linking in this code is a waste when using the GNU C library + (especially if it is a shared library). Rather than having every GNU + program understand `configure --with-gnu-libc' and omit the object files, + it is simpler to just do this in the source for each such file. */ + +#define GETOPT_INTERFACE_VERSION 2 +#if !defined _LIBC && defined __GLIBC__ && __GLIBC__ >= 2 +# include +# if _GNU_GETOPT_INTERFACE_VERSION == GETOPT_INTERFACE_VERSION +# define ELIDE_CODE +# endif +#endif + +#ifndef ELIDE_CODE + + +/* This needs to come after some library #include + to get __GNU_LIBRARY__ defined. */ +#ifdef __GNU_LIBRARY__ +/* Don't include stdlib.h for non-GNU C libraries because some of them + contain conflicting prototypes for getopt. */ +# include +# include +#endif /* GNU C library. */ + +#ifdef VMS +# include +# if HAVE_STRING_H - 0 +# include +# endif +#endif + +#ifndef _ +/* This is for other GNU distributions with internationalized messages. + When compiling libc, the _ macro is predefined. */ +# ifdef HAVE_LIBINTL_H +# include +# define _(msgid) gettext (msgid) +# else +# define _(msgid) (msgid) +# endif +#endif + +/* This version of `getopt' appears to the caller like standard Unix `getopt' + but it behaves differently for the user, since it allows the user + to intersperse the options with the other arguments. + + As `getopt' works, it permutes the elements of ARGV so that, + when it is done, all the options precede everything else. Thus + all application programs are extended to handle flexible argument order. + + Setting the environment variable POSIXLY_CORRECT disables permutation. + Then the behavior is completely standard. + + GNU application programs can use a third alternative mode in which + they can distinguish the relative order of options and other arguments. */ + +#include "getopt.h" + +/* For communication from `getopt' to the caller. + When `getopt' finds an option that takes an argument, + the argument value is returned here. + Also, when `ordering' is RETURN_IN_ORDER, + each non-option ARGV-element is returned here. */ + +char *optarg; + +/* Index in ARGV of the next element to be scanned. + This is used for communication to and from the caller + and for communication between successive calls to `getopt'. + + On entry to `getopt', zero means this is the first call; initialize. + + When `getopt' returns -1, this is the index of the first of the + non-option elements that the caller should itself scan. + + Otherwise, `optind' communicates from one call to the next + how much of ARGV has been scanned so far. */ + +/* 1003.2 says this must be 1 before any call. */ +int optind = 1; + +/* Formerly, initialization of getopt depended on optind==0, which + causes problems with re-calling getopt as programs generally don't + know that. */ + +int __getopt_initialized; + +/* The next char to be scanned in the option-element + in which the last option character we returned was found. + This allows us to pick up the scan where we left off. + + If this is zero, or a null string, it means resume the scan + by advancing to the next ARGV-element. */ + +static char *nextchar; + +/* Callers store zero here to inhibit the error message + for unrecognized options. */ + +int opterr = 1; + +/* Set to an option character which was unrecognized. + This must be initialized on some systems to avoid linking in the + system's own getopt implementation. */ + +int optopt = '?'; + +/* Describe how to deal with options that follow non-option ARGV-elements. + + If the caller did not specify anything, + the default is REQUIRE_ORDER if the environment variable + POSIXLY_CORRECT is defined, PERMUTE otherwise. + + REQUIRE_ORDER means don't recognize them as options; + stop option processing when the first non-option is seen. + This is what Unix does. + This mode of operation is selected by either setting the environment + variable POSIXLY_CORRECT, or using `+' as the first character + of the list of option characters. + + PERMUTE is the default. We permute the contents of ARGV as we scan, + so that eventually all the non-options are at the end. This allows options + to be given in any order, even with programs that were not written to + expect this. + + RETURN_IN_ORDER is an option available to programs that were written + to expect options and other ARGV-elements in any order and that care about + the ordering of the two. We describe each non-option ARGV-element + as if it were the argument of an option with character code 1. + Using `-' as the first character of the list of option characters + selects this mode of operation. + + The special argument `--' forces an end of option-scanning regardless + of the value of `ordering'. In the case of RETURN_IN_ORDER, only + `--' can cause `getopt' to return -1 with `optind' != ARGC. */ + +static enum +{ + REQUIRE_ORDER, PERMUTE, RETURN_IN_ORDER +} ordering; + +/* Value of POSIXLY_CORRECT environment variable. */ +static char *posixly_correct; + +#ifdef __GNU_LIBRARY__ +/* We want to avoid inclusion of string.h with non-GNU libraries + because there are many ways it can cause trouble. + On some systems, it contains special magic macros that don't work + in GCC. */ +# include +# define my_index strchr +#else + +# if HAVE_STRING_H +# include +# else +# include +# endif + +/* Avoid depending on library functions or files + whose names are inconsistent. */ + +#ifndef getenv +extern char *getenv (); +#endif + +static char * +my_index (str, chr) + const char *str; + int chr; +{ + while (*str) + { + if (*str == chr) + return (char *) str; + str++; + } + return 0; +} + +/* If using GCC, we can safely declare strlen this way. + If not using GCC, it is ok not to declare it. */ +#ifdef __GNUC__ +/* Note that Motorola Delta 68k R3V7 comes with GCC but not stddef.h. + That was relevant to code that was here before. */ +# if (!defined __STDC__ || !__STDC__) && !defined strlen +/* gcc with -traditional declares the built-in strlen to return int, + and has done so at least since version 2.4.5. -- rms. */ +extern int strlen (const char *); +# endif /* not __STDC__ */ +#endif /* __GNUC__ */ + +#endif /* not __GNU_LIBRARY__ */ + +/* Handle permutation of arguments. */ + +/* Describe the part of ARGV that contains non-options that have + been skipped. `first_nonopt' is the index in ARGV of the first of them; + `last_nonopt' is the index after the last of them. */ + +static int first_nonopt; +static int last_nonopt; + +#ifdef _LIBC +/* Bash 2.0 gives us an environment variable containing flags + indicating ARGV elements that should not be considered arguments. */ + +/* Defined in getopt_init.c */ +extern char *__getopt_nonoption_flags; + +static int nonoption_flags_max_len; +static int nonoption_flags_len; + +static int original_argc; +static char *const *original_argv; + +/* Make sure the environment variable bash 2.0 puts in the environment + is valid for the getopt call we must make sure that the ARGV passed + to getopt is that one passed to the process. */ +static void +__attribute__ ((unused)) +store_args_and_env (int argc, char *const *argv) +{ + /* XXX This is no good solution. We should rather copy the args so + that we can compare them later. But we must not use malloc(3). */ + original_argc = argc; + original_argv = argv; +} +# ifdef text_set_element +text_set_element (__libc_subinit, store_args_and_env); +# endif /* text_set_element */ + +# define SWAP_FLAGS(ch1, ch2) \ + if (nonoption_flags_len > 0) \ + { \ + char __tmp = __getopt_nonoption_flags[ch1]; \ + __getopt_nonoption_flags[ch1] = __getopt_nonoption_flags[ch2]; \ + __getopt_nonoption_flags[ch2] = __tmp; \ + } +#else /* !_LIBC */ +# define SWAP_FLAGS(ch1, ch2) +#endif /* _LIBC */ + +/* Exchange two adjacent subsequences of ARGV. + One subsequence is elements [first_nonopt,last_nonopt) + which contains all the non-options that have been skipped so far. + The other is elements [last_nonopt,optind), which contains all + the options processed since those non-options were skipped. + + `first_nonopt' and `last_nonopt' are relocated so that they describe + the new indices of the non-options in ARGV after they are moved. */ + +#if defined __STDC__ && __STDC__ +static void exchange (char **); +#endif + +static void +exchange (argv) + char **argv; +{ + int bottom = first_nonopt; + int middle = last_nonopt; + int top = optind; + char *tem; + + /* Exchange the shorter segment with the far end of the longer segment. + That puts the shorter segment into the right place. + It leaves the longer segment in the right place overall, + but it consists of two parts that need to be swapped next. */ + +#ifdef _LIBC + /* First make sure the handling of the `__getopt_nonoption_flags' + string can work normally. Our top argument must be in the range + of the string. */ + if (nonoption_flags_len > 0 && top >= nonoption_flags_max_len) + { + /* We must extend the array. The user plays games with us and + presents new arguments. */ + char *new_str = malloc (top + 1); + if (new_str == NULL) + nonoption_flags_len = nonoption_flags_max_len = 0; + else + { + memset (__mempcpy (new_str, __getopt_nonoption_flags, + nonoption_flags_max_len), + '\0', top + 1 - nonoption_flags_max_len); + nonoption_flags_max_len = top + 1; + __getopt_nonoption_flags = new_str; + } + } +#endif + + while (top > middle && middle > bottom) + { + if (top - middle > middle - bottom) + { + /* Bottom segment is the short one. */ + int len = middle - bottom; + register int i; + + /* Swap it with the top part of the top segment. */ + for (i = 0; i < len; i++) + { + tem = argv[bottom + i]; + argv[bottom + i] = argv[top - (middle - bottom) + i]; + argv[top - (middle - bottom) + i] = tem; + SWAP_FLAGS (bottom + i, top - (middle - bottom) + i); + } + /* Exclude the moved bottom segment from further swapping. */ + top -= len; + } + else + { + /* Top segment is the short one. */ + int len = top - middle; + register int i; + + /* Swap it with the bottom part of the bottom segment. */ + for (i = 0; i < len; i++) + { + tem = argv[bottom + i]; + argv[bottom + i] = argv[middle + i]; + argv[middle + i] = tem; + SWAP_FLAGS (bottom + i, middle + i); + } + /* Exclude the moved top segment from further swapping. */ + bottom += len; + } + } + + /* Update records for the slots the non-options now occupy. */ + + first_nonopt += (optind - last_nonopt); + last_nonopt = optind; +} + +/* Initialize the internal data when the first call is made. */ + +#if defined __STDC__ && __STDC__ +static const char *_getopt_initialize (int, char *const *, const char *); +#endif +static const char * +_getopt_initialize (argc, argv, optstring) + int argc; + char *const *argv; + const char *optstring; +{ + /* Start processing options with ARGV-element 1 (since ARGV-element 0 + is the program name); the sequence of previously skipped + non-option ARGV-elements is empty. */ + + first_nonopt = last_nonopt = optind; + + nextchar = NULL; + + posixly_correct = getenv ("POSIXLY_CORRECT"); + + /* Determine how to handle the ordering of options and nonoptions. */ + + if (optstring[0] == '-') + { + ordering = RETURN_IN_ORDER; + ++optstring; + } + else if (optstring[0] == '+') + { + ordering = REQUIRE_ORDER; + ++optstring; + } + else if (posixly_correct != NULL) + ordering = REQUIRE_ORDER; + else + ordering = PERMUTE; + +#ifdef _LIBC + if (posixly_correct == NULL + && argc == original_argc && argv == original_argv) + { + if (nonoption_flags_max_len == 0) + { + if (__getopt_nonoption_flags == NULL + || __getopt_nonoption_flags[0] == '\0') + nonoption_flags_max_len = -1; + else + { + const char *orig_str = __getopt_nonoption_flags; + int len = nonoption_flags_max_len = strlen (orig_str); + if (nonoption_flags_max_len < argc) + nonoption_flags_max_len = argc; + __getopt_nonoption_flags = + (char *) malloc (nonoption_flags_max_len); + if (__getopt_nonoption_flags == NULL) + nonoption_flags_max_len = -1; + else + memset (__mempcpy (__getopt_nonoption_flags, orig_str, len), + '\0', nonoption_flags_max_len - len); + } + } + nonoption_flags_len = nonoption_flags_max_len; + } + else + nonoption_flags_len = 0; +#endif + + return optstring; +} + +/* Scan elements of ARGV (whose length is ARGC) for option characters + given in OPTSTRING. + + If an element of ARGV starts with '-', and is not exactly "-" or "--", + then it is an option element. The characters of this element + (aside from the initial '-') are option characters. If `getopt' + is called repeatedly, it returns successively each of the option characters + from each of the option elements. + + If `getopt' finds another option character, it returns that character, + updating `optind' and `nextchar' so that the next call to `getopt' can + resume the scan with the following option character or ARGV-element. + + If there are no more option characters, `getopt' returns -1. + Then `optind' is the index in ARGV of the first ARGV-element + that is not an option. (The ARGV-elements have been permuted + so that those that are not options now come last.) + + OPTSTRING is a string containing the legitimate option characters. + If an option character is seen that is not listed in OPTSTRING, + return '?' after printing an error message. If you set `opterr' to + zero, the error message is suppressed but we still return '?'. + + If a char in OPTSTRING is followed by a colon, that means it wants an arg, + so the following text in the same ARGV-element, or the text of the following + ARGV-element, is returned in `optarg'. Two colons mean an option that + wants an optional arg; if there is text in the current ARGV-element, + it is returned in `optarg', otherwise `optarg' is set to zero. + + If OPTSTRING starts with `-' or `+', it requests different methods of + handling the non-option ARGV-elements. + See the comments about RETURN_IN_ORDER and REQUIRE_ORDER, above. + + Long-named options begin with `--' instead of `-'. + Their names may be abbreviated as long as the abbreviation is unique + or is an exact match for some defined option. If they have an + argument, it follows the option name in the same ARGV-element, separated + from the option name by a `=', or else the in next ARGV-element. + When `getopt' finds a long-named option, it returns 0 if that option's + `flag' field is nonzero, the value of the option's `val' field + if the `flag' field is zero. + + The elements of ARGV aren't really const, because we permute them. + But we pretend they're const in the prototype to be compatible + with other systems. + + LONGOPTS is a vector of `struct option' terminated by an + element containing a name which is zero. + + LONGIND returns the index in LONGOPT of the long-named option found. + It is only valid when a long-named option has been found by the most + recent call. + + If LONG_ONLY is nonzero, '-' as well as '--' can introduce + long-named options. */ + +int +_getopt_internal (argc, argv, optstring, longopts, longind, long_only) + int argc; + char *const *argv; + const char *optstring; + const struct option *longopts; + int *longind; + int long_only; +{ + int print_errors = opterr; + if (optstring[0] == ':') + print_errors = 0; + + optarg = NULL; + + if (optind == 0 || !__getopt_initialized) + { + if (optind == 0) + optind = 1; /* Don't scan ARGV[0], the program name. */ + optstring = _getopt_initialize (argc, argv, optstring); + __getopt_initialized = 1; + } + + /* Test whether ARGV[optind] points to a non-option argument. + Either it does not have option syntax, or there is an environment flag + from the shell indicating it is not an option. The later information + is only used when the used in the GNU libc. */ +#ifdef _LIBC +# define NONOPTION_P (argv[optind][0] != '-' || argv[optind][1] == '\0' \ + || (optind < nonoption_flags_len \ + && __getopt_nonoption_flags[optind] == '1')) +#else +# define NONOPTION_P (argv[optind][0] != '-' || argv[optind][1] == '\0') +#endif + + if (nextchar == NULL || *nextchar == '\0') + { + /* Advance to the next ARGV-element. */ + + /* Give FIRST_NONOPT & LAST_NONOPT rational values if OPTIND has been + moved back by the user (who may also have changed the arguments). */ + if (last_nonopt > optind) + last_nonopt = optind; + if (first_nonopt > optind) + first_nonopt = optind; + + if (ordering == PERMUTE) + { + /* If we have just processed some options following some non-options, + exchange them so that the options come first. */ + + if (first_nonopt != last_nonopt && last_nonopt != optind) + exchange ((char **) argv); + else if (last_nonopt != optind) + first_nonopt = optind; + + /* Skip any additional non-options + and extend the range of non-options previously skipped. */ + + while (optind < argc && NONOPTION_P) + optind++; + last_nonopt = optind; + } + + /* The special ARGV-element `--' means premature end of options. + Skip it like a null option, + then exchange with previous non-options as if it were an option, + then skip everything else like a non-option. */ + + if (optind != argc && !strcmp (argv[optind], "--")) + { + optind++; + + if (first_nonopt != last_nonopt && last_nonopt != optind) + exchange ((char **) argv); + else if (first_nonopt == last_nonopt) + first_nonopt = optind; + last_nonopt = argc; + + optind = argc; + } + + /* If we have done all the ARGV-elements, stop the scan + and back over any non-options that we skipped and permuted. */ + + if (optind == argc) + { + /* Set the next-arg-index to point at the non-options + that we previously skipped, so the caller will digest them. */ + if (first_nonopt != last_nonopt) + optind = first_nonopt; + return -1; + } + + /* If we have come to a non-option and did not permute it, + either stop the scan or describe it to the caller and pass it by. */ + + if (NONOPTION_P) + { + if (ordering == REQUIRE_ORDER) + return -1; + optarg = argv[optind++]; + return 1; + } + + /* We have found another option-ARGV-element. + Skip the initial punctuation. */ + + nextchar = (argv[optind] + 1 + + (longopts != NULL && argv[optind][1] == '-')); + } + + /* Decode the current option-ARGV-element. */ + + /* Check whether the ARGV-element is a long option. + + If long_only and the ARGV-element has the form "-f", where f is + a valid short option, don't consider it an abbreviated form of + a long option that starts with f. Otherwise there would be no + way to give the -f short option. + + On the other hand, if there's a long option "fubar" and + the ARGV-element is "-fu", do consider that an abbreviation of + the long option, just like "--fu", and not "-f" with arg "u". + + This distinction seems to be the most useful approach. */ + + if (longopts != NULL + && (argv[optind][1] == '-' + || (long_only && (argv[optind][2] || !my_index (optstring, argv[optind][1]))))) + { + char *nameend; + const struct option *p; + const struct option *pfound = NULL; + int exact = 0; + int ambig = 0; + int indfound = -1; + int option_index; + + for (nameend = nextchar; *nameend && *nameend != '='; nameend++) + /* Do nothing. */ ; + + /* Test all long options for either exact match + or abbreviated matches. */ + for (p = longopts, option_index = 0; p->name; p++, option_index++) + if (!strncmp (p->name, nextchar, nameend - nextchar)) + { + if ((unsigned int) (nameend - nextchar) + == (unsigned int) strlen (p->name)) + { + /* Exact match found. */ + pfound = p; + indfound = option_index; + exact = 1; + break; + } + else if (pfound == NULL) + { + /* First nonexact match found. */ + pfound = p; + indfound = option_index; + } + else + /* Second or later nonexact match found. */ + ambig = 1; + } + + if (ambig && !exact) + { + if (print_errors) + fprintf (stderr, _("%s: option `%s' is ambiguous\n"), + argv[0], argv[optind]); + nextchar += strlen (nextchar); + optind++; + optopt = 0; + return '?'; + } + + if (pfound != NULL) + { + option_index = indfound; + optind++; + if (*nameend) + { + /* Don't test has_arg with >, because some C compilers don't + allow it to be used on enums. */ + if (pfound->has_arg) + optarg = nameend + 1; + else + { + if (print_errors) + { + if (argv[optind - 1][1] == '-') + /* --option */ + fprintf (stderr, + _("%s: option `--%s' doesn't allow an argument\n"), + argv[0], pfound->name); + else + /* +option or -option */ + fprintf (stderr, + _("%s: option `%c%s' doesn't allow an argument\n"), + argv[0], argv[optind - 1][0], pfound->name); + } + + nextchar += strlen (nextchar); + + optopt = pfound->val; + return '?'; + } + } + else if (pfound->has_arg == 1) + { + if (optind < argc) + optarg = argv[optind++]; + else + { + if (print_errors) + fprintf (stderr, + _("%s: option `%s' requires an argument\n"), + argv[0], argv[optind - 1]); + nextchar += strlen (nextchar); + optopt = pfound->val; + return optstring[0] == ':' ? ':' : '?'; + } + } + nextchar += strlen (nextchar); + if (longind != NULL) + *longind = option_index; + if (pfound->flag) + { + *(pfound->flag) = pfound->val; + return 0; + } + return pfound->val; + } + + /* Can't find it as a long option. If this is not getopt_long_only, + or the option starts with '--' or is not a valid short + option, then it's an error. + Otherwise interpret it as a short option. */ + if (!long_only || argv[optind][1] == '-' + || my_index (optstring, *nextchar) == NULL) + { + if (print_errors) + { + if (argv[optind][1] == '-') + /* --option */ + fprintf (stderr, _("%s: unrecognized option `--%s'\n"), + argv[0], nextchar); + else + /* +option or -option */ + fprintf (stderr, _("%s: unrecognized option `%c%s'\n"), + argv[0], argv[optind][0], nextchar); + } + nextchar = (char *) ""; + optind++; + optopt = 0; + return '?'; + } + } + + /* Look at and handle the next short option-character. */ + + { + char c = *nextchar++; + char *temp = my_index (optstring, c); + + /* Increment `optind' when we start to process its last character. */ + if (*nextchar == '\0') + ++optind; + + if (temp == NULL || c == ':') + { + if (print_errors) + { + if (posixly_correct) + /* 1003.2 specifies the format of this message. */ + fprintf (stderr, _("%s: illegal option -- %c\n"), + argv[0], c); + else + fprintf (stderr, _("%s: invalid option -- %c\n"), + argv[0], c); + } + optopt = c; + return '?'; + } + /* Convenience. Treat POSIX -W foo same as long option --foo */ + if (temp[0] == 'W' && temp[1] == ';') + { + char *nameend; + const struct option *p; + const struct option *pfound = NULL; + int exact = 0; + int ambig = 0; + int indfound = 0; + int option_index; + + /* This is an option that requires an argument. */ + if (*nextchar != '\0') + { + optarg = nextchar; + /* If we end this ARGV-element by taking the rest as an arg, + we must advance to the next element now. */ + optind++; + } + else if (optind == argc) + { + if (print_errors) + { + /* 1003.2 specifies the format of this message. */ + fprintf (stderr, _("%s: option requires an argument -- %c\n"), + argv[0], c); + } + optopt = c; + if (optstring[0] == ':') + c = ':'; + else + c = '?'; + return c; + } + else + /* We already incremented `optind' once; + increment it again when taking next ARGV-elt as argument. */ + optarg = argv[optind++]; + + /* optarg is now the argument, see if it's in the + table of longopts. */ + + for (nextchar = nameend = optarg; *nameend && *nameend != '='; nameend++) + /* Do nothing. */ ; + + /* Test all long options for either exact match + or abbreviated matches. */ + for (p = longopts, option_index = 0; p->name; p++, option_index++) + if (!strncmp (p->name, nextchar, nameend - nextchar)) + { + if ((unsigned int) (nameend - nextchar) == strlen (p->name)) + { + /* Exact match found. */ + pfound = p; + indfound = option_index; + exact = 1; + break; + } + else if (pfound == NULL) + { + /* First nonexact match found. */ + pfound = p; + indfound = option_index; + } + else + /* Second or later nonexact match found. */ + ambig = 1; + } + if (ambig && !exact) + { + if (print_errors) + fprintf (stderr, _("%s: option `-W %s' is ambiguous\n"), + argv[0], argv[optind]); + nextchar += strlen (nextchar); + optind++; + return '?'; + } + if (pfound != NULL) + { + option_index = indfound; + if (*nameend) + { + /* Don't test has_arg with >, because some C compilers don't + allow it to be used on enums. */ + if (pfound->has_arg) + optarg = nameend + 1; + else + { + if (print_errors) + fprintf (stderr, _("\ +%s: option `-W %s' doesn't allow an argument\n"), + argv[0], pfound->name); + + nextchar += strlen (nextchar); + return '?'; + } + } + else if (pfound->has_arg == 1) + { + if (optind < argc) + optarg = argv[optind++]; + else + { + if (print_errors) + fprintf (stderr, + _("%s: option `%s' requires an argument\n"), + argv[0], argv[optind - 1]); + nextchar += strlen (nextchar); + return optstring[0] == ':' ? ':' : '?'; + } + } + nextchar += strlen (nextchar); + if (longind != NULL) + *longind = option_index; + if (pfound->flag) + { + *(pfound->flag) = pfound->val; + return 0; + } + return pfound->val; + } + nextchar = NULL; + return 'W'; /* Let the application handle it. */ + } + if (temp[1] == ':') + { + if (temp[2] == ':') + { + /* This is an option that accepts an argument optionally. */ + if (*nextchar != '\0') + { + optarg = nextchar; + optind++; + } + else + optarg = NULL; + nextchar = NULL; + } + else + { + /* This is an option that requires an argument. */ + if (*nextchar != '\0') + { + optarg = nextchar; + /* If we end this ARGV-element by taking the rest as an arg, + we must advance to the next element now. */ + optind++; + } + else if (optind == argc) + { + if (print_errors) + { + /* 1003.2 specifies the format of this message. */ + fprintf (stderr, + _("%s: option requires an argument -- %c\n"), + argv[0], c); + } + optopt = c; + if (optstring[0] == ':') + c = ':'; + else + c = '?'; + } + else + /* We already incremented `optind' once; + increment it again when taking next ARGV-elt as argument. */ + optarg = argv[optind++]; + nextchar = NULL; + } + } + return c; + } +} + +int +getopt (argc, argv, optstring) + int argc; + char *const *argv; + const char *optstring; +{ + return _getopt_internal (argc, argv, optstring, + (const struct option *) 0, + (int *) 0, + 0); +} + +#endif /* Not ELIDE_CODE. */ + +#ifdef TEST + +/* Compile with -DTEST to make an executable for use in testing + the above definition of `getopt'. */ + +int +main (argc, argv) + int argc; + char **argv; +{ + int c; + int digit_optind = 0; + + while (1) + { + int this_option_optind = optind ? optind : 1; + + c = getopt (argc, argv, "abc:d:0123456789"); + if (c == -1) + break; + + switch (c) + { + case '0': + case '1': + case '2': + case '3': + case '4': + case '5': + case '6': + case '7': + case '8': + case '9': + if (digit_optind != 0 && digit_optind != this_option_optind) + printf ("digits occur in two different argv-elements.\n"); + digit_optind = this_option_optind; + printf ("option %c\n", c); + break; + + case 'a': + printf ("option a\n"); + break; + + case 'b': + printf ("option b\n"); + break; + + case 'c': + printf ("option c with value `%s'\n", optarg); + break; + + case '?': + break; + + default: + printf ("?? getopt returned character code 0%o ??\n", c); + } + } + + if (optind < argc) + { + printf ("non-option ARGV-elements: "); + while (optind < argc) + printf ("%s ", argv[optind++]); + printf ("\n"); + } + + exit (0); +} + +#endif /* TEST */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.h new file mode 100755 index 00000000..b0147e9d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.h @@ -0,0 +1,169 @@ +/* Declarations for getopt. + Copyright (C) 1989,90,91,92,93,94,96,97,98 Free Software Foundation, Inc. + This file is part of the GNU C Library. + + The GNU C Library is free software; you can redistribute it and/or + modify it under the terms of the GNU Library General Public License as + published by the Free Software Foundation; either version 2 of the + License, or (at your option) any later version. + + The GNU C Library is distributed in the hope that it will be useful, + but WITHOUT ANY WARRANTY; without even the implied warranty of + MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU + Library General Public License for more details. + + You should have received a copy of the GNU Library General Public + License along with the GNU C Library; see the file COPYING.LIB. If not, + write to the Free Software Foundation, Inc., 59 Temple Place - Suite 330, + Boston, MA 02111-1307, USA. */ + +#ifndef _GETOPT_H + +#ifndef __need_getopt +# define _GETOPT_H 1 +#endif + +#ifdef __cplusplus +extern "C" { +#endif + +/* For communication from `getopt' to the caller. + When `getopt' finds an option that takes an argument, + the argument value is returned here. + Also, when `ordering' is RETURN_IN_ORDER, + each non-option ARGV-element is returned here. */ + +extern char *optarg; + +/* Index in ARGV of the next element to be scanned. + This is used for communication to and from the caller + and for communication between successive calls to `getopt'. + + On entry to `getopt', zero means this is the first call; initialize. + + When `getopt' returns -1, this is the index of the first of the + non-option elements that the caller should itself scan. + + Otherwise, `optind' communicates from one call to the next + how much of ARGV has been scanned so far. */ + +extern int optind; + +/* Callers store zero here to inhibit the error message `getopt' prints + for unrecognized options. */ + +extern int opterr; + +/* Set to an option character which was unrecognized. */ + +extern int optopt; + +#ifndef __need_getopt +/* Describe the long-named options requested by the application. + The LONG_OPTIONS argument to getopt_long or getopt_long_only is a vector + of `struct option' terminated by an element containing a name which is + zero. + + The field `has_arg' is: + no_argument (or 0) if the option does not take an argument, + required_argument (or 1) if the option requires an argument, + optional_argument (or 2) if the option takes an optional argument. + + If the field `flag' is not NULL, it points to a variable that is set + to the value given in the field `val' when the option is found, but + left unchanged if the option is not found. + + To have a long-named option do something other than set an `int' to + a compiled-in constant, such as set a value from `optarg', set the + option's `flag' field to zero and its `val' field to a nonzero + value (the equivalent single-letter option character, if there is + one). For long options that have a zero `flag' field, `getopt' + returns the contents of the `val' field. */ + +struct option +{ +# if defined __STDC__ && __STDC__ + const char *name; +# else + char *name; +# endif + /* has_arg can't be an enum because some compilers complain about + type mismatches in all the code that assumes it is an int. */ + int has_arg; + int *flag; + int val; +}; + +/* Names for the values of the `has_arg' field of `struct option'. */ + +# define no_argument 0 +# define required_argument 1 +# define optional_argument 2 +#endif /* need getopt */ + + +/* Get definitions and prototypes for functions to process the + arguments in ARGV (ARGC of them, minus the program name) for + options given in OPTS. + + Return the option character from OPTS just read. Return -1 when + there are no more options. For unrecognized options, or options + missing arguments, `optopt' is set to the option letter, and '?' is + returned. + + The OPTS string is a list of characters which are recognized option + letters, optionally followed by colons, specifying that that letter + takes an argument, to be placed in `optarg'. + + If a letter in OPTS is followed by two colons, its argument is + optional. This behavior is specific to the GNU `getopt'. + + The argument `--' causes premature termination of argument + scanning, explicitly telling `getopt' that there are no more + options. + + If OPTS begins with `--', then non-option arguments are treated as + arguments to the option '\0'. This behavior is specific to the GNU + `getopt'. */ + +#if defined __STDC__ && __STDC__ +# ifdef __GNU_LIBRARY__ +/* Many other libraries have conflicting prototypes for getopt, with + differences in the consts, in stdlib.h. To avoid compilation + errors, only prototype getopt for the GNU C library. */ +extern int getopt (int __argc, char *const *__argv, const char *__shortopts); +# else /* not __GNU_LIBRARY__ */ +extern int getopt (); +# endif /* __GNU_LIBRARY__ */ + +# ifndef __need_getopt +extern int getopt_long (int __argc, char *const *__argv, const char *__shortopts, + const struct option *__longopts, int *__longind); +extern int getopt_long_only (int __argc, char *const *__argv, + const char *__shortopts, + const struct option *__longopts, int *__longind); + +/* Internal only. Users should not call this directly. */ +extern int _getopt_internal (int __argc, char *const *__argv, + const char *__shortopts, + const struct option *__longopts, int *__longind, + int __long_only); +# endif +#else /* not __STDC__ */ +extern int getopt (); +# ifndef __need_getopt +extern int getopt_long (); +extern int getopt_long_only (); + +extern int _getopt_internal (); +# endif +#endif /* __STDC__ */ + +#ifdef __cplusplus +} +#endif + +/* Make sure we later can get all the definitions and declarations. */ +#undef __need_getopt + +#endif /* getopt.h */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt.o new file mode 100755 index 0000000000000000000000000000000000000000..db55539aaf6598f0a3e07a9b3e6f9194ba9bfd98 GIT binary patch literal 2892 zcma)8O^g&(5U$tLGjDcgcUTxi5Q$3`borZMVY6<4EI$jZt1B3P&=BL;Gt;v>+1c)4 zx@QqCMl{A~0>r=tJSYeCVuUCrp7dbi!9;Iz(sG$ z17*q@XRwlqx)+k2v|MKCq;(6R?Jw9falwbj8NS&``zACOPe2pJPTJ=|YOGhO)Cebj zpZO(K(3ha^Q^x_rq}QO}oO;7hTORq?=6`U6;330=+YWSSSc zR^Nhkwb1+ZR#@*5I;7Dh>t3Oo^gcMR6*{8Xm#lR{x9e|VU9aXbXLzUn8gzs53?0)s z-~+Ov3H`893*D#B!g;f*BI57?Z5Fyk?KbqVejV1W>Y$-V^&h}(Dl{RcbpTpauNnG? zz76LIwPc)U^(^S5LUXO*r}f8B?-%-<{u$PTQpWT86zG(C(>T9KX}fPb#E()~)JdM& zZ+((kfYYbZGAZ*e0^W>PX=kp2eI9LFnv(V?&r8~uS(`D2&dG*S0EQ6Lgw7i6Huu;xeVXUbE%5$pjE7Ul}5YjQZFf%>mm0h2&;9!FptN! zQ7^}0c&6zFtmQ;hnmJwyoF%v9dR0SCx9Z{Dtn37?F_zmk;~32Qt#AlOAM;zTQ#I+i*At% z4c*{uaoY9jZt+mvE1sykp65Jy>|j^gFLy1F_{8}w=S-BKC<%SzmQ~k04XmhkP&9KE?;CbU?C7uWg$QjVZ zsNvi;_Qz&LbuIdQJUTlS>Eg`s{zuwcz2SO(*B9C5+|X}^g^JN)?~u=I(JrFtsi{3f zBizj`(o8A@XBK%ijA1Ln`B)0kfI`&?9V(QAfJL|5o+~-!a?4$!Ld$K41`Up_jk@Q? zG6$l9=Z9{AGwujNZax(%{^Fv`2kHL~yd(L6Ao+Yz^!@72wnf}1ehK0K=JycW(|rAx z-*$;7;Y{9ZG3l{Q_Q)`Q&(}>nt1?hK#vZ=*RfxJ@;zp&r_yYj;B@MYfr;Z6Z}?*4?+=5?6u;}z`7Nev|4a2kV9?| z+$i{<;0{5YY546GJR~?H_^jXyg80pWe^c#8u3EmL=Qt&&$9|eCG{7W#) zn}Iy{32qUb5S$h~A?ON*g0Bj`E%=@wo)5&u4;m2vEx;cHe-peTnBktnzD{tP;JDzV O;H= +#endif + +#include "getopt.h" + +#if !defined __STDC__ || !__STDC__ +/* This is a separate conditional since some stdc systems + reject `defined (const)'. */ +#ifndef const +#define const +#endif +#endif + +#include + +/* Comment out all this code if we are using the GNU C Library, and are not + actually compiling the library itself. This code is part of the GNU C + Library, but also included in many other GNU distributions. Compiling + and linking in this code is a waste when using the GNU C library + (especially if it is a shared library). Rather than having every GNU + program understand `configure --with-gnu-libc' and omit the object files, + it is simpler to just do this in the source for each such file. */ + +#define GETOPT_INTERFACE_VERSION 2 +#if !defined _LIBC && defined __GLIBC__ && __GLIBC__ >= 2 +#include +#if _GNU_GETOPT_INTERFACE_VERSION == GETOPT_INTERFACE_VERSION +#define ELIDE_CODE +#endif +#endif + +#ifndef ELIDE_CODE + + +/* This needs to come after some library #include + to get __GNU_LIBRARY__ defined. */ +#ifdef __GNU_LIBRARY__ +#include +#endif + +#ifndef NULL +#define NULL 0 +#endif + +int +getopt_long (argc, argv, options, long_options, opt_index) + int argc; + char *const *argv; + const char *options; + const struct option *long_options; + int *opt_index; +{ + return _getopt_internal (argc, argv, options, long_options, opt_index, 0); +} + +/* Like getopt_long, but '-' as well as '--' can indicate a long option. + If an option that starts with '-' (not '--') doesn't match a long option, + but does match a short option, it is parsed as a short option + instead. */ + +int +getopt_long_only (argc, argv, options, long_options, opt_index) + int argc; + char *const *argv; + const char *options; + const struct option *long_options; + int *opt_index; +{ + return _getopt_internal (argc, argv, options, long_options, opt_index, 1); +} + + +#endif /* Not ELIDE_CODE. */ + +#ifdef TEST + +#include + +int +main (argc, argv) + int argc; + char **argv; +{ + int c; + int digit_optind = 0; + + while (1) + { + int this_option_optind = optind ? optind : 1; + int option_index = 0; + static struct option long_options[] = + { + {"add", 1, 0, 0}, + {"append", 0, 0, 0}, + {"delete", 1, 0, 0}, + {"verbose", 0, 0, 0}, + {"create", 0, 0, 0}, + {"file", 1, 0, 0}, + {0, 0, 0, 0} + }; + + c = getopt_long (argc, argv, "abc:d:0123456789", + long_options, &option_index); + if (c == -1) + break; + + switch (c) + { + case 0: + printf ("option %s", long_options[option_index].name); + if (optarg) + printf (" with arg %s", optarg); + printf ("\n"); + break; + + case '0': + case '1': + case '2': + case '3': + case '4': + case '5': + case '6': + case '7': + case '8': + case '9': + if (digit_optind != 0 && digit_optind != this_option_optind) + printf ("digits occur in two different argv-elements.\n"); + digit_optind = this_option_optind; + printf ("option %c\n", c); + break; + + case 'a': + printf ("option a\n"); + break; + + case 'b': + printf ("option b\n"); + break; + + case 'c': + printf ("option c with value `%s'\n", optarg); + break; + + case 'd': + printf ("option d with value `%s'\n", optarg); + break; + + case '?': + break; + + default: + printf ("?? getopt returned character code 0%o ??\n", c); + } + } + + if (optind < argc) + { + printf ("non-option ARGV-elements: "); + while (optind < argc) + printf ("%s ", argv[optind++]); + printf ("\n"); + } + + exit (0); +} + +#endif /* TEST */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/getopt1.o 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"utils.h" +#include "globals.h" + +/* forward declarations privat functions */ +static void ini_globs(void); +static void ini_gtoggles (void); +static void ini_gvars(void); +static void ini_garrays (void); +static void usage(int status); +static void display_settings(void); +static void display_fileformat(void); +static char *verbose(int optval, const char *which); +static int process_options (int argc, char *argv[]); + +static char UNUSED rcsid[] ="$Id: globals.c,v 1.5 2005/02/18 13:29:04 ivo Exp $"; +#define MAXMSG 8 +static char msg[MAXMSG][60] = +{{"off"}, + {"on"}, + {"current time"}, + {"take from input file"}, + {"open chain"}, + {"mfe structure of sequence"}, + {"ViennaRNA-Package-1.4 defaults"}, + {""} +}; + +static struct option const long_options[] = +{ {"dangle", required_argument, 0, 0}, + {"Temp", required_argument, 0, 0}, + {"Par", required_argument, 0, 0}, + {"logML", no_argument, >V.logML, 0}, + {"noShift", no_argument, >V.noShift, 1}, + {"noLP", no_argument, >V.noLP, 1}, + {"seed", required_argument, 0, 0}, + {"time", required_argument, 0, 0}, + {"num", required_argument, 0, 0}, + {"start", no_argument, >V.start, 1}, + {"stop", no_argument, >V.stop, 1}, + {"fpt", no_argument, >V.fpt, 0}, + {"met", no_argument, >V.mc, 1}, + {"grow", required_argument, 0, 0}, + {"glen", required_argument, 0, 0}, + {"log", required_argument, 0, 0}, + {"silent", no_argument, 0, 0}, + {"lmin", no_argument, >V.lmin, 1}, + {"cut", required_argument, 0, 0}, + {"help", no_argument, 0, 'h'}, + {"verbose", no_argument, 0, 0}, + {NULL, 0, NULL, 0} +}; + +/**/ +void decode_switches(int argc, char *argv[]) { + ini_globs(); + strcpy(GAV.ProgramName, argv[0]); + process_options(argc, argv); +} + +/**/ +void clean_up_globals(void) { + int i; + free(GAV.ProgramName); + free(GAV.ParamFile); + free(GAV.BaseName); + free(GAV.farbe); + free(GAV.farbe_full); + free(GAV.startform); + free(GAV.currform); + free(GAV.prevform); + for (i = 0; i < GSV.maxS; i++) free(GAV.stopform[i]); + free(GAV.stopform); + free(GAV.sE); +} + +/**/ +static void usage(int status) { + fprintf(stderr, "\n%s - Kinetic Folding Program for Nucleic Acids -\n", + GAV.ProgramName); + fprintf(stderr, "Usage: %s [OPTION] < FILE\n", GAV.ProgramName); + fprintf(stderr, + "Options:\n" + " EnergyModel\n" + " --dangle <0|1|2> set dangling end model to (non|normal|double)\n" + " --Temp set simulation temperature to \n" + " --Par use energy-parameter-file \n" + " --logML use linear multiloop-function not logarithmic\n" + " MoveSet\n" + " --noShift turn off shift-moves\n" + " --noLP forbit structures with isolated base-pairs\n" + " Simulation\n" + " --seed set random seed to \n" + " --time set maxtime of simulation to \n" + " --num set number of simulations to \n" + " --start set start structure\n" + " --stop set stop structure(s)\n" + " --met use Metropolis rule not Kawasaki rule\n" + " --fpt stop stop structure(s) is reached\n" + " --grow grow chain every time steps\n" + " Output\n" + " --log set basename of log-file to \n" + " --err set basename of error-log-file to \n" + " --silent no output to stdout\n" + " --verbose more information to stdout\n" + " --lmin output only local minima to stdout\n" + " --cut output structures with E <= to stdout\n"); + display_settings(); + display_fileformat(); + exit (status); +} + +/**/ +static void display_fileformat(void) { + fprintf(stderr, + "Input File Format:\n" + "1st line sequence\n" + "2nd line start structure (if option --start is used)\n" + "following lines stop structures\n\n"); +} + +/**/ +void log_prog_params(FILE *FP) { + fprintf( FP, + "#<\n#Date: %s" + "#EnergyModel: dangle=%d Temp=%.1f logML=%s Par=%s\n" + "#MoveSet: noShift=%s noLP=%s\n" + "#Simulation: num=%d time=%.2f seed=%s fpt=%s mc=%s\n" + "#Output: log=%s silent=%s lmin=%s cut=%.2f\n", + time_stamp(), + GTV.dangle, + GSV.Temp, + verbose(GTV.logML, "logML"), + GAV.ParamFile, + verbose(GTV.noShift, NULL), + verbose(GTV.noLP, NULL), + GSV.num, + GSV.time, + verbose(GTV.seed, "seed"), + verbose(GTV.fpt, NULL), + verbose(GTV.mc, "met"), + GAV.BaseName, + verbose(GTV.silent, NULL), + verbose(GTV.lmin, NULL), + GSV.cut); + fflush(FP); +} + +/**/ +void log_start_stop(FILE *FP) { + int i; + fprintf(FP, "#%s\n#%s (%6.2f)\n", GAV.farbe, GAV.startform, GSV.startE); + for (i = 0; i < GSV.maxS; i++) { + fprintf(FP, "#%s (%6.2f) X%02d\n", GAV.stopform[i], GAV.sE[i], i+1); + } + fprintf(FP, "(%-5hu %5hu %5hu)", GAV.subi[0], GAV.subi[1], GAV.subi[2]); + fflush(FP); +} + +/**/ +static void display_settings(void) { + fprintf(stderr, + "Default Settings:\n" + " EnergyModel\n" + " --dangle = %d\n" + " --Temp = %.2f\n" + " --Par = %s\n" + " --logML = %s\n" + " MoveSet\n" + " --noShift = %s\n" + " --noLP = %s\n" + " Simulation\n" + " --seed = %s\n" + " --time = %.1f\n" + " --num = %d\n" + " --start = %s\n" + " --stop = %s\n" + " --met = %s\n" + " --fpt = %s\n" + " Output\n" + " --log = %s\n" + " --silent = %s\n" + " --verbose = %s\n" + " --lmin = %s\n" + " --cut = %.2f\n", + GTV.dangle, + GSV.Temp, + GAV.ParamFile, + verbose(GTV.logML, "logML"), + verbose(GTV.noShift, NULL), + verbose(GTV.noLP, NULL), + verbose(GTV.seed, "seed"), + GSV.time, + GSV.num, + verbose(GTV.start, "start"), + verbose(GTV.stop, "stop"), + verbose(GTV.mc, "met"), + verbose(GTV.fpt, NULL), + GAV.BaseName, + verbose(GTV.silent, NULL), + verbose(GTV.verbose, NULL), + verbose(GTV.lmin, NULL), + GSV.cut); +} + +/**/ +static char *verbose (int optval, const char *which) { + if (which == NULL) return msg[optval]; + else { + if ( strcmp(which, "seed") == 0 ) { + if (optval == 0 ) return "clock"; + else { + sprintf(msg[MAXMSG - 1], + "%hu %hu %hu", GAV.subi[0], GAV.subi[1],GAV.subi[2]); + return msg[MAXMSG - 1]; + } + } + + if ( strcmp(which, "met") == 0 ) { + if ( optval == 0 ) return "Kawasaki"; + else return "Metropolis"; + } + + if ( strcmp(which, "logML") == 0 ) { + if ( optval == 0 ) return "linear"; + else return "logarithmic"; + } + + if ( strcmp(which, "start") == 0 ) { + if ( optval == 0 ) return "OpenChain"; + else return "input file"; + } + + if ( strcmp(which, "stop") == 0 ) { + if ( optval == 0 ) return "Mfe"; + else return "input file"; + } + } + return "hae?"; +} + +/**/ +static void ini_globs (void) { + ini_gtoggles(); + ini_gvars(); + ini_garrays(); +} + +/**/ +static int process_options (int argc, char *argv[]) { + int c, itmp; + float ftmp; + double dtmp; + int option_index = 0; + while ((c = getopt_long (argc, argv, "h", + long_options, &option_index)) != EOF) { + switch (c) { + case 0: + if (strcmp(long_options[option_index].name,"dangle")==0) { + itmp = -1; + if (sscanf(optarg, "%d", &itmp) == 0) + usage(EXIT_FAILURE); + else if (itmp == 0 || itmp == 1 || itmp == 2 || itmp == 3) + GTV.dangle = itmp; + else { + fprintf(stderr, "Value of --dangle must be 0|1|2 >%d<\n", itmp); + usage (EXIT_FAILURE); + } + } + + if (strcmp(long_options[option_index].name,"Temp")==0) { + ftmp = -1.0; + if (sscanf(optarg, "%f", &ftmp) == 0) + usage(EXIT_FAILURE); + else if ( ftmp >= 0 ) + GSV.Temp = ftmp; + else { + fprintf(stderr, "Value of --Temp must be >= 0 >%.2f<\n", ftmp); + usage (EXIT_FAILURE); + } + } + + if (strcmp(long_options[option_index].name,"Par")==0) { + if (sscanf(optarg, "%s", GAV.ParamFile) == 0) + usage(EXIT_FAILURE); + else { + GTV.Par = 1; + } + } + + if (strcmp(long_options[option_index].name,"silent")==0) { + GTV.silent = 1; + GTV.verbose = 0; + } + + if (strcmp(long_options[option_index].name,"verbose")==0) { + if (GTV.silent == 0) + GTV.verbose = 1; + } + + if (strcmp(long_options[option_index].name,"seed")==0) { + if (sscanf(optarg, "%hu=%hu=%hu", + &GAV.subi[0], &GAV.subi[1], &GAV.subi[2]) == 0) + usage(EXIT_FAILURE); + else GTV.seed = 1; + } + + if (strcmp(long_options[option_index].name,"time")==0) { + dtmp = -1.0; + if (sscanf(optarg, "%lf", &dtmp) == 0) + usage(EXIT_FAILURE); + else if ( dtmp > 0 ) + GSV.time = dtmp; + else { + fprintf(stderr, "Value of --time must be > 0 >%lf<\n", dtmp); + usage(EXIT_FAILURE); + } + } + + if (strcmp(long_options[option_index].name,"num")==0) { + itmp = -1; + if (sscanf(optarg, "%d", &itmp) == 0) + usage(EXIT_FAILURE); + else if ( itmp > 0 ) + GSV.num = itmp; + else { + fprintf(stderr, "Value of --num must be > 0 >%d<\n", itmp); + usage(EXIT_FAILURE); + } + } + + if (strcmp(long_options[option_index].name,"log")==0) + if (sscanf(optarg, "%s", GAV.BaseName) == 0) + usage(EXIT_FAILURE); + + if (strcmp(long_options[option_index].name,"cut")==0) + if (sscanf(optarg, "%f", &GSV.cut) == 0) + usage(EXIT_FAILURE); + + if (strcmp(long_options[option_index].name,"grow")==0) + if (sscanf(optarg, "%lf", &GSV.grow) == 0) + usage(EXIT_FAILURE); + + if (strcmp(long_options[option_index].name,"glen")==0) + if (sscanf(optarg, "%d", &GSV.glen) == 0) + usage(EXIT_FAILURE); + + break; + + case 'h': + usage (0); + default: + usage (EXIT_FAILURE); + } + } + return optind; +} + +/**/ +static void ini_gtoggles(void) { + GTV.Par = 0; + GTV.seed = 0; + GTV.dangle = 2; + GTV.logML = 1; + GTV.noLP = 0; + GTV.noShift = 0; + GTV.start = 0; + GTV.stop = 0; + GTV.silent = 0; + GTV.verbose = 0; + GTV.lmin = 0; + GTV.fpt = 1; + GTV.mc = 0; +} + +/**/ +static void ini_gvars(void) { + GSV.len = 0; + GSV.num = 1; + GSV.maxS = 99; + GSV.cut = 20; + GSV.Temp = 37.0; + GSV.startE = 0.0; + GSV.stopE = 0.0; + GSV.currE = 0.0; + GSV.time = 500.0; + GSV.simTime = 0.0; + GSV.glen = 15; +} + +/**/ +static void ini_garrays(void) { + GAV.ProgramName = (char *)calloc((size_t)256, sizeof(char)); + assert(GAV.ProgramName != NULL); + GAV.ParamFile = (char *)calloc((size_t)256, sizeof(char)); + assert(GAV.ParamFile != NULL); + strcpy(GAV.ParamFile,"VRNA-1.4"); + GAV.BaseName = (char *)calloc((size_t)256, sizeof(char)); + assert(GAV.BaseName != NULL); + strcpy(GAV.BaseName, "kinout"); + GAV.stopform = (char **)calloc(GSV.maxS + 1, sizeof(char *)); + assert(GAV.stopform != NULL); + GAV.farbe = NULL; + GAV.startform = NULL; + GAV.currform = NULL; + GAV.prevform = NULL; +} + +/* End of file */ + + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/globals.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/globals.h new file mode 100755 index 00000000..a58c0f3c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/globals.h @@ -0,0 +1,76 @@ +/* + Last changed Time-stamp: <2005-02-16 13:16:43 ivo> + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: globals.h,v 1.2 2005/02/16 17:00:48 ivo Exp $ +*/ + +#ifndef GLOBDEFS_H +#define GLOBDEFS_H + +#ifdef __GNUC__ +#define UNUSED __attribute__ ((unused)) +#else +#define UNUSED +#endif + +typedef struct _GlobVars { + int len; + int num; + int maxS; + int steps; + float cut; + float Temp; + float startE; + float stopE; + float currE; + double grow; + int glen; + double time; + double simTime; +} GlobVars; + +typedef struct _GlobArrays { + char *ParamFile; + char *ProgramName; + char *BaseName; /* output file basename */ + char *farbe; /* sequence */ + char *farbe_full; /* full sequence (for chain growth simulation) */ + char *startform; /* start structure */ + char **stopform; /* stop structure(s) */ + char *currform; /* current structure */ + char *prevform; /* current structure of previous time step */ + float *sE; /* energy(s) of stop structure(s) */ + unsigned short subi[3]; /* seeds for random-number-generator */ +} GlobArrays; + +typedef struct _GlobToogles { + int Par; + int seed; + int dangle; + int logML; + int noLP; + int noShift; + int start; + int stop; + int silent; + int lmin; + int fpt; + int mc; + int verbose; +} GlobToggles; + +void decode_switches(int argc, char *argv[]); +void clean_up_globals(void); +void log_prog_params(FILE *FP); +void log_start_stop(FILE *FP); + +GlobVars GSV; +GlobArrays GAV; +GlobToggles GTV; + +#endif + + +/* End of file */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/globals.o 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+#include "fold.h" +#include "baum.h" +#include "nachbar.h" +#include "cache_util.h" +#include "utils.h" +#include "globals.h" + +static char UNUSED rcsid[] ="$Id: main.c,v 1.3 2005/02/18 13:29:04 ivo Exp $"; +extern void read_parameter_file(const char fname[]); +extern void get_from_cache(cache_entry *c); + +/* PRIVAT FUNCTIONS */ +static void ini_energy_model(void); +static void read_data(void); +static char *getline(FILE *fp); +static void clean_up(void); + +/**/ +int main(int argc, char *argv[]) { + int i; + char * start; + + /* + process command-line optiones + */ + decode_switches(argc, argv); + + /* + initialize energy parameters + */ + ini_energy_model(); + + /* + read input file + */ + read_data(); + + /* + perform GSV.num simulations + */ + + start = strdup(GAV.startform); /* remember startform for next run */ + for (i = 0; i < GSV.num; i++) { + + /* + initialize or reset ringlist to start conditions + */ + if (GSV.grow>0) { + if (strlen(GAV.farbe)>GSV.glen) { + start[GSV.glen] = '\0'; + GAV.farbe[GSV.glen] = '\0'; + strcpy(GAV.startform,start); + strcpy(GAV.currform,start); + GSV.len=GSV.glen; + } + clean_up_rl(); + } + ini_or_reset_rl(); + + /* + perform simulation + */ + for (GSV.steps = 1;; GSV.steps++) { + cache_entry *c; + + /* + take neighbourhood of current structure from cache if there + else generate it from scratch + */ + if ( (c = lookup_cache(GAV.currform)) ) get_from_cache(c); + else move_it(); + + /* + select a structure from neighbourhood of current structure + and make it to the new current structure. + stop simulation if stop condition is met. + */ + if ( sel_nb() > 0 ) break; + + /* if (GSV.grow>0) grow_chain(); */ + } + } + + /* + clean up memory + */ + free(start); + clean_up(); + return(0); +} + +/**/ +static void ini_energy_model(void) { + if ( !GTV.seed ) { + init_rand(); + GAV.subi[0] = xsubi[0]; + GAV.subi[1] = xsubi[1]; + GAV.subi[2] = xsubi[2]; + } + else { + xsubi[0] = GAV.subi[0]; + xsubi[1] = GAV.subi[1]; + xsubi[2] = GAV.subi[2]; + } + logML = GTV.logML; + dangles = GTV.dangle; + temperature = GSV.Temp; + if( GTV.Par ) read_parameter_file(GAV.ParamFile); + update_fold_params(); +} + +/**/ +static void read_data(void) { + char *ctmp, **s; + int i, len; + + /* + read sequence + */ + ctmp = getline(stdin); + len = strlen(ctmp); + GAV.farbe = (char *)calloc(len+1, sizeof(char)); + assert(GAV.farbe != NULL); + sscanf(ctmp, "%s", GAV.farbe); + GSV.len = strlen(GAV.farbe); + for (i = 0; i < len; i++) GAV.farbe[i] = toupper(GAV.farbe[i]); + free (ctmp); + /* allocate some global arrays */ + GAV.currform = (char *)calloc(GSV.len +1, sizeof(char)); + assert(GAV.currform != NULL); + GAV.prevform = (char *)calloc(GSV.len +1, sizeof(char)); + assert(GAV.prevform != NULL); + GAV.startform = (char *)calloc(GSV.len +1, sizeof(char)); + assert(GAV.startform != NULL); + + /* + read start structure + */ + if (GTV.start) { + ctmp = getline(stdin); + len = strlen(ctmp); + sscanf(ctmp, "%s", GAV.startform); + + if (strlen(GAV.startform) != GSV.len) { + fprintf(stderr, + "read_data():\n%s\n%s\n unequal length!\n", + GAV.farbe, GAV.startform); + exit(1); + } + free (ctmp); + } + else { /* start structure is open chain */ + for (i = 0; i< GSV.len; i++) GAV.startform[i] = '.'; + } + + /* + read stop structure(s) + */ + if (GTV.stop) { + s = GAV.stopform; + while (( ctmp = getline(stdin))) { + *s = (char *)calloc(GSV.len+1, sizeof(char)); + sscanf(ctmp, "%s", *s); + + if ( (s-GAV.stopform) >= GSV.maxS ) { + fprintf(stderr, + "WARNING: Can handle a maximum of %d stop structures\n", + GSV.maxS ); + break; + } + + if (strlen(*s) != GSV.len) { + fprintf(stderr, "read_data():\n%s\n%s\n unequal length!\n", + GAV.farbe, *s); + exit(1); + } + + s++; + free (ctmp); + } + GSV.maxS = (s-GAV.stopform); + } + else { + GSV.maxS = 1; + GAV.stopform[0] = (char *)calloc(GSV.len+1, sizeof(char)); + } + + GAV.farbe_full = strdup(GAV.farbe); + + GAV.sE = (float *)calloc(GSV.maxS, sizeof(float)); +} + +/**/ +static char *getline(FILE *fp) { + char s[512], *line, *cp; + + line = NULL; + do { + if (fgets(s, 512, fp) == NULL) break; + cp = strchr(s, '\n'); + if (cp != NULL) *cp = '\0'; + if (line == NULL) { + line = (char *)calloc((strlen(s) + 1), sizeof(char)); + assert(line != NULL); + } + else + line = (char *)realloc(line, strlen(s) + strlen(line) + 1); + strcat(line, s); + } while(cp == NULL); + return(line); +} + +/**/ +void clean_up(void) { + clean_up_globals(); + clean_up_rl(); + clean_up_nbList(); + kill_cache(); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/main.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/main.o new file mode 100755 index 0000000000000000000000000000000000000000..48988d33bb347db2b4b17dca4e5bdcd7ced4ac56 GIT binary patch literal 11520 zcmb7K3v^snx!z~aBs1wule9_O^gT_|HfhsI(uR_T(sx>N4W*JaDcCYjCTEh7$xN6> zYys&b4G=Y-iSCegnIaN#yq9e(7DljS+D5u^)MVhH~RghKs90xKIR_1W9|cIx;DA!u{F8qy9(>F-+)$~Wv3(D|XjVU_8-{Rni)k<-o1db@4#1HOp}8gm 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zzAc!~eFXJN1ACh1m6&RM{o+)G5pOItP<4w z66EWIb3dZpm4bXb#PqpC6T`+I7Y-e)$0}hH*#IUzFDx92>BI)*9aaG{f&Zm34T`a zK_Xu8o)!MQ;OipiT4g(Vf<7YJDHB{I*dn+~FeUg2!LJB@OYpeh4+WnUd|B{Mg6{~< yMBll;RS~hjH4*VVy^P3y3%< + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: nachbar.c,v 1.6 2006/01/16 10:38:11 ivo Exp $ +*/ + +#include +#include +#include +#include +#include +#include +#include +#include "globals.h" +#include "assert.h" +#include "fold_vars.h" +#include "energy_const.h" +#include "utils.h" +#include "cache_util.h" +#include "baum.h" + +static char UNUSED rcsid[]="$Id: nachbar.c,v 1.6 2006/01/16 10:38:11 ivo Exp $"; + +/* arrays */ +static short *neighbor_list=NULL; +static float *bmf; /* boltzmann weight of structure */ + +/* variables */ +/* static double highestE = -1000.0; */ +/* static double OhighestE = -1000.0; */ +/* static char *highestS, *OhighestS; */ +static int lmin = 1; +static int top = 0; +static int is_from_cache = 0; +/* static double meanE = 0.0; */ +static double totalflux = 0.0; +static double Zeit = 0.0; +static double zeitInc = 0.0; +static double _RT = 0.6; + +/* public functiones */ +void ini_nbList(int chords); +void update_nbList(int i, int j, int iE); +int sel_nb(void); +void clean_up_nbList(void); +extern void update_tree(int i, int j); + +/* privat functiones */ +static void reset_nbList(void); +static void grow_chain(void); +static FILE *logFP=NULL; + +/**/ +void ini_nbList(int chords) { + char logFN[256]; + + _RT = (((temperature + K0) * GASCONST) / 1000.0); + if (neighbor_list!=NULL) return; + /* + list for move coding + make room for 2*chords neighbors (safe bet) + */ + if (chords == 0) chords = 1; + neighbor_list = (short *)calloc(4*chords, sizeof(short)); + assert(neighbor_list != NULL); + /* + list for Boltzmann-factors + */ + bmf = (float *)calloc(2*chords, sizeof(double)); + assert(bmf != NULL); + + /* open log-file */ + logFP = fopen(strcat(strcpy(logFN, GAV.BaseName), ".log"), "a+"); + assert(logFP != NULL); + + /* log initial condition */ + log_prog_params(logFP); + log_start_stop(logFP); +} + +/**/ +void update_nbList(int i, int j, int iE) { + double E, dE, p; + + E = (double)iE/100.; + neighbor_list[2*top] = (short )i; + neighbor_list[2*top+1] = (short )j; + + /* compute rates and some statistics */ + /* meanE += E; */ + dE = E-GSV.currE; + if( GTV.mc ) { + /* metropolis rule */ + if (dE < 0) p = 1; + else p = exp(-(dE / _RT)); + } + else /* kawasaki rule */ + p = exp(-0.5 * (dE / _RT)); + + totalflux += p; + bmf[top++] = (float )p; + if (dE < 0) lmin = 0; + if ((dE == 0) && (lmin==1)) lmin = 2; +} + +/**/ +void get_from_cache(cache_entry *c) { + top = c->top; + totalflux = c->flux; + GSV.currE = c->energy; + lmin = c->lmin; + memcpy(neighbor_list, c->neighbors, 2*top*sizeof(short)); + memcpy(bmf, c->rates, top*sizeof(float)); + is_from_cache = 1; +} + +/**/ +void put_in_cache(void) { + cache_entry *c; + + if ((c = (cache_entry *) malloc(sizeof(cache_entry)))==NULL) { + fprintf(stderr, "out of memory\n"); exit(255); + } +/* c->structure = strdup(GAV.currform); */ + c->structure = (char *) calloc(GSV.len+1, sizeof(char)); + strcpy(c->structure, GAV.currform); + c->neighbors = (short *) malloc(top*2*sizeof(short)); + memcpy(c->neighbors,neighbor_list,top*2*sizeof(short)); + c->rates = (float *) malloc(top*sizeof(float)); + memcpy(c->rates, bmf, top*sizeof(float)); + c->top = top; + c->lmin = lmin; + c->flux = totalflux; + c->energy = GSV.currE; + write_cache(c); +} + +/*============*/ + +int sel_nb(void) { + + char trans, **s; + int next; + double pegel = 0.0, schwelle = 0.0, zufall = 0.0; + int found_stop=0; + + /* before we select a move, store current conformation in cache */ + /* ... unless it just came from there */ + if ( !is_from_cache ) put_in_cache(); + is_from_cache = 0; + + /* draw 2 different a random number */ + schwelle = urn(); + while ( zufall==0 ) zufall = urn(); + + /* advance internal clock */ + if (totalflux>0) + zeitInc = (log(1. / zufall) / totalflux); + else { + if (GSV.grow>0) zeitInc=GSV.grow; + else zeitInc = GSV.time; + } + + Zeit += zeitInc; + if (GSV.grow>0 && GSV.len < strlen(GAV.farbe_full)) grow_chain(); + + /* meanE /= (double)top; */ + + /* normalize boltzmann weights */ + schwelle *=totalflux; + + /* and choose a neighbour structure next */ + for (next = 0; next < top; next++) { + pegel += bmf[next]; + if (pegel > schwelle) break; + } + + /* in case of rounding errors */ + if (next==top) next=top-1; + + /* + process termination contitiones + */ + /* is current structure identical to a stop structure ?*/ + for (found_stop = 0, s = GAV.stopform; *s; s++) { + if (strcmp(*s, GAV.currform) == 0) { + found_stop = (s - GAV.stopform) + 1; + break; + } + } + + if ( ((found_stop > 0) && (GTV.fpt == 1)) || (Zeit > GSV.time) ) { + /* met condition to stop simulation */ + + /* this gose to stdout */ + if ( !GTV.silent ) { + printf("%s %6.2f %10.3f", GAV.currform, GSV.currE, Zeit); + if ( GTV.verbose ) printf("%4d _ %d", top, lmin); + if (found_stop) printf(" X%d\n", found_stop);/* found a stop structure */ + else printf(" O\n"); /* time for simulation is exceeded */ + fflush(stdout); + } + + /* this goes to log */ + /* comment log steps of simulation as well !!! %6.2f round */ + if ( found_stop ) fprintf(logFP," X%02d %12.3f\n", found_stop, Zeit); + else fprintf(logFP," O %12.3f %d %s\n", Zeit, lmin, GAV.currform); + GAV.subi[0] = xsubi[0]; + GAV.subi[1] = xsubi[1]; + GAV.subi[2] = xsubi[2]; + fprintf(logFP, "(%5hu %5hu %5hu)", GAV.subi[0], GAV.subi[1], GAV.subi[2]); + fflush(logFP); + + Zeit = 0.0; + /* highestE = OhighestE = -1000.0; */ + reset_nbList(); + return(1); + } + else { + /* continue simulation */ + int flag = 0; + if( (!GTV.silent) && (GSV.currE <= GSV.stopE+GSV.cut) ) { + if (!GTV.lmin || (lmin==1 && strcmp(GAV.prevform, GAV.currform) != 0)) { + char format[64]; + flag = 1; + sprintf(format, "%%-%ds %%6.2f %%10.3f", strlen(GAV.farbe_full)); + printf(format, GAV.currform, GSV.currE, Zeit); + } + if ( flag && GTV.verbose ) { + int ii, jj; + if (next<0) trans='g'; /* growth */ + else { + ii = neighbor_list[2*next]; + jj = neighbor_list[2*next+1]; + if (abs(ii) < GSV.len) { + if ((ii > 0) && (jj > 0)) trans = 'i'; + else if ((ii < 0) && (jj < 0)) trans = 'd'; + else if ((ii > 0) && (jj < 0)) trans = 's'; + else trans = 'S'; + } else { + if ((ii > 0) && (jj > 0)) trans = 'I'; + else trans = 'D'; + } + } + printf("%4d %c %d", top, trans, lmin); + } + if (flag) printf("\n"); + } + } + + + /* store last lmin seen, so we can avoid printing the same lmin twice */ + if (lmin==1) + strcpy(GAV.prevform, GAV.currform); + +#if 0 + if (lmin==1) { + /* went back to previous lmin */ + if (strcmp(GAV.prevform, GAV.currform) == 0) { + if (OhighestE < highestE) { + highestE = OhighestE; /* delete loop */ + strcpy(highestS, OhighestS); + } + } else { + strcpy(GAV.prevform, GAV.currform); + OhighestE = 10000.; + } + } + + if ( strcmp(GAV.currform, GAV.startform)==0 ) { + OhighestE = highestE = -1000.; + highestS[0] = 0; + } + + /* log highes energy */ + if (GSV.currE > highestE) { + OhighestE = highestE; + highestE = GSV.currE; + strcpy(OhighestS, highestS); + strcpy(highestS, GAV.currform); + } +#endif + + if (next>=0) update_tree(neighbor_list[2*next], neighbor_list[2*next+1]); + else { + clean_up_rl(); ini_or_reset_rl(); + } + + reset_nbList(); + return(0); +} + +/*==========================*/ +static void reset_nbList(void) { + + top = 0; + totalflux = 0.0; + /* meanE = 0.0; */ + lmin = 1; +} + +/*======================*/ +void clean_up_nbList(void){ + + free(neighbor_list); + free(bmf); + fprintf(logFP,"\n"); + fclose(logFP); +} + +/*======================*/ +static void grow_chain(void){ + int newl; + /* note Zeit=0 corresponds to chain length GSV.glen */ + if (Zeit<(GSV.len+1-GSV.glen) * GSV.grow) return; + newl = GSV.len+1; + Zeit = (newl-GSV.glen) * GSV.grow; + top=0; /* prevent structure move in sel_nb */ + + if (GSV.len + c Christoph Flamm and Ivo L Hofacker + {xtof,ivo}@tbi.univie.ac.at + Kinfold: $Name: $ + $Id: nachbar.h,v 1.2 2005/02/16 17:00:48 ivo Exp $ +*/ + +#ifndef NACHBAR_H +#define NACHBAR_H + +/* used in baum.c */ +extern void ini_nbList(int chords); +extern void update_nbList(int i,int j, int iE); + +/* used in main.c */ +extern int sel_nb(void); +extern void clean_up_nbList(void); + +extern void grow_chain(void); +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/nachbar.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Kinfold/nachbar.o new file mode 100755 index 0000000000000000000000000000000000000000..1ebb04335f2c582ad58e1e367e90d8a2b0d0c561 GIT binary patch literal 14412 zcma)i3wTu3x%S$#XPAKrNeCf=1QqO3;M}UVN_)0A+cJ6cDjg(3`i%)&o z-`{^fy><2E?D;P6F!NbP;|C08iou=0Ljwj~pZ~MJ-?jm!j%atsoMu^TwB_hB)2R+4 zgZ7pxl(H!3>PaN*e227!M6&xu*6zwpNA~YaOjS=KtxhjTgvXr4CelyR_NiKYrB)Yb 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RNAforester was written by Matthias + Hoechsmann +- The Kinfold program for stochastic simulation of folding trajectories is + no included in the package, see the Kinfold subdirectory. +- cofolding of two structures now supports suboptimal folding and + partition function folding (still experimental). + ATTENTION: Energies of hybrid structures now inlcude the Duplex-initiation + energy, which was neglected in previous version. +- RNAplfold is a partition function variant of RNALfold. It computes the + mean probability of a (local) base pair averaged over all sequence + windows that contain the pair. +- new utilities to color alignments and consensus structures + +Version 1.5pre +----------- +- ViennaRNA now uses autoconfig generated configure scripts for even better + portability (should compile on any UNIX, Linux, MacOS X, Windows with + Cygwin). +- The new RNAalifold program predicts consensus structures for a set of + aligned sequences. +- Complete suboptimal folding is now integrated in the library. +- Beginning support for co-folding of two strands: energy_of_struct() and + RNAeval can now compute energies of duplex structures. +- RNAcofold predicts hybrid structures of two RNA strands +- RNAduplex predicts hybrid structures, while allowing only inter-molecular + base pairs (useful for finding potential binding sites) +- RNALfold predicts locally stable structures in long sequences. +- Major changes to Perl module. See the pod documentation (perldoc RNA). +- RNAsubopt can do stochastic backtracking to produce samples of suboptimal + structures with Boltzmann statistics. +- New utilities to rotate secondary structure plots and annotate them with + reliability data. +- Various small bug fixes + +Version 1.4 +----------- +- New Turner parameters as described in Mathews et.al. JMB v288, 1999. + Small changes to format of parameter files (old param files won't work!) +- mfe and suboptimal folding will produce only structures without isolated + pairs if noLonelyPairs=1 (-noLP option), for partition function folding + pairs that can only occur as isolated pairs are not formed. +- setting dangles=3 (-d3 option) will allow co-axial stacking of adjacent + helices in mfe folding and energy_of_struct(). + +Version 1.3.1 +------------- +- RNAheat would produce spikes in the specific heat because dangling end + energies did not go smoothly to 0. +- PS dot plots now have an option to use a log scale (edit _dp.ps file + and set logscale to true). + +Version 1.3 +----------- +- Secondary structure plots now use E. Bruccoleri's naview routines for + layout by default. New utility RNAplot produces secondary structure plots + from structures in bracket notation with several options. +- New -d2 option in RNAfold and RNAeval sets dangles=2, which makes + energy_of_struct() and fold() treat dangling ends as in pf_fold(). + -noLP option in RNAfold etc sets noLonelyPairs=1, which avoids most + structures containing lonely base pairs (helices of length 1). +- new utility functions pack_structure() unpack_structure() make_pair_table() + and bp_distance(). RNAdistance adds bp_distance() via -DP switch. +- First release of RNAsubopt for complete suboptimal folding. +- fixed bug in asymmetry penalty for interior loops. +- Default compilation now uses doubles for partition function folding. + +Version 1.2.1 +------------- +- Fixed bug in version 1.2 of the RNAheat program causing overflow errors + for most input sequences. +- The PS_dot_plot() and PS_rna_plot() routines now return an int. The return + value is 0 if the file could not be written, 1 otherwise. +- This version contains the alpha version of a perl5 module, which let's you + access all the capabilities of the Vienna RNA library from perl scripts. + +Version 1.2 +----------- +- New energy parameters from (Walter et.al 1994). +- Energy parameters can be read from file. +- RNAeval and energy_of_struct() support logarithmic energy function for + multi-loops. +- gmlRNA() produces secondary structure drawing in gml (Graph Meta Language). +- Many bug fixes. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile new file mode 100755 index 00000000..e40112b0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile @@ -0,0 +1,319 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# Perl/Makefile. Generated from Makefile.in by configure. + +# Copyright (C) 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, +# 2003, 2004, 2005 Free Software Foundation, Inc. +# This Makefile.in is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + + +SOURCES = RNA.i ptr2array.i Makefile.PL + +srcdir = . +top_srcdir = .. + +pkgdatadir = $(datadir)/ViennaRNA +pkglibdir = $(libdir)/ViennaRNA +pkgincludedir = $(includedir)/ViennaRNA +top_builddir = .. +am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd +INSTALL = /usr/bin/install -c +install_sh_DATA = $(install_sh) -c -m 644 +install_sh_PROGRAM = $(install_sh) -c +install_sh_SCRIPT = $(install_sh) -c +INSTALL_HEADER = $(INSTALL_DATA) +transform = $(program_transform_name) +NORMAL_INSTALL = : +PRE_INSTALL = : +POST_INSTALL = : +NORMAL_UNINSTALL = : +PRE_UNINSTALL = : +POST_UNINSTALL = : +build_triplet = x86_64-unknown-linux-gnu +host_triplet = x86_64-unknown-linux-gnu +subdir = Perl +DIST_COMMON = $(srcdir)/Makefile.am $(srcdir)/Makefile.in +ACLOCAL_M4 = $(top_srcdir)/aclocal.m4 +am__aclocal_m4_deps = $(top_srcdir)/configure.in +am__configure_deps = $(am__aclocal_m4_deps) $(CONFIGURE_DEPENDENCIES) \ + $(ACLOCAL_M4) +mkinstalldirs = $(install_sh) -d +CONFIG_HEADER = $(top_builddir)/config.h +CONFIG_CLEAN_FILES = +DIST_SOURCES = +DISTFILES = $(DIST_COMMON) $(DIST_SOURCES) $(TEXINFOS) $(EXTRA_DIST) +ACLOCAL = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run aclocal-1.9 +AMDEP_FALSE = # +AMDEP_TRUE = +AMTAR = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run tar +AUTOCONF = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoconf +AUTOHEADER = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoheader +AUTOMAKE = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run automake-1.9 +AWK = gawk +CC = gcc +CCDEPMODE = depmode=gcc3 +CFLAGS = -g -O2 +CPP = gcc -E +CPPFLAGS = +CYGPATH_W = echo +DEFS = -DHAVE_CONFIG_H +DEPDIR = .deps +ECHO_C = +ECHO_N = -n +ECHO_T = +EGREP = grep -E +EXEEXT = +INSTALL_DATA = ${INSTALL} -m 644 +INSTALL_PROGRAM = ${INSTALL} +INSTALL_SCRIPT = ${INSTALL} +INSTALL_STRIP_PROGRAM = ${SHELL} $(install_sh) -c -s +ISODATE = 2006-06-13 +LDFLAGS = +LIBOBJS = +LIBS = +LTLIBOBJS = +MAKEINFO = ${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run makeinfo +MAKE_CLUSTER_FALSE = +MAKE_CLUSTER_TRUE = # +MAKE_FORESTER_FALSE = # +MAKE_FORESTER_TRUE = +MAKE_KINFOLD_FALSE = # +MAKE_KINFOLD_TRUE = +MAKE_PERL_EXT_FALSE = # +MAKE_PERL_EXT_TRUE = +OBJEXT = o +PACKAGE = ViennaRNA +PACKAGE_BUGREPORT = rna@tbi.univie.ac.at +PACKAGE_NAME = ViennaRNA +PACKAGE_STRING = ViennaRNA 1.6 +PACKAGE_TARNAME = ViennaRNA +PACKAGE_VERSION = 1.6 +PATH_SEPARATOR = : +PerlCmd = /usr/bin/perl +RANLIB = ranlib +SET_MAKE = +SHELL = /bin/sh +STRIP = +VERSION = 1.6 +ac_ct_CC = gcc +ac_ct_RANLIB = ranlib +ac_ct_STRIP = +am__fastdepCC_FALSE = # +am__fastdepCC_TRUE = +am__include = include +am__leading_dot = . +am__quote = +am__tar = ${AMTAR} chof - "$$tardir" +am__untar = ${AMTAR} xf - +bindir = ${exec_prefix}/bin +build = x86_64-unknown-linux-gnu +build_alias = +build_cpu = x86_64 +build_os = linux-gnu +build_vendor = unknown +datadir = ${prefix}/share +exec_prefix = ${prefix} +host = x86_64-unknown-linux-gnu +host_alias = +host_cpu = x86_64 +host_os = linux-gnu +host_vendor = unknown +includedir = ${prefix}/include +infodir = ${prefix}/info +install_sh = /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/install-sh +libdir = ${exec_prefix}/lib +libexecdir = ${exec_prefix}/libexec +localstatedir = ${prefix}/var +mandir = ${prefix}/man +mkdir_p = mkdir -p -- +oldincludedir = /usr/include +prefix = /usr/local +program_transform_name = s,x,x, +sbindir = ${exec_prefix}/sbin +sharedstatedir = ${prefix}/com +subdirs = RNAforester Kinfold +sysconfdir = ${prefix}/etc +target_alias = +SOURCES = RNA.i ptr2array.i Makefile.PL +EXTRA_DIST = RNA.pm RNA_wrap.c RNAfold.pl test.pl RNAfold.cgi RNA.i Makefile.PL +all: all-am + +.SUFFIXES: +$(srcdir)/Makefile.in: $(srcdir)/Makefile.am $(am__configure_deps) + @for dep in $?; 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s/SWIGTYPE_p_unsigned_short/SWIGTYPE_p_short/' RNA_wrap.c + +all-local: RNA_wrap.c Makefile.perl + $(MAKE) -f Makefile.perl + +install-exec-local: all-local + $(MAKE) -f Makefile.perl install + +check-local: all-local + $(MAKE) -f Makefile.perl test + +mostlyclean-local: Makefile.perl + $(MAKE) -f Makefile.perl clean +# Tell versions [3.59,3.63) of GNU make to not export all variables. +# Otherwise a system limit (for SysV at least) may be exceeded. +.NOEXPORT: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.PL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.PL new file mode 100755 index 00000000..bb18cfc6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.PL @@ -0,0 +1,12 @@ +# File : Makefile.PL +use ExtUtils::MakeMaker; +WriteMakefile( + MAKEFILE => "Makefile.perl", + NAME => "RNA", + LIBS => ["-lm"], + MYEXTLIB => "../lib/libRNA.a", + PM => {"RNA.pm", '$(INST_LIBDIR)/RNA.pm'}, + OBJECT => "RNA_wrap.o", + AUTHOR => 'Ivo Hofacker ', + VERSION => 0.2 +); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.am b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.am new file mode 100755 index 00000000..a6a1474a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.am @@ -0,0 +1,23 @@ +SOURCES = RNA.i ptr2array.i Makefile.PL + +EXTRA_DIST = RNA.pm RNA_wrap.c RNAfold.pl test.pl RNAfold.cgi RNA.i Makefile.PL + +Makefile.perl: Makefile.PL Makefile + @PerlCmd@ Makefile.PL + +# the perl command repairs some errors in the SWIG CVS version +RNA_wrap.c: RNA.i + swig -perl5 -shadow RNA.i +# @PerlCmd@ -i -npe 's/\A\s+\;\s+\Z//; s/SWIGTYPE_p_unsigned_short/SWIGTYPE_p_short/' RNA_wrap.c + +all-local: RNA_wrap.c Makefile.perl + $(MAKE) -f Makefile.perl + +install-exec-local: all-local + $(MAKE) -f Makefile.perl install + +check-local: all-local + $(MAKE) -f Makefile.perl test + +mostlyclean-local: Makefile.perl + $(MAKE) -f Makefile.perl clean diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.in new file mode 100755 index 00000000..0acb53e4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.in @@ -0,0 +1,319 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# @configure_input@ + +# Copyright (C) 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, +# 2003, 2004, 2005 Free Software Foundation, Inc. +# This Makefile.in is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + +@SET_MAKE@ +SOURCES = RNA.i ptr2array.i Makefile.PL + +srcdir = @srcdir@ +top_srcdir = @top_srcdir@ +VPATH = @srcdir@ +pkgdatadir = $(datadir)/@PACKAGE@ +pkglibdir = $(libdir)/@PACKAGE@ +pkgincludedir = $(includedir)/@PACKAGE@ +top_builddir = .. +am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd +INSTALL = @INSTALL@ +install_sh_DATA = $(install_sh) -c -m 644 +install_sh_PROGRAM = $(install_sh) -c +install_sh_SCRIPT = $(install_sh) -c +INSTALL_HEADER = $(INSTALL_DATA) +transform = $(program_transform_name) +NORMAL_INSTALL = : +PRE_INSTALL = : +POST_INSTALL = : +NORMAL_UNINSTALL = : +PRE_UNINSTALL = : +POST_UNINSTALL = : +build_triplet = @build@ +host_triplet = @host@ +subdir = Perl +DIST_COMMON = $(srcdir)/Makefile.am $(srcdir)/Makefile.in +ACLOCAL_M4 = $(top_srcdir)/aclocal.m4 +am__aclocal_m4_deps = $(top_srcdir)/configure.in +am__configure_deps = $(am__aclocal_m4_deps) $(CONFIGURE_DEPENDENCIES) \ + $(ACLOCAL_M4) +mkinstalldirs = $(install_sh) -d +CONFIG_HEADER = $(top_builddir)/config.h +CONFIG_CLEAN_FILES = +DIST_SOURCES = +DISTFILES = $(DIST_COMMON) $(DIST_SOURCES) $(TEXINFOS) $(EXTRA_DIST) +ACLOCAL = @ACLOCAL@ +AMDEP_FALSE = @AMDEP_FALSE@ +AMDEP_TRUE = @AMDEP_TRUE@ +AMTAR = @AMTAR@ +AUTOCONF = @AUTOCONF@ +AUTOHEADER = @AUTOHEADER@ +AUTOMAKE = @AUTOMAKE@ +AWK = @AWK@ +CC = @CC@ +CCDEPMODE = @CCDEPMODE@ +CFLAGS = @CFLAGS@ +CPP = @CPP@ +CPPFLAGS = @CPPFLAGS@ +CYGPATH_W = @CYGPATH_W@ +DEFS = @DEFS@ +DEPDIR = @DEPDIR@ +ECHO_C = @ECHO_C@ +ECHO_N = @ECHO_N@ +ECHO_T = @ECHO_T@ +EGREP = @EGREP@ +EXEEXT = @EXEEXT@ +INSTALL_DATA = @INSTALL_DATA@ +INSTALL_PROGRAM = @INSTALL_PROGRAM@ +INSTALL_SCRIPT = @INSTALL_SCRIPT@ +INSTALL_STRIP_PROGRAM = @INSTALL_STRIP_PROGRAM@ +ISODATE = @ISODATE@ +LDFLAGS = @LDFLAGS@ +LIBOBJS = @LIBOBJS@ +LIBS = @LIBS@ +LTLIBOBJS = @LTLIBOBJS@ +MAKEINFO = @MAKEINFO@ +MAKE_CLUSTER_FALSE = @MAKE_CLUSTER_FALSE@ +MAKE_CLUSTER_TRUE = @MAKE_CLUSTER_TRUE@ +MAKE_FORESTER_FALSE = @MAKE_FORESTER_FALSE@ +MAKE_FORESTER_TRUE = @MAKE_FORESTER_TRUE@ +MAKE_KINFOLD_FALSE = @MAKE_KINFOLD_FALSE@ +MAKE_KINFOLD_TRUE = @MAKE_KINFOLD_TRUE@ +MAKE_PERL_EXT_FALSE = @MAKE_PERL_EXT_FALSE@ +MAKE_PERL_EXT_TRUE = @MAKE_PERL_EXT_TRUE@ +OBJEXT = @OBJEXT@ +PACKAGE = @PACKAGE@ +PACKAGE_BUGREPORT = @PACKAGE_BUGREPORT@ +PACKAGE_NAME = @PACKAGE_NAME@ +PACKAGE_STRING = @PACKAGE_STRING@ +PACKAGE_TARNAME = @PACKAGE_TARNAME@ +PACKAGE_VERSION = @PACKAGE_VERSION@ +PATH_SEPARATOR = @PATH_SEPARATOR@ +PerlCmd = @PerlCmd@ +RANLIB = @RANLIB@ +SET_MAKE = @SET_MAKE@ +SHELL = @SHELL@ +STRIP = @STRIP@ +VERSION = @VERSION@ +ac_ct_CC = @ac_ct_CC@ +ac_ct_RANLIB = @ac_ct_RANLIB@ +ac_ct_STRIP = @ac_ct_STRIP@ +am__fastdepCC_FALSE = @am__fastdepCC_FALSE@ +am__fastdepCC_TRUE = @am__fastdepCC_TRUE@ +am__include = @am__include@ +am__leading_dot = @am__leading_dot@ +am__quote = @am__quote@ +am__tar = @am__tar@ +am__untar = @am__untar@ +bindir = @bindir@ +build = @build@ +build_alias = @build_alias@ +build_cpu = @build_cpu@ +build_os = @build_os@ +build_vendor = @build_vendor@ +datadir = @datadir@ +exec_prefix = @exec_prefix@ +host = @host@ +host_alias = @host_alias@ +host_cpu = @host_cpu@ +host_os = @host_os@ +host_vendor = @host_vendor@ +includedir = @includedir@ +infodir = @infodir@ +install_sh = @install_sh@ +libdir = @libdir@ +libexecdir = @libexecdir@ +localstatedir = @localstatedir@ +mandir = @mandir@ +mkdir_p = @mkdir_p@ +oldincludedir = @oldincludedir@ +prefix = @prefix@ +program_transform_name = @program_transform_name@ +sbindir = @sbindir@ +sharedstatedir = @sharedstatedir@ +subdirs = @subdirs@ +sysconfdir = @sysconfdir@ +target_alias = @target_alias@ +SOURCES = RNA.i ptr2array.i Makefile.PL +EXTRA_DIST = RNA.pm RNA_wrap.c RNAfold.pl test.pl RNAfold.cgi RNA.i Makefile.PL +all: all-am + +.SUFFIXES: +$(srcdir)/Makefile.in: $(srcdir)/Makefile.am $(am__configure_deps) + @for dep in $?; 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s/SWIGTYPE_p_unsigned_short/SWIGTYPE_p_short/' RNA_wrap.c + +all-local: RNA_wrap.c Makefile.perl + $(MAKE) -f Makefile.perl + +install-exec-local: all-local + $(MAKE) -f Makefile.perl install + +check-local: all-local + $(MAKE) -f Makefile.perl test + +mostlyclean-local: Makefile.perl + $(MAKE) -f Makefile.perl clean +# Tell versions [3.59,3.63) of GNU make to not export all variables. +# Otherwise a system limit (for SysV at least) may be exceeded. +.NOEXPORT: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.perl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.perl new file mode 100755 index 00000000..a8492194 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/Makefile.perl @@ -0,0 +1,830 @@ +# This Makefile is for the RNA extension to perl. +# +# It was generated automatically by MakeMaker version +# 6.03 (Revision: 1.63) from the contents of +# Makefile.PL. Don't edit this file, edit Makefile.PL instead. +# +# ANY CHANGES MADE HERE WILL BE LOST! +# +# MakeMaker ARGV: () +# +# MakeMaker Parameters: + +# AUTHOR => q[Ivo Hofacker ] +# LIBS => [q[-lm]] +# MAKEFILE => q[Makefile.perl] +# MYEXTLIB => q[../lib/libRNA.a] +# NAME => q[RNA] +# OBJECT => q[RNA_wrap.o] +# PM => { RNA.pm=>q[$(INST_LIBDIR)/RNA.pm] } +# VERSION => q[0.2] + +# --- MakeMaker post_initialize section: + + +# --- MakeMaker const_config section: + +# These definitions are from config.sh (via /usr/lib/perl5/5.8.0/i386-linux-thread-multi/Config.pm) + +# They may have been overridden via Makefile.PL or on the command line +AR = ar +CC = gcc +CCCDLFLAGS = -fPIC +CCDLFLAGS = -rdynamic -Wl,-rpath,/usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE +DLEXT = so +DLSRC = dl_dlopen.xs +LD = gcc +LDDLFLAGS = -shared -L/usr/local/lib +LDFLAGS = -L/usr/local/lib +LIBC = /lib/libc-2.3.2.so +LIB_EXT = .a +OBJ_EXT = .o +OSNAME = linux +OSVERS = 2.4.21-23.elsmp +RANLIB = : +SO = so +EXE_EXT = +FULL_AR = /usr/bin/ar + + +# --- MakeMaker constants section: +AR_STATIC_ARGS = cr +NAME = RNA +DISTNAME = RNA +NAME_SYM = RNA +VERSION = 0.2 +VERSION_SYM = 0_2 +XS_VERSION = 0.2 +INST_ARCHLIB = blib/arch +INST_SCRIPT = blib/script +INST_BIN = blib/bin +INST_LIB = blib/lib +INSTALLDIRS = site +PREFIX = /usr +SITEPREFIX = /usr +VENDORPREFIX = /usr +INSTALLPRIVLIB = /usr/lib/perl5/5.8.0 +INSTALLSITELIB = /usr/lib/perl5/site_perl/5.8.0 +INSTALLVENDORLIB = /usr/lib/perl5/vendor_perl/5.8.0 +INSTALLARCHLIB = /usr/lib/perl5/5.8.0/i386-linux-thread-multi +INSTALLSITEARCH = /usr/lib/perl5/site_perl/5.8.0/i386-linux-thread-multi +INSTALLVENDORARCH = /usr/lib/perl5/vendor_perl/5.8.0/i386-linux-thread-multi +INSTALLBIN = /usr/bin +INSTALLSITEBIN = /usr/bin +INSTALLVENDORBIN = /usr/bin +INSTALLSCRIPT = /usr/bin +PERL_LIB = /usr/lib/perl5/5.8.0 +PERL_ARCHLIB = /usr/lib/perl5/5.8.0/i386-linux-thread-multi +SITELIBEXP = /usr/lib/perl5/site_perl/5.8.0 +SITEARCHEXP = /usr/lib/perl5/site_perl/5.8.0/i386-linux-thread-multi +LIBPERL_A = libperl.a +MYEXTLIB = ../lib/libRNA.a +FIRST_MAKEFILE = Makefile +MAKE_APERL_FILE = Makefile.aperl +PERLMAINCC = $(CC) +PERL_INC = /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE +PERL = /usr/bin/perl +FULLPERL = /usr/bin/perl +PERLRUN = $(PERL) +FULLPERLRUN = $(FULLPERL) +PERLRUNINST = $(PERLRUN) "-I$(INST_ARCHLIB)" "-I$(INST_LIB)" +FULLPERLRUNINST = $(FULLPERLRUN) "-I$(INST_ARCHLIB)" "-I$(INST_LIB)" +ABSPERL = $(PERL) +ABSPERLRUN = $(ABSPERL) +ABSPERLRUNINST = $(ABSPERLRUN) "-I$(INST_ARCHLIB)" "-I$(INST_LIB)" +FULL_AR = /usr/bin/ar +PERL_CORE = 0 +NOOP = $(SHELL) -c true +NOECHO = @ + +VERSION_MACRO = VERSION +DEFINE_VERSION = -D$(VERSION_MACRO)=\"$(VERSION)\" +XS_VERSION_MACRO = XS_VERSION +XS_DEFINE_VERSION = -D$(XS_VERSION_MACRO)=\"$(XS_VERSION)\" +PERL_MALLOC_DEF = -DPERL_EXTMALLOC_DEF -Dmalloc=Perl_malloc -Dfree=Perl_mfree -Drealloc=Perl_realloc -Dcalloc=Perl_calloc + +MAKEMAKER = /usr/lib/perl5/5.8.0/ExtUtils/MakeMaker.pm +MM_VERSION = 6.03 + +# FULLEXT = Pathname for extension directory (eg Foo/Bar/Oracle). +# BASEEXT = Basename part of FULLEXT. May be just equal FULLEXT. (eg Oracle) +# PARENT_NAME = NAME without BASEEXT and no trailing :: (eg Foo::Bar) +# DLBASE = Basename part of dynamic library. May be just equal BASEEXT. +FULLEXT = RNA +BASEEXT = RNA +PARENT_NAME = +DLBASE = $(BASEEXT) +OBJECT = RNA_wrap$(OBJ_EXT) +LDFROM = $(OBJECT) +LINKTYPE = dynamic + +# Handy lists of source code files: +XS_FILES= +C_FILES = RNA_wrap.c +O_FILES = RNA_wrap.o +H_FILES = +MAN1PODS = +MAN3PODS = RNA.pm +INST_MAN1DIR = blib/man1 +MAN1EXT = 1 +INSTALLMAN1DIR = /usr/share/man/man1 +INSTALLSITEMAN1DIR = /usr/share/man/man1 +INSTALLVENDORMAN1DIR = /usr/share/man/man1 +INST_MAN3DIR = blib/man3 +MAN3EXT = 3pm +INSTALLMAN3DIR = /usr/share/man/man3 +INSTALLSITEMAN3DIR = /usr/share/man/man3 +INSTALLVENDORMAN3DIR = /usr/share/man/man3 +PERM_RW = 644 +PERM_RWX = 755 + +# work around a famous dec-osf make(1) feature(?): +makemakerdflt: all + +.SUFFIXES: .xs .c .C .cpp .i .s .cxx .cc $(OBJ_EXT) + +# Nick wanted to get rid of .PRECIOUS. I don't remember why. I seem to recall, that +# some make implementations will delete the Makefile when we rebuild it. Because +# we call false(1) when we rebuild it. So make(1) is not completely wrong when it +# does so. Our milage may vary. +# .PRECIOUS: Makefile # seems to be not necessary anymore + +.PHONY: all config static dynamic test linkext manifest + +# Where is the Config information that we are using/depend on +CONFIGDEP = $(PERL_ARCHLIB)/Config.pm $(PERL_INC)/config.h + +# Where to put things: +INST_LIBDIR = $(INST_LIB) +INST_ARCHLIBDIR = $(INST_ARCHLIB) + +INST_AUTODIR = $(INST_LIB)/auto/$(FULLEXT) +INST_ARCHAUTODIR = $(INST_ARCHLIB)/auto/$(FULLEXT) + +INST_STATIC = $(INST_ARCHAUTODIR)/$(BASEEXT)$(LIB_EXT) +INST_DYNAMIC = $(INST_ARCHAUTODIR)/$(DLBASE).$(DLEXT) +INST_BOOT = $(INST_ARCHAUTODIR)/$(BASEEXT).bs + +EXPORT_LIST = + +PERL_ARCHIVE = + +PERL_ARCHIVE_AFTER = + +TO_INST_PM = RNA.pm + +PM_TO_BLIB = RNA.pm \ + $(INST_LIBDIR)/RNA.pm + + +# --- MakeMaker tool_autosplit section: +# Usage: $(AUTOSPLITFILE) FileToSplit AutoDirToSplitInto +AUTOSPLITFILE = $(PERLRUN) -e 'use AutoSplit; autosplit($$ARGV[0], $$ARGV[1], 0, 1, 1) ;' + + + +# --- MakeMaker tool_xsubpp section: + +XSUBPPDIR = /usr/lib/perl5/5.8.0/ExtUtils +XSUBPP = $(XSUBPPDIR)/xsubpp +XSPROTOARG = +XSUBPPDEPS = $(XSUBPPDIR)/typemap $(XSUBPP) +XSUBPPARGS = -typemap $(XSUBPPDIR)/typemap +XSUBPP_EXTRA_ARGS = + + +# --- MakeMaker tools_other section: + +SHELL = /bin/sh +CHMOD = chmod +CP = cp +LD = gcc +MV = mv +NOOP = $(SHELL) -c true +RM_F = rm -f +RM_RF = rm -rf +TEST_F = test -f +TOUCH = touch +UMASK_NULL = umask 0 +DEV_NULL = > /dev/null 2>&1 + +# The following is a portable way to say mkdir -p +# To see which directories are created, change the if 0 to if 1 +MKPATH = $(PERLRUN) "-MExtUtils::Command" -e mkpath + +# This helps us to minimize the effect of the .exists files A yet +# better solution would be to have a stable file in the perl +# distribution with a timestamp of zero. But this solution doesn't +# need any changes to the core distribution and works with older perls +EQUALIZE_TIMESTAMP = $(PERLRUN) "-MExtUtils::Command" -e eqtime + +# Here we warn users that an old packlist file was found somewhere, +# and that they should call some uninstall routine +WARN_IF_OLD_PACKLIST = $(PERL) -we 'exit unless -f $$ARGV[0];' \ +-e 'print "WARNING: I have found an old package in\n";' \ +-e 'print "\t$$ARGV[0].\n";' \ +-e 'print "Please make sure the two installations are not conflicting\n";' + +UNINST=0 +VERBINST=0 + +MOD_INSTALL = $(PERL) "-I$(INST_LIB)" "-I$(PERL_LIB)" "-MExtUtils::Install" \ +-e "install({@ARGV},'$(VERBINST)',0,'$(UNINST)');" + +DOC_INSTALL = $(PERL) -e '$$\="\n\n";' \ +-e 'print "=head2 ", scalar(localtime), ": C<", shift, ">", " L<", $$arg=shift, "|", $$arg, ">";' \ +-e 'print "=over 4";' \ +-e 'while (defined($$key = shift) and defined($$val = shift)){print "=item *";print "C<$$key: $$val>";}' \ +-e 'print "=back";' + +UNINSTALL = $(PERLRUN) "-MExtUtils::Install" \ +-e 'uninstall($$ARGV[0],1,1); print "\nUninstall is deprecated. Please check the";' \ +-e 'print " packlist above carefully.\n There may be errors. Remove the";' \ +-e 'print " appropriate files manually.\n Sorry for the inconveniences.\n"' + + +# --- MakeMaker dist section: +ZIPFLAGS = -r +TO_UNIX = @$(NOOP) +TAR = tar +POSTOP = @$(NOOP) +ZIP = zip +DIST_DEFAULT = tardist +CI = ci -u +SHAR = shar +COMPRESS = gzip --best +DIST_CP = best +PREOP = @$(NOOP) +TARFLAGS = cvf +DISTVNAME = $(DISTNAME)-$(VERSION) +SUFFIX = .gz +RCS_LABEL = rcs -Nv$(VERSION_SYM): -q + + +# --- MakeMaker macro section: + + +# --- MakeMaker depend section: + + +# --- MakeMaker cflags section: + +CCFLAGS = -D_REENTRANT -D_GNU_SOURCE -DTHREADS_HAVE_PIDS -DDEBUGGING -fno-strict-aliasing -I/usr/local/include -D_LARGEFILE_SOURCE -D_FILE_OFFSET_BITS=64 -I/usr/include/gdbm +OPTIMIZE = -O2 -g -pipe -march=i386 -mcpu=i686 +PERLTYPE = +MPOLLUTE = + + +# --- MakeMaker const_loadlibs section: + +# RNA might depend on some other libraries: +# See ExtUtils::Liblist for details +# +EXTRALIBS = -lm +LDLOADLIBS = -lm +BSLOADLIBS = +LD_RUN_PATH = /lib + + +# --- MakeMaker const_cccmd section: +CCCMD = $(CC) -c $(PASTHRU_INC) $(INC) \ + $(CCFLAGS) $(OPTIMIZE) \ + $(PERLTYPE) $(MPOLLUTE) $(DEFINE_VERSION) \ + $(XS_DEFINE_VERSION) + +# --- MakeMaker post_constants section: + + +# --- MakeMaker pasthru section: + +PASTHRU = LIB="$(LIB)"\ + LIBPERL_A="$(LIBPERL_A)"\ + LINKTYPE="$(LINKTYPE)"\ + PREFIX="$(PREFIX)"\ + OPTIMIZE="$(OPTIMIZE)"\ + PASTHRU_DEFINE="$(PASTHRU_DEFINE)"\ + PASTHRU_INC="$(PASTHRU_INC)" + + +# --- MakeMaker c_o section: + +.c.i: + gcc -E -c $(PASTHRU_INC) $(INC) \ + $(CCFLAGS) $(OPTIMIZE) \ + $(PERLTYPE) $(MPOLLUTE) $(DEFINE_VERSION) \ + $(XS_DEFINE_VERSION) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.c > $*.i + +.c.s: + $(CCCMD) -S $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.c + +.c$(OBJ_EXT): + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.c + +.C$(OBJ_EXT): + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.C + +.cpp$(OBJ_EXT): + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.cpp + +.cxx$(OBJ_EXT): + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.cxx + +.cc$(OBJ_EXT): + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.cc + + +# --- MakeMaker xs_c section: + +.xs.c: + $(PERLRUN) $(XSUBPP) $(XSPROTOARG) $(XSUBPPARGS) $(XSUBPP_EXTRA_ARGS) $*.xs > $*.xsc && $(MV) $*.xsc $*.c + + +# --- MakeMaker xs_o section: + +.xs$(OBJ_EXT): + $(PERLRUN) $(XSUBPP) $(XSPROTOARG) $(XSUBPPARGS) $*.xs > $*.xsc && $(MV) $*.xsc $*.c + $(CCCMD) $(CCCDLFLAGS) "-I$(PERL_INC)" $(PASTHRU_DEFINE) $(DEFINE) $*.c + + +# --- MakeMaker top_targets section: + +all :: pure_all manifypods + @$(NOOP) + +pure_all :: config pm_to_blib subdirs linkext + @$(NOOP) + +subdirs :: $(MYEXTLIB) + @$(NOOP) + +config :: Makefile.perl $(INST_LIBDIR)/.exists + @$(NOOP) + +config :: $(INST_ARCHAUTODIR)/.exists + @$(NOOP) + +config :: $(INST_AUTODIR)/.exists + @$(NOOP) + +$(INST_AUTODIR)/.exists :: /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h + @$(MKPATH) $(INST_AUTODIR) + @$(EQUALIZE_TIMESTAMP) /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h $(INST_AUTODIR)/.exists + + -@$(CHMOD) $(PERM_RWX) $(INST_AUTODIR) + +$(INST_LIBDIR)/.exists :: /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h + @$(MKPATH) $(INST_LIBDIR) + @$(EQUALIZE_TIMESTAMP) /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h $(INST_LIBDIR)/.exists + + -@$(CHMOD) $(PERM_RWX) $(INST_LIBDIR) + +$(INST_ARCHAUTODIR)/.exists :: /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h + @$(MKPATH) $(INST_ARCHAUTODIR) + @$(EQUALIZE_TIMESTAMP) /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h $(INST_ARCHAUTODIR)/.exists + + -@$(CHMOD) $(PERM_RWX) $(INST_ARCHAUTODIR) + +config :: $(INST_MAN3DIR)/.exists + @$(NOOP) + + +$(INST_MAN3DIR)/.exists :: /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h + @$(MKPATH) $(INST_MAN3DIR) + @$(EQUALIZE_TIMESTAMP) /usr/lib/perl5/5.8.0/i386-linux-thread-multi/CORE/perl.h $(INST_MAN3DIR)/.exists + + -@$(CHMOD) $(PERM_RWX) $(INST_MAN3DIR) + +help: + perldoc ExtUtils::MakeMaker + + +# --- MakeMaker linkext section: + +linkext :: $(LINKTYPE) + @$(NOOP) + + +# --- MakeMaker dlsyms section: + + +# --- MakeMaker dynamic section: + +## $(INST_PM) has been moved to the all: target. +## It remains here for awhile to allow for old usage: "make dynamic" +#dynamic :: Makefile.perl $(INST_DYNAMIC) $(INST_BOOT) $(INST_PM) +dynamic :: Makefile.perl $(INST_DYNAMIC) $(INST_BOOT) + @$(NOOP) + + +# --- MakeMaker dynamic_bs section: + +BOOTSTRAP = RNA.bs + +# As Mkbootstrap might not write a file (if none is required) +# we use touch to prevent make continually trying to remake it. +# The DynaLoader only reads a non-empty file. +$(BOOTSTRAP): Makefile.perl $(INST_ARCHAUTODIR)/.exists + @echo "Running Mkbootstrap for $(NAME) ($(BSLOADLIBS))" + @$(PERLRUN) \ + "-MExtUtils::Mkbootstrap" \ + -e "Mkbootstrap('$(BASEEXT)','$(BSLOADLIBS)');" + @$(TOUCH) $(BOOTSTRAP) + $(CHMOD) $(PERM_RW) $@ + +$(INST_BOOT): $(BOOTSTRAP) $(INST_ARCHAUTODIR)/.exists + @rm -rf $(INST_BOOT) + -cp $(BOOTSTRAP) $(INST_BOOT) + $(CHMOD) $(PERM_RW) $@ + + +# --- MakeMaker dynamic_lib section: + +# This section creates the dynamically loadable $(INST_DYNAMIC) +# from $(OBJECT) and possibly $(MYEXTLIB). +ARMAYBE = : +OTHERLDFLAGS = +INST_DYNAMIC_DEP = + +$(INST_DYNAMIC): $(OBJECT) $(MYEXTLIB) $(BOOTSTRAP) $(INST_ARCHAUTODIR)/.exists $(EXPORT_LIST) $(PERL_ARCHIVE) $(PERL_ARCHIVE_AFTER) $(INST_DYNAMIC_DEP) + $(RM_F) $@ + LD_RUN_PATH="$(LD_RUN_PATH)" $(LD) $(LDDLFLAGS) $(LDFROM) $(OTHERLDFLAGS) -o $@ $(MYEXTLIB) $(PERL_ARCHIVE) $(LDLOADLIBS) $(PERL_ARCHIVE_AFTER) $(EXPORT_LIST) + $(CHMOD) $(PERM_RWX) $@ + + +# --- MakeMaker static section: + +## $(INST_PM) has been moved to the all: target. +## It remains here for awhile to allow for old usage: "make static" +#static :: Makefile.perl $(INST_STATIC) $(INST_PM) +static :: Makefile.perl $(INST_STATIC) + @$(NOOP) + + +# --- MakeMaker static_lib section: + +$(INST_STATIC): $(OBJECT) $(MYEXTLIB) $(INST_ARCHAUTODIR)/.exists + $(RM_RF) $@ + cp $(MYEXTLIB) $@ + $(FULL_AR) $(AR_STATIC_ARGS) $@ $(OBJECT) && $(RANLIB) $@ + $(CHMOD) $(PERM_RWX) $@ + @echo "$(EXTRALIBS)" > $(INST_ARCHAUTODIR)/extralibs.ld + + + +# --- MakeMaker manifypods section: +POD2MAN_EXE = /usr/bin/pod2man +POD2MAN = $(PERL) -we '%m=@ARGV;for (keys %m){' \ +-e 'next if -e $$m{$$_} && -M $$m{$$_} < -M $$_ && -M $$m{$$_} < -M "Makefile.perl";' \ +-e 'print "Manifying $$m{$$_}\n";' \ +-e 'system(q[$(PERLRUN) $(POD2MAN_EXE) ].qq[$$_>$$m{$$_}])==0 or warn "Couldn\047t install $$m{$$_}\n";' \ +-e 'chmod(oct($(PERM_RW)), $$m{$$_}) or warn "chmod $(PERM_RW) $$m{$$_}: $$!\n";}' + +manifypods : pure_all RNA.pm + @$(POD2MAN) \ + RNA.pm \ + $(INST_MAN3DIR)/RNA.$(MAN3EXT) + +# --- MakeMaker processPL section: + + +# --- MakeMaker installbin section: + + +# --- MakeMaker subdirs section: + +# none + +# --- MakeMaker clean section: + +# Delete temporary files but do not touch installed files. We don't delete +# the Makefile here so a later make realclean still has a makefile to use. + +clean :: + -rm -rf ./blib $(MAKE_APERL_FILE) $(INST_ARCHAUTODIR)/extralibs.all perlmain.c tmon.out mon.out so_locations pm_to_blib *$(OBJ_EXT) *$(LIB_EXT) perl.exe perl perl$(EXE_EXT) $(BOOTSTRAP) $(BASEEXT).bso $(BASEEXT).def lib$(BASEEXT).def $(BASEEXT).exp $(BASEEXT).x core core.*perl.*.? *perl.core + -mv Makefile.perl Makefile.perl.old $(DEV_NULL) + + +# --- MakeMaker realclean section: + +# Delete temporary files (via clean) and also delete installed files +realclean purge :: clean + rm -rf $(INST_AUTODIR) $(INST_ARCHAUTODIR) + rm -rf $(DISTVNAME) + rm -f $(INST_DYNAMIC) $(INST_BOOT) + rm -f $(INST_STATIC) + rm -f $(INST_LIBDIR)/RNA.pm + rm -rf Makefile.perl Makefile.perl.old + + +# --- MakeMaker dist_basics section: +distclean :: realclean distcheck + $(NOECHO) $(NOOP) + +distcheck : + $(PERLRUN) "-MExtUtils::Manifest=fullcheck" -e fullcheck + +skipcheck : + $(PERLRUN) "-MExtUtils::Manifest=skipcheck" -e skipcheck + +manifest : + $(PERLRUN) "-MExtUtils::Manifest=mkmanifest" -e mkmanifest + +veryclean : realclean + $(RM_F) *~ *.orig */*~ */*.orig + + + +# --- MakeMaker dist_core section: + +dist : $(DIST_DEFAULT) + @$(PERL) -le 'print "Warning: Makefile possibly out of date with $$vf" if ' \ + -e '-e ($$vf="$(VERSION_FROM)") and -M $$vf < -M "Makefile.perl";' + +tardist : $(DISTVNAME).tar$(SUFFIX) + +zipdist : $(DISTVNAME).zip + +$(DISTVNAME).tar$(SUFFIX) : distdir + $(PREOP) + $(TO_UNIX) + $(TAR) $(TARFLAGS) $(DISTVNAME).tar $(DISTVNAME) + $(RM_RF) $(DISTVNAME) + $(COMPRESS) $(DISTVNAME).tar + $(POSTOP) + +$(DISTVNAME).zip : distdir + $(PREOP) + $(ZIP) $(ZIPFLAGS) $(DISTVNAME).zip $(DISTVNAME) + $(RM_RF) $(DISTVNAME) + $(POSTOP) + +uutardist : $(DISTVNAME).tar$(SUFFIX) + uuencode $(DISTVNAME).tar$(SUFFIX) \ + $(DISTVNAME).tar$(SUFFIX) > \ + $(DISTVNAME).tar$(SUFFIX)_uu + +shdist : distdir + $(PREOP) + $(SHAR) $(DISTVNAME) > $(DISTVNAME).shar + $(RM_RF) $(DISTVNAME) + $(POSTOP) + + +# --- MakeMaker dist_dir section: +distdir : + $(RM_RF) $(DISTVNAME) + $(PERLRUN) "-MExtUtils::Manifest=manicopy,maniread" \ + -e "manicopy(maniread(),'$(DISTVNAME)', '$(DIST_CP)');" + + + +# --- MakeMaker dist_test section: + +disttest : distdir + cd $(DISTVNAME) && $(ABSPERLRUN) Makefile.PL + cd $(DISTVNAME) && $(MAKE) $(PASTHRU) + cd $(DISTVNAME) && $(MAKE) test $(PASTHRU) + + +# --- MakeMaker dist_ci section: + +ci : + $(PERLRUN) "-MExtUtils::Manifest=maniread" \ + -e "@all = keys %{ maniread() };" \ + -e 'print("Executing $(CI) @all\n"); system("$(CI) @all");' \ + -e 'print("Executing $(RCS_LABEL) ...\n"); system("$(RCS_LABEL) @all");' + + +# --- MakeMaker install section: + +install :: all pure_install doc_install + +install_perl :: all pure_perl_install doc_perl_install + +install_site :: all pure_site_install doc_site_install + +install_vendor :: all pure_vendor_install doc_vendor_install + +pure_install :: pure_$(INSTALLDIRS)_install + +doc_install :: doc_$(INSTALLDIRS)_install + @echo Appending installation info to $(INSTALLARCHLIB)/perllocal.pod + +pure__install : pure_site_install + @echo INSTALLDIRS not defined, defaulting to INSTALLDIRS=site + +doc__install : doc_site_install + @echo INSTALLDIRS not defined, defaulting to INSTALLDIRS=site + +pure_perl_install :: + @$(MOD_INSTALL) \ + read $(PERL_ARCHLIB)/auto/$(FULLEXT)/.packlist \ + write $(INSTALLARCHLIB)/auto/$(FULLEXT)/.packlist \ + $(INST_LIB) $(INSTALLPRIVLIB) \ + $(INST_ARCHLIB) $(INSTALLARCHLIB) \ + $(INST_BIN) $(INSTALLBIN) \ + $(INST_SCRIPT) $(INSTALLSCRIPT) \ + $(INST_MAN1DIR) $(INSTALLMAN1DIR) \ + $(INST_MAN3DIR) $(INSTALLMAN3DIR) + @$(WARN_IF_OLD_PACKLIST) \ + $(SITEARCHEXP)/auto/$(FULLEXT) + + +pure_site_install :: + @$(MOD_INSTALL) \ + read $(SITEARCHEXP)/auto/$(FULLEXT)/.packlist \ + write $(INSTALLSITEARCH)/auto/$(FULLEXT)/.packlist \ + $(INST_LIB) $(INSTALLSITELIB) \ + $(INST_ARCHLIB) $(INSTALLSITEARCH) \ + $(INST_BIN) $(INSTALLSITEBIN) \ + $(INST_SCRIPT) $(INSTALLSCRIPT) \ + $(INST_MAN1DIR) $(INSTALLSITEMAN1DIR) \ + $(INST_MAN3DIR) $(INSTALLSITEMAN3DIR) + @$(WARN_IF_OLD_PACKLIST) \ + $(PERL_ARCHLIB)/auto/$(FULLEXT) + +pure_vendor_install :: + @$(MOD_INSTALL) \ + $(INST_LIB) $(INSTALLVENDORLIB) \ + $(INST_ARCHLIB) $(INSTALLVENDORARCH) \ + $(INST_BIN) $(INSTALLVENDORBIN) \ + $(INST_SCRIPT) $(INSTALLSCRIPT) \ + $(INST_MAN1DIR) $(INSTALLVENDORMAN1DIR) \ + $(INST_MAN3DIR) $(INSTALLVENDORMAN3DIR) + +doc_perl_install :: + -@$(MKPATH) $(INSTALLARCHLIB) + -@$(DOC_INSTALL) \ + "Module" "$(NAME)" \ + "installed into" "$(INSTALLPRIVLIB)" \ + LINKTYPE "$(LINKTYPE)" \ + VERSION "$(VERSION)" \ + EXE_FILES "$(EXE_FILES)" \ + >> $(INSTALLARCHLIB)/perllocal.pod + +doc_site_install :: + -@$(MKPATH) $(INSTALLARCHLIB) + -@$(DOC_INSTALL) \ + "Module" "$(NAME)" \ + "installed into" "$(INSTALLSITELIB)" \ + LINKTYPE "$(LINKTYPE)" \ + VERSION "$(VERSION)" \ + EXE_FILES "$(EXE_FILES)" \ + >> $(INSTALLSITEARCH)/perllocal.pod + +doc_vendor_install :: + + +uninstall :: uninstall_from_$(INSTALLDIRS)dirs + +uninstall_from_perldirs :: + @$(UNINSTALL) $(PERL_ARCHLIB)/auto/$(FULLEXT)/.packlist + +uninstall_from_sitedirs :: + @$(UNINSTALL) $(SITEARCHEXP)/auto/$(FULLEXT)/.packlist + + +# --- MakeMaker force section: +# Phony target to force checking subdirectories. +FORCE: + @$(NOOP) + + +# --- MakeMaker perldepend section: + +PERL_HDRS = \ + $(PERL_INC)/EXTERN.h \ + $(PERL_INC)/INTERN.h \ + $(PERL_INC)/XSUB.h \ + $(PERL_INC)/av.h \ + $(PERL_INC)/cc_runtime.h \ + $(PERL_INC)/config.h \ + $(PERL_INC)/cop.h \ + $(PERL_INC)/cv.h \ + $(PERL_INC)/dosish.h \ + $(PERL_INC)/embed.h \ + $(PERL_INC)/embedvar.h \ + $(PERL_INC)/fakethr.h \ + $(PERL_INC)/form.h \ + $(PERL_INC)/gv.h \ + $(PERL_INC)/handy.h \ + $(PERL_INC)/hv.h \ + $(PERL_INC)/intrpvar.h \ + $(PERL_INC)/iperlsys.h \ + $(PERL_INC)/keywords.h \ + $(PERL_INC)/mg.h \ + $(PERL_INC)/nostdio.h \ + $(PERL_INC)/op.h \ + $(PERL_INC)/opcode.h \ + $(PERL_INC)/opnames.h \ + 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Makefile.perl.old + -$(MAKE) -f Makefile.perl.old clean $(DEV_NULL) || $(NOOP) + $(PERLRUN) Makefile.PL + @echo "==> Your Makefile has been rebuilt. <==" + @echo "==> Please rerun the make command. <==" + false + + + +# --- MakeMaker staticmake section: + +# --- MakeMaker makeaperl section --- +MAP_TARGET = perl +FULLPERL = /usr/bin/perl + +$(MAP_TARGET) :: static $(MAKE_APERL_FILE) + $(MAKE) -f $(MAKE_APERL_FILE) $@ + +$(MAKE_APERL_FILE) : $(FIRST_MAKEFILE) + @echo Writing \"$(MAKE_APERL_FILE)\" for this $(MAP_TARGET) + @$(PERLRUNINST) \ + Makefile.PL DIR= \ + MAKEFILE=$(MAKE_APERL_FILE) LINKTYPE=static \ + MAKEAPERL=1 NORECURS=1 CCCDLFLAGS= + + +# --- MakeMaker test section: + +TEST_VERBOSE=0 +TEST_TYPE=test_$(LINKTYPE) +TEST_FILE = test.pl +TEST_FILES = +TESTDB_SW = -d + +testdb :: testdb_$(LINKTYPE) + +test :: $(TEST_TYPE) + +test_dynamic :: pure_all + PERL_DL_NONLAZY=1 $(FULLPERLRUN) "-I$(INST_LIB)" "-I$(INST_ARCHLIB)" $(TEST_FILE) + +testdb_dynamic :: pure_all + PERL_DL_NONLAZY=1 $(FULLPERLRUN) $(TESTDB_SW) "-I$(INST_LIB)" "-I$(INST_ARCHLIB)" $(TEST_FILE) + +test_ : test_dynamic + +test_static :: pure_all $(MAP_TARGET) + PERL_DL_NONLAZY=1 ./$(MAP_TARGET) "-I$(INST_LIB)" "-I$(INST_ARCHLIB)" $(TEST_FILE) + +testdb_static :: pure_all $(MAP_TARGET) + PERL_DL_NONLAZY=1 ./$(MAP_TARGET) $(TESTDB_SW) "-I$(INST_LIB)" "-I$(INST_ARCHLIB)" $(TEST_FILE) + + + +# --- MakeMaker ppd section: +# Creates a PPD (Perl Package Description) for a binary distribution. +ppd: + @$(PERL) -e "print qq{\n\t$(DISTNAME)\n\t\n\tIvo Hofacker <ivo\@tbi.univie.ac.at>\n}" > $(DISTNAME).ppd + @$(PERL) -e "print qq{\t\n}" >> $(DISTNAME).ppd + @$(PERL) -e "print qq{\t\t\n\t\t\n\t\t\n\t\n\n}" >> $(DISTNAME).ppd + +# --- MakeMaker pm_to_blib section: + +pm_to_blib: $(TO_INST_PM) + @$(PERLRUNINST) "-MExtUtils::Install" \ + -e "pm_to_blib({qw{RNA.pm $(INST_LIBDIR)/RNA.pm}},'$(INST_LIB)/auto','$(PM_FILTER)')" + @$(TOUCH) $@ + +# --- MakeMaker selfdocument section: + + +# --- MakeMaker postamble section: + + +# End. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.bs b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.bs new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.i b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.i new file mode 100755 index 00000000..c408b19c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.i @@ -0,0 +1,455 @@ +%module RNA +//%pragma(perl5) modulecode="@EXPORT=qw(fold);" +%pragma(perl5) include="RNA.pod" +%{ +#include "../H/utils.h" +#include "../H/fold_vars.h" +#undef fold +#include "../H/fold.h" +#include "../H/cofold.h" +#include "../H/part_func.h" +#include "../H/PS_dot.h" +#include "../H/inverse.h" +#include "../H/RNAstruct.h" +#include "../H/treedist.h" +#include "../H/stringdist.h" +#include "../H/profiledist.h" +#include "../H/dist_vars.h" +#include "../H/pair_mat.h" +#include "../H/subopt.h" +#include "../H/energy_const.h" +#include "../H/params.h" +%} +// +%include carrays.i +%array_functions(int, intP); +%array_class(int, intArray); +%array_functions(float, floatP); +%array_class(float, floatArray); +%array_functions(double, doubleP); +%array_class(double, doubleArray); +%array_functions(short, shortP); +%include cdata.i + +%constant double VERSION = 0.3; +%include typemaps.i +%typemap(perl5,in) FILE * { + if (SvOK($input)) /* check for undef */ + $1 = PerlIO_findFILE(IoIFP(sv_2io($input))); + else $1 = NULL; +} + +%typemap(python,in) FILE * { + if (PyFile_Check($input)) /* check for undef */ + $1 = PyFile_AsFile($input); + else $1 = NULL; +} + +//%title "Interface to the Vienna RNA library" +//%section "Folding Routines" +//%subsection "Minimum free Energy Folding" + +%rename (fold) my_fold; + +%{ + char *my_fold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = fold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } +%} + +%newobject my_fold; +char *my_fold(char *string, char *constraints = NULL, float *OUTPUT); +%ignore fold; +%include "../H/fold.h" + +%rename (cofold) my_cofold; + +%{ + char *my_cofold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = cofold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } +%} + +%newobject my_cofold; +char *my_cofold(char *string, char *constraints = NULL, float *OUTPUT); +%ignore cofold; +%include "../H/cofold.h" + +//%subsection "Partition function Folding" + +%rename (pf_fold) my_pf_fold; +%{ + char *my_pf_fold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = pf_fold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } +%} + +%newobject my_pf_fold; +char *my_pf_fold(char *string, char *constraints = NULL, float *OUTPUT); + +%ignore pf_fold; +%include "../H/part_func.h" + +%newobject pbacktrack; +extern char *pbacktrack(char *sequence); + +//%subsection "Inverse Folding" + +%rename (inverse_fold) my_inverse_fold; +%{ + char *my_inverse_fold(char *start, const char *target, float *cost) { + char *seq; + int n; + n = strlen(target); + seq = random_string(n, symbolset); + if (start) + strncpy(seq, start, strlen(start)); + *cost = inverse_fold(seq, target); + if (start) + /* for backward compatibility modify start */ + strncpy(start, seq, strlen(start)); + return(seq); + } +%} + +%newobject my_inverse_fold; +char * my_inverse_fold(char *start, const char *target, float *OUTPUT); + +%rename (inverse_pf_fold) my_inverse_pf_fold; +%{ + char *my_inverse_pf_fold(char *start, const char *target, float *cost) { + char *seq; + int n; + n = strlen(target); + seq = random_string(n, symbolset); + if (start) strncpy(seq, start, n); + *cost = inverse_pf_fold(seq, target); + if (start) + /* for backward compatibility modify start */ + strncpy(start, seq, strlen(start)); + return(seq); + } +%} + +%newobject my_inverse_pf_fold; +char * my_inverse_pf_fold(char *start, const char *target, float *OUTPUT); + +%ignore inverse_fold; +%ignore inverse_pf_fold; +%include "../H/inverse.h" + +//%subsection "Global Variables to Modify Folding" +//extern double *pr; /* base pairing prob. matrix */ +%include "../H/fold_vars.h" +%extend bondT { + bondT *get(int i) { + return self+i; + } +} + +//%include "../H/subopt.h" +// from subopt.h + +typedef struct { + float energy; /* energy of structure */ + char *structure; +} SOLUTION; + +%newobject subopt; +extern SOLUTION *subopt (char *seq, char *constraint, int delta, FILE *fp=NULL); + +extern int subopt_sorted; /* sort output by energy */ +%extend SOLUTION { + SOLUTION *get(int i) { +// static int size=-1; +// if (size<0) { +// SOLUTION *s; +// for (s=self; s->structure; s++); +// size= (int) (s-self); +// } +// if (i>=size) { +// warn("value out of range"); +// return NULL; +// } + return self+i; + } + + int size() { + SOLUTION *s; + for (s=self; s->structure; s++); + return (int)(s-self); + } + + ~SOLUTION() { + SOLUTION *s; + for (s=self; s->structure; s++) free(s->structure); + free(self); + } +} +%{ +double get_pr(int i, int j) { + int ii; + if (i>j) {ii=i; i=j; j=ii;} + return pr[iindx[i]-j]; +} +%} +double get_pr(int i, int j); +/* Get probability of pair i.j from the pr array */ + +//%section "Parsing and Comparing Structures" +// from RNAstruct.h + +%newobject b2HIT; +%newobject b2C; +%newobject b2Shapiro; +%newobject add_root; +%newobject expand_Shapiro; +%newobject expand_Full; +%newobject unexpand_Full; +%newobject unweight; +char *b2HIT(char *structure); // Full -> HIT [incl. root] +char *b2C(char *structure); // Full -> Coarse [incl. root] +char *b2Shapiro(char *structure); // Full -> weighted Shapiro [i.r] +char *add_root(char *); // {Tree} -> ({Tree}R) +char *expand_Shapiro(char *coarse); // add S for stacks to coarse struct +char *expand_Full(char *structure); // Full -> FFull +char *unexpand_Full(char *ffull); // FFull -> Full +char *unweight(char *wcoarse); // remove weights from coarse struct +void unexpand_aligned_F(char *align[2]); +void parse_structure(char *structure); // make structure statistics +int loop_size[1000]; // loop sizes of a structure +int helix_size[1000]; // helix sizes of a structure +int loop_degree[1000]; // loop degrees of a structure +int loops; // n of loops and stacks +int unpaired, pairs; // n of unpaired digits and pairs + +%include "../H/treedist.h" +%include "../H/stringdist.h" +%newobject Make_bp_profile; +%include "../H/profiledist.h" +// from dist_vars.h +int edit_backtrack; /* set to 1 if you want backtracking */ +char *aligned_line[2]; /* containes alignment after backtracking */ +int cost_matrix; /* 0 usual costs (default), 1 Shapiro's costs */ + +//%section "Utilities" +%newobject space; +%newobject time_stamp; +%newobject random_string; +%newobject get_line; +%newobject pack_structure; +%newobject unpack_structure; +%newobject make_pair_table; + +%include "../H/utils.h" + +// from read_epars.c +extern void read_parameter_file(char *fname); +/* read energy parameters from file */ +extern void write_parameter_file(char *fname); +/* write energy parameters to file */ + +// this doesn't work currently +%inline %{ +void *deref_any(void **ptr, int index) { + /* dereference arbitray pointer */ + return (void *) ptr[index]; +} +%} + +// from params.h + +extern paramT *scale_parameters(void); +extern paramT *copy_parameters(void); +extern paramT *set_parameters(paramT *dest); +%{ +char *get_aligned_line(int i) { + i = i % 2; + return aligned_line[i]; +} +%} + +char *get_aligned_line(int); + + + +//%include ptr2array.i + + + +%inline %{ + short *make_loop_index(const char *structure) { + /* number each position by which loop it belongs to (positions start at 0) */ + int i,j,hx,l,nl; + int length; + short *stack; + short *loop; + length = strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + loop = (short *) space(sizeof(short)*(length+2)); + hx=l=nl=0; + for (i=0; i0) + l = loop[stack[hx-1]]; /* index of enclosing loop */ + else l=0; /* external loop has index 0 */ + if (hx<0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in make_pair_table"); + } + } + } + free(stack); + return loop; + } +%} + +%inline %{ +float energy_of_move(const char *string, char *structure, int mi, int mj) { + extern int energy_of_struct_pt(const char *string, short * ptable, + short *s, short *s1); +#define ILLEGAL 999.; + int i,j,hx,l,nl; + int length; + short *stack, *table, *loop; + short *S, *S1; + int energy; + + if (mj<0) { + if ((structure[-mi]!='(') || (structure[-mj]!=')')) + return 1001; /* illegal delete pair */ + } else + if ((structure[mi]!='.') || (structure[mj]!='.')) + return 1002; /* illegal add pair */ + + /* make the pair table and loop index l*/ + length = strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + loop = (short *) space(sizeof(short)*(length+2)); + table = (short *) space(sizeof(short)*(length+2)); + table[0] = length; + hx=l=nl=0; + for (i=1; i<=length; i++) { + if (structure[i-1] == '(') { + nl++; l=nl; + stack[hx++]=i; + } + loop[i]=l; + if (structure[i-1] ==')') { + j=stack[--hx]; + if (hx>0) + l = loop[stack[hx-1]]; /* index of enclosing loop */ + else l=0; /* external loop has index 0 */ + if (hx<0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in energy_of_move"); + } + table[i]=j; + table[j]=i; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in energy_of_move"); + } + + if (loop[abs(mi)+1] != loop[abs(mj)+1]) { /* not in same loop => illegal */ + free(stack); + free(loop); + free(table); + return 1003.; + } + + /* if we get here the move is legal */ + if (mj<0) { /* delete pair */ + structure[-mi] = '.'; + structure[-mj] = '.'; + table[-mi+1] = table[-mj+1] = 0; + } else { /* insert pair */ + structure[mi] = '('; + structure[mj] = ')'; + table[mi+1] = mj+1; + table[mj+1] = mi+1; + } + + S = (short *) space(sizeof(short)*(length+1)); + S[0] = length; + for (i=1; i<=length; i++) { + char *pos; + pos = strchr(Law_and_Order, string[i-1]); + if (pos==NULL) S[i]=0; + else S[i] = pos-Law_and_Order; + } + + energy = energy_of_struct_pt(string, table, S, S); + + free(S); + free(stack); + free(loop); + free(table); + return (float) energy/100.; +} +%} + +%init %{ +/* work around segfault when script tries to free symbolset */ + +symbolset = (char *) space(21); +strcpy(symbolset, "AUGC"); + +%} + + +// Convert Perl array reference int a char ** +// not needed curently +//%typemap(perl5,in) char ** { +// AV *tempav; +// I32 len; +// int i; +// SV **tv; +// if (!SvROK($input)) croak("$input is not a reference."); +// if (SvTYPE(SvRV($input)) != SVt_PVAV) croak("$input is not an array."); +// tempav = (AV*)SvRV($input); +// len = av_len(tempav); +// $1 = (char **) malloc((len+2)*sizeof(char *)); +// for (i = 0; i <= len; i++) { +// tv = av_fetch(tempav, i, 0); +// $1[i] = (char *) SvPV(*tv,PL_na); +// } +// $1[i] = 0; +//} +// This cleans up our char ** array after the function call +//%typemap(perl5,freearg) char ** { +// free($1); +//} +%include "../H/PS_dot.h" diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.pm b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.pm new file mode 100755 index 00000000..a4cb55d5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA.pm @@ -0,0 +1,1075 @@ +# This file was automatically generated by SWIG +package RNA; +require Exporter; +require DynaLoader; +@ISA = qw(Exporter DynaLoader); +package RNAc; +bootstrap RNA; +package RNA; +@EXPORT = qw( ); +=head1 NAME + +RNA - interface to the Vienna RNA library (libRNA.a) +Version 0.3 + +=head1 SYNOPSIS + + use RNA; + $seq = "CGCAGGGAUACCCGCG"; + ($struct, $mfe) = RNA::fold($seq); #predict mfe structure of $seq + RNA::PS_rna_plot($seq, $struct, "rna.ps"); # write PS plot to rna.ps + $F = RNA::pf_fold($seq); # compute partition function and pair pobabilities + RNA::PS_dot_plot($seq, "dot.ps"); # write dot plot to dot.ps + ... + +=head1 DESCRIPTION + +The RNA.pm package gives access to almost all functions in the libRNA.a +library of the Vienna RNA PACKAGE. The Perl wrapper is generated using +SWIG http://www.swig.org/ with relatively little manual intervention. +For each C function in the library the perl package provides a function +of the same name and calling convention (with few exceptions). For +detailed information you should therefore also consult the documentation +of the library (info RNAlib). + +Note that in general C arrays are wrapped into opaque objects that can +only be accessed via helper functions. SWIG provides a couple of general +purpose helper functions, see the section at the end of this file. C +structures are wrapped into Perl objects using SWIG's shadow class +mechanism, resulting in a tied hash with keys named after the structure +members. + +For the interrested reader we list for each scalar type of the +corepsonding C variable in brackets, and point out the header files +containing the C declaration. + +=head2 Folding Routines + +Minimum free Energy Folding (from fold.h) + +=over 4 + +=item fold SEQUENCE + +=item fold SEQUENCE, CONSTRAINTS + +computes the minimum free energy structure of the string SEQUENCE and returns +the predicted structure and energy, e.g. + + ($structure, $mfe) = RNA::fold("UGUGUCGAUGUGCUAU"); + +If a second argument is supplied and +L<$fold_constrained|/$fold_constrained>==1 the CONSTRAINTS string is +used to specify constraints on the predicted structure. The +characters '|', 'x', '<', '>' mark bases that are paired, unpaired, +paired upstream, or downstream, respectively; matching brackets "( )" +denote base pairs, dots '.' are used for unconstrained bases. + +In the two argument version the CONSTRAINTS string is modified and holds the +predicted structure upon return. This is done for backwards compatibility only, +and might change in future versions. + +=item energy_of_struct SEQUENCE, STRUCTURE + +returns the energy of SEQUENCE on STRUCTURE (in kcal/mol). The string structure +must hold a valid secondary structure in bracket notation. + +=item update_fold_params + +recalculate the pair matrix and energy parameters after a change in folding +parameters. In many cases (such as changes to +L<$temperature|/$temperature>) the fold() routine will call +update_fold_params automatically when necessary. + +=item free_arrays + +frees memory allocated internally when calling L. + +=back + +Partition function Folding (from part_func.h) + +=over 4 + +=item pf_fold SEQUENCE + +=item pf_fold SEQUENCE, CONSTRAINTS + +calculates the partition function over all possible secondary +structures and the matrix of pair probabilities for SEQUENCE and +returns a two element list consisting of a string summarizing possible +structures. See below on how to access the pair probability matrix. As +with L the second argument can be used to specify folding +constraints. Constraints are implemented by excluding base pairings +that contradict the constraint, but without bonus +energies. Constraints of type '|' (paired base) are ignored. In the +two argument version CONSTRAINTS is modified to contain the structure +string on return (obsolete feature, for backwards compatibility only) + +=item get_pr I, J + +After calling C the global C variable C points to the +computed pair probabilities. Perl access to the C is facilitated by +the C helper function that looks up and returns the +probability of the pair (I,J). + +=item free_pf_arrays + +frees memory allocated for pf_fold + +=item update_pf_params LENGTH + +recalculate energy parameters for pf_fold. In most cases (such as +simple changes to L<$temperature|/$temperature>) C +will take appropriate action automatically. + +=back + +Suboptimal Folding (from subopt.h) + +=over 4 + +=item subopt SEQUENCE, CONSTRAINTS, DELTA + +=item subopt SEQUENCE, CONSTRAINTS, DELTA, FILEHANDLE + +compute all structures of SEQUENCE within DELTA*0.01 kcal/mol of the +optimum. If specified, results are written to FILEHANDLE and nothing +is returned. Else, the C function returnes a list of C structs of type +SOLUTION. The list is wrapped by SWIG as a perl object that can be +accesses as follows: + + $solution = subopt($seq, undef, 500); + for (0..$solution->size()-1) { + printf "%s %6.2f\n", $solution->get($_)->{structure}, + $solution->get($_)->{energy}; + } + +=back + +Inverse Folding (from inverse.h) + +=over 4 + +=item inverse_fold START, TARGET + +find a sequence that folds into structure TARGET, by optimizing the +sequence until its mfe structure (as returned by L) is +TARGET. Startpoint of the optimization is the sequence START. Returns +a list containing the sequence found and the final value of the cost +function, i.e. 0 if the search was successful. A random start sequence +can be generated using L. + +=item inverse_pf_fold START, TARGET + +optimizes a sequence (beginning with START) by maximising the +frequency of the structure TARGET in the thermodynamic ensemble +of structures. Returns a list containing the optimized sequence and +the final value of the cost function. The cost function is given by +C, i.e.C<-RT*log(p(TARGET))> + +=item $final_cost [float] + +holds the value of the cost function where the optimization in +C should stop. For values <=0 the optimization will +only terminate at a local optimimum (which might take very long to reach). + +=item $symbolset [char *] + +the string symbolset holds the allowed characters to be used by +C and C, the default alphabet is "AUGC" + + +=item $give_up [int] + +If non-zero stop optimization when its clear that no exact solution +can be found. Else continue and eventually return an approximate +solution. Default 0. + +=back + +Global Variables to Modify Folding (from fold_vars.h) + +=over 4 + +=item $noGU [int] + +Do not allow GU pairs to form, default 0. + +=item $no_closingGU [int] + +allow GU only inside stacks, default 0. + +=item $tetra_loop [int] + +Fold with specially stable 4-loops, default 1. + +=item $energy_set [int] + +0 = BP; 1=any mit GC; 2=any mit AU-parameter, default 0. + +=item $dangles [int] + +How to compute dangling ends. 0: no dangling end energies, 1: "normal" +dangling ends (default), 2: simplified dangling ends, 3: "normal" + +co-axial stacking. Note that L treats cases 1 and 3 +as 2. The same holds for the main computation in L, +however subopt will re-evalute energies using +L for cases 1 and 3. See the more +detailed discussion in RNAlib.texinfo. + +=item $nonstandards [char *] + +contains allowed non standard bases, default empty string "" + +=item $temperature [double] + +temperature in degrees Celsius for rescaling parameters, default 37C. + +=item $logML [int] + +use logarithmic multiloop energy function in +L, default 0. + +=item $noLonelyPairs [int] + +consider only structures without isolated base pairs (helices of length 1). +For L only eliminates pairs +that can B occur as isolated pairs. Default 0. + +=item $base_pair [struct bond *] + +list of base pairs from last call to L. Better use +the structure string returned by L. + +=item $pf_scale [double] + +scaling factor used by L to avoid overflows. Should +be set to exp(-F/(RT*length)) where F is a guess for the ensmble free +energy (e.g. use the mfe). + + +=item $fold_constrained [int] + +apply constraints in the folding algorithms, default 0. + +=item $do_backtrack [int] + +If 0 do not compute the pair probabilities in L +(only the partition function). Default 1. + +=item $backtrack_type [char] + +usually 'F'; 'C' require (1,N) to be bonded; 'M' backtrack as if the +sequence was part of a multi loop. Used by L + +=item $pr [double *] + +the base pairing prob. matrix computed by L. + +=item $iindx [int *] + +Array of indices for moving withing the C array. Better use +L. + + +=back + +=head2 Parsing and Comparing Structures + +from RNAstruct.h: these functions convert between strings +representating secondary structures with various levels of coarse +graining. See the documentation of the C library for details + +=over 4 + +=item b2HIT STRUCTURE + +Full -> HIT [incl. root] + +=item b2C STRUCTURE + +Full -> Coarse [incl. root] + +=item b2Shapiro STRUCTURE + +Full -> weighted Shapiro [i.r.] + +=item add_root STRUCTURE + +{Tree} -> ({Tree}R) + +=item expand_Shapiro COARSE + +add S for stacks to coarse struct + +=item expand_Full STRUCTURE + +Full -> FFull + +=item unexpand_Full FSTRUCTURE + +FFull -> Full + +=item unweight WCOARSE + +remove weights from coarse struct + +=item unexpand_aligned_F ALIGN + + + +=item parse_structure STRUCTURE + +computes structure statistics, and fills the following global variables: + +$loops [int] number of loops (and stacks) +$unpaired [int] number of unpaired positions +$pairs [int] number of paired positions +$loop_size[int *] holds all loop sizes +$loop_degree[int *] holds all loop degrees +$helix_size[int *] holds all helix lengths + +=back + +from treedist.h: routines for computing tree-edit distances between structures + +=over 4 + +=item make_tree STRUCTURE + +make input for tree_edit_distance (a Tree * pointer). + +=item tree_edit_distance T1, T2 + +compare to structures using tree editing. C, C must have been +created using C + +=item print_tree T + +mainly for debugging + +=item free_tree T + +free space allocated by make_tree + +=back + +from stringdist.h routines to compute structure distances via string-editing + +=over 4 + +=item Make_swString STRUCTURE + +[ returns swString * ] +make input for string_edit_distance + +=item string_edit_distance S1, S2 + +[ returns float ] +compare to structures using string alignment. C, C should be +created using C + +=back + +from profiledist + +=over + +=item Make_bp_profile LENGTH + +[ returns (float *) ] +condense pair probability matrix C into a vector containing +probabilities for upstream paired, downstream paired and +unpaired. This resulting probability profile is used as input for +profile_edit_distance + +=item profile_edit_distance T1, T2 + +[ returns float ] +align two probability profiles produced by C + +=item print_bppm T + +[ returns void ] +print string representation of probability profile + +=item free_profile T + +[ returns void ] +free space allocated in Make_bp_profile + +=back + +Global variables for computing structure distances + +=over 4 + +=item $edit_backtrack [int] + +set to 1 if you want backtracking + +=item $aligned_line [(char *)[2]] + +containes alignmed structures after computing structure distance with +C + +=item $cost_matrix [int] + +0 usual costs (default), 1 Shapiro's costs + +=back + +=head2 Utilities (from utils.h) + +=over 4 + +=item space SIZE + +allocate memory from C. Usually not needed in Perl + +=item nrerror MESSGAE + +die with error message. Better use Perl's C + +=item $xsubi [unsigned short[3]] + +libRNA uses the rand48 48bit random number generator if available, the +current random number is always stored in $xsubi. + +=item init_rand + +initialize the $xsubi random number from current time + +=item urn + +returns a random number between 0 and 1 using the random number +generator from the RNA library. + +=item int_urn FROM, TO + +returns random integer in the range [FROM..TO] + +=item time_stamp + +current date in a string. In perl you might as well use C + +=item random_string LENGTH, SYMBOLS + +returns a string of length LENGTH using characters from the string +SYMBOLS + +=item hamming S1, S2 + +calculate hamming distance of the strings C and C. + + +=item pack_structure STRUCTURE + +pack secondary structure, using a 5:1 compression via 3 +encoding. Returns the packed string. + +=item unpack_structure PACKED + +unpacks a secondary structure packed with pack_structure + +=item make_pair_table STRUCTURE + +returns a pair table as a newly allocated (short *) C array, such +that: table[i]=j if (i.j) pair or 0 if i is unpaired, table[0] +contains the length of the structure. + +=item bp_distance STRUCTURE1, STRUCTURE2 + +returns the base pair distance of the two STRUCTURES. dist = {number +of base pairs in one structure but not in the other} same as edit +distance with open-pair close-pair as move-set + +=back + +from PS_plot.h + +=over 4 + +=item PS_rna_plot SEQUENCE, STRUCTURE, FILENAME + +write PostScript drawing of structure to FILENAME. Returns 1 on +sucess, 0 else. + +=item PS_rna_plot_a SEQUENCE, STRUCTURE, FILENAME, PRE, POST + +write PostScript drawing of structure to FILENAME. The strings PRE and +POST contain PostScript code that is included verbatim in the plot just +before (after) the data. Returns 1 on sucess, 0 else. + +=item gmlRNA SEQUENCE, STRUCTURE, FILENAME, OPTION + +write structure drawing in gml (Graph Meta Language) to +FILENAME. OPTION should be a single character. If uppercase the gml +output will include the SEQUENCE as node labels. IF OPTION equal 'x' +or 'X' write graph with coordinates (else only connectivity +information). Returns 1 on sucess, 0 else. + +=item ssv_rna_plot SEQUENCE, STRUCTURE, SSFILE + +write structure drfawing as coord file for SStructView Returns 1 on +sucess, 0 else. + +=item xrna_plot SEQUENCE, STRUCTURE, SSFILE + +write structure drawing as ".ss" file for further editing in XRNA. +Returns 1 on sucess, 0 else. + +=item PS_dot_plot SEQUENCE, FILENAME + +write a PostScript dot plot of the pair probability matix to +FILENAME. Returns 1 on sucess, 0 else. + +=item $rna_plot_type [int] + +Select layout algorithm for structure drawings. Currently available +0= simple coordinates, 1= naview, default 1. + +=back + +from read_epars.c + +=over 4 + +=item read_parameter_file FILENAME + +read energy parameters from FILENAME + +=item write_parameter_file FILENAME + +write energy parameters to FILENAME + +=back + +=head2 SWIG helper functions + +The package includes generic helper functions to access C arrays +of type C, C and C, such as: + +=over 4 + +=item intP_getitem POINTER, INDEX + +return the element INDEX from the array + +=item intP_setitem POINTER, INDEX, VALUE + +set element INDEX to VALUE + +=item new_intP NELEM + +allocate a new C array of integers with NELEM elements and return the pointer + +=item delete_intP POINTER + +deletes the C array by calling free() + +=back + +substituting C with C or C gives the corresponding +functions for arrays of float or double. You need to know the correct C +type however, and the function work only for arrays of simple types. + +On the lowest level the C function gives direct access to any data +in the form of a Perl string. + +=over + +=item cdata POINTER, SIZE + +copies SIZE bytes at POINTER to a Perl string (with binary data) + +=item memmove POINTER, STRING + +copies the (binary) string STRING to the memory location pointed to by +POINTER. + + +=back + +In combination with Perl's C this provides a generic way to convert +C data structures to Perl. E.g. + + RNA::parse_structure($structure); # fills the $RNA::loop_degree array + @ldegrees = unpack "I*", RNA::cdata($RNA::loop_degree, ($RNA::loops+1)*4); + +Warning: using these functions with wrong arguments will corrupt your +memory and lead to a segmentation fault. + +=head1 AUTHOR + +Ivo L. Hofacker + +=cut + +# ---------- BASE METHODS ------------- + +package RNA; + +sub TIEHASH { + my ($classname,$obj) = @_; + return bless $obj, $classname; +} + +sub CLEAR { } + +sub FIRSTKEY { } + +sub NEXTKEY { } + +sub FETCH { + my ($self,$field) = @_; + my $member_func = "swig_${field}_get"; + $self->$member_func(); +} + +sub STORE { + my ($self,$field,$newval) = @_; + my $member_func = "swig_${field}_set"; + $self->$member_func($newval); +} + +sub this { + my $ptr = shift; + return tied(%$ptr); +} + + +# ------- FUNCTION WRAPPERS -------- + +package RNA; + +*new_intP = *RNAc::new_intP; +*delete_intP = *RNAc::delete_intP; +*intP_getitem = *RNAc::intP_getitem; +*intP_setitem = *RNAc::intP_setitem; +*new_floatP = *RNAc::new_floatP; +*delete_floatP = *RNAc::delete_floatP; +*floatP_getitem = *RNAc::floatP_getitem; +*floatP_setitem = *RNAc::floatP_setitem; +*new_doubleP = *RNAc::new_doubleP; +*delete_doubleP = *RNAc::delete_doubleP; +*doubleP_getitem = *RNAc::doubleP_getitem; +*doubleP_setitem = *RNAc::doubleP_setitem; +*new_shortP = *RNAc::new_shortP; +*delete_shortP = *RNAc::delete_shortP; +*shortP_getitem = *RNAc::shortP_getitem; +*shortP_setitem = *RNAc::shortP_setitem; +*cdata = *RNAc::cdata; +*memmove = *RNAc::memmove; +*fold = *RNAc::fold; +*energy_of_struct = *RNAc::energy_of_struct; +*free_arrays = *RNAc::free_arrays; +*initialize_fold = *RNAc::initialize_fold; +*update_fold_params = *RNAc::update_fold_params; +*cofold = *RNAc::cofold; +*free_co_arrays = *RNAc::free_co_arrays; +*initialize_cofold = *RNAc::initialize_cofold; +*update_cofold_params = *RNAc::update_cofold_params; +*pf_fold = *RNAc::pf_fold; +*init_pf_fold = *RNAc::init_pf_fold; +*free_pf_arrays = *RNAc::free_pf_arrays; +*update_pf_params = *RNAc::update_pf_params; +*bppm_symbol = *RNAc::bppm_symbol; +*mean_bp_dist = *RNAc::mean_bp_dist; +*pbacktrack = *RNAc::pbacktrack; +*inverse_fold = *RNAc::inverse_fold; +*inverse_pf_fold = *RNAc::inverse_pf_fold; +*option_string = *RNAc::option_string; +*subopt = *RNAc::subopt; +*get_pr = *RNAc::get_pr; +*b2HIT = *RNAc::b2HIT; +*b2C = *RNAc::b2C; +*b2Shapiro = *RNAc::b2Shapiro; +*add_root = *RNAc::add_root; +*expand_Shapiro = *RNAc::expand_Shapiro; +*expand_Full = *RNAc::expand_Full; +*unexpand_Full = *RNAc::unexpand_Full; +*unweight = *RNAc::unweight; +*unexpand_aligned_F = *RNAc::unexpand_aligned_F; +*parse_structure = *RNAc::parse_structure; +*make_tree = *RNAc::make_tree; +*tree_edit_distance = *RNAc::tree_edit_distance; +*print_tree = *RNAc::print_tree; +*free_tree = *RNAc::free_tree; +*Make_swString = *RNAc::Make_swString; +*string_edit_distance = *RNAc::string_edit_distance; +*Make_bp_profile = *RNAc::Make_bp_profile; +*profile_edit_distance = *RNAc::profile_edit_distance; +*print_bppm = *RNAc::print_bppm; +*free_profile = *RNAc::free_profile; +*space = *RNAc::space; +*xrealloc = *RNAc::xrealloc; +*nrerror = *RNAc::nrerror; +*init_rand = *RNAc::init_rand; +*urn = *RNAc::urn; +*int_urn = *RNAc::int_urn; +*filecopy = *RNAc::filecopy; +*time_stamp = *RNAc::time_stamp; +*random_string = *RNAc::random_string; +*hamming = *RNAc::hamming; +*get_line = *RNAc::get_line; +*pack_structure = *RNAc::pack_structure; +*unpack_structure = *RNAc::unpack_structure; +*make_pair_table = *RNAc::make_pair_table; +*bp_distance = *RNAc::bp_distance; +*read_parameter_file = *RNAc::read_parameter_file; +*write_parameter_file = *RNAc::write_parameter_file; +*deref_any = *RNAc::deref_any; +*scale_parameters = *RNAc::scale_parameters; +*copy_parameters = *RNAc::copy_parameters; +*set_parameters = *RNAc::set_parameters; +*get_aligned_line = *RNAc::get_aligned_line; +*make_loop_index = *RNAc::make_loop_index; +*energy_of_move = *RNAc::energy_of_move; +*PS_rna_plot = *RNAc::PS_rna_plot; +*PS_rna_plot_a = *RNAc::PS_rna_plot_a; +*gmlRNA = *RNAc::gmlRNA; +*ssv_rna_plot = *RNAc::ssv_rna_plot; +*svg_rna_plot = *RNAc::svg_rna_plot; +*xrna_plot = *RNAc::xrna_plot; +*PS_dot_plot = *RNAc::PS_dot_plot; +*PS_color_dot_plot = *RNAc::PS_color_dot_plot; +*PS_dot_plot_list = *RNAc::PS_dot_plot_list; + +############# Class : RNA::intArray ############## + +package RNA::intArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_intArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_intArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::intArray_getitem; +*setitem = *RNAc::intArray_setitem; +*cast = *RNAc::intArray_cast; +*frompointer = *RNAc::intArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::floatArray ############## + +package RNA::floatArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_floatArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_floatArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::floatArray_getitem; +*setitem = *RNAc::floatArray_setitem; +*cast = *RNAc::floatArray_cast; +*frompointer = *RNAc::floatArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::doubleArray ############## + +package RNA::doubleArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_doubleArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_doubleArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::doubleArray_getitem; +*setitem = *RNAc::doubleArray_setitem; +*cast = *RNAc::doubleArray_cast; +*frompointer = *RNAc::doubleArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::bondT ############## + +package RNA::bondT; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::bondT_i_get; +*swig_i_set = *RNAc::bondT_i_set; +*swig_j_get = *RNAc::bondT_j_get; +*swig_j_set = *RNAc::bondT_j_set; +*get = *RNAc::bondT_get; +sub new { + my $pkg = shift; + my $self = RNAc::new_bondT(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_bondT($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::SOLUTION ############## + +package RNA::SOLUTION; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_energy_get = *RNAc::SOLUTION_energy_get; +*swig_energy_set = *RNAc::SOLUTION_energy_set; +*swig_structure_get = *RNAc::SOLUTION_structure_get; +*swig_structure_set = *RNAc::SOLUTION_structure_set; +*get = *RNAc::SOLUTION_get; +*size = *RNAc::SOLUTION_size; +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_SOLUTION($self); + delete $OWNER{$self}; + } +} + +sub new { + my $pkg = shift; + my $self = RNAc::new_SOLUTION(@_); + bless $self, $pkg if defined($self); +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::cpair ############## + +package RNA::cpair; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::cpair_i_get; +*swig_i_set = *RNAc::cpair_i_set; +*swig_j_get = *RNAc::cpair_j_get; +*swig_j_set = *RNAc::cpair_j_set; +*swig_mfe_get = *RNAc::cpair_mfe_get; +*swig_mfe_set = *RNAc::cpair_mfe_set; +*swig_p_get = *RNAc::cpair_p_get; +*swig_p_set = *RNAc::cpair_p_set; +*swig_hue_get = *RNAc::cpair_hue_get; +*swig_hue_set = *RNAc::cpair_hue_set; +*swig_sat_get = *RNAc::cpair_sat_get; +*swig_sat_set = *RNAc::cpair_sat_set; +sub new { + my $pkg = shift; + my $self = RNAc::new_cpair(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_cpair($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::plist ############## + +package RNA::plist; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::plist_i_get; +*swig_i_set = *RNAc::plist_i_set; +*swig_j_get = *RNAc::plist_j_get; +*swig_j_set = *RNAc::plist_j_set; +*swig_p_get = *RNAc::plist_p_get; +*swig_p_set = *RNAc::plist_p_set; +sub new { + my $pkg = shift; + my $self = RNAc::new_plist(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_plist($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +# ------- VARIABLE STUBS -------- + +package RNA; + +*VERSION = *RNAc::VERSION; +*symbolset = *RNAc::symbolset; +*final_cost = *RNAc::final_cost; +*give_up = *RNAc::give_up; +*noGU = *RNAc::noGU; +*no_closingGU = *RNAc::no_closingGU; +*tetra_loop = *RNAc::tetra_loop; +*energy_set = *RNAc::energy_set; +*dangles = *RNAc::dangles; +*nonstandards = *RNAc::nonstandards; +*temperature = *RNAc::temperature; +*james_rule = *RNAc::james_rule; +*logML = *RNAc::logML; +*cut_point = *RNAc::cut_point; + +my %__base_pair_hash; +tie %__base_pair_hash,"RNA::bondT", $RNAc::base_pair; +$base_pair= \%__base_pair_hash; +bless $base_pair, RNA::bondT; +*pr = *RNAc::pr; +*iindx = *RNAc::iindx; +*pf_scale = *RNAc::pf_scale; +*fold_constrained = *RNAc::fold_constrained; +*do_backtrack = *RNAc::do_backtrack; +*noLonelyPairs = *RNAc::noLonelyPairs; +*backtrack_type = *RNAc::backtrack_type; +*subopt_sorted = *RNAc::subopt_sorted; +*loop_size = *RNAc::loop_size; +*helix_size = *RNAc::helix_size; +*loop_degree = *RNAc::loop_degree; +*loops = *RNAc::loops; +*unpaired = *RNAc::unpaired; +*pairs = *RNAc::pairs; +*edit_backtrack = *RNAc::edit_backtrack; +*aligned_line = *RNAc::aligned_line; +*cost_matrix = *RNAc::cost_matrix; +*xsubi = *RNAc::xsubi; +*rna_plot_type = *RNAc::rna_plot_type; +1; diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA_wrap.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA_wrap.c new file mode 100755 index 00000000..6aba3c29 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA_wrap.c @@ -0,0 +1,6502 @@ +/* ---------------------------------------------------------------------------- + * This file was automatically generated by SWIG (http://www.swig.org). + * Version 1.3.24 + * + * This file is not intended to be easily readable and contains a number of + * coding conventions designed to improve portability and efficiency. Do not make + * changes to this file unless you know what you are doing--modify the SWIG + * interface file instead. + * ----------------------------------------------------------------------------- */ + + +#ifndef SWIG_TEMPLATE_DISAMBIGUATOR +# if defined(__SUNPRO_CC) +# define SWIG_TEMPLATE_DISAMBIGUATOR template +# else +# define SWIG_TEMPLATE_DISAMBIGUATOR +# endif +#endif + +/*********************************************************************** + * swigrun.swg + * + * This file contains generic CAPI SWIG runtime support for pointer + * type checking. + * + ************************************************************************/ + +/* This should only be incremented when either the layout of swig_type_info changes, + or for whatever reason, the runtime changes incompatibly */ +#define SWIG_RUNTIME_VERSION "1" + +/* define SWIG_TYPE_TABLE_NAME as "SWIG_TYPE_TABLE" */ +#ifdef SWIG_TYPE_TABLE +#define SWIG_QUOTE_STRING(x) #x +#define SWIG_EXPAND_AND_QUOTE_STRING(x) SWIG_QUOTE_STRING(x) +#define SWIG_TYPE_TABLE_NAME SWIG_EXPAND_AND_QUOTE_STRING(SWIG_TYPE_TABLE) +#else +#define SWIG_TYPE_TABLE_NAME +#endif + +#include + +#ifndef SWIGINLINE +#if defined(__cplusplus) || (defined(__GNUC__) && !defined(__STRICT_ANSI__)) +# define SWIGINLINE inline +#else +# define SWIGINLINE +#endif +#endif + +/* + You can use the SWIGRUNTIME and SWIGRUNTIMEINLINE macros for + creating a static or dynamic library from the swig runtime code. + In 99.9% of the cases, swig just needs to declare them as 'static'. + + But only do this if is strictly necessary, ie, if you have problems + with your compiler or so. +*/ +#ifndef SWIGRUNTIME +#define SWIGRUNTIME static +#endif +#ifndef SWIGRUNTIMEINLINE +#define SWIGRUNTIMEINLINE SWIGRUNTIME SWIGINLINE +#endif + +#ifdef __cplusplus +extern "C" { +#endif + +typedef void *(*swig_converter_func)(void *); +typedef struct swig_type_info *(*swig_dycast_func)(void **); + +typedef struct swig_type_info { + const char *name; + swig_converter_func converter; + const char *str; + void *clientdata; + swig_dycast_func dcast; + struct swig_type_info *next; + struct swig_type_info *prev; +} swig_type_info; + +/* + Compare two type names skipping the space characters, therefore + "char*" == "char *" and "Class" == "Class", etc. + + Return 0 when the two name types are equivalent, as in + strncmp, but skipping ' '. +*/ +SWIGRUNTIME int +SWIG_TypeNameComp(const char *f1, const char *l1, + const char *f2, const char *l2) { + for (;(f1 != l1) && (f2 != l2); ++f1, ++f2) { + while ((*f1 == ' ') && (f1 != l1)) ++f1; + while ((*f2 == ' ') && (f2 != l2)) ++f2; + if (*f1 != *f2) return *f1 - *f2; + } + return (l1 - f1) - (l2 - f2); +} + +/* + Check type equivalence in a name list like ||... +*/ +SWIGRUNTIME int +SWIG_TypeEquiv(const char *nb, const char *tb) { + int equiv = 0; + const char* te = tb + strlen(tb); + const char* ne = nb; + while (!equiv && *ne) { + for (nb = ne; *ne; ++ne) { + if (*ne == '|') break; + } + equiv = SWIG_TypeNameComp(nb, ne, tb, te) == 0; + if (*ne) ++ne; + } + return equiv; +} + +/* + Register a type mapping with the type-checking +*/ +SWIGRUNTIME swig_type_info * +SWIG_TypeRegisterTL(swig_type_info **tl, swig_type_info *ti) { + swig_type_info *tc, *head, *ret, *next; + /* Check to see if this type has already been registered */ + tc = *tl; + while (tc) { + /* check simple type equivalence */ + int typeequiv = (strcmp(tc->name, ti->name) == 0); + /* check full type equivalence, resolving typedefs */ + if (!typeequiv) { + /* only if tc is not a typedef (no '|' on it) */ + if (tc->str && ti->str && !strstr(tc->str,"|")) { + typeequiv = SWIG_TypeEquiv(ti->str,tc->str); + } + } + if (typeequiv) { + /* Already exists in the table. Just add additional types to the list */ + if (ti->clientdata) tc->clientdata = ti->clientdata; + head = tc; + next = tc->next; + goto l1; + } + tc = tc->prev; + } + head = ti; + next = 0; + + /* Place in list */ + ti->prev = *tl; + *tl = ti; + + /* Build linked lists */ + l1: + ret = head; + tc = ti + 1; + /* Patch up the rest of the links */ + while (tc->name) { + head->next = tc; + tc->prev = head; + head = tc; + tc++; + } + if (next) next->prev = head; + head->next = next; + + return ret; +} + +/* + Check the typename +*/ +SWIGRUNTIME swig_type_info * +SWIG_TypeCheck(const char *c, swig_type_info *ty) { + swig_type_info *s; + if (!ty) return 0; /* Void pointer */ + s = ty->next; /* First element always just a name */ + do { + if (strcmp(s->name,c) == 0) { + if (s == ty->next) return s; + /* Move s to the top of the linked list */ + s->prev->next = s->next; + if (s->next) { + s->next->prev = s->prev; + } + /* Insert s as second element in the list */ + s->next = ty->next; + if (ty->next) ty->next->prev = s; + ty->next = s; + s->prev = ty; + return s; + } + s = s->next; + } while (s && (s != ty->next)); + return 0; +} + +/* + Cast a pointer up an inheritance hierarchy +*/ +SWIGRUNTIMEINLINE void * +SWIG_TypeCast(swig_type_info *ty, void *ptr) { + return ((!ty) || (!ty->converter)) ? ptr : (*ty->converter)(ptr); +} + +/* + Dynamic pointer casting. Down an inheritance hierarchy +*/ +SWIGRUNTIME swig_type_info * +SWIG_TypeDynamicCast(swig_type_info *ty, void **ptr) { + swig_type_info *lastty = ty; + if (!ty || !ty->dcast) return ty; + while (ty && (ty->dcast)) { + ty = (*ty->dcast)(ptr); + if (ty) lastty = ty; + } + return lastty; +} + +/* + Return the name associated with this type +*/ +SWIGRUNTIMEINLINE const char * +SWIG_TypeName(const swig_type_info *ty) { + return ty->name; +} + +/* + Return the pretty name associated with this type, + that is an unmangled type name in a form presentable to the user. +*/ +SWIGRUNTIME const char * +SWIG_TypePrettyName(const swig_type_info *type) { + /* The "str" field contains the equivalent pretty names of the + type, separated by vertical-bar characters. We choose + to print the last name, as it is often (?) the most + specific. */ + if (type->str != NULL) { + const char *last_name = type->str; + const char *s; + for (s = type->str; *s; s++) + if (*s == '|') last_name = s+1; + return last_name; + } + else + return type->name; +} + +/* + Search for a swig_type_info structure +*/ +SWIGRUNTIME swig_type_info * +SWIG_TypeQueryTL(swig_type_info *tl, const char *name) { + swig_type_info *ty = tl; + while (ty) { + if (ty->str && (SWIG_TypeEquiv(ty->str,name))) return ty; + if (ty->name && (strcmp(name,ty->name) == 0)) return ty; + ty = ty->prev; + } + return 0; +} + +/* + Set the clientdata field for a type +*/ +SWIGRUNTIME void +SWIG_TypeClientDataTL(swig_type_info *tl, swig_type_info *ti, void *clientdata) { + swig_type_info *tc, *equiv; + if (ti->clientdata) return; + /* if (ti->clientdata == clientdata) return; */ + ti->clientdata = clientdata; + equiv = ti->next; + while (equiv) { + if (!equiv->converter) { + tc = tl; + while (tc) { + if ((strcmp(tc->name, equiv->name) == 0)) + SWIG_TypeClientDataTL(tl,tc,clientdata); + tc = tc->prev; + } + } + equiv = equiv->next; + } +} + +/* + Pack binary data into a string +*/ +SWIGRUNTIME char * +SWIG_PackData(char *c, void *ptr, size_t sz) { + static char hex[17] = "0123456789abcdef"; + unsigned char *u = (unsigned char *) ptr; + const unsigned char *eu = u + sz; + register unsigned char uu; + for (; u != eu; ++u) { + uu = *u; + *(c++) = hex[(uu & 0xf0) >> 4]; + *(c++) = hex[uu & 0xf]; + } + return c; +} + +/* + Unpack binary data from a string +*/ +SWIGRUNTIME const char * +SWIG_UnpackData(const char *c, void *ptr, size_t sz) { + register unsigned char *u = (unsigned char *) ptr; + register const unsigned char *eu = u + sz; + for (; u != eu; ++u) { + register int d = *(c++); + register unsigned char uu = 0; + if ((d >= '0') && (d <= '9')) + uu = ((d - '0') << 4); + else if ((d >= 'a') && (d <= 'f')) + uu = ((d - ('a'-10)) << 4); + else + return (char *) 0; + d = *(c++); + if ((d >= '0') && (d <= '9')) + uu |= (d - '0'); + else if ((d >= 'a') && (d <= 'f')) + uu |= (d - ('a'-10)); + else + return (char *) 0; + *u = uu; + } + return c; +} + +/* + This function will propagate the clientdata field of type to any new + swig_type_info structures that have been added into the list of + equivalent types. It is like calling SWIG_TypeClientData(type, + clientdata) a second time. +*/ +SWIGRUNTIME void +SWIG_PropagateClientDataTL(swig_type_info *tl, swig_type_info *type) { + swig_type_info *equiv = type->next; + swig_type_info *tc; + if (!type->clientdata) return; + while (equiv) { + if (!equiv->converter) { + tc = tl; + while (tc) { + if ((strcmp(tc->name, equiv->name) == 0) && !tc->clientdata) + SWIG_TypeClientDataTL(tl,tc, type->clientdata); + tc = tc->prev; + } + } + equiv = equiv->next; + } +} + +/* + Pack 'void *' into a string buffer. +*/ +SWIGRUNTIME char * +SWIG_PackVoidPtr(char *buff, void *ptr, const char *name, size_t bsz) { + char *r = buff; + if ((2*sizeof(void *) + 2) > bsz) return 0; + *(r++) = '_'; + r = SWIG_PackData(r,&ptr,sizeof(void *)); + if (strlen(name) + 1 > (bsz - (r - buff))) return 0; + strcpy(r,name); + return buff; +} + +SWIGRUNTIME const char * +SWIG_UnpackVoidPtr(const char *c, void **ptr, const char *name) { + if (*c != '_') { + if (strcmp(c,"NULL") == 0) { + *ptr = (void *) 0; + return name; + } else { + return 0; + } + } + return SWIG_UnpackData(++c,ptr,sizeof(void *)); +} + +SWIGRUNTIME char * +SWIG_PackDataName(char *buff, void *ptr, size_t sz, const char *name, size_t bsz) { + char *r = buff; + size_t lname = (name ? strlen(name) : 0); + if ((2*sz + 2 + lname) > bsz) return 0; + *(r++) = '_'; + r = SWIG_PackData(r,ptr,sz); + if (lname) { + strncpy(r,name,lname+1); + } else { + *r = 0; + } + return buff; +} + +SWIGRUNTIME const char * +SWIG_UnpackDataName(const char *c, void *ptr, size_t sz, const char *name) { + if (*c != '_') { + if (strcmp(c,"NULL") == 0) { + memset(ptr,0,sz); + return name; + } else { + return 0; + } + } + return SWIG_UnpackData(++c,ptr,sz); +} + +#ifdef __cplusplus +} +#endif + +/*********************************************************************** + * common.swg + * + * This file contains generic SWIG runtime support for pointer + * type checking as well as a few commonly used macros to control + * external linkage. + * + * Author : David Beazley (beazley@cs.uchicago.edu) + * + * Copyright (c) 1999-2000, The University of Chicago + * + * This file may be freely redistributed without license or fee provided + * this copyright message remains intact. + ************************************************************************/ + + +#if defined(_WIN32) || defined(__WIN32__) || defined(__CYGWIN__) +# if !defined(STATIC_LINKED) +# define SWIGEXPORT(a) __declspec(dllexport) a +# else +# define SWIGEXPORT(a) a +# endif +#else +# define SWIGEXPORT(a) a +#endif + +#ifdef __cplusplus +extern "C" { +#endif + + +/*************************************************************************/ + + +/* The static type info list */ + +static swig_type_info *swig_type_list = 0; +static swig_type_info **swig_type_list_handle = &swig_type_list; + + +/* Register a type mapping with the type-checking */ +static swig_type_info * +SWIG_TypeRegister(swig_type_info *ti) { + return SWIG_TypeRegisterTL(swig_type_list_handle, ti); +} + +/* Search for a swig_type_info structure */ +static swig_type_info * +SWIG_TypeQuery(const char *name) { + return SWIG_TypeQueryTL(*swig_type_list_handle, name); +} + +/* Set the clientdata field for a type */ +static void +SWIG_TypeClientData(swig_type_info *ti, void *clientdata) { + SWIG_TypeClientDataTL(*swig_type_list_handle, ti, clientdata); +} + +/* This function will propagate the clientdata field of type to +* any new swig_type_info structures that have been added into the list +* of equivalent types. It is like calling +* SWIG_TypeClientData(type, clientdata) a second time. +*/ +static void +SWIG_PropagateClientData(swig_type_info *type) { + SWIG_PropagateClientDataTL(*swig_type_list_handle, type); +} + +#ifdef __cplusplus +} +#endif + +/* ---------------------------------------------------------------------- -*- c -*- + * perl5.swg + * + * Perl5 runtime library + * $Header: /cvsroot/swig/SWIG/Lib/perl5/perlrun.swg,v 1.20 2004/11/29 23:13:57 wuzzeb Exp $ + * ----------------------------------------------------------------------------- */ + +#define SWIGPERL +#define SWIGPERL5 +#ifdef __cplusplus +/* Needed on some windows machines---since MS plays funny games with the header files under C++ */ +#include +#include +extern "C" { +#endif +#include "EXTERN.h" +#include "perl.h" +#include "XSUB.h" + +/* Get rid of free and malloc defined by perl */ +#undef free +#undef malloc + +#ifndef pTHX_ +#define pTHX_ +#endif + +#include +#ifdef __cplusplus +} +#endif + +/* Macro to call an XS function */ + +#ifdef PERL_OBJECT +# define SWIG_CALLXS(_name) _name(cv,pPerl) +#else +# ifndef MULTIPLICITY +# define SWIG_CALLXS(_name) _name(cv) +# else +# define SWIG_CALLXS(_name) _name(PERL_GET_THX, cv) +# endif +#endif + +/* Contract support */ + +#define SWIG_contract_assert(expr,msg) if (!(expr)) { SWIG_croak(msg); } else + +/* Note: SwigMagicFuncHack is a typedef used to get the C++ compiler to just shut up already */ + +#ifdef PERL_OBJECT +#define MAGIC_PPERL CPerlObj *pPerl = (CPerlObj *) this; +typedef int (CPerlObj::*SwigMagicFunc)(SV *, MAGIC *); + +#ifdef __cplusplus +extern "C" { +#endif +typedef int (CPerlObj::*SwigMagicFuncHack)(SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + +#define SWIG_MAGIC(a,b) (SV *a, MAGIC *b) +#define SWIGCLASS_STATIC +#else +#define MAGIC_PPERL +#define SWIGCLASS_STATIC static +#ifndef MULTIPLICITY +#define SWIG_MAGIC(a,b) (SV *a, MAGIC *b) +typedef int (*SwigMagicFunc)(SV *, MAGIC *); + +#ifdef __cplusplus +extern "C" { +#endif +typedef int (*SwigMagicFuncHack)(SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + + +#else +#define SWIG_MAGIC(a,b) (struct interpreter *interp, SV *a, MAGIC *b) +typedef int (*SwigMagicFunc)(struct interpreter *, SV *, MAGIC *); +#ifdef __cplusplus +extern "C" { +#endif +typedef int (*SwigMagicFuncHack)(struct interpreter *, SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + +#endif +#endif + +#if defined(WIN32) && defined(PERL_OBJECT) && !defined(PerlIO_exportFILE) +#define PerlIO_exportFILE(fh,fl) (FILE*)(fh) +#endif + +/* Modifications for newer Perl 5.005 releases */ + +#if !defined(PERL_REVISION) || ((PERL_REVISION >= 5) && ((PERL_VERSION < 5) || ((PERL_VERSION == 5) && (PERL_SUBVERSION < 50)))) +# ifndef PL_sv_yes +# define PL_sv_yes sv_yes +# endif +# ifndef PL_sv_undef +# define PL_sv_undef sv_undef +# endif +# ifndef PL_na +# define PL_na na +# endif +#endif + +#include + +#ifdef __cplusplus +extern "C" { +#endif + +#define SWIG_OWNER 1 +#define SWIG_SHADOW 2 + +/* Common SWIG API */ + +#ifdef PERL_OBJECT +# define SWIG_ConvertPtr(obj, pp, type, flags) \ + SWIG_Perl_ConvertPtr(pPerl, obj, pp, type, flags) +# define SWIG_NewPointerObj(p, type, flags) \ + SWIG_Perl_NewPointerObj(pPerl, p, type, flags) +# define SWIG_MakePackedObj(sv, p, s, type) \ + SWIG_Perl_MakePackedObj(pPerl, sv, p, s, type) +# define SWIG_ConvertPacked(obj, p, s, type, flags) \ + SWIG_Perl_ConvertPacked(pPerl, obj, p, s, type, flags) + +#else +# define SWIG_ConvertPtr(obj, pp, type, flags) \ + SWIG_Perl_ConvertPtr(obj, pp, type, flags) +# define SWIG_NewPointerObj(p, type, flags) \ + SWIG_Perl_NewPointerObj(p, type, flags) +# define SWIG_MakePackedObj(sv, p, s, type) \ + SWIG_Perl_MakePackedObj(sv, p, s, type ) +# define SWIG_ConvertPacked(obj, p, s, type, flags) \ + SWIG_Perl_ConvertPacked(obj, p, s, type, flags) +#endif + +/* Perl-specific API */ +#ifdef PERL_OBJECT +# define SWIG_MakePtr(sv, ptr, type, flags) \ + SWIG_Perl_MakePtr(pPerl, sv, ptr, type, flags) +# define SWIG_SetError(str) \ + SWIG_Perl_SetError(pPerl, str) +#else +# define SWIG_MakePtr(sv, ptr, type, flags) \ + SWIG_Perl_MakePtr(sv, ptr, type, flags) +# define SWIG_SetError(str) \ + SWIG_Perl_SetError(str) +# define SWIG_SetErrorSV(str) \ + SWIG_Perl_SetErrorSV(str) +#endif + +#define SWIG_SetErrorf SWIG_Perl_SetErrorf + + +#ifdef PERL_OBJECT +# define SWIG_MAYBE_PERL_OBJECT CPerlObj *pPerl, +#else +# define SWIG_MAYBE_PERL_OBJECT +#endif + +static swig_type_info ** +SWIG_Perl_GetTypeListHandle() { + static void *type_pointer = (void *)0; + SV *pointer; + + /* first check if pointer already created */ + if (!type_pointer) { + pointer = get_sv("swig_runtime_data::type_pointer" SWIG_RUNTIME_VERSION SWIG_TYPE_TABLE_NAME, FALSE); + if (pointer && SvOK(pointer)) { + type_pointer = INT2PTR(swig_type_info **, SvIV(pointer)); + } + } + + return (swig_type_info **) type_pointer; +} + +/* + Search for a swig_type_info structure + */ +SWIGRUNTIMEINLINE swig_type_info * +SWIG_Perl_GetTypeList() { + swig_type_info **tlh = SWIG_Perl_GetTypeListHandle(); + return tlh ? *tlh : (swig_type_info*)0; +} + +#define SWIG_Runtime_GetTypeList SWIG_Perl_GetTypeList + +static swig_type_info * +SWIG_Perl_TypeCheckRV(SWIG_MAYBE_PERL_OBJECT SV *rv, swig_type_info *ty) { + swig_type_info *s; + if (!ty) return 0; /* Void pointer */ + s = ty->next; /* First element always just a name */ + do { + if (sv_derived_from(rv, (char *) s->name)) { + if (s == ty->next) return s; + /* Move s to the top of the linked list */ + s->prev->next = s->next; + if (s->next) { + s->next->prev = s->prev; + } + /* Insert s as second element in the list */ + s->next = ty->next; + if (ty->next) ty->next->prev = s; + ty->next = s; + s->prev = ty; + return s; + } + s = s->next; + } while (s && (s != ty->next)); + return 0; +} + +/* Function for getting a pointer value */ + +static int +SWIG_Perl_ConvertPtr(SWIG_MAYBE_PERL_OBJECT SV *sv, void **ptr, swig_type_info *_t, int flags) { + swig_type_info *tc; + void *voidptr = (void *)0; + + /* If magical, apply more magic */ + if (SvGMAGICAL(sv)) + mg_get(sv); + + /* Check to see if this is an object */ + if (sv_isobject(sv)) { + SV *tsv = (SV*) SvRV(sv); + IV tmp = 0; + if ((SvTYPE(tsv) == SVt_PVHV)) { + MAGIC *mg; + if (SvMAGICAL(tsv)) { + mg = mg_find(tsv,'P'); + if (mg) { + sv = mg->mg_obj; + if (sv_isobject(sv)) { + tmp = SvIV((SV*)SvRV(sv)); + } + } + } else { + return -1; + } + } else { + tmp = SvIV((SV*)SvRV(sv)); + } + voidptr = (void *)tmp; + if (!_t) { + *(ptr) = voidptr; + return 0; + } + } else if (! SvOK(sv)) { /* Check for undef */ + *(ptr) = (void *) 0; + return 0; + } else if (SvTYPE(sv) == SVt_RV) { /* Check for NULL pointer */ + *(ptr) = (void *) 0; + if (!SvROK(sv)) + return 0; + else + return -1; + } else { /* Don't know what it is */ + *(ptr) = (void *) 0; + return -1; + } + if (_t) { + /* Now see if the types match */ + char *_c = HvNAME(SvSTASH(SvRV(sv))); + tc = SWIG_TypeCheck(_c,_t); + if (!tc) { + *ptr = voidptr; + return -1; + } + *ptr = SWIG_TypeCast(tc,voidptr); + return 0; + } + *ptr = voidptr; + return 0; +} + +static void +SWIG_Perl_MakePtr(SWIG_MAYBE_PERL_OBJECT SV *sv, void *ptr, swig_type_info *t, int flags) { + if (ptr && (flags & SWIG_SHADOW)) { + SV *self; + SV *obj=newSV(0); + HV *hash=newHV(); + HV *stash; + sv_setref_pv(obj, (char *) t->name, ptr); + stash=SvSTASH(SvRV(obj)); + if (flags & SWIG_OWNER) { + HV *hv; + GV *gv=*(GV**)hv_fetch(stash, "OWNER", 5, TRUE); + if (!isGV(gv)) + gv_init(gv, stash, "OWNER", 5, FALSE); + hv=GvHVn(gv); + hv_store_ent(hv, obj, newSViv(1), 0); + } + sv_magic((SV *)hash, (SV *)obj, 'P', Nullch, 0); + SvREFCNT_dec(obj); + self=newRV_noinc((SV *)hash); + sv_setsv(sv, self); + SvREFCNT_dec((SV *)self); + sv_bless(sv, stash); + } + else { + sv_setref_pv(sv, (char *) t->name, ptr); + } +} + +static SWIGINLINE SV * +SWIG_Perl_NewPointerObj(SWIG_MAYBE_PERL_OBJECT void *ptr, swig_type_info *t, int flags) { + SV *result = sv_newmortal(); + SWIG_MakePtr(result, ptr, t, flags); + return result; +} + +static void + SWIG_Perl_MakePackedObj(SWIG_MAYBE_PERL_OBJECT SV *sv, void *ptr, int sz, swig_type_info *type) { + char result[1024]; + char *r = result; + if ((2*sz + 1 + strlen(type->name)) > 1000) return; + *(r++) = '_'; + r = SWIG_PackData(r,ptr,sz); + strcpy(r,type->name); + sv_setpv(sv, result); +} + +/* Convert a packed value value */ +static int +SWIG_Perl_ConvertPacked(SWIG_MAYBE_PERL_OBJECT SV *obj, void *ptr, int sz, swig_type_info *ty, int flags) { + swig_type_info *tc; + const char *c = 0; + + if ((!obj) || (!SvOK(obj))) return -1; + c = SvPV(obj, PL_na); + /* Pointer values must start with leading underscore */ + if (*c != '_') return -1; + c++; + c = SWIG_UnpackData(c,ptr,sz); + if (ty) { + tc = SWIG_TypeCheck(c,ty); + if (!tc) return -1; + } + return 0; +} + +static SWIGINLINE void +SWIG_Perl_SetError(SWIG_MAYBE_PERL_OBJECT const char *error) { + if (error) sv_setpv(perl_get_sv("@", TRUE), error); +} + +static SWIGINLINE void +SWIG_Perl_SetErrorSV(SWIG_MAYBE_PERL_OBJECT SV *error) { + if (error) sv_setsv(perl_get_sv("@", TRUE), error); +} + +static void +SWIG_Perl_SetErrorf(const char *fmt, ...) { + va_list args; + va_start(args, fmt); + sv_vsetpvfn(perl_get_sv("@", TRUE), fmt, strlen(fmt), &args, Null(SV**), 0, Null(bool*)); + va_end(args); +} + +/* Macros for low-level exception handling */ +#define SWIG_fail goto fail +#define SWIG_croak(x) { SWIG_SetError(x); goto fail; } +#define SWIG_croakSV(x) { SWIG_SetErrorSV(x); goto fail; } +/* most preprocessors do not support vararg macros :-( */ +/* #define SWIG_croakf(x...) { SWIG_SetErrorf(x); goto fail; } */ + + +typedef XS(SwigPerlWrapper); +typedef SwigPerlWrapper *SwigPerlWrapperPtr; + +/* Structure for command table */ +typedef struct { + const char *name; + SwigPerlWrapperPtr wrapper; +} swig_command_info; + +/* Information for constant table */ + +#define SWIG_INT 1 +#define SWIG_FLOAT 2 +#define SWIG_STRING 3 +#define SWIG_POINTER 4 +#define SWIG_BINARY 5 + +/* Constant information structure */ +typedef struct swig_constant_info { + int type; + const char *name; + long lvalue; + double dvalue; + void *pvalue; + swig_type_info **ptype; +} swig_constant_info; + +#ifdef __cplusplus +} +#endif + +/* Structure for variable table */ +typedef struct { + const char *name; + SwigMagicFunc set; + SwigMagicFunc get; + swig_type_info **type; +} swig_variable_info; + +/* Magic variable code */ +#ifndef PERL_OBJECT +#define swig_create_magic(s,a,b,c) _swig_create_magic(s,a,b,c) + #ifndef MULTIPLICITY + static void _swig_create_magic(SV *sv, char *name, int (*set)(SV *, MAGIC *), int (*get)(SV *,MAGIC *)) { + #else + static void _swig_create_magic(SV *sv, char *name, int (*set)(struct interpreter*, SV *, MAGIC *), int (*get)(struct interpreter*, SV *,MAGIC *)) { + #endif +#else +# define swig_create_magic(s,a,b,c) _swig_create_magic(pPerl,s,a,b,c) +static void _swig_create_magic(CPerlObj *pPerl, SV *sv, const char *name, int (CPerlObj::*set)(SV *, MAGIC *), int (CPerlObj::*get)(SV *, MAGIC *)) { +#endif + MAGIC *mg; + sv_magic(sv,sv,'U',(char *) name,strlen(name)); + mg = mg_find(sv,'U'); + mg->mg_virtual = (MGVTBL *) malloc(sizeof(MGVTBL)); + mg->mg_virtual->svt_get = (SwigMagicFuncHack) get; + mg->mg_virtual->svt_set = (SwigMagicFuncHack) set; + mg->mg_virtual->svt_len = 0; + mg->mg_virtual->svt_clear = 0; + mg->mg_virtual->svt_free = 0; +} + + + + + + +#ifdef do_open + #undef do_open +#endif +#ifdef do_close + #undef do_close +#endif +#ifdef scalar + #undef scalar +#endif +#ifdef list + #undef list +#endif +#ifdef apply + #undef apply +#endif +#ifdef convert + #undef convert +#endif +#ifdef Error + #undef Error +#endif +#ifdef form + #undef form +#endif +#ifdef vform + #undef vform +#endif +#ifdef LABEL + #undef LABEL +#endif +#ifdef METHOD + #undef METHOD +#endif +#ifdef Move + #undef Move +#endif +#ifdef yylex + #undef yylex +#endif +#ifdef yyparse + #undef yyparse +#endif +#ifdef yyerror + #undef yyerror +#endif +#ifdef invert + #undef invert +#endif +#ifdef ref + #undef ref +#endif +#ifdef ENTER + #undef ENTER +#endif + + +/* -------- TYPES TABLE (BEGIN) -------- */ + +#define SWIGTYPE_p_SOLUTION swig_types[0] +#define SWIGTYPE_p_intArray swig_types[1] +#define SWIGTYPE_p_double swig_types[2] +#define SWIGTYPE_p_bond swig_types[3] +#define SWIGTYPE_p_plist swig_types[4] +#define SWIGTYPE_p_cpair swig_types[5] +#define SWIGTYPE_p_swString swig_types[6] +#define SWIGTYPE_p_float swig_types[7] +#define SWIGTYPE_p_void swig_types[8] +#define SWIGTYPE_p_floatArray swig_types[9] +#define SWIGTYPE_p_doubleArray swig_types[10] +#define SWIGTYPE_p_p_void swig_types[11] +#define SWIGTYPE_p_short swig_types[12] +#define SWIGTYPE_p_p_char swig_types[13] +#define SWIGTYPE_p_char swig_types[14] +#define SWIGTYPE_p_unsigned_short swig_types[15] +#define SWIGTYPE_p_paramT swig_types[16] +#define SWIGTYPE_p_Tree swig_types[17] +#define SWIGTYPE_p_FILE swig_types[18] +#define SWIGTYPE_p_int swig_types[19] +static swig_type_info *swig_types[21]; + +/* -------- TYPES TABLE (END) -------- */ + +#define SWIG_init boot_RNA + +#define SWIG_name "RNAc::boot_RNA" +#define SWIG_prefix "RNAc::" + +#ifdef __cplusplus +extern "C" +#endif +#ifndef PERL_OBJECT +#ifndef MULTIPLICITY +SWIGEXPORT(void) SWIG_init (CV* cv); +#else +SWIGEXPORT(void) SWIG_init (pTHXo_ CV* cv); +#endif +#else +SWIGEXPORT(void) SWIG_init (CV *cv, CPerlObj *); +#endif + + +#include "../H/utils.h" +#include "../H/fold_vars.h" +#undef fold +#include "../H/fold.h" +#include "../H/cofold.h" +#include "../H/part_func.h" +#include "../H/PS_dot.h" +#include "../H/inverse.h" +#include "../H/RNAstruct.h" +#include "../H/treedist.h" +#include "../H/stringdist.h" +#include "../H/profiledist.h" +#include "../H/dist_vars.h" +#include "../H/pair_mat.h" +#include "../H/subopt.h" +#include "../H/energy_const.h" +#include "../H/params.h" + + +static int *new_intP(int nelements) { + return (int *) calloc(nelements,sizeof(int)); +} + +static void delete_intP(int *ary) { + free(ary); +} + +static int intP_getitem(int *ary, int index) { + return ary[index]; +} +static void intP_setitem(int *ary, int index, int value) { + ary[index] = value; +} + + +typedef int intArray; + +static intArray *new_intArray(int nelements){ + return (int *) calloc(nelements,sizeof(int)); +} +static void delete_intArray(intArray *self){ + free(self); +} +static int intArray_getitem(intArray *self,int index){ + return self[index]; +} +static void intArray_setitem(intArray *self,int index,int value){ + self[index] = value; +} +static int *intArray_cast(intArray *self){ + return self; +} +static intArray *intArray_frompointer(int *t){ + return (intArray *) t; +} + +static float *new_floatP(int nelements) { + return (float *) calloc(nelements,sizeof(float)); +} + +static void delete_floatP(float *ary) { + free(ary); +} + +static float floatP_getitem(float *ary, int index) { + return ary[index]; +} +static void floatP_setitem(float *ary, int index, float value) { + ary[index] = value; +} + + +typedef float floatArray; + +static floatArray *new_floatArray(int nelements){ + return (float *) calloc(nelements,sizeof(float)); +} +static void delete_floatArray(floatArray *self){ + free(self); +} +static float floatArray_getitem(floatArray *self,int index){ + return self[index]; +} +static void floatArray_setitem(floatArray *self,int index,float value){ + self[index] = value; +} +static float *floatArray_cast(floatArray *self){ + return self; +} +static floatArray *floatArray_frompointer(float *t){ + return (floatArray *) t; +} + +static double *new_doubleP(int nelements) { + return (double *) calloc(nelements,sizeof(double)); +} + +static void delete_doubleP(double *ary) { + free(ary); +} + +static double doubleP_getitem(double *ary, int index) { + return ary[index]; +} +static void doubleP_setitem(double *ary, int index, double value) { + ary[index] = value; +} + + +typedef double doubleArray; + +static doubleArray *new_doubleArray(int nelements){ + return (double *) calloc(nelements,sizeof(double)); +} +static void delete_doubleArray(doubleArray *self){ + free(self); +} +static double doubleArray_getitem(doubleArray *self,int index){ + return self[index]; +} +static void doubleArray_setitem(doubleArray *self,int index,double value){ + self[index] = value; +} +static double *doubleArray_cast(doubleArray *self){ + return self; +} +static doubleArray *doubleArray_frompointer(double *t){ + return (doubleArray *) t; +} + +static short *new_shortP(int nelements) { + return (short *) calloc(nelements,sizeof(short)); +} + +static void delete_shortP(short *ary) { + free(ary); +} + +static short shortP_getitem(short *ary, int index) { + return ary[index]; +} +static void shortP_setitem(short *ary, int index, short value) { + ary[index] = value; +} + + +typedef struct SWIGCDATA { + char *data; + int len; +} SWIGCDATA; + + + +static SWIGCDATA cdata_void(void *ptr, int nelements) { + + + + SWIGCDATA d; + d.data = (char *) ptr; + + + + d.len = nelements; + + return d; +} + + + char *my_fold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = fold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } + +float energy_of_struct(char const *,char const *); +void free_arrays(void); +void initialize_fold(int); +void update_fold_params(void); + + char *my_cofold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = cofold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } + +void free_co_arrays(void); +void initialize_cofold(int); +void update_cofold_params(void); + + char *my_pf_fold(char *string, char *constraints, float *energy) { + char *struc; + float en; + struc = calloc(strlen(string)+1,sizeof(char)); + if (constraints && fold_constrained) + strncpy(struc, constraints, strlen(string)); + *energy = pf_fold(string, struc); + if (constraints) + strncpy(constraints, struc, strlen(constraints)); + return(struc); + } + +void init_pf_fold(int); +void free_pf_arrays(void); +void update_pf_params(int); +char bppm_symbol(float const *); +double mean_bp_dist(int); +char *pbacktrack(char *); + + char *my_inverse_fold(char *start, const char *target, float *cost) { + char *seq; + int n; + n = strlen(target); + seq = random_string(n, symbolset); + if (start) + strncpy(seq, start, strlen(start)); + *cost = inverse_fold(seq, target); + if (start) + /* for backward compatibility modify start */ + strncpy(start, seq, strlen(start)); + return(seq); + } + + + char *my_inverse_pf_fold(char *start, const char *target, float *cost) { + char *seq; + int n; + n = strlen(target); + seq = random_string(n, symbolset); + if (start) strncpy(seq, start, n); + *cost = inverse_pf_fold(seq, target); + if (start) + /* for backward compatibility modify start */ + strncpy(start, seq, strlen(start)); + return(seq); + } + +extern char *symbolset; +extern float final_cost; +extern int give_up; +extern int noGU; +extern int no_closingGU; +extern int tetra_loop; +extern int energy_set; +extern int dangles; +extern char *nonstandards; +extern double temperature; +extern int james_rule; +extern int logML; +extern int cut_point; +static bondT *bondT_get(bondT *self,int i){ + return self+i; + } +extern bondT *base_pair; +extern double *pr; +extern int *iindx; +extern double pf_scale; +extern int fold_constrained; +extern int do_backtrack; +extern int noLonelyPairs; +extern char backtrack_type; +static SOLUTION *SOLUTION_get(SOLUTION *self,int i){ +// static int size=-1; +// if (size<0) { +// SOLUTION *s; +// for (s=self; s->structure; s++); +// size= (int) (s-self); +// } +// if (i>=size) { +// warn("value out of range"); +// return NULL; +// } + return self+i; + } +static int SOLUTION_size(SOLUTION *self){ + SOLUTION *s; + for (s=self; s->structure; s++); + return (int)(s-self); + } +static void delete_SOLUTION(SOLUTION *self){ + SOLUTION *s; + for (s=self; s->structure; s++) free(s->structure); + free(self); + } +SOLUTION *subopt(char *,char *,int,FILE *); +extern int subopt_sorted; + +double get_pr(int i, int j) { + int ii; + if (i>j) {ii=i; i=j; j=ii;} + return pr[iindx[i]-j]; +} + +Tree *make_tree(char *); +float tree_edit_distance(Tree *,Tree *); +void print_tree(Tree *); +void free_tree(Tree *); +swString *Make_swString(char *); +float string_edit_distance(swString *,swString *); +float *Make_bp_profile(int); +float profile_edit_distance(float const *,float const *); +void print_bppm(float const *); +void free_profile(float *); +void *space(unsigned int); +void *xrealloc(void *,unsigned int); +void nrerror(char const []); +void init_rand(void); +extern unsigned short xsubi[3]; +double urn(void); +int int_urn(int,int); +void filecopy(FILE *,FILE *); +char *time_stamp(void); +char *random_string(int,char const []); +int hamming(char const *,char const *); +char *get_line(FILE const *); +char *pack_structure(char const *); +char *unpack_structure(char const *); +short *make_pair_table(char const *); +int bp_distance(char const *,char const *); +void read_parameter_file(char *); +void write_parameter_file(char *); + +void *deref_any(void **ptr, int index) { + /* dereference arbitray pointer */ + return (void *) ptr[index]; +} + +paramT *scale_parameters(void); +paramT *copy_parameters(void); +paramT *set_parameters(paramT *); + +char *get_aligned_line(int i) { + i = i % 2; + return aligned_line[i]; +} + + + short *make_loop_index(const char *structure) { + /* number each position by which loop it belongs to (positions start at 0) */ + int i,j,hx,l,nl; + int length; + short *stack; + short *loop; + length = strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + loop = (short *) space(sizeof(short)*(length+2)); + hx=l=nl=0; + for (i=0; i0) + l = loop[stack[hx-1]]; /* index of enclosing loop */ + else l=0; /* external loop has index 0 */ + if (hx<0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in make_pair_table"); + } + } + } + free(stack); + return loop; + } + + +float energy_of_move(const char *string, char *structure, int mi, int mj) { + extern int energy_of_struct_pt(const char *string, short * ptable, + short *s, short *s1); +#define ILLEGAL 999.; + int i,j,hx,l,nl; + int length; + short *stack, *table, *loop; + short *S, *S1; + int energy; + + if (mj<0) { + if ((structure[-mi]!='(') || (structure[-mj]!=')')) + return 1001; /* illegal delete pair */ + } else + if ((structure[mi]!='.') || (structure[mj]!='.')) + return 1002; /* illegal add pair */ + + /* make the pair table and loop index l*/ + length = strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + loop = (short *) space(sizeof(short)*(length+2)); + table = (short *) space(sizeof(short)*(length+2)); + table[0] = length; + hx=l=nl=0; + for (i=1; i<=length; i++) { + if (structure[i-1] == '(') { + nl++; l=nl; + stack[hx++]=i; + } + loop[i]=l; + if (structure[i-1] ==')') { + j=stack[--hx]; + if (hx>0) + l = loop[stack[hx-1]]; /* index of enclosing loop */ + else l=0; /* external loop has index 0 */ + if (hx<0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in energy_of_move"); + } + table[i]=j; + table[j]=i; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in energy_of_move"); + } + + if (loop[abs(mi)+1] != loop[abs(mj)+1]) { /* not in same loop => illegal */ + free(stack); + free(loop); + free(table); + return 1003.; + } + + /* if we get here the move is legal */ + if (mj<0) { /* delete pair */ + structure[-mi] = '.'; + structure[-mj] = '.'; + table[-mi+1] = table[-mj+1] = 0; + } else { /* insert pair */ + structure[mi] = '('; + structure[mj] = ')'; + table[mi+1] = mj+1; + table[mj+1] = mi+1; + } + + S = (short *) space(sizeof(short)*(length+1)); + S[0] = length; + for (i=1; i<=length; i++) { + char *pos; + pos = strchr(Law_and_Order, string[i-1]); + if (pos==NULL) S[i]=0; + else S[i] = pos-Law_and_Order; + } + + energy = energy_of_struct_pt(string, table, S, S); + + free(S); + free(stack); + free(loop); + free(table); + return (float) energy/100.; +} + +int PS_rna_plot(char *,char *,char *); +int PS_rna_plot_a(char *,char *,char *,char *,char *); +int gmlRNA(char *,char *,char *,char); +int ssv_rna_plot(char *,char *,char *); +int svg_rna_plot(char *,char *,char *); +int xrna_plot(char *,char *,char *); +int PS_dot_plot(char *,char *); +extern int rna_plot_type; +int PS_color_dot_plot(char *,cpair *,char *); +int PS_dot_plot_list(char *,char *,struct plist *,struct plist *,char *); +#ifdef PERL_OBJECT +#define MAGIC_CLASS _wrap_RNA_var:: +class _wrap_RNA_var : public CPerlObj { +public: +#else +#define MAGIC_CLASS +#endif +SWIGCLASS_STATIC int swig_magic_readonly(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + sv = sv; mg = mg; + croak("Value is read-only."); + return 0; +} +SWIGCLASS_STATIC int _wrap_set_symbolset(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + char *_a = (char *) SvPV(sv,PL_na); + if (symbolset) free((char *) symbolset); + symbolset = (char *) malloc(strlen(_a)+1); + strcpy((char *)symbolset,_a); + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_symbolset(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + if (symbolset) { + sv_setpv((SV*)sv, (char *) symbolset); + } else { + sv_setsv((SV*)sv, &PL_sv_undef); + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_final_cost(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + final_cost = (float) SvNV(sv); + + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_final_cost(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setnv(sv, (double) final_cost); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_give_up(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + give_up = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_give_up(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) give_up); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_noGU(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + noGU = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_noGU(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) noGU); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_no_closingGU(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + no_closingGU = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_no_closingGU(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) no_closingGU); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_tetra_loop(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + tetra_loop = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_tetra_loop(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) tetra_loop); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_energy_set(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + energy_set = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_energy_set(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) energy_set); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_dangles(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + dangles = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_dangles(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) dangles); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_nonstandards(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + char *_a = (char *) SvPV(sv,PL_na); + if (nonstandards) free((char *) nonstandards); + nonstandards = (char *) malloc(strlen(_a)+1); + strcpy((char *)nonstandards,_a); + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_nonstandards(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + if (nonstandards) { + sv_setpv((SV*)sv, (char *) nonstandards); + } else { + sv_setsv((SV*)sv, &PL_sv_undef); + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_temperature(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + temperature = (double) SvNV(sv); + + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_temperature(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setnv(sv, (double) temperature); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_james_rule(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + james_rule = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_james_rule(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) james_rule); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_logML(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + logML = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_logML(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) logML); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_cut_point(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + cut_point = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_cut_point(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) cut_point); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_base_pair(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + void *temp; + if (SWIG_ConvertPtr(sv, (void **) &base_pair, SWIGTYPE_p_bond,0) < 0) { + croak("Type error in argument $argnum of base_pair. Expected _p_bond"); + } + base_pair = (bondT *) temp; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_base_pair(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) base_pair); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_pr(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + void *temp; + if (SWIG_ConvertPtr(sv, (void **) &pr, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument $argnum of pr. Expected _p_double"); + } + pr = (double *) temp; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_pr(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) pr); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_iindx(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + void *temp; + if (SWIG_ConvertPtr(sv, (void **) &iindx, SWIGTYPE_p_int,0) < 0) { + croak("Type error in argument $argnum of iindx. Expected _p_int"); + } + iindx = (int *) temp; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_iindx(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) iindx); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_pf_scale(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + pf_scale = (double) SvNV(sv); + + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_pf_scale(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setnv(sv, (double) pf_scale); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_fold_constrained(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + fold_constrained = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_fold_constrained(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) fold_constrained); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_do_backtrack(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + do_backtrack = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_do_backtrack(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) do_backtrack); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_noLonelyPairs(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + noLonelyPairs = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_noLonelyPairs(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) noLonelyPairs); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_backtrack_type(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + backtrack_type = (char) *SvPV(sv,PL_na); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_backtrack_type(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setpvn((SV *) sv, &backtrack_type, 1); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_subopt_sorted(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + subopt_sorted = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_subopt_sorted(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) subopt_sorted); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_loop_size(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + int i; + int *temp; + int *b = (int *) loop_size; + if (SWIG_ConvertPtr(sv, (void **) &temp, SWIGTYPE_p_int,0) < 0) { + croak("Type error in argument $argnum of loop_size. Expected _p_int"); + } + for (i = 0; i < 1000; i++) b[i] = temp[i]; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_loop_size(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) loop_size); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_helix_size(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + int i; + int *temp; + int *b = (int *) helix_size; + if (SWIG_ConvertPtr(sv, (void **) &temp, SWIGTYPE_p_int,0) < 0) { + croak("Type error in argument $argnum of helix_size. Expected _p_int"); + } + for (i = 0; i < 1000; i++) b[i] = temp[i]; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_helix_size(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) helix_size); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_loop_degree(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + int i; + int *temp; + int *b = (int *) loop_degree; + if (SWIG_ConvertPtr(sv, (void **) &temp, SWIGTYPE_p_int,0) < 0) { + croak("Type error in argument $argnum of loop_degree. Expected _p_int"); + } + for (i = 0; i < 1000; i++) b[i] = temp[i]; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_loop_degree(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) loop_degree); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_loops(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + loops = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_loops(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) loops); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_unpaired(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + unpaired = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_unpaired(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) unpaired); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_pairs(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + pairs = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_pairs(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) pairs); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_edit_backtrack(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + edit_backtrack = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_edit_backtrack(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) edit_backtrack); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_aligned_line(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + int i; + char * *temp; + char * *b = (char * *) aligned_line; + if (SWIG_ConvertPtr(sv, (void **) &temp, SWIGTYPE_p_p_char,0) < 0) { + croak("Type error in argument $argnum of aligned_line. Expected _p_p_char"); + } + for (i = 0; i < 2; i++) b[i] = temp[i]; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_aligned_line(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) aligned_line); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_cost_matrix(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + cost_matrix = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_cost_matrix(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) cost_matrix); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_xsubi(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + { + int i; + unsigned short *temp; + unsigned short *b = (unsigned short *) xsubi; + if (SWIG_ConvertPtr(sv, (void **) &temp, SWIGTYPE_p_unsigned_short,0) < 0) { + croak("Type error in argument $argnum of xsubi. Expected _p_unsigned_short"); + } + for (i = 0; i < 3; i++) b[i] = temp[i]; + } + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_xsubi(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(SvRV(sv),(IV) xsubi); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_set_rna_plot_type(pTHX_ SV* sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + rna_plot_type = (int) SvIV(sv); + return 1; +} + + +SWIGCLASS_STATIC int _wrap_val_rna_plot_type(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + mg = mg; + sv_setiv(sv, (IV) rna_plot_type); + return 1; +} + + + + +#ifdef PERL_OBJECT +}; +#endif + +#ifdef __cplusplus +extern "C" { +#endif +XS(_wrap_new_intP) { + { + int arg1 ; + int *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_intP(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (int *)new_intP(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_int, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_intP) { + { + int *arg1 = (int *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_intP(ary);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_int,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_intP. Expected _p_int"); + } + } + delete_intP(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intP_getitem) { + { + int *arg1 = (int *) 0 ; + int arg2 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: intP_getitem(ary,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_int,0) < 0) { + SWIG_croak("Type error in argument 1 of intP_getitem. Expected _p_int"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (int)intP_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intP_setitem) { + { + int *arg1 = (int *) 0 ; + int arg2 ; + int arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: intP_setitem(ary,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_int,0) < 0) { + SWIG_croak("Type error in argument 1 of intP_setitem. Expected _p_int"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (int) SvIV(ST(2)); + intP_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_intArray) { + { + int arg1 ; + intArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_intArray(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (intArray *)new_intArray(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_intArray, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_intArray) { + { + intArray *arg1 = (intArray *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_intArray(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_intArray,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_intArray. Expected _p_intArray"); + } + } + delete_intArray(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intArray_getitem) { + { + intArray *arg1 = (intArray *) 0 ; + int arg2 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: intArray_getitem(self,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_intArray,0) < 0) { + SWIG_croak("Type error in argument 1 of intArray_getitem. Expected _p_intArray"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (int)intArray_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intArray_setitem) { + { + intArray *arg1 = (intArray *) 0 ; + int arg2 ; + int arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: intArray_setitem(self,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_intArray,0) < 0) { + SWIG_croak("Type error in argument 1 of intArray_setitem. Expected _p_intArray"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (int) SvIV(ST(2)); + intArray_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intArray_cast) { + { + intArray *arg1 = (intArray *) 0 ; + int *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: intArray_cast(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_intArray,0) < 0) { + SWIG_croak("Type error in argument 1 of intArray_cast. Expected _p_intArray"); + } + } + result = (int *)intArray_cast(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_int, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_intArray_frompointer) { + { + int *arg1 = (int *) 0 ; + intArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: intArray_frompointer(t);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_int,0) < 0) { + SWIG_croak("Type error in argument 1 of intArray_frompointer. Expected _p_int"); + } + } + result = (intArray *)intArray_frompointer(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_intArray, SWIG_SHADOW|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_floatP) { + { + int arg1 ; + float *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_floatP(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (float *)new_floatP(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_float, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_floatP) { + { + float *arg1 = (float *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_floatP(ary);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_floatP. Expected _p_float"); + } + } + delete_floatP(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatP_getitem) { + { + float *arg1 = (float *) 0 ; + int arg2 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: floatP_getitem(ary,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of floatP_getitem. Expected _p_float"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (float)floatP_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatP_setitem) { + { + float *arg1 = (float *) 0 ; + int arg2 ; + float arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: floatP_setitem(ary,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of floatP_setitem. Expected _p_float"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (float) SvNV(ST(2)); + + floatP_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_floatArray) { + { + int arg1 ; + floatArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_floatArray(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (floatArray *)new_floatArray(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_floatArray, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_floatArray) { + { + floatArray *arg1 = (floatArray *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_floatArray(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_floatArray,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_floatArray. Expected _p_floatArray"); + } + } + delete_floatArray(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatArray_getitem) { + { + floatArray *arg1 = (floatArray *) 0 ; + int arg2 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: floatArray_getitem(self,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_floatArray,0) < 0) { + SWIG_croak("Type error in argument 1 of floatArray_getitem. Expected _p_floatArray"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (float)floatArray_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatArray_setitem) { + { + floatArray *arg1 = (floatArray *) 0 ; + int arg2 ; + float arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: floatArray_setitem(self,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_floatArray,0) < 0) { + SWIG_croak("Type error in argument 1 of floatArray_setitem. Expected _p_floatArray"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (float) SvNV(ST(2)); + + floatArray_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatArray_cast) { + { + floatArray *arg1 = (floatArray *) 0 ; + float *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: floatArray_cast(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_floatArray,0) < 0) { + SWIG_croak("Type error in argument 1 of floatArray_cast. Expected _p_floatArray"); + } + } + result = (float *)floatArray_cast(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_float, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_floatArray_frompointer) { + { + float *arg1 = (float *) 0 ; + floatArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: floatArray_frompointer(t);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of floatArray_frompointer. Expected _p_float"); + } + } + result = (floatArray *)floatArray_frompointer(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_floatArray, SWIG_SHADOW|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_doubleP) { + { + int arg1 ; + double *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_doubleP(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (double *)new_doubleP(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_double, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_doubleP) { + { + double *arg1 = (double *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_doubleP(ary);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_double,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_doubleP. Expected _p_double"); + } + } + delete_doubleP(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleP_getitem) { + { + double *arg1 = (double *) 0 ; + int arg2 ; + double result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: doubleP_getitem(ary,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_double,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleP_getitem. Expected _p_double"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (double)doubleP_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleP_setitem) { + { + double *arg1 = (double *) 0 ; + int arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: doubleP_setitem(ary,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_double,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleP_setitem. Expected _p_double"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (double) SvNV(ST(2)); + + doubleP_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_doubleArray) { + { + int arg1 ; + doubleArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_doubleArray(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (doubleArray *)new_doubleArray(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_doubleArray, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_doubleArray) { + { + doubleArray *arg1 = (doubleArray *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_doubleArray(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_doubleArray,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_doubleArray. Expected _p_doubleArray"); + } + } + delete_doubleArray(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleArray_getitem) { + { + doubleArray *arg1 = (doubleArray *) 0 ; + int arg2 ; + double result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: doubleArray_getitem(self,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_doubleArray,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleArray_getitem. Expected _p_doubleArray"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (double)doubleArray_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleArray_setitem) { + { + doubleArray *arg1 = (doubleArray *) 0 ; + int arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: doubleArray_setitem(self,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_doubleArray,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleArray_setitem. Expected _p_doubleArray"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (double) SvNV(ST(2)); + + doubleArray_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleArray_cast) { + { + doubleArray *arg1 = (doubleArray *) 0 ; + double *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: doubleArray_cast(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_doubleArray,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleArray_cast. Expected _p_doubleArray"); + } + } + result = (double *)doubleArray_cast(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_double, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_doubleArray_frompointer) { + { + double *arg1 = (double *) 0 ; + doubleArray *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: doubleArray_frompointer(t);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_double,0) < 0) { + SWIG_croak("Type error in argument 1 of doubleArray_frompointer. Expected _p_double"); + } + } + result = (doubleArray *)doubleArray_frompointer(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_doubleArray, SWIG_SHADOW|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_shortP) { + { + int arg1 ; + short *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: new_shortP(nelements);"); + } + arg1 = (int) SvIV(ST(0)); + result = (short *)new_shortP(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_short, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_shortP) { + { + short *arg1 = (short *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_shortP(ary);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_short,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_shortP. Expected _p_short"); + } + } + delete_shortP(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_shortP_getitem) { + { + short *arg1 = (short *) 0 ; + int arg2 ; + short result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: shortP_getitem(ary,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_short,0) < 0) { + SWIG_croak("Type error in argument 1 of shortP_getitem. Expected _p_short"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (short)shortP_getitem(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_shortP_setitem) { + { + short *arg1 = (short *) 0 ; + int arg2 ; + short arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: shortP_setitem(ary,index,value);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_short,0) < 0) { + SWIG_croak("Type error in argument 1 of shortP_setitem. Expected _p_short"); + } + } + arg2 = (int) SvIV(ST(1)); + arg3 = (short) SvIV(ST(2)); + shortP_setitem(arg1,arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cdata) { + { + void *arg1 = (void *) 0 ; + int arg2 ; + SWIGCDATA result; + int argvi = 0; + dXSARGS; + + arg2 = 1; + if ((items < 1) || (items > 2)) { + SWIG_croak("Usage: cdata(ptr,nelements);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, 0,0) < 0) { + SWIG_croak("Type error in argument 1 of cdata. Expected _p_void"); + } + } + if (items > 1) { + arg2 = (int) SvIV(ST(1)); + } + result = cdata_void(arg1,arg2); + + { + ST(argvi) = sv_newmortal(); + sv_setpvn((SV*)ST(argvi++),(&result)->data,(&result)->len); + } + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_memmove) { + { + void *arg1 = (void *) 0 ; + void *arg2 = (void *) 0 ; + int arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: memmove(data,indata,inlen);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, 0,0) < 0) { + SWIG_croak("Type error in argument 1 of memmove. Expected _p_void"); + } + } + { + STRLEN temp; + arg2 = (void *) SvPV(ST(1),temp); + arg3 = (int) temp; + } + memmove(arg1,(void const *)arg2,arg3); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_fold) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) NULL ; + float *arg3 = (float *) 0 ; + char *result; + float temp3 ; + int argvi = 0; + dXSARGS; + + arg3 = &temp3; + if ((items < 1) || (items > 2)) { + SWIG_croak("Usage: fold(string,constraints);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (items > 1) { + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + } + result = (char *)my_fold(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_energy_of_struct) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: energy_of_struct(string,structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (float)energy_of_struct((char const *)arg1,(char const *)arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_free_arrays) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: free_arrays();"); + } + free_arrays(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_initialize_fold) { + { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: initialize_fold(length);"); + } + arg1 = (int) SvIV(ST(0)); + initialize_fold(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_update_fold_params) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: update_fold_params();"); + } + update_fold_params(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cofold) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) NULL ; + float *arg3 = (float *) 0 ; + char *result; + float temp3 ; + int argvi = 0; + dXSARGS; + + arg3 = &temp3; + if ((items < 1) || (items > 2)) { + SWIG_croak("Usage: cofold(string,constraints);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (items > 1) { + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + } + result = (char *)my_cofold(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_free_co_arrays) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: free_co_arrays();"); + } + free_co_arrays(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_initialize_cofold) { + { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: initialize_cofold(length);"); + } + arg1 = (int) SvIV(ST(0)); + initialize_cofold(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_update_cofold_params) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: update_cofold_params();"); + } + update_cofold_params(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_pf_fold) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) NULL ; + float *arg3 = (float *) 0 ; + char *result; + float temp3 ; + int argvi = 0; + dXSARGS; + + arg3 = &temp3; + if ((items < 1) || (items > 2)) { + SWIG_croak("Usage: pf_fold(string,constraints);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (items > 1) { + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + } + result = (char *)my_pf_fold(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_init_pf_fold) { + { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: init_pf_fold(length);"); + } + arg1 = (int) SvIV(ST(0)); + init_pf_fold(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_free_pf_arrays) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: free_pf_arrays();"); + } + free_pf_arrays(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_update_pf_params) { + { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: update_pf_params(length);"); + } + arg1 = (int) SvIV(ST(0)); + update_pf_params(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bppm_symbol) { + { + float *arg1 = (float *) 0 ; + char result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: bppm_symbol(x);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of bppm_symbol. Expected _p_float"); + } + } + result = (char)bppm_symbol((float const *)arg1); + + ST(argvi) = sv_newmortal(); + sv_setpvn((SV*)ST(argvi++), &result, 1); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_mean_bp_dist) { + { + int arg1 ; + double result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: mean_bp_dist(length);"); + } + arg1 = (int) SvIV(ST(0)); + result = (double)mean_bp_dist(arg1); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_pbacktrack) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: pbacktrack(sequence);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)pbacktrack(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_inverse_fold) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + float *arg3 = (float *) 0 ; + char *result; + float temp3 ; + int argvi = 0; + dXSARGS; + + arg3 = &temp3; + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: inverse_fold(start,target);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (char *)my_inverse_fold(arg1,(char const *)arg2,arg3); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_inverse_pf_fold) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + float *arg3 = (float *) 0 ; + char *result; + float temp3 ; + int argvi = 0; + dXSARGS; + + arg3 = &temp3; + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: inverse_pf_fold(start,target);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (char *)my_inverse_pf_fold(arg1,(char const *)arg2,arg3); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bondT_i_set) { + { + bondT *arg1 = (bondT *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: bondT_i_set(self,i);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of bondT_i_set. Expected _p_bond"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->i = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bondT_i_get) { + { + bondT *arg1 = (bondT *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: bondT_i_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of bondT_i_get. Expected _p_bond"); + } + } + result = (int) ((arg1)->i); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bondT_j_set) { + { + bondT *arg1 = (bondT *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: bondT_j_set(self,j);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of bondT_j_set. Expected _p_bond"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->j = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bondT_j_get) { + { + bondT *arg1 = (bondT *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: bondT_j_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of bondT_j_get. Expected _p_bond"); + } + } + result = (int) ((arg1)->j); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bondT_get) { + { + bondT *arg1 = (bondT *) 0 ; + int arg2 ; + bondT *result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: bondT_get(self,i);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of bondT_get. Expected _p_bond"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (bondT *)bondT_get(arg1,arg2); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_bond, SWIG_SHADOW|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_bondT) { + { + bondT *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: new_bondT();"); + } + result = (bondT *)(bondT *) calloc(1, sizeof(bondT)); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_bond, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_bondT) { + { + bondT *arg1 = (bondT *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_bondT(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_bond,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_bondT. Expected _p_bond"); + } + } + free((char *) arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_option_string) { + { + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: option_string();"); + } + result = (char *)option_string(); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_energy_set) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + float arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: SOLUTION_energy_set(self,energy);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_energy_set. Expected _p_SOLUTION"); + } + } + arg2 = (float) SvNV(ST(1)); + + if (arg1) (arg1)->energy = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_energy_get) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: SOLUTION_energy_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_energy_get. Expected _p_SOLUTION"); + } + } + result = (float) ((arg1)->energy); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_structure_set) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + char *arg2 = (char *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: SOLUTION_structure_set(self,structure);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_structure_set. Expected _p_SOLUTION"); + } + } + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + { + if (arg1->structure) free((char*)arg1->structure); + if (arg2) { + arg1->structure = (char *) malloc(strlen(arg2)+1); + strcpy((char*)arg1->structure,arg2); + } else { + arg1->structure = 0; + } + } + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_structure_get) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: SOLUTION_structure_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_structure_get. Expected _p_SOLUTION"); + } + } + result = (char *) ((arg1)->structure); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_get) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + int arg2 ; + SOLUTION *result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: SOLUTION_get(self,i);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_get. Expected _p_SOLUTION"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (SOLUTION *)SOLUTION_get(arg1,arg2); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_SOLUTION, SWIG_SHADOW|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_SOLUTION_size) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: SOLUTION_size(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of SOLUTION_size. Expected _p_SOLUTION"); + } + } + result = (int)SOLUTION_size(arg1); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_SOLUTION) { + { + SOLUTION *arg1 = (SOLUTION *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_SOLUTION(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_SOLUTION,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_SOLUTION. Expected _p_SOLUTION"); + } + } + delete_SOLUTION(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_SOLUTION) { + { + SOLUTION *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: new_SOLUTION();"); + } + result = (SOLUTION *)(SOLUTION *) calloc(1, sizeof(SOLUTION)); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_SOLUTION, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_subopt) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + int arg3 ; + FILE *arg4 = (FILE *) NULL ; + SOLUTION *result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 4)) { + SWIG_croak("Usage: subopt(seq,constraint,delta,fp);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + arg3 = (int) SvIV(ST(2)); + if (items > 3) { + { + if (SvOK(ST(3))) /* check for undef */ + arg4 = PerlIO_findFILE(IoIFP(sv_2io(ST(3)))); + else arg4 = NULL; + } + } + result = (SOLUTION *)subopt(arg1,arg2,arg3,arg4); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_SOLUTION, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_get_pr) { + { + int arg1 ; + int arg2 ; + double result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: get_pr(i,j);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + result = (double)get_pr(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_b2HIT) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: b2HIT(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)b2HIT(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_b2C) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: b2C(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)b2C(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_b2Shapiro) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: b2Shapiro(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)b2Shapiro(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_add_root) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: add_root(char *);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)add_root(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_expand_Shapiro) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: expand_Shapiro(coarse);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)expand_Shapiro(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_expand_Full) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: expand_Full(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)expand_Full(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_unexpand_Full) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: unexpand_Full(ffull);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)unexpand_Full(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_unweight) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: unweight(wcoarse);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)unweight(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_unexpand_aligned_F) { + { + char **arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: unexpand_aligned_F(align);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_p_char,0) < 0) { + SWIG_croak("Type error in argument 1 of unexpand_aligned_F. Expected _p_p_char"); + } + } + unexpand_aligned_F(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_parse_structure) { + { + char *arg1 = (char *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: parse_structure(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + parse_structure(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_make_tree) { + { + char *arg1 = (char *) 0 ; + Tree *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: make_tree(struc);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (Tree *)make_tree(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_Tree, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_tree_edit_distance) { + { + Tree *arg1 = (Tree *) 0 ; + Tree *arg2 = (Tree *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: tree_edit_distance(T1,T2);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_Tree,0) < 0) { + SWIG_croak("Type error in argument 1 of tree_edit_distance. Expected _p_Tree"); + } + } + { + if (SWIG_ConvertPtr(ST(1), (void **) &arg2, SWIGTYPE_p_Tree,0) < 0) { + SWIG_croak("Type error in argument 2 of tree_edit_distance. Expected _p_Tree"); + } + } + result = (float)tree_edit_distance(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_print_tree) { + { + Tree *arg1 = (Tree *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: print_tree(t);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_Tree,0) < 0) { + SWIG_croak("Type error in argument 1 of print_tree. Expected _p_Tree"); + } + } + print_tree(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_free_tree) { + { + Tree *arg1 = (Tree *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: free_tree(t);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_Tree,0) < 0) { + SWIG_croak("Type error in argument 1 of free_tree. Expected _p_Tree"); + } + } + free_tree(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_Make_swString) { + { + char *arg1 = (char *) 0 ; + swString *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: Make_swString(string);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (swString *)Make_swString(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_swString, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_string_edit_distance) { + { + swString *arg1 = (swString *) 0 ; + swString *arg2 = (swString *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: string_edit_distance(T1,T2);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_swString,0) < 0) { + SWIG_croak("Type error in argument 1 of string_edit_distance. Expected _p_swString"); + } + } + { + if (SWIG_ConvertPtr(ST(1), (void **) &arg2, SWIGTYPE_p_swString,0) < 0) { + SWIG_croak("Type error in argument 2 of string_edit_distance. Expected _p_swString"); + } + } + result = (float)string_edit_distance(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_Make_bp_profile) { + { + int arg1 ; + float *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: Make_bp_profile(length);"); + } + arg1 = (int) SvIV(ST(0)); + result = (float *)Make_bp_profile(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_float, 0|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_profile_edit_distance) { + { + float *arg1 = (float *) 0 ; + float *arg2 = (float *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: profile_edit_distance(T1,T2);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of profile_edit_distance. Expected _p_float"); + } + } + { + if (SWIG_ConvertPtr(ST(1), (void **) &arg2, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 2 of profile_edit_distance. Expected _p_float"); + } + } + result = (float)profile_edit_distance((float const *)arg1,(float const *)arg2); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_print_bppm) { + { + float *arg1 = (float *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: print_bppm(T);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of print_bppm. Expected _p_float"); + } + } + print_bppm((float const *)arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_free_profile) { + { + float *arg1 = (float *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: free_profile(T);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_float,0) < 0) { + SWIG_croak("Type error in argument 1 of free_profile. Expected _p_float"); + } + } + free_profile(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_space) { + { + unsigned int arg1 ; + void *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: space(size);"); + } + arg1 = (unsigned int) SvUV(ST(0)); + result = (void *)space(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_void, 0|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_xrealloc) { + { + void *arg1 = (void *) 0 ; + unsigned int arg2 ; + void *result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: xrealloc(p,size);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, 0,0) < 0) { + SWIG_croak("Type error in argument 1 of xrealloc. Expected _p_void"); + } + } + arg2 = (unsigned int) SvUV(ST(1)); + result = (void *)xrealloc(arg1,arg2); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_void, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_nrerror) { + { + char *arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: nrerror(message);"); + } + arg1 = SvPV(ST(0),PL_na); + + nrerror((char const (*))arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_init_rand) { + { + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: init_rand();"); + } + init_rand(); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_urn) { + { + double result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: urn();"); + } + result = (double)urn(); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_int_urn) { + { + int arg1 ; + int arg2 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: int_urn(from,to);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + result = (int)int_urn(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_filecopy) { + { + FILE *arg1 = (FILE *) 0 ; + FILE *arg2 = (FILE *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: filecopy(from,to);"); + } + { + if (SvOK(ST(0))) /* check for undef */ + arg1 = PerlIO_findFILE(IoIFP(sv_2io(ST(0)))); + else arg1 = NULL; + } + { + if (SvOK(ST(1))) /* check for undef */ + arg2 = PerlIO_findFILE(IoIFP(sv_2io(ST(1)))); + else arg2 = NULL; + } + filecopy(arg1,arg2); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_time_stamp) { + { + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: time_stamp();"); + } + result = (char *)time_stamp(); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_random_string) { + { + int arg1 ; + char *arg2 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: random_string(l,symbols);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = SvPV(ST(1),PL_na); + + result = (char *)random_string(arg1,(char const (*))arg2); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_hamming) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: hamming(s1,s2);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (int)hamming((char const *)arg1,(char const *)arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_get_line) { + { + FILE *arg1 = (FILE *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: get_line(fp);"); + } + { + if (SvOK(ST(0))) /* check for undef */ + arg1 = PerlIO_findFILE(IoIFP(sv_2io(ST(0)))); + else arg1 = NULL; + } + result = (char *)get_line((FILE const *)arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_pack_structure) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: pack_structure(struc);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)pack_structure((char const *)arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_unpack_structure) { + { + char *arg1 = (char *) 0 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: unpack_structure(packed);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (char *)unpack_structure((char const *)arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + free(result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_make_pair_table) { + { + char *arg1 = (char *) 0 ; + short *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: make_pair_table(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (short *)make_pair_table((char const *)arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_short, 0|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_bp_distance) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: bp_distance(str1,str2);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (int)bp_distance((char const *)arg1,(char const *)arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_read_parameter_file) { + { + char *arg1 = (char *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: read_parameter_file(fname);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + read_parameter_file(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_write_parameter_file) { + { + char *arg1 = (char *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: write_parameter_file(fname);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + write_parameter_file(arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_deref_any) { + { + void **arg1 = (void **) 0 ; + int arg2 ; + void *result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: deref_any(ptr,index);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_p_void,0) < 0) { + SWIG_croak("Type error in argument 1 of deref_any. Expected _p_p_void"); + } + } + arg2 = (int) SvIV(ST(1)); + result = (void *)deref_any(arg1,arg2); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_void, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_scale_parameters) { + { + paramT *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: scale_parameters();"); + } + result = (paramT *)scale_parameters(); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_paramT, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_copy_parameters) { + { + paramT *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: copy_parameters();"); + } + result = (paramT *)copy_parameters(); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_paramT, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_set_parameters) { + { + paramT *arg1 = (paramT *) 0 ; + paramT *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: set_parameters(dest);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_paramT,0) < 0) { + SWIG_croak("Type error in argument 1 of set_parameters. Expected _p_paramT"); + } + } + result = (paramT *)set_parameters(arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_paramT, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_get_aligned_line) { + { + int arg1 ; + char *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: get_aligned_line(int);"); + } + arg1 = (int) SvIV(ST(0)); + result = (char *)get_aligned_line(arg1); + + ST(argvi) = sv_newmortal(); + if (result) { + sv_setpv((SV*)ST(argvi++), (char *) result); + } else { + sv_setsv((SV*)ST(argvi++), &PL_sv_undef); + } + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_make_loop_index) { + { + char *arg1 = (char *) 0 ; + short *result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: make_loop_index(structure);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (short *)make_loop_index((char const *)arg1); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_short, 0|0); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_energy_of_move) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + int arg3 ; + int arg4 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + SWIG_croak("Usage: energy_of_move(string,structure,mi,mj);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + arg3 = (int) SvIV(ST(2)); + arg4 = (int) SvIV(ST(3)); + result = (float)energy_of_move((char const *)arg1,arg2,arg3,arg4); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_PS_rna_plot) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: PS_rna_plot(string,structure,file);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + result = (int)PS_rna_plot(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_PS_rna_plot_a) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + char *arg4 = (char *) 0 ; + char *arg5 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + SWIG_croak("Usage: PS_rna_plot_a(string,structure,file,pre,post);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + if (!SvOK((SV*) ST(3))) arg4 = 0; + else arg4 = (char *) SvPV(ST(3), PL_na); + if (!SvOK((SV*) ST(4))) arg5 = 0; + else arg5 = (char *) SvPV(ST(4), PL_na); + result = (int)PS_rna_plot_a(arg1,arg2,arg3,arg4,arg5); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_gmlRNA) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + char arg4 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + SWIG_croak("Usage: gmlRNA(string,structure,ssfile,option);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + arg4 = (char) *SvPV(ST(3),PL_na); + result = (int)gmlRNA(arg1,arg2,arg3,arg4); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_ssv_rna_plot) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: ssv_rna_plot(string,structure,ssfile);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + result = (int)ssv_rna_plot(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_svg_rna_plot) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: svg_rna_plot(string,structure,ssfile);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + result = (int)svg_rna_plot(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_xrna_plot) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + char *arg3 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: xrna_plot(string,structure,ssfile);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + result = (int)xrna_plot(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_PS_dot_plot) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: PS_dot_plot(string,file);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + result = (int)PS_dot_plot(arg1,arg2); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_i_set) { + { + cpair *arg1 = (cpair *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_i_set(self,i);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_i_set. Expected _p_cpair"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->i = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_i_get) { + { + cpair *arg1 = (cpair *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_i_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_i_get. Expected _p_cpair"); + } + } + result = (int) ((arg1)->i); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_j_set) { + { + cpair *arg1 = (cpair *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_j_set(self,j);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_j_set. Expected _p_cpair"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->j = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_j_get) { + { + cpair *arg1 = (cpair *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_j_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_j_get. Expected _p_cpair"); + } + } + result = (int) ((arg1)->j); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_mfe_set) { + { + cpair *arg1 = (cpair *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_mfe_set(self,mfe);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_mfe_set. Expected _p_cpair"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->mfe = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_mfe_get) { + { + cpair *arg1 = (cpair *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_mfe_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_mfe_get. Expected _p_cpair"); + } + } + result = (int) ((arg1)->mfe); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_p_set) { + { + cpair *arg1 = (cpair *) 0 ; + float arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_p_set(self,p);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_p_set. Expected _p_cpair"); + } + } + arg2 = (float) SvNV(ST(1)); + + if (arg1) (arg1)->p = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_p_get) { + { + cpair *arg1 = (cpair *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_p_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_p_get. Expected _p_cpair"); + } + } + result = (float) ((arg1)->p); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_hue_set) { + { + cpair *arg1 = (cpair *) 0 ; + float arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_hue_set(self,hue);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_hue_set. Expected _p_cpair"); + } + } + arg2 = (float) SvNV(ST(1)); + + if (arg1) (arg1)->hue = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_hue_get) { + { + cpair *arg1 = (cpair *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_hue_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_hue_get. Expected _p_cpair"); + } + } + result = (float) ((arg1)->hue); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_sat_set) { + { + cpair *arg1 = (cpair *) 0 ; + float arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: cpair_sat_set(self,sat);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_sat_set. Expected _p_cpair"); + } + } + arg2 = (float) SvNV(ST(1)); + + if (arg1) (arg1)->sat = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_cpair_sat_get) { + { + cpair *arg1 = (cpair *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: cpair_sat_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of cpair_sat_get. Expected _p_cpair"); + } + } + result = (float) ((arg1)->sat); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_cpair) { + { + cpair *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: new_cpair();"); + } + result = (cpair *)(cpair *) calloc(1, sizeof(cpair)); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_cpair, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_cpair) { + { + cpair *arg1 = (cpair *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_cpair(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_cpair. Expected _p_cpair"); + } + } + free((char *) arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_PS_color_dot_plot) { + { + char *arg1 = (char *) 0 ; + cpair *arg2 = (cpair *) 0 ; + char *arg3 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + SWIG_croak("Usage: PS_color_dot_plot(string,pi,filename);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + { + if (SWIG_ConvertPtr(ST(1), (void **) &arg2, SWIGTYPE_p_cpair,0) < 0) { + SWIG_croak("Type error in argument 2 of PS_color_dot_plot. Expected _p_cpair"); + } + } + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + result = (int)PS_color_dot_plot(arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_i_set) { + { + plist *arg1 = (plist *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: plist_i_set(self,i);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_i_set. Expected _p_plist"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->i = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_i_get) { + { + plist *arg1 = (plist *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: plist_i_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_i_get. Expected _p_plist"); + } + } + result = (int) ((arg1)->i); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_j_set) { + { + plist *arg1 = (plist *) 0 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: plist_j_set(self,j);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_j_set. Expected _p_plist"); + } + } + arg2 = (int) SvIV(ST(1)); + if (arg1) (arg1)->j = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_j_get) { + { + plist *arg1 = (plist *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: plist_j_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_j_get. Expected _p_plist"); + } + } + result = (int) ((arg1)->j); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_p_set) { + { + plist *arg1 = (plist *) 0 ; + float arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + SWIG_croak("Usage: plist_p_set(self,p);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_p_set. Expected _p_plist"); + } + } + arg2 = (float) SvNV(ST(1)); + + if (arg1) (arg1)->p = arg2; + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_plist_p_get) { + { + plist *arg1 = (plist *) 0 ; + float result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: plist_p_get(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of plist_p_get. Expected _p_plist"); + } + } + result = (float) ((arg1)->p); + + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi++), (double) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_new_plist) { + { + plist *result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + SWIG_croak("Usage: new_plist();"); + } + result = (plist *)(plist *) calloc(1, sizeof(plist)); + + ST(argvi) = sv_newmortal(); + SWIG_MakePtr(ST(argvi++), (void *) result, SWIGTYPE_p_plist, SWIG_SHADOW|SWIG_OWNER); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_delete_plist) { + { + plist *arg1 = (plist *) 0 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + SWIG_croak("Usage: delete_plist(self);"); + } + { + if (SWIG_ConvertPtr(ST(0), (void **) &arg1, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 1 of delete_plist. Expected _p_plist"); + } + } + free((char *) arg1); + + + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + +XS(_wrap_PS_dot_plot_list) { + { + char *arg1 = (char *) 0 ; + char *arg2 = (char *) 0 ; + struct plist *arg3 = (struct plist *) 0 ; + struct plist *arg4 = (struct plist *) 0 ; + char *arg5 = (char *) 0 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + SWIG_croak("Usage: PS_dot_plot_list(string,filename,pl,mf,comment);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + if (!SvOK((SV*) ST(1))) arg2 = 0; + else arg2 = (char *) SvPV(ST(1), PL_na); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 3 of PS_dot_plot_list. Expected _p_plist"); + } + } + { + if (SWIG_ConvertPtr(ST(3), (void **) &arg4, SWIGTYPE_p_plist,0) < 0) { + SWIG_croak("Type error in argument 4 of PS_dot_plot_list. Expected _p_plist"); + } + } + if (!SvOK((SV*) ST(4))) arg5 = 0; + else arg5 = (char *) SvPV(ST(4), PL_na); + result = (int)PS_dot_plot_list(arg1,arg2,arg3,arg4,arg5); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); + fail: + ; + } + croak(Nullch); +} + + + +/* -------- TYPE CONVERSION AND EQUIVALENCE RULES (BEGIN) -------- */ + +static void *_p_floatArrayTo_p_float(void *x) { + return (void *)((float *) ((floatArray *) x)); +} +static void *_p_intArrayTo_p_int(void *x) { + return (void *)((int *) ((intArray *) x)); +} +static void *_p_doubleArrayTo_p_double(void *x) { + return (void *)((double *) ((doubleArray *) x)); +} +static swig_type_info _swigt__p_SOLUTION[] = {{"RNA::SOLUTION", 0, "SOLUTION *", 0, 0, 0, 0},{"RNA::SOLUTION", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_intArray[] = {{"RNA::intArray", 0, "struct intArray *|intArray *", 0, 0, 0, 0},{"RNA::intArray", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_double[] = {{"_p_double", 0, "double *", 0, 0, 0, 0},{"RNA::doubleArray", _p_doubleArrayTo_p_double, 0, 0, 0, 0, 0},{"_p_double", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_bond[] = {{"RNA::bondT", 0, "struct bond *|bondT *", 0, 0, 0, 0},{"RNA::bondT", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_plist[] = {{"RNA::plist", 0, "struct plist *", 0, 0, 0, 0},{"RNA::plist", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_cpair[] = {{"RNA::cpair", 0, "struct cpair *|cpair *", 0, 0, 0, 0},{"RNA::cpair", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_swString[] = {{"_p_swString", 0, "swString *", 0, 0, 0, 0},{"_p_swString", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_float[] = {{"_p_float", 0, "float *", 0, 0, 0, 0},{"_p_float", 0, 0, 0, 0, 0, 0},{"RNA::floatArray", _p_floatArrayTo_p_float, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_void[] = {{"_p_void", 0, "void *", 0, 0, 0, 0},{"_p_void", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_floatArray[] = {{"RNA::floatArray", 0, "struct floatArray *|floatArray *", 0, 0, 0, 0},{"RNA::floatArray", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_doubleArray[] = {{"RNA::doubleArray", 0, "struct doubleArray *|doubleArray *", 0, 0, 0, 0},{"RNA::doubleArray", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_p_void[] = {{"_p_p_void", 0, "void **", 0, 0, 0, 0},{"_p_p_void", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_short[] = {{"_p_short", 0, "short *", 0, 0, 0, 0},{"_p_short", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_p_char[] = {{"_p_p_char", 0, "char **", 0, 0, 0, 0},{"_p_p_char", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_char[] = {{"_p_char", 0, "char *", 0, 0, 0, 0},{"_p_char", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_unsigned_short[] = {{"_p_unsigned_short", 0, "unsigned short *", 0, 0, 0, 0},{"_p_unsigned_short", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_paramT[] = {{"_p_paramT", 0, "paramT *", 0, 0, 0, 0},{"_p_paramT", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_Tree[] = {{"_p_Tree", 0, "Tree *", 0, 0, 0, 0},{"_p_Tree", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_FILE[] = {{"_p_FILE", 0, "FILE *", 0, 0, 0, 0},{"_p_FILE", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; +static swig_type_info _swigt__p_int[] = {{"_p_int", 0, "int *", 0, 0, 0, 0},{"RNA::intArray", _p_intArrayTo_p_int, 0, 0, 0, 0, 0},{"_p_int", 0, 0, 0, 0, 0, 0},{0, 0, 0, 0, 0, 0, 0}}; + +static swig_type_info *swig_types_initial[] = { +_swigt__p_SOLUTION, +_swigt__p_intArray, +_swigt__p_double, +_swigt__p_bond, +_swigt__p_plist, +_swigt__p_cpair, +_swigt__p_swString, +_swigt__p_float, +_swigt__p_void, +_swigt__p_floatArray, +_swigt__p_doubleArray, +_swigt__p_p_void, +_swigt__p_short, +_swigt__p_p_char, +_swigt__p_char, +_swigt__p_unsigned_short, +_swigt__p_paramT, +_swigt__p_Tree, +_swigt__p_FILE, +_swigt__p_int, +0 +}; + + +/* -------- TYPE CONVERSION AND EQUIVALENCE RULES (END) -------- */ + +static swig_constant_info swig_constants[] = { +{ SWIG_FLOAT, (char *) SWIG_prefix "VERSION", 0, (double) 0.3, 0, 0}, +{0,0,0,0,0,0} +}; +#ifdef __cplusplus +} +#endif +static swig_variable_info swig_variables[] = { + { "RNAc::symbolset", MAGIC_CLASS _wrap_set_symbolset, MAGIC_CLASS _wrap_val_symbolset,0 }, + { "RNAc::final_cost", MAGIC_CLASS _wrap_set_final_cost, MAGIC_CLASS _wrap_val_final_cost,0 }, + { "RNAc::give_up", MAGIC_CLASS _wrap_set_give_up, MAGIC_CLASS _wrap_val_give_up,0 }, + { "RNAc::noGU", MAGIC_CLASS _wrap_set_noGU, MAGIC_CLASS _wrap_val_noGU,0 }, + { "RNAc::no_closingGU", MAGIC_CLASS _wrap_set_no_closingGU, MAGIC_CLASS _wrap_val_no_closingGU,0 }, + { "RNAc::tetra_loop", MAGIC_CLASS _wrap_set_tetra_loop, MAGIC_CLASS _wrap_val_tetra_loop,0 }, + { "RNAc::energy_set", MAGIC_CLASS _wrap_set_energy_set, MAGIC_CLASS _wrap_val_energy_set,0 }, + { "RNAc::dangles", MAGIC_CLASS _wrap_set_dangles, MAGIC_CLASS _wrap_val_dangles,0 }, + { "RNAc::nonstandards", MAGIC_CLASS _wrap_set_nonstandards, MAGIC_CLASS _wrap_val_nonstandards,0 }, + { "RNAc::temperature", MAGIC_CLASS _wrap_set_temperature, MAGIC_CLASS _wrap_val_temperature,0 }, + { "RNAc::james_rule", MAGIC_CLASS _wrap_set_james_rule, MAGIC_CLASS _wrap_val_james_rule,0 }, + { "RNAc::logML", MAGIC_CLASS _wrap_set_logML, MAGIC_CLASS _wrap_val_logML,0 }, + { "RNAc::cut_point", MAGIC_CLASS _wrap_set_cut_point, MAGIC_CLASS _wrap_val_cut_point,0 }, + { "RNAc::base_pair", MAGIC_CLASS _wrap_set_base_pair, MAGIC_CLASS _wrap_val_base_pair,&SWIGTYPE_p_bond }, + { "RNAc::pr", MAGIC_CLASS _wrap_set_pr, MAGIC_CLASS _wrap_val_pr,&SWIGTYPE_p_double }, + { "RNAc::iindx", MAGIC_CLASS _wrap_set_iindx, MAGIC_CLASS _wrap_val_iindx,&SWIGTYPE_p_int }, + { "RNAc::pf_scale", MAGIC_CLASS _wrap_set_pf_scale, MAGIC_CLASS _wrap_val_pf_scale,0 }, + { "RNAc::fold_constrained", MAGIC_CLASS _wrap_set_fold_constrained, MAGIC_CLASS _wrap_val_fold_constrained,0 }, + { "RNAc::do_backtrack", MAGIC_CLASS _wrap_set_do_backtrack, MAGIC_CLASS _wrap_val_do_backtrack,0 }, + { "RNAc::noLonelyPairs", MAGIC_CLASS _wrap_set_noLonelyPairs, MAGIC_CLASS _wrap_val_noLonelyPairs,0 }, + { "RNAc::backtrack_type", MAGIC_CLASS _wrap_set_backtrack_type, MAGIC_CLASS _wrap_val_backtrack_type,0 }, + { "RNAc::subopt_sorted", MAGIC_CLASS _wrap_set_subopt_sorted, MAGIC_CLASS _wrap_val_subopt_sorted,0 }, + { "RNAc::loop_size", MAGIC_CLASS _wrap_set_loop_size, MAGIC_CLASS _wrap_val_loop_size,&SWIGTYPE_p_int }, + { "RNAc::helix_size", MAGIC_CLASS _wrap_set_helix_size, MAGIC_CLASS _wrap_val_helix_size,&SWIGTYPE_p_int }, + { "RNAc::loop_degree", MAGIC_CLASS _wrap_set_loop_degree, MAGIC_CLASS _wrap_val_loop_degree,&SWIGTYPE_p_int }, + { "RNAc::loops", MAGIC_CLASS _wrap_set_loops, MAGIC_CLASS _wrap_val_loops,0 }, + { "RNAc::unpaired", MAGIC_CLASS _wrap_set_unpaired, MAGIC_CLASS _wrap_val_unpaired,0 }, + { "RNAc::pairs", MAGIC_CLASS _wrap_set_pairs, MAGIC_CLASS _wrap_val_pairs,0 }, + { "RNAc::edit_backtrack", MAGIC_CLASS _wrap_set_edit_backtrack, MAGIC_CLASS _wrap_val_edit_backtrack,0 }, + { "RNAc::aligned_line", MAGIC_CLASS _wrap_set_aligned_line, MAGIC_CLASS _wrap_val_aligned_line,&SWIGTYPE_p_p_char }, + { "RNAc::cost_matrix", MAGIC_CLASS _wrap_set_cost_matrix, MAGIC_CLASS _wrap_val_cost_matrix,0 }, + { "RNAc::xsubi", MAGIC_CLASS _wrap_set_xsubi, MAGIC_CLASS _wrap_val_xsubi,&SWIGTYPE_p_unsigned_short }, + { "RNAc::rna_plot_type", MAGIC_CLASS _wrap_set_rna_plot_type, MAGIC_CLASS _wrap_val_rna_plot_type,0 }, +{0,0,0,0} +}; +static swig_command_info swig_commands[] = { +{"RNAc::new_intP", _wrap_new_intP}, +{"RNAc::delete_intP", _wrap_delete_intP}, +{"RNAc::intP_getitem", _wrap_intP_getitem}, +{"RNAc::intP_setitem", _wrap_intP_setitem}, +{"RNAc::new_intArray", _wrap_new_intArray}, +{"RNAc::delete_intArray", _wrap_delete_intArray}, +{"RNAc::intArray_getitem", _wrap_intArray_getitem}, +{"RNAc::intArray_setitem", _wrap_intArray_setitem}, +{"RNAc::intArray_cast", _wrap_intArray_cast}, +{"RNAc::intArray_frompointer", _wrap_intArray_frompointer}, +{"RNAc::new_floatP", _wrap_new_floatP}, +{"RNAc::delete_floatP", _wrap_delete_floatP}, +{"RNAc::floatP_getitem", _wrap_floatP_getitem}, +{"RNAc::floatP_setitem", _wrap_floatP_setitem}, +{"RNAc::new_floatArray", _wrap_new_floatArray}, +{"RNAc::delete_floatArray", _wrap_delete_floatArray}, +{"RNAc::floatArray_getitem", _wrap_floatArray_getitem}, +{"RNAc::floatArray_setitem", _wrap_floatArray_setitem}, +{"RNAc::floatArray_cast", _wrap_floatArray_cast}, +{"RNAc::floatArray_frompointer", _wrap_floatArray_frompointer}, +{"RNAc::new_doubleP", _wrap_new_doubleP}, +{"RNAc::delete_doubleP", _wrap_delete_doubleP}, +{"RNAc::doubleP_getitem", _wrap_doubleP_getitem}, +{"RNAc::doubleP_setitem", _wrap_doubleP_setitem}, +{"RNAc::new_doubleArray", _wrap_new_doubleArray}, +{"RNAc::delete_doubleArray", _wrap_delete_doubleArray}, +{"RNAc::doubleArray_getitem", _wrap_doubleArray_getitem}, +{"RNAc::doubleArray_setitem", _wrap_doubleArray_setitem}, +{"RNAc::doubleArray_cast", _wrap_doubleArray_cast}, +{"RNAc::doubleArray_frompointer", _wrap_doubleArray_frompointer}, +{"RNAc::new_shortP", _wrap_new_shortP}, +{"RNAc::delete_shortP", _wrap_delete_shortP}, +{"RNAc::shortP_getitem", _wrap_shortP_getitem}, +{"RNAc::shortP_setitem", _wrap_shortP_setitem}, +{"RNAc::cdata", _wrap_cdata}, +{"RNAc::memmove", _wrap_memmove}, +{"RNAc::fold", _wrap_fold}, +{"RNAc::energy_of_struct", _wrap_energy_of_struct}, +{"RNAc::free_arrays", _wrap_free_arrays}, +{"RNAc::initialize_fold", _wrap_initialize_fold}, +{"RNAc::update_fold_params", _wrap_update_fold_params}, +{"RNAc::cofold", _wrap_cofold}, +{"RNAc::free_co_arrays", _wrap_free_co_arrays}, +{"RNAc::initialize_cofold", _wrap_initialize_cofold}, +{"RNAc::update_cofold_params", _wrap_update_cofold_params}, +{"RNAc::pf_fold", _wrap_pf_fold}, +{"RNAc::init_pf_fold", _wrap_init_pf_fold}, +{"RNAc::free_pf_arrays", _wrap_free_pf_arrays}, +{"RNAc::update_pf_params", _wrap_update_pf_params}, +{"RNAc::bppm_symbol", _wrap_bppm_symbol}, +{"RNAc::mean_bp_dist", _wrap_mean_bp_dist}, +{"RNAc::pbacktrack", _wrap_pbacktrack}, +{"RNAc::inverse_fold", _wrap_inverse_fold}, +{"RNAc::inverse_pf_fold", _wrap_inverse_pf_fold}, +{"RNAc::bondT_i_set", _wrap_bondT_i_set}, +{"RNAc::bondT_i_get", _wrap_bondT_i_get}, +{"RNAc::bondT_j_set", _wrap_bondT_j_set}, +{"RNAc::bondT_j_get", _wrap_bondT_j_get}, +{"RNAc::bondT_get", _wrap_bondT_get}, +{"RNAc::new_bondT", _wrap_new_bondT}, +{"RNAc::delete_bondT", _wrap_delete_bondT}, +{"RNAc::option_string", _wrap_option_string}, +{"RNAc::SOLUTION_energy_set", _wrap_SOLUTION_energy_set}, +{"RNAc::SOLUTION_energy_get", _wrap_SOLUTION_energy_get}, +{"RNAc::SOLUTION_structure_set", _wrap_SOLUTION_structure_set}, +{"RNAc::SOLUTION_structure_get", _wrap_SOLUTION_structure_get}, +{"RNAc::SOLUTION_get", _wrap_SOLUTION_get}, +{"RNAc::SOLUTION_size", _wrap_SOLUTION_size}, +{"RNAc::delete_SOLUTION", _wrap_delete_SOLUTION}, +{"RNAc::new_SOLUTION", _wrap_new_SOLUTION}, +{"RNAc::subopt", _wrap_subopt}, +{"RNAc::get_pr", _wrap_get_pr}, +{"RNAc::b2HIT", _wrap_b2HIT}, +{"RNAc::b2C", _wrap_b2C}, +{"RNAc::b2Shapiro", _wrap_b2Shapiro}, +{"RNAc::add_root", _wrap_add_root}, +{"RNAc::expand_Shapiro", _wrap_expand_Shapiro}, +{"RNAc::expand_Full", _wrap_expand_Full}, +{"RNAc::unexpand_Full", _wrap_unexpand_Full}, +{"RNAc::unweight", _wrap_unweight}, +{"RNAc::unexpand_aligned_F", _wrap_unexpand_aligned_F}, +{"RNAc::parse_structure", _wrap_parse_structure}, +{"RNAc::make_tree", _wrap_make_tree}, +{"RNAc::tree_edit_distance", _wrap_tree_edit_distance}, +{"RNAc::print_tree", _wrap_print_tree}, +{"RNAc::free_tree", _wrap_free_tree}, +{"RNAc::Make_swString", _wrap_Make_swString}, +{"RNAc::string_edit_distance", _wrap_string_edit_distance}, +{"RNAc::Make_bp_profile", _wrap_Make_bp_profile}, +{"RNAc::profile_edit_distance", _wrap_profile_edit_distance}, +{"RNAc::print_bppm", _wrap_print_bppm}, +{"RNAc::free_profile", _wrap_free_profile}, +{"RNAc::space", _wrap_space}, +{"RNAc::xrealloc", _wrap_xrealloc}, +{"RNAc::nrerror", _wrap_nrerror}, +{"RNAc::init_rand", _wrap_init_rand}, +{"RNAc::urn", _wrap_urn}, +{"RNAc::int_urn", _wrap_int_urn}, +{"RNAc::filecopy", _wrap_filecopy}, +{"RNAc::time_stamp", _wrap_time_stamp}, +{"RNAc::random_string", _wrap_random_string}, +{"RNAc::hamming", _wrap_hamming}, +{"RNAc::get_line", _wrap_get_line}, +{"RNAc::pack_structure", _wrap_pack_structure}, +{"RNAc::unpack_structure", _wrap_unpack_structure}, +{"RNAc::make_pair_table", _wrap_make_pair_table}, +{"RNAc::bp_distance", _wrap_bp_distance}, +{"RNAc::read_parameter_file", _wrap_read_parameter_file}, +{"RNAc::write_parameter_file", _wrap_write_parameter_file}, +{"RNAc::deref_any", _wrap_deref_any}, +{"RNAc::scale_parameters", _wrap_scale_parameters}, +{"RNAc::copy_parameters", _wrap_copy_parameters}, +{"RNAc::set_parameters", _wrap_set_parameters}, +{"RNAc::get_aligned_line", _wrap_get_aligned_line}, +{"RNAc::make_loop_index", _wrap_make_loop_index}, +{"RNAc::energy_of_move", _wrap_energy_of_move}, +{"RNAc::PS_rna_plot", _wrap_PS_rna_plot}, +{"RNAc::PS_rna_plot_a", _wrap_PS_rna_plot_a}, +{"RNAc::gmlRNA", _wrap_gmlRNA}, +{"RNAc::ssv_rna_plot", _wrap_ssv_rna_plot}, +{"RNAc::svg_rna_plot", _wrap_svg_rna_plot}, +{"RNAc::xrna_plot", _wrap_xrna_plot}, +{"RNAc::PS_dot_plot", _wrap_PS_dot_plot}, +{"RNAc::cpair_i_set", _wrap_cpair_i_set}, +{"RNAc::cpair_i_get", _wrap_cpair_i_get}, +{"RNAc::cpair_j_set", _wrap_cpair_j_set}, +{"RNAc::cpair_j_get", _wrap_cpair_j_get}, +{"RNAc::cpair_mfe_set", _wrap_cpair_mfe_set}, +{"RNAc::cpair_mfe_get", _wrap_cpair_mfe_get}, +{"RNAc::cpair_p_set", _wrap_cpair_p_set}, +{"RNAc::cpair_p_get", _wrap_cpair_p_get}, +{"RNAc::cpair_hue_set", _wrap_cpair_hue_set}, +{"RNAc::cpair_hue_get", _wrap_cpair_hue_get}, +{"RNAc::cpair_sat_set", _wrap_cpair_sat_set}, +{"RNAc::cpair_sat_get", _wrap_cpair_sat_get}, +{"RNAc::new_cpair", _wrap_new_cpair}, +{"RNAc::delete_cpair", _wrap_delete_cpair}, +{"RNAc::PS_color_dot_plot", _wrap_PS_color_dot_plot}, +{"RNAc::plist_i_set", _wrap_plist_i_set}, +{"RNAc::plist_i_get", _wrap_plist_i_get}, +{"RNAc::plist_j_set", _wrap_plist_j_set}, +{"RNAc::plist_j_get", _wrap_plist_j_get}, +{"RNAc::plist_p_set", _wrap_plist_p_set}, +{"RNAc::plist_p_get", _wrap_plist_p_get}, +{"RNAc::new_plist", _wrap_new_plist}, +{"RNAc::delete_plist", _wrap_delete_plist}, +{"RNAc::PS_dot_plot_list", _wrap_PS_dot_plot_list}, +{0,0} +}; + + +static void SWIG_Perl_SetTypeListHandle(swig_type_info **handle) { + SV *pointer; + + /* create a new pointer */ + pointer = get_sv("swig_runtime_data::type_pointer" SWIG_RUNTIME_VERSION SWIG_TYPE_TABLE_NAME, TRUE); + sv_setiv(pointer, PTR2IV(swig_type_list_handle)); +} + +static swig_type_info ** +SWIG_Perl_LookupTypePointer(swig_type_info **type_list_handle) { + swig_type_info **type_pointer; + + /* first check if module already created */ + type_pointer = SWIG_Perl_GetTypeListHandle(); + if (type_pointer) { + return type_pointer; + } else { + /* create a new module and variable */ + SWIG_Perl_SetTypeListHandle(type_list_handle); + return type_list_handle; + } +} + + +#ifdef __cplusplus +extern "C" +#endif + +XS(SWIG_init) { + dXSARGS; + int i; + static int _init = 0; + if (!_init) { + swig_type_list_handle = SWIG_Perl_LookupTypePointer(swig_type_list_handle); + for (i = 0; swig_types_initial[i]; i++) { + swig_types[i] = SWIG_TypeRegister(swig_types_initial[i]); + } + _init = 1; + } + + /* Install commands */ + for (i = 0; swig_commands[i].name; i++) { + newXS((char*) swig_commands[i].name,swig_commands[i].wrapper, (char*)__FILE__); + } + + /* Install variables */ + for (i = 0; swig_variables[i].name; i++) { + SV *sv; + sv = perl_get_sv((char*) swig_variables[i].name, TRUE | 0x2); + if (swig_variables[i].type) { + SWIG_MakePtr(sv,(void *)1, *swig_variables[i].type,0); + } else { + sv_setiv(sv,(IV) 0); + } + swig_create_magic(sv, (char *) swig_variables[i].name, swig_variables[i].set, swig_variables[i].get); + } + + /* Install constant */ + for (i = 0; swig_constants[i].type; i++) { + SV *sv; + sv = perl_get_sv((char*)swig_constants[i].name, TRUE | 0x2); + switch(swig_constants[i].type) { + case SWIG_INT: + sv_setiv(sv, (IV) swig_constants[i].lvalue); + break; + case SWIG_FLOAT: + sv_setnv(sv, (double) swig_constants[i].dvalue); + break; + case SWIG_STRING: + sv_setpv(sv, (char *) swig_constants[i].pvalue); + break; + case SWIG_POINTER: + SWIG_MakePtr(sv, swig_constants[i].pvalue, *(swig_constants[i].ptype),0); + break; + case SWIG_BINARY: + SWIG_MakePackedObj(sv, swig_constants[i].pvalue, swig_constants[i].lvalue, *(swig_constants[i].ptype)); + break; + default: + break; + } + SvREADONLY_on(sv); + } + + SWIG_TypeClientData(SWIGTYPE_p_intArray, (void*) "RNA::intArray"); + SWIG_TypeClientData(SWIGTYPE_p_floatArray, (void*) "RNA::floatArray"); + SWIG_TypeClientData(SWIGTYPE_p_doubleArray, (void*) "RNA::doubleArray"); + SWIG_TypeClientData(SWIGTYPE_p_bond, (void*) "RNA::bondT"); + SWIG_TypeClientData(SWIGTYPE_p_SOLUTION, (void*) "RNA::SOLUTION"); + + /* work around segfault when script tries to free symbolset */ + + symbolset = (char *) space(21); + strcpy(symbolset, "AUGC"); + + + SWIG_TypeClientData(SWIGTYPE_p_cpair, (void*) "RNA::cpair"); + SWIG_TypeClientData(SWIGTYPE_p_plist, (void*) "RNA::plist"); + ST(0) = &PL_sv_yes; + XSRETURN(1); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA_wrap.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNA_wrap.o new file mode 100755 index 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zBIrHn{jIJaO`l5NYW+Q;pQZoLYMlr4=k)hh>%`qDb)FfP8E71dMm4Sy3za7 zhgq#NnLdZU-D;iR>F4QprN57lJ=XUzY?svjv8_KZGUgXyp|l?B`2IypiM?0qJc+E%Q^@M`Uzy&J-qLEFuJnHNp;qfmqR*ypw_4{n`Z@Yv zR_pvje?brZ8m#k?)p?Ryou`P^I#ub7>22hPUmrd8uaC@+W`2t2OY7H1kNxYT^{^C>!>^C-+V6qYeow7`ecTuHcvd~B)%(mu&rL66{p%yW5xtew^%Lkb=?m$<(to3$ zp}(WY*ss@X-*{H*l(1X%^UdnKb(wE!^?mF}|Caup)$1nH=g^nXH_~^}&su#SuhQ?+ zpIHC;ctC33I9BIMXtjPJdTDw%y&b(Py^qy%A3>i)pJ}zuX8JGmgY?_#K zI!}75^JKSLzc9TFy^_`XZRy|8d()@W7t&YK57ST4FIlaBhyIxU+G_nIhosJv*6KW2 zt$H}U7QK38LaUmrd8ua8Hh_K$7-d66;8=+{S&{p+Lk zuaEM>uaEM>uaE9}T}P|e^|1c+kv@Sw-RgWx>FelQt$%%_|4F}Yb$z^}QtKzPT0fmt zFGH_FuTAe~x9PbsKb848R^Pi-^v(2LR_pyizeK-A|BwEfp75Bi*Y_@s)w!}+ohz@^ z`z}Qfr`NPvzYDz&eK37KeIfbc4^JKL;Pado5E7R-H zn^>*if!>oo!0P&$^u_em^ds~O^ea~DJfy#(NBTWjC!Y0lvpP>9tIuI2dTn}R>+{fi z(g#?bXAFHBeXI5Ni++}VUHbFON>{=JgN`aEa1`aBnr{ydkG z{ycx>u5&lGdR=R)=h~A#kUqldeADRj>C3G?&wJ^|=%=l&51o)&KbG~mta>Kte=lE- z`D)D9WxgkUAbkXV8ht)}qt(C1JVZZ9zi9P7ZqpypUs>({=^s+(N^f

      Vienna RNA Secondary Structure Prediction

      \n"; + print "

      ", + "A web interface to the RNAfold programm

      \n"; + + print "This server will predict secondary structures of single stranded\n", + "RNA or DNA sequences. If the options look confusing read the\n", + "", + "help page

      \n"; + + print "News: based on ViennaRNA-1.5
      \n", + "Try the new SVG plot if your browser supports it!\n

      \n"; + &print_prompt($query); +} + +sub print_prompt { + my($query) = @_; + + print $query->startform(-action=>'/cgi-bin/RNAfold.cgi#Results'); + print "Name of sequence ", + "(choose a unique identifier)
      \n> "; + print $query->textfield('name'); + + + print "

      \nType in your sequence\nTs will be ", + "automatically replaced by Us.\nAny symbols except ", + "AUCGTXKI will be interpreted as nonbonding bases. ", + "Maximum sequence length is currently $maxlength
      \n"; + + print $query->textarea(-name=>'Sequence', + -rows=>5, + -columns=>70, + -default=>""); + + print "

      \nChoose Fold Algorithm
      \n"; + + print $query->popup_menu(-name => 'pffold', + -values => ['mfe','pf'], + -default => 'pf', + -labels => {'mfe', 'minimum free energy only', + 'pf', + 'partition function and pair probabilities'} + ); + print $query->popup_menu(-name => 'Params', + -values => ['RNA','oldRNA','DNA'], + -default => 'RNA', + -labels => {'RNA', 'use RNA parameters', + 'oldRNA', 'old RNA parameters', + 'DNA', 'use DNA parameters'} + ); + + print "

      Options to modify the fold algorithm

      \n"; + print "Rescale energy parameters to temperature\n", + $query->textfield(-name=>'Temp', + -default=>37, + -size=>3); + print "C

      \n"; + print $query->checkbox_group( + -name=>'toggles', + -values=>['-4', '-d', '-noGU', '-noCloseGU', + '-noLP'], + -labels=>{'-4', 'no special tetraloops', + '-d', 'no dangling end energies', + '-noGU', 'no GU pairs', + '-noCloseGU', + 'no GU pairs at the end of helices', + '-noLP', 'avoid isolated base pairs' + }, + -linebreak=>'yes', + -defaults=>[]); + + print "\n
      ", + "Should we produce a mountain plot of the structure? \n", + $query->checkbox(-name=>'plot', -checked=>'ON'); + print "\n
      View a plot of the mfe structure inline using\n", + "an SVG image (may requires plugin)\n", + $query->checkbox(-name=>'SVG', checked=>'ON'); + print "
      \nor using the SStructView java applet?\n", + $query->checkbox(-name=>'SSview'); + + print "

      \n",$query->reset, "\n"; + print $query->submit('Action','Fold it'), "\n"; + print $query->endform, "\n"; + + if (!$query->param) { + my @old_files = $query->cookie('old_files'); + if (@old_files) { + print "

      The results from your last run should still be in\n"; + foreach my $f (@old_files) { + print " $f"; + } + print ".\n"; + } + } + print "

      \n"; +} + +sub do_work { +# setpriority(PRIO_PROCESS, 0, 19); + my($query) = @_; + my($OK_CHARS) = '-a-zA-Z0-9_.@ '; + my($RNAfold_id, $junk); + my($WORK_DIR) = $serverroot . $hdir; + my($sfact) = 1.02; + chdir $WORK_DIR || die("can't change directory"); + + # clean old files + foreach my $f (< *.ps *.png *.coords *.svg>) { + unlink($f) if (-M $f)>1.5; + } + + my $Sequence = $query->param('Sequence'); + if (length($Sequence) < 1) { # do nothing + &print_header($query); + return; + } + $Sequence =~ s/[\n\s]//gm; # remove whitespace and linebreaks + $Sequence = uc $Sequence; # upper case + if ($query->param('Params') eq 'DNA') { + $Sequence =~ s/U/T/g; # U -> T + } else { + $Sequence =~ s/T/U/g; # T -> U + } + + my $name = $query->param('name'); + + my $options = ""; + $options .= " -p" if ($query->param('pffold') eq 'pf'); + $options .= " -P dna.par" if $query->param('Params') eq 'DNA'; + $options .= " -P vienna13.par" if $query->param('Params') eq 'oldRNA'; + $options .= " " . join(' ', $query->param('toggles')); + $RNA::tetra_loop = 0 if $options =~ /-4/; + $RNA::dangles = 0 if $options =~ /-d/; + $RNA::noGU = 1 if $options =~ /-noGU/; + $RNA::no_closingGU = 1 if $options =~ /-noCloseGU/; + $RNA::noLonelyPairs = 1 if $options =~ /-noLP/; + + if ($query->param('Temp') =~ /([-+]?\d+\.?\d*)/) { + $RNA::temperature = $1; + $options .= " -T $1" if $1 != 37; + } + + # remove strange characters, so we can pass strings to shell + $options =~ s/[^$OK_CHARS]//go; + if ($name =~ /(\S+)/) { + $name = $1; + } else { + $name = "s$$"; + } + + $name =~ s/\///g; # no / allowed in file names + my $fname_ss = $name . "_ss.ps"; + my $fname_dp = ($options =~ /-p /)?($name . "_dp.ps"):""; + my $fname_co = $name . ".coords"; + my $fname_svg = $name . ".svg"; + my $ss_escaped = uri_escape($fname_ss); + my $dp_escaped = uri_escape($fname_dp); + my $png_escaped = uri_escape($name . ".png"); + + my $the_cookie = $query->cookie(-name=>'old_files', + -value=>[$ss_escaped,$dp_escaped,$png_escaped], + -expires=>'+1d', + -path=>'/cgi-bin'); + + &print_header($query, $the_cookie); # don't print anything before this line + + print "

      Here are your results

      \n"; + + if ($query->param('Params') eq 'DNA') { + print "DNA parameters provided by courtesy of " . + "", + "John SantaLucia Jr.
      \n", + "In any publication using these relsults, please cite:
      \n", + "SantaLucia, J Jr (1998) ", + "\"A unified view of polymer, dumbbell, and oligonucleotide DNA ", + "nearest-neighbor thermodynamics.\"\n", + "Proc. Natl. Acad. Sci. USA 95, 1460-1465.\n", + "

      \n"; + } else { + print "RNA parameters are described in
      \n" . + "D.H. Mathews, J. Sabina, M. Zucker and H. Turner\n", + "\"Expanded Sequence Dependence of Thermodynamic Parameters ", + "Provides Robust Prediction of RNA Secondary Structure\",\n", + "JMB, 288, pp 911-940, 1999
      \n"; + } +# print $query->query_string, "
      \n"; + my $length = length($Sequence); + if ($length > $maxlength) { + print "Sorry, this interface is still being tested.\n", + "Currently, sequences longer than $maxlength bases will currently ", + "not be processed. Your sequence has length $length.
      \n"; + return; + } + + print "An equivalent RNAfold command line would have been
      \n"; + print "RNAfold $options

      \n"; + if ($query->param('Params') eq 'DNA') { + RNA::read_parameter_file("$paramdir/dna.par"); + } elsif ($query->param('Params') eq 'oldRNA') { + RNA::read_parameter_file("$paramdir/vienna13.par"); + } + + my ($structure, $mfe) = RNA::fold($Sequence); + print "The optimal secondary structure in bracket notation is given below\n"; + my $eseq = $Sequence; + encode_entities($eseq); + + print "

      \n";
+   print "> $name\n$eseq\n$structure";
+   printf " (%6.2f)\n", $mfe;
+   print "

      \n"; + print "The minimum free energy in kcal/mol is given in parenthesis.\n"; + + if (!($structure =~ /\(/)) {$RNA::rna_plot_type = 0}; + RNA::PS_rna_plot($Sequence, $structure, $fname_ss); + print "You may look at the PostScript drawing of the structure\n"; + my $efname = $fname_ss; encode_entities($efname); + print "in $efname.

      \n"; + + if ($options =~ /-p/) { + $RNA::dangles = 2 if $RNA::dangles; + my $min_en = RNA::energy_of_struct($Sequence, $structure); + my $kT = ($RNA::temperature+273.15)*1.98717/1000.; # in Kcal + $RNA::pf_scale = exp(-($sfact*$min_en)/$kT/$length); + my ($pf_struct, $energy) = RNA::pf_fold($Sequence); + print "The free energy of the thermodynamic ensemble is "; + printf "%6.2f kcal/mol\n", $energy; + RNA::PS_dot_plot($Sequence, $fname_dp); + print "
      The PostScript dot plot containing the base pair ", + "probabilities is in\n", + encode_entities($fname_dp), ".\n"; + } + print "

      "; + + mountain($name, $structure, $options) if $query->param('plot') eq 'on'; + + if ($query->param('SSview') eq 'on') { + my $ret = RNA::ssv_rna_plot($Sequence, $structure, $fname_co); + if ($ret == 0) { + print "error: ssv_rna_plot plot failed, sorry

      \n"; + return; + } + my $escaped = uri_escape($fname_co); + print "Please be patient while the applet is loading
      \n"; + print "\n", + "\n", + "\n", +# "\n", + "\n", + "
      \n"; + print "For information on the java applet see the ", + "SStructView home page

      \n"; + } + + if ($query->param('SVG') eq 'on') { + my $ret = RNA::svg_rna_plot($Sequence, $structure, $fname_svg); + if ($ret == 0) { + print "error: svg_rna_plot plot failed, sorry

      \n"; + return; + } + my $escaped = uri_escape($fname_svg); + print "
      \n"; + print 'Note: you need the ', + "Adobe SVG plugin or an SVG enabled browser to view the graphics
      \n"; + } + + print "Your output files will be deleted from this server after one day.\n"; + +# $myself = $query->self_url; +# print "
      Back to the input form"; + print "
      Scroll back to the top to submit another sequence.\n"; + + my ($user,$system,$cuser,$csystem) = times; + print "
      Time used for this call ",$user+$system, " seconds\n"; + print "
      \n"; +} + +sub print_tail { + print <Ivo Hofacker + <ivo\@tbi.univie.ac.at> +
      + Vienna RNA Home Page +END +} + +sub mountain { + my($name, $structure, $options) = @_; + my $length = length $structure; + my $width = 480; + my $height = 300; + + # FIXME: legend_lables when doing mfe only + my $skip = 10**(int (log($length)/log(10.) - 0.5)); + my $obj = Chart::Lines->new( $width, $height ); + $obj->set ('title' => $name, + 'x_label' => 'Position', + 'y_label' => 'Height', + 'min_val' => 0, + 'legend_labels' => ['mfe'], + 'skip_x_ticks' => $skip); + + $obj->add_dataset ((0..$length)); + + #my $bp = $RNA::base_pair; + #my $npair = RNA::bond_i_get($bp); + my @mp = (0); # valid indices 1..length + my $h = 0; + foreach (split(//, $structure)) { + $h-- if $_ eq ')'; + push @mp, $h; + $h++ if $_ eq '('; + } + warn "illegal structure $structure" if $mp[-1] != 0; + $obj->add_dataset (@mp[0..$length]); # @mp[1..$length] ?? + + if ($options =~ /-p/) { # we have base pairing probs + $obj->set('legend_labels' => ['mfe', 'pf']); + my $bpp = RNA::Make_bp_profile($length); + my @bpp = unpack("f*",RNA::cdata($bpp, ($length+1)*4*3)); + $mp[0] = $mp[1] = 0; # use indices [1..length] + for my $i (1..$length) { + $mp[$i] -= $bpp[$i*3+2]; # paired downstream + $mp[$i+1] = $mp[$i] + $bpp[$i*3+1]; # upstream + } + + $obj->add_dataset (@mp[0..$length]); + } + + $name .= ".png"; + $obj->png("$name"); + my $png_escaped = uri_escape($name); + print "\"Mountain

      \n"; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNAfold.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNAfold.pl new file mode 100755 index 00000000..b719d022 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNAfold.pl @@ -0,0 +1,141 @@ +#!/usr/bin/perl +# -*-Perl-*- +# Last changed Time-stamp: <2003-02-03 18:27:19 ivo> + +use RNA; +use Getopt::Long; +use strict; +use warnings; + + Getopt::Long::config("no_ignore_case"); + +use vars qw/$opt_debug $opt_v $ParamFile $pf $ns_bases/; +my $sfact=1.07; +&usage() unless GetOptions("p|p1" => \$pf, + "p0" => sub {$pf=1; $RNA::do_backtrack=0}, + "C" => \$RNA::fold_constrained, + "T=f" => \$RNA::temperature, + "4" => sub {$RNA::tetra_loop = 0}, + "d|d0" => sub {$RNA::dangles=0}, + "d2" => sub {$RNA::dangles=2},, + "noGU" => \$RNA::noGU, + "noCloseGU" => \$RNA::no_closingGU, + "noLP" => \$RNA::noLonelyPairs, + "e=i" => \$RNA::energy_set, + "P=s" => \$ParamFile, + "nsp=s" => \$ns_bases, + "S=f" => \$sfact); + + RNA::read_parameter_file($ParamFile) if ($ParamFile); + +if ($ns_bases) { + $RNA::nonstandards = ""; + foreach my $p ( split(/,/, $ns_bases) ) { + if ($p =~ s/^-//) { + $RNA::nonstandards .= reverse($p) + } + $RNA::nonstandards .= $p; + } + print "$RNA::nonstandards\n"; +} + +my $istty = (-t STDIN) && (-t STDOUT); +if (($RNA::fold_constrained)&&($istty)) { +print < : base i is paired with a base j>i +matching brackets ( ): base i pairs base j +END +} + +if ($istty) { + print "\nInput string (upper or lower case); @ to quit\n"; + for (1..8) { print "....,....$_";} + print "\n"; +} +my $fname; +while (<>) { # main loop: continue until end of file + my ($string, $cstruc, $structure, $min_en); + # skip comment lines and get filenames + if (/^>\s*(\S*)/) { + $fname = $1; + next; + } + last if (/^@/); + + if (/(\S+)/) { + $string = $1; + } else { + next; + } + + $string = uc($string); + my $length = length($string); + printf("length = %d\n", $length) if ($istty); + + if ($RNA::fold_constrained) { + $_ = <>; + $cstruc = $1 if (/(\S+)/); + die("constraint string has wrong length") + if (length($cstruc)!=$length); + ($structure, $min_en) = RNA::fold($string, $structure); + } else { + ($structure, $min_en) = RNA::fold($string); + } + print "$string\n$structure"; + if ($istty) { + printf("\n minimum free energy = %6.2f kcal/mol\n", $min_en); + } else { + printf(" (%6.2f)\n", $min_en); + } + my $ffname = ($fname) ? ($fname . '_ss.ps') : 'rna.ps'; + RNA::PS_rna_plot($string, $structure, $ffname); + + if ($pf) { + + # recompute with dangles as in pf_fold() + $RNA::dangles=2 if ($RNA::dangles); + $min_en = RNA::energy_of_struct($string, $structure); + + my $kT = ($RNA::temperature+273.15)*1.98717/1000.; # in Kcal + $RNA::pf_scale = exp(-($sfact*$min_en)/$kT/$length); + print STDERR "scaling factor $RNA::pf_scale\n" if ($length>2000); + + $structure = $cstruc if ($RNA::fold_constrained); + my $energy = RNA::pf_fold($string, $structure); + + if ($RNA::do_backtrack) { + print $structure; + printf(" [%6.2f]\n", $energy) if (!$istty); + print "\n"; + } + if (($istty)||(!$RNA::do_backtrack)) { + printf(" free energy of ensemble = %6.2f kcal/mol\n", $energy); + printf(" frequency of mfe structure in ensemble %g\n", + exp(($energy-$min_en)/$kT)); + } + + if ($RNA::do_backtrack) { + $ffname = ($fname)?($fname . "_dp.ps"):"dot.ps"; + &RNA::PS_dot_plot($string, $ffname); + } + } + undef $fname; +} + + RNA::free_pf_arrays() if ($pf); + RNA::free_arrays(); + +sub usage() +{ + die("usage: " . + "RNAfold [-p[0]] [-C] [-T temp] [-4] [-d] [-noGU] [-noCloseGU]\n" . + " [-e e_set] [-P paramfile] [-nsp pairs] [-S scale]"); +} + + +# End of file diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/.exists b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/.exists new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/RNA.bs b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/RNA.bs new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/RNA.so b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/arch/auto/RNA/RNA.so new 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zY0^#%G_sxIUW0GcXYnD6;_d0IbwJ1ArG0oWu^CBQGJya-cM=f z00yH|vU`35CZOb&C3Z|Eu6Oe^0Q2U}4t3e6mrndT>|snYOO0;Arl+n*-?zauF&G5sdrXLGxBBi$ZyILKl5?U6>-ANC!d1GpFI zlXbCJsYXb>IpaPKK_PC`{b1@qhb_db%6@Iqlm^9jt)Ly)-9o^li-y5|aL1jiH<0M4 z_oiFbKA)C2^CqihKSGW`SAiqJ*BaEMtNF>q1cu{lBIe>|PY=MQ-FZS>#LRuY+ee;Z zbEUuzK2kYGg|J|l$4o5*e`9XLTcrOp;LzDe e_7IN==t#6nHCt*j(==1 the CONSTRAINTS string is +used to specify constraints on the predicted structure. The +characters '|', 'x', '<', '>' mark bases that are paired, unpaired, +paired upstream, or downstream, respectively; matching brackets "( )" +denote base pairs, dots '.' are used for unconstrained bases. + +In the two argument version the CONSTRAINTS string is modified and holds the +predicted structure upon return. This is done for backwards compatibility only, +and might change in future versions. + +=item energy_of_struct SEQUENCE, STRUCTURE + +returns the energy of SEQUENCE on STRUCTURE (in kcal/mol). The string structure +must hold a valid secondary structure in bracket notation. + +=item update_fold_params + +recalculate the pair matrix and energy parameters after a change in folding +parameters. In many cases (such as changes to +L<$temperature|/$temperature>) the fold() routine will call +update_fold_params automatically when necessary. + +=item free_arrays + +frees memory allocated internally when calling L. + +=back + +Partition function Folding (from part_func.h) + +=over 4 + +=item pf_fold SEQUENCE + +=item pf_fold SEQUENCE, CONSTRAINTS + +calculates the partition function over all possible secondary +structures and the matrix of pair probabilities for SEQUENCE and +returns a two element list consisting of a string summarizing possible +structures. See below on how to access the pair probability matrix. As +with L the second argument can be used to specify folding +constraints. Constraints are implemented by excluding base pairings +that contradict the constraint, but without bonus +energies. Constraints of type '|' (paired base) are ignored. In the +two argument version CONSTRAINTS is modified to contain the structure +string on return (obsolete feature, for backwards compatibility only) + +=item get_pr I, J + +After calling C the global C variable C points to the +computed pair probabilities. Perl access to the C is facilitated by +the C helper function that looks up and returns the +probability of the pair (I,J). + +=item free_pf_arrays + +frees memory allocated for pf_fold + +=item update_pf_params LENGTH + +recalculate energy parameters for pf_fold. In most cases (such as +simple changes to L<$temperature|/$temperature>) C +will take appropriate action automatically. + +=back + +Suboptimal Folding (from subopt.h) + +=over 4 + +=item subopt SEQUENCE, CONSTRAINTS, DELTA + +=item subopt SEQUENCE, CONSTRAINTS, DELTA, FILEHANDLE + +compute all structures of SEQUENCE within DELTA*0.01 kcal/mol of the +optimum. If specified, results are written to FILEHANDLE and nothing +is returned. Else, the C function returnes a list of C structs of type +SOLUTION. The list is wrapped by SWIG as a perl object that can be +accesses as follows: + + $solution = subopt($seq, undef, 500); + for (0..$solution->size()-1) { + printf "%s %6.2f\n", $solution->get($_)->{structure}, + $solution->get($_)->{energy}; + } + +=back + +Inverse Folding (from inverse.h) + +=over 4 + +=item inverse_fold START, TARGET + +find a sequence that folds into structure TARGET, by optimizing the +sequence until its mfe structure (as returned by L) is +TARGET. Startpoint of the optimization is the sequence START. Returns +a list containing the sequence found and the final value of the cost +function, i.e. 0 if the search was successful. A random start sequence +can be generated using L. + +=item inverse_pf_fold START, TARGET + +optimizes a sequence (beginning with START) by maximising the +frequency of the structure TARGET in the thermodynamic ensemble +of structures. Returns a list containing the optimized sequence and +the final value of the cost function. The cost function is given by +C, i.e.C<-RT*log(p(TARGET))> + +=item $final_cost [float] + +holds the value of the cost function where the optimization in +C should stop. For values <=0 the optimization will +only terminate at a local optimimum (which might take very long to reach). + +=item $symbolset [char *] + +the string symbolset holds the allowed characters to be used by +C and C, the default alphabet is "AUGC" + + +=item $give_up [int] + +If non-zero stop optimization when its clear that no exact solution +can be found. Else continue and eventually return an approximate +solution. Default 0. + +=back + +Global Variables to Modify Folding (from fold_vars.h) + +=over 4 + +=item $noGU [int] + +Do not allow GU pairs to form, default 0. + +=item $no_closingGU [int] + +allow GU only inside stacks, default 0. + +=item $tetra_loop [int] + +Fold with specially stable 4-loops, default 1. + +=item $energy_set [int] + +0 = BP; 1=any mit GC; 2=any mit AU-parameter, default 0. + +=item $dangles [int] + +How to compute dangling ends. 0: no dangling end energies, 1: "normal" +dangling ends (default), 2: simplified dangling ends, 3: "normal" + +co-axial stacking. Note that L treats cases 1 and 3 +as 2. The same holds for the main computation in L, +however subopt will re-evalute energies using +L for cases 1 and 3. See the more +detailed discussion in RNAlib.texinfo. + +=item $nonstandards [char *] + +contains allowed non standard bases, default empty string "" + +=item $temperature [double] + +temperature in degrees Celsius for rescaling parameters, default 37C. + +=item $logML [int] + +use logarithmic multiloop energy function in +L, default 0. + +=item $noLonelyPairs [int] + +consider only structures without isolated base pairs (helices of length 1). +For L only eliminates pairs +that can B occur as isolated pairs. Default 0. + +=item $base_pair [struct bond *] + +list of base pairs from last call to L. Better use +the structure string returned by L. + +=item $pf_scale [double] + +scaling factor used by L to avoid overflows. Should +be set to exp(-F/(RT*length)) where F is a guess for the ensmble free +energy (e.g. use the mfe). + + +=item $fold_constrained [int] + +apply constraints in the folding algorithms, default 0. + +=item $do_backtrack [int] + +If 0 do not compute the pair probabilities in L +(only the partition function). Default 1. + +=item $backtrack_type [char] + +usually 'F'; 'C' require (1,N) to be bonded; 'M' backtrack as if the +sequence was part of a multi loop. Used by L + +=item $pr [double *] + +the base pairing prob. matrix computed by L. + +=item $iindx [int *] + +Array of indices for moving withing the C array. Better use +L. + + +=back + +=head2 Parsing and Comparing Structures + +from RNAstruct.h: these functions convert between strings +representating secondary structures with various levels of coarse +graining. See the documentation of the C library for details + +=over 4 + +=item b2HIT STRUCTURE + +Full -> HIT [incl. root] + +=item b2C STRUCTURE + +Full -> Coarse [incl. root] + +=item b2Shapiro STRUCTURE + +Full -> weighted Shapiro [i.r.] + +=item add_root STRUCTURE + +{Tree} -> ({Tree}R) + +=item expand_Shapiro COARSE + +add S for stacks to coarse struct + +=item expand_Full STRUCTURE + +Full -> FFull + +=item unexpand_Full FSTRUCTURE + +FFull -> Full + +=item unweight WCOARSE + +remove weights from coarse struct + +=item unexpand_aligned_F ALIGN + + + +=item parse_structure STRUCTURE + +computes structure statistics, and fills the following global variables: + +$loops [int] number of loops (and stacks) +$unpaired [int] number of unpaired positions +$pairs [int] number of paired positions +$loop_size[int *] holds all loop sizes +$loop_degree[int *] holds all loop degrees +$helix_size[int *] holds all helix lengths + +=back + +from treedist.h: routines for computing tree-edit distances between structures + +=over 4 + +=item make_tree STRUCTURE + +make input for tree_edit_distance (a Tree * pointer). + +=item tree_edit_distance T1, T2 + +compare to structures using tree editing. C, C must have been +created using C + +=item print_tree T + +mainly for debugging + +=item free_tree T + +free space allocated by make_tree + +=back + +from stringdist.h routines to compute structure distances via string-editing + +=over 4 + +=item Make_swString STRUCTURE + +[ returns swString * ] +make input for string_edit_distance + +=item string_edit_distance S1, S2 + +[ returns float ] +compare to structures using string alignment. C, C should be +created using C + +=back + +from profiledist + +=over + +=item Make_bp_profile LENGTH + +[ returns (float *) ] +condense pair probability matrix C into a vector containing +probabilities for upstream paired, downstream paired and +unpaired. This resulting probability profile is used as input for +profile_edit_distance + +=item profile_edit_distance T1, T2 + +[ returns float ] +align two probability profiles produced by C + +=item print_bppm T + +[ returns void ] +print string representation of probability profile + +=item free_profile T + +[ returns void ] +free space allocated in Make_bp_profile + +=back + +Global variables for computing structure distances + +=over 4 + +=item $edit_backtrack [int] + +set to 1 if you want backtracking + +=item $aligned_line [(char *)[2]] + +containes alignmed structures after computing structure distance with +C + +=item $cost_matrix [int] + +0 usual costs (default), 1 Shapiro's costs + +=back + +=head2 Utilities (from utils.h) + +=over 4 + +=item space SIZE + +allocate memory from C. Usually not needed in Perl + +=item nrerror MESSGAE + +die with error message. Better use Perl's C + +=item $xsubi [unsigned short[3]] + +libRNA uses the rand48 48bit random number generator if available, the +current random number is always stored in $xsubi. + +=item init_rand + +initialize the $xsubi random number from current time + +=item urn + +returns a random number between 0 and 1 using the random number +generator from the RNA library. + +=item int_urn FROM, TO + +returns random integer in the range [FROM..TO] + +=item time_stamp + +current date in a string. In perl you might as well use C + +=item random_string LENGTH, SYMBOLS + +returns a string of length LENGTH using characters from the string +SYMBOLS + +=item hamming S1, S2 + +calculate hamming distance of the strings C and C. + + +=item pack_structure STRUCTURE + +pack secondary structure, using a 5:1 compression via 3 +encoding. Returns the packed string. + +=item unpack_structure PACKED + +unpacks a secondary structure packed with pack_structure + +=item make_pair_table STRUCTURE + +returns a pair table as a newly allocated (short *) C array, such +that: table[i]=j if (i.j) pair or 0 if i is unpaired, table[0] +contains the length of the structure. + +=item bp_distance STRUCTURE1, STRUCTURE2 + +returns the base pair distance of the two STRUCTURES. dist = {number +of base pairs in one structure but not in the other} same as edit +distance with open-pair close-pair as move-set + +=back + +from PS_plot.h + +=over 4 + +=item PS_rna_plot SEQUENCE, STRUCTURE, FILENAME + +write PostScript drawing of structure to FILENAME. Returns 1 on +sucess, 0 else. + +=item PS_rna_plot_a SEQUENCE, STRUCTURE, FILENAME, PRE, POST + +write PostScript drawing of structure to FILENAME. The strings PRE and +POST contain PostScript code that is included verbatim in the plot just +before (after) the data. Returns 1 on sucess, 0 else. + +=item gmlRNA SEQUENCE, STRUCTURE, FILENAME, OPTION + +write structure drawing in gml (Graph Meta Language) to +FILENAME. OPTION should be a single character. If uppercase the gml +output will include the SEQUENCE as node labels. IF OPTION equal 'x' +or 'X' write graph with coordinates (else only connectivity +information). Returns 1 on sucess, 0 else. + +=item ssv_rna_plot SEQUENCE, STRUCTURE, SSFILE + +write structure drfawing as coord file for SStructView Returns 1 on +sucess, 0 else. + +=item xrna_plot SEQUENCE, STRUCTURE, SSFILE + +write structure drawing as ".ss" file for further editing in XRNA. +Returns 1 on sucess, 0 else. + +=item PS_dot_plot SEQUENCE, FILENAME + +write a PostScript dot plot of the pair probability matix to +FILENAME. Returns 1 on sucess, 0 else. + +=item $rna_plot_type [int] + +Select layout algorithm for structure drawings. Currently available +0= simple coordinates, 1= naview, default 1. + +=back + +from read_epars.c + +=over 4 + +=item read_parameter_file FILENAME + +read energy parameters from FILENAME + +=item write_parameter_file FILENAME + +write energy parameters to FILENAME + +=back + +=head2 SWIG helper functions + +The package includes generic helper functions to access C arrays +of type C, C and C, such as: + +=over 4 + +=item intP_getitem POINTER, INDEX + +return the element INDEX from the array + +=item intP_setitem POINTER, INDEX, VALUE + +set element INDEX to VALUE + +=item new_intP NELEM + +allocate a new C array of integers with NELEM elements and return the pointer + +=item delete_intP POINTER + +deletes the C array by calling free() + +=back + +substituting C with C or C gives the corresponding +functions for arrays of float or double. You need to know the correct C +type however, and the function work only for arrays of simple types. + +On the lowest level the C function gives direct access to any data +in the form of a Perl string. + +=over + +=item cdata POINTER, SIZE + +copies SIZE bytes at POINTER to a Perl string (with binary data) + +=item memmove POINTER, STRING + +copies the (binary) string STRING to the memory location pointed to by +POINTER. + + +=back + +In combination with Perl's C this provides a generic way to convert +C data structures to Perl. E.g. + + RNA::parse_structure($structure); # fills the $RNA::loop_degree array + @ldegrees = unpack "I*", RNA::cdata($RNA::loop_degree, ($RNA::loops+1)*4); + +Warning: using these functions with wrong arguments will corrupt your +memory and lead to a segmentation fault. + +=head1 AUTHOR + +Ivo L. Hofacker + +=cut + +# ---------- BASE METHODS ------------- + +package RNA; + +sub TIEHASH { + my ($classname,$obj) = @_; + return bless $obj, $classname; +} + +sub CLEAR { } + +sub FIRSTKEY { } + +sub NEXTKEY { } + +sub FETCH { + my ($self,$field) = @_; + my $member_func = "swig_${field}_get"; + $self->$member_func(); +} + +sub STORE { + my ($self,$field,$newval) = @_; + my $member_func = "swig_${field}_set"; + $self->$member_func($newval); +} + +sub this { + my $ptr = shift; + return tied(%$ptr); +} + + +# ------- FUNCTION WRAPPERS -------- + +package RNA; + +*new_intP = *RNAc::new_intP; +*delete_intP = *RNAc::delete_intP; +*intP_getitem = *RNAc::intP_getitem; +*intP_setitem = *RNAc::intP_setitem; +*new_floatP = *RNAc::new_floatP; +*delete_floatP = *RNAc::delete_floatP; +*floatP_getitem = *RNAc::floatP_getitem; +*floatP_setitem = *RNAc::floatP_setitem; +*new_doubleP = *RNAc::new_doubleP; +*delete_doubleP = *RNAc::delete_doubleP; +*doubleP_getitem = *RNAc::doubleP_getitem; +*doubleP_setitem = *RNAc::doubleP_setitem; +*new_shortP = *RNAc::new_shortP; +*delete_shortP = *RNAc::delete_shortP; +*shortP_getitem = *RNAc::shortP_getitem; +*shortP_setitem = *RNAc::shortP_setitem; +*cdata = *RNAc::cdata; +*memmove = *RNAc::memmove; +*fold = *RNAc::fold; +*energy_of_struct = *RNAc::energy_of_struct; +*free_arrays = *RNAc::free_arrays; +*initialize_fold = *RNAc::initialize_fold; +*update_fold_params = *RNAc::update_fold_params; +*cofold = *RNAc::cofold; +*free_co_arrays = *RNAc::free_co_arrays; +*initialize_cofold = *RNAc::initialize_cofold; +*update_cofold_params = *RNAc::update_cofold_params; +*pf_fold = *RNAc::pf_fold; +*init_pf_fold = *RNAc::init_pf_fold; +*free_pf_arrays = *RNAc::free_pf_arrays; +*update_pf_params = *RNAc::update_pf_params; +*bppm_symbol = *RNAc::bppm_symbol; +*mean_bp_dist = *RNAc::mean_bp_dist; +*pbacktrack = *RNAc::pbacktrack; +*inverse_fold = *RNAc::inverse_fold; +*inverse_pf_fold = *RNAc::inverse_pf_fold; +*option_string = *RNAc::option_string; +*subopt = *RNAc::subopt; +*get_pr = *RNAc::get_pr; +*b2HIT = *RNAc::b2HIT; +*b2C = *RNAc::b2C; +*b2Shapiro = *RNAc::b2Shapiro; +*add_root = *RNAc::add_root; +*expand_Shapiro = *RNAc::expand_Shapiro; +*expand_Full = *RNAc::expand_Full; +*unexpand_Full = *RNAc::unexpand_Full; +*unweight = *RNAc::unweight; +*unexpand_aligned_F = *RNAc::unexpand_aligned_F; +*parse_structure = *RNAc::parse_structure; +*make_tree = *RNAc::make_tree; +*tree_edit_distance = *RNAc::tree_edit_distance; +*print_tree = *RNAc::print_tree; +*free_tree = *RNAc::free_tree; +*Make_swString = *RNAc::Make_swString; +*string_edit_distance = *RNAc::string_edit_distance; +*Make_bp_profile = *RNAc::Make_bp_profile; +*profile_edit_distance = *RNAc::profile_edit_distance; +*print_bppm = *RNAc::print_bppm; +*free_profile = *RNAc::free_profile; +*space = *RNAc::space; +*xrealloc = *RNAc::xrealloc; +*nrerror = *RNAc::nrerror; +*init_rand = *RNAc::init_rand; +*urn = *RNAc::urn; +*int_urn = *RNAc::int_urn; +*filecopy = *RNAc::filecopy; +*time_stamp = *RNAc::time_stamp; +*random_string = *RNAc::random_string; +*hamming = *RNAc::hamming; +*get_line = *RNAc::get_line; +*pack_structure = *RNAc::pack_structure; +*unpack_structure = *RNAc::unpack_structure; +*make_pair_table = *RNAc::make_pair_table; +*bp_distance = *RNAc::bp_distance; +*read_parameter_file = *RNAc::read_parameter_file; +*write_parameter_file = *RNAc::write_parameter_file; +*deref_any = *RNAc::deref_any; +*scale_parameters = *RNAc::scale_parameters; +*copy_parameters = *RNAc::copy_parameters; +*set_parameters = *RNAc::set_parameters; +*get_aligned_line = *RNAc::get_aligned_line; +*make_loop_index = *RNAc::make_loop_index; +*energy_of_move = *RNAc::energy_of_move; +*PS_rna_plot = *RNAc::PS_rna_plot; +*PS_rna_plot_a = *RNAc::PS_rna_plot_a; +*gmlRNA = *RNAc::gmlRNA; +*ssv_rna_plot = *RNAc::ssv_rna_plot; +*svg_rna_plot = *RNAc::svg_rna_plot; +*xrna_plot = *RNAc::xrna_plot; +*PS_dot_plot = *RNAc::PS_dot_plot; +*PS_color_dot_plot = *RNAc::PS_color_dot_plot; +*PS_dot_plot_list = *RNAc::PS_dot_plot_list; + +############# Class : RNA::intArray ############## + +package RNA::intArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_intArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_intArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::intArray_getitem; +*setitem = *RNAc::intArray_setitem; +*cast = *RNAc::intArray_cast; +*frompointer = *RNAc::intArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::floatArray ############## + +package RNA::floatArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_floatArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_floatArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::floatArray_getitem; +*setitem = *RNAc::floatArray_setitem; +*cast = *RNAc::floatArray_cast; +*frompointer = *RNAc::floatArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::doubleArray ############## + +package RNA::doubleArray; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +sub new { + my $pkg = shift; + my $self = RNAc::new_doubleArray(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_doubleArray($self); + delete $OWNER{$self}; + } +} + +*getitem = *RNAc::doubleArray_getitem; +*setitem = *RNAc::doubleArray_setitem; +*cast = *RNAc::doubleArray_cast; +*frompointer = *RNAc::doubleArray_frompointer; +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::bondT ############## + +package RNA::bondT; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::bondT_i_get; +*swig_i_set = *RNAc::bondT_i_set; +*swig_j_get = *RNAc::bondT_j_get; +*swig_j_set = *RNAc::bondT_j_set; +*get = *RNAc::bondT_get; +sub new { + my $pkg = shift; + my $self = RNAc::new_bondT(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_bondT($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::SOLUTION ############## + +package RNA::SOLUTION; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_energy_get = *RNAc::SOLUTION_energy_get; +*swig_energy_set = *RNAc::SOLUTION_energy_set; +*swig_structure_get = *RNAc::SOLUTION_structure_get; +*swig_structure_set = *RNAc::SOLUTION_structure_set; +*get = *RNAc::SOLUTION_get; +*size = *RNAc::SOLUTION_size; +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_SOLUTION($self); + delete $OWNER{$self}; + } +} + +sub new { + my $pkg = shift; + my $self = RNAc::new_SOLUTION(@_); + bless $self, $pkg if defined($self); +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::cpair ############## + +package RNA::cpair; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::cpair_i_get; +*swig_i_set = *RNAc::cpair_i_set; +*swig_j_get = *RNAc::cpair_j_get; +*swig_j_set = *RNAc::cpair_j_set; +*swig_mfe_get = *RNAc::cpair_mfe_get; +*swig_mfe_set = *RNAc::cpair_mfe_set; +*swig_p_get = *RNAc::cpair_p_get; +*swig_p_set = *RNAc::cpair_p_set; +*swig_hue_get = *RNAc::cpair_hue_get; +*swig_hue_set = *RNAc::cpair_hue_set; +*swig_sat_get = *RNAc::cpair_sat_get; +*swig_sat_set = *RNAc::cpair_sat_set; +sub new { + my $pkg = shift; + my $self = RNAc::new_cpair(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_cpair($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +############# Class : RNA::plist ############## + +package RNA::plist; +@ISA = qw( RNA ); +%OWNER = (); +%ITERATORS = (); +*swig_i_get = *RNAc::plist_i_get; +*swig_i_set = *RNAc::plist_i_set; +*swig_j_get = *RNAc::plist_j_get; +*swig_j_set = *RNAc::plist_j_set; +*swig_p_get = *RNAc::plist_p_get; +*swig_p_set = *RNAc::plist_p_set; +sub new { + my $pkg = shift; + my $self = RNAc::new_plist(@_); + bless $self, $pkg if defined($self); +} + +sub DESTROY { + return unless $_[0]->isa('HASH'); + my $self = tied(%{$_[0]}); + return unless defined $self; + delete $ITERATORS{$self}; + if (exists $OWNER{$self}) { + RNAc::delete_plist($self); + delete $OWNER{$self}; + } +} + +sub DISOWN { + my $self = shift; + my $ptr = tied(%$self); + delete $OWNER{$ptr}; +} + +sub ACQUIRE { + my $self = shift; + my $ptr = tied(%$self); + $OWNER{$ptr} = 1; +} + + +# ------- VARIABLE STUBS -------- + +package RNA; + +*VERSION = *RNAc::VERSION; +*symbolset = *RNAc::symbolset; +*final_cost = *RNAc::final_cost; +*give_up = *RNAc::give_up; +*noGU = *RNAc::noGU; +*no_closingGU = *RNAc::no_closingGU; +*tetra_loop = *RNAc::tetra_loop; +*energy_set = *RNAc::energy_set; +*dangles = *RNAc::dangles; +*nonstandards = *RNAc::nonstandards; +*temperature = *RNAc::temperature; +*james_rule = *RNAc::james_rule; +*logML = *RNAc::logML; +*cut_point = *RNAc::cut_point; + +my %__base_pair_hash; +tie %__base_pair_hash,"RNA::bondT", $RNAc::base_pair; +$base_pair= \%__base_pair_hash; +bless $base_pair, RNA::bondT; +*pr = *RNAc::pr; +*iindx = *RNAc::iindx; +*pf_scale = *RNAc::pf_scale; +*fold_constrained = *RNAc::fold_constrained; +*do_backtrack = *RNAc::do_backtrack; +*noLonelyPairs = *RNAc::noLonelyPairs; +*backtrack_type = *RNAc::backtrack_type; +*subopt_sorted = *RNAc::subopt_sorted; +*loop_size = *RNAc::loop_size; +*helix_size = *RNAc::helix_size; +*loop_degree = *RNAc::loop_degree; +*loops = *RNAc::loops; +*unpaired = *RNAc::unpaired; +*pairs = *RNAc::pairs; +*edit_backtrack = *RNAc::edit_backtrack; +*aligned_line = *RNAc::aligned_line; +*cost_matrix = *RNAc::cost_matrix; +*xsubi = *RNAc::xsubi; +*rna_plot_type = *RNAc::rna_plot_type; +1; diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/lib/auto/RNA/.exists b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/lib/auto/RNA/.exists new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/man3/.exists b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/man3/.exists new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/man3/RNA.3pm b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/man3/RNA.3pm new file mode 100755 index 00000000..063e052a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/blib/man3/RNA.3pm @@ -0,0 +1,588 @@ +.\" Automatically generated by Pod::Man v1.34, Pod::Parser v1.13 +.\" +.\" Standard preamble: +.\" ======================================================================== +.de Sh \" Subsection heading +.br +.if t .Sp +.ne 5 +.PP +\fB\\$1\fR +.PP +.. +.de Sp \" Vertical space (when we can't use .PP) +.if t .sp .5v +.if n .sp +.. +.de Vb \" Begin verbatim text +.ft CW +.nf +.ne \\$1 +.. +.de Ve \" End verbatim text +.ft R +.fi +.. +.\" Set up some character translations and predefined strings. \*(-- will +.\" give an unbreakable dash, \*(PI will give pi, \*(L" will give a left +.\" double quote, and \*(R" will give a right double quote. | will give a +.\" real vertical bar. \*(C+ will give a nicer C++. Capital omega is used to +.\" do unbreakable dashes and therefore won't be available. \*(C` and \*(C' +.\" expand to `' in nroff, nothing in troff, for use with C<>. +.tr \(*W-|\(bv\*(Tr +.ds C+ C\v'-.1v'\h'-1p'\s-2+\h'-1p'+\s0\v'.1v'\h'-1p' +.ie n \{\ +. ds -- \(*W- +. ds PI pi +. if (\n(.H=4u)&(1m=24u) .ds -- \(*W\h'-12u'\(*W\h'-12u'-\" diablo 10 pitch +. if (\n(.H=4u)&(1m=20u) .ds -- \(*W\h'-12u'\(*W\h'-8u'-\" diablo 12 pitch +. ds L" "" +. ds R" "" +. ds C` "" +. ds C' "" +'br\} +.el\{\ +. ds -- \|\(em\| +. ds PI \(*p +. ds L" `` +. ds R" '' +'br\} +.\" +.\" If the F register is turned on, we'll generate index entries on stderr for +.\" titles (.TH), headers (.SH), subsections (.Sh), items (.Ip), and index +.\" entries marked with X<> in POD. Of course, you'll have to process the +.\" output yourself in some meaningful fashion. +.if \nF \{\ +. de IX +. tm Index:\\$1\t\\n%\t"\\$2" +.. +. nr % 0 +. rr F +.\} +.\" +.\" For nroff, turn off justification. Always turn off hyphenation; it makes +.\" way too many mistakes in technical documents. +.hy 0 +.if n .na +.\" +.\" Accent mark definitions (@(#)ms.acc 1.5 88/02/08 SMI; from UCB 4.2). +.\" Fear. Run. Save yourself. No user-serviceable parts. +. \" fudge factors for nroff and troff +.if n \{\ +. ds #H 0 +. ds #V .8m +. ds #F .3m +. ds #[ \f1 +. ds #] \fP +.\} +.if t \{\ +. ds #H ((1u-(\\\\n(.fu%2u))*.13m) +. ds #V .6m +. ds #F 0 +. ds #[ \& +. ds #] \& +.\} +. \" simple accents for nroff and troff +.if n \{\ +. ds ' \& +. ds ` \& +. ds ^ \& +. ds , \& +. ds ~ ~ +. ds / +.\} +.if t \{\ +. ds ' \\k:\h'-(\\n(.wu*8/10-\*(#H)'\'\h"|\\n:u" +. ds ` \\k:\h'-(\\n(.wu*8/10-\*(#H)'\`\h'|\\n:u' +. ds ^ \\k:\h'-(\\n(.wu*10/11-\*(#H)'^\h'|\\n:u' +. ds , \\k:\h'-(\\n(.wu*8/10)',\h'|\\n:u' +. ds ~ \\k:\h'-(\\n(.wu-\*(#H-.1m)'~\h'|\\n:u' +. ds / \\k:\h'-(\\n(.wu*8/10-\*(#H)'\z\(sl\h'|\\n:u' +.\} +. \" troff and (daisy-wheel) nroff accents +.ds : \\k:\h'-(\\n(.wu*8/10-\*(#H+.1m+\*(#F)'\v'-\*(#V'\z.\h'.2m+\*(#F'.\h'|\\n:u'\v'\*(#V' +.ds 8 \h'\*(#H'\(*b\h'-\*(#H' +.ds o \\k:\h'-(\\n(.wu+\w'\(de'u-\*(#H)/2u'\v'-.3n'\*(#[\z\(de\v'.3n'\h'|\\n:u'\*(#] +.ds d- \h'\*(#H'\(pd\h'-\w'~'u'\v'-.25m'\f2\(hy\fP\v'.25m'\h'-\*(#H' +.ds D- D\\k:\h'-\w'D'u'\v'-.11m'\z\(hy\v'.11m'\h'|\\n:u' +.ds th \*(#[\v'.3m'\s+1I\s-1\v'-.3m'\h'-(\w'I'u*2/3)'\s-1o\s+1\*(#] +.ds Th \*(#[\s+2I\s-2\h'-\w'I'u*3/5'\v'-.3m'o\v'.3m'\*(#] +.ds ae a\h'-(\w'a'u*4/10)'e +.ds Ae A\h'-(\w'A'u*4/10)'E +. \" corrections for vroff +.if v .ds ~ \\k:\h'-(\\n(.wu*9/10-\*(#H)'\s-2\u~\d\s+2\h'|\\n:u' +.if v .ds ^ \\k:\h'-(\\n(.wu*10/11-\*(#H)'\v'-.4m'^\v'.4m'\h'|\\n:u' +. \" for low resolution devices (crt and lpr) +.if \n(.H>23 .if \n(.V>19 \ +\{\ +. ds : e +. ds 8 ss +. ds o a +. ds d- d\h'-1'\(ga +. ds D- D\h'-1'\(hy +. ds th \o'bp' +. ds Th \o'LP' +. ds ae ae +. ds Ae AE +.\} +.rm #[ #] #H #V #F C +.\" ======================================================================== +.\" +.IX Title "RNA 3" +.TH RNA 3 "2005-11-21" "perl v5.8.0" "User Contributed Perl Documentation" +.SH "SYNOPSIS" +.IX Header "SYNOPSIS" +.Vb 7 +\& use RNA; +\& $seq = "CGCAGGGAUACCCGCG"; +\& ($struct, $mfe) = RNA::fold($seq); #predict mfe structure of $seq +\& RNA::PS_rna_plot($seq, $struct, "rna.ps"); # write PS plot to rna.ps +\& $F = RNA::pf_fold($seq); # compute partition function and pair pobabilities +\& RNA::PS_dot_plot($seq, "dot.ps"); # write dot plot to dot.ps +\& ... +.Ve +.SH "DESCRIPTION" +.IX Header "DESCRIPTION" +The \s-1RNA\s0.pm package gives access to almost all functions in the libRNA.a +library of the Vienna \s-1RNA\s0 \s-1PACKAGE\s0. The Perl wrapper is generated using +\&\s-1SWIG\s0 http://www.swig.org/ with relatively little manual intervention. +For each C function in the library the perl package provides a function +of the same name and calling convention (with few exceptions). For +detailed information you should therefore also consult the documentation +of the library (info RNAlib). +.PP +Note that in general C arrays are wrapped into opaque objects that can +only be accessed via helper functions. \s-1SWIG\s0 provides a couple of general +purpose helper functions, see the section at the end of this file. C +structures are wrapped into Perl objects using \s-1SWIG\s0's shadow class +mechanism, resulting in a tied hash with keys named after the structure +members. +.PP +For the interrested reader we list for each scalar type of the +corepsonding C variable in brackets, and point out the header files +containing the C declaration. +.Sh "Folding Routines" +.IX Subsection "Folding Routines" +Minimum free Energy Folding (from fold.h) +.IP "fold \s-1SEQUENCE\s0" 4 +.IX Item "fold SEQUENCE" +.PD 0 +.IP "fold \s-1SEQUENCE\s0, \s-1CONSTRAINTS\s0" 4 +.IX Item "fold SEQUENCE, CONSTRAINTS" +.PD +computes the minimum free energy structure of the string \s-1SEQUENCE\s0 and returns +the predicted structure and energy, e.g. +.Sp +.Vb 1 +\& ($structure, $mfe) = RNA::fold("UGUGUCGAUGUGCUAU"); +.Ve +.Sp +If a second argument is supplied and +$fold_constrained==1 the \s-1CONSTRAINTS\s0 string is +used to specify constraints on the predicted structure. The +characters '|', 'x', '<', '>' mark bases that are paired, unpaired, +paired upstream, or downstream, respectively; matching brackets \*(L"( )\*(R" +denote base pairs, dots '.' are used for unconstrained bases. +.Sp +In the two argument version the \s-1CONSTRAINTS\s0 string is modified and holds the +predicted structure upon return. This is done for backwards compatibility only, +and might change in future versions. +.IP "energy_of_struct \s-1SEQUENCE\s0, \s-1STRUCTURE\s0" 4 +.IX Item "energy_of_struct SEQUENCE, STRUCTURE" +returns the energy of \s-1SEQUENCE\s0 on \s-1STRUCTURE\s0 (in kcal/mol). The string structure +must hold a valid secondary structure in bracket notation. +.IP "update_fold_params" 4 +.IX Item "update_fold_params" +recalculate the pair matrix and energy parameters after a change in folding +parameters. In many cases (such as changes to +$temperature) the \fIfold()\fR routine will call +update_fold_params automatically when necessary. +.IP "free_arrays" 4 +.IX Item "free_arrays" +frees memory allocated internally when calling fold. +.PP +Partition function Folding (from part_func.h) +.IP "pf_fold \s-1SEQUENCE\s0" 4 +.IX Item "pf_fold SEQUENCE" +.PD 0 +.IP "pf_fold \s-1SEQUENCE\s0, \s-1CONSTRAINTS\s0" 4 +.IX Item "pf_fold SEQUENCE, CONSTRAINTS" +.PD +calculates the partition function over all possible secondary +structures and the matrix of pair probabilities for \s-1SEQUENCE\s0 and +returns a two element list consisting of a string summarizing possible +structures. See below on how to access the pair probability matrix. As +with fold the second argument can be used to specify folding +constraints. Constraints are implemented by excluding base pairings +that contradict the constraint, but without bonus +energies. Constraints of type '|' (paired base) are ignored. In the +two argument version \s-1CONSTRAINTS\s0 is modified to contain the structure +string on return (obsolete feature, for backwards compatibility only) +.IP "get_pr I, J" 4 +.IX Item "get_pr I, J" +After calling \f(CW\*(C`pf_fold\*(C'\fR the global C variable \f(CW\*(C`pr\*(C'\fR points to the +computed pair probabilities. Perl access to the C is facilitated by +the \f(CW\*(C`get_pr\*(C'\fR helper function that looks up and returns the +probability of the pair (I,J). +.IP "free_pf_arrays" 4 +.IX Item "free_pf_arrays" +frees memory allocated for pf_fold +.IP "update_pf_params \s-1LENGTH\s0" 4 +.IX Item "update_pf_params LENGTH" +recalculate energy parameters for pf_fold. In most cases (such as +simple changes to $temperature) \f(CW\*(C`pf_fold\*(C'\fR +will take appropriate action automatically. +.PP +Suboptimal Folding (from subopt.h) +.IP "subopt \s-1SEQUENCE\s0, \s-1CONSTRAINTS\s0, \s-1DELTA\s0" 4 +.IX Item "subopt SEQUENCE, CONSTRAINTS, DELTA" +.PD 0 +.IP "subopt \s-1SEQUENCE\s0, \s-1CONSTRAINTS\s0, \s-1DELTA\s0, \s-1FILEHANDLE\s0" 4 +.IX Item "subopt SEQUENCE, CONSTRAINTS, DELTA, FILEHANDLE" +.PD +compute all structures of \s-1SEQUENCE\s0 within DELTA*0.01 kcal/mol of the +optimum. If specified, results are written to \s-1FILEHANDLE\s0 and nothing +is returned. Else, the C function returnes a list of C structs of type +\&\s-1SOLUTION\s0. The list is wrapped by \s-1SWIG\s0 as a perl object that can be +accesses as follows: +.Sp +.Vb 5 +\& $solution = subopt($seq, undef, 500); +\& for (0..$solution->size()-1) { +\& printf "%s %6.2f\en", $solution->get($_)->{structure}, +\& $solution->get($_)->{energy}; +\& } +.Ve +.PP +Inverse Folding (from inverse.h) +.IP "inverse_fold \s-1START\s0, \s-1TARGET\s0" 4 +.IX Item "inverse_fold START, TARGET" +find a sequence that folds into structure \s-1TARGET\s0, by optimizing the +sequence until its mfe structure (as returned by fold) is +\&\s-1TARGET\s0. Startpoint of the optimization is the sequence \s-1START\s0. Returns +a list containing the sequence found and the final value of the cost +function, i.e. 0 if the search was successful. A random start sequence +can be generated using random_string. +.IP "inverse_pf_fold \s-1START\s0, \s-1TARGET\s0" 4 +.IX Item "inverse_pf_fold START, TARGET" +optimizes a sequence (beginning with \s-1START\s0) by maximising the +frequency of the structure \s-1TARGET\s0 in the thermodynamic ensemble +of structures. Returns a list containing the optimized sequence and +the final value of the cost function. The cost function is given by +\&\f(CW\*(C`energy_of_struct(seq, TARGET) \- pf_fold(seq)\*(C'\fR, i.e.\f(CW\*(C`\-RT*log(p(TARGET))\*(C'\fR +.IP "$final_cost [float]" 4 +.IX Item "$final_cost [float]" +holds the value of the cost function where the optimization in +\&\f(CW\*(C`inverse_pf_fold\*(C'\fR should stop. For values <=0 the optimization will +only terminate at a local optimimum (which might take very long to reach). +.IP "$symbolset [char *]" 4 +.IX Item "$symbolset [char *]" +the string symbolset holds the allowed characters to be used by +\&\f(CW\*(C`inverse_fold\*(C'\fR and \f(CW\*(C`inverse_pf_fold\*(C'\fR, the default alphabet is \*(L"\s-1AUGC\s0\*(R" +.IP "$give_up [int]" 4 +.IX Item "$give_up [int]" +If non-zero stop optimization when its clear that no exact solution +can be found. Else continue and eventually return an approximate +solution. Default 0. +.PP +Global Variables to Modify Folding (from fold_vars.h) +.IP "$noGU [int]" 4 +.IX Item "$noGU [int]" +Do not allow \s-1GU\s0 pairs to form, default 0. +.IP "$no_closingGU [int]" 4 +.IX Item "$no_closingGU [int]" +allow \s-1GU\s0 only inside stacks, default 0. +.IP "$tetra_loop [int]" 4 +.IX Item "$tetra_loop [int]" +Fold with specially stable 4\-loops, default 1. +.IP "$energy_set [int]" 4 +.IX Item "$energy_set [int]" +0 = \s-1BP\s0; 1=any mit \s-1GC\s0; 2=any mit AU\-parameter, default 0. +.IP "$dangles [int]" 4 +.IX Item "$dangles [int]" +How to compute dangling ends. 0: no dangling end energies, 1: \*(L"normal\*(R" +dangling ends (default), 2: simplified dangling ends, 3: \*(L"normal\*(R" + +co-axial stacking. Note that pf_fold treats cases 1 and 3 +as 2. The same holds for the main computation in subopt, +however subopt will re-evalute energies using +energy_of_struct for cases 1 and 3. See the more +detailed discussion in RNAlib.texinfo. +.IP "$nonstandards [char *]" 4 +.IX Item "$nonstandards [char *]" +contains allowed non standard bases, default empty string "" +.IP "$temperature [double]" 4 +.IX Item "$temperature [double]" +temperature in degrees Celsius for rescaling parameters, default 37C. +.IP "$logML [int]" 4 +.IX Item "$logML [int]" +use logarithmic multiloop energy function in +energy_of_struct, default 0. +.IP "$noLonelyPairs [int]" 4 +.IX Item "$noLonelyPairs [int]" +consider only structures without isolated base pairs (helices of length 1). +For pf_fold only eliminates pairs +that can \fBonly\fR occur as isolated pairs. Default 0. +.IP "$base_pair [struct bond *]" 4 +.IX Item "$base_pair [struct bond *]" +list of base pairs from last call to fold. Better use +the structure string returned by fold. +.IP "$pf_scale [double]" 4 +.IX Item "$pf_scale [double]" +scaling factor used by pf_fold to avoid overflows. Should +be set to exp(\-F/(RT*length)) where F is a guess for the ensmble free +energy (e.g. use the mfe). +.IP "$fold_constrained [int]" 4 +.IX Item "$fold_constrained [int]" +apply constraints in the folding algorithms, default 0. +.IP "$do_backtrack [int]" 4 +.IX Item "$do_backtrack [int]" +If 0 do not compute the pair probabilities in pf_fold +(only the partition function). Default 1. +.IP "$backtrack_type [char]" 4 +.IX Item "$backtrack_type [char]" +usually 'F'; 'C' require (1,N) to be bonded; 'M' backtrack as if the +sequence was part of a multi loop. Used by inverse_fold +.IP "$pr [double *]" 4 +.IX Item "$pr [double *]" +the base pairing prob. matrix computed by pf_fold. +.IP "$iindx [int *]" 4 +.IX Item "$iindx [int *]" +Array of indices for moving withing the \f(CW\*(C`pr\*(C'\fR array. Better use +get_pr. +.Sh "Parsing and Comparing Structures" +.IX Subsection "Parsing and Comparing Structures" +from RNAstruct.h: these functions convert between strings +representating secondary structures with various levels of coarse +graining. See the documentation of the C library for details +.IP "b2HIT \s-1STRUCTURE\s0" 4 +.IX Item "b2HIT STRUCTURE" +Full \-> \s-1HIT\s0 [incl. root] +.IP "b2C \s-1STRUCTURE\s0" 4 +.IX Item "b2C STRUCTURE" +Full \-> Coarse [incl. root] +.IP "b2Shapiro \s-1STRUCTURE\s0" 4 +.IX Item "b2Shapiro STRUCTURE" +Full \-> weighted Shapiro [i.r.] +.IP "add_root \s-1STRUCTURE\s0" 4 +.IX Item "add_root STRUCTURE" +{Tree} \-> ({Tree}R) +.IP "expand_Shapiro \s-1COARSE\s0" 4 +.IX Item "expand_Shapiro COARSE" +add S for stacks to coarse struct +.IP "expand_Full \s-1STRUCTURE\s0" 4 +.IX Item "expand_Full STRUCTURE" +Full \-> FFull +.IP "unexpand_Full \s-1FSTRUCTURE\s0" 4 +.IX Item "unexpand_Full FSTRUCTURE" +FFull \-> Full +.IP "unweight \s-1WCOARSE\s0" 4 +.IX Item "unweight WCOARSE" +remove weights from coarse struct +.IP "unexpand_aligned_F \s-1ALIGN\s0" 4 +.IX Item "unexpand_aligned_F ALIGN" +.PD 0 +.IP "parse_structure \s-1STRUCTURE\s0" 4 +.IX Item "parse_structure STRUCTURE" +.PD +computes structure statistics, and fills the following global variables: +.Sp +$loops [int] number of loops (and stacks) +\&\f(CW$unpaired\fR [int] number of unpaired positions +\&\f(CW$pairs\fR [int] number of paired positions +\&\f(CW$loop_size\fR[int *] holds all loop sizes +\&\f(CW$loop_degree\fR[int *] holds all loop degrees +\&\f(CW$helix_size\fR[int *] holds all helix lengths +.PP +from treedist.h: routines for computing tree-edit distances between structures +.IP "make_tree \s-1STRUCTURE\s0" 4 +.IX Item "make_tree STRUCTURE" +make input for tree_edit_distance (a Tree * pointer). +.IP "tree_edit_distance T1, T2" 4 +.IX Item "tree_edit_distance T1, T2" +compare to structures using tree editing. \f(CW\*(C`T1\*(C'\fR, \f(CW\*(C`T2\*(C'\fR must have been +created using \f(CW\*(C`tree_edit_distance\*(C'\fR +.IP "print_tree T" 4 +.IX Item "print_tree T" +mainly for debugging +.IP "free_tree T" 4 +.IX Item "free_tree T" +free space allocated by make_tree +.PP +from stringdist.h routines to compute structure distances via string-editing +.IP "Make_swString \s-1STRUCTURE\s0" 4 +.IX Item "Make_swString STRUCTURE" +[ returns swString * ] +make input for string_edit_distance +.IP "string_edit_distance S1, S2" 4 +.IX Item "string_edit_distance S1, S2" +[ returns float ] +compare to structures using string alignment. \f(CW\*(C`S1\*(C'\fR, \f(CW\*(C`S2\*(C'\fR should be +created using \f(CW\*(C`Make_swString\*(C'\fR +.PP +from profiledist +.IP "Make_bp_profile \s-1LENGTH\s0" 4 +.IX Item "Make_bp_profile LENGTH" +[ returns (float *) ] +condense pair probability matrix \f(CW\*(C`pr\*(C'\fR into a vector containing +probabilities for upstream paired, downstream paired and +unpaired. This resulting probability profile is used as input for +profile_edit_distance +.IP "profile_edit_distance T1, T2" 4 +.IX Item "profile_edit_distance T1, T2" +[ returns float ] +align two probability profiles produced by \f(CW\*(C`Make_bp_profile\*(C'\fR +.IP "print_bppm T" 4 +.IX Item "print_bppm T" +[ returns void ] +print string representation of probability profile +.IP "free_profile T" 4 +.IX Item "free_profile T" +[ returns void ] +free space allocated in Make_bp_profile +.PP +Global variables for computing structure distances +.IP "$edit_backtrack [int]" 4 +.IX Item "$edit_backtrack [int]" +set to 1 if you want backtracking +.IP "$aligned_line [(char *)[2]]" 4 +.IX Item "$aligned_line [(char *)[2]]" +containes alignmed structures after computing structure distance with +\&\f(CW\*(C`edit_backtrack==1\*(C'\fR +.IP "$cost_matrix [int]" 4 +.IX Item "$cost_matrix [int]" +0 usual costs (default), 1 Shapiro's costs +.Sh "Utilities (from utils.h)" +.IX Subsection "Utilities (from utils.h)" +.IP "space \s-1SIZE\s0" 4 +.IX Item "space SIZE" +allocate memory from C. Usually not needed in Perl +.IP "nrerror \s-1MESSGAE\s0" 4 +.IX Item "nrerror MESSGAE" +die with error message. Better use Perl's \f(CW\*(C`die\*(C'\fR +.IP "$xsubi [unsigned short[3]]" 4 +.IX Item "$xsubi [unsigned short[3]]" +libRNA uses the rand48 48bit random number generator if available, the +current random number is always stored in \f(CW$xsubi\fR. +.IP "init_rand" 4 +.IX Item "init_rand" +initialize the \f(CW$xsubi\fR random number from current time +.IP "urn" 4 +.IX Item "urn" +returns a random number between 0 and 1 using the random number +generator from the \s-1RNA\s0 library. +.IP "int_urn \s-1FROM\s0, \s-1TO\s0" 4 +.IX Item "int_urn FROM, TO" +returns random integer in the range [\s-1FROM\s0..TO] +.IP "time_stamp" 4 +.IX Item "time_stamp" +current date in a string. In perl you might as well use \f(CW\*(C`locatime\*(C'\fR +.IP "random_string \s-1LENGTH\s0, \s-1SYMBOLS\s0" 4 +.IX Item "random_string LENGTH, SYMBOLS" +returns a string of length \s-1LENGTH\s0 using characters from the string +\&\s-1SYMBOLS\s0 +.IP "hamming S1, S2" 4 +.IX Item "hamming S1, S2" +calculate hamming distance of the strings \f(CW\*(C`S1\*(C'\fR and \f(CW\*(C`S2\*(C'\fR. +.IP "pack_structure \s-1STRUCTURE\s0" 4 +.IX Item "pack_structure STRUCTURE" +pack secondary structure, using a 5:1 compression via 3 +encoding. Returns the packed string. +.IP "unpack_structure \s-1PACKED\s0" 4 +.IX Item "unpack_structure PACKED" +unpacks a secondary structure packed with pack_structure +.IP "make_pair_table \s-1STRUCTURE\s0" 4 +.IX Item "make_pair_table STRUCTURE" +returns a pair table as a newly allocated (short *) C array, such +that: table[i]=j if (i.j) pair or 0 if i is unpaired, table[0] +contains the length of the structure. +.IP "bp_distance \s-1STRUCTURE1\s0, \s-1STRUCTURE2\s0" 4 +.IX Item "bp_distance STRUCTURE1, STRUCTURE2" +returns the base pair distance of the two \s-1STRUCTURES\s0. dist = {number +of base pairs in one structure but not in the other} same as edit +distance with open-pair close-pair as move-set +.PP +from PS_plot.h +.IP "PS_rna_plot \s-1SEQUENCE\s0, \s-1STRUCTURE\s0, \s-1FILENAME\s0" 4 +.IX Item "PS_rna_plot SEQUENCE, STRUCTURE, FILENAME" +write PostScript drawing of structure to \s-1FILENAME\s0. Returns 1 on +sucess, 0 else. +.IP "PS_rna_plot_a \s-1SEQUENCE\s0, \s-1STRUCTURE\s0, \s-1FILENAME\s0, \s-1PRE\s0, \s-1POST\s0" 4 +.IX Item "PS_rna_plot_a SEQUENCE, STRUCTURE, FILENAME, PRE, POST" +write PostScript drawing of structure to \s-1FILENAME\s0. The strings \s-1PRE\s0 and +\&\s-1POST\s0 contain PostScript code that is included verbatim in the plot just +before (after) the data. Returns 1 on sucess, 0 else. +.IP "gmlRNA \s-1SEQUENCE\s0, \s-1STRUCTURE\s0, \s-1FILENAME\s0, \s-1OPTION\s0" 4 +.IX Item "gmlRNA SEQUENCE, STRUCTURE, FILENAME, OPTION" +write structure drawing in gml (Graph Meta Language) to +\&\s-1FILENAME\s0. \s-1OPTION\s0 should be a single character. If uppercase the gml +output will include the \s-1SEQUENCE\s0 as node labels. \s-1IF\s0 \s-1OPTION\s0 equal 'x' +or 'X' write graph with coordinates (else only connectivity +information). Returns 1 on sucess, 0 else. +.IP "ssv_rna_plot \s-1SEQUENCE\s0, \s-1STRUCTURE\s0, \s-1SSFILE\s0" 4 +.IX Item "ssv_rna_plot SEQUENCE, STRUCTURE, SSFILE" +write structure drfawing as coord file for SStructView Returns 1 on +sucess, 0 else. +.IP "xrna_plot \s-1SEQUENCE\s0, \s-1STRUCTURE\s0, \s-1SSFILE\s0" 4 +.IX Item "xrna_plot SEQUENCE, STRUCTURE, SSFILE" +write structure drawing as \*(L".ss\*(R" file for further editing in \s-1XRNA\s0. +Returns 1 on sucess, 0 else. +.IP "PS_dot_plot \s-1SEQUENCE\s0, \s-1FILENAME\s0" 4 +.IX Item "PS_dot_plot SEQUENCE, FILENAME" +write a PostScript dot plot of the pair probability matix to +\&\s-1FILENAME\s0. Returns 1 on sucess, 0 else. +.IP "$rna_plot_type [int]" 4 +.IX Item "$rna_plot_type [int]" +Select layout algorithm for structure drawings. Currently available +0= simple coordinates, 1= naview, default 1. +.PP +from read_epars.c +.IP "read_parameter_file \s-1FILENAME\s0" 4 +.IX Item "read_parameter_file FILENAME" +read energy parameters from \s-1FILENAME\s0 +.IP "write_parameter_file \s-1FILENAME\s0" 4 +.IX Item "write_parameter_file FILENAME" +write energy parameters to \s-1FILENAME\s0 +.Sh "\s-1SWIG\s0 helper functions" +.IX Subsection "SWIG helper functions" +The package includes generic helper functions to access C arrays +of type \f(CW\*(C`int\*(C'\fR, \f(CW\*(C`float\*(C'\fR and \f(CW\*(C`double\*(C'\fR, such as: +.IP "intP_getitem \s-1POINTER\s0, \s-1INDEX\s0" 4 +.IX Item "intP_getitem POINTER, INDEX" +return the element \s-1INDEX\s0 from the array +.IP "intP_setitem \s-1POINTER\s0, \s-1INDEX\s0, \s-1VALUE\s0" 4 +.IX Item "intP_setitem POINTER, INDEX, VALUE" +set element \s-1INDEX\s0 to \s-1VALUE\s0 +.IP "new_intP \s-1NELEM\s0" 4 +.IX Item "new_intP NELEM" +allocate a new C array of integers with \s-1NELEM\s0 elements and return the pointer +.IP "delete_intP \s-1POINTER\s0" 4 +.IX Item "delete_intP POINTER" +deletes the C array by calling \fIfree()\fR +.PP +substituting \f(CW\*(C`intP\*(C'\fR with \f(CW\*(C`floatP\*(C'\fR or \f(CW\*(C`doubleP\*(C'\fR gives the corresponding +functions for arrays of float or double. You need to know the correct C +type however, and the function work only for arrays of simple types. +.PP +On the lowest level the \f(CW\*(C`cdata\*(C'\fR function gives direct access to any data +in the form of a Perl string. +.IP "cdata \s-1POINTER\s0, \s-1SIZE\s0" 4 +.IX Item "cdata POINTER, SIZE" +copies \s-1SIZE\s0 bytes at \s-1POINTER\s0 to a Perl string (with binary data) +.IP "memmove \s-1POINTER\s0, \s-1STRING\s0" 4 +.IX Item "memmove POINTER, STRING" +copies the (binary) string \s-1STRING\s0 to the memory location pointed to by +\&\s-1POINTER\s0. +.PP +In combination with Perl's \f(CW\*(C`unpack\*(C'\fR this provides a generic way to convert +C data structures to Perl. E.g. +.PP +.Vb 2 +\& RNA::parse_structure($structure); # fills the $RNA::loop_degree array +\& @ldegrees = unpack "I*", RNA::cdata($RNA::loop_degree, ($RNA::loops+1)*4); +.Ve +.PP +Warning: using these functions with wrong arguments will corrupt your +memory and lead to a segmentation fault. +.SH "AUTHOR" +.IX Header "AUTHOR" +Ivo L. Hofacker diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/pm_to_blib b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/pm_to_blib new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/test.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/test.pl new file mode 100755 index 00000000..0cd5b7d6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/test.pl @@ -0,0 +1,136 @@ +#!/usr/bin/perl -Iblib/arch -Iblib/lib + +# Last changed Time-stamp: <2005-07-23 16:04:56 ivo> + +######################### We start with some black magic to print on failure. +# (It may become useful if the test is moved to ./t subdirectory.) +use strict; +use Test; +use lib qw|blib/arch blib/lib|; + +BEGIN { plan tests => 19; } + +use RNA; +use warnings; + +######################### End of black magic. + +# Insert your test code below (better if it prints "ok 13" +# (correspondingly "not ok 13") depending on the success of chunk 13 +# of the test code): + +my $seq1 ="CGCAGGGAUACCCGCG"; +my $struc1="(((.((....)).)))"; +my $seq2 ="GCGCCCAUAGGGACGC"; +my $struc2="((((((...))).)))"; +# calculate a hamming distance (from util.c) +ok(RNA::hamming($seq1, $seq2), 16); + +# check a global variable +ok($RNA::temperature, 37); + +# fold a sequence + +# old obsolete way of calling fold() +my $struct = $seq1; # wierd way of allocating space +my $mfe=RNA::fold($seq1, $struct); +ok($struct, $struc1); + +# new better interface +($struct, $mfe) = RNA::fold($seq1); +ok($struct eq $struc1); +# check energy +ok(RNA::energy_of_struct($seq1,$struc1), $mfe); + +# check constrained folding +$RNA::fold_constrained = 1; +my($struct3, $cmfe) = RNA::fold($seq1, '....xx....xx...'); +ok($struct3, '(((..........)))'); +ok(RNA::energy_of_struct($seq1,$struct3), $cmfe); +$RNA::fold_constrained = 0; + +# test cofold +$RNA::cut_point = length($seq1)+1; +my($costruct, $comfe) = RNA::cofold($seq1 . $seq2); +ok($costruct, '(((.((....)).)))((((((...))).)))'); +$cmfe = RNA::energy_of_struct($seq1 . $seq2, $costruct); +ok(abs($comfe-$cmfe)<1e-5); +$RNA::cut_point=-1; + +# pf_fold +my $f = RNA::pf_fold($seq1, $struct); +ok(($f<$mfe)&&($mfe-$f<0.8)); + +# tree distance +my $xstruc = RNA::expand_Full($struc1); +my $T1 = RNA::make_tree($xstruc); +$xstruc = RNA::expand_Full($struc2); +my $T2 = RNA::make_tree($xstruc); +$RNA::edit_backtrack = 1; +my $tree_dist = RNA::tree_edit_distance($T1, $T2); +# print RNA::get_aligned_line(0), RNA::get_aligned_line(1),"\n"; +ok($tree_dist,4); + +# check access to a C array +#ok(RNA::ptrvalue($RNA::iindx,3),108); +ok(RNA::intP_getitem($RNA::iindx,3),108); + +#RNA::shortP_setitem($RNA::xsubi, 0, 171); +#RNA::shortP_setitem($RNA::xsubi, 1, 42); +#RNA::shortP_setitem($RNA::xsubi, 2, 93); +RNA::memmove($RNA::xsubi, pack('S3', 171,42,93)); +ok(pack('S3', 171,42,93), RNA::cdata($RNA::xsubi, 6)); + +# get a bp prob in two different ways +my $p1 = RNA::get_pr(2,15); +my $ii = RNA::intP_getitem($RNA::iindx, 2); +my $p2 = RNA::doubleP_getitem($RNA::pr, $ii-15); +ok(($p1<0.999) && ($p1>0.99) && (abs($p1-$p2)<1.2e-7)); + +my $bpf = RNA::Make_bp_profile(length($seq1)); +my @bpf = unpack("f*",RNA::cdata($bpf, length($seq1)*4*3)); +ok (($bpf[2*3]+$bpf[2*3+1]>.99999)&&$bpf[2*3+2]==0 && + ($bpf[2*3+1]>=$p1)); + +my $pack = RNA::pack_structure($struc1); +ok (RNA::unpack_structure($pack), $struc1); + + +RNA::parse_structure($struc1); +ok(($RNA::loops==2) && ($RNA::pairs==5)&&($RNA::unpaired==6) && + (RNA::intP_getitem($RNA::loop_degree,1)==2)); + + +RNA::PS_rna_plot($seq1, $struc1, "test_ss.ps"); +my $anote = "2 15 1 gmark\n" . "3 cmark\n"; +RNA::PS_rna_plot_a($seq1, $struc1, "test_ss_a.ps", undef, $anote); +RNA::PS_dot_plot($seq1, "test_dp.ps"); +RNA::ssv_rna_plot($seq1, $struct, "test.coord"); +# print "$seq1, $struct, $mfe, $f\n"; +print "please check the two postscript files test_ss.ps and test_dp.ps\n"; +RNA::write_parameter_file("test.par"); + +$RNA::symbolset = "GC"; +my $start = RNA::random_string(length $struc1, $RNA::symbolset); +my ($sinv, $cost) = RNA::inverse_fold($start, $struc1); +my ($ss, $en) = RNA::fold($sinv); +ok($ss, $struc1); + +RNA::free_pf_arrays(); +RNA::free_arrays(); + +$RNA::subopt_sorted = 1; +$RNA::noLonelyPairs = 1; +my $solution = RNA::subopt($seq1, undef, 500, undef); + +printf "%d suboptimals\n", $solution->size(); +for (0..$solution->size()) { + # the last access should produce a "value out of range" warning + printf "%s %6.2f\n", $solution->get($_)->{structure}, + $solution->get($_)->{energy} + if defined $solution->get($_); +} +$RNA::cut_point = 3; +my $e = RNA::energy_of_struct("GCGC", "(())"); +ok(int($e*100+0.5), 70); + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNALfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNALfold.Po new file mode 100755 index 00000000..4dcaeaf4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNALfold.Po @@ -0,0 +1,120 @@ +RNALfold.o RNALfold.o: RNALfold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAalifold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAalifold.Po new file mode 100755 index 00000000..1367f8ca --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAalifold.Po @@ -0,0 +1,129 @@ +RNAalifold.o RNAalifold.o: RNAalifold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/PS_dot.h ../H/utils.h ../config.h ../H/pair_mat.h \ + ../H/alifold.h ../H/aln_util.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/PS_dot.h: + +../H/utils.h: + +../config.h: + +../H/pair_mat.h: + +../H/alifold.h: + +../H/aln_util.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAcofold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAcofold.Po new file mode 100755 index 00000000..e1eaa698 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAcofold.Po @@ -0,0 +1,127 @@ +RNAcofold.o RNAcofold.o: RNAcofold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/PS_dot.h ../H/cofold.h ../H/fold.h \ + ../H/part_func_co.h ../H/part_func.h ../H/fold_vars.h ../H/utils.h \ + ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/PS_dot.h: + +../H/cofold.h: + +../H/fold.h: + +../H/part_func_co.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG.Po new file mode 100755 index 00000000..16926a85 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG.Po @@ -0,0 +1,121 @@ +RNAddG.o RNAddG.o: RNAddG.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/PS_dot.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/PS_dot.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG4.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG4.Po new file mode 100755 index 00000000..2eaaa922 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAddG4.Po @@ -0,0 +1,124 @@ +RNAddG4.o RNAddG4.o: RNAddG4.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/PS_dot.h ../H/utils.h ../config.h ../H/duplex.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/PS_dot.h: + +../H/utils.h: + +../config.h: + +../H/duplex.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAdistance.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAdistance.Po new file mode 100755 index 00000000..7ec96ad1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAdistance.Po @@ -0,0 +1,122 @@ +RNAdistance.o RNAdistance.o: RNAdistance.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/dist_vars.h ../H/RNAstruct.h \ + ../H/treedist.h ../H/stringdist.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/dist_vars.h: + +../H/RNAstruct.h: + +../H/treedist.h: + +../H/stringdist.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAduplex.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAduplex.Po new file mode 100755 index 00000000..121c5ba6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAduplex.Po @@ -0,0 +1,107 @@ +RNAduplex.o RNAduplex.o: RNAduplex.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/ctype.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/confname.h \ + /usr/include/getopt.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/duplex.h ../H/fold.h ../H/fold_vars.h \ + ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/duplex.h: + +../H/fold.h: + +../H/fold_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAeval.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAeval.Po new file mode 100755 index 00000000..b5739b89 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAeval.Po @@ -0,0 +1,118 @@ +RNAeval.o RNAeval.o: RNAeval.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold_vars.h ../H/fold.h ../H/utils.h \ + ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold_vars.h: + +../H/fold.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAfold.Po new file mode 100755 index 00000000..3eaa5148 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAfold.Po @@ -0,0 +1,122 @@ +RNAfold.o RNAfold.o: RNAfold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/PS_dot.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/PS_dot.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAheat.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAheat.Po new file mode 100755 index 00000000..f1ae7506 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAheat.Po @@ -0,0 +1,119 @@ +RNAheat.o RNAheat.o: RNAheat.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h ../H/utils.h \ + ../config.h ../H/fold_vars.h ../H/fold.h ../H/part_func.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +../H/utils.h: + +../config.h: + +../H/fold_vars.h: + +../H/fold.h: + +../H/part_func.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAinverse.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAinverse.Po new file mode 100755 index 00000000..ba74ed89 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAinverse.Po @@ -0,0 +1,122 @@ +RNAinverse.o RNAinverse.o: RNAinverse.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/inverse.h ../H/fold_vars.h ../H/fold.h \ + ../H/part_func.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/inverse.h: + +../H/fold_vars.h: + +../H/fold.h: + +../H/part_func.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po new file mode 100755 index 00000000..297871c4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po @@ -0,0 +1,122 @@ +RNAmotif_distance.o RNAmotif_distance.o: RNAmotif_distance.c \ + /usr/include/stdio.h /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/dist_vars.h ../H/RNAstruct.h \ + ../H/treedist.h ../H/stringdist.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/dist_vars.h: + +../H/RNAstruct.h: + +../H/treedist.h: + +../H/stringdist.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po~ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po~ new file mode 100755 index 00000000..7ec96ad1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAmotif_distance.Po~ @@ -0,0 +1,122 @@ +RNAdistance.o RNAdistance.o: RNAdistance.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/dist_vars.h ../H/RNAstruct.h \ + ../H/treedist.h ../H/stringdist.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/dist_vars.h: + +../H/RNAstruct.h: + +../H/treedist.h: + +../H/stringdist.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApaln.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApaln.Po new file mode 100755 index 00000000..46f257b2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApaln.Po @@ -0,0 +1,139 @@ +RNApaln.o RNApaln.o: RNApaln.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/errno.h /usr/include/bits/errno.h \ + /usr/include/linux/errno.h /usr/include/asm/errno.h \ + /usr/include/asm-x86_64/errno.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h ../H/part_func.h \ + ../H/fold.h ../H/fold_vars.h ../H/profiledist.h ../H/dist_vars.h \ + ../H/utils.h ../config.h ../H/ProfileAln.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/errno.h: + +/usr/include/bits/errno.h: + +/usr/include/linux/errno.h: + +/usr/include/asm/errno.h: + +/usr/include/asm-x86_64/errno.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +../H/part_func.h: + +../H/fold.h: + +../H/fold_vars.h: + +../H/profiledist.h: + +../H/dist_vars.h: + +../H/utils.h: + +../config.h: + +../H/ProfileAln.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApdist.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApdist.Po new file mode 100755 index 00000000..e93a96bf --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNApdist.Po @@ -0,0 +1,135 @@ +RNApdist.o RNApdist.o: RNApdist.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/errno.h /usr/include/bits/errno.h \ + /usr/include/linux/errno.h /usr/include/asm/errno.h \ + /usr/include/asm-x86_64/errno.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h ../H/part_func.h \ + ../H/fold_vars.h ../H/profiledist.h ../H/dist_vars.h ../H/utils.h \ + ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/errno.h: + +/usr/include/bits/errno.h: + +/usr/include/linux/errno.h: + +/usr/include/asm/errno.h: + +/usr/include/asm-x86_64/errno.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/profiledist.h: + +../H/dist_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplfold.Po new file mode 100755 index 00000000..cac72381 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplfold.Po @@ -0,0 +1,122 @@ +RNAplfold.o RNAplfold.o: RNAplfold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/part_func.h \ + ../H/fold_vars.h ../H/utils.h ../config.h ../H/PS_dot.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/part_func.h: + +../H/fold_vars.h: + +../H/utils.h: + +../config.h: + +../H/PS_dot.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplot.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplot.Po new file mode 100755 index 00000000..8735197e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAplot.Po @@ -0,0 +1,115 @@ +RNAplot.o RNAplot.o: RNAplot.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/confname.h \ + /usr/include/getopt.h ../H/utils.h ../config.h ../H/PS_dot.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +../H/utils.h: + +../config.h: + +../H/PS_dot.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAstats.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAstats.Po new file mode 100755 index 00000000..3950db63 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAstats.Po @@ -0,0 +1,122 @@ +RNAstats.o RNAstats.o: RNAstats.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/confname.h \ + /usr/include/getopt.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/part_func.h ../H/fold.h \ + ../H/fold_vars.h ../H/utils.h ../H/subopt.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/part_func.h: + +../H/fold.h: + +../H/fold_vars.h: + +../H/utils.h: + +../H/subopt.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAsubopt.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAsubopt.Po new file mode 100755 index 00000000..dfdadd9e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/.deps/RNAsubopt.Po @@ -0,0 +1,122 @@ +RNAsubopt.o RNAsubopt.o: RNAsubopt.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/confname.h \ + /usr/include/getopt.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/part_func.h ../H/fold.h \ + ../H/fold_vars.h ../H/utils.h ../H/subopt.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/part_func.h: + +../H/fold.h: + +../H/fold_vars.h: + +../H/utils.h: + +../H/subopt.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/Makefile new file mode 100755 index 00000000..08c498a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/Makefile @@ -0,0 +1,559 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# Progs/Makefile. 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNALfold.c new file mode 100755 index 00000000..7e7a723a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNALfold.c @@ -0,0 +1,247 @@ +/* Last changed Time-stamp: <2003-04-23 11:56:44 ivo> */ +/* + Ineractive Access to folding Routines + + c Ivo L Hofacker + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "part_func.h" +#include "fold_vars.h" +#include "utils.h" + +extern float Lfold(char *string, char *structure, int maxdist); +extern void read_parameter_file(const char fname[]); + +/*@unused@*/ +static char rcsid[] = "$Id: RNALfold.c,v 1.2 2003/07/14 13:38:47 ivo Exp $"; + +#define PRIVATE static + +static char scale1[] = "....,....1....,....2....,....3....,....4"; +static char scale2[] = "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *string, *line; + char *structure=NULL, *cstruc=NULL; + char fname[13], ffname[20], gfname[20]; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + int i, length, l, sym, r; + double energy, min_en; + double kT, sfact=1.07; + int pf=0, istty; + int noconv=0; + int maxdist=150; + + do_backtrack = 1; + string=NULL; + for (i=1; i : base i is paired with a base j>i\n"); + printf("matching brackets ( ): base i pairs base j\n"); + } + + do { /* main loop: continue until end of file */ + if (istty) { + printf("\nInput string (upper or lower case); @ to quit\n"); + printf("%s%s\n", scale1, scale2); + } + fname[0]='\0'; + if ((line = get_line(stdin))==NULL) break; + + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + if (*line=='>') + (void) sscanf(line, ">%12s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + string = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",string); + free(line); + length = (int) strlen(string); + + structure = (char *) space((unsigned) length+1); + if (fold_constrained) { + cstruc = get_line(stdin); + if (cstruc!=NULL) + strncpy(structure, cstruc, length); + else + fprintf(stderr, "constraints missing\n"); + } + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + if (istty) + printf("length = %d\n", length); + + /* initialize_fold(length); */ + update_fold_params(); + min_en = Lfold(string, structure, maxdist); + printf("%s\n%s", string, structure); + if (istty) + printf("\n minimum free energy = %6.2f kcal/mol\n", min_en); + else + printf(" (%6.2f)\n", min_en); + + (void) fflush(stdout); + + if (pf) { + + if (dangles==1) { + dangles=2; /* recompute with dangles as in pf_fold() */ + min_en = energy_of_struct(string, structure); + dangles=1; + } + + kT = (temperature+273.15)*1.98717/1000.; /* in Kcal */ + pf_scale = exp(-(sfact*min_en)/kT/length); + if (length>2000) fprintf(stderr, "scaling factor %f\n", pf_scale); + + init_pf_fold(length); + + if (cstruc!=NULL) + strncpy(structure, cstruc, length+1); + energy = pf_fold(string, structure); + + if (do_backtrack) { + printf("%s", structure); + if (!istty) printf(" [%6.2f]\n", energy); + else printf("\n"); + } + if ((istty)||(!do_backtrack)) + printf(" free energy of ensemble = %6.2f kcal/mol\n", energy); + printf(" frequency of mfe structure in ensemble %g\n", + exp((energy-min_en)/kT)); + + if (do_backtrack) { + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp.ps"); + } else strcpy(ffname, "dot.ps"); + /* (void) PS_dot_plot(string, ffname); */ + } + free_pf_arrays(); + + } + if (cstruc!=NULL) free(cstruc); + (void) fflush(stdout); + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE void usage(void) +{ + nrerror("usage:\n" + "RNALfold [-L span]\n" + " [-T temp] [-4] [-d[2|3]] [-noGU] [-noCloseGU]\n" + " [-noLP] [-P paramfile] [-nsp pairs] [-noconv]\n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNALfold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNALfold.o new file mode 100755 index 0000000000000000000000000000000000000000..187f0c0ff872b247261142f14063a0f73397b6e7 GIT binary patch literal 24896 zcmeHvdwd+lk$;cIkF_nleu4o9##jRRrH5bG#uy39_BxS4u`L0IwWk^ z99x{FfIh}XA-n=65OU|3BixVh%VEP2A{;D~%UzBf2S-)zvjUGd;83yQ*$=k!1-kmRKQj9HT<`DsyzTB&&rZJ|n(| z^dKIh(H{6$b4}pbgcg6bwcQ`oY^>@2q~W`0dqd#nw~s)* z^wSqcq9$U27ivqEAQR}WEkR~FGEh&Wy7q1$b{7v8gY?je+NHnwVoMiKuZfN& z^RjRIpRKm`4J_RE@$wy)b@vXHoIt&r1GObXO9%X&pY@?u;K0U`+Ccck+Wosvh^pRa zQDguQL;aaYmHz{ChM=JR-48_pTGus{@zr$?NwIZZANo7@gZ%eqz@h3L304gSy5%rx zI#$f9>jsINMhW46a(w3xGR-|5f0&zDAJ{Ji0^yeeLw!RhZY?hIKY4Z_{BML0o#-06 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+#include "part_func.h" +#include "fold_vars.h" +#include "PS_dot.h" +#include "utils.h" +#include "pair_mat.h" +#include "alifold.h" +#include "aln_util.h" +extern void read_parameter_file(const char fname[]); +/*@unused@*/ +static const char rcsid[] = "$Id: RNAalifold.c,v 1.13 2005/03/21 12:50:44 ivo Exp $"; + +#define PRIVATE static + +static const char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +PRIVATE void /*@exits@*/ usage(void); +PRIVATE char *annote(const char *structure, const char *AS[]); +PRIVATE void print_pi(const pair_info pi, FILE *file); +PRIVATE cpair *make_color_pinfo(const pair_info *pi); +PRIVATE void mark_endgaps(char *seq, char egap); +/*--------------------------------------------------------------------------*/ +#define MAX_NUM_NAMES 500 +int main(int argc, char *argv[]) +{ + char *string; + char *structure=NULL, *cstruc=NULL; + char ffname[20], gfname[20], fname[13]=""; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + int n_seq, i, length, sym, r; + int endgaps=0, mis=0; + double min_en, real_en, sfact=1.07; + int pf=0, istty; + char *AS[MAX_NUM_NAMES]; /* aligned sequences */ + char *names[MAX_NUM_NAMES]; /* sequence names */ + FILE *clust_file = stdin; + + do_backtrack = 1; + string=NULL; + dangles=2; + for (i=1; i : base i is paired with a base j>i\n"); + printf("matching brackets ( ): base i pairs base j\n"); + } + if (fold_constrained) { + if (istty) printf("%s\n", scale); + cstruc = get_line(stdin); + } + + if (istty && (clust_file == stdin)) { + printf("\nInput aligned sequences in clustalw format\n"); + if (!fold_constrained) printf("%s\n", scale); + } + + n_seq = read_clustal(clust_file, AS, names); + if (endgaps) + for (i=0; i2000) fprintf(stderr, "scaling factor %f\n", pf_scale); + fflush(stdout); + + /* init_alipf_fold(length); */ + + if (cstruc!=NULL) + strncpy(structure, cstruc, length+1); + energy = alipf_fold(AS, structure, &pi); + + if (do_backtrack) { + printf("%s", structure); + if (!istty) printf(" [%6.2f]\n", energy); + else printf("\n"); + } + if ((istty)||(!do_backtrack)) + printf(" free energy of ensemble = %6.2f kcal/mol\n", energy); + printf(" frequency of mfe structure in ensemble %g\n", + exp((energy-min_en)/kT)); + + if (do_backtrack) { + FILE *aliout; + cpair *cp; + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_ali.out"); + } else strcpy(ffname, "alifold.out"); + aliout = fopen(ffname, "w"); + if (!aliout) { + fprintf(stderr, "can't open %s skipping output\n", ffname); + } else { + short *ptable; int k; + ptable = make_pair_table(mfe_struc); + fprintf(aliout, "%d sequence; length of alignment %d\n", + n_seq, length); + fprintf(aliout, "alifold output\n"); + for (k=0; pi[k].i>0; k++) { + pi[k].comp = (ptable[pi[k].i] == pi[k].j) ? 1:0; + print_pi(pi[k], aliout); + } + fprintf(aliout, "%s\n", structure); + free(ptable); + } + fclose(aliout); + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp.ps"); + } else strcpy(ffname, "alidot.ps"); + cp = make_color_pinfo(pi); + (void) PS_color_dot_plot(string, cp, ffname); + free(cp); + } + free(mfe_struc); + free(pi); + } + if (cstruc!=NULL) free(cstruc); + free(base_pair); + (void) fflush(stdout); + free(string); + free(structure); + for (i=0; AS[i]; i++) { + free(AS[i]); free(names[i]); + } + return 0; +} + +void mark_endgaps(char *seq, char egap) { + int i,n; + n = strlen(seq); + for (i=0; i0 && (seq[i]=='-'); i--) { + seq[i] = egap; + } +} + +void print_pi(const pair_info pi, FILE *file) { + const char *pname[8] = {"","CG","GC","GU","UG","AU","UA", "--"}; + int i; + + /* numbering starts with 1 in output */ + fprintf(file, "%5d %5d %2d %5.1f%% %7.3f", + pi.i, pi.j, pi.bp[0], 100.*pi.p, pi.ent); + for (i=1; i<=7; i++) + if (pi.bp[i]) fprintf(file, " %s:%-4d", pname[i], pi.bp[i]); + /* if ((!pi.sym)&&(pi.j>=0)) printf(" *"); */ + if (!pi.comp) fprintf(file, " +"); + fprintf(file, "\n"); +} + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) + +PRIVATE cpair *make_color_pinfo(const pair_info *pi) { + cpair *cp; + int i, n; + for (n=0; pi[n].i>0; n++); + cp = (cpair *) space(sizeof(cpair)*(n+1)); + for (i=0; i0) { + snprintf(pps, 64, "%d %d %d gmark\n", i, j, pfreq[0]); + strcat(ps, pps); + } + if (vi>1) { + snprintf(pps, 64, "%d cmark\n", i); + strcat(ps, pps); + } + if (vj>1) { + snprintf(pps, 64, "%d cmark\n", j); + strcat(ps, pps); + } + } + free(ptable); + return ps; +} + +/*-------------------------------------------------------------------------*/ + +PRIVATE void usage(void) +{ + nrerror("usage:\n" + "RNAalifold [-cv float] [-nc float] [-E] [-mis]\n" + " [-p[0]] [-C] [-T temp] [-4] [-d] [-noGU] [-noCloseGU]\n" + " [-noLP] [-e e_set] [-P paramfile] [-nsp pairs] [-S scale]\n" + ); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAalifold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAalifold.o new file mode 100755 index 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100755 index 00000000..57276800 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAcofold.c @@ -0,0 +1,624 @@ +/* Last changed Time-stamp: <2006-01-19 11:49:34 ivo> */ +/* + c Ivo L Hofacker, Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "PS_dot.h" +#include "cofold.h" +#include "fold.h" +#include "part_func_co.h" +#include "part_func.h" +#include "fold_vars.h" +#include "utils.h" + +extern void read_parameter_file(const char fname[]); + +/*@unused@*/ +static char rcsid[] = "$Id: RNAcofold.c,v 1.6 2006/01/19 11:30:04 ivo Exp $"; + +#define PRIVATE static + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +PRIVATE char *costring(char *string); +PRIVATE char *tokenize(char *line); +PRIVATE void usage(void); +PRIVATE cofoldF do_partfunc(char *string, int length, int Switch, struct plist **tpr, struct plist **mf); +PRIVATE double *read_concentrations(FILE *fp); +PRIVATE void do_concentrations(double FEAB, double FEAA, double FEBB, double FEA, double FEB, double *startconces); +PRIVATE struct plist *get_mfe_plist(struct plist *pl); + +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *string, *line; + char *structure=NULL, *cstruc=NULL; + char fname[53], ffname[20]; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + char *Concfile; + int i, length, l, sym, r; + double min_en; + double kT, sfact=1.07; + int pf=0, istty; + int noconv=0; + int doT=0; /*compute dimere free energies etc.*/ + int doC=0; /*toggle to compute concentrations*/ + int doQ=0; /*toggle to compute prob of base being paired*/ + int cofi=0; /*toggle concentrations stdin / file*/ + struct plist *prAB; + struct plist *prAA; /*pair probabilities of AA dimer*/ + struct plist *prBB; + struct plist *prA; + struct plist *prB; + struct plist *mfAB; + struct plist *mfAA; /*pair mfobabilities of AA dimer*/ + struct plist *mfBB; + struct plist *mfA; + struct plist *mfB; + double *ConcAandB; + + do_backtrack = 1; + string=NULL; + Concfile=NULL; + for (i=1; i : base i is paired with a base j>i\n"); + printf("matching brackets ( ): base i pairs base j\n"); + } + + do { /* main loop: continue until end of file */ + cut_point = -1; + if (istty) { + printf("\nInput sequence(s); @ to quit\n"); + printf("Use '&' as spearator between 2 sequences that shall form a complex.\n"); + printf("%s\n", scale); + } + fname[0]='\0'; + if ((line = get_line(stdin))==NULL) break; + + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + if (*line=='>') + (void) sscanf(line, ">%51s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + string = tokenize(line); /* frees line */ + + length = (int) strlen(string); + if (doC) { + FILE *fp; + if (cofi) { /* read from file */ + fp = fopen(Concfile, "r"); + if (fp==NULL) { + fprintf(stderr, "could not open concentration file %s", Concfile); + nrerror("\n"); + } + ConcAandB = read_concentrations(fp); + fclose(fp); + } else { + printf("Please enter concentrations [mol/l]\n format: ConcA ConcB\n return to end\n"); + ConcAandB = read_concentrations(stdin); + } + } + + structure = (char *) space((unsigned) length+1); + if (fold_constrained) { + cstruc = tokenize(get_line(stdin)); + if (cstruc!=NULL) + strncpy(structure, cstruc, length); + else + fprintf(stderr, "constraints missing\n"); + } + + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + if (istty) { + if (cut_point == -1) + printf("length = %d\n", length); + else + printf("length1 = %d\nlength2 = %d\n", + cut_point-1, length-cut_point+1); + } + + /*compute mfe of AB dimer*/ + min_en = cofold(string, structure); + mfAB=(struct plist *) space(sizeof(struct plist) * (length+1)); + mfAB=get_mfe_plist(mfAB); + + if (cut_point == -1) printf("%s\n%s", string, structure); /*no cofold*/ + + else { + char *pstring, *pstruct; + pstring = costring(string); + pstruct = costring(structure); + printf("%s\n%s", pstring, pstruct); + free(pstring); + free(pstruct); + } + if (istty) + printf("\n minimum free energy = %6.2f kcal/mol\n", min_en); + else + printf(" (%6.2f)\n", min_en); + + (void) fflush(stdout); + + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_ss.ps"); + } else { + strcpy(ffname, "rna.ps"); + } + if (length<2000) + (void) PS_rna_plot(string, structure, ffname); + else { + fprintf(stderr,"INFO: structure too long, not doing xy_plot\n"); + free_co_arrays(); + } + + /*compute partition function*/ + if (pf) { + cofoldF AB, AA, BB; + if (dangles==1) { + dangles=2; /* recompute with dangles as in pf_fold() */ + min_en = energy_of_struct(string, structure); + dangles=1; + } + + kT = (temperature+273.15)*1.98717/1000.; /* in Kcal */ + pf_scale = exp(-(sfact*min_en)/kT/length); + if (length>2000) fprintf(stderr, "scaling factor %f\n", pf_scale); + + init_co_pf_fold(length); + + if (cstruc!=NULL) + strncpy(structure, cstruc, length+1); + AB = co_pf_fold(string, structure); + + if (do_backtrack) { + char *costruc; + costruc = (char *) space(sizeof(char)*(strlen(structure)+2)); + if (cut_point<0) printf("%s", structure); + else { + strncpy(costruc, structure, cut_point-1); + strcat(costruc, "&"); + strcat(costruc, structure+cut_point-1); + printf("%s", costruc); + } + if (!istty) printf(" [%6.2f]\n", AB.FAB); + else printf("\n");/*8.6.04*/ + } + if ((istty)||(!do_backtrack)) + printf(" free energy of ensemble = %6.2f kcal/mol\n", AB.FAB); + printf(" frequency of mfe structure in ensemble %g", + exp((AB.FAB-min_en)/kT)); + + printf(" , delta G binding=%6.2f\n", AB.FcAB - AB.FA - AB.FB); + + prAB=(struct plist *) space(sizeof(struct plist) * (2*length)); + prAB=get_plist(prAB, length,0.00001); + + /* if (doQ) make_probsum(length,fname); */ /*compute prob of base paired*/ + free_co_arrays(); + if (doT) { /* cofold of all dimers, monomers */ + int Blength, Alength; + char *Astring, *Bstring; + char *Newstring; + char Newname[30]; + char comment[80]; + if (cut_point<0) { + printf("Sorry, i cannot do that with only one molecule, please give me two or leave it\n"); + free(mfAB); + free(prAB); + continue; + } + if (dangles==1) dangles=2; + Alength=cut_point-1; /*length of first molecule*/ + Blength=length-cut_point+1; /*length of 2nd molecule*/ + + Astring=(char *)space(sizeof(char)*(Alength+1));/*Sequence of first molecule*/ + Bstring=(char *)space(sizeof(char)*(Blength+1));/*Sequence of second molecule*/ + strncat(Astring,string,Alength); + strncat(Bstring,string+Alength,Blength); + + /* compute AA dimer */ + prAA=(struct plist *) space(sizeof(struct plist) * (4*Alength)); + mfAA=(struct plist *) space(sizeof(struct plist) * (Alength+1)); + AA=do_partfunc(Astring, Alength, 2, &prAA, &mfAA); + /* compute BB dimer */ + prBB=(struct plist *) space(sizeof(struct plist) * (4*Blength)); + mfBB=(struct plist *) space(sizeof(struct plist) * (Blength+1)); + BB=do_partfunc(Bstring, Blength, 2, &prBB, &mfBB); + /*free_co_pf_arrays();*/ + + /* compute A monomer */ + prA=(struct plist *) space(sizeof(struct plist) * (2*Alength)); + mfA=(struct plist *) space(sizeof(struct plist) * (Alength+1)); + do_partfunc(Astring, Alength, 1, &prA, &mfA); + + /* compute B monomer */ + prB=(struct plist *) space(sizeof(struct plist) * (2*Blength)); + mfB=(struct plist *) space(sizeof(struct plist) * (Blength+1)); + do_partfunc(Bstring, Blength, 1, &prB, &mfB); + + compute_probabilities(AB.F0AB, AB.FA, AB.FB, prAB, prA, prB, Alength); + compute_probabilities(AA.F0AB, AA.FA, AA.FA, prAA, prA, prA, Alength); + compute_probabilities(BB.F0AB, BB.FA, BB.FA, prBB, prA, prB, Blength); + printf("Free Energies:\nAB\t\tAA\t\tBB\t\tA\t\tB\n%.6f\t%6f\t%6f\t%6f\t%6f\n", + AB.FcAB, AA.FcAB, BB.FcAB, AB.FA, AB.FB); + + if (doC) { + do_concentrations(AB.FcAB, AA.FcAB, BB.FcAB, AB.FA, AB.FB, ConcAandB); + free(ConcAandB);/*freeen*/ + } + + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp5.ps"); + } else strcpy(ffname, "dot5.ps"); + /*output of the 5 dot plots*/ + + /*AB dot_plot*/ + /*write Free Energy into comment*/ + sprintf(comment,"\n%%Heterodimer AB FreeEnergy= %.9f\n", AB.FcAB); + /*reset cut_point*/ + cut_point=Alength+1; + /*write New name*/ + strcpy(Newname,"AB"); + strcat(Newname,ffname); + (void)PS_dot_plot_list(string, Newname, prAB, mfAB, comment); + + /*AA dot_plot*/ + sprintf(comment,"\n%%Homodimer AA FreeEnergy= %.9f\n",AA.FcAB); + /*write New name*/ + strcpy(Newname,"AA"); + strcat(Newname,ffname); + /*write AA sequence*/ + Newstring=(char*)space((2*Alength+1)*sizeof(char)); + strcpy(Newstring,Astring); + strcat(Newstring,Astring); + (void)PS_dot_plot_list(Newstring, Newname, prAA, mfAA, comment); + free(Newstring); + + /*BB dot_plot*/ + sprintf(comment,"\n%%Homodimer BB FreeEnergy= %.9f\n",BB.FcAB); + /*write New name*/ + strcpy(Newname,"BB"); + strcat(Newname,ffname); + /*write BB sequence*/ + Newstring=(char*)space((2*Blength+1)*sizeof(char)); + strcpy(Newstring,Bstring); + strcat(Newstring,Bstring); + /*reset cut_point*/ + cut_point=Blength+1; + (void)PS_dot_plot_list(Newstring, Newname, prBB, mfBB, comment); + free(Newstring); + + /*A dot plot*/ + /*reset cut_point*/ + cut_point=-1; + sprintf(comment,"\n%%Monomer A FreeEnergy= %.9f\n",AB.FA); + /*write New name*/ + strcpy(Newname,"A"); + strcat(Newname,ffname); + /*write BB sequence*/ + (void)PS_dot_plot_list(Astring, Newname, prA, mfA, comment); + + /*B monomer dot plot*/ + sprintf(comment,"\n%%Monomer B FreeEnergy= %.9f\n",AB.FB); + /*write New name*/ + strcpy(Newname,"B"); + strcat(Newname,ffname); + /*write BB sequence*/ + (void)PS_dot_plot_list(Bstring, Newname, prB, mfB, comment); + free(Astring); free(Bstring); free(prAB); free(prAA); free(prBB); free(prA); free(prB); + free(mfAB); free(mfAA); free(mfBB); free(mfA); free(mfB); + + } /*end if(doT)*/ + + }/*end if(pf)*/ + + + if (do_backtrack) { + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp.ps"); + } else strcpy(ffname, "dot.ps"); + + if (!doT) { + if (pf) { (void) PS_dot_plot_list(string, ffname, prAB, mfAB, "doof"); + free(prAB);} + free(mfAB); + } + } + if (!doT) free_co_pf_arrays(); + + + if (cstruc!=NULL) free(cstruc); + (void) fflush(stdout); + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE char *tokenize(char *line) +{ + char *pos, *copy; + int cut = -1; + + copy = (char *) space(strlen(line)+1); + (void) sscanf(line, "%s", copy); + pos = strchr(copy, '&'); + if (pos) { + cut = (int) (pos-copy)+1; + if (cut >= strlen(copy)) cut = -1; + if (strchr(pos+1, '&')) nrerror("more than one cut-point in input"); + for (;*pos;pos++) *pos = *(pos+1); /* splice out the & */ + } + if (cut > -1) { + if (cut_point==-1) cut_point = cut; + else if (cut_point != cut) { + fprintf(stderr,"cut_point = %d cut = %d\n", cut_point, cut); + nrerror("Sequence and Structure have different cut points."); + } + } + free(line); + return copy; +} + +PRIVATE char *costring(char *string) +{ + char *ctmp; + int len; + + len = strlen(string); + ctmp = (char *)space((len+2) * sizeof(char)); + /* first sequence */ + (void) strncpy(ctmp, string, cut_point-1); + /* spacer */ + ctmp[cut_point-1] = '&'; + /* second sequence */ + (void) strcat(ctmp, string+cut_point-1); + + return ctmp; +} + +PRIVATE cofoldF do_partfunc(char *string, int length, int Switch, struct plist **tpr, struct plist **mfpl) { + /*compute mfe and partition function of dimere or monomer*/ + char *Newstring; + char *tempstruc; + double min_en; + double sfact=1.07; + double kT; + cofoldF X; + kT = (temperature+273.15)*1.98717/1000.; + switch (Switch) + { + case 1: /*monomer*/ + cut_point=-1; + tempstruc = (char *) space((unsigned)length+1); + min_en = fold(string, tempstruc); + pf_scale = exp(-(sfact*min_en)/kT/(length)); + *mfpl=get_mfe_plist(*mfpl); + free_arrays(); + /*En=pf_fold(string, tempstruc);*/ + init_co_pf_fold(length); + X=co_pf_fold(string, tempstruc); + + *tpr=get_plist(*tpr, length,0.00001); + free_co_pf_arrays(); + free(tempstruc); + break; + + case 2: /*dimer*/ + Newstring=(char *)space(sizeof(char)*(length*2+1)); + strcat(Newstring,string); + strcat(Newstring,string); + cut_point=length+1; + tempstruc = (char *) space((unsigned)length*2+1); + min_en = cofold(Newstring, tempstruc); + pf_scale =exp(-(sfact*min_en)/kT/(2*length)); + *mfpl=get_mfe_plist(*mfpl); + free_co_arrays(); + init_co_pf_fold(2*length); + X=co_pf_fold(Newstring, tempstruc); + *tpr=get_plist(*tpr, 2*length,0.00001); + free_co_pf_arrays(); + free(Newstring); + free(tempstruc); + break; + + default: + printf("Error in get_partfunc\n, computing neither mono- nor dimere!\n"); + exit (42); + + } + return X; +} + + +PRIVATE void do_concentrations(double FEAB, double FEAA, double FEBB, double FEA, double FEB, double *startconc) { + /* compute and print concentrations out of free energies, calls get_concentrations */ + struct ConcEnt *result; + int i, n; + + result=get_concentrations(FEAB, FEAA, FEBB, FEA, FEB, startconc); + + printf("Initial concentrations\t\trelative Equilibrium concentrations\n"); + printf("A\t\t B\t\t AB\t\t AA\t\t BB\t\t A\t\t B\n"); + for (n=0; (startconc[2*n]>0) || (startconc[2*n+1]>0); n++); /* count */ + for (i=0; i=2*n) { + n*=2; + startc=(double *)xrealloc(startc,(2*n+1)*sizeof(double)); + } + c = sscanf(line,"%lf %lf", &startc[i], &startc[i+1]); + free(line); + if (c<2) break; + i+=2; + } + startc[i]=startc[i+1]=0; + return startc; +} + +static struct plist *get_mfe_plist(struct plist *pl) { + /*get list of mfe structure out of base_pairs array*/ + int l; + for(l=1; l<=base_pair[0].i; l++) + { + pl[l-1].i=base_pair[l].i; + pl[l-1].j=base_pair[l].j; + pl[l-1].p=0.95; + } + pl[l-1].i=0; + pl[l-1].j=0; + pl[l-1].p=0.; + pl=(struct plist *)xrealloc(pl,l*sizeof(struct plist)); + return pl; +} + + +PRIVATE void usage(void) +{ + nrerror("usage:\n" + "RNAcofold [-a] [-c] [-f concfile]\n" + "[-p[0]] [-C] [-T temp] [-4] [-d[2|3]] [-noGU] [-noCloseGU]\n" + "[-noLP] [-e e_set] [-P paramfile] [-nsp pairs] [-S scale] " + "[-noconv]\n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAcofold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAcofold.o new file mode 100755 index 0000000000000000000000000000000000000000..7156ed19b7142f811f1aac9b2e993179df03263f GIT binary patch literal 47968 zcmeIbdwf*Y)jxb@Cg2c4CITwnaF752AtVSGB4Q>4m|&D>E}#TLm`os=Wa7+(iy}lx zEK>;Lt+k4+y;*8+_Gzo2{xphQ+G>lnDs62Ai<%TIc&Wx#&AZm#Yn@p+b56_C-}~45 zdG{wdXYKD^d+oK?Ui)(Pxy+_{W%J!Gm%+hh%rTNNMh&BHRgx}JWRc-F&NrSxx)%=( z4Ljg3m}tsAQU-^UWr=upUocUVeYiC7MOmUgyC=B$-JBj|?ONwj=ch3eOgvYb*jJYL 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--git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAddG4.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAddG4.c new file mode 100755 index 00000000..1a740b8d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAddG4.c @@ -0,0 +1,402 @@ +/* Last changed Time-stamp: <2005-09-22 10:10:55 ivo> */ +/* + * Ineractive Access to folding Routines + * + * c Ivo L Hofacker Vienna RNA package + */ + +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "part_func.h" +#include "fold_vars.h" +#include "PS_dot.h" +#include "utils.h" +#include "duplex.h" + +static void print_struc(duplexT const *dup); +double LogOfSumOfExps (double* exps, int num_exps); + +/* @unused@ */ +static char rcsid[] = "$Id: RNAfold.c,v 1.18 2005/10/30 20:07:12 ivo Exp $"; + +#define PRIVATE static +#define MIN_NUMBER_TO_EXPONENTIATE -100 + +static char scale1[] = "....,....1....,....2....,....3....,....4"; +static char scale2[] = "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + + +int array_size_i = 0; +int array_size_j = 0; +int *array_i; +int *array_j; +int five_prime_length = 0; +int E5p, E3p; +int debug_mode = 0; + +/*--------------------------------------------------------------------------*/ + +int +main(int argc, char *argv[]) +{ + char *string, *line; + char *structure = NULL, *constraint = NULL, *sub_target = NULL; + char *ParamFile = NULL; + char *ns_bases = NULL, *c; + int i, length, l, sym, r; + double energy, min_en; + double kT, sfact = 1.07; + int noconv = 0; + + duplexT hybrid; + + double dG0, dG1, dG2, P; + double ddG[50]; + double dG1array[50]; + double dG2array[50]; + + int n_exps = 0; + + + int restrict_from = 0; /* Where to start and end restriction of */ + int restrict_to = 0; /* mRNA folding so that miRNA can bind */ + int target_start = 0; /* Base where target starts */ + int upstream_rest = 0; /* Number of bases to be restricted upstream of target */ + + string = NULL; + for (i = 1; i < argc; i++) { + if (argv[i][0] == '-') + switch (argv[i][1]) { + case 'T': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%lf", &temperature); + if (!r) + usage(); + break; + case 'n': + if (strcmp(argv[i], "-noGU") == 0) + noGU = 1; + if (strcmp(argv[i], "-noCloseGU") == 0) + no_closingGU = 1; + if (strcmp(argv[i], "-noLP") == 0) + noLonelyPairs = 1; + if (strcmp(argv[i], "-nsp") == 0) { + if (i == argc - 1) + usage(); + ns_bases = argv[++i]; + } + if (strcmp(argv[i], "-noconv") == 0) + noconv = 1; + break; + case '4': + tetra_loop = 0; + break; + case 'e': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%d", &energy_set); + if (!r) + usage(); + break; + + case 'f': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%i", &restrict_from); + if (!r) + usage(); + break; + + case 't': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%i", &restrict_to); + if (!r) + usage(); + break; + + case 's': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%i", &target_start); + if (!r) + usage(); + target_start--; /* zero-based */ + break; + + case 'u': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%i", &upstream_rest); + if (!r) + usage(); + break; + + case 'S': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%lf", &sfact); + if (!r) + usage(); + break; + case 'd': + dangles = 0; + if (argv[i][2] != '\0') { + r = sscanf(argv[i] + 2, "%d", &dangles); + if (r != 1) + usage(); + } + break; + case 'P': + if (i == argc - 1) + usage(); + ParamFile = argv[++i]; + break; + default: + usage(); + } + } + + if (ParamFile != NULL) + read_parameter_file(ParamFile); + + if (ns_bases != NULL) { + nonstandards = space(33); + c = ns_bases; + i = sym = 0; + if (*c == '-') { + sym = 1; + c++; + } + while (*c != '\0') { + if (*c != ',') { + nonstandards[i++] = *c++; + nonstandards[i++] = *c; + if ((sym) && (*c != *(c - 1))) { + nonstandards[i++] = *c; + nonstandards[i++] = *(c - 1); + } + } + c++; + } + } + + /* Some global parameters for the folding routines */ + do_backtrack = 0; + dangles = 2; + fold_constrained = 0; + + /* main loop: continue until end of file */ + + do { + + n_exps = 0; + + /* Read and prepare sequence ***************************/ + + if ((line = get_line(stdin)) == NULL) + break; + + string = (char *) space(strlen(line) + 1); + (void) sscanf(line, "%s", string); + free(line); + length = (int) strlen(string); + + structure = (char *) space((unsigned) length + 1); + constraint = (char *) space((unsigned) length + 1); + + sub_target = (char *) space(restrict_to + 1); + + + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') + string[l] = 'U'; + } + + /* Fold with no constraint ********************************************/ + + min_en = fold(string, structure); + printf ("%s\t", structure); + + fold_constrained = 0; + + kT = (temperature + 273.15) * 1.98717 / 1000.; /* in Kcal */ + pf_scale = exp(-(sfact * min_en) / kT / length); + init_pf_fold(length); + + dG0 = pf_fold(string, structure); + + free_pf_arrays(); + + /* Create constraint sequence from length restrict_from to restrict_to */ + /* and calculate the fold for each constrain */ + + int i,j; + + for (i = restrict_from; i <= restrict_to; i++) + { + /* Build constraint string */ + + memset (constraint, ' ', length); + + for (j = (target_start + upstream_rest); j > (target_start - i); j--) + { + constraint[j] = 'x'; + } + + /* for (j = 0 - upstream_rest; j < i; j++) + { + constraint[j+target_start] = 'x'; + }*/ + + if (i < restrict_to) + constraint[target_start-i] = '|'; + + fold_constrained = 1; + strncpy(structure, constraint, length + 1); + + /* printf ("%d (from=%d; to=%d; upstream=%d): Constraint is: **%s**\n", i, restrict_from, restrict_to, upstream_rest, structure); */ + + /* Fold with constraint *******************************************/ + + min_en = fold(string, structure); + printf ("%s", structure); + if (i < restrict_to) + printf (";"); + + pf_scale = exp(-(sfact * min_en) / kT / length); + init_pf_fold(length); + + strncpy(structure, constraint, length + 1); + dG1 = pf_fold(string, structure); + + /* Call RNAduplex to calculate the hybridization energy */ + + /* strncpy (sub_target, string+target_start, i); + sub_target[i]='\x0'; */ + + + update_fold_params(); + + /* For future use: calcualte pf-like by summing many suboptimal structs + if (delta>=0) { + duplexT *sub; + subopt = duplex_subopt(s1, s2, delta, 0); + for (sub=subopt; sub->i >0; sub++) { + print_struc(sub); + free(sub->structure); + } + free(subopt); + } + */ + + /* hybrid = duplexfold(sub_target, miRNA); + /* print_struc(&hybrid); + free(hybrid.structure); */ + + printf ("\tno_hybrid_struct"); + + dG2 = 0; /*hybrid.energy; */ + + dG1array[n_exps] = dG1; + dG2array[n_exps] = dG2; + + ddG[n_exps++] = - (dG1 + dG2 - dG0); + /* printf ("dG0=%g, dG1=%g, dG2=%g, ddG=%g\t", dG0, dG1, dG2, -ddG[n_exps-1]); */ + } + + double ddGsum = -LogOfSumOfExps (ddG, n_exps); + + P = 1 / ( 1 + exp(ddGsum / kT) ); /* Probability of being bound */ + + printf ("\t%g\t", dG0); + + for (i=0; i= 2000) free(base_pair); + (void) fflush(stdout); + free(string); + free(structure); + free(constraint); + } while (1); + return 0; +} + +static void print_struc(duplexT const *dup) { + int l1; + l1 = strchr(dup->structure, '&')-dup->structure; + printf("%s %3d,%-3d : %3d,%-3d (%5.2f)\n", dup->structure, dup->i+1-l1, + dup->i, dup->j, dup->j+strlen(dup->structure)-l1-2, dup->energy); +} + + +double LogOfSumOfExps (double* exps, int num_exps) +{ + + // compute log(exp(a_1)+exp(a_2)+...exp(a_n)) using: + // max(a_1,a_2,..a_n) + log(1+exp(a_2-max(a_1,a_2,..a_n))+...exp(a_n-max(a_1,a_2,..a_n))) + + double max_index = 0; + double max = exps[0]; + int i; + + for (i = 1; i < num_exps; ++i) + { + if (exps[i] > max) + { + max = exps[i]; + max_index = i; + } + } + + double remaining_summand = 1.0; + for (i = 0; i < num_exps; ++i) + { + if (i != max_index) + { + double difference = exps[i] - max; + if (difference > MIN_NUMBER_TO_EXPONENTIATE) + remaining_summand += exp(difference); + } + } + + double result = max + log(remaining_summand); + + return result; +} + + +PRIVATE void +usage(void) +{ + nrerror("usage:\n" + "RNAfold [-p[0]] [-C] [-T temp] [-4] [-d[2|3]] [-noGU] [-noCloseGU]\n" + " [-noLP] [-e e_set] [-P paramfile] [-nsp pairs] [-S scale]\n" + " [-noconv] \n\n" + " RNAddG special switches:\n" + " -f \n" + " -t \n" ); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance new file mode 100755 index 0000000000000000000000000000000000000000..ee7546539455247b8d08e05b5c0b446d8f57c126 GIT binary patch literal 114868 zcmeFa3w%`7^)G&AGD8LkIROGj2{@7g6CROZ&;&xA2@{y;fT;w<0zw!P2!(yEneYqc-6wP>v+34sJq5%Gm0itjT91hry(&j0(}=bU5`(YE$;@BiNW 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance.c new file mode 100755 index 00000000..40022eb9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance.c @@ -0,0 +1,548 @@ +/* + Distances of Secondary Structures + Walter Fontana, Ivo L Hofacker, Peter F Stadler + Vienna RNA Package +*/ +#include +#include +#include +#include +#include +#include +#include "dist_vars.h" +#include "RNAstruct.h" +#include "treedist.h" +#include "stringdist.h" +#include "utils.h" + +#define MAXNUM 1000 /* max number of structs for distance matrix */ + +#define PUBLIC +#define PRIVATE static +/*@unused@*/ +static char rcsid[] = "$Id: RNAdistance.c,v 1.8 2005/07/24 08:35:15 ivo Exp $"; +PRIVATE void command_line(int argc, char *argv[]); +PRIVATE void usage(void); +PRIVATE int parse_input(char *line); +PRIVATE int check_tree(char *line, char alpha[]); +PRIVATE int check_brackets(char *line); +PRIVATE void print_aligned_lines(FILE *somewhere); + +PRIVATE char ruler[] ="....,....1....,....2....,....3....,....4" +"....,....5....,....6....,....7....,....8"; +PRIVATE int types=1; +PRIVATE int task; +PRIVATE int taxa_list; +PRIVATE char outfile[50], *list_title; + +PRIVATE char ttype[10]="f"; +PRIVATE int n=0; + +int main(int argc, char *argv[]) +{ + char *line=NULL, *xstruc, *cc; + Tree *T[10][MAXNUM]; + int tree_types = 0, ttree; + swString *S[10][MAXNUM]; + char *P[MAXNUM]; /* structures for base pair distances */ + int string_types = 0, tstr; + int i,j, tt, istty, type; + int it, is; + FILE *somewhere=NULL; + + command_line(argc, argv); + + if((outfile[0]=='\0')&&(task==2)&&(edit_backtrack)) + strcpy(outfile,"backtrack.file"); + if(outfile[0]!='\0') somewhere = fopen(outfile,"w"); + if (somewhere==NULL) somewhere = stdout; + istty = isatty(fileno(stdin))&&isatty(fileno(stdout)); + + do { + if ((istty)&&(n==0)) { + printf("\nInput structure; @ to quit\n"); + printf("%s\n", ruler); + } + do { + if (line!=NULL) free(line); + line=get_line(stdin); + } while ((type=parse_input(line))==0); + + if (((type==999)||(type==888))&&(task==2)) { /* do matrices */ + if (taxa_list) + printf("* END of taxa list\n"); + + ttree = 0; tstr = 0; + for (tt=0; tt< types; tt++) { + printf("> %c %d\n", ttype[tt], n); + if(islower(ttype[tt])) { + for (i=1; i1) { + for (it=0, is=0, i=0; i1) { + for (it=0, is=0, i=0; i') { + if (taxa_list) + printf("%d :%s\n", n+1, line+1); + else printf("%s\n", line); + return 0; + } + + cp = strchr(line,' '); + if (cp) *cp='\0'; /* get rid of junk at the end of line */ + + switch (line[0]) { + case '.' : + type = 1; + break; + + case '(' : /* it's a tree */ + i=1; + xx = 0; + type = 4; /* coarse */ + rooted = 0; + while (line[i]) { + if (line[i]=='.'){ + type = 1; /* Full */ + break; + } + if ( (line[i]=='U')||(line[i]=='P') ) { + type = 2; /* FFull */ + xx = 1; + break; + } + if (line[i]=='S') { + type = 3; + xx = 1; + break; /* Shapiro tree */ + } + if ((line[i]!='(')&&(line[i]!=')')) xx = 1; + i++; + } + if(!xx) type =1; + + rooted = (line[strlen(line)-2]=='R'); + break; + case '@' : + return 999; + + default: + return 0; + } + + switch (type) { + case 1: + if(check_brackets(line)) + return 1; + break; + case 2: + if(check_tree(line,"UP") ) { + if(rooted) return 2; + else return -2; + } + break; + case 3: + if(check_tree(line,"HBIMSE") ){ + if(rooted) return -3; + else return -3; + } + break; + case 4: + if(check_tree(line,"HBIM") ){ + if(rooted) return 4; + else return -4; + } + break; + } + return 0; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE int check_tree(char *line, char alpha[]) +{ + int n, i, o; + char *pos; + + n = (int) strlen(line); + + if( line[0] != '(' ) return 0; + i=o=1; + while( line[i] ){ + while( line[i] == '(' ){ + o++; + i++; + } + pos=strchr(alpha, (int)line[i]); + if (pos) { + while (isdigit((int) line[++i])); + if (line[i]!=')') return 0; + } + if (line[i]=='R') { + i++; + if ((i!=n-1)||(line[i]!=')')) return 0; + } + if (line[i]==')') { + o--; + if(o< 0) return 0; + if( (i0) return 0; + return 1; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE int check_brackets(char *line) +{ + int i,o; + + i=o=0; + while( line[i] ){ + switch(line[i]) { + case '(' : + o++; + i++; + break; + case '.' : + i++; + break; + case ')' : + i++; + o--; + if(o<0) return 0; + break; + default: + return 0; + } + } + if (o>0) return 0; + return 1; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE void command_line(int argc, char *argv[]) +{ + int i; + + edit_backtrack = 0; + types=1; ttype[0]='f'; task=1; + + for (i=1; i= argc) outfile[0] = '\0'; + else if (argv[i+1][0]=='-') outfile[0] = '\0'; + else { + i++; + strncpy(outfile,argv[i],49); + } + edit_backtrack = 1; + break; + default: + usage(); + } + } +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void print_aligned_lines(FILE *somewhere) +{ + if (edit_backtrack) { + fprintf(somewhere, "\n%s\n%s\n", aligned_line[0], aligned_line[1]); + fflush(somewhere); + } +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void usage(void) +{ + nrerror("usage: RNAdistance [-D[fhwcFHWCP]] [-X[p|m|f|c]] [-S] [-B [file]]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAdistance.o new file mode 100755 index 0000000000000000000000000000000000000000..f6f5225c6408c6714dc6e8282dc70d8475fb0431 GIT binary patch literal 36552 zcmeHw33!y%_4hmTCO8nx1W<_zI+CDaO9&z+h?+oviCZICKqbb>WCAH6iIa(78zh=U zjUf=Nwe%0RwrbtF*j9zQU|hiE>!Mbzt+k3>B&`TmYjNv*=iGbF`<~pHvD)YPmjCyB z_aXD1`@83!d+s^so_pVS7B((EXNlM2vAB4wGc32psAa7<-=#|wSz;Y$9c%TcW2G|K z_i^t~hxeik-JW81=EeNM?k9a0)t0U-tu4K{wC;)0uFhPKRr(0(sa_sJ%HOjI 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zhJ?6vocz;olXRa99J{C% zBh-iN&_~mkpd6L(^b*Zo8_lKRk^;L{p_rynNt!jhAM%4z{{F$ky*-2e;eGpt`$qhc zp5DPeOmoTEzK<-6XasveQ^#!E+(wU1`Eea%0A{4ib0eO&NDxw;X`h31NyO(V8@%SE z2pQLX8jq<|R$sL?SgVHR=^-Akd`{dl*4Yppi+s#t(}1Qf#aiShWojkNBD16=o>NkW z;IYB4Cx|38Y#28TUDVLs */ +/* + Compute duplex structure of two RNA strands + + c Ivo L Hofacker + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include "duplex.h" +#include "fold.h" +#include "fold_vars.h" +#include "utils.h" + +extern void read_parameter_file(const char fname[]); +extern int subopt_sorted; +static void print_struc(duplexT const *dup); +void parse_mapping_array (int **map_array, int *array_size, char *arguments_string); + +/*@unused@*/ +static char rcsid[] = "$Id: RNAduplex.c,v 1.4 2005/07/24 08:35:15 ivo Exp $"; + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +static void usage(void); + +#define PRIVATE static + +int array_size_i = 0; +int array_size_j = 0; +int *array_i = NULL; +int *array_j = NULL; +int five_prime_length = 0; +int auto_five_prime_length = 0; +int E5p, E3p; +int debug_mode = 0; +int all_pairs = 0; + +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *s1, *s2, *line; + char fname[13]; + char tmp_string[255]; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + int i, l, sym, r; + double deltaf; + double kT, sfact=1.07; + int pf=0, istty, delta=-1; + int noconv=0; + int l1, l2; + + for (i=1; i=argc-1) usage(); + r=sscanf(argv[++i], "%lf", &deltaf); + if (r!=1) usage(); + delta = (int) (0.1+deltaf*100); + break; + case 's': subopt_sorted=1; + break; + case 'i': + if (i>=argc-1) usage(); + r=sscanf(argv[++i], "%s", tmp_string); + if (r!=1) usage(); + + parse_mapping_array (&array_i, &array_size_i, tmp_string); + break; + + case 'j': + if (i>=argc-1) usage(); + r=sscanf(argv[++i], "%s", tmp_string); + if (r!=1) usage(); + + parse_mapping_array (&array_j, &array_size_j, tmp_string); + break; + + case '5': + if (i>=argc-1) usage(); + r=sscanf(argv[++i], "%d", &five_prime_length); + if (r!=1) usage(); + if (five_prime_length == 0) auto_five_prime_length = 1; + break; + + case 'D': + if (i>=argc-1) usage(); + r=sscanf(argv[++i], "%d", &debug_mode); + if (r!=1) usage(); + break; + + case 'a': + if (i>=argc-1) usage(); + r=sscanf(argv[++i], "%d", &all_pairs); + if (r!=1) usage(); + break; + + case 'd': dangles=0; + if (argv[i][2]!='\0') { + r=sscanf(argv[i]+2, "%d", &dangles); + if (r!=1) usage(); + } + break; + case 'P': + if (i==argc-1) usage(); + ParamFile = argv[++i]; + break; + default: usage(); + } + } + + if (ParamFile != NULL) + read_parameter_file(ParamFile); + + if (ns_bases != NULL) { + nonstandards = space(33); + c=ns_bases; + i=sym=0; + if (*c=='-') { + sym=1; c++; + } + while (*c!='\0') { + if (*c!=',') { + nonstandards[i++]=*c++; + nonstandards[i++]=*c; + if ((sym)&&(*c!=*(c-1))) { + nonstandards[i++]=*c; + nonstandards[i++]=*(c-1); + } + } + c++; + } + } + istty = isatty(fileno(stdout))&&isatty(fileno(stdin)); + + do { /* main loop: continue until end of file */ + duplexT mfe, *subopt; + if (istty) { + printf("\nInput two sequences (one line each); @ to quit\n"); + printf("%s\n", scale); + } + fname[0]='\0'; + + if ((line = get_line(stdin))==NULL) break; + /* skip empty lines, comment lines, name lines */ + while (line && ((*line=='*')||(*line=='\0')||(*line=='>'))) { + printf("%s\n", line); free(line); + if ((line = get_line(stdin))==NULL) break; + } + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + s1 = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",s1); free(line); + + if ((line = get_line(stdin))==NULL) break; + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + printf("%s\n", line); free(line); + if ((line = get_line(stdin))==NULL) break; + } + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + s2 = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",s2); free(line); + + + /* get force_binding strings */ + if (!all_pairs) + { + if ((line = get_line(stdin))==NULL) break; + (void) sscanf(line,"%s",tmp_string); free(line); + parse_mapping_array (&array_i, &array_size_i, tmp_string); + + if ((line = get_line(stdin))==NULL) break; + (void) sscanf(line,"%s",tmp_string); free(line); + parse_mapping_array (&array_j, &array_size_j, tmp_string); + } + + for (l = 0; l < strlen(s1); l++) { + s1[l] = toupper(s1[l]); + if (!noconv && s1[l] == 'T') s1[l] = 'U'; + } + for (l = 0; l < strlen(s2); l++) { + s2[l] = toupper(s2[l]); + if (!noconv && s2[l] == 'T') s2[l] = 'U'; + } + if (istty) + printf("lengths = %d,%d\n", strlen(s1), strlen(s2)); + + /* initialize_fold(length); */ + update_fold_params(); + if (delta>=0) { + duplexT *sub; + subopt = duplex_subopt(s1, s2, delta, 0); + for (sub=subopt; sub->i >0; sub++) { + print_struc(sub); + free(sub->structure); + } + free(subopt); + } + else { + mfe = duplexfold(s1, s2); + + /* print_struc(&mfe); */ + + l1 = strchr(mfe.structure, '&') - mfe.structure; + l2 = strlen(mfe.structure) - l1 - 1; + + printf ("%s\t%d\t%d\t%d\t%d\t%d\t%d\t%5.2f\t%5.2f\t%5.2f\n", + mfe.structure, + mfe.i+1-l1, + mfe.i, + mfe.j, + mfe.j+l2-1, + l1, + l2, + mfe.energy, (float) (E5p) / 100., (float) (E3p) / 100.); + + + free(mfe.structure); + } + (void) fflush(stdout); + + (void) fflush(stdout); + free(s1); free(s2); + } while (1); + return 0; +} + +static void print_struc(duplexT const *dup) { + int l1; + l1 = strchr(dup->structure, '&')-dup->structure; + + + printf("%s %3d,%-3d : %3d,%-3d (%5.2f)\n", dup->structure, dup->i+1-l1, + dup->i, dup->j, dup->j+strlen(dup->structure)-l1-2, dup->energy); +} + +static void usage(void) +{ + nrerror("usage:\n" + "RNAduplex [-e range] [-s]\n" + " [-T temp] [-4] [-d] [-noGU] [-noCloseGU]\n" + " [-noLP] [-P paramfile] [-nsp pairs] [-noconv]\n"); +} + +void parse_mapping_array (int **map_array, int *array_size, char *arguments_string) +{ + char *p; + int value; + int cur_array_size = 0; + + if (*map_array) free (*map_array); + + *map_array = (int *) space(sizeof(int) * (50)); + + p = strtok (arguments_string,","); + while (p != NULL) + { + value = atoi (p); + /* printf ("position %i: string=%s, value=%i\n", cur_array_size, p, value); */ + (*map_array)[cur_array_size++] = value; + p = strtok (NULL, ","); + } + + *array_size = cur_array_size; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAduplex.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAduplex.o new file mode 100755 index 0000000000000000000000000000000000000000..026b1f4c545f8af981c5d102e0e978253ff8bfa6 GIT binary patch literal 27576 zcmeHve|%NNweRfg1P&x{g8UE^^aueGgpfeMfGCM1aB_{93Ir7JcsMzMKsZUy4+M)6 zgjkLd4Ag##O11s8Rjl`_@4i=!^ePlYv0huNQh&FiJ};?1z#rFQ{gJoU%vyU-CTHK? zzJK4FPqJsN@2vUGnwd4T_nGr!OLgu1EXxv{EODuDHAaPaVY(|`_LEcm>X>GNi8{e4D3##@soI|P5(zQT`fK+ 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zF2t^4emyHDalBxa3uR@6f4pI+t4_#E2@7VcsMUw-wYV}h3SaQ_+vYSEPveacn~i2v zL% */ +/* + + Calculate Energy of given Sequences and Structures + c Ivo L Hofacker + Vienna RNA Pckage +*/ +#include +#include +#include +#include +#include +#include +#include +#include "fold_vars.h" +#include "fold.h" +#include "utils.h" +#ifdef __GNUC__ +#define UNUSED __attribute__ ((unused)) +#else +#define UNUSED +#endif + +/*@unused@*/ +static char UNUSED rcsid[]="$Id: RNAeval.c,v 1.8 2001/08/23 08:31:13 ivo Exp $"; + +#define PUBLIC +#define PRIVATE static + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +PRIVATE char *costring(char *string); +PRIVATE char *tokenize(char *line); +PRIVATE void usage(void); +extern int logML; +extern int cut_point; +extern int eos_debug; +extern void read_parameter_file(const char fname[]); + +int main(int argc, char *argv[]) +{ + char *line, *string, *structure; + char fname[12]; + char *ParamFile=NULL; + int i, l, length1, length2; + float energy; + int istty; + int noconv=0; + + string=NULL; + for (i=1; i')) { + if (*line=='>') + (void) sscanf(line, ">%s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + + if (line==NULL) break; + if (strcmp(line, "@") == 0) {free(line); break;} + + string = tokenize(line); + free(line); + length2 = (int) strlen(string); + + if ((line = get_line(stdin))==NULL) break; + /* skip comment lines */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + if (line==NULL) break; + if (strcmp(line, "@") == 0) {free(line); break;} + + structure = tokenize(line); + free(line); + length1 = (int) strlen(structure); + + if(length1!=length2) + nrerror("Sequence and Structure have unequal length."); + + for (l = 0; l < length1; l++) { + string[l] = toupper((int)string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + + if (istty) { + if (cut_point == -1) + printf("length = %d\n", length1); + else + printf("length1 = %d\nlength2 = %d\n", + cut_point-1, length1-cut_point+1); + } + + energy = energy_of_struct(string, structure); + if (cut_point == -1) + printf("%s\n%s", string, structure); + else { + char *pstring, *pstruct; + pstring = costring(string); + pstruct = costring(structure); + printf("%s\n%s", pstring, pstruct); + free(pstring); + free(pstruct); + } + if (istty) + printf("\n energy = %6.2f\n", energy); + else + printf(" (%6.2f)\n", energy); + + free(string); + free(structure); + (void) fflush(stdout); + } while (1); + return 0; +} + +PRIVATE char *tokenize(char *line) +{ + char *token, *copy, *ctmp; + int cut = -1; + + copy = (char *) space(strlen(line)+1); + ctmp = (char *) space(strlen(line)+1); + (void) sscanf(line, "%s", copy); + ctmp[0] = '\0'; + token = strtok(copy, "&"); + cut = strlen(token)+1; + while (token) { + strcat(ctmp, token); + token = strtok(NULL, "&"); + } + if (cut > strlen(ctmp)) cut = -1; + if (cut > -1) { + if (cut_point==-1) cut_point = cut; + else if (cut_point != cut) { + fprintf(stderr,"cut_point = %d cut = %d\n", cut_point, cut); + nrerror("Sequence and Structure have different cut points."); + } + } + free(copy); + + return ctmp; +} + +PRIVATE char *costring(char *string) +{ + char *ctmp; + int len; + + len = strlen(string); + ctmp = (char *)space((len+2) * sizeof(char)); + /* first sequence */ + (void) strncpy(ctmp, string, cut_point-1); + /* spacer */ + ctmp[cut_point-1] = '&'; + /* second sequence */ + (void) strcat(ctmp, string+cut_point-1); + + return ctmp; +} + +PRIVATE void usage(void) +{ + nrerror("usage: RNAeval [-T temp] [-4] [-d[0|1|2]] [-e e_set] [-logML] [-P paramfile]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAeval.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAeval.o new file mode 100755 index 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      V}giByKWK(wh^-;NgUwRDP-uAI}SY)De(Q$y^;Q<#*b!@Dv89qH2C=t!q~ zeR{#CBbDF;nbXiRmm9LWyU>taoZiu)j-~0t&Yv=?&^%6W>2NHim8YG#xM9(PQ%zH0 zmdn%BKuKdKSm|<;OwC_TN#gU!L>#lmU$Dea=X0^rz}O*b#n_Zj2_0a5=B($*iKogq zO?)(6`gA-Qmqt+rb6$4Sz@qqLy5mOWGRaspS8By3EFYxt9vUN;{LXC3@1c2~tXjcz zf2km;mU)pDFiuF)K}nLy&_F|v$Fh0rmEq|n$VBZh?OKzG=YmpIT|C=5ST;wiOQw`h zMy8+Y!mu}X(ICS(Ky4sj$*oc`8sGE^76qgfrdHAHS&H$jXWxLbUKRo((bv4^rrI&< z_w`errZQxbIy!4}nMOr4mdcjubv^gfInFi-AgR-F)Y?cDN=}<+9QT+Tc1$F8gpmfU zQzX@urku!imD;rnpAN)%zFi%Ow>Ri5Q{3H~plOX}<($t0sEb13G{UZwGCNRjCOeOv zU22TSNhv}KJJWtTLqoY+#$~#&BrR%a^A|5zykLo45@>DX6`7o)yid>@W~G{B`miH~ z9CHrZRO(*%LggLI zR+Fhxe@o^98sEHQE$^G6L2AcGYi|(E@ym>8iTm9CCIZbovY=+kn-=}GqQkt|!`P`t? zrT6norG6$)iv*o`6vnn)WRbtclR#ldD(iSr>ibbs9%gI^d|s1TXQ}mMswtHW68+7z zo#Q2|s0)zx?mUbhi}Dt@E0uPqe@+KFktwwjw;NSnqwU(_=d+aFlyUZ)Lzg~I?HSyG zec60R+(gSdPg0Z^XoQ#Qr~aXT4i@J#MR$22`>DK>RkTnS22+x^jMVGVOedf8uuF}` zU%1*|M%%b7d3 */ +/* + Ineractive Access to folding Routines + + c Ivo L Hofacker + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "part_func.h" +#include "fold_vars.h" +#include "PS_dot.h" +#include "utils.h" +extern void read_parameter_file(const char fname[]); +extern float circfold(const char *string, char *structure); +/*@unused@*/ +static char rcsid[] = "$Id: RNAfold.c,v 1.18 2005/10/30 20:07:12 ivo Exp $"; + +#define PRIVATE static + +static char scale1[] = "....,....1....,....2....,....3....,....4"; +static char scale2[] = "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *string, *line; + char *structure=NULL, *cstruc=NULL; + char fname[13], ffname[20], gfname[20]; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + int i, length, l, sym, r; + double energy, min_en; + double kT, sfact=1.07; + int pf=0, istty; + int noconv=0; + int circ=0; + + do_backtrack = 1; + string=NULL; + for (i=1; i : base i is paired with a base j>i\n"); + printf("matching brackets ( ): base i pairs base j\n"); + } + + do { /* main loop: continue until end of file */ + if (istty) { + printf("\nInput string (upper or lower case); @ to quit\n"); + printf("%s%s\n", scale1, scale2); + } + fname[0]='\0'; + if ((line = get_line(stdin))==NULL) break; + + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + if (*line=='>') + (void) sscanf(line, ">%12s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + string = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",string); + free(line); + length = (int) strlen(string); + + structure = (char *) space((unsigned) length+1); + if (fold_constrained) { + cstruc = get_line(stdin); + if (cstruc!=NULL) + strncpy(structure, cstruc, length); + else + fprintf(stderr, "constraints missing\n"); + } + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + if (istty) + printf("length = %d\n", length); + + /* initialize_fold(length); */ + if (circ) + min_en = circfold(string, structure); + else + min_en = fold(string, structure); + printf("%s\n%s", string, structure); + if (istty) + printf("\n minimum free energy = %6.2f kcal/mol\n", min_en); + else + printf(" (%6.2f)\n", min_en); + + (void) fflush(stdout); + + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_ss.ps"); + strcpy(gfname, fname); + strcat(gfname, "_ss.g"); + } else { + strcpy(ffname, "rna.ps"); + strcpy(gfname, "rna.g"); + } + if (length<2000) + (void) PS_rna_plot(string, structure, ffname); + else { + struct bond *bp; + fprintf(stderr,"INFO: structure too long, not doing xy_plot\n"); + + /* free mfe arrays but preserve base_pair for PS_dot_plot */ + bp = base_pair; base_pair = space(16); + free_arrays(); /* free's base_pair */ + base_pair = bp; + } + if (pf) { + if (circ) + nrerror("Currently no partition function for circular RNAs. Please implement it!"); + if (dangles==1) { + dangles=2; /* recompute with dangles as in pf_fold() */ + min_en = energy_of_struct(string, structure); + dangles=1; + } + + kT = (temperature+273.15)*1.98717/1000.; /* in Kcal */ + pf_scale = exp(-(sfact*min_en)/kT/length); + if (length>2000) fprintf(stderr, "scaling factor %f\n", pf_scale); + + init_pf_fold(length); + + if (cstruc!=NULL) + strncpy(structure, cstruc, length+1); + energy = pf_fold(string, structure); + + if (do_backtrack) { + printf("%s", structure); + if (!istty) printf(" [%6.2f]\n", energy); + else printf("\n"); + } + if ((istty)||(!do_backtrack)) + printf(" free energy of ensemble = %6.2f kcal/mol\n", energy); + printf(" frequency of mfe structure in ensemble %g; ", + exp((energy-min_en)/kT)); + if (do_backtrack) { + printf("ensemble diversity %-6.2f", mean_bp_dist(length)); + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp.ps"); + } else strcpy(ffname, "dot.ps"); + (void) PS_dot_plot(string, ffname); + } + printf("\n"); + free_pf_arrays(); + + } + if (cstruc!=NULL) free(cstruc); + if (length>=2000) free(base_pair); + (void) fflush(stdout); + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE void usage(void) +{ + nrerror("usage:\n" + "RNAfold [-p[0]] [-C] [-T temp] [-4] [-d[2|3]] [-noGU] [-noCloseGU]\n" + " [-noLP] [-e e_set] [-P paramfile] [-nsp pairs] [-S scale]\n" + " [-noconv] [-circ] \n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAfold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAfold.o new file mode 100755 index 0000000000000000000000000000000000000000..22fadda5d179470f129d0728477bc5fcd93e4f47 GIT binary patch literal 26944 zcmeHve|%KcweOysfJ2Cx00B{{4w5J+1>Ctlw_swi?4}ikRHHG zG`b!BRb3s}cV_noSMEFG(@Sc~2CEus%1%_(*OYx!wRCaMAM1PmyY5L;AGqPeyWuwX zuZKopTM6}47nUEYE}Vn_+$Yk#0Ph=49+(6|(d~l==6>+4l}o~}UD}&{q^o>J$H%^> zD?K;$&%Wu4dF$r%^bHn1hw@mfR3q2bnI+QC1-5o(J%Mal-_v;O$IIaJ>4*C-7=!|f 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+#define PRIVATE static +#define PUBLIC +#define MAXWIDTH 201 +/*@unused@*/ +static char rcsid[] = "$Id: RNAheat.c,v 1.12 2000/09/28 11:23:14 ivo Rel $"; + +PRIVATE float F[MAXWIDTH]; +PRIVATE float ddiff(float f[], float h, int m); +PRIVATE void usage(void); + +#define GASCONST 1.98717 /* in [cal/K] */ +#define K0 273.15 + +PRIVATE void heat_capacity(char *string, float T_min, float T_max, + float h, int m) +{ + int length, i; + char *structure; + float hc, kT, min_en; + + length = (int) strlen(string); + + do_backtrack = 0; + + temperature = T_min -m*h; + initialize_fold(length); + structure = (char *) space((unsigned) length+1); + min_en = fold(string, structure); + free(structure); free_arrays(); + kT = (temperature+K0)*GASCONST/1000; /* in kcal */ + pf_scale = exp(-(1.07*min_en)/kT/length ); + init_pf_fold(length); + + for (i=0; i<2*m+1; i++) { + F[i] = pf_fold(string, NULL); /* T_min -2h */ + temperature += h; + kT = (temperature+K0)*GASCONST/1000; + pf_scale=exp(-(F[i]/length +h*0.00727)/kT); /* try to extrapolate F */ + update_pf_params(length); + } + while (temperature <= (T_max+m*h+h)) { + + hc = - ddiff(F,h,m)* (temperature +K0 - m*h -h); + printf("%g %g\n", (temperature-m*h-h), hc); + + for (i=0; i<2*m; i++) + F[i] = F[i+1]; + F[2*m] = pf_fold(string, NULL); + temperature += h; + kT = (temperature+K0)*GASCONST/1000; + pf_scale=exp(-(F[i]/length +h*0.00727)/kT); + update_pf_params(length); + } + free_pf_arrays(); +} + +/* ------------------------------------------------------------------------- */ + +PRIVATE float ddiff(float f[], float h, int m) +{ + float fp; + int i; + float A, B; + A = (float)(m*(m+1)*(2*m+1)/3 ); /* 2*sum(x^2) */ + B = (float)(m*(m+1)*(2*m+1) ) * (float)(3*m*m+3*m-1) /15.; /* 2*sum(x^4) */ + + fp=0.; + for (i=0; i<2*m+1; i++) + fp += f[i]*( A - (float) ( (2*m+1)*(i-m)*(i-m)) ); + + fp /= ( ( A*A - B*( (float)(2*m+1) ) )*h*h/2. ); + return (float)fp; + +} + +/* ------------------------------------------------------------------------- */ + +static char scale1[] = "....,....1....,....2....,....3....,....4"; +static char scale2[] = "....,....5....,....6....,....7....,....8"; + +/*---------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *string, *line; + char *ns_bases=NULL, *c; + char *ParamFile=NULL; + int i, length, l, sym; + float T_min, T_max, h; + int mpoints; + int istty; + int noconv = 0; + + T_min=0.; T_max=100.; h=1; mpoints=2; + string=NULL; + dangles = 2; /* dangles can be 0 (no dangles) or 2, default is 2 */ + + for (i=1; i100) mpoints=100; + break; + case 'd': dangles=0; + break; + case 'P': + if (i==argc-1) usage(); + else + ParamFile= argv[++i]; + break; + default: usage(); + } + } + + if (ParamFile!=NULL) + read_parameter_file(ParamFile); + + if (ns_bases!=NULL) { + nonstandards = space(33); + c=ns_bases; + i=sym=0; + if (*c=='-') { + sym=1; c++; + } + while (*c!='\0') { + if (*c!=',') { + nonstandards[i++]=*c++; + nonstandards[i++]=*c; + if ((sym)&&(*c!=*(c-1))) { + nonstandards[i++]=*c; + nonstandards[i++]=*(c-1); + } + } + c++; + } + } + + istty = isatty(fileno(stdout))&&isatty(fileno(stdin)); + + do { + if (istty) { + printf("\nInput string (upper or lower case); @ to quit\n"); + printf("%s%s\n", scale1, scale2); + } + + if ((line = get_line(stdin))==NULL) break; + + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + if (line==NULL) break; + if (strcmp(line, "@") == 0) {free(line); break;} + + string = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",string); + free(line); + length = (int) strlen(string); + + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + + if (istty) + printf("length = %d\n", length); + + heat_capacity(string, T_min, T_max, h, mpoints); + free(string); + (void) fflush(stdout); + } while (1); + return 0; +} + +PRIVATE void usage(void) +{ + nrerror("usage: RNAheat [-Tmin t1] [-Tmax t2] [-h stepsize] [-m ipoints] [-4] [-d]\n" + " [-noGU] [-noCloseGU] [-noLP] [-e 1|2] [-P paramfile] [-nsp pairs]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAheat.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAheat.o new file mode 100755 index 0000000000000000000000000000000000000000..399ead99ae9e870943eac521272515992b648136 GIT binary patch literal 24808 zcmeHve{@vUwg0)f0R|G7@IwVb93)`)kslKgLqJGifJCE4Lc)&%!!VhUDPc0sO!(2N zL;)oa16XZKTl^N=F6DLk)V4mr)@nc#QD0lM`ik}0XSG()zFMKBQh(&_ea_x@PEO{o zzW3H!-#@ z2I(_+X=>UB|0**VI_NF{F9lfVf#|=Brdw2W;5YJ42i~m0)=NK(Dv=B-PfXLFsKTwrAHml%W7wrcV{PzB(NJA7a}(V{Gbj}qH1SXRmZd59V4W} zp7skByTK)(ILT#p6Jq z^X9?q1$MXO2Y{@}uL1FM-r<4#GTBlEbWQ#YiIhk+-eoUzJYU`M9L(`_l>%t~T%~vF 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z$#kf5SXV4;sIDlg?Ia>oydFNH1LHwE)c7P<%oK}~8i-!HG-#|;dTeHjDU(<|>x61-TXO5*yQ=TSWbwPuye z)A=%*`%(ik3eCEj*INr27@SXr&{64mG(K8eE?;d&)iAa*ds{KV+&Yj+ zmGmqf1oHS2{5Y7)t_@@g(6gnU2RJ4IQ>S94Fb1b(b0mwbJg?NPhkLru8)9Pq>{)^M zML#8l7Q8svv5h%T^3G22VpCc#Zb3OeSddXKsZzO%T&kNkdU^1Sg``D`Y zPkK(1#m%2I^x7z^d{)*$y>YJWj9!U!isoevu@iJ@q__te^Q2j@V9}DfO^bphXP&uq zerwR$GLzmeMfqH&e?!7-P^vP%7ESCtSirsn# zt($6A!CC8qWTsb=CsRD5KUFG8XqmKKe!BYUW!<6kEi2~)pS6p */ +#include +#include +#include +#include +#include +#include +#include "inverse.h" +#include "fold_vars.h" +#include "fold.h" +#include "part_func.h" +#include "utils.h" +#ifdef dmalloc +#include "/usr/local/include/dmalloc.h" +#define space(X) calloc(1,(X)) +#endif + +#define PUBLIC +#define PRIVATE static +/*@unused@*/ +static char rcsid[] = "$Id: RNAinverse.c,v 1.11 2000/09/28 12:59:21 ivo Rel $"; +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +#define REPEAT_DEFAULT 100 +#define INFINITY 100000 + +extern void read_parameter_file(const char fname[]); + +PRIVATE void usage(void); +extern int inv_verbose; + +int main(int argc, char *argv[]) +{ + char *start, *structure, *rstart, *str2, *line; + char *ParamFile=NULL; + int i,j, length, l, hd; + double energy=0., kT; + int pf, mfe, istty; + int repeat, found; + + do_backtrack = 0; pf = 0; mfe = 1; + repeat = 0; + init_rand(); + for (i=1; i')) { + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + /* stop at eof or '@' */ + if (line==NULL) break; + if (strcmp(line, "@") == 0) {free(line); break;} + + structure = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",structure); /* scanf gets rid of trailing junk */ + free(line); + + length = (int) strlen(structure); + str2 = (char *) space((unsigned)length+1); + + if ((line = get_line(stdin))!=NULL) + if (strcmp(line, "@") == 0) {free(line); break;} + + start = (char *) space((unsigned) length+1); + if (line !=NULL) { + (void) strncpy(start, line, length); + free(line); + } + + if (istty) printf("length = %d\n", length); + + if (repeat!=0) found = (repeat>0)? repeat : (-repeat); + else found = 1; + + initialize_fold(length); + + rstart = (char *) space((unsigned)length+1); + while(found>0) { + char *string; + string = (char *) space((unsigned)length+1); + strcpy(string, start); + for (i=0; i=0) || (energy<=0.0) ) { + found--; + hd = hamming(rstart, string); + printf("%s %3d", string, hd); + if (energy>0) { /* no solution found */ + printf(" d= %g\n", energy); + if(istty) { + energy = fold(string,str2); + printf("%s\n", str2); + } + } else printf("\n"); + } + } + if (pf) { + if (!(mfe && give_up && (energy>0))) { + /* unless we gave up in the mfe part */ + double prob, min_en, sfact=1.07; + + /* get a reasonable pf_scale */ + min_en = fold(string,str2); + pf_scale = exp(-(sfact*min_en)/kT/length); + init_pf_fold(length); + + energy = inverse_pf_fold(string, structure); + prob = exp(-energy/kT); + hd = hamming(rstart, string); + printf("%s %3d (%g)\n", string, hd, prob); + free_pf_arrays(); + } + if (!mfe) found--; + } + (void) fflush(stdout); + free(string); + } + free(rstart); + free_arrays(); + + free(structure); + free(str2); + free(start); + (void) fflush(stdout); + } while (1); + return 0; +} + + +PRIVATE void usage(void) +{ + nrerror("usage: RNAinverse [-F[mp]] [-a ALPHABET] [-R [repeats]] [-f final]\n" + " [-T temp] [-4] [-d[2]] [-noGU] [-P paramfile] [-e e_set] [-v]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAinverse.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAinverse.o new file mode 100755 index 0000000000000000000000000000000000000000..82a01b113041603e29e1850a32d891e81a5fa31e GIT binary patch literal 22160 zcmeI4dw5jUwZQkuNnnJS2@nv)%25IaAunDA5Y0e8v|4NR`f6`0skKFHDONCdt-aSev$Hej)_(W? z+5O3!y?%S`wbp)~bM{Q!G<)8h9Lo}%EOE8SNKAz|IXaWCmf33Ih|h?pG2e|JO-;Mu zzrd1T{vpuW6R4~0JRMjZShV;lw6-v~<@ZaE<)Ip;;IW$G63o1@yx4(!5$54qh`MlH 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+#include +#include +#include +#include +#include +#include "dist_vars.h" +#include "RNAstruct.h" +#include "treedist.h" +#include "stringdist.h" +#include "utils.h" + + +#define MAXNUM 1000 /* max number of structs for distance matrix */ +#define PRIVATE static +#define PUBLIC + + + +PRIVATE void usage(void); +PRIVATE int parse_input(char *line); + + + +PRIVATE int types = 1; /* number of distance types */ +PRIVATE char ttype[10] = "f"; /* distance types */ +PRIVATE int n = 0; /* number of structures read so far */ + + +int main(int argc, char *argv[]) +{ + int tree_types = 0, ttree; + int string_types = 0, tstr; + char *line=NULL, *xstruc, *cc; + int i, j, tt, type; + int it, is; + float dist; + int comp_to_first = 0; + int max = MAXNUM; + + + edit_backtrack = 0; + + /* reading parameters */ + for (i = 1; i < argc; i++) { + if (argv[i][0] == '-') { + if (argv[i][1] == 'D') { + strncpy(ttype, argv[i]+2, 9); + types = (int)strlen(ttype); + } + else if (argv[i][1] == 'F') + comp_to_first = 1; + else if (argv[i][1] == 'M') { + max = atoi(argv[i+1]) + 10; + i++; + } + else + usage(); + } + else + usage(); + } + + Tree *T[5][max]; + swString *S[5][max]; + char *P[max]; /* structures for base pair distances */ + + /* reading sequences from stdin and calculating distances */ + line = get_line(stdin); + type = parse_input(line); + while (type != 999) { + + while (type == 0) { + if (line != NULL) + free(line); + + line = get_line(stdin); + type = parse_input(line); + } + + tree_types = 0; + string_types = 0; + for(tt = 0; tt < types; tt++) { + + switch(ttype[tt]){ + case 'f' : + case 'F' : + xstruc = expand_Full(line); + if(islower(ttype[tt])) /* tree_edit */ + T[tree_types++][n] = make_tree(xstruc); + if(isupper(ttype[tt])) /* string edit */ + S[string_types++][n] = Make_swString(xstruc); + free(xstruc); + break; + + case 'P': + P[n] = strdup(line); + break; + + case 'h' : + case 'H' : + xstruc = b2HIT(line); + if(islower(ttype[tt])) + T[tree_types++][n] = make_tree(xstruc); + if(isupper(ttype[tt])) + S[string_types++][n] = Make_swString(xstruc); + free(xstruc); + break; + + case 'c' : + case 'C' : + cc = b2C(line); + xstruc = expand_Shapiro(cc); + free(cc); + if(islower(ttype[tt])) + T[tree_types++][n] = make_tree(xstruc); + if(isupper(ttype[tt])) + S[string_types++][n] = Make_swString(xstruc); + free(xstruc); + break; + + case 'w' : + case 'W' : + xstruc = b2Shapiro(line); + if(islower(ttype[tt])) + T[tree_types++][n] = make_tree(xstruc); + if(isupper(ttype[tt])) + S[string_types++][n] = Make_swString(xstruc); + free(xstruc); + break; + + default: + nrerror("Unknown distance type"); + } + } + n++; + + if (n >= 2) { + it = 0; + is = 0; + if (comp_to_first) { + for (i=0; i < types; i++) { + if(islower(ttype[i])) { + dist = tree_edit_distance(T[it][0], T[it][1]); + free_tree(T[it][1]); + it++; + } + else if (ttype[i]=='P') { + dist = (float)bp_distance(P[0], P[1]); + free(P[1]); + } + else /* isupper(ttype[i]) */ { + dist = string_edit_distance(S[is][0], S[is][1]); + free(S[is][1]); + is++; + } + printf("%c: %g \n", ttype[i], dist); + } + n = 1; + } + else { + for (i=0; i < types; i++) { + if(islower(ttype[i])) { + dist = tree_edit_distance(T[it][0], T[it][1]); + free_tree(T[it][0]); + free_tree(T[it][1]); + it++; + } + else if (ttype[i]=='P') { + dist = (float)bp_distance(P[0], P[1]); + free(P[0]); + free(P[1]); + } + else /* isupper(ttype[i]) */ { + dist = string_edit_distance(S[is][0], S[is][1]); + free(S[is][0]); + free(S[is][1]); + is++; + } + printf("%c: %g \n", ttype[i], dist); + } + n = 0; + } + } + fflush(stdout); + + free(line); + line = get_line(stdin); + type = parse_input(line); + } + + if (comp_to_first) { + it = 0; + is = 0; + for (i=0; i < types; i++) { + if(islower(ttype[i])) + free_tree(T[it++][0]); + else if (ttype[i]=='P') + free(P[0]); + else /* isupper(ttype[i]) */ + free(S[is++][1]); + } + } + + return 0; +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE int parse_input(char *line) +{ + int i,o; + + if (line == NULL) + return 999; + + i=o=0; + while( line[i] ){ + switch(line[i]) { + case '(' : + o++; + i++; + break; + case '.' : + i++; + break; + case ')' : + i++; + o--; + if(o<0) return 0; + break; + default: + return 0; + } + } + if (o>0) + return 0; + return 1; +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void usage(void) +{ + nrerror("usage: RNAmotif_distance [-D[fhwcFHWCP]] [-F] [-M ]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAmotif_distance.c~ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAmotif_distance.c~ new file mode 100755 index 00000000..40022eb9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAmotif_distance.c~ @@ -0,0 +1,548 @@ +/* + Distances of Secondary Structures + Walter Fontana, Ivo L Hofacker, Peter F Stadler + Vienna RNA Package +*/ +#include +#include +#include +#include +#include +#include +#include "dist_vars.h" +#include "RNAstruct.h" +#include "treedist.h" +#include "stringdist.h" +#include "utils.h" + +#define MAXNUM 1000 /* max number of structs for distance matrix */ + +#define PUBLIC +#define PRIVATE static +/*@unused@*/ +static char rcsid[] = "$Id: RNAdistance.c,v 1.8 2005/07/24 08:35:15 ivo Exp $"; +PRIVATE void command_line(int argc, char *argv[]); +PRIVATE void usage(void); +PRIVATE int parse_input(char *line); +PRIVATE int check_tree(char *line, char alpha[]); +PRIVATE int check_brackets(char *line); +PRIVATE void print_aligned_lines(FILE *somewhere); + +PRIVATE char ruler[] ="....,....1....,....2....,....3....,....4" +"....,....5....,....6....,....7....,....8"; +PRIVATE int types=1; +PRIVATE int task; +PRIVATE int taxa_list; +PRIVATE char outfile[50], *list_title; + +PRIVATE char ttype[10]="f"; +PRIVATE int n=0; + +int main(int argc, char *argv[]) +{ + char *line=NULL, *xstruc, *cc; + Tree *T[10][MAXNUM]; + int tree_types = 0, ttree; + swString *S[10][MAXNUM]; + char *P[MAXNUM]; /* structures for base pair distances */ + int string_types = 0, tstr; + int i,j, tt, istty, type; + int it, is; + FILE *somewhere=NULL; + + command_line(argc, argv); + + if((outfile[0]=='\0')&&(task==2)&&(edit_backtrack)) + strcpy(outfile,"backtrack.file"); + if(outfile[0]!='\0') somewhere = fopen(outfile,"w"); + if (somewhere==NULL) somewhere = stdout; + istty = isatty(fileno(stdin))&&isatty(fileno(stdout)); + + do { + if ((istty)&&(n==0)) { + printf("\nInput structure; @ to quit\n"); + printf("%s\n", ruler); + } + do { + if (line!=NULL) free(line); + line=get_line(stdin); + } while ((type=parse_input(line))==0); + + if (((type==999)||(type==888))&&(task==2)) { /* do matrices */ + if (taxa_list) + printf("* END of taxa list\n"); + + ttree = 0; tstr = 0; + for (tt=0; tt< types; tt++) { + printf("> %c %d\n", ttype[tt], n); + if(islower(ttype[tt])) { + for (i=1; i1) { + for (it=0, is=0, i=0; i1) { + for (it=0, is=0, i=0; i') { + if (taxa_list) + printf("%d :%s\n", n+1, line+1); + else printf("%s\n", line); + return 0; + } + + cp = strchr(line,' '); + if (cp) *cp='\0'; /* get rid of junk at the end of line */ + + switch (line[0]) { + case '.' : + type = 1; + break; + + case '(' : /* it's a tree */ + i=1; + xx = 0; + type = 4; /* coarse */ + rooted = 0; + while (line[i]) { + if (line[i]=='.'){ + type = 1; /* Full */ + break; + } + if ( (line[i]=='U')||(line[i]=='P') ) { + type = 2; /* FFull */ + xx = 1; + break; + } + if (line[i]=='S') { + type = 3; + xx = 1; + break; /* Shapiro tree */ + } + if ((line[i]!='(')&&(line[i]!=')')) xx = 1; + i++; + } + if(!xx) type =1; + + rooted = (line[strlen(line)-2]=='R'); + break; + case '@' : + return 999; + + default: + return 0; + } + + switch (type) { + case 1: + if(check_brackets(line)) + return 1; + break; + case 2: + if(check_tree(line,"UP") ) { + if(rooted) return 2; + else return -2; + } + break; + case 3: + if(check_tree(line,"HBIMSE") ){ + if(rooted) return -3; + else return -3; + } + break; + case 4: + if(check_tree(line,"HBIM") ){ + if(rooted) return 4; + else return -4; + } + break; + } + return 0; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE int check_tree(char *line, char alpha[]) +{ + int n, i, o; + char *pos; + + n = (int) strlen(line); + + if( line[0] != '(' ) return 0; + i=o=1; + while( line[i] ){ + while( line[i] == '(' ){ + o++; + i++; + } + pos=strchr(alpha, (int)line[i]); + if (pos) { + while (isdigit((int) line[++i])); + if (line[i]!=')') return 0; + } + if (line[i]=='R') { + i++; + if ((i!=n-1)||(line[i]!=')')) return 0; + } + if (line[i]==')') { + o--; + if(o< 0) return 0; + if( (i0) return 0; + return 1; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE int check_brackets(char *line) +{ + int i,o; + + i=o=0; + while( line[i] ){ + switch(line[i]) { + case '(' : + o++; + i++; + break; + case '.' : + i++; + break; + case ')' : + i++; + o--; + if(o<0) return 0; + break; + default: + return 0; + } + } + if (o>0) return 0; + return 1; +} + +/*--------------------------------------------------------------------------*/ + + +PRIVATE void command_line(int argc, char *argv[]) +{ + int i; + + edit_backtrack = 0; + types=1; ttype[0]='f'; task=1; + + for (i=1; i= argc) outfile[0] = '\0'; + else if (argv[i+1][0]=='-') outfile[0] = '\0'; + else { + i++; + strncpy(outfile,argv[i],49); + } + edit_backtrack = 1; + break; + default: + usage(); + } + } +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void print_aligned_lines(FILE *somewhere) +{ + if (edit_backtrack) { + fprintf(somewhere, "\n%s\n%s\n", aligned_line[0], aligned_line[1]); + fflush(somewhere); + } +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void usage(void) +{ + nrerror("usage: RNAdistance [-D[fhwcFHWCP]] [-X[p|m|f|c]] [-S] [-B [file]]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAmotif_distance.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAmotif_distance.o new file mode 100755 index 0000000000000000000000000000000000000000..aeb26bc48ada9a63ace52ffca57e62b21f1e557f GIT binary patch literal 19216 zcmeI3dw5mVmB9D8C&3GZ+=TFwmsfcR2sea>O#qcZ0yh*i1%gxqm&?t~Ly~*LeL%1X zDFG#o!PNHaFdx-nI*+2ZQ~GtPj9Q9-B44FLEp4efHmf&KETSZ1C7mD#>j0o=O zJ@Sq%L@H2ny5!~d+eB(^$uZy2oYIb~Q&Y2d`a7;pN&9=B>pdQf9B*GxD$>6yIkxBY zj)M13)YtdGe;ro?skcgwoj8I{K|axYy!Z6Bmw~AEAEK{|cu;apu=CgDcb2ayKY9VY zme*8u{;qs=`Lo!2Rp-aSj(=|}FMI7&PPCw8XdjgsiOa?S2n>l=q(Ox$uSF-d-@d{e=~g4?f$S^W^f* z^xduwu`MM1&m|7I$2ovvqpsvEGT# zBdF@ye#ZOsAgIA)egMOV|D?l;?$$vUKL8g!az4s?Pf4ttf$i;wx`v~H-s2q~SvwYV ztvD$ocnR5_)2Z2&C2yCPo!nlbW&X})* z^ny}QdFb5J3e$5b+Wuj+Z}*d6wkq;^u&eSQ1Q_&vXWijo*MjrGuGD$2Qtzrc_`a{O 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zX&u~mkJyxb567jMBGn`F)8U2MtY%|b3Iu0G3PsO?Zf|+EX6DNhZ;2MOYML^sSWY>e z=Fli>k@apd0%8}T*K1ruT}+J=9i4;SA5=(e7_;G2VJ9%lI$lI9(o#C3)cjng$L#&- zw0tiZQ_KdOW(mvoGih+d#E+pI znJ()rsOxP#nciNnm>Mx}{YVr$%%)+sJPBo2cP>uccw37rd~R`@mn?a!U8=O`S3$J?rqps}4)0Q&XnSI81K(%uba~OF@@qAl5VHUTCmO$C)pUr_EhgB==`| zxob8O?D6@9!=1qG`66$*q%%<%W*k(~=2T!dr@_5HK8H+VCqn zW-LCWG@FCsV1p(d3<*%lwVO|^=5sdQhD!q%nfQTnKb>7*Pld*tYF zXnUr|oMO428vT{zr?QQs$?Z0|Ejhs+pQ34f;@#pS%?6$8>`B}6v +#include +#include +#include +#include +#include +#include +#include "part_func.h" +#include "fold.h" +#include "fold_vars.h" +#include "profiledist.h" +#include "dist_vars.h" +#include "utils.h" +#include "ProfileAln.h" + +#define PUBLIC +#define PRIVATE static + +#define MAXLENGTH 10000 +#define MAXSEQ 1000 +/*@unused@*/ +static char rcsid[] = "$Id: RNApaln.c,v 1.3 2005/07/24 08:35:15 ivo Exp $"; + +static double gapo=1.5, gape=0.666, seqw=0.5; +static int endgaps=0; + +PRIVATE void command_line(int argc, char *argv[]); +PRIVATE void usage(void); +PRIVATE void print_aligned_lines(FILE *somewhere); + +PRIVATE char task; +PRIVATE char outfile[50]; +PRIVATE char ruler[] ="....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +extern void PS_dot_plot(char *string, char *file); +extern void read_parameter_file(const char fname[]); +extern float profile_aln(const float *T1, const char *seq1, + const float *T2, const char *seq2); +static int noconv = 0; + +int main(int argc, char *argv[]) + +{ + float *T[MAXSEQ]; + char *seq[MAXSEQ]; + int i,j, istty, n=0; + int type, length, taxa_list=0; + float dist; + FILE *somewhere=NULL; + char *structure; + char *line=NULL, fname[20], *list_title=NULL; + + command_line(argc, argv); + + if((outfile[0]=='\0')&&(task=='m')&&(edit_backtrack)) + strcpy(outfile,"backtrack.file"); + if (outfile[0]!='\0') somewhere = fopen(outfile,"w"); + if (somewhere==NULL) somewhere = stdout; + istty = (isatty(fileno(stdout))&&isatty(fileno(stdin))); + + while (1) { + if ((istty)&&(n==0)) { + printf("\nInput sequence; @ to quit\n"); + printf("%s\n", ruler); + } + + type = 0; + do { /* get sequence to fold */ + if (line!=NULL) free(line); + *fname='\0'; + if ((line=get_line(stdin))==NULL) {type = 999; break;} + if (line[0]=='@') type = 999; + if (line[0]=='*') { + if (taxa_list==0) { + if (task=='m') taxa_list=1; + printf("%s\n", line); + type = 0; + } else { + list_title = strdup(line); + type = 888; + } + } + if (line[0]=='>') { + if (sscanf(line,">%12s", fname)!=0) + strcat(fname, "_dp.ps"); + if (taxa_list) + printf("%d : %s\n", n+1, line+1); + else printf("%s\n",line); + type = 0; + } + if (isalpha(line[0])) { + char *cp; + cp =strchr(line,' '); + if (cp) *cp='\0'; + type = 1; + } + } while(type==0); + + if( (task == 'm')&&(type>800) ) { + if (taxa_list) + printf("* END of taxa list\n"); + printf("> p %d (pdist)\n",n); + for (i=1; i %d %d\n",i+1,j+1); + print_aligned_lines(somewhere); + } + printf("\n"); + } + if (type==888) { /* do another distance matrix */ + n = 0; + printf("%s\n", list_title); + free(list_title); + } + } + + if(type>800) { + for (i=0; i1) { + dist = profile_aln(T[1], seq[1], T[0], seq[0]); + printf("%g\n",dist); + print_aligned_lines(somewhere); + free_profile(T[1]); free(seq[1]); + n=1; + } + break; + case 'c' : + if (n>1) { + dist = profile_aln(T[1], seq[1], T[0],seq[0]); + printf("%g\n",dist); + print_aligned_lines(somewhere); + free_profile(T[0]); free(seq[0]); + T[0] = T[1]; seq[0] = seq[1]; + n=1; + } + break; + + case 'm' : + break; + + default : + nrerror("This can't happen."); + } /* END switch task */ + (void) fflush(stdout); + } /* END while */ + if (line !=NULL) free(line); + return 0; +} + +/* ----------------------------------------------------------------- */ + +PRIVATE void command_line(int argc, char *argv[]) +{ + + int i, sym; + char *ns_bases=NULL, *c; + char *ParamFile=NULL; + + task = 'p'; + for (i=1; i= argc) outfile[0] = '\0'; + else if (argv[i+1][0]=='-') outfile[0] = '\0'; + 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diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNApdist.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNApdist.c new file mode 100755 index 00000000..39517449 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNApdist.c @@ -0,0 +1,298 @@ +/* + Distances of Secondary Structure Ensembles + Peter F Stadler, Ivo L Hofacker, Sebastian Bonhoeffer + Vienna RNA Package +*/ +#include +#include +#include +#include +#include +#include +#include +#include "part_func.h" +#include "fold_vars.h" +#include "profiledist.h" +#include "dist_vars.h" +#include "utils.h" + +#define PUBLIC +#define PRIVATE static + +#define MAXLENGTH 10000 +#define MAXSEQ 1000 +/*@unused@*/ +static char rcsid[] = "$Id: RNApdist.c,v 1.8 2002/11/07 12:19:41 ivo Exp $"; + +PRIVATE void command_line(int argc, char *argv[]); +PRIVATE void usage(void); +PRIVATE void print_aligned_lines(FILE *somewhere); + +PRIVATE char task; +PRIVATE char outfile[50]; +PRIVATE char ruler[] ="....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +extern void PS_dot_plot(char *string, char *file); +extern void read_parameter_file(const char fname[]); +static int noconv = 0; + +int main(int argc, char *argv[]) + +{ + float *T[MAXSEQ]; + int i,j, istty, n=0; + int type, length, taxa_list=0; + float dist; + FILE *somewhere=NULL; + char *structure; + char *line=NULL, fname[20], *list_title=NULL; + + command_line(argc, argv); + + if((outfile[0]=='\0')&&(task=='m')&&(edit_backtrack)) + strcpy(outfile,"backtrack.file"); + if (outfile[0]!='\0') somewhere = fopen(outfile,"w"); + if (somewhere==NULL) somewhere = stdout; + istty = (isatty(fileno(stdout))&&isatty(fileno(stdin))); + + while (1) { + if ((istty)&&(n==0)) { + printf("\nInput sequence; @ to quit\n"); + printf("%s\n", ruler); + } + + type = 0; + do { /* get sequence to fold */ + if (line!=NULL) free(line); + *fname='\0'; + if ((line=get_line(stdin))==NULL) {type = 999; break;} + if (line[0]=='@') type = 999; + if (line[0]=='*') { + if (taxa_list==0) { + if (task=='m') taxa_list=1; + printf("%s\n", line); + type = 0; + } else { + list_title = strdup(line); + type = 888; + } + } + if (line[0]=='>') { + if (sscanf(line,">%12s", fname)!=0) + strcat(fname, "_dp.ps"); + if (taxa_list) + printf("%d : %s\n", n+1, line+1); + else printf("%s\n",line); + type = 0; + } + if (isalpha(line[0])) { + char *cp; + cp =strchr(line,' '); + if (cp) *cp='\0'; + type = 1; + } + } while(type==0); + + if( (task == 'm')&&(type>800) ) { + if (taxa_list) + printf("* END of taxa list\n"); + printf("> p %d (pdist)\n",n); + for (i=1; i %d %d\n",i+1,j+1); + print_aligned_lines(somewhere); + } + printf("\n"); + } + if (type==888) { /* do another distance matrix */ + n = 0; + printf("%s\n", list_title); + free(list_title); + } + } + + if(type>800) { + for (i=0; i1) { + dist = profile_edit_distance(T[1], T[0]); + printf("%g\n",dist); + print_aligned_lines(somewhere); + free_profile(T[1]); + n=1; + } + break; + case 'c' : + if (n>1) { + dist = profile_edit_distance(T[1], T[0]); + printf("%g\n",dist); + print_aligned_lines(somewhere); + free_profile(T[0]); + T[0] = T[1]; + n=1; + } + break; + + case 'm' : + break; + + default : + nrerror("This can't happen."); + } /* END switch task */ + (void) fflush(stdout); + } /* END while */ + if (line !=NULL) free(line); + return 0; +} + +/* ----------------------------------------------------------------- */ + +PRIVATE void command_line(int argc, char *argv[]) +{ + + int i, sym; + char *ns_bases=NULL, *c; + char *ParamFile=NULL; + + task = 'p'; + for (i=1; i= argc) outfile[0] = '\0'; + else if (argv[i+1][0]=='-') outfile[0] = '\0'; + else { + i++; + strncpy(outfile,argv[i],49); + } + edit_backtrack = 1; + break; + case 'P': + if (++iRf&45_rq4Jr(zYJ8H z@BVSW`4MQN%H3qYzc=7l2VFrcp?--IAU%sx=pDwSd^nY4jUEcXc`P!A8 z|5^Prv|vr(ra$bREX2YudSx52XDf=vVQt7qV;%s)qloMx%y;GYeF9nfc*Vj$-f(3g 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAplfold.c new file mode 100755 index 00000000..6bfae6cb --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAplfold.c @@ -0,0 +1,214 @@ +/* Last changed Time-stamp: <2006-01-16 10:38:56 ivo> */ +/* + Ineractive Access to folding Routines + + c Ivo L Hofacker + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "part_func.h" +#include "fold_vars.h" +#include "utils.h" +#include "PS_dot.h" + +extern float Lfold(char *string, char *structure, int maxdist); +extern void read_parameter_file(const char fname[]); +extern int pfl_fold(char *sequence, int winSize, float cutoff, struct plist **pl); +extern void init_pf_foldLP(int length); +extern void free_pf_arraysLP(void); + +/*@unused@*/ +static char rcsid[] = "$Id: RNAplfold.c,v 1.2 2006/01/16 09:49:07 ivo Exp $"; + +#define PRIVATE static + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *string, *line; + char *structure=NULL, *cstruc=NULL; + char fname[30], ffname[20]; + char *ParamFile=NULL; + char *ns_bases=NULL, *c; + int i, length, l, sym,r; + int istty; + int noconv=0; + int maxdist=70; + int winSize; + float cutoff=0.01; + int hit; + plist *pl; + do_backtrack = 1; + string=NULL; + dangles=2; + for (i=1; i')) { + if (*line=='>') + (void) sscanf(line, ">%12s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) break; + } + + if ((line ==NULL) || (strcmp(line, "@") == 0)) break; + + string = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",string); + free(line); + length = (int) strlen(string); + + structure = (char *) space((unsigned) length+1); + + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') string[l] = 'U'; + } + if (istty) + printf("length = %d\n", length); + + /* initialize_fold(length); */ + update_fold_params(); + maxdist=winSize; + if (length= 5) { + pf_scale = -1; + + init_pf_foldLP(length); + + hit=pfl_fold(string, maxdist, cutoff, &pl); + free_pf_arraysLP(); + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_dp.ps"); + } + else strcpy(ffname, "plfold_dp.ps"); + PS_dot_plot_turn(string, pl, ffname, maxdist); + free(pl); + + if (cstruc!=NULL) free(cstruc); + (void) fflush(stdout); + } + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE void usage(void) +{ + nrerror("usage:\n" + "RNAplfold [-L span]\n" + " [-T temp] [-4] [-d[0|1|2]] [-noGU] [-noCloseGU]\n" + " [-noLP] [-P paramfile] [-nsp pairs] [-noconv]\n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAplfold.o 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+extern int svg_rna_plot(char *string, char *structure, char *ssfile); + +int main(int argc, char *argv[]) +{ + + char *string=NULL, *line; + char *structure=NULL, *pre=NULL, *post=NULL; + char fname[13], ffname[20]; + int i, r; + float energy; + int istty; + char format[5]="ps"; + + string=NULL; + for (i=1; i')) { + if (*line=='>') + sscanf(line, ">%12s", fname); + printf("%s\n", line); + free(line); + if ((line = get_line(stdin))==NULL) line = "@"; + } + + if (strcmp(line, "@") == 0) break; + + string = (char *) space(strlen(line)+1); + sscanf(line,"%s",string); + free(line); + + if ((line = get_line(stdin))==NULL) break; + structure = (char *) space(strlen(line)+1); + sscanf(line,"%s (%f)", structure, &energy); + free(line); + + if (strlen(string)!=strlen(structure)) + nrerror("sequence and structure have unequal length!"); + + if (fname[0]!='\0') { + strcpy(ffname, fname); + strcat(ffname, "_ss"); + } else + strcpy(ffname, "rna"); + + switch (format[0]) { + case 'p': + strcat(ffname, ".ps"); + PS_rna_plot_a(string, structure, ffname, pre, post); + break; + case 'g': + strcat(ffname, ".gml"); + gmlRNA(string, structure, ffname, 'x'); + break; + case 'x': + strcat(ffname, ".ss"); + xrna_plot(string, structure, ffname); + break; + case 's': + strcat(ffname, ".svg"); + svg_rna_plot(string, structure, ffname); + break; + default: + usage(); + } + fflush(stdout); + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE void usage(void) +{ + nrerror("usage: RNAplot [-t 0|1] [-o ps|gml|xrna|svg] [--pre ] [--post ]"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAplot.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAplot.o new file mode 100755 index 0000000000000000000000000000000000000000..d93f9766e657c25886d89d2903665a220b469edb GIT binary patch literal 13088 zcmbta4Rln;b)Kgui3JI*kT78I&jJFAV6A=(R2YmU5U`4cgN+e1n5G*Z@#(r&VBP{=Dk(_#+FTamL<4YVx7opj0({=H!C+tu|ZrZ=8Kn5 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAstats.c @@ -0,0 +1,363 @@ +/* + * RNA folding statistics program Based on RNAsubopt. + */ + +#include +#include +#include +#include +#include +#include +#include +#include "part_func.h" +#include "fold.h" +#include "fold_vars.h" +#include "utils.h" +#include "subopt.h" +extern void read_parameter_file(const char fname[]); +extern int st_back; +/* @unused@ */ +static char UNUSED rcsid[] = "$Id: RNAstats.c,v 1.0 2006/01/02 Exp $"; + +#define ENTROPY(X) (X==0 ? 0 : (-X*log2f(X))) + +#define PRIVATE static + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +extern double print_energy; +PRIVATE void usage(void); +float *bp_entropy(int length); +extern char *pbacktrack(char *sequence); +/*--------------------------------------------------------------------------*/ + +int +main(int argc, char *argv[]) +{ + char *line; + char *sequence; + char *ss = NULL; + char *ParamFile = NULL; + char *ns_bases = NULL, *c; + int i, length, l, sym, r; + double deltaf, deltap = 0; + int delta = 100; + int statType = 1; + int slideOffset = 1; + int slideWindow = 200; + + do_backtrack = 1; + dangles = 2; + + /* Read command line arguments ********************************************/ + + for (i = 1; i < argc; i++) { + if (argv[i][0] == '-') + switch (argv[i][1]) { + case 'T': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%lf", &temperature); + if (r != 1) + usage(); + break; + case 'S': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + (void) sscanf(argv[++i], "%d", &statType); + break; + case 'o': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + (void) sscanf(argv[++i], "%d", &slideOffset); + break; + case 'w': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + (void) sscanf(argv[++i], "%d", &slideWindow); + break; + case 'n': + if (strcmp(argv[i], "-noGU") == 0) + noGU = 1; + if (strcmp(argv[i], "-noCloseGU") == 0) + no_closingGU = 1; + if (strcmp(argv[i], "-noLP") == 0) + noLonelyPairs = 1; + if (strcmp(argv[i], "-nsp") == 0) { + if (i == argc - 1) + usage(); + ns_bases = argv[++i]; + } + break; + case '4': + tetra_loop = 0; + break; + case 'd': + dangles = 0; + if (argv[i][2] != '\0') { + r = sscanf(argv[i] + 2, "%d", &dangles); + if (r != 1) + usage(); + } + break; + case 'P': + if (i == argc - 1) + usage(); + ParamFile = argv[++i]; + break; + case 's': + subopt_sorted = 1; + break; + case 'l': + if (strcmp(argv[i], "-logML") == 0) { + logML = 1; + break; + } else + usage(); + break; + case 'e': + if (i >= argc - 1) + usage(); + if (strcmp(argv[i], "-ep") == 0) + r = sscanf(argv[++i], "%lf", &deltap); + else { + r = sscanf(argv[++i], "%lf", &deltaf); + delta = (int) (0.1 + deltaf * 100); + } + if (r != 1) + usage(); + break; + default: + usage(); + } + } + + if (ParamFile != NULL) + read_parameter_file(ParamFile); + + if (ns_bases != NULL) { + nonstandards = space(33); + c = ns_bases; + i = sym = 0; + if (*c == '-') { + sym = 1; + c++; + } + while (*c) { + if (*c != ',') { + nonstandards[i++] = *c++; + nonstandards[i++] = *c; + if ((sym) && (*c != *(c - 1))) { + nonstandards[i++] = *c; + nonstandards[i++] = *(c - 1); + } + } + c++; + } + } + + + /* Main Loop. Process each line as a sequence *****************************/ + + int mergePos = (int)(floor(((float)(slideWindow - slideOffset)) / 2)) + 1; + + do { + + /* Read sequence, make sure it's long enough and allocate memory for structure */ + + if ((line = get_line(stdin)) == NULL) + break; + + if (slideWindow > strlen(line)) + { + fprintf(stderr, "Sequence length (%d) should be at least window-length (%d)", strlen(line), slideWindow); + nrerror ("Quitting."); + } + + /* printf ("Sliding window %d\n", slideWindow); */ + + sequence = (char *) space(strlen(line) + 1); + (void) sscanf(line, "%s", sequence); + free(line); + + length = (int) strlen(sequence); + + for (l = 0; l < length; l++) + sequence[l] = toupper(sequence[l]); + + + /* Some deltap calculations */ + + if (logML != 0 || dangles == 1 || dangles == 3) + if (deltap <= 0) + deltap = delta / 100. + 0.001; + if (deltap > 0) + print_energy = deltap; + + int i, j; + double mfe, kT; + + int startPos; + char rememberBp; + + st_back = 1; + + /* Construct the sub-sequence to be processed, based on the window size + and offset. Then calculate the required statistics for each such sub-sequence */ + + ss = (char *) space((unsigned)(slideWindow + 1)); + + for (startPos = 0; startPos <= (length - slideWindow); startPos += slideOffset) + { + /* Crop the sequence at window size */ + + rememberBp = sequence[startPos + slideWindow]; + sequence[startPos + slideWindow] = 0; + + /* Initial folding of the sequence */ + + mfe = fold((char*)(sequence + startPos), ss); + + kT = (temperature + 273.15) * 1.98717 / 1000.; /* in Kcal */ + pf_scale = exp(-(1.03 * mfe) / kT / length); + + (void) pf_fold((char*)(sequence + startPos), NULL); + + float *bpProfile; + float *bpEntropy; + float basePairedP; + char na; + + /* Use the Make_bp_profile function to calculate the probability of + each bp to be paired. Then either print out this probability + or the entropy of this probability */ + + bpProfile = (float *)Make_bp_profile (slideWindow); + bpEntropy = (float *)bp_entropy (slideWindow); + + /* P[i*3+0] unpaired, P[i*3+1] upstream, P[i*3+2] downstream p */ + + /* First time only -- pad with data before mergePos */ + if (!startPos) + { + for (j = 1; j < mergePos; j++) + { + basePairedP = (1-bpProfile[j*3]); + na = sequence[startPos + j - 1]; + + printf("%d\t%d\tPairness\t%.2f\t%c\n", j, j, basePairedP, na); + printf("%d\t%d\tPairness_Entropy\t%.2f\t%c\n", j, j, ENTROPY(basePairedP) + ENTROPY((1-basePairedP)), na); + printf("%d\t%d\tEntropy\t%.2f\t%c\n", j, j, bpEntropy[j], na); + /* Not printing dG */ + } + } + + /* Always -- print center data */ + for (j = mergePos; j < mergePos + slideOffset; j++) + { + basePairedP = (1-bpProfile[j*3]); + na = sequence[startPos + j - 1]; + + printf("%d\t%d\tPairness\t%.2f\t%c\n", j+startPos, j+startPos, basePairedP, na); + printf("%d\t%d\tPairness_Entropy\t%.2f\t$c\n", j+startPos, j+startPos, ENTROPY(basePairedP) + ENTROPY((1-basePairedP)), na); + printf("%d\t%d\tEntropy\t%.2f\t%c\n", j+startPos, j+startPos, bpEntropy[j], na); + } + + /* Always -- print dG data (but only once) */ + printf("%d\t%d\tdG\t%.2f\n", startPos+mergePos, (startPos+mergePos+slideOffset-1), -mfe); + + /* Last time only -- pad with data after mergePos */ + if (startPos + slideOffset > length - slideWindow) + { + for (j = mergePos + slideOffset; j < slideWindow+1; j++) + { + basePairedP = (1-bpProfile[j*3]); + na = sequence[startPos + j - 1]; + + printf("%d\t%d\tPairness\t%.2f\t%c\n", j+startPos, j+startPos, basePairedP, na); + printf("%d\t%d\tPairness_Entropy\t%.2f\t%c\n", j+startPos, j+startPos, ENTROPY(basePairedP) + ENTROPY((1-basePairedP)), na); + printf("%d\t%d\tEntropy\t%.2f\t%c\n", j+startPos, j+startPos, bpEntropy[j], na); + } + } + + free (bpProfile); + free (bpEntropy); + + /* Restore the bp at the position where we placed the "0" beofre */ + sequence[startPos + slideWindow] = rememberBp; + } + + (void) fflush(stdout); + + free_pf_arrays(); + free(ss); + free(sequence); + + } while (1); + return 0; +} + +/******************************************************************************/ + +float *bp_entropy(int length) +{ + int i,j; + int L=3; + float *P; + float entropy; + + P = (float *) space((length)*sizeof(float)); + + for (i=1; iV*8@?;*_KcaRt!IXKYqO=}>0mg`Oh_w|0rNRf#%$KpqL5FP*YzthgYx;zWfIbQ z+HBe4JyS{RI`jRy%We|s)^mM-zQyk!ihP>+NFLv`n)zDIeAaWVNtpGt>c_hAZ=hMf zfoVmEFR0^%T57+N6WQ*$n4hAQ9(X;1Q74^9>W9^|bQcgnVWVOw9lNVbS@+ z`SX5u`RE_cpFLv!yt~Slj#yfF`H0I$k6d*3$jb!%h)dERA&q#)BHfjL*mV>`6{E^>h;xCmS=OE7C zx%jgriSfSt$NW+D`{8de{?5nWMfm#x{?5kV_x-%6Kyf_3Oh4Hp-EA^#X^-?jndt`7`=aG$T{lHwAYb@<0)I@O+avuaNbg3EiHH14O<##P zf4B6gS6n9B*5jE9Ut*?vd!)Z_rr*~iz1mEl(IdUoOrP2#eUVA$yFJn^8U3P1I^~eR z)%Z)L(+a=TBmF`O1AcY*vtSr+;y?KP5`U@b?}${JjqRM8Zq@5IJ<`{j@E7&qr==sz zmx_ma#oui`;QwIqVN{Rw+a$Q{7@nzkEIIsnk96t`+dZeF${QObRQ|Zw}s?GLvkMssJ{dzp9 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+extern int st_back; +/*@unused@*/ +static char UNUSED rcsid[] = "$Id: RNAsubopt.c,v 1.11 2004/08/12 10:59:31 ivo Exp $"; + +#define PRIVATE static + +static char scale[] = "....,....1....,....2....,....3....,....4" + "....,....5....,....6....,....7....,....8"; + +extern double print_energy; +PRIVATE void usage(void); +extern char *pbacktrack(char *sequence); +/*--------------------------------------------------------------------------*/ + +int main(int argc, char *argv[]) +{ + char *line; + char *sequence; + char *structure = NULL; + char fname[21]; + char *ParamFile = NULL; + char *ns_bases = NULL, *c; + int i, length, l, sym, r; + int istty; + double deltaf, deltap=0; + int delta=100; + int n_back = 0; + + do_backtrack = 1; + dangles = 2; + for (i=1; i=argc-1) usage(); + if (strcmp(argv[i],"-ep")==0) + r=sscanf(argv[++i], "%lf", &deltap); + else { + r=sscanf(argv[++i], "%lf", &deltaf); + delta = (int) (0.1+deltaf*100); + } + if (r!=1) usage(); + break; + default: usage(); + } + } + + if (ParamFile != NULL) + read_parameter_file(ParamFile); + + if (ns_bases != NULL) { + nonstandards = space(33); + c=ns_bases; + i=sym=0; + if (*c=='-') { + sym=1; c++; + } + while (*c) { + if (*c!=',') { + nonstandards[i++]=*c++; + nonstandards[i++]=*c; + if ((sym)&&(*c!=*(c-1))) { + nonstandards[i++]=*c; + nonstandards[i++]=*(c-1); + } + } + c++; + } + } + istty = isatty(fileno(stdout))&&isatty(fileno(stdin)); + if ((fold_constrained)&&(istty)) { + printf("Input constraints using the following notation:\n"); + /* printf("| : paired with another base\n"); */ + printf(". : no constraint at all\n"); + printf("x : base must not pair\n"); + } + + do { /* main loop: continue until end of file */ + if (istty) { + printf("\nInput string (upper or lower case); @ to quit\n"); + printf("%s\n", scale); + } + fname[0]='\0'; + if ((line = get_line(stdin))==NULL) break; + + /* skip comment lines and get filenames */ + while ((*line=='*')||(*line=='\0')||(*line=='>')) { + if (*line=='>') + (void) sscanf(line, ">%20s", fname); + free(line); + if ((line = get_line(stdin))==NULL) break;; + } + + if ((line==NULL) || strcmp(line, "@") == 0) break; + + sequence = (char *) space(strlen(line)+1); + (void) sscanf(line,"%s",sequence); + free(line); + length = (int) strlen(sequence); + + structure = (char *) space((unsigned) length+1); + if (fold_constrained) { + char *cstruc; + cstruc = get_line(stdin); + if (cstruc!=NULL) { + strncpy(structure, cstruc, length); + for (i=0; i0) + print_energy = deltap; + + /* first lines of output (suitable for sort +1n) */ + if (fname[0] != '\0') + printf("> %s [%d]\n", fname, delta); + + if (n_back>0) { + int i; + double mfe, kT; + char *ss; + st_back=1; + ss = (char *) space(strlen(sequence)+1); + strncpy(ss, structure, length); + mfe = fold(sequence, ss); + kT = (temperature+273.15)*1.98717/1000.; /* in Kcal */ + pf_scale = exp(-(1.03*mfe)/kT/length); + strncpy(ss, structure, length); + (void) pf_fold(sequence, ss); + init_rand(); + free(ss); + for (i=0; ijLx+UR&CR_e8tx7E0jOxA zBrPeTvDH@Fw8OL=hdOnJnRXDZwGrf@?aZK4t*w2iGqz-WK+#%!HM7>)Gj?^r9)!%z7$YA6NNeMqwzkA0K@f0d$LnkpC zIiC6|c3=QVCufh0j6icc?gQkSzLAu#p?^fOuIYQ<-+MpMe|RZ;)Rz6bM9W6%`elEr zdX^V8^aJHvp!yF??tM0OQ_lzUQ|s$?%kuj0PwGaFLJPZcv-}6ns}KK}3IOUG*)`2d zl|ikg*N&v-xHXu*c4QPE*wSAxC|gQ@sc!dG*b|6hHs;c`{$n!h8}j#k1HxIO{HO)} zfkS0OJ9hxp|G-e+A%EXSDBcZv-$=UVXiY&tkU3euu5YNW|FFMztL&Gr=YzTa`w#U# z>%V{KoD=)3)V!V#miv3RK(lrIzm^r=d|J*6DZA2}4@U(uIfJ`#oY@r4E6oTV9@$5 zh8D|Ssaf)-|L)gq=xGD=^jUx3Hh_1Zi@d%U{C&4!3A8N4&a;-kw-eNzXKjCP7zCKr z&qn=IVXnfbtP%B38#?1ZbUdeLM?nC}r@avMuYNx2UvoU_U;7-)>q%(I-}fO}g^3OQ zy5~X}qf_qmzb5Xv?&hXw(Mn>G3FqSlYJ5cml=S<#%xKa3PU}E>f-|!;f`43cE!!Ll~hI06) zAB~J?%YPljotOW5kf9fKdsY`*B|%=DgiTF+jCEE*9W4_71T->nPbHYB z-@W>mupwpbJXw@J&wt=**ft~SNgx2ymCgpi#w}u>+G#OLc^shOmt>O=8D$?@6g{}T z_O?So-Jb1Pa!-{(9sWDF-QKgxm~KOPx5 z+gGb_U)PhPOgAXciu=3;(EY_qdV6b^fQO&4Km5J9}VP z_M9Cjhd%&P{hqB>`?>R(y0W45Emh4`Ema$;f`@4~`^K8h5J-yCjWq>6*eXbyf1-a{!SIw1Mn)R? z{~-MvJ_$WPS#cJEk5?1;8{Pwp>g44T!Rz_(6Cj>E&(-&1`8Zd92)sM_{vXhS@?UcGtxy$*oKi8Q`S?-hNDCb43P&n;q=k;O$dML1QU#i|rdWC7row08D zXh

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This file is still incomplete and largely untested */ +/* It does not contain: */ +/* terminal mismatch energies for 1xn and 2x3 loops */ +/* we currently still use dangling ends instead of terminal mismatches */ +/* in multi-loops and the exterior loop. */ +/* There's no special parameters for co-axial stacking */ + +# stack_energies +/* CG GC GU UG AU UA @ */ + -220 -190 -20 -60 -130 -160 0 + -190 -220 -50 0 -160 -130 0 + -20 -50 130 80 -10 40 0 + -60 0 80 20 70 40 0 + -130 -160 -10 70 -80 -100 0 + -160 -130 40 40 -100 -60 0 + 0 0 0 0 0 0 0 + + +# stack_enthalpies +/* CG GC GU UG AU UA @ */ + -980 -750 -240 -430 -580 -990 0 + -750 -790 -240 430 -780 -850 0 + -240 -240 500 800 -170 -90 0 + -430 430 800 -670 370 -90 0 + -580 -780 -170 370 -530 -720 0 + -990 -850 -90 -90 -720 -670 0 + 0 0 0 0 0 0 0 + + +# dangle5 +/* N A C G T */ +/* NP */ INF INF INF INF INF +/* CG */ -50 -100 -50 -60 -80 +/* GC */ -40 -60 -40 -60 -60 +/* GT */ -40 -60 -40 -60 -60 +/* TG */ -50 -100 -50 -60 -80 +/* AT */ -40 -40 -40 -60 -80 +/* TA */ 70 -30 10 70 10 +/* NN */ 70 -30 10 70 10 + +# dangle3 +/* N A C G T */ +/* NP */ INF INF INF INF INF +/* CG */ -30 -90 -30 -50 -40 +/* GC */ 0 -100 -30 0 -50 +/* GT */ 0 -100 -30 0 -50 +/* TG */ -30 -90 -30 -50 -40 +/* AT */ -20 -40 -20 -50 -30 +/* TA */ 50 10 50 10 20 +/* NN */ 50 10 50 10 20 + +# dangle5_enthalpies +/* N A C G T */ +/* NP */ INF INF INF INF INF +/* CG */ -90 -620 -330 -510 -90 +/* GC */ -420 -460 -420 -470 -500 +/* GT */ -420 -460 -420 -470 -500 +/* TG */ -90 -620 -330 -510 -90 +/* AT */ -60 -90 -60 -250 -900 +/* TA */ 200 80 200 150 110 +/* NN */ 200 80 200 150 110 + +# dangle3_enthalpies +/* N A C G T */ +/* NP */ INF INF INF INF INF +/* CG */ -20 -190 -20 -400 -550 +/* GC */ -250 -800 -250 -310 -390 +/* GT */ -250 -800 -250 -310 -390 +/* TG */ -20 -190 -20 -400 -550 +/* AT */ 200 -530 200 -480 90 +/* TA */ 630 430 630 250 260 +/* NN */ 630 430 630 250 260 + +# int11_energies +/* CG..CG */ +/* N */ 160 90 160 90 90 +/* A */ 90 70 90 -20 90 +/* C */ 160 90 160 90 60 +/* G */ 90 -20 90 20 90 +/* T */ 90 90 60 90 0 +/* CG..GC */ +/* N */ 130 100 130 100 80 +/* A */ 50 50 10 -120 10 +/* C */ 130 100 130 100 80 +/* G */ 10 -40 10 -60 10 +/* T */ 100 100 70 100 70 +/* CG..GT */ +/* N */ 130 100 130 100 80 +/* A */ 50 50 10 -120 10 +/* C */ 130 100 130 100 80 +/* G */ 10 -40 10 -60 10 +/* T */ 100 100 70 100 70 +/* CG..TG */ +/* N */ 160 90 160 90 90 +/* A */ 90 70 90 -20 90 +/* C */ 160 90 160 90 60 +/* G */ 90 -20 90 20 90 +/* T */ 90 90 60 90 0 +/* CG..AT */ +/* N */ 180 120 180 120 110 +/* A */ 120 120 110 -80 110 +/* C */ 180 120 180 120 -60 +/* G */ 110 -10 110 -70 110 +/* T */ 120 120 0 120 -40 +/* CG..TA */ +/* N */ 220 140 220 140 170 +/* A */ 170 140 170 70 170 +/* C */ 220 140 220 140 120 +/* G */ 170 40 170 30 170 +/* T */ 140 140 120 140 80 +/* CG..NN */ +/* N */ 220 140 220 140 170 +/* A */ 170 140 170 70 170 +/* C */ 220 140 220 140 120 +/* G */ 170 40 170 30 170 +/* T */ 140 140 120 140 80 +/* GC..CG */ +/* N */ 130 50 130 10 100 +/* A */ 100 50 100 -40 100 +/* C */ 130 10 130 10 70 +/* G */ 100 -120 100 -60 100 +/* T */ 80 10 80 10 70 +/* GC..GC */ +/* N */ 100 40 100 40 90 +/* A */ 40 20 40 -150 40 +/* C */ 100 40 100 40 70 +/* G */ 40 -150 40 -180 40 +/* T */ 90 40 70 40 90 +/* GC..GT */ +/* N */ 100 40 100 40 90 +/* A */ 40 20 40 -150 40 +/* C */ 100 40 100 40 70 +/* G */ 40 -150 40 -180 40 +/* T */ 90 40 70 40 90 +/* GC..TG */ +/* N */ 130 50 130 10 100 +/* A */ 100 50 100 -40 100 +/* C */ 130 10 130 10 70 +/* G */ 100 -120 100 -60 100 +/* T */ 80 10 80 10 70 +/* GC..AT */ +/* N */ 260 140 260 130 160 +/* A */ 140 140 120 -20 120 +/* C */ 260 130 260 130 160 +/* G */ 120 10 120 -110 120 +/* T */ 130 130 90 130 90 +/* GC..TA */ +/* N */ 200 120 200 120 170 +/* A */ 170 70 170 70 170 +/* C */ 200 120 200 120 130 +/* G */ 170 40 170 50 170 +/* T */ 200 120 200 120 40 +/* GC..NN */ +/* N */ 260 140 260 130 170 +/* A */ 170 140 170 70 170 +/* C */ 260 130 260 130 160 +/* G */ 170 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+/* TA C ..GT */ + 580 550 580 550 580 /* N */ + 550 550 550 550 550 /* A */ + 580 550 580 550 580 /* C */ + 550 550 550 550 550 /* G */ + 580 550 580 550 580 /* T */ +/* TA G ..GT */ + 500 450 500 430 500 /* N */ + 450 450 450 430 450 /* A */ + 500 450 500 430 500 /* C */ + 430 430 430 430 430 /* G */ + 500 450 500 430 500 /* T */ +/* TA T ..GT */ + 550 550 510 550 420 /* N */ + 550 550 510 550 420 /* A */ + 510 510 510 510 420 /* C */ + 550 550 510 550 420 /* G */ + 420 420 420 420 420 /* T */ +/* TA N ..TG */ + 600 550 600 550 520 /* N */ + 550 550 550 550 520 /* A */ + 600 550 600 550 520 /* C */ + 550 550 550 550 500 /* G */ + 520 520 520 500 520 /* T */ +/* TA A ..TG */ + 520 520 520 420 520 /* N */ + 520 520 520 420 520 /* A */ + 520 520 520 420 520 /* C */ + 420 420 420 420 420 /* G */ + 520 520 520 420 520 /* T */ +/* TA C ..TG */ + 600 550 600 550 500 /* N */ + 550 550 550 550 500 /* A */ + 600 550 600 550 500 /* C */ + 550 550 550 550 500 /* G */ + 500 500 500 500 500 /* T */ +/* TA G ..TG */ + 520 450 520 410 520 /* N */ + 450 450 450 410 450 /* A */ + 520 450 520 410 520 /* C */ + 410 410 410 410 410 /* G */ + 520 450 520 410 520 /* T */ +/* TA T ..TG */ + 550 550 500 550 460 /* N */ + 550 550 500 550 460 /* A */ + 500 500 500 500 460 /* C */ + 550 550 500 550 460 /* G */ + 460 460 460 460 460 /* T */ +/* TA N ..AT */ + 610 530 610 530 510 /* N */ + 530 530 530 530 510 /* A */ + 610 530 610 530 510 /* C */ + 530 530 530 530 510 /* G */ + 510 510 510 510 510 /* T */ +/* TA A ..AT */ + 510 510 500 380 500 /* N */ + 510 510 500 380 500 /* A */ + 500 500 500 380 500 /* C */ + 380 380 380 380 380 /* G */ + 500 500 500 380 500 /* T */ +/* TA C ..AT */ + 610 530 610 530 510 /* N */ + 530 530 530 530 510 /* A */ + 610 530 610 530 510 /* C */ + 530 530 530 530 510 /* G */ + 510 510 510 510 510 /* T */ +/* TA G ..AT */ + 500 430 500 420 500 /* N */ + 430 430 430 420 430 /* A */ + 500 430 500 420 500 /* C */ + 420 420 420 420 420 /* G */ + 500 430 500 420 500 /* T */ +/* TA T ..AT */ + 530 530 500 530 410 /* N */ + 530 530 500 530 410 /* A */ + 500 500 500 500 410 /* C */ + 530 530 500 530 410 /* G */ + 410 410 410 410 410 /* T */ +/* TA N ..TA */ + 600 560 600 560 560 /* N */ + 560 560 560 560 540 /* A */ + 600 560 600 560 560 /* C */ + 560 560 560 560 500 /* G */ + 560 540 560 500 560 /* T */ +/* TA A ..TA */ + 560 540 560 470 560 /* N */ + 540 540 540 470 540 /* A */ + 560 540 560 470 560 /* C */ + 470 470 470 470 470 /* G */ + 560 540 560 470 560 /* T */ +/* TA C ..TA */ + 600 560 600 560 490 /* N */ + 560 560 560 560 490 /* A */ + 600 560 600 560 490 /* C */ + 560 560 560 560 490 /* G */ + 490 490 490 490 490 /* T */ +/* TA G ..TA */ + 560 470 560 480 560 /* N */ + 470 470 470 470 470 /* A */ + 560 470 560 480 560 /* C */ + 480 470 480 480 480 /* G */ + 560 470 560 480 560 /* T */ +/* TA T ..TA */ + 560 560 490 560 500 /* N */ + 560 560 490 560 500 /* A */ + 490 490 490 490 490 /* C */ + 560 560 490 560 500 /* G */ + 500 500 490 500 500 /* T */ +/* TA N ..NN */ + 610 560 610 560 580 /* N */ + 560 560 560 560 550 /* A */ + 610 560 610 560 580 /* C */ + 560 560 560 560 550 /* G */ + 580 550 580 550 580 /* T */ +/* TA A ..NN */ + 560 540 560 470 560 /* N */ + 540 540 540 470 540 /* A */ + 560 540 560 470 560 /* C */ + 470 470 470 470 470 /* G */ + 560 540 560 470 560 /* T */ +/* TA C ..NN */ + 610 560 610 560 580 /* N */ + 560 560 560 560 550 /* A */ + 610 560 610 560 580 /* C */ + 560 560 560 560 550 /* G */ + 580 550 580 550 580 /* T */ +/* TA G ..NN */ + 560 470 560 480 560 /* N */ + 470 470 470 470 470 /* A */ + 560 470 560 480 560 /* C */ + 480 470 480 480 480 /* G */ + 560 470 560 480 560 /* T */ +/* TA T ..NN */ + 560 560 510 560 500 /* N */ + 560 560 510 560 500 /* A */ + 510 510 510 510 490 /* C */ + 560 560 510 560 500 /* G */ + 500 500 490 500 500 /* T */ +/* NN N ..CG */ + 600 550 600 550 520 /* N */ + 550 550 550 550 520 /* A */ + 600 550 600 550 520 /* C */ + 550 550 550 550 500 /* G */ + 520 520 520 500 520 /* T */ +/* NN A ..CG */ + 520 520 520 420 520 /* N */ + 520 520 520 420 520 /* A */ + 520 520 520 420 520 /* C */ + 420 420 420 420 420 /* G */ + 520 520 520 420 520 /* T */ +/* NN C ..CG */ + 600 550 600 550 500 /* N */ + 550 550 550 550 500 /* A */ + 600 550 600 550 500 /* C */ + 550 550 550 550 500 /* G */ + 500 500 500 500 500 /* T */ +/* NN G ..CG */ + 520 450 520 410 520 /* N */ + 450 450 450 410 450 /* A */ + 520 450 520 410 520 /* C */ + 410 410 410 410 410 /* G */ + 520 450 520 410 520 /* T */ +/* NN T ..CG */ + 550 550 500 550 460 /* N */ + 550 550 500 550 460 /* A */ + 500 500 500 500 460 /* C */ + 550 550 500 550 460 /* G */ + 460 460 460 460 460 /* T */ +/* NN N ..GC */ + 640 550 640 550 580 /* N */ + 550 550 550 550 550 /* A */ + 640 550 640 550 580 /* C */ + 550 550 550 550 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN A ..GC */ + 520 520 510 420 510 /* N */ + 520 520 510 420 510 /* A */ + 510 510 510 420 510 /* C */ + 420 420 420 420 420 /* G */ + 510 510 510 420 510 /* T */ +/* NN C ..GC */ + 640 550 640 550 580 /* N */ + 550 550 550 550 550 /* A */ + 640 550 640 550 580 /* C */ + 550 550 550 550 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN G ..GC */ + 510 450 510 430 510 /* N */ + 450 450 450 430 450 /* A */ + 510 450 510 430 510 /* C */ + 430 430 430 430 430 /* G */ + 510 450 510 430 510 /* T */ +/* NN T ..GC */ + 550 550 540 550 470 /* N */ + 550 550 510 550 470 /* A */ + 540 510 540 510 470 /* C */ + 550 550 510 550 470 /* G */ + 470 470 470 470 470 /* T */ +/* NN N ..GT */ + 640 550 640 550 580 /* N */ + 550 550 550 550 550 /* A */ + 640 550 640 550 580 /* C */ + 550 550 550 550 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN A ..GT */ + 520 520 510 420 510 /* N */ + 520 520 510 420 510 /* A */ + 510 510 510 420 510 /* C */ + 420 420 420 420 420 /* G */ + 510 510 510 420 510 /* T */ +/* NN C ..GT */ + 640 550 640 550 580 /* N */ + 550 550 550 550 550 /* A */ + 640 550 640 550 580 /* C */ + 550 550 550 550 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN G ..GT */ + 510 450 510 430 510 /* N */ + 450 450 450 430 450 /* A */ + 510 450 510 430 510 /* C */ + 430 430 430 430 430 /* G */ + 510 450 510 430 510 /* T */ +/* NN T ..GT */ + 550 550 540 550 470 /* N */ + 550 550 510 550 470 /* A */ + 540 510 540 510 470 /* C */ + 550 550 510 550 470 /* G */ + 470 470 470 470 470 /* T */ +/* NN N ..TG */ + 600 550 600 550 520 /* N */ + 550 550 550 550 520 /* A */ + 600 550 600 550 520 /* C */ + 550 550 550 550 500 /* G */ + 520 520 520 500 520 /* T */ +/* NN A ..TG */ + 520 520 520 420 520 /* N */ + 520 520 520 420 520 /* A */ + 520 520 520 420 520 /* C */ + 420 420 420 420 420 /* G */ + 520 520 520 420 520 /* T */ +/* NN C ..TG */ + 600 550 600 550 500 /* N */ + 550 550 550 550 500 /* A */ + 600 550 600 550 500 /* C */ + 550 550 550 550 500 /* G */ + 500 500 500 500 500 /* T */ +/* NN G ..TG */ + 520 450 520 410 520 /* N */ + 450 450 450 410 450 /* A */ + 520 450 520 410 520 /* C */ + 410 410 410 410 410 /* G */ + 520 450 520 410 520 /* T */ +/* NN T ..TG */ + 550 550 500 550 460 /* N */ + 550 550 500 550 460 /* A */ + 500 500 500 500 460 /* C */ + 550 550 500 550 460 /* G */ + 460 460 460 460 460 /* T */ +/* NN N ..AT */ + 670 530 670 530 540 /* N */ + 530 530 530 530 510 /* A */ + 670 530 670 530 540 /* C */ + 530 530 530 530 510 /* G */ + 540 510 540 510 540 /* T */ +/* NN A ..AT */ + 520 520 500 380 500 /* N */ + 520 520 500 380 500 /* A */ + 500 500 500 380 500 /* C */ + 380 380 380 380 380 /* G */ + 500 500 500 380 500 /* T */ +/* NN C ..AT */ + 670 530 670 530 540 /* N */ + 530 530 530 530 510 /* A */ + 670 530 670 530 540 /* C */ + 530 530 530 530 510 /* G */ + 540 510 540 510 540 /* T */ +/* NN G ..AT */ + 500 430 500 420 500 /* N */ + 430 430 430 420 430 /* A */ + 500 430 500 420 500 /* C */ + 420 420 420 420 420 /* G */ + 500 430 500 420 500 /* T */ +/* NN T ..AT */ + 530 530 500 530 520 /* N */ + 530 530 500 530 480 /* A */ + 500 500 500 500 470 /* C */ + 530 530 500 530 480 /* G */ + 520 480 470 480 520 /* T */ +/* NN N ..TA */ + 610 560 610 560 560 /* N */ + 560 560 560 560 540 /* A */ + 610 560 610 560 560 /* C */ + 560 560 560 560 500 /* G */ + 560 540 560 500 560 /* T */ +/* NN A ..TA */ + 560 540 560 470 560 /* N */ + 540 540 540 470 540 /* A */ + 560 540 560 470 560 /* C */ + 470 470 470 470 470 /* G */ + 560 540 560 470 560 /* T */ +/* NN C ..TA */ + 610 560 610 560 510 /* N */ + 560 560 560 560 500 /* A */ + 610 560 610 560 510 /* C */ + 560 560 560 560 500 /* G */ + 510 500 510 500 510 /* T */ +/* NN G ..TA */ + 560 470 560 480 560 /* N */ + 470 470 470 470 470 /* A */ + 560 470 560 480 560 /* C */ + 480 470 480 480 480 /* G */ + 560 470 560 480 560 /* T */ +/* NN T ..TA */ + 580 560 580 560 500 /* N */ + 560 560 500 560 500 /* A */ + 580 500 580 500 490 /* C */ + 560 560 500 560 500 /* G */ + 500 500 490 500 500 /* T */ +/* NN N ..NN */ + 670 560 670 560 580 /* N */ + 560 560 560 560 550 /* A */ + 670 560 670 560 580 /* C */ + 560 560 560 560 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN A ..NN */ + 560 540 560 470 560 /* N */ + 540 540 540 470 540 /* A */ + 560 540 560 470 560 /* C */ + 470 470 470 470 470 /* G */ + 560 540 560 470 560 /* T */ +/* NN C ..NN */ + 670 560 670 560 580 /* N */ + 560 560 560 560 550 /* A */ + 670 560 670 560 580 /* C */ + 560 560 560 560 550 /* G */ + 580 550 580 550 580 /* T */ +/* NN G ..NN */ + 560 470 560 480 560 /* N */ + 470 470 470 470 470 /* A */ + 560 470 560 480 560 /* C */ + 480 470 480 480 480 /* G */ + 560 470 560 480 560 /* T */ +/* NN T ..NN */ + 580 560 580 560 520 /* N */ + 560 560 510 560 500 /* A */ + 580 510 580 510 490 /* C */ + 560 560 510 560 500 /* G */ + 520 500 490 500 520 /* T */ + +# int21_enthalpies +/* CG N ..CG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2500 2500 2500 2500 /* A */ + 2500 2500 2400 2500 2400 /* C */ + 2500 2500 2500 2500 2500 /* G */ + 2500 2500 2400 2500 2400 /* T */ +/* CG A ..CG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2290 2290 2500 2290 /* A */ + 2500 2290 2400 2500 2400 /* C */ + 2500 2500 2500 2500 2500 /* G */ + 2500 2290 2400 2500 2400 /* T */ +/* CG C ..CG */ + 2400 2400 2400 2400 2050 /* N */ + 2400 2400 2400 2400 2050 /* A */ + 2400 2400 2300 2400 2050 /* C */ + 2400 2400 2400 2400 2050 /* G */ + 2050 2050 2050 2050 2050 /* T */ +/* CG G ..CG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2500 2500 2500 2500 /* A */ + 2500 2500 2400 1900 2400 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 2500 2500 2400 1900 2400 /* T */ +/* CG T ..CG */ + 2400 2400 2050 2400 1620 /* N */ + 2400 2400 2050 2400 1620 /* A */ + 2050 2050 2050 2050 1620 /* C */ + 2400 2400 2050 2400 1620 /* G */ + 1620 1620 1620 1620 1620 /* T */ +/* CG N ..GC */ + 2820 2820 2820 2820 2350 /* N */ + 2820 2820 2820 2820 2350 /* A */ + 2820 2820 2640 2820 2350 /* C */ + 2820 2820 2820 2820 2100 /* G */ + 2350 2350 2350 2100 2350 /* T */ +/* CG A ..GC */ + 2350 2350 2350 2020 2350 /* N */ + 2350 1830 2350 2020 2350 /* A */ + 2350 2350 2350 2020 2350 /* C */ + 2020 2020 2020 2020 2020 /* G */ + 2350 2350 2350 2020 2350 /* T */ +/* CG C ..GC */ + 2820 2820 2820 2820 2080 /* N */ + 2820 2820 2820 2820 2080 /* A */ + 2820 2820 2640 2820 2080 /* C */ + 2820 2820 2820 2820 2080 /* G */ + 2080 2080 2080 2080 2080 /* T */ +/* CG G ..GC */ + 2350 2280 2350 1800 2350 /* N */ + 2280 2280 2280 1800 2280 /* A */ + 2350 2280 2350 1800 2350 /* C */ + 1800 1800 1800 1800 1800 /* G */ + 2350 2280 2350 1800 2350 /* T */ +/* CG T ..GC */ + 2820 2820 2100 2820 2100 /* N */ + 2820 2820 1940 2820 2100 /* A */ + 1940 1940 1940 1940 1940 /* C */ + 2820 2820 1940 2820 2100 /* G */ + 2100 2100 2100 2100 2100 /* T */ +/* CG N ..GT */ + 2820 2820 2820 2820 2350 /* N */ + 2820 2820 2820 2820 2350 /* A */ + 2820 2820 2640 2820 2350 /* C */ + 2820 2820 2820 2820 2100 /* G */ + 2350 2350 2350 2100 2350 /* T */ +/* CG A ..GT */ + 2350 2350 2350 2020 2350 /* N */ + 2350 1830 2350 2020 2350 /* A */ + 2350 2350 2350 2020 2350 /* C */ + 2020 2020 2020 2020 2020 /* G */ + 2350 2350 2350 2020 2350 /* T */ +/* CG C ..GT */ + 2820 2820 2820 2820 2080 /* N */ + 2820 2820 2820 2820 2080 /* A */ + 2820 2820 2640 2820 2080 /* C */ + 2820 2820 2820 2820 2080 /* G */ + 2080 2080 2080 2080 2080 /* T */ +/* CG G ..GT */ + 2350 2280 2350 1800 2350 /* N */ + 2280 2280 2280 1800 2280 /* A */ + 2350 2280 2350 1800 2350 /* C */ + 1800 1800 1800 1800 1800 /* G */ + 2350 2280 2350 1800 2350 /* T */ +/* CG T ..GT */ + 2820 2820 2100 2820 2100 /* N */ + 2820 2820 1940 2820 2100 /* A */ + 1940 1940 1940 1940 1940 /* C */ + 2820 2820 1940 2820 2100 /* G */ + 2100 2100 2100 2100 2100 /* T */ +/* CG N ..TG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2500 2500 2500 2500 /* A */ + 2500 2500 2400 2500 2400 /* C */ + 2500 2500 2500 2500 2500 /* G */ + 2500 2500 2400 2500 2400 /* T */ +/* CG A ..TG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2290 2290 2500 2290 /* A */ + 2500 2290 2400 2500 2400 /* C */ + 2500 2500 2500 2500 2500 /* G */ + 2500 2290 2400 2500 2400 /* T */ +/* CG C ..TG */ + 2400 2400 2400 2400 2050 /* N */ + 2400 2400 2400 2400 2050 /* A */ + 2400 2400 2300 2400 2050 /* C */ + 2400 2400 2400 2400 2050 /* G */ + 2050 2050 2050 2050 2050 /* T */ +/* CG G ..TG */ + 2500 2500 2500 2500 2500 /* N */ + 2500 2500 2500 2500 2500 /* A */ + 2500 2500 2400 1900 2400 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 2500 2500 2400 1900 2400 /* T */ +/* CG T ..TG */ + 2400 2400 2050 2400 1620 /* N */ + 2400 2400 2050 2400 1620 /* A */ + 2050 2050 2050 2050 1620 /* C */ + 2400 2400 2050 2400 1620 /* G */ + 1620 1620 1620 1620 1620 /* T */ +/* CG N ..AT */ + 2420 2420 2420 2280 2420 /* N */ + 2420 2390 2420 2280 2420 /* A */ + 2420 2420 2420 2280 2420 /* C */ + 2280 2280 2280 2280 1670 /* G */ + 2420 2420 2420 1670 2420 /* T */ +/* CG A ..AT */ + 2420 2420 2420 1670 2420 /* N */ + 2420 2390 2420 1670 2420 /* A */ + 2420 2420 2420 1670 2420 /* C */ + 1670 1670 1670 1670 1670 /* G */ + 2420 2420 2420 1670 2420 /* T */ +/* CG C ..AT */ + 2280 2280 2280 2280 660 /* N */ + 2280 2280 2280 2280 660 /* A */ + 2280 2280 2150 2280 660 /* C */ + 2280 2280 2280 2280 660 /* G */ + 660 660 660 660 660 /* T */ +/* CG G ..AT */ + 2420 1260 2420 900 2420 /* N */ + 1260 1260 1260 900 1260 /* A */ + 2420 1260 2420 900 2420 /* C */ + 900 900 900 900 900 /* G */ + 2420 1260 2420 900 2420 /* T */ +/* CG T ..AT */ + 2280 2280 1400 2280 1140 /* N */ + 2280 2280 1400 2280 1140 /* A */ + 1400 1400 1400 1400 1140 /* C */ + 2280 2280 1400 2280 1140 /* G */ + 1140 1140 1140 1140 1140 /* T */ +/* CG N ..TA */ + 3210 3020 3210 3020 3210 /* N */ + 3020 2890 2890 3020 2890 /* A */ + 3210 2890 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2890 3210 3020 3210 /* T */ +/* CG A ..TA */ + 3210 3020 3210 3020 3210 /* N */ + 3020 2890 2890 3020 2890 /* A */ + 3210 2890 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2890 3210 3020 3210 /* T */ +/* CG C ..TA */ + 2850 2850 2850 2850 1900 /* N */ + 2850 2850 2850 2850 1900 /* A */ + 2850 2850 2480 2850 1900 /* C */ + 2850 2850 2850 2850 1900 /* G */ + 1900 1900 1900 1900 1900 /* T */ +/* CG G ..TA */ + 3210 2580 3210 1780 3210 /* N */ + 2580 2580 2580 1780 2580 /* A */ + 3210 2580 3210 1780 3210 /* C */ + 1780 1780 1780 1780 1780 /* G */ + 3210 2580 3210 1780 3210 /* T */ +/* CG T ..TA */ + 2850 2850 2190 2850 1960 /* N */ + 2850 2850 2190 2850 1960 /* A */ + 2190 2190 2190 2190 1960 /* C */ + 2850 2850 2190 2850 1960 /* G */ + 1960 1960 1960 1960 1960 /* T */ +/* CG N ..NN */ + 3210 3020 3210 3020 3210 /* N */ + 3020 2890 2890 3020 2890 /* A */ + 3210 2890 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2890 3210 3020 3210 /* T */ +/* CG A ..NN */ + 3210 3020 3210 3020 3210 /* N */ + 3020 2890 2890 3020 2890 /* A */ + 3210 2890 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2890 3210 3020 3210 /* T */ +/* CG C ..NN */ + 2850 2850 2850 2850 2080 /* N */ + 2850 2850 2850 2850 2080 /* A */ + 2850 2850 2640 2850 2080 /* C */ + 2850 2850 2850 2850 2080 /* G */ + 2080 2080 2080 2080 2080 /* T */ +/* CG G ..NN */ + 3210 2580 3210 2500 3210 /* N */ + 2580 2580 2580 2500 2580 /* A */ + 3210 2580 3210 1900 3210 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 3210 2580 3210 1900 3210 /* T */ +/* CG T ..NN */ + 2850 2850 2190 2850 2100 /* N */ + 2850 2850 2190 2850 2100 /* A */ + 2190 2190 2190 2190 1960 /* C */ + 2850 2850 2190 2850 2100 /* G */ + 2100 2100 2100 2100 2100 /* T */ +/* GC N ..CG */ + 2820 2350 2820 2350 2820 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2820 2350 2820 2350 2820 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2820 2350 2820 2350 2820 /* T */ +/* GC A ..CG */ + 2820 2280 2820 2280 2820 /* N */ + 2280 1830 1830 2280 1830 /* A */ + 2820 1830 2820 2280 2820 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2820 1830 2820 2280 2820 /* T */ +/* GC C ..CG */ + 2640 2350 2640 2350 2350 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2640 2350 2640 2350 1940 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2350 2350 1940 2350 1940 /* T */ +/* GC G ..CG */ + 2820 2020 2820 2020 2820 /* N */ + 2020 2020 2020 2020 2020 /* A */ + 2820 2020 2820 1800 2820 /* C */ + 2020 2020 1800 1800 1800 /* G */ + 2820 2020 2820 1800 2820 /* T */ +/* GC T ..CG */ + 2350 2350 2350 2350 2350 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2350 2350 2080 2350 2100 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2350 2350 2100 2350 2100 /* T */ +/* GC N ..GC */ + 2490 2280 2490 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2490 2280 2490 2280 2280 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 2280 2280 2280 /* T */ +/* GC A ..GC */ + 2280 2150 2280 2130 2280 /* N */ + 2150 2150 2150 2130 2150 /* A */ + 2280 2150 2280 2130 2280 /* C */ + 2130 2130 2130 2130 2130 /* G */ + 2280 2150 2280 2130 2280 /* T */ +/* GC C ..GC */ + 2490 2280 2490 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2490 2280 2490 2280 1830 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 1830 2280 1830 /* T */ +/* GC G ..GC */ + 2280 2130 2280 1610 2280 /* N */ + 2130 2130 2130 1610 2130 /* A */ + 2280 2130 2280 1610 2280 /* C */ + 1610 1610 1610 1610 1610 /* G */ + 2280 2130 2280 1610 2280 /* T */ +/* GC T ..GC */ + 2280 2280 2280 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2280 2280 1830 2280 1830 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 1830 2280 1920 /* T */ +/* GC N ..GT */ + 2490 2280 2490 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2490 2280 2490 2280 2280 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 2280 2280 2280 /* T */ +/* GC A ..GT */ + 2280 2150 2280 2130 2280 /* N */ + 2150 2150 2150 2130 2150 /* A */ + 2280 2150 2280 2130 2280 /* C */ + 2130 2130 2130 2130 2130 /* G */ + 2280 2150 2280 2130 2280 /* T */ +/* GC C ..GT */ + 2490 2280 2490 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2490 2280 2490 2280 1830 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 1830 2280 1830 /* T */ +/* GC G ..GT */ + 2280 2130 2280 1610 2280 /* N */ + 2130 2130 2130 1610 2130 /* A */ + 2280 2130 2280 1610 2280 /* C */ + 1610 1610 1610 1610 1610 /* G */ + 2280 2130 2280 1610 2280 /* T */ +/* GC T ..GT */ + 2280 2280 2280 2280 2280 /* N */ + 2280 2280 2280 2280 2280 /* A */ + 2280 2280 1830 2280 1830 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2280 2280 1830 2280 1920 /* T */ +/* GC N ..TG */ + 2820 2350 2820 2350 2820 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2820 2350 2820 2350 2820 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2820 2350 2820 2350 2820 /* T */ +/* GC A ..TG */ + 2820 2280 2820 2280 2820 /* N */ + 2280 1830 1830 2280 1830 /* A */ + 2820 1830 2820 2280 2820 /* C */ + 2280 2280 2280 2280 2280 /* G */ + 2820 1830 2820 2280 2820 /* T */ +/* GC C ..TG */ + 2640 2350 2640 2350 2350 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2640 2350 2640 2350 1940 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2350 2350 1940 2350 1940 /* T */ +/* GC G ..TG */ + 2820 2020 2820 2020 2820 /* N */ + 2020 2020 2020 2020 2020 /* A */ + 2820 2020 2820 1800 2820 /* C */ + 2020 2020 1800 1800 1800 /* G */ + 2820 2020 2820 1800 2820 /* T */ +/* GC T ..TG */ + 2350 2350 2350 2350 2350 /* N */ + 2350 2350 2350 2350 2350 /* A */ + 2350 2350 2080 2350 2100 /* C */ + 2350 2350 2350 2350 2350 /* G */ + 2350 2350 2100 2350 2100 /* T */ +/* GC N ..AT */ + 3170 2980 3170 2980 3050 /* N */ + 2980 2980 2980 2980 2980 /* A */ + 3170 2980 3170 2980 3050 /* C */ + 2980 2980 2980 2980 2980 /* G */ + 3050 2980 3050 2980 3050 /* T */ +/* GC A ..AT */ + 2890 2890 2340 2340 2340 /* N */ + 2890 2890 2300 2340 2300 /* A */ + 2340 2300 2300 2340 2300 /* C */ + 2340 2340 2340 2340 2340 /* G */ + 2340 2300 2300 2340 2300 /* T */ +/* GC C ..AT */ + 3170 2980 3170 2980 3050 /* N */ + 2980 2980 2980 2980 2980 /* A */ + 3170 2980 3170 2980 3050 /* C */ + 2980 2980 2980 2980 2980 /* G */ + 3050 2980 3050 2980 3050 /* T */ +/* GC G ..AT */ + 2780 2780 2780 1390 2780 /* N */ + 2780 2780 2780 1390 2780 /* A */ + 2780 2780 2300 1390 2300 /* C */ + 1390 1390 1390 1390 1390 /* G */ + 2780 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..TA */ + 2310 2310 2310 2310 890 /* N */ + 2310 2310 2310 2310 890 /* A */ + 2310 2310 2260 2310 890 /* C */ + 2310 2310 2310 2310 890 /* G */ + 890 890 890 890 890 /* T */ +/* GC N ..NN */ + 3210 3020 3210 3020 3210 /* N */ + 2980 2980 2980 2980 2980 /* A */ + 3210 2980 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2980 3210 3020 3210 /* T */ +/* GC A ..NN */ + 3210 3020 3210 3020 3210 /* N */ + 2890 2890 2300 2340 2300 /* A */ + 3210 2300 3210 3020 3210 /* C */ + 3020 3020 3020 3020 3020 /* G */ + 3210 2300 3210 3020 3210 /* T */ +/* GC C ..NN */ + 3180 2980 3180 2980 3050 /* N */ + 2980 2980 2980 2980 2980 /* A */ + 3180 2980 3180 2980 3050 /* C */ + 2980 2980 2980 2980 2980 /* G */ + 3050 2980 3050 2980 3050 /* T */ +/* GC G ..NN */ + 3210 2780 3210 2580 3210 /* N */ + 2780 2780 2780 2580 2780 /* A */ + 3210 2780 3210 2230 3210 /* C */ + 2580 2580 2230 2230 2230 /* G */ + 3210 2780 3210 2230 3210 /* T */ +/* GC T ..NN */ + 2980 2980 2350 2980 2350 /* N */ + 2980 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2850 2850 2850 2850 2080 /* N */ + 2850 2850 2850 2850 2080 /* A */ + 2850 2850 2640 2850 2080 /* C */ + 2850 2850 2850 2850 2080 /* G */ + 2080 2080 2080 2080 2080 /* T */ +/* TG G ..NN */ + 3210 2580 3210 2500 3210 /* N */ + 2580 2580 2580 2500 2580 /* A */ + 3210 2580 3210 1900 3210 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 3210 2580 3210 1900 3210 /* T */ +/* TG T ..NN */ + 2850 2850 2190 2850 2100 /* N */ + 2850 2850 2190 2850 2100 /* A */ + 2190 2190 2190 2190 1960 /* C */ + 2850 2850 2190 2850 2100 /* G */ + 2100 2100 2100 2100 2100 /* T */ +/* AT N ..CG */ + 2420 2420 2420 2420 2390 /* N */ + 2420 2420 2420 2420 2390 /* A */ + 2420 2420 2280 2420 2280 /* C */ + 2420 2420 2420 2420 1400 /* G */ + 2280 2280 2280 1400 2280 /* T */ +/* AT A ..CG */ + 2390 2390 2390 1260 2390 /* N */ + 2390 2390 2390 1260 2390 /* A */ + 2280 2280 2280 1260 2280 /* C */ + 1260 1260 1260 1260 1260 /* G */ + 2280 2280 2280 1260 2280 /* T */ +/* AT C ..CG */ + 2420 2420 2420 2420 1400 /* N */ + 2420 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/* C */ + 2300 2300 2300 2300 2020 /* G */ + 2020 2020 2020 2020 2020 /* T */ +/* AT G ..GC */ + 2980 2340 2980 1390 2980 /* N */ + 2340 2340 2340 1390 2340 /* A */ + 2980 2340 2980 1390 2980 /* C */ + 1390 1390 1390 1390 1390 /* G */ + 2980 2340 2980 1390 2980 /* T */ +/* AT T ..GC */ + 3050 2300 3050 2300 1940 /* N */ + 2300 2300 2300 2300 1940 /* A */ + 3050 2300 3050 2300 1940 /* C */ + 2300 2300 2300 2300 1940 /* G */ + 1940 1940 1940 1940 1940 /* T */ +/* AT N ..GT */ + 3170 2980 3170 2780 2980 /* N */ + 2980 2890 2980 2780 2980 /* A */ + 3170 2980 3170 2780 2980 /* C */ + 2780 2780 2780 2780 2780 /* G */ + 2980 2980 2980 2780 2980 /* T */ +/* AT A ..GT */ + 2980 2980 2980 2780 2980 /* N */ + 2980 2890 2980 2780 2980 /* A */ + 2980 2980 2980 2780 2980 /* C */ + 2780 2780 2780 2780 2780 /* G */ + 2980 2980 2980 2780 2980 /* T */ +/* AT C ..GT */ + 3170 2300 3170 2300 2020 /* N */ + 2300 2300 2300 2300 2020 /* A */ + 3170 2300 3170 2300 2020 /* C */ + 2300 2300 2300 2300 2020 /* G */ + 2020 2020 2020 2020 2020 /* T */ +/* AT G ..GT */ + 2980 2340 2980 1390 2980 /* N */ + 2340 2340 2340 1390 2340 /* A */ + 2980 2340 2980 1390 2980 /* C */ + 1390 1390 1390 1390 1390 /* G */ + 2980 2340 2980 1390 2980 /* T */ +/* AT T ..GT */ + 3050 2300 3050 2300 1940 /* N */ + 2300 2300 2300 2300 1940 /* A */ + 3050 2300 3050 2300 1940 /* C */ + 2300 2300 2300 2300 1940 /* G */ + 1940 1940 1940 1940 1940 /* T */ +/* AT N ..TG */ + 2420 2420 2420 2420 2390 /* N */ + 2420 2420 2420 2420 2390 /* A */ + 2420 2420 2280 2420 2280 /* C */ + 2420 2420 2420 2420 1400 /* G */ + 2280 2280 2280 1400 2280 /* T */ +/* AT A ..TG */ + 2390 2390 2390 1260 2390 /* N */ + 2390 2390 2390 1260 2390 /* A */ + 2280 2280 2280 1260 2280 /* C */ + 1260 1260 1260 1260 1260 /* G */ + 2280 2280 2280 1260 2280 /* T */ +/* AT C ..TG */ + 2420 2420 2420 2420 1400 /* N */ + 2420 2420 2420 2420 1400 /* A */ + 2420 2420 2150 2420 1400 /* C */ + 2420 2420 2420 2420 1400 /* G */ + 1400 1400 1400 1400 1400 /* T */ +/* AT G ..TG */ + 2280 1670 2280 1670 2280 /* N */ + 1670 1670 1670 1670 1670 /* A */ + 2280 1670 2280 900 2280 /* C */ + 1670 1670 900 900 900 /* G */ + 2280 1670 2280 900 2280 /* T */ +/* AT T ..TG */ + 2420 2420 660 2420 1140 /* N */ + 2420 2420 660 2420 1140 /* A */ + 660 660 660 660 660 /* C */ + 2420 2420 660 2420 1140 /* G */ + 1140 1140 660 1140 1140 /* T */ +/* AT N ..AT */ + 2870 2870 2870 2870 2870 /* N */ + 2870 2870 2870 2870 2870 /* A */ + 2870 2870 2870 2870 2870 /* C */ + 2870 2870 2870 2870 2870 /* G */ + 2870 2870 2870 2870 2870 /* T */ +/* AT A ..AT */ + 2870 2870 2870 2600 2870 /* N */ + 2870 2380 2870 2600 2380 /* A */ + 2870 2870 2870 2600 2870 /* C */ + 2600 2600 2600 2600 2600 /* G */ + 2870 2870 2870 2600 2870 /* T */ +/* AT C ..AT */ + 2870 2870 2870 2870 2320 /* N */ + 2870 2870 2870 2870 2320 /* A */ + 2870 2870 2640 2870 2320 /* C */ + 2870 2870 2870 2870 2320 /* G */ + 2320 2320 2320 2320 2320 /* T */ +/* AT G ..AT */ + 2870 2600 2870 2600 2870 /* N */ + 2600 2600 2600 2600 2600 /* A */ + 2870 2600 2870 2300 2870 /* C */ + 2600 2600 2300 2300 2300 /* G */ + 2870 2600 2870 2300 2870 /* T */ +/* AT T ..AT */ + 2870 2870 2320 2870 2870 /* N */ + 2870 2870 2320 2870 2870 /* A */ + 2320 2320 2320 2320 2320 /* C */ + 2870 2870 2320 2870 2870 /* G */ + 2870 2870 2320 2870 2460 /* T */ +/* AT N ..TA */ + 3360 3180 3360 2960 3180 /* N */ + 3180 3180 3180 2960 3180 /* A */ + 3360 3180 3360 2960 2040 /* C */ + 2960 2960 2960 2960 2960 /* G */ + 3180 3180 2040 2960 2040 /* T */ +/* AT A ..TA */ + 3180 3180 3180 2960 3180 /* N */ + 3180 3180 3180 2960 3180 /* A */ + 3180 3180 2040 2960 2040 /* C */ + 2960 2960 2960 2960 2960 /* G */ + 3180 3180 2040 2960 2040 /* T */ +/* AT C ..TA */ + 3360 2930 3360 2930 2930 /* N */ + 2930 2930 2930 2930 2930 /* A */ + 3360 2930 3360 2930 1730 /* C */ + 2930 2930 2930 2930 2930 /* G */ + 1730 1730 1730 1730 1730 /* T */ +/* AT G ..TA */ + 2070 2070 2070 2070 2070 /* N */ + 2070 2070 2070 2070 2070 /* A */ + 2070 2070 2040 2050 2040 /* C */ + 2070 2070 2050 2050 2050 /* G */ + 2070 2070 2040 2050 2040 /* T */ +/* AT T ..TA */ + 2930 2930 2930 2930 1410 /* N */ + 2930 2930 2930 2930 1410 /* A */ + 2930 2930 2240 2930 1410 /* C */ + 2930 2930 2930 2930 1410 /* G */ + 1410 1410 1410 1410 1410 /* T */ +/* AT N ..NN */ + 3360 3180 3360 2960 3180 /* N */ + 3180 3180 3180 2960 3180 /* A */ + 3360 3180 3360 2960 2980 /* C */ + 2960 2960 2960 2960 2960 /* G */ + 3180 3180 2980 2960 2980 /* T */ +/* AT A ..NN */ + 3180 3180 3180 2960 3180 /* N */ + 3180 3180 3180 2960 3180 /* A */ + 3180 3180 2980 2960 2980 /* C */ + 2960 2960 2960 2960 2960 /* G */ + 3180 3180 2980 2960 2980 /* T */ +/* AT C ..NN */ + 3360 2930 3360 2930 2930 /* N */ + 2930 2930 2930 2930 2930 /* A */ + 3360 2930 3360 2930 2320 /* C */ + 2930 2930 2930 2930 2930 /* G */ + 2320 2320 2320 2320 2320 /* T */ +/* AT G ..NN */ + 2980 2600 2980 2600 2980 /* N */ + 2600 2600 2600 2600 2600 /* A */ + 2980 2600 2980 2300 2980 /* C */ + 2600 2600 2300 2300 2300 /* G */ + 2980 2600 2980 2300 2980 /* T */ +/* AT T ..NN */ + 3050 2930 3050 2930 2870 /* N */ + 2930 2930 2930 2930 2870 /* A */ + 3050 2930 3050 2930 2320 /* C */ + 2930 2930 2930 2930 2870 /* G */ + 2870 2870 2320 2870 2460 /* T */ +/* TA N ..CG */ + 3210 3210 3210 3210 3020 /* N */ + 3210 3210 3210 3210 3020 /* A */ + 3210 3210 2850 3210 2850 /* C */ + 3210 3210 3210 3210 2580 /* G */ + 3020 3020 2850 2580 2850 /* T */ +/* TA A ..CG */ + 2890 2890 2890 2580 2890 /* N */ + 2890 2890 2890 2580 2890 /* A */ + 2850 2850 2850 2580 2850 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2850 2850 2850 2580 2850 /* T */ +/* TA C ..CG */ + 3210 3210 3210 3210 2190 /* N */ + 3210 3210 3210 3210 2190 /* A */ + 3210 3210 2480 3210 2190 /* C */ + 3210 3210 3210 3210 2190 /* G */ + 2190 2190 2190 2190 2190 /* T */ +/* TA G ..CG */ + 3020 3020 3020 1780 3020 /* N */ + 3020 3020 3020 1780 3020 /* A */ + 3020 3020 2850 1780 2850 /* C */ + 1780 1780 1780 1780 1780 /* G */ + 3020 3020 2850 1780 2850 /* T */ +/* TA T ..CG */ + 3210 3210 1960 3210 1960 /* N */ + 3210 3210 1900 3210 1960 /* A */ + 1960 1900 1900 1900 1960 /* C */ + 3210 3210 1900 3210 1960 /* G */ + 1960 1960 1960 1960 1960 /* T */ +/* TA N ..GC */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2310 3210 2310 /* T */ +/* TA A ..GC */ + 2580 2580 2580 2580 2580 /* N */ + 2580 1750 1750 2580 1750 /* A */ + 2580 1750 2310 2580 2310 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2580 1750 2310 2580 2310 /* T */ +/* TA C ..GC */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2260 3210 2260 /* T */ +/* TA G ..GC */ + 3020 3020 3020 2230 3020 /* N */ + 3020 3020 3020 2230 3020 /* A */ + 3020 3020 2310 2230 2310 /* C */ + 2230 2230 2230 2230 2230 /* G */ + 3020 3020 2310 2230 2310 /* T */ +/* TA T ..GC */ + 3210 3210 1850 3210 890 /* N */ + 3210 3210 1850 3210 890 /* A */ + 1850 1850 1850 1850 890 /* C */ + 3210 3210 1850 3210 890 /* G */ + 890 890 890 890 890 /* T */ +/* TA N ..GT */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2310 3210 2310 /* T */ +/* TA A ..GT */ + 2580 2580 2580 2580 2580 /* N */ + 2580 1750 1750 2580 1750 /* A */ + 2580 1750 2310 2580 2310 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2580 1750 2310 2580 2310 /* T */ +/* TA C ..GT */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2260 3210 2260 /* T */ +/* TA G ..GT */ + 3020 3020 3020 2230 3020 /* N */ + 3020 3020 3020 2230 3020 /* A */ + 3020 3020 2310 2230 2310 /* C */ + 2230 2230 2230 2230 2230 /* G */ + 3020 3020 2310 2230 2310 /* T */ +/* TA T ..GT */ + 3210 3210 1850 3210 890 /* N */ + 3210 3210 1850 3210 890 /* A */ + 1850 1850 1850 1850 890 /* C */ + 3210 3210 1850 3210 890 /* G */ + 890 890 890 890 890 /* T */ +/* TA N ..TG */ + 3210 3210 3210 3210 3020 /* N */ + 3210 3210 3210 3210 3020 /* A */ + 3210 3210 2850 3210 2850 /* C */ + 3210 3210 3210 3210 2580 /* G */ + 3020 3020 2850 2580 2850 /* T */ +/* TA A ..TG */ + 2890 2890 2890 2580 2890 /* N */ + 2890 2890 2890 2580 2890 /* A */ + 2850 2850 2850 2580 2850 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2850 2850 2850 2580 2850 /* T */ +/* TA C ..TG */ + 3210 3210 3210 3210 2190 /* N */ + 3210 3210 3210 3210 2190 /* A */ + 3210 3210 2480 3210 2190 /* C */ + 3210 3210 3210 3210 2190 /* G */ + 2190 2190 2190 2190 2190 /* T */ +/* TA G ..TG */ + 3020 3020 3020 1780 3020 /* N */ + 3020 3020 3020 1780 3020 /* A */ + 3020 3020 2850 1780 2850 /* C */ + 1780 1780 1780 1780 1780 /* G */ + 3020 3020 2850 1780 2850 /* T */ +/* TA T ..TG */ + 3210 3210 1960 3210 1960 /* N */ + 3210 3210 1900 3210 1960 /* A */ + 1960 1900 1900 1900 1960 /* C */ + 3210 3210 1900 3210 1960 /* G */ + 1960 1960 1960 1960 1960 /* T */ +/* TA N ..AT */ + 3360 3180 3360 2240 2960 /* N */ + 3180 3180 2960 2070 2960 /* A */ + 3360 2960 3360 2070 2930 /* C */ + 2240 2070 2070 2070 2240 /* G */ + 2960 2960 2930 2240 2930 /* T */ +/* TA A ..AT */ + 3180 3180 2930 2070 2930 /* N */ + 3180 3180 2930 2070 2930 /* A */ + 2930 2930 2930 2070 2930 /* C */ + 2070 2070 2070 2070 2070 /* G */ + 2930 2930 2930 2070 2930 /* T */ +/* TA C ..AT */ + 3360 2240 3360 2240 2240 /* N */ + 2240 2040 2040 2040 2240 /* A */ + 3360 2040 3360 2040 2240 /* C */ + 2240 2040 2040 2040 2240 /* G */ + 2240 2240 2240 2240 2240 /* T */ +/* TA G ..AT */ + 2960 2960 2960 2050 2960 /* N */ + 2960 2960 2960 2050 2960 /* A */ + 2960 2960 2930 2050 2930 /* C */ + 2050 2050 2050 2050 2050 /* G */ + 2960 2960 2930 2050 2930 /* T */ +/* TA T ..AT */ + 2040 2040 1730 2040 1410 /* N */ + 2040 2040 1730 2040 1410 /* A */ + 1730 1730 1730 1730 1410 /* C */ + 2040 2040 1730 2040 1410 /* G */ 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TA N ..NN */ + 3630 3320 3630 3320 3320 /* N */ + 3320 3320 3320 3320 3210 /* A */ + 3630 3320 3630 3320 3320 /* C */ + 3320 3320 3320 3320 3210 /* G */ + 3320 3210 3320 3210 3320 /* T */ +/* TA A ..NN */ + 3320 3180 3320 3080 3320 /* N */ + 3180 3180 3100 3080 3100 /* A */ + 3320 3100 3320 3080 3320 /* C */ + 3080 3080 3080 3080 3080 /* G */ + 3320 3100 3320 3080 3320 /* T */ +/* TA C ..NN */ + 3630 3320 3630 3320 3210 /* N */ + 3320 3320 3320 3320 3210 /* A */ + 3630 3320 3630 3320 3180 /* C */ + 3320 3320 3320 3320 3210 /* G */ + 3210 3210 2260 3210 2260 /* T */ +/* TA G ..NN */ + 3320 3080 3320 3080 3320 /* N */ + 3080 3080 3080 3080 3080 /* A */ + 3320 3080 3320 2730 3320 /* C */ + 3080 3080 2730 2730 2730 /* G */ + 3320 3080 3320 2730 3320 /* T */ +/* TA T ..NN */ + 3320 3320 2140 3320 2510 /* N */ + 3320 3320 2140 3320 2510 /* A */ + 2140 2140 2140 2140 2140 /* C */ + 3320 3320 2140 3320 2510 /* G */ + 2510 2510 2140 2510 2510 /* T */ +/* NN N ..CG */ + 3210 3210 3210 3210 3020 /* N */ + 3210 3210 3210 3210 3020 /* A */ + 3210 3210 2850 3210 2850 /* C */ + 3210 3210 3210 3210 2580 /* G */ + 3020 3020 2850 2580 2850 /* T */ +/* NN A ..CG */ + 2890 2890 2890 2580 2890 /* N */ + 2890 2890 2890 2580 2890 /* A */ + 2850 2850 2850 2580 2850 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2850 2850 2850 2580 2850 /* T */ +/* NN C ..CG */ + 3210 3210 3210 3210 2350 /* N */ + 3210 3210 3210 3210 2350 /* A */ + 3210 3210 2640 3210 2190 /* C */ + 3210 3210 3210 3210 2350 /* G */ + 2350 2350 2190 2350 2190 /* T */ +/* NN G ..CG */ + 3020 3020 3020 2500 3020 /* N */ + 3020 3020 3020 2500 3020 /* A */ + 3020 3020 2850 1900 2850 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 3020 3020 2850 1900 2850 /* T */ +/* NN T ..CG */ + 3210 3210 2350 3210 2350 /* N */ + 3210 3210 2350 3210 2350 /* A */ + 2350 2350 2080 2350 2100 /* C */ + 3210 3210 2350 3210 2350 /* G */ + 2350 2350 2100 2350 2100 /* T */ +/* NN N ..GC */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2980 3210 2980 /* T */ +/* NN A ..GC */ + 2980 2980 2980 2780 2980 /* N */ + 2980 2890 2980 2780 2980 /* A */ + 2980 2980 2980 2780 2980 /* C */ + 2780 2780 2780 2780 2780 /* G */ + 2980 2980 2980 2780 2980 /* T */ +/* NN C ..GC */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2260 3210 2260 /* T */ +/* NN G ..GC */ + 3020 3020 3020 2230 3020 /* N */ + 3020 3020 3020 2230 3020 /* A */ + 3020 3020 2980 2230 2980 /* C */ + 2230 2230 2230 2230 2230 /* G */ + 3020 3020 2980 2230 2980 /* T */ +/* NN T ..GC */ + 3210 3210 3050 3210 2280 /* N */ + 3210 3210 2300 3210 2280 /* A */ + 3050 2300 3050 2300 1940 /* C */ + 3210 3210 2300 3210 2280 /* G */ + 2280 2280 2100 2280 2100 /* T */ +/* NN N ..GT */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2980 3210 2980 /* T */ +/* NN A ..GT */ + 2980 2980 2980 2780 2980 /* N */ + 2980 2890 2980 2780 2980 /* A */ + 2980 2980 2980 2780 2980 /* C */ + 2780 2780 2780 2780 2780 /* G */ + 2980 2980 2980 2780 2980 /* T */ +/* NN C ..GT */ + 3210 3210 3210 3210 3210 /* N */ + 3210 3210 3210 3210 3210 /* A */ + 3210 3210 3180 3210 3180 /* C */ + 3210 3210 3210 3210 3210 /* G */ + 3210 3210 2260 3210 2260 /* T */ +/* NN G ..GT */ + 3020 3020 3020 2230 3020 /* N */ + 3020 3020 3020 2230 3020 /* A */ + 3020 3020 2980 2230 2980 /* C */ + 2230 2230 2230 2230 2230 /* G */ + 3020 3020 2980 2230 2980 /* T */ +/* NN T ..GT */ + 3210 3210 3050 3210 2280 /* N */ + 3210 3210 2300 3210 2280 /* A */ + 3050 2300 3050 2300 1940 /* C */ + 3210 3210 2300 3210 2280 /* G */ + 2280 2280 2100 2280 2100 /* T */ +/* NN N ..TG */ + 3210 3210 3210 3210 3020 /* N */ + 3210 3210 3210 3210 3020 /* A */ + 3210 3210 2850 3210 2850 /* C */ + 3210 3210 3210 3210 2580 /* G */ + 3020 3020 2850 2580 2850 /* T */ +/* NN A ..TG */ + 2890 2890 2890 2580 2890 /* N */ + 2890 2890 2890 2580 2890 /* A */ + 2850 2850 2850 2580 2850 /* C */ + 2580 2580 2580 2580 2580 /* G */ + 2850 2850 2850 2580 2850 /* T */ +/* NN C ..TG */ + 3210 3210 3210 3210 2350 /* N */ + 3210 3210 3210 3210 2350 /* A */ + 3210 3210 2640 3210 2190 /* C */ + 3210 3210 3210 3210 2350 /* G */ + 2350 2350 2190 2350 2190 /* T */ +/* NN G ..TG */ + 3020 3020 3020 2500 3020 /* N */ + 3020 3020 3020 2500 3020 /* A */ + 3020 3020 2850 1900 2850 /* C */ + 2500 2500 1900 1900 1900 /* G */ + 3020 3020 2850 1900 2850 /* T */ +/* NN T ..TG */ + 3210 3210 2350 3210 2350 /* N */ + 3210 3210 2350 3210 2350 /* A */ + 2350 2350 2080 2350 2100 /* C */ + 3210 3210 2350 3210 2350 /* G */ + 2350 2350 2100 2350 2100 /* T */ +/* NN N ..AT */ + 3360 3180 3360 2980 3050 /* N */ + 3180 3180 2980 2980 2980 /* A */ + 3360 2980 3360 2980 3050 /* C */ + 2980 2980 2980 2980 2980 /* G */ + 3050 2980 3050 2980 3050 /* T */ +/* NN A ..AT */ + 3180 3180 2930 2600 2930 /* N */ + 3180 3180 2930 2600 2930 /* A */ + 2930 2930 2930 2600 2930 /* C */ + 2600 2600 2600 2600 2600 /* G */ + 2930 2930 2930 2600 2930 /* T */ +/* NN C ..AT */ + 3360 2980 3360 2980 3050 /* N */ + 2980 2980 2980 2980 2980 /* A */ + 3360 2980 3360 2980 3050 /* C */ + 2980 2980 2980 2980 2980 /* G */ + 3050 2980 3050 2980 3050 /* T */ +/* NN G ..AT */ + 2960 2960 2960 2600 2960 /* N */ + 2960 2960 2960 2600 2960 /* A */ + 2960 2960 2930 2300 2930 /* C */ + 2600 2600 2300 2300 2300 /* G */ + 2960 2960 2930 2300 2930 /* T */ +/* NN T ..AT */ + 2980 2980 2320 2980 2870 /* N */ + 2980 2980 2320 2980 2870 /* A */ + 2320 2320 2320 2320 2320 /* C */ + 2980 2980 2320 2980 2870 /* G */ + 2870 2870 2320 2870 2460 /* T */ +/* NN N ..TA */ + 3630 3320 3630 3320 3320 /* N */ + 3320 3320 3320 3320 3180 /* A */ + 3630 3320 3630 3320 3320 /* C */ + 3320 3320 3320 3320 3080 /* G */ + 3320 3180 3320 3080 3320 /* T */ +/* NN A ..TA */ + 3320 3180 3320 3080 3320 /* N */ + 3180 3180 3180 3080 3180 /* A */ + 3320 3180 3320 3080 3320 /* C */ + 3080 3080 3080 3080 3080 /* G */ + 3320 3180 3320 3080 3320 /* T */ +/* NN C ..TA */ + 3630 3320 3630 3320 2930 /* N */ + 3320 3320 3320 3320 2930 /* A */ + 3630 3320 3630 3320 2140 /* C */ + 3320 3320 3320 3320 2930 /* G */ + 2310 2310 2140 2310 2140 /* T */ +/* NN G ..TA */ + 3320 3080 3320 3080 3320 /* N */ + 3080 3080 3080 3080 3080 /* A */ + 3320 3080 3320 2730 3320 /* C */ + 3080 3080 2730 2730 2730 /* G */ + 3320 3080 3320 2730 3320 /* T */ +/* NN T ..TA */ + 3320 3320 2930 3320 2510 /* N */ + 3320 3320 2930 3320 2510 /* A */ + 2930 2930 2260 2930 2140 /* C */ + 3320 3320 2930 3320 2510 /* G */ + 2510 2510 2140 2510 2510 /* T */ +/* NN N ..NN */ + 3630 3320 3630 3320 3320 /* N */ + 3320 3320 3320 3320 3210 /* A */ + 3630 3320 3630 3320 3320 /* C */ + 3320 3320 3320 3320 3210 /* G */ + 3320 3210 3320 3210 3320 /* T */ +/* NN A ..NN */ + 3320 3180 3320 3080 3320 /* N */ + 3180 3180 3180 3080 3180 /* A */ + 3320 3180 3320 3080 3320 /* C */ + 3080 3080 3080 3080 3080 /* G */ + 3320 3180 3320 3080 3320 /* T */ +/* NN C ..NN */ + 3630 3320 3630 3320 3210 /* N */ + 3320 3320 3320 3320 3210 /* A */ + 3630 3320 3630 3320 3180 /* C */ + 3320 3320 3320 3320 3210 /* G */ + 3210 3210 3050 3210 3050 /* T */ +/* NN G ..NN */ + 3320 3080 3320 3080 3320 /* N */ + 3080 3080 3080 3080 3080 /* A */ + 3320 3080 3320 2730 3320 /* C */ + 3080 3080 2730 2730 2730 /* G */ + 3320 3080 3320 2730 3320 /* T */ +/* NN T ..NN */ + 3320 3320 3050 3320 2870 /* N */ + 3320 3320 2930 3320 2870 /* A */ + 3050 2930 3050 2930 2320 /* C */ + 3320 3320 2930 3320 2870 /* G */ + 2870 2870 2320 2870 2510 /* T */ + +# int22_energies +/* CG A A ..CG */ + 130 150 130 130 /* A */ + 130 150 130 130 /* C */ + 130 150 130 130 /* G */ + 130 150 130 130 /* T */ +/* CG A C ..CG */ + 150 170 150 150 /* A */ + 150 170 150 150 /* C */ + 150 170 150 150 /* G */ + 150 170 150 150 /* T */ +/* CG A G ..CG */ + 130 150 130 130 /* A */ + 130 150 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270 330 270 /* T */ +/* NN G C ..AT */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN G G ..AT */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN G T ..AT */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN T A ..AT */ + 230 270 330 270 /* A */ + 230 270 330 270 /* C */ + 230 270 330 270 /* G */ + 230 270 330 270 /* T */ +/* NN T C ..AT */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN T G ..AT */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN T T ..AT */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN A A ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN A C ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN A G ..TA */ + 200 240 300 240 /* A */ + 200 240 300 240 /* C */ + 200 240 300 240 /* G */ + 200 240 300 240 /* T */ +/* NN A T ..TA */ + 180 220 280 220 /* A */ + 180 220 280 220 /* C */ + 180 220 280 220 /* G */ + 180 220 280 220 /* T */ +/* NN C A ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN C C ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN C G ..TA */ + 200 240 300 240 /* A */ + 200 240 300 240 /* C */ + 200 240 300 240 /* G */ + 200 240 300 240 /* T */ +/* NN C T ..TA */ + 180 220 280 220 /* A */ + 180 220 280 220 /* C */ + 180 220 280 220 /* G */ + 180 220 280 220 /* T */ +/* NN G A ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN G C ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN G G ..TA */ + 200 240 300 240 /* A */ + 200 240 300 240 /* C */ + 200 240 300 240 /* G */ + 200 240 300 240 /* T */ +/* NN G T ..TA */ + 180 220 280 220 /* A */ + 180 220 280 220 /* C */ + 180 220 280 220 /* G */ + 180 220 280 220 /* T */ +/* NN T A ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN T C ..TA */ + 220 260 320 260 /* A */ + 220 260 320 260 /* C */ + 220 260 320 260 /* G */ + 220 260 320 260 /* T */ +/* NN T G ..TA */ + 200 240 300 240 /* A */ + 200 240 300 240 /* C */ + 200 240 300 240 /* G */ + 200 240 300 240 /* T */ +/* NN T T ..TA */ + 180 220 280 220 /* A */ + 180 220 280 220 /* C */ + 180 220 280 220 /* G */ + 180 220 280 220 /* T */ +/* NN A A ..NN */ + 230 270 330 270 /* A */ + 230 270 330 270 /* C */ + 230 270 330 270 /* G */ + 230 270 330 270 /* T */ +/* NN A C ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN A G ..NN */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN A T ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN C A ..NN */ + 230 270 330 270 /* A */ + 230 270 330 270 /* C */ + 230 270 330 270 /* G */ + 230 270 330 270 /* T */ +/* NN C C ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN C G ..NN */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN C T ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN G A ..NN */ + 230 270 330 270 /* A */ + 230 270 330 270 /* C */ + 230 270 330 270 /* G */ + 230 270 330 270 /* T */ +/* NN G C ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN G G ..NN */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN G T ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN T A ..NN */ + 230 270 330 270 /* A */ + 230 270 330 270 /* C */ + 230 270 330 270 /* G */ + 230 270 330 270 /* T */ +/* NN T C ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ +/* NN T G ..NN */ + 330 370 430 370 /* A */ + 330 370 430 370 /* C */ + 330 370 430 370 /* G */ + 330 370 430 370 /* T */ +/* NN T T ..NN */ + 270 310 370 310 /* A */ + 270 310 370 310 /* C */ + 270 310 370 310 /* G */ + 270 310 370 310 /* T */ + +# int22_enthalpies +/* CG A A ..CG */ + -920 -880 -930 -960 /* A */ + -920 -880 -930 -960 /* C */ + -920 -880 -930 -960 /* G */ + -920 -880 -930 -960 /* T */ +/* CG A C ..CG */ + -880 -840 -890 -920 /* A */ + -880 -840 -890 -920 /* C */ + -880 -840 -890 -920 /* G */ + -880 -840 -890 -920 /* T */ +/* CG A G ..CG */ + -930 -890 -940 -970 /* A */ + -930 -890 -940 -970 /* C */ + -930 -890 -940 -970 /* G */ + -930 -890 -940 -970 /* T */ +/* CG A T ..CG */ + -960 -920 -970 -1000 /* A */ + -960 -920 -970 -1000 /* C */ + -960 -920 -970 -1000 /* G */ + -960 -920 -970 -1000 /* T */ +/* CG C A ..CG */ + -920 -880 -930 -960 /* A */ + -920 -880 -930 -960 /* C */ + -920 -880 -930 -960 /* G */ + -920 -880 -930 -960 /* T */ +/* CG C C ..CG */ + -880 -840 -890 -920 /* A */ + -880 -840 -890 -920 /* C */ + -880 -840 -890 -920 /* G */ + -880 -840 -890 -920 /* T */ +/* CG C G ..CG */ + -930 -890 -940 -970 /* A */ + -930 -890 -940 -970 /* C */ + -930 -890 -940 -970 /* G */ + -930 -890 -940 -970 /* T */ +/* CG C T ..CG */ + -960 -920 -970 -1000 /* A */ + -960 -920 -970 -1000 /* C */ + -960 -920 -970 -1000 /* G */ + -960 -920 -970 -1000 /* T */ +/* CG G A ..CG */ + -920 -880 -930 -960 /* A */ + -920 -880 -930 -960 /* C */ + -920 -880 -930 -960 /* G */ + -920 -880 -930 -960 /* T */ +/* CG G C ..CG */ + -880 -840 -890 -920 /* A */ + -880 -840 -890 -920 /* C */ + -880 -840 -890 -920 /* G */ + -880 -840 -890 -920 /* T */ +/* CG G G ..CG */ + -930 -890 -940 -970 /* A */ + -930 -890 -940 -970 /* C */ + -930 -890 -940 -970 /* G */ + -930 -890 -940 -970 /* T */ +/* CG G T ..CG */ + -960 -920 -970 -1000 /* A */ + -960 -920 -970 -1000 /* C */ + -960 -920 -970 -1000 /* G */ + -960 -920 -970 -1000 /* T */ +/* CG T A ..CG */ + -920 -880 -930 -960 /* A */ + -920 -880 -930 -960 /* C */ + -920 -880 -930 -960 /* G */ + -920 -880 -930 -960 /* T */ +/* CG T C ..CG */ + -880 -840 -890 -920 /* A */ + -880 -840 -890 -920 /* C */ + -880 -840 -890 -920 /* G */ + -880 -840 -890 -920 /* T */ +/* CG T G ..CG */ + -930 -890 -940 -970 /* A */ + -930 -890 -940 -970 /* C */ + -930 -890 -940 -970 /* G */ + -930 -890 -940 -970 /* T */ +/* CG T T ..CG */ + -960 -920 -970 -1000 /* A */ + -960 -920 -970 -1000 /* C */ + -960 -920 -970 -1000 /* G */ + -960 -920 -970 -1000 /* T */ +/* CG A A ..GC */ + -1080 -1040 -1090 -1120 /* A */ + -1080 -1040 -1090 -1120 /* C */ + -1080 -1040 -1090 -1120 /* G */ + -1080 -1040 -1090 -1120 /* T */ +/* CG A C ..GC */ + -790 -750 -800 -830 /* A */ + -790 -750 -800 -830 /* C */ + -790 -750 -800 -830 /* G */ + -790 -750 -800 -830 /* T */ +/* CG A G ..GC */ + -970 -930 -980 -1010 /* A */ + -970 -930 -980 -1010 /* C */ + -970 -930 -980 -1010 /* G */ + -970 -930 -980 -1010 /* T */ +/* CG A T ..GC */ + -550 -510 -560 -590 /* A */ + -550 -510 -560 -590 /* C */ + -550 -510 -560 -590 /* G */ + -550 -510 -560 -590 /* T */ +/* CG C A ..GC */ + -1080 -1040 -1090 -1120 /* A */ + -1080 -1040 -1090 -1120 /* C */ + -1080 -1040 -1090 -1120 /* G */ + -1080 -1040 -1090 -1120 /* T */ +/* CG C C ..GC */ + -790 -750 -800 -830 /* A */ + -790 -750 -800 -830 /* C */ + -790 -750 -800 -830 /* G */ + -790 -750 -800 -830 /* T */ +/* CG C G ..GC */ + -970 -930 -980 -1010 /* A */ + -970 -930 -980 -1010 /* C */ + -970 -930 -980 -1010 /* G */ + -970 -930 -980 -1010 /* T */ +/* CG C T ..GC */ + -550 -510 -560 -590 /* A */ + -550 -510 -560 -590 /* C */ + -550 -510 -560 -590 /* G */ + -550 -510 -560 -590 /* T */ +/* CG G A ..GC */ + -1080 -1040 -1090 -1120 /* A */ + -1080 -1040 -1090 -1120 /* C */ + -1080 -1040 -1090 -1120 /* G */ + -1080 -1040 -1090 -1120 /* T */ +/* CG G C ..GC */ + -790 -750 -800 -830 /* A */ + -790 -750 -800 -830 /* C */ + -790 -750 -800 -830 /* G */ + -790 -750 -800 -830 /* T */ +/* CG G G ..GC */ + -970 -930 -980 -1010 /* A */ + -970 -930 -980 -1010 /* C */ + -970 -930 -980 -1010 /* G */ + -970 -930 -980 -1010 /* T */ +/* CG G T ..GC */ + -550 -510 -560 -590 /* A */ + -550 -510 -560 -590 /* C */ + -550 -510 -560 -590 /* G */ + -550 -510 -560 -590 /* T */ +/* CG T A ..GC */ + -1080 -1040 -1090 -1120 /* A */ + -1080 -1040 -1090 -1120 /* C */ + -1080 -1040 -1090 -1120 /* G */ + -1080 -1040 -1090 -1120 /* T */ +/* CG T C ..GC */ + -790 -750 -800 -830 /* A */ + -790 -750 -800 -830 /* C */ + -790 -750 -800 -830 /* G */ + -790 -750 -800 -830 /* T */ +/* CG T G ..GC */ + -970 -930 -980 -1010 /* A */ + -970 -930 -980 -1010 /* C */ + -970 -930 -980 -1010 /* G */ + -970 -930 -980 -1010 /* T */ +/* CG T T ..GC */ + -550 -510 -560 -590 /* A */ + -550 -510 -560 -590 /* C */ + -550 -510 -560 -590 /* G */ + -550 -510 -560 -590 /* T */ +/* CG A A ..GT */ + -760 -720 -770 -800 /* A */ + -760 -720 -770 -800 /* C */ + -760 -720 -770 -800 /* G */ + -760 -720 -770 -800 /* T */ +/* CG A C ..GT */ + -470 -430 -480 -510 /* A */ + -470 -430 -480 -510 /* C */ + -470 -430 -480 -510 /* G */ + -470 -430 -480 -510 /* T */ +/* CG A G ..GT */ + -650 -610 -660 -690 /* A */ + -650 -610 -660 -690 /* C */ + -650 -610 -660 -690 /* G */ + -650 -610 -660 -690 /* T */ +/* CG A T ..GT */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG C A ..GT */ + -760 -720 -770 -800 /* A */ + -760 -720 -770 -800 /* C */ + -760 -720 -770 -800 /* G */ + -760 -720 -770 -800 /* T */ +/* CG C C ..GT */ + -470 -430 -480 -510 /* A */ + -470 -430 -480 -510 /* C */ + -470 -430 -480 -510 /* G */ + -470 -430 -480 -510 /* T */ +/* CG C G ..GT */ + -650 -610 -660 -690 /* A */ + -650 -610 -660 -690 /* C */ + -650 -610 -660 -690 /* G */ + -650 -610 -660 -690 /* T */ +/* CG C T ..GT */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG G A ..GT */ + -760 -720 -770 -800 /* A */ + -760 -720 -770 -800 /* C */ + -760 -720 -770 -800 /* G */ + -760 -720 -770 -800 /* T */ +/* CG G C ..GT */ + -470 -430 -480 -510 /* A */ + -470 -430 -480 -510 /* C */ + -470 -430 -480 -510 /* G */ + -470 -430 -480 -510 /* T */ +/* CG G G ..GT */ + -650 -610 -660 -690 /* A */ + -650 -610 -660 -690 /* C */ + -650 -610 -660 -690 /* G */ + -650 -610 -660 -690 /* T */ +/* CG G T ..GT */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG T A ..GT */ + -760 -720 -770 -800 /* A */ + -760 -720 -770 -800 /* C */ + -760 -720 -770 -800 /* G */ + -760 -720 -770 -800 /* T */ +/* CG T C ..GT */ + -470 -430 -480 -510 /* A */ + -470 -430 -480 -510 /* C */ + -470 -430 -480 -510 /* G */ + -470 -430 -480 -510 /* T */ +/* CG T G ..GT */ + -650 -610 -660 -690 /* A */ + -650 -610 -660 -690 /* C */ + -650 -610 -660 -690 /* G */ + -650 -610 -660 -690 /* T */ +/* CG T T ..GT */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG A A ..TG */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG A C ..TG */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG A G ..TG */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG A T ..TG */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG C A ..TG */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG C C ..TG */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG C G ..TG */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG C T ..TG */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG G A ..TG */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG G C ..TG */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG G G ..TG */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG G T ..TG */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG T A ..TG */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG T C ..TG */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG T G ..TG */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG T T ..TG */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG A A ..AT */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG A C ..AT */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG A G ..AT */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG A T ..AT */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG C A ..AT */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG C C ..AT */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG C G ..AT */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG C T ..AT */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG G A ..AT */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG G C ..AT */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG G G ..AT */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG G T ..AT */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG T A ..AT */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG T C ..AT */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG T G ..AT */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG T T ..AT */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG A A ..TA */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG A C ..TA */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG A G ..TA */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG A T ..TA */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG C A ..TA */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG C C ..TA */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG C G ..TA */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG C T ..TA */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG G A ..TA */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG G C ..TA */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG G G ..TA */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG G T ..TA */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG T A ..TA */ + -230 -190 -240 -270 /* A */ + -230 -190 -240 -270 /* C */ + -230 -190 -240 -270 /* G */ + -230 -190 -240 -270 /* T */ +/* CG T C ..TA */ + -200 -160 -210 -240 /* A */ + -200 -160 -210 -240 /* C */ + -200 -160 -210 -240 /* G */ + -200 -160 -210 -240 /* T */ +/* CG T G ..TA */ + -390 -350 -400 -430 /* A */ + -390 -350 -400 -430 /* C */ + -390 -350 -400 -430 /* G */ + -390 -350 -400 -430 /* T */ +/* CG T T ..TA */ + -1040 -1000 -1050 -1080 /* A */ + -1040 -1000 -1050 -1080 /* C */ + -1040 -1000 -1050 -1080 /* G */ + -1040 -1000 -1050 -1080 /* T */ +/* CG A A ..NN */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG A C ..NN */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG A G ..NN */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG A T ..NN */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG C A ..NN */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG C C ..NN */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG C G ..NN */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG C T ..NN */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG G A ..NN */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG G C ..NN */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG G G ..NN */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG G T ..NN */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* CG T A ..NN */ + -60 -20 -70 -100 /* A */ + -60 -20 -70 -100 /* C */ + -60 -20 -70 -100 /* G */ + -60 -20 -70 -100 /* T */ +/* CG T C ..NN */ + 60 100 50 20 /* A */ + 60 100 50 20 /* C */ + 60 100 50 20 /* G */ + 60 100 50 20 /* T */ +/* CG T G ..NN */ + 10 50 0 -30 /* A */ + 10 50 0 -30 /* C */ + 10 50 0 -30 /* G */ + 10 50 0 -30 /* T */ +/* CG T T ..NN */ + -30 10 -40 -70 /* A */ + -30 10 -40 -70 /* C */ + -30 10 -40 -70 /* G */ + -30 10 -40 -70 /* T */ +/* GC A A ..CG */ + -1080 -790 -970 -550 /* A */ + -1080 -790 -970 -550 /* C */ + -1080 -790 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-60 /* C */ + 750 780 590 -60 /* G */ + 750 780 590 -60 /* T */ +/* TG C G ..NN */ + 700 730 540 -110 /* A */ + 700 730 540 -110 /* C */ + 700 730 540 -110 /* G */ + 700 730 540 -110 /* T */ +/* TG C T ..NN */ + 660 690 500 -150 /* A */ + 660 690 500 -150 /* C */ + 660 690 500 -150 /* G */ + 660 690 500 -150 /* T */ +/* TG G A ..NN */ + 630 660 470 -180 /* A */ + 630 660 470 -180 /* C */ + 630 660 470 -180 /* G */ + 630 660 470 -180 /* T */ +/* TG G C ..NN */ + 750 780 590 -60 /* A */ + 750 780 590 -60 /* C */ + 750 780 590 -60 /* G */ + 750 780 590 -60 /* T */ +/* TG G G ..NN */ + 700 730 540 -110 /* A */ + 700 730 540 -110 /* C */ + 700 730 540 -110 /* G */ + 700 730 540 -110 /* T */ +/* TG G T ..NN */ + 660 690 500 -150 /* A */ + 660 690 500 -150 /* C */ + 660 690 500 -150 /* G */ + 660 690 500 -150 /* T */ +/* TG T A ..NN */ + 630 660 470 -180 /* A */ + 630 660 470 -180 /* C */ + 630 660 470 -180 /* G */ + 630 660 470 -180 /* T */ +/* TG T C ..NN */ + 750 780 590 -60 /* A */ + 750 780 590 -60 /* C */ + 750 780 590 -60 /* G */ + 750 780 590 -60 /* T */ +/* TG T G ..NN */ + 700 730 540 -110 /* A */ + 700 730 540 -110 /* C */ + 700 730 540 -110 /* G */ + 700 730 540 -110 /* T */ +/* TG T T ..NN */ + 660 690 500 -150 /* A */ + 660 690 500 -150 /* C */ + 660 690 500 -150 /* G */ + 660 690 500 -150 /* T */ +/* AT A A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* AT A C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* AT A G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* AT A T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* AT C A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* AT C C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* AT C G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* AT C T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* AT G A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* AT G C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* AT G G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* AT G T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* AT T A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* AT T C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* AT T G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* AT T T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* AT A A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* AT A C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* AT A G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* AT A T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* AT C A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* AT C C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* AT C G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 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-110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* AT T T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* AT A A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* AT A C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* AT A G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* AT A T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT C A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* AT C C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* AT C G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* AT C T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT G A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* AT G C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* AT G G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* AT G T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT T A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* AT T C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* AT T G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* AT T T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT A A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT A C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* AT A G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* AT A T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* AT C A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT C C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* AT C G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* AT C T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* AT G A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT G C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* AT G G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* AT G T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* AT T A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* AT T C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* AT T G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* AT T T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* AT A A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* AT A C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* AT A G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* AT A T ..AT */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* AT C A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* AT C C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* AT C G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C 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170 -20 -670 /* A */ + 140 170 -20 -670 /* C */ + 140 170 -20 -670 /* G */ + 140 170 -20 -670 /* T */ +/* TA T A ..GC */ + -390 -360 -550 -1200 /* A */ + -390 -360 -550 -1200 /* C */ + -390 -360 -550 -1200 /* G */ + -390 -360 -550 -1200 /* T */ +/* TA T C ..GC */ + -100 -70 -260 -910 /* A */ + -100 -70 -260 -910 /* C */ + -100 -70 -260 -910 /* G */ + -100 -70 -260 -910 /* T */ +/* TA T G ..GC */ + -280 -250 -440 -1090 /* A */ + -280 -250 -440 -1090 /* C */ + -280 -250 -440 -1090 /* G */ + -280 -250 -440 -1090 /* T */ +/* TA T T ..GC */ + 140 170 -20 -670 /* A */ + 140 170 -20 -670 /* C */ + 140 170 -20 -670 /* G */ + 140 170 -20 -670 /* T */ +/* TA A A ..GT */ + -70 -40 -230 -880 /* A */ + -70 -40 -230 -880 /* C */ + -70 -40 -230 -880 /* G */ + -70 -40 -230 -880 /* T */ +/* TA A C ..GT */ + 220 250 60 -590 /* A */ + 220 250 60 -590 /* C */ + 220 250 60 -590 /* G */ + 220 250 60 -590 /* T */ +/* TA A G ..GT */ + 40 70 -120 -770 /* A */ + 40 70 -120 -770 /* C */ + 40 70 -120 -770 /* G */ 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/* T */ +/* NN A C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* NN A G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* NN A T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* NN C A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* NN C C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* NN C G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* NN C T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* NN G A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* NN G C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* NN G G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* NN G T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* NN T A ..CG */ + -60 60 10 -30 /* A */ + -60 60 10 -30 /* C */ + -60 60 10 -30 /* G */ + -60 60 10 -30 /* T */ +/* NN T C ..CG */ + -20 100 50 10 /* A */ + -20 100 50 10 /* C */ + -20 100 50 10 /* G */ + -20 100 50 10 /* T */ +/* NN T G ..CG */ + -70 50 0 -40 /* A */ + -70 50 0 -40 /* C */ + -70 50 0 -40 /* G */ + -70 50 0 -40 /* T */ +/* NN T T ..CG */ + -100 20 -30 -70 /* A */ + -100 20 -30 -70 /* C */ + -100 20 -30 -70 /* G */ + -100 20 -30 -70 /* T */ +/* NN A A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* NN A C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* NN A G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* NN A T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* NN C A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* NN C C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* NN C G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* NN C T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* NN G A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* NN G C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* NN G G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* NN G T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* NN T A ..GC */ + -220 -100 -150 -190 /* A */ + -220 -100 -150 -190 /* C */ + -220 -100 -150 -190 /* G */ + -220 -100 -150 -190 /* T */ +/* NN T C ..GC */ + 70 190 140 100 /* A */ + 70 190 140 100 /* C */ + 70 190 140 100 /* G */ + 70 190 140 100 /* T */ +/* NN T G ..GC */ + -110 10 -40 -80 /* A */ + -110 10 -40 -80 /* C */ + -110 10 -40 -80 /* G */ + -110 10 -40 -80 /* T */ +/* NN T T ..GC */ + 310 430 380 340 /* A */ + 310 430 380 340 /* C */ + 310 430 380 340 /* G */ + 310 430 380 340 /* T */ +/* NN A A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* NN A C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* NN A G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* NN A T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN C A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* NN C C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* NN C G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* NN C T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN G A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* NN G C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* NN G G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* NN G T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN T A ..GT */ + 100 220 170 130 /* A */ + 100 220 170 130 /* C */ + 100 220 170 130 /* G */ + 100 220 170 130 /* T */ +/* NN T C ..GT */ + 390 510 460 420 /* A */ + 390 510 460 420 /* C */ + 390 510 460 420 /* G */ + 390 510 460 420 /* T */ +/* NN T G ..GT */ + 210 330 280 240 /* A */ + 210 330 280 240 /* C */ + 210 330 280 240 /* G */ + 210 330 280 240 /* T */ +/* NN T T ..GT */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN A A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN A C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN A G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN A T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN C A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN C C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN C G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN C T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN G A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN G C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN G G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN G T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN T A ..TG */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN T C ..TG */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN T G ..TG */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN T T ..TG */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN A A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN A C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN A G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN A T ..AT */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN C A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN C C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN C G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN C T ..AT */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN G A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN G C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN G G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN G T ..AT */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN T A ..AT */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN T C ..AT */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN T G ..AT */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN T T ..AT */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN A A ..TA */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN A C ..TA */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN A G ..TA */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN A T ..TA */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN C A ..TA */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN C C ..TA */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN C G ..TA */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN C T ..TA */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN G A ..TA */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN G C ..TA */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN G G ..TA */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN G T ..TA */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN T A ..TA */ + 630 750 700 660 /* A */ + 630 750 700 660 /* C */ + 630 750 700 660 /* G */ + 630 750 700 660 /* T */ +/* NN T C ..TA */ + 660 780 730 690 /* A */ + 660 780 730 690 /* C */ + 660 780 730 690 /* G */ + 660 780 730 690 /* T */ +/* NN T G ..TA */ + 470 590 540 500 /* A */ + 470 590 540 500 /* C */ + 470 590 540 500 /* G */ + 470 590 540 500 /* T */ +/* NN T T ..TA */ + -180 -60 -110 -150 /* A */ + -180 -60 -110 -150 /* C */ + -180 -60 -110 -150 /* G */ + -180 -60 -110 -150 /* T */ +/* NN A A ..NN */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN A C ..NN */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN A G ..NN */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN A T ..NN */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN C A ..NN */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN C C ..NN */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN C G ..NN */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN C T ..NN */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN G A ..NN */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN G C ..NN */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN G G ..NN */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN G T ..NN */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ +/* NN T A ..NN */ + 800 920 870 830 /* A */ + 800 920 870 830 /* C */ + 800 920 870 830 /* G */ + 800 920 870 830 /* T */ +/* NN T C ..NN */ + 920 1040 990 950 /* A */ + 920 1040 990 950 /* C */ + 920 1040 990 950 /* G */ + 920 1040 990 950 /* T */ +/* NN T G ..NN */ + 870 990 940 900 /* A */ + 870 990 940 900 /* C */ + 870 990 940 900 /* G */ + 870 990 940 900 /* T */ +/* NN T T ..NN */ + 830 950 900 860 /* A */ + 830 950 900 860 /* C */ + 830 950 900 860 /* G */ + 830 950 900 860 /* T */ + +# hairpin + INF INF INF 340 340 350 420 420 420 430 + 440 450 460 470 480 500 510 520 530 540 + 550 560 570 580 590 600 610 620 630 640 + 650 + +# bulge + INF 380 280 320 350 380 400 420 430 440 + 450 460 470 480 490 500 500 510 520 520 + 530 530 540 540 550 550 560 560 560 570 + 570 + +# internal_loop + INF INF INF INF 250 270 290 310 320 340 + 350 360 370 380 390 390 400 410 410 420 + 420 430 430 440 440 450 450 460 460 460 + 470 + +# ML_params +/* the numbers below are really meant to be used with co-axial stacking */ +/* without the penalty is certainly too large */ +/* F = cu*n_unpaired + cc + ci*loop_degree (+TermAU) */ +/* cu cc ci TerminalAU DuplexInit*/ + 0 1280 -60 20 210 + +# NINIO +/* Ninio = MIN(max, m*|n1-n2| */ +/* m max */ + 60 300 + +# Tetraloops + GGUCAC -80 /* 160 */ + GGCUAC -70 /* 170 */ + GGAAAC 0 /* 240 */ + CUUUUG -60 /* 220 */ + CAAAAG 0 /* 280 */ + AUUUUU -380 /* 10 */ + AAAAAU -70 /* 280 */ + UUAAUA -120 /* 180 */ + GAAAAC -60 /* 180 */ + GUAAUC -80 /* 180 */ + CUUUUG -200 /* 80 */ + GGTCAC -80 /* 160 */ + GGCTAC -70 /* 170 */ + GGAAAC 0 /* 240 */ + CTTTTG -60 /* 220 */ + CAAAAG 0 /* 280 */ + ATTTTT -380 /* 10 */ + AAAAAT -70 /* 280 */ + TTAATA -120 /* 180 */ + GAAAAC -60 /* 180 */ + GTAATC -80 /* 180 */ + CTTTTG -200 /* 80 */ + CAAAAG -90 /* 190 */ + CAAAAG -90 /* 190 */ + +# Triloops + CGCAG -390 /* -50 */ + CUUUG -290 /* 50 */ + AUAAU 80 /* 460 */ + CGCAG -390 /* -50 */ + CTTTG -290 /* 50 */ + ATAAT 80 /* 460 */ + +# mismatch_hairpin +/* CG.. */ + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 +/* GC.. */ + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 +/* GT.. */ + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 +/* TG.. */ + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 +/* AT.. */ + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 +/* TA.. */ + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 +/* NN.. */ + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + +# mismatch_interior +/* CG.. */ + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 + -40 -60 -40 -60 -60 +/* GC.. */ + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 + -50 -100 -50 -60 -80 +/* GT.. */ + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 + -30 -80 -30 -40 -60 +/* TG.. */ + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 +/* AT.. */ + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 +/* TA.. */ + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 + -20 -20 -20 -40 -60 +/* NN.. */ + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + 90 -10 30 90 30 + +# mismatch_enthalpies +/* CG.. */ + -420 -460 -420 -470 -500 + -420 -460 -420 -470 -500 + -420 -460 -420 -470 -500 + -420 -460 -420 -470 -500 + -420 -460 -420 -470 -500 +/* GC.. */ + -90 -620 -330 -510 -90 + -90 -620 -330 -510 -90 + -90 -620 -330 -510 -90 + -90 -620 -330 -510 -90 + -90 -620 -330 -510 -90 +/* GT.. */ + 230 -300 -10 -190 230 + 230 -300 -10 -190 230 + 230 -300 -10 -190 230 + 230 -300 -10 -190 230 + 230 -300 -10 -190 230 +/* TG.. */ + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 +/* AT.. */ + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 +/* TA.. */ + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 + 230 230 170 70 -580 +/* NN.. */ + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 + 520 400 520 470 430 \ No newline at end of file diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/README b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/README new file mode 100755 index 00000000..95fa6ccc --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/README @@ -0,0 +1,83 @@ +This is Version 1.6 of the Vienna RNA Package. +This is a pre-release possibly containing more bugs than usual! +------------------------------------------------ +See the NEWS and Changelog files for differences to previous versions. + +The Vienna RNA packages consists of a few stand alone programs and a +library that you can link your own programs with. The package allows you to + +- predict minimum free energy secondary structures +- calculate the partition function for the ensemble of structures +- calculate suboptimal structures in a given energy range +- predict consensus secondary sctructures from a multiple sequence alignment +- predict melting curves +- search for sequences folding into a given structure +- compare two secondary structures + +The package includes a Perl5 module that gives access to almost all +functions of the C library from Perl. + +There is also a set of programs for analysing sequence and distance +data using split decomposition, statistical geometry, and cluster methods. +They are not maintained any more and not built by default. + +See the NEWS and Changelog files for changes between versions. + +Please read the copyright notice in the file COPYING! + +The package should be easily portable. It is known to compile without +modifications at least under +SunOS 5.x, IRIX 5.x and 6.x, linux, and windows with the CygWin environment. +Other UN*X flavours should present no problems. +You need a compiler that understands ANSI C. See the INSTALL file for details. + +The following executables are provided: +RNAfold predict secondary structures +RNAsubopt calulate suboptimal structures in a given energy range +RNAalifold predict a consensus structure for a set of aligned sequences +RNAcofold calculate the hybrid structure of two RNA molecules +RNAduplex predict possible hybridization sites for two RNAs +RNAeval evaluate energy for given sequence and structure +RNALfold calculate locally stable RNA secondary structures +RNAheat calculate melting curves +RNAdistance compare secondary structures +RNApdist compare ensembles of secondary structures +RNAinverse find sequences folding into given structures +AnalyseSeqs analyse sequence data +AnalyseDists analyse distance matrices + +A couple of useful utililities can be found in the Utils directory. + +All executables read from stdin and write to stdout and use command line +switches rather than menus to be easily usable in pipes. + +For more detailed information see the man pages. + +We have included a patched version of D.G. Gilbert's readseq program +for those who often process sequence files from databanks. See the +the documentation in that directory for details. + + +Versions since 1.4 feature new energy parameters as described in Mathews +et.al, JMB, 1999. For backward compatibility a parameter file with the +version 1.3 parameter set (as described in Walter et.al (1994)) can be +found in the file vienna13.par. The standard energy set is compiled in, but +can also be found in the file default.par. Note that only free energies at +37C are new. Temperature dependencies are still derived from the old +parameter set. +The code very rarely uses static arrays, and all programs should work for +sequences up to a length of 32700 (if you have huge amounts of memory that +is). + +If you're a commercial user and find these programs useful, please consider +supporting further developments with a donation. + +The most recent source code and documentation should always be available on +the web at +http://www.tbi.univie.ac.at/~ivo/RNA/ + +We need your feedback! Send your comments, suggestions, and questions to +rna@tbi.univie.ac.at + +Ivo Hofacker, Autumn 2002 + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/AUTHORS b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/AUTHORS new file mode 100755 index 00000000..f302054d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/AUTHORS @@ -0,0 +1 @@ +Matthias Hoechsmann (mhoechsm@techfak.uni-bielefeld.de) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/COPYING b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/COPYING new file mode 100755 index 00000000..ec71421a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/COPYING @@ -0,0 +1,34 @@ + Disclaimer and Copyright + +The programs and source code of RNAforester are free +software. They are distributed in the hope that they will be useful +but WITHOUT ANY WARRANTY; without even the implied warranty of +MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +Permission is granted for research, educational, and commercial use +and modification so long as 1) the package and any derived works are not +redistributed for any fee, other than media costs, 2) proper credit is +given to the authors. + +If you want to include this software in a commercial product, please contact +the authors. + +The include files "fold_vars.h" and "part_func.h" "utils.h" are slightly modified to be compatible +with the g++ compiler and distributed with this package. Note that these files have their own +copyrights attached. + +The code for computing a maximum wheigted matching was written by Ed Rothberg +and implements H. Gabow's N-cubed weighted matching algorithm, +as described in his Ph.D. thesis +"Implementation of Algorithms for Maximum Matching on Nonbipartite Graphs" +Stanford University, 1973. +(refer to http://elib.zib.de/pub/Packages/mathprog/matching/weighted/) + +The prediction of structures utilizes functions from the Vienna +RNA library, originally described in: +Fast Folding and Comparison of RNA Secondary Structures, +Ivo L. Hofacker, Walter Fontana, Peter F. Stadler, L. Sebastian Bonhoeffer, Manfred Tacker, and Peter Schuster +Appeared in: Monatsh.Chem. 125: 167-188 (1994). + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/ChangeLog b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/ChangeLog new file mode 100755 index 00000000..70cac168 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/ChangeLog @@ -0,0 +1,7 @@ +1.4.1 2004.06.29 + - new option -s computes small-in-large similarity. + - bugfix: strcuture alignment was shown although option -p was used. + +ChangeLog is starting with version 1.4. All earlier versions were experimental. + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/INSTALL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/INSTALL new file mode 100755 index 00000000..12a4f291 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/INSTALL @@ -0,0 +1,72 @@ +Installation: + +This package uses GNU autoconf generated configure scripts, see the +file INSTALL.configure for generic configure documentation. + +Requirements: +---------- + +You must have the g2 - graphic library V0.49a (C) 1999 Lj. Milanovic, H. Wagner +installed on your system. If not the g2 graphics library +is ditributed with RNAforester by the file g2-0.49a.tar.gz. + +If g2 is installed usually you'll just have to type: + ./configure + make +and (as root) + make install + +The Vienna RNA lib (libRNA) (C) I. Hofacker must be installed on your system. +Refer to http://www.tbi.univie.ac.at/~ivo/RNA/ for download and further +instructions. + +Quickstart for users that do not have administrator rights +---------------------------------------------------------- + +Say your home directory is /home/user. +If the g2 library is not installed on your system you'll have to type: + +tar xvzf g2-0.49a.tar.gz +cd g2-0.49a +./configure --prefix=/home/user +make +make install +cd .. + +Make sure the Vienna RNA package is installed on your system. + +To install RNAforester type: + +./configure --prefix=/home/user +make +make install + +If the includes files of the g2 library cannot be found you can add +the path including the headers as follows: +CPPFLAGS=-I/home/user/include ./configure --prefix=/home/user +(of course, your include path can differ) + +Installation Paths: +------------- +The main programs, library and man are +installed in the usual places by default +(i.e. /usr/local/{bin,lib,man}). + +All these locations can be changed by calling ./configure with +appropriate options. + + +Microsoft Visual C++ +----------------------- + +RNAforester uses the getline function of STL. 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It is known to compile without +modifications at least under SunOS 8.x, and linux. +Other UN*X flavours should present no problems. +You need a compiler that understands standard C++. +See the INSTALL file for details. + +For more details about RNAforester information see the man page. + +If you're a commercial user and find these programs useful, please consider +supporting further developments with a donation. + +The most recent source code and documentation should always be available on +the web at http://bibiserv.techfak.uni-bielefeld.de/rnaforester + +I appreciate any feedback! Send your comments, suggestions, and questions to +mhoechsm@techfak.uni-bielefeld.de + +Matthias Hoechsmann, June 2004 + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/TODO b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/TODO new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/aclocal.m4 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/aclocal.m4 new file mode 100755 index 00000000..74de4a19 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/aclocal.m4 @@ -0,0 +1,862 @@ +# generated automatically by aclocal 1.9.5 -*- Autoconf -*- + +# Copyright (C) 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, +# 2005 Free Software Foundation, Inc. +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + +# Copyright (C) 2002, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# AM_AUTOMAKE_VERSION(VERSION) +# ---------------------------- +# Automake X.Y traces this macro to ensure aclocal.m4 has been +# generated from the m4 files accompanying Automake X.Y. +AC_DEFUN([AM_AUTOMAKE_VERSION], [am__api_version="1.9"]) + +# AM_SET_CURRENT_AUTOMAKE_VERSION +# ------------------------------- +# Call AM_AUTOMAKE_VERSION so it can be traced. +# This function is AC_REQUIREd by AC_INIT_AUTOMAKE. +AC_DEFUN([AM_SET_CURRENT_AUTOMAKE_VERSION], + [AM_AUTOMAKE_VERSION([1.9.5])]) + +# AM_AUX_DIR_EXPAND -*- Autoconf -*- + +# Copyright (C) 2001, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# For projects using AC_CONFIG_AUX_DIR([foo]), Autoconf sets +# $ac_aux_dir to `$srcdir/foo'. 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We just wanted to have am__tar + # and am__untar set. + test -n "${am_cv_prog_tar_$1}" && break + + # tar/untar a dummy directory, and stop if the command works + rm -rf conftest.dir + mkdir conftest.dir + echo GrepMe > conftest.dir/file + AM_RUN_LOG([tardir=conftest.dir && eval $am__tar_ >conftest.tar]) + rm -rf conftest.dir + if test -s conftest.tar; then + AM_RUN_LOG([$am__untar /dev/null 2>&1 && break + fi +done +rm -rf conftest.dir + +AC_CACHE_VAL([am_cv_prog_tar_$1], [am_cv_prog_tar_$1=$_am_tool]) +AC_MSG_RESULT([$am_cv_prog_tar_$1])]) +AC_SUBST([am__tar]) +AC_SUBST([am__untar]) +]) # _AM_PROG_TAR + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.guess b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.guess new file mode 100755 index 00000000..fd30ab03 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.guess @@ -0,0 +1,1354 @@ +#! /bin/sh +# Attempt to guess a canonical system name. +# Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, +# 2000, 2001, 2002 Free Software Foundation, Inc. + +timestamp='2002-07-23' + +# This file is free software; you can redistribute it and/or modify it +# under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2 of the License, or +# (at your option) any later version. +# +# This program is distributed in the hope that it will be useful, but +# WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +# General Public License for more details. +# +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA. +# +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Originally written by Per Bothner . +# Please send patches to . Submit a context +# diff and a properly formatted ChangeLog entry. +# +# This script attempts to guess a canonical system name similar to +# config.sub. If it succeeds, it prints the system name on stdout, and +# exits with 0. Otherwise, it exits with 1. +# +# The plan is that this can be called by configure scripts if you +# don't specify an explicit build system type. + +me=`echo "$0" | sed -e 's,.*/,,'` + +usage="\ +Usage: $0 [OPTION] + +Output the configuration name of the system \`$me' is run on. + +Operation modes: + -h, --help print this help, then exit + -t, --time-stamp print date of last modification, then exit + -v, --version print version number, then exit + +Report bugs and patches to ." + +version="\ +GNU config.guess ($timestamp) + +Originally written by Per Bothner. +Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001 +Free Software Foundation, Inc. + +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE." + +help=" +Try \`$me --help' for more information." + +# Parse command line +while test $# -gt 0 ; do + case $1 in + --time-stamp | --time* | -t ) + echo "$timestamp" ; exit 0 ;; + --version | -v ) + echo "$version" ; exit 0 ;; + --help | --h* | -h ) + echo "$usage"; exit 0 ;; + -- ) # Stop option processing + shift; break ;; + - ) # Use stdin as input. + break ;; + -* ) + echo "$me: invalid option $1$help" >&2 + exit 1 ;; + * ) + break ;; + esac +done + +if test $# != 0; then + echo "$me: too many arguments$help" >&2 + exit 1 +fi + +trap 'exit 1' 1 2 15 + +# CC_FOR_BUILD -- compiler used by this script. Note that the use of a +# compiler to aid in system detection is discouraged as it requires +# temporary files to be created and, as you can see below, it is a +# headache to deal with in a portable fashion. + +# Historically, `CC_FOR_BUILD' used to be named `HOST_CC'. We still +# use `HOST_CC' if defined, but it is deprecated. + +# This shell variable is my proudest work .. or something. --bje + +set_cc_for_build='tmpdir=${TMPDIR-/tmp}/config-guess-$$ ; +(old=`umask` && umask 077 && mkdir $tmpdir && umask $old && unset old) + || (echo "$me: cannot create $tmpdir" >&2 && exit 1) ; +dummy=$tmpdir/dummy ; +files="$dummy.c $dummy.o $dummy.rel $dummy" ; +trap '"'"'rm -f $files; rmdir $tmpdir; exit 1'"'"' 1 2 15 ; +case $CC_FOR_BUILD,$HOST_CC,$CC in + ,,) echo "int x;" > $dummy.c ; + for c in cc gcc c89 c99 ; do + if ($c $dummy.c -c -o $dummy.o) >/dev/null 2>&1 ; then + CC_FOR_BUILD="$c"; break ; + fi ; + done ; + rm -f $files ; + if test x"$CC_FOR_BUILD" = x ; then + CC_FOR_BUILD=no_compiler_found ; + fi + ;; + ,,*) CC_FOR_BUILD=$CC ;; + ,*,*) CC_FOR_BUILD=$HOST_CC ;; +esac ; +unset files' + +# This is needed to find uname on a Pyramid OSx when run in the BSD universe. +# (ghazi@noc.rutgers.edu 1994-08-24) +if (test -f /.attbin/uname) >/dev/null 2>&1 ; then + PATH=$PATH:/.attbin ; export PATH +fi + +UNAME_MACHINE=`(uname -m) 2>/dev/null` || UNAME_MACHINE=unknown +UNAME_RELEASE=`(uname -r) 2>/dev/null` || UNAME_RELEASE=unknown +UNAME_SYSTEM=`(uname -s) 2>/dev/null` || UNAME_SYSTEM=unknown +UNAME_VERSION=`(uname -v) 2>/dev/null` || UNAME_VERSION=unknown + +# Note: order is significant - the case branches are not exclusive. + +case "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" in + *:NetBSD:*:*) + # NetBSD (nbsd) targets should (where applicable) match one or + # more of the tupples: *-*-netbsdelf*, *-*-netbsdaout*, + # *-*-netbsdecoff* and *-*-netbsd*. For targets that recently + # switched to ELF, *-*-netbsd* would select the old + # object file format. This provides both forward + # compatibility and a consistent mechanism for selecting the + # object file format. + # + # Note: NetBSD doesn't particularly care about the vendor + # portion of the name. We always set it to "unknown". + sysctl="sysctl -n hw.machine_arch" + UNAME_MACHINE_ARCH=`(/sbin/$sysctl 2>/dev/null || \ + /usr/sbin/$sysctl 2>/dev/null || echo unknown)` + case "${UNAME_MACHINE_ARCH}" in + armeb) machine=armeb-unknown ;; + arm*) machine=arm-unknown ;; + sh3el) machine=shl-unknown ;; + sh3eb) machine=sh-unknown ;; + *) machine=${UNAME_MACHINE_ARCH}-unknown ;; + esac + # The Operating System including object format, if it has switched + # to ELF recently, or will in the future. + case "${UNAME_MACHINE_ARCH}" in + arm*|i386|m68k|ns32k|sh3*|sparc|vax) + eval $set_cc_for_build + if echo __ELF__ | $CC_FOR_BUILD -E - 2>/dev/null \ + | grep __ELF__ >/dev/null + then + # Once all utilities can be ECOFF (netbsdecoff) or a.out (netbsdaout). + # Return netbsd for either. FIX? + os=netbsd + else + os=netbsdelf + fi + ;; + *) + os=netbsd + ;; + esac + # The OS release + release=`echo ${UNAME_RELEASE}|sed -e 's/[-_].*/\./'` + # Since CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM: + # contains redundant information, the shorter form: + # CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM is used. + echo "${machine}-${os}${release}" + exit 0 ;; + amiga:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + arc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + hp300:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mac68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + macppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme88k:OpenBSD:*:*) + echo m88k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvmeppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + pmax:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sgi:OpenBSD:*:*) + echo mipseb-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sun3:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + wgrisc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + *:OpenBSD:*:*) + echo ${UNAME_MACHINE}-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + alpha:OSF1:*:*) + if test $UNAME_RELEASE = "V4.0"; then + UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $3}'` + fi + # A Vn.n version is a released version. + # A Tn.n version is a released field test version. + # A Xn.n version is an unreleased experimental baselevel. + # 1.2 uses "1.2" for uname -r. + eval $set_cc_for_build + cat <$dummy.s + .data +\$Lformat: + .byte 37,100,45,37,120,10,0 # "%d-%x\n" + + .text + .globl main + .align 4 + .ent main +main: + .frame \$30,16,\$26,0 + ldgp \$29,0(\$27) + .prologue 1 + .long 0x47e03d80 # implver \$0 + lda \$2,-1 + .long 0x47e20c21 # amask \$2,\$1 + lda \$16,\$Lformat + mov \$0,\$17 + not \$1,\$18 + jsr \$26,printf + ldgp \$29,0(\$26) + mov 0,\$16 + jsr \$26,exit + .end main +EOF + $CC_FOR_BUILD $dummy.s -o $dummy 2>/dev/null + if test "$?" = 0 ; then + case `$dummy` in + 0-0) + UNAME_MACHINE="alpha" + ;; + 1-0) + UNAME_MACHINE="alphaev5" + ;; + 1-1) + UNAME_MACHINE="alphaev56" + ;; + 1-101) + UNAME_MACHINE="alphapca56" + ;; + 2-303) + UNAME_MACHINE="alphaev6" + ;; + 2-307) + UNAME_MACHINE="alphaev67" + ;; + 2-1307) + UNAME_MACHINE="alphaev68" + ;; + 3-1307) + UNAME_MACHINE="alphaev7" + ;; + esac + fi + rm -f $dummy.s $dummy && rmdir $tmpdir + echo ${UNAME_MACHINE}-dec-osf`echo ${UNAME_RELEASE} | sed -e 's/^[VTX]//' | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + exit 0 ;; + Alpha\ *:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # Should we change UNAME_MACHINE based on the output of uname instead + # of the specific Alpha model? + echo alpha-pc-interix + exit 0 ;; + 21064:Windows_NT:50:3) + echo alpha-dec-winnt3.5 + exit 0 ;; + Amiga*:UNIX_System_V:4.0:*) + echo m68k-unknown-sysv4 + exit 0;; + *:[Aa]miga[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-amigaos + exit 0 ;; + *:[Mm]orph[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-morphos + exit 0 ;; + *:OS/390:*:*) + echo i370-ibm-openedition + exit 0 ;; + arm:RISC*:1.[012]*:*|arm:riscix:1.[012]*:*) + echo arm-acorn-riscix${UNAME_RELEASE} + exit 0;; + SR2?01:HI-UX/MPP:*:* | SR8000:HI-UX/MPP:*:*) + echo hppa1.1-hitachi-hiuxmpp + exit 0;; + Pyramid*:OSx*:*:* | MIS*:OSx*:*:* | MIS*:SMP_DC-OSx*:*:*) + # akee@wpdis03.wpafb.af.mil (Earle F. Ake) contributed MIS and NILE. + if test "`(/bin/universe) 2>/dev/null`" = att ; then + echo pyramid-pyramid-sysv3 + else + echo pyramid-pyramid-bsd + fi + exit 0 ;; + NILE*:*:*:dcosx) + echo pyramid-pyramid-svr4 + exit 0 ;; + DRS?6000:UNIX_SV:4.2*:7*) + case `/usr/bin/uname -p` in + sparc) echo sparc-icl-nx7 && exit 0 ;; + esac ;; + sun4H:SunOS:5.*:*) + echo sparc-hal-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:5.*:* | tadpole*:SunOS:5.*:*) + echo sparc-sun-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + i86pc:SunOS:5.*:*) + echo i386-pc-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:6*:*) + # According to config.sub, this is the proper way to canonicalize + # SunOS6. Hard to guess exactly what SunOS6 will be like, but + # it's likely to be more like Solaris than SunOS4. + echo sparc-sun-solaris3`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:*:*) + case "`/usr/bin/arch -k`" in + Series*|S4*) + UNAME_RELEASE=`uname -v` + ;; + esac + # Japanese Language versions have a version number like `4.1.3-JL'. + echo sparc-sun-sunos`echo ${UNAME_RELEASE}|sed -e 's/-/_/'` + exit 0 ;; + sun3*:SunOS:*:*) + echo m68k-sun-sunos${UNAME_RELEASE} + exit 0 ;; + sun*:*:4.2BSD:*) + UNAME_RELEASE=`(sed 1q /etc/motd | awk '{print substr($5,1,3)}') 2>/dev/null` + test "x${UNAME_RELEASE}" = "x" && UNAME_RELEASE=3 + case "`/bin/arch`" in + sun3) + echo m68k-sun-sunos${UNAME_RELEASE} + ;; + sun4) + echo sparc-sun-sunos${UNAME_RELEASE} + ;; + esac + exit 0 ;; + aushp:SunOS:*:*) + echo sparc-auspex-sunos${UNAME_RELEASE} + exit 0 ;; + # The situation for MiNT is a little confusing. The machine name + # can be virtually everything (everything which is not + # "atarist" or "atariste" at least should have a processor + # > m68000). The system name ranges from "MiNT" over "FreeMiNT" + # to the lowercase version "mint" (or "freemint"). Finally + # the system name "TOS" denotes a system which is actually not + # MiNT. But MiNT is downward compatible to TOS, so this should + # be no problem. + atarist[e]:*MiNT:*:* | atarist[e]:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + atari*:*MiNT:*:* | atari*:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + *falcon*:*MiNT:*:* | *falcon*:*mint:*:* | *falcon*:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + milan*:*MiNT:*:* | milan*:*mint:*:* | *milan*:*TOS:*:*) + echo m68k-milan-mint${UNAME_RELEASE} + exit 0 ;; + hades*:*MiNT:*:* | hades*:*mint:*:* | *hades*:*TOS:*:*) + echo m68k-hades-mint${UNAME_RELEASE} + exit 0 ;; + *:*MiNT:*:* | *:*mint:*:* | *:*TOS:*:*) + echo m68k-unknown-mint${UNAME_RELEASE} + exit 0 ;; + powerpc:machten:*:*) + echo powerpc-apple-machten${UNAME_RELEASE} + exit 0 ;; + RISC*:Mach:*:*) + echo mips-dec-mach_bsd4.3 + exit 0 ;; + RISC*:ULTRIX:*:*) + echo mips-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + VAX*:ULTRIX*:*:*) + echo vax-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + 2020:CLIX:*:* | 2430:CLIX:*:*) + echo clipper-intergraph-clix${UNAME_RELEASE} + exit 0 ;; + mips:*:*:UMIPS | mips:*:*:RISCos) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c +#ifdef __cplusplus +#include /* for printf() prototype */ + int main (int argc, char *argv[]) { +#else + int main (argc, argv) int argc; char *argv[]; { +#endif + #if defined (host_mips) && defined (MIPSEB) + #if defined (SYSTYPE_SYSV) + printf ("mips-mips-riscos%ssysv\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_SVR4) + printf ("mips-mips-riscos%ssvr4\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_BSD43) || defined(SYSTYPE_BSD) + printf ("mips-mips-riscos%sbsd\n", argv[1]); exit (0); + #endif + #endif + exit (-1); + } +EOF + $CC_FOR_BUILD $dummy.c -o $dummy \ + && $dummy `echo "${UNAME_RELEASE}" | sed -n 's/\([0-9]*\).*/\1/p'` \ + && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0 + rm -f $dummy.c $dummy && rmdir $tmpdir + echo mips-mips-riscos${UNAME_RELEASE} + exit 0 ;; + Motorola:PowerMAX_OS:*:*) + echo powerpc-motorola-powermax + exit 0 ;; + Night_Hawk:*:*:PowerMAX_OS) + echo powerpc-harris-powermax + exit 0 ;; + Night_Hawk:Power_UNIX:*:*) + echo powerpc-harris-powerunix + exit 0 ;; + m88k:CX/UX:7*:*) + echo m88k-harris-cxux7 + exit 0 ;; + m88k:*:4*:R4*) + echo m88k-motorola-sysv4 + exit 0 ;; + m88k:*:3*:R3*) + echo m88k-motorola-sysv3 + exit 0 ;; + AViiON:dgux:*:*) + # DG/UX returns AViiON for all architectures + UNAME_PROCESSOR=`/usr/bin/uname -p` + if [ $UNAME_PROCESSOR = mc88100 ] || [ $UNAME_PROCESSOR = mc88110 ] + then + if [ ${TARGET_BINARY_INTERFACE}x = m88kdguxelfx ] || \ + [ ${TARGET_BINARY_INTERFACE}x = x ] + then + echo m88k-dg-dgux${UNAME_RELEASE} + else + echo m88k-dg-dguxbcs${UNAME_RELEASE} + fi + else + echo i586-dg-dgux${UNAME_RELEASE} + fi + exit 0 ;; + M88*:DolphinOS:*:*) # DolphinOS (SVR3) + echo m88k-dolphin-sysv3 + exit 0 ;; + M88*:*:R3*:*) + # Delta 88k system running SVR3 + echo m88k-motorola-sysv3 + exit 0 ;; + XD88*:*:*:*) # Tektronix XD88 system running UTekV (SVR3) + echo m88k-tektronix-sysv3 + exit 0 ;; + Tek43[0-9][0-9]:UTek:*:*) # Tektronix 4300 system running UTek (BSD) + echo m68k-tektronix-bsd + exit 0 ;; + *:IRIX*:*:*) + echo mips-sgi-irix`echo ${UNAME_RELEASE}|sed -e 's/-/_/g'` + exit 0 ;; + ????????:AIX?:[12].1:2) # AIX 2.2.1 or AIX 2.1.1 is RT/PC AIX. + echo romp-ibm-aix # uname -m gives an 8 hex-code CPU id + exit 0 ;; # Note that: echo "'`uname -s`'" gives 'AIX ' + i*86:AIX:*:*) + echo i386-ibm-aix + exit 0 ;; + ia64:AIX:*:*) + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${UNAME_MACHINE}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:2:3) + if grep bos325 /usr/include/stdio.h >/dev/null 2>&1; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + + main() + { + if (!__power_pc()) + exit(1); + puts("powerpc-ibm-aix3.2.5"); + exit(0); + } +EOF + $CC_FOR_BUILD $dummy.c -o $dummy && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0 + rm -f $dummy.c $dummy && rmdir $tmpdir + echo rs6000-ibm-aix3.2.5 + elif grep bos324 /usr/include/stdio.h >/dev/null 2>&1; then + echo rs6000-ibm-aix3.2.4 + else + echo rs6000-ibm-aix3.2 + fi + exit 0 ;; + *:AIX:*:[45]) + IBM_CPU_ID=`/usr/sbin/lsdev -C -c processor -S available | sed 1q | awk '{ print $1 }'` + if /usr/sbin/lsattr -El ${IBM_CPU_ID} | grep ' POWER' >/dev/null 2>&1; then + IBM_ARCH=rs6000 + else + IBM_ARCH=powerpc + fi + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${IBM_ARCH}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:*:*) + echo rs6000-ibm-aix + exit 0 ;; + ibmrt:4.4BSD:*|romp-ibm:BSD:*) + echo romp-ibm-bsd4.4 + exit 0 ;; + ibmrt:*BSD:*|romp-ibm:BSD:*) # covers RT/PC BSD and + echo romp-ibm-bsd${UNAME_RELEASE} # 4.3 with uname added to + exit 0 ;; # report: romp-ibm BSD 4.3 + *:BOSX:*:*) + echo rs6000-bull-bosx + exit 0 ;; + DPX/2?00:B.O.S.:*:*) + echo m68k-bull-sysv3 + exit 0 ;; + 9000/[34]??:4.3bsd:1.*:*) + echo m68k-hp-bsd + exit 0 ;; + hp300:4.4BSD:*:* | 9000/[34]??:4.3bsd:2.*:*) + echo m68k-hp-bsd4.4 + exit 0 ;; + 9000/[34678]??:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + case "${UNAME_MACHINE}" in + 9000/31? ) HP_ARCH=m68000 ;; + 9000/[34]?? ) HP_ARCH=m68k ;; + 9000/[678][0-9][0-9]) + if [ -x /usr/bin/getconf ]; then + sc_cpu_version=`/usr/bin/getconf SC_CPU_VERSION 2>/dev/null` + sc_kernel_bits=`/usr/bin/getconf SC_KERNEL_BITS 2>/dev/null` + case "${sc_cpu_version}" in + 523) HP_ARCH="hppa1.0" ;; # CPU_PA_RISC1_0 + 528) HP_ARCH="hppa1.1" ;; # CPU_PA_RISC1_1 + 532) # CPU_PA_RISC2_0 + case "${sc_kernel_bits}" in + 32) HP_ARCH="hppa2.0n" ;; + 64) HP_ARCH="hppa2.0w" ;; + '') HP_ARCH="hppa2.0" ;; # HP-UX 10.20 + esac ;; + esac + fi + if [ "${HP_ARCH}" = "" ]; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + + #define _HPUX_SOURCE + #include + #include + + int main () + { + #if defined(_SC_KERNEL_BITS) + long bits = sysconf(_SC_KERNEL_BITS); + #endif + long cpu = sysconf (_SC_CPU_VERSION); + + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1"); break; + case CPU_PA_RISC2_0: + #if defined(_SC_KERNEL_BITS) + switch (bits) + { + case 64: puts ("hppa2.0w"); break; + case 32: puts ("hppa2.0n"); break; + default: puts ("hppa2.0"); break; + } break; + #else /* !defined(_SC_KERNEL_BITS) */ + puts ("hppa2.0"); break; + #endif + default: puts ("hppa1.0"); break; + } + exit (0); + } +EOF + (CCOPTS= $CC_FOR_BUILD $dummy.c -o $dummy 2>/dev/null) && HP_ARCH=`$dummy` + if test -z "$HP_ARCH"; then HP_ARCH=hppa; fi + rm -f $dummy.c $dummy && rmdir $tmpdir + fi ;; + esac + echo ${HP_ARCH}-hp-hpux${HPUX_REV} + exit 0 ;; + ia64:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + echo ia64-hp-hpux${HPUX_REV} + exit 0 ;; + 3050*:HI-UX:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + int + main () + { + long cpu = sysconf (_SC_CPU_VERSION); + /* The order matters, because CPU_IS_HP_MC68K erroneously returns + true for CPU_PA_RISC1_0. CPU_IS_PA_RISC returns correct + results, however. */ + if (CPU_IS_PA_RISC (cpu)) + { + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0-hitachi-hiuxwe2"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1-hitachi-hiuxwe2"); break; + case CPU_PA_RISC2_0: puts ("hppa2.0-hitachi-hiuxwe2"); break; + default: puts ("hppa-hitachi-hiuxwe2"); break; + } + } + else if (CPU_IS_HP_MC68K (cpu)) + puts ("m68k-hitachi-hiuxwe2"); + else puts ("unknown-hitachi-hiuxwe2"); + exit (0); + } +EOF + $CC_FOR_BUILD $dummy.c -o $dummy && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0 + rm -f $dummy.c $dummy && rmdir $tmpdir + echo unknown-hitachi-hiuxwe2 + exit 0 ;; + 9000/7??:4.3bsd:*:* | 9000/8?[79]:4.3bsd:*:* ) + echo hppa1.1-hp-bsd + exit 0 ;; + 9000/8??:4.3bsd:*:*) + echo hppa1.0-hp-bsd + exit 0 ;; + *9??*:MPE/iX:*:* | *3000*:MPE/iX:*:*) + echo hppa1.0-hp-mpeix + exit 0 ;; + hp7??:OSF1:*:* | hp8?[79]:OSF1:*:* ) + echo hppa1.1-hp-osf + exit 0 ;; + hp8??:OSF1:*:*) + echo hppa1.0-hp-osf + exit 0 ;; + i*86:OSF1:*:*) + if [ -x /usr/sbin/sysversion ] ; then + echo ${UNAME_MACHINE}-unknown-osf1mk + else + echo ${UNAME_MACHINE}-unknown-osf1 + fi + exit 0 ;; + parisc*:Lites*:*:*) + echo hppa1.1-hp-lites + exit 0 ;; + C1*:ConvexOS:*:* | convex:ConvexOS:C1*:*) + echo c1-convex-bsd + exit 0 ;; + C2*:ConvexOS:*:* | convex:ConvexOS:C2*:*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + C34*:ConvexOS:*:* | convex:ConvexOS:C34*:*) + echo c34-convex-bsd + exit 0 ;; + C38*:ConvexOS:*:* | convex:ConvexOS:C38*:*) + echo c38-convex-bsd + exit 0 ;; + C4*:ConvexOS:*:* | convex:ConvexOS:C4*:*) + echo c4-convex-bsd + exit 0 ;; + CRAY*Y-MP:*:*:*) + echo ymp-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*[A-Z]90:*:*:*) + echo ${UNAME_MACHINE}-cray-unicos${UNAME_RELEASE} \ + | sed -e 's/CRAY.*\([A-Z]90\)/\1/' \ + -e y/ABCDEFGHIJKLMNOPQRSTUVWXYZ/abcdefghijklmnopqrstuvwxyz/ \ + -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*TS:*:*:*) + echo t90-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*T3D:*:*:*) + echo alpha-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*T3E:*:*:*) + echo alphaev5-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*SV1:*:*:*) + echo sv1-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + F30[01]:UNIX_System_V:*:* | F700:UNIX_System_V:*:*) + FUJITSU_PROC=`uname -m | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'` + FUJITSU_REL=`echo ${UNAME_RELEASE} | sed -e 's/ /_/'` + echo "${FUJITSU_PROC}-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}" + exit 0 ;; + i*86:BSD/386:*:* | i*86:BSD/OS:*:* | *:Ascend\ Embedded/OS:*:*) + echo ${UNAME_MACHINE}-pc-bsdi${UNAME_RELEASE} + exit 0 ;; + sparc*:BSD/OS:*:*) + echo sparc-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:BSD/OS:*:*) + echo ${UNAME_MACHINE}-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:FreeBSD:*:*) + # Determine whether the default compiler uses glibc. + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + #if __GLIBC__ >= 2 + LIBC=gnu + #else + LIBC= + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=` + rm -f $dummy.c && rmdir $tmpdir + echo ${UNAME_MACHINE}-unknown-freebsd`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'`${LIBC:+-$LIBC} + exit 0 ;; + i*:CYGWIN*:*) + echo ${UNAME_MACHINE}-pc-cygwin + exit 0 ;; + i*:MINGW*:*) + echo ${UNAME_MACHINE}-pc-mingw32 + exit 0 ;; + i*:PW*:*) + echo ${UNAME_MACHINE}-pc-pw32 + exit 0 ;; + x86:Interix*:3*) + echo i386-pc-interix3 + exit 0 ;; + i*:Windows_NT*:* | Pentium*:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # It also conflicts with pre-2.0 versions of AT&T UWIN. Should we + # UNAME_MACHINE based on the output of uname instead of i386? + echo i386-pc-interix + exit 0 ;; + i*:UWIN*:*) + echo ${UNAME_MACHINE}-pc-uwin + exit 0 ;; + p*:CYGWIN*:*) + echo powerpcle-unknown-cygwin + exit 0 ;; + prep*:SunOS:5.*:*) + echo powerpcle-unknown-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + *:GNU:*:*) + echo `echo ${UNAME_MACHINE}|sed -e 's,[-/].*$,,'`-unknown-gnu`echo ${UNAME_RELEASE}|sed -e 's,/.*$,,'` + exit 0 ;; + i*86:Minix:*:*) + echo ${UNAME_MACHINE}-pc-minix + exit 0 ;; + arm*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + ia64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + m68*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + mips:Linux:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #undef CPU + #undef mips + #undef mipsel + #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) + CPU=mipsel + #else + #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) + CPU=mips + #else + CPU= + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=` + rm -f $dummy.c && rmdir $tmpdir + test x"${CPU}" != x && echo "${CPU}-pc-linux-gnu" && exit 0 + ;; + ppc:Linux:*:*) + echo powerpc-unknown-linux-gnu + exit 0 ;; + ppc64:Linux:*:*) + echo powerpc64-unknown-linux-gnu + exit 0 ;; + alpha:Linux:*:*) + case `sed -n '/^cpu model/s/^.*: \(.*\)/\1/p' < /proc/cpuinfo` in + EV5) UNAME_MACHINE=alphaev5 ;; + EV56) UNAME_MACHINE=alphaev56 ;; + PCA56) UNAME_MACHINE=alphapca56 ;; + PCA57) UNAME_MACHINE=alphapca56 ;; + EV6) UNAME_MACHINE=alphaev6 ;; + EV67) UNAME_MACHINE=alphaev67 ;; + EV68*) UNAME_MACHINE=alphaev68 ;; + esac + objdump --private-headers /bin/sh | grep ld.so.1 >/dev/null + if test "$?" = 0 ; then LIBC="libc1" ; else LIBC="" ; fi + echo ${UNAME_MACHINE}-unknown-linux-gnu${LIBC} + exit 0 ;; + parisc:Linux:*:* | hppa:Linux:*:*) + # Look for CPU level + case `grep '^cpu[^a-z]*:' /proc/cpuinfo 2>/dev/null | cut -d' ' -f2` in + PA7*) echo hppa1.1-unknown-linux-gnu ;; + PA8*) echo hppa2.0-unknown-linux-gnu ;; + *) echo hppa-unknown-linux-gnu ;; + esac + exit 0 ;; + parisc64:Linux:*:* | hppa64:Linux:*:*) + echo hppa64-unknown-linux-gnu + exit 0 ;; + s390:Linux:*:* | s390x:Linux:*:*) + echo ${UNAME_MACHINE}-ibm-linux + exit 0 ;; + sh*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + sparc:Linux:*:* | sparc64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + x86_64:Linux:*:*) + echo x86_64-unknown-linux-gnu + exit 0 ;; + i*86:Linux:*:*) + # The BFD linker knows what the default object file format is, so + # first see if it will tell us. cd to the root directory to prevent + # problems with other programs or directories called `ld' in the path. + # Set LC_ALL=C to ensure ld outputs messages in English. + ld_supported_targets=`cd /; LC_ALL=C ld --help 2>&1 \ + | sed -ne '/supported targets:/!d + s/[ ][ ]*/ /g + s/.*supported targets: *// + s/ .*// + p'` + case "$ld_supported_targets" in + elf32-i386) + TENTATIVE="${UNAME_MACHINE}-pc-linux-gnu" + ;; + a.out-i386-linux) + echo "${UNAME_MACHINE}-pc-linux-gnuaout" + exit 0 ;; + coff-i386) + echo "${UNAME_MACHINE}-pc-linux-gnucoff" + exit 0 ;; + "") + # Either a pre-BFD a.out linker (linux-gnuoldld) or + # one that does not give us useful --help. + echo "${UNAME_MACHINE}-pc-linux-gnuoldld" + exit 0 ;; + esac + # Determine whether the default compiler is a.out or elf + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + #ifdef __ELF__ + # ifdef __GLIBC__ + # if __GLIBC__ >= 2 + LIBC=gnu + # else + LIBC=gnulibc1 + # endif + # else + LIBC=gnulibc1 + # endif + #else + #ifdef __INTEL_COMPILER + LIBC=gnu + #else + LIBC=gnuaout + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=` + rm -f $dummy.c && rmdir $tmpdir + test x"${LIBC}" != x && echo "${UNAME_MACHINE}-pc-linux-${LIBC}" && exit 0 + test x"${TENTATIVE}" != x && echo "${TENTATIVE}" && exit 0 + ;; + i*86:DYNIX/ptx:4*:*) + # ptx 4.0 does uname -s correctly, with DYNIX/ptx in there. + # earlier versions are messed up and put the nodename in both + # sysname and nodename. + echo i386-sequent-sysv4 + exit 0 ;; + i*86:UNIX_SV:4.2MP:2.*) + # Unixware is an offshoot of SVR4, but it has its own version + # number series starting with 2... + # I am not positive that other SVR4 systems won't match this, + # I just have to hope. -- rms. + # Use sysv4.2uw... so that sysv4* matches it. + echo ${UNAME_MACHINE}-pc-sysv4.2uw${UNAME_VERSION} + exit 0 ;; + i*86:*:4.*:* | i*86:SYSTEM_V:4.*:*) + UNAME_REL=`echo ${UNAME_RELEASE} | sed 's/\/MP$//'` + if grep Novell /usr/include/link.h >/dev/null 2>/dev/null; then + echo ${UNAME_MACHINE}-univel-sysv${UNAME_REL} + else + echo ${UNAME_MACHINE}-pc-sysv${UNAME_REL} + fi + exit 0 ;; + i*86:*:5:[78]*) + case `/bin/uname -X | grep "^Machine"` in + *486*) UNAME_MACHINE=i486 ;; + *Pentium) UNAME_MACHINE=i586 ;; + *Pent*|*Celeron) UNAME_MACHINE=i686 ;; + esac + echo ${UNAME_MACHINE}-unknown-sysv${UNAME_RELEASE}${UNAME_SYSTEM}${UNAME_VERSION} + exit 0 ;; + i*86:*:3.2:*) + if test -f /usr/options/cb.name; then + UNAME_REL=`sed -n 's/.*Version //p' /dev/null >/dev/null ; then + UNAME_REL=`(/bin/uname -X|grep Release|sed -e 's/.*= //')` + (/bin/uname -X|grep i80486 >/dev/null) && UNAME_MACHINE=i486 + (/bin/uname -X|grep '^Machine.*Pentium' >/dev/null) \ + && UNAME_MACHINE=i586 + (/bin/uname -X|grep '^Machine.*Pent *II' >/dev/null) \ + && UNAME_MACHINE=i686 + (/bin/uname -X|grep '^Machine.*Pentium Pro' >/dev/null) \ + && UNAME_MACHINE=i686 + echo ${UNAME_MACHINE}-pc-sco$UNAME_REL + else + echo ${UNAME_MACHINE}-pc-sysv32 + fi + exit 0 ;; + i*86:*DOS:*:*) + echo ${UNAME_MACHINE}-pc-msdosdjgpp + exit 0 ;; + pc:*:*:*) + # Left here for compatibility: + # uname -m prints for DJGPP always 'pc', but it prints nothing about + # the processor, so we play safe by assuming i386. + echo i386-pc-msdosdjgpp + exit 0 ;; + Intel:Mach:3*:*) + echo i386-pc-mach3 + exit 0 ;; + paragon:*:*:*) + echo i860-intel-osf1 + exit 0 ;; + i860:*:4.*:*) # i860-SVR4 + if grep Stardent /usr/include/sys/uadmin.h >/dev/null 2>&1 ; then + echo i860-stardent-sysv${UNAME_RELEASE} # Stardent Vistra i860-SVR4 + else # Add other i860-SVR4 vendors below as they are discovered. + echo i860-unknown-sysv${UNAME_RELEASE} # Unknown i860-SVR4 + fi + exit 0 ;; + mini*:CTIX:SYS*5:*) + # "miniframe" + echo m68010-convergent-sysv + exit 0 ;; + M68*:*:R3V[567]*:*) + test -r /sysV68 && echo 'm68k-motorola-sysv' && exit 0 ;; + 3[34]??:*:4.0:3.0 | 3[34]??A:*:4.0:3.0 | 3[34]??,*:*:4.0:3.0 | 3[34]??/*:*:4.0:3.0 | 4400:*:4.0:3.0 | 4850:*:4.0:3.0 | SKA40:*:4.0:3.0) + OS_REL='' + test -r /etc/.relid \ + && OS_REL=.`sed -n 's/[^ ]* [^ ]* \([0-9][0-9]\).*/\1/p' < /etc/.relid` + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4.3${OS_REL} && exit 0 + /bin/uname -p 2>/dev/null | /bin/grep entium >/dev/null \ + && echo i586-ncr-sysv4.3${OS_REL} && exit 0 ;; + 3[34]??:*:4.0:* | 3[34]??,*:*:4.0:*) + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4 && exit 0 ;; + m68*:LynxOS:2.*:* | m68*:LynxOS:3.0*:*) + echo m68k-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + mc68030:UNIX_System_V:4.*:*) + echo m68k-atari-sysv4 + exit 0 ;; + i*86:LynxOS:2.*:* | i*86:LynxOS:3.[01]*:* | i*86:LynxOS:4.0*:*) + echo i386-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + TSUNAMI:LynxOS:2.*:*) + echo sparc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + rs6000:LynxOS:2.*:*) + echo rs6000-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + PowerPC:LynxOS:2.*:* | PowerPC:LynxOS:3.[01]*:* | PowerPC:LynxOS:4.0*:*) + echo powerpc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + SM[BE]S:UNIX_SV:*:*) + echo mips-dde-sysv${UNAME_RELEASE} + exit 0 ;; + RM*:ReliantUNIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + RM*:SINIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + *:SINIX-*:*:*) + if uname -p 2>/dev/null >/dev/null ; then + UNAME_MACHINE=`(uname -p) 2>/dev/null` + echo ${UNAME_MACHINE}-sni-sysv4 + else + echo ns32k-sni-sysv + fi + exit 0 ;; + PENTIUM:*:4.0*:*) # Unisys `ClearPath HMP IX 4000' SVR4/MP effort + # says + echo i586-unisys-sysv4 + exit 0 ;; + *:UNIX_System_V:4*:FTX*) + # From Gerald Hewes . + # How about differentiating between stratus architectures? -djm + echo hppa1.1-stratus-sysv4 + exit 0 ;; + *:*:*:FTX*) + # From seanf@swdc.stratus.com. + echo i860-stratus-sysv4 + exit 0 ;; + *:VOS:*:*) + # From Paul.Green@stratus.com. + echo hppa1.1-stratus-vos + exit 0 ;; + mc68*:A/UX:*:*) + echo m68k-apple-aux${UNAME_RELEASE} + exit 0 ;; + news*:NEWS-OS:6*:*) + echo mips-sony-newsos6 + exit 0 ;; + R[34]000:*System_V*:*:* | R4000:UNIX_SYSV:*:* | R*000:UNIX_SV:*:*) + if [ -d /usr/nec ]; then + echo mips-nec-sysv${UNAME_RELEASE} + else + echo mips-unknown-sysv${UNAME_RELEASE} + fi + exit 0 ;; + BeBox:BeOS:*:*) # BeOS running on hardware made by Be, PPC only. + echo powerpc-be-beos + exit 0 ;; + BeMac:BeOS:*:*) # BeOS running on Mac or Mac clone, PPC only. + echo powerpc-apple-beos + exit 0 ;; + BePC:BeOS:*:*) # BeOS running on Intel PC compatible. + echo i586-pc-beos + exit 0 ;; + SX-4:SUPER-UX:*:*) + echo sx4-nec-superux${UNAME_RELEASE} + exit 0 ;; + SX-5:SUPER-UX:*:*) + echo sx5-nec-superux${UNAME_RELEASE} + exit 0 ;; + Power*:Rhapsody:*:*) + echo powerpc-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Rhapsody:*:*) + echo ${UNAME_MACHINE}-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Darwin:*:*) + echo `uname -p`-apple-darwin${UNAME_RELEASE} + exit 0 ;; + *:procnto*:*:* | *:QNX:[0123456789]*:*) + UNAME_PROCESSOR=`uname -p` + if test "$UNAME_PROCESSOR" = "x86"; then + UNAME_PROCESSOR=i386 + UNAME_MACHINE=pc + fi + echo ${UNAME_PROCESSOR}-${UNAME_MACHINE}-nto-qnx${UNAME_RELEASE} + exit 0 ;; + *:QNX:*:4*) + echo i386-pc-qnx + exit 0 ;; + NSR-[GKLNPTVW]:NONSTOP_KERNEL:*:*) + echo nsr-tandem-nsk${UNAME_RELEASE} + exit 0 ;; + *:NonStop-UX:*:*) + echo mips-compaq-nonstopux + exit 0 ;; + BS2000:POSIX*:*:*) + echo bs2000-siemens-sysv + exit 0 ;; + DS/*:UNIX_System_V:*:*) + echo ${UNAME_MACHINE}-${UNAME_SYSTEM}-${UNAME_RELEASE} + exit 0 ;; + *:Plan9:*:*) + # "uname -m" is not consistent, so use $cputype instead. 386 + # is converted to i386 for consistency with other x86 + # operating systems. + if test "$cputype" = "386"; then + UNAME_MACHINE=i386 + else + UNAME_MACHINE="$cputype" + fi + echo ${UNAME_MACHINE}-unknown-plan9 + exit 0 ;; + i*86:OS/2:*:*) + # If we were able to find `uname', then EMX Unix compatibility + # is probably installed. + echo ${UNAME_MACHINE}-pc-os2-emx + exit 0 ;; + *:TOPS-10:*:*) + echo pdp10-unknown-tops10 + exit 0 ;; + *:TENEX:*:*) + echo pdp10-unknown-tenex + exit 0 ;; + KS10:TOPS-20:*:* | KL10:TOPS-20:*:* | TYPE4:TOPS-20:*:*) + echo pdp10-dec-tops20 + exit 0 ;; + XKL-1:TOPS-20:*:* | TYPE5:TOPS-20:*:*) + echo pdp10-xkl-tops20 + exit 0 ;; + *:TOPS-20:*:*) + echo pdp10-unknown-tops20 + exit 0 ;; + *:ITS:*:*) + echo pdp10-unknown-its + exit 0 ;; + i*86:XTS-300:*:STOP) + echo ${UNAME_MACHINE}-unknown-stop + exit 0 ;; + i*86:atheos:*:*) + echo ${UNAME_MACHINE}-unknown-atheos + exit 0 ;; +esac + +#echo '(No uname command or uname output not recognized.)' 1>&2 +#echo "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" 1>&2 + +eval $set_cc_for_build +cat >$dummy.c < +# include +#endif +main () +{ +#if defined (sony) +#if defined (MIPSEB) + /* BFD wants "bsd" instead of "newsos". Perhaps BFD should be changed, + I don't know.... */ + printf ("mips-sony-bsd\n"); exit (0); +#else +#include + printf ("m68k-sony-newsos%s\n", +#ifdef NEWSOS4 + "4" +#else + "" +#endif + ); exit (0); +#endif +#endif + +#if defined (__arm) && defined (__acorn) && defined (__unix) + printf ("arm-acorn-riscix"); exit (0); +#endif + +#if defined (hp300) && !defined (hpux) + printf ("m68k-hp-bsd\n"); exit (0); +#endif + +#if defined (NeXT) +#if !defined (__ARCHITECTURE__) +#define __ARCHITECTURE__ "m68k" +#endif + int version; + version=`(hostinfo | sed -n 's/.*NeXT Mach \([0-9]*\).*/\1/p') 2>/dev/null`; + if (version < 4) + printf ("%s-next-nextstep%d\n", __ARCHITECTURE__, version); + else + printf ("%s-next-openstep%d\n", __ARCHITECTURE__, version); + exit (0); +#endif + +#if defined (MULTIMAX) || defined (n16) +#if defined (UMAXV) + printf ("ns32k-encore-sysv\n"); exit (0); +#else +#if defined (CMU) + printf ("ns32k-encore-mach\n"); exit (0); +#else + printf ("ns32k-encore-bsd\n"); exit (0); +#endif +#endif +#endif + +#if defined (__386BSD__) + printf ("i386-pc-bsd\n"); exit (0); +#endif + +#if defined (sequent) +#if defined (i386) + printf ("i386-sequent-dynix\n"); exit (0); +#endif +#if defined (ns32000) + printf ("ns32k-sequent-dynix\n"); exit (0); +#endif +#endif + +#if defined (_SEQUENT_) + struct utsname un; + + uname(&un); + + if (strncmp(un.version, "V2", 2) == 0) { + printf ("i386-sequent-ptx2\n"); exit (0); + } + if (strncmp(un.version, "V1", 2) == 0) { /* XXX is V1 correct? */ + printf ("i386-sequent-ptx1\n"); exit (0); + } + printf ("i386-sequent-ptx\n"); exit (0); + +#endif + +#if defined (vax) +# if !defined (ultrix) +# include +# if defined (BSD) +# if BSD == 43 + printf ("vax-dec-bsd4.3\n"); exit (0); +# else +# if BSD == 199006 + printf ("vax-dec-bsd4.3reno\n"); exit (0); +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# endif +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# else + printf ("vax-dec-ultrix\n"); exit (0); +# endif +#endif + +#if defined (alliant) && defined (i860) + printf ("i860-alliant-bsd\n"); exit (0); +#endif + + exit (1); +} +EOF + +$CC_FOR_BUILD $dummy.c -o $dummy 2>/dev/null && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0 +rm -f $dummy.c $dummy && rmdir $tmpdir + +# Apollos put the system type in the environment. + +test -d /usr/apollo && { echo ${ISP}-apollo-${SYSTYPE}; exit 0; } + +# Convex versions that predate uname can use getsysinfo(1) + +if [ -x /usr/convex/getsysinfo ] +then + case `getsysinfo -f cpu_type` in + c1*) + echo c1-convex-bsd + exit 0 ;; + c2*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + c34*) + echo c34-convex-bsd + exit 0 ;; + c38*) + echo c38-convex-bsd + exit 0 ;; + c4*) + echo c4-convex-bsd + exit 0 ;; + esac +fi + +cat >&2 < in order to provide the needed +information to handle your system. + +config.guess timestamp = $timestamp + +uname -m = `(uname -m) 2>/dev/null || echo unknown` +uname -r = `(uname -r) 2>/dev/null || echo unknown` +uname -s = `(uname -s) 2>/dev/null || echo unknown` +uname -v = `(uname -v) 2>/dev/null || echo unknown` + +/usr/bin/uname -p = `(/usr/bin/uname -p) 2>/dev/null` +/bin/uname -X = `(/bin/uname -X) 2>/dev/null` + +hostinfo = `(hostinfo) 2>/dev/null` +/bin/universe = `(/bin/universe) 2>/dev/null` +/usr/bin/arch -k = `(/usr/bin/arch -k) 2>/dev/null` +/bin/arch = `(/bin/arch) 2>/dev/null` +/usr/bin/oslevel = `(/usr/bin/oslevel) 2>/dev/null` +/usr/convex/getsysinfo = `(/usr/convex/getsysinfo) 2>/dev/null` + +UNAME_MACHINE = ${UNAME_MACHINE} +UNAME_RELEASE = ${UNAME_RELEASE} +UNAME_SYSTEM = ${UNAME_SYSTEM} +UNAME_VERSION = ${UNAME_VERSION} +EOF + +exit 1 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "timestamp='" +# time-stamp-format: "%:y-%02m-%02d" +# time-stamp-end: "'" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h new file mode 100755 index 00000000..2ae6546d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h @@ -0,0 +1,74 @@ +/* config.h. Generated by configure. */ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the header file. */ +#define HAVE_INTTYPES_H 1 + +/* Define to 1 if you have the `g2' library (-lg2). */ +#define HAVE_LIBG2 1 + +/* Define to 1 if you have the `gd' library (-lgd). */ +/* #undef HAVE_LIBGD */ + +/* Define to 1 if you have the `RNA' library (-lRNA). */ +#define HAVE_LIBRNA 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_MEMORY_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDINT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDLIB_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STRINGS_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STRING_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_STAT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_TYPES_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_UNISTD_H 1 + +/* Name of package */ +#define PACKAGE "RNAforester" + +/* Define to the address where bug reports for this package should be sent. */ +#define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" + +/* Define to the full name of this package. */ +#define PACKAGE_NAME "RNAforester" + +/* Define to the full name and version of this package. */ +#define PACKAGE_STRING "RNAforester 1.5" + +/* Define to the one symbol short name of this package. */ +#define PACKAGE_TARNAME "RNAforester" + +/* Define to the version of this package. */ +#define PACKAGE_VERSION "1.5" + +/* Define to 1 if you have the ANSI C header files. */ +/* #undef STDC_HEADERS */ + +/* Version number of package */ +#define VERSION "1.5" + +/* Define to empty if `const' does not conform to ANSI C. */ +/* #undef const */ + +/* Define to `__inline__' or `__inline' if that's what the C compiler + calls it, or to nothing if 'inline' is not supported under any name. */ +#ifndef __cplusplus +/* #undef inline */ +#endif + +/* Define to `unsigned' if does not define. */ +/* #undef size_t */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h.in new file mode 100755 index 00000000..ab253a9c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.h.in @@ -0,0 +1,73 @@ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the header file. */ +#undef HAVE_INTTYPES_H + +/* Define to 1 if you have the `g2' library (-lg2). */ +#undef HAVE_LIBG2 + +/* Define to 1 if you have the `gd' library (-lgd). */ +#undef HAVE_LIBGD + +/* Define to 1 if you have the `RNA' library (-lRNA). */ +#undef HAVE_LIBRNA + +/* Define to 1 if you have the header file. */ +#undef HAVE_MEMORY_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDINT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDLIB_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRINGS_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRING_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_STAT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_TYPES_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_UNISTD_H + +/* Name of package */ +#undef PACKAGE + +/* Define to the address where bug reports for this package should be sent. */ +#undef PACKAGE_BUGREPORT + +/* Define to the full name of this package. */ +#undef PACKAGE_NAME + +/* Define to the full name and version of this package. */ +#undef PACKAGE_STRING + +/* Define to the one symbol short name of this package. */ +#undef PACKAGE_TARNAME + +/* Define to the version of this package. */ +#undef PACKAGE_VERSION + +/* Define to 1 if you have the ANSI C header files. */ +#undef STDC_HEADERS + +/* Version number of package */ +#undef VERSION + +/* Define to empty if `const' does not conform to ANSI C. */ +#undef const + +/* Define to `__inline__' or `__inline' if that's what the C compiler + calls it, or to nothing if 'inline' is not supported under any name. */ +#ifndef __cplusplus +#undef inline +#endif + +/* Define to `unsigned' if does not define. */ +#undef size_t diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.log new file mode 100755 index 00000000..6bb87a56 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.log @@ -0,0 +1,675 @@ +This file contains any messages produced by compilers while +running configure, to aid debugging if configure makes a mistake. + +It was created by RNAforester configure 1.5, which was +generated by GNU Autoconf 2.59. Invocation command line was + + $ ./configure --prefix=/usr/local --cache-file=/dev/null --srcdir=. + +## --------- ## +## Platform. ## +## --------- ## + +hostname = mcluster02 +uname -m = x86_64 +uname -r = 2.6.9-34.ELsmp +uname -s = Linux +uname -v = #1 SMP Fri Feb 24 16:56:28 EST 2006 + +/usr/bin/uname -p = unknown +/bin/uname -X = unknown + +/bin/arch = x86_64 +/usr/bin/arch -k = unknown +/usr/convex/getsysinfo = unknown +hostinfo = unknown +/bin/machine = unknown +/usr/bin/oslevel = unknown +/bin/universe = unknown + +PATH: /storage/appl/n1ge6u7/bin/lx24-amd64 +PATH: /opt/sun/n1gc/bin +PATH: /usr/local/bin +PATH: /bin +PATH: /usr/bin +PATH: /opt/c3-4/ +PATH: /usr/X11R6/bin +PATH: /usr/local/bin +PATH: /usr/local/bin/X11R5 +PATH: /usr/local/X11R5/bin +PATH: /usr/X11R6/bin +PATH: /home/rabani/Develop/perl/GeneXPress +PATH: /home/rabani/Develop/perl/Genome +PATH: /home/rabani/Develop/perl/Lib +PATH: /home/rabani/Develop/perl/Parsers +PATH: /home/rabani/Develop/perl/RNA +PATH: /home/rabani/Develop/perl/Sequence +PATH: /home/rabani/Develop/perl/System +PATH: /home/rabani/Develop/perl/Web +PATH: /home/rabani/Develop/perl/Web/DataDir +PATH: /home/rabani/Develop/genie_release64/Programs +PATH: /storage/appl/matlab14.3/bin +PATH: /home/rabani + + +## ----------- ## +## Core tests. ## +## ----------- ## + +configure:1369: checking for a BSD-compatible install +configure:1424: result: /usr/bin/install -c +configure:1435: checking whether build environment is sane +configure:1478: result: yes +configure:1543: checking for gawk +configure:1559: found /bin/gawk +configure:1569: result: gawk +configure:1579: checking whether make sets $(MAKE) +configure:1599: result: yes +configure:1823: checking for g++ +configure:1839: found /usr/bin/g++ +configure:1849: result: g++ +configure:1865: checking for C++ compiler version +configure:1868: g++ --version &5 +g++ (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:1871: $? = 0 +configure:1873: g++ -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:1876: $? = 0 +configure:1878: g++ -V &5 +g++: `-V' option must have argument +configure:1881: $? = 1 +configure:1904: checking for C++ compiler default output file name +configure:1907: g++ conftest.cc >&5 +configure:1910: $? = 0 +configure:1956: result: a.out +configure:1961: checking whether the C++ compiler works +configure:1967: ./a.out +configure:1970: $? = 0 +configure:1987: result: yes +configure:1994: checking whether we are cross compiling +configure:1996: result: no +configure:1999: checking for suffix of executables +configure:2001: g++ -o conftest conftest.cc >&5 +configure:2004: $? = 0 +configure:2029: result: +configure:2035: checking for suffix of object files +configure:2056: g++ -c conftest.cc >&5 +configure:2059: $? = 0 +configure:2081: result: o +configure:2085: checking whether we are using the GNU C++ compiler +configure:2109: g++ -c conftest.cc >&5 +configure:2115: $? = 0 +configure:2119: test -z + || test ! -s conftest.err +configure:2122: $? = 0 +configure:2125: test -s conftest.o +configure:2128: $? = 0 +configure:2141: result: yes +configure:2147: checking whether g++ accepts -g +configure:2168: g++ -c -g conftest.cc >&5 +configure:2174: $? = 0 +configure:2178: test -z + || test ! -s conftest.err +configure:2181: $? = 0 +configure:2184: test -s conftest.o +configure:2187: $? = 0 +configure:2198: result: yes +configure:2240: g++ -c -g -O2 conftest.cc >&5 +configure:2246: $? = 0 +configure:2250: test -z + || test ! -s conftest.err +configure:2253: $? = 0 +configure:2256: test -s conftest.o +configure:2259: $? = 0 +configure:2285: g++ -c -g -O2 conftest.cc >&5 +conftest.cc: In function `int main()': +conftest.cc:15: error: `exit' was not declared in this scope +configure:2291: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "RNAforester" +| #define PACKAGE_TARNAME "RNAforester" +| #define PACKAGE_VERSION "1.5" +| #define PACKAGE_STRING "RNAforester 1.5" +| #define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +| #define PACKAGE "RNAforester" +| #define VERSION "1.5" +| /* end confdefs.h. */ +| +| int +| main () +| { +| exit (42); +| ; +| return 0; +| } +configure:2240: g++ -c -g -O2 conftest.cc >&5 +configure:2246: $? = 0 +configure:2250: test -z + || test ! -s conftest.err +configure:2253: $? = 0 +configure:2256: test -s conftest.o +configure:2259: $? = 0 +configure:2285: g++ -c -g -O2 conftest.cc >&5 +configure:2291: $? = 0 +configure:2295: test -z + || test ! -s conftest.err +configure:2298: $? = 0 +configure:2301: test -s conftest.o +configure:2304: $? = 0 +configure:2338: checking for style of include used by make +configure:2366: result: GNU +configure:2394: checking dependency style of g++ +configure:2484: result: gcc3 +configure:2547: checking for gcc +configure:2563: found /usr/bin/gcc +configure:2573: result: gcc +configure:2817: checking for C compiler version +configure:2820: gcc --version &5 +gcc (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:2823: $? = 0 +configure:2825: gcc -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:2828: $? = 0 +configure:2830: gcc -V &5 +gcc: `-V' option must have argument +configure:2833: $? = 1 +configure:2836: checking whether we are using the GNU C compiler +configure:2860: gcc -c conftest.c >&5 +configure:2866: $? = 0 +configure:2870: test -z + || test ! -s conftest.err +configure:2873: $? = 0 +configure:2876: test -s conftest.o +configure:2879: $? = 0 +configure:2892: result: yes +configure:2898: checking whether gcc accepts -g +configure:2919: gcc -c -g conftest.c >&5 +configure:2925: $? = 0 +configure:2929: test -z + || test ! -s conftest.err +configure:2932: $? = 0 +configure:2935: test -s conftest.o +configure:2938: $? = 0 +configure:2949: result: yes +configure:2966: checking for gcc option to accept ANSI C +configure:3036: gcc -c -g -O2 conftest.c >&5 +configure:3042: $? = 0 +configure:3046: test -z + || test ! -s conftest.err +configure:3049: $? = 0 +configure:3052: test -s conftest.o +configure:3055: $? = 0 +configure:3073: result: none needed +configure:3091: gcc -c -g -O2 conftest.c >&5 +conftest.c:2: error: syntax error before "me" +configure:3097: $? = 1 +configure: failed program was: +| #ifndef __cplusplus +| choke me +| #endif +configure:3232: checking dependency style of gcc +configure:3322: result: gcc3 +configure:3364: result: using (to be built) libRNA.a in ../lib +configure:3376: checking for gdImageLine in -lgd +configure:3406: g++ -o conftest -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ -L../../lib conftest.cc -lgd -lRNA >&5 +/usr/bin/ld: cannot find -lRNA +collect2: ld returned 1 exit status +configure:3412: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "RNAforester" +| #define PACKAGE_TARNAME "RNAforester" +| #define PACKAGE_VERSION "1.5" +| #define PACKAGE_STRING "RNAforester 1.5" +| #define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +| #define PACKAGE "RNAforester" +| #define VERSION "1.5" +| #ifdef __cplusplus +| extern "C" void std::exit (int) throw (); using std::exit; +| #endif +| #define HAVE_LIBRNA 1 +| /* end confdefs.h. */ +| +| /* Override any gcc2 internal prototype to avoid an error. */ +| #ifdef __cplusplus +| extern "C" +| #endif +| /* We use char because int might match the return type of a gcc2 +| builtin and then its argument prototype would still apply. */ +| char gdImageLine (); +| int +| main () +| { +| gdImageLine (); +| ; +| return 0; +| } +configure:3438: result: no +configure:3455: checking how to run the C++ preprocessor +configure:3486: g++ -E -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc +configure:3492: $? = 0 +configure:3524: g++ -E -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc +conftest.cc:15:28: ac_nonexistent.h: No such file or directory +configure:3530: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "RNAforester" +| #define PACKAGE_TARNAME "RNAforester" +| #define PACKAGE_VERSION "1.5" +| #define PACKAGE_STRING "RNAforester 1.5" +| #define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +| #define PACKAGE "RNAforester" +| #define VERSION "1.5" +| #ifdef __cplusplus +| extern "C" void std::exit (int) throw (); using std::exit; +| #endif +| #define HAVE_LIBRNA 1 +| /* end confdefs.h. */ +| #include +configure:3569: result: g++ -E +configure:3593: g++ -E -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc +configure:3599: $? = 0 +configure:3631: g++ -E -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc +conftest.cc:15:28: ac_nonexistent.h: No such file or directory +configure:3637: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "RNAforester" +| #define PACKAGE_TARNAME "RNAforester" +| #define PACKAGE_VERSION "1.5" +| #define PACKAGE_STRING "RNAforester 1.5" +| #define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +| #define PACKAGE "RNAforester" +| #define VERSION "1.5" +| #ifdef __cplusplus +| extern "C" void std::exit (int) throw (); using std::exit; +| #endif +| #define HAVE_LIBRNA 1 +| /* end confdefs.h. */ +| #include +configure:3681: checking for egrep +configure:3691: result: grep -E +configure:3696: checking for ANSI C header files +configure:3721: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3727: $? = 0 +configure:3731: test -z + || test ! -s conftest.err +configure:3734: $? = 0 +configure:3737: test -s conftest.o +configure:3740: $? = 0 +configure:3829: g++ -o conftest -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ -L../../lib conftest.cc -lRNA >&5 +/usr/bin/ld: cannot find -lRNA +collect2: ld returned 1 exit status +configure:3832: $? = 1 +configure: program exited with status 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "RNAforester" +| #define PACKAGE_TARNAME "RNAforester" +| #define PACKAGE_VERSION "1.5" +| #define PACKAGE_STRING "RNAforester 1.5" +| #define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +| #define PACKAGE "RNAforester" +| #define VERSION "1.5" +| #ifdef __cplusplus +| extern "C" void std::exit (int) throw (); using std::exit; +| #endif +| #define HAVE_LIBRNA 1 +| /* end confdefs.h. */ +| #include +| #if ((' ' & 0x0FF) == 0x020) +| # define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +| # define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +| #else +| # define ISLOWER(c) (('a' <= (c) && (c) <= 'i') || ('j' <= (c) && (c) <= 'r') || ('s' <= (c) && (c) <= 'z')) +| # define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +| #endif +| +| #define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +| int +| main () +| { +| int i; +| for (i = 0; i < 256; i++) +| if (XOR (islower (i), ISLOWER (i)) +| || toupper (i) != TOUPPER (i)) +| exit(2); +| exit (0); +| } +configure:3852: result: no +configure:3876: checking for sys/types.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for sys/stat.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for stdlib.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for string.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for memory.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for strings.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for inttypes.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for stdint.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3876: checking for unistd.h +configure:3892: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3898: $? = 0 +configure:3902: test -z + || test ! -s conftest.err +configure:3905: $? = 0 +configure:3908: test -s conftest.o +configure:3911: $? = 0 +configure:3922: result: yes +configure:3944: checking g2.h usability +configure:3956: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:3962: $? = 0 +configure:3966: test -z + || test ! -s conftest.err +configure:3969: $? = 0 +configure:3972: test -s conftest.o +configure:3975: $? = 0 +configure:3985: result: yes +configure:3989: checking g2.h presence +configure:3999: g++ -E -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc +configure:4005: $? = 0 +configure:4025: result: yes +configure:4060: checking for g2.h +configure:4067: result: yes +configure:4084: checking for an ANSI C-conforming const +configure:4151: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:4157: $? = 0 +configure:4161: test -z + || test ! -s conftest.err +configure:4164: $? = 0 +configure:4167: test -s conftest.o +configure:4170: $? = 0 +configure:4181: result: yes +configure:4191: checking for inline +configure:4212: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:4218: $? = 0 +configure:4222: test -z + || test ! -s conftest.err +configure:4225: $? = 0 +configure:4228: test -s conftest.o +configure:4231: $? = 0 +configure:4243: result: inline +configure:4262: checking for size_t +configure:4286: g++ -c -g -O2 -Ig2-0.70/src/ -Lg2-0.70/ conftest.cc >&5 +configure:4292: $? = 0 +configure:4296: test -z + || test ! -s conftest.err +configure:4299: $? = 0 +configure:4302: test -s conftest.o +configure:4305: $? = 0 +configure:4316: result: yes +configure:4463: creating ./config.status + +## ---------------------- ## +## Running config.status. ## +## ---------------------- ## + +This file was extended by RNAforester config.status 1.5, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = + CONFIG_HEADERS = + CONFIG_LINKS = + CONFIG_COMMANDS = + $ ./config.status + +on mcluster02 + +config.status:698: creating Makefile +config.status:698: creating src/Makefile +config.status:698: creating man/Makefile +config.status:802: creating config.h +config.status:910: config.h is unchanged +config.status:1090: executing depfiles commands +configure:5803: configuring in g2-0.70 +configure:5920: running /bin/sh './configure' --prefix=/usr/local '--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.' --cache-file=/dev/null --srcdir=. + +## ---------------- ## +## Cache variables. ## +## ---------------- ## + +ac_cv_c_compiler_gnu=yes +ac_cv_c_const=yes +ac_cv_c_inline=inline +ac_cv_cxx_compiler_gnu=yes +ac_cv_env_CC_set= +ac_cv_env_CC_value= +ac_cv_env_CFLAGS_set= +ac_cv_env_CFLAGS_value= +ac_cv_env_CPPFLAGS_set= +ac_cv_env_CPPFLAGS_value= +ac_cv_env_CXXCPP_set= +ac_cv_env_CXXCPP_value= +ac_cv_env_CXXFLAGS_set= +ac_cv_env_CXXFLAGS_value= +ac_cv_env_CXX_set= +ac_cv_env_CXX_value= +ac_cv_env_LDFLAGS_set= +ac_cv_env_LDFLAGS_value= +ac_cv_env_build_alias_set= +ac_cv_env_build_alias_value= +ac_cv_env_host_alias_set= +ac_cv_env_host_alias_value= +ac_cv_env_target_alias_set= +ac_cv_env_target_alias_value= +ac_cv_exeext= +ac_cv_header_g2_h=yes +ac_cv_header_inttypes_h=yes +ac_cv_header_memory_h=yes +ac_cv_header_stdc=no +ac_cv_header_stdint_h=yes +ac_cv_header_stdlib_h=yes +ac_cv_header_string_h=yes +ac_cv_header_strings_h=yes +ac_cv_header_sys_stat_h=yes +ac_cv_header_sys_types_h=yes +ac_cv_header_unistd_h=yes +ac_cv_lib_gd_gdImageLine=no +ac_cv_objext=o +ac_cv_path_install='/usr/bin/install -c' +ac_cv_prog_AWK=gawk +ac_cv_prog_CXXCPP='g++ -E' +ac_cv_prog_ac_ct_CC=gcc +ac_cv_prog_ac_ct_CXX=g++ +ac_cv_prog_cc_g=yes +ac_cv_prog_cc_stdc= +ac_cv_prog_cxx_g=yes +ac_cv_prog_egrep='grep -E' +ac_cv_prog_make_make_set=yes +ac_cv_type_size_t=yes +am_cv_CC_dependencies_compiler_type=gcc3 +am_cv_CXX_dependencies_compiler_type=gcc3 + +## ----------------- ## +## Output variables. ## +## ----------------- ## + +ACLOCAL='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run aclocal-1.9' +AMDEPBACKSLASH='\' +AMDEP_FALSE='#' +AMDEP_TRUE='' +AMTAR='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run tar' +AUTOCONF='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run autoconf' +AUTOHEADER='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run autoheader' +AUTOMAKE='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run automake-1.9' +AWK='gawk' +CC='gcc' +CCDEPMODE='depmode=gcc3' +CFLAGS='-g -O2' +CPPFLAGS=' -I../g2-0.70/include/' +CXX='g++' +CXXCPP='g++ -E' +CXXDEPMODE='depmode=gcc3' +CXXFLAGS='-g -O2' +CYGPATH_W='echo' +DEFS='-DHAVE_CONFIG_H' +DEPDIR='.deps' +ECHO_C='' +ECHO_N='-n' +ECHO_T='' +EGREP='grep -E' +EXEEXT='' +INSTALL_DATA='${INSTALL} -m 644' +INSTALL_PROGRAM='${INSTALL}' +INSTALL_SCRIPT='${INSTALL}' +INSTALL_STRIP_PROGRAM='${SHELL} $(install_sh) -c -s' +LDFLAGS='-L../g2-0.70 -L../../lib ' +LIBOBJS='' +LIBS='-lg2 -lRNA ' +LTLIBOBJS='' +MAKEINFO='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing --run makeinfo' +OBJEXT='o' +PACKAGE='RNAforester' +PACKAGE_BUGREPORT='mhoechsm@techfak.uni-bielefeld.de' +PACKAGE_NAME='RNAforester' +PACKAGE_STRING='RNAforester 1.5' +PACKAGE_TARNAME='RNAforester' +PACKAGE_VERSION='1.5' +PATH_SEPARATOR=':' +SET_MAKE='' +SHELL='/bin/sh' +STRIP='' +VERSION='1.5' +ac_ct_CC='gcc' +ac_ct_CXX='g++' +ac_ct_STRIP='' +am__fastdepCC_FALSE='#' +am__fastdepCC_TRUE='' +am__fastdepCXX_FALSE='#' +am__fastdepCXX_TRUE='' +am__include='include' +am__leading_dot='.' +am__quote='' +am__tar='${AMTAR} chof - "$$tardir"' +am__untar='${AMTAR} xf -' +bindir='${exec_prefix}/bin' +build_alias='' +datadir='${prefix}/share' +exec_prefix='${prefix}' +host_alias='' +includedir='${prefix}/include' +infodir='${prefix}/info' +install_sh='/home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/install-sh' +libdir='${exec_prefix}/lib' +libexecdir='${exec_prefix}/libexec' +localstatedir='${prefix}/var' +mandir='${prefix}/man' +mkdir_p='mkdir -p --' +oldincludedir='/usr/include' +prefix='/usr/local' +program_transform_name='s,x,x,' +sbindir='${exec_prefix}/sbin' +sharedstatedir='${prefix}/com' +subdirs=' g2-0.70' +sysconfdir='${prefix}/etc' +target_alias='' + +## ----------- ## +## confdefs.h. ## +## ----------- ## + +#define HAVE_INTTYPES_H 1 +#define HAVE_LIBG2 1 +#define HAVE_LIBRNA 1 +#define HAVE_MEMORY_H 1 +#define HAVE_STDINT_H 1 +#define HAVE_STDLIB_H 1 +#define HAVE_STRINGS_H 1 +#define HAVE_STRING_H 1 +#define HAVE_SYS_STAT_H 1 +#define HAVE_SYS_TYPES_H 1 +#define HAVE_UNISTD_H 1 +#define PACKAGE "RNAforester" +#define PACKAGE_BUGREPORT "mhoechsm@techfak.uni-bielefeld.de" +#define PACKAGE_NAME "RNAforester" +#define PACKAGE_STRING "RNAforester 1.5" +#define PACKAGE_TARNAME "RNAforester" +#define PACKAGE_VERSION "1.5" +#define VERSION "1.5" +#endif +#ifdef __cplusplus +extern "C" void std::exit (int) throw (); using std::exit; + +configure: exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.status b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.status new file mode 100755 index 00000000..fe67d98c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/config.status @@ -0,0 +1,1181 @@ +#! /bin/sh +# Generated by configure. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=${CONFIG_SHELL-/bin/sh} +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-) + sed '=' <$as_myself | + sed ' + N + s,$,-, + : loop + s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3, + t loop + s,-$,, + s,^['$as_cr_digits']*\n,, + ' >$as_me.lineno && + chmod +x $as_me.lineno || + { { echo "$as_me:$LINENO: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&5 +echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2;} + { (exit 1); exit 1; }; } + + # Don't try to exec as it changes $[0], causing all sort of problems + # (the dirname of $[0] is not the place where we might find the + # original and so on. Autoconf is especially sensible to this). + . ./$as_me.lineno + # Exit status is that of the last command. + exit +} + + +case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in + *c*,-n*) ECHO_N= ECHO_C=' +' ECHO_T=' ' ;; + *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;; + *) ECHO_N= ECHO_C='\c' ECHO_T= ;; +esac + +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +rm -f conf$$ conf$$.exe conf$$.file +echo >conf$$.file +if ln -s conf$$.file conf$$ 2>/dev/null; then + # We could just check for DJGPP; but this test a) works b) is more generic + # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04). + if test -f conf$$.exe; then + # Don't use ln at all; we don't have any links + as_ln_s='cp -p' + else + as_ln_s='ln -s' + fi +elif ln conf$$.file conf$$ 2>/dev/null; then + as_ln_s=ln +else + as_ln_s='cp -p' +fi +rm -f conf$$ conf$$.exe conf$$.file + +if mkdir -p . 2>/dev/null; then + as_mkdir_p=: +else + test -d ./-p && rmdir ./-p + as_mkdir_p=false +fi + +as_executable_p="test -f" + +# Sed expression to map a string onto a valid CPP name. +as_tr_cpp="eval sed 'y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g'" + +# Sed expression to map a string onto a valid variable name. +as_tr_sh="eval sed 'y%*+%pp%;s%[^_$as_cr_alnum]%_%g'" + + +# IFS +# We need space, tab and new line, in precisely that order. +as_nl=' +' +IFS=" $as_nl" + +# CDPATH. +$as_unset CDPATH + +exec 6>&1 + +# Open the log real soon, to keep \$[0] and so on meaningful, and to +# report actual input values of CONFIG_FILES etc. instead of their +# values after options handling. 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Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +config_files=" Makefile src/Makefile man/Makefile" +config_headers=" config.h" +config_commands=" depfiles" + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +ac_cs_version="\ +RNAforester config.status 1.5 +configured by ./configure, generated by GNU Autoconf 2.59, + with options \"'--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.'\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=. +INSTALL="/usr/bin/install -c" +# If no file are specified by the user, then we need to provide default +# value. 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Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. 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See below for descriptions of some of the useful variables. + +Defaults for the options are specified in brackets. + +Configuration: + -h, --help display this help and exit + --help=short display options specific to this package + --help=recursive display the short help of all the included packages + -V, --version display version information and exit + -q, --quiet, --silent do not print \`checking...' messages + --cache-file=FILE cache test results in FILE [disabled] + -C, --config-cache alias for \`--cache-file=config.cache' + -n, --no-create do not create output files + --srcdir=DIR find the sources in DIR [configure dir or \`..'] + +_ACEOF + + cat <<_ACEOF +Installation directories: + --prefix=PREFIX install architecture-independent files in PREFIX + [$ac_default_prefix] + --exec-prefix=EPREFIX install architecture-dependent files in EPREFIX + [PREFIX] + +By default, \`make install' will install all the files in +\`$ac_default_prefix/bin', \`$ac_default_prefix/lib' etc. You can specify +an installation prefix other than \`$ac_default_prefix' using \`--prefix', +for instance \`--prefix=\$HOME'. + +For better control, use the options below. + +Fine tuning of the installation directories: + --bindir=DIR user executables [EPREFIX/bin] + --sbindir=DIR system admin executables [EPREFIX/sbin] + --libexecdir=DIR program executables [EPREFIX/libexec] + --datadir=DIR read-only architecture-independent data [PREFIX/share] + --sysconfdir=DIR read-only single-machine data [PREFIX/etc] + --sharedstatedir=DIR modifiable architecture-independent data [PREFIX/com] + --localstatedir=DIR modifiable single-machine data [PREFIX/var] + --libdir=DIR object code libraries [EPREFIX/lib] + --includedir=DIR C header files [PREFIX/include] + --oldincludedir=DIR C header files for non-gcc [/usr/include] + --infodir=DIR info documentation [PREFIX/info] + --mandir=DIR man documentation [PREFIX/man] +_ACEOF + + cat <<\_ACEOF + +Program names: + --program-prefix=PREFIX prepend PREFIX to installed program names + --program-suffix=SUFFIX append SUFFIX to installed program names + --program-transform-name=PROGRAM run sed PROGRAM on installed program names +_ACEOF +fi + +if test -n "$ac_init_help"; then + case $ac_init_help in + short | recursive ) echo "Configuration of RNAforester 1.5:";; + esac + cat <<\_ACEOF + +Optional Features: + --disable-FEATURE do not include FEATURE (same as --enable-FEATURE=no) + --enable-FEATURE[=ARG] include FEATURE [ARG=yes] + --disable-dependency-tracking speeds up one-time build + --enable-dependency-tracking do not reject slow dependency extractors + +Optional Packages: + --with-PACKAGE[=ARG] use PACKAGE [ARG=yes] + --without-PACKAGE do not use PACKAGE (same as --with-PACKAGE=no) +--with-ViennaRNA-lib where to search for libRNA.a + +Some influential environment variables: + CXX C++ compiler command + CXXFLAGS C++ compiler flags + LDFLAGS linker flags, e.g. -L if you have libraries in a + nonstandard directory + CPPFLAGS C/C++ preprocessor flags, e.g. -I if you have + headers in a nonstandard directory + CC C compiler command + CFLAGS C compiler flags + CXXCPP C++ preprocessor + +Use these variables to override the choices made by `configure' or to help +it to find libraries and programs with nonstandard names/locations. + +Report bugs to . +_ACEOF +fi + +if test "$ac_init_help" = "recursive"; then + # If there are subdirs, report their specific --help. + ac_popdir=`pwd` + for ac_dir in : $ac_subdirs_all; do test "x$ac_dir" = x: && continue + test -d $ac_dir || continue + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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Use of quotes ensures accuracy. + *) ac_configure_args="$ac_configure_args '$ac_arg'" ;; + esac + fi +done +if $ac_cache_corrupted; then + { echo "$as_me:$LINENO: error: changes in the environment can compromise the build" >&5 +echo "$as_me: error: changes in the environment can compromise the build" >&2;} + { { echo "$as_me:$LINENO: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&5 +echo "$as_me: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + + + + + + + + + + + + + + + + + + + + + + + + + + + + +am__api_version="1.9" +ac_aux_dir= +for ac_dir in $srcdir $srcdir/.. $srcdir/../..; do + if test -f $ac_dir/install-sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install-sh -c" + break + elif test -f $ac_dir/install.sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install.sh -c" + break + elif test -f $ac_dir/shtool; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/shtool install -c" + break + fi +done +if test -z "$ac_aux_dir"; then + { { echo "$as_me:$LINENO: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&5 +echo "$as_me: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&2;} + { (exit 1); exit 1; }; } +fi +ac_config_guess="$SHELL $ac_aux_dir/config.guess" +ac_config_sub="$SHELL $ac_aux_dir/config.sub" +ac_configure="$SHELL $ac_aux_dir/configure" # This should be Cygnus configure. + +# Find a good install program. We prefer a C program (faster), +# so one script is as good as another. But avoid the broken or +# incompatible versions: +# SysV /etc/install, /usr/sbin/install +# SunOS /usr/etc/install +# IRIX /sbin/install +# AIX /bin/install +# AmigaOS /C/install, which installs bootblocks on floppy discs +# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag +# AFS /usr/afsws/bin/install, which mishandles nonexistent args +# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff" +# OS/2's system install, which has a completely different semantic +# ./install, which can be erroneously created by make from ./install.sh. +echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5 +echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6 +if test -z "$INSTALL"; then +if test "${ac_cv_path_install+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + # Account for people who put trailing slashes in PATH elements. +case $as_dir/ in + ./ | .// | /cC/* | \ + /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \ + ?:\\/os2\\/install\\/* | ?:\\/OS2\\/INSTALL\\/* | \ + /usr/ucb/* ) ;; + *) + # OSF1 and SCO ODT 3.0 have their own names for install. + # Don't use installbsd from OSF since it installs stuff as root + # by default. + for ac_prog in ginstall scoinst install; do + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then + if test $ac_prog = install && + grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # AIX install. It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +echo "$as_me:$LINENO: checking whether build environment is sane" >&5 +echo $ECHO_N "checking whether build environment is sane... $ECHO_C" >&6 +# Just in case +sleep 1 +echo timestamp > conftest.file +# Do `set' in a subshell so we don't clobber the current shell's +# arguments. Must try -L first in case configure is actually a +# symlink; some systems play weird games with the mod time of symlinks +# (eg FreeBSD returns the mod time of the symlink's containing +# directory). +if ( + set X `ls -Lt $srcdir/configure conftest.file 2> /dev/null` + if test "$*" = "X"; then + # -L didn't work. + set X `ls -t $srcdir/configure conftest.file` + fi + rm -f conftest.file + if test "$*" != "X $srcdir/configure conftest.file" \ + && test "$*" != "X conftest.file $srcdir/configure"; then + + # If neither matched, then we have a broken ls. This can happen + # if, for instance, CONFIG_SHELL is bash and it inherits a + # broken ls alias from the environment. This has actually + # happened. Such a system could not be considered "sane". + { { echo "$as_me:$LINENO: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&5 +echo "$as_me: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&2;} + { (exit 1); exit 1; }; } + fi + + test "$2" = conftest.file + ) +then + # Ok. + : +else + { { echo "$as_me:$LINENO: error: newly created file is older than distributed files! +Check your system clock" >&5 +echo "$as_me: error: newly created file is older than distributed files! +Check your system clock" >&2;} + { (exit 1); exit 1; }; } +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 +test "$program_prefix" != NONE && + program_transform_name="s,^,$program_prefix,;$program_transform_name" +# Use a double $ so make ignores it. +test "$program_suffix" != NONE && + program_transform_name="s,\$,$program_suffix,;$program_transform_name" +# Double any \ or $. echo might interpret backslashes. +# By default was `s,x,x', remove it if useless. +cat <<\_ACEOF >conftest.sed +s/[\\$]/&&/g;s/;s,x,x,$// +_ACEOF +program_transform_name=`echo $program_transform_name | sed -f conftest.sed` +rm conftest.sed + +# expand $ac_aux_dir to an absolute path +am_aux_dir=`cd $ac_aux_dir && pwd` + +test x"${MISSING+set}" = xset || MISSING="\${SHELL} $am_aux_dir/missing" +# Use eval to expand $SHELL +if eval "$MISSING --run true"; then + am_missing_run="$MISSING --run " +else + am_missing_run= + { echo "$as_me:$LINENO: WARNING: \`missing' script is too old or missing" >&5 +echo "$as_me: WARNING: \`missing' script is too old or missing" >&2;} +fi + +if mkdir -p --version . >/dev/null 2>&1 && test ! -d ./--version; then + # We used to keeping the `.' as first argument, in order to + # allow $(mkdir_p) to be used without argument. As in + # $(mkdir_p) $(somedir) + # where $(somedir) is conditionally defined. However this is wrong + # for two reasons: + # 1. if the package is installed by a user who cannot write `.' + # make install will fail, + # 2. the above comment should most certainly read + # $(mkdir_p) $(DESTDIR)$(somedir) + # so it does not work when $(somedir) is undefined and + # $(DESTDIR) is not. + # To support the latter case, we have to write + # test -z "$(somedir)" || $(mkdir_p) $(DESTDIR)$(somedir), + # so the `.' trick is pointless. + mkdir_p='mkdir -p --' +else + # On NextStep and OpenStep, the `mkdir' command does not + # recognize any option. It will interpret all options as + # directories to create, and then abort because `.' already + # exists. + for d in ./-p ./--version; + do + test -d $d && rmdir $d + done + # $(mkinstalldirs) is defined by Automake if mkinstalldirs exists. + if test -f "$ac_aux_dir/mkinstalldirs"; then + mkdir_p='$(mkinstalldirs)' + else + mkdir_p='$(install_sh) -d' + fi +fi + +for ac_prog in gawk mawk nawk awk +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_AWK+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$AWK"; then + ac_cv_prog_AWK="$AWK" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_AWK="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +AWK=$ac_cv_prog_AWK +if test -n "$AWK"; then + echo "$as_me:$LINENO: result: $AWK" >&5 +echo "${ECHO_T}$AWK" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$AWK" && break +done + +echo "$as_me:$LINENO: checking whether ${MAKE-make} sets \$(MAKE)" >&5 +echo $ECHO_N "checking whether ${MAKE-make} sets \$(MAKE)... $ECHO_C" >&6 +set dummy ${MAKE-make}; ac_make=`echo "$2" | sed 'y,:./+-,___p_,'` +if eval "test \"\${ac_cv_prog_make_${ac_make}_set+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.make <<\_ACEOF +all: + @echo 'ac_maketemp="$(MAKE)"' +_ACEOF +# GNU make sometimes prints "make[1]: Entering...", which would confuse us. +eval `${MAKE-make} -f conftest.make 2>/dev/null | grep temp=` +if test -n "$ac_maketemp"; then + eval ac_cv_prog_make_${ac_make}_set=yes +else + eval ac_cv_prog_make_${ac_make}_set=no +fi +rm -f conftest.make +fi +if eval "test \"`echo '$ac_cv_prog_make_'${ac_make}_set`\" = yes"; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + SET_MAKE= +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + SET_MAKE="MAKE=${MAKE-make}" +fi + +rm -rf .tst 2>/dev/null +mkdir .tst 2>/dev/null +if test -d .tst; then + am__leading_dot=. +else + am__leading_dot=_ +fi +rmdir .tst 2>/dev/null + +# test to see if srcdir already configured +if test "`cd $srcdir && pwd`" != "`pwd`" && + test -f $srcdir/config.status; then + { { echo "$as_me:$LINENO: error: source directory already configured; run \"make distclean\" there first" >&5 +echo "$as_me: error: source directory already configured; run \"make distclean\" there first" >&2;} + { (exit 1); exit 1; }; } +fi + +# test whether we have cygpath +if test -z "$CYGPATH_W"; then + if (cygpath --version) >/dev/null 2>/dev/null; then + CYGPATH_W='cygpath -w' + else + CYGPATH_W=echo + fi +fi + + +# Define the identity of the package. + PACKAGE='RNAforester' + VERSION='1.5' + + +cat >>confdefs.h <<_ACEOF +#define PACKAGE "$PACKAGE" +_ACEOF + + +cat >>confdefs.h <<_ACEOF +#define VERSION "$VERSION" +_ACEOF + +# Some tools Automake needs. + +ACLOCAL=${ACLOCAL-"${am_missing_run}aclocal-${am__api_version}"} + + +AUTOCONF=${AUTOCONF-"${am_missing_run}autoconf"} + + +AUTOMAKE=${AUTOMAKE-"${am_missing_run}automake-${am__api_version}"} + + +AUTOHEADER=${AUTOHEADER-"${am_missing_run}autoheader"} + + +MAKEINFO=${MAKEINFO-"${am_missing_run}makeinfo"} + +install_sh=${install_sh-"$am_aux_dir/install-sh"} + +# Installed binaries are usually stripped using `strip' when the user +# run `make install-strip'. However `strip' might not be the right +# tool to use in cross-compilation environments, therefore Automake +# will honor the `STRIP' environment variable to overrule this program. +if test "$cross_compiling" != no; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}strip", so it can be a program name with args. +set dummy ${ac_tool_prefix}strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$STRIP"; then + ac_cv_prog_STRIP="$STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_STRIP="${ac_tool_prefix}strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +STRIP=$ac_cv_prog_STRIP +if test -n "$STRIP"; then + echo "$as_me:$LINENO: result: $STRIP" >&5 +echo "${ECHO_T}$STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_STRIP"; then + ac_ct_STRIP=$STRIP + # Extract the first word of "strip", so it can be a program name with args. +set dummy strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_STRIP"; then + ac_cv_prog_ac_ct_STRIP="$ac_ct_STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_STRIP="strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_STRIP" && ac_cv_prog_ac_ct_STRIP=":" +fi +fi +ac_ct_STRIP=$ac_cv_prog_ac_ct_STRIP +if test -n "$ac_ct_STRIP"; then + echo "$as_me:$LINENO: result: $ac_ct_STRIP" >&5 +echo "${ECHO_T}$ac_ct_STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + STRIP=$ac_ct_STRIP +else + STRIP="$ac_cv_prog_STRIP" +fi + +fi +INSTALL_STRIP_PROGRAM="\${SHELL} \$(install_sh) -c -s" + +# We need awk for the "check" target. The system "awk" is bad on +# some platforms. +# Always define AMTAR for backward compatibility. + +AMTAR=${AMTAR-"${am_missing_run}tar"} + +am__tar='${AMTAR} chof - "$$tardir"'; am__untar='${AMTAR} xf -' + + + + + + + ac_config_headers="$ac_config_headers config.h" + + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu +if test -n "$ac_tool_prefix"; then + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CXX"; then + ac_cv_prog_CXX="$CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CXX="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CXX=$ac_cv_prog_CXX +if test -n "$CXX"; then + echo "$as_me:$LINENO: result: $CXX" >&5 +echo "${ECHO_T}$CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CXX" && break + done +fi +if test -z "$CXX"; then + ac_ct_CXX=$CXX + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CXX"; then + ac_cv_prog_ac_ct_CXX="$ac_ct_CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CXX="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CXX=$ac_cv_prog_ac_ct_CXX +if test -n "$ac_ct_CXX"; then + echo "$as_me:$LINENO: result: $ac_ct_CXX" >&5 +echo "${ECHO_T}$ac_ct_CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CXX" && break +done +test -n "$ac_ct_CXX" || ac_ct_CXX="g++" + + CXX=$ac_ct_CXX +fi + + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C++ compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files a.out a.exe b.out" +# Try to create an executable without -o first, disregard a.out. +# It will help us diagnose broken compilers, and finding out an intuition +# of exeext. +echo "$as_me:$LINENO: checking for C++ compiler default output file name" >&5 +echo $ECHO_N "checking for C++ compiler default output file name... $ECHO_C" >&6 +ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'` +if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5 + (eval $ac_link_default) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # Find the output, starting from the most likely. This scheme is +# not robust to junk in `.', hence go to wildcards (a.*) only as a last +# resort. + +# Be careful to initialize this variable, since it used to be cached. +# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile. +ac_cv_exeext= +# b.out is created by i960 compilers. +for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out +do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) + ;; + conftest.$ac_ext ) + # This is the source file. + ;; + [ab].out ) + # We found the default executable, but exeext='' is most + # certainly right. + break;; + *.* ) + ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + # FIXME: I believe we export ac_cv_exeext for Libtool, + # but it would be cool to find out if it's true. Does anybody + # maintain Libtool? --akim. + export ac_cv_exeext + break;; + * ) + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: C++ compiler cannot create executables +See \`config.log' for more details." >&5 +echo "$as_me: error: C++ compiler cannot create executables +See \`config.log' for more details." >&2;} + { (exit 77); exit 77; }; } +fi + +ac_exeext=$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_file" >&5 +echo "${ECHO_T}$ac_file" >&6 + +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether the C++ compiler works" >&5 +echo $ECHO_N "checking whether the C++ compiler works... $ECHO_C" >&6 +# FIXME: These cross compiler hacks should be removed for Autoconf 3.0 +# If not cross compiling, check that we can run a simple program. +if test "$cross_compiling" != yes; then + if { ac_try='./$ac_file' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + cross_compiling=no + else + if test "$cross_compiling" = maybe; then + cross_compiling=yes + else + { { echo "$as_me:$LINENO: error: cannot run C++ compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot run C++ compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + fi + fi +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +rm -f a.out a.exe conftest$ac_cv_exeext b.out +ac_clean_files=$ac_clean_files_save +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether we are cross compiling" >&5 +echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6 +echo "$as_me:$LINENO: result: $cross_compiling" >&5 +echo "${ECHO_T}$cross_compiling" >&6 + +echo "$as_me:$LINENO: checking for suffix of executables" >&5 +echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6 +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # If both `conftest.exe' and `conftest' are `present' (well, observable) +# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will +# work properly (i.e., refer to `conftest.exe'), while it won't with +# `rm'. +for ac_file in conftest.exe conftest conftest.*; do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;; + *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + export ac_cv_exeext + break;; + * ) break;; + esac +done +else + { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5 +echo "${ECHO_T}$ac_cv_exeext" >&6 + +rm -f conftest.$ac_ext +EXEEXT=$ac_cv_exeext +ac_exeext=$EXEEXT +echo "$as_me:$LINENO: checking for suffix of object files" >&5 +echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6 +if test "${ac_cv_objext+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.o conftest.obj +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;; + *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'` + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest.$ac_cv_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_objext" >&5 +echo "${ECHO_T}$ac_cv_objext" >&6 +OBJEXT=$ac_cv_objext +ac_objext=$OBJEXT +echo "$as_me:$LINENO: checking whether we are using the GNU C++ compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C++ compiler... $ECHO_C" >&6 +if test "${ac_cv_cxx_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_cxx_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_cxx_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_cxx_compiler_gnu" >&6 +GXX=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CXXFLAGS=${CXXFLAGS+set} +ac_save_CXXFLAGS=$CXXFLAGS +CXXFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CXX accepts -g" >&5 +echo $ECHO_N "checking whether $CXX accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cxx_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cxx_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cxx_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cxx_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cxx_g" >&6 +if test "$ac_test_CXXFLAGS" = set; then + CXXFLAGS=$ac_save_CXXFLAGS +elif test $ac_cv_prog_cxx_g = yes; then + if test "$GXX" = yes; then + CXXFLAGS="-g -O2" + else + CXXFLAGS="-g" + fi +else + if test "$GXX" = yes; then + CXXFLAGS="-O2" + else + CXXFLAGS= + fi +fi +for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +DEPDIR="${am__leading_dot}deps" + + ac_config_commands="$ac_config_commands depfiles" + + +am_make=${MAKE-make} +cat > confinc << 'END' +am__doit: + @echo done +.PHONY: am__doit +END +# If we don't find an include directive, just comment out the code. +echo "$as_me:$LINENO: checking for style of include used by $am_make" >&5 +echo $ECHO_N "checking for style of include used by $am_make... $ECHO_C" >&6 +am__include="#" +am__quote= +_am_result=none +# First try GNU make style include. +echo "include confinc" > confmf +# We grep out `Entering directory' and `Leaving directory' +# messages which can occur if `w' ends up in MAKEFLAGS. +# In particular we don't look at `^make:' because GNU make might +# be invoked under some other name (usually "gmake"), in which +# case it prints its new name instead of `make'. +if test "`$am_make -s -f confmf 2> /dev/null | grep -v 'ing directory'`" = "done"; then + am__include=include + am__quote= + _am_result=GNU +fi +# Now try BSD make style include. +if test "$am__include" = "#"; then + echo '.include "confinc"' > confmf + if test "`$am_make -s -f confmf 2> /dev/null`" = "done"; then + am__include=.include + am__quote="\"" + _am_result=BSD + fi +fi + + +echo "$as_me:$LINENO: result: $_am_result" >&5 +echo "${ECHO_T}$_am_result" >&6 +rm -f confinc confmf + +# Check whether --enable-dependency-tracking or --disable-dependency-tracking was given. +if test "${enable_dependency_tracking+set}" = set; then + enableval="$enable_dependency_tracking" + +fi; +if test "x$enable_dependency_tracking" != xno; then + am_depcomp="$ac_aux_dir/depcomp" + AMDEPBACKSLASH='\' +fi + + +if test "x$enable_dependency_tracking" != xno; then + AMDEP_TRUE= + AMDEP_FALSE='#' +else + AMDEP_TRUE='#' + AMDEP_FALSE= +fi + + + + +depcc="$CXX" am_compiler_list= + +echo "$as_me:$LINENO: checking dependency style of $depcc" >&5 +echo $ECHO_N "checking dependency style of $depcc... $ECHO_C" >&6 +if test "${am_cv_CXX_dependencies_compiler_type+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then + # We make a subdir and do the tests there. Otherwise we can end up + # making bogus files that we don't know about and never remove. For + # instance it was reported that on HP-UX the gcc test will end up + # making a dummy file named `D' -- because `-MD' means `put the output + # in D'. + mkdir conftest.dir + # Copy depcomp to subdir because otherwise we won't find it if we're + # using a relative directory. + cp "$am_depcomp" conftest.dir + cd conftest.dir + # We will build objects and dependencies in a subdirectory because + # it helps to detect inapplicable dependency modes. For instance + # both Tru64's cc and ICC support -MD to output dependencies as a + # side effect of compilation, but ICC will put the dependencies in + # the current directory while Tru64 will put them in the object + # directory. + mkdir sub + + am_cv_CXX_dependencies_compiler_type=none + if test "$am_compiler_list" = ""; then + am_compiler_list=`sed -n 's/^#*\([a-zA-Z0-9]*\))$/\1/p' < ./depcomp` + fi + for depmode in $am_compiler_list; do + # Setup a source with many dependencies, because some compilers + # like to wrap large dependency lists on column 80 (with \), and + # we should not choose a depcomp mode which is confused by this. + # + # We need to recreate these files for each test, as the compiler may + # overwrite some of them when testing with obscure command lines. + # This happens at least with the AIX C compiler. + : > sub/conftest.c + for i in 1 2 3 4 5 6; do + echo '#include "conftst'$i'.h"' >> sub/conftest.c + # Using `: > sub/conftst$i.h' creates only sub/conftst1.h with + # Solaris 8's {/usr,}/bin/sh. + touch sub/conftst$i.h + done + echo "${am__include} ${am__quote}sub/conftest.Po${am__quote}" > confmf + + case $depmode in + nosideeffect) + # after this tag, mechanisms are not by side-effect, so they'll + # only be used when explicitly requested + if test "x$enable_dependency_tracking" = xyes; then + continue + else + break + fi + ;; + none) break ;; + esac + # We check with `-c' and `-o' for the sake of the "dashmstdout" + # mode. It turns out that the SunPro C++ compiler does not properly + # handle `-M -o', and we need to detect this. + if depmode=$depmode \ + source=sub/conftest.c object=sub/conftest.${OBJEXT-o} \ + depfile=sub/conftest.Po tmpdepfile=sub/conftest.TPo \ + $SHELL ./depcomp $depcc -c -o sub/conftest.${OBJEXT-o} sub/conftest.c \ + >/dev/null 2>conftest.err && + grep sub/conftst6.h sub/conftest.Po > /dev/null 2>&1 && + grep sub/conftest.${OBJEXT-o} sub/conftest.Po > /dev/null 2>&1 && + ${MAKE-make} -s -f confmf > /dev/null 2>&1; then + # icc doesn't choke on unknown options, it will just issue warnings + # or remarks (even with -Werror). So we grep stderr for any message + # that says an option was ignored or not supported. + # When given -MP, icc 7.0 and 7.1 complain thusly: + # icc: Command line warning: ignoring option '-M'; no argument required + # The diagnosis changed in icc 8.0: + # icc: Command line remark: option '-MP' not supported + if (grep 'ignoring option' conftest.err || + grep 'not supported' conftest.err) >/dev/null 2>&1; then :; else + am_cv_CXX_dependencies_compiler_type=$depmode + break + fi + fi + done + + cd .. + rm -rf conftest.dir +else + am_cv_CXX_dependencies_compiler_type=none +fi + +fi +echo "$as_me:$LINENO: result: $am_cv_CXX_dependencies_compiler_type" >&5 +echo "${ECHO_T}$am_cv_CXX_dependencies_compiler_type" >&6 +CXXDEPMODE=depmode=$am_cv_CXX_dependencies_compiler_type + + + +if + test "x$enable_dependency_tracking" != xno \ + && test "$am_cv_CXX_dependencies_compiler_type" = gcc3; then + am__fastdepCXX_TRUE= + am__fastdepCXX_FALSE='#' +else + am__fastdepCXX_TRUE='#' + am__fastdepCXX_FALSE= +fi + + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args. +set dummy ${ac_tool_prefix}gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "gcc", so it can be a program name with args. +set dummy gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args. +set dummy ${ac_tool_prefix}cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +fi +if test -z "$CC"; then + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else + ac_prog_rejected=no +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then + ac_prog_rejected=yes + continue + fi + ac_cv_prog_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +if test $ac_prog_rejected = yes; then + # We found a bogon in the path, so make sure we never use it. + set dummy $ac_cv_prog_CC + shift + if test $# != 0; then + # We chose a different compiler from the bogus one. + # However, it has the same basename, so the bogon will be chosen + # first if we set CC to just the basename; use the full file name. + shift + ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@" + fi +fi +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + for ac_prog in cl + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CC" && break + done +fi +if test -z "$CC"; then + ac_ct_CC=$CC + for ac_prog in cl +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CC" && break +done + + CC=$ac_ct_CC +fi + +fi + + +test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&5 +echo "$as_me: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6 +if test "${ac_cv_c_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_c_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6 +GCC=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CFLAGS=${CFLAGS+set} +ac_save_CFLAGS=$CFLAGS +CFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5 +echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cc_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_g" >&6 +if test "$ac_test_CFLAGS" = set; then + CFLAGS=$ac_save_CFLAGS +elif test $ac_cv_prog_cc_g = yes; then + if test "$GCC" = yes; then + CFLAGS="-g -O2" + else + CFLAGS="-g" + fi +else + if test "$GCC" = yes; then + CFLAGS="-O2" + else + CFLAGS= + fi +fi +echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5 +echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_prog_cc_stdc=no +ac_save_CC=$CC +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include +/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */ +struct buf { int x; }; +FILE * (*rcsopen) (struct buf *, struct stat *, int); +static char *e (p, i) + char **p; + int i; +{ + return p[i]; +} +static char *f (char * (*g) (char **, int), char **p, ...) +{ + char *s; + va_list v; + va_start (v,p); + s = g (p, va_arg (v,int)); + va_end (v); + return s; +} + +/* OSF 4.0 Compaq cc is some sort of almost-ANSI by default. It has + function prototypes and stuff, but not '\xHH' hex character constants. + These don't provoke an error unfortunately, instead are silently treated + as 'x'. The following induces an error, until -std1 is added to get + proper ANSI mode. Curiously '\x00'!='x' always comes out true, for an + array size at least. It's necessary to write '\x00'==0 to get something + that's true only with -std1. */ +int osf4_cc_array ['\x00' == 0 ? 1 : -1]; + +int test (int i, double x); +struct s1 {int (*f) (int a);}; +struct s2 {int (*f) (double a);}; +int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int); +int argc; +char **argv; +int +main () +{ +return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1]; + ; + return 0; +} +_ACEOF +# Don't try gcc -ansi; that turns off useful extensions and +# breaks some systems' header files. +# AIX -qlanglvl=ansi +# Ultrix and OSF/1 -std1 +# HP-UX 10.20 and later -Ae +# HP-UX older versions -Aa -D_HPUX_SOURCE +# SVR4 -Xc -D__EXTENSIONS__ +for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__" +do + CC="$ac_save_CC $ac_arg" + rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_stdc=$ac_arg +break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext +done +rm -f conftest.$ac_ext conftest.$ac_objext +CC=$ac_save_CC + +fi + +case "x$ac_cv_prog_cc_stdc" in + x|xno) + echo "$as_me:$LINENO: result: none needed" >&5 +echo "${ECHO_T}none needed" >&6 ;; + *) + echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6 + CC="$CC $ac_cv_prog_cc_stdc" ;; +esac + +# Some people use a C++ compiler to compile C. Since we use `exit', +# in C++ we need to declare it. In case someone uses the same compiler +# for both compiling C and C++ we need to have the C++ compiler decide +# the declaration of exit, since it's the most demanding environment. +cat >conftest.$ac_ext <<_ACEOF +#ifndef __cplusplus + choke me +#endif +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +depcc="$CC" am_compiler_list= + +echo "$as_me:$LINENO: checking dependency style of $depcc" >&5 +echo $ECHO_N "checking dependency style of $depcc... $ECHO_C" >&6 +if test "${am_cv_CC_dependencies_compiler_type+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then + # We make a subdir and do the tests there. Otherwise we can end up + # making bogus files that we don't know about and never remove. For + # instance it was reported that on HP-UX the gcc test will end up + # making a dummy file named `D' -- because `-MD' means `put the output + # in D'. + mkdir conftest.dir + # Copy depcomp to subdir because otherwise we won't find it if we're + # using a relative directory. + cp "$am_depcomp" conftest.dir + cd conftest.dir + # We will build objects and dependencies in a subdirectory because + # it helps to detect inapplicable dependency modes. For instance + # both Tru64's cc and ICC support -MD to output dependencies as a + # side effect of compilation, but ICC will put the dependencies in + # the current directory while Tru64 will put them in the object + # directory. + mkdir sub + + am_cv_CC_dependencies_compiler_type=none + if test "$am_compiler_list" = ""; then + am_compiler_list=`sed -n 's/^#*\([a-zA-Z0-9]*\))$/\1/p' < ./depcomp` + fi + for depmode in $am_compiler_list; do + # Setup a source with many dependencies, because some compilers + # like to wrap large dependency lists on column 80 (with \), and + # we should not choose a depcomp mode which is confused by this. + # + # We need to recreate these files for each test, as the compiler may + # overwrite some of them when testing with obscure command lines. + # This happens at least with the AIX C compiler. + : > sub/conftest.c + for i in 1 2 3 4 5 6; do + echo '#include "conftst'$i'.h"' >> sub/conftest.c + # Using `: > sub/conftst$i.h' creates only sub/conftst1.h with + # Solaris 8's {/usr,}/bin/sh. + touch sub/conftst$i.h + done + echo "${am__include} ${am__quote}sub/conftest.Po${am__quote}" > confmf + + case $depmode in + nosideeffect) + # after this tag, mechanisms are not by side-effect, so they'll + # only be used when explicitly requested + if test "x$enable_dependency_tracking" = xyes; then + continue + else + break + fi + ;; + none) break ;; + esac + # We check with `-c' and `-o' for the sake of the "dashmstdout" + # mode. It turns out that the SunPro C++ compiler does not properly + # handle `-M -o', and we need to detect this. + if depmode=$depmode \ + source=sub/conftest.c object=sub/conftest.${OBJEXT-o} \ + depfile=sub/conftest.Po tmpdepfile=sub/conftest.TPo \ + $SHELL ./depcomp $depcc -c -o sub/conftest.${OBJEXT-o} sub/conftest.c \ + >/dev/null 2>conftest.err && + grep sub/conftst6.h sub/conftest.Po > /dev/null 2>&1 && + grep sub/conftest.${OBJEXT-o} sub/conftest.Po > /dev/null 2>&1 && + ${MAKE-make} -s -f confmf > /dev/null 2>&1; then + # icc doesn't choke on unknown options, it will just issue warnings + # or remarks (even with -Werror). So we grep stderr for any message + # that says an option was ignored or not supported. + # When given -MP, icc 7.0 and 7.1 complain thusly: + # icc: Command line warning: ignoring option '-M'; no argument required + # The diagnosis changed in icc 8.0: + # icc: Command line remark: option '-MP' not supported + if (grep 'ignoring option' conftest.err || + grep 'not supported' conftest.err) >/dev/null 2>&1; then :; else + am_cv_CC_dependencies_compiler_type=$depmode + break + fi + fi + done + + cd .. + rm -rf conftest.dir +else + am_cv_CC_dependencies_compiler_type=none +fi + +fi +echo "$as_me:$LINENO: result: $am_cv_CC_dependencies_compiler_type" >&5 +echo "${ECHO_T}$am_cv_CC_dependencies_compiler_type" >&6 +CCDEPMODE=depmode=$am_cv_CC_dependencies_compiler_type + + + +if + test "x$enable_dependency_tracking" != xno \ + && test "$am_cv_CC_dependencies_compiler_type" = gcc3; then + am__fastdepCC_TRUE= + am__fastdepCC_FALSE='#' +else + am__fastdepCC_TRUE='#' + am__fastdepCC_FALSE= +fi + + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu + + + + +# Check whether --with-ViennaRNA-lib or --without-ViennaRNA-lib was given. +if test "${with_ViennaRNA_lib+set}" = set; then + withval="$with_ViennaRNA_lib" + LIBS="$withval/libRNA.a ${LIBS}" && +cat >>confdefs.h <<\_ACEOF +#define HAVE_LIBRNA 1 +_ACEOF + +else + LDFLAGS="-L../../lib ${LDFLAGS}" + if test -r "../lib/fold.c"; then + cat >>confdefs.h <<\_ACEOF +#define HAVE_LIBRNA 1 +_ACEOF + + LIBS="-lRNA ${LIBS}" + echo "$as_me:$LINENO: result: using (to be built) libRNA.a in ../lib" >&5 +echo "${ECHO_T}using (to be built) libRNA.a in ../lib" >&6 + fi + +fi; + +save_CPPFLAGS=$CPPFLAGS +CPPFLAGS="-Ig2-0.70/src/ -Lg2-0.70/ ${CPPFLAGS}" + + + + +echo "$as_me:$LINENO: checking for gdImageLine in -lgd" >&5 +echo $ECHO_N "checking for gdImageLine in -lgd... $ECHO_C" >&6 +if test "${ac_cv_lib_gd_gdImageLine+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lgd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gdImageLine (); +int +main () +{ +gdImageLine (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_gd_gdImageLine=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_gd_gdImageLine=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_gd_gdImageLine" >&5 +echo "${ECHO_T}$ac_cv_lib_gd_gdImageLine" >&6 +if test $ac_cv_lib_gd_gdImageLine = yes; then + cat >>confdefs.h <<_ACEOF +#define HAVE_LIBGD 1 +_ACEOF + + LIBS="-lgd $LIBS" + +fi + + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu +echo "$as_me:$LINENO: checking how to run the C++ preprocessor" >&5 +echo $ECHO_N "checking how to run the C++ preprocessor... $ECHO_C" >&6 +if test -z "$CXXCPP"; then + if test "${ac_cv_prog_CXXCPP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # Double quotes because CXXCPP needs to be expanded + for CXXCPP in "$CXX -E" "/lib/cpp" + do + ac_preproc_ok=false +for ac_cxx_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_cxx_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_cxx_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_cxx_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_cxx_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + break +fi + + done + ac_cv_prog_CXXCPP=$CXXCPP + +fi + CXXCPP=$ac_cv_prog_CXXCPP +else + ac_cv_prog_CXXCPP=$CXXCPP +fi +echo "$as_me:$LINENO: result: $CXXCPP" >&5 +echo "${ECHO_T}$CXXCPP" >&6 +ac_preproc_ok=false +for ac_cxx_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_cxx_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_cxx_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_cxx_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_cxx_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + : +else + { { echo "$as_me:$LINENO: error: C++ preprocessor \"$CXXCPP\" fails sanity check +See \`config.log' for more details." >&5 +echo "$as_me: error: C++ preprocessor \"$CXXCPP\" fails sanity check +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu + + +echo "$as_me:$LINENO: checking for egrep" >&5 +echo $ECHO_N "checking for egrep... $ECHO_C" >&6 +if test "${ac_cv_prog_egrep+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if echo a | (grep -E '(a|b)') >/dev/null 2>&1 + then ac_cv_prog_egrep='grep -E' + else ac_cv_prog_egrep='egrep' + fi +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5 +echo "${ECHO_T}$ac_cv_prog_egrep" >&6 + EGREP=$ac_cv_prog_egrep + + +echo "$as_me:$LINENO: checking for ANSI C header files" >&5 +echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6 +if test "${ac_cv_header_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_header_stdc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_header_stdc=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + +if test $ac_cv_header_stdc = yes; then + # SunOS 4.x string.h does not declare mem*, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "memchr" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "free" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi. + if test "$cross_compiling" = yes; then + : +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#if ((' ' & 0x0FF) == 0x020) +# define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +#else +# define ISLOWER(c) \ + (('a' <= (c) && (c) <= 'i') \ + || ('j' <= (c) && (c) <= 'r') \ + || ('s' <= (c) && (c) <= 'z')) +# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +#endif + +#define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +int +main () +{ + int i; + for (i = 0; i < 256; i++) + if (XOR (islower (i), ISLOWER (i)) + || toupper (i) != TOUPPER (i)) + exit(2); + exit (0); +} +_ACEOF +rm -f conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && { ac_try='./conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: program exited with status $ac_status" >&5 +echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +( exit $ac_status ) +ac_cv_header_stdc=no +fi +rm -f core *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext +fi +fi +fi +echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5 +echo "${ECHO_T}$ac_cv_header_stdc" >&6 +if test $ac_cv_header_stdc = yes; then + +cat >>confdefs.h <<\_ACEOF +#define STDC_HEADERS 1 +_ACEOF + +fi + +# On IRIX 5.3, sys/types and inttypes.h are conflicting. + + + + + + + + + +for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default + +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_Header=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_Header=no" +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + +if test "${ac_cv_header_g2_h+set}" = set; then + echo "$as_me:$LINENO: checking for g2.h" >&5 +echo $ECHO_N "checking for g2.h... $ECHO_C" >&6 +if test "${ac_cv_header_g2_h+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +fi +echo "$as_me:$LINENO: result: $ac_cv_header_g2_h" >&5 +echo "${ECHO_T}$ac_cv_header_g2_h" >&6 +else + # Is the header compilable? +echo "$as_me:$LINENO: checking g2.h usability" >&5 +echo $ECHO_N "checking g2.h usability... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +#include +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_header_compiler=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_header_compiler=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_compiler" >&5 +echo "${ECHO_T}$ac_header_compiler" >&6 + +# Is the header present? +echo "$as_me:$LINENO: checking g2.h presence" >&5 +echo $ECHO_N "checking g2.h presence... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_cxx_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_cxx_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + ac_header_preproc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + ac_header_preproc=no +fi +rm -f conftest.err conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_preproc" >&5 +echo "${ECHO_T}$ac_header_preproc" >&6 + +# So? What about this header? +case $ac_header_compiler:$ac_header_preproc:$ac_cxx_preproc_warn_flag in + yes:no: ) + { echo "$as_me:$LINENO: WARNING: g2.h: accepted by the compiler, rejected by the preprocessor!" >&5 +echo "$as_me: WARNING: g2.h: accepted by the compiler, rejected by the preprocessor!" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: proceeding with the compiler's result" >&5 +echo "$as_me: WARNING: g2.h: proceeding with the compiler's result" >&2;} + ac_header_preproc=yes + ;; + no:yes:* ) + { echo "$as_me:$LINENO: WARNING: g2.h: present but cannot be compiled" >&5 +echo "$as_me: WARNING: g2.h: present but cannot be compiled" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: check for missing prerequisite headers?" >&5 +echo "$as_me: WARNING: g2.h: check for missing prerequisite headers?" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: see the Autoconf documentation" >&5 +echo "$as_me: WARNING: g2.h: see the Autoconf documentation" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: section \"Present But Cannot Be Compiled\"" >&5 +echo "$as_me: WARNING: g2.h: section \"Present But Cannot Be Compiled\"" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: proceeding with the preprocessor's result" >&5 +echo "$as_me: WARNING: g2.h: proceeding with the preprocessor's result" >&2;} + { echo "$as_me:$LINENO: WARNING: g2.h: in the future, the compiler will take precedence" >&5 +echo "$as_me: WARNING: g2.h: in the future, the compiler will take precedence" >&2;} + ( + cat <<\_ASBOX +## ------------------------------------------------ ## +## Report this to mhoechsm@techfak.uni-bielefeld.de ## +## ------------------------------------------------ ## +_ASBOX + ) | + sed "s/^/$as_me: WARNING: /" >&2 + ;; +esac +echo "$as_me:$LINENO: checking for g2.h" >&5 +echo $ECHO_N "checking for g2.h... $ECHO_C" >&6 +if test "${ac_cv_header_g2_h+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_header_g2_h=$ac_header_preproc +fi +echo "$as_me:$LINENO: result: $ac_cv_header_g2_h" >&5 +echo "${ECHO_T}$ac_cv_header_g2_h" >&6 + +fi +if test $ac_cv_header_g2_h = yes; then + +cat >>confdefs.h <<\_ACEOF +#define HAVE_LIBG2 1 +_ACEOF + +else + { echo "$as_me:$LINENO: WARNING: Compiling without support for graphical output. Install the g2 library that comes with the RNAforester distribution or download the latest version at http://g2.sourceforge.net/" >&5 +echo "$as_me: WARNING: Compiling without support for graphical output. Install the g2 library that comes with the RNAforester distribution or download the latest version at http://g2.sourceforge.net/" >&2;} +fi + + + +echo "$as_me:$LINENO: checking for an ANSI C-conforming const" >&5 +echo $ECHO_N "checking for an ANSI C-conforming const... $ECHO_C" >&6 +if test "${ac_cv_c_const+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +/* FIXME: Include the comments suggested by Paul. */ +#ifndef __cplusplus + /* Ultrix mips cc rejects this. */ + typedef int charset[2]; + const charset x; + /* SunOS 4.1.1 cc rejects this. */ + char const *const *ccp; + char **p; + /* NEC SVR4.0.2 mips cc rejects this. */ + struct point {int x, y;}; + static struct point const zero = {0,0}; + /* AIX XL C 1.02.0.0 rejects this. + It does not let you subtract one const X* pointer from another in + an arm of an if-expression whose if-part is not a constant + expression */ + const char *g = "string"; + ccp = &g + (g ? g-g : 0); + /* HPUX 7.0 cc rejects these. */ + ++ccp; + p = (char**) ccp; + ccp = (char const *const *) p; + { /* SCO 3.2v4 cc rejects this. */ + char *t; + char const *s = 0 ? (char *) 0 : (char const *) 0; + + *t++ = 0; + } + { /* Someone thinks the Sun supposedly-ANSI compiler will reject this. */ + int x[] = {25, 17}; + const int *foo = &x[0]; + ++foo; + } + { /* Sun SC1.0 ANSI compiler rejects this -- but not the above. */ + typedef const int *iptr; + iptr p = 0; + ++p; + } + { /* AIX XL C 1.02.0.0 rejects this saying + "k.c", line 2.27: 1506-025 (S) Operand must be a modifiable lvalue. */ + struct s { int j; const int *ap[3]; }; + struct s *b; b->j = 5; + } + { /* ULTRIX-32 V3.1 (Rev 9) vcc rejects this */ + const int foo = 10; + } +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_c_const=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_c_const=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_c_const" >&5 +echo "${ECHO_T}$ac_cv_c_const" >&6 +if test $ac_cv_c_const = no; then + +cat >>confdefs.h <<\_ACEOF +#define const +_ACEOF + +fi + +echo "$as_me:$LINENO: checking for inline" >&5 +echo $ECHO_N "checking for inline... $ECHO_C" >&6 +if test "${ac_cv_c_inline+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_c_inline=no +for ac_kw in inline __inline__ __inline; do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifndef __cplusplus +typedef int foo_t; +static $ac_kw foo_t static_foo () {return 0; } +$ac_kw foo_t foo () {return 0; } +#endif + +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_c_inline=$ac_kw; break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_inline" >&5 +echo "${ECHO_T}$ac_cv_c_inline" >&6 + + +case $ac_cv_c_inline in + inline | yes) ;; + *) + case $ac_cv_c_inline in + no) ac_val=;; + *) ac_val=$ac_cv_c_inline;; + esac + cat >>confdefs.h <<_ACEOF +#ifndef __cplusplus +#define inline $ac_val +#endif +_ACEOF + ;; +esac + +echo "$as_me:$LINENO: checking for size_t" >&5 +echo $ECHO_N "checking for size_t... $ECHO_C" >&6 +if test "${ac_cv_type_size_t+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +int +main () +{ +if ((size_t *) 0) + return 0; +if (sizeof (size_t)) + return 0; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? 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Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +_ACEOF + +# Files that config.status was made for. +if test -n "$ac_config_files"; then + echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_headers"; then + echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_links"; then + echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_commands"; then + echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS +fi + +cat >>$CONFIG_STATUS <<\_ACEOF + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF +ac_cs_version="\\ +RNAforester config.status 1.5 +configured by $0, generated by GNU Autoconf 2.59, + with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=$srcdir +INSTALL="$INSTALL" +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +# If no file are specified by the user, then we need to provide default +# value. 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Make it in the build tree +# simply because there is no reason to put it here, and in addition, +# creating and moving files from /tmp can sometimes cause problems. +# Create a temporary directory, and hook for its removal unless debugging. +$debug || +{ + trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0 + trap '{ (exit 1); exit 1; }' 1 2 13 15 +} + +# Create a (secure) tmp directory for tmp files. + +{ + tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` && + test -n "$tmp" && test -d "$tmp" +} || +{ + tmp=./confstat$$-$RANDOM + (umask 077 && mkdir $tmp) +} || +{ + echo "$me: cannot create a temporary directory in ." >&2 + { (exit 1); exit 1; } +} + +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF + +# +# CONFIG_FILES section. +# + +# No need to generate the scripts if there are no CONFIG_FILES. +# This happens for instance when ./config.status config.h +if test -n "\$CONFIG_FILES"; then + # Protect against being on the right side of a sed subst in config.status. + sed 's/,@/@@/; s/@,/@@/; s/,;t t\$/@;t t/; /@;t t\$/s/[\\\\&,]/\\\\&/g; + s/@@/,@/; s/@@/@,/; s/@;t t\$/,;t t/' >\$tmp/subs.sed <<\\CEOF +s,@SHELL@,$SHELL,;t t +s,@PATH_SEPARATOR@,$PATH_SEPARATOR,;t t +s,@PACKAGE_NAME@,$PACKAGE_NAME,;t t +s,@PACKAGE_TARNAME@,$PACKAGE_TARNAME,;t t +s,@PACKAGE_VERSION@,$PACKAGE_VERSION,;t t +s,@PACKAGE_STRING@,$PACKAGE_STRING,;t t +s,@PACKAGE_BUGREPORT@,$PACKAGE_BUGREPORT,;t t +s,@exec_prefix@,$exec_prefix,;t t +s,@prefix@,$prefix,;t t +s,@program_transform_name@,$program_transform_name,;t t +s,@bindir@,$bindir,;t t +s,@sbindir@,$sbindir,;t t +s,@libexecdir@,$libexecdir,;t t +s,@datadir@,$datadir,;t t +s,@sysconfdir@,$sysconfdir,;t t +s,@sharedstatedir@,$sharedstatedir,;t t +s,@localstatedir@,$localstatedir,;t t +s,@libdir@,$libdir,;t t +s,@includedir@,$includedir,;t t +s,@oldincludedir@,$oldincludedir,;t t +s,@infodir@,$infodir,;t t +s,@mandir@,$mandir,;t t +s,@build_alias@,$build_alias,;t t +s,@host_alias@,$host_alias,;t t +s,@target_alias@,$target_alias,;t t +s,@DEFS@,$DEFS,;t t +s,@ECHO_C@,$ECHO_C,;t t +s,@ECHO_N@,$ECHO_N,;t t +s,@ECHO_T@,$ECHO_T,;t t +s,@LIBS@,$LIBS,;t t +s,@INSTALL_PROGRAM@,$INSTALL_PROGRAM,;t t +s,@INSTALL_SCRIPT@,$INSTALL_SCRIPT,;t t +s,@INSTALL_DATA@,$INSTALL_DATA,;t t +s,@CYGPATH_W@,$CYGPATH_W,;t t +s,@PACKAGE@,$PACKAGE,;t t +s,@VERSION@,$VERSION,;t t +s,@ACLOCAL@,$ACLOCAL,;t t +s,@AUTOCONF@,$AUTOCONF,;t t +s,@AUTOMAKE@,$AUTOMAKE,;t t +s,@AUTOHEADER@,$AUTOHEADER,;t t +s,@MAKEINFO@,$MAKEINFO,;t t +s,@install_sh@,$install_sh,;t t +s,@STRIP@,$STRIP,;t t +s,@ac_ct_STRIP@,$ac_ct_STRIP,;t t +s,@INSTALL_STRIP_PROGRAM@,$INSTALL_STRIP_PROGRAM,;t t +s,@mkdir_p@,$mkdir_p,;t t +s,@AWK@,$AWK,;t t +s,@SET_MAKE@,$SET_MAKE,;t t +s,@am__leading_dot@,$am__leading_dot,;t t +s,@AMTAR@,$AMTAR,;t t +s,@am__tar@,$am__tar,;t t +s,@am__untar@,$am__untar,;t t +s,@CXX@,$CXX,;t t +s,@CXXFLAGS@,$CXXFLAGS,;t t +s,@LDFLAGS@,$LDFLAGS,;t t +s,@CPPFLAGS@,$CPPFLAGS,;t t +s,@ac_ct_CXX@,$ac_ct_CXX,;t t +s,@EXEEXT@,$EXEEXT,;t t +s,@OBJEXT@,$OBJEXT,;t t +s,@DEPDIR@,$DEPDIR,;t t +s,@am__include@,$am__include,;t t +s,@am__quote@,$am__quote,;t t +s,@AMDEP_TRUE@,$AMDEP_TRUE,;t t +s,@AMDEP_FALSE@,$AMDEP_FALSE,;t t +s,@AMDEPBACKSLASH@,$AMDEPBACKSLASH,;t t +s,@CXXDEPMODE@,$CXXDEPMODE,;t t +s,@am__fastdepCXX_TRUE@,$am__fastdepCXX_TRUE,;t t +s,@am__fastdepCXX_FALSE@,$am__fastdepCXX_FALSE,;t t +s,@CC@,$CC,;t t +s,@CFLAGS@,$CFLAGS,;t t +s,@ac_ct_CC@,$ac_ct_CC,;t t +s,@CCDEPMODE@,$CCDEPMODE,;t t +s,@am__fastdepCC_TRUE@,$am__fastdepCC_TRUE,;t t +s,@am__fastdepCC_FALSE@,$am__fastdepCC_FALSE,;t t +s,@CXXCPP@,$CXXCPP,;t t +s,@EGREP@,$EGREP,;t t +s,@subdirs@,$subdirs,;t t +s,@LIBOBJS@,$LIBOBJS,;t t +s,@LTLIBOBJS@,$LTLIBOBJS,;t t +CEOF + +_ACEOF + + cat >>$CONFIG_STATUS <<\_ACEOF + # Split the substitutions into bite-sized pieces for seds with + # small command number limits, like on Digital OSF/1 and HP-UX. + ac_max_sed_lines=48 + ac_sed_frag=1 # Number of current file. + ac_beg=1 # First line for current file. + ac_end=$ac_max_sed_lines # Line after last line for current file. + ac_more_lines=: + ac_sed_cmds= + while $ac_more_lines; do + if test $ac_beg -gt 1; then + sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + else + sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + fi + if test ! 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The first handles `#define' +# templates, and the second `#undef' templates. +# And first: Protect against being on the right side of a sed subst in +# config.status. Protect against being in an unquoted here document +# in config.status. +rm -f conftest.defines conftest.undefs +# Using a here document instead of a string reduces the quoting nightmare. +# Putting comments in sed scripts is not portable. +# +# `end' is used to avoid that the second main sed command (meant for +# 0-ary CPP macros) applies to n-ary macro definitions. +# See the Autoconf documentation for `clear'. +cat >confdef2sed.sed <<\_ACEOF +s/[\\&,]/\\&/g +s,[\\$`],\\&,g +t clear +: clear +s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*\)\(([^)]*)\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1\2${ac_dC}\3${ac_dD},gp +t end +s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1${ac_dC}\2${ac_dD},gp +: end +_ACEOF +# If some macros were called several times there might be several times +# the same #defines, which is useless. Nevertheless, we may not want to +# sort them, since we want the *last* AC-DEFINE to be honored. +uniq confdefs.h | sed -n -f confdef2sed.sed >conftest.defines +sed 's/ac_d/ac_u/g' conftest.defines >conftest.undefs +rm -f confdef2sed.sed + +# This sed command replaces #undef with comments. This is necessary, for +# example, in the case of _POSIX_SOURCE, which is predefined and required +# on some systems where configure will not decide to define it. +cat >>conftest.undefs <<\_ACEOF +s,^[ ]*#[ ]*undef[ ][ ]*[a-zA-Z_][a-zA-Z_0-9]*,/* & */, +_ACEOF + +# Break up conftest.defines because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #define templates only if necessary.' >>$CONFIG_STATUS +echo ' if grep "^[ ]*#[ ]*define" $tmp/in >/dev/null; then' >>$CONFIG_STATUS +echo ' # If there are no defines, we may have an empty if/fi' >>$CONFIG_STATUS +echo ' :' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.defines >/dev/null +do + # Write a limited-size here document to $tmp/defines.sed. + echo ' cat >$tmp/defines.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#define' lines. + echo '/^[ ]*#[ ]*define/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.defines >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/defines.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.defines >conftest.tail + rm -f conftest.defines + mv conftest.tail conftest.defines +done +rm -f conftest.defines +echo ' fi # grep' >>$CONFIG_STATUS +echo >>$CONFIG_STATUS + +# Break up conftest.undefs because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #undef templates' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.undefs >/dev/null +do + # Write a limited-size here document to $tmp/undefs.sed. + echo ' cat >$tmp/undefs.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#undef' + echo '/^[ ]*#[ ]*undef/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.undefs >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/undefs.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.undefs >conftest.tail + rm -f conftest.undefs + mv conftest.tail conftest.undefs +done +rm -f conftest.undefs + +cat >>$CONFIG_STATUS <<\_ACEOF + # Let's still pretend it is `configure' which instantiates (i.e., don't + # use $as_me), people would be surprised to read: + # /* config.h. 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We are building in place. + ac_srcdir=. + if test -z "$ac_top_builddir"; then + ac_top_srcdir=. + else + ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'` + fi ;; + [\\/]* | ?:[\\/]* ) # Absolute path. + ac_srcdir=$srcdir$ac_dir_suffix; + ac_top_srcdir=$srcdir ;; + *) # Relative path. + ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix + ac_top_srcdir=$ac_top_builddir$srcdir ;; +esac + +# Do not use `cd foo && pwd` to compute absolute paths, because +# the directories may not exist. +case `pwd` in +.) ac_abs_builddir="$ac_dir";; +*) + case "$ac_dir" in + .) ac_abs_builddir=`pwd`;; + [\\/]* | ?:[\\/]* ) ac_abs_builddir="$ac_dir";; + *) ac_abs_builddir=`pwd`/"$ac_dir";; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_builddir=${ac_top_builddir}.;; +*) + case ${ac_top_builddir}. in + .) ac_abs_top_builddir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_builddir=${ac_top_builddir}.;; + *) ac_abs_top_builddir=$ac_abs_builddir/${ac_top_builddir}.;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_srcdir=$ac_srcdir;; +*) + case $ac_srcdir in + .) ac_abs_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_srcdir=$ac_srcdir;; + *) ac_abs_srcdir=$ac_abs_builddir/$ac_srcdir;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_srcdir=$ac_top_srcdir;; +*) + case $ac_top_srcdir in + .) ac_abs_top_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_srcdir=$ac_top_srcdir;; + *) ac_abs_top_srcdir=$ac_abs_builddir/$ac_top_srcdir;; + esac;; +esac + + + cd $ac_dir + + # Check for guested configure; otherwise get Cygnus style configure. + if test -f $ac_srcdir/configure.gnu; then + ac_sub_configure="$SHELL '$ac_srcdir/configure.gnu'" + elif test -f $ac_srcdir/configure; then + ac_sub_configure="$SHELL '$ac_srcdir/configure'" + elif test -f $ac_srcdir/configure.in; then + ac_sub_configure=$ac_configure + else + { echo "$as_me:$LINENO: WARNING: no configuration information is in $ac_dir" >&5 +echo "$as_me: WARNING: no configuration information is in $ac_dir" >&2;} + ac_sub_configure= + fi + + # The recursion is here. + if test -n "$ac_sub_configure"; then + # Make the cache file name correct relative to the subdirectory. + case $cache_file in + [\\/]* | ?:[\\/]* ) ac_sub_cache_file=$cache_file ;; + *) # Relative path. + ac_sub_cache_file=$ac_top_builddir$cache_file ;; + esac + + { echo "$as_me:$LINENO: running $ac_sub_configure $ac_sub_configure_args --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir" >&5 +echo "$as_me: running $ac_sub_configure $ac_sub_configure_args --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir" >&6;} + # The eval makes quoting arguments work. + eval $ac_sub_configure $ac_sub_configure_args \ + --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir || + { { echo "$as_me:$LINENO: error: $ac_sub_configure failed for $ac_dir" >&5 +echo "$as_me: error: $ac_sub_configure failed for $ac_dir" >&2;} + { (exit 1); exit 1; }; } + fi + + cd $ac_popdir + done +fi + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/configure.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/configure.in new file mode 100755 index 00000000..b36bdfc0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/configure.in @@ -0,0 +1,64 @@ +dnl Process this file with autoconf to produce a configure script. +AC_REVISION($Revision: 1.13 $) +AC_INIT(RNAforester,1.5,mhoechsm@techfak.uni-bielefeld.de,RNAforester) +AC_PREREQ(2.53) +AM_INIT_AUTOMAKE + +dnl create a config.h file (Automake will add -DHAVE_CONFIG_H) +AM_CONFIG_HEADER(config.h) + +dnl Checks for programs. +AC_PROG_CXX +AC_PROG_CC +AC_LANG(C++) + +dnl Checks for libraries. +dnl AC_CHECK_LIB(g2,g2_open_vd,,AC_MSG_WARN(Compiling without support for graphical output. Install the g2 library that comes with the RNAforester distribution or download the latest version at http://g2.sourceforge.net/)) + +AC_ARG_WITH(ViennaRNA-lib, + [--with-ViennaRNA-lib where to search for libRNA.a], + LIBS=["$withval/libRNA.a ${LIBS}"] && AC_DEFINE(HAVE_LIBRNA,1,Define to 1 if you have the `RNA' library (-lRNA).), + LDFLAGS="-L../../lib ${LDFLAGS}" + if test -r "../lib/fold.c"; then + AC_DEFINE(HAVE_LIBRNA) + LIBS=["-lRNA ${LIBS}"] + AC_MSG_RESULT([using (to be built) libRNA.a in ../lib]) + fi + ) +dnl AC_CHECK_LIB(RNA, fold,,AC_MSG_WARN(Vienna RNA library libRNA.a was not found. RNAforester will be compiled without the structure prediction option -p and graphical output)) + +save_CPPFLAGS=$CPPFLAGS +CPPFLAGS=["-Ig2-0.70/src/ -Lg2-0.70/ ${CPPFLAGS}"] + + +AC_CHECK_LIB(gd,gdImageLine,,) + +dnl Checks for header files. +AC_HEADER_STDC +AC_CHECK_HEADER(g2.h,AC_DEFINE(HAVE_LIBG2,1,Define to 1 if you have the `g2' library (-lg2).),AC_MSG_WARN(Compiling without support for graphical output. Install the g2 library that comes with the RNAforester distribution or download the latest version at http://g2.sourceforge.net/)) +dnl AC_CHECK_HEADER(g2_PS.h,,AC_MSG_WARN(Compiling without support for graphical output. Install the g2 library that comes with the RNAforester distribution or download the latest version at http://g2.sourceforge.net/)) + +dnl Checks for typedefs, structures, and compiler characteristics. +AC_C_CONST +AC_C_INLINE +AC_TYPE_SIZE_T + +CPPFLAGS="$save_CPPFLAGS -I../g2-0.70/include/" +LDFLAGS=["-L../g2-0.70 ${LDFLAGS}"] + +if ${HAVE_LIBG2}; then + LIBS=["-lg2 ${LIBS}"] +fi + +AC_SUBST(CXX) +AC_SUBST(CPPFLAGS) +AC_SUBST(LIBS) +AC_SUBST(LDFLAGS) + +dnl Checks for library functions. + +AC_CONFIG_SUBDIRS(g2-0.70) +AC_OUTPUT(Makefile src/Makefile man/Makefile) + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/depcomp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/depcomp new file mode 100755 index 00000000..807b991f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/depcomp @@ -0,0 +1,423 @@ +#! /bin/sh + +# depcomp - compile a program generating dependencies as side-effects +# Copyright 1999, 2000 Free Software Foundation, Inc. + +# This program is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2, or (at your option) +# any later version. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the +# GNU General Public License for more details. + +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA +# 02111-1307, USA. + +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Originally written by Alexandre Oliva . + +if test -z "$depmode" || test -z "$source" || test -z "$object"; then + echo "depcomp: Variables source, object and depmode must be set" 1>&2 + exit 1 +fi +# `libtool' can also be set to `yes' or `no'. + +if test -z "$depfile"; then + base=`echo "$object" | sed -e 's,^.*/,,' -e 's,\.\([^.]*\)$,.P\1,'` + dir=`echo "$object" | sed 's,/.*$,/,'` + if test "$dir" = "$object"; then + dir= + fi + # FIXME: should be _deps on DOS. + depfile="$dir.deps/$base" +fi + +tmpdepfile=${tmpdepfile-`echo "$depfile" | sed 's/\.\([^.]*\)$/.T\1/'`} + +rm -f "$tmpdepfile" + +# Some modes work just like other modes, but use different flags. We +# parameterize here, but still list the modes in the big case below, +# to make depend.m4 easier to write. Note that we *cannot* use a case +# here, because this file can only contain one case statement. +if test "$depmode" = hp; then + # HP compiler uses -M and no extra arg. + gccflag=-M + depmode=gcc +fi + +if test "$depmode" = dashXmstdout; then + # This is just like dashmstdout with a different argument. + dashmflag=-xM + depmode=dashmstdout +fi + +case "$depmode" in +gcc3) +## gcc 3 implements dependency tracking that does exactly what +## we want. Yay! Note: for some reason libtool 1.4 doesn't like +## it if -MD -MP comes after the -MF stuff. Hmm. + "$@" -MT "$object" -MD -MP -MF "$tmpdepfile" + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + mv "$tmpdepfile" "$depfile" + ;; + +gcc) +## There are various ways to get dependency output from gcc. Here's +## why we pick this rather obscure method: +## - Don't want to use -MD because we'd like the dependencies to end +## up in a subdir. Having to rename by hand is ugly. +## (We might end up doing this anyway to support other compilers.) +## - The DEPENDENCIES_OUTPUT environment variable makes gcc act like +## -MM, not -M (despite what the docs say). +## - Using -M directly means running the compiler twice (even worse +## than renaming). + if test -z "$gccflag"; then + gccflag=-MD, + fi + "$@" -Wp,"$gccflag$tmpdepfile" + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + rm -f "$depfile" + echo "$object : \\" > "$depfile" + alpha=ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz +## The second -e expression handles DOS-style file names with drive letters. + sed -e 's/^[^:]*: / /' \ + -e 's/^['$alpha']:\/[^:]*: / /' < "$tmpdepfile" >> "$depfile" +## This next piece of magic avoids the `deleted header file' problem. +## The problem is that when a header file which appears in a .P file +## is deleted, the dependency causes make to die (because there is +## typically no way to rebuild the header). We avoid this by adding +## dummy dependencies for each header file. Too bad gcc doesn't do +## this for us directly. + tr ' ' ' +' < "$tmpdepfile" | +## Some versions of gcc put a space before the `:'. On the theory +## that the space means something, we add a space to the output as +## well. +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +hp) + # This case exists only to let depend.m4 do its work. It works by + # looking at the text of this script. This case will never be run, + # since it is checked for above. + exit 1 + ;; + +sgi) + if test "$libtool" = yes; then + "$@" "-Wp,-MDupdate,$tmpdepfile" + else + "$@" -MDupdate "$tmpdepfile" + fi + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + rm -f "$depfile" + + if test -f "$tmpdepfile"; then # yes, the sourcefile depend on other files + echo "$object : \\" > "$depfile" + + # Clip off the initial element (the dependent). Don't try to be + # clever and replace this with sed code, as IRIX sed won't handle + # lines with more than a fixed number of characters (4096 in + # IRIX 6.2 sed, 8192 in IRIX 6.5). We also remove comment lines; + # the IRIX cc adds comments like `#:fec' to the end of the + # dependency line. + tr ' ' ' +' < "$tmpdepfile" \ + | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' | \ + tr ' +' ' ' >> $depfile + echo >> $depfile + + # The second pass generates a dummy entry for each header file. + tr ' ' ' +' < "$tmpdepfile" \ + | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' -e 's/$/:/' \ + >> $depfile + else + # The sourcefile does not contain any dependencies, so just + # store a dummy comment line, to avoid errors with the Makefile + # "include basename.Plo" scheme. + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +aix) + # The C for AIX Compiler uses -M and outputs the dependencies + # in a .u file. This file always lives in the current directory. + # Also, the AIX compiler puts `$object:' at the start of each line; + # $object doesn't have directory information. + stripped=`echo "$object" | sed -e 's,^.*/,,' -e 's/\(.*\)\..*$/\1/'` + tmpdepfile="$stripped.u" + outname="$stripped.o" + if test "$libtool" = yes; then + "$@" -Wc,-M + else + "$@" -M + fi + + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + + if test -f "$tmpdepfile"; then + # Each line is of the form `foo.o: dependent.h'. + # Do two passes, one to just change these to + # `$object: dependent.h' and one to simply `dependent.h:'. + sed -e "s,^$outname:,$object :," < "$tmpdepfile" > "$depfile" + sed -e "s,^$outname: \(.*\)$,\1:," < "$tmpdepfile" >> "$depfile" + else + # The sourcefile does not contain any dependencies, so just + # store a dummy comment line, to avoid errors with the Makefile + # "include basename.Plo" scheme. + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +tru64) + # The Tru64 compiler uses -MD to generate dependencies as a side + # effect. `cc -MD -o foo.o ...' puts the dependencies into `foo.o.d'. + # At least on Alpha/Redhat 6.1, Compaq CCC V6.2-504 seems to put + # dependencies in `foo.d' instead, so we check for that too. + # Subdirectories are respected. + dir=`echo "$object" | sed -e 's|/[^/]*$|/|'` + test "x$dir" = "x$object" && dir= + base=`echo "$object" | sed -e 's|^.*/||' -e 's/\.o$//' -e 's/\.lo$//'` + + if test "$libtool" = yes; then + tmpdepfile1="$dir.libs/$base.lo.d" + tmpdepfile2="$dir.libs/$base.d" + "$@" -Wc,-MD + else + tmpdepfile1="$dir$base.o.d" + tmpdepfile2="$dir$base.d" + "$@" -MD + fi + + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile1" "$tmpdepfile2" + exit $stat + fi + + if test -f "$tmpdepfile1"; then + tmpdepfile="$tmpdepfile1" + else + tmpdepfile="$tmpdepfile2" + fi + if test -f "$tmpdepfile"; then + sed -e "s,^.*\.[a-z]*:,$object:," < "$tmpdepfile" > "$depfile" + # That's a space and a tab in the []. + sed -e 's,^.*\.[a-z]*:[ ]*,,' -e 's,$,:,' < "$tmpdepfile" >> "$depfile" + else + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +#nosideeffect) + # This comment above is used by automake to tell side-effect + # dependency tracking mechanisms from slower ones. + +dashmstdout) + # Important note: in order to support this mode, a compiler *must* + # always write the proprocessed file to stdout, regardless of -o. + "$@" || exit $? + + # Remove the call to Libtool. + if test "$libtool" = yes; then + while test $1 != '--mode=compile'; do + shift + done + shift + fi + + # Remove `-o $object'. We will use -o /dev/null later, + # however we can't do the remplacement now because + # `-o $object' might simply not be used + IFS=" " + for arg + do + case $arg in + -o) + shift + ;; + $object) + shift + ;; + *) + set fnord "$@" "$arg" + shift # fnord + shift # $arg + ;; + esac + done + + test -z "$dashmflag" && dashmflag=-M + "$@" -o /dev/null $dashmflag | sed 's:^[^:]*\:[ ]*:'"$object"'\: :' > "$tmpdepfile" + rm -f "$depfile" + cat < "$tmpdepfile" > "$depfile" + tr ' ' ' +' < "$tmpdepfile" | \ +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +dashXmstdout) + # This case only exists to satisfy depend.m4. It is never actually + # run, as this mode is specially recognized in the preamble. + exit 1 + ;; + +makedepend) + "$@" || exit $? + # X makedepend + shift + cleared=no + for arg in "$@"; do + case $cleared in + no) + set ""; shift + cleared=yes ;; + esac + case "$arg" in + -D*|-I*) + set fnord "$@" "$arg"; shift ;; + -*) + ;; + *) + set fnord "$@" "$arg"; shift ;; + esac + done + obj_suffix="`echo $object | sed 's/^.*\././'`" + touch "$tmpdepfile" + ${MAKEDEPEND-makedepend} -o"$obj_suffix" -f"$tmpdepfile" "$@" + rm -f "$depfile" + cat < "$tmpdepfile" > "$depfile" + sed '1,2d' "$tmpdepfile" | tr ' ' ' +' | \ +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" "$tmpdepfile".bak + ;; + +cpp) + # Important note: in order to support this mode, a compiler *must* + # always write the proprocessed file to stdout. + "$@" || exit $? + + # Remove the call to Libtool. + if test "$libtool" = yes; then + while test $1 != '--mode=compile'; do + shift + done + shift + fi + + # Remove `-o $object'. + IFS=" " + for arg + do + case $arg in + -o) + shift + ;; + $object) + shift + ;; + *) + set fnord "$@" "$arg" + shift # fnord + shift # $arg + ;; + esac + done + + "$@" -E | + sed -n '/^# [0-9][0-9]* "\([^"]*\)".*/ s:: \1 \\:p' | + sed '$ s: \\$::' > "$tmpdepfile" + rm -f "$depfile" + echo "$object : \\" > "$depfile" + cat < "$tmpdepfile" >> "$depfile" + sed < "$tmpdepfile" '/^$/d;s/^ //;s/ \\$//;s/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +msvisualcpp) + # Important note: in order to support this mode, a compiler *must* + # always write the proprocessed file to stdout, regardless of -o, + # because we must use -o when running libtool. + "$@" || exit $? + IFS=" " + for arg + do + case "$arg" in + "-Gm"|"/Gm"|"-Gi"|"/Gi"|"-ZI"|"/ZI") + set fnord "$@" + shift + shift + ;; + *) + set fnord "$@" "$arg" + shift + shift + ;; + esac + done + "$@" -E | + sed -n '/^#line [0-9][0-9]* "\([^"]*\)"/ s::echo "`cygpath -u \\"\1\\"`":p' | sort | uniq > "$tmpdepfile" + rm -f "$depfile" + echo "$object : \\" > "$depfile" + . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s:: \1 \\:p' >> "$depfile" + echo " " >> "$depfile" + . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s::\1\::p' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +none) + exec "$@" + ;; + +*) + echo "Unknown depmode $depmode" 1>&2 + exit 1 + ;; +esac + +exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CHANGES b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CHANGES new file mode 100755 index 00000000..37ec9157 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CHANGES @@ -0,0 +1,144 @@ +0.70 +==== +- added support for access to the physical devices low level handles +- added animation demo for Win32 +- improved cygwin compatibility +- improved spline implementation +- improved pixel compatibility between X11 and GD +- fixed X11 window position problem occured with some window managers +- fixed arc and filled arc functions +- fixed memory bug (thanks to Kurihara Satoshi) +- fixed problem with black bar if resource DLL was not compiled +- fixed problem with flickering and background behind text +- bug fix for background color in g2_win32_SetBackground + +0.62 +==== +- PS in place of X11 for demo_cpp + +0.61 +==== +- ANSI C streamlining + +0.60 +==== +- added FIG device +- added win32 mouse support +- added check for dashed lines to g2_test +- bugfixes + +0.51 +==== +- g2_perl improvements (added GD device, added splines, removed GIF, + retested, added simple README) +- added configurable logging +- added some new configuration parameters and slightly changed + configuration naming convention (g2_config.h) +- added doxygen comments for automatic docu generation +- general documentation update + +0.50 +==== +- removed GIF code +- improved fortran port + +0.49a +===== +- number of small fixes +- number of changes :) + +0.42 +==== +-license change to LGPL + +0.41b +===== +-added new Tijs Michels spline implementation +-small fixes in spline package +-added g2_spline_demo.c +-changed LINKDLL into G2L in g2.h +-removed some non ansi parts (e.g. // comments) +-added query pointer for X11 (mouse) + +0.41a +===== +-modified header files for usage with c++ +-modified header files for building Win32 DLL +-added DLL version to Win32 workspace +-added Tijs Michels spline implementation +-small fixes in Makefile.in + +0.40 +==== +- added perl support +- g2_draw_string replaced with g2_string +- added g2_image function +- added g2_control_pd.* files +- g2_device_exist moved to user space (perl) +- added g2_set_line_width support in GIF device +- added prefix to Makefile.in +- updated descrip.mms + +0.30 (23.10.1998) +================ +- finished Win32 implementation +- fixed bug in virtual device section +- minor changes in g2_X11.c (include string.h) +- finished VMS port (descrip.mms files) + +0.23 (09.07.1998) +================= +- finished Fortran interface (tested on Linux and DU) +- added arc and filled_arc emulation +- minor bug fix in g2_ui_control.c (thanks to E.M. (Mark) Palandri) +- finished GIF interface +- added new demo files +- some bug fixes + +0.22 (03.06.1998) +================= +- bugfix in g2_device.c +- minor changes + +0.21 (03.06.1998) +================= +- added g2_ld (last device) concept +- minor changes in make procedures +- back to the normal 'numbering' :-) +- added (very simple) demo0.c + +0.20a (02.06.1998) +================== +- added configure script +- changed file/make structure of g2 project +- changed version numbering (a-alpha, b-beta etc.) + +0.11 (30.04.1998) +================= +- fixed bug in Makefile +- fixed bug with r rescaling (circle, ellipse and arc) in g2_graphic_pd.c +- small fix in g2_X11 +- added g2_us2pds_xxxx in g2_util.c +- minor changes in makefile.i386 and makefile.alpha + +0.10 (24.04.1998) +================= +- major kernel rewrite +- small fixes in X11 part +- removed funix: g2_AllocateBasicColors +- added Fortran interface (alpha) + +0.02 (31.03.1998) +================= +- new funix: g2_Save +- added contrib directory + + +0.01 (19.03.1998) +================= +- created CHANGES file :-) +- some small fixes +- added g2_attach_X11X and changed g2_attach_X11 to be a wrapper to + the new function +- added PostScript interface + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/COPYING b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/COPYING new file mode 100755 index 00000000..b1e3f5a2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/COPYING @@ -0,0 +1,504 @@ + GNU LESSER GENERAL PUBLIC LICENSE + Version 2.1, February 1999 + + Copyright (C) 1991, 1999 Free Software Foundation, Inc. + 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA + Everyone is permitted to copy and distribute verbatim copies + of this license document, but changing it is not allowed. + +[This is the first released version of the Lesser GPL. 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Here is a sample; alter the names: + + Yoyodyne, Inc., hereby disclaims all copyright interest in the + library `Frob' (a library for tweaking knobs) written by James Random Hacker. + + , 1 April 1990 + Ty Coon, President of Vice + +That's all there is to it! + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Repository new file mode 100755 index 00000000..317b1d1f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Entries new file mode 100755 index 00000000..d954ef27 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Entries @@ -0,0 +1,29 @@ +D/autom4te.cache//// +D/CVS//// +D/demo//// +D/doc//// +D/g2_perl//// +D/include//// +D/perl//// +D/src//// +/CHANGES/1.1/Tue Jun 14 21:02:57 2005// +/COPYING/1.1/Tue Apr 17 20:16:38 2001// +/INSTALL/1.1/Mon Mar 29 21:47:11 2004// +/Makefile.in/1.1/Thu Aug 4 12:40:53 2005// +/README/1.1/Sun Feb 29 23:47:46 2004// +/TODO/1.1/Sun Feb 29 23:47:46 2004// +/config.guess/1.1/Mon Jan 18 10:56:51 1999// +/config.sub/1.1/Mon Jan 18 10:56:51 1999// +/configure/1.1/Thu Aug 4 12:41:58 2005// +/configure.in/1.1/Wed Apr 21 03:19:15 2004// +/descrip.mms/1.1/Thu Nov 22 00:14:25 2001// +/g2.dsp/1.1/Sat Apr 17 21:21:11 2004// +/g2.dsw/1.1/Sat Apr 17 21:28:13 2004// +/g2_anim.dsp/1.1/Sat Apr 17 21:16:41 2004// +/g2demo.dsp/1.1/Sat Apr 17 21:21:11 2004// +/g2dll.dsp/1.1/Sat Apr 17 21:28:13 2004// +/g2res.dsp/1.1/Sat Apr 17 21:21:11 2004// +/gd.dsp/1.1/Sun Jun 6 12:50:15 1999// +/install-sh/1.1/Mon Jan 18 10:56:51 1999// +/simple_win32.dsp/1.1/Sat Apr 17 21:28:13 2004// +/Makefile/1.1/Fri Aug 5 10:17:46 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Repository new file mode 100755 index 00000000..0652b408 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/INSTALL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/INSTALL new file mode 100755 index 00000000..4fc58ad2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/INSTALL @@ -0,0 +1,94 @@ +Installation +============ + +LINUX +----- + +Either install RPM packet with binaries, or compile as described in the +UNIX section + +UNIX +---- + +1. Extract package with gzip -dc g2-xxxx.tar.gz | tar xvf - + +2. Run './configure' + +3. Run 'make depend' + +4. Optionally edit src/g2_config.h to fine-tune g2 behavior (only if + you know what are you doing) + +5. Run 'make' + +6. Run 'make install' or copy libg2.a and g2.h, g2_X11.h, g2_gd.h, and + g2_PS.h to the default locations for library and include files. + +7. cd to demo directory and run 'make demo' to compile demo + applications + +8. To rebuild documentation run 'make doc' (html, PS and pdf manual + should be already included into documentation). + + +WINDOWS NT +---------- + +1. Extract package: unzip 'g2-xxxx.zip' + +2. For gd support, please download the binary gd version and place it in a + folder next to g2 using default folder name gdwin32, i.e. it is expected + in ../gdwin32 from the folder this file is residing. + You also will need to create the bgd.lib file using makemsvcimport.bat + +3. MS Visual C++ users can build both library and demos with the supplied + project file: g2.xxx + users of gcc or other commandline based compilers with make support + continue as in Unix example + + +VMS +--- + +Note: VMS is not tested in latest builds. However descrip.mms is a +good starting point. + +1. set default to root of distribution directory + +2. type mms to build g2.olb library + +3. to compile demo files, set defualt to [.demo] and type mms + +4. to install: copy g2.olb and g2.h, g2_X11.h and g2_PS.h to install + directories + + +PNG-SUPPORT +----------- + +g2 needs to be linked to the free available gd library written by +Thomas Boutell in order to create PNG files. g2 is tested with +version 2.0.22 of gd. gd is available at http://www.boutell.com/gd/ and +at numerous mirror sites. Use a ftp search +(e.g. http://ftpsearch.ntnu.no/) and search for "gd1.3.tar.gz" to find +your nearest mirror site. + + +PERL SUPPORT +------------ +1. build g2 library +2. cd to g2_perl and run + perl Makefile.PL + make + make test + + +SHARED LIBRARIES +---------------- +Support for shared libraries is tested on Linux and OSF +(DigitalUnix). To build shared libraries type 'make shared'. If you +want to run demo applications without installed shared libraries, you +should add to LD_LIBRARY_PATH the path to the g2 shared library +(e.g. 'export LD_LIBRARY_PATH=$LD_LIBRARY_PATH:/some/path/to/g2') + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile new file mode 100755 index 00000000..93b66162 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile @@ -0,0 +1,149 @@ +# +# +# Makefile for g2 library +# +# + +G2_VERSION = 0.70 + +# +# g2 installation directories +# +LIBDIR = /usr/local/lib +INCDIR = /usr/local/include + + +#LIBDIR = $(HOME)/local/lib +#INCDIR = $(HOME)/local/include + +# +#------------------------ do not edit ------------------------ +# +SHELL = /bin/sh + +CC = gcc +CFLAGS = -I./src -g -O2 -I/usr/X11R6/include -I/usr/local/include -DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 +INSTALL = /usr/bin/install -c +INSTALL_DATA = ${INSTALL} -m 644 +FIND = find +MAKEDEPEND = makedepend +AR = ar +ARFLAGS = -cr +RANLIB = ranlib +LD = ld +LDFLAGS = -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd + + +BASE_DIR = ./src +BASE_SRC = $(BASE_DIR)/g2_device.c $(BASE_DIR)/g2_ui_control.c \ + $(BASE_DIR)/g2_util.c $(BASE_DIR)/g2_fif.c \ + $(BASE_DIR)/g2_virtual_device.c $(BASE_DIR)/g2_physical_device.c \ + $(BASE_DIR)/g2_graphic_pd.c $(BASE_DIR)/g2_control_pd.c \ + $(BASE_DIR)/g2_ui_graphic.c $(BASE_DIR)/g2_ui_virtual_device.c \ + $(BASE_DIR)/g2_ui_device.c $(BASE_DIR)/g2_splines.c +BASE_INS = $(BASE_DIR)/g2.h + + +PS_DIR = ./src/PS +PS_SRC = $(PS_DIR)/g2_PS.c +PS_INS = $(PS_DIR)/g2_PS.h + +FIG_DIR = ./src/FIG +FIG_SRC = $(FIG_DIR)/g2_FIG.c +FIG_INS = $(FIG_DIR)/g2_FIG.h + +X11_DIR = ./src/X11 +X11_SRC = $(X11_DIR)/g2_X11.c +X11_INS = $(X11_DIR)/g2_X11.h + +#WIN32_DIR = ./src/WIN32 +#WIN32_SRC = $(WIN32_DIR)/g2_win32.c $(WIN32_DIR)/g2_win32_thread.c +#WIN32_INS = $(WIN32_DIR)/g2_win32.h + +GD_DIR = ./src/GD +GD_SRC = $(GD_DIR)/g2_gd.c +GD_INS = $(GD_DIR)/g2_gd.h + + +SRC = $(BASE_SRC) $(PS_SRC) $(FIG_SRC) $(X11_SRC) $(WIN32_SRC) $(GD_SRC) +OBJ = $(SRC:.c=.o) + +INS = $(BASE_INS) $(PS_INS) $(FIG_INS) $(X11_INS) $(WIN32_INS) $(GD_INS) + +# +# define some phony targets +# +.PHONY: all shared clean doc release demo + +# +# major rule +# +.c.o: + $(CC) $(CFLAGS) -c $< -o $@ + + +all: libg2.a + test -d ./include || mkdir ./include + cp $(INS) ./include/ + +shared: libg2.so.0.$(G2_VERSION) + @echo + + +libg2.a: $(OBJ) + $(AR) $(ARFLAGS) libg2.a $(OBJ) + test ! -n "$(RANLIB)" || $(RANLIB) $@ + +libg2.so.0.$(G2_VERSION): $(OBJ) + ld -shared -soname libg2.so.0 -o $@ $(OBJ) + +install: libg2.a + test -d $(LIBDIR) || mkdir -p $(LIBDIR) + test -d $(INCDIR) || mkdir -p $(INCDIR) + $(INSTALL_DATA) libg2.a $(LIBDIR) + for IFILE in $(INS); do \ + $(INSTALL_DATA) $$IFILE $(INCDIR); \ + done + +release: clean doc + cp ./doc/latex/refman.ps ./doc/g2_refman.ps + cp ./doc/latex/refman.pdf ./doc/g2_refman.pdf + rm -r ./doc/latex + +doc: + (cd ./doc ; doxygen Doxyfile) + (cd ./doc/latex ; make ps ; make pdf) + + +clean: + -(cd ./demo ; make clean) + -rm -f $(OBJ) + -rm -f libg2.a config.cache config.log Makefile.bak config.status + -rm -f ./include/*.h + -$(FIND) . -name "*~" -exec rm -f {} \; + -(cd ./g2_perl ; make clean) + -rm -f ./g2_perl/test.ps + -rm -f ./g2_perl/test.png + -rm -f ./g2_perl/test.jpg + -rm -f ./g2_perl/test.fig + -rm -f ./g2_perl/Makefile.old + -rm -f ./libg2.so.0.$(G2_VERSION) + -rm -f libg2.$(G2_VERSION).a + -rm -f a.out + -rm -fr doc/html/ doc/latex/ doc/g2_refman.ps doc/g2_refman.pdf + +demo: libg2.a + (cd ./demo ; make) + +depend: + $(MAKEDEPEND) -- $(CFLAGS) -- $(SRC) + @echo + @echo "Run 'make' to build g2 library." + @echo + +distdir: + cp -r * $(distdir) + + +# DO NOT DELETE THIS LINE -- make depend depends on it. + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile.in new file mode 100755 index 00000000..025ef5f5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/Makefile.in @@ -0,0 +1,149 @@ +# +# +# Makefile for g2 library +# +# + +G2_VERSION = 0.70 + +# +# g2 installation directories +# +LIBDIR = @prefix@/lib +INCDIR = @prefix@/include + + +#LIBDIR = $(HOME)/local/lib +#INCDIR = $(HOME)/local/include + +# +#------------------------ do not edit ------------------------ +# +SHELL = /bin/sh + +CC = @CC@ +CFLAGS = -I./src @CFLAGS@ @DEFS@ +INSTALL = @INSTALL@ +INSTALL_DATA = @INSTALL_DATA@ +FIND = @FIND@ +MAKEDEPEND = @MAKEDEPEND@ +AR = ar +ARFLAGS = -cr +RANLIB = @RANLIB@ +LD = ld +LDFLAGS = @LDFLAGS@ + + +BASE_DIR = ./src +BASE_SRC = $(BASE_DIR)/g2_device.c $(BASE_DIR)/g2_ui_control.c \ + $(BASE_DIR)/g2_util.c $(BASE_DIR)/g2_fif.c \ + $(BASE_DIR)/g2_virtual_device.c $(BASE_DIR)/g2_physical_device.c \ + $(BASE_DIR)/g2_graphic_pd.c $(BASE_DIR)/g2_control_pd.c \ + $(BASE_DIR)/g2_ui_graphic.c $(BASE_DIR)/g2_ui_virtual_device.c \ + $(BASE_DIR)/g2_ui_device.c $(BASE_DIR)/g2_splines.c +BASE_INS = $(BASE_DIR)/g2.h + + +@DO_PS@PS_DIR = ./src/PS +@DO_PS@PS_SRC = $(PS_DIR)/g2_PS.c +@DO_PS@PS_INS = $(PS_DIR)/g2_PS.h + +@DO_FIG@FIG_DIR = ./src/FIG +@DO_FIG@FIG_SRC = $(FIG_DIR)/g2_FIG.c +@DO_FIG@FIG_INS = $(FIG_DIR)/g2_FIG.h + +@DO_X11@X11_DIR = ./src/X11 +@DO_X11@X11_SRC = $(X11_DIR)/g2_X11.c +@DO_X11@X11_INS = $(X11_DIR)/g2_X11.h + +@DO_WIN32@WIN32_DIR = ./src/WIN32 +@DO_WIN32@WIN32_SRC = $(WIN32_DIR)/g2_win32.c $(WIN32_DIR)/g2_win32_thread.c +@DO_WIN32@WIN32_INS = $(WIN32_DIR)/g2_win32.h + +@DO_GD@GD_DIR = ./src/GD +@DO_GD@GD_SRC = $(GD_DIR)/g2_gd.c +@DO_GD@GD_INS = $(GD_DIR)/g2_gd.h + + +SRC = $(BASE_SRC) $(PS_SRC) $(FIG_SRC) $(X11_SRC) $(WIN32_SRC) $(GD_SRC) +OBJ = $(SRC:.c=.o) + +INS = $(BASE_INS) $(PS_INS) $(FIG_INS) $(X11_INS) $(WIN32_INS) $(GD_INS) + +# +# define some phony targets +# +.PHONY: all shared clean doc release demo + +# +# major rule +# +.c.o: + $(CC) $(CFLAGS) -c $< -o $@ + + +all: libg2.a + test -d ./include || mkdir ./include + cp $(INS) ./include/ + +shared: libg2.@LD_SHARED_EXT@ + @echo + + +libg2.a: $(OBJ) + $(AR) $(ARFLAGS) libg2.a $(OBJ) + test ! -n "$(RANLIB)" || $(RANLIB) $@ + +libg2.@LD_SHARED_EXT@: $(OBJ) + @LD_SHARED@ @LD_SHARED_FLAGS@ -o $@ $(OBJ) @LD_SHARED_OPT@ + +install: libg2.a + test -d $(LIBDIR) || mkdir -p $(LIBDIR) + test -d $(INCDIR) || mkdir -p $(INCDIR) + $(INSTALL_DATA) libg2.a $(LIBDIR) + for IFILE in $(INS); do \ + $(INSTALL_DATA) $$IFILE $(INCDIR); \ + done + +release: clean doc + cp ./doc/latex/refman.ps ./doc/g2_refman.ps + cp ./doc/latex/refman.pdf ./doc/g2_refman.pdf + rm -r ./doc/latex + +doc: + (cd ./doc ; doxygen Doxyfile) + (cd ./doc/latex ; make ps ; make pdf) + + +clean: + -(cd ./demo ; make clean) + -rm -f $(OBJ) + -rm -f libg2.a config.cache config.log Makefile.bak config.status + -rm -f ./include/*.h + -$(FIND) . -name "*~" -exec rm -f {} \; + -(cd ./g2_perl ; make clean) + -rm -f ./g2_perl/test.ps + -rm -f ./g2_perl/test.png + -rm -f ./g2_perl/test.jpg + -rm -f ./g2_perl/test.fig + -rm -f ./g2_perl/Makefile.old + -rm -f ./libg2.@LD_SHARED_EXT@ + -rm -f libg2.$(G2_VERSION).a + -rm -f a.out + -rm -fr doc/html/ doc/latex/ doc/g2_refman.ps doc/g2_refman.pdf + +demo: libg2.a + (cd ./demo ; make) + +depend: + $(MAKEDEPEND) -- $(CFLAGS) -- $(SRC) + @echo + @echo "Run 'make' to build g2 library." + @echo + +distdir: + cp -r * $(distdir) + + +# DO NOT DELETE THIS LINE -- make depend depends on it. + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/README b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/README new file mode 100755 index 00000000..80f0401c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/README @@ -0,0 +1,80 @@ +g2 - graphic library (C) 1999 Lj. Milanovic, H. Wagner + +Version 0.xx + +License Information +=================== + +This library is free software; you can redistribute it and/or +modify it under the terms of the GNU Lesser General Public +License as published by the Free Software Foundation; either +version 2.1 of the License, or (at your option) any later version. + +This library is distributed in the hope that it will be useful, +but WITHOUT ANY WARRANTY; without even the implied warranty of +MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +Lesser General Public License for more details. + +See INSTALL for information on how to install g2 see the html +documentation in the doc/ subdirectory for a function reference + +What is g2 ? +============ + +Short version (if you are in hurry): + + - 2D graphic library + - Simple to use + - Supports several types of output devices (currently X11, + gd (PNG, JPEG), PostScript) + - Concept allows easy implementation of new device types + - Virtual devices allow to send output simultaneously to several devices + - User definable coordinate system + - Written in ANSI-C + - Tested under Digital Unix, AIX, Linux, VMS and Windows NT + - Fortran interface + +Long version: + +g2 is a simple to use graphics library for 2D graphical applications +written in Ansi-C. This library provides a comprehensive set of +functions for simultaneous generation of graphical output on different +types of devices. Presently, following devices are currently supported +by g2: X11, gd (PNG, JPEG), PostScript (xfig and Win32 are in developement). +One major feature of the g2_library is the concept of virtual devices. An +arbitrary number of physical devices (such as PNG, or X11) can be +grouped to create a so-called virtual device. Commands sent to such a +virtual devices will automatically issued to all attached physical +devices. This allows for example simultaneous output to a PNG file and +a Postscript file. A virtual device in turn can be attached to another +virtual device, allowing to construct trees of devices. Virtual +devices can also be useful when using different user-coordinate +systems. E.g. one X11 window showing an overview of a graphical +output, and a second window showing a zoom of a more detailed area of +the graphic. Drawing in both windows is performed by one single +command to the virtual device. + + + /-------> PNG: g2_attach(id_PNG,... + ----------------------- +g2_plot---> | Virtual device: id |--------> X11: g2_attach(id_X11,... + ----------------------- + \-------> PS: g2_attach(id_PS,... + +If you don't need or like the concept of virtual devices, simply ignore it. + + +CONTACT +======= + +You can contact the authors and contributors by e-mail (/ is @ and - is .): + +Ljubomir Milanovic ljubo/users-sourceforge-net +Horst Wagner wagner/users-sourceforge-net +Tijs Michels (spline implementation) tijs/vimec-nl + +or visit g2 home page on: + +http://g2.sourceforge.net/ + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/TODO b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/TODO new file mode 100755 index 00000000..cf294d19 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/TODO @@ -0,0 +1,8 @@ + +- native g2_image support +- gd: setlinedash +- finish xfig support +- test (and add) Fortran interface on more platforms +- new devices (e.g. PNG, JPG, etc.) +- documentation for developement of new devices + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Repository new file mode 100755 index 00000000..c49a15b0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/autom4te.cache diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/output.0 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/output.0 new file mode 100755 index 00000000..de34feaa --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/output.0 @@ -0,0 +1,6602 @@ +@%:@! /bin/sh +@%:@ Guess values for system-dependent variables and create Makefiles. +@%:@ Generated by GNU Autoconf 2.59. +@%:@ +@%:@ Copyright (C) 2003 Free Software Foundation, Inc. +@%:@ This configure script is free software; the Free Software Foundation +@%:@ gives unlimited permission to copy, distribute and modify it. +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. 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Use of quotes ensures accuracy. + *) ac_configure_args="$ac_configure_args '$ac_arg'" ;; + esac + fi +done +if $ac_cache_corrupted; then + { echo "$as_me:$LINENO: error: changes in the environment can compromise the build" >&5 +echo "$as_me: error: changes in the environment can compromise the build" >&2;} + { { echo "$as_me:$LINENO: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&5 +echo "$as_me: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + + + + + + + + + + + + + + + + + + + + +PRODUCT=g2 + + +# +# check cannonical system name, +# and set options for shared libraries (black magic) +# +ac_aux_dir= +for ac_dir in $srcdir $srcdir/.. $srcdir/../..; do + if test -f $ac_dir/install-sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install-sh -c" + break + elif test -f $ac_dir/install.sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install.sh -c" + break + elif test -f $ac_dir/shtool; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/shtool install -c" + break + fi +done +if test -z "$ac_aux_dir"; then + { { echo "$as_me:$LINENO: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&5 +echo "$as_me: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&2;} + { (exit 1); exit 1; }; } +fi +ac_config_guess="$SHELL $ac_aux_dir/config.guess" +ac_config_sub="$SHELL $ac_aux_dir/config.sub" +ac_configure="$SHELL $ac_aux_dir/configure" # This should be Cygnus configure. + +# Make sure we can run config.sub. +$ac_config_sub sun4 >/dev/null 2>&1 || + { { echo "$as_me:$LINENO: error: cannot run $ac_config_sub" >&5 +echo "$as_me: error: cannot run $ac_config_sub" >&2;} + { (exit 1); exit 1; }; } + +echo "$as_me:$LINENO: checking build system type" >&5 +echo $ECHO_N "checking build system type... $ECHO_C" >&6 +if test "${ac_cv_build+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_build_alias=$build_alias +test -z "$ac_cv_build_alias" && + ac_cv_build_alias=`$ac_config_guess` +test -z "$ac_cv_build_alias" && + { { echo "$as_me:$LINENO: error: cannot guess build type; you must specify one" >&5 +echo "$as_me: error: cannot guess build type; you must specify one" >&2;} + { (exit 1); exit 1; }; } +ac_cv_build=`$ac_config_sub $ac_cv_build_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_build_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_build_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_build" >&5 +echo "${ECHO_T}$ac_cv_build" >&6 +build=$ac_cv_build +build_cpu=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +build_vendor=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +build_os=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + +echo "$as_me:$LINENO: checking host system type" >&5 +echo $ECHO_N "checking host system type... $ECHO_C" >&6 +if test "${ac_cv_host+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_host_alias=$host_alias +test -z "$ac_cv_host_alias" && + ac_cv_host_alias=$ac_cv_build_alias +ac_cv_host=`$ac_config_sub $ac_cv_host_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_host_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_host_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_host" >&5 +echo "${ECHO_T}$ac_cv_host" >&6 +host=$ac_cv_host +host_cpu=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +host_vendor=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +host_os=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + +case "$host" in + *-linux*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared -soname libg2.so.0' + LD_SHARED_OPT='' + LD_SHARED_EXT='so.0.$(G2_VERSION)' + cat >>confdefs.h <<\_ACEOF +@%:@define LINUX 1 +_ACEOF +;; + *-aix*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-bM:SRE -bnoentry -bexpall' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +@%:@define AIX 1 +_ACEOF +;; + *-osf*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +@%:@define OSF 1 +_ACEOF +;; + *) + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +@%:@define UNIX 1 +_ACEOF +;; +esac + + + + + + +# +# check C compiler, preprocesor, etc. +# +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args. +set dummy ${ac_tool_prefix}gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "gcc", so it can be a program name with args. +set dummy gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args. +set dummy ${ac_tool_prefix}cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +fi +if test -z "$CC"; then + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else + ac_prog_rejected=no +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then + ac_prog_rejected=yes + continue + fi + ac_cv_prog_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +if test $ac_prog_rejected = yes; then + # We found a bogon in the path, so make sure we never use it. + set dummy $ac_cv_prog_CC + shift + if test $@%:@ != 0; then + # We chose a different compiler from the bogus one. + # However, it has the same basename, so the bogon will be chosen + # first if we set CC to just the basename; use the full file name. + shift + ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@" + fi +fi +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + for ac_prog in cl + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CC" && break + done +fi +if test -z "$CC"; then + ac_ct_CC=$CC + for ac_prog in cl +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CC" && break +done + + CC=$ac_ct_CC +fi + +fi + + +test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&5 +echo "$as_me: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files a.out a.exe b.out" +# Try to create an executable without -o first, disregard a.out. +# It will help us diagnose broken compilers, and finding out an intuition +# of exeext. +echo "$as_me:$LINENO: checking for C compiler default output file name" >&5 +echo $ECHO_N "checking for C compiler default output file name... $ECHO_C" >&6 +ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'` +if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5 + (eval $ac_link_default) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # Find the output, starting from the most likely. This scheme is +# not robust to junk in `.', hence go to wildcards (a.*) only as a last +# resort. + +# Be careful to initialize this variable, since it used to be cached. +# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile. +ac_cv_exeext= +# b.out is created by i960 compilers. +for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out +do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) + ;; + conftest.$ac_ext ) + # This is the source file. + ;; + [ab].out ) + # We found the default executable, but exeext='' is most + # certainly right. + break;; + *.* ) + ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + # FIXME: I believe we export ac_cv_exeext for Libtool, + # but it would be cool to find out if it's true. Does anybody + # maintain Libtool? --akim. + export ac_cv_exeext + break;; + * ) + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: C compiler cannot create executables +See \`config.log' for more details." >&5 +echo "$as_me: error: C compiler cannot create executables +See \`config.log' for more details." >&2;} + { (exit 77); exit 77; }; } +fi + +ac_exeext=$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_file" >&5 +echo "${ECHO_T}$ac_file" >&6 + +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether the C compiler works" >&5 +echo $ECHO_N "checking whether the C compiler works... $ECHO_C" >&6 +# FIXME: These cross compiler hacks should be removed for Autoconf 3.0 +# If not cross compiling, check that we can run a simple program. +if test "$cross_compiling" != yes; then + if { ac_try='./$ac_file' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + cross_compiling=no + else + if test "$cross_compiling" = maybe; then + cross_compiling=yes + else + { { echo "$as_me:$LINENO: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + fi + fi +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +rm -f a.out a.exe conftest$ac_cv_exeext b.out +ac_clean_files=$ac_clean_files_save +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether we are cross compiling" >&5 +echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6 +echo "$as_me:$LINENO: result: $cross_compiling" >&5 +echo "${ECHO_T}$cross_compiling" >&6 + +echo "$as_me:$LINENO: checking for suffix of executables" >&5 +echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6 +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # If both `conftest.exe' and `conftest' are `present' (well, observable) +# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will +# work properly (i.e., refer to `conftest.exe'), while it won't with +# `rm'. +for ac_file in conftest.exe conftest conftest.*; do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;; + *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + export ac_cv_exeext + break;; + * ) break;; + esac +done +else + { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5 +echo "${ECHO_T}$ac_cv_exeext" >&6 + +rm -f conftest.$ac_ext +EXEEXT=$ac_cv_exeext +ac_exeext=$EXEEXT +echo "$as_me:$LINENO: checking for suffix of object files" >&5 +echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6 +if test "${ac_cv_objext+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.o conftest.obj +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;; + *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'` + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest.$ac_cv_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_objext" >&5 +echo "${ECHO_T}$ac_cv_objext" >&6 +OBJEXT=$ac_cv_objext +ac_objext=$OBJEXT +echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6 +if test "${ac_cv_c_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_c_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6 +GCC=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CFLAGS=${CFLAGS+set} +ac_save_CFLAGS=$CFLAGS +CFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5 +echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cc_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_g" >&6 +if test "$ac_test_CFLAGS" = set; then + CFLAGS=$ac_save_CFLAGS +elif test $ac_cv_prog_cc_g = yes; then + if test "$GCC" = yes; then + CFLAGS="-g -O2" + else + CFLAGS="-g" + fi +else + if test "$GCC" = yes; then + CFLAGS="-O2" + else + CFLAGS= + fi +fi +echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5 +echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_prog_cc_stdc=no +ac_save_CC=$CC +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include +/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */ +struct buf { int x; }; +FILE * (*rcsopen) (struct buf *, struct stat *, int); +static char *e (p, i) + char **p; + int i; +{ + return p[i]; +} +static char *f (char * (*g) (char **, int), char **p, ...) +{ + char *s; + va_list v; + va_start (v,p); + s = g (p, va_arg (v,int)); + va_end (v); + return s; +} + +/* OSF 4.0 Compaq cc is some sort of almost-ANSI by default. It has + function prototypes and stuff, but not '\xHH' hex character constants. + These don't provoke an error unfortunately, instead are silently treated + as 'x'. The following induces an error, until -std1 is added to get + proper ANSI mode. Curiously '\x00'!='x' always comes out true, for an + array size at least. It's necessary to write '\x00'==0 to get something + that's true only with -std1. */ +int osf4_cc_array ['\x00' == 0 ? 1 : -1]; + +int test (int i, double x); +struct s1 {int (*f) (int a);}; +struct s2 {int (*f) (double a);}; +int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int); +int argc; +char **argv; +int +main () +{ +return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1]; + ; + return 0; +} +_ACEOF +# Don't try gcc -ansi; that turns off useful extensions and +# breaks some systems' header files. +# AIX -qlanglvl=ansi +# Ultrix and OSF/1 -std1 +# HP-UX 10.20 and later -Ae +# HP-UX older versions -Aa -D_HPUX_SOURCE +# SVR4 -Xc -D__EXTENSIONS__ +for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__" +do + CC="$ac_save_CC $ac_arg" + rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_stdc=$ac_arg +break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext +done +rm -f conftest.$ac_ext conftest.$ac_objext +CC=$ac_save_CC + +fi + +case "x$ac_cv_prog_cc_stdc" in + x|xno) + echo "$as_me:$LINENO: result: none needed" >&5 +echo "${ECHO_T}none needed" >&6 ;; + *) + echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6 + CC="$CC $ac_cv_prog_cc_stdc" ;; +esac + +# Some people use a C++ compiler to compile C. Since we use `exit', +# in C++ we need to declare it. In case someone uses the same compiler +# for both compiling C and C++ we need to have the C++ compiler decide +# the declaration of exit, since it's the most demanding environment. +cat >conftest.$ac_ext <<_ACEOF +@%:@ifndef __cplusplus + choke me +@%:@endif +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +@%:@include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +echo "$as_me:$LINENO: checking how to run the C preprocessor" >&5 +echo $ECHO_N "checking how to run the C preprocessor... $ECHO_C" >&6 +# On Suns, sometimes $CPP names a directory. +if test -n "$CPP" && test -d "$CPP"; then + CPP= +fi +if test -z "$CPP"; then + if test "${ac_cv_prog_CPP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # Double quotes because CPP needs to be expanded + for CPP in "$CC -E" "$CC -E -traditional-cpp" "/lib/cpp" + do + ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@ifdef __STDC__ +@%:@ include +@%:@else +@%:@ include +@%:@endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + break +fi + + done + ac_cv_prog_CPP=$CPP + +fi + CPP=$ac_cv_prog_CPP +else + ac_cv_prog_CPP=$CPP +fi +echo "$as_me:$LINENO: result: $CPP" >&5 +echo "${ECHO_T}$CPP" >&6 +ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@ifdef __STDC__ +@%:@ include +@%:@else +@%:@ include +@%:@endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + : +else + { { echo "$as_me:$LINENO: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&5 +echo "$as_me: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu +if test -n "$ac_tool_prefix"; then + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CXX"; then + ac_cv_prog_CXX="$CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CXX="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CXX=$ac_cv_prog_CXX +if test -n "$CXX"; then + echo "$as_me:$LINENO: result: $CXX" >&5 +echo "${ECHO_T}$CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CXX" && break + done +fi +if test -z "$CXX"; then + ac_ct_CXX=$CXX + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CXX"; then + ac_cv_prog_ac_ct_CXX="$ac_ct_CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CXX="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CXX=$ac_cv_prog_ac_ct_CXX +if test -n "$ac_ct_CXX"; then + echo "$as_me:$LINENO: result: $ac_ct_CXX" >&5 +echo "${ECHO_T}$ac_ct_CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CXX" && break +done +test -n "$ac_ct_CXX" || ac_ct_CXX="g++" + + CXX=$ac_ct_CXX +fi + + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C++ compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +echo "$as_me:$LINENO: checking whether we are using the GNU C++ compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C++ compiler... $ECHO_C" >&6 +if test "${ac_cv_cxx_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_cxx_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_cxx_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_cxx_compiler_gnu" >&6 +GXX=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CXXFLAGS=${CXXFLAGS+set} +ac_save_CXXFLAGS=$CXXFLAGS +CXXFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CXX accepts -g" >&5 +echo $ECHO_N "checking whether $CXX accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cxx_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cxx_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cxx_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cxx_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cxx_g" >&6 +if test "$ac_test_CXXFLAGS" = set; then + CXXFLAGS=$ac_save_CXXFLAGS +elif test $ac_cv_prog_cxx_g = yes; then + if test "$GXX" = yes; then + CXXFLAGS="-g -O2" + else + CXXFLAGS="-g" + fi +else + if test "$GXX" = yes; then + CXXFLAGS="-O2" + else + CXXFLAGS= + fi +fi +for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +@%:@include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}ranlib", so it can be a program name with args. +set dummy ${ac_tool_prefix}ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$RANLIB"; then + ac_cv_prog_RANLIB="$RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_RANLIB="${ac_tool_prefix}ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +RANLIB=$ac_cv_prog_RANLIB +if test -n "$RANLIB"; then + echo "$as_me:$LINENO: result: $RANLIB" >&5 +echo "${ECHO_T}$RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_RANLIB"; then + ac_ct_RANLIB=$RANLIB + # Extract the first word of "ranlib", so it can be a program name with args. +set dummy ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_RANLIB"; then + ac_cv_prog_ac_ct_RANLIB="$ac_ct_RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_RANLIB="ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_RANLIB" && ac_cv_prog_ac_ct_RANLIB=":" +fi +fi +ac_ct_RANLIB=$ac_cv_prog_ac_ct_RANLIB +if test -n "$ac_ct_RANLIB"; then + echo "$as_me:$LINENO: result: $ac_ct_RANLIB" >&5 +echo "${ECHO_T}$ac_ct_RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + RANLIB=$ac_ct_RANLIB +else + RANLIB="$ac_cv_prog_RANLIB" +fi + +# Find a good install program. We prefer a C program (faster), +# so one script is as good as another. But avoid the broken or +# incompatible versions: +# SysV /etc/install, /usr/sbin/install +# SunOS /usr/etc/install +# IRIX /sbin/install +# AIX /bin/install +# AmigaOS /C/install, which installs bootblocks on floppy discs +# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag +# AFS /usr/afsws/bin/install, which mishandles nonexistent args +# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff" +# OS/2's system install, which has a completely different semantic +# ./install, which can be erroneously created by make from ./install.sh. +echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5 +echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6 +if test -z "$INSTALL"; then +if test "${ac_cv_path_install+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + # Account for people who put trailing slashes in PATH elements. +case $as_dir/ in + ./ | .// | /cC/* | \ + /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \ + ?:\\/os2\\/install\\/* | ?:\\/OS2\\/INSTALL\\/* | \ + /usr/ucb/* ) ;; + *) + # OSF1 and SCO ODT 3.0 have their own names for install. + # Don't use installbsd from OSF since it installs stuff as root + # by default. + for ac_prog in ginstall scoinst install; do + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then + if test $ac_prog = install && + grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # AIX install. It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +# Extract the first word of "find", so it can be a program name with args. +set dummy find; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_FIND+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$FIND"; then + ac_cv_prog_FIND="$FIND" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_FIND="find" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_FIND" && ac_cv_prog_FIND=":" +fi +fi +FIND=$ac_cv_prog_FIND +if test -n "$FIND"; then + echo "$as_me:$LINENO: result: $FIND" >&5 +echo "${ECHO_T}$FIND" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +# Extract the first word of "makedepend", so it can be a program name with args. +set dummy makedepend; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_MAKEDEPEND+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$MAKEDEPEND"; then + ac_cv_prog_MAKEDEPEND="$MAKEDEPEND" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_MAKEDEPEND="makedepend" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_MAKEDEPEND" && ac_cv_prog_MAKEDEPEND=":" +fi +fi +MAKEDEPEND=$ac_cv_prog_MAKEDEPEND +if test -n "$MAKEDEPEND"; then + echo "$as_me:$LINENO: result: $MAKEDEPEND" >&5 +echo "${ECHO_T}$MAKEDEPEND" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + +echo "$as_me:$LINENO: checking for dlopen in -ldl" >&5 +echo $ECHO_N "checking for dlopen in -ldl... $ECHO_C" >&6 +if test "${ac_cv_lib_dl_dlopen+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldl $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dlopen (); +int +main () +{ +dlopen (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dl_dlopen=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dl_dlopen=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dl_dlopen" >&5 +echo "${ECHO_T}$ac_cv_lib_dl_dlopen" >&6 +if test $ac_cv_lib_dl_dlopen = yes; then + have_dl=yes +else + have_dl=no +fi + + + +# +# Try to locate the X Window System include files and libraries +# and add /usr/local to include and lib path and add -lm (for testing) +# + +echo "$as_me:$LINENO: checking for X" >&5 +echo $ECHO_N "checking for X... $ECHO_C" >&6 + + +# Check whether --with-x or --without-x was given. +if test "${with_x+set}" = set; then + withval="$with_x" + +fi; +# $have_x is `yes', `no', `disabled', or empty when we do not yet know. +if test "x$with_x" = xno; then + # The user explicitly disabled X. + have_x=disabled +else + if test "x$x_includes" != xNONE && test "x$x_libraries" != xNONE; then + # Both variables are already set. + have_x=yes + else + if test "${ac_cv_have_x+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # One or both of the vars are not set, and there is no cached value. +ac_x_includes=no ac_x_libraries=no +rm -fr conftest.dir +if mkdir conftest.dir; then + cd conftest.dir + # Make sure to not put "make" in the Imakefile rules, since we grep it out. + cat >Imakefile <<'_ACEOF' +acfindx: + @echo 'ac_im_incroot="${INCROOT}"; ac_im_usrlibdir="${USRLIBDIR}"; ac_im_libdir="${LIBDIR}"' +_ACEOF + if (xmkmf) >/dev/null 2>/dev/null && test -f Makefile; then + # GNU make sometimes prints "make[1]: Entering...", which would confuse us. + eval `${MAKE-make} acfindx 2>/dev/null | grep -v make` + # Open Windows xmkmf reportedly sets LIBDIR instead of USRLIBDIR. + for ac_extension in a so sl; do + if test ! -f $ac_im_usrlibdir/libX11.$ac_extension && + test -f $ac_im_libdir/libX11.$ac_extension; then + ac_im_usrlibdir=$ac_im_libdir; break + fi + done + # Screen out bogus values from the imake configuration. They are + # bogus both because they are the default anyway, and because + # using them would break gcc on systems where it needs fixed includes. + case $ac_im_incroot in + /usr/include) ;; + *) test -f "$ac_im_incroot/X11/Xos.h" && ac_x_includes=$ac_im_incroot;; + esac + case $ac_im_usrlibdir in + /usr/lib | /lib) ;; + *) test -d "$ac_im_usrlibdir" && ac_x_libraries=$ac_im_usrlibdir ;; + esac + fi + cd .. + rm -fr conftest.dir +fi + +# Standard set of common directories for X headers. +# Check X11 before X11Rn because it is often a symlink to the current release. +ac_x_header_dirs=' +/usr/X11/include +/usr/X11R6/include +/usr/X11R5/include +/usr/X11R4/include + +/usr/include/X11 +/usr/include/X11R6 +/usr/include/X11R5 +/usr/include/X11R4 + +/usr/local/X11/include +/usr/local/X11R6/include +/usr/local/X11R5/include +/usr/local/X11R4/include + +/usr/local/include/X11 +/usr/local/include/X11R6 +/usr/local/include/X11R5 +/usr/local/include/X11R4 + +/usr/X386/include +/usr/x386/include +/usr/XFree86/include/X11 + +/usr/include +/usr/local/include +/usr/unsupported/include +/usr/athena/include +/usr/local/x11r5/include +/usr/lpp/Xamples/include + +/usr/openwin/include +/usr/openwin/share/include' + +if test "$ac_x_includes" = no; then + # Guess where to find include files, by looking for Intrinsic.h. + # First, try using that file with no special directory specified. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # We can compile using X headers with no special include directory. +ac_x_includes= +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + for ac_dir in $ac_x_header_dirs; do + if test -r "$ac_dir/X11/Intrinsic.h"; then + ac_x_includes=$ac_dir + break + fi +done +fi +rm -f conftest.err conftest.$ac_ext +fi # $ac_x_includes = no + +if test "$ac_x_libraries" = no; then + # Check for the libraries. + # See if we find them without any special options. + # Don't add to $LIBS permanently. + ac_save_LIBS=$LIBS + LIBS="-lXt $LIBS" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@include +int +main () +{ +XtMalloc (0) + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + LIBS=$ac_save_LIBS +# We can link X programs with no special library path. +ac_x_libraries= +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +LIBS=$ac_save_LIBS +for ac_dir in `echo "$ac_x_includes $ac_x_header_dirs" | sed s/include/lib/g` +do + # Don't even attempt the hair of trying to link an X program! + for ac_extension in a so sl; do + if test -r $ac_dir/libXt.$ac_extension; then + ac_x_libraries=$ac_dir + break 2 + fi + done +done +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi # $ac_x_libraries = no + +if test "$ac_x_includes" = no || test "$ac_x_libraries" = no; then + # Didn't find X anywhere. Cache the known absence of X. + ac_cv_have_x="have_x=no" +else + # Record where we found X for the cache. + ac_cv_have_x="have_x=yes \ + ac_x_includes=$ac_x_includes ac_x_libraries=$ac_x_libraries" +fi +fi + + fi + eval "$ac_cv_have_x" +fi # $with_x != no + +if test "$have_x" != yes; then + echo "$as_me:$LINENO: result: $have_x" >&5 +echo "${ECHO_T}$have_x" >&6 + no_x=yes +else + # If each of the values was on the command line, it overrides each guess. + test "x$x_includes" = xNONE && x_includes=$ac_x_includes + test "x$x_libraries" = xNONE && x_libraries=$ac_x_libraries + # Update the cache value to reflect the command line values. + ac_cv_have_x="have_x=yes \ + ac_x_includes=$x_includes ac_x_libraries=$x_libraries" + echo "$as_me:$LINENO: result: libraries $x_libraries, headers $x_includes" >&5 +echo "${ECHO_T}libraries $x_libraries, headers $x_includes" >&6 +fi + +if test "$no_x" = yes; then + # Not all programs may use this symbol, but it does not hurt to define it. + +cat >>confdefs.h <<\_ACEOF +@%:@define X_DISPLAY_MISSING 1 +_ACEOF + + X_CFLAGS= X_PRE_LIBS= X_LIBS= X_EXTRA_LIBS= +else + if test -n "$x_includes"; then + X_CFLAGS="$X_CFLAGS -I$x_includes" + fi + + # It would also be nice to do this for all -L options, not just this one. + if test -n "$x_libraries"; then + X_LIBS="$X_LIBS -L$x_libraries" + # For Solaris; some versions of Sun CC require a space after -R and + # others require no space. Words are not sufficient . . . . + case `(uname -sr) 2>/dev/null` in + "SunOS 5"*) + echo "$as_me:$LINENO: checking whether -R must be followed by a space" >&5 +echo $ECHO_N "checking whether -R must be followed by a space... $ECHO_C" >&6 + ac_xsave_LIBS=$LIBS; LIBS="$LIBS -R$x_libraries" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_R_nospace=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_R_nospace=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + if test $ac_R_nospace = yes; then + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + X_LIBS="$X_LIBS -R$x_libraries" + else + LIBS="$ac_xsave_LIBS -R $x_libraries" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_R_space=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_R_space=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + if test $ac_R_space = yes; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + X_LIBS="$X_LIBS -R $x_libraries" + else + echo "$as_me:$LINENO: result: neither works" >&5 +echo "${ECHO_T}neither works" >&6 + fi + fi + LIBS=$ac_xsave_LIBS + esac + fi + + # Check for system-dependent libraries X programs must link with. + # Do this before checking for the system-independent R6 libraries + # (-lICE), since we may need -lsocket or whatever for X linking. + + if test "$ISC" = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lnsl_s -linet" + else + # Martyn Johnson says this is needed for Ultrix, if the X + # libraries were built with DECnet support. And Karl Berry says + # the Alpha needs dnet_stub (dnet does not exist). + ac_xsave_LIBS="$LIBS"; LIBS="$LIBS $X_LIBS -lX11" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char XOpenDisplay (); +int +main () +{ +XOpenDisplay (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +echo "$as_me:$LINENO: checking for dnet_ntoa in -ldnet" >&5 +echo $ECHO_N "checking for dnet_ntoa in -ldnet... $ECHO_C" >&6 +if test "${ac_cv_lib_dnet_dnet_ntoa+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldnet $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dnet_ntoa (); +int +main () +{ +dnet_ntoa (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dnet_dnet_ntoa=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dnet_dnet_ntoa=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dnet_dnet_ntoa" >&5 +echo "${ECHO_T}$ac_cv_lib_dnet_dnet_ntoa" >&6 +if test $ac_cv_lib_dnet_dnet_ntoa = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -ldnet" +fi + + if test $ac_cv_lib_dnet_dnet_ntoa = no; then + echo "$as_me:$LINENO: checking for dnet_ntoa in -ldnet_stub" >&5 +echo $ECHO_N "checking for dnet_ntoa in -ldnet_stub... $ECHO_C" >&6 +if test "${ac_cv_lib_dnet_stub_dnet_ntoa+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldnet_stub $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dnet_ntoa (); +int +main () +{ +dnet_ntoa (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dnet_stub_dnet_ntoa=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dnet_stub_dnet_ntoa=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dnet_stub_dnet_ntoa" >&5 +echo "${ECHO_T}$ac_cv_lib_dnet_stub_dnet_ntoa" >&6 +if test $ac_cv_lib_dnet_stub_dnet_ntoa = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -ldnet_stub" +fi + + fi +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + LIBS="$ac_xsave_LIBS" + + # msh@cis.ufl.edu says -lnsl (and -lsocket) are needed for his 386/AT, + # to get the SysV transport functions. + # Chad R. Larson says the Pyramis MIS-ES running DC/OSx (SVR4) + # needs -lnsl. + # The nsl library prevents programs from opening the X display + # on Irix 5.2, according to T.E. Dickey. + # The functions gethostbyname, getservbyname, and inet_addr are + # in -lbsd on LynxOS 3.0.1/i386, according to Lars Hecking. + echo "$as_me:$LINENO: checking for gethostbyname" >&5 +echo $ECHO_N "checking for gethostbyname... $ECHO_C" >&6 +if test "${ac_cv_func_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gethostbyname to an innocuous variant, in case declares gethostbyname. + For example, HP-UX 11i declares gettimeofday. */ +#define gethostbyname innocuous_gethostbyname + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gethostbyname (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gethostbyname + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gethostbyname) || defined (__stub___gethostbyname) +choke me +#else +char (*f) () = gethostbyname; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gethostbyname; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_func_gethostbyname" >&6 + + if test $ac_cv_func_gethostbyname = no; then + echo "$as_me:$LINENO: checking for gethostbyname in -lnsl" >&5 +echo $ECHO_N "checking for gethostbyname in -lnsl... $ECHO_C" >&6 +if test "${ac_cv_lib_nsl_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lnsl $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +int +main () +{ +gethostbyname (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_nsl_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_nsl_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_nsl_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_lib_nsl_gethostbyname" >&6 +if test $ac_cv_lib_nsl_gethostbyname = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lnsl" +fi + + if test $ac_cv_lib_nsl_gethostbyname = no; then + echo "$as_me:$LINENO: checking for gethostbyname in -lbsd" >&5 +echo $ECHO_N "checking for gethostbyname in -lbsd... $ECHO_C" >&6 +if test "${ac_cv_lib_bsd_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lbsd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +int +main () +{ +gethostbyname (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_bsd_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_bsd_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_bsd_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_lib_bsd_gethostbyname" >&6 +if test $ac_cv_lib_bsd_gethostbyname = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lbsd" +fi + + fi + fi + + # lieder@skyler.mavd.honeywell.com says without -lsocket, + # socket/setsockopt and other routines are undefined under SCO ODT + # 2.0. But -lsocket is broken on IRIX 5.2 (and is not necessary + # on later versions), says Simon Leinen: it contains gethostby* + # variants that don't use the name server (or something). -lsocket + # must be given before -lnsl if both are needed. We assume that + # if connect needs -lnsl, so does gethostbyname. + echo "$as_me:$LINENO: checking for connect" >&5 +echo $ECHO_N "checking for connect... $ECHO_C" >&6 +if test "${ac_cv_func_connect+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define connect to an innocuous variant, in case declares connect. + For example, HP-UX 11i declares gettimeofday. */ +#define connect innocuous_connect + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char connect (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef connect + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char connect (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_connect) || defined (__stub___connect) +choke me +#else +char (*f) () = connect; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != connect; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_connect=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_connect=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_connect" >&5 +echo "${ECHO_T}$ac_cv_func_connect" >&6 + + if test $ac_cv_func_connect = no; then + echo "$as_me:$LINENO: checking for connect in -lsocket" >&5 +echo $ECHO_N "checking for connect in -lsocket... $ECHO_C" >&6 +if test "${ac_cv_lib_socket_connect+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lsocket $X_EXTRA_LIBS $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char connect (); +int +main () +{ +connect (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_socket_connect=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_socket_connect=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_socket_connect" >&5 +echo "${ECHO_T}$ac_cv_lib_socket_connect" >&6 +if test $ac_cv_lib_socket_connect = yes; then + X_EXTRA_LIBS="-lsocket $X_EXTRA_LIBS" +fi + + fi + + # Guillermo Gomez says -lposix is necessary on A/UX. + echo "$as_me:$LINENO: checking for remove" >&5 +echo $ECHO_N "checking for remove... $ECHO_C" >&6 +if test "${ac_cv_func_remove+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define remove to an innocuous variant, in case declares remove. + For example, HP-UX 11i declares gettimeofday. */ +#define remove innocuous_remove + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char remove (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef remove + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char remove (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_remove) || defined (__stub___remove) +choke me +#else +char (*f) () = remove; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != remove; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_remove=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_remove=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_remove" >&5 +echo "${ECHO_T}$ac_cv_func_remove" >&6 + + if test $ac_cv_func_remove = no; then + echo "$as_me:$LINENO: checking for remove in -lposix" >&5 +echo $ECHO_N "checking for remove in -lposix... $ECHO_C" >&6 +if test "${ac_cv_lib_posix_remove+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lposix $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char remove (); +int +main () +{ +remove (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_posix_remove=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_posix_remove=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_posix_remove" >&5 +echo "${ECHO_T}$ac_cv_lib_posix_remove" >&6 +if test $ac_cv_lib_posix_remove = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lposix" +fi + + fi + + # BSDI BSD/OS 2.1 needs -lipc for XOpenDisplay. + echo "$as_me:$LINENO: checking for shmat" >&5 +echo $ECHO_N "checking for shmat... $ECHO_C" >&6 +if test "${ac_cv_func_shmat+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define shmat to an innocuous variant, in case declares shmat. + For example, HP-UX 11i declares gettimeofday. */ +#define shmat innocuous_shmat + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char shmat (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef shmat + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char shmat (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_shmat) || defined (__stub___shmat) +choke me +#else +char (*f) () = shmat; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != shmat; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_shmat=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_shmat=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_shmat" >&5 +echo "${ECHO_T}$ac_cv_func_shmat" >&6 + + if test $ac_cv_func_shmat = no; then + echo "$as_me:$LINENO: checking for shmat in -lipc" >&5 +echo $ECHO_N "checking for shmat in -lipc... $ECHO_C" >&6 +if test "${ac_cv_lib_ipc_shmat+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lipc $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char shmat (); +int +main () +{ +shmat (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_ipc_shmat=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_ipc_shmat=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_ipc_shmat" >&5 +echo "${ECHO_T}$ac_cv_lib_ipc_shmat" >&6 +if test $ac_cv_lib_ipc_shmat = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lipc" +fi + + fi + fi + + # Check for libraries that X11R6 Xt/Xaw programs need. + ac_save_LDFLAGS=$LDFLAGS + test -n "$x_libraries" && LDFLAGS="$LDFLAGS -L$x_libraries" + # SM needs ICE to (dynamically) link under SunOS 4.x (so we have to + # check for ICE first), but we must link in the order -lSM -lICE or + # we get undefined symbols. So assume we have SM if we have ICE. + # These have to be linked with before -lX11, unlike the other + # libraries we check for below, so use a different variable. + # John Interrante, Karl Berry + echo "$as_me:$LINENO: checking for IceConnectionNumber in -lICE" >&5 +echo $ECHO_N "checking for IceConnectionNumber in -lICE... $ECHO_C" >&6 +if test "${ac_cv_lib_ICE_IceConnectionNumber+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lICE $X_EXTRA_LIBS $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char IceConnectionNumber (); +int +main () +{ +IceConnectionNumber (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_ICE_IceConnectionNumber=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_ICE_IceConnectionNumber=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_ICE_IceConnectionNumber" >&5 +echo "${ECHO_T}$ac_cv_lib_ICE_IceConnectionNumber" >&6 +if test $ac_cv_lib_ICE_IceConnectionNumber = yes; then + X_PRE_LIBS="$X_PRE_LIBS -lSM -lICE" +fi + + LDFLAGS=$ac_save_LDFLAGS + +fi + +CFLAGS="$CFLAGS $X_CFLAGS -I/usr/local/include" +LDFLAGS="$LDFLAGS $X_LIBS -L/usr/local/lib" + + +DO_PS='#' +DO_FIG='#' +DO_X11='#' +DO_GD='#' +DO_WIN32='#' + + +# +# check supported devices +# +echo "$as_me:$LINENO: checking for main in -lm" >&5 +echo $ECHO_N "checking for main in -lm... $ECHO_C" >&6 +if test "${ac_cv_lib_m_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lm $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_m_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_m_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_m_main" >&5 +echo "${ECHO_T}$ac_cv_lib_m_main" >&6 +if test $ac_cv_lib_m_main = yes; then + DO_PS='';DO_FIG='';LDFLAGS="$LDFLAGS -lm";cat >>confdefs.h <<\_ACEOF +@%:@define DO_PS 1 +_ACEOF + cat >>confdefs.h <<\_ACEOF +@%:@define DO_FIG 1 +_ACEOF + +else + break +fi + +echo "$as_me:$LINENO: checking for main in -lX11" >&5 +echo $ECHO_N "checking for main in -lX11... $ECHO_C" >&6 +if test "${ac_cv_lib_X11_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lX11 $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_X11_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_X11_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_X11_main" >&5 +echo "${ECHO_T}$ac_cv_lib_X11_main" >&6 +if test $ac_cv_lib_X11_main = yes; then + DO_X11='';LDFLAGS="$LDFLAGS -lX11";cat >>confdefs.h <<\_ACEOF +@%:@define DO_X11 1 +_ACEOF + +fi + +echo "$as_me:$LINENO: checking for main in -lgd" >&5 +echo $ECHO_N "checking for main in -lgd... $ECHO_C" >&6 +if test "${ac_cv_lib_gd_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lgd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_gd_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_gd_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_gd_main" >&5 +echo "${ECHO_T}$ac_cv_lib_gd_main" >&6 +if test $ac_cv_lib_gd_main = yes; then + have_gd=yes +else + have_gd=no +fi + +if test "$have_gd" = yes +then + LDFLAGS="$LDFLAGS -lgd" + echo "$as_me:$LINENO: checking for gdImagePng" >&5 +echo $ECHO_N "checking for gdImagePng... $ECHO_C" >&6 +if test "${ac_cv_func_gdImagePng+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gdImagePng to an innocuous variant, in case declares gdImagePng. + For example, HP-UX 11i declares gettimeofday. */ +#define gdImagePng innocuous_gdImagePng + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gdImagePng (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gdImagePng + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gdImagePng (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gdImagePng) || defined (__stub___gdImagePng) +choke me +#else +char (*f) () = gdImagePng; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gdImagePng; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gdImagePng=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gdImagePng=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gdImagePng" >&5 +echo "${ECHO_T}$ac_cv_func_gdImagePng" >&6 +if test $ac_cv_func_gdImagePng = yes; then + DO_GD='';cat >>confdefs.h <<\_ACEOF +@%:@define DO_GD 1 +_ACEOF + +fi + +fi + +# +# handling cygwin environment (and gd for cygwin == bgd) +# + +case $host_os in + *cygwin* ) CYGWIN=yes;; + * ) CYGWIN=no;; +esac + +if test "$CYGWIN" = yes +then + LDFLAGS="$LDFLAGS -L/lib/w32api" + echo "$as_me:$LINENO: checking for main in -lgdi32" >&5 +echo $ECHO_N "checking for main in -lgdi32... $ECHO_C" >&6 +if test "${ac_cv_lib_gdi32_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lgdi32 $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_gdi32_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_gdi32_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_gdi32_main" >&5 +echo "${ECHO_T}$ac_cv_lib_gdi32_main" >&6 +if test $ac_cv_lib_gdi32_main = yes; then + DO_WIN32='';LDFLAGS="$LDFLAGS -lgdi32";cat >>confdefs.h <<\_ACEOF +@%:@define DO_WIN32 1 +_ACEOF + +fi + + echo "$as_me:$LINENO: checking for main in -lbgd" >&5 +echo $ECHO_N "checking for main in -lbgd... $ECHO_C" >&6 +if test "${ac_cv_lib_bgd_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lbgd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_bgd_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_bgd_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_bgd_main" >&5 +echo "${ECHO_T}$ac_cv_lib_bgd_main" >&6 +if test $ac_cv_lib_bgd_main = yes; then + have_bgd=yes +else + have_bgd=no +fi + + if test "$have_bgd" = yes + then + LDFLAGS="$LDFLAGS -lbgd" + echo "$as_me:$LINENO: checking for gdImagePng" >&5 +echo $ECHO_N "checking for gdImagePng... $ECHO_C" >&6 +if test "${ac_cv_func_gdImagePng+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gdImagePng to an innocuous variant, in case declares gdImagePng. + For example, HP-UX 11i declares gettimeofday. */ +#define gdImagePng innocuous_gdImagePng + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gdImagePng (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gdImagePng + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gdImagePng (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gdImagePng) || defined (__stub___gdImagePng) +choke me +#else +char (*f) () = gdImagePng; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gdImagePng; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gdImagePng=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gdImagePng=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gdImagePng" >&5 +echo "${ECHO_T}$ac_cv_func_gdImagePng" >&6 +if test $ac_cv_func_gdImagePng = yes; then + DO_GD='';cat >>confdefs.h <<\_ACEOF +@%:@define DO_GD 1 +_ACEOF + +fi + + fi +fi + +# +# Declare variables which we want substituted in the Makefile.in's +# + + + + + + +echo "$as_me:$LINENO: checking for egrep" >&5 +echo $ECHO_N "checking for egrep... $ECHO_C" >&6 +if test "${ac_cv_prog_egrep+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if echo a | (grep -E '(a|b)') >/dev/null 2>&1 + then ac_cv_prog_egrep='grep -E' + else ac_cv_prog_egrep='egrep' + fi +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5 +echo "${ECHO_T}$ac_cv_prog_egrep" >&6 + EGREP=$ac_cv_prog_egrep + + +echo "$as_me:$LINENO: checking for ANSI C header files" >&5 +echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6 +if test "${ac_cv_header_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_header_stdc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_header_stdc=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + +if test $ac_cv_header_stdc = yes; then + # SunOS 4.x string.h does not declare mem*, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "memchr" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "free" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi. + if test "$cross_compiling" = yes; then + : +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#if ((' ' & 0x0FF) == 0x020) +# define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +#else +# define ISLOWER(c) \ + (('a' <= (c) && (c) <= 'i') \ + || ('j' <= (c) && (c) <= 'r') \ + || ('s' <= (c) && (c) <= 'z')) +# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +#endif + +#define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +int +main () +{ + int i; + for (i = 0; i < 256; i++) + if (XOR (islower (i), ISLOWER (i)) + || toupper (i) != TOUPPER (i)) + exit(2); + exit (0); +} +_ACEOF +rm -f conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && { ac_try='./conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: program exited with status $ac_status" >&5 +echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +( exit $ac_status ) +ac_cv_header_stdc=no +fi +rm -f core *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext +fi +fi +fi +echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5 +echo "${ECHO_T}$ac_cv_header_stdc" >&6 +if test $ac_cv_header_stdc = yes; then + +cat >>confdefs.h <<\_ACEOF +@%:@define STDC_HEADERS 1 +_ACEOF + +fi + +# On IRIX 5.3, sys/types and inttypes.h are conflicting. + + + + + + + + + +for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default + +@%:@include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_Header=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_Header=no" +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +@%:@define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + +for ac_header in limits.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +else + # Is the header compilable? +echo "$as_me:$LINENO: checking $ac_header usability" >&5 +echo $ECHO_N "checking $ac_header usability... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +@%:@include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_header_compiler=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_header_compiler=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_compiler" >&5 +echo "${ECHO_T}$ac_header_compiler" >&6 + +# Is the header present? +echo "$as_me:$LINENO: checking $ac_header presence" >&5 +echo $ECHO_N "checking $ac_header presence... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +@%:@include <$ac_header> +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + ac_header_preproc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + ac_header_preproc=no +fi +rm -f conftest.err conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_preproc" >&5 +echo "${ECHO_T}$ac_header_preproc" >&6 + +# So? What about this header? +case $ac_header_compiler:$ac_header_preproc:$ac_c_preproc_warn_flag in + yes:no: ) + { echo "$as_me:$LINENO: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&5 +echo "$as_me: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the compiler's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the compiler's result" >&2;} + ac_header_preproc=yes + ;; + no:yes:* ) + { echo "$as_me:$LINENO: WARNING: $ac_header: present but cannot be compiled" >&5 +echo "$as_me: WARNING: $ac_header: present but cannot be compiled" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: check for missing prerequisite headers?" >&5 +echo "$as_me: WARNING: $ac_header: check for missing prerequisite headers?" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: see the Autoconf documentation" >&5 +echo "$as_me: WARNING: $ac_header: see the Autoconf documentation" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&5 +echo "$as_me: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the preprocessor's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the preprocessor's result" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: in the future, the compiler will take precedence" >&5 +echo "$as_me: WARNING: $ac_header: in the future, the compiler will take precedence" >&2;} + ( + cat <<\_ASBOX +@%:@@%:@ ------------------------------------------ @%:@@%:@ +@%:@@%:@ Report this to the AC_PACKAGE_NAME lists. @%:@@%:@ +@%:@@%:@ ------------------------------------------ @%:@@%:@ +_ASBOX + ) | + sed "s/^/$as_me: WARNING: /" >&2 + ;; +esac +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + eval "$as_ac_Header=\$ac_header_preproc" +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 + +fi +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +@%:@define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + + +# +# finally create makefiles using Makefile.in +# +echo + ac_config_files="$ac_config_files Makefile demo/Makefile g2_perl/Makefile.PL" +cat >confcache <<\_ACEOF +# This file is a shell script that caches the results of configure +# tests run on this system so they can be shared between configure +# scripts and configure runs, see configure's option --config-cache. +# It is not useful on other systems. If it contains results you don't +# want to keep, you may remove or edit it. +# +# config.status only pays attention to the cache file if you give it +# the --recheck option to rerun configure. +# +# `ac_cv_env_foo' variables (set or unset) will be overridden when +# loading this file, other *unset* `ac_cv_foo' will be assigned the +# following values. + +_ACEOF + +# The following way of writing the cache mishandles newlines in values, +# but we know of no workaround that is simple, portable, and efficient. +# So, don't put newlines in cache variables' values. +# Ultrix sh set writes to stderr and can't be redirected directly, +# and sets the high bit in the cache file unless we assign to the vars. +{ + (set) 2>&1 | + case `(ac_space=' '; set | grep ac_space) 2>&1` in + *ac_space=\ *) + # `set' does not quote correctly, so add quotes (double-quote + # substitution turns \\\\ into \\, and sed turns \\ into \). + sed -n \ + "s/'/'\\\\''/g; + s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='\\2'/p" + ;; + *) + # `set' quotes correctly as required by POSIX, so do not add quotes. + sed -n \ + "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p" + ;; + esac; +} | + sed ' + t clear + : clear + s/^\([^=]*\)=\(.*[{}].*\)$/test "${\1+set}" = set || &/ + t end + /^ac_cv_env/!s/^\([^=]*\)=\(.*\)$/\1=${\1=\2}/ + : end' >>confcache +if diff $cache_file confcache >/dev/null 2>&1; then :; else + if test -w $cache_file; then + test "x$cache_file" != "x/dev/null" && echo "updating cache $cache_file" + cat confcache >$cache_file + else + echo "not updating unwritable cache $cache_file" + fi +fi +rm -f confcache + +test "x$prefix" = xNONE && prefix=$ac_default_prefix +# Let make expand exec_prefix. +test "x$exec_prefix" = xNONE && exec_prefix='${prefix}' + +# VPATH may cause trouble with some makes, so we remove $(srcdir), +# ${srcdir} and @srcdir@ from VPATH if srcdir is ".", strip leading and +# trailing colons and then remove the whole line if VPATH becomes empty +# (actually we leave an empty line to preserve line numbers). +if test "x$srcdir" = x.; then + ac_vpsub='/^[ ]*VPATH[ ]*=/{ +s/:*\$(srcdir):*/:/; +s/:*\${srcdir}:*/:/; +s/:*@srcdir@:*/:/; +s/^\([^=]*=[ ]*\):*/\1/; +s/:*$//; +s/^[^=]*=[ ]*$//; +}' +fi + +# Transform confdefs.h into DEFS. +# Protect against shell expansion while executing Makefile rules. +# Protect against Makefile macro expansion. +# +# If the first sed substitution is executed (which looks for macros that +# take arguments), then we branch to the quote section. Otherwise, +# look for a macro that doesn't take arguments. +cat >confdef2opt.sed <<\_ACEOF +t clear +: clear +s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*([^)]*)\)[ ]*\(.*\),-D\1=\2,g +t quote +s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\),-D\1=\2,g +t quote +d +: quote +s,[ `~#$^&*(){}\\|;'"<>?],\\&,g +s,\[,\\&,g +s,\],\\&,g +s,\$,$$,g +p +_ACEOF +# We use echo to avoid assuming a particular line-breaking character. +# The extra dot is to prevent the shell from consuming trailing +# line-breaks from the sub-command output. A line-break within +# single-quotes doesn't work because, if this script is created in a +# platform that uses two characters for line-breaks (e.g., DOS), tr +# would break. +ac_LF_and_DOT=`echo; echo .` +DEFS=`sed -n -f confdef2opt.sed confdefs.h | tr "$ac_LF_and_DOT" ' .'` +rm -f confdef2opt.sed + + +ac_libobjs= +ac_ltlibobjs= +for ac_i in : $LIB@&t@OBJS; do test "x$ac_i" = x: && continue + # 1. Remove the extension, and $U if already installed. + ac_i=`echo "$ac_i" | + sed 's/\$U\././;s/\.o$//;s/\.obj$//'` + # 2. Add them. + ac_libobjs="$ac_libobjs $ac_i\$U.$ac_objext" + ac_ltlibobjs="$ac_ltlibobjs $ac_i"'$U.lo' +done +LIB@&t@OBJS=$ac_libobjs + +LTLIBOBJS=$ac_ltlibobjs + + + +: ${CONFIG_STATUS=./config.status} +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files $CONFIG_STATUS" +{ echo "$as_me:$LINENO: creating $CONFIG_STATUS" >&5 +echo "$as_me: creating $CONFIG_STATUS" >&6;} +cat >$CONFIG_STATUS <<_ACEOF +#! $SHELL +# Generated by $as_me. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=\${CONFIG_SHELL-$SHELL} +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. 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The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. 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Logging --version etc. is OK. +exec 5>>config.log +{ + echo + sed 'h;s/./-/g;s/^.../@%:@@%:@ /;s/...$/ @%:@@%:@/;p;x;p;x' <<_ASBOX +@%:@@%:@ Running $as_me. @%:@@%:@ +_ASBOX +} >&5 +cat >&5 <<_CSEOF + +This file was extended by $as_me, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +_ACEOF + +# Files that config.status was made for. +if test -n "$ac_config_files"; then + echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_headers"; then + echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_links"; then + echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_commands"; then + echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS +fi + +cat >>$CONFIG_STATUS <<\_ACEOF + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + +Configuration files: +$config_files + +Report bugs to ." +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF +ac_cs_version="\\ +config.status +configured by $0, generated by GNU Autoconf 2.59, + with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=$srcdir +INSTALL="$INSTALL" +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +# If no file are specified by the user, then we need to provide default +# value. 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Set only those that are not. +# We use the long form for the default assignment because of an extremely +# bizarre bug on SunOS 4.1.3. +if $ac_need_defaults; then + test "${CONFIG_FILES+set}" = set || CONFIG_FILES=$config_files +fi + +# Have a temporary directory for convenience. Make it in the build tree +# simply because there is no reason to put it here, and in addition, +# creating and moving files from /tmp can sometimes cause problems. +# Create a temporary directory, and hook for its removal unless debugging. +$debug || +{ + trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0 + trap '{ (exit 1); exit 1; }' 1 2 13 15 +} + +# Create a (secure) tmp directory for tmp files. + +{ + tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` && + test -n "$tmp" && test -d "$tmp" +} || +{ + tmp=./confstat$$-$RANDOM + (umask 077 && mkdir $tmp) +} || +{ + echo "$me: cannot create a temporary directory in ." >&2 + { (exit 1); exit 1; } +} + +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF + +# +# CONFIG_FILES section. +# + +# No need to generate the scripts if there are no CONFIG_FILES. +# This happens for instance when ./config.status config.h +if test -n "\$CONFIG_FILES"; then + # Protect against being on the right side of a sed subst in config.status. + sed 's/,@/@@/; s/@,/@@/; s/,;t t\$/@;t t/; /@;t t\$/s/[\\\\&,]/\\\\&/g; + s/@@/,@/; s/@@/@,/; s/@;t t\$/,;t t/' >\$tmp/subs.sed <<\\CEOF +s,@SHELL@,$SHELL,;t t +s,@PATH_SEPARATOR@,$PATH_SEPARATOR,;t t +s,@PACKAGE_NAME@,$PACKAGE_NAME,;t t +s,@PACKAGE_TARNAME@,$PACKAGE_TARNAME,;t t +s,@PACKAGE_VERSION@,$PACKAGE_VERSION,;t t +s,@PACKAGE_STRING@,$PACKAGE_STRING,;t t +s,@PACKAGE_BUGREPORT@,$PACKAGE_BUGREPORT,;t t +s,@exec_prefix@,$exec_prefix,;t t +s,@prefix@,$prefix,;t t +s,@program_transform_name@,$program_transform_name,;t t +s,@bindir@,$bindir,;t t +s,@sbindir@,$sbindir,;t t +s,@libexecdir@,$libexecdir,;t t +s,@datadir@,$datadir,;t t +s,@sysconfdir@,$sysconfdir,;t t +s,@sharedstatedir@,$sharedstatedir,;t t +s,@localstatedir@,$localstatedir,;t t +s,@libdir@,$libdir,;t t +s,@includedir@,$includedir,;t t +s,@oldincludedir@,$oldincludedir,;t t +s,@infodir@,$infodir,;t t +s,@mandir@,$mandir,;t t +s,@build_alias@,$build_alias,;t t +s,@host_alias@,$host_alias,;t t +s,@target_alias@,$target_alias,;t t +s,@DEFS@,$DEFS,;t t +s,@ECHO_C@,$ECHO_C,;t t +s,@ECHO_N@,$ECHO_N,;t t +s,@ECHO_T@,$ECHO_T,;t t +s,@LIBS@,$LIBS,;t t +s,@build@,$build,;t t +s,@build_cpu@,$build_cpu,;t t +s,@build_vendor@,$build_vendor,;t t +s,@build_os@,$build_os,;t t +s,@host@,$host,;t t +s,@host_cpu@,$host_cpu,;t t +s,@host_vendor@,$host_vendor,;t t +s,@host_os@,$host_os,;t t +s,@LD_SHARED@,$LD_SHARED,;t t +s,@LD_SHARED_FLAGS@,$LD_SHARED_FLAGS,;t t +s,@LD_SHARED_OPT@,$LD_SHARED_OPT,;t t +s,@LD_SHARED_EXT@,$LD_SHARED_EXT,;t t +s,@CC@,$CC,;t t +s,@CFLAGS@,$CFLAGS,;t t +s,@LDFLAGS@,$LDFLAGS,;t t +s,@CPPFLAGS@,$CPPFLAGS,;t t +s,@ac_ct_CC@,$ac_ct_CC,;t t +s,@EXEEXT@,$EXEEXT,;t t +s,@OBJEXT@,$OBJEXT,;t t +s,@CPP@,$CPP,;t t +s,@CXX@,$CXX,;t t +s,@CXXFLAGS@,$CXXFLAGS,;t t +s,@ac_ct_CXX@,$ac_ct_CXX,;t t +s,@RANLIB@,$RANLIB,;t t +s,@ac_ct_RANLIB@,$ac_ct_RANLIB,;t t +s,@INSTALL_PROGRAM@,$INSTALL_PROGRAM,;t t +s,@INSTALL_SCRIPT@,$INSTALL_SCRIPT,;t t +s,@INSTALL_DATA@,$INSTALL_DATA,;t t +s,@FIND@,$FIND,;t t +s,@MAKEDEPEND@,$MAKEDEPEND,;t t +s,@X_CFLAGS@,$X_CFLAGS,;t t +s,@X_PRE_LIBS@,$X_PRE_LIBS,;t t +s,@X_LIBS@,$X_LIBS,;t t +s,@X_EXTRA_LIBS@,$X_EXTRA_LIBS,;t t +s,@DO_PS@,$DO_PS,;t t +s,@DO_FIG@,$DO_FIG,;t t +s,@DO_X11@,$DO_X11,;t t +s,@DO_WIN32@,$DO_WIN32,;t t +s,@DO_GD@,$DO_GD,;t t +s,@EGREP@,$EGREP,;t t +s,@LIB@&t@OBJS@,$LIB@&t@OBJS,;t t +s,@LTLIBOBJS@,$LTLIBOBJS,;t t +CEOF + +_ACEOF + + cat >>$CONFIG_STATUS <<\_ACEOF + # Split the substitutions into bite-sized pieces for seds with + # small command number limits, like on Digital OSF/1 and HP-UX. + ac_max_sed_lines=48 + ac_sed_frag=1 # Number of current file. + ac_beg=1 # First line for current file. + ac_end=$ac_max_sed_lines # Line after last line for current file. + ac_more_lines=: + ac_sed_cmds= + while $ac_more_lines; do + if test $ac_beg -gt 1; then + sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + else + sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + fi + if test ! 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Generated by config.status. */ + if test x"$ac_file" = x-; then + configure_input= + else + configure_input="$ac_file. 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So we exec the FD to /dev/null, +# effectively closing config.log, so it can be properly (re)opened and +# appended to by config.status. When coming back to configure, we +# need to make the FD available again. +if test "$no_create" != yes; then + ac_cs_success=: + ac_config_status_args= + test "$silent" = yes && + ac_config_status_args="$ac_config_status_args --quiet" + exec 5>/dev/null + $SHELL $CONFIG_STATUS $ac_config_status_args || ac_cs_success=false + exec 5>>config.log + # Use ||, not &&, to avoid exiting from the if with $? = 1, which + # would make configure fail if this is the last instruction. + $ac_cs_success || { (exit 1); exit 1; } +fi + + +echo +echo "Supported devices:" +if test "$DO_PS" != "#"; then echo " PostScript"; fi +if test "$DO_FIG" != "#"; then echo " FIG"; fi +if test "$DO_X11" != "#"; then echo " X11"; fi +if test "$DO_WIN32" != "#"; then echo " Win32"; fi +if test "$DO_GD" != "#"; then echo " GD"; fi + +echo +echo "Unsupported devices:" +if test "$DO_PS" = "#"; then echo " PostScript"; fi +if test "$DO_FIG" = "#"; then echo " FIG"; fi +if test "$DO_X11" = "#"; then echo " X11"; fi +if test "$DO_WIN32" = "#"; then echo " Win32"; fi +if test "$DO_GD" = "#"; then echo " GD"; fi + +echo +echo "Run 'make depend' to create dependencies." +echo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/requests b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/requests new file mode 100755 index 00000000..a9ac0c3d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/requests @@ -0,0 +1,123 @@ +# This file was generated. +# It contains the lists of macros which have been traced. +# It can be safely removed. + +@request = ( + bless( [ + '0', + 1, + [ + '/usr/share/autoconf' + ], + [ + '/usr/share/autoconf/autoconf/autoconf.m4f', + 'configure.in' + ], + { + '_LT_AC_TAGCONFIG' => 1, + 'm4_pattern_forbid' => 1, + 'AC_CANONICAL_TARGET' => 1, + 'AC_CONFIG_LIBOBJ_DIR' => 1, + 'AC_C_VOLATILE' => 1, + 'AC_TYPE_OFF_T' => 1, + 'AC_FUNC_CLOSEDIR_VOID' => 1, + 'AC_REPLACE_FNMATCH' => 1, + 'AC_DEFUN' => 1, + 'AC_PROG_LIBTOOL' => 1, + 'AC_FUNC_STAT' => 1, + 'AC_FUNC_WAIT3' => 1, + 'AC_HEADER_TIME' => 1, + 'AC_FUNC_LSTAT' => 1, + 'AC_STRUCT_TM' => 1, + 'AM_AUTOMAKE_VERSION' => 1, + 'AC_FUNC_GETMNTENT' => 1, + 'AC_TYPE_MODE_T' => 1, + 'AC_CHECK_HEADERS' => 1, + 'AC_FUNC_STRTOD' => 1, + 'AC_FUNC_STRNLEN' => 1, + 'm4_sinclude' => 1, + 'AC_PROG_CXX' => 1, + 'AC_PATH_X' => 1, + 'AC_FUNC_LSTAT_FOLLOWS_SLASHED_SYMLINK' => 1, + 'AC_PROG_AWK' => 1, + '_m4_warn' => 1, + 'AC_HEADER_STDC' => 1, + 'AC_HEADER_MAJOR' => 1, + 'AC_FUNC_ERROR_AT_LINE' => 1, + 'AC_PROG_GCC_TRADITIONAL' => 1, + 'AC_LIBSOURCE' => 1, + 'AC_FUNC_MBRTOWC' => 1, + 'AC_STRUCT_ST_BLOCKS' => 1, + 'AC_CANONICAL_BUILD' => 1, + 'AC_TYPE_SIGNAL' => 1, + 'AC_TYPE_UID_T' => 1, + 'AC_PROG_MAKE_SET' => 1, + 'AC_CONFIG_AUX_DIR' => 1, + 'm4_pattern_allow' => 1, + 'sinclude' => 1, + 'AC_DEFINE_TRACE_LITERAL' => 1, + 'AC_FUNC_STRERROR_R' => 1, + 'AC_PROG_CC' => 1, + 'AC_FUNC_FORK' => 1, + 'AC_DECL_SYS_SIGLIST' => 1, + 'AU_DEFUN' => 1, + 'AC_FUNC_STRCOLL' => 1, + 'AC_FUNC_VPRINTF' => 1, + 'AC_PROG_YACC' => 1, + 'AC_INIT' => 1, + 'AC_STRUCT_TIMEZONE' => 1, + 'AC_FUNC_CHOWN' => 1, + 'AC_SUBST' => 1, + 'AC_FUNC_ALLOCA' => 1, + 'AC_CANONICAL_HOST' => 1, + 'AC_FUNC_GETPGRP' => 1, + 'AC_PROG_RANLIB' => 1, + 'AM_INIT_AUTOMAKE' => 1, + 'AC_FUNC_SETPGRP' => 1, + 'AC_CONFIG_SUBDIRS' => 1, + 'AC_FUNC_MMAP' => 1, + 'AC_FUNC_REALLOC' => 1, + 'AC_TYPE_SIZE_T' => 1, + 'AC_CONFIG_LINKS' => 1, + 'AC_CHECK_TYPES' => 1, + 'LT_SUPPORTED_TAG' => 1, + 'AC_CHECK_MEMBERS' => 1, + 'AM_MAINTAINER_MODE' => 1, + 'AC_DEFUN_ONCE' => 1, + 'AC_FUNC_UTIME_NULL' => 1, + 'AC_FUNC_SELECT_ARGTYPES' => 1, + 'AC_HEADER_STAT' => 1, + 'AC_FUNC_STRFTIME' => 1, + 'AC_PROG_CPP' => 1, + 'AC_C_INLINE' => 1, + 'AM_ENABLE_MULTILIB' => 1, + 'AC_PROG_LEX' => 1, + 'AC_C_CONST' => 1, + 'AC_TYPE_PID_T' => 1, + 'AC_CONFIG_FILES' => 1, + 'include' => 1, + 'AC_FUNC_SETVBUF_REVERSED' => 1, + 'AC_PROG_INSTALL' => 1, + 'AM_GNU_GETTEXT' => 1, + 'AC_FUNC_OBSTACK' => 1, + 'AC_CHECK_LIB' => 1, + 'AC_FUNC_MALLOC' => 1, + 'AC_FUNC_GETGROUPS' => 1, + 'AC_FUNC_GETLOADAVG' => 1, + 'AH_OUTPUT' => 1, + 'AC_FUNC_FSEEKO' => 1, + 'AM_PROG_CC_C_O' => 1, + 'AC_FUNC_MKTIME' => 1, + 'AC_CANONICAL_SYSTEM' => 1, + 'AM_CONDITIONAL' => 1, + 'AC_CONFIG_HEADERS' => 1, + 'AC_HEADER_SYS_WAIT' => 1, + 'AC_PROG_LN_S' => 1, + 'AC_FUNC_MEMCMP' => 1, + 'm4_include' => 1, + 'AC_HEADER_DIRENT' => 1, + 'AC_CHECK_FUNCS' => 1 + } + ], 'Autom4te::Request' ) + ); + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/traces.0 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/traces.0 new file mode 100755 index 00000000..6a5c04d1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/autom4te.cache/traces.0 @@ -0,0 +1,191 @@ +m4trace:configure.in:5: -1- 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AC_CHECK_LIB([gd], [main], [have_gd=yes], [have_gd=no]) +m4trace:configure.in:82: -2- AC_DEFINE_TRACE_LITERAL([DO_GD]) +m4trace:configure.in:88: -1- _m4_warn([obsolete], [The macro `AC_CYGWIN' is obsolete. +You should run autoupdate.], [autoconf/specific.m4:363: AC_CYGWIN is expanded from... +configure.in:88: the top level]) +m4trace:configure.in:88: -1- AC_CANONICAL_HOST +m4trace:configure.in:88: -1- _m4_warn([syntax], [AC_CANONICAL_HOST invoked multiple times], [autoconf/specific.m4:363: AC_CYGWIN is expanded from... +configure.in:88: the top level]) +m4trace:configure.in:88: -1- _m4_warn([obsolete], [AC_CYGWIN is obsolete: use AC_CANONICAL_HOST and $host_os], [autoconf/specific.m4:363: AC_CYGWIN is expanded from... +configure.in:88: the top level]) +m4trace:configure.in:92: -2- AC_DEFINE_TRACE_LITERAL([DO_WIN32]) +m4trace:configure.in:92: -1- AC_CHECK_LIB([gdi32], [main], [DO_WIN32='';LDFLAGS="$LDFLAGS -lgdi32";cat >>confdefs.h <<\_ACEOF +@%:@define DO_WIN32 1 +_ACEOF +]) +m4trace:configure.in:93: -1- AC_CHECK_LIB([bgd], [main], [have_bgd=yes], [have_bgd=no]) +m4trace:configure.in:97: -2- AC_DEFINE_TRACE_LITERAL([DO_GD]) +m4trace:configure.in:104: -1- AC_SUBST([DO_PS]) +m4trace:configure.in:105: -1- AC_SUBST([DO_FIG]) +m4trace:configure.in:106: -1- AC_SUBST([DO_X11]) +m4trace:configure.in:107: -1- AC_SUBST([DO_WIN32]) +m4trace:configure.in:108: -1- AC_SUBST([DO_GD]) +m4trace:configure.in:110: -1- AC_HEADER_STDC +m4trace:configure.in:110: -1- AC_SUBST([EGREP]) +m4trace:configure.in:110: -1- AC_DEFINE_TRACE_LITERAL([STDC_HEADERS]) +m4trace:configure.in:110: -1- AH_OUTPUT([STDC_HEADERS], [/* Define to 1 if you have the ANSI C header files. */ +#undef STDC_HEADERS]) +m4trace:configure.in:111: -1- AC_CHECK_HEADERS([limits.h]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_LIMITS_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_LIMITS_H]) +m4trace:configure.in:111: -1- AC_CHECK_HEADERS([sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h], [], [], [$ac_includes_default]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_SYS_TYPES_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_TYPES_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_SYS_STAT_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_STAT_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_STDLIB_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_STDLIB_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_STRING_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_STRING_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_MEMORY_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_MEMORY_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_STRINGS_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_STRINGS_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_INTTYPES_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_INTTYPES_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_STDINT_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_STDINT_H]) +m4trace:configure.in:111: -1- AH_OUTPUT([HAVE_UNISTD_H], [/* Define to 1 if you have the header file. */ +#undef HAVE_UNISTD_H]) +m4trace:configure.in:119: -1- AC_CONFIG_FILES([Makefile demo/Makefile g2_perl/Makefile.PL]) +m4trace:configure.in:119: -1- _m4_warn([obsolete], [AC_OUTPUT should be used without arguments. +You should run autoupdate.], []) +m4trace:configure.in:119: -1- AC_SUBST([LIB@&t@OBJS], [$ac_libobjs]) +m4trace:configure.in:119: -1- AC_SUBST([LTLIBOBJS], [$ac_ltlibobjs]) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.guess b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.guess new file mode 100755 index 00000000..6be7a693 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.guess @@ -0,0 +1,1450 @@ +#! /bin/sh +# Attempt to guess a canonical system name. +# Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, +# 2000, 2001, 2002, 2003, 2004 Free Software Foundation, Inc. + +timestamp='2004-08-11' + +# This file is free software; you can redistribute it and/or modify it +# under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2 of the License, or +# (at your option) any later version. +# +# This program is distributed in the hope that it will be useful, but +# WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +# General Public License for more details. +# +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA. +# +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Originally written by Per Bothner . +# Please send patches to . Submit a context +# diff and a properly formatted ChangeLog entry. +# +# This script attempts to guess a canonical system name similar to +# config.sub. If it succeeds, it prints the system name on stdout, and +# exits with 0. Otherwise, it exits with 1. +# +# The plan is that this can be called by configure scripts if you +# don't specify an explicit build system type. + +me=`echo "$0" | sed -e 's,.*/,,'` + +usage="\ +Usage: $0 [OPTION] + +Output the configuration name of the system \`$me' is run on. + +Operation modes: + -h, --help print this help, then exit + -t, --time-stamp print date of last modification, then exit + -v, --version print version number, then exit + +Report bugs and patches to ." + +version="\ +GNU config.guess ($timestamp) + +Originally written by Per Bothner. +Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004 +Free Software Foundation, Inc. + +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE." + +help=" +Try \`$me --help' for more information." + +# Parse command line +while test $# -gt 0 ; do + case $1 in + --time-stamp | --time* | -t ) + echo "$timestamp" ; exit 0 ;; + --version | -v ) + echo "$version" ; exit 0 ;; + --help | --h* | -h ) + echo "$usage"; exit 0 ;; + -- ) # Stop option processing + shift; break ;; + - ) # Use stdin as input. + break ;; + -* ) + echo "$me: invalid option $1$help" >&2 + exit 1 ;; + * ) + break ;; + esac +done + +if test $# != 0; then + echo "$me: too many arguments$help" >&2 + exit 1 +fi + +trap 'exit 1' 1 2 15 + +# CC_FOR_BUILD -- compiler used by this script. Note that the use of a +# compiler to aid in system detection is discouraged as it requires +# temporary files to be created and, as you can see below, it is a +# headache to deal with in a portable fashion. + +# Historically, `CC_FOR_BUILD' used to be named `HOST_CC'. We still +# use `HOST_CC' if defined, but it is deprecated. + +# Portable tmp directory creation inspired by the Autoconf team. + +set_cc_for_build=' +trap "exitcode=\$?; (rm -f \$tmpfiles 2>/dev/null; rmdir \$tmp 2>/dev/null) && exit \$exitcode" 0 ; +trap "rm -f \$tmpfiles 2>/dev/null; rmdir \$tmp 2>/dev/null; exit 1" 1 2 13 15 ; +: ${TMPDIR=/tmp} ; + { tmp=`(umask 077 && mktemp -d -q "$TMPDIR/cgXXXXXX") 2>/dev/null` && test -n "$tmp" && test -d "$tmp" ; } || + { test -n "$RANDOM" && tmp=$TMPDIR/cg$$-$RANDOM && (umask 077 && mkdir $tmp) ; } || + { tmp=$TMPDIR/cg-$$ && (umask 077 && mkdir $tmp) && echo "Warning: creating insecure temp directory" >&2 ; } || + { echo "$me: cannot create a temporary directory in $TMPDIR" >&2 ; exit 1 ; } ; +dummy=$tmp/dummy ; +tmpfiles="$dummy.c $dummy.o $dummy.rel $dummy" ; +case $CC_FOR_BUILD,$HOST_CC,$CC in + ,,) echo "int x;" > $dummy.c ; + for c in cc gcc c89 c99 ; do + if ($c -c -o $dummy.o $dummy.c) >/dev/null 2>&1 ; then + CC_FOR_BUILD="$c"; break ; + fi ; + done ; + if test x"$CC_FOR_BUILD" = x ; then + CC_FOR_BUILD=no_compiler_found ; + fi + ;; + ,,*) CC_FOR_BUILD=$CC ;; + ,*,*) CC_FOR_BUILD=$HOST_CC ;; +esac ;' + +# This is needed to find uname on a Pyramid OSx when run in the BSD universe. +# (ghazi@noc.rutgers.edu 1994-08-24) +if (test -f /.attbin/uname) >/dev/null 2>&1 ; then + PATH=$PATH:/.attbin ; export PATH +fi + +UNAME_MACHINE=`(uname -m) 2>/dev/null` || UNAME_MACHINE=unknown +UNAME_RELEASE=`(uname -r) 2>/dev/null` || UNAME_RELEASE=unknown +UNAME_SYSTEM=`(uname -s) 2>/dev/null` || UNAME_SYSTEM=unknown +UNAME_VERSION=`(uname -v) 2>/dev/null` || UNAME_VERSION=unknown + +# Note: order is significant - the case branches are not exclusive. + +case "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" in + *:NetBSD:*:*) + # NetBSD (nbsd) targets should (where applicable) match one or + # more of the tupples: *-*-netbsdelf*, *-*-netbsdaout*, + # *-*-netbsdecoff* and *-*-netbsd*. For targets that recently + # switched to ELF, *-*-netbsd* would select the old + # object file format. This provides both forward + # compatibility and a consistent mechanism for selecting the + # object file format. + # + # Note: NetBSD doesn't particularly care about the vendor + # portion of the name. We always set it to "unknown". + sysctl="sysctl -n hw.machine_arch" + UNAME_MACHINE_ARCH=`(/sbin/$sysctl 2>/dev/null || \ + /usr/sbin/$sysctl 2>/dev/null || echo unknown)` + case "${UNAME_MACHINE_ARCH}" in + armeb) machine=armeb-unknown ;; + arm*) machine=arm-unknown ;; + sh3el) machine=shl-unknown ;; + sh3eb) machine=sh-unknown ;; + *) machine=${UNAME_MACHINE_ARCH}-unknown ;; + esac + # The Operating System including object format, if it has switched + # to ELF recently, or will in the future. + case "${UNAME_MACHINE_ARCH}" in + arm*|i386|m68k|ns32k|sh3*|sparc|vax) + eval $set_cc_for_build + if echo __ELF__ | $CC_FOR_BUILD -E - 2>/dev/null \ + | grep __ELF__ >/dev/null + then + # Once all utilities can be ECOFF (netbsdecoff) or a.out (netbsdaout). + # Return netbsd for either. FIX? + os=netbsd + else + os=netbsdelf + fi + ;; + *) + os=netbsd + ;; + esac + # The OS release + # Debian GNU/NetBSD machines have a different userland, and + # thus, need a distinct triplet. However, they do not need + # kernel version information, so it can be replaced with a + # suitable tag, in the style of linux-gnu. + case "${UNAME_VERSION}" in + Debian*) + release='-gnu' + ;; + *) + release=`echo ${UNAME_RELEASE}|sed -e 's/[-_].*/\./'` + ;; + esac + # Since CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM: + # contains redundant information, the shorter form: + # CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM is used. + echo "${machine}-${os}${release}" + exit 0 ;; + amd64:OpenBSD:*:*) + echo x86_64-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + amiga:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + arc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + cats:OpenBSD:*:*) + echo arm-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + hp300:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + luna88k:OpenBSD:*:*) + echo m88k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mac68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + macppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme88k:OpenBSD:*:*) + echo m88k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvmeppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + pmax:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sgi:OpenBSD:*:*) + echo mipseb-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sun3:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + wgrisc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + *:OpenBSD:*:*) + echo ${UNAME_MACHINE}-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + *:ekkoBSD:*:*) + echo ${UNAME_MACHINE}-unknown-ekkobsd${UNAME_RELEASE} + exit 0 ;; + macppc:MirBSD:*:*) + echo powerppc-unknown-mirbsd${UNAME_RELEASE} + exit 0 ;; + *:MirBSD:*:*) + echo ${UNAME_MACHINE}-unknown-mirbsd${UNAME_RELEASE} + exit 0 ;; + alpha:OSF1:*:*) + case $UNAME_RELEASE in + *4.0) + UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $3}'` + ;; + *5.*) + UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $4}'` + ;; + esac + # According to Compaq, /usr/sbin/psrinfo has been available on + # OSF/1 and Tru64 systems produced since 1995. I hope that + # covers most systems running today. This code pipes the CPU + # types through head -n 1, so we only detect the type of CPU 0. + ALPHA_CPU_TYPE=`/usr/sbin/psrinfo -v | sed -n -e 's/^ The alpha \(.*\) processor.*$/\1/p' | head -n 1` + case "$ALPHA_CPU_TYPE" in + "EV4 (21064)") + UNAME_MACHINE="alpha" ;; + "EV4.5 (21064)") + UNAME_MACHINE="alpha" ;; + "LCA4 (21066/21068)") + UNAME_MACHINE="alpha" ;; + "EV5 (21164)") + UNAME_MACHINE="alphaev5" ;; + "EV5.6 (21164A)") + UNAME_MACHINE="alphaev56" ;; + "EV5.6 (21164PC)") + UNAME_MACHINE="alphapca56" ;; + "EV5.7 (21164PC)") + UNAME_MACHINE="alphapca57" ;; + "EV6 (21264)") + UNAME_MACHINE="alphaev6" ;; + "EV6.7 (21264A)") + UNAME_MACHINE="alphaev67" ;; + "EV6.8CB (21264C)") + UNAME_MACHINE="alphaev68" ;; + "EV6.8AL (21264B)") + UNAME_MACHINE="alphaev68" ;; + "EV6.8CX (21264D)") + UNAME_MACHINE="alphaev68" ;; + "EV6.9A (21264/EV69A)") + UNAME_MACHINE="alphaev69" ;; + "EV7 (21364)") + UNAME_MACHINE="alphaev7" ;; + "EV7.9 (21364A)") + UNAME_MACHINE="alphaev79" ;; + esac + # A Pn.n version is a patched version. + # A Vn.n version is a released version. + # A Tn.n version is a released field test version. + # A Xn.n version is an unreleased experimental baselevel. + # 1.2 uses "1.2" for uname -r. + echo ${UNAME_MACHINE}-dec-osf`echo ${UNAME_RELEASE} | sed -e 's/^[PVTX]//' | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + exit 0 ;; + Alpha\ *:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # Should we change UNAME_MACHINE based on the output of uname instead + # of the specific Alpha model? + echo alpha-pc-interix + exit 0 ;; + 21064:Windows_NT:50:3) + echo alpha-dec-winnt3.5 + exit 0 ;; + Amiga*:UNIX_System_V:4.0:*) + echo m68k-unknown-sysv4 + exit 0;; + *:[Aa]miga[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-amigaos + exit 0 ;; + *:[Mm]orph[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-morphos + exit 0 ;; + *:OS/390:*:*) + echo i370-ibm-openedition + exit 0 ;; + *:OS400:*:*) + echo powerpc-ibm-os400 + exit 0 ;; + arm:RISC*:1.[012]*:*|arm:riscix:1.[012]*:*) + echo arm-acorn-riscix${UNAME_RELEASE} + exit 0;; + SR2?01:HI-UX/MPP:*:* | SR8000:HI-UX/MPP:*:*) + echo hppa1.1-hitachi-hiuxmpp + exit 0;; + Pyramid*:OSx*:*:* | MIS*:OSx*:*:* | MIS*:SMP_DC-OSx*:*:*) + # akee@wpdis03.wpafb.af.mil (Earle F. Ake) contributed MIS and NILE. + if test "`(/bin/universe) 2>/dev/null`" = att ; then + echo pyramid-pyramid-sysv3 + else + echo pyramid-pyramid-bsd + fi + exit 0 ;; + NILE*:*:*:dcosx) + echo pyramid-pyramid-svr4 + exit 0 ;; + DRS?6000:unix:4.0:6*) + echo sparc-icl-nx6 + exit 0 ;; + DRS?6000:UNIX_SV:4.2*:7*) + case `/usr/bin/uname -p` in + sparc) echo sparc-icl-nx7 && exit 0 ;; + esac ;; + sun4H:SunOS:5.*:*) + echo sparc-hal-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:5.*:* | tadpole*:SunOS:5.*:*) + echo sparc-sun-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + i86pc:SunOS:5.*:*) + echo i386-pc-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:6*:*) + # According to config.sub, this is the proper way to canonicalize + # SunOS6. Hard to guess exactly what SunOS6 will be like, but + # it's likely to be more like Solaris than SunOS4. + echo sparc-sun-solaris3`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:*:*) + case "`/usr/bin/arch -k`" in + Series*|S4*) + UNAME_RELEASE=`uname -v` + ;; + esac + # Japanese Language versions have a version number like `4.1.3-JL'. + echo sparc-sun-sunos`echo ${UNAME_RELEASE}|sed -e 's/-/_/'` + exit 0 ;; + sun3*:SunOS:*:*) + echo m68k-sun-sunos${UNAME_RELEASE} + exit 0 ;; + sun*:*:4.2BSD:*) + UNAME_RELEASE=`(sed 1q /etc/motd | awk '{print substr($5,1,3)}') 2>/dev/null` + test "x${UNAME_RELEASE}" = "x" && UNAME_RELEASE=3 + case "`/bin/arch`" in + sun3) + echo m68k-sun-sunos${UNAME_RELEASE} + ;; + sun4) + echo sparc-sun-sunos${UNAME_RELEASE} + ;; + esac + exit 0 ;; + aushp:SunOS:*:*) + echo sparc-auspex-sunos${UNAME_RELEASE} + exit 0 ;; + # The situation for MiNT is a little confusing. The machine name + # can be virtually everything (everything which is not + # "atarist" or "atariste" at least should have a processor + # > m68000). The system name ranges from "MiNT" over "FreeMiNT" + # to the lowercase version "mint" (or "freemint"). Finally + # the system name "TOS" denotes a system which is actually not + # MiNT. But MiNT is downward compatible to TOS, so this should + # be no problem. + atarist[e]:*MiNT:*:* | atarist[e]:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + atari*:*MiNT:*:* | atari*:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + *falcon*:*MiNT:*:* | *falcon*:*mint:*:* | *falcon*:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + milan*:*MiNT:*:* | milan*:*mint:*:* | *milan*:*TOS:*:*) + echo m68k-milan-mint${UNAME_RELEASE} + exit 0 ;; + hades*:*MiNT:*:* | hades*:*mint:*:* | *hades*:*TOS:*:*) + echo m68k-hades-mint${UNAME_RELEASE} + exit 0 ;; + *:*MiNT:*:* | *:*mint:*:* | *:*TOS:*:*) + echo m68k-unknown-mint${UNAME_RELEASE} + exit 0 ;; + m68k:machten:*:*) + echo m68k-apple-machten${UNAME_RELEASE} + exit 0 ;; + powerpc:machten:*:*) + echo powerpc-apple-machten${UNAME_RELEASE} + exit 0 ;; + RISC*:Mach:*:*) + echo mips-dec-mach_bsd4.3 + exit 0 ;; + RISC*:ULTRIX:*:*) + echo mips-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + VAX*:ULTRIX*:*:*) + echo vax-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + 2020:CLIX:*:* | 2430:CLIX:*:*) + echo clipper-intergraph-clix${UNAME_RELEASE} + exit 0 ;; + mips:*:*:UMIPS | mips:*:*:RISCos) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c +#ifdef __cplusplus +#include /* for printf() prototype */ + int main (int argc, char *argv[]) { +#else + int main (argc, argv) int argc; char *argv[]; { +#endif + #if defined (host_mips) && defined (MIPSEB) + #if defined (SYSTYPE_SYSV) + printf ("mips-mips-riscos%ssysv\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_SVR4) + printf ("mips-mips-riscos%ssvr4\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_BSD43) || defined(SYSTYPE_BSD) + printf ("mips-mips-riscos%sbsd\n", argv[1]); exit (0); + #endif + #endif + exit (-1); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c \ + && $dummy `echo "${UNAME_RELEASE}" | sed -n 's/\([0-9]*\).*/\1/p'` \ + && exit 0 + echo mips-mips-riscos${UNAME_RELEASE} + exit 0 ;; + Motorola:PowerMAX_OS:*:*) + echo powerpc-motorola-powermax + exit 0 ;; + Motorola:*:4.3:PL8-*) + echo powerpc-harris-powermax + exit 0 ;; + Night_Hawk:*:*:PowerMAX_OS | Synergy:PowerMAX_OS:*:*) + echo powerpc-harris-powermax + exit 0 ;; + Night_Hawk:Power_UNIX:*:*) + echo powerpc-harris-powerunix + exit 0 ;; + m88k:CX/UX:7*:*) + echo m88k-harris-cxux7 + exit 0 ;; + m88k:*:4*:R4*) + echo m88k-motorola-sysv4 + exit 0 ;; + m88k:*:3*:R3*) + echo m88k-motorola-sysv3 + exit 0 ;; + AViiON:dgux:*:*) + # DG/UX returns AViiON for all architectures + UNAME_PROCESSOR=`/usr/bin/uname -p` + if [ $UNAME_PROCESSOR = mc88100 ] || [ $UNAME_PROCESSOR = mc88110 ] + then + if [ ${TARGET_BINARY_INTERFACE}x = m88kdguxelfx ] || \ + [ ${TARGET_BINARY_INTERFACE}x = x ] + then + echo m88k-dg-dgux${UNAME_RELEASE} + else + echo m88k-dg-dguxbcs${UNAME_RELEASE} + fi + else + echo i586-dg-dgux${UNAME_RELEASE} + fi + exit 0 ;; + M88*:DolphinOS:*:*) # DolphinOS (SVR3) + echo m88k-dolphin-sysv3 + exit 0 ;; + M88*:*:R3*:*) + # Delta 88k system running SVR3 + echo m88k-motorola-sysv3 + exit 0 ;; + XD88*:*:*:*) # Tektronix XD88 system running UTekV (SVR3) + echo m88k-tektronix-sysv3 + exit 0 ;; + Tek43[0-9][0-9]:UTek:*:*) # Tektronix 4300 system running UTek (BSD) + echo m68k-tektronix-bsd + exit 0 ;; + *:IRIX*:*:*) + echo mips-sgi-irix`echo ${UNAME_RELEASE}|sed -e 's/-/_/g'` + exit 0 ;; + ????????:AIX?:[12].1:2) # AIX 2.2.1 or AIX 2.1.1 is RT/PC AIX. + echo romp-ibm-aix # uname -m gives an 8 hex-code CPU id + exit 0 ;; # Note that: echo "'`uname -s`'" gives 'AIX ' + i*86:AIX:*:*) + echo i386-ibm-aix + exit 0 ;; + ia64:AIX:*:*) + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${UNAME_MACHINE}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:2:3) + if grep bos325 /usr/include/stdio.h >/dev/null 2>&1; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + + main() + { + if (!__power_pc()) + exit(1); + puts("powerpc-ibm-aix3.2.5"); + exit(0); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c && $dummy && exit 0 + echo rs6000-ibm-aix3.2.5 + elif grep bos324 /usr/include/stdio.h >/dev/null 2>&1; then + echo rs6000-ibm-aix3.2.4 + else + echo rs6000-ibm-aix3.2 + fi + exit 0 ;; + *:AIX:*:[45]) + IBM_CPU_ID=`/usr/sbin/lsdev -C -c processor -S available | sed 1q | awk '{ print $1 }'` + if /usr/sbin/lsattr -El ${IBM_CPU_ID} | grep ' POWER' >/dev/null 2>&1; then + IBM_ARCH=rs6000 + else + IBM_ARCH=powerpc + fi + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${IBM_ARCH}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:*:*) + echo rs6000-ibm-aix + exit 0 ;; + ibmrt:4.4BSD:*|romp-ibm:BSD:*) + echo romp-ibm-bsd4.4 + exit 0 ;; + ibmrt:*BSD:*|romp-ibm:BSD:*) # covers RT/PC BSD and + echo romp-ibm-bsd${UNAME_RELEASE} # 4.3 with uname added to + exit 0 ;; # report: romp-ibm BSD 4.3 + *:BOSX:*:*) + echo rs6000-bull-bosx + exit 0 ;; + DPX/2?00:B.O.S.:*:*) + echo m68k-bull-sysv3 + exit 0 ;; + 9000/[34]??:4.3bsd:1.*:*) + echo m68k-hp-bsd + exit 0 ;; + hp300:4.4BSD:*:* | 9000/[34]??:4.3bsd:2.*:*) + echo m68k-hp-bsd4.4 + exit 0 ;; + 9000/[34678]??:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + case "${UNAME_MACHINE}" in + 9000/31? ) HP_ARCH=m68000 ;; + 9000/[34]?? ) HP_ARCH=m68k ;; + 9000/[678][0-9][0-9]) + if [ -x /usr/bin/getconf ]; then + sc_cpu_version=`/usr/bin/getconf SC_CPU_VERSION 2>/dev/null` + sc_kernel_bits=`/usr/bin/getconf SC_KERNEL_BITS 2>/dev/null` + case "${sc_cpu_version}" in + 523) HP_ARCH="hppa1.0" ;; # CPU_PA_RISC1_0 + 528) HP_ARCH="hppa1.1" ;; # CPU_PA_RISC1_1 + 532) # CPU_PA_RISC2_0 + case "${sc_kernel_bits}" in + 32) HP_ARCH="hppa2.0n" ;; + 64) HP_ARCH="hppa2.0w" ;; + '') HP_ARCH="hppa2.0" ;; # HP-UX 10.20 + esac ;; + esac + fi + if [ "${HP_ARCH}" = "" ]; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + + #define _HPUX_SOURCE + #include + #include + + int main () + { + #if defined(_SC_KERNEL_BITS) + long bits = sysconf(_SC_KERNEL_BITS); + #endif + long cpu = sysconf (_SC_CPU_VERSION); + + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1"); break; + case CPU_PA_RISC2_0: + #if defined(_SC_KERNEL_BITS) + switch (bits) + { + case 64: puts ("hppa2.0w"); break; + case 32: puts ("hppa2.0n"); break; + default: puts ("hppa2.0"); break; + } break; + #else /* !defined(_SC_KERNEL_BITS) */ + puts ("hppa2.0"); break; + #endif + default: puts ("hppa1.0"); break; + } + exit (0); + } +EOF + (CCOPTS= $CC_FOR_BUILD -o $dummy $dummy.c 2>/dev/null) && HP_ARCH=`$dummy` + test -z "$HP_ARCH" && HP_ARCH=hppa + fi ;; + esac + if [ ${HP_ARCH} = "hppa2.0w" ] + then + # avoid double evaluation of $set_cc_for_build + test -n "$CC_FOR_BUILD" || eval $set_cc_for_build + if echo __LP64__ | (CCOPTS= $CC_FOR_BUILD -E -) | grep __LP64__ >/dev/null + then + HP_ARCH="hppa2.0w" + else + HP_ARCH="hppa64" + fi + fi + echo ${HP_ARCH}-hp-hpux${HPUX_REV} + exit 0 ;; + ia64:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + echo ia64-hp-hpux${HPUX_REV} + exit 0 ;; + 3050*:HI-UX:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + int + main () + { + long cpu = sysconf (_SC_CPU_VERSION); + /* The order matters, because CPU_IS_HP_MC68K erroneously returns + true for CPU_PA_RISC1_0. CPU_IS_PA_RISC returns correct + results, however. */ + if (CPU_IS_PA_RISC (cpu)) + { + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0-hitachi-hiuxwe2"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1-hitachi-hiuxwe2"); break; + case CPU_PA_RISC2_0: puts ("hppa2.0-hitachi-hiuxwe2"); break; + default: puts ("hppa-hitachi-hiuxwe2"); break; + } + } + else if (CPU_IS_HP_MC68K (cpu)) + puts ("m68k-hitachi-hiuxwe2"); + else puts ("unknown-hitachi-hiuxwe2"); + exit (0); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c && $dummy && exit 0 + echo unknown-hitachi-hiuxwe2 + exit 0 ;; + 9000/7??:4.3bsd:*:* | 9000/8?[79]:4.3bsd:*:* ) + echo hppa1.1-hp-bsd + exit 0 ;; + 9000/8??:4.3bsd:*:*) + echo hppa1.0-hp-bsd + exit 0 ;; + *9??*:MPE/iX:*:* | *3000*:MPE/iX:*:*) + echo hppa1.0-hp-mpeix + exit 0 ;; + hp7??:OSF1:*:* | hp8?[79]:OSF1:*:* ) + echo hppa1.1-hp-osf + exit 0 ;; + hp8??:OSF1:*:*) + echo hppa1.0-hp-osf + exit 0 ;; + i*86:OSF1:*:*) + if [ -x /usr/sbin/sysversion ] ; then + echo ${UNAME_MACHINE}-unknown-osf1mk + else + echo ${UNAME_MACHINE}-unknown-osf1 + fi + exit 0 ;; + parisc*:Lites*:*:*) + echo hppa1.1-hp-lites + exit 0 ;; + C1*:ConvexOS:*:* | convex:ConvexOS:C1*:*) + echo c1-convex-bsd + exit 0 ;; + C2*:ConvexOS:*:* | convex:ConvexOS:C2*:*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + C34*:ConvexOS:*:* | convex:ConvexOS:C34*:*) + echo c34-convex-bsd + exit 0 ;; + C38*:ConvexOS:*:* | convex:ConvexOS:C38*:*) + echo c38-convex-bsd + exit 0 ;; + C4*:ConvexOS:*:* | convex:ConvexOS:C4*:*) + echo c4-convex-bsd + exit 0 ;; + CRAY*Y-MP:*:*:*) + echo ymp-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*[A-Z]90:*:*:*) + echo ${UNAME_MACHINE}-cray-unicos${UNAME_RELEASE} \ + | sed -e 's/CRAY.*\([A-Z]90\)/\1/' \ + -e y/ABCDEFGHIJKLMNOPQRSTUVWXYZ/abcdefghijklmnopqrstuvwxyz/ \ + -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*TS:*:*:*) + echo t90-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*T3E:*:*:*) + echo alphaev5-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*SV1:*:*:*) + echo sv1-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + *:UNICOS/mp:*:*) + echo craynv-cray-unicosmp${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + F30[01]:UNIX_System_V:*:* | F700:UNIX_System_V:*:*) + FUJITSU_PROC=`uname -m | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'` + FUJITSU_REL=`echo ${UNAME_RELEASE} | sed -e 's/ /_/'` + echo "${FUJITSU_PROC}-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}" + exit 0 ;; + 5000:UNIX_System_V:4.*:*) + FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'` + FUJITSU_REL=`echo ${UNAME_RELEASE} | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/ /_/'` + echo "sparc-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}" + exit 0 ;; + i*86:BSD/386:*:* | i*86:BSD/OS:*:* | *:Ascend\ Embedded/OS:*:*) + echo ${UNAME_MACHINE}-pc-bsdi${UNAME_RELEASE} + exit 0 ;; + sparc*:BSD/OS:*:*) + echo sparc-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:BSD/OS:*:*) + echo ${UNAME_MACHINE}-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:FreeBSD:*:*) + echo ${UNAME_MACHINE}-unknown-freebsd`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'` + exit 0 ;; + i*:CYGWIN*:*) + echo ${UNAME_MACHINE}-pc-cygwin + exit 0 ;; + i*:MINGW*:*) + echo ${UNAME_MACHINE}-pc-mingw32 + exit 0 ;; + i*:PW*:*) + echo ${UNAME_MACHINE}-pc-pw32 + exit 0 ;; + x86:Interix*:[34]*) + echo i586-pc-interix${UNAME_RELEASE}|sed -e 's/\..*//' + exit 0 ;; + [345]86:Windows_95:* | [345]86:Windows_98:* | [345]86:Windows_NT:*) + echo i${UNAME_MACHINE}-pc-mks + exit 0 ;; + i*:Windows_NT*:* | Pentium*:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # It also conflicts with pre-2.0 versions of AT&T UWIN. Should we + # UNAME_MACHINE based on the output of uname instead of i386? + echo i586-pc-interix + exit 0 ;; + i*:UWIN*:*) + echo ${UNAME_MACHINE}-pc-uwin + exit 0 ;; + p*:CYGWIN*:*) + echo powerpcle-unknown-cygwin + exit 0 ;; + prep*:SunOS:5.*:*) + echo powerpcle-unknown-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + *:GNU:*:*) + # the GNU system + echo `echo ${UNAME_MACHINE}|sed -e 's,[-/].*$,,'`-unknown-gnu`echo ${UNAME_RELEASE}|sed -e 's,/.*$,,'` + exit 0 ;; + *:GNU/*:*:*) + # other systems with GNU libc and userland + echo ${UNAME_MACHINE}-unknown-`echo ${UNAME_SYSTEM} | sed 's,^[^/]*/,,' | tr '[A-Z]' '[a-z]'``echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'`-gnu + exit 0 ;; + i*86:Minix:*:*) + echo ${UNAME_MACHINE}-pc-minix + exit 0 ;; + arm*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + cris:Linux:*:*) + echo cris-axis-linux-gnu + exit 0 ;; + ia64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + m32r*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + m68*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + mips:Linux:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #undef CPU + #undef mips + #undef mipsel + #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) + CPU=mipsel + #else + #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) + CPU=mips + #else + CPU= + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=` + test x"${CPU}" != x && echo "${CPU}-unknown-linux-gnu" && exit 0 + ;; + mips64:Linux:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #undef CPU + #undef mips64 + #undef mips64el + #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) + CPU=mips64el + #else + #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) + CPU=mips64 + #else + CPU= + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=` + test x"${CPU}" != x && echo "${CPU}-unknown-linux-gnu" && exit 0 + ;; + ppc:Linux:*:*) + echo powerpc-unknown-linux-gnu + exit 0 ;; + ppc64:Linux:*:*) + echo powerpc64-unknown-linux-gnu + exit 0 ;; + alpha:Linux:*:*) + case `sed -n '/^cpu model/s/^.*: \(.*\)/\1/p' < /proc/cpuinfo` in + EV5) UNAME_MACHINE=alphaev5 ;; + EV56) UNAME_MACHINE=alphaev56 ;; + PCA56) UNAME_MACHINE=alphapca56 ;; + PCA57) UNAME_MACHINE=alphapca56 ;; + EV6) UNAME_MACHINE=alphaev6 ;; + EV67) UNAME_MACHINE=alphaev67 ;; + EV68*) UNAME_MACHINE=alphaev68 ;; + esac + objdump --private-headers /bin/sh | grep ld.so.1 >/dev/null + if test "$?" = 0 ; then LIBC="libc1" ; else LIBC="" ; fi + echo ${UNAME_MACHINE}-unknown-linux-gnu${LIBC} + exit 0 ;; + parisc:Linux:*:* | hppa:Linux:*:*) + # Look for CPU level + case `grep '^cpu[^a-z]*:' /proc/cpuinfo 2>/dev/null | cut -d' ' -f2` in + PA7*) echo hppa1.1-unknown-linux-gnu ;; + PA8*) echo hppa2.0-unknown-linux-gnu ;; + *) echo hppa-unknown-linux-gnu ;; + esac + exit 0 ;; + parisc64:Linux:*:* | hppa64:Linux:*:*) + echo hppa64-unknown-linux-gnu + exit 0 ;; + s390:Linux:*:* | s390x:Linux:*:*) + echo ${UNAME_MACHINE}-ibm-linux + exit 0 ;; + sh64*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + sh*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + sparc:Linux:*:* | sparc64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + x86_64:Linux:*:*) + echo x86_64-unknown-linux-gnu + exit 0 ;; + i*86:Linux:*:*) + # The BFD linker knows what the default object file format is, so + # first see if it will tell us. cd to the root directory to prevent + # problems with other programs or directories called `ld' in the path. + # Set LC_ALL=C to ensure ld outputs messages in English. + ld_supported_targets=`cd /; LC_ALL=C ld --help 2>&1 \ + | sed -ne '/supported targets:/!d + s/[ ][ ]*/ /g + s/.*supported targets: *// + s/ .*// + p'` + case "$ld_supported_targets" in + elf32-i386) + TENTATIVE="${UNAME_MACHINE}-pc-linux-gnu" + ;; + a.out-i386-linux) + echo "${UNAME_MACHINE}-pc-linux-gnuaout" + exit 0 ;; + coff-i386) + echo "${UNAME_MACHINE}-pc-linux-gnucoff" + exit 0 ;; + "") + # Either a pre-BFD a.out linker (linux-gnuoldld) or + # one that does not give us useful --help. + echo "${UNAME_MACHINE}-pc-linux-gnuoldld" + exit 0 ;; + esac + # Determine whether the default compiler is a.out or elf + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + #ifdef __ELF__ + # ifdef __GLIBC__ + # if __GLIBC__ >= 2 + LIBC=gnu + # else + LIBC=gnulibc1 + # endif + # else + LIBC=gnulibc1 + # endif + #else + #ifdef __INTEL_COMPILER + LIBC=gnu + #else + LIBC=gnuaout + #endif + #endif + #ifdef __dietlibc__ + LIBC=dietlibc + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=` + test x"${LIBC}" != x && echo "${UNAME_MACHINE}-pc-linux-${LIBC}" && exit 0 + test x"${TENTATIVE}" != x && echo "${TENTATIVE}" && exit 0 + ;; + i*86:DYNIX/ptx:4*:*) + # ptx 4.0 does uname -s correctly, with DYNIX/ptx in there. + # earlier versions are messed up and put the nodename in both + # sysname and nodename. + echo i386-sequent-sysv4 + exit 0 ;; + i*86:UNIX_SV:4.2MP:2.*) + # Unixware is an offshoot of SVR4, but it has its own version + # number series starting with 2... + # I am not positive that other SVR4 systems won't match this, + # I just have to hope. -- rms. + # Use sysv4.2uw... so that sysv4* matches it. + echo ${UNAME_MACHINE}-pc-sysv4.2uw${UNAME_VERSION} + exit 0 ;; + i*86:OS/2:*:*) + # If we were able to find `uname', then EMX Unix compatibility + # is probably installed. + echo ${UNAME_MACHINE}-pc-os2-emx + exit 0 ;; + i*86:XTS-300:*:STOP) + echo ${UNAME_MACHINE}-unknown-stop + exit 0 ;; + i*86:atheos:*:*) + echo ${UNAME_MACHINE}-unknown-atheos + exit 0 ;; + i*86:syllable:*:*) + echo ${UNAME_MACHINE}-pc-syllable + exit 0 ;; + i*86:LynxOS:2.*:* | i*86:LynxOS:3.[01]*:* | i*86:LynxOS:4.0*:*) + echo i386-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + i*86:*DOS:*:*) + echo ${UNAME_MACHINE}-pc-msdosdjgpp + exit 0 ;; + i*86:*:4.*:* | i*86:SYSTEM_V:4.*:*) + UNAME_REL=`echo ${UNAME_RELEASE} | sed 's/\/MP$//'` + if grep Novell /usr/include/link.h >/dev/null 2>/dev/null; then + echo ${UNAME_MACHINE}-univel-sysv${UNAME_REL} + else + echo ${UNAME_MACHINE}-pc-sysv${UNAME_REL} + fi + exit 0 ;; + i*86:*:5:[78]*) + case `/bin/uname -X | grep "^Machine"` in + *486*) UNAME_MACHINE=i486 ;; + *Pentium) UNAME_MACHINE=i586 ;; + *Pent*|*Celeron) UNAME_MACHINE=i686 ;; + esac + echo ${UNAME_MACHINE}-unknown-sysv${UNAME_RELEASE}${UNAME_SYSTEM}${UNAME_VERSION} + exit 0 ;; + i*86:*:3.2:*) + if test -f /usr/options/cb.name; then + UNAME_REL=`sed -n 's/.*Version //p' /dev/null >/dev/null ; then + UNAME_REL=`(/bin/uname -X|grep Release|sed -e 's/.*= //')` + (/bin/uname -X|grep i80486 >/dev/null) && UNAME_MACHINE=i486 + (/bin/uname -X|grep '^Machine.*Pentium' >/dev/null) \ + && UNAME_MACHINE=i586 + (/bin/uname -X|grep '^Machine.*Pent *II' >/dev/null) \ + && UNAME_MACHINE=i686 + (/bin/uname -X|grep '^Machine.*Pentium Pro' >/dev/null) \ + && UNAME_MACHINE=i686 + echo ${UNAME_MACHINE}-pc-sco$UNAME_REL + else + echo ${UNAME_MACHINE}-pc-sysv32 + fi + exit 0 ;; + pc:*:*:*) + # Left here for compatibility: + # uname -m prints for DJGPP always 'pc', but it prints nothing about + # the processor, so we play safe by assuming i386. + echo i386-pc-msdosdjgpp + exit 0 ;; + Intel:Mach:3*:*) + echo i386-pc-mach3 + exit 0 ;; + paragon:*:*:*) + echo i860-intel-osf1 + exit 0 ;; + i860:*:4.*:*) # i860-SVR4 + if grep Stardent /usr/include/sys/uadmin.h >/dev/null 2>&1 ; then + echo i860-stardent-sysv${UNAME_RELEASE} # Stardent Vistra i860-SVR4 + else # Add other i860-SVR4 vendors below as they are discovered. + echo i860-unknown-sysv${UNAME_RELEASE} # Unknown i860-SVR4 + fi + exit 0 ;; + mini*:CTIX:SYS*5:*) + # "miniframe" + echo m68010-convergent-sysv + exit 0 ;; + mc68k:UNIX:SYSTEM5:3.51m) + echo m68k-convergent-sysv + exit 0 ;; + M680?0:D-NIX:5.3:*) + echo m68k-diab-dnix + exit 0 ;; + M68*:*:R3V[5678]*:*) + test -r /sysV68 && echo 'm68k-motorola-sysv' && exit 0 ;; + 3[345]??:*:4.0:3.0 | 3[34]??A:*:4.0:3.0 | 3[34]??,*:*:4.0:3.0 | 3[34]??/*:*:4.0:3.0 | 4400:*:4.0:3.0 | 4850:*:4.0:3.0 | SKA40:*:4.0:3.0 | SDS2:*:4.0:3.0 | SHG2:*:4.0:3.0 | S7501*:*:4.0:3.0) + OS_REL='' + test -r /etc/.relid \ + && OS_REL=.`sed -n 's/[^ ]* [^ ]* \([0-9][0-9]\).*/\1/p' < /etc/.relid` + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4.3${OS_REL} && exit 0 + /bin/uname -p 2>/dev/null | /bin/grep entium >/dev/null \ + && echo i586-ncr-sysv4.3${OS_REL} && exit 0 ;; + 3[34]??:*:4.0:* | 3[34]??,*:*:4.0:*) + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4 && exit 0 ;; + m68*:LynxOS:2.*:* | m68*:LynxOS:3.0*:*) + echo m68k-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + mc68030:UNIX_System_V:4.*:*) + echo m68k-atari-sysv4 + exit 0 ;; + TSUNAMI:LynxOS:2.*:*) + echo sparc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + rs6000:LynxOS:2.*:*) + echo rs6000-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + PowerPC:LynxOS:2.*:* | PowerPC:LynxOS:3.[01]*:* | PowerPC:LynxOS:4.0*:*) + echo powerpc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + SM[BE]S:UNIX_SV:*:*) + echo mips-dde-sysv${UNAME_RELEASE} + exit 0 ;; + RM*:ReliantUNIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + RM*:SINIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + *:SINIX-*:*:*) + if uname -p 2>/dev/null >/dev/null ; then + UNAME_MACHINE=`(uname -p) 2>/dev/null` + echo ${UNAME_MACHINE}-sni-sysv4 + else + echo ns32k-sni-sysv + fi + exit 0 ;; + PENTIUM:*:4.0*:*) # Unisys `ClearPath HMP IX 4000' SVR4/MP effort + # says + echo i586-unisys-sysv4 + exit 0 ;; + *:UNIX_System_V:4*:FTX*) + # From Gerald Hewes . + # How about differentiating between stratus architectures? -djm + echo hppa1.1-stratus-sysv4 + exit 0 ;; + *:*:*:FTX*) + # From seanf@swdc.stratus.com. + echo i860-stratus-sysv4 + exit 0 ;; + *:VOS:*:*) + # From Paul.Green@stratus.com. + echo hppa1.1-stratus-vos + exit 0 ;; + mc68*:A/UX:*:*) + echo m68k-apple-aux${UNAME_RELEASE} + exit 0 ;; + news*:NEWS-OS:6*:*) + echo mips-sony-newsos6 + exit 0 ;; + R[34]000:*System_V*:*:* | R4000:UNIX_SYSV:*:* | R*000:UNIX_SV:*:*) + if [ -d /usr/nec ]; then + echo mips-nec-sysv${UNAME_RELEASE} + else + echo mips-unknown-sysv${UNAME_RELEASE} + fi + exit 0 ;; + BeBox:BeOS:*:*) # BeOS running on hardware made by Be, PPC only. + echo powerpc-be-beos + exit 0 ;; + BeMac:BeOS:*:*) # BeOS running on Mac or Mac clone, PPC only. + echo powerpc-apple-beos + exit 0 ;; + BePC:BeOS:*:*) # BeOS running on Intel PC compatible. + echo i586-pc-beos + exit 0 ;; + SX-4:SUPER-UX:*:*) + echo sx4-nec-superux${UNAME_RELEASE} + exit 0 ;; + SX-5:SUPER-UX:*:*) + echo sx5-nec-superux${UNAME_RELEASE} + exit 0 ;; + SX-6:SUPER-UX:*:*) + echo sx6-nec-superux${UNAME_RELEASE} + exit 0 ;; + Power*:Rhapsody:*:*) + echo powerpc-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Rhapsody:*:*) + echo ${UNAME_MACHINE}-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Darwin:*:*) + UNAME_PROCESSOR=`uname -p` || UNAME_PROCESSOR=unknown + case $UNAME_PROCESSOR in + *86) UNAME_PROCESSOR=i686 ;; + unknown) UNAME_PROCESSOR=powerpc ;; + esac + echo ${UNAME_PROCESSOR}-apple-darwin${UNAME_RELEASE} + exit 0 ;; + *:procnto*:*:* | *:QNX:[0123456789]*:*) + UNAME_PROCESSOR=`uname -p` + if test "$UNAME_PROCESSOR" = "x86"; then + UNAME_PROCESSOR=i386 + UNAME_MACHINE=pc + fi + echo ${UNAME_PROCESSOR}-${UNAME_MACHINE}-nto-qnx${UNAME_RELEASE} + exit 0 ;; + *:QNX:*:4*) + echo i386-pc-qnx + exit 0 ;; + NSR-?:NONSTOP_KERNEL:*:*) + echo nsr-tandem-nsk${UNAME_RELEASE} + exit 0 ;; + *:NonStop-UX:*:*) + echo mips-compaq-nonstopux + exit 0 ;; + BS2000:POSIX*:*:*) + echo bs2000-siemens-sysv + exit 0 ;; + DS/*:UNIX_System_V:*:*) + echo ${UNAME_MACHINE}-${UNAME_SYSTEM}-${UNAME_RELEASE} + exit 0 ;; + *:Plan9:*:*) + # "uname -m" is not consistent, so use $cputype instead. 386 + # is converted to i386 for consistency with other x86 + # operating systems. + if test "$cputype" = "386"; then + UNAME_MACHINE=i386 + else + UNAME_MACHINE="$cputype" + fi + echo ${UNAME_MACHINE}-unknown-plan9 + exit 0 ;; + *:TOPS-10:*:*) + echo pdp10-unknown-tops10 + exit 0 ;; + *:TENEX:*:*) + echo pdp10-unknown-tenex + exit 0 ;; + KS10:TOPS-20:*:* | KL10:TOPS-20:*:* | TYPE4:TOPS-20:*:*) + echo pdp10-dec-tops20 + exit 0 ;; + XKL-1:TOPS-20:*:* | TYPE5:TOPS-20:*:*) + echo pdp10-xkl-tops20 + exit 0 ;; + *:TOPS-20:*:*) + echo pdp10-unknown-tops20 + exit 0 ;; + *:ITS:*:*) + echo pdp10-unknown-its + exit 0 ;; + SEI:*:*:SEIUX) + echo mips-sei-seiux${UNAME_RELEASE} + exit 0 ;; + *:DragonFly:*:*) + echo ${UNAME_MACHINE}-unknown-dragonfly`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'` + exit 0 ;; + *:*VMS:*:*) + UNAME_MACHINE=`(uname -p) 2>/dev/null` + case "${UNAME_MACHINE}" in + A*) echo alpha-dec-vms && exit 0 ;; + I*) echo ia64-dec-vms && exit 0 ;; + V*) echo vax-dec-vms && exit 0 ;; + esac +esac + +#echo '(No uname command or uname output not recognized.)' 1>&2 +#echo "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" 1>&2 + +eval $set_cc_for_build +cat >$dummy.c < +# include +#endif +main () +{ +#if defined (sony) +#if defined (MIPSEB) + /* BFD wants "bsd" instead of "newsos". Perhaps BFD should be changed, + I don't know.... */ + printf ("mips-sony-bsd\n"); exit (0); +#else +#include + printf ("m68k-sony-newsos%s\n", +#ifdef NEWSOS4 + "4" +#else + "" +#endif + ); exit (0); +#endif +#endif + +#if defined (__arm) && defined (__acorn) && defined (__unix) + printf ("arm-acorn-riscix"); exit (0); +#endif + +#if defined (hp300) && !defined (hpux) + printf ("m68k-hp-bsd\n"); exit (0); +#endif + +#if defined (NeXT) +#if !defined (__ARCHITECTURE__) +#define __ARCHITECTURE__ "m68k" +#endif + int version; + version=`(hostinfo | sed -n 's/.*NeXT Mach \([0-9]*\).*/\1/p') 2>/dev/null`; + if (version < 4) + printf ("%s-next-nextstep%d\n", __ARCHITECTURE__, version); + else + printf ("%s-next-openstep%d\n", __ARCHITECTURE__, version); + exit (0); +#endif + +#if defined (MULTIMAX) || defined (n16) +#if defined (UMAXV) + printf ("ns32k-encore-sysv\n"); exit (0); +#else +#if defined (CMU) + printf ("ns32k-encore-mach\n"); exit (0); +#else + printf ("ns32k-encore-bsd\n"); exit (0); +#endif +#endif +#endif + +#if defined (__386BSD__) + printf ("i386-pc-bsd\n"); exit (0); +#endif + +#if defined (sequent) +#if defined (i386) + printf ("i386-sequent-dynix\n"); exit (0); +#endif +#if defined (ns32000) + printf ("ns32k-sequent-dynix\n"); exit (0); +#endif +#endif + +#if defined (_SEQUENT_) + struct utsname un; + + uname(&un); + + if (strncmp(un.version, "V2", 2) == 0) { + printf ("i386-sequent-ptx2\n"); exit (0); + } + if (strncmp(un.version, "V1", 2) == 0) { /* XXX is V1 correct? */ + printf ("i386-sequent-ptx1\n"); exit (0); + } + printf ("i386-sequent-ptx\n"); exit (0); + +#endif + +#if defined (vax) +# if !defined (ultrix) +# include +# if defined (BSD) +# if BSD == 43 + printf ("vax-dec-bsd4.3\n"); exit (0); +# else +# if BSD == 199006 + printf ("vax-dec-bsd4.3reno\n"); exit (0); +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# endif +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# else + printf ("vax-dec-ultrix\n"); exit (0); +# endif +#endif + +#if defined (alliant) && defined (i860) + printf ("i860-alliant-bsd\n"); exit (0); +#endif + + exit (1); +} +EOF + +$CC_FOR_BUILD -o $dummy $dummy.c 2>/dev/null && $dummy && exit 0 + +# Apollos put the system type in the environment. + +test -d /usr/apollo && { echo ${ISP}-apollo-${SYSTYPE}; exit 0; } + +# Convex versions that predate uname can use getsysinfo(1) + +if [ -x /usr/convex/getsysinfo ] +then + case `getsysinfo -f cpu_type` in + c1*) + echo c1-convex-bsd + exit 0 ;; + c2*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + c34*) + echo c34-convex-bsd + exit 0 ;; + c38*) + echo c38-convex-bsd + exit 0 ;; + c4*) + echo c4-convex-bsd + exit 0 ;; + esac +fi + +cat >&2 < in order to provide the needed +information to handle your system. + +config.guess timestamp = $timestamp + +uname -m = `(uname -m) 2>/dev/null || echo unknown` +uname -r = `(uname -r) 2>/dev/null || echo unknown` +uname -s = `(uname -s) 2>/dev/null || echo unknown` +uname -v = `(uname -v) 2>/dev/null || echo unknown` + +/usr/bin/uname -p = `(/usr/bin/uname -p) 2>/dev/null` +/bin/uname -X = `(/bin/uname -X) 2>/dev/null` + +hostinfo = `(hostinfo) 2>/dev/null` +/bin/universe = `(/bin/universe) 2>/dev/null` +/usr/bin/arch -k = `(/usr/bin/arch -k) 2>/dev/null` +/bin/arch = `(/bin/arch) 2>/dev/null` +/usr/bin/oslevel = `(/usr/bin/oslevel) 2>/dev/null` +/usr/convex/getsysinfo = `(/usr/convex/getsysinfo) 2>/dev/null` + +UNAME_MACHINE = ${UNAME_MACHINE} +UNAME_RELEASE = ${UNAME_RELEASE} +UNAME_SYSTEM = ${UNAME_SYSTEM} +UNAME_VERSION = ${UNAME_VERSION} +EOF + +exit 1 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "timestamp='" +# time-stamp-format: "%:y-%02m-%02d" +# time-stamp-end: "'" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.log new file mode 100755 index 00000000..239d398b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.log @@ -0,0 +1,664 @@ +This file contains any messages produced by compilers while +running configure, to aid debugging if configure makes a mistake. + +It was created by configure, which was +generated by GNU Autoconf 2.59. Invocation command line was + + $ ./configure --prefix=/usr/local --prefix=/usr/local --cache-file=/dev/null --srcdir=. --cache-file=/dev/null --srcdir=. + +## --------- ## +## Platform. ## +## --------- ## + +hostname = mcluster02 +uname -m = x86_64 +uname -r = 2.6.9-34.ELsmp +uname -s = Linux +uname -v = #1 SMP Fri Feb 24 16:56:28 EST 2006 + +/usr/bin/uname -p = unknown +/bin/uname -X = unknown + +/bin/arch = x86_64 +/usr/bin/arch -k = unknown +/usr/convex/getsysinfo = unknown +hostinfo = unknown +/bin/machine = unknown +/usr/bin/oslevel = unknown +/bin/universe = unknown + +PATH: /storage/appl/n1ge6u7/bin/lx24-amd64 +PATH: /opt/sun/n1gc/bin +PATH: /usr/local/bin +PATH: /bin +PATH: /usr/bin +PATH: /opt/c3-4/ +PATH: /usr/X11R6/bin +PATH: /usr/local/bin +PATH: /usr/local/bin/X11R5 +PATH: /usr/local/X11R5/bin +PATH: /usr/X11R6/bin +PATH: /home/rabani/Develop/perl/GeneXPress +PATH: /home/rabani/Develop/perl/Genome +PATH: /home/rabani/Develop/perl/Lib +PATH: /home/rabani/Develop/perl/Parsers +PATH: /home/rabani/Develop/perl/RNA +PATH: /home/rabani/Develop/perl/Sequence +PATH: /home/rabani/Develop/perl/System +PATH: /home/rabani/Develop/perl/Web +PATH: /home/rabani/Develop/perl/Web/DataDir +PATH: /home/rabani/Develop/genie_release64/Programs +PATH: /storage/appl/matlab14.3/bin +PATH: /home/rabani + + +## ----------- ## +## Core tests. ## +## ----------- ## + +configure:1349: checking build system type +configure:1367: result: x86_64-unknown-linux-gnu +configure:1375: checking host system type +configure:1389: result: x86_64-unknown-linux-gnu +configure:1487: checking for gcc +configure:1503: found /usr/bin/gcc +configure:1513: result: gcc +configure:1757: checking for C compiler version +configure:1760: gcc --version &5 +gcc (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:1763: $? = 0 +configure:1765: gcc -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:1768: $? = 0 +configure:1770: gcc -V &5 +gcc: `-V' option must have argument +configure:1773: $? = 1 +configure:1796: checking for C compiler default output file name +configure:1799: gcc conftest.c >&5 +configure:1802: $? = 0 +configure:1848: result: a.out +configure:1853: checking whether the C compiler works +configure:1859: ./a.out +configure:1862: $? = 0 +configure:1879: result: yes +configure:1886: checking whether we are cross compiling +configure:1888: result: no +configure:1891: checking for suffix of executables +configure:1893: gcc -o conftest conftest.c >&5 +configure:1896: $? = 0 +configure:1921: result: +configure:1927: checking for suffix of object files +configure:1948: gcc -c conftest.c >&5 +configure:1951: $? = 0 +configure:1973: result: o +configure:1977: checking whether we are using the GNU C compiler +configure:2001: gcc -c conftest.c >&5 +configure:2007: $? = 0 +configure:2011: test -z + || test ! -s conftest.err +configure:2014: $? = 0 +configure:2017: test -s conftest.o +configure:2020: $? = 0 +configure:2033: result: yes +configure:2039: checking whether gcc accepts -g +configure:2060: gcc -c -g conftest.c >&5 +configure:2066: $? = 0 +configure:2070: test -z + || test ! -s conftest.err +configure:2073: $? = 0 +configure:2076: test -s conftest.o +configure:2079: $? = 0 +configure:2090: result: yes +configure:2107: checking for gcc option to accept ANSI C +configure:2177: gcc -c -g -O2 conftest.c >&5 +configure:2183: $? = 0 +configure:2187: test -z + || test ! -s conftest.err +configure:2190: $? = 0 +configure:2193: test -s conftest.o +configure:2196: $? = 0 +configure:2214: result: none needed +configure:2232: gcc -c -g -O2 conftest.c >&5 +conftest.c:2: error: syntax error before "me" +configure:2238: $? = 1 +configure: failed program was: +| #ifndef __cplusplus +| choke me +| #endif +configure:2376: checking how to run the C preprocessor +configure:2411: gcc -E conftest.c +configure:2417: $? = 0 +configure:2449: gcc -E conftest.c +conftest.c:10:28: ac_nonexistent.h: No such file or directory +configure:2455: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "" +| #define PACKAGE_TARNAME "" +| #define PACKAGE_VERSION "" +| #define PACKAGE_STRING "" +| #define PACKAGE_BUGREPORT "" +| #define LINUX 1 +| /* end confdefs.h. */ +| #include +configure:2494: result: gcc -E +configure:2518: gcc -E conftest.c +configure:2524: $? = 0 +configure:2556: gcc -E conftest.c +conftest.c:10:28: ac_nonexistent.h: No such file or directory +configure:2562: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "" +| #define PACKAGE_TARNAME "" +| #define PACKAGE_VERSION "" +| #define PACKAGE_STRING "" +| #define PACKAGE_BUGREPORT "" +| #define LINUX 1 +| /* end confdefs.h. */ +| #include +configure:2657: checking for g++ +configure:2673: found /usr/bin/g++ +configure:2683: result: g++ +configure:2699: checking for C++ compiler version +configure:2702: g++ --version &5 +g++ (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:2705: $? = 0 +configure:2707: g++ -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:2710: $? = 0 +configure:2712: g++ -V &5 +g++: `-V' option must have argument +configure:2715: $? = 1 +configure:2718: checking whether we are using the GNU C++ compiler +configure:2742: g++ -c conftest.cc >&5 +configure:2748: $? = 0 +configure:2752: test -z + || test ! -s conftest.err +configure:2755: $? = 0 +configure:2758: test -s conftest.o +configure:2761: $? = 0 +configure:2774: result: yes +configure:2780: checking whether g++ accepts -g +configure:2801: g++ -c -g conftest.cc >&5 +configure:2807: $? = 0 +configure:2811: test -z + || test ! -s conftest.err +configure:2814: $? = 0 +configure:2817: test -s conftest.o +configure:2820: $? = 0 +configure:2831: result: yes +configure:2873: g++ -c -g -O2 conftest.cc >&5 +configure:2879: $? = 0 +configure:2883: test -z + || test ! -s conftest.err +configure:2886: $? = 0 +configure:2889: test -s conftest.o +configure:2892: $? = 0 +configure:2918: g++ -c -g -O2 conftest.cc >&5 +conftest.cc: In function `int main()': +conftest.cc:14: error: `exit' was not declared in this scope +configure:2924: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "" +| #define PACKAGE_TARNAME "" +| #define PACKAGE_VERSION "" +| #define PACKAGE_STRING "" +| #define PACKAGE_BUGREPORT "" +| #define LINUX 1 +| /* end confdefs.h. */ +| +| int +| main () +| { +| exit (42); +| ; +| return 0; +| } +configure:2873: g++ -c -g -O2 conftest.cc >&5 +configure:2879: $? = 0 +configure:2883: test -z + || test ! -s conftest.err +configure:2886: $? = 0 +configure:2889: test -s conftest.o +configure:2892: $? = 0 +configure:2918: g++ -c -g -O2 conftest.cc >&5 +configure:2924: $? = 0 +configure:2928: test -z + || test ! -s conftest.err +configure:2931: $? = 0 +configure:2934: test -s conftest.o +configure:2937: $? = 0 +configure:3001: checking for ranlib +configure:3017: found /usr/bin/ranlib +configure:3028: result: ranlib +configure:3053: checking for a BSD-compatible install +configure:3108: result: /usr/bin/install -c +configure:3121: checking for find +configure:3137: found /usr/bin/find +configure:3148: result: find +configure:3157: checking for makedepend +configure:3173: found /usr/X11R6/bin/makedepend +configure:3184: result: makedepend +configure:3192: checking for dlopen in -ldl +configure:3222: gcc -o conftest -g -O2 conftest.c -ldl >&5 +configure:3228: $? = 0 +configure:3232: test -z + || test ! -s conftest.err +configure:3235: $? = 0 +configure:3238: test -s conftest +configure:3241: $? = 0 +configure:3254: result: yes +configure:3269: checking for X +configure:3499: result: libraries /usr/X11R6/lib64, headers /usr/X11R6/include +configure:3671: gcc -o conftest -g -O2 conftest.c -L/usr/X11R6/lib64 -lX11 >&5 +configure:3677: $? = 0 +configure:3681: test -z + || test ! -s conftest.err +configure:3684: $? = 0 +configure:3687: test -s conftest +configure:3690: $? = 0 +configure:3848: checking for gethostbyname +configure:3905: gcc -o conftest -g -O2 conftest.c >&5 +configure:3911: $? = 0 +configure:3915: test -z + || test ! -s conftest.err +configure:3918: $? = 0 +configure:3921: test -s conftest +configure:3924: $? = 0 +configure:3936: result: yes +configure:4087: checking for connect +configure:4144: gcc -o conftest -g -O2 conftest.c >&5 +configure:4150: $? = 0 +configure:4154: test -z + || test ! -s conftest.err +configure:4157: $? = 0 +configure:4160: test -s conftest +configure:4163: $? = 0 +configure:4175: result: yes +configure:4250: checking for remove +configure:4307: gcc -o conftest -g -O2 conftest.c >&5 +configure:4313: $? = 0 +configure:4317: test -z + || test ! -s conftest.err +configure:4320: $? = 0 +configure:4323: test -s conftest +configure:4326: $? = 0 +configure:4338: result: yes +configure:4413: checking for shmat +configure:4470: gcc -o conftest -g -O2 conftest.c >&5 +configure:4476: $? = 0 +configure:4480: test -z + || test ! -s conftest.err +configure:4483: $? = 0 +configure:4486: test -s conftest +configure:4489: $? = 0 +configure:4501: result: yes +configure:4585: checking for IceConnectionNumber in -lICE +configure:4615: gcc -o conftest -g -O2 -L/usr/X11R6/lib64 conftest.c -lICE >&5 +configure:4621: $? = 0 +configure:4625: test -z + || test ! -s conftest.err +configure:4628: $? = 0 +configure:4631: test -s conftest +configure:4634: $? = 0 +configure:4647: result: yes +configure:4671: checking for main in -lm +configure:4695: gcc -o conftest -g -O2 -I/usr/X11R6/include -I/usr/local/include -L/usr/X11R6/lib64 -L/usr/local/lib conftest.c -lm >&5 +configure:4701: $? = 0 +configure:4705: test -z + || test ! -s conftest.err +configure:4708: $? = 0 +configure:4711: test -s conftest +configure:4714: $? = 0 +configure:4727: result: yes +configure:4741: checking for main in -lX11 +configure:4765: gcc -o conftest -g -O2 -I/usr/X11R6/include -I/usr/local/include -L/usr/X11R6/lib64 -L/usr/local/lib -lm conftest.c -lX11 >&5 +configure:4771: $? = 0 +configure:4775: test -z + || test ! -s conftest.err +configure:4778: $? = 0 +configure:4781: test -s conftest +configure:4784: $? = 0 +configure:4797: result: yes +configure:4806: checking for main in -lgd +configure:4830: gcc -o conftest -g -O2 -I/usr/X11R6/include -I/usr/local/include -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 conftest.c -lgd >&5 +configure:4836: $? = 0 +configure:4840: test -z + || test ! -s conftest.err +configure:4843: $? = 0 +configure:4846: test -s conftest +configure:4849: $? = 0 +configure:4862: result: yes +configure:4873: checking for gdImagePng +configure:4930: gcc -o conftest -g -O2 -I/usr/X11R6/include -I/usr/local/include -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd conftest.c >&5 +configure:4936: $? = 0 +configure:4940: test -z + || test ! -s conftest.err +configure:4943: $? = 0 +configure:4946: test -s conftest +configure:4949: $? = 0 +configure:4961: result: yes +configure:5225: checking for egrep +configure:5235: result: grep -E +configure:5240: checking for ANSI C header files +configure:5265: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5271: $? = 0 +configure:5275: test -z + || test ! -s conftest.err +configure:5278: $? = 0 +configure:5281: test -s conftest.o +configure:5284: $? = 0 +configure:5373: gcc -o conftest -g -O2 -I/usr/X11R6/include -I/usr/local/include -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd conftest.c >&5 +configure:5376: $? = 0 +configure:5378: ./conftest +configure:5381: $? = 0 +configure:5396: result: yes +configure:5420: checking for sys/types.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for sys/stat.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for stdlib.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for string.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for memory.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for strings.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for inttypes.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for stdint.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5420: checking for unistd.h +configure:5436: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5442: $? = 0 +configure:5446: test -z + || test ! -s conftest.err +configure:5449: $? = 0 +configure:5452: test -s conftest.o +configure:5455: $? = 0 +configure:5466: result: yes +configure:5492: checking limits.h usability +configure:5504: gcc -c -g -O2 -I/usr/X11R6/include -I/usr/local/include conftest.c >&5 +configure:5510: $? = 0 +configure:5514: test -z + || test ! -s conftest.err +configure:5517: $? = 0 +configure:5520: test -s conftest.o +configure:5523: $? = 0 +configure:5533: result: yes +configure:5537: checking limits.h presence +configure:5547: gcc -E conftest.c +configure:5553: $? = 0 +configure:5573: result: yes +configure:5608: checking for limits.h +configure:5615: result: yes +configure:5762: creating ./config.status + +## ---------------------- ## +## Running config.status. ## +## ---------------------- ## + +This file was extended by config.status, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = + CONFIG_HEADERS = + CONFIG_LINKS = + CONFIG_COMMANDS = + $ ./config.status + +on mcluster02 + +config.status:671: creating Makefile +config.status:671: creating demo/Makefile +config.status:671: creating g2_perl/Makefile.PL + +## ---------------- ## +## Cache variables. ## +## ---------------- ## + +ac_cv_build=x86_64-unknown-linux-gnu +ac_cv_build_alias=x86_64-unknown-linux-gnu +ac_cv_c_compiler_gnu=yes +ac_cv_cxx_compiler_gnu=yes +ac_cv_env_CC_set= +ac_cv_env_CC_value= +ac_cv_env_CFLAGS_set= +ac_cv_env_CFLAGS_value= +ac_cv_env_CPPFLAGS_set= +ac_cv_env_CPPFLAGS_value= +ac_cv_env_CPP_set= +ac_cv_env_CPP_value= +ac_cv_env_CXXFLAGS_set= +ac_cv_env_CXXFLAGS_value= +ac_cv_env_CXX_set= +ac_cv_env_CXX_value= +ac_cv_env_LDFLAGS_set= +ac_cv_env_LDFLAGS_value= +ac_cv_env_build_alias_set= +ac_cv_env_build_alias_value= +ac_cv_env_host_alias_set= +ac_cv_env_host_alias_value= +ac_cv_env_target_alias_set= +ac_cv_env_target_alias_value= +ac_cv_exeext= +ac_cv_func_connect=yes +ac_cv_func_gdImagePng=yes +ac_cv_func_gethostbyname=yes +ac_cv_func_remove=yes +ac_cv_func_shmat=yes +ac_cv_have_x='have_x=yes ac_x_includes=/usr/X11R6/include ac_x_libraries=/usr/X11R6/lib64' +ac_cv_header_inttypes_h=yes +ac_cv_header_limits_h=yes +ac_cv_header_memory_h=yes +ac_cv_header_stdc=yes +ac_cv_header_stdint_h=yes +ac_cv_header_stdlib_h=yes +ac_cv_header_string_h=yes +ac_cv_header_strings_h=yes +ac_cv_header_sys_stat_h=yes +ac_cv_header_sys_types_h=yes +ac_cv_header_unistd_h=yes +ac_cv_host=x86_64-unknown-linux-gnu +ac_cv_host_alias=x86_64-unknown-linux-gnu +ac_cv_lib_ICE_IceConnectionNumber=yes +ac_cv_lib_X11_main=yes +ac_cv_lib_dl_dlopen=yes +ac_cv_lib_gd_main=yes +ac_cv_lib_m_main=yes +ac_cv_objext=o +ac_cv_path_install='/usr/bin/install -c' +ac_cv_prog_CPP='gcc -E' +ac_cv_prog_FIND=find +ac_cv_prog_MAKEDEPEND=makedepend +ac_cv_prog_ac_ct_CC=gcc +ac_cv_prog_ac_ct_CXX=g++ +ac_cv_prog_ac_ct_RANLIB=ranlib +ac_cv_prog_cc_g=yes +ac_cv_prog_cc_stdc= +ac_cv_prog_cxx_g=yes +ac_cv_prog_egrep='grep -E' + +## ----------------- ## +## Output variables. ## +## ----------------- ## + +CC='gcc' +CFLAGS='-g -O2 -I/usr/X11R6/include -I/usr/local/include' +CPP='gcc -E' +CPPFLAGS='' +CXX='g++' +CXXFLAGS='-g -O2' +DEFS='-DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 ' +DO_FIG='' +DO_GD='' +DO_PS='' +DO_WIN32='#' +DO_X11='' +ECHO_C='' +ECHO_N='-n' +ECHO_T='' +EGREP='grep -E' +EXEEXT='' +FIND='find' +INSTALL_DATA='${INSTALL} -m 644' +INSTALL_PROGRAM='${INSTALL}' +INSTALL_SCRIPT='${INSTALL}' +LDFLAGS=' -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd' +LD_SHARED='ld' +LD_SHARED_EXT='so.0.$(G2_VERSION)' +LD_SHARED_FLAGS='-shared -soname libg2.so.0' +LD_SHARED_OPT='' +LIBOBJS='' +LIBS='' +LTLIBOBJS='' +MAKEDEPEND='makedepend' +OBJEXT='o' +PACKAGE_BUGREPORT='' +PACKAGE_NAME='' +PACKAGE_STRING='' +PACKAGE_TARNAME='' +PACKAGE_VERSION='' +PATH_SEPARATOR=':' +RANLIB='ranlib' +SHELL='/bin/sh' +X_CFLAGS=' -I/usr/X11R6/include' +X_EXTRA_LIBS='' +X_LIBS=' -L/usr/X11R6/lib64' +X_PRE_LIBS=' -lSM -lICE' +ac_ct_CC='gcc' +ac_ct_CXX='g++' +ac_ct_RANLIB='ranlib' +bindir='${exec_prefix}/bin' +build='x86_64-unknown-linux-gnu' +build_alias='' +build_cpu='x86_64' +build_os='linux-gnu' +build_vendor='unknown' +datadir='${prefix}/share' +exec_prefix='${prefix}' +host='x86_64-unknown-linux-gnu' +host_alias='' +host_cpu='x86_64' +host_os='linux-gnu' +host_vendor='unknown' +includedir='${prefix}/include' +infodir='${prefix}/info' +libdir='${exec_prefix}/lib' +libexecdir='${exec_prefix}/libexec' +localstatedir='${prefix}/var' +mandir='${prefix}/man' +oldincludedir='/usr/include' +prefix='/usr/local' +program_transform_name='s,x,x,' +sbindir='${exec_prefix}/sbin' +sharedstatedir='${prefix}/com' +sysconfdir='${prefix}/etc' +target_alias='' + +## ----------- ## +## confdefs.h. ## +## ----------- ## + +#define DO_FIG 1 +#define DO_GD 1 +#define DO_PS 1 +#define DO_X11 1 +#define HAVE_INTTYPES_H 1 +#define HAVE_LIMITS_H 1 +#define HAVE_MEMORY_H 1 +#define HAVE_STDINT_H 1 +#define HAVE_STDLIB_H 1 +#define HAVE_STRINGS_H 1 +#define HAVE_STRING_H 1 +#define HAVE_SYS_STAT_H 1 +#define HAVE_SYS_TYPES_H 1 +#define HAVE_UNISTD_H 1 +#define LINUX 1 +#define PACKAGE_BUGREPORT "" +#define PACKAGE_NAME "" +#define PACKAGE_STRING "" +#define PACKAGE_TARNAME "" +#define PACKAGE_VERSION "" +#define STDC_HEADERS 1 +#endif +#ifdef __cplusplus +extern "C" void std::exit (int) throw (); using std::exit; + +configure: exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.status b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.status new file mode 100755 index 00000000..6bd9c103 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/config.status @@ -0,0 +1,745 @@ +#! /bin/sh +# Generated by configure. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=${CONFIG_SHELL-/bin/sh} +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-) + sed '=' <$as_myself | + sed ' + N + s,$,-, + : loop + s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3, + t loop + s,-$,, + s,^['$as_cr_digits']*\n,, + ' >$as_me.lineno && + chmod +x $as_me.lineno || + { { echo "$as_me:$LINENO: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&5 +echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2;} + { (exit 1); exit 1; }; } + + # Don't try to exec as it changes $[0], causing all sort of problems + # (the dirname of $[0] is not the place where we might find the + # original and so on. Autoconf is especially sensible to this). + . ./$as_me.lineno + # Exit status is that of the last command. + exit +} + + +case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in + *c*,-n*) ECHO_N= ECHO_C=' +' ECHO_T=' ' ;; + *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;; + *) ECHO_N= ECHO_C='\c' ECHO_T= ;; +esac + +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +rm -f conf$$ conf$$.exe conf$$.file +echo >conf$$.file +if ln -s conf$$.file conf$$ 2>/dev/null; then + # We could just check for DJGPP; but this test a) works b) is more generic + # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04). + if test -f conf$$.exe; then + # Don't use ln at all; we don't have any links + as_ln_s='cp -p' + else + as_ln_s='ln -s' + fi +elif ln conf$$.file conf$$ 2>/dev/null; then + as_ln_s=ln +else + as_ln_s='cp -p' +fi +rm -f conf$$ conf$$.exe conf$$.file + +if mkdir -p . 2>/dev/null; then + as_mkdir_p=: +else + test -d ./-p && rmdir ./-p + as_mkdir_p=false +fi + +as_executable_p="test -f" + +# Sed expression to map a string onto a valid CPP name. +as_tr_cpp="eval sed 'y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g'" + +# Sed expression to map a string onto a valid variable name. +as_tr_sh="eval sed 'y%*+%pp%;s%[^_$as_cr_alnum]%_%g'" + + +# IFS +# We need space, tab and new line, in precisely that order. +as_nl=' +' +IFS=" $as_nl" + +# CDPATH. +$as_unset CDPATH + +exec 6>&1 + +# Open the log real soon, to keep \$[0] and so on meaningful, and to +# report actual input values of CONFIG_FILES etc. instead of their +# values after options handling. Logging --version etc. is OK. +exec 5>>config.log +{ + echo + sed 'h;s/./-/g;s/^.../## /;s/...$/ ##/;p;x;p;x' <<_ASBOX +## Running $as_me. ## +_ASBOX +} >&5 +cat >&5 <<_CSEOF + +This file was extended by $as_me, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +config_files=" Makefile demo/Makefile g2_perl/Makefile.PL" + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + +Configuration files: +$config_files + +Report bugs to ." +ac_cs_version="\ +config.status +configured by ./configure, generated by GNU Autoconf 2.59, + with options \"'--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.'\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=. +INSTALL="/usr/bin/install -c" +# If no file are specified by the user, then we need to provide default +# value. By we need to know if files were specified by the user. +ac_need_defaults=: +while test $# != 0 +do + case $1 in + --*=*) + ac_option=`expr "x$1" : 'x\([^=]*\)='` + ac_optarg=`expr "x$1" : 'x[^=]*=\(.*\)'` + ac_shift=: + ;; + -*) + ac_option=$1 + ac_optarg=$2 + ac_shift=shift + ;; + *) # This is not an option, so the user has probably given explicit + # arguments. + ac_option=$1 + ac_need_defaults=false;; + esac + + case $ac_option in + # Handling of the options. + -recheck | --recheck | --rechec | --reche | --rech | --rec | --re | --r) + ac_cs_recheck=: ;; + --version | --vers* | -V ) + echo "$ac_cs_version"; exit 0 ;; + --he | --h) + # Conflict between --help and --header + { { echo "$as_me:$LINENO: error: ambiguous option: $1 +Try \`$0 --help' for more information." >&5 +echo "$as_me: error: ambiguous option: $1 +Try \`$0 --help' for more information." >&2;} + { (exit 1); exit 1; }; };; + --help | --hel | -h ) + echo "$ac_cs_usage"; exit 0 ;; + --debug | --d* | -d ) + debug=: ;; + --file | --fil | --fi | --f ) + $ac_shift + CONFIG_FILES="$CONFIG_FILES $ac_optarg" + ac_need_defaults=false;; + --header | --heade | --head | --hea ) + $ac_shift + CONFIG_HEADERS="$CONFIG_HEADERS $ac_optarg" + ac_need_defaults=false;; + -q | -quiet | --quiet | --quie | --qui | --qu | --q \ + | -silent | --silent | --silen | --sile | --sil | --si | --s) + ac_cs_silent=: ;; + + # This is an error. + -*) { { echo "$as_me:$LINENO: error: unrecognized option: $1 +Try \`$0 --help' for more information." >&5 +echo "$as_me: error: unrecognized option: $1 +Try \`$0 --help' for more information." >&2;} + { (exit 1); exit 1; }; } ;; + + *) ac_config_targets="$ac_config_targets $1" ;; + + esac + shift +done + +ac_configure_extra_args= + +if $ac_cs_silent; then + exec 6>/dev/null + ac_configure_extra_args="$ac_configure_extra_args --silent" +fi + +if $ac_cs_recheck; then + echo "running /bin/sh ./configure " '--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.' $ac_configure_extra_args " --no-create --no-recursion" >&6 + exec /bin/sh ./configure '--prefix=/usr/local' '--cache-file=/dev/null' '--srcdir=.' $ac_configure_extra_args --no-create --no-recursion +fi + +for ac_config_target in $ac_config_targets +do + case "$ac_config_target" in + # Handling of arguments. + "Makefile" ) CONFIG_FILES="$CONFIG_FILES Makefile" ;; + "demo/Makefile" ) CONFIG_FILES="$CONFIG_FILES demo/Makefile" ;; + "g2_perl/Makefile.PL" ) CONFIG_FILES="$CONFIG_FILES g2_perl/Makefile.PL" ;; + *) { { echo "$as_me:$LINENO: error: invalid argument: $ac_config_target" >&5 +echo "$as_me: error: invalid argument: $ac_config_target" >&2;} + { (exit 1); exit 1; }; };; + esac +done + +# If the user did not use the arguments to specify the items to instantiate, +# then the envvar interface is used. Set only those that are not. +# We use the long form for the default assignment because of an extremely +# bizarre bug on SunOS 4.1.3. +if $ac_need_defaults; then + test "${CONFIG_FILES+set}" = set || CONFIG_FILES=$config_files +fi + +# Have a temporary directory for convenience. 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It does not imply ALL GNU software can. +# +# This file is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2 of the License, or +# (at your option) any later version. +# +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the +# GNU General Public License for more details. +# +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, +# Boston, MA 02111-1307, USA. + +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Please send patches to . Submit a context +# diff and a properly formatted ChangeLog entry. +# +# Configuration subroutine to validate and canonicalize a configuration type. +# Supply the specified configuration type as an argument. +# If it is invalid, we print an error message on stderr and exit with code 1. +# Otherwise, we print the canonical config type on stdout and succeed. + +# This file is supposed to be the same for all GNU packages +# and recognize all the CPU types, system types and aliases +# that are meaningful with *any* GNU software. +# Each package is responsible for reporting which valid configurations +# it does not support. The user should be able to distinguish +# a failure to support a valid configuration from a meaningless +# configuration. + +# The goal of this file is to map all the various variations of a given +# machine specification into a single specification in the form: +# CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM +# or in some cases, the newer four-part form: +# CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM +# It is wrong to echo any other type of specification. + +me=`echo "$0" | sed -e 's,.*/,,'` + +usage="\ +Usage: $0 [OPTION] CPU-MFR-OPSYS + $0 [OPTION] ALIAS + +Canonicalize a configuration name. + +Operation modes: + -h, --help print this help, then exit + -t, --time-stamp print date of last modification, then exit + -v, --version print version number, then exit + +Report bugs and patches to ." + +version="\ +GNU config.sub ($timestamp) + +Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004 +Free Software Foundation, Inc. + +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE." + +help=" +Try \`$me --help' for more information." + +# Parse command line +while test $# -gt 0 ; do + case $1 in + --time-stamp | --time* | -t ) + echo "$timestamp" ; exit 0 ;; + --version | -v ) + echo "$version" ; exit 0 ;; + --help | --h* | -h ) + echo "$usage"; exit 0 ;; + -- ) # Stop option processing + shift; break ;; + - ) # Use stdin as input. + break ;; + -* ) + echo "$me: invalid option $1$help" + exit 1 ;; + + *local*) + # First pass through any local machine types. + echo $1 + exit 0;; + + * ) + break ;; + esac +done + +case $# in + 0) echo "$me: missing argument$help" >&2 + exit 1;; + 1) ;; + *) echo "$me: too many arguments$help" >&2 + exit 1;; +esac + +# Separate what the user gave into CPU-COMPANY and OS or KERNEL-OS (if any). +# Here we must recognize all the valid KERNEL-OS combinations. +maybe_os=`echo $1 | sed 's/^\(.*\)-\([^-]*-[^-]*\)$/\2/'` +case $maybe_os in + nto-qnx* | linux-gnu* | linux-dietlibc | linux-uclibc* | uclinux-uclibc* | uclinux-gnu* | \ + kfreebsd*-gnu* | knetbsd*-gnu* | netbsd*-gnu* | storm-chaos* | os2-emx* | rtmk-nova*) + os=-$maybe_os + basic_machine=`echo $1 | sed 's/^\(.*\)-\([^-]*-[^-]*\)$/\1/'` + ;; + *) + basic_machine=`echo $1 | sed 's/-[^-]*$//'` + if [ $basic_machine != $1 ] + then os=`echo $1 | sed 's/.*-/-/'` + else os=; fi + ;; +esac + +### Let's recognize common machines as not being operating systems so +### that things like config.sub decstation-3100 work. We also +### recognize some manufacturers as not being operating systems, so we +### can provide default operating systems below. +case $os in + -sun*os*) + # Prevent following clause from handling this invalid input. + ;; + -dec* | -mips* | -sequent* | -encore* | -pc532* | -sgi* | -sony* | \ + -att* | -7300* | -3300* | -delta* | -motorola* | -sun[234]* | \ + -unicom* | -ibm* | -next | -hp | -isi* | -apollo | -altos* | \ + -convergent* | -ncr* | -news | -32* | -3600* | -3100* | -hitachi* |\ + -c[123]* | -convex* | -sun | -crds | -omron* | -dg | -ultra | -tti* | \ + -harris | -dolphin | -highlevel | -gould | -cbm | -ns | -masscomp | \ + -apple | -axis | -knuth | -cray) + os= + basic_machine=$1 + ;; + -sim | -cisco | -oki | -wec | -winbond) + os= + basic_machine=$1 + ;; + -scout) + ;; + -wrs) + os=-vxworks + basic_machine=$1 + ;; + -chorusos*) + os=-chorusos + basic_machine=$1 + ;; + -chorusrdb) + os=-chorusrdb + basic_machine=$1 + ;; + -hiux*) + os=-hiuxwe2 + ;; + -sco5) + os=-sco3.2v5 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco4) + os=-sco3.2v4 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco3.2.[4-9]*) + os=`echo $os | sed -e 's/sco3.2./sco3.2v/'` + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco3.2v[4-9]*) + # Don't forget version if it is 3.2v4 or newer. + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco*) + os=-sco3.2v2 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -udk*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -isc) + os=-isc2.2 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -clix*) + basic_machine=clipper-intergraph + ;; + -isc*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -lynx*) + os=-lynxos + ;; + -ptx*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-sequent/'` + ;; + -windowsnt*) + os=`echo $os | sed -e 's/windowsnt/winnt/'` + ;; + -psos*) + os=-psos + ;; + -mint | -mint[0-9]*) + basic_machine=m68k-atari + os=-mint + ;; +esac + +# Decode aliases for certain CPU-COMPANY combinations. +case $basic_machine in + # Recognize the basic CPU types without company name. + # Some are omitted here because they have special meanings below. + 1750a | 580 \ + | a29k \ + | alpha | alphaev[4-8] | alphaev56 | alphaev6[78] | alphapca5[67] \ + | alpha64 | alpha64ev[4-8] | alpha64ev56 | alpha64ev6[78] | alpha64pca5[67] \ + | am33_2.0 \ + | arc | arm | arm[bl]e | arme[lb] | armv[2345] | armv[345][lb] | avr \ + | c4x | clipper \ + | d10v | d30v | dlx | dsp16xx \ + | fr30 | frv \ + | h8300 | h8500 | hppa | hppa1.[01] | hppa2.0 | hppa2.0[nw] | hppa64 \ + | i370 | i860 | i960 | ia64 \ + | ip2k | iq2000 \ + | m32r | m32rle | m68000 | m68k | m88k | mcore \ + | mips | mipsbe | mipseb | mipsel | mipsle \ + | mips16 \ + | mips64 | mips64el \ + | mips64vr | mips64vrel \ + | mips64orion | mips64orionel \ + | mips64vr4100 | mips64vr4100el \ + | mips64vr4300 | mips64vr4300el \ + | mips64vr5000 | mips64vr5000el \ + | mipsisa32 | mipsisa32el \ + | mipsisa32r2 | mipsisa32r2el \ + | mipsisa64 | mipsisa64el \ + | mipsisa64r2 | mipsisa64r2el \ + | mipsisa64sb1 | mipsisa64sb1el \ + | mipsisa64sr71k | mipsisa64sr71kel \ + | mipstx39 | mipstx39el \ + | mn10200 | mn10300 \ + | msp430 \ + | ns16k | ns32k \ + | openrisc | or32 \ + | pdp10 | pdp11 | pj | pjl \ + | powerpc | powerpc64 | powerpc64le | powerpcle | ppcbe \ + | pyramid \ + | sh | sh[1234] | sh[23]e | sh[34]eb | shbe | shle | sh[1234]le | sh3ele \ + | sh64 | sh64le \ + | sparc | sparc64 | sparc86x | sparclet | sparclite | sparcv8 | sparcv9 | sparcv9b \ + | strongarm \ + | tahoe | thumb | tic4x | tic80 | tron \ + | v850 | v850e \ + | we32k \ + | x86 | xscale | xstormy16 | xtensa \ + | z8k) + basic_machine=$basic_machine-unknown + ;; + m6811 | m68hc11 | m6812 | m68hc12) + # Motorola 68HC11/12. + basic_machine=$basic_machine-unknown + os=-none + ;; + m88110 | m680[12346]0 | m683?2 | m68360 | m5200 | v70 | w65 | z8k) + ;; + + # We use `pc' rather than `unknown' + # because (1) that's what they normally are, and + # (2) the word "unknown" tends to confuse beginning users. + i*86 | x86_64) + basic_machine=$basic_machine-pc + ;; + # Object if more than one company name word. + *-*-*) + echo Invalid configuration \`$1\': machine \`$basic_machine\' not recognized 1>&2 + exit 1 + ;; + # Recognize the basic CPU types with company name. + 580-* \ + | a29k-* \ + | alpha-* | alphaev[4-8]-* | alphaev56-* | alphaev6[78]-* \ + | alpha64-* | alpha64ev[4-8]-* | alpha64ev56-* | alpha64ev6[78]-* \ + | alphapca5[67]-* | alpha64pca5[67]-* | arc-* \ + | arm-* | armbe-* | armle-* | armeb-* | armv*-* \ + | avr-* \ + | bs2000-* \ + | c[123]* | c30-* | [cjt]90-* | c4x-* | c54x-* | c55x-* | c6x-* \ + | clipper-* | craynv-* | cydra-* \ + | d10v-* | d30v-* | dlx-* \ + | elxsi-* \ + | f30[01]-* | f700-* | fr30-* | frv-* | fx80-* \ + | h8300-* | h8500-* \ + | hppa-* | hppa1.[01]-* | hppa2.0-* | hppa2.0[nw]-* | hppa64-* \ + | i*86-* | i860-* | i960-* | ia64-* \ + | ip2k-* | iq2000-* \ + | m32r-* | m32rle-* \ + | m68000-* | m680[012346]0-* | m68360-* | m683?2-* | m68k-* \ + | m88110-* | m88k-* | mcore-* \ + | mips-* | mipsbe-* | mipseb-* | mipsel-* | mipsle-* \ + | mips16-* \ + | mips64-* | mips64el-* \ + | mips64vr-* | mips64vrel-* \ + | mips64orion-* | mips64orionel-* \ + | mips64vr4100-* | mips64vr4100el-* \ + | mips64vr4300-* | mips64vr4300el-* \ + | mips64vr5000-* | mips64vr5000el-* \ + | mipsisa32-* | mipsisa32el-* \ + | mipsisa32r2-* | mipsisa32r2el-* \ + | mipsisa64-* | mipsisa64el-* \ + | mipsisa64r2-* | mipsisa64r2el-* \ + | mipsisa64sb1-* | mipsisa64sb1el-* \ + | mipsisa64sr71k-* | mipsisa64sr71kel-* \ + | mipstx39-* | mipstx39el-* \ + | mmix-* \ + | msp430-* \ + | none-* | np1-* | ns16k-* | ns32k-* \ + | orion-* \ + | pdp10-* | pdp11-* | pj-* | pjl-* | pn-* | power-* \ + | powerpc-* | powerpc64-* | powerpc64le-* | powerpcle-* | ppcbe-* \ + | pyramid-* \ + | romp-* | rs6000-* \ + | sh-* | sh[1234]-* | sh[23]e-* | sh[34]eb-* | shbe-* \ + | shle-* | sh[1234]le-* | sh3ele-* | sh64-* | sh64le-* \ + | sparc-* | sparc64-* | sparc86x-* | sparclet-* | sparclite-* \ + | sparcv8-* | sparcv9-* | sparcv9b-* | strongarm-* | sv1-* | sx?-* \ + | tahoe-* | thumb-* \ + | tic30-* | tic4x-* | tic54x-* | tic55x-* | tic6x-* | tic80-* \ + | tron-* \ + | v850-* | v850e-* | vax-* \ + | we32k-* \ + | x86-* | x86_64-* | xps100-* | xscale-* | xstormy16-* \ + | xtensa-* \ + | ymp-* \ + | z8k-*) + ;; + # Recognize the various machine names and aliases which stand + # for a CPU type and a company and sometimes even an OS. + 386bsd) + basic_machine=i386-unknown + os=-bsd + ;; + 3b1 | 7300 | 7300-att | att-7300 | pc7300 | safari | unixpc) + basic_machine=m68000-att + ;; + 3b*) + basic_machine=we32k-att + ;; + a29khif) + basic_machine=a29k-amd + os=-udi + ;; + abacus) + basic_machine=abacus-unknown + ;; + adobe68k) + basic_machine=m68010-adobe + os=-scout + ;; + alliant | fx80) + basic_machine=fx80-alliant + ;; + altos | altos3068) + basic_machine=m68k-altos + ;; + am29k) + basic_machine=a29k-none + os=-bsd + ;; + amd64) + basic_machine=x86_64-pc + ;; + amd64-*) + basic_machine=x86_64-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + amdahl) + basic_machine=580-amdahl + os=-sysv + ;; + amiga | amiga-*) + basic_machine=m68k-unknown + ;; + amigaos | amigados) + basic_machine=m68k-unknown + os=-amigaos + ;; + amigaunix | amix) + basic_machine=m68k-unknown + os=-sysv4 + ;; + apollo68) + basic_machine=m68k-apollo + os=-sysv + ;; + apollo68bsd) + basic_machine=m68k-apollo + os=-bsd + ;; + aux) + basic_machine=m68k-apple + os=-aux + ;; + balance) + basic_machine=ns32k-sequent + os=-dynix + ;; + c90) + basic_machine=c90-cray + os=-unicos + ;; + convex-c1) + basic_machine=c1-convex + os=-bsd + ;; + convex-c2) + basic_machine=c2-convex + os=-bsd + ;; + convex-c32) + basic_machine=c32-convex + os=-bsd + ;; + convex-c34) + basic_machine=c34-convex + os=-bsd + ;; + convex-c38) + basic_machine=c38-convex + os=-bsd + ;; + cray | j90) + basic_machine=j90-cray + os=-unicos + ;; + craynv) + basic_machine=craynv-cray + os=-unicosmp + ;; + cr16c) + basic_machine=cr16c-unknown + os=-elf + ;; + crds | unos) + basic_machine=m68k-crds + ;; + cris | cris-* | etrax*) + basic_machine=cris-axis + ;; + crx) + basic_machine=crx-unknown + os=-elf + ;; + da30 | da30-*) + basic_machine=m68k-da30 + ;; + decstation | decstation-3100 | pmax | pmax-* | pmin | dec3100 | decstatn) + basic_machine=mips-dec + ;; + decsystem10* | dec10*) + basic_machine=pdp10-dec + os=-tops10 + ;; + decsystem20* | dec20*) + basic_machine=pdp10-dec + os=-tops20 + ;; + delta | 3300 | motorola-3300 | motorola-delta \ + | 3300-motorola | delta-motorola) + basic_machine=m68k-motorola + ;; + delta88) + basic_machine=m88k-motorola + os=-sysv3 + ;; + dpx20 | dpx20-*) + basic_machine=rs6000-bull + os=-bosx + ;; + dpx2* | dpx2*-bull) + basic_machine=m68k-bull + os=-sysv3 + ;; + ebmon29k) + basic_machine=a29k-amd + os=-ebmon + ;; + elxsi) + basic_machine=elxsi-elxsi + os=-bsd + ;; + encore | umax | mmax) + basic_machine=ns32k-encore + ;; + es1800 | OSE68k | ose68k | ose | OSE) + basic_machine=m68k-ericsson + os=-ose + ;; + fx2800) + basic_machine=i860-alliant + ;; + genix) + basic_machine=ns32k-ns + ;; + gmicro) + basic_machine=tron-gmicro + os=-sysv + ;; + go32) + basic_machine=i386-pc + os=-go32 + ;; + h3050r* | hiux*) + basic_machine=hppa1.1-hitachi + os=-hiuxwe2 + ;; + h8300hms) + basic_machine=h8300-hitachi + os=-hms + ;; + h8300xray) + basic_machine=h8300-hitachi + os=-xray + ;; + h8500hms) + basic_machine=h8500-hitachi + os=-hms + ;; + harris) + basic_machine=m88k-harris + os=-sysv3 + ;; + hp300-*) + basic_machine=m68k-hp + ;; + hp300bsd) + basic_machine=m68k-hp + os=-bsd + ;; + hp300hpux) + basic_machine=m68k-hp + os=-hpux + ;; + hp3k9[0-9][0-9] | hp9[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hp9k2[0-9][0-9] | hp9k31[0-9]) + basic_machine=m68000-hp + ;; + hp9k3[2-9][0-9]) + basic_machine=m68k-hp + ;; + hp9k6[0-9][0-9] | hp6[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hp9k7[0-79][0-9] | hp7[0-79][0-9]) + basic_machine=hppa1.1-hp + ;; + hp9k78[0-9] | hp78[0-9]) + # FIXME: really hppa2.0-hp + basic_machine=hppa1.1-hp + ;; + hp9k8[67]1 | hp8[67]1 | hp9k80[24] | hp80[24] | hp9k8[78]9 | hp8[78]9 | hp9k893 | hp893) + # FIXME: really hppa2.0-hp + basic_machine=hppa1.1-hp + ;; + hp9k8[0-9][13679] | hp8[0-9][13679]) + basic_machine=hppa1.1-hp + ;; + hp9k8[0-9][0-9] | hp8[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hppa-next) + os=-nextstep3 + ;; + hppaosf) + basic_machine=hppa1.1-hp + os=-osf + ;; + hppro) + basic_machine=hppa1.1-hp + os=-proelf + ;; + i370-ibm* | ibm*) + basic_machine=i370-ibm + ;; +# I'm not sure what "Sysv32" means. Should this be sysv3.2? + i*86v32) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv32 + ;; + i*86v4*) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv4 + ;; + i*86v) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv + ;; + i*86sol2) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-solaris2 + ;; + i386mach) + basic_machine=i386-mach + os=-mach + ;; + i386-vsta | vsta) + basic_machine=i386-unknown + os=-vsta + ;; + iris | iris4d) + basic_machine=mips-sgi + case $os in + -irix*) + ;; + *) + os=-irix4 + ;; + esac + ;; + isi68 | isi) + basic_machine=m68k-isi + os=-sysv + ;; + m88k-omron*) + basic_machine=m88k-omron + ;; + magnum | m3230) + basic_machine=mips-mips + os=-sysv + ;; + merlin) + basic_machine=ns32k-utek + os=-sysv + ;; + mingw32) + basic_machine=i386-pc + os=-mingw32 + ;; + miniframe) + basic_machine=m68000-convergent + ;; + *mint | -mint[0-9]* | *MiNT | *MiNT[0-9]*) + basic_machine=m68k-atari + os=-mint + ;; + mips3*-*) + basic_machine=`echo $basic_machine | sed -e 's/mips3/mips64/'` + ;; + mips3*) + basic_machine=`echo $basic_machine | sed -e 's/mips3/mips64/'`-unknown + ;; + monitor) + basic_machine=m68k-rom68k + os=-coff + ;; + morphos) + basic_machine=powerpc-unknown + os=-morphos + ;; + msdos) + basic_machine=i386-pc + os=-msdos + ;; + mvs) + basic_machine=i370-ibm + os=-mvs + ;; + ncr3000) + basic_machine=i486-ncr + os=-sysv4 + ;; + netbsd386) + basic_machine=i386-unknown + os=-netbsd + ;; + netwinder) + basic_machine=armv4l-rebel + os=-linux + ;; + news | news700 | news800 | news900) + basic_machine=m68k-sony + os=-newsos + ;; + news1000) + basic_machine=m68030-sony + os=-newsos + ;; + news-3600 | risc-news) + basic_machine=mips-sony + os=-newsos + ;; + necv70) + basic_machine=v70-nec + os=-sysv + ;; + next | m*-next ) + basic_machine=m68k-next + case $os in + -nextstep* ) + ;; + -ns2*) + os=-nextstep2 + ;; + *) + os=-nextstep3 + ;; + esac + ;; + nh3000) + basic_machine=m68k-harris + os=-cxux + ;; + nh[45]000) + basic_machine=m88k-harris + os=-cxux + ;; + nindy960) + basic_machine=i960-intel + os=-nindy + ;; + mon960) + basic_machine=i960-intel + os=-mon960 + ;; + nonstopux) + basic_machine=mips-compaq + os=-nonstopux + ;; + np1) + basic_machine=np1-gould + ;; + nsr-tandem) + basic_machine=nsr-tandem + ;; + op50n-* | op60c-*) + basic_machine=hppa1.1-oki + os=-proelf + ;; + or32 | or32-*) + basic_machine=or32-unknown + os=-coff + ;; + os400) + basic_machine=powerpc-ibm + os=-os400 + ;; + OSE68000 | ose68000) + basic_machine=m68000-ericsson + os=-ose + ;; + os68k) + basic_machine=m68k-none + os=-os68k + ;; + pa-hitachi) + basic_machine=hppa1.1-hitachi + os=-hiuxwe2 + ;; + paragon) + basic_machine=i860-intel + os=-osf + ;; + pbd) + basic_machine=sparc-tti + ;; + pbb) + basic_machine=m68k-tti + ;; + pc532 | pc532-*) + basic_machine=ns32k-pc532 + ;; + pentium | p5 | k5 | k6 | nexgen | viac3) + basic_machine=i586-pc + ;; + pentiumpro | p6 | 6x86 | athlon | athlon_*) + basic_machine=i686-pc + ;; + pentiumii | pentium2 | pentiumiii | pentium3) + basic_machine=i686-pc + ;; + pentium4) + basic_machine=i786-pc + ;; + pentium-* | p5-* | k5-* | k6-* | nexgen-* | viac3-*) + basic_machine=i586-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentiumpro-* | p6-* | 6x86-* | athlon-*) + basic_machine=i686-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentiumii-* | pentium2-* | pentiumiii-* | pentium3-*) + basic_machine=i686-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentium4-*) + basic_machine=i786-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pn) + basic_machine=pn-gould + ;; + power) basic_machine=power-ibm + ;; + ppc) basic_machine=powerpc-unknown + ;; + ppc-*) basic_machine=powerpc-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppcle | powerpclittle | ppc-le | powerpc-little) + basic_machine=powerpcle-unknown + ;; + ppcle-* | powerpclittle-*) + basic_machine=powerpcle-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppc64) basic_machine=powerpc64-unknown + ;; + ppc64-*) basic_machine=powerpc64-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppc64le | powerpc64little | ppc64-le | powerpc64-little) + basic_machine=powerpc64le-unknown + ;; + ppc64le-* | powerpc64little-*) + basic_machine=powerpc64le-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ps2) + basic_machine=i386-ibm + ;; + pw32) + basic_machine=i586-unknown + os=-pw32 + ;; + rom68k) + basic_machine=m68k-rom68k + os=-coff + ;; + rm[46]00) + basic_machine=mips-siemens + ;; + rtpc | rtpc-*) + basic_machine=romp-ibm + ;; + s390 | s390-*) + basic_machine=s390-ibm + ;; + s390x | s390x-*) + basic_machine=s390x-ibm + ;; + sa29200) + basic_machine=a29k-amd + os=-udi + ;; + sb1) + basic_machine=mipsisa64sb1-unknown + ;; + sb1el) + basic_machine=mipsisa64sb1el-unknown + ;; + sei) + basic_machine=mips-sei + os=-seiux + ;; + sequent) + basic_machine=i386-sequent + ;; + sh) + basic_machine=sh-hitachi + os=-hms + ;; + sh64) + basic_machine=sh64-unknown + ;; + sparclite-wrs | simso-wrs) + basic_machine=sparclite-wrs + os=-vxworks + ;; + sps7) + basic_machine=m68k-bull + os=-sysv2 + ;; + spur) + basic_machine=spur-unknown + ;; + st2000) + basic_machine=m68k-tandem + ;; + stratus) + basic_machine=i860-stratus + os=-sysv4 + ;; + sun2) + basic_machine=m68000-sun + ;; + sun2os3) + basic_machine=m68000-sun + os=-sunos3 + ;; + sun2os4) + basic_machine=m68000-sun + os=-sunos4 + ;; + sun3os3) + basic_machine=m68k-sun + os=-sunos3 + ;; + sun3os4) + basic_machine=m68k-sun + os=-sunos4 + ;; + sun4os3) + basic_machine=sparc-sun + os=-sunos3 + ;; + sun4os4) + basic_machine=sparc-sun + os=-sunos4 + ;; + sun4sol2) + basic_machine=sparc-sun + os=-solaris2 + ;; + sun3 | sun3-*) + basic_machine=m68k-sun + ;; + sun4) + basic_machine=sparc-sun + ;; + sun386 | sun386i | roadrunner) + basic_machine=i386-sun + ;; + sv1) + basic_machine=sv1-cray + os=-unicos + ;; + symmetry) + basic_machine=i386-sequent + os=-dynix + ;; + t3e) + basic_machine=alphaev5-cray + os=-unicos + ;; + t90) + basic_machine=t90-cray + os=-unicos + ;; + tic54x | c54x*) + basic_machine=tic54x-unknown + os=-coff + ;; + tic55x | c55x*) + basic_machine=tic55x-unknown + os=-coff + ;; + tic6x | c6x*) + basic_machine=tic6x-unknown + os=-coff + ;; + tx39) + basic_machine=mipstx39-unknown + ;; + tx39el) + basic_machine=mipstx39el-unknown + ;; + toad1) + basic_machine=pdp10-xkl + os=-tops20 + ;; + tower | tower-32) + basic_machine=m68k-ncr + ;; + tpf) + basic_machine=s390x-ibm + os=-tpf + ;; + udi29k) + basic_machine=a29k-amd + os=-udi + ;; + ultra3) + basic_machine=a29k-nyu + os=-sym1 + ;; + v810 | necv810) + basic_machine=v810-nec + os=-none + ;; + vaxv) + basic_machine=vax-dec + os=-sysv + ;; + vms) + basic_machine=vax-dec + os=-vms + ;; + vpp*|vx|vx-*) + basic_machine=f301-fujitsu + ;; + vxworks960) + basic_machine=i960-wrs + os=-vxworks + ;; + vxworks68) + basic_machine=m68k-wrs + os=-vxworks + ;; + vxworks29k) + basic_machine=a29k-wrs + os=-vxworks + ;; + w65*) + basic_machine=w65-wdc + os=-none + ;; + w89k-*) + basic_machine=hppa1.1-winbond + os=-proelf + ;; + xps | xps100) + basic_machine=xps100-honeywell + ;; + ymp) + basic_machine=ymp-cray + os=-unicos + ;; + z8k-*-coff) + basic_machine=z8k-unknown + os=-sim + ;; + none) + basic_machine=none-none + os=-none + ;; + +# Here we handle the default manufacturer of certain CPU types. It is in +# some cases the only manufacturer, in others, it is the most popular. + w89k) + basic_machine=hppa1.1-winbond + ;; + op50n) + basic_machine=hppa1.1-oki + ;; + op60c) + basic_machine=hppa1.1-oki + ;; + romp) + basic_machine=romp-ibm + ;; + mmix) + basic_machine=mmix-knuth + ;; + rs6000) + basic_machine=rs6000-ibm + ;; + vax) + basic_machine=vax-dec + ;; + pdp10) + # there are many clones, so DEC is not a safe bet + basic_machine=pdp10-unknown + ;; + pdp11) + basic_machine=pdp11-dec + ;; + we32k) + basic_machine=we32k-att + ;; + sh3 | sh4 | sh[34]eb | sh[1234]le | sh[23]ele) + basic_machine=sh-unknown + ;; + sh64) + basic_machine=sh64-unknown + ;; + sparc | sparcv8 | sparcv9 | sparcv9b) + basic_machine=sparc-sun + ;; + cydra) + basic_machine=cydra-cydrome + ;; + orion) + basic_machine=orion-highlevel + ;; + orion105) + basic_machine=clipper-highlevel + ;; + mac | mpw | mac-mpw) + basic_machine=m68k-apple + ;; + pmac | pmac-mpw) + basic_machine=powerpc-apple + ;; + *-unknown) + # Make sure to match an already-canonicalized machine name. + ;; + *) + echo Invalid configuration \`$1\': machine \`$basic_machine\' not recognized 1>&2 + exit 1 + ;; +esac + +# Here we canonicalize certain aliases for manufacturers. +case $basic_machine in + *-digital*) + basic_machine=`echo $basic_machine | sed 's/digital.*/dec/'` + ;; + *-commodore*) + basic_machine=`echo $basic_machine | sed 's/commodore.*/cbm/'` + ;; + *) + ;; +esac + +# Decode manufacturer-specific aliases for certain operating systems. + +if [ x"$os" != x"" ] +then +case $os in + # First match some system type aliases + # that might get confused with valid system types. + # -solaris* is a basic system type, with this one exception. + -solaris1 | -solaris1.*) + os=`echo $os | sed -e 's|solaris1|sunos4|'` + ;; + -solaris) + os=-solaris2 + ;; + -svr4*) + os=-sysv4 + ;; + -unixware*) + os=-sysv4.2uw + ;; + -gnu/linux*) + os=`echo $os | sed -e 's|gnu/linux|linux-gnu|'` + ;; + # First accept the basic system types. + # The portable systems comes first. + # Each alternative MUST END IN A *, to match a version number. + # -sysv* is not here because it comes later, after sysvr4. + -gnu* | -bsd* | -mach* | -minix* | -genix* | -ultrix* | -irix* \ + | -*vms* | -sco* | -esix* | -isc* | -aix* | -sunos | -sunos[34]*\ + | -hpux* | -unos* | -osf* | -luna* | -dgux* | -solaris* | -sym* \ + | -amigaos* | -amigados* | -msdos* | -newsos* | -unicos* | -aof* \ + | -aos* \ + | -nindy* | -vxsim* | -vxworks* | -ebmon* | -hms* | -mvs* \ + | -clix* | -riscos* | -uniplus* | -iris* | -rtu* | -xenix* \ + | -hiux* | -386bsd* | -knetbsd* | -mirbsd* | -netbsd* | -openbsd* \ + | -ekkobsd* | -kfreebsd* | -freebsd* | -riscix* | -lynxos* \ + | -bosx* | -nextstep* | -cxux* | -aout* | -elf* | -oabi* \ + | -ptx* | -coff* | -ecoff* | -winnt* | -domain* | -vsta* \ + | -udi* | -eabi* | -lites* | -ieee* | -go32* | -aux* \ + | -chorusos* | -chorusrdb* \ + | -cygwin* | -pe* | -psos* | -moss* | -proelf* | -rtems* \ + | -mingw32* | -linux-gnu* | -linux-uclibc* | -uxpv* | -beos* | -mpeix* | -udk* \ + | -interix* | -uwin* | -mks* | -rhapsody* | -darwin* | -opened* \ + | -openstep* | -oskit* | -conix* | -pw32* | -nonstopux* \ + | -storm-chaos* | -tops10* | -tenex* | -tops20* | -its* \ + | -os2* | -vos* | -palmos* | -uclinux* | -nucleus* \ + | -morphos* | -superux* | -rtmk* | -rtmk-nova* | -windiss* \ + | -powermax* | -dnix* | -nx6 | -nx7 | -sei* | -dragonfly*) + # Remember, each alternative MUST END IN *, to match a version number. + ;; + -qnx*) + case $basic_machine in + x86-* | i*86-*) + ;; + *) + os=-nto$os + ;; + esac + ;; + -nto-qnx*) + ;; + -nto*) + os=`echo $os | sed -e 's|nto|nto-qnx|'` + ;; + -sim | -es1800* | -hms* | -xray | -os68k* | -none* | -v88r* \ + | -windows* | -osx | -abug | -netware* | -os9* | -beos* \ + | -macos* | -mpw* | -magic* | -mmixware* | -mon960* | -lnews*) + ;; + -mac*) + os=`echo $os | sed -e 's|mac|macos|'` + ;; + -linux-dietlibc) + os=-linux-dietlibc + ;; + -linux*) + os=`echo $os | sed -e 's|linux|linux-gnu|'` + ;; + -sunos5*) + os=`echo $os | sed -e 's|sunos5|solaris2|'` + ;; + -sunos6*) + os=`echo $os | sed -e 's|sunos6|solaris3|'` + ;; + -opened*) + os=-openedition + ;; + -os400*) + os=-os400 + ;; + -wince*) + os=-wince + ;; + -osfrose*) + os=-osfrose + ;; + -osf*) + os=-osf + ;; + -utek*) + os=-bsd + ;; + -dynix*) + os=-bsd + ;; + -acis*) + os=-aos + ;; + -atheos*) + os=-atheos + ;; + -syllable*) + os=-syllable + ;; + -386bsd) + os=-bsd + ;; + -ctix* | -uts*) + os=-sysv + ;; + -nova*) + os=-rtmk-nova + ;; + -ns2 ) + os=-nextstep2 + ;; + -nsk*) + os=-nsk + ;; + # Preserve the version number of sinix5. + -sinix5.*) + os=`echo $os | sed -e 's|sinix|sysv|'` + ;; + -sinix*) + os=-sysv4 + ;; + -tpf*) + os=-tpf + ;; + -triton*) + os=-sysv3 + ;; + -oss*) + os=-sysv3 + ;; + -svr4) + os=-sysv4 + ;; + -svr3) + os=-sysv3 + ;; + -sysvr4) + os=-sysv4 + ;; + # This must come after -sysvr4. + -sysv*) + ;; + -ose*) + os=-ose + ;; + -es1800*) + os=-ose + ;; + -xenix) + os=-xenix + ;; + -*mint | -mint[0-9]* | -*MiNT | -MiNT[0-9]*) + os=-mint + ;; + -aros*) + os=-aros + ;; + -kaos*) + os=-kaos + ;; + -none) + ;; + *) + # Get rid of the `-' at the beginning of $os. + os=`echo $os | sed 's/[^-]*-//'` + echo Invalid configuration \`$1\': system \`$os\' not recognized 1>&2 + exit 1 + ;; +esac +else + +# Here we handle the default operating systems that come with various machines. +# The value should be what the vendor currently ships out the door with their +# machine or put another way, the most popular os provided with the machine. + +# Note that if you're going to try to match "-MANUFACTURER" here (say, +# "-sun"), then you have to tell the case statement up towards the top +# that MANUFACTURER isn't an operating system. Otherwise, code above +# will signal an error saying that MANUFACTURER isn't an operating +# system, and we'll never get to this point. + +case $basic_machine in + *-acorn) + os=-riscix1.2 + ;; + arm*-rebel) + os=-linux + ;; + arm*-semi) + os=-aout + ;; + c4x-* | tic4x-*) + os=-coff + ;; + # This must come before the *-dec entry. + pdp10-*) + os=-tops20 + ;; + pdp11-*) + os=-none + ;; + *-dec | vax-*) + os=-ultrix4.2 + ;; + m68*-apollo) + os=-domain + ;; + i386-sun) + os=-sunos4.0.2 + ;; + m68000-sun) + os=-sunos3 + # This also exists in the configure program, but was not the + # default. + # os=-sunos4 + ;; + m68*-cisco) + os=-aout + ;; + mips*-cisco) + os=-elf + ;; + mips*-*) + os=-elf + ;; + or32-*) + os=-coff + ;; + *-tti) # must be before sparc entry or we get the wrong os. + os=-sysv3 + ;; + sparc-* | *-sun) + os=-sunos4.1.1 + ;; + *-be) + os=-beos + ;; + *-ibm) + os=-aix + ;; + *-knuth) + os=-mmixware + ;; + *-wec) + os=-proelf + ;; + *-winbond) + os=-proelf + ;; + *-oki) + os=-proelf + ;; + *-hp) + os=-hpux + ;; + *-hitachi) + os=-hiux + ;; + i860-* | *-att | *-ncr | *-altos | *-motorola | *-convergent) + os=-sysv + ;; + *-cbm) + os=-amigaos + ;; + *-dg) + os=-dgux + ;; + *-dolphin) + os=-sysv3 + ;; + m68k-ccur) + os=-rtu + ;; + m88k-omron*) + os=-luna + ;; + *-next ) + os=-nextstep + ;; + *-sequent) + os=-ptx + ;; + *-crds) + os=-unos + ;; + *-ns) + os=-genix + ;; + i370-*) + os=-mvs + ;; + *-next) + os=-nextstep3 + ;; + *-gould) + os=-sysv + ;; + *-highlevel) + os=-bsd + ;; + *-encore) + os=-bsd + ;; + *-sgi) + os=-irix + ;; + *-siemens) + os=-sysv4 + ;; + *-masscomp) + os=-rtu + ;; + f30[01]-fujitsu | f700-fujitsu) + os=-uxpv + ;; + *-rom68k) + os=-coff + ;; + *-*bug) + os=-coff + ;; + *-apple) + os=-macos + ;; + *-atari*) + os=-mint + ;; + *) + os=-none + ;; +esac +fi + +# Here we handle the case where we know the os, and the CPU type, but not the +# manufacturer. We pick the logical manufacturer. +vendor=unknown +case $basic_machine in + *-unknown) + case $os in + -riscix*) + vendor=acorn + ;; + -sunos*) + vendor=sun + ;; + -aix*) + vendor=ibm + ;; + -beos*) + vendor=be + ;; + -hpux*) + vendor=hp + ;; + -mpeix*) + vendor=hp + ;; + -hiux*) + vendor=hitachi + ;; + -unos*) + vendor=crds + ;; + -dgux*) + vendor=dg + ;; + -luna*) + vendor=omron + ;; + -genix*) + vendor=ns + ;; + -mvs* | -opened*) + vendor=ibm + ;; + -os400*) + vendor=ibm + ;; + -ptx*) + vendor=sequent + ;; + -tpf*) + vendor=ibm + ;; + -vxsim* | -vxworks* | -windiss*) + vendor=wrs + ;; + -aux*) + vendor=apple + ;; + -hms*) + vendor=hitachi + ;; + -mpw* | -macos*) + vendor=apple + ;; + -*mint | -mint[0-9]* | -*MiNT | -MiNT[0-9]*) + vendor=atari + ;; + -vos*) + vendor=stratus + ;; + esac + basic_machine=`echo $basic_machine | sed "s/unknown/$vendor/"` + ;; +esac + +echo $basic_machine$os +exit 0 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "timestamp='" +# time-stamp-format: "%:y-%02m-%02d" +# time-stamp-end: "'" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure new file mode 100755 index 00000000..fd4d1d5b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure @@ -0,0 +1,6602 @@ +#! /bin/sh +# Guess values for system-dependent variables and create Makefiles. +# Generated by GNU Autoconf 2.59. +# +# Copyright (C) 2003 Free Software Foundation, Inc. +# This configure script is free software; the Free Software Foundation +# gives unlimited permission to copy, distribute and modify it. +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2 + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. 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See below for descriptions of some of the useful variables. + +Defaults for the options are specified in brackets. + +Configuration: + -h, --help display this help and exit + --help=short display options specific to this package + --help=recursive display the short help of all the included packages + -V, --version display version information and exit + -q, --quiet, --silent do not print \`checking...' messages + --cache-file=FILE cache test results in FILE [disabled] + -C, --config-cache alias for \`--cache-file=config.cache' + -n, --no-create do not create output files + --srcdir=DIR find the sources in DIR [configure dir or \`..'] + +_ACEOF + + cat <<_ACEOF +Installation directories: + --prefix=PREFIX install architecture-independent files in PREFIX + [$ac_default_prefix] + --exec-prefix=EPREFIX install architecture-dependent files in EPREFIX + [PREFIX] + +By default, \`make install' will install all the files in +\`$ac_default_prefix/bin', \`$ac_default_prefix/lib' etc. You can specify +an installation prefix other than \`$ac_default_prefix' using \`--prefix', +for instance \`--prefix=\$HOME'. + +For better control, use the options below. + +Fine tuning of the installation directories: + --bindir=DIR user executables [EPREFIX/bin] + --sbindir=DIR system admin executables [EPREFIX/sbin] + --libexecdir=DIR program executables [EPREFIX/libexec] + --datadir=DIR read-only architecture-independent data [PREFIX/share] + --sysconfdir=DIR read-only single-machine data [PREFIX/etc] + --sharedstatedir=DIR modifiable architecture-independent data [PREFIX/com] + --localstatedir=DIR modifiable single-machine data [PREFIX/var] + --libdir=DIR object code libraries [EPREFIX/lib] + --includedir=DIR C header files [PREFIX/include] + --oldincludedir=DIR C header files for non-gcc [/usr/include] + --infodir=DIR info documentation [PREFIX/info] + --mandir=DIR man documentation [PREFIX/man] +_ACEOF + + cat <<\_ACEOF + +X features: + --x-includes=DIR X include files are in DIR + --x-libraries=DIR X library files are in DIR + +System types: + --build=BUILD configure for building on BUILD [guessed] + --host=HOST cross-compile to build programs to run on HOST [BUILD] +_ACEOF +fi + +if test -n "$ac_init_help"; then + + cat <<\_ACEOF + +Optional Packages: + --with-PACKAGE[=ARG] use PACKAGE [ARG=yes] + --without-PACKAGE do not use PACKAGE (same as --with-PACKAGE=no) + --with-x use the X Window System + +Some influential environment variables: + CC C compiler command + CFLAGS C compiler flags + LDFLAGS linker flags, e.g. -L if you have libraries in a + nonstandard directory + CPPFLAGS C/C++ preprocessor flags, e.g. -I if you have + headers in a nonstandard directory + CPP C preprocessor + CXX C++ compiler command + CXXFLAGS C++ compiler flags + +Use these variables to override the choices made by `configure' or to help +it to find libraries and programs with nonstandard names/locations. + +_ACEOF +fi + +if test "$ac_init_help" = "recursive"; then + # If there are subdirs, report their specific --help. + ac_popdir=`pwd` + for ac_dir in : $ac_subdirs_all; do test "x$ac_dir" = x: && continue + test -d $ac_dir || continue + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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"$ac_site_file" + fi +done + +if test -r "$cache_file"; then + # Some versions of bash will fail to source /dev/null (special + # files actually), so we avoid doing that. + if test -f "$cache_file"; then + { echo "$as_me:$LINENO: loading cache $cache_file" >&5 +echo "$as_me: loading cache $cache_file" >&6;} + case $cache_file in + [\\/]* | ?:[\\/]* ) . $cache_file;; + *) . ./$cache_file;; + esac + fi +else + { echo "$as_me:$LINENO: creating cache $cache_file" >&5 +echo "$as_me: creating cache $cache_file" >&6;} + >$cache_file +fi + +# Check that the precious variables saved in the cache have kept the same +# value. +ac_cache_corrupted=false +for ac_var in `(set) 2>&1 | + sed -n 's/^ac_env_\([a-zA-Z_0-9]*\)_set=.*/\1/p'`; do + eval ac_old_set=\$ac_cv_env_${ac_var}_set + eval ac_new_set=\$ac_env_${ac_var}_set + eval ac_old_val="\$ac_cv_env_${ac_var}_value" + eval ac_new_val="\$ac_env_${ac_var}_value" + case $ac_old_set,$ac_new_set in + set,) + { echo "$as_me:$LINENO: error: \`$ac_var' was set to \`$ac_old_val' in the previous run" >&5 +echo "$as_me: error: \`$ac_var' was set to \`$ac_old_val' in the previous run" >&2;} + ac_cache_corrupted=: ;; + ,set) + { echo "$as_me:$LINENO: error: \`$ac_var' was not set in the previous run" >&5 +echo "$as_me: error: \`$ac_var' was not set in the previous run" >&2;} + ac_cache_corrupted=: ;; + ,);; + *) + if test "x$ac_old_val" != "x$ac_new_val"; then + { echo "$as_me:$LINENO: error: \`$ac_var' has changed since the previous run:" >&5 +echo "$as_me: error: \`$ac_var' has changed since the previous run:" >&2;} + { echo "$as_me:$LINENO: former value: $ac_old_val" >&5 +echo "$as_me: former value: $ac_old_val" >&2;} + { echo "$as_me:$LINENO: current value: $ac_new_val" >&5 +echo "$as_me: current value: $ac_new_val" >&2;} + ac_cache_corrupted=: + fi;; + esac + # Pass precious variables to config.status. + if test "$ac_new_set" = set; then + case $ac_new_val in + *" "*|*" "*|*[\[\]\~\#\$\^\&\*\(\)\{\}\\\|\;\<\>\?\"\']*) + ac_arg=$ac_var=`echo "$ac_new_val" | sed "s/'/'\\\\\\\\''/g"` ;; + *) ac_arg=$ac_var=$ac_new_val ;; + esac + case " $ac_configure_args " in + *" '$ac_arg' "*) ;; # Avoid dups. 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then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install-sh -c" + break + elif test -f $ac_dir/install.sh; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/install.sh -c" + break + elif test -f $ac_dir/shtool; then + ac_aux_dir=$ac_dir + ac_install_sh="$ac_aux_dir/shtool install -c" + break + fi +done +if test -z "$ac_aux_dir"; then + { { echo "$as_me:$LINENO: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&5 +echo "$as_me: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&2;} + { (exit 1); exit 1; }; } +fi +ac_config_guess="$SHELL $ac_aux_dir/config.guess" +ac_config_sub="$SHELL $ac_aux_dir/config.sub" +ac_configure="$SHELL $ac_aux_dir/configure" # This should be Cygnus configure. + +# Make sure we can run config.sub. +$ac_config_sub sun4 >/dev/null 2>&1 || + { { echo "$as_me:$LINENO: error: cannot run $ac_config_sub" >&5 +echo "$as_me: error: cannot run $ac_config_sub" >&2;} + { (exit 1); exit 1; }; } + +echo "$as_me:$LINENO: checking build system type" >&5 +echo $ECHO_N "checking build system type... $ECHO_C" >&6 +if test "${ac_cv_build+set}" = set; 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then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_host_alias=$host_alias +test -z "$ac_cv_host_alias" && + ac_cv_host_alias=$ac_cv_build_alias +ac_cv_host=`$ac_config_sub $ac_cv_host_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_host_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_host_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_host" >&5 +echo "${ECHO_T}$ac_cv_host" >&6 +host=$ac_cv_host +host_cpu=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +host_vendor=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +host_os=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + +case "$host" in + *-linux*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared -soname libg2.so.0' + LD_SHARED_OPT='' + LD_SHARED_EXT='so.0.$(G2_VERSION)' + cat >>confdefs.h <<\_ACEOF +#define LINUX 1 +_ACEOF +;; + *-aix*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-bM:SRE -bnoentry -bexpall' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +#define AIX 1 +_ACEOF +;; + *-osf*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +#define OSF 1 +_ACEOF +;; + *) + LD_SHARED_EXT='so' + cat >>confdefs.h <<\_ACEOF +#define UNIX 1 +_ACEOF +;; +esac + + + + + + +# +# check C compiler, preprocesor, etc. +# +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args. +set dummy ${ac_tool_prefix}gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "gcc", so it can be a program name with args. +set dummy gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args. +set dummy ${ac_tool_prefix}cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +fi +if test -z "$CC"; then + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else + ac_prog_rejected=no +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then + ac_prog_rejected=yes + continue + fi + ac_cv_prog_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +if test $ac_prog_rejected = yes; then + # We found a bogon in the path, so make sure we never use it. + set dummy $ac_cv_prog_CC + shift + if test $# != 0; then + # We chose a different compiler from the bogus one. + # However, it has the same basename, so the bogon will be chosen + # first if we set CC to just the basename; use the full file name. + shift + ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@" + fi +fi +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + for ac_prog in cl + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CC" && break + done +fi +if test -z "$CC"; then + ac_ct_CC=$CC + for ac_prog in cl +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CC" && break +done + + CC=$ac_ct_CC +fi + +fi + + +test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&5 +echo "$as_me: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files a.out a.exe b.out" +# Try to create an executable without -o first, disregard a.out. +# It will help us diagnose broken compilers, and finding out an intuition +# of exeext. +echo "$as_me:$LINENO: checking for C compiler default output file name" >&5 +echo $ECHO_N "checking for C compiler default output file name... $ECHO_C" >&6 +ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'` +if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5 + (eval $ac_link_default) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # Find the output, starting from the most likely. This scheme is +# not robust to junk in `.', hence go to wildcards (a.*) only as a last +# resort. + +# Be careful to initialize this variable, since it used to be cached. +# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile. +ac_cv_exeext= +# b.out is created by i960 compilers. +for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out +do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) + ;; + conftest.$ac_ext ) + # This is the source file. + ;; + [ab].out ) + # We found the default executable, but exeext='' is most + # certainly right. + break;; + *.* ) + ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + # FIXME: I believe we export ac_cv_exeext for Libtool, + # but it would be cool to find out if it's true. Does anybody + # maintain Libtool? --akim. + export ac_cv_exeext + break;; + * ) + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: C compiler cannot create executables +See \`config.log' for more details." >&5 +echo "$as_me: error: C compiler cannot create executables +See \`config.log' for more details." >&2;} + { (exit 77); exit 77; }; } +fi + +ac_exeext=$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_file" >&5 +echo "${ECHO_T}$ac_file" >&6 + +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether the C compiler works" >&5 +echo $ECHO_N "checking whether the C compiler works... $ECHO_C" >&6 +# FIXME: These cross compiler hacks should be removed for Autoconf 3.0 +# If not cross compiling, check that we can run a simple program. +if test "$cross_compiling" != yes; then + if { ac_try='./$ac_file' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + cross_compiling=no + else + if test "$cross_compiling" = maybe; then + cross_compiling=yes + else + { { echo "$as_me:$LINENO: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + fi + fi +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +rm -f a.out a.exe conftest$ac_cv_exeext b.out +ac_clean_files=$ac_clean_files_save +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether we are cross compiling" >&5 +echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6 +echo "$as_me:$LINENO: result: $cross_compiling" >&5 +echo "${ECHO_T}$cross_compiling" >&6 + +echo "$as_me:$LINENO: checking for suffix of executables" >&5 +echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6 +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # If both `conftest.exe' and `conftest' are `present' (well, observable) +# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will +# work properly (i.e., refer to `conftest.exe'), while it won't with +# `rm'. +for ac_file in conftest.exe conftest conftest.*; do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;; + *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + export ac_cv_exeext + break;; + * ) break;; + esac +done +else + { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5 +echo "${ECHO_T}$ac_cv_exeext" >&6 + +rm -f conftest.$ac_ext +EXEEXT=$ac_cv_exeext +ac_exeext=$EXEEXT +echo "$as_me:$LINENO: checking for suffix of object files" >&5 +echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6 +if test "${ac_cv_objext+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.o conftest.obj +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;; + *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'` + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest.$ac_cv_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_objext" >&5 +echo "${ECHO_T}$ac_cv_objext" >&6 +OBJEXT=$ac_cv_objext +ac_objext=$OBJEXT +echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6 +if test "${ac_cv_c_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_c_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6 +GCC=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CFLAGS=${CFLAGS+set} +ac_save_CFLAGS=$CFLAGS +CFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5 +echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cc_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_g" >&6 +if test "$ac_test_CFLAGS" = set; then + CFLAGS=$ac_save_CFLAGS +elif test $ac_cv_prog_cc_g = yes; then + if test "$GCC" = yes; then + CFLAGS="-g -O2" + else + CFLAGS="-g" + fi +else + if test "$GCC" = yes; then + CFLAGS="-O2" + else + CFLAGS= + fi +fi +echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5 +echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_prog_cc_stdc=no +ac_save_CC=$CC +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include +/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */ +struct buf { int x; }; +FILE * (*rcsopen) (struct buf *, struct stat *, int); +static char *e (p, i) + char **p; + int i; +{ + return p[i]; +} +static char *f (char * (*g) (char **, int), char **p, ...) +{ + char *s; + va_list v; + va_start (v,p); + s = g (p, va_arg (v,int)); + va_end (v); + return s; +} + +/* OSF 4.0 Compaq cc is some sort of almost-ANSI by default. It has + function prototypes and stuff, but not '\xHH' hex character constants. + These don't provoke an error unfortunately, instead are silently treated + as 'x'. The following induces an error, until -std1 is added to get + proper ANSI mode. Curiously '\x00'!='x' always comes out true, for an + array size at least. It's necessary to write '\x00'==0 to get something + that's true only with -std1. */ +int osf4_cc_array ['\x00' == 0 ? 1 : -1]; + +int test (int i, double x); +struct s1 {int (*f) (int a);}; +struct s2 {int (*f) (double a);}; +int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int); +int argc; +char **argv; +int +main () +{ +return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1]; + ; + return 0; +} +_ACEOF +# Don't try gcc -ansi; that turns off useful extensions and +# breaks some systems' header files. +# AIX -qlanglvl=ansi +# Ultrix and OSF/1 -std1 +# HP-UX 10.20 and later -Ae +# HP-UX older versions -Aa -D_HPUX_SOURCE +# SVR4 -Xc -D__EXTENSIONS__ +for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__" +do + CC="$ac_save_CC $ac_arg" + rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_stdc=$ac_arg +break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext +done +rm -f conftest.$ac_ext conftest.$ac_objext +CC=$ac_save_CC + +fi + +case "x$ac_cv_prog_cc_stdc" in + x|xno) + echo "$as_me:$LINENO: result: none needed" >&5 +echo "${ECHO_T}none needed" >&6 ;; + *) + echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6 + CC="$CC $ac_cv_prog_cc_stdc" ;; +esac + +# Some people use a C++ compiler to compile C. Since we use `exit', +# in C++ we need to declare it. In case someone uses the same compiler +# for both compiling C and C++ we need to have the C++ compiler decide +# the declaration of exit, since it's the most demanding environment. +cat >conftest.$ac_ext <<_ACEOF +#ifndef __cplusplus + choke me +#endif +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +echo "$as_me:$LINENO: checking how to run the C preprocessor" >&5 +echo $ECHO_N "checking how to run the C preprocessor... $ECHO_C" >&6 +# On Suns, sometimes $CPP names a directory. +if test -n "$CPP" && test -d "$CPP"; then + CPP= +fi +if test -z "$CPP"; then + if test "${ac_cv_prog_CPP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # Double quotes because CPP needs to be expanded + for CPP in "$CC -E" "$CC -E -traditional-cpp" "/lib/cpp" + do + ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + break +fi + + done + ac_cv_prog_CPP=$CPP + +fi + CPP=$ac_cv_prog_CPP +else + ac_cv_prog_CPP=$CPP +fi +echo "$as_me:$LINENO: result: $CPP" >&5 +echo "${ECHO_T}$CPP" >&6 +ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + : +else + { { echo "$as_me:$LINENO: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&5 +echo "$as_me: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +ac_ext=cc +ac_cpp='$CXXCPP $CPPFLAGS' +ac_compile='$CXX -c $CXXFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CXX -o conftest$ac_exeext $CXXFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_cxx_compiler_gnu +if test -n "$ac_tool_prefix"; then + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CXX"; then + ac_cv_prog_CXX="$CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CXX="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CXX=$ac_cv_prog_CXX +if test -n "$CXX"; then + echo "$as_me:$LINENO: result: $CXX" >&5 +echo "${ECHO_T}$CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CXX" && break + done +fi +if test -z "$CXX"; then + ac_ct_CXX=$CXX + for ac_prog in $CCC g++ c++ gpp aCC CC cxx cc++ cl FCC KCC RCC xlC_r xlC +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CXX+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CXX"; then + ac_cv_prog_ac_ct_CXX="$ac_ct_CXX" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CXX="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CXX=$ac_cv_prog_ac_ct_CXX +if test -n "$ac_ct_CXX"; then + echo "$as_me:$LINENO: result: $ac_ct_CXX" >&5 +echo "${ECHO_T}$ac_ct_CXX" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CXX" && break +done +test -n "$ac_ct_CXX" || ac_ct_CXX="g++" + + CXX=$ac_ct_CXX +fi + + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C++ compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +echo "$as_me:$LINENO: checking whether we are using the GNU C++ compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C++ compiler... $ECHO_C" >&6 +if test "${ac_cv_cxx_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_cxx_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_cxx_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_cxx_compiler_gnu" >&6 +GXX=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CXXFLAGS=${CXXFLAGS+set} +ac_save_CXXFLAGS=$CXXFLAGS +CXXFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CXX accepts -g" >&5 +echo $ECHO_N "checking whether $CXX accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cxx_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cxx_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cxx_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cxx_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cxx_g" >&6 +if test "$ac_test_CXXFLAGS" = set; then + CXXFLAGS=$ac_save_CXXFLAGS +elif test $ac_cv_prog_cxx_g = yes; then + if test "$GXX" = yes; then + CXXFLAGS="-g -O2" + else + CXXFLAGS="-g" + fi +else + if test "$GXX" = yes; then + CXXFLAGS="-O2" + else + CXXFLAGS= + fi +fi +for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_cxx_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}ranlib", so it can be a program name with args. +set dummy ${ac_tool_prefix}ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$RANLIB"; then + ac_cv_prog_RANLIB="$RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_RANLIB="${ac_tool_prefix}ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +RANLIB=$ac_cv_prog_RANLIB +if test -n "$RANLIB"; then + echo "$as_me:$LINENO: result: $RANLIB" >&5 +echo "${ECHO_T}$RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_RANLIB"; then + ac_ct_RANLIB=$RANLIB + # Extract the first word of "ranlib", so it can be a program name with args. +set dummy ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_RANLIB"; then + ac_cv_prog_ac_ct_RANLIB="$ac_ct_RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_RANLIB="ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_RANLIB" && ac_cv_prog_ac_ct_RANLIB=":" +fi +fi +ac_ct_RANLIB=$ac_cv_prog_ac_ct_RANLIB +if test -n "$ac_ct_RANLIB"; then + echo "$as_me:$LINENO: result: $ac_ct_RANLIB" >&5 +echo "${ECHO_T}$ac_ct_RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + RANLIB=$ac_ct_RANLIB +else + RANLIB="$ac_cv_prog_RANLIB" +fi + +# Find a good install program. We prefer a C program (faster), +# so one script is as good as another. But avoid the broken or +# incompatible versions: +# SysV /etc/install, /usr/sbin/install +# SunOS /usr/etc/install +# IRIX /sbin/install +# AIX /bin/install +# AmigaOS /C/install, which installs bootblocks on floppy discs +# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag +# AFS /usr/afsws/bin/install, which mishandles nonexistent args +# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff" +# OS/2's system install, which has a completely different semantic +# ./install, which can be erroneously created by make from ./install.sh. +echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5 +echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6 +if test -z "$INSTALL"; then +if test "${ac_cv_path_install+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + # Account for people who put trailing slashes in PATH elements. +case $as_dir/ in + ./ | .// | /cC/* | \ + /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \ + ?:\\/os2\\/install\\/* | ?:\\/OS2\\/INSTALL\\/* | \ + /usr/ucb/* ) ;; + *) + # OSF1 and SCO ODT 3.0 have their own names for install. + # Don't use installbsd from OSF since it installs stuff as root + # by default. + for ac_prog in ginstall scoinst install; do + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then + if test $ac_prog = install && + grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # AIX install. It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +# Extract the first word of "find", so it can be a program name with args. +set dummy find; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_FIND+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$FIND"; then + ac_cv_prog_FIND="$FIND" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_FIND="find" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_FIND" && ac_cv_prog_FIND=":" +fi +fi +FIND=$ac_cv_prog_FIND +if test -n "$FIND"; then + echo "$as_me:$LINENO: result: $FIND" >&5 +echo "${ECHO_T}$FIND" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +# Extract the first word of "makedepend", so it can be a program name with args. +set dummy makedepend; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_MAKEDEPEND+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$MAKEDEPEND"; then + ac_cv_prog_MAKEDEPEND="$MAKEDEPEND" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_MAKEDEPEND="makedepend" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_MAKEDEPEND" && ac_cv_prog_MAKEDEPEND=":" +fi +fi +MAKEDEPEND=$ac_cv_prog_MAKEDEPEND +if test -n "$MAKEDEPEND"; then + echo "$as_me:$LINENO: result: $MAKEDEPEND" >&5 +echo "${ECHO_T}$MAKEDEPEND" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + +echo "$as_me:$LINENO: checking for dlopen in -ldl" >&5 +echo $ECHO_N "checking for dlopen in -ldl... $ECHO_C" >&6 +if test "${ac_cv_lib_dl_dlopen+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldl $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dlopen (); +int +main () +{ +dlopen (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dl_dlopen=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dl_dlopen=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dl_dlopen" >&5 +echo "${ECHO_T}$ac_cv_lib_dl_dlopen" >&6 +if test $ac_cv_lib_dl_dlopen = yes; then + have_dl=yes +else + have_dl=no +fi + + + +# +# Try to locate the X Window System include files and libraries +# and add /usr/local to include and lib path and add -lm (for testing) +# + +echo "$as_me:$LINENO: checking for X" >&5 +echo $ECHO_N "checking for X... $ECHO_C" >&6 + + +# Check whether --with-x or --without-x was given. +if test "${with_x+set}" = set; then + withval="$with_x" + +fi; +# $have_x is `yes', `no', `disabled', or empty when we do not yet know. +if test "x$with_x" = xno; then + # The user explicitly disabled X. + have_x=disabled +else + if test "x$x_includes" != xNONE && test "x$x_libraries" != xNONE; then + # Both variables are already set. + have_x=yes + else + if test "${ac_cv_have_x+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # One or both of the vars are not set, and there is no cached value. +ac_x_includes=no ac_x_libraries=no +rm -fr conftest.dir +if mkdir conftest.dir; then + cd conftest.dir + # Make sure to not put "make" in the Imakefile rules, since we grep it out. + cat >Imakefile <<'_ACEOF' +acfindx: + @echo 'ac_im_incroot="${INCROOT}"; ac_im_usrlibdir="${USRLIBDIR}"; ac_im_libdir="${LIBDIR}"' +_ACEOF + if (xmkmf) >/dev/null 2>/dev/null && test -f Makefile; then + # GNU make sometimes prints "make[1]: Entering...", which would confuse us. + eval `${MAKE-make} acfindx 2>/dev/null | grep -v make` + # Open Windows xmkmf reportedly sets LIBDIR instead of USRLIBDIR. + for ac_extension in a so sl; do + if test ! -f $ac_im_usrlibdir/libX11.$ac_extension && + test -f $ac_im_libdir/libX11.$ac_extension; then + ac_im_usrlibdir=$ac_im_libdir; break + fi + done + # Screen out bogus values from the imake configuration. They are + # bogus both because they are the default anyway, and because + # using them would break gcc on systems where it needs fixed includes. + case $ac_im_incroot in + /usr/include) ;; + *) test -f "$ac_im_incroot/X11/Xos.h" && ac_x_includes=$ac_im_incroot;; + esac + case $ac_im_usrlibdir in + /usr/lib | /lib) ;; + *) test -d "$ac_im_usrlibdir" && ac_x_libraries=$ac_im_usrlibdir ;; + esac + fi + cd .. + rm -fr conftest.dir +fi + +# Standard set of common directories for X headers. +# Check X11 before X11Rn because it is often a symlink to the current release. +ac_x_header_dirs=' +/usr/X11/include +/usr/X11R6/include +/usr/X11R5/include +/usr/X11R4/include + +/usr/include/X11 +/usr/include/X11R6 +/usr/include/X11R5 +/usr/include/X11R4 + +/usr/local/X11/include +/usr/local/X11R6/include +/usr/local/X11R5/include +/usr/local/X11R4/include + +/usr/local/include/X11 +/usr/local/include/X11R6 +/usr/local/include/X11R5 +/usr/local/include/X11R4 + +/usr/X386/include +/usr/x386/include +/usr/XFree86/include/X11 + +/usr/include +/usr/local/include +/usr/unsupported/include +/usr/athena/include +/usr/local/x11r5/include +/usr/lpp/Xamples/include + +/usr/openwin/include +/usr/openwin/share/include' + +if test "$ac_x_includes" = no; then + # Guess where to find include files, by looking for Intrinsic.h. + # First, try using that file with no special directory specified. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # We can compile using X headers with no special include directory. +ac_x_includes= +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + for ac_dir in $ac_x_header_dirs; do + if test -r "$ac_dir/X11/Intrinsic.h"; then + ac_x_includes=$ac_dir + break + fi +done +fi +rm -f conftest.err conftest.$ac_ext +fi # $ac_x_includes = no + +if test "$ac_x_libraries" = no; then + # Check for the libraries. + # See if we find them without any special options. + # Don't add to $LIBS permanently. + ac_save_LIBS=$LIBS + LIBS="-lXt $LIBS" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +int +main () +{ +XtMalloc (0) + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + LIBS=$ac_save_LIBS +# We can link X programs with no special library path. +ac_x_libraries= +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +LIBS=$ac_save_LIBS +for ac_dir in `echo "$ac_x_includes $ac_x_header_dirs" | sed s/include/lib/g` +do + # Don't even attempt the hair of trying to link an X program! + for ac_extension in a so sl; do + if test -r $ac_dir/libXt.$ac_extension; then + ac_x_libraries=$ac_dir + break 2 + fi + done +done +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi # $ac_x_libraries = no + +if test "$ac_x_includes" = no || test "$ac_x_libraries" = no; then + # Didn't find X anywhere. Cache the known absence of X. + ac_cv_have_x="have_x=no" +else + # Record where we found X for the cache. + ac_cv_have_x="have_x=yes \ + ac_x_includes=$ac_x_includes ac_x_libraries=$ac_x_libraries" +fi +fi + + fi + eval "$ac_cv_have_x" +fi # $with_x != no + +if test "$have_x" != yes; then + echo "$as_me:$LINENO: result: $have_x" >&5 +echo "${ECHO_T}$have_x" >&6 + no_x=yes +else + # If each of the values was on the command line, it overrides each guess. + test "x$x_includes" = xNONE && x_includes=$ac_x_includes + test "x$x_libraries" = xNONE && x_libraries=$ac_x_libraries + # Update the cache value to reflect the command line values. + ac_cv_have_x="have_x=yes \ + ac_x_includes=$x_includes ac_x_libraries=$x_libraries" + echo "$as_me:$LINENO: result: libraries $x_libraries, headers $x_includes" >&5 +echo "${ECHO_T}libraries $x_libraries, headers $x_includes" >&6 +fi + +if test "$no_x" = yes; then + # Not all programs may use this symbol, but it does not hurt to define it. + +cat >>confdefs.h <<\_ACEOF +#define X_DISPLAY_MISSING 1 +_ACEOF + + X_CFLAGS= X_PRE_LIBS= X_LIBS= X_EXTRA_LIBS= +else + if test -n "$x_includes"; then + X_CFLAGS="$X_CFLAGS -I$x_includes" + fi + + # It would also be nice to do this for all -L options, not just this one. + if test -n "$x_libraries"; then + X_LIBS="$X_LIBS -L$x_libraries" + # For Solaris; some versions of Sun CC require a space after -R and + # others require no space. Words are not sufficient . . . . + case `(uname -sr) 2>/dev/null` in + "SunOS 5"*) + echo "$as_me:$LINENO: checking whether -R must be followed by a space" >&5 +echo $ECHO_N "checking whether -R must be followed by a space... $ECHO_C" >&6 + ac_xsave_LIBS=$LIBS; LIBS="$LIBS -R$x_libraries" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_R_nospace=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_R_nospace=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + if test $ac_R_nospace = yes; then + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + X_LIBS="$X_LIBS -R$x_libraries" + else + LIBS="$ac_xsave_LIBS -R $x_libraries" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_R_space=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_R_space=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + if test $ac_R_space = yes; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + X_LIBS="$X_LIBS -R $x_libraries" + else + echo "$as_me:$LINENO: result: neither works" >&5 +echo "${ECHO_T}neither works" >&6 + fi + fi + LIBS=$ac_xsave_LIBS + esac + fi + + # Check for system-dependent libraries X programs must link with. + # Do this before checking for the system-independent R6 libraries + # (-lICE), since we may need -lsocket or whatever for X linking. + + if test "$ISC" = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lnsl_s -linet" + else + # Martyn Johnson says this is needed for Ultrix, if the X + # libraries were built with DECnet support. And Karl Berry says + # the Alpha needs dnet_stub (dnet does not exist). + ac_xsave_LIBS="$LIBS"; LIBS="$LIBS $X_LIBS -lX11" + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char XOpenDisplay (); +int +main () +{ +XOpenDisplay (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +echo "$as_me:$LINENO: checking for dnet_ntoa in -ldnet" >&5 +echo $ECHO_N "checking for dnet_ntoa in -ldnet... $ECHO_C" >&6 +if test "${ac_cv_lib_dnet_dnet_ntoa+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldnet $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dnet_ntoa (); +int +main () +{ +dnet_ntoa (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dnet_dnet_ntoa=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dnet_dnet_ntoa=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dnet_dnet_ntoa" >&5 +echo "${ECHO_T}$ac_cv_lib_dnet_dnet_ntoa" >&6 +if test $ac_cv_lib_dnet_dnet_ntoa = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -ldnet" +fi + + if test $ac_cv_lib_dnet_dnet_ntoa = no; then + echo "$as_me:$LINENO: checking for dnet_ntoa in -ldnet_stub" >&5 +echo $ECHO_N "checking for dnet_ntoa in -ldnet_stub... $ECHO_C" >&6 +if test "${ac_cv_lib_dnet_stub_dnet_ntoa+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-ldnet_stub $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char dnet_ntoa (); +int +main () +{ +dnet_ntoa (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_dnet_stub_dnet_ntoa=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_dnet_stub_dnet_ntoa=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_dnet_stub_dnet_ntoa" >&5 +echo "${ECHO_T}$ac_cv_lib_dnet_stub_dnet_ntoa" >&6 +if test $ac_cv_lib_dnet_stub_dnet_ntoa = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -ldnet_stub" +fi + + fi +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext + LIBS="$ac_xsave_LIBS" + + # msh@cis.ufl.edu says -lnsl (and -lsocket) are needed for his 386/AT, + # to get the SysV transport functions. + # Chad R. Larson says the Pyramis MIS-ES running DC/OSx (SVR4) + # needs -lnsl. + # The nsl library prevents programs from opening the X display + # on Irix 5.2, according to T.E. Dickey. + # The functions gethostbyname, getservbyname, and inet_addr are + # in -lbsd on LynxOS 3.0.1/i386, according to Lars Hecking. + echo "$as_me:$LINENO: checking for gethostbyname" >&5 +echo $ECHO_N "checking for gethostbyname... $ECHO_C" >&6 +if test "${ac_cv_func_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gethostbyname to an innocuous variant, in case declares gethostbyname. + For example, HP-UX 11i declares gettimeofday. */ +#define gethostbyname innocuous_gethostbyname + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gethostbyname (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gethostbyname + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gethostbyname) || defined (__stub___gethostbyname) +choke me +#else +char (*f) () = gethostbyname; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gethostbyname; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_func_gethostbyname" >&6 + + if test $ac_cv_func_gethostbyname = no; then + echo "$as_me:$LINENO: checking for gethostbyname in -lnsl" >&5 +echo $ECHO_N "checking for gethostbyname in -lnsl... $ECHO_C" >&6 +if test "${ac_cv_lib_nsl_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lnsl $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +int +main () +{ +gethostbyname (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_nsl_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_nsl_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_nsl_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_lib_nsl_gethostbyname" >&6 +if test $ac_cv_lib_nsl_gethostbyname = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lnsl" +fi + + if test $ac_cv_lib_nsl_gethostbyname = no; then + echo "$as_me:$LINENO: checking for gethostbyname in -lbsd" >&5 +echo $ECHO_N "checking for gethostbyname in -lbsd... $ECHO_C" >&6 +if test "${ac_cv_lib_bsd_gethostbyname+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lbsd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gethostbyname (); +int +main () +{ +gethostbyname (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_bsd_gethostbyname=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_bsd_gethostbyname=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_bsd_gethostbyname" >&5 +echo "${ECHO_T}$ac_cv_lib_bsd_gethostbyname" >&6 +if test $ac_cv_lib_bsd_gethostbyname = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lbsd" +fi + + fi + fi + + # lieder@skyler.mavd.honeywell.com says without -lsocket, + # socket/setsockopt and other routines are undefined under SCO ODT + # 2.0. But -lsocket is broken on IRIX 5.2 (and is not necessary + # on later versions), says Simon Leinen: it contains gethostby* + # variants that don't use the name server (or something). -lsocket + # must be given before -lnsl if both are needed. We assume that + # if connect needs -lnsl, so does gethostbyname. + echo "$as_me:$LINENO: checking for connect" >&5 +echo $ECHO_N "checking for connect... $ECHO_C" >&6 +if test "${ac_cv_func_connect+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define connect to an innocuous variant, in case declares connect. + For example, HP-UX 11i declares gettimeofday. */ +#define connect innocuous_connect + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char connect (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef connect + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char connect (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_connect) || defined (__stub___connect) +choke me +#else +char (*f) () = connect; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != connect; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_connect=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_connect=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_connect" >&5 +echo "${ECHO_T}$ac_cv_func_connect" >&6 + + if test $ac_cv_func_connect = no; then + echo "$as_me:$LINENO: checking for connect in -lsocket" >&5 +echo $ECHO_N "checking for connect in -lsocket... $ECHO_C" >&6 +if test "${ac_cv_lib_socket_connect+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lsocket $X_EXTRA_LIBS $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char connect (); +int +main () +{ +connect (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_socket_connect=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_socket_connect=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_socket_connect" >&5 +echo "${ECHO_T}$ac_cv_lib_socket_connect" >&6 +if test $ac_cv_lib_socket_connect = yes; then + X_EXTRA_LIBS="-lsocket $X_EXTRA_LIBS" +fi + + fi + + # Guillermo Gomez says -lposix is necessary on A/UX. + echo "$as_me:$LINENO: checking for remove" >&5 +echo $ECHO_N "checking for remove... $ECHO_C" >&6 +if test "${ac_cv_func_remove+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define remove to an innocuous variant, in case declares remove. + For example, HP-UX 11i declares gettimeofday. */ +#define remove innocuous_remove + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char remove (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef remove + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char remove (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_remove) || defined (__stub___remove) +choke me +#else +char (*f) () = remove; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != remove; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_remove=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_remove=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_remove" >&5 +echo "${ECHO_T}$ac_cv_func_remove" >&6 + + if test $ac_cv_func_remove = no; then + echo "$as_me:$LINENO: checking for remove in -lposix" >&5 +echo $ECHO_N "checking for remove in -lposix... $ECHO_C" >&6 +if test "${ac_cv_lib_posix_remove+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lposix $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char remove (); +int +main () +{ +remove (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_posix_remove=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_posix_remove=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_posix_remove" >&5 +echo "${ECHO_T}$ac_cv_lib_posix_remove" >&6 +if test $ac_cv_lib_posix_remove = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lposix" +fi + + fi + + # BSDI BSD/OS 2.1 needs -lipc for XOpenDisplay. + echo "$as_me:$LINENO: checking for shmat" >&5 +echo $ECHO_N "checking for shmat... $ECHO_C" >&6 +if test "${ac_cv_func_shmat+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define shmat to an innocuous variant, in case declares shmat. + For example, HP-UX 11i declares gettimeofday. */ +#define shmat innocuous_shmat + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char shmat (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef shmat + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char shmat (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_shmat) || defined (__stub___shmat) +choke me +#else +char (*f) () = shmat; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != shmat; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_shmat=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_shmat=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_shmat" >&5 +echo "${ECHO_T}$ac_cv_func_shmat" >&6 + + if test $ac_cv_func_shmat = no; then + echo "$as_me:$LINENO: checking for shmat in -lipc" >&5 +echo $ECHO_N "checking for shmat in -lipc... $ECHO_C" >&6 +if test "${ac_cv_lib_ipc_shmat+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lipc $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char shmat (); +int +main () +{ +shmat (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_ipc_shmat=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_ipc_shmat=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_ipc_shmat" >&5 +echo "${ECHO_T}$ac_cv_lib_ipc_shmat" >&6 +if test $ac_cv_lib_ipc_shmat = yes; then + X_EXTRA_LIBS="$X_EXTRA_LIBS -lipc" +fi + + fi + fi + + # Check for libraries that X11R6 Xt/Xaw programs need. + ac_save_LDFLAGS=$LDFLAGS + test -n "$x_libraries" && LDFLAGS="$LDFLAGS -L$x_libraries" + # SM needs ICE to (dynamically) link under SunOS 4.x (so we have to + # check for ICE first), but we must link in the order -lSM -lICE or + # we get undefined symbols. So assume we have SM if we have ICE. + # These have to be linked with before -lX11, unlike the other + # libraries we check for below, so use a different variable. + # John Interrante, Karl Berry + echo "$as_me:$LINENO: checking for IceConnectionNumber in -lICE" >&5 +echo $ECHO_N "checking for IceConnectionNumber in -lICE... $ECHO_C" >&6 +if test "${ac_cv_lib_ICE_IceConnectionNumber+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lICE $X_EXTRA_LIBS $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char IceConnectionNumber (); +int +main () +{ +IceConnectionNumber (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_ICE_IceConnectionNumber=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_ICE_IceConnectionNumber=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_ICE_IceConnectionNumber" >&5 +echo "${ECHO_T}$ac_cv_lib_ICE_IceConnectionNumber" >&6 +if test $ac_cv_lib_ICE_IceConnectionNumber = yes; then + X_PRE_LIBS="$X_PRE_LIBS -lSM -lICE" +fi + + LDFLAGS=$ac_save_LDFLAGS + +fi + +CFLAGS="$CFLAGS $X_CFLAGS -I/usr/local/include" +LDFLAGS="$LDFLAGS $X_LIBS -L/usr/local/lib" + + +DO_PS='#' +DO_FIG='#' +DO_X11='#' +DO_GD='#' +DO_WIN32='#' + + +# +# check supported devices +# +echo "$as_me:$LINENO: checking for main in -lm" >&5 +echo $ECHO_N "checking for main in -lm... $ECHO_C" >&6 +if test "${ac_cv_lib_m_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lm $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_m_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_m_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_m_main" >&5 +echo "${ECHO_T}$ac_cv_lib_m_main" >&6 +if test $ac_cv_lib_m_main = yes; then + DO_PS='';DO_FIG='';LDFLAGS="$LDFLAGS -lm";cat >>confdefs.h <<\_ACEOF +#define DO_PS 1 +_ACEOF + cat >>confdefs.h <<\_ACEOF +#define DO_FIG 1 +_ACEOF + +else + break +fi + +echo "$as_me:$LINENO: checking for main in -lX11" >&5 +echo $ECHO_N "checking for main in -lX11... $ECHO_C" >&6 +if test "${ac_cv_lib_X11_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lX11 $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_X11_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_X11_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_X11_main" >&5 +echo "${ECHO_T}$ac_cv_lib_X11_main" >&6 +if test $ac_cv_lib_X11_main = yes; then + DO_X11='';LDFLAGS="$LDFLAGS -lX11";cat >>confdefs.h <<\_ACEOF +#define DO_X11 1 +_ACEOF + +fi + +echo "$as_me:$LINENO: checking for main in -lgd" >&5 +echo $ECHO_N "checking for main in -lgd... $ECHO_C" >&6 +if test "${ac_cv_lib_gd_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lgd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_gd_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_gd_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_gd_main" >&5 +echo "${ECHO_T}$ac_cv_lib_gd_main" >&6 +if test $ac_cv_lib_gd_main = yes; then + have_gd=yes +else + have_gd=no +fi + +if test "$have_gd" = yes +then + LDFLAGS="$LDFLAGS -lgd" + echo "$as_me:$LINENO: checking for gdImagePng" >&5 +echo $ECHO_N "checking for gdImagePng... $ECHO_C" >&6 +if test "${ac_cv_func_gdImagePng+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gdImagePng to an innocuous variant, in case declares gdImagePng. + For example, HP-UX 11i declares gettimeofday. */ +#define gdImagePng innocuous_gdImagePng + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gdImagePng (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gdImagePng + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gdImagePng (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gdImagePng) || defined (__stub___gdImagePng) +choke me +#else +char (*f) () = gdImagePng; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gdImagePng; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gdImagePng=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gdImagePng=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gdImagePng" >&5 +echo "${ECHO_T}$ac_cv_func_gdImagePng" >&6 +if test $ac_cv_func_gdImagePng = yes; then + DO_GD='';cat >>confdefs.h <<\_ACEOF +#define DO_GD 1 +_ACEOF + +fi + +fi + +# +# handling cygwin environment (and gd for cygwin == bgd) +# + +case $host_os in + *cygwin* ) CYGWIN=yes;; + * ) CYGWIN=no;; +esac + +if test "$CYGWIN" = yes +then + LDFLAGS="$LDFLAGS -L/lib/w32api" + echo "$as_me:$LINENO: checking for main in -lgdi32" >&5 +echo $ECHO_N "checking for main in -lgdi32... $ECHO_C" >&6 +if test "${ac_cv_lib_gdi32_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lgdi32 $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_gdi32_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_gdi32_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_gdi32_main" >&5 +echo "${ECHO_T}$ac_cv_lib_gdi32_main" >&6 +if test $ac_cv_lib_gdi32_main = yes; then + DO_WIN32='';LDFLAGS="$LDFLAGS -lgdi32";cat >>confdefs.h <<\_ACEOF +#define DO_WIN32 1 +_ACEOF + +fi + + echo "$as_me:$LINENO: checking for main in -lbgd" >&5 +echo $ECHO_N "checking for main in -lbgd... $ECHO_C" >&6 +if test "${ac_cv_lib_bgd_main+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_check_lib_save_LIBS=$LIBS +LIBS="-lbgd $LIBS" +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + + +int +main () +{ +main (); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_lib_bgd_main=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_lib_bgd_main=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +LIBS=$ac_check_lib_save_LIBS +fi +echo "$as_me:$LINENO: result: $ac_cv_lib_bgd_main" >&5 +echo "${ECHO_T}$ac_cv_lib_bgd_main" >&6 +if test $ac_cv_lib_bgd_main = yes; then + have_bgd=yes +else + have_bgd=no +fi + + if test "$have_bgd" = yes + then + LDFLAGS="$LDFLAGS -lbgd" + echo "$as_me:$LINENO: checking for gdImagePng" >&5 +echo $ECHO_N "checking for gdImagePng... $ECHO_C" >&6 +if test "${ac_cv_func_gdImagePng+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define gdImagePng to an innocuous variant, in case declares gdImagePng. + For example, HP-UX 11i declares gettimeofday. */ +#define gdImagePng innocuous_gdImagePng + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char gdImagePng (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef gdImagePng + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char gdImagePng (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_gdImagePng) || defined (__stub___gdImagePng) +choke me +#else +char (*f) () = gdImagePng; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != gdImagePng; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_func_gdImagePng=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_func_gdImagePng=no +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_func_gdImagePng" >&5 +echo "${ECHO_T}$ac_cv_func_gdImagePng" >&6 +if test $ac_cv_func_gdImagePng = yes; then + DO_GD='';cat >>confdefs.h <<\_ACEOF +#define DO_GD 1 +_ACEOF + +fi + + fi +fi + +# +# Declare variables which we want substituted in the Makefile.in's +# + + + + + + +echo "$as_me:$LINENO: checking for egrep" >&5 +echo $ECHO_N "checking for egrep... $ECHO_C" >&6 +if test "${ac_cv_prog_egrep+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if echo a | (grep -E '(a|b)') >/dev/null 2>&1 + then ac_cv_prog_egrep='grep -E' + else ac_cv_prog_egrep='egrep' + fi +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5 +echo "${ECHO_T}$ac_cv_prog_egrep" >&6 + EGREP=$ac_cv_prog_egrep + + +echo "$as_me:$LINENO: checking for ANSI C header files" >&5 +echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6 +if test "${ac_cv_header_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_header_stdc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_header_stdc=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + +if test $ac_cv_header_stdc = yes; then + # SunOS 4.x string.h does not declare mem*, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "memchr" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "free" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi. + if test "$cross_compiling" = yes; then + : +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#if ((' ' & 0x0FF) == 0x020) +# define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +#else +# define ISLOWER(c) \ + (('a' <= (c) && (c) <= 'i') \ + || ('j' <= (c) && (c) <= 'r') \ + || ('s' <= (c) && (c) <= 'z')) +# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +#endif + +#define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +int +main () +{ + int i; + for (i = 0; i < 256; i++) + if (XOR (islower (i), ISLOWER (i)) + || toupper (i) != TOUPPER (i)) + exit(2); + exit (0); +} +_ACEOF +rm -f conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && { ac_try='./conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: program exited with status $ac_status" >&5 +echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +( exit $ac_status ) +ac_cv_header_stdc=no +fi +rm -f core *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext +fi +fi +fi +echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5 +echo "${ECHO_T}$ac_cv_header_stdc" >&6 +if test $ac_cv_header_stdc = yes; then + +cat >>confdefs.h <<\_ACEOF +#define STDC_HEADERS 1 +_ACEOF + +fi + +# On IRIX 5.3, sys/types and inttypes.h are conflicting. + + + + + + + + + +for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default + +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_Header=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_Header=no" +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + +for ac_header in limits.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +else + # Is the header compilable? +echo "$as_me:$LINENO: checking $ac_header usability" >&5 +echo $ECHO_N "checking $ac_header usability... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_header_compiler=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_header_compiler=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_compiler" >&5 +echo "${ECHO_T}$ac_header_compiler" >&6 + +# Is the header present? +echo "$as_me:$LINENO: checking $ac_header presence" >&5 +echo $ECHO_N "checking $ac_header presence... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include <$ac_header> +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + ac_header_preproc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + ac_header_preproc=no +fi +rm -f conftest.err conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_preproc" >&5 +echo "${ECHO_T}$ac_header_preproc" >&6 + +# So? What about this header? +case $ac_header_compiler:$ac_header_preproc:$ac_c_preproc_warn_flag in + yes:no: ) + { echo "$as_me:$LINENO: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&5 +echo "$as_me: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the compiler's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the compiler's result" >&2;} + ac_header_preproc=yes + ;; + no:yes:* ) + { echo "$as_me:$LINENO: WARNING: $ac_header: present but cannot be compiled" >&5 +echo "$as_me: WARNING: $ac_header: present but cannot be compiled" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: check for missing prerequisite headers?" >&5 +echo "$as_me: WARNING: $ac_header: check for missing prerequisite headers?" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: see the Autoconf documentation" >&5 +echo "$as_me: WARNING: $ac_header: see the Autoconf documentation" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&5 +echo "$as_me: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the preprocessor's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the preprocessor's result" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: in the future, the compiler will take precedence" >&5 +echo "$as_me: WARNING: $ac_header: in the future, the compiler will take precedence" >&2;} + ( + cat <<\_ASBOX +## ------------------------------------------ ## +## Report this to the AC_PACKAGE_NAME lists. ## +## ------------------------------------------ ## +_ASBOX + ) | + sed "s/^/$as_me: WARNING: /" >&2 + ;; +esac +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + eval "$as_ac_Header=\$ac_header_preproc" +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 + +fi +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + + +# +# finally create makefiles using Makefile.in +# +echo + ac_config_files="$ac_config_files Makefile demo/Makefile g2_perl/Makefile.PL" +cat >confcache <<\_ACEOF +# This file is a shell script that caches the results of configure +# tests run on this system so they can be shared between configure +# scripts and configure runs, see configure's option --config-cache. +# It is not useful on other systems. If it contains results you don't +# want to keep, you may remove or edit it. +# +# config.status only pays attention to the cache file if you give it +# the --recheck option to rerun configure. +# +# `ac_cv_env_foo' variables (set or unset) will be overridden when +# loading this file, other *unset* `ac_cv_foo' will be assigned the +# following values. + +_ACEOF + +# The following way of writing the cache mishandles newlines in values, +# but we know of no workaround that is simple, portable, and efficient. +# So, don't put newlines in cache variables' values. +# Ultrix sh set writes to stderr and can't be redirected directly, +# and sets the high bit in the cache file unless we assign to the vars. +{ + (set) 2>&1 | + case `(ac_space=' '; set | grep ac_space) 2>&1` in + *ac_space=\ *) + # `set' does not quote correctly, so add quotes (double-quote + # substitution turns \\\\ into \\, and sed turns \\ into \). + sed -n \ + "s/'/'\\\\''/g; + s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='\\2'/p" + ;; + *) + # `set' quotes correctly as required by POSIX, so do not add quotes. + sed -n \ + "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p" + ;; + esac; +} | + sed ' + t clear + : clear + s/^\([^=]*\)=\(.*[{}].*\)$/test "${\1+set}" = set || &/ + t end + /^ac_cv_env/!s/^\([^=]*\)=\(.*\)$/\1=${\1=\2}/ + : end' >>confcache +if diff $cache_file confcache >/dev/null 2>&1; then :; else + if test -w $cache_file; then + test "x$cache_file" != "x/dev/null" && echo "updating cache $cache_file" + cat confcache >$cache_file + else + echo "not updating unwritable cache $cache_file" + fi +fi +rm -f confcache + +test "x$prefix" = xNONE && prefix=$ac_default_prefix +# Let make expand exec_prefix. +test "x$exec_prefix" = xNONE && exec_prefix='${prefix}' + +# VPATH may cause trouble with some makes, so we remove $(srcdir), +# ${srcdir} and @srcdir@ from VPATH if srcdir is ".", strip leading and +# trailing colons and then remove the whole line if VPATH becomes empty +# (actually we leave an empty line to preserve line numbers). +if test "x$srcdir" = x.; then + ac_vpsub='/^[ ]*VPATH[ ]*=/{ +s/:*\$(srcdir):*/:/; +s/:*\${srcdir}:*/:/; +s/:*@srcdir@:*/:/; +s/^\([^=]*=[ ]*\):*/\1/; +s/:*$//; +s/^[^=]*=[ ]*$//; +}' +fi + +# Transform confdefs.h into DEFS. +# Protect against shell expansion while executing Makefile rules. +# Protect against Makefile macro expansion. +# +# If the first sed substitution is executed (which looks for macros that +# take arguments), then we branch to the quote section. Otherwise, +# look for a macro that doesn't take arguments. +cat >confdef2opt.sed <<\_ACEOF +t clear +: clear +s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*([^)]*)\)[ ]*\(.*\),-D\1=\2,g +t quote +s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\),-D\1=\2,g +t quote +d +: quote +s,[ `~#$^&*(){}\\|;'"<>?],\\&,g +s,\[,\\&,g +s,\],\\&,g +s,\$,$$,g +p +_ACEOF +# We use echo to avoid assuming a particular line-breaking character. +# The extra dot is to prevent the shell from consuming trailing +# line-breaks from the sub-command output. A line-break within +# single-quotes doesn't work because, if this script is created in a +# platform that uses two characters for line-breaks (e.g., DOS), tr +# would break. +ac_LF_and_DOT=`echo; echo .` +DEFS=`sed -n -f confdef2opt.sed confdefs.h | tr "$ac_LF_and_DOT" ' .'` +rm -f confdef2opt.sed + + +ac_libobjs= +ac_ltlibobjs= +for ac_i in : $LIBOBJS; do test "x$ac_i" = x: && continue + # 1. Remove the extension, and $U if already installed. + ac_i=`echo "$ac_i" | + sed 's/\$U\././;s/\.o$//;s/\.obj$//'` + # 2. Add them. + ac_libobjs="$ac_libobjs $ac_i\$U.$ac_objext" + ac_ltlibobjs="$ac_ltlibobjs $ac_i"'$U.lo' +done +LIBOBJS=$ac_libobjs + +LTLIBOBJS=$ac_ltlibobjs + + + +: ${CONFIG_STATUS=./config.status} +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files $CONFIG_STATUS" +{ echo "$as_me:$LINENO: creating $CONFIG_STATUS" >&5 +echo "$as_me: creating $CONFIG_STATUS" >&6;} +cat >$CONFIG_STATUS <<_ACEOF +#! $SHELL +# Generated by $as_me. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=\${CONFIG_SHELL-$SHELL} +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. 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Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. 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Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +_ACEOF + +# Files that config.status was made for. +if test -n "$ac_config_files"; then + echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_headers"; then + echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_links"; then + echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_commands"; then + echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS +fi + +cat >>$CONFIG_STATUS <<\_ACEOF + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + +Configuration files: +$config_files + +Report bugs to ." +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF +ac_cs_version="\\ +config.status +configured by $0, generated by GNU Autoconf 2.59, + with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=$srcdir +INSTALL="$INSTALL" +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +# If no file are specified by the user, then we need to provide default +# value. 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Make it in the build tree +# simply because there is no reason to put it here, and in addition, +# creating and moving files from /tmp can sometimes cause problems. +# Create a temporary directory, and hook for its removal unless debugging. +$debug || +{ + trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0 + trap '{ (exit 1); exit 1; }' 1 2 13 15 +} + +# Create a (secure) tmp directory for tmp files. + +{ + tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` && + test -n "$tmp" && test -d "$tmp" +} || +{ + tmp=./confstat$$-$RANDOM + (umask 077 && mkdir $tmp) +} || +{ + echo "$me: cannot create a temporary directory in ." >&2 + { (exit 1); exit 1; } +} + +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF + +# +# CONFIG_FILES section. +# + +# No need to generate the scripts if there are no CONFIG_FILES. +# This happens for instance when ./config.status config.h +if test -n "\$CONFIG_FILES"; then + # Protect against being on the right side of a sed subst in config.status. + sed 's/,@/@@/; s/@,/@@/; s/,;t t\$/@;t t/; /@;t t\$/s/[\\\\&,]/\\\\&/g; + s/@@/,@/; s/@@/@,/; s/@;t t\$/,;t t/' >\$tmp/subs.sed <<\\CEOF +s,@SHELL@,$SHELL,;t t +s,@PATH_SEPARATOR@,$PATH_SEPARATOR,;t t +s,@PACKAGE_NAME@,$PACKAGE_NAME,;t t +s,@PACKAGE_TARNAME@,$PACKAGE_TARNAME,;t t +s,@PACKAGE_VERSION@,$PACKAGE_VERSION,;t t +s,@PACKAGE_STRING@,$PACKAGE_STRING,;t t +s,@PACKAGE_BUGREPORT@,$PACKAGE_BUGREPORT,;t t +s,@exec_prefix@,$exec_prefix,;t t +s,@prefix@,$prefix,;t t +s,@program_transform_name@,$program_transform_name,;t t +s,@bindir@,$bindir,;t t +s,@sbindir@,$sbindir,;t t +s,@libexecdir@,$libexecdir,;t t +s,@datadir@,$datadir,;t t +s,@sysconfdir@,$sysconfdir,;t t +s,@sharedstatedir@,$sharedstatedir,;t t +s,@localstatedir@,$localstatedir,;t t +s,@libdir@,$libdir,;t t +s,@includedir@,$includedir,;t t +s,@oldincludedir@,$oldincludedir,;t t +s,@infodir@,$infodir,;t t +s,@mandir@,$mandir,;t t +s,@build_alias@,$build_alias,;t t +s,@host_alias@,$host_alias,;t t +s,@target_alias@,$target_alias,;t t +s,@DEFS@,$DEFS,;t t +s,@ECHO_C@,$ECHO_C,;t t +s,@ECHO_N@,$ECHO_N,;t t +s,@ECHO_T@,$ECHO_T,;t t +s,@LIBS@,$LIBS,;t t +s,@build@,$build,;t t +s,@build_cpu@,$build_cpu,;t t +s,@build_vendor@,$build_vendor,;t t +s,@build_os@,$build_os,;t t +s,@host@,$host,;t t +s,@host_cpu@,$host_cpu,;t t +s,@host_vendor@,$host_vendor,;t t +s,@host_os@,$host_os,;t t +s,@LD_SHARED@,$LD_SHARED,;t t +s,@LD_SHARED_FLAGS@,$LD_SHARED_FLAGS,;t t +s,@LD_SHARED_OPT@,$LD_SHARED_OPT,;t t +s,@LD_SHARED_EXT@,$LD_SHARED_EXT,;t t +s,@CC@,$CC,;t t +s,@CFLAGS@,$CFLAGS,;t t +s,@LDFLAGS@,$LDFLAGS,;t t +s,@CPPFLAGS@,$CPPFLAGS,;t t +s,@ac_ct_CC@,$ac_ct_CC,;t t +s,@EXEEXT@,$EXEEXT,;t t +s,@OBJEXT@,$OBJEXT,;t t +s,@CPP@,$CPP,;t t +s,@CXX@,$CXX,;t t +s,@CXXFLAGS@,$CXXFLAGS,;t t +s,@ac_ct_CXX@,$ac_ct_CXX,;t t +s,@RANLIB@,$RANLIB,;t t +s,@ac_ct_RANLIB@,$ac_ct_RANLIB,;t t +s,@INSTALL_PROGRAM@,$INSTALL_PROGRAM,;t t +s,@INSTALL_SCRIPT@,$INSTALL_SCRIPT,;t t +s,@INSTALL_DATA@,$INSTALL_DATA,;t t +s,@FIND@,$FIND,;t t +s,@MAKEDEPEND@,$MAKEDEPEND,;t t +s,@X_CFLAGS@,$X_CFLAGS,;t t +s,@X_PRE_LIBS@,$X_PRE_LIBS,;t t +s,@X_LIBS@,$X_LIBS,;t t +s,@X_EXTRA_LIBS@,$X_EXTRA_LIBS,;t t +s,@DO_PS@,$DO_PS,;t t +s,@DO_FIG@,$DO_FIG,;t t +s,@DO_X11@,$DO_X11,;t t +s,@DO_WIN32@,$DO_WIN32,;t t +s,@DO_GD@,$DO_GD,;t t +s,@EGREP@,$EGREP,;t t +s,@LIBOBJS@,$LIBOBJS,;t t +s,@LTLIBOBJS@,$LTLIBOBJS,;t t +CEOF + +_ACEOF + + cat >>$CONFIG_STATUS <<\_ACEOF + # Split the substitutions into bite-sized pieces for seds with + # small command number limits, like on Digital OSF/1 and HP-UX. + ac_max_sed_lines=48 + ac_sed_frag=1 # Number of current file. + ac_beg=1 # First line for current file. + ac_end=$ac_max_sed_lines # Line after last line for current file. + ac_more_lines=: + ac_sed_cmds= + while $ac_more_lines; do + if test $ac_beg -gt 1; then + sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + else + sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + fi + if test ! -s $tmp/subs.frag; then + ac_more_lines=false + else + # The purpose of the label and of the branching condition is to + # speed up the sed processing (if there are no `@' at all, there + # is no need to browse any of the substitutions). + # These are the two extra sed commands mentioned above. + (echo ':t + /@[a-zA-Z_][a-zA-Z_0-9]*@/!b' && cat $tmp/subs.frag) >$tmp/subs-$ac_sed_frag.sed + if test -z "$ac_sed_cmds"; then + ac_sed_cmds="sed -f $tmp/subs-$ac_sed_frag.sed" + else + ac_sed_cmds="$ac_sed_cmds | sed -f $tmp/subs-$ac_sed_frag.sed" + fi + ac_sed_frag=`expr $ac_sed_frag + 1` + ac_beg=$ac_end + ac_end=`expr $ac_end + $ac_max_sed_lines` + fi + done + if test -z "$ac_sed_cmds"; then + ac_sed_cmds=cat + fi +fi # test -n "$CONFIG_FILES" + +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF +for ac_file in : $CONFIG_FILES; do test "x$ac_file" = x: && continue + # Support "outfile[:infile[:infile...]]", defaulting infile="outfile.in". + case $ac_file in + - | *:- | *:-:* ) # input from stdin + cat >$tmp/stdin + ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + *:* ) ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + * ) ac_file_in=$ac_file.in ;; + esac + + # Compute @srcdir@, @top_srcdir@, and @INSTALL@ for subdirectories. + ac_dir=`(dirname "$ac_file") 2>/dev/null || +$as_expr X"$ac_file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$ac_file" : 'X\(//\)[^/]' \| \ + X"$ac_file" : 'X\(//\)$' \| \ + X"$ac_file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$ac_file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. We are building in place. + ac_srcdir=. + if test -z "$ac_top_builddir"; then + ac_top_srcdir=. + else + ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'` + fi ;; + [\\/]* | ?:[\\/]* ) # Absolute path. + ac_srcdir=$srcdir$ac_dir_suffix; + ac_top_srcdir=$srcdir ;; + *) # Relative path. + ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix + ac_top_srcdir=$ac_top_builddir$srcdir ;; +esac + +# Do not use `cd foo && pwd` to compute absolute paths, because +# the directories may not exist. +case `pwd` in +.) ac_abs_builddir="$ac_dir";; +*) + case "$ac_dir" in + .) ac_abs_builddir=`pwd`;; + [\\/]* | ?:[\\/]* ) ac_abs_builddir="$ac_dir";; + *) ac_abs_builddir=`pwd`/"$ac_dir";; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_builddir=${ac_top_builddir}.;; +*) + case ${ac_top_builddir}. in + .) ac_abs_top_builddir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_builddir=${ac_top_builddir}.;; + *) ac_abs_top_builddir=$ac_abs_builddir/${ac_top_builddir}.;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_srcdir=$ac_srcdir;; +*) + case $ac_srcdir in + .) ac_abs_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_srcdir=$ac_srcdir;; + *) ac_abs_srcdir=$ac_abs_builddir/$ac_srcdir;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_srcdir=$ac_top_srcdir;; +*) + case $ac_top_srcdir in + .) ac_abs_top_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_srcdir=$ac_top_srcdir;; + *) ac_abs_top_srcdir=$ac_abs_builddir/$ac_top_srcdir;; + esac;; +esac + + + case $INSTALL in + [\\/$]* | ?:[\\/]* ) ac_INSTALL=$INSTALL ;; + *) ac_INSTALL=$ac_top_builddir$INSTALL ;; + esac + + if test x"$ac_file" != x-; then + { echo "$as_me:$LINENO: creating $ac_file" >&5 +echo "$as_me: creating $ac_file" >&6;} + rm -f "$ac_file" + fi + # Let's still pretend it is `configure' which instantiates (i.e., don't + # use $as_me), people would be surprised to read: + # /* config.h. Generated by config.status. */ + if test x"$ac_file" = x-; then + configure_input= + else + configure_input="$ac_file. " + fi + configure_input=$configure_input"Generated from `echo $ac_file_in | + sed 's,.*/,,'` by configure." + + # First look for the input files in the build tree, otherwise in the + # src tree. + ac_file_inputs=`IFS=: + for f in $ac_file_in; do + case $f in + -) echo $tmp/stdin ;; + [\\/$]*) + # Absolute (can't be DOS-style, as IFS=:) + test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + echo "$f";; + *) # Relative + if test -f "$f"; then + # Build tree + echo "$f" + elif test -f "$srcdir/$f"; then + # Source tree + echo "$srcdir/$f" + else + # /dev/null tree + { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + fi;; + esac + done` || { (exit 1); exit 1; } +_ACEOF +cat >>$CONFIG_STATUS <<_ACEOF + sed "$ac_vpsub +$extrasub +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF +:t +/@[a-zA-Z_][a-zA-Z_0-9]*@/!b +s,@configure_input@,$configure_input,;t t +s,@srcdir@,$ac_srcdir,;t t +s,@abs_srcdir@,$ac_abs_srcdir,;t t +s,@top_srcdir@,$ac_top_srcdir,;t t +s,@abs_top_srcdir@,$ac_abs_top_srcdir,;t t +s,@builddir@,$ac_builddir,;t t +s,@abs_builddir@,$ac_abs_builddir,;t t +s,@top_builddir@,$ac_top_builddir,;t t +s,@abs_top_builddir@,$ac_abs_top_builddir,;t t +s,@INSTALL@,$ac_INSTALL,;t t +" $ac_file_inputs | (eval "$ac_sed_cmds") >$tmp/out + rm -f $tmp/stdin + if test x"$ac_file" != x-; then + mv $tmp/out $ac_file + else + cat $tmp/out + rm -f $tmp/out + fi + +done +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF + +{ (exit 0); exit 0; } +_ACEOF +chmod +x $CONFIG_STATUS +ac_clean_files=$ac_clean_files_save + + +# configure is writing to config.log, and then calls config.status. +# config.status does its own redirection, appending to config.log. +# Unfortunately, on DOS this fails, as config.log is still kept open +# by configure, so config.status won't be able to write to it; its +# output is simply discarded. So we exec the FD to /dev/null, +# effectively closing config.log, so it can be properly (re)opened and +# appended to by config.status. When coming back to configure, we +# need to make the FD available again. +if test "$no_create" != yes; then + ac_cs_success=: + ac_config_status_args= + test "$silent" = yes && + ac_config_status_args="$ac_config_status_args --quiet" + exec 5>/dev/null + $SHELL $CONFIG_STATUS $ac_config_status_args || ac_cs_success=false + exec 5>>config.log + # Use ||, not &&, to avoid exiting from the if with $? = 1, which + # would make configure fail if this is the last instruction. + $ac_cs_success || { (exit 1); exit 1; } +fi + + +echo +echo "Supported devices:" +if test "$DO_PS" != "#"; then echo " PostScript"; fi +if test "$DO_FIG" != "#"; then echo " FIG"; fi +if test "$DO_X11" != "#"; then echo " X11"; fi +if test "$DO_WIN32" != "#"; then echo " Win32"; fi +if test "$DO_GD" != "#"; then echo " GD"; fi + +echo +echo "Unsupported devices:" +if test "$DO_PS" = "#"; then echo " PostScript"; fi +if test "$DO_FIG" = "#"; then echo " FIG"; fi +if test "$DO_X11" = "#"; then echo " X11"; fi +if test "$DO_WIN32" = "#"; then echo " Win32"; fi +if test "$DO_GD" = "#"; then echo " GD"; fi + +echo +echo "Run 'make depend' to create dependencies." +echo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure.in new file mode 100755 index 00000000..f750225b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/configure.in @@ -0,0 +1,139 @@ + +# +# Check for one project file +# +AC_INIT(src/g2_device.c) + +PRODUCT=g2 + + +# +# check cannonical system name, +# and set options for shared libraries (black magic) +# +AC_CANONICAL_HOST +case "$host" in + *-linux*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared -soname libg2.so.0' + LD_SHARED_OPT='' + LD_SHARED_EXT='so.0.$(G2_VERSION)' + AC_DEFINE(LINUX);; + *-aix*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-bM:SRE -bnoentry -bexpall' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + AC_DEFINE(AIX);; + *-osf*) + LD_SHARED='ld' + LD_SHARED_FLAGS='-shared' + LD_SHARED_OPT='$(LDFLAGS) -lc' + LD_SHARED_EXT='so' + AC_DEFINE(OSF);; + *) + LD_SHARED_EXT='so' + AC_DEFINE(UNIX);; +esac + +AC_SUBST(LD_SHARED) +AC_SUBST(LD_SHARED_FLAGS) +AC_SUBST(LD_SHARED_OPT) +AC_SUBST(LD_SHARED_EXT) + +# +# check C compiler, preprocesor, etc. +# +AC_PROG_CC +AC_PROG_CPP +AC_PROG_CXX +AC_PROG_RANLIB +AC_PROG_INSTALL +AC_CHECK_PROG(FIND, find, find, :) +AC_CHECK_PROG(MAKEDEPEND, makedepend, makedepend, :) +AC_CHECK_LIB(dl, dlopen, have_dl=yes, have_dl=no) + + +# +# Try to locate the X Window System include files and libraries +# and add /usr/local to include and lib path and add -lm (for testing) +# +AC_PATH_XTRA +CFLAGS="$CFLAGS $X_CFLAGS -I/usr/local/include" +LDFLAGS="$LDFLAGS $X_LIBS -L/usr/local/lib" + + +DO_PS='#' +DO_FIG='#' +DO_X11='#' +DO_GD='#' +DO_WIN32='#' + + +# +# check supported devices +# +AC_CHECK_LIB(m,main,DO_PS='';DO_FIG='';LDFLAGS="$LDFLAGS -lm";AC_DEFINE(DO_PS) AC_DEFINE(DO_FIG),break) +AC_CHECK_LIB(X11, main, DO_X11='';LDFLAGS="$LDFLAGS -lX11";AC_DEFINE(DO_X11)) +AC_CHECK_LIB(gd, main, have_gd=yes, have_gd=no) +if test "$have_gd" = yes +then + LDFLAGS="$LDFLAGS -lgd" + AC_CHECK_FUNC(gdImagePng, DO_GD='';AC_DEFINE(DO_GD)) +fi + +# +# handling cygwin environment (and gd for cygwin == bgd) +# +AC_CYGWIN +if test "$CYGWIN" = yes +then + LDFLAGS="$LDFLAGS -L/lib/w32api" + AC_CHECK_LIB(gdi32, main, DO_WIN32='';LDFLAGS="$LDFLAGS -lgdi32";AC_DEFINE(DO_WIN32)) + AC_CHECK_LIB(bgd, main, have_bgd=yes, have_bgd=no) + if test "$have_bgd" = yes + then + LDFLAGS="$LDFLAGS -lbgd" + AC_CHECK_FUNC(gdImagePng, DO_GD='';AC_DEFINE(DO_GD)) + fi +fi + +# +# Declare variables which we want substituted in the Makefile.in's +# +AC_SUBST(DO_PS) +AC_SUBST(DO_FIG) +AC_SUBST(DO_X11) +AC_SUBST(DO_WIN32) +AC_SUBST(DO_GD) + +AC_HEADER_STDC +AC_CHECK_HEADERS(limits.h) + + + +# +# finally create makefiles using Makefile.in +# +echo +AC_OUTPUT(Makefile demo/Makefile g2_perl/Makefile.PL) + +echo +echo "Supported devices:" +if test "$DO_PS" != "#"; then echo " PostScript"; fi +if test "$DO_FIG" != "#"; then echo " FIG"; fi +if test "$DO_X11" != "#"; then echo " X11"; fi +if test "$DO_WIN32" != "#"; then echo " Win32"; fi +if test "$DO_GD" != "#"; then echo " GD"; fi + +echo +echo "Unsupported devices:" +if test "$DO_PS" = "#"; then echo " PostScript"; fi +if test "$DO_FIG" = "#"; then echo " FIG"; fi +if test "$DO_X11" = "#"; then echo " X11"; fi +if test "$DO_WIN32" = "#"; then echo " Win32"; fi +if test "$DO_GD" = "#"; then echo " GD"; fi + +echo +echo "Run 'make depend' to create dependencies." +echo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Repository new file mode 100755 index 00000000..c5ef7f81 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/demo/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Entries new file mode 100755 index 00000000..b75535d9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Entries @@ -0,0 +1,21 @@ +D/CVS//// +/Makefile.in/1.1/Tue Jun 14 20:44:20 2005// +/demo_cpp.cpp/1.1/Tue Apr 20 20:18:09 2004// +/demo_f.f/1.1/Tue Apr 17 20:16:38 2001// +/descrip.mms/1.1/Thu Nov 22 00:15:59 2001// +/g2_anim.c/1.1/Fri Apr 16 01:20:04 2004// +/g2_arc.c/1.1/Tue Feb 22 22:16:18 2005// +/g2_splines_demo.c/1.1/Sun Feb 29 23:47:46 2004// +/g2_test.c/1.1/Sat Apr 3 22:57:15 2004// +/g2_test.f/1.1/Thu Mar 4 23:13:36 2004// +/handles.c/1.1/Tue Jun 14 20:44:20 2005// +/penguin.c/1.1/Mon Jan 18 10:56:51 1999// +/penguin.inc/1.1/Thu Mar 4 23:13:36 2004// +/pointer.c/1.1/Tue Apr 17 20:16:38 2001// +/simple_FIG.c/1.1/Thu Apr 1 22:29:34 2004// +/simple_PS.c/1.1/Tue Apr 17 20:16:38 2001// +/simple_X11.c/1.1/Tue Apr 17 20:16:38 2001// +/simple_gd.c/1.1/Tue Apr 17 20:16:38 2001// +/simple_win32.c/1.1/Tue Sep 3 04:10:23 2002// +/xlink.opt/1.1/Mon Jan 18 10:56:51 1999// +/Makefile/1.1/Fri Aug 5 10:17:46 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Repository new file mode 100755 index 00000000..6762ec27 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/demo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile new file mode 100755 index 00000000..334e4c8e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile @@ -0,0 +1,87 @@ +# +# +# Makefile for g2_library (demo) +# +# + + +CC = gcc +CXX = g++ +##Linux +F77 = g77 +CPP = /lib/cpp + +##OSF +#F77 = f77 +#F77_FLAGS=-i8 + +##AIX +#F77 = xlf +#CPP = /usr/ccs/lib/cpp + +##IRIX +#F77 = f77 -n32 +#CPP = /lib/cpp -P -DFORTRAN + +CFLAGS = -I../src -I../src/X11 -I../src/PS -I../src/Win32 -I../src/GD -I../src/FIG -g -O2 -I/usr/X11R6/include -I/usr/local/include -DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 +CXXFLAGS = -I../src -I../src/X11 -I../src/PS -I../src/Win32 -I../src/GD/ -I../src/FIG -g -O2 -DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 +LDFLAGS = -L.. -lg2 -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd + +DEMO_PS = simple_PS +DEMO_FIG = simple_FIG +DEMO_X11 = simple_X11 pointer handles +DEMO_GD = simple_gd +#DEMO_WIN32 = simple_win32 + + +DEMO = g2_test g2_arc g2_splines_demo demo_cpp $(DEMO_PS) $(DEMO_FIG) $(DEMO_X11) $(DEMO_GD) $(DEMO_WIN32) + +all: $(DEMO) + +demo: $(DEMO) + + +g2_test: g2_test.c + $(CC) $(CFLAGS) g2_test.c $(LDFLAGS) -o $@ + +g2_arc: g2_arc.c + $(CC) $(CFLAGS) g2_arc.c $(LDFLAGS) -o $@ + +g2_splines_demo: g2_splines_demo.c + $(CC) $(CFLAGS) g2_splines_demo.c $(LDFLAGS) -o $@ + +simple_PS: simple_PS.c + $(CC) $(CFLAGS) simple_PS.c $(LDFLAGS) -o $@ + +simple_FIG: simple_FIG.c + $(CC) $(CFLAGS) simple_FIG.c $(LDFLAGS) -o $@ + +simple_X11: simple_X11.c + $(CC) $(CFLAGS) simple_X11.c $(LDFLAGS) -o $@ + +simple_win32: simple_win32.c + $(CC) $(CFLAGS) simple_win32.c $(LDFLAGS) -lkernel32 -lgdi32 -luser32 -lcomdlg32 -o $@ + +pointer: pointer.c + $(CC) $(CFLAGS) pointer.c $(LDFLAGS) -o $@ + +handles: handles.c + $(CC) $(CFLAGS) handles.c $(LDFLAGS) -o $@ + +simple_gd: simple_gd.c + $(CC) $(CFLAGS) simple_gd.c $(LDFLAGS) -o $@ + +demo_cpp: demo_cpp.cpp + $(CXX) $(CXXFLAGS) demo_cpp.cpp $(LDFLAGS) -o $@ + +demo_f: demo_f.f + $(F77) $(F77_FLAGS) demo_f.f $(LDFLAGS) -o $@ + +g2testf: g2_test.f + $(CPP) -DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 -E g2_test.f > g2testf.f + $(F77) g2testf.f $(LDFLAGS) -o g2testf + +clean: + -rm $(DEMO) g2testf g2testf.f demo_f *~ core *.ps *.fig *.eps *.png *.jpg *.fig.bak + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile.in new file mode 100755 index 00000000..8a57d8d3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/Makefile.in @@ -0,0 +1,87 @@ +# +# +# Makefile for g2_library (demo) +# +# + + +CC = @CC@ +CXX = @CXX@ +##Linux +F77 = g77 +CPP = /lib/cpp + +##OSF +#F77 = f77 +#F77_FLAGS=-i8 + +##AIX +#F77 = xlf +#CPP = /usr/ccs/lib/cpp + +##IRIX +#F77 = f77 -n32 +#CPP = /lib/cpp -P -DFORTRAN + +CFLAGS = -I../src -I../src/X11 -I../src/PS -I../src/Win32 -I../src/GD -I../src/FIG @CFLAGS@ @DEFS@ +CXXFLAGS = -I../src -I../src/X11 -I../src/PS -I../src/Win32 -I../src/GD/ -I../src/FIG @CXXFLAGS@ @DEFS@ +LDFLAGS = -L.. -lg2 @LDFLAGS@ + +@DO_PS@DEMO_PS = simple_PS +@DO_FIG@DEMO_FIG = simple_FIG +@DO_X11@DEMO_X11 = simple_X11 pointer handles +@DO_GD@DEMO_GD = simple_gd +@DO_WIN32@DEMO_WIN32 = simple_win32 + + +DEMO = g2_test g2_arc g2_splines_demo demo_cpp $(DEMO_PS) $(DEMO_FIG) $(DEMO_X11) $(DEMO_GD) $(DEMO_WIN32) + +all: $(DEMO) + +demo: $(DEMO) + + +g2_test: g2_test.c + $(CC) $(CFLAGS) g2_test.c $(LDFLAGS) -o $@ + +g2_arc: g2_arc.c + $(CC) $(CFLAGS) g2_arc.c $(LDFLAGS) -o $@ + +g2_splines_demo: g2_splines_demo.c + $(CC) $(CFLAGS) g2_splines_demo.c $(LDFLAGS) -o $@ + +simple_PS: simple_PS.c + $(CC) $(CFLAGS) simple_PS.c $(LDFLAGS) -o $@ + +simple_FIG: simple_FIG.c + $(CC) $(CFLAGS) simple_FIG.c $(LDFLAGS) -o $@ + +simple_X11: simple_X11.c + $(CC) $(CFLAGS) simple_X11.c $(LDFLAGS) -o $@ + +simple_win32: simple_win32.c + $(CC) $(CFLAGS) simple_win32.c $(LDFLAGS) -lkernel32 -lgdi32 -luser32 -lcomdlg32 -o $@ + +pointer: pointer.c + $(CC) $(CFLAGS) pointer.c $(LDFLAGS) -o $@ + +handles: handles.c + $(CC) $(CFLAGS) handles.c $(LDFLAGS) -o $@ + +simple_gd: simple_gd.c + $(CC) $(CFLAGS) simple_gd.c $(LDFLAGS) -o $@ + +demo_cpp: demo_cpp.cpp + $(CXX) $(CXXFLAGS) demo_cpp.cpp $(LDFLAGS) -o $@ + +demo_f: demo_f.f + $(F77) $(F77_FLAGS) demo_f.f $(LDFLAGS) -o $@ + +g2testf: g2_test.f + $(CPP) @DEFS@ -E g2_test.f > g2testf.f + $(F77) g2testf.f $(LDFLAGS) -o g2testf + +clean: + -rm $(DEMO) g2testf g2testf.f demo_f *~ core *.ps *.fig *.eps *.png *.jpg *.fig.bak + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_cpp.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_cpp.cpp new file mode 100755 index 00000000..c78480a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_cpp.cpp @@ -0,0 +1,40 @@ +#include +#include +#include +#include + +/* A very simple example to demonstrate g2 in a C++ environment */ + + +class Circle +{ +public: + Circle(int d, double x, double y, double r) + : _d(d), _x(x), _y(y), _r(r) + { + g2_circle(d, x, y, r); + g2_flush(d); + } + + void Fill() + { + g2_filled_circle(_d, _x, _y, _r); + g2_flush(_d); + } +private: + int _d; + double _x, _y, _r; +}; + + +int main(int argc, char *argv[]) +{ + int d; + d=g2_open_PS("demo_cpp.ps", g2_A4, g2_PS_port); + Circle c(d, 150, 150, 25); + c.Fill(); + Circle c2(d, 150, 175, 25); + g2_close(d); + std::cout << "demo_cpp.ps generated\n"; + return 0; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_f.f b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_f.f new file mode 100755 index 00000000..599826b0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/demo_f.f @@ -0,0 +1,59 @@ +c +c Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +c This file is part of the g2 library +c +c This library is free software; you can redistribute it and/or +c modify it under the terms of the GNU Lesser General Public +c License as published by the Free Software Foundation; either +c version 2.1 of the License, or (at your option) any later version. +c +c This library is distributed in the hope that it will be useful, +c but WITHOUT ANY WARRANTY; without even the implied warranty of +c MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +c Lesser General Public License for more details. +c +c You should have received a copy of the GNU Lesser General Public +c License along with this library; if not, write to the Free Software +c Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +c + real demo_f + real a, b + real d, d1, d2 + real color + + d=g2_open_vd() + write (6,*) d + d1=g2_open_X11(100.0, 100.0) + write (6,*) d1 + d2=g2_open_PS('demo_f.ps', 4.0, 1.0) + write (6,*) d2 + + call g2_attach(d, d1) + call g2_attach(d, d2) + + call g2_plot(d, 50.0, 50.0) + call g2_arc(d, 50.0, 50.0, 30.0, 20.0, 45.0, 180.0) + + color=g2_ink(d1, 1.0, 0.0, 0.0) + call g2_pen(d1, color) + write (6,*) color + call g2_string(d1, 15.0, 75.0, 'TEST (Window)') + + color=g2_ink(d2, 0.0, 1.0, 0.0) + call g2_pen(d2, color) + write (6,*) color + call g2_string(d2, 15.0, 75.0, 'TEST (File)') + + call g2_pen(d, 1.0) + call g2_circle(d, 20.0, 20.0, 10.0) + call g2_string(d, 20.0, 20.0, 'All devices!') + call g2_flush(d) + + call g2_close(d2) + + read (*,*) a + + stop + end + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/descrip.mms b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/descrip.mms new file mode 100755 index 00000000..d89ac9b0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/descrip.mms @@ -0,0 +1,57 @@ +! +! VMS descrip.mms for g2 demos +! + +! +! Change these pointers to the correct location of libGD,libpng, etc +! +GD_LIBS = [.-.-.-.GD-1_8_4]libgd.olb/lib,[.-.-.-.lpng120]libpng.olb/lib,[.-.-.-.ZLIB]libz.olb/lib,[.-.-.-.JPEG-6B]libjpeg.olb/lib + +.IFDEF debug +CC_FLAGS = /noopt/debug/nolist/warnings \ + /include_directory=([-.src],[-.src.X11],[-.src.PS],[-.src.GD]) \ + /define=(DO_PS, DO_X11, DO_GD) +LINK_FLAGS = +.ELSE +CC_FLAGS = /nolist/warnings \ + /include_directory=([-.src],[-.src.X11],[-.src.PS],[-.src.GD]) \ + /define=(DO_PS, DO_X11, DO_GD) +LINK_FLAGS = +.ENDIF + +! +! Rules +! +.c.obj : ; cc $(CC_FLAGS)/obj=$(mms$target) $(mms$source) + + +! +! exe files +! +all : g2_test.exe, simple_X11.exe, simple_PS.exe + @ write sys$output "Demo files compiled." + + +g2_test.exe : g2_test.obj + link $(LINK_FLAGS)/exe=g2_test.exe g2_test.obj, \ + [-]g2.olb/lib, []xlink.opt/opt, $(GD_LIBS) + +simple_X11.exe : simple_X11.obj + link $(LINK_FLAGS)/exe=simple_X11.exe simple_X11.obj, \ + [-]g2.olb/lib, []xlink.opt/opt + +simple_PS.exe : simple_PS.obj + link $(LINK_FLAGS)/exe=simple_PS.exe simple_PS.obj, [-]g2.olb/lib + + + +clean : + delete *.exe;* , *.obj;* , *.olb;* + + +! +! Dependencies +! +g2_test.obj : g2_test.c +simple_X11.obj : simple_X11.c +simple_PS.obj : simple_PS.c diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_anim.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_anim.c new file mode 100755 index 00000000..5116f119 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_anim.c @@ -0,0 +1,60 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + + +#define N 300 +#define W 400 +#define H 400 + +int main() +{ + int d; + int x[N]; + int y[N]; + int c[N]; + int i,t; + + d=g2_open_win32(W, H, "simple_animation", 0); + g2_set_auto_flush(d,0); + + for (i=0;i +#include + +#ifdef DO_PS +#include +#endif +#ifdef DO_FIG +#include +#endif +#ifdef DO_X11 +#include +#endif +#ifdef DO_GD +#include +#endif +#ifdef DO_WIN32 +#include +#endif +#ifdef DO_WMF32 +#include +#endif + +#define maxdev 10 + +int main() +{ + int i, j; + int d, dev[maxdev]={-1, -1, -1, -1, -1,-1, -1, -1, -1, -1}; + int ndev=0; + char str[256]; + double y; + + printf("\nG2_VERSION %s\n", G2_VERSION); + + d=g2_open_vd(); /* open virtual device */ + + printf("Adding.."); + +#ifdef DO_PS + printf("..PS"); + dev[ndev]=g2_open_PS("g2_arc.ps", g2_A4, g2_PS_land); + g2_attach(d, dev[ndev]); + ndev++; + + printf("..EPSF"); + dev[ndev]=g2_open_EPSF("g2_arc.eps"); + g2_attach(d, dev[ndev]); + ndev++; + printf("..EPSF_CLIP"); + dev[ndev]=g2_open_EPSF_CLIP("g2_arc_clip.eps",400,400); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_FIG + printf("..FIG"); + dev[ndev]=g2_open_FIG("g2_arc.fig"); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_X11 + printf("..X11"); + dev[ndev]=g2_open_X11(400,400); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_GD + printf("..GD(png)"); + dev[ndev]=g2_open_gd("g2_arc.png", 400, 400,g2_gd_png); + g2_attach(d, dev[ndev]); + ndev++; + printf("..GD(jpeg)"); + dev[ndev]=g2_open_gd("g2_arc.jpg", 400, 400,g2_gd_jpeg); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_WIN32 + printf("..WIN32"); + dev[ndev]=g2_open_win32(400, 400,"g2_arc",0); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_WMF32 + printf("..WMF32"); + dev[ndev]=g2_open_win32(775, 575,"g2_arc.emf",1); + g2_attach(d, dev[ndev]); + ndev++; +#endif + g2_set_auto_flush(d,0); + + printf("\n"); + + g2_string(d,10, 50,"90,90"); + g2_string(d,10,100,"90,360"); + g2_string(d,10,150,"90,0"); + g2_string(d,10,200,"360,90"); + g2_string(d,10,250,"-45,45"); + g2_string(d,10,300,"-45,-315"); + g2_string(d,10,350,"-495,-405"); + + g2_arc(d, 100, 50, 45, 25, 90, 90); + g2_arc(d, 100, 100, 45, 25, 90, 360); + g2_arc(d, 100, 150, 45, 25, 90, 0); + g2_arc(d, 100, 200, 45, 25, 360, 90); + g2_arc(d, 100, 250, 45, 25, -45, 45); + g2_arc(d, 100, 300, 45, 25, -45, -315); + g2_arc(d, 100, 350, 45, 25, -495, -405); + + g2_filled_arc(d, 100, 50, 40, 20, 90, 90); + g2_filled_arc(d, 100, 100, 40, 20, 90, 360); + g2_filled_arc(d, 100, 150, 40, 20, 90, 0); + g2_filled_arc(d, 100, 200, 40, 20, 360, 90); + g2_filled_arc(d, 100, 250, 40, 20, -45, 45); + g2_filled_arc(d, 100, 300, 40, 20, -45, -315); + g2_filled_arc(d, 100, 350, 40, 20, -495, -405); + + + + g2_string(d,320, 50,"0,0"); + g2_string(d,320,100,"360,90"); + g2_string(d,320,150,"0,90"); + g2_string(d,320,200,"90,360"); + g2_string(d,320,250,"45,-45"); + g2_string(d,320,300,"-315,-45"); + g2_string(d,320,350,"-405,-495"); + + g2_arc(d, 250, 50, 45, 25, 0, 0); + g2_arc(d, 250, 100, 45, 25, 360, 90); + g2_arc(d, 250, 150, 45, 25, 0, 90); + g2_arc(d, 250, 200, 45, 25, 90, 360); + g2_arc(d, 250, 250, 45, 25, 45, -45); + g2_arc(d, 250, 300, 45, 25, -315, -45); + g2_arc(d, 250, 350, 45, 25, -405, -495); + + g2_filled_arc(d, 250, 50, 40, 20, 90, 90); + g2_filled_arc(d, 250, 100, 40, 20, 360, 90); + g2_filled_arc(d, 250, 150, 40, 20, 0, 90); + g2_filled_arc(d, 250, 200, 40, 20, 90, 360); + g2_filled_arc(d, 250, 250, 40, 20, 45, -45); + g2_filled_arc(d, 250, 300, 40, 20, -315, -45); + g2_filled_arc(d, 250, 350, 40, 20, -405, -495); + + g2_flush(d); + printf("\nDone.\n[Enter]\n"); + getchar(); + g2_close(d); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_splines_demo.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_splines_demo.c new file mode 100755 index 00000000..d02b152b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_splines_demo.c @@ -0,0 +1,143 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +/* + * g2_splines_demo.c + * 06/16/99 + */ + +#include + +#include +#ifdef DO_PS +#include +#endif +#ifdef DO_X11 +#include +#endif +#ifdef DO_GD +#include +#endif +#ifdef DO_WIN32 +#include +#endif +#ifdef DO_WMF32 +#include +#endif + + + +#define n 14 +#define o 60 +#define tn 0.6 + +#define X11 0 +#define PS 1 +#define GD 2 + +int otp=X11; + +int id=-1 ; /* default output device */ + + +void curves() +{ + int i; + double points[(2*n)]; + double dy[n] = { 10., 280., 140., 200., 60., 120., 380., + 500., 480., 400., 220., 180., 260., 340.}; + + for (i = 0; i < n; i++) { + points[(i+i)] = (i*o)+20.; /* from 20 to 800 (20+(13*60)) */ + points[(i+i+1)] = dy[i]; + } + g2_pen(id, 1); + g2_poly_line(id, n, points); + g2_pen(id, 3); + g2_spline(id, n, points, o); + g2_pen(id, 7); + g2_b_spline(id, n, points, o); + g2_pen(id, 10); + g2_raspln(id, n, points, tn); + g2_pen(id, 19); + g2_para_3(id, n, points); + g2_pen(id, 22); + g2_para_5(id, n, points); +} + +void axes() +{ + g2_line(id, 5, 300, 810, 300); + g2_line(id, 400, 5, 400, 560); +} + +void draw() +{ + g2_rectangle(id, 5, 5, 810, 560); /* window: 815 x 565 */ + axes(); + curves(); +} + +int main(int argc, char *argv[]) +{ + int dev[5]={-1, -1, -1, -1, -1}; + + id=g2_open_vd(); /* open virtual device */ + + printf("\nAdding.."); + +#ifdef DO_PS + printf("..PS"); + dev[0]=g2_open_PS("g2_splines_demo.ps", g2_A4, g2_PS_land); + g2_attach(id, dev[0]); +#endif +#ifdef DO_X11 + printf("..X11"); + dev[1]=g2_open_X11(850, 600); + g2_attach(id, dev[1]); +#endif +#ifdef DO_GD + printf("..GD"); + dev[2]=g2_open_gd("g2_splines_demo.png", 850, 600, g2_gd_png); + g2_attach(id, dev[2]); +#endif +#ifdef DO_WIN32 + printf("..WIN32"); + dev[3]=g2_open_win32(850, 600,"g2_splines_demo",0); + g2_set_auto_flush(dev[3],0); + g2_attach(id, dev[3]); +#endif +#ifdef DO_WMF32 + printf("..WMF32"); + dev[4]=g2_open_win32(850, 600,"g2_splines_demo.emf",1); + g2_set_auto_flush(dev[3],0); + g2_attach(id, dev[4]); +#endif + + g2_set_auto_flush(id,0); + g2_set_coordinate_system(id, 12, 15, 1., 1.); + + draw(); + g2_flush(id); + if (otp==X11) { + printf("\nDone.\n[Enter]\n"); + getchar(); + } + g2_close(id); + return 0; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.c new file mode 100755 index 00000000..850eda67 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.c @@ -0,0 +1,254 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ + +#include +#include + +#ifdef DO_PS +#include +#endif +#ifdef DO_FIG +#include +#endif +#ifdef DO_X11 +#include +#endif +#ifdef DO_GD +#include +#endif +#ifdef DO_WIN32 +#include +#endif +#ifdef DO_WMF32 +#include +#endif + +#define maxdev 10 + +int main() +{ + int i, j; + int d, dev[maxdev]={-1, -1, -1, -1, -1,-1, -1, -1, -1, -1}; + int ndev=0; + char str[256]; + double pts[10]; + double y; +#include "penguin.c" + + printf("\nG2_VERSION %s\n", G2_VERSION); + + d=g2_open_vd(); /* open virtual device */ + + printf("Adding.."); + +#ifdef DO_PS + printf("..PS"); + dev[ndev]=g2_open_PS("g2_test.ps", g2_A4, g2_PS_land); + g2_attach(d, dev[ndev]); + ndev++; + + printf("..EPSF"); + dev[ndev]=g2_open_EPSF("g2_test.eps"); + g2_attach(d, dev[ndev]); + ndev++; + printf("..EPSF_CLIP"); + dev[ndev]=g2_open_EPSF_CLIP("g2_test_clip.eps",200,200); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_FIG + printf("..FIG"); + dev[ndev]=g2_open_FIG("g2_test.fig"); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_X11 + printf("..X11"); + dev[ndev]=g2_open_X11(775, 575); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_GD + printf("..GD(png)"); + dev[ndev]=g2_open_gd("g2_test.png", 775, 575,g2_gd_png); + g2_attach(d, dev[ndev]); + ndev++; + printf("..GD(jpeg)"); + dev[ndev]=g2_open_gd("g2_test.jpg", 775, 575,g2_gd_jpeg); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_WIN32 + printf("..WIN32"); + dev[ndev]=g2_open_win32(775, 575,"g2_test",0); + g2_attach(d, dev[ndev]); + ndev++; +#endif +#ifdef DO_WMF32 + printf("..WMF32"); + dev[ndev]=g2_open_win32(775, 575,"g2_test.emf",1); + g2_attach(d, dev[ndev]); + ndev++; +#endif + g2_set_auto_flush(d,0); + + printf("\n"); + + /* g2_set_coordinate_system(d, 775, 575, -0.75, -1.0); */ + + for(i=0;i<27;i++) { + g2_pen(d, i); + g2_filled_circle(d, i*20+10, 10, 10); + g2_pen(d, 1); + g2_circle(d, i*20+10, 10, 10); + sprintf(str, "%d", i); + g2_string(d, i*20+7, 21, str); + } + + for(j=0;j=0) + for(i=0;i<=64;i++) { + g2_move(dev[j], 2*i+575, 5); + g2_pen(dev[j], g2_ink(dev[j], i/64., 0, 0)); + g2_line_r(dev[j], 0, 20); + g2_pen(dev[j], g2_ink(dev[j], 0, i/64., 0)); + g2_line_r(dev[j], 10, 20); + g2_pen(dev[j], g2_ink(dev[j], 0, 0, i/64.)); + g2_line_r(dev[j], -10, 20); + } + + g2_pen(d, 1); + g2_line(d, 200, 50, 350, 50); + g2_line(d, 200, 48, 350, 48); + g2_line(d, 200, 46, 350, 46); + g2_line(d, 200, 46, 200, 75); + g2_line(d, 198, 46, 198, 75); + g2_line(d, 196, 46, 196, 75); + g2_string(d, 200, 50, "012abcABC#())(\\-+~*!$%&"); + + g2_pen(d, 1); + for(i=1;i<25;i++) { + g2_line(d, 15, i*20+50, 15, i*20+50+i); + g2_set_font_size(d, 12); + sprintf(str, "%2d:", i); + g2_string(d, 20, i*20+50, str); + g2_set_font_size(d, i); + g2_string(d, 40, i*20+50, "hello, world"); + } + + g2_plot(d, 150, 70); + g2_line(d, 147, 68, 153, 68); + + y=100; + g2_line(d, 120, y, 170, y+50); + g2_triangle(d, 150, y, 250, y, 200, y+50); + g2_rectangle(d, 300, y, 400, y+50); + g2_circle(d, 450, y+25, 25); + g2_ellipse(d, 550, y+25, 45, 25); + g2_arc(d, 650, y+25, 25, 45, 90, 360); + + pts[0]=4; + pts[1]=4; + g2_set_dash(d, 2, pts); + g2_line(d, 120+5, y, 170+5, y+50); + g2_triangle(d, 150+10, y+4, 250-10, y+4, 200, y+50-5); + g2_rectangle(d, 305, y+5, 395, y+50-5); + g2_circle(d, 450, y+25, 20); + g2_ellipse(d, 550, y+25, 40, 20); + g2_arc(d, 650, y+25, 20, 40, 90, 360); + g2_set_dash(d, 0, NULL); + + y=200; + g2_filled_triangle(d, 150, y, 250, y, 200, y+50); + g2_filled_rectangle(d, 300, y, 400, y+50); + g2_filled_circle(d, 450, y+25, 25); + g2_filled_ellipse(d, 550, y+25, 45, 25); + g2_filled_arc(d, 650, y+25, 25, 45, 90, 360); + + + y=300; + pts[0]=150; pts[1]=y; + pts[2]=175; pts[3]=y+100; + pts[4]=200; pts[5]=y; + pts[6]=225; pts[7]=y+100; + pts[8]=250; pts[9]=y; + g2_poly_line(d, 5, pts); + g2_pen(d, 19); + g2_b_spline(d, 5, pts, 20); + g2_pen(d, 1); + + pts[0]=300; pts[1]=y; + pts[2]=350; pts[3]=y; + pts[4]=375; pts[5]=y+50; + pts[6]=325; pts[7]=y+90; + pts[8]=275; pts[9]=y+50; + g2_polygon(d, 5, pts); + + pts[0]=450; pts[1]=y; + pts[2]=500; pts[3]=y; + pts[4]=525; pts[5]=y+50; + pts[6]=475; pts[7]=y+90; + pts[8]=425; pts[9]=y+50; + g2_filled_polygon(d, 5, pts); + + + g2_image(d, 55., 50., 53, 62, penguin); + g2_image(d, 75., 130., 53, 62, penguin); + g2_pen(d, 1); + + g2_line(d, 225, 448, 200+19*25, 448); + for(i=1;i<20;i++) { + g2_pen(d,i+1); + g2_set_line_width(d, i); + g2_move(d, 200+i*25, 450); + g2_line_to(d, 200+i*25, 550); + } + g2_pen(d,1); + + g2_set_line_width(d, 5); + for(i=1;i<10;i++) { + pts[0]=1*i; + pts[1]=2*i; + pts[2]=3*i; + g2_set_dash(d, 3, pts); + g2_line(d, 550, 300+i*8, 750, 350+i*8); + } + + g2_set_dash(d, 0, NULL); + g2_set_line_width(d, 4); + g2_arc(d, 740, 180, 25, 100, -45+15, -45-15); + g2_arc(d, 740, 180, 20, 95, -45-15, -45+15); + g2_filled_arc(d, 740, 180, 12, 50, -45+15, -45-15); + + g2_set_line_width(d, 1); + g2_circle(d, 400, 400, 20); + g2_ellipse(d, 400, 400, 25, 25); + g2_arc(d, 400, 400, 30, 30, 0, 360); + + g2_flush(d); + printf("\nDone.\n[Enter]\n"); + getchar(); + g2_close(d); + return 0; +} + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.f b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.f new file mode 100755 index 00000000..b15712c7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/g2_test.f @@ -0,0 +1,210 @@ +c +c Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +c This file is part of the g2 library +c +c This library is free software; you can redistribute it and/or +c modify it under the terms of the GNU Lesser General Public +c License as published by the Free Software Foundation; either +c version 2.1 of the License, or (at your option) any later version. +c +c This library is distributed in the hope that it will be useful, +c but WITHOUT ANY WARRANTY; without even the implied warranty of +c MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +c Lesser General Public License for more details. +c +c You should have received a copy of the GNU Lesser General Public +c License along with this library; if not, write to the Free Software +c Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +c + +c +c This file will be processed by cpp, the outpu g2testf.f is feeded into fortran compiler +c See Makefile for details. +c + +c program main +c implicit none + integer ndev, i, j + real d, c, dev(0:10) + character str*256 + real pts(0:10) + real y + include 'penguin.inc' +c integer image(64) +c data image/ +c & 0, 0, 2, 2, 2, 2, 0, 0, +c & 0, 2, 0, 0, 0, 0, 2, 0, +c & 2, 0, 3, 0, 0, 3, 0, 2, +c & 2, 0, 0, 0, 0, 0, 0, 2, +c & 2, 3, 0, 0, 0, 0, 3, 2, +c & 2, 0, 3, 3, 3, 3, 0, 2, +c & 0, 2, 0, 0, 0, 0, 2, 0, +c & 0, 0, 2, 2, 2, 2, 0, 0 / +c /*open virtual device */ + d=g2_open_vd() + print*,"Adding.. VD=", d + ndev = 1 + +#ifdef DO_PS + dev(ndev)=g2_open_ps('g2testf.ps', 4., 0.) + print*,"..PS=",dev(ndev) + call g2_attach(d, dev(ndev)) + ndev = ndev + 1 +#endif +#ifdef DO_X11 + dev(ndev)=g2_open_x11(775., 575.) + print*,"..X11=",dev(ndev) + call g2_attach(d,dev(ndev)) + ndev = ndev + 1 +#endif +#ifdef DO_GD + str='g2testf.png' + str(12:12)=char(0) + dev(ndev)=g2_open_gd(str, 775., 575., 0.) + print*,"..GD=",dev(ndev) + call g2_attach(d,dev(ndev)) + ndev = ndev + 1 +#endif + call g2_set_auto_flush(d,0.) + +c call g2_set_coordinate_system(d, 775., 575., -0.75, -1.0) + + do i=0,27 + call g2_pen(d, float(i)) + call g2_filled_circle(d, float(i*20+10), 10., 10.) + call g2_pen(d, 1.) + call g2_circle(d, float(i*20+10), 10., 10.) + write(str(1:4),'(i3,a1)') i,char(0) + call g2_string(d, float(i*20+7), 21., str(1:4)) + enddo + + do j=1,ndev + if(dev(j).gt.0) then + do i=0,64 + call g2_move(dev(j), float(2*i+575), 5.) + c = g2_ink(dev(j), float(i)/64., 0., 0.) + call g2_pen(dev(j), c) + call g2_line_r(dev(j), 0., 20.) + c = g2_ink(dev(j), 0., float(i)/64., 0.) + call g2_pen(dev(j), c ) + call g2_line_r(dev(j), 10., 20.) + c = g2_ink(dev(j), 0., 0., float(i)/64.) + call g2_pen(dev(j), c) + call g2_line_r(dev(j), -10., 20.) + enddo + endif + enddo + call g2_pen(d, 1.) + call g2_line(d, 200., 50., 350., 50.) + call g2_line(d, 200., 48., 350., 48.) + call g2_line(d, 200., 46., 350., 46.) + call g2_line(d, 200., 46., 200., 75.) + call g2_line(d, 198., 46., 198., 75.) + call g2_line(d, 196., 46., 196., 75.) + str="012abcABC#())(\\-+~*!$%&"//char(0) + call g2_string(d, 200., 50., str) + + call g2_pen(d, 1.) + do i=1,25 + call g2_line(d, 15., float(i*20+50), 15., float(i*20+50+i)) + call g2_set_font_size(d, 12.) + write(str(1:3),'(i2,a1)') i,char(0) + call g2_string(d, 20., float(i*20+50), str) + call g2_set_font_size(d, float(i)) + str='Hello, world!'//char(0) + call g2_string(d, 40., float(i*20+50), str) + enddo + + + call g2_plot(d, 150., 70.) + call g2_line(d, 147., 68., 153., 68.) + + y=100. + call g2_line(d, 100., y, 150., y+50.) + call g2_triangle(d, 150., y, 250., y, 200., y+50.) + call g2_rectangle(d, 300., y, 400., y+50.) + call g2_circle(d, 450., y+25., 25.) + call g2_ellipse(d, 550., y+25., 45., 25.) + call g2_arc(d, 650., y+25., 25., 45., 90., 360.) + + y=200. + call g2_filled_triangle(d, 150., y, 250., y, 200., y+50.) + call g2_filled_rectangle(d, 300., y, 400., y+50.) + call g2_filled_circle(d, 450., y+25., 25.) + call g2_filled_ellipse(d, 550., y+25., 45., 25.) + call g2_filled_arc(d, 650., y+25., 25., 45., 90., 360.) + + + y=300. + pts(0)=150. + pts(1)=y + pts(2)=175. + pts(3)=y+100. + pts(4)=200. + pts(5)=y + pts(6)=225. + pts(7)=y+100. + pts(8)=250. + pts(9)=y + call g2_poly_line(d, 5., pts) + call g2_pen(d, 19.) + call g2_b_spline(d, 5., pts, 20.) + call g2_pen(d, 1.) + + pts(0)=300. + pts(1)=y + pts(2)=350. + pts(3)=y + pts(4)=375. + pts(5)=y+50. + pts(6)=325. + pts(7)=y+90. + pts(8)=275. + pts(9)=y+50. + call g2_polygon(d, 5., pts) + + pts(0)=450. + pts(1)=y + pts(2)=500. + pts(3)=y + pts(4)=525. + pts(5)=y+50. + pts(6)=475. + pts(7)=y+90. + pts(8)=425. + pts(9)=y+50. + call g2_filled_polygon(d, 5, pts) + + call g2_image(d, 55., 50., 53., 62., penguin) + call g2_image(d, 75., 130., 53., 62., penguin) + call g2_pen(d, 1.) + + call g2_line(d, 225., 448., float(200+19*25), 448.) + do i=1,20 + call g2_pen(d,float(i+1)) + call g2_set_line_width(d, float(i)) + call g2_move(d, float(200+i*25), 450.) + call g2_line_to(d, float(200+i*25), 550.) + enddo + call g2_pen(d,1.) + + call g2_set_line_width(d, 5.) + do i=1,10 + pts(0)=float(1*i) + pts(1)=float(2*i) + pts(2)=float(3*i) + call g2_set_dash(d, 3., pts) + call g2_line(d, 550., float(300+i*8), 750., float(350+i*8)) + enddo + + call g2_set_dash(d, 0., pts) + call g2_set_line_width(d, 5.) + call g2_arc(d, 740., 180., 25., 100., -45.+15., -45.-15.) + call g2_filled_arc(d, 740., 180., 12., 50., -45.+15., -45.-15.) +c---------------------------------------------------------- + call g2_flush(d) + print*,"Done...(Enter)" + read(*,'(a)') str + call g2_close(d) + end +c #eof# diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/handles.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/handles.c new file mode 100755 index 00000000..5bc5d53f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/handles.c @@ -0,0 +1,58 @@ +/***************************************************************************** +** Copyright (C) 1998-2005 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include +#include + +#include + +int main() +{ + int d1, d2; + void *handles[G2_PD_HANDLES_SIZE]; + Display *display; + Drawable *drawable; + GC *gc; + + + d1=g2_open_X11(100, 100); + g2_line(d1, 10, 10, 90, 90); + + g2_get_pd_handles(d1, handles); + display = handles[0]; + drawable = handles[5]; + gc = handles[4]; + + printf("%p %p %p\n", display, drawable, gc); + + XDrawString(display, *drawable, *gc, + 10,10, "OK", 2); + + g2_flush(d1); + + d2=g2_open_PS("handles.ps", g2_A4, g2_PS_port); + g2_get_pd_handles(d2, handles); + printf("%p %p %p\n", handles[0], handles[1], handles[2]); + + + getchar(); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.c new file mode 100755 index 00000000..6b5a1f45 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.c @@ -0,0 +1,63 @@ +static int penguin[53*62] = +{00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00, +00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,01,01,01,01,01,01,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00, +00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,01,01,01,01,01,01,01,01,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00, 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+00,01,01,25,25,25,25,25,25,25,25,25,25,25,25,25,25,25,25,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,25,25,25,25,25,25,25,25,01,01,00,00,00,00,00,00,00, +00,00,01,01,01,01,25,25,25,25,25,25,25,25,25,25,25,25,25,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,01,25,25,25,25,25,25,25,01,01,00,00,00,00,00,00,00,00, +00,00,00,00,00,00,00,00,01,01,01,01,25,25,25,25,25,25,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,25,25,25,25,01,01,01,00,00,00,00,00,00,00,00,00, +00,00,00,00,00,00,00,00,00,00,01,01,01,01,25,25,25,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,01,01,01,01,01,01,00,00,00,00,00,00,00,00,00,00, +00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,00,01,01,01,01,01,00,00,00,00,00,00,00,00,00,00,00,00}; diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.inc b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.inc new file mode 100755 index 00000000..52495e33 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/penguin.inc @@ -0,0 +1,64 @@ + real penguin(1:53,1:62) + data ((penguin(i,j),i=1,53),j=1,62)/ + & 23*0,5*1,25*0, + & 20*0,12*1,21*0, + & 19*0,14*1,20*0, + & 19*0,11*1,1*0,3*1,19*0, + & 18*0,12*1,2*0,2*1,19*0, + & 18*0,17*1,18*0, + & 17*0,19*1,17*0, + & 17*0,19*1,17*0, + & 17*0,19*1,17*0, + & 17*0,3*1,1*0,6*1,3*0,6*1,17*0, + & 17*0,2*1,4*0,3*1,6*0,4*1,17*0, + & 17*0,2*1,1*0,1*1,2*0,2*1,3*0,2*1,2*0,4*1,17*0, + & 17*0,5*1,1*0,2*1,2*0,3*1,2*0,4*1,17*0, + & 17*0,5*1,1*0,3*1,1*0,3*1,2*0,4*1,17*0, + & 17*0,3*1,1*0,7*25,2*1,2*0,4*1,17*0, + & 17*0,4*1,9*25,6*1,17*0, + & 17*0,2*1,13*25,4*1,17*0, + & 18*0,1*1,13*25,4*1,17*0, + & 18*0,2*1,8*25,2*1,2*25,5*1,16*0, + & 18*0,3*1,3*25,2*1,4*25,1*0,3*1,2*0,2*1,15*0, + & 18*0,6*1,4*25,2*1,2*0,2*1,2*0,3*1,14*0, + & 17*0,2*1,2*0,2*1,1*25,4*1,4*0,7*1,14*0, + & 17*0,2*1,2*0,5*1,6*0,7*1,14*0, + & 16*0,3*1,3*0,2*1,9*0,7*1,13*0, + & 15*0,3*1,16*0,7*1,12*0, + & 14*0,3*1,17*0,8*1,11*0, + & 14*0,3*1,17*0,8*1,11*0, + & 14*0,3*1,17*0,3*1,1*0,5*1,10*0, + & 12*0,5*1,18*0,9*1,9*0, + & 12*0,5*1,19*0,3*1,1*0,4*1,9*0, + & 11*0,2*1,1*0,2*1,20*0,9*1,8*0, + & 11*0,5*1,20*0,4*1,1*0,4*1,8*0, + & 11*0,4*1,22*0,8*1,8*0, + & 10*0,4*1,23*0,9*1,7*0, + & 10*0,4*1,24*0,3*1,1*0,5*1,6*0, + & 10*0,4*1,24*0,3*1,1*0,5*1,6*0, + & 9*0,5*1,24*0,3*1,1*0,5*1,6*0, + & 8*0,2*1,1*0,2*1,25*0,3*1,1*0,5*1,6*0, + & 8*0,2*1,1*0,2*1,25*0,3*1,1*0,5*1,6*0, + & 8*0,5*1,25*0,3*1,1*0,5*1,6*0, + & 7*0,6*1,25*0,9*1,6*0, + & 7*0,4*1,1*0,1*1,26*0,8*1,6*0, + & 7*0,5*1,26*0,9*1,6*0, + & 7*0,4*25,2*1,23*0,11*1,6*0, + & 7*0,5*25,2*1,22*0,2*25,8*1,1*25,6*0, + & 6*0,1*1,6*25,3*1,19*0,1*1,3*25,6*1,3*25,5*0, + & 6*0,1*1,7*25,3*1,18*0,1*1,3*25,5*1,3*25,1*1,5*0, + & 5*0,1*1,8*25,3*1,18*0,1*1,4*25,3*1,4*25,1*1,5*0, + & 1*0,13*25,5*1,16*0,1*1,11*25,2*1,4*0, + & 1*1,14*25,5*1,15*0,1*1,11*25,3*1,3*0, + & 1*0,16*25,4*1,14*0,1*1,12*25,3*1,2*0, + & 1*0,1*1,15*25,4*1,14*0,1*1,14*25,2*1,1*0, + & 1*0,1*1,15*25,2*1,14*0,1*1,1*0,1*1,16*25,1*1, + & 1*0,1*1,16*25,1*1,13*0,2*1,1*0,1*1,16*25,1*1, + & 1*0,1*1,17*25,1*1,1*0,1*1,8*0,4*1,1*0,1*1,14*25,2*1,1*0, + & 1*1,18*25,15*1,1*0,1*1,13*25,1*1,3*0, + & 1*1,18*25,17*1,9*25,3*1,5*0, + & 1*0,2*1,16*25,17*1,8*25,2*1,7*0, + & 2*0,4*1,13*25,17*1,7*25,2*1,8*0, + & 8*0,4*1,6*25,3*1,13*0,3*1,4*25,3*1,9*0, + & 10*0,4*1,3*25,2*1,15*0,9*1,10*0, + & 14*0,3*1,19*0,5*1,12*0/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/pointer.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/pointer.c new file mode 100755 index 00000000..48968a87 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/pointer.c @@ -0,0 +1,46 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + +int main() +{ + int d; + double x, y; + unsigned int button; + + d=g2_open_X11(100, 50); + + g2_set_coordinate_system(d, 50, 25, 50., 25.); + + g2_line(d, -1, 0, 1, 0); + g2_line(d, 0, -1, 0, 1); + + printf("Press to start\n"); + getchar(); + + for(;;) { + g2_query_pointer(d, &x, &y, &button); + printf("%f %f 0x%04x\n", x, y, button); + } + + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_FIG.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_FIG.c new file mode 100755 index 00000000..74da920f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_FIG.c @@ -0,0 +1,30 @@ +/***************************************************************************** +** Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include + +int main() +{ + int d; + d=g2_open_FIG("simple.fig"); + g2_line(d, 10, 10, 90, 90); + g2_close(d); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_PS.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_PS.c new file mode 100755 index 00000000..29af9014 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_PS.c @@ -0,0 +1,30 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include + +int main() +{ + int d; + d=g2_open_PS("simple.ps", g2_A4, g2_PS_port); + g2_line(d, 10, 10, 90, 90); + g2_close(d); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_X11.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_X11.c new file mode 100755 index 00000000..c2686092 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_X11.c @@ -0,0 +1,31 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + +int main() +{ + int d; + d=g2_open_X11(100, 100); + g2_line(d, 10, 10, 90, 90); + getchar(); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_gd.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_gd.c new file mode 100755 index 00000000..4871aee6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_gd.c @@ -0,0 +1,31 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include + +int main() +{ + int d; + + d=g2_open_gd("simple.png", 100, 100, g2_gd_png); + g2_line(d, 10, 10, 90, 90); + g2_close(d); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_win32.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_win32.c new file mode 100755 index 00000000..8dee671c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/simple_win32.c @@ -0,0 +1,31 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + +int main() +{ + int d; + d=g2_open_win32(100, 100, "simple_win32", 0); + g2_line(d, 10, 10, 90, 90); + getchar(); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/xlink.opt b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/xlink.opt new file mode 100755 index 00000000..6bc5bd48 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/demo/xlink.opt @@ -0,0 +1 @@ +sys$share:decw$xlibshr/share diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/descrip.mms b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/descrip.mms new file mode 100755 index 00000000..e5cc3601 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/descrip.mms @@ -0,0 +1,71 @@ +! +! VMS descrip.mms for g2 +! +GD_INCLUDE = [.-.-.GD-1_8_4] + + +.IFDEF debug +CC_FLAGS = /noopt/debug/nolist/warnings/include_directory=("./src",$(GD_INCLUDE)) \ + /define=(DO_PS, DO_X11, DO_GD) +.ELSE +CC_FLAGS = /nolist/warnings/include_directory=("./src",$(GD_INCLUDE)) \ + /define=(DO_PS, DO_X11, DO_GD) +.ENDIF + +! +! Object files +! +OBJ = [.src]g2_device.obj, [.src]g2_fif.obj, [.src]g2_graphic_pd.obj, \ + [.src]g2_physical_device.obj, [.src]g2_ui_control.obj, \ + [.src]g2_ui_device.obj, [.src]g2_ui_graphic.obj, \ + [.src]g2_ui_virtual_device.obj, [.src]g2_util.obj, \ + [.src]g2_virtual_device.obj, [.src]g2_control_pd.obj, \ + [.src]g2_splines.obj +OBJ_X11 = [.src.X11]g2_X11.obj +OBJ_PS = [.src.PS]g2_PS.obj +OBJ_GD = [.src.GD]g2_GD.obj + +HEADERS = [.src]g2.h, [.src]g2_config.h, [.src]g2_device.h, \ + [.src]g2_funix.h, [.src]g2_graphic_pd.h, \ + [.src]g2_physical_device.h, [.src]g2_util.h, \ + [.src]g2_virtual_device.h, [.src]g2_control_pd.h +HEADERS_X11 = [.src.X11]g2_X11.h, [.src.X11]g2_X11_P.h, \ + [.src.X11]g2_X11_funix.h +HEADERS_PS = [.src.PS]g2_PS.h, [.src.PS]g2_PS_P.h, \ + [.src.PS]g2_PS_definitions.h, [.src.PS]g2_PS_funix.h +HEADERS_GD = [.src.GD]g2_GD.h, [.src.GD]g2_GD_P.h, [.src.GD]g2_GD_funix.h +! +! Rules +! +.c.obj : ; cc $(CC_FLAGS)/obj=$(mms$target) $(mms$source) + + +all : g2.olb + @ write sys$output "Done." + +g2.olb : $(OBJ) $(OBJ_X11) $(OBJ_PS) $(OBJ_GD) + library/create g2.olb $(OBJ), $(OBJ_X11), $(OBJ_PS), $(OBJ_GD) + +clean : + delete [...]*.exe;* , [...]*.obj;* , [...]*.olb;* + + +! +! Dependencies +! +[.src]g2_device.obj : [.src]g2_device.c $(HEADERS) +[.src]g2_fif.obj : [.src]g2_fif.c $(HEADERS) +[.src]g2_graphic_pd.obj : [.src]g2_graphic_pd.c $(HEADERS) +[.src]g2_physical_device.obj : [.src]g2_physical_device.c $(HEADERS) +[.src]g2_ui_control.obj : [.src]g2_ui_control.c $(HEADERS) +[.src]g2_ui_device.obj : [.src]g2_ui_device.c $(HEADERS) +[.src]g2_ui_graphic.obj : [.src]g2_ui_graphic.c $(HEADERS) +[.src]g2_ui_virtual_device.obj : [.src]g2_ui_virtual_device.c $(HEADERS) +[.src]g2_util.obj : [.src]g2_util.c $(HEADERS) +[.src]g2_virtual_device.obj : [.src]g2_virtual_device.c $(HEADERS) +[.src]g2_splines.obj : [.src]g2_splines.c $(HEADERS) + +[.X11]g2_X11.obj : [.src.X11]g2_X11.c $(HEADERS) $(HEADERS_X11) +[.PS]g2_PS.obj : [.src.PS]g2_PS.c $(HEADERS) $(HEADERS_PS) +[.GD]g2_GD.obj : [.src.GD]g2_GD.c $(HEADERS) $(HEADERS_GD) + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Repository new file mode 100755 index 00000000..e05ed891 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/doc/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Entries new file mode 100755 index 00000000..36fcdcd8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Entries @@ -0,0 +1,3 @@ +D/CVS//// +/Doxyfile/1.1/Tue Jun 14 21:14:27 2005// +/g2_main.dox/1.1/Mon Apr 5 21:40:53 2004// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Repository new file mode 100755 index 00000000..908db64f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/doc diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/Doxyfile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/Doxyfile new file mode 100755 index 00000000..a9d6e6a9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/Doxyfile @@ -0,0 +1,1117 @@ +# Doxyfile 1.3.6 + +# This file describes the settings to be used by the documentation system +# doxygen (www.doxygen.org) for a project +# +# All text after a hash (#) is considered a comment and will be ignored +# The format is: +# TAG = value [value, ...] +# For lists items can also be appended using: +# TAG += value [value, ...] +# Values that contain spaces should be placed between quotes (" ") + +#--------------------------------------------------------------------------- +# Project related configuration options +#--------------------------------------------------------------------------- + +# The PROJECT_NAME tag is a single word (or a sequence of words surrounded +# by quotes) that should identify the project. + +PROJECT_NAME = g2 + +# The PROJECT_NUMBER tag can be used to enter a project or revision number. +# This could be handy for archiving the generated documentation or +# if some version control system is used. + +PROJECT_NUMBER = 0.7x + +# The OUTPUT_DIRECTORY tag is used to specify the (relative or absolute) +# base path where the generated documentation will be put. +# If a relative path is entered, it will be relative to the location +# where doxygen was started. If left blank the current directory will be used. + +OUTPUT_DIRECTORY = + +# The OUTPUT_LANGUAGE tag is used to specify the language in which all +# documentation generated by doxygen is written. Doxygen will use this +# information to generate all constant output in the proper language. +# The default language is English, other supported languages are: +# Brazilian, Catalan, Chinese, Chinese-Traditional, Croatian, Czech, Danish, Dutch, +# Finnish, French, German, Greek, Hungarian, Italian, Japanese, Japanese-en +# (Japanese with English messages), Korean, Korean-en, Norwegian, Polish, Portuguese, +# Romanian, Russian, Serbian, Slovak, Slovene, Spanish, Swedish, and Ukrainian. + +OUTPUT_LANGUAGE = English + +# This tag can be used to specify the encoding used in the generated output. +# The encoding is not always determined by the language that is chosen, +# but also whether or not the output is meant for Windows or non-Windows users. +# In case there is a difference, setting the USE_WINDOWS_ENCODING tag to YES +# forces the Windows encoding (this is the default for the Windows binary), +# whereas setting the tag to NO uses a Unix-style encoding (the default for +# all platforms other than Windows). + +USE_WINDOWS_ENCODING = NO + +# If the BRIEF_MEMBER_DESC tag is set to YES (the default) Doxygen will +# include brief member descriptions after the members that are listed in +# the file and class documentation (similar to JavaDoc). +# Set to NO to disable this. + +BRIEF_MEMBER_DESC = YES + +# If the REPEAT_BRIEF tag is set to YES (the default) Doxygen will prepend +# the brief description of a member or function before the detailed description. +# Note: if both HIDE_UNDOC_MEMBERS and BRIEF_MEMBER_DESC are set to NO, the +# brief descriptions will be completely suppressed. + +REPEAT_BRIEF = YES + +# This tag implements a quasi-intelligent brief description abbreviator +# that is used to form the text in various listings. Each string +# in this list, if found as the leading text of the brief description, will be +# stripped from the text and the result after processing the whole list, is used +# as the annotated text. Otherwise, the brief description is used as-is. If left +# blank, the following values are used ("$name" is automatically replaced with the +# name of the entity): "The $name class" "The $name widget" "The $name file" +# "is" "provides" "specifies" "contains" "represents" "a" "an" "the" + +ABBREVIATE_BRIEF = + +# If the ALWAYS_DETAILED_SEC and REPEAT_BRIEF tags are both set to YES then +# Doxygen will generate a detailed section even if there is only a brief +# description. + +ALWAYS_DETAILED_SEC = NO + +# If the INLINE_INHERITED_MEMB tag is set to YES, doxygen will show all inherited +# members of a class in the documentation of that class as if those members were +# ordinary class members. Constructors, destructors and assignment operators of +# the base classes will not be shown. + +INLINE_INHERITED_MEMB = NO + +# If the FULL_PATH_NAMES tag is set to YES then Doxygen will prepend the full +# path before files name in the file list and in the header files. If set +# to NO the shortest path that makes the file name unique will be used. + +FULL_PATH_NAMES = NO + +# If the FULL_PATH_NAMES tag is set to YES then the STRIP_FROM_PATH tag +# can be used to strip a user-defined part of the path. Stripping is +# only done if one of the specified strings matches the left-hand part of +# the path. It is allowed to use relative paths in the argument list. +# If left blank the directory from which doxygen is run is used as the +# path to strip. + +STRIP_FROM_PATH = + +# If the SHORT_NAMES tag is set to YES, doxygen will generate much shorter +# (but less readable) file names. This can be useful is your file systems +# doesn't support long names like on DOS, Mac, or CD-ROM. + +SHORT_NAMES = NO + +# If the JAVADOC_AUTOBRIEF tag is set to YES then Doxygen +# will interpret the first line (until the first dot) of a JavaDoc-style +# comment as the brief description. If set to NO, the JavaDoc +# comments will behave just like the Qt-style comments (thus requiring an +# explicit @brief command for a brief description. + +JAVADOC_AUTOBRIEF = NO + +# The MULTILINE_CPP_IS_BRIEF tag can be set to YES to make Doxygen +# treat a multi-line C++ special comment block (i.e. a block of //! or /// +# comments) as a brief description. This used to be the default behaviour. +# The new default is to treat a multi-line C++ comment block as a detailed +# description. Set this tag to YES if you prefer the old behaviour instead. + +MULTILINE_CPP_IS_BRIEF = NO + +# If the DETAILS_AT_TOP tag is set to YES then Doxygen +# will output the detailed description near the top, like JavaDoc. +# If set to NO, the detailed description appears after the member +# documentation. + +DETAILS_AT_TOP = NO + +# If the INHERIT_DOCS tag is set to YES (the default) then an undocumented +# member inherits the documentation from any documented member that it +# re-implements. + +INHERIT_DOCS = YES + +# If member grouping is used in the documentation and the DISTRIBUTE_GROUP_DOC +# tag is set to YES, then doxygen will reuse the documentation of the first +# member in the group (if any) for the other members of the group. By default +# all members of a group must be documented explicitly. + +DISTRIBUTE_GROUP_DOC = NO + +# The TAB_SIZE tag can be used to set the number of spaces in a tab. +# Doxygen uses this value to replace tabs by spaces in code fragments. + +TAB_SIZE = 8 + +# This tag can be used to specify a number of aliases that acts +# as commands in the documentation. An alias has the form "name=value". +# For example adding "sideeffect=\par Side Effects:\n" will allow you to +# put the command \sideeffect (or @sideeffect) in the documentation, which +# will result in a user-defined paragraph with heading "Side Effects:". +# You can put \n's in the value part of an alias to insert newlines. + +ALIASES = + +# Set the OPTIMIZE_OUTPUT_FOR_C tag to YES if your project consists of C sources +# only. Doxygen will then generate output that is more tailored for C. +# For instance, some of the names that are used will be different. The list +# of all members will be omitted, etc. + +OPTIMIZE_OUTPUT_FOR_C = YES + +# Set the OPTIMIZE_OUTPUT_JAVA tag to YES if your project consists of Java sources +# only. Doxygen will then generate output that is more tailored for Java. +# For instance, namespaces will be presented as packages, qualified scopes +# will look different, etc. + +OPTIMIZE_OUTPUT_JAVA = NO + +# Set the SUBGROUPING tag to YES (the default) to allow class member groups of +# the same type (for instance a group of public functions) to be put as a +# subgroup of that type (e.g. under the Public Functions section). Set it to +# NO to prevent subgrouping. Alternatively, this can be done per class using +# the \nosubgrouping command. + +SUBGROUPING = YES + +#--------------------------------------------------------------------------- +# Build related configuration options +#--------------------------------------------------------------------------- + +# If the EXTRACT_ALL tag is set to YES doxygen will assume all entities in +# documentation are documented, even if no documentation was available. +# Private class members and static file members will be hidden unless +# the EXTRACT_PRIVATE and EXTRACT_STATIC tags are set to YES + +EXTRACT_ALL = NO + +# If the EXTRACT_PRIVATE tag is set to YES all private members of a class +# will be included in the documentation. + +EXTRACT_PRIVATE = YES + +# If the EXTRACT_STATIC tag is set to YES all static members of a file +# will be included in the documentation. + +EXTRACT_STATIC = YES + +# If the EXTRACT_LOCAL_CLASSES tag is set to YES classes (and structs) +# defined locally in source files will be included in the documentation. +# If set to NO only classes defined in header files are included. + +EXTRACT_LOCAL_CLASSES = YES + +# If the HIDE_UNDOC_MEMBERS tag is set to YES, Doxygen will hide all +# undocumented members of documented classes, files or namespaces. +# If set to NO (the default) these members will be included in the +# various overviews, but no documentation section is generated. +# This option has no effect if EXTRACT_ALL is enabled. + +HIDE_UNDOC_MEMBERS = NO + +# If the HIDE_UNDOC_CLASSES tag is set to YES, Doxygen will hide all +# undocumented classes that are normally visible in the class hierarchy. +# If set to NO (the default) these classes will be included in the various +# overviews. This option has no effect if EXTRACT_ALL is enabled. + +HIDE_UNDOC_CLASSES = NO + +# If the HIDE_FRIEND_COMPOUNDS tag is set to YES, Doxygen will hide all +# friend (class|struct|union) declarations. +# If set to NO (the default) these declarations will be included in the +# documentation. + +HIDE_FRIEND_COMPOUNDS = NO + +# If the HIDE_IN_BODY_DOCS tag is set to YES, Doxygen will hide any +# documentation blocks found inside the body of a function. +# If set to NO (the default) these blocks will be appended to the +# function's detailed documentation block. + +HIDE_IN_BODY_DOCS = NO + +# The INTERNAL_DOCS tag determines if documentation +# that is typed after a \internal command is included. If the tag is set +# to NO (the default) then the documentation will be excluded. +# Set it to YES to include the internal documentation. + +INTERNAL_DOCS = NO + +# If the CASE_SENSE_NAMES tag is set to NO then Doxygen will only generate +# file names in lower-case letters. If set to YES upper-case letters are also +# allowed. This is useful if you have classes or files whose names only differ +# in case and if your file system supports case sensitive file names. Windows +# users are advised to set this option to NO. + +CASE_SENSE_NAMES = YES + +# If the HIDE_SCOPE_NAMES tag is set to NO (the default) then Doxygen +# will show members with their full class and namespace scopes in the +# documentation. If set to YES the scope will be hidden. + +HIDE_SCOPE_NAMES = NO + +# If the SHOW_INCLUDE_FILES tag is set to YES (the default) then Doxygen +# will put a list of the files that are included by a file in the documentation +# of that file. + +SHOW_INCLUDE_FILES = YES + +# If the INLINE_INFO tag is set to YES (the default) then a tag [inline] +# is inserted in the documentation for inline members. + +INLINE_INFO = YES + +# If the SORT_MEMBER_DOCS tag is set to YES (the default) then doxygen +# will sort the (detailed) documentation of file and class members +# alphabetically by member name. If set to NO the members will appear in +# declaration order. + +SORT_MEMBER_DOCS = YES + +# If the SORT_BRIEF_DOCS tag is set to YES then doxygen will sort the +# brief documentation of file, namespace and class members alphabetically +# by member name. If set to NO (the default) the members will appear in +# declaration order. + +SORT_BRIEF_DOCS = NO + +# If the SORT_BY_SCOPE_NAME tag is set to YES, the class list will be +# sorted by fully-qualified names, including namespaces. If set to +# NO (the default), the class list will be sorted only by class name, +# not including the namespace part. +# Note: This option is not very useful if HIDE_SCOPE_NAMES is set to YES. +# Note: This option applies only to the class list, not to the +# alphabetical list. + +SORT_BY_SCOPE_NAME = NO + +# The GENERATE_TODOLIST tag can be used to enable (YES) or +# disable (NO) the todo list. This list is created by putting \todo +# commands in the documentation. + +GENERATE_TODOLIST = YES + +# The GENERATE_TESTLIST tag can be used to enable (YES) or +# disable (NO) the test list. This list is created by putting \test +# commands in the documentation. + +GENERATE_TESTLIST = YES + +# The GENERATE_BUGLIST tag can be used to enable (YES) or +# disable (NO) the bug list. This list is created by putting \bug +# commands in the documentation. + +GENERATE_BUGLIST = YES + +# The GENERATE_DEPRECATEDLIST tag can be used to enable (YES) or +# disable (NO) the deprecated list. This list is created by putting +# \deprecated commands in the documentation. + +GENERATE_DEPRECATEDLIST= YES + +# The ENABLED_SECTIONS tag can be used to enable conditional +# documentation sections, marked by \if sectionname ... \endif. + +ENABLED_SECTIONS = + +# The MAX_INITIALIZER_LINES tag determines the maximum number of lines +# the initial value of a variable or define consists of for it to appear in +# the documentation. If the initializer consists of more lines than specified +# here it will be hidden. Use a value of 0 to hide initializers completely. +# The appearance of the initializer of individual variables and defines in the +# documentation can be controlled using \showinitializer or \hideinitializer +# command in the documentation regardless of this setting. + +MAX_INITIALIZER_LINES = 30 + +# Set the SHOW_USED_FILES tag to NO to disable the list of files generated +# at the bottom of the documentation of classes and structs. If set to YES the +# list will mention the files that were used to generate the documentation. + +SHOW_USED_FILES = YES + +#--------------------------------------------------------------------------- +# configuration options related to warning and progress messages +#--------------------------------------------------------------------------- + +# The QUIET tag can be used to turn on/off the messages that are generated +# by doxygen. Possible values are YES and NO. If left blank NO is used. + +QUIET = YES + +# The WARNINGS tag can be used to turn on/off the warning messages that are +# generated by doxygen. Possible values are YES and NO. If left blank +# NO is used. + +WARNINGS = YES + +# If WARN_IF_UNDOCUMENTED is set to YES, then doxygen will generate warnings +# for undocumented members. If EXTRACT_ALL is set to YES then this flag will +# automatically be disabled. + +WARN_IF_UNDOCUMENTED = YES + +# If WARN_IF_DOC_ERROR is set to YES, doxygen will generate warnings for +# potential errors in the documentation, such as not documenting some +# parameters in a documented function, or documenting parameters that +# don't exist or using markup commands wrongly. + +WARN_IF_DOC_ERROR = YES + +# The WARN_FORMAT tag determines the format of the warning messages that +# doxygen can produce. The string should contain the $file, $line, and $text +# tags, which will be replaced by the file and line number from which the +# warning originated and the warning text. + +WARN_FORMAT = "$file:$line: $text" + +# The WARN_LOGFILE tag can be used to specify a file to which warning +# and error messages should be written. If left blank the output is written +# to stderr. + +WARN_LOGFILE = + +#--------------------------------------------------------------------------- +# configuration options related to the input files +#--------------------------------------------------------------------------- + +# The INPUT tag can be used to specify the files and/or directories that contain +# documented source files. You may enter file names like "myfile.cpp" or +# directories like "/usr/src/myproject". Separate the files or directories +# with spaces. + +INPUT = ../src/ . + +# If the value of the INPUT tag contains directories, you can use the +# FILE_PATTERNS tag to specify one or more wildcard pattern (like *.cpp +# and *.h) to filter out the source-files in the directories. If left +# blank the following patterns are tested: +# *.c *.cc *.cxx *.cpp *.c++ *.java *.ii *.ixx *.ipp *.i++ *.inl *.h *.hh *.hxx *.hpp +# *.h++ *.idl *.odl *.cs *.php *.php3 *.inc + +FILE_PATTERNS = *.c *.h *.dox + +# The RECURSIVE tag can be used to turn specify whether or not subdirectories +# should be searched for input files as well. Possible values are YES and NO. +# If left blank NO is used. + +RECURSIVE = YES + +# The EXCLUDE tag can be used to specify files and/or directories that should +# excluded from the INPUT source files. This way you can easily exclude a +# subdirectory from a directory tree whose root is specified with the INPUT tag. + +EXCLUDE = ../src/g2_fif.c g2_fif.h + +# The EXCLUDE_SYMLINKS tag can be used select whether or not files or directories +# that are symbolic links (a Unix filesystem feature) are excluded from the input. + +EXCLUDE_SYMLINKS = NO + +# If the value of the INPUT tag contains directories, you can use the +# EXCLUDE_PATTERNS tag to specify one or more wildcard patterns to exclude +# certain files from those directories. + +EXCLUDE_PATTERNS = + +# The EXAMPLE_PATH tag can be used to specify one or more files or +# directories that contain example code fragments that are included (see +# the \include command). + +EXAMPLE_PATH = + +# If the value of the EXAMPLE_PATH tag contains directories, you can use the +# EXAMPLE_PATTERNS tag to specify one or more wildcard pattern (like *.cpp +# and *.h) to filter out the source-files in the directories. If left +# blank all files are included. + +EXAMPLE_PATTERNS = + +# If the EXAMPLE_RECURSIVE tag is set to YES then subdirectories will be +# searched for input files to be used with the \include or \dontinclude +# commands irrespective of the value of the RECURSIVE tag. +# Possible values are YES and NO. If left blank NO is used. + +EXAMPLE_RECURSIVE = NO + +# The IMAGE_PATH tag can be used to specify one or more files or +# directories that contain image that are included in the documentation (see +# the \image command). + +IMAGE_PATH = + +# The INPUT_FILTER tag can be used to specify a program that doxygen should +# invoke to filter for each input file. Doxygen will invoke the filter program +# by executing (via popen()) the command , where +# is the value of the INPUT_FILTER tag, and is the name of an +# input file. Doxygen will then use the output that the filter program writes +# to standard output. + +INPUT_FILTER = + +# If the FILTER_SOURCE_FILES tag is set to YES, the input filter (if set using +# INPUT_FILTER) will be used to filter the input files when producing source +# files to browse (i.e. when SOURCE_BROWSER is set to YES). + +FILTER_SOURCE_FILES = NO + +#--------------------------------------------------------------------------- +# configuration options related to source browsing +#--------------------------------------------------------------------------- + +# If the SOURCE_BROWSER tag is set to YES then a list of source files will +# be generated. Documented entities will be cross-referenced with these sources. +# Note: To get rid of all source code in the generated output, make sure also +# VERBATIM_HEADERS is set to NO. + +SOURCE_BROWSER = NO + +# Setting the INLINE_SOURCES tag to YES will include the body +# of functions and classes directly in the documentation. + +INLINE_SOURCES = NO + +# Setting the STRIP_CODE_COMMENTS tag to YES (the default) will instruct +# doxygen to hide any special comment blocks from generated source code +# fragments. Normal C and C++ comments will always remain visible. + +STRIP_CODE_COMMENTS = YES + +# If the REFERENCED_BY_RELATION tag is set to YES (the default) +# then for each documented function all documented +# functions referencing it will be listed. + +REFERENCED_BY_RELATION = YES + +# If the REFERENCES_RELATION tag is set to YES (the default) +# then for each documented function all documented entities +# called/used by that function will be listed. + +REFERENCES_RELATION = YES + +# If the VERBATIM_HEADERS tag is set to YES (the default) then Doxygen +# will generate a verbatim copy of the header file for each class for +# which an include is specified. Set to NO to disable this. + +VERBATIM_HEADERS = YES + +#--------------------------------------------------------------------------- +# configuration options related to the alphabetical class index +#--------------------------------------------------------------------------- + +# If the ALPHABETICAL_INDEX tag is set to YES, an alphabetical index +# of all compounds will be generated. Enable this if the project +# contains a lot of classes, structs, unions or interfaces. + +ALPHABETICAL_INDEX = NO + +# If the alphabetical index is enabled (see ALPHABETICAL_INDEX) then +# the COLS_IN_ALPHA_INDEX tag can be used to specify the number of columns +# in which this list will be split (can be a number in the range [1..20]) + +COLS_IN_ALPHA_INDEX = 5 + +# In case all classes in a project start with a common prefix, all +# classes will be put under the same header in the alphabetical index. +# The IGNORE_PREFIX tag can be used to specify one or more prefixes that +# should be ignored while generating the index headers. + +IGNORE_PREFIX = + +#--------------------------------------------------------------------------- +# configuration options related to the HTML output +#--------------------------------------------------------------------------- + +# If the GENERATE_HTML tag is set to YES (the default) Doxygen will +# generate HTML output. + +GENERATE_HTML = YES + +# The HTML_OUTPUT tag is used to specify where the HTML docs will be put. +# If a relative path is entered the value of OUTPUT_DIRECTORY will be +# put in front of it. If left blank `html' will be used as the default path. + +HTML_OUTPUT = html + +# The HTML_FILE_EXTENSION tag can be used to specify the file extension for +# each generated HTML page (for example: .htm,.php,.asp). If it is left blank +# doxygen will generate files with .html extension. + +HTML_FILE_EXTENSION = .html + +# The HTML_HEADER tag can be used to specify a personal HTML header for +# each generated HTML page. If it is left blank doxygen will generate a +# standard header. + +HTML_HEADER = + +# The HTML_FOOTER tag can be used to specify a personal HTML footer for +# each generated HTML page. If it is left blank doxygen will generate a +# standard footer. + +HTML_FOOTER = + +# The HTML_STYLESHEET tag can be used to specify a user-defined cascading +# style sheet that is used by each HTML page. It can be used to +# fine-tune the look of the HTML output. If the tag is left blank doxygen +# will generate a default style sheet. Note that doxygen will try to copy +# the style sheet file to the HTML output directory, so don't put your own +# stylesheet in the HTML output directory as well, or it will be erased! + +HTML_STYLESHEET = + +# If the HTML_ALIGN_MEMBERS tag is set to YES, the members of classes, +# files or namespaces will be aligned in HTML using tables. If set to +# NO a bullet list will be used. + +HTML_ALIGN_MEMBERS = YES + +# If the GENERATE_HTMLHELP tag is set to YES, additional index files +# will be generated that can be used as input for tools like the +# Microsoft HTML help workshop to generate a compressed HTML help file (.chm) +# of the generated HTML documentation. + +GENERATE_HTMLHELP = NO + +# If the GENERATE_HTMLHELP tag is set to YES, the CHM_FILE tag can +# be used to specify the file name of the resulting .chm file. You +# can add a path in front of the file if the result should not be +# written to the html output directory. + +CHM_FILE = + +# If the GENERATE_HTMLHELP tag is set to YES, the HHC_LOCATION tag can +# be used to specify the location (absolute path including file name) of +# the HTML help compiler (hhc.exe). If non-empty doxygen will try to run +# the HTML help compiler on the generated index.hhp. + +HHC_LOCATION = + +# If the GENERATE_HTMLHELP tag is set to YES, the GENERATE_CHI flag +# controls if a separate .chi index file is generated (YES) or that +# it should be included in the master .chm file (NO). + +GENERATE_CHI = NO + +# If the GENERATE_HTMLHELP tag is set to YES, the BINARY_TOC flag +# controls whether a binary table of contents is generated (YES) or a +# normal table of contents (NO) in the .chm file. + +BINARY_TOC = NO + +# The TOC_EXPAND flag can be set to YES to add extra items for group members +# to the contents of the HTML help documentation and to the tree view. + +TOC_EXPAND = NO + +# The DISABLE_INDEX tag can be used to turn on/off the condensed index at +# top of each HTML page. The value NO (the default) enables the index and +# the value YES disables it. + +DISABLE_INDEX = NO + +# This tag can be used to set the number of enum values (range [1..20]) +# that doxygen will group on one line in the generated HTML documentation. + +ENUM_VALUES_PER_LINE = 4 + +# If the GENERATE_TREEVIEW tag is set to YES, a side panel will be +# generated containing a tree-like index structure (just like the one that +# is generated for HTML Help). For this to work a browser that supports +# JavaScript, DHTML, CSS and frames is required (for instance Mozilla 1.0+, +# Netscape 6.0+, Internet explorer 5.0+, or Konqueror). Windows users are +# probably better off using the HTML help feature. + +GENERATE_TREEVIEW = NO + +# If the treeview is enabled (see GENERATE_TREEVIEW) then this tag can be +# used to set the initial width (in pixels) of the frame in which the tree +# is shown. + +TREEVIEW_WIDTH = 250 + +#--------------------------------------------------------------------------- +# configuration options related to the LaTeX output +#--------------------------------------------------------------------------- + +# If the GENERATE_LATEX tag is set to YES (the default) Doxygen will +# generate Latex output. + +GENERATE_LATEX = YES + +# The LATEX_OUTPUT tag is used to specify where the LaTeX docs will be put. +# If a relative path is entered the value of OUTPUT_DIRECTORY will be +# put in front of it. If left blank `latex' will be used as the default path. + +LATEX_OUTPUT = latex + +# The LATEX_CMD_NAME tag can be used to specify the LaTeX command name to be +# invoked. If left blank `latex' will be used as the default command name. + +LATEX_CMD_NAME = latex + +# The MAKEINDEX_CMD_NAME tag can be used to specify the command name to +# generate index for LaTeX. If left blank `makeindex' will be used as the +# default command name. + +MAKEINDEX_CMD_NAME = makeindex + +# If the COMPACT_LATEX tag is set to YES Doxygen generates more compact +# LaTeX documents. This may be useful for small projects and may help to +# save some trees in general. + +COMPACT_LATEX = NO + +# The PAPER_TYPE tag can be used to set the paper type that is used +# by the printer. Possible values are: a4, a4wide, letter, legal and +# executive. If left blank a4wide will be used. + +PAPER_TYPE = + +# The EXTRA_PACKAGES tag can be to specify one or more names of LaTeX +# packages that should be included in the LaTeX output. + +EXTRA_PACKAGES = + +# The LATEX_HEADER tag can be used to specify a personal LaTeX header for +# the generated latex document. The header should contain everything until +# the first chapter. If it is left blank doxygen will generate a +# standard header. Notice: only use this tag if you know what you are doing! + +LATEX_HEADER = + +# If the PDF_HYPERLINKS tag is set to YES, the LaTeX that is generated +# is prepared for conversion to pdf (using ps2pdf). The pdf file will +# contain links (just like the HTML output) instead of page references +# This makes the output suitable for online browsing using a pdf viewer. + +PDF_HYPERLINKS = NO + +# If the USE_PDFLATEX tag is set to YES, pdflatex will be used instead of +# plain latex in the generated Makefile. Set this option to YES to get a +# higher quality PDF documentation. + +USE_PDFLATEX = NO + +# If the LATEX_BATCHMODE tag is set to YES, doxygen will add the \\batchmode. +# command to the generated LaTeX files. This will instruct LaTeX to keep +# running if errors occur, instead of asking the user for help. +# This option is also used when generating formulas in HTML. + +LATEX_BATCHMODE = NO + +# If LATEX_HIDE_INDICES is set to YES then doxygen will not +# include the index chapters (such as File Index, Compound Index, etc.) +# in the output. + +LATEX_HIDE_INDICES = NO + +#--------------------------------------------------------------------------- +# configuration options related to the RTF output +#--------------------------------------------------------------------------- + +# If the GENERATE_RTF tag is set to YES Doxygen will generate RTF output +# The RTF output is optimized for Word 97 and may not look very pretty with +# other RTF readers or editors. + +GENERATE_RTF = NO + +# The RTF_OUTPUT tag is used to specify where the RTF docs will be put. +# If a relative path is entered the value of OUTPUT_DIRECTORY will be +# put in front of it. If left blank `rtf' will be used as the default path. + +RTF_OUTPUT = rtf + +# If the COMPACT_RTF tag is set to YES Doxygen generates more compact +# RTF documents. This may be useful for small projects and may help to +# save some trees in general. + +COMPACT_RTF = NO + +# If the RTF_HYPERLINKS tag is set to YES, the RTF that is generated +# will contain hyperlink fields. The RTF file will +# contain links (just like the HTML output) instead of page references. +# This makes the output suitable for online browsing using WORD or other +# programs which support those fields. +# Note: wordpad (write) and others do not support links. + +RTF_HYPERLINKS = NO + +# Load stylesheet definitions from file. Syntax is similar to doxygen's +# config file, i.e. a series of assignments. You only have to provide +# replacements, missing definitions are set to their default value. + +RTF_STYLESHEET_FILE = + +# Set optional variables used in the generation of an rtf document. +# Syntax is similar to doxygen's config file. + +RTF_EXTENSIONS_FILE = + +#--------------------------------------------------------------------------- +# configuration options related to the man page output +#--------------------------------------------------------------------------- + +# If the GENERATE_MAN tag is set to YES (the default) Doxygen will +# generate man pages + +GENERATE_MAN = NO + +# The MAN_OUTPUT tag is used to specify where the man pages will be put. +# If a relative path is entered the value of OUTPUT_DIRECTORY will be +# put in front of it. If left blank `man' will be used as the default path. + +MAN_OUTPUT = man + +# The MAN_EXTENSION tag determines the extension that is added to +# the generated man pages (default is the subroutine's section .3) + +MAN_EXTENSION = .3 + +# If the MAN_LINKS tag is set to YES and Doxygen generates man output, +# then it will generate one additional man file for each entity +# documented in the real man page(s). These additional files +# only source the real man page, but without them the man command +# would be unable to find the correct page. The default is NO. + +MAN_LINKS = NO + +#--------------------------------------------------------------------------- +# configuration options related to the XML output +#--------------------------------------------------------------------------- + +# If the GENERATE_XML tag is set to YES Doxygen will +# generate an XML file that captures the structure of +# the code including all documentation. + +GENERATE_XML = NO + +# The XML_OUTPUT tag is used to specify where the XML pages will be put. +# If a relative path is entered the value of OUTPUT_DIRECTORY will be +# put in front of it. If left blank `xml' will be used as the default path. + +XML_OUTPUT = xml + +# The XML_SCHEMA tag can be used to specify an XML schema, +# which can be used by a validating XML parser to check the +# syntax of the XML files. + +XML_SCHEMA = + +# The XML_DTD tag can be used to specify an XML DTD, +# which can be used by a validating XML parser to check the +# syntax of the XML files. + +XML_DTD = + +# If the XML_PROGRAMLISTING tag is set to YES Doxygen will +# dump the program listings (including syntax highlighting +# and cross-referencing information) to the XML output. Note that +# enabling this will significantly increase the size of the XML output. + +XML_PROGRAMLISTING = YES + +#--------------------------------------------------------------------------- +# configuration options for the AutoGen Definitions output +#--------------------------------------------------------------------------- + +# If the GENERATE_AUTOGEN_DEF tag is set to YES Doxygen will +# generate an AutoGen Definitions (see autogen.sf.net) file +# that captures the structure of the code including all +# documentation. Note that this feature is still experimental +# and incomplete at the moment. + +GENERATE_AUTOGEN_DEF = NO + +#--------------------------------------------------------------------------- +# configuration options related to the Perl module output +#--------------------------------------------------------------------------- + +# If the GENERATE_PERLMOD tag is set to YES Doxygen will +# generate a Perl module file that captures the structure of +# the code including all documentation. Note that this +# feature is still experimental and incomplete at the +# moment. + +GENERATE_PERLMOD = NO + +# If the PERLMOD_LATEX tag is set to YES Doxygen will generate +# the necessary Makefile rules, Perl scripts and LaTeX code to be able +# to generate PDF and DVI output from the Perl module output. + +PERLMOD_LATEX = NO + +# If the PERLMOD_PRETTY tag is set to YES the Perl module output will be +# nicely formatted so it can be parsed by a human reader. This is useful +# if you want to understand what is going on. On the other hand, if this +# tag is set to NO the size of the Perl module output will be much smaller +# and Perl will parse it just the same. + +PERLMOD_PRETTY = YES + +# The names of the make variables in the generated doxyrules.make file +# are prefixed with the string contained in PERLMOD_MAKEVAR_PREFIX. +# This is useful so different doxyrules.make files included by the same +# Makefile don't overwrite each other's variables. + +PERLMOD_MAKEVAR_PREFIX = + +#--------------------------------------------------------------------------- +# Configuration options related to the preprocessor +#--------------------------------------------------------------------------- + +# If the ENABLE_PREPROCESSING tag is set to YES (the default) Doxygen will +# evaluate all C-preprocessor directives found in the sources and include +# files. + +ENABLE_PREPROCESSING = YES + +# If the MACRO_EXPANSION tag is set to YES Doxygen will expand all macro +# names in the source code. If set to NO (the default) only conditional +# compilation will be performed. Macro expansion can be done in a controlled +# way by setting EXPAND_ONLY_PREDEF to YES. + +MACRO_EXPANSION = NO + +# If the EXPAND_ONLY_PREDEF and MACRO_EXPANSION tags are both set to YES +# then the macro expansion is limited to the macros specified with the +# PREDEFINED and EXPAND_AS_PREDEFINED tags. + +EXPAND_ONLY_PREDEF = NO + +# If the SEARCH_INCLUDES tag is set to YES (the default) the includes files +# in the INCLUDE_PATH (see below) will be search if a #include is found. + +SEARCH_INCLUDES = YES + +# The INCLUDE_PATH tag can be used to specify one or more directories that +# contain include files that are not input files but should be processed by +# the preprocessor. + +INCLUDE_PATH = + +# You can use the INCLUDE_FILE_PATTERNS tag to specify one or more wildcard +# patterns (like *.h and *.hpp) to filter out the header-files in the +# directories. If left blank, the patterns specified with FILE_PATTERNS will +# be used. + +INCLUDE_FILE_PATTERNS = + +# The PREDEFINED tag can be used to specify one or more macro names that +# are defined before the preprocessor is started (similar to the -D option of +# gcc). The argument of the tag is a list of macros of the form: name +# or name=definition (no spaces). If the definition and the = are +# omitted =1 is assumed. + +PREDEFINED = + +# If the MACRO_EXPANSION and EXPAND_ONLY_PREDEF tags are set to YES then +# this tag can be used to specify a list of macro names that should be expanded. +# The macro definition that is found in the sources will be used. +# Use the PREDEFINED tag if you want to use a different macro definition. + +EXPAND_AS_DEFINED = + +# If the SKIP_FUNCTION_MACROS tag is set to YES (the default) then +# doxygen's preprocessor will remove all function-like macros that are alone +# on a line, have an all uppercase name, and do not end with a semicolon. Such +# function macros are typically used for boiler-plate code, and will confuse the +# parser if not removed. + +SKIP_FUNCTION_MACROS = YES + +#--------------------------------------------------------------------------- +# Configuration::additions related to external references +#--------------------------------------------------------------------------- + +# The TAGFILES option can be used to specify one or more tagfiles. +# Optionally an initial location of the external documentation +# can be added for each tagfile. The format of a tag file without +# this location is as follows: +# TAGFILES = file1 file2 ... +# Adding location for the tag files is done as follows: +# TAGFILES = file1=loc1 "file2 = loc2" ... +# where "loc1" and "loc2" can be relative or absolute paths or +# URLs. If a location is present for each tag, the installdox tool +# does not have to be run to correct the links. +# Note that each tag file must have a unique name +# (where the name does NOT include the path) +# If a tag file is not located in the directory in which doxygen +# is run, you must also specify the path to the tagfile here. + +TAGFILES = + +# When a file name is specified after GENERATE_TAGFILE, doxygen will create +# a tag file that is based on the input files it reads. + +GENERATE_TAGFILE = + +# If the ALLEXTERNALS tag is set to YES all external classes will be listed +# in the class index. If set to NO only the inherited external classes +# will be listed. + +ALLEXTERNALS = NO + +# If the EXTERNAL_GROUPS tag is set to YES all external groups will be listed +# in the modules index. If set to NO, only the current project's groups will +# be listed. + +EXTERNAL_GROUPS = YES + +# The PERL_PATH should be the absolute path and name of the perl script +# interpreter (i.e. the result of `which perl'). + +PERL_PATH = /usr/bin/perl + +#--------------------------------------------------------------------------- +# Configuration options related to the dot tool +#--------------------------------------------------------------------------- + +# If the CLASS_DIAGRAMS tag is set to YES (the default) Doxygen will +# generate a inheritance diagram (in HTML, RTF and LaTeX) for classes with base or +# super classes. Setting the tag to NO turns the diagrams off. Note that this +# option is superseded by the HAVE_DOT option below. This is only a fallback. It is +# recommended to install and use dot, since it yields more powerful graphs. + +CLASS_DIAGRAMS = YES + +# If set to YES, the inheritance and collaboration graphs will hide +# inheritance and usage relations if the target is undocumented +# or is not a class. + +HIDE_UNDOC_RELATIONS = YES + +# If you set the HAVE_DOT tag to YES then doxygen will assume the dot tool is +# available from the path. This tool is part of Graphviz, a graph visualization +# toolkit from AT&T and Lucent Bell Labs. The other options in this section +# have no effect if this option is set to NO (the default) + +HAVE_DOT = NO + +# If the CLASS_GRAPH and HAVE_DOT tags are set to YES then doxygen +# will generate a graph for each documented class showing the direct and +# indirect inheritance relations. Setting this tag to YES will force the +# the CLASS_DIAGRAMS tag to NO. + +CLASS_GRAPH = YES + +# If the COLLABORATION_GRAPH and HAVE_DOT tags are set to YES then doxygen +# will generate a graph for each documented class showing the direct and +# indirect implementation dependencies (inheritance, containment, and +# class references variables) of the class with other documented classes. + +COLLABORATION_GRAPH = YES + +# If the UML_LOOK tag is set to YES doxygen will generate inheritance and +# collaboration diagrams in a style similar to the OMG's Unified Modeling +# Language. + +UML_LOOK = NO + +# If set to YES, the inheritance and collaboration graphs will show the +# relations between templates and their instances. + +TEMPLATE_RELATIONS = NO + +# If the ENABLE_PREPROCESSING, SEARCH_INCLUDES, INCLUDE_GRAPH, and HAVE_DOT +# tags are set to YES then doxygen will generate a graph for each documented +# file showing the direct and indirect include dependencies of the file with +# other documented files. + +INCLUDE_GRAPH = YES + +# If the ENABLE_PREPROCESSING, SEARCH_INCLUDES, INCLUDED_BY_GRAPH, and +# HAVE_DOT tags are set to YES then doxygen will generate a graph for each +# documented header file showing the documented files that directly or +# indirectly include this file. + +INCLUDED_BY_GRAPH = YES + +# If the CALL_GRAPH and HAVE_DOT tags are set to YES then doxygen will +# generate a call dependency graph for every global function or class method. +# Note that enabling this option will significantly increase the time of a run. +# So in most cases it will be better to enable call graphs for selected +# functions only using the \callgraph command. + +CALL_GRAPH = NO + +# If the GRAPHICAL_HIERARCHY and HAVE_DOT tags are set to YES then doxygen +# will graphical hierarchy of all classes instead of a textual one. + +GRAPHICAL_HIERARCHY = YES + +# The DOT_IMAGE_FORMAT tag can be used to set the image format of the images +# generated by dot. Possible values are png, jpg, or gif +# If left blank png will be used. + +DOT_IMAGE_FORMAT = png + +# The tag DOT_PATH can be used to specify the path where the dot tool can be +# found. If left blank, it is assumed the dot tool can be found on the path. + +DOT_PATH = + +# The DOTFILE_DIRS tag can be used to specify one or more directories that +# contain dot files that are included in the documentation (see the +# \dotfile command). + +DOTFILE_DIRS = + +# The MAX_DOT_GRAPH_WIDTH tag can be used to set the maximum allowed width +# (in pixels) of the graphs generated by dot. If a graph becomes larger than +# this value, doxygen will try to truncate the graph, so that it fits within +# the specified constraint. Beware that most browsers cannot cope with very +# large images. + +MAX_DOT_GRAPH_WIDTH = 1024 + +# The MAX_DOT_GRAPH_HEIGHT tag can be used to set the maximum allows height +# (in pixels) of the graphs generated by dot. If a graph becomes larger than +# this value, doxygen will try to truncate the graph, so that it fits within +# the specified constraint. Beware that most browsers cannot cope with very +# large images. + +MAX_DOT_GRAPH_HEIGHT = 1024 + +# The MAX_DOT_GRAPH_DEPTH tag can be used to set the maximum depth of the +# graphs generated by dot. A depth value of 3 means that only nodes reachable +# from the root by following a path via at most 3 edges will be shown. Nodes that +# lay further from the root node will be omitted. Note that setting this option to +# 1 or 2 may greatly reduce the computation time needed for large code bases. Also +# note that a graph may be further truncated if the graph's image dimensions are +# not sufficient to fit the graph (see MAX_DOT_GRAPH_WIDTH and MAX_DOT_GRAPH_HEIGHT). +# If 0 is used for the depth value (the default), the graph is not depth-constrained. + +MAX_DOT_GRAPH_DEPTH = 0 + +# If the GENERATE_LEGEND tag is set to YES (the default) Doxygen will +# generate a legend page explaining the meaning of the various boxes and +# arrows in the dot generated graphs. + +GENERATE_LEGEND = YES + +# If the DOT_CLEANUP tag is set to YES (the default) Doxygen will +# remove the intermediate dot files that are used to generate +# the various graphs. + +DOT_CLEANUP = YES + +#--------------------------------------------------------------------------- +# Configuration::additions related to the search engine +#--------------------------------------------------------------------------- + +# The SEARCHENGINE tag specifies whether or not a search engine should be +# used. If set to NO the values of all tags below this one will be ignored. + +SEARCHENGINE = NO diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/g2_main.dox b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/g2_main.dox new file mode 100755 index 00000000..332a2487 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/doc/g2_main.dox @@ -0,0 +1,356 @@ + +/* this file is used mainly to hold some general g2 doxygen +documentation in the doxygen format */ + + +/* define some main groups */ + +/** + * \defgroup interface g2 User Interface + */ + +/** + * \ingroup interface + * \defgroup physdev g2 Physical devices + * + * g2 physical devices are drivers for different output + * formats. + * + */ + + + +/** \mainpage + + +\section licence License Notice + +This library is free software; you can redistribute it and/or modify +it under the terms of the GNU Lesser General Public License as +published by the Free Software Foundation; either version 2.1 of the +License, or (at your option) any later version. This library is +distributed in the hope that it will be useful, but WITHOUT ANY +WARRANTY; without even the implied warranty of MERCHANTABILITY or +FITNESS FOR A PARTICULAR PURPOSE. See the GNU Lesser General Public +License for more details. You should have received a copy of the GNU +Lesser General Public License along with this library; if not, write +to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, +Boston, MA 02111-1307 USA * + +Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner. + + +\section introduction Introduction + +\subsection what What is g2 ? + +\subsubsection short Short version (if you are in hurry) + + - 2D graphic library + - Simple to use + - Supports several types of output devices (currently X11, + PostScript, devices supported by gd http://www.boutell.com/gd/ + (PNG, JPEG), FIG (http://www.xfig.org) and MS Windows windows) + - Concept allows easy implementation of new device types + - Virtual devices allow to send output simultaneously to several devices + - User definable coordinate system + - Written in ANSI-C + - Tested under Digital Unix, AIX, Linux, VMS and Windows NT + - Perl support + - Fortran interface + +\subsubsection long Long version + +g2 is a simple to use graphics library for 2D graphical applications +written in Ansi-C. This library provides a comprehensive set of +functions for simultaneous generation of graphical output on different +types of devices. Presently, following devices are currently supported +by g2: X11, gd (PNG and JPEG), PostScript and FIG (xfig). +One major feature of the g2_library is the concept of virtual devices. +An arbitrary number of physical devices (such as PostScript, or X11) can +be grouped to create a so-called virtual device. Commands sent to such a +virtual devices will automatically issued to all attached physical +devices. This allows for example simultaneous output to a PNG file and a +Postscript file. A virtual device in turn can be attached to another +virtual device, allowing to construct trees of devices. +Virtual devices can also be useful when using different user-coordinate +systems. E.g. one X11 window showing an overview of a graphical output, +and a second window showing a zoom of a more detailed area of the +graphic. Drawing in both windows is performed by one single command to +the virtual device. + +\code + /-------> PNG: g2_attach(id_PNG,.. + ----------------------- +g2_plot---> | Virtual device: id |--------> X11: g2_attach(id_X11,... + ----------------------- + \-------> PS: g2_attach(id_PS,... +\endcode + +If you don't need or like the concept of virtual devices, simply ignore it. + + + +\section getting Getting Started + +\subsection preinstallation Preinstallation tasks: + + * PNG and JPEG support + + g2 uses the gd library by Thomas Boutell to generate PNG files. This + package is freeware (however not GPL) and can be downloaded at + http://www.boutell.com/gd/. + Linux users might prefer to install a pre-compiled gd rpm package + which should be available at your local RedHat mirrorsite. + NT users should install the gd source package in a subdirectory + named "gd" which should be located in the same directory as the g2 + subdirectory (but not in the g2 directory itself). Otherwise file + locations for gd must be modified in the g2 project workspace. + Unix and VMS users will have to build and install gd according to + the instructions found in the gd distribution. + + +\subsection installation Installation + + +LINUX + + -# Either install RPM packet with binaries, or compile as described + in the UNIX section + +UNIX + + -# Extract package with gzip -dc g2-xxxx.tar.gz | tar xvf - + -# Run './configure' + -# Optionally run 'make depend' + -# Run 'make' + -# Run 'make install' or copy libg2.a and g2.h, g2_X11.h, g2_gd.h, + anf g2_PS.h to the default locations for library and include files. + -# Optional: cd to demo directory and run 'make demo' to compile demo applications + +WINDOWS NT + + -# Extract package using either the .tar.gz or the .zip distribution + -# MS Visual C++ users can build both library and demos with the + supplied project file: g2.dsw (To obtain an icon and use menu + functions you must also build the g2res project in g2.dsw) + -# users of gcc or other commandline based compilers with make + support continue as in Unix example + -# It is also possible to compile g2 on winNT/95 using the free + cygwin32 library and a X-windows library for windows. + Theoretically it should be possible to support both X-windows and + native NT/95 windows at the same time. + +PERL (old instructions) + + -# Change to directory g2_perl + -# Perform following steps + -# perl Makefile.PL + -# make + -# make test + -# make install + -# See the \ref perl "Perl interface" section for more information + -# swig is also supported, more details are comming ... + +VMS + + -# Try to extract either the tar.gz or the zip distribution (whatever + is easier for you) + -# type mms to compile library (descrip.mms file is suplied) + -# run mms in demo directory to compile demo applications + + +\subsection simple A simple example + +The following example is a minimal application. It draws a rectangle in +a postscript file. + +\code +#include +#include + +main() +{ + int id; + id = g2_open_PS("rect.ps", g2_A4, g2_PS_land); + g2_rectangle(id, 20, 20, 150, 150); + g2_close(id); +} +\endcode + +- Always include . Additionally include header files for all +types of devices you want to use. +- Open devices using g2_open_XY functions. The open function +returns a device id of type int, which you need to refer to the device. +- Call g2_close() to close device. +- Consider turning off auto flush (g2_set_auto_flush()) for improved performance. + + +You want to draw a PNG file instead of a PostScript file ? + +replace the PS header file with + +\code +#include +\endcode + +and replace the g2_open_PS function call with + +\code +id = g2_open_gd("rect.png", 300, 200, g2_gd_png); +\endcode + +You want to draw to a PNG file and a PostScript file with one plot +command ? + +Here we use the concept of virtual devices. Open a PNG and PostScript +device, then open a virtual device and attach both the PNG and +PostScript device to the virtual device. Plot commands to the virtual +device will be issued to both PNG and PostScript device. You can attach +and detatch further devices at any time. + +\code +#include +#include +#include + +main() +{ + int id_PS,id_PNG,id; + + id_PS = g2_open_PS("rect.ps", g2_A4, g2_PS_land); + id_PNG = g2_open_gd("rect.png", 300, 200, g2_gd_png); + id = g2_open_vd(); + + g2_attach(id, id_PS); + g2_attach(id, id_PNG); + + g2_rectangle(id, 20, 20, 150, 150); + g2_circle(id, 50, 60, 100); + + g2_close(id); +} +\endcode + +Note: closing a virtual device automatically closes all attached devices. + + +\subsubsection more More examples + +More examples showing the usage of different user coordinate systems, +multiple virtual devices, etc. can be found in the distribution (demo +directory). + + +\subsection fortran Fortran interface + +The Fortran interface for g2 is currently tested for Linux and Digital +Unix/OSF. Function names for Fortran are the same as in C, however +following differences exist: + + * all variables including device IDs are of type REAL + * void functions are implemented as subroutines and must be called + with CALL + * constants defined by #define in C (e.g. g2_A4) do not work. Get + corresponding values from the apropriate header files. + +A short Fortran example: + +\code + program demo + real d,color + d=g2_open_PS('demo_f.ps', 4.0, 1.0) + call g2_plot(d, 50.0, 50.0) + call g2_string(d, 25.0, 75.0, 'TEST ') + color=g2_ink(d, 1.0, 0.0, 0.0) + write (6,*) color + call g2_pen(d, color) + call g2_circle(d, 20.0, 20.0, 10.0) + call g2_flush(d) + call g2_close(d) + stop + end +\endcode + +\subsection perl Perl interface (old info) + +The perl interface for g2 is currently tested for Linux and Digital +Unix/OSF. Function names in perl are the same as in C, however the +device itself is implemented object orientated, i.e. the device argument +is ommited in all functions. +E.g., following simple perl script: + +\code +use G2; + +$d = newX11 G2::Device(100,100); +$d->circle(10, 10, 20); +$d->string(20, 40, "Hello World"); + +print "\nDone.\n[Enter]\n"; +getc(STDIN); + +$d->close() +\endcode + +The creator functions are newX11, newGIF, newPS, etc. and accept the +same arguments as the open functions in the C version. +See the perl documentation (perldoc G2) for more details and the test.pl +script for a more extensive example. + +\section Contact + +You can contact the authors and contributors by e-mail (/ is @ and - is .): + +- Ljubomir Milanovic: ljubo/users-sourceforge-net +- Horst Wagner: wagner/users-sourceforge-net +- Tijs Michels (spline implementation): tijs/vimec-nl + +or visit g2 home page on: http://g2.sourceforge.net/ + +*/ + + + +/** \page paper PS paper sizes + + +\subsection paper PostScript paper sizes + +\code +g2 Name Name Size(Pt) +-------------------------------------------------------- +g2_A0 A0 2384 x 3370 +g2_A1 A1 1684 x 2384 +g2_A2 A2 1191 x 1684 +g2_A3 A3 842 x 1191 +g2_A4 A4 595 x 842 +g2_A5 A5 420 x 595 +g2_A6 A6 297 x 420 +g2_A7 A7 210 x 297 +g2_A8 A8 148 x 210 +g2_A9 A9 105 x 148 +g2_B0 B0 2920 x 4127 +g2_B1 B1 2064 x 2920 +g2_B2 B2 1460 x 2064 +g2_B3 B3 1032 x 1460 +g2_B4 B4 729 x 1032 +g2_B5 B5 516 x 729 +g2_B6 B6 363 x 516 +g2_B7 B7 258 x 363 +g2_B8 B8 181 x 258 +g2_B9 B9 127 x 181 +g2_B10 B10 91 x 127 +g2_Comm_10_Envelope Comm #10 Envelope 297 x 684 +g2_C5_Envelope C5 Envelope 461 x 648 +g2_DL_Envelope DL Envelope 312 x 624 +g2_Folio Folio 595 x 935 +g2_Executive Executive 522 x 756 +g2_Letter Letter 612 x 792 +g2_Legal Legal 612 x 1008 +g2_Ledger Ledger 1224 x 792 +g2_Tabloid Tabloid 792 x 1224 +\endcode + + +*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2.dsp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2.dsp new file mode 100755 index 00000000..f8c3c46d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2.dsp @@ -0,0 +1,152 @@ +# Microsoft Developer Studio Project File - Name="g2" - Package Owner=<4> +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Static Library" 0x0104 + +CFG=g2 - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "g2.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. 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To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "g2_anim.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "g2_anim.mak" CFG="g2_anim - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "g2_anim - Win32 Release" (based on "Win32 (x86) Console Application") +!MESSAGE "g2_anim - Win32 Debug" (based on "Win32 (x86) Console Application") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +RSC=rc.exe + +!IF "$(CFG)" == "g2_anim - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "Release" +# PROP BASE Intermediate_Dir "Release" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD CPP /nologo /W3 /GX /O2 /I "src/gd" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /D "WIN32" /D "NDEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD BASE RSC /l 0x409 /d "NDEBUG" +# ADD RSC /l 0x409 /d "NDEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 + +!ELSEIF "$(CFG)" == "g2_anim - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "Debug" +# PROP BASE Intermediate_Dir "Debug" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /Gm /GX /ZI /Od /D "WIN32" /D "_DEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /GZ /c +# ADD CPP /nologo /W3 /Gm /GX /ZI /Od /I "src/gd" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /D "WIN32" /D "_DEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /GZ /c +# ADD BASE RSC /l 0x409 /d "_DEBUG" +# ADD RSC /l 0x409 /d "_DEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /debug /machine:I386 /pdbtype:sept +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /debug /machine:I386 /pdbtype:sept + +!ENDIF + +# Begin Target + +# Name "g2_anim - Win32 Release" +# Name "g2_anim - Win32 Debug" +# Begin Group "Source Files" + +# PROP Default_Filter "cpp;c;cxx;rc;def;r;odl;idl;hpj;bat" +# Begin Source File + +SOURCE=.\demo\g2_anim.c +# End Source File +# End Group +# Begin Group "Header Files" + +# PROP Default_Filter "h;hpp;hxx;hm;inl" +# End Group +# Begin Group "Resource Files" + +# PROP Default_Filter "ico;cur;bmp;dlg;rc2;rct;bin;rgs;gif;jpg;jpeg;jpe" +# End Group +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Repository new file mode 100755 index 00000000..774fb0d0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/g2_perl/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Entries new file mode 100755 index 00000000..3e1d03e5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Entries @@ -0,0 +1,10 @@ +D/CVS//// +/Changes/1.1/Mon Jan 18 10:56:52 1999// +/G2.pm/1.1/Mon Apr 5 21:40:53 2004// +/G2.xs/1.1/Fri Jan 21 00:53:49 2005// +/MANIFEST/1.1/Mon Jan 18 10:56:52 1999// +/Makefile.PL.in/1.1/Mon Apr 5 21:40:53 2004// +/README/1.1/Wed Mar 10 22:23:58 2004// +/test.pl/1.1/Tue Apr 20 02:23:32 2004// +/typemap/1.1/Mon Jan 18 10:56:52 1999// +/Makefile.PL/1.1/Fri Aug 5 10:17:47 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Repository new file mode 100755 index 00000000..65251051 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/g2_perl diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Changes b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Changes new file mode 100755 index 00000000..d0b1f0a1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Changes @@ -0,0 +1,5 @@ +Revision history for Perl extension G2. + +0.01 Wed Nov 11 17:34:43 1998 + - original version; created by h2xs 1.18 + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.pm b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.pm new file mode 100755 index 00000000..fd7e511a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.pm @@ -0,0 +1,361 @@ +package G2; + +use strict; +use Carp; +use vars qw($VERSION @ISA @EXPORT @EXPORT_OK $AUTOLOAD); + +require Exporter; +require DynaLoader; +require AutoLoader; +use strict; + +@ISA = qw(Exporter DynaLoader); +# Items to export into callers namespace by default. Note: do not export +# names by default without a very good reason. Use EXPORT_OK instead. +# Do not simply export all your public functions/methods/constants. +@EXPORT = qw( + G2LD + G2_H + G2_VERSION +); +$VERSION = '0.01'; + +sub AUTOLOAD { + # This AUTOLOAD is used to 'autoload' constants from the constant() + # XS function. If a constant is not found then control is passed + # to the AUTOLOAD in AutoLoader. + + my $constname; + ($constname = $AUTOLOAD) =~ s/.*:://; + my $val = constant($constname, @_ ? $_[0] : 0); + if ($! != 0) { + if ($! =~ /Invalid/) { + $AutoLoader::AUTOLOAD = $AUTOLOAD; + goto &AutoLoader::AUTOLOAD; + } + else { + croak "Your vendor has not defined G2 macro $constname"; + } + } + eval "sub $AUTOLOAD { $val }"; + goto &$AUTOLOAD; +} + +bootstrap G2 $VERSION; + +# Preloaded methods go here. + +# Autoload methods go after =cut, and are processed by the autosplit program. + +1; +__END__ +# Below is the stub of documentation for your module. You better edit it! + +=head1 NAME + +G2 - A simple graphics library ported to Perl. + +=head1 SYNOPSIS + + use G2; + + $dev1 = newX11 G2::Device(775, 575); + $dev2 = newGD G2::Device("test.png",600,200); + + $dev1->rectangle(20,20,150,150); + $dev1->circle(100,150,60); + + $dev2->circle(100,150,60); + $dev2->string(100,50,"A circle in a PNG file"); + +=head1 DESCRIPTION + +g2 is a simple to use graphics library for 2D graphical applications. +This library provides a comprehensive set of functions for +simultaneous generation of graphical output on different types of devices. +Presently, following devices are currently supported by g2: X11, PNG, +PostScript (xfig is in developement). +One major feature of the g2_library is the concept of virtual devices. An +arbitrary number of physical devices (such as PNG, or X11) can be grouped to +create a so-called virtual device. Commands sent to such a virtual devices +will automatically issued to all attached physical devices. This allows for +example simultaneous output to a PNG file and a Postscript file. A virtual +device in turn can be attached to another virtual device, allowing to +construct trees of devices. +Virtual devices can also be useful when using different user-coordinate +systems. E.g. one X11 window showing an overview of a graphical output, and +a second window showing a zoom of a more detailed area of the graphic. +Drawing in both windows is performed by one single command to the virtual +device. +Please see g2 documentation (C interface) for up to date version. + +=head1 Exported constants + + G2LD + G2_H + G2_VERSION + + +=head1 Exported functions + +=head2 Creating new devices + +=over 5 + +=item C + +C I + +opens an X11 window with width and height of X11 window given in pixels. +returns : a new X11 device. + +=item C + +C I + +opens a new PostScript device. +file_name: name of PostScript file +paper: Paper size (e.g. g2_A4, g2_Letter). See +PostScript paper sizes for a full list of supported sizes. +orientation: paper orientation. Either g2_PS_land for +landscape or g2_PS_port for portrait +returns : a new PostScript device. + +=item C + +C I + +open a new GD device +width,height: width and height of the image in pixels +filename: name of the output file. +type: file type, 0-jpeg, 1-png +returns : a new GD device + +=item C + +C I + +Create a new Virtual Device. An arbitrary number of physical devices +(such as PNG, or X11) can be grouped to +create a so-called virtual device. Commands sent to such a virtual devices +will automatically issued to all attached physical devices. This allows for +example simultaneous output to a PNG file and a Postscript file. A virtual +device in turn can be attached to another virtual device, allowing to +construct trees of devices. +Virtual devices can also be useful when using different user-coordinate +systems. E.g. one X11 window showing an overview of a graphical output, and +a second window showing a zoom of a more detailed area of the graphic. +Drawing in both windows is performed by one single command to the virtual +device. + +=head2 Device Functions + +=item C<> + +C I + +=item C<> + +C I + +=item C<> + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=head2 Drawing Functions + + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + +=item C + +C I + Draw an ellipse on device dev + x,y: center point + r1,r2: x and y radius + +=item C + +C I + Draw a filled ellipse on device dev + x,y: center point + r1,r2: x and y radius + +=item C + +C I + +Draw an arc with center point at (x,y), x and y radius given by +r1,r2 and starting and ending angle in radians a1,a2 + +=item C + +C I + Draw a filled arc on device dev + x,y: center point + r1,r2: x and y radius + a1,a2: starting and ending angle in radians + +=item C + +C I + +=item C<> + +C I + +=item C<> + +C I + +=head1 AUTHORS + +Horst Wagner (wagner/users-sourceforge.net) and Ljubomir Milanovic (ljubo/users-sourceforge-net) + +=head1 COPYRIGHT + +Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +This file is part of the g2 library + +This library is free software; you can redistribute it and/or +modify it under the terms of the GNU Lesser General Public +License as published by the Free Software Foundation; either +version 2.1 of the License, or (at your option) any later version. + +This library is distributed in the hope that it will be useful, +but WITHOUT ANY WARRANTY; without even the implied warranty of +MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +Lesser General Public License for more details. + +You should have received a copy of the GNU Lesser General Public +License along with this library; if not, write to the Free Software +Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA + +=cut diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.xs b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.xs new file mode 100755 index 00000000..5f4d55fd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/G2.xs @@ -0,0 +1,922 @@ +#ifdef __cplusplus +extern "C" { +#endif +#include "EXTERN.h" +#include "perl.h" +#include "XSUB.h" + +#ifdef __cplusplus +} +#endif + +#include +#include + +#ifdef DO_PS +#include +#endif /* DO_PS */ + +#ifdef DO_FIG +#include +#endif /* DO_FIG */ + +#ifdef DO_X11 +#include +#endif /* DO_X11 */ + +#ifdef DO_GD +#include +#endif /* DO_GD */ + +#ifdef DO_WIN32 +#include +#endif /* DO_WIN32 */ + + +static int +not_here(s) +char *s; +{ + croak("%s not implemented on this architecture", s); + return -1; +} + +static double +constant(name, arg) +char *name; +int arg; +{ + errno = 0; + switch (*name) { + case 'A': + break; + case 'B': + break; + case 'C': + break; + case 'D': + break; + case 'E': + break; + case 'F': + break; + case 'G': + if (strEQ(name, "G2LD")) +#ifdef G2LD + return G2LD; +#else + goto not_there; +#endif + if (strEQ(name, "G2_H")) +#ifdef G2_H + return G2_H; +#else + goto not_there; +#endif + if (strEQ(name, "G2_VERSION")) +#ifdef G2_VERSION + return atof(G2_VERSION); +#else + goto not_there; +#endif + break; + case 'H': + break; + case 'I': + break; + case 'J': + break; + case 'K': + break; + case 'L': + break; + case 'M': + break; + case 'N': + break; + case 'O': + break; + case 'P': + break; + case 'Q': + break; + case 'R': + break; + case 'S': + break; + case 'T': + break; + case 'U': + break; + case 'V': + break; + case 'W': + break; + case 'X': + break; + case 'Y': + break; + case 'Z': + break; + } + errno = EINVAL; + return 0; + +not_there: + errno = ENOENT; + return 0; +} + +typedef int* DevType; +typedef DevType G2__Device; + + +MODULE = G2 PACKAGE = G2 + + +double +constant(name,arg) + char * name + int arg + +MODULE = G2 PACKAGE = G2::Device PREFIX = g2_ + +#ifdef DO_X11 + +G2::Device +g2_newX11(packname="G2::Device", width=100,height=100) + char * packname + int width + int height + PROTOTYPE: $;$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_X11(width, height); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +#endif /* DO_X11 */ + + +#ifdef DO_WIN32 + +G2::Device +g2_newWin32(packname="G2::Device", width=100,height=100,filename="Win32 window",type=0) + char * packname + int width + int height + char * filename + int type + PROTOTYPE: $;$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_win32(width, height, filename, type); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +#endif /* DO_WIN32 */ + +#ifdef DO_GD + +G2::Device +g2_newGD(packname="G2::Device", filename="g2.png", width=100, height=100, type=1) + char * packname + char * filename + int width + int height + int type + PROTOTYPE: $;$$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_gd(filename, width, height, type); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +#endif /* DO_GD */ + +#ifdef DO_PS + +G2::Device +g2_newPS(packname="G2::Device", filename="g2.ps", paper=1,orientation=1) + char * packname + char * filename + int paper + int orientation + PROTOTYPE: $;$$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_PS(filename, paper, orientation); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +G2::Device +g2_newEPSF(packname="G2::Device", filename="g2.eps") + char * packname + char * filename + PROTOTYPE: $;$$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_EPSF(filename); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +G2::Device +g2_newEPSF_CLIP(packname="G2::Device", filename="g2.eps",width=100,height=100) + char * packname + char * filename + long width + long height + PROTOTYPE: $;$$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_EPSF_CLIP(filename,width,height); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +#endif /* DO_PS */ + +#ifdef DO_FIG + +G2::Device +g2_newFIG(packname="G2::Device", filename="g2.fig") + char * packname + char * filename + PROTOTYPE: $;$$$ + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_FIG(filename); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + +#endif /* DO_FIG */ + + +G2::Device +g2_newvd(packname="G2::Device") + char * packname + PROTOTYPE: $; + CODE: + { + DevType theDevice; + theDevice = (int *)malloc(sizeof(int)); + *theDevice = g2_open_vd(); + RETVAL = theDevice; + } + OUTPUT: + RETVAL + + +void +g2_DESTROY(dev) + G2::Device dev + PROTOTYPE: $ + CODE: + { + if(g2_device_exist(*dev)) { + g2_close(*dev); + } + free(dev); + } + + +void +g2_attach(vd_dev, dev) + G2::Device vd_dev + G2::Device dev + PROTOTYPE: $ + CODE: + { + g2_attach(*vd_dev, *dev); + } + +void +g2_detach(vd_dev, dev) + G2::Device vd_dev + G2::Device dev + PROTOTYPE: $ + CODE: + { + g2_detach(*vd_dev, *dev); + } + +void +g2_close(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_close(*dev); + } + +void +g2_set_auto_flush(dev, on_off) + G2::Device dev + int on_off + PROTOTYPE: $ + CODE: + { + g2_set_auto_flush(*dev, on_off); + } + +void +g2_flush(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_flush(*dev); + } + +void +g2_save(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_save(*dev); + } + +void +g2_set_coordinate_system(dev, x_origin, y_origin, x_mul, y_mul) + G2::Device dev + double x_origin + double y_origin + double x_mul + double y_mul + PROTOTYPE: $$$$ + CODE: + { + g2_set_coordinate_system(*dev, x_origin, y_origin, x_mul, y_mul); + } + + +int +g2_ink(pd_dev, red, green, blue) + G2::Device pd_dev + double red + double green + double blue + PROTOTYPE: $$$ + CODE: + { + RETVAL = g2_ink(*pd_dev, red, green, blue); + } + OUTPUT: + RETVAL + +void +g2_pen(dev, color) + G2::Device dev + int color + PROTOTYPE: $ + CODE: + { + g2_pen(*dev, color); + } + + +void +g2_set_dash(dev, N, dashes=NULL) + G2::Device dev + int N + double * dashes + PROTOTYPE: $ + CODE: + { + g2_set_dash(*dev, N, dashes); + free(dashes); + } + +void +g2_set_font_size(dev, size) + G2::Device dev + double size + PROTOTYPE: $ + CODE: + { + g2_set_font_size(*dev, size); + } + +void +g2_set_line_width(dev, w) + G2::Device dev + double w + PROTOTYPE: $ + CODE: + { + g2_set_line_width(*dev, w); + } + +void +g2_clear_palette(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_clear_palette(*dev); + } + +void +g2_reset_palette(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_reset_palette(*dev); + } + +void +g2_allocate_basic_colors(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_allocate_basic_colors(*dev); + } + +void +g2_clear(dev) + G2::Device dev + PROTOTYPE: + CODE: + { + g2_clear(*dev); + } + +void +g2_set_background(dev, color) + G2::Device dev + int color + PROTOTYPE: $ + CODE: + { + g2_set_background(*dev, color); + } + +void +g2_move(dev, x, y) + G2::Device dev + double x + double y + PROTOTYPE: $$ + CODE: + { + g2_move(*dev, x, y); + } + +void +g2_move_r(dev, dx, dy) + G2::Device dev + double dx + double dy + PROTOTYPE: $$ + CODE: + { + g2_move_r(*dev, dx, dy); + } + +void +g2_plot(dev, x, y) + G2::Device dev + double x + double y + PROTOTYPE: $$ + CODE: + { + g2_plot(*dev, x, y); + } + +void +g2_plot_r(dev, dx, dy) + G2::Device dev + double dx + double dy + PROTOTYPE: $$ + CODE: + { + g2_plot_r(*dev, dx, dy); + } + + + +void +g2_line(dev, x1, y1, x2, y2) + G2::Device dev + double x1 + double y1 + double x2 + double y2 + + PROTOTYPE: $$$$ + CODE: + { + g2_line(*dev, x1, y1, x2, y2); + } + +void +g2_line_r(dev, dx, dy) + G2::Device dev + double dx + double dy + PROTOTYPE: $$ + CODE: + { + g2_line_r(*dev, dx, dy); + } + +void +g2_line_to(dev, x, y) + G2::Device dev + double x + double y + PROTOTYPE: $$ + CODE: + { + g2_line_to(*dev, x, y); + } + +void +g2_poly_line(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_poly_line(*dev, N_pt, points); + free(points); + } + +void +g2_triangle(dev, x1, y1, x2, y2, x3, y3) + G2::Device dev + double x1 + double y1 + double x2 + double y2 + double x3 + double y3 + PROTOTYPE: $$$$$$$ + CODE: + { + g2_triangle(*dev, x1, y1, x2, y2, x3, y3); + } + + +void +g2_filled_triangle(dev, x1, y1, x2, y2, x3, y3) + G2::Device dev + double x1 + double y1 + double x2 + double y2 + double x3 + double y3 + PROTOTYPE: $$$$$$$ + CODE: + { + g2_filled_triangle(*dev, x1, y1, x2, y2, x3, y3); + } + +void +g2_rectangle(dev, x1, y1, x2, y2) + G2::Device dev + double x1 + double y1 + double x2 + double y2 + PROTOTYPE: $$$$ + CODE: + { + g2_rectangle(*dev, x1, y1, x2, y2); + } + + +void +g2_filled_rectangle(dev, x1, y1, x2, y2) + G2::Device dev + double x1 + double y1 + double x2 + double y2 + PROTOTYPE: $$$$ + CODE: + { + g2_filled_rectangle(*dev, x1, y1, x2, y2); + } + +void +g2_polygon(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_polygon(*dev, N_pt, points); + free(points); + } + +void +g2_filled_polygon(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_filled_polygon(*dev, N_pt, points); + free(points); + } + +void +g2_circle(dev, x, y, r) + G2::Device dev + double x + double y + double r + PROTOTYPE: $$$ + CODE: + { + g2_circle(*dev, x, y, r); + } + +void +g2_filled_circle(dev, x, y, r) + G2::Device dev + double x + double y + double r + PROTOTYPE: $$$ + CODE: + { + g2_filled_circle(*dev, x, y, r); + } + +void +g2_ellipse(dev, x, y, r1, r2) + G2::Device dev + double x + double y + double r1 + double r2 + PROTOTYPE: $$$$ + CODE: + { + g2_ellipse(*dev, x, y, r1, r2); + } + +void +g2_filled_ellipse(dev, x, y, r1, r2) + G2::Device dev + double x + double y + double r1 + double r2 + PROTOTYPE: $$$$ + CODE: + { + g2_filled_ellipse(*dev, x, y, r1, r2); + } + +void +g2_arc(dev, x, y, r1, r2, a1, a2) + G2::Device dev + double x + double y + double r1 + double r2 + double a1 + double a2 + PROTOTYPE: $$$$$$ + CODE: + { + g2_arc(*dev, x, y, r1, r2, a1, a2); + } + +void +g2_filled_arc(dev, x, y, r1, r2, a1, a2) + G2::Device dev + double x + double y + double r1 + double r2 + double a1 + double a2 + PROTOTYPE: $$$$$$ + CODE: + { + g2_filled_arc(*dev, x, y, r1, r2, a1, a2); + } + +void +g2_string(dev, x, y, text) + G2::Device dev + double x + double y + char * text + PROTOTYPE: $$$ + CODE: + { + g2_string(*dev, x, y, text); + } + +void +g2_set_QP(dev, d, shape) + G2::Device dev + double d + enum QPshape shape + PROTOTYPE: $$ + CODE: + { + g2_set_QP(*dev, d, shape); + } + +void +g2_plot_QP(dev, x, y) + G2::Device dev + double x + double y + PROTOTYPE: $$ + CODE: + { + g2_plot_QP(*dev, x, y); + } + +void +g2_query_pointer(dev) + G2::Device dev + PROTOTYPE: $$ + CODE: + { + double x, y; + unsigned int button; + g2_query_pointer(*dev, &x, &y, &button); + } + + + + + +void +g2_spline(dev, N_pt, points, o) + G2::Device dev + int N_pt + double * points + int o + PROTOTYPE: $$ + CODE: + { + g2_spline(*dev, N_pt, points, o); + free(points); + } + + +void +g2_b_spline(dev, N_pt, points, o) + G2::Device dev + int N_pt + double * points + int o + PROTOTYPE: $$ + CODE: + { + g2_b_spline(*dev, N_pt, points, o); + free(points); + } + + +void +g2_raspln(dev, N_pt, points, tn) + G2::Device dev + int N_pt + double * points + double tn + PROTOTYPE: $$ + CODE: + { + g2_raspln(*dev, N_pt, points, tn); + free(points); + } + + +void +g2_para_3(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_para_3(*dev, N_pt, points); + free(points); + } + + +void +g2_para_5(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_para_5(*dev, N_pt, points); + free(points); + } + + +void +g2_filled_spline(dev, N_pt, points, o) + G2::Device dev + int N_pt + double * points + int o + PROTOTYPE: $$ + CODE: + { + g2_filled_spline(*dev, N_pt, points, o); + free(points); + } + + +void +g2_filled_b_spline(dev, N_pt, points, o) + G2::Device dev + int N_pt + double * points + int o + PROTOTYPE: $$ + CODE: + { + g2_filled_b_spline(*dev, N_pt, points, o); + free(points); + } + + +void +g2_filled_raspln(dev, N_pt, points, tn) + G2::Device dev + int N_pt + double * points + double tn + PROTOTYPE: $$ + CODE: + { + g2_filled_raspln(*dev, N_pt, points, tn); + free(points); + } + + +void +g2_filled_para_3(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_filled_para_3(*dev, N_pt, points); + free(points); + } + + +void +g2_filled_para_5(dev, N_pt, points) + G2::Device dev + int N_pt + double * points + PROTOTYPE: $$ + CODE: + { + g2_filled_para_5(*dev, N_pt, points); + free(points); + } diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/MANIFEST b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/MANIFEST new file mode 100755 index 00000000..3e434f1a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/MANIFEST @@ -0,0 +1,7 @@ +Changes +G2.pm +G2.xs +MANIFEST +Makefile.PL +test.pl +typemap diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL new file mode 100755 index 00000000..e870d2a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL @@ -0,0 +1,10 @@ +use ExtUtils::MakeMaker; +# See lib/ExtUtils/MakeMaker.pm for details of how to influence +# the contents of the Makefile that is written. +WriteMakefile( + 'NAME' => 'G2', + 'VERSION_FROM' => 'G2.pm', # finds $VERSION + 'LIBS' => ['-L./.. -lg2 -L/usr/X11R6/lib64 -L/usr/local/lib -lm -lX11 -lgd'], # e.g., '-lm' + 'DEFINE' => '-DPACKAGE_NAME=\"\" -DPACKAGE_TARNAME=\"\" -DPACKAGE_VERSION=\"\" -DPACKAGE_STRING=\"\" -DPACKAGE_BUGREPORT=\"\" -DLINUX=1 -DDO_PS=1 -DDO_FIG=1 -DDO_X11=1 -DDO_GD=1 -DSTDC_HEADERS=1 -DHAVE_SYS_TYPES_H=1 -DHAVE_SYS_STAT_H=1 -DHAVE_STDLIB_H=1 -DHAVE_STRING_H=1 -DHAVE_MEMORY_H=1 -DHAVE_STRINGS_H=1 -DHAVE_INTTYPES_H=1 -DHAVE_STDINT_H=1 -DHAVE_UNISTD_H=1 -DHAVE_LIMITS_H=1 ', # e.g., '-DHAVE_SOMETHING' + 'INC' => '-I./../include', # e.g., '-I/usr/local/include' +); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL.in new file mode 100755 index 00000000..14c5a634 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/Makefile.PL.in @@ -0,0 +1,10 @@ +use ExtUtils::MakeMaker; +# See lib/ExtUtils/MakeMaker.pm for details of how to influence +# the contents of the Makefile that is written. +WriteMakefile( + 'NAME' => 'G2', + 'VERSION_FROM' => 'G2.pm', # finds $VERSION + 'LIBS' => ['-L./.. -lg2 @LDFLAGS@'], # e.g., '-lm' + 'DEFINE' => '@DEFS@', # e.g., '-DHAVE_SOMETHING' + 'INC' => '-I./../include', # e.g., '-I/usr/local/include' +); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/README b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/README new file mode 100755 index 00000000..fbde50c7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/README @@ -0,0 +1,11 @@ + +To build g2 perl module: + +perl Makefile.PL +make + +Inspect test.pl and comment out unsupported devices. + +make test +make install + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/test.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/test.pl new file mode 100755 index 00000000..8a6304a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/test.pl @@ -0,0 +1,213 @@ +# Before `make install' is performed this script should be runnable with +# `make test'. After `make install' it should work as `perl test.pl' + +######################### We start with some black magic to print on failure. + +# Change 1..1 below to 1..last_test_to_print . +# (It may become useful if the test is moved to ./t subdirectory.) + +BEGIN { $| = 1; print "1..1\n"; } +END {print "not ok 1\n" unless $loaded;} +use G2; + +$loaded = 1; +print "ok 1\n"; + +######################### End of black magic. + +# Insert your test code below (better if it prints "ok 13" +# (correspondingly "not ok 13") depending on the success of chunk 13 +# of the test code): + +$d = newvd G2::Device(); + +#PS +if ($d->can(newPS)) + { + $dev[0] = newPS G2::Device("test.ps", 4, 0); + $d->attach($dev[0]); + } +else + { + print "Not supported: PS\n"; + } + + +#FIG +if ($d->can(newFIG)) + { + $dev[1] = newFIG G2::Device("test.fig"); + $d->attach($dev[1]); +} +else + { + print "Not supported: FIG\n"; + } + + +#X11 +if ($d->can(newX11)) + { + $dev[2] = newX11 G2::Device(775, 575); + $d->attach($dev[2]); + } +else + { + print "Not supported: X11\n"; + } + + +#Win32 +if ($d->can(newWin32)) + { + $dev[2] = newWin32 G2::Device(775, 575); + $d->attach($dev[2]); + } +else + { + print "Not supported: Win32\n"; + } + +#GD +if ($d->can(newGD)) + { + $dev[3] = newGD G2::Device("test.png", 775, 575, 1); + $d->attach($dev[3]); + } +else + { + print "Not supported: GD\n"; + } + +$d->set_auto_flush(0); + +for($i=0;$i<27;$i++) { + $d->pen($i); + $d->filled_circle($i*20+10, 10, 10); + $d->pen(1); + $d->circle($i*20+10, 10, 10); + $str = sprintf("%d", $i); + $d->string($i*20+7, 21, $str); + } + +for($j=0;$j<$#dev;$j++) + { + if($dev[$j] > 0) + { + for($i=0;$i<=64;$i++) { + $dev[$j]->move( 2*$i+575, 5); + $dev[$j]->pen($dev[$j]->ink($i/64., 0, 0)); + $dev[$j]->line_r(0, 20); + $dev[$j]->pen($dev[$j]->ink(0, $i/64., 0)); + $dev[$j]->line_r(10, 20); + $dev[$j]->pen($dev[$j]->ink(0, 0, $i/64.)); + $dev[$j]->line_r(-10, 20); + } + } + } + + $d->pen(1); + $d->line(200, 50, 350, 50); + $d->line(200, 48, 350, 48); + $d->line(200, 46, 350, 46); + $d->line(200, 46, 200, 75); + $d->line(198, 46, 198, 75); + $d->line(196, 46, 196, 75); + $d->string(200, 50, "012abcABC#())(\\-+~*!$%&"); + $d->pen(1); + for($i=1;$i<25;$i++) { + $d->line(15, $i*20+50, 15, $i*20+50+$i); + $d->set_font_size(12); + $str = sprintf("%2d:", $i); + $d->string(20, $i*20+50, $str); + $d->set_font_size($i); + $d->string(40, $i*20+50, "hello, world"); + } + + $d->plot(150, 70); + $d->line(147, 68, 153, 68); + + $y=100; + $d->line(120, $y, 170, $y+50); + $d->triangle(150, $y, 250, $y, 200, $y+50); + $d->rectangle(300, $y, 400, $y+50); + $d->circle(450, $y+25, 25); + $d->ellipse(550, $y+25, 45, 25); + $d->arc(650, $y+25, 25, 45, 90, 360); + + $pts[0]=4; + $pts[1]=4; + $d->set_dash(2, \@pts); + $d->line(120+5, $y, 170+5, $y+50); + $d->triangle(150+10, $y+4, 250-10, $y+4, 200, $y+50-5); + $d->rectangle(305, $y+5, 395, $y+50-5); + $d->circle(450, $y+25, 20); + $d->ellipse(550, $y+25, 40, 20); + $d->arc(650, $y+25, 20, 40, 90, 360); + $d->set_dash(0); + + $y=200; + $d->filled_triangle(150, $y, 250, $y, 200, $y+50); + $d->filled_rectangle(300, $y, 400, $y+50); + $d->filled_circle(450, $y+25, 25); + $d->filled_ellipse(550, $y+25, 45, 25); + $d->filled_arc(650, $y+25, 25, 45, 90, 360); + + $y=300.; + $pts[0]=150.; $pts[1]=$y; + $pts[2]=175.; $pts[3]=$y+100.; + $pts[4]=200.; $pts[5]=$y; + $pts[6]=225.; $pts[7]=$y+100.; + $pts[8]=250.; $pts[9]=$y; + $d->poly_line(5, \@pts); + $d->pen(19); + $d->b_spline(5, \@pts, 20); + $d->pen(1); + + $pts[0]=300; $pts[1]=$y; + $pts[2]=350; $pts[3]=$y; + $pts[4]=375; $pts[5]=$y+50; + $pts[6]=325; $pts[7]=$y+90; + $pts[8]=275; $pts[9]=$y+50; + $d->polygon(5, \@pts); + + $pts[0]=450; $pts[1]=$y; + $pts[2]=500; $pts[3]=$y; + $pts[4]=525; $pts[5]=$y+50; + $pts[6]=475; $pts[7]=$y+90; + $pts[8]=425; $pts[9]=$y+50; + $d->filled_polygon(5, \@pts); + + + $d->line(225, 448, 200+19*25, 448); + for($i=1;$i<20;$i++) { + $d->pen($i+1); + $d->set_line_width($i); + $d->move(200+$i*25, 450); + $d->line_to(200+$i*25, 550); + } + $d->pen(1); + + $d->set_line_width(5); + for($i=1;$i<10;$i++) { + $pts[0]=1*$i; + $pts[1]=2*$i; + $pts[2]=3*$i; + $d->set_dash(3, \@pts); + $d->line(550, 300+$i*8, 750, 350+$i*8); + } + + $d->set_dash(0); + $d->set_line_width(5); + $d->arc(740, 180, 25, 100, -45+15, -45-15); + $d->filled_arc(740, 180, 12, 50, -45+15, -45-15); + + $d->set_line_width(1); + $d->circle(400, 400, 20); + $d->ellipse(400, 400, 25, 25); + $d->arc(400, 400, 30, 30, 0, 360); + + $d->flush; + print "\nDone.\n[Enter]\n"; + getc(STDIN); + $d->close(); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/typemap b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/typemap new file mode 100755 index 00000000..837edca5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2_perl/typemap @@ -0,0 +1,28 @@ +enum QPshape T_PTROBJ +G2::Device T_PTROBJ +double * T_dbl_array + +INPUT +T_dbl_array + { + AV *tempav; + I32 len; + int i; + SV **tv; + if (!SvROK($arg)) { + croak(\"$arg is not a reference.\"); + } + if (SvTYPE(SvRV($arg)) != SVt_PVAV) { + croak(\"$arg is not an array.\"); + } + tempav = (AV*)SvRV($arg); + len = av_len(tempav)+1; + $var = (double *) malloc(len*sizeof(double)); + for (i=0;i +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Console Application" 0x0103 + +CFG=g2demo - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "g2demo.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "g2demo.mak" CFG="g2demo - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "g2demo - Win32 Release" (based on "Win32 (x86) Console Application") +!MESSAGE "g2demo - Win32 Debug" (based on "Win32 (x86) Console Application") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +RSC=rc.exe + +!IF "$(CFG)" == "g2demo - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "Release" +# PROP BASE Intermediate_Dir "Release" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Ignore_Export_Lib 0 +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD CPP /nologo /MD /W3 /GX /O2 /I "src/GIF" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /I "src/FIG" /D "NDEBUG" /D "G2DLL" /D "DO_GIF" /D "_CONSOLE" /D "_MBCS" /D "WIN32" /D "DO_PS" /D "DO_FIG" /D "DO_WIN32" /D "DO_WMF32" /D "DO_EPSF" /YX /FD /c +# ADD BASE RSC /l 0x409 /d "NDEBUG" +# ADD RSC /l 0x409 /d "NDEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 /libpath:"./Release" +# SUBTRACT LINK32 /verbose + +!ELSEIF "$(CFG)" == "g2demo - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "g2demo__" +# PROP BASE Intermediate_Dir "g2demo__" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Ignore_Export_Lib 0 +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /Gm /GX /Zi /Od /D "WIN32" /D "_DEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD CPP /nologo /MD /W3 /Gm /GX /ZI /Od /I "src/gd" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /I "src/FIG" /D "_DEBUG" /D "DO_GD" /D "DO_EPSF_CLIP" /D "_CONSOLE" /D "_MBCS" /D "WIN32" /D "DO_PS" /D "DO_FIG" /D "DO_WIN32" /D "DO_WMF32" /D "DO_EPSF" /FR /YX /FD /c +# ADD BASE RSC /l 0x409 /d "_DEBUG" +# ADD RSC /l 0x409 /fo"g2_win32.res" /d "_DEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /debug /machine:I386 /pdbtype:sept +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /incremental:no /debug /machine:I386 /pdbtype:sept /libpath:"./Debug" /libpath:"../gd" + +!ENDIF + +# Begin Target + +# Name "g2demo - Win32 Release" +# Name "g2demo - Win32 Debug" +# Begin Source File + +SOURCE=.\demo\g2_test.c +# End Source File +# Begin Source File + +SOURCE=..\gdwin32\bgd.lib +# End Source File +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2dll.dsp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2dll.dsp new file mode 100755 index 00000000..b3009e64 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2dll.dsp @@ -0,0 +1,161 @@ +# Microsoft Developer Studio Project File - Name="g2dll" - Package Owner=<4> +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Dynamic-Link Library" 0x0102 + +CFG=g2dll - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "g2dll.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "g2dll.mak" CFG="g2dll - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "g2dll - Win32 Release" (based on "Win32 (x86) Dynamic-Link Library") +!MESSAGE "g2dll - Win32 Debug" (based on "Win32 (x86) Dynamic-Link Library") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +MTL=midl.exe +RSC=rc.exe + +!IF "$(CFG)" == "g2dll - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "Release" +# PROP BASE Intermediate_Dir "Release" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /MT /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /D "_MBCS" /D "_USRDLL" /D "G2DLL_EXPORTS" /YX /FD /c +# ADD CPP /nologo /MT /W3 /GX /O2 /I "../gd" /I "./src" /I "../src" /D "NDEBUG" /D "MAKEDLL" /D "G2DLL" /D "WIN32" /D "_WINDOWS" /D "_MBCS" /D "_USRDLL" /D "G2DLL_EXPORTS" /YX /FD /c +# ADD BASE MTL /nologo /D "NDEBUG" /mktyplib203 /win32 +# ADD MTL /nologo /D "NDEBUG" /mktyplib203 /win32 +# ADD BASE RSC /l 0x409 /d "NDEBUG" +# ADD RSC /l 0x409 /d "NDEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /dll /machine:I386 +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /dll /machine:I386 + +!ELSEIF "$(CFG)" == "g2dll - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "g2dll___Win32_Debug" +# PROP BASE Intermediate_Dir "g2dll___Win32_Debug" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /MTd /W3 /Gm /GX /ZI /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /D "_MBCS" /D "_USRDLL" /D "G2DLL_EXPORTS" /YX /FD /GZ /c +# ADD CPP /nologo /MD /W3 /Gm /GX /ZI /Od /I "../gd" /I "./src" /I "../src" /D "_DEBUG" /D "MAKEDLL" /D "G2DLL" /D "WIN32" /D "_WINDOWS" /D "_MBCS" /D "_USRDLL" /D "G2DLL_EXPORTS" /YX /FD /GZ /c +# ADD BASE MTL /nologo /D "_DEBUG" /mktyplib203 /win32 +# ADD MTL /nologo /D "_DEBUG" /mktyplib203 /win32 +# ADD BASE RSC /l 0x409 /d "_DEBUG" +# ADD RSC /l 0x409 /d "_DEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /dll /debug /machine:I386 /pdbtype:sept +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /dll /debug /machine:I386 /pdbtype:sept + +!ENDIF + +# Begin Target + +# Name "g2dll - Win32 Release" +# Name "g2dll - Win32 Debug" +# Begin Group "Source Files" + +# PROP Default_Filter "cpp;c;cxx;rc;def;r;odl;idl;hpj;bat" +# Begin Source File + +SOURCE=.\src\g2_control_pd.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_device.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_fif.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_graphic_pd.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_physical_device.c +# End Source File +# Begin Source File + +SOURCE=.\src\PS\g2_PS.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_splines.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_ui_control.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_ui_device.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_ui_graphic.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_ui_virtual_device.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_util.c +# End Source File +# Begin Source File + +SOURCE=.\src\g2_virtual_device.c +# End Source File +# Begin Source File + +SOURCE=.\src\Win32\g2_win32.c +# End Source File +# Begin Source File + +SOURCE=.\src\Win32\g2_win32_thread.c +# End Source File +# End Group +# Begin Group "Header Files" + +# PROP Default_Filter "h;hpp;hxx;hm;inl" +# End Group +# Begin Group "Resource Files" + +# PROP Default_Filter "ico;cur;bmp;dlg;rc2;rct;bin;rgs;gif;jpg;jpeg;jpe" +# End Group +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2res.dsp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2res.dsp new file mode 100755 index 00000000..ee971c2f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/g2res.dsp @@ -0,0 +1,101 @@ +# Microsoft Developer Studio Project File - Name="g2res" - Package Owner=<4> +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Dynamic-Link Library" 0x0102 + +CFG=g2res - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "g2res.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "g2res.mak" CFG="g2res - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "g2res - Win32 Release" (based on "Win32 (x86) Dynamic-Link Library") +!MESSAGE "g2res - Win32 Debug" (based on "Win32 (x86) Dynamic-Link Library") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +MTL=midl.exe +RSC=rc.exe + +!IF "$(CFG)" == "g2res - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "g2res__0" +# PROP BASE Intermediate_Dir "g2res__0" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /MT /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /YX /FD /c +# ADD CPP /nologo /MT /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /YX /FD /c +# ADD BASE MTL /nologo /D "NDEBUG" /mktyplib203 /o "NUL" /win32 +# ADD MTL /nologo /D "NDEBUG" /mktyplib203 /o "NUL" /win32 +# ADD BASE RSC /l 0x409 /d "NDEBUG" +# ADD RSC /l 0x409 /d "NDEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:windows /dll /machine:I386 +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:windows /dll /machine:I386 + +!ELSEIF "$(CFG)" == "g2res - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "g2res__1" +# PROP BASE Intermediate_Dir "g2res__1" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /MTd /W3 /Gm /GX /Zi /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /YX /FD /c +# ADD CPP /nologo /MD /W3 /Gm /GX /ZI /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /YX /FD /c +# ADD BASE MTL /nologo /D "_DEBUG" /mktyplib203 /o "NUL" /win32 +# ADD MTL /nologo /D "_DEBUG" /mktyplib203 /o "NUL" /win32 +# ADD BASE RSC /l 0x409 /d "_DEBUG" +# ADD RSC /l 0x409 /d "_DEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:windows /dll /debug /machine:I386 /pdbtype:sept +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:windows /dll /debug /machine:I386 /pdbtype:sept + +!ENDIF + +# Begin Target + +# Name "g2res - Win32 Release" +# Name "g2res - Win32 Debug" +# Begin Source File + +SOURCE=.\src\Win32\g2_Win32.ico +# End Source File +# Begin Source File + +SOURCE=.\src\Win32\g2_win32.rc +# End Source File +# Begin Source File + +SOURCE=.\src\Win32\g2res.c +# End Source File +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/gd.dsp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/gd.dsp new file mode 100755 index 00000000..a4b3abec --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/gd.dsp @@ -0,0 +1,108 @@ +# Microsoft Developer Studio Project File - Name="gd" - Package Owner=<4> +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Static Library" 0x0104 + +CFG=gd - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "gd.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "gd.mak" CFG="gd - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "gd - Win32 Release" (based on "Win32 (x86) Static Library") +!MESSAGE "gd - Win32 Debug" (based on "Win32 (x86) Static Library") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +RSC=rc.exe + +!IF "$(CFG)" == "gd - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "Release" +# PROP BASE Intermediate_Dir "Release" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /YX /FD /c +# ADD CPP /nologo /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /YX /FD /c +# ADD BASE RSC /l 0x409 +# ADD RSC /l 0x409 +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LIB32=link.exe -lib +# ADD BASE LIB32 /nologo +# ADD LIB32 /nologo + +!ELSEIF "$(CFG)" == "gd - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "gd___Win" +# PROP BASE Intermediate_Dir "gd___Win" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /GX /Z7 /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /YX /FD /c +# ADD CPP /nologo /W3 /GX /Z7 /Od /I "../../../gd1.3" /I "./src" /I "../src" /D "_WINDOWS" /D "WIN32" /D "_DEBUG" /YX /FD /c +# ADD BASE RSC /l 0x409 +# ADD RSC /l 0x409 +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LIB32=link.exe -lib +# ADD BASE LIB32 /nologo +# ADD LIB32 /nologo + +!ENDIF + +# Begin Target + +# Name "gd - Win32 Release" +# Name "gd - Win32 Debug" +# Begin Source File + +SOURCE=..\gd\gd.c +# End Source File +# Begin Source File + +SOURCE=..\gd\gdfontg.c +# End Source File +# Begin Source File + +SOURCE=..\gd\gdfontl.c +# End Source File +# Begin Source File + +SOURCE=..\gd\gdfontmb.c +# End Source File +# Begin Source File + +SOURCE=..\gd\gdfonts.c +# End Source File +# Begin Source File + +SOURCE=..\gd\gdfontt.c +# End Source File +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Repository new file mode 100755 index 00000000..7a693e0b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/include diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2.h new file mode 100755 index 00000000..e16a9229 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2.h @@ -0,0 +1,200 @@ +/***************************************************************************** +** Copyright (C) 1998-2005 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_H +#define _G2_H + + +/* g2 version */ +#define G2_VERSION "0.70" + + +#if defined(__cplusplus) +extern "C" +{ +#endif + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#pragma message( "Building DLL library") +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + + +#define G2LD g2_ld() + +#if defined(SWIG) +#if defined(DO_X11) +%include "X11/g2_X11.h" +#endif +#if defined(DO_PS) +%include "PS/g2_PS.h" +#endif +#if defined(DO_GD) +%include "GD/g2_gd.h" +#endif +#if defined(DO_WIN32) +%include "WIN32/g2_win32.h" +#endif + +%module g2 + +%include typemaps.i + +%{ +#include "g2.h" +#if defined(DO_X11) +#include "g2_X11.h" +#endif +#if defined(DO_PS) +#include "g2_PS.h" +#endif +#if defined(DO_GD) +#include "g2_gd.h" +#endif +#if defined(DO_WIN32) +#include "WIN32/g2_win32.h" +#endif +%} + +#endif +/* end SWIG */ + + +enum QPshape { + QPrect, /**< rectangular quasi pixel */ + QPcirc /**< circle as a quasi pixel */ +}; + +/* compatibility with old versions */ +#define g2_draw_string(dev, x, y, text) g2_string((dev), (x), (y), (text)) + + + +G2L int g2_open_vd(void); +G2L void g2_attach(int vd_dev, int dev); +G2L void g2_detach(int vd_dev, int dev); + +G2L void g2_close(int dev); +G2L void g2_set_auto_flush(int dev, int on_off); +G2L void g2_flush(int dev); +G2L void g2_save(int dev); +G2L void g2_set_coordinate_system(int dev, double x_origin, double y_origin, + double x_mul, double y_mul); + +G2L int g2_ld(); +G2L void g2_set_ld(int dev); + +G2L int g2_ink(int pd_dev, double red, double green, double blue); +G2L void g2_pen(int dev, int color); +G2L void g2_set_dash(int dev, int N, double *dashes); +G2L void g2_set_font_size(int dev, double size); +G2L void g2_set_line_width(int dev, double w); +G2L void g2_clear_palette(int dev); +G2L void g2_reset_palette(int dev); +G2L void g2_allocate_basic_colors(int dev); + +G2L void g2_clear(int dev); +G2L void g2_set_background(int dev, int color); + +G2L void g2_move(int dev, double x, double y); +G2L void g2_move_r(int dev, double dx, double dy); + +G2L void g2_plot(int dev, double x, double y); +G2L void g2_plot_r(int dev, double dx, double dy); +G2L void g2_line(int dev, double x1, double y1, double x2, double y2); +G2L void g2_line_r(int dev, double dx, double dy); +G2L void g2_line_to(int dev, double x, double y); +G2L void g2_poly_line(int dev, int N_pt, double *points); +G2L void g2_triangle(int dev, double x1, double y1, + double x2, double y2, + double x3, double y3); +G2L void g2_filled_triangle(int dev, double x1, double y1, + double x2, double y2, + double x3, double y3); +G2L void g2_rectangle(int dev, double x1, double y1, double x2, double y2); +G2L void g2_filled_rectangle(int dev, + double x1, double y1, double x2, double y2); +G2L void g2_polygon(int dev, int N_pt, double *points); +G2L void g2_filled_polygon(int dev, int N_pt, double *points); +G2L void g2_circle(int dev, double x, double y, double r); +G2L void g2_filled_circle(int dev, double x, double y, double r); +G2L void g2_ellipse(int dev, double x, double y, double r1, double r2); +G2L void g2_filled_ellipse(int dev, double x, double y, double r1, double r2); +G2L void g2_arc(int dev, + double x, double y, + double r1, double r2, + double a1, double a2); +G2L void g2_filled_arc(int dev, double x, double y, + double r1, double r2, + double a1, double a2); +G2L void g2_string(int dev, double x, double y, const char *text); +G2L void g2_image(int dev, + double x, double y, int x_size, int y_size, int *pens); + +G2L void g2_set_QP(int dev, double d, enum QPshape shape); +G2L void g2_plot_QP(int dev, double x, double y); +#if !defined(SWIG) +G2L void g2_query_pointer(int dev, double *x, double *y, unsigned int *button); +#else +extern void g2_query_pointer(int dev, double *OUTPUT,double *OUTPUT,unsigned int *OUTPUT); +#endif + + + /* Tijs Michels */ + /* 06/16/99 */ + +G2L void g2_spline(int id, int n, double *points, int o); +G2L void g2_b_spline(int id, int n, double *points, int o); +G2L void g2_raspln(int id, int n, double *points, double tn); +G2L void g2_para_3(int id, int n, double *points); +G2L void g2_para_5(int id, int n, double *points); +G2L void g2_filled_spline(int id, int n, double *points, int o); +G2L void g2_filled_b_spline(int id, int n, double *points, int o); +G2L void g2_filled_raspln(int id, int n, double *points, double tn); +G2L void g2_filled_para_3(int id, int n, double *points); +G2L void g2_filled_para_5(int id, int n, double *points); + + +/** Actualy private function, but... **/ +G2L int g2_device_exist(int dix); + +/** Use only if you know what are you doing **/ +#define G2_PD_HANDLES_SIZE 32 +G2L void g2_get_pd_handles(int pd, void *handles[G2_PD_HANDLES_SIZE]); + + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_FIG.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_FIG.h new file mode 100755 index 00000000..908d8f38 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_FIG.h @@ -0,0 +1,54 @@ +/***************************************************************************** +** Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_FIG_H +#define _G2_FIG_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + +G2L int g2_open_FIG(const char *file_name); + + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_FIG_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_PS.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_PS.h new file mode 100755 index 00000000..88eb918c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/include/g2_PS.h @@ -0,0 +1,118 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_PS_H +#define _G2_PS_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + +/** + * g2 paper type. + * + * \ingroup PS + */ +enum g2_PS_paper { /* Name Size(Pt) */ + g2_A0, /**< A0 2384 x 3370 */ + g2_A1, /**< A1 1684 x 2384 */ + g2_A2, /**< A2 1191 x 1684 */ + g2_A3, /**< A3 842 x 1191 */ + g2_A4, /**< A4 595 x 842 */ + g2_A5, /**< A5 420 x 595 */ + g2_A6, /**< A6 297 x 420 */ + g2_A7, /**< A7 210 x 297 */ + g2_A8, /**< A8 148 x 210 */ + g2_A9, /**< A9 105 x 148 */ + g2_B0, /**< B0 2920 x 4127 */ + g2_B1, /**< B1 2064 x 2920 */ + g2_B2, /**< B2 1460 x 2064 */ + g2_B3, /**< B3 1032 x 1460 */ + g2_B4, /**< B4 729 x 1032 */ + g2_B5, /**< B5 516 x 729 */ + g2_B6, /**< B6 363 x 516 */ + g2_B7, /**< B7 258 x 363 */ + g2_B8, /**< B8 181 x 258 */ + g2_B9, /**< B9 127 x 181 */ + g2_B10, /**< B10 91 x 127 */ + g2_Comm_10_Envelope, /**< Comm #10 Envelope 297 x 684 */ + g2_C5_Envelope, /**< C5 Envelope 461 x 648 */ + g2_DL_Envelope, /**< DL Envelope 312 x 624 */ + g2_Folio, /**< Folio 595 x 935 */ + g2_Executive, /**< Executive 522 x 756 */ + g2_Letter, /**< Letter 612 x 792 */ + g2_Legal, /**< Legal 612 x 1008 */ + g2_Ledger, /**< Ledger 1224 x 792 */ + g2_Tabloid /**< Tabloid 792 x 1224 */ +}; + + +/** + * g2 paper orientation. + * + * \ingroup PS + */ +enum g2_PS_orientation { + g2_PS_land, /**< landscape */ + g2_PS_port /**< portrait */ +}; + +/* + * g2 Format + */ +enum g2_PS_format { + g2_PS_PostScript, /* PostScript */ + g2_PS_EPSF, /* EPSF format */ + g2_PS_EPSF_CLIP /* EPSF format with predefined Bounding Box*/ +}; + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + + +G2L int g2_open_PS(const char *file_name, + enum g2_PS_paper paper, + enum g2_PS_orientation orientation); + +G2L int g2_open_EPSF(const char *file_name); + +G2L int g2_open_EPSF_CLIP(const char *file_name, + long width, long height); + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_PS_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/install-sh b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/install-sh new file mode 100755 index 00000000..58719246 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/install-sh @@ -0,0 +1,238 @@ +#! /bin/sh +# +# install - install a program, script, or datafile +# This comes from X11R5. +# +# Calling this script install-sh is preferred over install.sh, to prevent +# `make' implicit rules from creating a file called install from it +# when there is no Makefile. +# +# This script is compatible with the BSD install script, but was written +# from scratch. +# + + +# set DOITPROG to echo to test this script + +# Don't use :- since 4.3BSD and earlier shells don't like it. +doit="${DOITPROG-}" + + +# put in absolute paths if you don't have them in your path; or use env. vars. + +mvprog="${MVPROG-mv}" +cpprog="${CPPROG-cp}" +chmodprog="${CHMODPROG-chmod}" +chownprog="${CHOWNPROG-chown}" +chgrpprog="${CHGRPPROG-chgrp}" +stripprog="${STRIPPROG-strip}" +rmprog="${RMPROG-rm}" +mkdirprog="${MKDIRPROG-mkdir}" + +transformbasename="" +transform_arg="" +instcmd="$mvprog" +chmodcmd="$chmodprog 0755" +chowncmd="" +chgrpcmd="" +stripcmd="" +rmcmd="$rmprog -f" +mvcmd="$mvprog" +src="" +dst="" +dir_arg="" + +while [ x"$1" != x ]; do + case $1 in + -c) instcmd="$cpprog" + shift + continue;; + + -d) dir_arg=true + shift + continue;; + + -m) chmodcmd="$chmodprog $2" + shift + shift + continue;; + + -o) chowncmd="$chownprog $2" + shift + shift + continue;; + + -g) chgrpcmd="$chgrpprog $2" + shift + shift + continue;; + + -s) stripcmd="$stripprog" + shift + continue;; + + -t=*) transformarg=`echo $1 | sed 's/-t=//'` + shift + continue;; + + -b=*) transformbasename=`echo $1 | sed 's/-b=//'` + shift + continue;; + + *) if [ x"$src" = x ] + then + src=$1 + else + # this colon is to work around a 386BSD /bin/sh bug + : + dst=$1 + fi + shift + continue;; + esac +done + +if [ x"$src" = x ] +then + echo "install: no input file specified" + exit 1 +else + true +fi + +if [ x"$dir_arg" != x ]; then + dst=$src + src="" + + if [ -d $dst ]; then + instcmd=: + else + instcmd=mkdir + fi +else + +# Waiting for this to be detected by the "$instcmd $src $dsttmp" command +# might cause directories to be created, which would be especially bad +# if $src (and thus $dsttmp) contains '*'. + + if [ -f $src -o -d $src ] + then + true + else + echo "install: $src does not exist" + exit 1 + fi + + if [ x"$dst" = x ] + then + echo "install: no destination specified" + exit 1 + else + true + fi + +# If destination is a directory, append the input filename; if your system +# does not like double slashes in filenames, you may need to add some logic + + if [ -d $dst ] + then + dst="$dst"/`basename $src` + else + true + fi +fi + +## this sed command emulates the dirname command +dstdir=`echo $dst | sed -e 's,[^/]*$,,;s,/$,,;s,^$,.,'` + +# Make sure that the destination directory exists. +# this part is taken from Noah Friedman's mkinstalldirs script + +# Skip lots of stat calls in the usual case. +if [ ! -d "$dstdir" ]; then +defaultIFS=' +' +IFS="${IFS-${defaultIFS}}" + +oIFS="${IFS}" +# Some sh's can't handle IFS=/ for some reason. +IFS='%' +set - `echo ${dstdir} | sed -e 's@/@%@g' -e 's@^%@/@'` +IFS="${oIFS}" + +pathcomp='' + +while [ $# -ne 0 ] ; do + pathcomp="${pathcomp}${1}" + shift + + if [ ! -d "${pathcomp}" ] ; + then + $mkdirprog "${pathcomp}" + else + true + fi + + pathcomp="${pathcomp}/" +done +fi + +if [ x"$dir_arg" != x ] +then + $doit $instcmd $dst && + + if [ x"$chowncmd" != x ]; then $doit $chowncmd $dst; else true ; fi && + if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd $dst; else true ; fi && + if [ x"$stripcmd" != x ]; then $doit $stripcmd $dst; else true ; fi && + if [ x"$chmodcmd" != x ]; then $doit $chmodcmd $dst; else true ; fi +else + +# If we're going to rename the final executable, determine the name now. + + if [ x"$transformarg" = x ] + then + dstfile=`basename $dst` + else + dstfile=`basename $dst $transformbasename | + sed $transformarg`$transformbasename + fi + +# don't allow the sed command to completely eliminate the filename + + if [ x"$dstfile" = x ] + then + dstfile=`basename $dst` + else + true + fi + +# Make a temp file name in the proper directory. + + dsttmp=$dstdir/#inst.$$# + +# Move or copy the file name to the temp name + + $doit $instcmd $src $dsttmp && + + trap "rm -f ${dsttmp}" 0 && + +# and set any options; do chmod last to preserve setuid bits + +# If any of these fail, we abort the whole thing. If we want to +# ignore errors from any of these, just make sure not to ignore +# errors from the above "$doit $instcmd $src $dsttmp" command. + + if [ x"$chowncmd" != x ]; then $doit $chowncmd $dsttmp; else true;fi && + if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd $dsttmp; else true;fi && + if [ x"$stripcmd" != x ]; then $doit $stripcmd $dsttmp; else true;fi && + if [ x"$chmodcmd" != x ]; then $doit $chmodcmd $dsttmp; else true;fi && + +# Now rename the file to the real destination. + + $doit $rmcmd -f $dstdir/$dstfile && + $doit $mvcmd $dsttmp $dstdir/$dstfile + +fi && + + +exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/libg2.a b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/libg2.a new file mode 100755 index 0000000000000000000000000000000000000000..788bbdddab114ce3d44af268ec5f6b9a9577f2a4 GIT binary patch literal 209838 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/CVS/Repository new file mode 100755 index 00000000..b54d25ad --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/perl/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Entries new file mode 100755 index 00000000..4cb30fa7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Entries @@ -0,0 +1,5 @@ +D/CVS//// +/Makefile.PL/1.1/Sun Aug 11 03:10:43 2002// +/README.perl/1.1/Tue Sep 3 03:11:00 2002// +/g2.pm/1.1/Wed Feb 27 02:04:40 2002// +/g2_wrap.c/1.1/Thu Aug 4 13:08:39 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Repository new file mode 100755 index 00000000..58d7bedc --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/perl diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/Makefile.PL b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/Makefile.PL new file mode 100755 index 00000000..f2cdeb28 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/Makefile.PL @@ -0,0 +1,58 @@ +use ExtUtils::MakeMaker qw(prompt WriteMakefile); + +# =====> PATHS: CHECK AND ADJUST <===== +my @INC = qw(-I../src -I../src/win32 -I../src/PS -I../src/GD); +my @LIBPATH = qw(-L../Debug -L../../gd-1.8.4); +my @LIBS = qw(-lg2); + +# FEATURE FLAGS +warn "\nPlease choose the features that match how g2 was built:\n"; + +my $PS = lc prompt('Build PostScript support?','y') eq 'y'; +my $GD = lc prompt('Build gd (Bitmap) support?','y') eq 'y'; +my $WIN32 = lc prompt('Build Win32 support?','y') eq 'y'; +my $X11 = lc prompt('Build X11 support?','y') eq 'y'; + +warn "\nIf you experience compile problems, please check the \@INC, \@LIBPATH and \@LIBS\n", + "arrays defined in Makefile.PL and manually adjust, if necessary.\n\n"; + +#### no user-serviceable parts below ##### + +push @LIBS,'-lgd' if $GD; +push @LIBS, '-lm' unless $^O eq 'MSWin32'; + +# FreeBSD 3.3 with libgd built from ports croaks if -lXpm is specified +if ($^O ne 'freebsd' && $^O ne 'MSWin32') { + push @LIBS,'-lX11','-lXpm' if $XPM; +} + +my $CAPI = defined $ExtUtils::MakeMaker::CAPI_support ? 'TRUE' : 'FALSE'; +my $DEFINES = ''; +$DEFINES .= ' -DDO_PS' if $PS; +$DEFINES .= ' -DDO_GD' if $GD; +$DEFINES .= ' -DDO_WIN32' if $WIN32; +$DEFINES .= ' -DDO_X11' if $X11; + +WriteMakefile( + 'NAME' => 'g2', + 'VERSION_FROM' => 'g2.pm', + 'dist' => {'COMPRESS'=>'gzip -9f', 'SUFFIX' => 'gz', + 'ZIP'=>'/usr/bin/zip','ZIPFLAGS'=>'-rl'}, + 'OBJECT' => 'g2_wrap.o', + 'OPTIMIZE' => '-g', + 'LIBS' => [join(' ',$ENV{'G2_LIBS'},@LIBPATH,@LIBS)], + 'INC' => join(' ',$ENV{'G2_INC'},@INC), + 'AUTHOR' => 'Horst Wagner', + 'ABSTRACT' => 'Perl interface to g2 Graphics Library', + 'CAPI' => $CAPI, + 'DEFINE' => $DEFINES, +); + +sub MY::postamble { + my $postamble = <<'END'; +html: g2.pm + pod2html --outfile=g2.html g2.pm +END + $postamble; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/README.perl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/README.perl new file mode 100755 index 00000000..049a36ea --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/README.perl @@ -0,0 +1,18 @@ +Howto build perl library + +perl Makefile.PL +swig -perl5 -o g2_wrap.c -I../src -DDO_PS -DDO_GD ../src/g2.h +"c:\Program Files\SWIG-1.3.13\swig" -perl5 -o g2_wrap.c -I../src -DDO_PS -DDO_GD -DDO_WIN32 ../src/g2.h +nmake +nmake install + +To make ActiveState PPD: + +tar cvf g2.tar blib +gzip --best g2.tar +nmake ppd +copy tar.gz file into subdir x86 +You have to edit the resulting PPD file and add the location of the package archive into . The location is relative to the PPD file. +To install do: +ppm install g2.ppd + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2.pm b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2.pm new file mode 100755 index 00000000..f58269c6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2.pm @@ -0,0 +1,10 @@ +# This file was automatically generated by SWIG +package g2; +require Exporter; +require DynaLoader; +@ISA = qw(Exporter DynaLoader); +package g2; +bootstrap g2; +package g2; +@EXPORT = qw( ); +1; diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2_wrap.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2_wrap.c new file mode 100755 index 00000000..67cdff36 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/perl/g2_wrap.c @@ -0,0 +1,2172 @@ +/* ---------------------------------------------------------------------------- + * This file was automatically generated by SWIG (http://www.swig.org). + * Version 1.3.13u-20020617-2210 + * + * This file is not intended to be easily readable and contains a number of + * coding conventions designed to improve portability and efficiency. Do not make + * changes to this file unless you know what you are doing--modify the SWIG + * interface file instead. + * ----------------------------------------------------------------------------- */ + +/*********************************************************************** + * common.swg + * + * This file contains generic SWIG runtime support for pointer + * type checking as well as a few commonly used macros to control + * external linkage. + * + * Author : David Beazley (beazley@cs.uchicago.edu) + * + * Copyright (c) 1999-2000, The University of Chicago + * + * This file may be freely redistributed without license or fee provided + * this copyright message remains intact. + ************************************************************************/ + +#include + +#if defined(_WIN32) || defined(__WIN32__) +# if defined(_MSC_VER) +# if defined(STATIC_LINKED) +# define SWIGEXPORT(a) a +# define SWIGIMPORT(a) extern a +# else +# define SWIGEXPORT(a) __declspec(dllexport) a +# define SWIGIMPORT(a) extern a +# endif +# else +# if defined(__BORLANDC__) +# define SWIGEXPORT(a) a _export +# define SWIGIMPORT(a) a _export +# else +# define SWIGEXPORT(a) a +# define SWIGIMPORT(a) a +# endif +# endif +#else +# define SWIGEXPORT(a) a +# define SWIGIMPORT(a) a +#endif + +#ifdef SWIG_GLOBAL +#define SWIGRUNTIME(a) SWIGEXPORT(a) +#else +#define SWIGRUNTIME(a) static a +#endif + +#ifdef __cplusplus +extern "C" { +#endif + +typedef void *(*swig_converter_func)(void *); +typedef struct swig_type_info *(*swig_dycast_func)(void **); + +typedef struct swig_type_info { + const char *name; + swig_converter_func converter; + const char *str; + swig_dycast_func dcast; + struct swig_type_info *next; + struct swig_type_info *prev; + void *clientdata; +} swig_type_info; + +#ifdef SWIG_NOINCLUDE + +SWIGIMPORT(swig_type_info *) SWIG_TypeRegister(swig_type_info *); +SWIGIMPORT(swig_type_info *) SWIG_TypeCheck(char *c, swig_type_info *); +SWIGIMPORT(void *) SWIG_TypeCast(swig_type_info *, void *); +SWIGIMPORT(swig_type_info *) SWIG_TypeDynamicCast(swig_type_info *, void **); +SWIGIMPORT(swig_type_info *) SWIG_TypeQuery(const char *); +SWIGIMPORT(void) SWIG_TypeClientData(swig_type_info *, void *); + +#else + +static swig_type_info *swig_type_list = 0; + +/* Register a type mapping with the type-checking */ +SWIGRUNTIME(swig_type_info *) +SWIG_TypeRegister(swig_type_info *ti) +{ + swig_type_info *tc, *head, *ret, *next; + /* Check to see if this type has already been registered */ + tc = swig_type_list; + while (tc) { + if (strcmp(tc->name, ti->name) == 0) { + /* Already exists in the table. Just add additional types to the list */ + head = tc; + next = tc->next; + goto l1; + } + tc = tc->prev; + } + head = ti; + next = 0; + + /* Place in list */ + ti->prev = swig_type_list; + swig_type_list = ti; + + /* Build linked lists */ + l1: + ret = head; + tc = ti + 1; + /* Patch up the rest of the links */ + while (tc->name) { + head->next = tc; + tc->prev = head; + head = tc; + tc++; + } + head->next = next; + return ret; +} + +/* Check the typename */ +SWIGRUNTIME(swig_type_info *) +SWIG_TypeCheck(char *c, swig_type_info *ty) +{ + swig_type_info *s; + if (!ty) return 0; /* Void pointer */ + s = ty->next; /* First element always just a name */ + while (s) { + if (strcmp(s->name,c) == 0) { + if (s == ty->next) return s; + /* Move s to the top of the linked list */ + s->prev->next = s->next; + if (s->next) { + s->next->prev = s->prev; + } + /* Insert s as second element in the list */ + s->next = ty->next; + if (ty->next) ty->next->prev = s; + ty->next = s; + return s; + } + s = s->next; + } + return 0; +} + +/* Cast a pointer up an inheritance hierarchy */ +SWIGRUNTIME(void *) +SWIG_TypeCast(swig_type_info *ty, void *ptr) +{ + if ((!ty) || (!ty->converter)) return ptr; + return (*ty->converter)(ptr); +} + +/* Dynamic pointer casting. Down an inheritance hierarchy */ +SWIGRUNTIME(swig_type_info *) +SWIG_TypeDynamicCast(swig_type_info *ty, void **ptr) +{ + swig_type_info *lastty = ty; + if (!ty || !ty->dcast) return ty; + while (ty && (ty->dcast)) { + ty = (*ty->dcast)(ptr); + if (ty) lastty = ty; + } + return lastty; +} + +/* Search for a swig_type_info structure */ +SWIGRUNTIME(swig_type_info *) +SWIG_TypeQuery(const char *name) { + swig_type_info *ty = swig_type_list; + while (ty) { + if (ty->str && (strcmp(name,ty->str) == 0)) return ty; + if (ty->name && (strcmp(name,ty->name) == 0)) return ty; + ty = ty->prev; + } + return 0; +} + +/* Set the clientdata field for a type */ +SWIGRUNTIME(void) +SWIG_TypeClientData(swig_type_info *ti, void *clientdata) { + swig_type_info *tc, *equiv; + if (ti->clientdata) return; + ti->clientdata = clientdata; + equiv = ti->next; + while (equiv) { + if (!equiv->converter) { + tc = swig_type_list; + while (tc) { + if ((strcmp(tc->name, equiv->name) == 0)) + SWIG_TypeClientData(tc,clientdata); + tc = tc->prev; + } + } + equiv = equiv->next; + } +} +#endif + +#ifdef __cplusplus +} + +#endif + +/* ----------------------------------------------------------------------------- + * perl5.swg + * + * Perl5 runtime library + * $Header: /homes/mhoechsm/cvsroot/RNAforester/g2-0.70/perl/g2_wrap.c,v 1.1 2005/08/04 13:08:39 mhoechsm Exp $ + * ----------------------------------------------------------------------------- */ + +#define SWIGPERL +#define SWIGPERL5 +#ifdef __cplusplus +/* Needed on some windows machines---since MS plays funny + games with the header files under C++ */ +#include +#include +extern "C" { +#endif +#include "EXTERN.h" +#include "perl.h" +#include "XSUB.h" + +/* Get rid of free and malloc defined by perl */ +#undef free +#undef malloc + +#ifndef pTHX_ +#define pTHX_ +#endif + +#include +#ifdef __cplusplus +} +#endif + +/* Note: SwigMagicFuncHack is a typedef used to get the C++ + compiler to just shut up already */ + +#ifdef PERL_OBJECT +#define MAGIC_PPERL CPerlObj *pPerl = (CPerlObj *) this; +typedef int (CPerlObj::*SwigMagicFunc)(SV *, MAGIC *); + +#ifdef __cplusplus +extern "C" { +#endif +typedef int (CPerlObj::*SwigMagicFuncHack)(SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + +#define SWIG_MAGIC(a,b) (SV *a, MAGIC *b) +#define SWIGCLASS_STATIC +#else +#define MAGIC_PPERL +#define SWIGCLASS_STATIC static +#ifndef MULTIPLICITY +#define SWIG_MAGIC(a,b) (SV *a, MAGIC *b) +typedef int (*SwigMagicFunc)(SV *, MAGIC *); + +#ifdef __cplusplus +extern "C" { +#endif +typedef int (*SwigMagicFuncHack)(SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + + +#else +#define SWIG_MAGIC(a,b) (struct interpreter *interp, SV *a, MAGIC *b) +typedef int (*SwigMagicFunc)(struct interpreter *, SV *, MAGIC *); +#ifdef __cplusplus +extern "C" { +#endif +typedef int (*SwigMagicFuncHack)(struct interpreter *, SV *, MAGIC *); +#ifdef __cplusplus +} +#endif + +#endif +#endif + +#if defined(WIN32) && defined(PERL_OBJECT) && !defined(PerlIO_exportFILE) +#define PerlIO_exportFILE(fh,fl) (FILE*)(fh) +#endif + +/* Modifications for newer Perl 5.005 releases */ + +#if !defined(PERL_REVISION) || ((PERL_REVISION >= 5) && ((PERL_VERSION < 5) || ((PERL_VERSION == 5) && (PERL_SUBVERSION < 50)))) +#ifndef PL_sv_yes +#define PL_sv_yes sv_yes +#endif +#ifndef PL_sv_undef +#define PL_sv_undef sv_undef +#endif +#ifndef PL_na +#define PL_na na +#endif +#endif + +#include + +#ifdef __cplusplus +extern "C" { +#endif + +#ifdef SWIG_NOINCLUDE + +#ifndef PERL_OBJECT +extern int SWIG_ConvertPtr(SV *, void **, swig_type_info *, int flags); +extern void SWIG_MakePtr(SV *, void *, swig_type_info *, int flags); +#else +extern int _SWIG_ConvertPtr(CPerlObj *, SV *, void **, swig_type_info *,int flags); +extern void _SWIG_MakePtr(CPerlObj *, SV *, void *, swig_type_info *, int flags); +#define SWIG_ConvertPtr(a,b,c,d) _SWIG_ConvertPtr(pPerl,a,b,c,d) +#define SWIG_MakePtr(a,b,c,d) _SWIG_MakePtr(pPerl,a,b,c,d) +#endif + +#else + +/* Function for getting a pointer value */ + +#ifndef PERL_OBJECT +SWIGRUNTIME(int) +SWIG_ConvertPtr(SV *sv, void **ptr, swig_type_info *_t, int flags) +#else +#define SWIG_ConvertPtr(a,b,c,d) _SWIG_ConvertPtr(pPerl,a,b,c,d) +SWIGRUNTIME(int) +_SWIG_ConvertPtr(CPerlObj *pPerl, SV *sv, void **ptr, swig_type_info *_t, int flags) +#endif +{ + char *_c; + swig_type_info *tc; + IV tmp; + + /* If magical, apply more magic */ + if (SvGMAGICAL(sv)) + mg_get(sv); + + /* Check to see if this is an object */ + if (sv_isobject(sv)) { + SV *tsv = (SV*) SvRV(sv); + if ((SvTYPE(tsv) == SVt_PVHV)) { + MAGIC *mg; + if (SvMAGICAL(tsv)) { + mg = mg_find(tsv,'P'); + if (mg) { + SV *rsv = mg->mg_obj; + if (sv_isobject(rsv)) { + tmp = SvIV((SV*)SvRV(rsv)); + } + } + } else { + return -1; + } + } else { + tmp = SvIV((SV*)SvRV(sv)); + } + if (!_t) { + *(ptr) = (void *) tmp; + return 0; + } + } else if (! SvOK(sv)) { /* Check for undef */ + *(ptr) = (void *) 0; + return 0; + } else if (SvTYPE(sv) == SVt_RV) { /* Check for NULL pointer */ + *(ptr) = (void *) 0; + if (!SvROK(sv)) + return 0; + else + return -1; + } else { /* Don't know what it is */ + *(ptr) = (void *) 0; + return -1; + } + if (_t) { + /* Now see if the types match */ + _c = HvNAME(SvSTASH(SvRV(sv))); + tc = SWIG_TypeCheck(_c,_t); + if (!tc) { + *ptr = (void *) tmp; + return -1; + } + *ptr = SWIG_TypeCast(tc,(void *)tmp); + return 0; + } + *ptr = (void *) tmp; + return 0; +} +#ifndef PERL_OBJECT +SWIGRUNTIME(void) +SWIG_MakePtr(SV *sv, void *ptr, swig_type_info *t,int flags) +#else +#define SWIG_MakePtr(a,b,c,d) _SWIG_MakePtr(pPerl,a,b,c,d) +SWIGRUNTIME(void) +_SWIG_MakePtr(CPerlObj *pPerl, SV *sv, void *ptr, swig_type_info *t, int flags) +#endif +{ + sv_setref_pv(sv, (char *) t->name, ptr); +} + +#endif + +typedef XS(SwigPerlWrapper); +typedef SwigPerlWrapper *SwigPerlWrapperPtr; + +/* Structure for command table */ +typedef struct { + const char *name; + SwigPerlWrapperPtr wrapper; +} swig_command_info; + +/* Information for constant table */ + +#define SWIG_INT 1 +#define SWIG_FLOAT 2 +#define SWIG_STRING 3 +#define SWIG_POINTER 4 +#define SWIG_BINARY 5 + +/* Constant information structure */ +typedef struct swig_constant_info { + int type; + const char *name; + long lvalue; + double dvalue; + void *pvalue; + swig_type_info **ptype; +} swig_constant_info; + +#ifdef __cplusplus +} +#endif + +/* Structure for variable table */ +typedef struct { + const char *name; + SwigMagicFunc set; + SwigMagicFunc get; + swig_type_info **type; +} swig_variable_info; + +/* Magic variable code */ +#ifndef PERL_OBJECT +#define swig_create_magic(s,a,b,c) _swig_create_magic(s,a,b,c) + #ifndef MULTIPLICITY + static void _swig_create_magic(SV *sv, char *name, int (*set)(SV *, MAGIC *), int \ +(*get)(SV *,MAGIC *)) { + #else + static void _swig_create_magic(SV *sv, char *name, int (*set)(struct interpreter*,\ + SV *, MAGIC *), int (*get)(struct interpreter*, SV *,MAGIC *)) { + #endif +#else +#define swig_create_magic(s,a,b,c) _swig_create_magic(pPerl,s,a,b,c) +static void _swig_create_magic(CPerlObj *pPerl, SV *sv, const char *name, int (CPerlObj::*set)(SV *, MAGIC *), int (CPerlObj::*get)(SV *, MAGIC *)) { +#endif + MAGIC *mg; + sv_magic(sv,sv,'U',(char *) name,strlen(name)); + mg = mg_find(sv,'U'); + mg->mg_virtual = (MGVTBL *) malloc(sizeof(MGVTBL)); + mg->mg_virtual->svt_get = (SwigMagicFuncHack) get; + mg->mg_virtual->svt_set = (SwigMagicFuncHack) set; + mg->mg_virtual->svt_len = 0; + mg->mg_virtual->svt_clear = 0; + mg->mg_virtual->svt_free = 0; +} + + + + + + + +/* -------- TYPES TABLE (BEGIN) -------- */ + +#define SWIGTYPE_p_double swig_types[0] +#define SWIGTYPE_p_int swig_types[1] +static swig_type_info *swig_types[3]; + +/* -------- TYPES TABLE (END) -------- */ + +#define SWIG_init boot_g2 + +#define SWIG_name "g2::boot_g2" +#define SWIG_prefix "g2::" + +#ifdef __cplusplus +extern "C" +#endif +#ifndef PERL_OBJECT +#ifndef MULTIPLICITY +SWIGEXPORT(void) SWIG_init (CV* cv); +#else +SWIGEXPORT(void) SWIG_init (pTHXo_ CV* cv); +#endif +#else +SWIGEXPORT(void) SWIG_init (CV *cv, CPerlObj *); +#endif + + +#include "g2.h" +#if defined(DO_X11) +#include "g2_X11.h" +#endif +#if defined(DO_PS) +#include "g2_PS.h" +#endif +#if defined(DO_GD) +#include "g2_gd.h" +#endif +#if defined(DO_WIN32) +#include "WIN32/g2_win32.h" +#endif + +extern void g2_query_pointer(int,double *,double *,unsigned int *); +#ifdef PERL_OBJECT +#define MAGIC_CLASS _wrap_g2_var:: +class _wrap_g2_var : public CPerlObj { +public: +#else +#define MAGIC_CLASS +#endif +SWIGCLASS_STATIC int swig_magic_readonly(pTHX_ SV *sv, MAGIC *mg) { + MAGIC_PPERL + sv = sv; mg = mg; + croak("Value is read-only."); + return 0; +} + + +#ifdef PERL_OBJECT +}; +#endif + +#ifdef __cplusplus +extern "C" { +#endif +XS(_wrap_g2_open_PS) { + char *arg1 ; + int arg2 ; + int arg3 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_open_PS(file_name,paper,orientation);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + arg2 = (int) SvIV(ST(1)); + arg3 = (int) SvIV(ST(2)); + result = (int)g2_open_PS((char const *)arg1,(enum g2_PS_paper)arg2,(enum g2_PS_orientation)arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_open_EPSF) { + char *arg1 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_open_EPSF(file_name);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + result = (int)g2_open_EPSF((char const *)arg1); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_open_EPSF_CLIP) { + char *arg1 ; + long arg2 ; + long arg3 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_open_EPSF_CLIP(file_name,width,height);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + arg2 = (long) SvIV(ST(1)); + arg3 = (long) SvIV(ST(2)); + result = (int)g2_open_EPSF_CLIP((char const *)arg1,arg2,arg3); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_open_gd) { + char *arg1 ; + int arg2 ; + int arg3 ; + int arg4 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_open_gd(filename,width,height,gd_type);"); + } + if (!SvOK((SV*) ST(0))) arg1 = 0; + else arg1 = (char *) SvPV(ST(0), PL_na); + arg2 = (int) SvIV(ST(1)); + arg3 = (int) SvIV(ST(2)); + arg4 = (int) SvIV(ST(3)); + result = (int)g2_open_gd((char const *)arg1,arg2,arg3,(enum g2_gd_type)arg4); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_open_win32) { + int arg1 ; + int arg2 ; + char *arg3 ; + int arg4 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_open_win32(width,height,filename,type);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + if (!SvOK((SV*) ST(2))) arg3 = 0; + else arg3 = (char *) SvPV(ST(2), PL_na); + arg4 = (int) SvIV(ST(3)); + result = (int)g2_open_win32(arg1,arg2,(char const *)arg3,arg4); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_open_vd) { + int result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + croak("Usage: g2_open_vd();"); + } + result = (int)g2_open_vd(); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_attach) { + int arg1 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_attach(vd_dev,dev);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + g2_attach(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_detach) { + int arg1 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_detach(vd_dev,dev);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + g2_detach(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_close) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_close(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_close(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_auto_flush) { + int arg1 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_set_auto_flush(dev,on_off);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + g2_set_auto_flush(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_flush) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_flush(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_flush(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_save) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_save(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_save(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_coordinate_system) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_set_coordinate_system(dev,x_origin,y_origin,x_mul,y_mul);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_set_coordinate_system(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_ld) { + int result; + int argvi = 0; + dXSARGS; + + if ((items < 0) || (items > 0)) { + croak("Usage: g2_ld();"); + } + result = (int)g2_ld(); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_ld) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_set_ld(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_set_ld(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_ink) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_ink(pd_dev,red,green,blue);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + result = (int)g2_ink(arg1,arg2,arg3,arg4); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + +XS(_wrap_g2_pen) { + int arg1 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_pen(dev,color);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + g2_pen(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_dash) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_set_dash(dev,N,dashes);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_set_dash. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_set_dash(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_font_size) { + int arg1 ; + double arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_set_font_size(dev,size);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + g2_set_font_size(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_line_width) { + int arg1 ; + double arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_set_line_width(dev,w);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + g2_set_line_width(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_clear_palette) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_clear_palette(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_clear_palette(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_reset_palette) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_reset_palette(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_reset_palette(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_allocate_basic_colors) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_allocate_basic_colors(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_allocate_basic_colors(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_clear) { + int arg1 ; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_clear(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_clear(arg1); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_background) { + int arg1 ; + int arg2 ; + int argvi = 0; + dXSARGS; + + if ((items < 2) || (items > 2)) { + croak("Usage: g2_set_background(dev,color);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + g2_set_background(arg1,arg2); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_move) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_move(dev,x,y);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_move(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_move_r) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_move_r(dev,dx,dy);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_move_r(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_plot) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_plot(dev,x,y);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_plot(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_plot_r) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_plot_r(dev,dx,dy);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_plot_r(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_line) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_line(dev,x1,y1,x2,y2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_line(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_line_r) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_line_r(dev,dx,dy);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_line_r(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_line_to) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_line_to(dev,x,y);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_line_to(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_poly_line) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_poly_line(dev,N_pt,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_poly_line. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_poly_line(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_triangle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + double arg6 ; + double arg7 ; + int argvi = 0; + dXSARGS; + + if ((items < 7) || (items > 7)) { + croak("Usage: g2_triangle(dev,x1,y1,x2,y2,x3,y3);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + arg6 = (double) SvNV(ST(5)); + + arg7 = (double) SvNV(ST(6)); + + g2_triangle(arg1,arg2,arg3,arg4,arg5,arg6,arg7); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_triangle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + double arg6 ; + double arg7 ; + int argvi = 0; + dXSARGS; + + if ((items < 7) || (items > 7)) { + croak("Usage: g2_filled_triangle(dev,x1,y1,x2,y2,x3,y3);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + arg6 = (double) SvNV(ST(5)); + + arg7 = (double) SvNV(ST(6)); + + g2_filled_triangle(arg1,arg2,arg3,arg4,arg5,arg6,arg7); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_rectangle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_rectangle(dev,x1,y1,x2,y2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_rectangle(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_rectangle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_filled_rectangle(dev,x1,y1,x2,y2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_filled_rectangle(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_polygon) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_polygon(dev,N_pt,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_polygon. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_polygon(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_polygon) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_filled_polygon(dev,N_pt,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_polygon. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_filled_polygon(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_circle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_circle(dev,x,y,r);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + g2_circle(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_circle) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_filled_circle(dev,x,y,r);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + g2_filled_circle(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_ellipse) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_ellipse(dev,x,y,r1,r2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_ellipse(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_ellipse) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + int argvi = 0; + dXSARGS; + + if ((items < 5) || (items > 5)) { + croak("Usage: g2_filled_ellipse(dev,x,y,r1,r2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + g2_filled_ellipse(arg1,arg2,arg3,arg4,arg5); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_arc) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + double arg6 ; + double arg7 ; + int argvi = 0; + dXSARGS; + + if ((items < 7) || (items > 7)) { + croak("Usage: g2_arc(dev,x,y,r1,r2,a1,a2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + arg6 = (double) SvNV(ST(5)); + + arg7 = (double) SvNV(ST(6)); + + g2_arc(arg1,arg2,arg3,arg4,arg5,arg6,arg7); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_arc) { + int arg1 ; + double arg2 ; + double arg3 ; + double arg4 ; + double arg5 ; + double arg6 ; + double arg7 ; + int argvi = 0; + dXSARGS; + + if ((items < 7) || (items > 7)) { + croak("Usage: g2_filled_arc(dev,x,y,r1,r2,a1,a2);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (double) SvNV(ST(3)); + + arg5 = (double) SvNV(ST(4)); + + arg6 = (double) SvNV(ST(5)); + + arg7 = (double) SvNV(ST(6)); + + g2_filled_arc(arg1,arg2,arg3,arg4,arg5,arg6,arg7); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_string) { + int arg1 ; + double arg2 ; + double arg3 ; + char *arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_string(dev,x,y,text);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + if (!SvOK((SV*) ST(3))) arg4 = 0; + else arg4 = (char *) SvPV(ST(3), PL_na); + g2_string(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_image) { + int arg1 ; + double arg2 ; + double arg3 ; + int arg4 ; + int arg5 ; + int *arg6 ; + int argvi = 0; + dXSARGS; + + if ((items < 6) || (items > 6)) { + croak("Usage: g2_image(dev,x,y,x_size,y_size,pens);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + arg4 = (int) SvIV(ST(3)); + arg5 = (int) SvIV(ST(4)); + { + if (SWIG_ConvertPtr(ST(5), (void **) &arg6, SWIGTYPE_p_int,0) < 0) { + croak("Type error in argument 6 of g2_image. Expected %s", SWIGTYPE_p_int->name); + } + } + g2_image(arg1,arg2,arg3,arg4,arg5,arg6); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_set_QP) { + int arg1 ; + double arg2 ; + int arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_set_QP(dev,d,shape);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (int) SvIV(ST(2)); + g2_set_QP(arg1,arg2,(enum QPshape)arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_plot_QP) { + int arg1 ; + double arg2 ; + double arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_plot_QP(dev,x,y);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (double) SvNV(ST(1)); + + arg3 = (double) SvNV(ST(2)); + + g2_plot_QP(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_query_pointer) { + int arg1 ; + double *arg2 ; + double *arg3 ; + unsigned int *arg4 ; + double temp2 ; + double temp3 ; + unsigned int temp4 ; + int argvi = 0; + dXSARGS; + + { + arg2 = &temp2; + } + { + arg3 = &temp3; + } + { + arg4 = &temp4; + } + if ((items < 1) || (items > 1)) { + croak("Usage: g2_query_pointer(dev);"); + } + arg1 = (int) SvIV(ST(0)); + g2_query_pointer(arg1,arg2,arg3,arg4); + + + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg2)); + argvi++; + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setnv(ST(argvi),(double) *(arg3)); + argvi++; + } + { + if (argvi >= items) { + EXTEND(sp,1); + } + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi),(IV) *(arg4)); + argvi++; + } + XSRETURN(argvi); +} + + +XS(_wrap_g2_spline) { + int arg1 ; + int arg2 ; + double *arg3 ; + int arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_spline(id,n,points,o);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_spline. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (int) SvIV(ST(3)); + g2_spline(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_b_spline) { + int arg1 ; + int arg2 ; + double *arg3 ; + int arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_b_spline(id,n,points,o);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_b_spline. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (int) SvIV(ST(3)); + g2_b_spline(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_raspln) { + int arg1 ; + int arg2 ; + double *arg3 ; + double arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_raspln(id,n,points,tn);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_raspln. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (double) SvNV(ST(3)); + + g2_raspln(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_para_3) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_para_3(id,n,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_para_3. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_para_3(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_para_5) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_para_5(id,n,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_para_5. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_para_5(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_spline) { + int arg1 ; + int arg2 ; + double *arg3 ; + int arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_filled_spline(id,n,points,o);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_spline. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (int) SvIV(ST(3)); + g2_filled_spline(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_b_spline) { + int arg1 ; + int arg2 ; + double *arg3 ; + int arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_filled_b_spline(id,n,points,o);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_b_spline. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (int) SvIV(ST(3)); + g2_filled_b_spline(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_raspln) { + int arg1 ; + int arg2 ; + double *arg3 ; + double arg4 ; + int argvi = 0; + dXSARGS; + + if ((items < 4) || (items > 4)) { + croak("Usage: g2_filled_raspln(id,n,points,tn);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_raspln. Expected %s", SWIGTYPE_p_double->name); + } + } + arg4 = (double) SvNV(ST(3)); + + g2_filled_raspln(arg1,arg2,arg3,arg4); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_para_3) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_filled_para_3(id,n,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_para_3. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_filled_para_3(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_filled_para_5) { + int arg1 ; + int arg2 ; + double *arg3 ; + int argvi = 0; + dXSARGS; + + if ((items < 3) || (items > 3)) { + croak("Usage: g2_filled_para_5(id,n,points);"); + } + arg1 = (int) SvIV(ST(0)); + arg2 = (int) SvIV(ST(1)); + { + if (SWIG_ConvertPtr(ST(2), (void **) &arg3, SWIGTYPE_p_double,0) < 0) { + croak("Type error in argument 3 of g2_filled_para_5. Expected %s", SWIGTYPE_p_double->name); + } + } + g2_filled_para_5(arg1,arg2,arg3); + + + XSRETURN(argvi); +} + + +XS(_wrap_g2_device_exist) { + int arg1 ; + int result; + int argvi = 0; + dXSARGS; + + if ((items < 1) || (items > 1)) { + croak("Usage: g2_device_exist(dix);"); + } + arg1 = (int) SvIV(ST(0)); + result = (int)g2_device_exist(arg1); + + ST(argvi) = sv_newmortal(); + sv_setiv(ST(argvi++), (IV) result); + XSRETURN(argvi); +} + + + +/* -------- TYPE CONVERSION AND EQUIVALENCE RULES (BEGIN) -------- */ + +static swig_type_info _swigt__p_double[] = {{"_p_double", 0, "double *"},{"_p_double"},{0}}; +static swig_type_info _swigt__p_int[] = {{"_p_int", 0, "int *"},{"_p_int"},{0}}; + +static swig_type_info *swig_types_initial[] = { +_swigt__p_double, +_swigt__p_int, +0 +}; + + +/* -------- TYPE CONVERSION AND EQUIVALENCE RULES (END) -------- */ + +static swig_constant_info swig_constants[] = { +{ SWIG_STRING, (char *) SWIG_prefix "G2_VERSION", 0, 0, (void *)"0.41a", 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A0", (long) g2_A0, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A1", (long) g2_A1, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A2", (long) g2_A2, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A3", (long) g2_A3, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A4", (long) g2_A4, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A5", (long) g2_A5, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A6", (long) g2_A6, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A7", (long) g2_A7, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A8", (long) g2_A8, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_A9", (long) g2_A9, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B0", (long) g2_B0, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B1", (long) g2_B1, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B2", (long) g2_B2, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B3", (long) g2_B3, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B4", (long) g2_B4, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B5", (long) g2_B5, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B6", (long) g2_B6, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B7", (long) g2_B7, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B8", (long) g2_B8, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B9", (long) g2_B9, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_B10", (long) g2_B10, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Comm_10_Envelope", (long) g2_Comm_10_Envelope, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_C5_Envelope", (long) g2_C5_Envelope, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_DL_Envelope", (long) g2_DL_Envelope, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Folio", (long) g2_Folio, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Executive", (long) g2_Executive, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Letter", (long) g2_Letter, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Legal", (long) g2_Legal, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Ledger", (long) g2_Ledger, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_Tabloid", (long) g2_Tabloid, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_PS_land", (long) g2_PS_land, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_PS_port", (long) g2_PS_port, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_PS_PostScript", (long) g2_PS_PostScript, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_PS_EPSF", (long) g2_PS_EPSF, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_PS_EPSF_CLIP", (long) g2_PS_EPSF_CLIP, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_gd_jpeg", (long) g2_gd_jpeg, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_gd_png", (long) g2_gd_png, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_win32", (long) g2_win32, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "g2_wmf32", (long) g2_wmf32, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "QPrect", (long) QPrect, 0, 0, 0}, +{ SWIG_INT, (char *) SWIG_prefix "QPcirc", (long) QPcirc, 0, 0, 0}, +{0} +}; +#ifdef __cplusplus +} +#endif +static swig_variable_info swig_variables[] = { +{0} +}; +static swig_command_info swig_commands[] = { +{"g2::g2_open_PS", _wrap_g2_open_PS}, +{"g2::g2_open_EPSF", _wrap_g2_open_EPSF}, +{"g2::g2_open_EPSF_CLIP", _wrap_g2_open_EPSF_CLIP}, +{"g2::g2_open_gd", _wrap_g2_open_gd}, +{"g2::g2_open_win32", _wrap_g2_open_win32}, +{"g2::g2_open_vd", _wrap_g2_open_vd}, +{"g2::g2_attach", _wrap_g2_attach}, +{"g2::g2_detach", _wrap_g2_detach}, +{"g2::g2_close", _wrap_g2_close}, +{"g2::g2_set_auto_flush", _wrap_g2_set_auto_flush}, +{"g2::g2_flush", _wrap_g2_flush}, +{"g2::g2_save", _wrap_g2_save}, +{"g2::g2_set_coordinate_system", _wrap_g2_set_coordinate_system}, +{"g2::g2_ld", _wrap_g2_ld}, +{"g2::g2_set_ld", _wrap_g2_set_ld}, +{"g2::g2_ink", _wrap_g2_ink}, +{"g2::g2_pen", _wrap_g2_pen}, +{"g2::g2_set_dash", _wrap_g2_set_dash}, +{"g2::g2_set_font_size", _wrap_g2_set_font_size}, +{"g2::g2_set_line_width", _wrap_g2_set_line_width}, +{"g2::g2_clear_palette", _wrap_g2_clear_palette}, +{"g2::g2_reset_palette", _wrap_g2_reset_palette}, +{"g2::g2_allocate_basic_colors", _wrap_g2_allocate_basic_colors}, +{"g2::g2_clear", _wrap_g2_clear}, +{"g2::g2_set_background", _wrap_g2_set_background}, +{"g2::g2_move", _wrap_g2_move}, +{"g2::g2_move_r", _wrap_g2_move_r}, +{"g2::g2_plot", _wrap_g2_plot}, +{"g2::g2_plot_r", _wrap_g2_plot_r}, +{"g2::g2_line", _wrap_g2_line}, +{"g2::g2_line_r", _wrap_g2_line_r}, +{"g2::g2_line_to", _wrap_g2_line_to}, +{"g2::g2_poly_line", _wrap_g2_poly_line}, +{"g2::g2_triangle", _wrap_g2_triangle}, +{"g2::g2_filled_triangle", _wrap_g2_filled_triangle}, +{"g2::g2_rectangle", _wrap_g2_rectangle}, +{"g2::g2_filled_rectangle", _wrap_g2_filled_rectangle}, +{"g2::g2_polygon", _wrap_g2_polygon}, +{"g2::g2_filled_polygon", _wrap_g2_filled_polygon}, +{"g2::g2_circle", _wrap_g2_circle}, +{"g2::g2_filled_circle", _wrap_g2_filled_circle}, +{"g2::g2_ellipse", _wrap_g2_ellipse}, +{"g2::g2_filled_ellipse", _wrap_g2_filled_ellipse}, +{"g2::g2_arc", _wrap_g2_arc}, +{"g2::g2_filled_arc", _wrap_g2_filled_arc}, +{"g2::g2_string", _wrap_g2_string}, +{"g2::g2_image", _wrap_g2_image}, +{"g2::g2_set_QP", _wrap_g2_set_QP}, +{"g2::g2_plot_QP", _wrap_g2_plot_QP}, +{"g2::g2_query_pointer", _wrap_g2_query_pointer}, +{"g2::g2_spline", _wrap_g2_spline}, +{"g2::g2_b_spline", _wrap_g2_b_spline}, +{"g2::g2_raspln", _wrap_g2_raspln}, +{"g2::g2_para_3", _wrap_g2_para_3}, +{"g2::g2_para_5", _wrap_g2_para_5}, +{"g2::g2_filled_spline", _wrap_g2_filled_spline}, +{"g2::g2_filled_b_spline", _wrap_g2_filled_b_spline}, +{"g2::g2_filled_raspln", _wrap_g2_filled_raspln}, +{"g2::g2_filled_para_3", _wrap_g2_filled_para_3}, +{"g2::g2_filled_para_5", _wrap_g2_filled_para_5}, +{"g2::g2_device_exist", _wrap_g2_device_exist}, +{0,0} +}; + +#ifdef __cplusplus +extern "C" +#endif + +XS(SWIG_init) { + dXSARGS; + int i; + for (i = 0; swig_types_initial[i]; i++) { + swig_types[i] = SWIG_TypeRegister(swig_types_initial[i]); + } + + /* Install commands */ + for (i = 0; swig_commands[i].name; i++) { + newXS((char*) swig_commands[i].name,swig_commands[i].wrapper, (char*)__FILE__); + } + + /* Install variables */ + for (i = 0; swig_variables[i].name; i++) { + SV *sv; + sv = perl_get_sv((char*) swig_variables[i].name, TRUE | 0x2); + if (swig_variables[i].type) { + SWIG_MakePtr(sv,(void *)1, *swig_variables[i].type,0); + }else { + sv_setiv(sv,(IV) 0); + } + swig_create_magic(sv, (char *) swig_variables[i].name, swig_variables[i].set, swig_variables[i].get); + } + + /* Install constant */ + for (i = 0; swig_constants[i].type; i++) { + SV *sv; + sv = perl_get_sv((char*)swig_constants[i].name, TRUE | 0x2); + switch(swig_constants[i].type) { + case SWIG_INT: + sv_setiv(sv, (IV) swig_constants[i].lvalue); + break; + case SWIG_FLOAT: + sv_setnv(sv, (double) swig_constants[i].dvalue); + break; + case SWIG_STRING: + sv_setpv(sv, (char *) swig_constants[i].pvalue); + break; + case SWIG_POINTER: + SWIG_MakePtr(sv, swig_constants[i].pvalue, *(swig_constants[i].ptype),0); + break; + case SWIG_BINARY: + /* obj = SWIG_NewPackedObj(swig_constants[i].pvalue, swig_constants[i].lvalue, *(swig_constants[i].ptype)); */ + break; + default: + break; + } + SvREADONLY_on(sv); + } + + ST(0) = &PL_sv_yes; + XSRETURN(1); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/simple_win32.dsp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/simple_win32.dsp new file mode 100755 index 00000000..fae2d33c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/simple_win32.dsp @@ -0,0 +1,101 @@ +# Microsoft Developer Studio Project File - Name="simple_win32" - Package Owner=<4> +# Microsoft Developer Studio Generated Build File, Format Version 6.00 +# ** DO NOT EDIT ** + +# TARGTYPE "Win32 (x86) Console Application" 0x0103 + +CFG=simple_win32 - Win32 Debug +!MESSAGE This is not a valid makefile. To build this project using NMAKE, +!MESSAGE use the Export Makefile command and run +!MESSAGE +!MESSAGE NMAKE /f "simple_win32.mak". +!MESSAGE +!MESSAGE You can specify a configuration when running NMAKE +!MESSAGE by defining the macro CFG on the command line. For example: +!MESSAGE +!MESSAGE NMAKE /f "simple_win32.mak" CFG="simple_win32 - Win32 Debug" +!MESSAGE +!MESSAGE Possible choices for configuration are: +!MESSAGE +!MESSAGE "simple_win32 - Win32 Release" (based on "Win32 (x86) Console Application") +!MESSAGE "simple_win32 - Win32 Debug" (based on "Win32 (x86) Console Application") +!MESSAGE + +# Begin Project +# PROP AllowPerConfigDependencies 0 +# PROP Scc_ProjName "" +# PROP Scc_LocalPath "" +CPP=cl.exe +RSC=rc.exe + +!IF "$(CFG)" == "simple_win32 - Win32 Release" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 0 +# PROP BASE Output_Dir "Release" +# PROP BASE Intermediate_Dir "Release" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 0 +# PROP Output_Dir "Release" +# PROP Intermediate_Dir "Release" +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD CPP /nologo /W3 /GX /O2 /I "src/gd" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /D "WIN32" /D "NDEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /c +# ADD BASE RSC /l 0x409 /d "NDEBUG" +# ADD RSC /l 0x409 /d "NDEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /machine:I386 + +!ELSEIF "$(CFG)" == "simple_win32 - Win32 Debug" + +# PROP BASE Use_MFC 0 +# PROP BASE Use_Debug_Libraries 1 +# PROP BASE Output_Dir "simple_win32___Win32_Debug" +# PROP BASE Intermediate_Dir "simple_win32___Win32_Debug" +# PROP BASE Target_Dir "" +# PROP Use_MFC 0 +# PROP Use_Debug_Libraries 1 +# PROP Output_Dir "Debug" +# PROP Intermediate_Dir "Debug" +# PROP Ignore_Export_Lib 0 +# PROP Target_Dir "" +# ADD BASE CPP /nologo /W3 /Gm /GX /ZI /Od /D "WIN32" /D "_DEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /GZ /c +# ADD CPP /nologo /W3 /Gm /GX /ZI /Od /I "src/gd" /I "./src" /I "src" /I "src/PS" /I "src/WIN32" /I "src/GD" /D "WIN32" /D "_DEBUG" /D "_CONSOLE" /D "_MBCS" /YX /FD /GZ /c +# ADD BASE RSC /l 0x409 /d "_DEBUG" +# ADD RSC /l 0x409 /d "_DEBUG" +BSC32=bscmake.exe +# ADD BASE BSC32 /nologo +# ADD BSC32 /nologo +LINK32=link.exe +# ADD BASE LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /debug /machine:I386 /pdbtype:sept +# ADD LINK32 kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib kernel32.lib user32.lib gdi32.lib winspool.lib comdlg32.lib advapi32.lib shell32.lib ole32.lib oleaut32.lib uuid.lib odbc32.lib odbccp32.lib /nologo /subsystem:console /debug /machine:I386 /pdbtype:sept + +!ENDIF + +# Begin Target + +# Name "simple_win32 - Win32 Release" +# Name "simple_win32 - Win32 Debug" +# Begin Group "Source Files" + +# PROP Default_Filter "cpp;c;cxx;rc;def;r;odl;idl;hpj;bat" +# Begin Source File + +SOURCE=.\demo\simple_win32.c +# End Source File +# End Group +# Begin Group "Header Files" + +# PROP Default_Filter "h;hpp;hxx;hm;inl" +# End Group +# Begin Group "Resource Files" + +# PROP Default_Filter "ico;cur;bmp;dlg;rc2;rct;bin;rgs;gif;jpg;jpeg;jpe" +# End Group +# End Target +# End Project diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Repository new file mode 100755 index 00000000..1b465e88 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Entries new file mode 100755 index 00000000..8a0902d7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Entries @@ -0,0 +1,27 @@ +D/CVS//// +D/FIG//// +D/GD//// +D/PS//// +D/Win32//// +D/X11//// +/g2.h/1.1/Tue Jun 14 20:44:20 2005// +/g2_config.h/1.1/Thu Mar 11 23:08:59 2004// +/g2_control_pd.c/1.1/Tue Jun 14 20:44:20 2005// +/g2_control_pd.h/1.1/Tue Jun 14 20:44:20 2005// +/g2_device.c/1.1/Tue Apr 17 20:16:38 2001// +/g2_device.h/1.1/Tue Apr 17 20:16:38 2001// +/g2_fif.c/1.1/Wed Apr 7 22:27:44 2004// +/g2_funix.h/1.1/Tue Jun 14 20:44:20 2005// +/g2_graphic_pd.c/1.1/Tue Feb 22 21:44:46 2005// +/g2_graphic_pd.h/1.1/Thu Feb 26 23:50:24 2004// +/g2_physical_device.c/1.1/Tue Apr 17 20:16:38 2001// +/g2_physical_device.h/1.1/Tue Apr 17 20:16:38 2001// +/g2_splines.c/1.1/Tue Feb 22 21:41:40 2005// +/g2_ui_control.c/1.1/Tue Jun 14 20:44:20 2005// +/g2_ui_device.c/1.1/Tue Mar 23 00:20:27 2004// +/g2_ui_graphic.c/1.1/Tue Mar 23 23:50:40 2004// +/g2_ui_virtual_device.c/1.1/Tue Mar 23 00:20:27 2004// +/g2_util.c/1.1/Wed Apr 7 21:51:25 2004// +/g2_util.h/1.1/Thu Mar 11 23:01:03 2004// +/g2_virtual_device.c/1.1/Tue Apr 17 20:16:38 2001// +/g2_virtual_device.h/1.1/Tue Apr 17 20:16:38 2001// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Repository new file mode 100755 index 00000000..7d4eeb98 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Repository new file mode 100755 index 00000000..d9e68a82 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/FIG/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Entries new file mode 100755 index 00000000..0e5e0f9e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Entries @@ -0,0 +1,5 @@ +D/CVS//// +/g2_FIG.c/1.1/Mon Apr 5 21:40:53 2004// +/g2_FIG.h/1.1/Thu Apr 1 22:29:34 2004// +/g2_FIG_P.h/1.1/Sat Apr 3 23:26:57 2004// +/g2_FIG_funix.h/1.1/Sat Apr 3 22:58:26 2004// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Repository new file mode 100755 index 00000000..1a7809ed --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/FIG diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.c new file mode 100755 index 00000000..15707388 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.c @@ -0,0 +1,486 @@ +/***************************************************************************** +** Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include +#include +#include +#include + +#include "g2.h" +#include "g2_device.h" +#include "g2_util.h" +#include "g2_config.h" + +#include "g2_FIG.h" +#include "g2_FIG_P.h" +#include "g2_FIG_funix.h" + +#ifndef PI +#define PI 3.14159265358979323846 +#endif /* PI */ + +static int N_FIG=0; +static g2_FIG_device *g2_FIG_dev=NULL; + +/** + * \ingroup physdev + * \defgroup FIG FIG + * + * FIG devices generate output in the FIG 3.2 format. For more details + * about FIG format and xfig application please visit http://www.xfig.org . + * + * \note FIG is a vector-oriented (as oposed to pixel-oriented) format. + * Therefore ::g2_image function and splines are not optimally supported. + */ + + +/** + * + * Create a FIG device. g2 uses A4 paper size (landscape orientation) as default. + * + * \param file_name fig file name + * + * \return physical device id + * + * \ingroup FIG + */ +G2L int g2_open_FIG(const char *file_name) +{ + g2_FIG_device *figout=NULL; + int pid=-1, i; + int vid; + FILE *fp; + + if((fp=fopen(file_name, "w"))==NULL) { + g2_log(Error, "g2_attach_PS: Error! Can not open file '%s'\n", + file_name); + return -1; + } + + if(g2_FIG_dev==NULL) { + g2_FIG_dev=g2_malloc(sizeof(g2_FIG_device)); + N_FIG=1; /* first FIG device */ + figout=&g2_FIG_dev[N_FIG-1]; + pid=0; + } else { + for(i=0;ifp=fp; + figout->pen_color=1; + figout->thickness=-1; + figout->font_size=-1; + figout->N_inks=0; + + /* write file header (incl. color placeholder) */ + g2_FIG_write_file_header(figout); + + /* g2 settings callbacks */ + g2_allocate_basic_colors(vid); + g2_pen(vid, 1); + g2_set_line_width(vid, 1); + g2_set_dash(vid, 0, NULL); + g2_set_font_size(vid, 12); + + return vid; +} + + + +/* + * + * Write header for fig file + * + */ +int g2_FIG_write_file_header(g2_FIG_device *fig) +{ + int i; + + fprintf(fig->fp, "#FIG 3.2\n"); + fprintf(fig->fp, "#Creator: g2 %s\n", G2_VERSION); + + fprintf(fig->fp, "Landscape\n"); + fprintf(fig->fp, "Flush Left\n"); + fprintf(fig->fp, "Metric\n"); + fprintf(fig->fp, "A4\n"); + fprintf(fig->fp, "100\n"); + fprintf(fig->fp, "Single\n"); + fprintf(fig->fp, "-2\n"); + fprintf(fig->fp, "1200 2\n"); + + /* write placeholder for all colors */ + fgetpos(fig->fp, &(fig->color_file_pos)); + for(i=0;i<512;i++) + fprintf(fig->fp, "0 %3d #%02x%02x%02x\n",32+i, 0xff, 0xff, 0xff); + + return 0; +} + + +/* + * + * Delete FIG device + * + */ +int g2_FIG_delete(int pid, void *pdp) +{ + int i; + g2_FIG_device *fig=&g2_FIG_dev[pid]; + + /* now write all defined colors to the reserved place */ + fsetpos(fig->fp, &(fig->color_file_pos)); + for(i=0;iN_inks;i++) { + fprintf(fig->fp, "0 %3d #%02x%02x%02x\n", + 32+i, + (int)fig->inks[i].red, + (int)fig->inks[i].green, + (int)fig->inks[i].blue); + } + + fclose(fig->fp); + fig->fp=NULL; /* free place */ + return 0; +} + + + +int g2_FIG_ink(int pid, void *pdp, + double red, double green, double blue) +{ + /* the fig pen space is betwen 32 and 543, total of 512 colors, + in g2 implementation from 0000 to 0777. + On the other hand ink space is between #000000 and #ffffff. */ + + g2_FIG_device *fig=&g2_FIG_dev[pid]; + + if(fig->N_inks>=512) + return -1; + + fig->inks[fig->N_inks].red = red*0xff; + fig->inks[fig->N_inks].green = green*0xff; + fig->inks[fig->N_inks].blue = blue*0xff; + + return fig->N_inks++; +} + + + +int g2_FIG_pen(int pid, void *pdp, int color) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + + if(color>=fig->N_inks) { + return -1; + } + + fig->pen_color = 32+color; + + return 0; +} + + + +int g2_FIG_set_background(int pid, void *pdp, int color) +{ + return -1; +} + + + +int g2_FIG_clear_palette(int pid, void *pdp) +{ + return -1; +} + + + +int g2_FIG_set_line_width(int pid, void *pdp, int w) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fig->thickness = w*80./1200.; + return 0; +} + + + +int g2_FIG_set_dash(int pid, void *pdp, int N, int *data) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + int black, white; + + if(N==0 || data==NULL) { + fig->line_style=0; + fig->style_val=-1; + return 0; + } + if(N<2) { + return -1; + } + black = data[0]*80./1200.; /* FIG format has no sofistificated dash concept */ + white = data[1]*80./1200.; /* we will do out best */ + if(black<4) { + fig->line_style = 2; + } else { + fig->line_style = 1; + } + fig->style_val = white; + return 0; +} + + + +int g2_FIG_set_font_size(int pid, void *pdp, int size) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fig->font_size = size*72./1200.; + return 0; +} + + + +int g2_FIG_clear(int pid, void *pdp) +{ + return -1; +} + + + +int g2_FIG_flush(int pid, void *pdp) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fflush(fig->fp); + return 0; +} + + + +int g2_FIG_plot(int pid, void *pdp, int x, int y) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fprintf(fig->fp, "2 1 0 %d %d -1 1 1 -1 -1 1 0 -1 0 0 2\n", + 1, fig->pen_color); + fprintf(fig->fp, " %d %d\n %d %d\n", x, y, x+1, y); + return 0; +} + + + +int g2_FIG_line(int pid, void *pdp, int x1, int y1, int x2, int y2) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fprintf(fig->fp, "2 1 %d %d %d -1 1 1 -1 %d 1 0 -1 0 0 2\n", + fig->line_style, fig->thickness, fig->pen_color, fig->style_val); + fprintf(fig->fp, " %d %d\n %d %d\n", x1, y1, x2, y2); + return 0; +} + + + +int g2_FIG_poly_line(int pid, void *pdp, int N, int *points) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + int i; + + fprintf(fig->fp,"2 1 %d %d %d -1 1 1 -1 %d 1 0 -1 0 0 %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->style_val, N); + for(i=0;i<2*N;i+=2) { + fprintf(fig->fp, " %d %d\n", points[i], points[i+1]); + } + return 0; +} + + + +int g2_FIG_polygon(int pid, void *pdp, int N, int *points) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + int i; + + if(N<2) { + return -1; + } + + fprintf(fig->fp,"2 3 %d %d %d -1 1 1 -1 %d 1 0 -1 0 0 %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->style_val, N+1); + for(i=0;i<2*N;i+=2) { + fprintf(fig->fp, " %d %d\n", points[i], points[i+1]); + } + fprintf(fig->fp, " %d %d\n", points[0], points[1]); + return 0; +} + + + +int g2_FIG_filled_polygon(int pid, void *pdp, int N, int *points) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + int i; + + if(N<2) { + return -1; + } + + fprintf(fig->fp,"2 3 %d %d %d %d 1 1 20 %d 1 0 -1 0 0 %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->pen_color, + fig->style_val, N+1); + for(i=0;i<2*N;i+=2) { + fprintf(fig->fp, " %d %d\n", points[i], points[i+1]); + } + fprintf(fig->fp, " %d %d\n", points[0], points[1]); + return 0; +} + + +int g2_FIG_arc(int pid, void *pdp, + int x, int y, + int r1, int r2, + double a1, double a2) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + double a0, d; + double a0_rad, da_rad; + int N, i; + + a0=fmod(a1, 360.) + (a1<0? 360:0); /* map a1 to [0, 360) */ + d=a2>a1? a2-a1:a2-a1+360; + + N=3+d/18; + + a0_rad = a0*2.*PI/360.; + da_rad = d*2.*PI/360./(N-1); + + fprintf(fig->fp, "3 2 %d %d %d -1 1 -1-1 %d 0 0 0 %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->style_val, N); + for(i=0;ifp, " %d %d\n", + (int)(x+r1*cos(a0_rad+i*da_rad)), + (int)(y-r2*sin(a0_rad+i*da_rad))); + } + fprintf(fig->fp, " -1"); + for(i=1;ifp, " -1"); + } + fprintf(fig->fp, " -1\n"); + + return 0; +} + + +int g2_FIG_filled_arc(int pid, void *pdp, + int x, int y, + int r1, int r2, + double a1, double a2) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + double a0, d; + double a0_rad, da_rad; + int N, i; + + a0=fmod(a1, 360.) + (a1<0? 360:0); /* map a1 to [0, 360) */ + d=a2>a1? a2-a1:a2-a1+360; + + N=3+d/18; + + a0_rad = a0*2.*PI/360.; + da_rad = d*2.*PI/360./(N-1); + + fprintf(fig->fp, "3 2 %d %d %d %d 1 -1 20 %d 0 0 0 %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->pen_color, + fig->style_val, N+2); + for(i=0;ifp, " %d %d\n", + (int)(x+r1*cos(a0_rad+i*da_rad)), (int)(y-r2*sin(a0_rad+i*da_rad))); + } + fprintf(fig->fp, " %d %d\n", x, y); + fprintf(fig->fp, " %d %d\n", + (int)(x+r1*cos(a0_rad+0*da_rad)), + (int)(y-r2*sin(a0_rad+0*da_rad))); + fprintf(fig->fp, " 0"); + for(i=1;ifp, " -1"); + } + fprintf(fig->fp, " 0 0 0\n"); + + return 0; +} + + +int g2_FIG_ellipse(int pid, void *pdp, + int x, int y, + int r1, int r2) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fprintf(fig->fp,"1 1 %d %d %d -1 1 -1 -1 %d 1 0.0 %d %d %d %d %d %d %d %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->style_val, + x, y, r1, r2, x, y, x+r1, y+r2); + + return 0; +} + + +int g2_FIG_filled_ellipse(int pid, void *pdp, + int x, int y, + int r1, int r2) +{ + g2_FIG_device *fig=&g2_FIG_dev[pid]; + fprintf(fig->fp,"1 1 %d %d %d %d 1 -1 20 %d 1 0.0 %d %d %d %d %d %d %d %d\n", + fig->line_style, fig->thickness, fig->pen_color, fig->pen_color, fig->style_val, + x, y, r1, r2, x, y, x+r1, y+r2); + + return 0; +} + + +int g2_FIG_draw_string(int pid, void *pdp, + int x, int y, const char *text) +{ + const char *c; + g2_FIG_device *fig=&g2_FIG_dev[pid]; + if(fig->font_size<=0) + return 0; + fprintf(fig->fp,"4 0 %d 1 -1 0 %d 0 5 %d %d %d %d ", + fig->pen_color, fig->font_size, fig->font_size, fig->font_size*strlen(text), x, y); + for(c=text;*c;c++) { + if(*c=='\\') + fputc('\\', fig->fp); /* escape \\ */ + fputc(*c, fig->fp); + } + fprintf(fig->fp,"\\001\n"); + return 0; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.h new file mode 100755 index 00000000..908d8f38 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.h @@ -0,0 +1,54 @@ +/***************************************************************************** +** Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_FIG_H +#define _G2_FIG_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + +G2L int g2_open_FIG(const char *file_name); + + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_FIG_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG.o new file mode 100755 index 0000000000000000000000000000000000000000..73279fc8e894e6761d71bfeb68703c1568420763 GIT binary patch literal 20580 zcmb_^3w)H-nfG~TCYdn_Nnip52{1r_03jDZXWMsXR-zbYKXer7S(Wh$2%*QwtoG9^uDQJ3RTC7fXGXvisA> zS(fkVSdj0dDrgOWBr?FpQ-C(oO`(?!?FW6=GTuweTw}|)FCnvE`@R6Ktj_n99v5e3 zL)vy&YhRY{gIDuxZAk%ZXBOM6OBq7-Wwy-49qzm%FV*BRk+Aps>~cQ)&O^n1emu($ zc$?EXJ1`s2w{JBG3-Ys(*9;Im2_-u|I}e9%IoN(UP}+6ln#w~RA9X%I2I6Y@{+n3q zot35M+0HX!mA)h8XVHk~p~=&cXIibJ{Da%OvToZAC9x}5?e>qdZtF{I2%EUHYwFuu zhjn~ddURL&G?jJR2yn`F94J6AI}Y-5YWJ2uOzqCPZ6Fx?lq%}#`BUlZa51m6Yrkqa zScYOY>18_qIVeKuN1$eucHz^fKRvPXvj{EsoALEhXV;3-SNP`0{ZMT z6}#IH&$w|-u<}sn28Bjuz?$(0!{~Ua<6~r$MLkL$VZz?~_zNVs{Or{3&Kadyx4%bh za(ugRI;vG8o?^RDi{owB>~n7P}#ZmH;8lim3Y<+Gldod(}>051c~2K2Qb za-*2hSrMoJlzy1h|E9h`McWQ0dgKw{O0^$G574RG)%o;jQZV1Nf8Yx*)Lv;1PnKt& zEYCez9_8hD0DF3{t z@$y(_z=2vkdZTLMqJv3;EsRIhnSBZ+9mV1FV>$)lDx*+vSXDw z)~_*&@9Dbzc-B1!FMI8AD?0GV%xp>>nVG|`Q`*&j*vH9Yk@oSHKOcAZq-22KlR~kc zV?A3xg5i(4kBaGY-5>Teo;zN7wx{tUjMd|_J?)>kvmWfqdZw$aV`lcLqo@8%{#SFr zfBzwg*AZW=53P6i$-yThk{nWd_Z7JyTDnOkzziMWMf2qgmz(VCpsm+p%AO~VmUc;^ z?e?Pmf{w~_;mSmp>uCEV)|S(;^>gb`Y-@IGwujx@UgLcGO5h48o|xNK+Y!YyTw(2R zB`1p6cZ;4jvN?w)q+*rlO1omvz4h~s5A62ucn8yNzHVA^0Y+!%K!1)g4EuV8jLpv0 zqifX#)??*)TD&|LAUjsh${De8Bd%Raa<=_&J_em_fB$ysduJtQ|GZdbc6h5vou1|~ zx8zzM$0~C4WSkSLU?#F-6~>_o9UmyZnAgrkr)O~cC+e2T9g^nQ@|@V5r*r~io~NF@ zmBuhnwZG&_t~d2B+ulgb2AD__?PFXs88WjK8pV34{k*07W!BDrgi>T*uN}Fuxh8jW zjjMBwt8+~5tmq`^4Y-+7D?r_i4A2>P>xn+Z&L5k(}5pBkw}9 zvxH5OoeqwnJhL{){3hdF2UUnbWCAwh(|QY0W$k?25m2592ysz$jse-RdyaNPN6*$% zJqJ+i!h1yk>U)lra!NWS6VeHAj&-Nxlhb(Oc;(@q##1NtY7r|xeB$V-WAi%7??(~y z)-fbE7ad*a_=0ZE;JLv7*Q5LTslOgCzaQRKzIaeKX6G55G9zx}Z1#KMDItbttus>B0``}(b$G1bSs*f@L> zPJ^GZ@8TQS_O16@w_Fu#yMK`xDV;AuUVWLGi`sf(UVRoYJ1)4QH zu5}RkDd_Z+BGSp7p6OV<0xvG+EQeJev=V*DT7bSg%S?-UnahsNGE3^L?D%r$vX{GF zI~=(6CH*O|{V6p5OfmlC!xiprCc_oF6ELpinq?`+0H;T6vu`m3PSlrlOYgMJ{AK2s z_74hWv9dQ9xz<~;H5u3&@8qOpA0D%Q+HJO1dE8#D&d=%i43@Aq^Sq5knIOX~(Y}2z z+kV7%1MlbV+WzV4=ykDF9@sruFC4TJm-USQw%6Ov=!=90X^`_US1J^G_rk-4GDq_K zplj%ZKNRY21Xb@psI0zLc4|L-j>`0>yE6x8D&@*o?#%S`t8t;?M$u=Ao&lgvOP`)T z->+0kmP*%!RKI2UDNT-2-abYsWxjt3Zf<;12dGk)4TPvIm?nZ+Njff`{1nL;uIBrT zp{Ebk+OnAmSt`wi0nD6gv^|Q)Q{qmH!HW$#rlatUqa3xFR4guGJ4owIvH7vnX zD&R1e;xsp0%prwTI70LbI#Lws1m`CZijETfB072q0xH#EC^aTUl_Gfs>DF=_a>q^v z#wz1_dl5jQ$0s~csxYBcsR@Fh5wFRZk%4;|CxHspBU$KAfJ*6m7qypHf_VN9h*lqL zAYKRJ`WJk7ysl)?KS6W64?stXU(j6d zUf55`5j4-ch1~vv2D~*0E@hyg`QC1Nl`Ck0cQ(0$1TFObGtt4;AOP3M67Lpj9%2pC z=wvT<#wo)jqAA{8;H6*Zq)t+v7AWwnqRXx}cP_>h5s{rUglqox@rEi_)PbgFd+X` zFw@8XD{wRYPvA4lkNl}@|9^qo*MBcQ`}v3B)9-%?wQ~GVq1@m9M`#}4e+;$;`Ul`M z*Z%|P8RY*M<;(roL2@wW9;Nd9Bk(!Ip9=a=*<$;SJ_W%k7sctyaqTB&es9`8I3^xtx$vh4j_Xug; 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+ unsigned char green; + unsigned char blue; +} g2_FIG_inks; + +typedef struct _g2_FIG_device { + FILE *fp; /* output file pointer */ + int pen_color; /* current pen */ + int thickness; /* line thickness */ + int font_size; /* font size */ + int line_style; /* line style according to fig format */ + int style_val; /* line style value acc. to fig format */ + + g2_FIG_inks inks[512]; /* 512 user defined colors */ + int N_inks; /* number of allocated colors */ + fpos_t color_file_pos; /* file position of colors, ftell */ +} g2_FIG_device; + + + +int g2_FIG_write_file_header(g2_FIG_device *figd); +int g2_FIG_delete(int pid, void *pdp); +int g2_FIG_ink(int pid, void *pdp, + double red, double green, double blue); +int g2_FIG_pen(int pid, void *pdp, int color); +int g2_FIG_set_background(int pid, void *pdp, int color); +int g2_FIG_reset_palette(int pid, void *pdp); +int g2_FIG_clear_palette(int pid, void *pdp); +int g2_FIG_set_line_width(int pid, void *pdp, int w); +int g2_FIG_set_dash(int pid, void *pdp, int N, int *data); +int g2_FIG_set_font_size(int pid, void *pdp, int size); +int g2_FIG_clear(int pid, void *pdp); +int g2_FIG_flush(int pid, void *pdp); +int g2_FIG_plot(int pid, void *pdp, int x, int y); +int g2_FIG_line(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_FIG_poly_line(int pid, void *pdp, int N, int *points); +int g2_FIG_polygon(int pid, void *pdp, int N, int *points); +int g2_FIG_filled_polygon(int pid, void *pdp, int N, int *points); +int g2_FIG_arc(int pid, void *pdp, + int x, int y, + int r1, int r2, + double a1, double a2); +int g2_FIG_filled_arc(int pid, void *pdp, + int x, int y, + int r1, int r2, + double a1, double a2); +int g2_FIG_ellipse(int pid, void *pdp, + int x, int y, + int r1, int r2); +int g2_FIG_filled_ellipse(int pid, void *pdp, + int x, int y, + int r1, int r2); +int g2_FIG_draw_string(int pid, void *pdp, + int x, int y, const char *text); + +#endif /* _G2_FIG_P_H */ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG_funix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG_funix.h new file mode 100755 index 00000000..ac0ddfa3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/FIG/g2_FIG_funix.h @@ -0,0 +1,56 @@ +/***************************************************************************** +** Copyright (C) 1998-2004 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_FIG_FUNIX_H +#define _G2_FIG_FUNIX_H + +#include "g2_FIG_P.h" +#include "g2_physical_device.h" + +const g2_funix_fun g2_FIG_funix[] = { + { g2_Delete, g2_FIG_delete }, + { g2_Ink, g2_FIG_ink }, + { g2_Pen, g2_FIG_pen }, + { g2_SetBackground, NULL }, + { g2_ClearPalette, NULL }, + { g2_SetLineWidth, g2_FIG_set_line_width }, + { g2_SetDash, g2_FIG_set_dash }, + { g2_SetFontSize, g2_FIG_set_font_size }, + { g2_Clear, g2_FIG_clear }, + { g2_Flush, g2_FIG_flush }, + { g2_Save, g2_FIG_flush }, + { g2_Plot, g2_FIG_plot }, + { g2_Line, g2_FIG_line }, + { g2_PolyLine, g2_FIG_poly_line }, + { g2_Polygon, g2_FIG_polygon }, + { g2_FilledPolygon, g2_FIG_filled_polygon }, + { g2_Rectangle, NULL }, + { g2_FilledRectangle, NULL }, + { g2_Triangle, NULL }, + { g2_FilledTriangle, NULL }, + { g2_Arc, g2_FIG_arc }, + { g2_FilledArc, g2_FIG_filled_arc }, + { g2_Ellipse, g2_FIG_ellipse }, + { g2_FilledEllipse, g2_FIG_filled_ellipse }, + { g2_Circle, NULL }, + { g2_FilledCircle, NULL }, + { g2_String, g2_FIG_draw_string }, + { g2_FUNIX_NULL, NULL } }; + + +#endif /* _G2_FIG_FUNIX_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Repository new file mode 100755 index 00000000..df74fdf8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/GD/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Entries new file mode 100755 index 00000000..b1d20dce --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Entries @@ -0,0 +1,5 @@ +D/CVS//// +/g2_gd.c/1.1/Tue Feb 22 03:51:05 2005// +/g2_gd.h/1.1/Tue Mar 23 23:50:40 2004// +/g2_gd_P.h/1.1/Thu Feb 26 23:50:24 2004// +/g2_gd_funix.h/1.1/Tue Feb 22 03:51:06 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Repository new file mode 100755 index 00000000..9d8874e4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/GD diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.c new file mode 100755 index 00000000..2bb23703 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.c @@ -0,0 +1,348 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ + +#include +#include +#include + +#include "g2.h" +#include "g2_device.h" +#include "g2_util.h" +#include "g2_config.h" + +#include "g2_gd_P.h" +#include "g2_gd.h" + +#define PDP ((struct g2_gd_STRUCT *)pdp) + +#include "g2_gd_funix.h" + +#ifndef PI +#define PI 3.14159265358979323846 +#endif /* PI */ + + +/** + * \ingroup physdev + * \defgroup GD GD + */ + + +/** + * + * Create a GD device. + * + * \param filename output file name + * \param width width + * \param height height + * \param gd_type file type, see ::g2_gd_type + * + * \return physical device id + * + * \ingroup GD + */ +int g2_open_gd(const char *filename, int width, int height, enum g2_gd_type gd_type) +{ + int pid=-1; + g2_gd_STRUCT *pdp; + + pdp = (g2_gd_STRUCT *)malloc(sizeof(g2_gd_STRUCT)); + + pdp->width = width; + pdp->height = height; + pdp->gd_type = gd_type; + pdp->im = gdImageCreate(width,height); + pdp->f = fopen(filename,"wb"); + pdp->NoOfInks = 0; + pdp->BackCol = 0; + + pid = g2_register_physical_device(pid, pdp, + g2_IntCoor, g2_gd_funix, + 1.0, -1.0, + 0.0, height-1); + + g2_gd_Clear(pid,pdp); + g2_set_line_width(pid, 0.0); + g2_set_font_size(pid, 12.0); + g2_allocate_basic_colors(pid); + g2_pen(pid, 1); + + return pid; +} + + + +int g2_gd_Alloc_Basic(int pid, void *pdp) + { + int icol; + for (icol=0;icol<32;icol++) + gdImageColorAllocate(PDP->im,g2_Basic_Colors[icol][0]/256,g2_Basic_Colors[icol][1]/256,g2_Basic_Colors[icol][2]/256); + PDP->NoOfInks = 32; + return 0; + } + + +int g2_gd_Clear(int pid, void *pdp) + { + gdImageFilledRectangle(PDP->im, 0, 0, PDP->width, PDP->height, PDP->BackCol); + return 0; + } + +int g2_gd_Save(int pid, void *pdp) + { + if (PDP->gd_type == g2_gd_png) + gdImagePng(PDP->im,PDP->f); + else if (PDP->gd_type == g2_gd_jpeg) + gdImageJpeg(PDP->im,PDP->f,-1); + fflush(PDP->f); + rewind(PDP->f); + return 0; + } + +int g2_gd_Delete(int pid, void *pdp) + { + g2_gd_Save(pid,pdp); + fclose(PDP->f); + gdImageDestroy(PDP->im); + free(PDP); + return 0; + } + +int g2_gd_Flush(int pid, void *pdp) + { + return 0; + } + +int g2_gd_Pen(int pid, void *pdp, int color) + { + PDP->CurCol = color; + return 0; + } + +int g2_gd_Ink(int pid, void *pdp, double red, double green, double blue) + { + if(PDP->NoOfInks == 256) + return -1; + else + PDP->NoOfInks++; + return gdImageColorAllocate(PDP->im,(int)(255*red),(int)(255*green),(int)(255*blue)); + } + +int g2_gd_ClearPalette(int pid, void *pdp) + { + int i; + for (i=0;iNoOfInks;i++) + gdImageColorDeallocate(PDP->im,i); + PDP->NoOfInks = 0; + return 0; + } + +int g2_gd_ResetPalette(int pid, void *pdp) + { + g2_gd_ClearPalette(pid,pdp); + g2_gd_Alloc_Basic(pid,pdp); + return 0; + } + +int g2_gd_SetBackground(int pid, void *pdp, int color) + { + PDP->BackCol = color; + return 0; + } + +int g2_gd_SetLineWidth(int pid, void *pdp, int w) + { + PDP->LineWidth = w; + return 0; + } +/* { + if (PDP->brush != NULL) + { + gdImageDestroy(PDP->brush); + } + PDP->brush = gdImageCreate(w,w); + gdImageColorTransparent(PDP->brush,0); + gdImageColorAllocate(PDP->brush,0,0,0); + gdImageColorAllocate(PDP->brush, + gdImageRed(PDP->im,PDP->CurCol), + gdImageGreen(PDP->im,PDP->CurCol), + gdImageBlue(PDP->im,PDP->CurCol)); + gdImageArc(PDP->brush, w/2, w/2, w/2,w/2, 0, 360, 1); + gdImageFill(PDP->brush,w/2,w/2,1); + gdImageSetBrush(PDP->im, PDP->brush); + PDP->OldCol = PDP->CurCol; + PDP->CurCol = gdBrushed; + } + else + { + PDP->CurCol = PDP->OldCol; + } + return 0; + } +*/ + +int g2_gd_SetDash(int pid, void *pdp, int n, char *data) + { + return 0; + } + +int g2_gd_SetDashX(int pid, void *pdp, int N, double *dashes) + { + return 0; + } + +int g2_gd_SetFontSize(int pid, void *pdp, int size) + { + if (size <=10) + PDP->FontSize = gdFontTiny; + else if (size <=12) + PDP->FontSize = gdFontSmall; + else if (size <=13) + PDP->FontSize = gdFontMediumBold; + else if (size <=15) + PDP->FontSize = gdFontLarge; + else + PDP->FontSize = gdFontGiant; + return 0; + } + +int g2_gd_Plot(int pid, void *pdp, int x, int y) + { + gdImageSetPixel(PDP->im, x, y, PDP->CurCol); + return 0; + } + +int g2_gd_Line(int pid, void *pdp, int x1, int y1, int x2, int y2) + { + if (PDP->LineWidth <= 1) + gdImageLine(PDP->im, x1, y1, x2, y2, PDP->CurCol); + else + { + float dx,dy,l; + gdPoint points[4]; + dx = -(float)(y2-y1); + dy = (float)(x2-x1); + l = (float)(PDP->LineWidth/sqrt(dy*dy+dx*dx)/2.); + dx = dx*l; + dy = dy*l; + points[0].x = (int)(x1+dx); + points[0].y = (int)(y1+dy); + points[1].x = (int)(x1-dx); + points[1].y = (int)(y1-dy); + points[2].x = (int)(x2-dx); + points[2].y = (int)(y2-dy); + points[3].x = (int)(x2+dx); + points[3].y = (int)(y2+dy); + gdImageFilledPolygon(PDP->im,points,4,PDP->CurCol); + } + return 0; + } + +int g2_gd_PolyLine(int pid, void *pdp, int N, int *points) + { + return 0; + } + +int g2_gd_Triangle(int pid, void *pdp, int x1, int y1, + int x2, int y2, + int x3, int y3) + { + return 0; + } + +int g2_gd_FilledTriangle(int pid, void *pdp, int x1, int y1, + int x2, int y2, + int x3, int y3) + { + return 0; + } + +int g2_gd_Rectangle(int pid, void *pdp, int x, int y, int x2, int y2) + { + gdImageRectangle(PDP->im, x, y, x2, y2, PDP->CurCol); + return 0; + } + +int g2_gd_FilledRectangle(int pid, void *pdp, int x, int y, int x2, int y2) + { + gdImageFilledRectangle(PDP->im, x, y, x2, y2, PDP->CurCol); + return 0; + } + +int g2_gd_Polygon(int pid, void *pdp, int N, int *points) + { + return 0; + } + +int g2_gd_FilledPolygon(int pid, void *pdp, int N, int *points) + { + gdPoint *GIFPolygon; + int i; + GIFPolygon = (gdPoint *)malloc(N*sizeof(gdPoint)); + for (i=0;iim,GIFPolygon,N,PDP->CurCol); + free(GIFPolygon); + return 0; + } + +int g2_gd_Circle(int pid, void *pdp, int x, int y, int r) + { + gdImageArc(PDP->im, (int)x, (int)y, (int)r, (int)r, 0, 360, PDP->CurCol); + return 0; + } + +int g2_gd_FilledCircle(int pid, void *pdp, int x, int y, int r) + { + return 0; + } + +int g2_gd_Ellipse(int pid, void *pdp, int x, int y, int r1, int r2) + { + return 0; + } + +int g2_gd_FilledEllipse(int pid, void *pdp, int x, int y, int r1, int r2) + { + return 0; + } + +int g2_gd_Arc(int pid, void *pdp, int x, int y, int r1, int r2, double a1, double a2) + { + gdImageArc(PDP->im,x,y,2*r1,2*r2,dtoi(a1),dtoi(a2),PDP->CurCol); + return 0; + } + +int g2_gd_FilledArc(int pid, void *pdp, int x, int y, + int r1, int r2, + double a1, double a2) + { + return 0; + } + +int g2_gd_DrawString(int pid, void *pdp, int x, int y, const char *text) + { + + gdImageString(PDP->im,PDP->FontSize,x,y+2-PDP->FontSize->h,(unsigned char *)text,PDP->CurCol); + return 0; + } + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.h new file mode 100755 index 00000000..d9588a79 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd.h @@ -0,0 +1,67 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +/* This is g2_GIF.h */ +#ifndef _G2_GD_H +#define _G2_GD_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + +#include + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + +/** + * g2 gd bitmap types + * + * \ingroup GD + */ +enum g2_gd_type { + g2_gd_jpeg = 0, /**< jpeg */ + g2_gd_png = 1 /**< png */ +}; + + +G2L int g2_open_gd(const char *filename, int width, int height,enum g2_gd_type gd_type); + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + + +#endif /* _G2_GD_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_P.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_P.h new file mode 100755 index 00000000..95e56c7c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_P.h @@ -0,0 +1,118 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _g2_GD_P_H +#define _g2_GD_P_H + +#include +#include +#include +#include +#include +#include +#include "g2_config.h" +#include "g2_gd.h" + + static unsigned short g2_Basic_Colors[32][3] = { + {65535,65535,65535},{0,0,0}, + {44461,55512,59110},{0,65535,65535},{0,0,65535}, + {0,0,32896},{61166,33410,61166}, + {65535,0,65535},{41120,8224,61680},{65535,49344,52171}, + {61680,59110,35980},{32639,65535,54484}, + {39064,64507,39064},{0,65535,0},{12850,52685,12850}, + {39578,52685,12850},{44461,65535,12079},{65535,65535,0}, + {65535,55255,0},{61166,56797,33410},{56026,42405,8224},{47288,34438,2827}, + {42405,10794,10794},{53970,26985,7710}, + {52685,34181,16191},{65535,32639,20560}, + {61680,32896,32896},{64250,32896,29298}, + {65535,35980,0},{65535,42405,0},{65535,17733,0}, + {65535,0,0}}; + + +typedef struct g2_gd_STRUCT { + int height; + int width; + FILE *f; + gdImagePtr im; + gdImagePtr brush; + int LineWidth; + int NoOfInks; + int Inks[256]; + int CurCol; + int OldCol; + int BackCol; + gdFontPtr FontSize; + enum g2_gd_type gd_type; + } g2_gd_STRUCT; + + + +int g2_gd_init_gd(int pid, void *pdp, int vid, int width,int height); +int g2_gd_init_gdX(int pid, void *pdp, + int width, int height, + int xposition, int yposition, + char *windowname, char *iconname, + char *icondata, int iconwidth, int iconheight); +int g2_gd_Delete(int pid, void *pdp); +int g2_gd_Clear(int pid, void *pdp); +int g2_gd_Flush(int pid, void *pdp); +int g2_gd_Ink(int pid, void *pdp, + double red, double green, double blue); +int g2_gd_ClearPalette(int pid, void *pdp); +int g2_gd_ResetPalette(int pid, void *pdp); +int g2_gd_SetBackground(int pid, void *pdp, int color); +int g2_gd_Pen(int pid, void *pdp, int color); +int g2_gd_Paper(int pid, void *pdp, int color); +int g2_gd_SetLineWidth(int pid, void *pdp, int w); +int g2_gd_SetDash(int pid, void *pdp, int n, char *data); +int g2_gd_SetFontSize(int pid, void *pdp, int size); +int g2_gd_Plot(int pid, void *pdp, int x, int y); +int g2_gd_Line(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_gd_PolyLine(int pid, void *pdp, int N, int *p); +int g2_gd_Polygon(int pid, void *pdp, int N, int *p); +int g2_gd_FilledPolygon(int pid, void *pdp, int N, int *p); +int g2_gd_Triangle(int pid, void *pdp, + int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_gd_FilledTriangle(int pid, void *pdp, int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_gd_Rectangle(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_gd_FilledRectangle(int pid, void *pdp, + int x1, int y1, int x2, int y2); +int g2_gd_Circle(int pid, void *pdp, int x, int y, int r); +int g2_gd_FilledCircle(int pid, void *pdp, int x, int y, int r); +int g2_gd_Arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_gd_FilledArc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_gd_Ellipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_gd_FilledEllipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_gd_DrawString(int pid, void *pdp, int x, int y, const char *text); + +int g2_gd_AllocateBasicColors(int pid, void *pdp); + + + +#endif /* _g2_GD_P_H */ + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_funix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_funix.h new file mode 100755 index 00000000..1ba0692d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/GD/g2_gd_funix.h @@ -0,0 +1,54 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _g2_GD_TOKEN_FUN_H +#define _g2_GD_TOKEN_FUN_H + + +#include "g2_virtual_device.h" +#include "g2_gd_P.h" + +const g2_funix_fun g2_gd_funix[] = + {{g2_Delete,g2_gd_Delete}, + {g2_Ink, g2_gd_Ink}, + {g2_Pen,g2_gd_Pen}, + {g2_SetBackground,g2_gd_SetBackground}, + {g2_ClearPalette,g2_gd_ClearPalette}, + {g2_SetLineWidth,g2_gd_SetLineWidth}, + /* {g2_SetDash,g2_gd_SetDash}, */ + {g2_SetFontSize,g2_gd_SetFontSize}, + {g2_Clear,g2_gd_Clear}, + {g2_Flush,g2_gd_Flush}, + {g2_Plot,g2_gd_Plot}, + {g2_Line,g2_gd_Line}, + /* {g2_PolyLine,g2_gd_PolyLine}, */ + {g2_Rectangle,g2_gd_Rectangle}, + {g2_FilledRectangle,g2_gd_FilledRectangle}, + /* {g2_Polygon,g2_gd_Polygon}, */ + {g2_FilledPolygon,g2_gd_FilledPolygon}, + /* {g2_Circle,g2_gd_Circle}, */ + /* {g2_FilledCircle,g2_gd_FilledCircle}, */ + /* {g2_Ellipse,g2_gd_Ellipse}, */ + /* {g2_FilledEllipse,g2_gd_FilledEllipse}, */ + /* {g2_Arc,g2_gd_Arc}, */ + /* {g2_FilledArc,g2_gd_FilledArc}, */ + {g2_String,g2_gd_DrawString}, + {g2_FUNIX_NULL, NULL}}; + + +#endif /* _g2_GD_TOKEN_FUN_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Repository new file mode 100755 index 00000000..9642f162 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/PS/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Entries new file mode 100755 index 00000000..430df523 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Entries @@ -0,0 +1,6 @@ +D/CVS//// +/g2_PS.c/1.1/Tue Feb 22 21:34:22 2005// +/g2_PS.h/1.1/Tue Mar 23 23:50:40 2004// +/g2_PS_P.h/1.1/Sun Feb 29 23:47:46 2004// +/g2_PS_definitions.h/1.1/Tue Apr 17 20:16:38 2001// +/g2_PS_funix.h/1.1/Tue Apr 17 20:16:38 2001// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Repository new file mode 100755 index 00000000..75622b0a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/PS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.c new file mode 100755 index 00000000..2e3388ea --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.c @@ -0,0 +1,624 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include +#include +#include +#include + +#include "g2.h" +#include "g2_device.h" +#include "g2_util.h" +#include "g2_config.h" + +#include "g2_PS.h" +#include "g2_PS_P.h" +#include "g2_PS_funix.h" +#include "g2_PS_definitions.h" + +static int N_PS=0; +static g2_PS_device *g2_PS_dev=NULL; + +/** + * \ingroup physdev + * \defgroup PS PostScript + */ + + +/* + * + * Attach generic PS device + * + */ +G2L int g2_open_PS_generic(const char *file_name, + enum g2_PS_paper paper, + enum g2_PS_orientation orientation, + enum g2_PS_format format, + long width, + long height) +{ + g2_PS_device *psout=NULL; + int pid=-1, i; + int vid; + FILE *fp; + + if((fp=fopen(file_name, "w"))==NULL) { + fprintf(stderr, "g2_attach_PS: Error! Can not open file '%s'\n", + file_name); + return -1; + } + + if(g2_PS_dev==NULL) { + g2_PS_dev=g2_malloc(sizeof(g2_PS_device)); + N_PS=1; /* first PS device */ + psout=&g2_PS_dev[N_PS-1]; + pid=0; + } else { + for(i=0;ifp=fp; /* init PostScript structures */ + psout->paper=paper; + psout->orient=orientation; + psout->format=format; + psout->width=width; + psout->height=height; + psout->inks=NULL; + psout->N_ink=0; + psout->pen=0; + psout->page_counter=0; + psout->bbox = 0; + + g2_PS_write_file_header(psout); + + g2_PS_set_line_width(pid, NULL, 0.0); + g2_PS_set_font_size(pid, NULL, 12.0); + + /* g2 settings */ + g2_allocate_basic_colors(vid); + g2_pen(vid, 1); + + return vid; +} + + +/** + * + * Create a PS device. + * + * \param file_name postscript file name + * \param paper paper type, see ::g2_PS_paper and \ref appendix Appendix + * \param orientation paper orientation, see ::g2_PS_orientation + * + * \return physical device id + * + * \ingroup PS + */ +G2L int g2_open_PS(const char *file_name, + enum g2_PS_paper paper, + enum g2_PS_orientation orientation) +{ + return g2_open_PS_generic(file_name,paper,orientation,g2_PS_PostScript,0,0); +} + + +/** + * + * Create an encapsulated PS device. + * + * \param file_name postscript file name + * + * \return physical device id + * + * \ingroup PS + */ +G2L int g2_open_EPSF(const char *file_name) +{ + return g2_open_PS_generic(file_name,0,0,g2_PS_EPSF,0,0); +} + + +/** + * + * Create an encapsulated PS device with clipping. + * + * \param file_name postscript file name + * \param width clipping region width + * \param height clipping region height + * + * \return physical device id + * + * \ingroup PS + */ +G2L int g2_open_EPSF_CLIP(const char *file_name, + long width, long height) +{ + return g2_open_PS_generic(file_name,0,0,g2_PS_EPSF_CLIP,width,height); +} + +/* + * + * Write header for postscript file + * + */ +int g2_PS_write_file_header(g2_PS_device *ps) +{ + int i; + if (ps->format == g2_PS_PostScript) + { + fprintf(ps->fp,"%%!PS-Adobe-2.0\n"); + switch(ps->orient) + { + case g2_PS_land: + fprintf(ps->fp,"%%%%Orientation: Landscape\n"); + break; + case g2_PS_port: + fprintf(ps->fp,"%%%%Orientation: Portrait\n"); + break; + } + } + else if (ps->format == g2_PS_EPSF_CLIP) + { + fprintf(ps->fp,"%%!PS-Adobe-3.0 EPSF-2.0\n"); + fprintf(ps->fp,"%%%%BoundingBox: 0 0 %ld %ld\n",ps->width,ps->height); + } + else if (ps->format == g2_PS_EPSF) + { + fprintf(ps->fp,"%%!PS-Adobe-3.0 EPSF-2.0\n"); + fprintf(ps->fp,"%%%%BoundingBox: (atend)\n"); + } + + fprintf(ps->fp,"%%%%Creator: g2 %s\n", G2_VERSION); + fprintf(ps->fp, "%%%%EndComments\n"); + + if (ps->format == g2_PS_EPSF_CLIP) + { + fprintf(ps->fp,"0 0 moveto\n"); + fprintf(ps->fp,"0 %ld rlineto\n",ps->height); + fprintf(ps->fp,"%ld 0 rlineto\n",ps->width); + fprintf(ps->fp,"0 %ld rlineto\n",-ps->height); + fprintf(ps->fp,"closepath\n"); + fprintf(ps->fp,"clip\n"); + } + + for(i=0;g2_PS_operators[i]!=NULL;i++) + fputs(g2_PS_operators[i], ps->fp); + + fprintf(ps->fp,"newpath\n"); + if((ps->orient==g2_PS_land) && (ps->format == g2_PS_PostScript)) + fprintf(ps->fp,"%d 0 translate 90 rotate\n", + g2_PS_paper_size[ps->paper][0]); + + fputs("%%PageTrailer\n%%Page: 1 1\n", ps->fp); + + return 0; +} + +/* + * + * Add circle at (x,y) of dimension size to bounding box + * + */ +void g2_PS_bbox_add(g2_PS_device *ps,double x,double y,double size) + { + if (ps->bbox == 0) /* bbox is empty */ + { + ps->x1=x-size; + ps->x2=x+size; + ps->y1=y-size; + ps->y2=y+size; + ps->bbox=1; + return; + } + + if (ps->x1 > x-size) + ps->x1=x-size; + else if (ps->x2 < x+size) + ps->x2=x+size; + + if (ps->y1 > y-size) + ps->y1=y-size; + else if (ps->y2 < y+size) + ps->y2=y+size; + return; + } + +/* + * + * Delete PS device + * + */ +int g2_PS_delete(int pid, void *pdp) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"\nshowpage\n"); + fprintf(ps->fp,"%%%%PageTrailer\n"); + fprintf(ps->fp,"%%%%EndPage\n"); + fprintf(ps->fp,"%%%%Trailer\n"); + if (ps->format == g2_PS_EPSF) + { + fprintf(ps->fp,"%%%%BoundingBox: %d %d %d %d\n", + (int)floor(ps->x1),(int)floor(ps->y1), + (int)ceil(ps->x2),(int)ceil(ps->y2)); + } + fprintf(ps->fp,"%%%%EOF\n"); + fclose(ps->fp); + free(ps->inks); + + ps->fp=NULL; /* free place */ + + return 0; +} + + + +int g2_PS_ink(int pid, void *pdp, + double red, double green, double blue) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + ps->N_ink++; + if(ps->inks==NULL) + ps->inks=(g2_PS_inks *)g2_malloc(ps->N_ink* + sizeof(g2_PS_inks)); + else + ps->inks=(g2_PS_inks *)g2_realloc((void *)ps->inks, + ps->N_ink* + sizeof(g2_PS_inks)); + + ps->inks[ps->N_ink-1].r=red; + ps->inks[ps->N_ink-1].g=green; + ps->inks[ps->N_ink-1].b=blue; + + return ps->N_ink-1; +} + + + +int g2_PS_pen(int pid, void *pdp, int color) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + if(color>=ps->N_ink || color<0) + return -1; + fprintf(ps->fp,"%.4g %.4g %.4g setrgbcolor\n", + (double)ps->inks[color].r, + (double)ps->inks[color].g, + (double)ps->inks[color].b); + ps->pen=color; + return 0; +} + + + +int g2_PS_set_background(int pid, void *pdp, int color) +{ + return 0; +} + + + +int g2_PS_clear_palette(int pid, void *pdp) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + free((void *)ps->inks); + ps->N_ink=0; + ps->inks=NULL; + return 0; +} + + + +int g2_PS_set_line_width(int pid, void *pdp, double w) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g setlinewidth\n", w); + ps->w = w; + return 0; +} + + + +int g2_PS_set_dash(int pid, void *pdp, int N, double *data) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + int i; + fprintf(ps->fp, "[ "); + for(i=0;i0.0) + fprintf(ps->fp, "%.4g ", data[i]); + fprintf(ps->fp, "] 0 setdash\n"); + return 0; +} + + + +int g2_PS_set_font_size(int pid, void *pdp, double size) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + if(size<=0.0) + return -1; + fprintf(ps->fp,"%s findfont %.4g scalefont setfont\n", g2_PSFont, size); + ps->size = size; + return 0; +} + + + +int g2_PS_clear(int pid, void *pdp) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp, "gsave showpage\n"); + fprintf(ps->fp, "%%%%PageTrailer\n%%%%EndPage\n"); + fprintf(ps->fp, "%%%%Page: %d %d\ngrestore newpath\n", + ps->page_counter+1, ps->page_counter+1); + ps->page_counter++; + return 0; +} + + + +int g2_PS_flush(int pid, void *pdp) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fflush(ps->fp); + return 0; +} + + + +int g2_PS_plot(int pid, void *pdp, double x, double y) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g P\n", x, y); + g2_PS_bbox_add(ps,x,y,1); + return 0; +} + + + +int g2_PS_line(int pid, void *pdp, double x1, double y1, double x2, double y2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g M %.4g %.4g L St\n", + x1, y1, x2, y2); + g2_PS_bbox_add(ps,x1,y1,ps->w); + g2_PS_bbox_add(ps,x2,y2,ps->w); + return 0; +} + + + +int g2_PS_poly_line(int pid, void *pdp, int N, double *points) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + int i; + fprintf(ps->fp,"%.4g %.4g M\n", points[0], points[1]); + g2_PS_bbox_add(ps,points[0], points[1],ps->w); + for(i=2;i<2*N;i+=2) + { + fprintf(ps->fp, "%.4g %.4g L\n", points[i], points[i+1]); + g2_PS_bbox_add(ps,points[i], points[i+1],ps->w); + } + fprintf(ps->fp, "St\n"); + return 0; +} + + + +int g2_PS_polygon(int pid, void *pdp, int N, double *points) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + int i; + fprintf(ps->fp,"%.4g %.4g M\n",points[0], points[1]); + g2_PS_bbox_add(ps,points[0], points[1],ps->w); + for(i=2;i<2*N;i+=2) + { + fprintf(ps->fp, "%.4g %.4g L\n", points[i], points[i+1]); + g2_PS_bbox_add(ps,points[i], points[i+1],ps->w); + } + fprintf(ps->fp, "%.4g %.4g L St\n", points[0], points[1]); + return 0; +} + + + +int g2_PS_filled_polygon(int pid, void *pdp, int N, double *points) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + int i; + fprintf(ps->fp,"newpath %.4g %.4g M\n",points[0], points[1]); + g2_PS_bbox_add(ps,points[0], points[1],ps->w); + for(i=2;i<2*N;i+=2) + { + fprintf(ps->fp, "%.4g %.4g L\n", points[i], points[i+1]); + g2_PS_bbox_add(ps,points[i], points[i+1],ps->w); + } + fprintf(ps->fp, "%.4g %.4g L fill St\n", points[0], points[1]); + return 0; +} + + + +int g2_PS_rectangle(int pid, void *pdp, + double x1, double y1, double x2, double y2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g %.4g %.4g R\n", + x2, y2, x1, y1); + g2_PS_bbox_add(ps,x1,y1,ps->w); + g2_PS_bbox_add(ps,x2,y2,ps->w); + return 0; +} + + + +int g2_PS_filled_rectangle(int pid, void *pdp, + double x1, double y1, double x2, double y2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g %.4g %.4g FR\n", + x2, y2, x1, y1); + g2_PS_bbox_add(ps,x1,y1,ps->w); + g2_PS_bbox_add(ps,x2,y2,ps->w); + return 0; +} + + + +int g2_PS_triangle(int pid, void *pdp, + double x1, double y1, + double x2, double y2, + double x3, double y3) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g %.4g %.4g %.4g %.4g T\n", + x1,y1,x2,y2,x3,y3); + g2_PS_bbox_add(ps,x1,y1,ps->w); + g2_PS_bbox_add(ps,x2,y2,ps->w); + g2_PS_bbox_add(ps,x3,y3,ps->w); + return 0; +} + + +int g2_PS_filled_triangle(int pid, void *pdp, + double x1, double y1, + double x2, double y2, + double x3, double y3) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"%.4g %.4g %.4g %.4g %.4g %.4g FT\n", + x1,y1,x2,y2,x3,y3); + g2_PS_bbox_add(ps,x1,y1,ps->w); + g2_PS_bbox_add(ps,x2,y2,ps->w); + g2_PS_bbox_add(ps,x3,y3,ps->w); + return 0; +} + + + +int g2_PS_arc(int pid, void *pdp, + double x, double y, + double r1, double r2, + double a1, double a2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + if(a1==a2) { + a1=0; + a2=360; + } + fprintf(ps->fp,"%.4g %.4g %.4g %.4g %.4g %.4g A\n", + a1, a2, r1, r2, x, y); + g2_PS_bbox_add(ps,x+r1,y+r2,ps->w); + g2_PS_bbox_add(ps,x-r1,y-r2,ps->w); + return 0; +} + + + +int g2_PS_filled_arc(int pid, void *pdp, + double x, double y, + double r1, double r2, + double a1, double a2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + if(a1==a2) { + a1=0; + a2=360; + } + fprintf(ps->fp,"%.4g %.4g %.4g %.4g %.4g %.4g FA\n", + a1, a2, r1, r2, x, y); + g2_PS_bbox_add(ps,x+r1,y+r2,ps->w); + g2_PS_bbox_add(ps,x-r1,y-r2,ps->w); + return 0; +} + + + +int g2_PS_ellipse(int pid, void *pdp, + double x, double y, + double r1, double r2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"0 360 %.4g %.4g %.4g %.4g A\n", + r1, r2, x, y); + g2_PS_bbox_add(ps,x+r1,y+r2,ps->w); + g2_PS_bbox_add(ps,x-r1,y-r2,ps->w); + return 0; +} + + + + +int g2_PS_filled_ellipse(int pid, void *pdp, + double x, double y, + double r1, double r2) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fprintf(ps->fp,"0 360 %.4g %.4g %.4g %.4g FA\n", + r1, r2, x, y); + g2_PS_bbox_add(ps,x+r1,y+r2,ps->w); + g2_PS_bbox_add(ps,x-r1,y-r2,ps->w); + return 0; +} + + + +int g2_PS_draw_string(int pid, void *pdp, + double x, double y, const char *text) +{ + g2_PS_device *ps=&g2_PS_dev[pid]; + fputc('(', ps->fp); + for(;*text!='\0';text++) + switch(*text) { + case '(': + fputs("\\(", ps->fp); + break; + case ')': + fputs("\\)", ps->fp); + break; + case '\\': + fputs("\\\\", ps->fp); + break; + default: + fputc(*text, ps->fp); + break; + } + fprintf(ps->fp,") %.4g %.4g S\n", x, y); + g2_PS_bbox_add(ps,x,y,ps->size); + g2_PS_bbox_add(ps,x+ps->size*strlen(text),y,ps->size); + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.h new file mode 100755 index 00000000..88eb918c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.h @@ -0,0 +1,118 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_PS_H +#define _G2_PS_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + +/** + * g2 paper type. + * + * \ingroup PS + */ +enum g2_PS_paper { /* Name Size(Pt) */ + g2_A0, /**< A0 2384 x 3370 */ + g2_A1, /**< A1 1684 x 2384 */ + g2_A2, /**< A2 1191 x 1684 */ + g2_A3, /**< A3 842 x 1191 */ + g2_A4, /**< A4 595 x 842 */ + g2_A5, /**< A5 420 x 595 */ + g2_A6, /**< A6 297 x 420 */ + g2_A7, /**< A7 210 x 297 */ + g2_A8, /**< A8 148 x 210 */ + g2_A9, /**< A9 105 x 148 */ + g2_B0, /**< B0 2920 x 4127 */ + g2_B1, /**< B1 2064 x 2920 */ + g2_B2, /**< B2 1460 x 2064 */ + g2_B3, /**< B3 1032 x 1460 */ + g2_B4, /**< B4 729 x 1032 */ + g2_B5, /**< B5 516 x 729 */ + g2_B6, /**< B6 363 x 516 */ + g2_B7, /**< B7 258 x 363 */ + g2_B8, /**< B8 181 x 258 */ + g2_B9, /**< B9 127 x 181 */ + g2_B10, /**< B10 91 x 127 */ + g2_Comm_10_Envelope, /**< Comm #10 Envelope 297 x 684 */ + g2_C5_Envelope, /**< C5 Envelope 461 x 648 */ + g2_DL_Envelope, /**< DL Envelope 312 x 624 */ + g2_Folio, /**< Folio 595 x 935 */ + g2_Executive, /**< Executive 522 x 756 */ + g2_Letter, /**< Letter 612 x 792 */ + g2_Legal, /**< Legal 612 x 1008 */ + g2_Ledger, /**< Ledger 1224 x 792 */ + g2_Tabloid /**< Tabloid 792 x 1224 */ +}; + + +/** + * g2 paper orientation. + * + * \ingroup PS + */ +enum g2_PS_orientation { + g2_PS_land, /**< landscape */ + g2_PS_port /**< portrait */ +}; + +/* + * g2 Format + */ +enum g2_PS_format { + g2_PS_PostScript, /* PostScript */ + g2_PS_EPSF, /* EPSF format */ + g2_PS_EPSF_CLIP /* EPSF format with predefined Bounding Box*/ +}; + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + + +G2L int g2_open_PS(const char *file_name, + enum g2_PS_paper paper, + enum g2_PS_orientation orientation); + +G2L int g2_open_EPSF(const char *file_name); + +G2L int g2_open_EPSF_CLIP(const char *file_name, + long width, long height); + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_PS_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/PS/g2_PS.o new file mode 100755 index 0000000000000000000000000000000000000000..b49f126a5cc6ca9caabebd8ea4e5a56964348da5 GIT binary patch literal 26616 zcmd6P4SbZ}pdlm>6#{A?B!CSX2_W)e%*Q08giM@F0PANP 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Definitions */ +int g2_win32_registered = FALSE; +HINSTANCE g2res_DLL; /* Instance of the resource DLL */ + +#define PDP ((struct g2_win32_STRUCT *)pdp) + +#ifndef PI +#define PI 3.14159265358979323846 +#endif /* PI */ + +#define sgn(x) (x>0?1:x?-1:0) + +/* someday their might be a DLL version of g2 */ +#ifdef G2DLL +BOOL WINAPI DllMain( HANDLE hModule, DWORD fdwreason, LPVOID lpReserved ) +{ + switch(fdwreason) { + case DLL_PROCESS_ATTACH: + // The DLL is being mapped into process's address space + // Do any required initialization on a per application basis, return FALSE if failed + MessageBox(NULL, "DLL Process Attach", "DLL Message 1", MB_OK); + break; + case DLL_THREAD_ATTACH: + // A thread is created. Do any required initialization on a per thread basis + MessageBox(NULL, "DLL Thread Attach", "DLL Message 1", MB_OK); + break; + case DLL_THREAD_DETACH: + // Thread exits with cleanup + MessageBox(NULL, "DLL Thread Detach", "DLL Message 1", MB_OK); + break; + case DLL_PROCESS_DETACH: + // The DLL unmapped from process's address space. Do necessary cleanup + MessageBox(NULL, "DLL Process Detach", "DLL Message 1", MB_OK); + break; + default: + MessageBox(NULL, "DLL default", "DLL Message 1", MB_OK); + + } + return TRUE; +} +#endif + + +g2_win32_SetPen(int pid, void *pdp) + { + HGDIOBJ oldpen; + LOGBRUSH logBrush ; + logBrush.lbStyle = PS_SOLID; + logBrush.lbColor = PDP->Inks[PDP->Pen]; + logBrush.lbHatch = 0 ; + + oldpen = PDP->hPen; + PDP->hPen = ExtCreatePen (logBrush.lbStyle | PS_GEOMETRIC | + PS_ENDCAP_FLAT | PS_JOIN_BEVEL | (PDP->PenStyle > 0)*PS_USERSTYLE, + PDP->PenWidth, &logBrush, + PDP->PenStyle , PDP->PenDash) ; + if (PDP->hPen != NULL) + { + SelectObject(PDP->hMemDC,PDP->hPen); +/* if (PDP->type == g2_win32)*/ + DeleteObject(oldpen); + } + else + { + errhandler("Pen",NULL); + PDP->hPen = oldpen; + } + + oldpen = PDP->hNullPen; + PDP->hNullPen = CreatePen(PS_SOLID,1,PDP->Inks[PDP->Pen]); + if (PDP->hNullPen != NULL) + { +/* if (PDP->type == g2_win32)*/ + DeleteObject(oldpen); + } + else + { + errhandler("Pen",NULL); + PDP->hNullPen = oldpen; + } + + return 0; + } + + +int g2_win32_Cleanup(int pid, void *pdp) + { + struct g2_win32_STRUCT *thispdp; + + thispdp = pdp; + g2_win32_ClearPalette(pid,pdp); + if (PDP->hBrush != NULL) DeleteObject(PDP->hBrush); + if (PDP->hPen != NULL) DeleteObject(PDP->hPen); + if (PDP->hNullPen != NULL) DeleteObject(PDP->hPen); + if (PDP->hFont != NULL) DeleteObject(PDP->hFont); + if (PDP->hBitmap != NULL) DeleteObject(PDP->hBitmap); + if (PDP->hMemDC != NULL) DeleteDC(PDP->hMemDC); + if (PDP->PenDash != NULL) free(PDP->PenDash); + free(thispdp); + return 0; + } + + + +int g2_win32_Delete(int pid, void *pdp) + { + switch(PDP->type) + { + case g2_win32: + SendMessage(PDP->hwndThreadWindow,WM_CLOSE,(WPARAM)NULL,(LPARAM)NULL); + break; + case g2_wmf32: + { + CloseEnhMetaFile(PDP->hMemDC); + g2_win32_Cleanup(pid,pdp); + break; + } + } + return 0; + } + + +int g2_win32_Clear(int pid, void *pdp) + { + int OldPen; + + OldPen = PDP->Pen; + g2_win32_Pen(pid,pdp,PDP->BkColor); + g2_win32_FilledRectangle(pid,pdp,0,0,PDP->nWidth,PDP->nHeight); + g2_win32_Pen(pid,pdp,OldPen); + return 0; + } + +int g2_win32_Flush(int pid, void *pdp) + { + InvalidateRect(PDP->hwndThreadWindow, (RECT *)NULL, TRUE); + return 0; + } + +int g2_win32_Pen(int pid, void *pdp, int color) + { + struct tagLOGBRUSH logbrush; + HGDIOBJ oldbrush; + + if(color>=PDP->NoOfInks || color<0) + { + fprintf(stderr,"g2_WIN32: Ink %d not defined\n",color); + return -1; + } + + PDP->Pen = color; + PDP->PenColor = PDP->Inks[color]; + g2_win32_SetPen(pid,pdp); + + logbrush.lbStyle = BS_SOLID; + logbrush.lbColor = PDP->PenColor; + oldbrush = PDP->hBrush; + PDP->hBrush = CreateBrushIndirect(&logbrush); + if (PDP->hBrush == NULL) + { + errhandler("Pen (CreateBrush)",NULL); + PDP->hBrush = oldbrush; + } + else +/* if (PDP->type == g2_win32)*/ + DeleteObject(oldbrush); + return 0; + } + +int g2_win32_Ink(int pid, void *pdp, double red, double green, double blue) + { + BYTE rc,gc,bc; + + rc = (BYTE)((int)(red*255)); + gc = (BYTE)((int)(green*255)); + bc = (BYTE)((int)(blue*255)); + + PDP->NoOfInks++; + + if(PDP->Inks==NULL) + PDP->Inks=(COLORREF *)malloc(PDP->NoOfInks*sizeof(COLORREF)); + else + PDP->Inks=(COLORREF *)realloc((void *)PDP->Inks,PDP->NoOfInks*sizeof(COLORREF)); + + if(PDP->Inks==NULL) + { + fputs("g2: not enough memory\n",stderr); + return -1; + } + + PDP->Inks[PDP->NoOfInks-1]=RGB(rc,gc,bc); + return PDP->NoOfInks-1; + } + + +int g2_win32_ClearPalette(int pid, void *pdp) + { + if (PDP->Inks != NULL) + free(PDP->Inks); + PDP->Inks = NULL; + PDP->NoOfInks = 0; + return 0; + } + + +int g2_win32_SetBackground(int pid, void *pdp, int color) + { + PDP->BkColor = color; + SetBkColor(PDP->hMemDC,PDP->BkColor); + return 0; + } + +int g2_win32_SetLineWidth(int pid, void *pdp, int w) + { + PDP->PenWidth = w; + g2_win32_SetPen(pid,pdp); + return 0; + } + +int g2_win32_SetDash(int pid, void *pdp, int n, int *data) + { + if (PDP->PenDash != NULL) + free(PDP->PenDash); + PDP->PenDash = NULL; + PDP->PenStyle = n; + if (n > 0) + { + int i; + PDP->PenDash = (DWORD *)malloc(n*sizeof(DWORD)); + for (i=0;iPenDash[i] = data[i]; + } + g2_win32_SetPen(pid,pdp); + return 0; + } + + +int g2_win32_SetFontSize(int pid, void *pdp, int size) + { + //static LOGFONT lf = {10,0,0,0,0,0,0,0,0,0,0,0,0,"Arial\0"}; + HGDIOBJ oldfont; + + oldfont = PDP->hFont; + //lf.lfHeight = size; + //PDP->hFont = CreateFontIndirect(&lf); + PDP->hFont = CreateFont(-size, 0, 0, 0, FW_NORMAL, 0, 0, 0, 0, OUT_TT_ONLY_PRECIS , 0, PROOF_QUALITY,0, "Times New Roman\0"); + if (PDP->hFont == NULL) + { + errhandler("Font (CreateFont)",NULL); + PDP->hFont = oldfont; + } + else + { + SelectObject(PDP->hMemDC,PDP->hFont); + if (oldfont != NULL)// && PDP->type == g2_win32) + DeleteObject(oldfont); + } + return 0; + } + +int g2_win32_Plot(int pid, void *pdp, int x, int y) + { + return SetPixel(PDP->hMemDC,x,y,PDP->PenColor); + } + +int g2_win32_Line(int pid, void *pdp, int x1, int y1, int x2, int y2) + { + MoveToEx(PDP->hMemDC,x1,y1,NULL); + LineTo(PDP->hMemDC,x2,y2); + SetPixel(PDP->hMemDC,x1,y1,PDP->PenColor); + SetPixel(PDP->hMemDC,x2,y2,PDP->PenColor); + // specifically draw end points since windows does not include one endpoint + return 0; + } + +int g2_win32_PolyLine(int pid, void *pdp, int N, int *points) + { + POINT *PointList; + int i; + + PointList = (POINT *)malloc(N*sizeof(POINT)); + if (PointList == NULL) + { + fprintf(stderr,"g2_win32: not enough memory !\n"); + return -1; + } + for (i=0;ihMemDC,PointList,N); + free(PointList); + return 0; + } + + + +int g2_win32_Rectangle(int pid, void *pdp, int x, int y, int x2, int y2) + { + SelectObject(PDP->hMemDC,GetStockObject(NULL_BRUSH)); + Rectangle(PDP->hMemDC,x,y,x2+1,y2+1); // add one since windows excludes lower right point + return 0; + } + +int g2_win32_FilledRectangle(int pid, void *pdp, int x1, int y1, int x2, int y2) + { + SelectObject(PDP->hMemDC,PDP->hBrush); + SelectObject(PDP->hMemDC,PDP->hNullPen); + return Rectangle(PDP->hMemDC,x1,y1,x2+1,y2+1); // add one since windows excludes lower right point + SelectObject(PDP->hMemDC,PDP->hPen); + return 0; + } + +int g2_win32_Polygon(int pid, void *pdp, int N, int *points) + { + POINT *PointList; + int i; + PointList = (POINT *)malloc(N*sizeof(POINT)); + if (PointList == NULL) + { + fprintf(stderr,"g2: not enough memory !\n"); + return -1; + } + for (i=0;ihMemDC,GetStockObject(NULL_BRUSH)); + Polygon(PDP->hMemDC,PointList,N); + free(PointList); + return 0; + } + +int g2_win32_FilledPolygon(int pid, void *pdp, int N, int *points) + { + POINT *PointList; + int i; + PointList = (POINT *)malloc(N*sizeof(POINT)); + if (PointList == NULL) + { + fprintf(stderr,"g2: not enough memory !\n"); + return -1; + } + for (i=0;ihMemDC,PDP->hBrush); + SelectObject(PDP->hMemDC,PDP->hNullPen); + Polygon(PDP->hMemDC,PointList,N); + SelectObject(PDP->hMemDC,PDP->hPen); + free(PointList); + return 0; + } + +int g2_win32_Ellipse(int pid, void *pdp, int x, int y, int r1, int r2) + { + SelectObject(PDP->hMemDC,GetStockObject(NULL_BRUSH)); + return Ellipse(PDP->hMemDC,x-r1,y-r2,x+r1+1,y+r2+1); // add one since windows is end exclusive + } + +int g2_win32_FilledEllipse(int pid, void *pdp, int x, int y, int r1, int r2) + { + SelectObject(PDP->hMemDC,PDP->hBrush); + SelectObject(PDP->hMemDC,PDP->hNullPen); + return Ellipse(PDP->hMemDC,x-r1,y-r2,x+r1+1,y+r2+1); // add one since windows is end exclusive + SelectObject(PDP->hMemDC,PDP->hPen); + return 0; + } + +int g2_win32_Arc(int pid, void *pdp, int x, int y, int r1, int r2, double a1, double a2) + { + a1 *= PI/180.; + a2 *= PI/180.; + SelectObject(PDP->hMemDC,GetStockObject(NULL_BRUSH)); + if (PDP->type == g2_win32) + return Arc(PDP->hMemDC,x-r1,y-r2,x+r1,y+r2,dtoi(x+r1*cos(a1)),dtoi(y-r2*sin(a1)),dtoi(x+r1*cos(a2)),dtoi(y-r2*sin(a2))); + else + return Arc(PDP->hMemDC,x-r1,y-r2,x+r1,y+r2,dtoi(x+r1*cos(a2)),dtoi(y-r2*sin(a2)),dtoi(x+r1*cos(a1)),dtoi(y-r2*sin(a1))); + } + +int g2_win32_FilledArc(int pid, void *pdp, int x, int y, int r1, int r2, double a1, double a2) + { + a1 *= PI/180.; + a2 *= PI/180.; + SelectObject(PDP->hMemDC,PDP->hBrush); + SelectObject(PDP->hMemDC,PDP->hNullPen); + if (PDP->type == g2_win32) + Pie(PDP->hMemDC,x-r1,y-r2,x+r1,y+r2,dtoi(x+r1*cos(a1)),dtoi(y-r2*sin(a1)),dtoi(x+r1*cos(a2)),dtoi(y-r2*sin(a2))); + else + Pie(PDP->hMemDC,x-r1,y-r2,x+r1,y+r2,dtoi(x+r1*cos(a2)),dtoi(y-r2*sin(a2)),dtoi(x+r1*cos(a1)),dtoi(y-r2*sin(a1))); + SelectObject(PDP->hMemDC,PDP->hPen); + return 0; + } + +int g2_win32_DrawString(int pid, void *pdp, int x, int y, const char *text) + { + SetTextColor(PDP->hMemDC,PDP->PenColor); + SetBkMode(PDP->hMemDC,TRANSPARENT); + return TextOut(PDP->hMemDC,x,y,text,strlen(text)); + } + +int g2_win32_QueryPointer(int pid, void *pdp, int *x, int *y, unsigned int *button) +// +// Thanks to input by Martin stéphane +// + { + POINT point; + + GetCursorPos(&point); + + ScreenToClient(PDP->hwndThreadWindow,&point); + + *y=point.y; + *x=point.x; + *button=0; + + if (PDP->hwndThreadWindow != GetForegroundWindow()) + return; // return if our window does not have the focus + + if (GetKeyState(VK_LBUTTON)<0) + *button=*button+256; + + if (GetKeyState(VK_MBUTTON)<0) + *button=*button+512; + + if (GetKeyState(VK_RBUTTON)<0) + *button=*button+1024; + + return 0; + } + +void errhandler(LPSTR errtxt,HWND hwnd) +{ + LPVOID lpMessageBuffer; + char szError[255]; + DWORD LastError; + + LastError = GetLastError(); + + FormatMessage(FORMAT_MESSAGE_ALLOCATE_BUFFER |FORMAT_MESSAGE_FROM_SYSTEM, + NULL,LastError,MAKELANGID(LANG_NEUTRAL, SUBLANG_DEFAULT), //The user default language + (LPTSTR) &lpMessageBuffer,0,NULL ); + + sprintf(szError,"Error in %s\n Error code %d : %s\n" ,errtxt,LastError,lpMessageBuffer); + MessageBox(hwnd,szError,"error",MB_OK); + + LocalFree( lpMessageBuffer ); +} + + +int InitApplication() +{ + WNDCLASS wc; + + // Fill in window class structure with parameters that describe the + // main window. + + g2res_DLL = LoadLibrary("g2res.dll"); + + if (g2res_DLL == NULL) + printf("Warning: Could not load g2 resource DLL\n Menu and Icon are disabled\n"); + + + wc.style = CS_HREDRAW | CS_VREDRAW; // Class style(s). + wc.lpfnWndProc = g2_WndProc; // Function to retrieve messages for windows of this class. + wc.cbClsExtra = 0; // No per-class extra data. + wc.cbWndExtra = 0; // No per-window extra data. + wc.hInstance = 0; // Application that owns the class. + wc.hIcon = NULL; + if (g2res_DLL != NULL) + { + wc.hIcon = LoadIcon(g2res_DLL, MAKEINTRESOURCE(IDI_ICON1)); + if (wc.hIcon == NULL) + errhandler("Error in LoadIcon",NULL); + } + wc.hCursor = LoadCursor(NULL, IDC_ARROW); + wc.hbrBackground = NULL; + wc.lpszMenuName = "G2WIN32"; + wc.lpszClassName = "g2Window"; // Name used in call to CreateWindow. + + /* Register the window class and return success/failure code. */ + + + if(!RegisterClass(&wc)) + { + errhandler("RegisterClass",NULL); + return FALSE; + } + g2_win32_registered = TRUE; + return TRUE; +} + + +/** + * \ingroup physdev + * \defgroup win32 MS Windows + */ + +/** + * + * Create a Windows device. + * + * \param width window width + * \param height window height + * \param title window title + * \param type window type, see ::g2_win32_type + * + * \return physical device id + * + * \ingroup win32 + */ +int g2_open_win32(int width, int height, const char *title, int type) + { + int pid=0,vid; + long ThreadID; + + g2_win32_STRUCT *pdp; + + pdp = (g2_win32_STRUCT *)malloc(sizeof(g2_win32_STRUCT)); + + PDP->type = type; + PDP->NoOfInks = 0; + PDP->Inks = NULL; + PDP->PenStyle = 0; + PDP->PenWidth = 1; + PDP->PenColor = RGB(1,1,1); + PDP->PenDash = NULL; + PDP->nWidth = width; + PDP->nHeight = height; + PDP->messageloop = 0; + PDP->hFont = NULL; + + switch(type) { + case g2_win32: + { + if(g2_win32_registered == FALSE) + InitApplication(); + + PDP->x = 1; + PDP->y = 1; + if (title != NULL) + PDP->title = title; + else + PDP->title = "g2 Window"; + PDP->hThread = CreateThread(NULL, 0, + (LPTHREAD_START_ROUTINE)g2_StartThread, + (LPVOID)(pdp), + 0, + (LPDWORD) &ThreadID ); + + if (PDP->hThread == NULL) + fprintf(stderr,"g2_win32: Thread could not be started\n"); + + SetThreadPriority(PDP->hThread,THREAD_PRIORITY_ABOVE_NORMAL); + //Wait till window is created by Thread + while( PDP->messageloop == 0) + Sleep(10); + break; + } + case g2_wmf32 : + { + DWORD dwInchesX; + DWORD dwInchesY; + DWORD dwDPI = 72; + RECT Rect = { 0, 0, 0, 0 }; + TCHAR szDesc[] = "Created by g2\0\0"; + HDC hScreenDC; + float PixelsX, PixelsY, MMX, MMY; + + dwInchesX = PDP->nWidth/72; + dwInchesY = PDP->nHeight/72; + // dwInchesX x dwInchesY in .01mm units + SetRect( &Rect, 0, 0,dwInchesX*2540, dwInchesY*2540 ); + + // Get a Reference DC + hScreenDC = GetDC( NULL ); + + // Get the physical characteristics of the reference DC + PixelsX = (float)GetDeviceCaps( hScreenDC, HORZRES ); + PixelsY = (float)GetDeviceCaps( hScreenDC, VERTRES ); + MMX = (float)GetDeviceCaps( hScreenDC, HORZSIZE ); + MMY = (float)GetDeviceCaps( hScreenDC, VERTSIZE ); + + // Create the Metafile + PDP->hMemDC = CreateEnhMetaFile(hScreenDC, title, &Rect, szDesc); + //tstDC = CreateEnhMetaFile(hScreenDC, "test.emf", &Rect, szDesc); + + // Release the reference DC + ReleaseDC( NULL, hScreenDC ); + // Anisotropic mapping mode + SetMapMode( PDP->hMemDC, MM_ANISOTROPIC ); + // Set the Windows extent + SetWindowExtEx( PDP->hMemDC, dwInchesX*dwDPI, dwInchesY*dwDPI, NULL ); + + // Set the viewport extent to reflect + // dwInchesX" x dwInchesY" in device units + SetViewportExtEx( PDP->hMemDC, + (int)((float)dwInchesX*25.4f*PixelsX/MMX), + (int)((float)dwInchesY*25.4f*PixelsY/MMY), + NULL ); +// printf("viewport: %d %d\n",(int)((float)dwInchesX*25.4f*PixelsX/MMX), +// (int)((float)dwInchesY*25.4f*PixelsY/MMY)); + // create the device context +// PDP->hMemDC = CreateMetaFile(NULL) ; + +// PDP->hMemDC = CreateEnhMetaFile( (HDC)NULL, title, &WmfRect, "Created by g2"); +// PDP->hMemDC = CreateMetaFile(title); +// SetMapMode(PDP->hMemDC,MM_LOMETRIC ); +// SetWindowExtEx(PDP->hMemDC,width,height,NULL); +// SetViewportExtEx(PDP->hMemDC,width*1000,height*1000,NULL); + if (PDP->hMemDC == NULL) errhandler("Could not Create Metafile !\n",NULL); + SetArcDirection(PDP->hMemDC,AD_CLOCKWISE); + break; + } + default: + return height; + } + SetTextAlign(PDP->hMemDC,TA_BOTTOM | TA_LEFT); + vid = g2_register_physical_device(pid, pdp, + g2_IntCoor, g2_win32_funix, + 1.0, -1.0, + 0.0, height-1); + + g2_allocate_basic_colors(vid); + g2_pen(vid,1); + g2_set_background(vid, 0); + g2_set_font_size(vid, 10); + g2_clear(vid); + + return vid; + } + +#undef PDP diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.h new file mode 100755 index 00000000..b35a05d3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.h @@ -0,0 +1,68 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +/* This is g2_win32.h */ +#ifndef _G2_WIN32_H +#define _G2_WIN32_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + +#include + +// Common Library header for DLL and application +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#define LINKDLL __declspec( dllexport) +#else +/* Use DLL */ +#define LINKDLL __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define LINKDLL +#endif +#else +/* Use non-win32 */ +#define LINKDLL +#endif + +/** + * Window type + * + * \ingroup win32 + */ +enum g2_win32_type { + g2_win32, /**< regular window */ + g2_wmf32 /**< windows meta file */ +}; + + +LINKDLL int g2_open_win32(int width, int height, const char *filename,int type); + + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + + +#endif /* _G2_WIN32_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.rc b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.rc new file mode 100755 index 00000000..ffa58aa5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32.rc @@ -0,0 +1,167 @@ +//Microsoft Developer Studio generated resource script. +// +#include "resource.h" + +#define APSTUDIO_READONLY_SYMBOLS +///////////////////////////////////////////////////////////////////////////// +// +// Generated from the TEXTINCLUDE 2 resource. +// +#include "afxres.h" + +///////////////////////////////////////////////////////////////////////////// +#undef APSTUDIO_READONLY_SYMBOLS + +///////////////////////////////////////////////////////////////////////////// +// English (U.S.) resources + +#if !defined(AFX_RESOURCE_DLL) || defined(AFX_TARG_ENU) +#ifdef _WIN32 +LANGUAGE LANG_ENGLISH, SUBLANG_ENGLISH_US +#pragma code_page(1252) +#endif //_WIN32 + +///////////////////////////////////////////////////////////////////////////// +// +// Icon +// + +// Icon with lowest ID value placed first to ensure application icon +// remains consistent on all systems. +IDI_ICON1 ICON DISCARDABLE "g2_Win32.ico" + +///////////////////////////////////////////////////////////////////////////// +// +// DESIGNINFO +// + +#ifdef APSTUDIO_INVOKED +GUIDELINES DESIGNINFO DISCARDABLE +BEGIN + "ABOUTBOX", DIALOG + BEGIN + LEFTMARGIN, 7 + RIGHTMARGIN, 156 + TOPMARGIN, 7 + BOTTOMMARGIN, 91 + END +END +#endif // APSTUDIO_INVOKED + + +#ifndef _MAC +///////////////////////////////////////////////////////////////////////////// +// +// Version +// + +VS_VERSION_INFO VERSIONINFO + FILEVERSION 1,0,0,1 + PRODUCTVERSION 1,0,0,1 + FILEFLAGSMASK 0x3fL +#ifdef _DEBUG + FILEFLAGS 0x1L +#else + FILEFLAGS 0x0L +#endif + FILEOS 0x40004L + FILETYPE 0x2L + FILESUBTYPE 0x0L +BEGIN + BLOCK "StringFileInfo" + BEGIN + BLOCK "040904b0" + BEGIN + VALUE "CompanyName", "\0" + VALUE "FileDescription", "g2_win32\0" + VALUE "FileVersion", "1, 0, 0, 1\0" + VALUE "InternalName", "g2_win32\0" + VALUE "LegalCopyright", "Copyright © 1996-1998\0" + VALUE "OriginalFilename", "g2_win32\0" + VALUE "ProductName", "g2_win32\0" + VALUE "ProductVersion", "1, 0, 0, 1\0" + END + END + BLOCK "VarFileInfo" + BEGIN + VALUE "Translation", 0x409, 1200 + END +END + +#endif // !_MAC + + +///////////////////////////////////////////////////////////////////////////// +// +// Dialog +// + +ABOUTBOX DIALOG DISCARDABLE 0, 0, 163, 98 +STYLE DS_MODALFRAME | WS_POPUP | WS_CAPTION | WS_SYSMENU +CAPTION "About g2" +FONT 8, "MS Sans Serif" +BEGIN + DEFPUSHBUTTON "OK",IDOK,55,71,50,14 + CTEXT "g2 version 0.40\n\n (c) 1998-1999\n Ljubomir Milanovic\nHorst Wagner", + IDC_STATIC,27,7,105,55 + ICON IDI_ICON1,IDC_STATIC,9,9,20,20 +END + + +#ifdef APSTUDIO_INVOKED +///////////////////////////////////////////////////////////////////////////// +// +// TEXTINCLUDE +// + +1 TEXTINCLUDE DISCARDABLE +BEGIN + "resource.h\0" +END + +2 TEXTINCLUDE DISCARDABLE +BEGIN + "#include ""afxres.h""\r\n" + "\0" +END + +3 TEXTINCLUDE DISCARDABLE +BEGIN + "\r\n" + "\0" +END + +#endif // APSTUDIO_INVOKED + + +///////////////////////////////////////////////////////////////////////////// +// +// Menu +// + +G2WIN32 MENU DISCARDABLE +BEGIN + POPUP "File" + BEGIN + MENUITEM "Copy", ID_FILE_COPY + MENUITEM "Close", ID_FILE_CLOS + MENUITEM SEPARATOR + MENUITEM "About", ID_FILE_ABOUT + END +END + +#endif // English (U.S.) resources +///////////////////////////////////////////////////////////////////////////// + + + +#ifndef APSTUDIO_INVOKED +///////////////////////////////////////////////////////////////////////////// +// +// Generated from the TEXTINCLUDE 3 resource. +// + + +///////////////////////////////////////////////////////////////////////////// +#endif // not APSTUDIO_INVOKED + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_P.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_P.h new file mode 100755 index 00000000..83d3437e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_P.h @@ -0,0 +1,119 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ + +#ifndef G2_WIN32_P_H +#define G2_WIN32_P_H + +#include "windows.h" +#include + +extern HMENU hmenu; +extern HANDLE ghModule; +extern HINSTANCE g2res_DLL; + +typedef struct g2_win32_STRUCT { + HANDLE hThread; + HWND hwndThreadWindow; + HANDLE hinst; + HBITMAP hBitmap; + HDC hMemDC; + HPEN hPen; + HPEN hNullPen; + HBRUSH hBrush; + HFONT hFont; + int nWidth; + int nHeight; + int x; + int y; + int NoOfInks; + int PenWidth; + int PenStyle; + DWORD *PenDash; + int Pen; + int BkColor; + COLORREF PenColor; + COLORREF *Inks; + char *title; + int type; + int messageloop; + } g2_win32_STRUCT; + + +BOOL SaveBitmapAs(HWND hWnd,struct XPGTHREADINFO *pThreadInfo); +LRESULT CALLBACK g2_WndProc(HWND hWnd, UINT message, WPARAM wParam, LPARAM lParam); +long WINAPI g2_StartThread(struct g2_win32_STRUCT *pdp); +void errhandler(LPSTR errtxt,HWND hwnd); + + +int g2_win32_init_win32(int pid, void *pdp, int vid, int width,int height); +int g2_win32_init_win32X(int pid, void *pdp, + int width, int height, + int xposition, int yposition, + char *windowname, char *iconname, + char *icondata, int iconwidth, int iconheight); +int g2_win32_Delete(int pid, void *pdp); +int g2_win32_Clear(int pid, void *pdp); +int g2_win32_Flush(int pid, void *pdp); +int g2_win32_Ink(int pid, void *pdp, + double red, double green, double blue); +int g2_win32_ClearPalette(int pid, void *pdp); +int g2_win32_ResetPalette(int pid, void *pdp); +int g2_win32_SetBackground(int pid, void *pdp, int color); +int g2_win32_Pen(int pid, void *pdp, int color); +int g2_win32_Paper(int pid, void *pdp, int color); +int g2_win32_SetLineWidth(int pid, void *pdp, int w); +int g2_win32_SetDash(int pid, void *pdp, int n, int *data); +int g2_win32_SetFontSize(int pid, void *pdp, int size); +int g2_win32_Plot(int pid, void *pdp, int x, int y); +int g2_win32_Line(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_win32_PolyLine(int pid, void *pdp, int N, int *p); +int g2_win32_Polygon(int pid, void *pdp, int N, int *p); +int g2_win32_FilledPolygon(int pid, void *pdp, int N, int *p); +int g2_win32_Triangle(int pid, void *pdp, + int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_win32_FilledTriangle(int pid, void *pdp, int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_win32_Rectangle(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_win32_FilledRectangle(int pid, void *pdp, + int x1, int y1, int x2, int y2); +int g2_win32_Circle(int pid, void *pdp, int x, int y, int r); +int g2_win32_FilledCircle(int pid, void *pdp, int x, int y, int r); +int g2_win32_Arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_win32_FilledArc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_win32_Ellipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_win32_FilledEllipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_win32_DrawString(int pid, void *pdp, int x, int y, const char *text); +int g2_win32_QueryPointer(int pid, void *pdp, int *x, int *y, unsigned int *button); + +int g2_win32_AllocateBasicColors(int pid, void *pdp); + +int g2_win32_Cleanup(int pid, void *pdp); + + +#endif /* g2_win32_P_H */ + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_funix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_funix.h new file mode 100755 index 00000000..84593b94 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_funix.h @@ -0,0 +1,56 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef G2_WIN32_FUNIX_H +#define G2_WIN32_FUNIX_H + +#include "g2_win32_P.h" +#include "g2_physical_device.h" + +const g2_funix_fun g2_win32_funix[] = { + { g2_Delete, g2_win32_Delete }, + { g2_Ink, g2_win32_Ink }, + { g2_Pen, g2_win32_Pen }, + { g2_SetBackground, g2_win32_SetBackground }, + { g2_ClearPalette, g2_win32_ClearPalette }, + { g2_SetLineWidth, g2_win32_SetLineWidth }, + { g2_SetDash, g2_win32_SetDash }, + { g2_SetFontSize, g2_win32_SetFontSize }, + { g2_Clear, g2_win32_Clear }, + { g2_Flush, g2_win32_Flush }, + { g2_Save, g2_win32_Flush }, + { g2_Plot, g2_win32_Plot }, + { g2_Line, g2_win32_Line }, + { g2_PolyLine, g2_win32_PolyLine }, + { g2_Polygon, g2_win32_Polygon }, + { g2_FilledPolygon, g2_win32_FilledPolygon }, + { g2_Rectangle, g2_win32_Rectangle }, + { g2_FilledRectangle, g2_win32_FilledRectangle }, + { g2_Arc, g2_win32_Arc }, + { g2_FilledArc, g2_win32_FilledArc }, + { g2_Ellipse, g2_win32_Ellipse }, + { g2_FilledEllipse, g2_win32_FilledEllipse }, + { g2_Circle, NULL }, + { g2_FilledCircle, NULL }, + { g2_String, g2_win32_DrawString }, + { g2_QueryPointer, g2_win32_QueryPointer }, + { g2_FUNIX_NULL, NULL } }; + + +#endif /* G2_WIN32_FUNIX_H */ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_thread.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_thread.c new file mode 100755 index 00000000..7c315369 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2_win32_thread.c @@ -0,0 +1,213 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ + +#include +#include +#include +#include +#include + +#include "g2_win32_P.h" + +#include "resource.h" + + + +int WINAPI About(HWND hDlg,UINT message, WPARAM wParam,LPARAM lParam) +{ + switch (message){ + case WM_INITDIALOG: + return TRUE; + + case WM_COMMAND: + if (wParam == IDOK) + EndDialog(hDlg,wParam); + break; + } + + return FALSE; +} + + + +LRESULT CALLBACK g2_WndProc(HWND hWnd, UINT message, WPARAM wParam, LPARAM lParam) +{ + PAINTSTRUCT ps; + HDC hDC; + RECT Rect; + struct g2_win32_STRUCT *pdp; + + pdp = (struct g2_win32_STRUCT *)GetWindowLong(hWnd, GWL_USERDATA); + switch (message) { + + case WM_PAINT: + if (pdp == NULL) break; + if (pdp->hBitmap == NULL) break; + +// printf("Received WM_PAINT\n"); + + hDC = BeginPaint (hWnd, &ps); + GetClientRect(hWnd,&Rect); + BitBlt( hDC, Rect.left, Rect.top, Rect.right - Rect.left, + Rect.bottom - Rect.top, pdp->hMemDC, 0, 0, SRCCOPY ); + EndPaint (hWnd, &ps); + return 0L; + + case WM_DESTROY: + +// printf("Received WM_DESTROY\n"); + g2_win32_Cleanup(0,pdp); + ExitThread(0); + return 0L; + + case WM_COMMAND: + switch(LOWORD(wParam)){ + + case ID_FILE_COPY: + if (OpenClipboard(hWnd)) + { + HBITMAP hBitmap; + + EmptyClipboard(); + + if (pdp->hBitmap) + { + if (hBitmap = CopyImage(pdp->hBitmap,IMAGE_BITMAP, + 0,0,LR_COPYRETURNORG)); + SetClipboardData(CF_BITMAP, hBitmap); + } + CloseClipboard(); + } + return 0L; + + case ID_FILE_ABOUT: + if(DialogBox(g2res_DLL,"ABOUTBOX",hWnd,(DLGPROC)About) == -1) + errhandler("Failed to create Dialogbox",NULL); + return 0L; + + case ID_FILE_CLOS: + g2_win32_Delete(0,pdp); + return 0L; + + default: + return (DefWindowProc(hWnd, message, wParam, lParam)); + } + + default: + return (DefWindowProc(hWnd, message, wParam, lParam)); + } +/* we should never get here */ +return -1; +} + +long WINAPI g2_StartThread(struct g2_win32_STRUCT *pdp) +{ +RECT Rect; +HWND hWnd; +MSG msg; +HDC hDC; +HMENU hmenu; +DWORD style; +RECT frame; + +hmenu = NULL; +if (g2res_DLL != NULL) + { + hmenu = LoadMenu(g2res_DLL,"G2WIN32"); + if (hmenu == NULL) errhandler("Load menu failed",NULL); + } + +style = WS_POPUPWINDOW |WS_OVERLAPPED | WS_CAPTION | WS_MINIMIZEBOX; +frame.left = 0; +frame.top = 0; +frame.right = pdp->nWidth; +frame.bottom = pdp->nHeight - ((hmenu==NULL)?GetSystemMetrics(SM_CYMENU):0); + +AdjustWindowRect(&frame,style,1); + +/* Save the instance handle in static variable, which will be used in */ +/* many subsequence calls from this application to Windows. */ + + /* Create a main window for this application instance. */ +pdp->hinst = GetModuleHandle(NULL); + +hWnd = CreateWindow( + "g2Window", // See RegisterClass() call. + pdp->title, // Text for window title bar. + style, + pdp->x, pdp->y, + frame.right - frame.left, // width + frame.bottom - frame.top, // height + NULL, // Overlapped windows have no parent. + hmenu, // Use the window class menu. + 0, // This instance owns this window. + NULL // Pointer not needed. + ); + + // If window could not be created, return "failure" + +if (!hWnd) + { + errhandler("CreateWindow",NULL); + return (FALSE); // return failure :(( + } + +#define WIDTH(x) (x.right-x.left+1) // Macro to get rect width +#define HEIGHT(x) (x.bottom-x.top+1) // Macro to get rect height + +// How big is the window? +GetClientRect( hWnd, &Rect ); + +// Need a DC +hDC = GetDC( hWnd ); +SetBkColor(hDC,RGB(255,255,255)); +// Create a bitmap big enough to hold the window's image +pdp->hBitmap = CreateCompatibleBitmap( hDC, WIDTH(Rect), HEIGHT(Rect) ); +// printf("memdc size: %d %d\n",WIDTH(Rect),HEIGHT(Rect)); +// Create MemDC +pdp->hMemDC = CreateCompatibleDC(hDC); +SelectObject( pdp->hMemDC, pdp->hBitmap ); +// clean up +ReleaseDC( hWnd, hDC ); +#undef WIDTH +#undef HEIGHT + + + +SetWindowLong(hWnd, GWL_USERDATA, (long)pdp); + + pdp->hwndThreadWindow = hWnd; + // Make the window visible; update its client area; and return "success" + ShowWindow(hWnd, SW_SHOWDEFAULT); // Show the window + UpdateWindow(hWnd); // Sends WM_PAINT message + //printf("pdp->messageloop ->= 1;\n"); + pdp->messageloop = 1; + //printf("pdp->messageloop = 1;\n"); + + while (GetMessage(&msg, NULL, 0, 0)) { + TranslateMessage(&msg); + DispatchMessage(&msg); + } + + + return (TRUE); // Returns success :) +} + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2res.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2res.c new file mode 100755 index 00000000..b729ff7f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/g2res.c @@ -0,0 +1,7 @@ +#include + + +BOOL WINAPI DllMain( HINSTANCE hInstance, DWORD dwReason, LPVOID lpv) +{ + return 1; +} \ No newline at end of file diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/resource.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/resource.h new file mode 100755 index 00000000..ff8f985b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/Win32/resource.h @@ -0,0 +1,21 @@ +//{{NO_DEPENDENCIES}} +// Microsoft Developer Studio generated include file. +// Used by g2_win32.rc +// +#define IDI_ICON1 101 +#define IDD_DIALOG1 104 +#define ID_FILE_SAVEASBMP 40002 +#define ID_FILE_COPY 40003 +#define ID_FILE_ABOUT 40005 +#define ID_FILE_CLOS 40006 + +// Next default values for new objects +// +#ifdef APSTUDIO_INVOKED +#ifndef APSTUDIO_READONLY_SYMBOLS +#define _APS_NEXT_RESOURCE_VALUE 107 +#define _APS_NEXT_COMMAND_VALUE 40007 +#define _APS_NEXT_CONTROL_VALUE 1000 +#define _APS_NEXT_SYMED_VALUE 101 +#endif +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Entries new file mode 100755 index 00000000..17848105 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Entries @@ -0,0 +1 @@ +D diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Repository new file mode 100755 index 00000000..d0f45182 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/X11/CVS diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Entries b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Entries new file mode 100755 index 00000000..b6003b5d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Entries @@ -0,0 +1,6 @@ +D/CVS//// +/g2.xpm/1.1/Mon Jan 18 10:56:52 1999// +/g2_X11.c/1.1/Tue Jun 14 20:44:20 2005// +/g2_X11.h/1.1/Tue Apr 17 20:16:38 2001// +/g2_X11_P.h/1.1/Tue Jun 14 20:44:21 2005// +/g2_X11_funix.h/1.1/Tue Jun 14 20:44:21 2005// diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Repository b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Repository new file mode 100755 index 00000000..724d8ea4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Repository @@ -0,0 +1 @@ +RNAforester/g2-0.70/src/X11 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Root b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Root new file mode 100755 index 00000000..9c9d467e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Root @@ -0,0 +1 @@ +mhoechsm@porta.techfak.uni-bielefeld.de:/homes/mhoechsm/cvsroot diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Template b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/CVS/Template new file mode 100755 index 00000000..e69de29b diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2.xpm b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2.xpm new file mode 100755 index 00000000..339c0fef --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2.xpm @@ -0,0 +1,180 @@ +/* XPM */ +static char * g2_xpm[] = { +"40 40 137 2", +" c none", +". c #6B1214", +"+ c #6E1314", +"@ c #891C18", +"# c #8F1E19", +"$ c #821A17", +"% c #841A17", +"& c #BD2D1E", +"* c #EC3C24", +"= c #C22F1F", +"- c #7D1816", +"; c #851A17", +"> c #731515", +", c #BC2C1E", +"' c #B1291D", +") c #8D1D18", +"! c #721415", +"~ c #942019", +"{ c #A0231B", +"] c #C93120", +"^ c #6A1214", +"/ c #6D1314", +"( c #771616", +"_ c #8A1C18", +": c #A5251B", +"< c #C12E1F", +"[ c #D53522", +"} c #9E231B", +"| c #6F1315", +"1 c #681114", +"2 c #7A1716", +"3 c #831A17", +"4 c #7F1817", +"5 c #911E19", +"6 c #AA271C", +"7 c #C73020", +"8 c #E03823", +"9 c #E73B24", +"0 c #D23421", +"a c #B42A1D", +"b c #962019", +"c c #7E1817", +"d c #711415", +"e c #9B221A", +"f c #7F1917", +"g c #AF281D", +"h c #CA3120", +"i c #DD3722", +"j c #E13923", +"k c #D73522", +"l c #C42F1F", +"m c #AE281D", +"n c #9D221A", +"o c #931F19", +"p c #8E1E19", +"q c #861B18", +"r c #751515", +"s c #B52A1D", +"t c #881B18", +"u c #6C1214", +"v c #761615", +"w c #AD281C", +"x c #D83622", +"y c #D03321", +"z c #C83120", +"A c #C22E1F", +"B c #BD2D1F", +"C c #A9261C", +"D c #A4251B", +"E c #DB3722", +"F c #851B17", +"G c #A3241B", +"H c #E43A23", +"I c #B32A1D", +"J c #9C221A", +"K c #9E231A", +"L c #D33421", +"M c #901E19", +"N c #A7261C", +"O c #C02E1F", +"P c #AC271C", +"Q c #8E1D18", +"R c #761515", +"S c #691114", +"T c #8B1C18", +"U c #761616", +"V c #B82B1E", +"W c #871B18", +"X c #671114", +"Y c #8C1D18", +"Z c #7B1716", +"` c #861B17", +" . c #881C18", +".. c #801917", +"+. c #A6251C", +"@. c #CB3120", +"#. c #DC3722", +"$. c #791716", +"%. c #9A221A", +"&. c #BA2C1E", +"*. c #98211A", +"=. c #B2291D", +"-. c #99211A", +";. c #B62B1E", +">. c #D13421", +",. c #D53521", +"'. c #CE3321", +"). c #952019", +"!. c #EB3C24", +"~. c #E83B24", +"{. c #DE3823", +"]. c #9F231B", +"^. c #BB2C1E", +"/. c #CF3321", +"(. c #C32F1F", +"_. c #7C1816", +":. c #7E1816", +"<. c #DA3622", +"[. c #E63A24", +"}. c #EA3C24", +"|. c #B0281D", +"1. c #D63522", +"2. c #E23923", +"3. c #E53A23", +"4. c #AB271C", +"5. c #D93622", +"6. c #811917", +"7. c #97211A", +"8. c #7C1716", +"9. c #741515", +"0. c #A8261C", +"a. c #A2241B", +"b. c #D43421", +"c. c #D43521", +"d. c #CC3220", +"e. c #E93B24", +"f. c #BC2D1E", +" ", +" ", +" ", +" ", +" ", +" ", +" ", +" . + @ ", +" # $ % & * = - ", +" ; > , ' ", +" ) ! ~ ", +" { ] ", +" . ^ / ( _ : < [ & } $ | 1 ^ 2 ", +" _ 3 4 $ 5 6 7 8 * 9 0 a b c d . . ^ $ 7 ", +" e @ f 3 ~ g h i j k l m n o p ) _ q % r s ", +" t ! u v # w x y z l A B s C D E ", +" ^ | F G H E h I J K D L ", +" 3 M N O P Q R u S S . T U ", +" } 6 a ^ / f V W X Y 6 5 Z ( u ", +" ` .Y ..M G +.{ @.#.x [ C u 2 ", +" / $.# $ .Y ", +" f %.&. . | $. ", +" *.' = v @ +. ", +" g &.&.=. $ -.;.>. ", +" ,.,.0 y '. ).' 7 >. ", +" !.!.~.{.] $ ].^./.k k ", +" ~.E (.: T _.:.# C l <.[.!.!.}. ", +" 7 |.].e G a 7 1.{.j 2.3.9 9 ", +" ].K G 4.' a ;.&.(. #.j 5. ", +" 6.% ) }.8 ] ", +" >.;.e ", +" G _ ( u ", +" 7.t 8.R 9.> ", +" f o +.' I m 0.D G a.].). ", +" 7 b.5.x 1.[ 1.c.d.^.a. ", +" * e.9 9 }.* [.1.f. ", +" ", +" ", +" ", +" "}; diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.c new file mode 100755 index 00000000..d2f14f27 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.c @@ -0,0 +1,797 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include +#include +#include +#include +#include +#include + +#include "g2.h" +#include "g2_device.h" +#include "g2_util.h" +#include "g2_X11_P.h" +#include "g2_X11.h" +#include "g2_X11_funix.h" +#include "g2_config.h" + + +static int N_X11=0; +static g2_X11_device *g2_X11_dev=NULL; + +/** + * \ingroup physdev + * \defgroup X11 X11 + */ + + +/** + * + * Open a simple X11 window (physical device device). + * + * \param width window width + * \param height window height + * \return physical device id + * + * \ingroup X11 + */ +int g2_open_X11(int width, int height) +{ + return g2_open_X11X(width, height, + 10, 10, + NULL, NULL, + NULL, -1, -1); +} + + + +/** + * + * Open a X11 window (physical device device). If \a icon_width or \a + * icon_height is smaller than 0, the \a icon_data is interpreted as a + * file name. + * + * \param width window width + * \param height window height + * \param x x position on screen + * \param y y position on screen + * \param window_name hint for window manager + * \param icon_name hint for window manager + * \param icon_data icon bitmap (\a icon_width * \a icon_height bits) or file name containing bitmap + * (if \a icon_width <= 0 or \a icon_height <= 0) + * \param icon_width icon width + * \param icon_height icon height + * \return physical device id + * + * \ingroup X11 + */ +int g2_open_X11X(int width, int height, + int x, int y, + char *window_name, char *icon_name, + char *icon_data, int icon_width, int icon_height) +{ + g2_X11_device *xout=NULL; + int pid=-1, i; + char name[32]; + int vid; + + if(g2_X11_dev==NULL) { + g2_X11_dev=g2_malloc(sizeof(g2_X11_device)); + N_X11=1; /* first X11 device */ + xout=&g2_X11_dev[N_X11-1]; + pid=0; + } else { + for(i=0;iwidth=width; /* set window size */ + xout->height=height; + + xout->NofInks=0; /* reset inks */ + xout->inks=NULL; + + vid = g2_register_physical_device(pid, NULL, + g2_IntCoor, g2_X11_funix, + 1.0, -1.0, + 0.0, height-1); + + sprintf(name, "g2: %d", vid); /* set window and icon names */ + if(window_name==NULL) + window_name=name; + if(icon_name==NULL) + icon_name=name; + + g2_X11_init_X11X(pid, width, height, + x, y, + window_name, icon_name, + icon_data, icon_width, icon_height); + + + /* g2 calls */ + g2_allocate_basic_colors(vid); + g2_set_background(vid, 0); + g2_pen(vid, 1); + + return vid; +} + + + + +/* + * + * Extended version of the InitX11 + * + */ +int g2_X11_init_X11X(int pid, int width, int height, + int xposition, int yposition, + char *window_name, char *icon_name, + char *icon_data, + unsigned int icon_width, unsigned int icon_height) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + Window root; + XSetWindowAttributes wattr; + XEvent event; + Pixmap iconPixmap; + XSizeHints sizehints; + int xhot, yhot, rv; + XColor w_scr, w_exa, r_scr, r_exa; + XClassHint class_hint; + + if((xout->display=XOpenDisplay(NULL))==NULL) { + g2_log(Error, "g2: can't open display\n"); + exit(-1); + } + + + xout->root=RootWindow(xout->display, DefaultScreen(xout->display)); + root=xout->root; + + wattr.event_mask=ExposureMask; + xout->window=XCreateWindow(xout->display, root, + xposition, yposition, + width, height, + 0, + CopyFromParent, InputOutput, CopyFromParent, + CWEventMask, + &wattr); + + xout->gc=XCreateGC(xout->display, xout->window, + 0lu, NULL); + + xout->colormap=DefaultColormap(xout->display, + DefaultScreen(xout->display)); + + XAllocNamedColor(xout->display, xout->colormap, + "red", &r_scr, &r_exa); + XAllocNamedColor(xout->display, xout->colormap, + "white", &w_scr, &w_exa); + + + + if(icon_data!=NULL) { + if(icon_width<=0 || icon_height<=0) { /* read icon from file */ + rv=XReadBitmapFile(xout->display, xout->window, + icon_data, &icon_width, &icon_height, + &iconPixmap, &xhot, &yhot); + } else { /* icon is bitmap */ + iconPixmap=XCreatePixmapFromBitmapData(xout->display, + xout->window, + icon_data, + icon_width, icon_height, + 1ul, 0ul, 1); + rv=BitmapSuccess; + } + switch(rv) { + case BitmapOpenFailed: + fputs("g2(OpenXX): bitmap file open failed\n",stderr); + break; + case BitmapFileInvalid: + fputs("g2(OpenXX): bitmap file invalid\n",stderr); + break; + case BitmapNoMemory: + fputs("g2(OpenXX): no enough memeory for bitmap\n",stderr); + break; + } + } else { /* no icon data avail. */ + unsigned char bitmapData[] = { + 0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00, + 0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00, + 0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00, + 0x00,0x00,0x00,0x00,0x00,0x80,0x03,0x00,0x00,0x00,0xe0, + 0x0d,0x00,0x00,0x00,0x60,0x0c,0x00,0x00,0x00,0x20,0x18, + 0x00,0x00,0x00,0x00,0x10,0x00,0xf8,0xe3,0x07,0x08,0x00, + 0xfe,0xfa,0x07,0x0c,0x00,0xbf,0x6e,0x07,0x06,0x80,0x0f, + 0xf5,0x00,0x01,0x80,0x05,0x34,0x80,0x09,0xc0,0x03,0x78, + 0xe0,0x18,0x80,0x00,0x70,0xe0,0x1e,0xc0,0x01,0x70,0x70, + 0x1b,0xc0,0x01,0x50,0x00,0x00,0xc0,0x01,0x70,0x00,0x00, + 0xc0,0x00,0x70,0x00,0x00,0x40,0x03,0x38,0x00,0x00,0x80, + 0x05,0x50,0x00,0x00,0x80,0x0a,0x6e,0x00,0x00,0x00,0xfe, + 0x37,0x00,0x00,0x00,0x6a,0x59,0x00,0x00,0x00,0xbc,0x57, + 0x00,0x00,0x00,0xe0,0x50,0x00,0x00,0x00,0x00,0x60,0x00, + 0x00,0x00,0x00,0x78,0x00,0x00,0x00,0x00,0x7e,0x00,0x00, + 0x00,0x7c,0x2b,0x00,0x00,0x00,0xa4,0x1d,0x00,0x00,0x00, + 0xb8,0x06,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00, + 0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00,0x00, + 0x00,0x00}; + iconPixmap=XCreatePixmapFromBitmapData(xout->display, xout->window, + (char*)bitmapData, + 40u, 40u, + w_scr.pixel, r_scr.pixel, + 1ul); + } + + sizehints.x = xposition; + sizehints.y = yposition; + sizehints.min_width = width; + sizehints.max_width = width; + sizehints.min_height = height; + sizehints.max_height = height; + sizehints.flags = PPosition | PMinSize | PMaxSize; + XSetStandardProperties(xout->display, xout->window, + window_name, icon_name, iconPixmap, + (char **)NULL, 0, &sizehints); + + class_hint.res_name = "g2"; + class_hint.res_class = "G2"; + XSetClassHint(xout->display, xout->window, &class_hint); + + + XMapRaised(xout->display, xout->window); + + /* XSetWindowBackground(xout->display, xout->window, w_scr.pixel); */ + XClearWindow(xout->display,xout->window); + + g2_X11_paper(pid, NULL, 0); + g2_X11_set_font_size(pid, NULL, 12); + /* wait expose event */ + /* (no back. store) */ + while(!XCheckWindowEvent(xout->display,xout->window, + ExposureMask,&event)) + ; + + + wattr.event_mask=NoEventMask; /* set NoEventMask */ + wattr.backing_store=Always; /* set backing store */ + XChangeWindowAttributes(xout->display, xout->window, + CWEventMask|CWBackingStore, + &wattr); + + xout->dest = xout->window; + + xout->backing_pixmap = None; + + if(XDoesBackingStore(XDefaultScreenOfDisplay(xout->display))!=Always) { + if(g2_EmulateBackingStore) { + g2_log(Warning, "g2: Warning! Backing store is not available. Allocating pixmap instead.\n"); + + xout->backing_pixmap = XCreatePixmap(xout->display, xout->window, + xout->width, xout->height, + DefaultDepth(xout->display, DefaultScreen(xout->display))); + XSetWindowBackgroundPixmap(xout->display, xout->window, + xout->backing_pixmap); + + XSetForeground (xout->display, xout->gc, w_scr.pixel); + + XFillRectangle(xout->display, xout->backing_pixmap, xout->gc, + 0, 0, xout->width, xout->height); + xout->dest = xout->backing_pixmap; + } else { + g2_log(Warning, "g2: Warning! Backing store is not available.\n"); + } + } + + XFlush(xout->display); + return 0; +} + + + + +int g2_X11_delete(int pid, void *pdp) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XUnmapWindow(xout->display, xout->window); + if (xout->backing_pixmap != None) + XFreePixmap(xout->display,xout->backing_pixmap); + XDestroyWindow(xout->display, xout->window); + XDestroyWindow(xout->display, xout->root); + XFreeGC(xout->display, xout->gc); + XFreeColormap(xout->display, xout->colormap); + XCloseDisplay(xout->display); + if(xout->inks!=NULL) + g2_free(xout->inks); + xout->width=xout->height=0; + xout->display=NULL; + return 0; +} + + + +int g2_X11_clear(int pid, void *pdp) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + + if (xout->backing_pixmap == None) { + XClearWindow(xout->display,xout->window); + } else { + XSetForeground (xout->display, xout->gc, + xout->background); + XFillRectangle(xout->display, xout->dest, xout->gc, + 0, 0, xout->width, xout->height); + } + g2_X11_flush(pid, pdp); + return 0; +} + + + +int g2_X11_flush(int pid, void *pdp) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + if( xout->backing_pixmap != None ) { + XCopyArea(xout->display, xout->dest, xout->window, xout->gc, + 0, 0, xout->width, xout->height, 0, 0); + } + XFlush(xout->display); + return 0; +} + + + +int g2_X11_ink(int pid, void *pdp, + double red, double green, double blue) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XColor color; + + color.flags=DoRed|DoGreen|DoBlue; + color.red = (int)(red * USHRT_MAX); + color.green = (int)(green * USHRT_MAX); + color.blue = (int)(blue * USHRT_MAX); + if(XAllocColor(xout->display,xout->colormap,&color)) { + xout->NofInks++; + if(xout->inks==NULL) + xout->inks= + (unsigned long *)g2_malloc(xout->NofInks*sizeof(unsigned long)); + else + xout->inks= + (unsigned long *)g2_realloc((void *)xout->inks, + xout->NofInks*sizeof(unsigned long)); + if(xout->inks==NULL) { + fputs("g2: not enough memory\n",stderr); + return -1; + } + xout->inks[xout->NofInks-1]=color.pixel; + return xout->NofInks-1; + } else { + fputs("g2: color is not available\n",stderr); + return -1; + } +} + + +int g2_X11_clear_palette(int pid, void *pdp) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XFreeColors(xout->display,xout->colormap, + xout->inks,xout->NofInks,0x0ul); + xout->NofInks=0; + if(xout->inks!=NULL) + free(xout->inks); + xout->inks=NULL; + return 0; +} + + +int g2_X11_set_background(int pid, void *pdp, int color) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + if(color>=xout->NofInks || color<0) + return -1; + if (xout->backing_pixmap == None) + { + XSetWindowBackground(xout->display,xout->dest, + xout->inks[color]); + } + else + { + xout->background = xout->inks[color]; + } + g2_X11_clear(pid,pdp); + return 0; +} + + +int g2_X11_pen(int pid, void *pdp, int color) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + if(color>=xout->NofInks || color<0) + return -1; + XSetForeground(xout->display, xout->gc, xout->inks[color]); + return 0; +} + + + +int g2_X11_paper(int pid, void *pdp, int color) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + if(color>=xout->NofInks || color<0) + return -1; + XSetBackground(xout->display, xout->gc, xout->inks[color]); + return 0; +} + + +int g2_X11_set_line_width(int pid, void *pdp, int w) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XGCValues val; + + val.line_width=w; + XChangeGC(xout->display, xout->gc, GCLineWidth, &val); + return 0; +} + + +int g2_X11_set_dash(int pid, void *pdp, int n, int *data) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XGCValues val; + int i; + + if(n<=0 || data==NULL) { + val.line_style=LineSolid; + XChangeGC(xout->display, xout->gc, GCLineStyle,&val); + } else { + char *ch_data; + ch_data=g2_malloc(n*sizeof(char)); + val.line_style=LineOnOffDash; + for(i=0;i0) + ch_data[i]=(char)data[i]; + else + ch_data[i]=1; + XChangeGC(xout->display, xout->gc, GCLineStyle, &val); + XSetDashes(xout->display, xout->gc, 0, ch_data, n); + g2_free(ch_data); + } + return 0; +} + + +int g2_X11_set_font_size(int pid, void *pdp, int size) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XFontStruct *fnt_str; + char font_name[256]; + int sizei, d, n; + + sizei=dtoi(size); + + if(sizei<=0) + sizei=1; /* set to smallest size */ + + for(n=1;n<32;n++) { + d=((n&0x01)? -1:1)*(n>>1); + sprintf(font_name, g2_X11Font, sizei+d); + fnt_str=XLoadQueryFont(xout->display, font_name); + if(fnt_str==NULL) { + if(!d) + fprintf(stderr,"g2: can not load font: '%s'\n",font_name); + } else { + XSetFont(xout->display,xout->gc,fnt_str->fid); + if(d) + fprintf(stderr,"g2: using '%s' instead\n",font_name); + return 0; + } + } + fprintf(stderr, "g2: are you sure about %d point size\n", size); + return -1; +} + + +int g2_X11_plot(int pid, void *pdp, int x, int y) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawPoint(xout->display, xout->dest, xout->gc, + x, y); + return 0; +} + + +int g2_X11_line(int pid, void *pdp, int x1, int y1, int x2, int y2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawLine(xout->display,xout->dest,xout->gc, + x1, y1, x2, y2); + return 0; +} + + +int g2_X11_poly_line(int pid, void *pdp, int N, int *p) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XPoint *points; + int i; + points=g2_malloc(N*sizeof(XPoint)); + for(i=0;idisplay,xout->dest,xout->gc, + points, N, + CoordModeOrigin); + g2_free(points); + return 0; +} + + +int g2_X11_polygon(int pid, void *pdp, int N, int *p) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XPoint *points; + int i; + points=g2_malloc((N+1)*sizeof(XPoint)); + for(i=0;idisplay,xout->dest,xout->gc, + points, N+1, + CoordModeOrigin); + g2_free(points); + return 0; +} + + +int g2_X11_filled_polygon(int pid, void *pdp, int N, int *p) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XPoint *points; + int i; + points=g2_malloc((N+1)*sizeof(XPoint)); + for(i=0;idisplay,xout->dest,xout->gc, + points, N+1, + Complex, CoordModeOrigin); + g2_free(points); + return 0; +} + + +int g2_X11_triangle(int pid, void *pdp, + int x1, int y1, + int x2, int y2, + int x3, int y3) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XPoint points[4]; + points[0].x=x1; points[0].y=y1; + points[1].x=x2; points[1].y=y2; + points[2].x=x3; points[2].y=y3; + points[3].x=x1; points[3].y=y1; + XDrawLines(xout->display,xout->dest,xout->gc, + points, 4, CoordModeOrigin); + return 0; +} + + +int g2_X11_filled_triangle(int pid, void *pdp, + int x1, int y1, + int x2, int y2, + int x3, int y3) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XPoint points[4]; + points[0].x=x1; points[0].y=y1; + points[1].x=x2; points[1].y=y2; + points[2].x=x3; points[2].y=y3; + points[3].x=x1; points[3].y=y1; + XFillPolygon(xout->display,xout->dest,xout->gc, + points, 4, Convex, CoordModeOrigin); + return 0; +} + + +int g2_X11_rectangle(int pid, void *pdp, int x1, int y1, int x2, int y2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawRectangle(xout->display,xout->dest,xout->gc, + x1, y1, x2-x1, y2-y1); + return 0; +} + + + +int g2_X11_filled_rectangle(int pid, void *pdp, int x1, int y1, int x2, int y2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawRectangle(xout->display,xout->dest,xout->gc, + x1, y1, x2-x1, y2-y1); + XFillRectangle(xout->display,xout->dest,xout->gc, + x1, y1, x2-x1, y2-y1); + return 0; +} + + +int g2_X11_arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + double a0, d; + + a0=fmod(a1, 360.) + (a1<0? 360:0); /* map a1 to [0, 360) */ + d=a2>a1? a2-a1:a2-a1+360; + + XDrawArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + (int)(a0*64.), (int)(d*64.)); + return 0; +} + + +int g2_X11_filled_arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + double a0, d; + + a0=fmod(a1, 360.) + (a1<0? 360:0); /* map a1 to [0, 360) */ + d=a2>a1? a2-a1:a2-a1+360; + + XDrawArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + (int)(a0*64.), (int)(d*64.)); + XFillArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + (int)(a0*64.), (int)(d*64.)); + return 0; +} + + +int g2_X11_ellipse(int pid, void *pdp, int x, int y, int r1, int r2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + 0,360*64); + return 0; +} + + +int g2_X11_filled_ellipse(int pid, void *pdp, int x, int y, int r1, int r2) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + 0,360*64); + XFillArc(xout->display,xout->dest,xout->gc, + x-r1, y-r2, + r1*2, r2*2, + 0,360*64); + XFlush(xout->display); + return 0; +} + + +int g2_X11_draw_string(int pid, void *pdp, int x, int y, const char *text) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XDrawString(xout->display,xout->dest,xout->gc, + x, y, text, strlen(text)); + return 0; +} + + +int g2_X11_image(int pid, void *pdp, + int x, int y, int width, int height, int *pen_array) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + XImage *image=NULL; + Screen *screen; + unsigned long *ink_array; + int i; + + ink_array=malloc(sizeof(unsigned long)*width*height); + for(i=0;iinks[pen_array[i]]; + + screen=DefaultScreenOfDisplay(xout->display); + image=XCreateImage(xout->display, + DefaultVisualOfScreen(screen), + DefaultDepthOfScreen(screen), + ZPixmap, + 0, /* offset */ + (char *)ink_array, + width, height, + sizeof(unsigned long)*8, /* bitmap pad */ + 0); /* bytes per line */ + /* XInitImage(image); problems with AIX ?!! */ + XPutImage(xout->display, xout->dest, xout->gc, + image, + 0, 0, + x, y, width, height); + + XDestroyImage(image); + free(ink_array); + return 0; +} + + +int g2_X11_query_pointer(int pid, void *pdp, + int *x, int *y, unsigned int *button) +{ + Bool rv; + g2_X11_device *xout=&g2_X11_dev[pid]; + Window root, child; + int rx, ry; + + rv = XQueryPointer(xout->display, xout->window, + &root, &child, &rx, &ry, + x, y, button); + + if(rv) + return 0; + else + return 1; +} + + + +int g2_X11_get_pd_handles(int pid, void *pdp, void *handles[G2_PD_HANDLES_SIZE]) +{ + g2_X11_device *xout=&g2_X11_dev[pid]; + + handles[0]=xout->display; + handles[1]=&xout->window; + handles[2]=&xout->root; + handles[3]=&xout->colormap; + handles[4]=&xout->gc; + handles[5]=&xout->dest; + return 0; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.h new file mode 100755 index 00000000..4db6bf94 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11.h @@ -0,0 +1,45 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_X11_H +#define _G2_X11_H + +#if defined(__cplusplus) +extern "C" +{ +#endif + + +int g2_open_X11(int width, int height); + +int g2_open_X11X(int width, int height, + int x, int y, + char *window_name, char *icon_name, + char *icon_data, + int icon_width, int icon_height); + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_X11_H */ + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_P.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_P.h new file mode 100755 index 00000000..9c9f3ccb --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_P.h @@ -0,0 +1,94 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_X11_P_H +#define _G2_X11_P_H + +#include + +#include "g2.h" + +typedef struct { + Display *display; + Window window; + Window root; + Colormap colormap; + GC gc; + Drawable dest; + Pixmap backing_pixmap; + + + unsigned long *inks; /* allocated colors*/ + int NofInks; /* N of allocated colors */ + int width; /* window dimensions */ + int height; + int background; +} g2_X11_device; + + +int g2_X11_init_X11X(int pid, int width, int height, + int xposition, int yposition, + char *window_name, char *icon_name, + char *icon_data, + unsigned int icon_width, unsigned int icon_height); +int g2_X11_delete(int pid, void *pdp); +int g2_X11_clear(int pid, void *pdp); +int g2_X11_flush(int pid, void *pdp); +int g2_X11_ink(int pid, void *pdp, + double red, double green, double blue); +int g2_X11_clear_palette(int pid, void *pdp); +int g2_X11_reset_palette(int pid, void *pdp); +int g2_X11_set_background(int pid, void *pdp, int color); +int g2_X11_pen(int pid, void *pdp, int color); +int g2_X11_paper(int pid, void *pdp, int color); +int g2_X11_set_line_width(int pid, void *pdp, int w); +int g2_X11_set_dash(int pid, void *pdp, int n, int *data); +int g2_X11_set_font_size(int pid, void *pdp, int size); +int g2_X11_plot(int pid, void *pdp, int x, int y); +int g2_X11_line(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_X11_poly_line(int pid, void *pdp, int N, int *p); +int g2_X11_polygon(int pid, void *pdp, int N, int *p); +int g2_X11_filled_polygon(int pid, void *pdp, int N, int *p); +int g2_X11_triangle(int pid, void *pdp, + int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_X11_filled_triangle(int pid, void *pdp, int x1, int y1, + int x2, int y2, + int x3, int y3); +int g2_X11_rectangle(int pid, void *pdp, int x1, int y1, int x2, int y2); +int g2_X11_filled_rectangle(int pid, void *pdp, + int x1, int y1, int x2, int y2); +int g2_X11_arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_X11_filled_arc(int pid, void *pdp, int x, int y, + int r1, int r2, double a1, double a2); +int g2_X11_ellipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_X11_filled_ellipse(int pid, void *pdp, int x, int y, int r1, int r2); +int g2_X11_draw_string(int pid, void *pdp, int x, int y, const char *text); +int g2_X11_image(int pid, void *pdp, + int x, int y, int width, int height, int *pen_array); +int g2_X11_query_pointer(int pid, void *pdp, + int *x, int *y, unsigned int *button); +int g2_X11_get_pd_handles(int pid, void *pdp, void *handles[G2_PD_HANDLES_SIZE]); +#endif /* _G2_X11_P_H */ + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_funix.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_funix.h new file mode 100755 index 00000000..66f9b1fe --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/X11/g2_X11_funix.h @@ -0,0 +1,60 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_X11_FUNIX_H +#define _G2_X11_FUNIX_H + +#include "g2_X11_P.h" +#include "g2_physical_device.h" + + +const g2_funix_fun g2_X11_funix[] = { + { g2_Delete, g2_X11_delete }, + { g2_Ink, g2_X11_ink }, + { g2_Pen, g2_X11_pen }, + { g2_SetBackground, g2_X11_set_background }, + { g2_ClearPalette, g2_X11_clear_palette }, + { g2_SetLineWidth, g2_X11_set_line_width }, + { g2_SetDash, g2_X11_set_dash }, + { g2_SetFontSize, g2_X11_set_font_size }, + { g2_Clear, g2_X11_clear }, + { g2_Flush, g2_X11_flush }, + { g2_Save, g2_X11_flush }, + { g2_Plot, g2_X11_plot }, + { g2_Line, g2_X11_line }, + { g2_PolyLine, g2_X11_poly_line }, + { g2_Polygon, g2_X11_polygon }, + { g2_FilledPolygon, g2_X11_filled_polygon }, + { g2_Rectangle, g2_X11_rectangle }, + { g2_FilledRectangle, g2_X11_filled_rectangle }, + { g2_Triangle, g2_X11_triangle }, + { g2_FilledTriangle, g2_X11_filled_triangle }, + { g2_Arc, g2_X11_arc }, + { g2_FilledArc, g2_X11_filled_arc }, + { g2_Ellipse, g2_X11_ellipse }, + { g2_FilledEllipse, g2_X11_filled_ellipse }, + { g2_Circle, NULL }, + { g2_FilledCircle, NULL }, + { g2_String, g2_X11_draw_string }, + { g2_Image, NULL }, + { g2_QueryPointer, g2_X11_query_pointer }, + { g2_GetPDHandles, g2_X11_get_pd_handles }, + { g2_FUNIX_NULL, NULL } }; + + +#endif /* _G2_X11_FUNIX_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2.h new file mode 100755 index 00000000..e16a9229 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2.h @@ -0,0 +1,200 @@ +/***************************************************************************** +** Copyright (C) 1998-2005 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_H +#define _G2_H + + +/* g2 version */ +#define G2_VERSION "0.70" + + +#if defined(__cplusplus) +extern "C" +{ +#endif + +/* Common Library header for DLL and application */ +#ifdef WIN32 +#ifdef G2DLL +#ifdef MAKEDLL +/* Create DLL */ +#pragma message( "Building DLL library") +#define G2L __declspec( dllexport) +#else +/* Use DLL */ +#define G2L __declspec( dllimport) +#endif +#else +/* Use static win32 */ +#define G2L +#endif +#else +/* Use non-win32 */ +#define G2L +#endif + + +#define G2LD g2_ld() + +#if defined(SWIG) +#if defined(DO_X11) +%include "X11/g2_X11.h" +#endif +#if defined(DO_PS) +%include "PS/g2_PS.h" +#endif +#if defined(DO_GD) +%include "GD/g2_gd.h" +#endif +#if defined(DO_WIN32) +%include "WIN32/g2_win32.h" +#endif + +%module g2 + +%include typemaps.i + +%{ +#include "g2.h" +#if defined(DO_X11) +#include "g2_X11.h" +#endif +#if defined(DO_PS) +#include "g2_PS.h" +#endif +#if defined(DO_GD) +#include "g2_gd.h" +#endif +#if defined(DO_WIN32) +#include "WIN32/g2_win32.h" +#endif +%} + +#endif +/* end SWIG */ + + +enum QPshape { + QPrect, /**< rectangular quasi pixel */ + QPcirc /**< circle as a quasi pixel */ +}; + +/* compatibility with old versions */ +#define g2_draw_string(dev, x, y, text) g2_string((dev), (x), (y), (text)) + + + +G2L int g2_open_vd(void); +G2L void g2_attach(int vd_dev, int dev); +G2L void g2_detach(int vd_dev, int dev); + +G2L void g2_close(int dev); +G2L void g2_set_auto_flush(int dev, int on_off); +G2L void g2_flush(int dev); +G2L void g2_save(int dev); +G2L void g2_set_coordinate_system(int dev, double x_origin, double y_origin, + double x_mul, double y_mul); + +G2L int g2_ld(); +G2L void g2_set_ld(int dev); + +G2L int g2_ink(int pd_dev, double red, double green, double blue); +G2L void g2_pen(int dev, int color); +G2L void g2_set_dash(int dev, int N, double *dashes); +G2L void g2_set_font_size(int dev, double size); +G2L void g2_set_line_width(int dev, double w); +G2L void g2_clear_palette(int dev); +G2L void g2_reset_palette(int dev); +G2L void g2_allocate_basic_colors(int dev); + +G2L void g2_clear(int dev); +G2L void g2_set_background(int dev, int color); + +G2L void g2_move(int dev, double x, double y); +G2L void g2_move_r(int dev, double dx, double dy); + +G2L void g2_plot(int dev, double x, double y); +G2L void g2_plot_r(int dev, double dx, double dy); +G2L void g2_line(int dev, double x1, double y1, double x2, double y2); +G2L void g2_line_r(int dev, double dx, double dy); +G2L void g2_line_to(int dev, double x, double y); +G2L void g2_poly_line(int dev, int N_pt, double *points); +G2L void g2_triangle(int dev, double x1, double y1, + double x2, double y2, + double x3, double y3); +G2L void g2_filled_triangle(int dev, double x1, double y1, + double x2, double y2, + double x3, double y3); +G2L void g2_rectangle(int dev, double x1, double y1, double x2, double y2); +G2L void g2_filled_rectangle(int dev, + double x1, double y1, double x2, double y2); +G2L void g2_polygon(int dev, int N_pt, double *points); +G2L void g2_filled_polygon(int dev, int N_pt, double *points); +G2L void g2_circle(int dev, double x, double y, double r); +G2L void g2_filled_circle(int dev, double x, double y, double r); +G2L void g2_ellipse(int dev, double x, double y, double r1, double r2); +G2L void g2_filled_ellipse(int dev, double x, double y, double r1, double r2); +G2L void g2_arc(int dev, + double x, double y, + double r1, double r2, + double a1, double a2); +G2L void g2_filled_arc(int dev, double x, double y, + double r1, double r2, + double a1, double a2); +G2L void g2_string(int dev, double x, double y, const char *text); +G2L void g2_image(int dev, + double x, double y, int x_size, int y_size, int *pens); + +G2L void g2_set_QP(int dev, double d, enum QPshape shape); +G2L void g2_plot_QP(int dev, double x, double y); +#if !defined(SWIG) +G2L void g2_query_pointer(int dev, double *x, double *y, unsigned int *button); +#else +extern void g2_query_pointer(int dev, double *OUTPUT,double *OUTPUT,unsigned int *OUTPUT); +#endif + + + /* Tijs Michels */ + /* 06/16/99 */ + +G2L void g2_spline(int id, int n, double *points, int o); +G2L void g2_b_spline(int id, int n, double *points, int o); +G2L void g2_raspln(int id, int n, double *points, double tn); +G2L void g2_para_3(int id, int n, double *points); +G2L void g2_para_5(int id, int n, double *points); +G2L void g2_filled_spline(int id, int n, double *points, int o); +G2L void g2_filled_b_spline(int id, int n, double *points, int o); +G2L void g2_filled_raspln(int id, int n, double *points, double tn); +G2L void g2_filled_para_3(int id, int n, double *points); +G2L void g2_filled_para_5(int id, int n, double *points); + + +/** Actualy private function, but... **/ +G2L int g2_device_exist(int dix); + +/** Use only if you know what are you doing **/ +#define G2_PD_HANDLES_SIZE 32 +G2L void g2_get_pd_handles(int pd, void *handles[G2_PD_HANDLES_SIZE]); + + +#if defined(__cplusplus) +} /* end extern "C" */ +#endif + +#endif /* _G2_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_config.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_config.h new file mode 100755 index 00000000..f5607f0c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_config.h @@ -0,0 +1,42 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_CONFIG_H +#define _G2_CONFIG_H + +/* + * + * Some g2 defines + * + * Default behaviour is usually ok for most cases + * + */ + +/* g2 warnings are printed to stderr, larger 0=quiet, 1=errors, 2=warnings, 3=verbose, 4=debug */ +#define g2_LogLevel 1 + +/* set to 0 to disable backing store emulation */ +#define g2_EmulateBackingStore 1 + +/* X11 font, note %d for font size */ +#define g2_X11Font "-*-times-medium-r-normal--%d-*-*-*-*-*-*-*" + +/* PostScript font */ +#define g2_PSFont "/Times-Roman" + +#endif /* _G2_CONFIG_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.c new file mode 100755 index 00000000..7c04d2c8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.c @@ -0,0 +1,314 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + +#include "g2.h" +#include "g2_device.h" +#include "g2_physical_device.h" +#include "g2_util.h" +#include "g2_funix.h" + + + +/* + * + * Flush output + * + */ +void g2_flush_pd(g2_physical_device *pd) +{ + if(pd->ff[g2_Flush].fun!=NULL) { + pd->ff[g2_Flush].fun(pd->pid, pd->pdp); + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Save output + * + */ +void g2_save_pd(g2_physical_device *pd) +{ + if(pd->ff[g2_Save].fun!=NULL) { + pd->ff[g2_Save].fun(pd->pid, pd->pdp); + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Clear device + * + */ +void g2_clear_pd(g2_physical_device *pd) +{ + if(pd->ff[g2_Clear].fun!=NULL) { + pd->ff[g2_Clear].fun(pd->pid, pd->pdp); + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Set pen + * + */ +void g2_pen_pd(g2_physical_device *pd, int color) +{ + if(pd->ff[g2_Pen].fun!=NULL) { + pd->ff[g2_Pen].fun(pd->pid, pd->pdp, color); + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Set background color + * + */ +void g2_set_background_pd(g2_physical_device *pd, int color) +{ + if(pd->ff[g2_SetBackground].fun!=NULL) { + pd->ff[g2_SetBackground].fun(pd->pid, pd->pdp, color); + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Set ink + * + */ +int g2_ink_pd(g2_physical_device *pd, double red, double green, double blue) +{ + int rv=-1; + + if(pd->ff[g2_Ink].fun!=NULL) { + rv=pd->ff[g2_Ink].fun(pd->pid, pd->pdp, + red, green, blue); + } else { + /* emulate ... with .... */ + } + return rv; +} + + + + +/* + * + * Clear palette + * + */ +void g2_clear_palette_pd(g2_physical_device *pd) +{ + if(pd->ff[g2_ClearPalette].fun!=NULL) { + pd->ff[g2_ClearPalette].fun(pd->pid, pd->pdp); + } else { + /* emulate ... with .... */ + } +} + + +/* + * + * Allocate basic colors + * + */ +void g2_allocate_basic_colors_pd(g2_physical_device *pd) +{ + double ct[3]={0.0, 0.5, 1.0}; + int r, g, b; + + if(pd->ff[g2_Ink].fun!=NULL) { + pd->ff[g2_Ink].fun(pd->pid, pd->pdp, /* white */ + 1.0, 1.0, 1.0); + pd->ff[g2_Ink].fun(pd->pid, pd->pdp, /* black */ + 0.0, 0.0, 0.0); + for(r=0;r<3;r++) + for(g=0;g<3;g++) + for(b=0;b<3;b++) + if((r==2 && g==2 && b==2) || + (r==0 && g==0 && b==0)) + continue; + else + pd->ff[g2_Ink].fun(pd->pid, pd->pdp, + ct[r], ct[g], ct[b]); + } +} + + +/* + * + * Set font size + * + */ +void g2_set_font_size_pd(g2_physical_device *pd, double size) +{ + int is; + double ds; + + if(pd->ff[g2_SetFontSize].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + is=dtoi(size*fabs(pd->a22)); /* to pd coordinates */ + pd->ff[g2_SetFontSize].fun(pd->pid, pd->pdp, is); + break; + case g2_DoubleCoor: + ds=size*fabs(pd->a22); /* to pd coordinates */ + pd->ff[g2_SetFontSize].fun(pd->pid, pd->pdp, ds); + break; + } + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Set line width + * + */ +void g2_set_line_width_pd(g2_physical_device *pd, double w) +{ + int iw; + double dw; + + if(pd->ff[g2_SetLineWidth].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + iw=dtoi(w*fabs(pd->a22)); /* to pd coordinates */ + pd->ff[g2_SetLineWidth].fun(pd->pid, pd->pdp, iw); + break; + case g2_DoubleCoor: + dw=w*fabs(pd->a22); /* to pd coordinates */ + pd->ff[g2_SetLineWidth].fun(pd->pid, pd->pdp, dw); + break; + } + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Set dash + * + */ +void g2_set_dash_pd(g2_physical_device *pd, int N, double *dashes) +{ + int j; + double *dd=NULL; + int *id=NULL; + + if(pd->ff[g2_SetDash].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + if(dashes!=NULL) { + id=g2_malloc(N*sizeof(int)); + for(j=0;ja22)); + pd->ff[g2_SetDash].fun(pd->pid, pd->pdp, N, id); + g2_free(id); + } else + pd->ff[g2_SetDash].fun(pd->pid, pd->pdp, 0, NULL); + break; + case g2_DoubleCoor: + if(dashes!=NULL) { + dd=g2_malloc(N*sizeof(double)); + for(j=0;ja22); + pd->ff[g2_SetDash].fun(pd->pid, pd->pdp, N, dd); + g2_free(dd); + break; + } else + pd->ff[g2_SetDash].fun(pd->pid, pd->pdp, 0, NULL); + } + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Query pointer position and button state + * + */ +void g2_query_pointer_pd(g2_physical_device *pd, + double *x, double *y, unsigned int *button) +{ + int ix, iy; + double dx, dy; + + if(pd->ff[g2_QueryPointer].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + pd->ff[g2_QueryPointer].fun(pd->pid, pd->pdp, + &ix, &iy, button); + g2_pdc2uc(pd, ix, iy, x, y); + break; + case g2_DoubleCoor: + pd->ff[g2_QueryPointer].fun(pd->pid, pd->pdp, + &dx, &dy, button); + g2_pdc2uc(pd, dx, dy, x, y); + break; + } + } else { + /* no emulation for query pointer */ + } +} + + +/* + * + * Get low level handles + * + */ +void g2_get_pd_handles_pd(g2_physical_device *pd, void *handles[G2_PD_HANDLES_SIZE]) +{ + if(pd->ff[g2_GetPDHandles].fun!=NULL) { + pd->ff[g2_GetPDHandles].fun(pd->pid, pd->pdp, handles); + } else { + /* no emulation for low level handles */ + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.h new file mode 100755 index 00000000..dd27053f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.h @@ -0,0 +1,39 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_CONTROL_PD_H +#define _G2_CONTROL_PD_H + +#include "g2_physical_device.h" + +void g2_flush_pd(g2_physical_device *pd); +void g2_save_pd(g2_physical_device *pd); +void g2_clear_pd(g2_physical_device *pd); +void g2_pen_pd(g2_physical_device *pd, int color); +void g2_set_background_pd(g2_physical_device *pd, int color); +int g2_ink_pd(g2_physical_device *pd, double red, double green, double blue); +void g2_clear_palette_pd(g2_physical_device *pd); +void g2_allocate_basic_colors_pd(g2_physical_device *pd); +void g2_set_font_size_pd(g2_physical_device *pd, double size); +void g2_set_line_width_pd(g2_physical_device *pd, double w); +void g2_set_dash_pd(g2_physical_device *pd, int N, double *dashes); +void g2_query_pointer_pd(g2_physical_device *pd, + double *x, double *y, unsigned int *button); +void g2_get_pd_handles_pd(g2_physical_device *pd, void *handles[G2_PD_HANDLES_SIZE]); + +#endif /* _G2_CONTROL_PD_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_control_pd.o new file mode 100755 index 0000000000000000000000000000000000000000..e88605c563fe50e082bc32cd6e5bbab648ab047d GIT binary patch literal 9960 zcmbta4Rn;%nZDmQGntQMmiBohdS((n_|3LPeyNiyqXCQfGf zaY3sQbsSOf*dG6OSNGTL_Q!6iSl4djQboEwU8>z(C`NIsrzp{8do0IREc-n7d%w&C z(A_W!wzHRH(yMC^JmMi zzL@;#3*@UDd#Xh~=z~4hShK2iH*L?TeC_AR*V^*WpF`oK=jOg(<<|NJZmUq4acDa* zoAVnARu65itr`ke07{2~K7f^5X8XgSKh{-TVDG5^uDICzt{5YK{KM?Kn~tA4eq`hN zf#J=$pf%L~>hU9ogGV`fuFZEi_;aOB-Z0dDEVrs+&ykF8=-AM)fgf$Y`OBd#hlV!P 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z&Ia(YRlsnn{ERBp_c0v6VX2Sk=<7h;>4U0zV1iQV0*2$4FQctcA1{kX!J|I>x;d&3 zpAuvA@z0Ah3-meFB;*S99fdx}KK}ga*mv)F`etIl8t|Or=o2Q;u_tpPJ2P1gXPkZlJDSBT<5alz9L2g?o0 zP?rF?whlcP^{oYTBkKF`@SBP9+;@Wo^m^1s@U-AzJAbHL3a2^xZUyap6S19N+s-!- z>8C+Eh1UNK9_KrV?f(ec`Sv0GV@H^Bcz%8!{RU~c`7nU;w9P4$|2-b(8;I>ZhQ@rz zgC4#16`W=ib3S`e&!3JwNH4fU-~2|gtFxZqz1en)Un@LvVr6#PK&tY8U3hU4+i0mRD$7YVKq+$hLzcFOULAPxvV zEcmqGvw}Yq{HfrO;IQB)g2nJ9_3;k|#0J47g3W^K1h)!4E%*&V{waX{Ul1G=d`0jl zg0Bf46MR$f9l`enM+DCZo)zRD9ypFAsDC#FT_N-o!5YEYf>#JG5L_h4zxhyKv*0Sh zHo=X8n*}=rdju1L8Ns^+9}s+4@G-$>1cwBN1xpe4v?DB-6x=PC6MRbWMZrTv_=Z17 z5>E>MS3;i_bYm}3e+dzC0YUyHj{JI|7Yeor|0cn$!jA~@Z-eZ2zu;Ge|Cr$Sh5w4+ zyMn{gJ|Z{{8=ZPeiLk3eFfROlp|=a(FZ}Ncz99U668u>B=Y)14cTn#PBF5P&*dzS7 z;G@ESU+_1=KOwx#J_3(F@^HNQM9@0_fL + +#include "g2.h" +#include "g2_device.h" +#include "g2_physical_device.h" +#include "g2_virtual_device.h" +#include "g2_util.h" + +int __g2_last_device=-1; /* last acces. device (ld) */ + + +static int g2_dev_size=0; /* size of devices array */ +static g2_device *g2_dev=NULL; /* devices array */ + +static int g2_get_free_device(); +static void g2_init_device(int dix); + + +/* + * + * Register physical device + * + */ +int g2_register_physical_device(int pid, + void *pdp, + g2_coor ct, + const g2_funix_fun *ff, + double a11, double a22, + double b1, double b2) +{ + int dix; + + dix=g2_get_free_device(); + g2_init_device(dix); + g2_dev[dix].t=g2_PD; + g2_dev[dix].d.pd=g2_create_physical_device(pid, pdp, + ct, ff, + a11, a22, + b1, b2); + + __g2_last_device=dix; + return dix; +} + + + +/* + * + * Register virtual device + * + */ +int g2_register_virtual_device() +{ + int dix; + + dix=g2_get_free_device(); + g2_init_device(dix); + g2_dev[dix].t=g2_VD; + g2_dev[dix].d.vd=g2_create_virtual_device(); + + return dix; +} + + +/* + * + * Init device + * + */ +void g2_init_device(int dix) +{ + g2_dev[dix].t=g2_ILLEGAL; + g2_dev[dix].dix=dix; + g2_dev[dix].x=0.0; /* set cursor */ + g2_dev[dix].y=0.0; + g2_dev[dix].auto_flush=1; /* set auto flush */ + g2_dev[dix].QPd=1.0; /* Quasi pixel spec. */ + g2_dev[dix].QPshape=QPrect; +} + +/* + * + * Return pointer to device dix + * + */ +g2_device *g2_get_device_pointer(int dix) +{ + if(dix<0 || dix>=g2_dev_size) + return NULL; + if(g2_dev[dix].t==g2_NDEV) + return NULL; + + return &g2_dev[dix]; +} + + +/* + * + * Return device type + * + */ +g2_device_type g2_get_device_type(int dix) +{ + if(dix<0 || dix>=g2_dev_size) + return g2_ILLEGAL; + return g2_dev[dix].t; +} + + +/* + * + * 1 if device exist otherwise 0 + * + */ +int g2_device_exist(int dix) +{ + if(dix<0 || dix>=g2_dev_size || + g2_dev[dix].t==g2_ILLEGAL || g2_dev[dix].t==g2_NDEV) + return 0; + return 1; +} + + +/* + * + * Destroy device + * + */ +void g2_destroy_device(int dix) +{ + int i; + + for(i=0;id0m2d>UU~rKT?|4J$WgICAc#R;ue4Xvj#s;y-Md(# z5U^#iH;N2N?bLPMG=yg2q{+mI@hh>%0=ZyMJZTF_gF_%5YEN;XjqAFEiE-%npZnk4 zl^~g(nZ4inpXdM2IsdtjJ`0bMs1(Jbz*UvFeJGc3xbWb+ z|CRh;xUl8qWi?sv(_bMc7q|IxF7EafzIz3%(%O+Ty6+YmSY=>TwvQ&SZ%=+OwB0y# 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HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_fif.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_fif.c new file mode 100755 index 00000000..6772cf48 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_fif.c @@ -0,0 +1,499 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include "g2.h" +#include "g2_util.h" + +/* + * + * g2 Fortran Interface + * + */ +#ifdef LINUX +#define FIF(funame) funame ## __ +#else +#define FIF(funame) funame ## _ +#endif + +#define F_REAL float /* everything is float (real) !!!!!!!!!!!!!! */ +#define F_CHAR char /* only char is char */ +#define F_CHAR_LENGTH int /* and char length is integer (it is automatically supplied */ + + +/**********************************************************/ + +#ifdef DO_PS + +#include "PS/g2_PS.h" + + + + + +F_REAL FIF(g2_open_ps)(F_CHAR *text, F_REAL *paper, F_REAL *orientation, + F_CHAR_LENGTH length) +{ + char *str; + int rv; + + str=g2_malloc((length+1)*sizeof(char)); + strncpy(str, text, length); + str[length]='\0'; + rv=g2_open_PS(str, dtoi(*paper), dtoi(*orientation)); + g2_free(str); + + return (F_REAL)rv; +} + +#endif /* DO_PS */ + +/**********************************************************/ + +#ifdef DO_X11 + +#include "X11/g2_X11.h" + +F_REAL FIF(g2_open_x11)(F_REAL *width, F_REAL *height) +{ + return (F_REAL)g2_open_X11(*width, *height); +} + +/* g2_open_x11x is missing */ + +#endif /* DO_X11 */ + +/**********************************************************/ + +#ifdef DO_GD + +#include "GD/g2_gd.h" + +F_REAL FIF(g2_open_gd)(F_CHAR *text, F_REAL *width, F_REAL *height, F_REAL *gd_type, + F_CHAR_LENGTH length) +{ + char *str; + int rv; + + str=g2_malloc((length+1)*sizeof(char)); + strncpy(str, text, length); + str[length]='\0'; + + rv=g2_open_gd(str, *width, *height, *gd_type); + + g2_free(str); + + return (F_REAL)rv; +} + +#endif /* DO_GD */ + +/**********************************************************/ + + +F_REAL FIF(g2_open_vd)(void) +{ + return (F_REAL)g2_open_vd(); +} + + +void FIF(g2_attach)(F_REAL *vd_dev, F_REAL *dev) +{ + g2_attach(dtoi(*vd_dev), dtoi(*dev)); +} + + +void FIF(g2_detach)(F_REAL *vd_dev, F_REAL *dev) +{ + g2_detach(dtoi(*vd_dev), dtoi(*dev)); +} + + + +void FIF(g2_close)(F_REAL *dev) +{ + g2_close(dtoi(*dev)); +} + + +void FIF(g2_set_auto_flush)(F_REAL *dev, F_REAL *on_off) +{ + g2_set_auto_flush(dtoi(*dev), dtoi(*on_off)); +} + + +void FIF(g2_set_coordinate_system)(F_REAL *dev, + F_REAL *x_origin, F_REAL *y_origin, + F_REAL *x_mul, F_REAL *y_mul) +{ + g2_set_coordinate_system(dtoi(*dev), + *x_origin, *y_origin, + *x_mul, *y_mul); +} + + +F_REAL FIF(g2_ld)(void) +{ + return (F_REAL)g2_ld(); +} + + +void FIF(g2_set_ld)(F_REAL *dev) +{ + g2_set_ld(dtoi(*dev)); +} + + + +void FIF(g2_flush)(F_REAL *dev) +{ + g2_flush(dtoi(*dev)); +} + + +void FIF(g2_save)(F_REAL *dev) +{ + g2_save(dtoi(*dev)); +} + + + + +void FIF(g2_arc)(F_REAL *dev, F_REAL *x, F_REAL *y, + F_REAL *r1, F_REAL *r2, F_REAL *a1, F_REAL *a2) +{ + g2_arc(dtoi(*dev), *x, *y, *r1, *r2, *a1, *a2); +} + + +void FIF(g2_circle)(F_REAL *dev, F_REAL *x, F_REAL *y, F_REAL *r) +{ + g2_circle(dtoi(*dev), *x, *y, *r); +} + + +void FIF(g2_clear)(F_REAL *dev) +{ + g2_clear(dtoi(*dev)); +} + + +void FIF(g2_clear_palette)(F_REAL *dev) +{ + g2_clear_palette(dtoi(*dev)); +} + + +void FIF(g2_string)(F_REAL *dev, F_REAL *x, F_REAL *y, F_CHAR *text, + F_CHAR_LENGTH length) +{ + char *str; + str=g2_malloc((length+1)*sizeof(char)); + strncpy(str, text, length); + str[length]='\0'; + g2_string(dtoi(*dev), *x, *y, str); + g2_free(str); +} + + +void FIF(g2_ellipse)(F_REAL *dev, F_REAL *x, F_REAL *y, F_REAL *r1, F_REAL *r2) +{ + g2_ellipse(dtoi(*dev), *x, *y, *r1, *r2); +} + + +void FIF(g2_filled_arc)(F_REAL *dev, F_REAL *x, F_REAL *y, + F_REAL *r1, F_REAL *r2, + F_REAL *a1, F_REAL *a2) +{ + g2_filled_arc(dtoi(*dev), *x, *y, *r1, *r2, *a1, *a2); +} + + +void FIF(g2_filled_circle)(F_REAL *dev, F_REAL *x, F_REAL *y, F_REAL *r) +{ + g2_filled_circle(dtoi(*dev), *x, *y, *r); +} + + +void FIF(g2_filled_ellipse)(F_REAL *dev, F_REAL *x, F_REAL *y, F_REAL *r1, F_REAL *r2) +{ + g2_filled_ellipse(dtoi(*dev), *x, *y, *r1, *r2); +} + + +void FIF(g2_filled_triangle)(F_REAL *dev, F_REAL *x1, F_REAL *y1, + F_REAL *x2, F_REAL *y2, + F_REAL *x3, F_REAL *y3) +{ + g2_filled_triangle(dtoi(*dev), *x1, *y1, *x2, *y2, *x3, *y3); +} + + +F_REAL FIF(g2_ink)(F_REAL *dev, F_REAL *red, F_REAL *green, F_REAL *blue) +{ + return (F_REAL)g2_ink(dtoi(*dev), *red, *green, *blue); +} + + +void FIF(g2_line)(F_REAL *dev, F_REAL *x1, F_REAL *y1, F_REAL *x2, F_REAL *y2) +{ + g2_line(dtoi(*dev), *x1, *y1, *x2, *y2); +} + + +void FIF(g2_poly_line)(F_REAL *dev, F_REAL *N_pt, F_REAL *points) +{ + double *d; + d=g2_floatp2doublep(points, dtoi(*N_pt)*2); + g2_poly_line(dtoi(*dev), dtoi(*N_pt), d); + g2_free(d); +} + + +void FIF(g2_polygon)(F_REAL *dev, F_REAL *N_pt, F_REAL *points) +{ + double *d; + d=g2_floatp2doublep(points, dtoi(*N_pt)*2); + g2_polygon(dtoi(*dev), dtoi(*N_pt), d); + g2_free(d); +} + + +void FIF(g2_filled_polygon)(F_REAL *dev, F_REAL *N_pt, F_REAL *points) +{ + double *d; + d=g2_floatp2doublep(points, dtoi(*N_pt)*2); + g2_filled_polygon(dtoi(*dev), dtoi(*N_pt), d); + g2_free(d); +} + + +void FIF(g2_line_r)(F_REAL *dev, F_REAL *dx, F_REAL *dy) +{ + g2_line_r(dtoi(*dev), *dx, *dy); +} + + +void FIF(g2_line_to)(F_REAL *dev, F_REAL *x, F_REAL *y) +{ + g2_line_to(dtoi(*dev), *x, *y); +} + + +void FIF(g2_move)(F_REAL *dev, F_REAL *x, F_REAL *y) +{ + g2_move(dtoi(*dev), *x, *y); +} + + +void FIF(g2_move_r)(F_REAL *dev, F_REAL *dx, F_REAL *dy) +{ + g2_move_r(dtoi(*dev), *dx, *dy); +} + + +void FIF(g2_pen)(F_REAL *dev, F_REAL *color) +{ + g2_pen(dtoi(*dev), dtoi(*color)); +} + + +void FIF(g2_plot)(F_REAL *dev, F_REAL *x, F_REAL *y) +{ + g2_plot(dtoi(*dev), *x, *y); +} + + +void FIF(g2_plot_r)(F_REAL *dev, F_REAL *dx, F_REAL *dy) +{ + g2_plot_r(dtoi(*dev), *dx, *dy); +} + + +void FIF(g2_rectangle)(F_REAL *dev, + F_REAL *x1, F_REAL *y1, + F_REAL *x2, F_REAL *y2) +{ + g2_rectangle(dtoi(*dev), *x1, *y1, *x2, *y2); +} + + +void FIF(g2_filled_rectangle)(F_REAL *dev, + F_REAL *x1, F_REAL *y1, + F_REAL *x2, F_REAL *y2) +{ + g2_filled_rectangle(dtoi(*dev), *x1, *y1, *x2, *y2); +} + + +void FIF(g2_reset_palette)(F_REAL *dev) +{ + g2_reset_palette(dtoi(*dev)); +} + + +void FIF(g2_set_background)(F_REAL *dev, F_REAL *color) +{ + g2_set_background(dtoi(*dev), dtoi(*color)); +} + + +void FIF(g2_set_dash)(F_REAL *dev, F_REAL *N, F_REAL *dashes) +{ + double *d; + d=g2_floatp2doublep(dashes, dtoi(*N)); + g2_set_dash(dtoi(*dev), dtoi(*N), d); + g2_free(d); +} + + +void FIF(g2_set_font_size)(F_REAL *dev, F_REAL *size) +{ + g2_set_font_size(dtoi(*dev), *size); +} + + +void FIF(g2_set_line_width)(F_REAL *dev, F_REAL *w) +{ + g2_set_line_width(dtoi(*dev), *w); +} + + +void FIF(g2_triangle)(F_REAL *dev, F_REAL *x1, F_REAL *y1, + F_REAL *x2, F_REAL *y2, + F_REAL *x3, F_REAL *y3) +{ + g2_triangle(dtoi(*dev), *x1, *y1, *x2, *y2, *x3, *y3); +} + + +void FIF(g2_set_qp)(F_REAL *dev, F_REAL *d, F_REAL *shape) +{ + g2_set_QP(dtoi(*dev), *d, dtoi(*shape)); +} + + +void FIF(g2_plot_qp)(F_REAL *dev, F_REAL *x, F_REAL *y) +{ + g2_plot_QP(dtoi(*dev), *x, *y); +} + + +/* thanks to Yuri Sbitnev for contributing the g2_image code for FORTRAN */ +void FIF(g2_image)(F_REAL *dev, F_REAL *x, F_REAL *y, F_REAL *x_size, F_REAL *y_size, + F_REAL *pens) +{ + int i, j, xs, ys; + int *mypens; + xs=dtoi(*x_size); + ys=dtoi(*y_size); + mypens=(int *) g2_malloc(xs*ys*sizeof(int)); + for(j=0;jx&5s?=hQN=vVA<$mA!_xb0{5TtkMz00-Qf33-P zzPlYI;%jQ{o8iBuvS_ETrLyq#b4q$Lk&i?n z6CIK0xYLJDLBj2WZCekl@1ffBQ1$ud`r%piDQ5IN5p;hhijXK_;-9Rc42K8$$apxg zy>#n*eKW0FbN8`c{;%)PL)U+J^W1-+iY;@CnwNiperZ`=*j&CB??Q8BYjfi#&EZvdxC3R^1oK!6Tzscg;cG|>7u5Vuq(w4@K7{VOLbMrBZcecX__Qqq+5@(Ay z&qMXNr@<7z*P043wwGaPFw;@<@&kveym%So^ 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z==uupFUb7{<&}bSMII4s68SF#x&NTw+XWvL`3}KdBHu080qYL^hlt46U66NQl&=!L zTJScJKO(qI|ChUN9a`c5n(qTC^ZlSDpS@KV9mqF*O?v&iojmuPjg%1=yRQM#}Q-w!`FBHB^_zL0I3*RJs zi||Ksdw<~rh0hdzx^VuV6xuHqevR=0), <0 if error */ + + g2_Pen, /* set pen */ + /* ... = (int)pen */ + + g2_SetBackground, /* set background */ + /* ... = (int)pen */ + + g2_ClearPalette, /* reset color pallete to default values */ + /* ... = */ + /* for list of default colors (0,31) see later */ + + g2_SetLineWidth, /* set line width (line, rectangle, ...) */ + /* ... = (double)line width */ + + g2_SetDash, /* set line dash */ + /* ... = (int)number of descr., (double*) bw list */ + + g2_SetFontSize, /* set font size */ + /* ... = (double)font size */ + + g2_Clear, /* clear screen(X11), print page(PostScript), ... */ + /* ... = */ + + g2_Flush, /* update output */ + /* X11: Flush, PostScript: fflush, ... */ + + g2_Save, /* save output to device (e.g. file) */ + /* X11: Flush, etc. */ + + g2_Plot, /* plot point */ + /* ... = (double)x, (double)y */ + + g2_Line, /* draw line */ + /* ... = (double)x1, (double)y1, + (double)x2, (double)y2 */ + + g2_PolyLine, /* draw poly line */ + /* ... = (int)N, + (double*)dp + dp[0]=x1, dp[1]=y1, + ... + dp[2*N-2]=xN, dp[2*N-1]=yN */ + + g2_Polygon, /* draw polygon */ + /* ... = (int)N, + (double*)dp + dp[0]=x1, dp[1]=y1, + ... + dp[2*N-2]=xN, dp[2*N-1]=yN */ + + g2_FilledPolygon, /* draw filled polygon */ + /* ... = (int)N, + (double*)dp + dp[0]=x1, dp[1]=y1, + ... + dp[2*N-2]=xN, dp[2*N-1]=yN */ + + g2_Rectangle, /* draw rectangle */ + /* ... = (double)x1, (double)y1, + (double)x2, (double)y2 */ + + g2_FilledRectangle, /* draw filled rectangle */ + /* ... = (double)x1, (double)x1, + (double)x2, (double)y2 */ + + g2_Triangle, /* draw triangle (should be faster as lines) */ + /* ... = (double)x1, (double)y1, + (double)x2, (double)y2, + (double)x3, (double)y3 */ + + g2_FilledTriangle, /* draw filled triangle */ + /* ... = (double)x1, (double)y1, + (double)x2, (double)y2, + (double)x3, (double)y3 */ + + g2_Arc, /* draw arc */ + /* ... = (double)x, (double)y, + (double)r1, (double)r2, + (double)a1, (double)a2 */ + + g2_FilledArc, /* draw filled arc */ + /* ... = (double)x, (double)y, + (double)r1, (double)r2, + (double)a1, (double)a2 */ + + g2_Ellipse, /* draw ellipse */ + /* ... = (double)x, (double)y, + (double)r1, (double)r2 */ + + g2_FilledEllipse, /* draw filled ellipse */ + /* ... = (double)x, (double)y, + (double)r1, (double)r2 */ + + g2_Circle, /* draw circle */ + /* ... = (double)x, (double)y, + (double)r */ + + g2_FilledCircle, /* draw filled circle */ + /* ... = (double)x, (double)y, + (double)r */ + + g2_String, /* draw string */ + /* ... = (double)x, (double)y, (const char*)string */ + + g2_Image, /* draw (pen) image */ + /* ... = (double)x, (double)y, + (int)x_size, (int)y_size, (int*)pen_array */ + + g2_QueryPointer, /* query pointer position (mouse) */ + /* ... = (double)*x, (double)*y, + (unsigned int)*button */ + g2_GetPDHandles /* get pointers to low level handles */ + /* ... = void *handles[G2_MAX_NUMBER_PD_HANDLES] */ +} g2_funix; + + +#endif /* _G2_FUNIX_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_graphic_pd.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_graphic_pd.c new file mode 100755 index 00000000..db4a6f85 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_graphic_pd.c @@ -0,0 +1,684 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include + +#include "g2_funix.h" +#include "g2_virtual_device.h" +#include "g2_graphic_pd.h" +#include "g2_control_pd.h" +#include "g2_util.h" + +#ifndef PI +#define PI 3.14159265358979323846 +#endif /* PI */ + + +/* + * + * Plot (physical device) + * + */ +void g2_plot_pd(g2_physical_device *pd, double x, double y) +{ + int ix, iy; + double dx, dy; + + if(pd->ff[g2_Plot].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + pd->ff[g2_Plot].fun(pd->pid, pd->pdp, + ix, iy); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + pd->ff[g2_Plot].fun(pd->pid, pd->pdp, + dx, dy); + break; + } + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Draw line (low_level) + * + */ +void g2_line_pd(g2_physical_device *pd, + double x1, double y1, double x2, double y2) +{ + int ix1, iy1, ix2, iy2; + double dx1, dy1, dx2, dy2; + + if(pd->ff[g2_Line].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x1, y1, &ix1, &iy1); + g2_uc2pdc_int(pd, x2, y2, &ix2, &iy2); + pd->ff[g2_Line].fun(pd->pid, pd->pdp, + ix1, iy1, ix2, iy2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x1, y1, &dx1, &dy1); + g2_uc2pdc_double(pd, x2, y2, &dx2, &dy2); + pd->ff[g2_Line].fun(pd->pid, pd->pdp, + dx1, dy1, dx2, dy2); + break; + } + } else { + /* emulate ... with .... */ + } +} + + + +/* + * + * Draw poly line (physical device) + * + */ +void g2_poly_line_pd(g2_physical_device *pd, + int N, double *points) +{ + int i; + int *ipt; + double *dpt; + + if(pd->ff[g2_PolyLine].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + ipt=g2_malloc(2*N*sizeof(int)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_int(pd, points[i+0], points[i+1], ipt+i, ipt+i+1); + pd->ff[g2_PolyLine].fun(pd->pid, pd->pdp, + N, ipt); + free(ipt); + break; + case g2_DoubleCoor: + dpt=g2_malloc(2*N*sizeof(double)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_double(pd, + points[i+0], points[i+1], + dpt+i, dpt+i+1); + pd->ff[g2_PolyLine].fun(pd->pid, pd->pdp, + N, dpt); + free(dpt); + break; + } + } else { + for (i=0;iff[g2_Triangle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x1, y1, &ix1, &iy1); + g2_uc2pdc_int(pd, x2, y2, &ix2, &iy2); + g2_uc2pdc_int(pd, x3, y3, &ix3, &iy3); + pd->ff[g2_Triangle].fun(pd->pid, pd->pdp, + ix1, iy1, + ix2, iy2, + ix3, iy3); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x1, y1, &dx1, &dy1); + g2_uc2pdc_double(pd, x2, y2, &dx2, &dy2); + g2_uc2pdc_double(pd, x3, y3, &dx3, &dy3); + pd->ff[g2_Triangle].fun(pd->pid, pd->pdp, + dx1, dy1, + dx2, dy2, + dx3, dy3); + } + } else { + g2_line_pd(pd, x1, y1, x2, y2); /* emulate triangle with lines */ + g2_line_pd(pd, x2, y2, x3, y3); + g2_line_pd(pd, x3, y3, x1, y1); + } +} + + + +/* + * + * Filled triangle (physical device) + * + */ +void g2_filled_triangle_pd(g2_physical_device *pd, + double x1, double y1, + double x2, double y2, + double x3, double y3) +{ + int ix1, iy1, ix2, iy2, ix3, iy3; + double dx1, dy1, dx2, dy2, dx3, dy3; + + if(pd->ff[g2_FilledTriangle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x1, y1, &ix1, &iy1); + g2_uc2pdc_int(pd, x2, y2, &ix2, &iy2); + g2_uc2pdc_int(pd, x3, y3, &ix3, &iy3); + pd->ff[g2_FilledTriangle].fun(pd->pid, pd->pdp, + ix1, iy1, + ix2, iy2, + ix3, iy3); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x1, y1, &dx1, &dy1); + g2_uc2pdc_double(pd, x2, y2, &dx2, &dy2); + g2_uc2pdc_double(pd, x3, y3, &dx3, &dy3); + pd->ff[g2_FilledTriangle].fun(pd->pid, pd->pdp, + dx1, dy1, + dx2, dy2, + dx3, dy3); + } + } else { + double Triangle[6]; /* emulate FilledTriangle with FilledPolygon */ + Triangle[0] = x1; + Triangle[1] = y1; + Triangle[2] = x2; + Triangle[3] = y2; + Triangle[4] = x3; + Triangle[5] = y3; + g2_filled_polygon_pd(pd, 3, Triangle); + } +} + + + +/* + * + * Rectangle (physical device) + * + */ +void g2_rectangle_pd(g2_physical_device *pd, + double x1, double y1, double x2, double y2) +{ + int ix1, iy1, ix2, iy2; + double dx1, dy1, dx2, dy2; + + if(pd->ff[g2_Rectangle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x1, y1, &ix1, &iy1); + g2_uc2pdc_int(pd, x2, y2, &ix2, &iy2); + g2_sort2_i(&ix1, &ix2); + g2_sort2_i(&iy1, &iy2); + pd->ff[g2_Rectangle].fun(pd->pid, pd->pdp, + ix1, iy1, ix2, iy2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x1, y1, &dx1, &dy1); + g2_uc2pdc_double(pd, x2, y2, &dx2, &dy2); + g2_sort2_d(&dx1, &dx2); + g2_sort2_d(&dy1, &dy2); + pd->ff[g2_Rectangle].fun(pd->pid, pd->pdp, + dx1, dy1, dx2, dy2); + break; + } + } else { + g2_line_pd(pd, x1, y1, x1, y2); /* emulate rectangle with lines */ + g2_line_pd(pd, x1, y1, x2, y1); + g2_line_pd(pd, x2, y1, x2, y2); + g2_line_pd(pd, x1, y2, x2, y2); + } +} + + + +/* + * + * Filled rectangle (physical device) + * + */ +void g2_filled_rectangle_pd(g2_physical_device *pd, + double x1, double y1, double x2, double y2) +{ + int ix1, iy1, ix2, iy2; + double dx1, dy1, dx2, dy2; + + if(pd->ff[g2_FilledRectangle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x1, y1, &ix1, &iy1); + g2_uc2pdc_int(pd, x2, y2, &ix2, &iy2); + g2_sort2_i(&ix1, &ix2); + g2_sort2_i(&iy1, &iy2); + pd->ff[g2_FilledRectangle].fun(pd->pid, pd->pdp, + ix1, iy1, ix2, iy2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x1, y1, &dx1, &dy1); + g2_uc2pdc_double(pd, x2, y2, &dx2, &dy2); + g2_sort2_d(&dx1, &dx2); + g2_sort2_d(&dy1, &dy2); + pd->ff[g2_FilledRectangle].fun(pd->pid, pd->pdp, + dx1, dy1, dx2, dy2); + break; + } + } else { + double Rectangle[8]; /* emulate FilledRectangle with FilledPolygon */ + Rectangle[0] = x1; + Rectangle[1] = y1; + Rectangle[2] = x2; + Rectangle[3] = y1; + Rectangle[4] = x2; + Rectangle[5] = y2; + Rectangle[6] = x1; + Rectangle[7] = y2; + g2_filled_polygon_pd(pd,4,Rectangle); + } +} + + + +/* + * + * Polygon (physical device) + * + */ +void g2_polygon_pd(g2_physical_device *pd, + int N, double *points) +{ + int i; + int *ipt; + double *dpt; + + if(pd->ff[g2_Polygon].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + ipt=g2_malloc(2*N*sizeof(int)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_int(pd, points[i+0], points[i+1], ipt+i, ipt+i+1); + pd->ff[g2_Polygon].fun(pd->pid, pd->pdp, + N, ipt); + free(ipt); + break; + case g2_DoubleCoor: + dpt=g2_malloc(2*N*sizeof(double)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_double(pd, + points[i+0], points[i+1], dpt+i, dpt+i+1); + pd->ff[g2_Polygon].fun(pd->pid, pd->pdp, + N, dpt); + free(dpt); + break; + } + } else { + for (i=0;iff[g2_FilledPolygon].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + ipt=g2_malloc(2*N*sizeof(int)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_int(pd, points[i+0], points[i+1], ipt+i, ipt+i+1); + pd->ff[g2_FilledPolygon].fun(pd->pid, pd->pdp, + N, ipt); + free(ipt); + break; + case g2_DoubleCoor: + dpt=g2_malloc(2*N*sizeof(double)); + for(i=0;i<2*N;i+=2) + g2_uc2pdc_double(pd, + points[i+0], points[i+1], dpt+i, dpt+i+1); + pd->ff[g2_FilledPolygon].fun(pd->pid, pd->pdp, + N, dpt); + free(dpt); + break; + } + } else { + /* emulate filled polygon with .... */ + } +} + + + +/* + * + * Ellipse (physical device) + * + */ +void g2_ellipse_pd(g2_physical_device *pd, + double x, double y, double r1, double r2) +{ + int ix, iy, ir1, ir2; + double dx, dy, dr1, dr2; + + if(pd->ff[g2_Ellipse].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r1, r2, &ir1, &ir2); + pd->ff[g2_Ellipse].fun(pd->pid, pd->pdp, + ix, iy, ir1, ir2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r1, r2, &dr1, &dr2); + pd->ff[g2_Ellipse].fun(pd->pid, pd->pdp, + dx, dy, dr1, dr2); + break; + } + } else { + g2_arc_pd(pd, x, y, r1, r2, 0., 360.); /* emulate ellipse with arc */ + } +} + + + +/* + * + * Filled ellipse (physical device) + * + */ +void g2_filled_ellipse_pd(g2_physical_device *pd, + double x, double y, double r1, double r2) +{ + int ix, iy, ir1, ir2; + double dx, dy, dr1, dr2; + + if(pd->ff[g2_FilledEllipse].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r1, r2, &ir1, &ir2); + pd->ff[g2_FilledEllipse].fun(pd->pid, pd->pdp, + ix, iy, ir1, ir2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r1, r2, &dr1, &dr2); + pd->ff[g2_FilledEllipse].fun(pd->pid, pd->pdp, + dx, dy, dr1, dr2); + break; + } + } else { + g2_filled_arc_pd(pd, /* emulate filledellipse with filled arc */ + x, y, + r1, r2, + 0., 360.); + } +} + + + +/* + * + * Circle (physical device) + * + */ +void g2_circle_pd(g2_physical_device *pd, + double x, double y, double r) +{ + int ix, iy, ir; + double dx, dy, dr; + + if(pd->ff[g2_Circle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r, 0, &ir, NULL); + pd->ff[g2_Circle].fun(pd->pid, pd->pdp, + ix, iy, ir); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r, 0, &dr, NULL); + pd->ff[g2_Circle].fun(pd->pid, pd->pdp, + dx, dy, dr); + break; + } + } else { + g2_ellipse_pd(pd, x, y, r, r); /* emulate circle with ellipse */ + } +} + + + +/* + * + * Filled circle (physical device) + * + */ +void g2_filled_circle_pd(g2_physical_device *pd, + double x, double y, double r) +{ + int ix, iy, ir; + double dx, dy, dr; + + if(pd->ff[g2_FilledCircle].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r, 0, &ir, NULL); + pd->ff[g2_FilledCircle].fun(pd->pid, pd->pdp, + ix, iy, ir); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r, 0, &dr, NULL); + pd->ff[g2_FilledCircle].fun(pd->pid, pd->pdp, + dx, dy, dr); + break; + } + } else { + g2_filled_ellipse_pd(pd, x, y, r, r); /* emulate */ + } +} + + + +/* + * + * Arc (physical device) + * + */ +void g2_arc_pd(g2_physical_device *pd, + double x, double y, double r1, double r2, double a1, double a2) +{ + int ix, iy, ir1, ir2; + double dx, dy, dr1, dr2; + + if(pd->ff[g2_Arc].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r1, r2, &ir1, &ir2); + pd->ff[g2_Arc].fun(pd->pid, pd->pdp, + ix, iy, ir1, ir2, a1, a2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r1, r2, &dr1, &dr2); + pd->ff[g2_Arc].fun(pd->pid, pd->pdp, + dx, dy, dr1, dr2, a1, a2); + break; + } + } else { + double a, da, *pt; /* emulate arc */ + int N, i; + N=(a2==a1)?360:(int)fabs(a2-a1)+8; + a=a1*2.*PI/360.; + da=((a2>a1)? (a2-a1):360.-(a1-a2))*2.*PI/360./(N-1); + pt=g2_malloc(2*N*sizeof(double)); + for(i=0;iff[g2_FilledArc].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + g2_us2pds_int(pd, r1, r2, &ir1, &ir2); + pd->ff[g2_FilledArc].fun(pd->pid, pd->pdp, + ix, iy, ir1, ir2, a1, a2); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + g2_us2pds_double(pd, r1, r2, &dr1, &dr2); + pd->ff[g2_FilledArc].fun(pd->pid, pd->pdp, + dx, dy, dr1, dr2, a1, a2); + break; + } + } else { + double a, da, *pt; /* emulate filled arc */ + int N, i; + N=(a2==a1)?360:(int)fabs(a2-a1)+8; + a=a1*2.*PI/360.; + da=((a2>a1)? (a2-a1):360.-(a1-a2))*2.*PI/360./(N-1); + pt=g2_malloc(2*(N+2)*sizeof(double)); + pt[0]=x; + pt[1]=y; + for(i=0;iff[g2_String].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + pd->ff[g2_String].fun(pd->pid, pd->pdp, + ix, iy, text); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + pd->ff[g2_String].fun(pd->pid, pd->pdp, + dx, dy, text); + break; + } + } else { + /* emulate ... with .... */ + } +} + + + +void g2_image_pd(g2_physical_device *pd, + double x, double y, int x_size, int y_size, int *pens) +{ + int ix, iy; + double dx, dy; + + if(pd->ff[g2_Image].fun!=NULL) { + switch(pd->coor_type) { + case g2_IntCoor: + g2_uc2pdc_int(pd, x, y, &ix, &iy); + pd->ff[g2_Image].fun(pd->pid, pd->pdp, + ix, iy, x_size, y_size, pens); + break; + case g2_DoubleCoor: + g2_uc2pdc_double(pd, x, y, &dx, &dy); + pd->ff[g2_Image].fun(pd->pid, pd->pdp, + dx, dy, x_size, y_size, pens); + break; + } + } else { + for(ix=0;ixICYrCsgEepPF`bfrpLx26^GPy2LPbyrv!3zqL&qG^p?>)L8{f4_Urop~n& zb@%DBU%&Tp=G@=C=bn4+x#ygF?>oVrp_R)V$5HliluxCQQY}}Rmf4z2QDfC;%c^Nb z=l@yN(YG{S8Ayb(6QR6#X?A>Zcy~{9XuLE45-f|BCypnMcN|%|zVhkLcM~@hXLp6( z>0DZz-xcZy$wQ65v#|K=2OoX(Q9Sfcd{s7Tv*Wrk5HIxu`QyG$fAL4xhm8~?vj1D*Yk0=Z7x*dFG4q?pU z#PihnoH=CMIdp~kjAm3YFA*xHx`|LB+SyU&*=OdN7Y~sw2NMSweAbN}M>sCUbcHxw zSnjx%?Xg@}=$L7FPPYs?Y9e&ZSf(fudJf|9je%gN<3I!K)Yv-=cG?U3tX+c@UKkH$ z$8QP5D{?wR{qg15ofUoYvgq#Tqod=?xz6igr`KVpjw1`#-&j@oG}f=I<2`ljTk*=i z&ZAvhl-N5_nvbyx6QwyId5O{hNOr>4@pMk-!jyfkjlJR#H1pjbpP~b3({*BbL;X$< zg)iw0or+hU?RuOm+4U5^J0Z2J)Zg)RfaZvY`Vvd~%^3dvj-#%3ka@9FJCDUH&T=-Z zVf%`HkU)H`AH*LY)0tQNQF)Z>6AFkjy~aoTsgOUV(3zw{b2>vOo6J z--r^wIY)_;RN~AhC~>BD3swVWq`%(Qw+l0c%QD#7_oKYKC%EfH*6Enb!CK5i5Z`u$ zd~lrs&KhFO!6oUkC>fXhG;Z4!I%Ay71YKyhku%LJCmuRuT)QxCoE2+8m;7W$-^ZDx zbUt)3pfd4Oi1@)+h^E0*PiRHJGtKY}7ICI0c$gU=XE4=MW9#@rm@%f#GiXD|O!NHd%GJE9Hd+49;CXrl&q{fsR- z3P-`P8Hhse9Jd`|4@BZ#yL%k*IuD{TwR=2iTIf0F**&^KhYZihxK%uKC>e%iLn@?T zgdqiEzo7!yZ|J=P+=^34DvbC$@jQGzQF#n82<^$S4{YhV8(7{&@fWTKcS|Ht5sD7G~Itg?kj4BQ$Dtnk6UPx3t z1g$F$BPEa?!xu6Gyqy`rPtz<+WrQ?gcCvdp*{^Noxm>R^<6JwTXTI%h`naXtV<*@Z zA}^-A*VZIL?RIH*a}+ExL@^^E73={SWY)bKu)3Y^Vtvnl{@tZA9Y!}fZgPksL8sdWhtt%V5}-+4cd^!s_vJ(gJf z9&mPIalbdNKh1HyH0`)<^6MY>{7?=f3_P!QnS)B|zK8X^t?x;$QAHrWBs+fJA(VH& z8ZC}5(W|%zHbjgTy4(iIr!O=jh9^gEde4Rq)H8@r|KilwgI^khVsQ5eR$#XW17a$X zfv)Pr^T&J2PT1lL$KOs=K2&amyy{2rbR6*;8F%~v+^?NJ-h-|)-+k?;CtkoEqobz? zKK$C-uf3hn;i2P!nfciTu>%S1%ZMTPa$aIx;Fjw8N@>9@#jw>Nb|6Ho1Tfv zJ-YMBYmlG!oIq=KVtr0R?%gM^DYnv1Le~0xTwO52j_-0Z$P5Rdi}PM$9l`}8<#+Bt z#DorX^tcSPcqm{44IZIK@!0LeEswu;I`~BB@e`*v4pZ41J41&~Y(DgA<-rr1ACHF) zcJu@~LkD`FN3e+BW3+7IN9JDA@``{*W~i4DAQpI5aW$bf1*cXY3eu4d0r`!K! zFw*|rpeg%51Z3>LI%R*mB@TE)mb@Q`eXs;v3GunX-z~wJ&-+qoA64o&!h!XUo^I9E zNct(uYNn61Y)YwP=TQpIYtH3x<5Q3gH|D)|z!98E_5O+mO};NO`)^vl-t#Ef@aD

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zh4Rm$iF1XH6*^JqMM5tXI#cKsLa!8BDs+X=>x5PaT`#m+Xq`~~_lp?6P4IT1cM1I~ zp#h&A!&dV{MkY;lln%XQK{c5bT#$~2YbRdNYVchQuP0h z&=$0@ek&>JcL)ulj`d?mQO|!wLi!)1;0a-$VEZ+ssQM4^8#^*<2& zBcX3d{T$><_PdG{{gw!Ak@{POep%?tLQf0T`3e1Wo`lViZnYep4}s?jE+++EEx1K+ zRPdJt?-l&0;Ddsn6Z|v5X9f2O4lvI^el{ue;onUYPZL}wc%|U5;CjLBf_biD{|5vg f5d5Uz9>K>2pA`I_;12}Dt?_p=vcG`lh@SrmSn+z^ literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.c new file mode 100755 index 00000000..8e497744 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.c @@ -0,0 +1,78 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include "g2_physical_device.h" +#include "g2_funix.h" +#include "g2_util.h" + + +g2_physical_device *g2_create_physical_device(int pid, + void *pdp, + g2_coor ct, + const g2_funix_fun *ff, + double a11, double a22, + double b1, double b2) +{ + g2_physical_device *rd; + int i, j; + + rd=g2_malloc(sizeof(g2_physical_device)); + + rd->pid=pid; /* physical device id (handled by driver) */ + rd->pdp=pdp; /* pointer to something */ + rd->coor_type=ct; /* coord. type */ + rd->a11=a11; /* device->physical device transformation */ + rd->a22=a22; + rd->b1=b1; + rd->b2=b2; + + rd->x_origin=0.0; /* User coordinates specification */ + rd->y_origin=0.0; + rd->x_mul=1.0; + rd->y_mul=1.0; + + rd->ff=g2_malloc(G2_N_FUNIX*sizeof(g2_funix_fun)); + + for(i=0;iff[i].fx=i; + rd->ff[i].fun=NULL; + for(j=0;ff[j].fx!=g2_FUNIX_NULL;j++) + if(ff[j].fx==i) { + rd->ff[i].fun = ff[j].fun; + break; + } + } + + return rd; +} + + +/* + * + * Destroy physical device + * + */ +void g2_destroy_physical_device(g2_physical_device *pd) +{ + g2_free(pd->ff); + g2_free(pd); +} + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.h new file mode 100755 index 00000000..d25d58ea --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.h @@ -0,0 +1,61 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_PHYSICAL_DEVICE_H +#define _G2_PHYSICAL_DEVICE_H + +#include "g2.h" +#include "g2_funix.h" + + +typedef enum _g2_coor { /* coord. type */ + g2_IntCoor, g2_DoubleCoor +} g2_coor; + + +typedef struct _g2_funix_fun { /* funix--function paar */ + g2_funix fx; /* function index */ + int (*fun)(); /* pointer to function */ +} g2_funix_fun; + + +typedef struct _g2_physical_device { + int pid; /* physical device id */ + void *pdp; /* pointer to something in phys. dev. */ + g2_coor coor_type; /* coordinate type */ + g2_funix_fun *ff; /* list of funix-function pairs */ + double a11, a22; /* coordinate transformation (ud->pd) */ + double b1, b2; /* Ar + B */ + + double x_origin; /* User coordinates specification */ + double y_origin; + double x_mul; + double y_mul; +} g2_physical_device; + + + +g2_physical_device *g2_create_physical_device(int pid, + void *pdp, + g2_coor ct, + const g2_funix_fun *ff, + double a11, double a22, + double b1, double b2); +void g2_destroy_physical_device(g2_physical_device *pd); + +#endif /* _G2_PHYSICAL_DEVICE_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_physical_device.o new file mode 100755 index 0000000000000000000000000000000000000000..a4cc2a04fb3681241548f61badde2d95969e0607 GIT binary patch literal 6056 zcma)A32YqI8GbW6Yme>qtnGCiCvotG9GE0t+aZ8)LWtvAxWU9YPD#VC$Jo2gddBR| znm9#JYA6^(K$JoYMW_N5fq+sdQbDv_r4-SFqXJQ3(L=33si3HbQbFr}|C@j8bpW+b zn)&|w{r~^oo0;9KdIozHMG^i`L_jQYLYy!>&2|Y*qE1A7Q;8$9e;VCCJoA^(T%qLk3Mf!&G$rSOXqq*^Je{gPt$ClHrG=%Z${^PT4(#9Z+iQK z`O(&Sv;FP&=0|tWoBarL!Vfds7n*&c?d6-M#7$41Mib74UTJ%_?e*F2SG2j3<7Ky; z^K*CAo;mH!nG*|zzje<1>y#_!XMP%*J#p|7^Uw=(-EV4SDdjI7|1-iMUu3Jz9n$Bz zLbKWine6N#{o;d%-lx2kYNe{A2KS9dq#|IfLHX(i5ilw$c2x)w0I7SVRtITE#g2*r zG$a@n6_O|+LWt6cqD07v41~}tJ=@?wq`h2-GT&8*a@N3^G!>F(JvmmbV8`luG^r*A?!1tf-)W(NNVQUFlZ>(OIFj%FmW)P~?@&ZqW0nCs@yHlfFRORm^VHj}f~@ zNn-+aeXHI`q1Gz4WVh>dSc8pRQM-OVrLmsbo%-Drd82X|KI;12dN&!Lu5?PaTTf8r z&B_Im?bTZ-@)pIFk^A&U@@-MBk!-&{NxtpMlr$dH??8oz?>D&vp13nPfTV*D0b)wmk^ zfUz19&A5XmG`K&q*$jk_Qg#&2*_gw_L48*)&W{sgx==ybI)Ja$B= zQECP@e|W553w7PglG8*L5!B*pG?9F?#}HUO^>&b@H-h{KF^1HQ;mJ%&sGIl%g(p*! 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Ralston and Wilf, Mathematical Methods for Digital Computers, + * Vol. II, John Wiley and Sons, New York 1967, pp. 156-158. + * 2. Greville, T.N.E., Ed., Proceedings of An Advanced Seminar + * Conducted by the Mathematics Research Center, U.S. Army, + * University of Wisconsin, Madison. October 7-9, 1968. Theory + * and Applications of Spline Functions, Academic Press, + * New York / London 1969, pp. 156-167. + * + * AUTHORS: + * + * Josef Heinen 04/06/88 + * Tijs Michels 06/16/99 + */ + +{ + int i, j; + double *x, *y, *g, *h; + double k, u, delta_g; + + if (n < 3) { + fputs("\nERROR calling function \"g2_c_spline\":\n" + "number of data points input should be at least three\n", stderr); + return; + } + if ((m-1)%(n-1)) { + fputs("\nWARNING from function \"g2_c_spline\":\n" + "number of curve points output for every data point input " + "is not an integer\n", stderr); + } + + x = (double *) g2_malloc(n*4*sizeof(double)); + y = x + n; + g = y + n; + h = g + n; /* for the constant copy of g */ + g2_split(n, points, x, y); + + n--; /* last value index */ + k = x[0]; /* look up once */ + u = (x[n] - k) / (m - 1); /* calculate step outside loop */ + for (j = 0; j < m; j++) sxy[j+j] = j * u + k; /* x-coordinates */ + + for (i = 1; i < n; i++) { + g[i] = 2. * ((y[i+1] - y[i]) / (x[i+1] - x[i]) - + (y[i] - y[i-1]) / (x[i] - x[i-1])) + / (x[i+1] - x[i-1]); /* whereas g[i] will later be changed repeatedly */ + h[i] = 1.5 * g[i]; /* copy h[i] of g[i] will remain constant */ + } + + k = 0.; + + do { + for (u = 0., i = 1; i < n; i++) { + delta_g = .5 * (x[i] - x[i-1]) / (x[i+1] - x[i-1]); + delta_g = (h[i] - + g[i] - + g[i-1] * delta_g - /* 8. - 4 * sqrt(3.) */ + g[i+1] * (.5 - delta_g)) * 1.0717967697244907832; + g[i] += delta_g; + + if (fabs(delta_g) > u) u = fabs(delta_g); + } /* On loop termination u holds the largest delta_g. */ + + if (k == 0.) k = u * eps; + /* Only executed once, at the end of pass one. So k preserves + * the largest delta_g of pass one, multiplied by eps. + */ + } while (u > k); + + m += m, i = 1, j = 0; + do { + u = sxy[j++]; /* x-coordinate */ + + while (x[i] < u) i++; + + if (--i > n) i = n; + + k = (u - x[i]) / (x[i+1] - x[i]); /* calculate outside loop */ + sxy[j++] = y[i] + + (y[i+1] - y[i]) * k + + (u - x[i]) * (u - x[i+1]) * + ((2. - k) * g[i] + + (1. + k) * g[i+1]) / 6.; /* y-coordinate */ + } while (j < m); + g2_free(x); +} + +void g2_spline(int id, int n, double *points, int o) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * o number of interpolated points per data point + * + * Given an array of n data points {x[1], y[1], ... x[n], y[n]} plot a + * spline curve on device id with o interpolated points per data point. + * So the larger o, the more fluent the curve. + */ + +{ + int m; + double *sxy; + + m = (n-1)*o+1; + sxy = (double*)g2_malloc(m*2*sizeof(double)); + + g2_c_spline(n, points, m, sxy); + g2_poly_line(id, m, sxy); + + g2_free(sxy); +} + +void g2_filled_spline(int id, int n, double *points, int o) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * o number of interpolated points per data point + */ + +{ + int m; + double *sxy; + + m = (n-1)*o+1; + sxy = (double*)g2_malloc((m+1)*2*sizeof(double)); + + g2_c_spline(n, points, m, sxy); + sxy[m+m] = points[n+n-2]; + sxy[m+m+1] = points[1]; + g2_filled_polygon(id, m+1, sxy); + g2_free(sxy); +} + +void g2_c_b_spline(int n, const double *points, int m, double *sxy) + +/* + * g2_c_b_spline takes n input points. It uses parameter t + * to compute sx(t) and sy(t) respectively + */ + +{ + int i, j; + double *x, *y; + double t, bl1, bl2, bl3, bl4; + double interval, xi_3, yi_3, xi, yi; + + if (n < 3) { + fputs("\nERROR calling function \"g2_c_b_spline\":\n" + "number of data points input should be at least three\n", stderr); + return; + } + x = (double *) g2_malloc(n*2*sizeof(double)); + y = x + n; + g2_split(n, points, x, y); + + m--; /* last value index */ + n--; /* last value index */ + interval = (double)n / m; + + for (m += m, i = 2, j = 0; i <= n+1; i++) { + if (i == 2) { + xi_3 = 2 * x[0] - x[1]; + yi_3 = 2 * y[0] - y[1]; + } else { + xi_3 = x[i-3]; + yi_3 = y[i-3]; + } + if (i == n+1) { + xi = 2 * x[n] - x[n-1]; + yi = 2 * y[n] - y[n-1]; + } else { + xi = x[i]; + yi = y[i]; + } + + t = fmod(j * interval, 1.); + + while (t < 1. && j < m) { + bl1 = (1. - t); + bl2 = t * t; /* t^2 */ + bl4 = t * bl2; /* t^3 */ + bl3 = bl4 - bl2; + + bl1 = bl1 * bl1 * bl1; + bl2 = 3. * (bl3 - bl2) + 4.; + bl3 = 3. * ( t - bl3) + 1.; + + sxy[j++] = (bl1 * xi_3 + bl2 * x[i-2] + bl3 * x[i-1] + bl4 * xi) / 6.; /* x-coordinate */ + sxy[j++] = (bl1 * yi_3 + bl2 * y[i-2] + bl3 * y[i-1] + bl4 * yi) / 6.; /* y-coordinate */ + + t += interval; + } + } + sxy[m] = x[n]; + sxy[m+1] = y[n]; + g2_free(x); +} + +void g2_b_spline(int id, int n, double *points, int o) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * o number of interpolated points per data point + */ + +{ + int m; + double *sxy; + + m = (n-1)*o+1; + sxy = (double*)g2_malloc(m*2*sizeof(double)); + + g2_c_b_spline(n, points, m, sxy); + g2_poly_line(id, m, sxy); + + g2_free(sxy); +} + +void g2_filled_b_spline(int id, int n, double *points, int o) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * o number of interpolated points per data point + */ + +{ + int m; + double *sxy; + + m = (n-1)*o+1; + sxy = (double*)g2_malloc((m+1)*2*sizeof(double)); + + g2_c_b_spline(n, points, m, sxy); + sxy[m+m] = points[n+n-2]; + sxy[m+m+1] = points[1]; + g2_filled_polygon(id, m+1, sxy); + + g2_free(sxy); +} + +/* + * FUNCTION g2_c_raspln + * + * FUNCTIONAL DESCRIPTION: + * + * This function draws a piecewise cubic polynomial through + * the specified data points. The (n-1) cubic polynomials are + * basically parametric cubic Hermite polynomials through the + * n specified data points with tangent values at the data + * points determined by a weighted average of the slopes of + * the secant lines. A tension parameter "tn" is provided to + * adjust the length of the tangent vector at the data points. + * This allows the "roundness" of the curve to be adjusted. + * For further information and references on this technique see: + * + * D. Kochanek and R. Bartels, Interpolating Splines With Local + * Tension, Continuity and Bias Control, Computer Graphics, + * 18(1984)3. + * + * AUTHORS: + * + * Dennis Mikkelson distributed in GPLOT Jan 7, 1988 F77 + * Tijs Michels t.michels@vimec.nl Jun 7, 1999 C + * + * FORMAL ARGUMENTS: + * + * n number of data points, n > 2 + * points double array holding the x and y-coords of the data points + * tn double parameter in [0.0, 2.0]. When tn = 0.0, + * the curve through the data points is very rounded. + * As tn increases the curve is gradually pulled tighter. + * When tn = 2.0, the curve is essentially a polyline + * through the given data points. + * sxy double array holding the coords of the spline curve + * + * IMPLICIT INPUTS: NONE + * IMPLICIT OUTPUTS: NONE + * SIDE EFFECTS: NONE + */ + +#define nb 40 +/* + * Number of straight connecting lines of which each polynomial consists. + * So between one data point and the next, (nb-1) points are placed. + */ + +void g2_c_raspln(int n, const double *points, double tn, double *sxy) +{ + int i, j; + double *x, *y; + double bias, tnFactor, tangentL1, tangentL2; + double D1x, D1y, D2x, D2y, t1x, t1y, t2x, t2y; + double h1[nb+1]; /* Values of the Hermite basis functions */ + double h2[nb+1]; /* at nb+1 evenly spaced points in [0,1] */ + double h3[nb+1]; + double h4[nb+1]; + + x = (double *) g2_malloc(n*2*sizeof(double)); + y = x + n; + g2_split(n, points, x, y); + +/* + * First, store the values of the Hermite basis functions in a table h[ ] + * so no time is wasted recalculating them + */ + for (i = 0; i < nb+1; i++) { + double t, tt, ttt; + t = (double) i / nb; + tt = t * t; + ttt = t * tt; + h1[i] = 2. * ttt - 3. * tt + 1.; + h2[i] = -2. * ttt + 3. * tt; + h3[i] = ttt - 2. * tt + t; + h4[i] = ttt - tt; + } + +/* + * Set local tnFactor based on input parameter tn + */ + if (tn <= 0.) { + tnFactor = 2.; + fputs("g2_c_raspln: Using Tension Factor 0.0: very rounded", stderr); + } + else if (tn >= 2.) { + tnFactor = 0.; + fputs("g2_c_raspln: Using Tension Factor 2.0: not rounded at all", stderr); + } + else tnFactor = 2. - tn; + + D1x = D1y = 0.; /* first point has no preceding point */ + for (j = 0; j < n - 2; j++) { + t1x = x[j+1] - x[j]; + t1y = y[j+1] - y[j]; + t2x = x[j+2] - x[j+1]; + t2y = y[j+2] - y[j+1]; + tangentL1 = t1x * t1x + t1y * t1y; + tangentL2 = t2x * t2x + t2y * t2y; + if (tangentL1 + tangentL2 == 0) bias = .5; + else bias = tangentL2 / (tangentL1 + tangentL2); + D2x = tnFactor * (bias * t1x + (1 - bias) * t2x); + D2y = tnFactor * (bias * t1y + (1 - bias) * t2y); + for (i = 0; i < nb; i++) { + sxy[2 * nb * j + i + i] = + h1[i] * x[j] + h2[i] * x[j+1] + h3[i] * D1x + h4[i] * D2x; + sxy[2 * nb * j + i + i + 1] = + h1[i] * y[j] + h2[i] * y[j+1] + h3[i] * D1y + h4[i] * D2y; + } + D1x = D2x; /* store as preceding point in */ + D1y = D2y; /* the next pass */ + } + +/* + * Do the last subinterval as a special case since no point follows the + * last point + */ + for (i = 0; i < nb+1; i++) { + sxy[2 * nb * (n-2) + i + i] = + h1[i] * x[n-2] + h2[i] * x[n-1] + h3[i] * D1x; + sxy[2 * nb * (n-2) + i + i + 1] = + h1[i] * y[n-2] + h2[i] * y[n-1] + h3[i] * D1y; + } + g2_free(x); +} + +void g2_raspln(int id, int n, double *points, double tn) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * tn tension factor [0.0, 2.0] + * 0.0 very rounded + * 2.0 not rounded at all + */ + +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+1; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_raspln(n, points, tn, sxy); + g2_poly_line(id, m, sxy); + + g2_free(sxy); +} + +void g2_filled_raspln(int id, int n, double *points, double tn) + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + * tn tension factor [0.0, 2.0] + * 0.0 very rounded + * 2.0 not rounded at all + */ + +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+2; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_raspln(n, points, tn, sxy); + sxy[(n+n-2) * nb + 2] = points[n+n-2]; + sxy[(n+n-2) * nb + 3] = points[1]; + g2_filled_polygon(id, m, sxy); + + g2_free(sxy); +} + +/* ---- And now for a rather different approach ---- */ + +/* + * FUNCTION g2_c_newton + * + * FUNCTIONAL DESCRIPTION: + * + * Use Newton's Divided Differences to calculate an interpolation + * polynomial through the specified data points. + * This function is called by + * g2_c_para_3 and + * g2_c_para_5. + * + * Dennis Mikkelson distributed in GPLOT Jan 5, 1988 F77 + * Tijs Michels t.michels@vimec.nl Jun 16, 1999 C + * + * FORMAL ARGUMENTS: + * + * n number of entries in c1 and c2, 4 <= n <= MaxPts + * for para_3 (degree 3) n = 4 + * for para_5 (degree 5) n = 6 + * for para_i (degree i) n = (i + 1) + * c1 double array holding at most MaxPts values giving the + * first coords of the points to be interpolated + * c2 double array holding at most MaxPts values giving the + * second coords of the points to be interpolated + * o number of points at which the interpolation + * polynomial is to be evaluated + * xv double array holding o points at which to + * evaluate the interpolation polynomial + * yv double array holding upon return the values of the + * interpolation polynomial at the corresponding points in xv + * + * yv is the OUTPUT + * + * IMPLICIT INPUTS: NONE + * IMPLICIT OUTPUTS: NONE + * SIDE EFFECTS: NONE + */ + +#define MaxPts 21 +#define xstr(s) __str(s) +#define __str(s) #s + +/* + * Maximum number of data points allowed + * 21 would correspond to a polynomial of degree 20 + */ + +void g2_c_newton(int n, const double *c1, const double *c2, + int o, const double *xv, double *yv) +{ + int i, j; + double p, s; + double ddt[MaxPts][MaxPts]; /* Divided Difference Table */ + + if (n < 4) { + fputs("g2_c_newton: Error! Less than 4 points passed " + "to function g2_c_newton\n", stderr); + return; + } + + if (n > MaxPts) { + fputs("g2_c_newton: Error! More than " xstr(MaxPts) " points passed " + "to function g2_c_newton\n", stderr); + return; + } + +/* First, build the divided difference table */ + + for (i = 0; i < n; i++) ddt[i][0] = c2[i]; + for (j = 1; j < n; j++) { + for (i = 0; i < n - j; i++) + ddt[i][j] = (ddt[i+1][j-1] - ddt[i][j-1]) / (c1[i+j] - c1[i]); + } + +/* Next, evaluate the polynomial at the specified points */ + + for (i = 0; i < o; i++) { + for (p = 1., s = ddt[0][0], j = 1; j < n; j++) { + p *= xv[i] - c1[j-1]; + s += p * ddt[0][j]; + } + yv[i] = s; + } +} + +/* + * FUNCTION: g2_c_para_3 + * + * FUNCTIONAL DESCRIPTION: + * + * This function draws a piecewise parametric interpolation + * polynomial of degree 3 through the specified data points. + * The effect is similar to that obtained using DISSPLA to + * draw a curve after a call to the DISSPLA routine PARA3. + * The curve is parameterized using an approximation to the + * curve's arc length. The basic interpolation is done + * using function g2_c_newton. + * + * Dennis Mikkelson distributed in GPLOT Jan 7, 1988 F77 + * Tijs Michels t.michels@vimec.nl Jun 17, 1999 C + * + * FORMAL ARGUMENTS: + * + * n number of data points through which to draw the curve + * points double array containing the x and y-coords of the data points + * + * IMPLICIT INPUTS: NONE + * IMPLICIT OUTPUTS: NONE + * SIDE EFFECTS: NONE + */ + +/* + * #undef nb + * #define nb 40 + * Number of straight connecting lines of which each polynomial consists. + * So between one data point and the next, (nb-1) points are placed. + */ + +void g2_c_para_3(int n, const double *points, double *sxy) +{ +#define dgr (3+1) +#define nb2 (nb*2) + int i, j; + double x1t, y1t; + double o, step; + double X[nb2]; /* x-coords of the current curve piece */ + double Y[nb2]; /* y-coords of the current curve piece */ + double t[dgr]; /* data point parameter values */ + double Xpts[dgr]; /* x-coords data point subsection */ + double Ypts[dgr]; /* y-coords data point subsection */ + double s[nb2]; /* parameter values at which to interpolate */ + + /* Do first TWO subintervals first */ + + g2_split(dgr, points, Xpts, Ypts); + + t[0] = 0.; + for (i = 1; i < dgr; i++) { + x1t = Xpts[i] - Xpts[i-1]; + y1t = Ypts[i] - Ypts[i-1]; + t[i] = t[i-1] + sqrt(x1t * x1t + y1t * y1t); + } + + step = t[2] / nb2; + for (i = 0; i < nb2; i++) s[i] = i * step; + + g2_c_newton(dgr, t, Xpts, nb2, s, X); + g2_c_newton(dgr, t, Ypts, nb2, s, Y); + for (i = 0; i < nb2; i++) { + sxy[i+i] = X[i]; + sxy[i+i+1] = Y[i]; + } + + /* Next, do later central subintervals */ + + for (j = 1; j < n - dgr + 1; j++) { + g2_split(dgr, points + j + j, Xpts, Ypts); + + for (i = 1; i < dgr; i++) { + x1t = Xpts[i] - Xpts[i-1]; + y1t = Ypts[i] - Ypts[i-1]; + t[i] = t[i-1] + sqrt(x1t * x1t + y1t * y1t); + } + + o = t[1]; /* look up once */ + step = (t[2] - o) / nb; + for (i = 0; i < nb; i++) s[i] = i * step + o; + + g2_c_newton(dgr, t, Xpts, nb, s, X); + g2_c_newton(dgr, t, Ypts, nb, s, Y); + + for (i = 0; i < nb; i++) { + sxy[(j + 1) * nb2 + i + i] = X[i]; + sxy[(j + 1) * nb2 + i + i + 1] = Y[i]; + } + } + + /* Now do last subinterval */ + + o = t[2]; + step = (t[3] - o) / nb; + for (i = 0; i < nb; i++) s[i] = i * step + o; + + g2_c_newton(dgr, t, Xpts, nb, s, X); + g2_c_newton(dgr, t, Ypts, nb, s, Y); + + for (i = 0; i < nb; i++) { + sxy[(n - dgr + 2) * nb2 + i + i] = X[i]; + sxy[(n - dgr + 2) * nb2 + i + i + 1] = Y[i]; + } + sxy[(n - 1) * nb2] = points[n+n-2]; + sxy[(n - 1) * nb2 + 1] = points[n+n-1]; +} + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + */ + +void g2_para_3(int id, int n, double *points) +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+1; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_para_3(n, points, sxy); + g2_poly_line(id, m, sxy); + + g2_free(sxy); +} + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + */ + +void g2_filled_para_3(int id, int n, double *points) +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+2; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_para_3(n, points, sxy); + sxy[m+m-2] = points[n+n-2]; + sxy[m+m-1] = points[1]; + g2_filled_polygon(id, m, sxy); + + g2_free(sxy); +} + +/* + * FUNCTION: g2_c_para_5 + * + * As g2_c_para_3, but now plot a polynomial of degree 5 + */ + +/* + * #undef nb + * #define nb 40 + * Number of straight connecting lines of which each polynomial consists. + * So between one data point and the next, (nb-1) points are placed. + */ + +void g2_c_para_5(int n, const double *points, double *sxy) +{ +#undef dgr +#define dgr (5+1) +#define nb3 (nb*3) + int i, j; + double x1t, y1t; + double o, step; + double X[nb3]; /* x-coords of the current curve piece */ + double Y[nb3]; /* y-coords of the current curve piece */ + double t[dgr]; /* data point parameter values */ + double Xpts[dgr]; /* x-coords data point subsection */ + double Ypts[dgr]; /* y-coords data point subsection */ + double s[nb3]; /* parameter values at which to interpolate */ + + /* Do first THREE subintervals first */ + + g2_split(dgr, points, Xpts, Ypts); + + t[0] = 0.; + for (i = 1; i < dgr; i++) { + x1t = Xpts[i] - Xpts[i-1]; + y1t = Ypts[i] - Ypts[i-1]; + t[i] = t[i-1] + sqrt(x1t * x1t + y1t * y1t); + } + + step = t[3] / nb3; + for (i = 0; i < nb3; i++) s[i] = i * step; + + g2_c_newton(dgr, t, Xpts, nb3, s, X); + g2_c_newton(dgr, t, Ypts, nb3, s, Y); + for (i = 0; i < nb3; i++) { + sxy[i+i] = X[i]; + sxy[i+i+1] = Y[i]; + } + + /* Next, do later central subintervals */ + + for (j = 1; j < n - dgr + 1; j++) { + g2_split(dgr, points + j + j, Xpts, Ypts); + + for (i = 1; i < dgr; i++) { + x1t = Xpts[i] - Xpts[i-1]; + y1t = Ypts[i] - Ypts[i-1]; + t[i] = t[i-1] + sqrt(x1t * x1t + y1t * y1t); + } + + o = t[2]; /* look up once */ + step = (t[3] - o) / nb; + for (i = 0; i < nb; i++) s[i] = i * step + o; + + g2_c_newton(dgr, t, Xpts, nb, s, X); + g2_c_newton(dgr, t, Ypts, nb, s, Y); + + for (i = 0; i < nb; i++) { + sxy[(j + 2) * nb2 + i + i] = X[i]; + sxy[(j + 2) * nb2 + i + i + 1] = Y[i]; + } + } + + /* Now do last TWO subinterval */ + + o = t[3]; + step = (t[5] - o) / nb2; + for (i = 0; i < nb2; i++) s[i] = i * step + o; + + g2_c_newton(dgr, t, Xpts, nb2, s, X); + g2_c_newton(dgr, t, Ypts, nb2, s, Y); + + for (i = 0; i < nb2; i++) { + sxy[(n - dgr + 3) * nb2 + i + i] = X[i]; + sxy[(n - dgr + 3) * nb2 + i + i + 1] = Y[i]; + } + sxy[(n - 1) * nb2] = points[n+n-2]; + sxy[(n - 1) * nb2 + 1] = points[n+n-1]; +} + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + */ + +void g2_para_5(int id, int n, double *points) +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+1; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_para_5(n, points, sxy); + g2_poly_line(id, m, sxy); + + g2_free(sxy); +} + +/* + * FORMAL ARGUMENTS: + * + * id device id + * n number of data points + * points data points (x[i],y[i]) + */ + +void g2_filled_para_5(int id, int n, double *points) +{ + int m; + double *sxy; /* coords of the entire spline curve */ + m = (n-1)*nb+2; + sxy = (double *) g2_malloc(m*2*sizeof(double)); + + g2_c_para_5(n, points, sxy); + sxy[m+m-2] = points[n+n-2]; + sxy[m+m-1] = points[1]; + g2_filled_polygon(id, m, sxy); + + g2_free(sxy); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_splines.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_splines.o new file mode 100755 index 0000000000000000000000000000000000000000..67bdd5037e5d68b14c08473f536f793a8201d104 GIT binary patch literal 17800 zcmch83w%`7wf8x5CeD$BWPqq3F^n4IVMquMAv}~vhKJ=Lj|9CW#z|%%(J&L|!NU>= z4H3q1fb`RQu?DKW-mh5Ot8HzK+Fp_n6T+inea%2l2#UWuNa`2RYa^oh{%h}jW+u^U z@7MeL4xCwgt-W4*?X}n5=gefgb;$x*mL>g?B}Iy1lJwkE-ZO=PvC@sw4LU1>`8ndug)+AmbUnlG6GO-?T)Mg_ZjOu zIqiX>mYGY>Yl>$4GIXxfuhSxNj!N2um zEu@8Bqp;*&sk$$mK#W2Rb^_LpKv77`drQ@fr!?bR;btxGlp1aieSrJJ@bM1&sowDM z&P(9v?fAH}JAAD3Qs;$GBPglwh1#{Wx98vw7)J% zU3dAH9`zTU(5y#aEjW4b{?}7)yA&f`G-+p`pz2=D_#Va=u)>wMdo|W*9-yf6L=6m|KJ z&ee=Z0@fBdc+mux=fPR%IS2LOgPT6NJNL>qgZ~OT!i|V6jU*4wAA@M<91ZGN=wi4j ze6sU==he<*6zkBr(DBYDEkT7vig>66QBQggA2hxr;r7mB82hJSNjp9l6Poh4k9n(w z;DsMq*s_EY^a5p7n=ymN^(=k7_Aow>O{zaHBdLMr9}Oc*z6+IKFMqPs zUuAqtGK?g|c!hdB|7*I(`m3%6s*;fZeqV3Em+CM2ELhx^@?xjo+7qyv=VNX7Lrq=A zXr{xezt!LCPeVp`M;hR#-wUq_k>}Q)D3?zS6nz$e#;U9SZa$iQSZ`zxM5~Gw$_%G+ zGq4In!38kf=C?-tN9Hr5$oZ&7vfJkGfnE7?SeDO3X2CX=l$O`iqotkI=BQfXS=GNa zLk(CXHH`*}PrOT2-*l<}deiGcVNI`rO2FIOvoQnj=uu^Xzn=$Q?LPxGErqPA1gz)d zL)8Y{f7(AQ<8>4aDLADKkupZ|zr@roJ)hIww-lb9KVv;V$8UXED+-;lsvT8GTNUFu1)aFD|%I+h*>iqVpm08S4l6T$RLfnAQx|50ad1DybhPN^D zK$V$qleP7r2A-rokb|kG0*uf9WTHDy?|;RK%dD&JXZ9tW+%p=t;A(Kwjz;ZJft_y4XMc+MFd zKo0Cgt0rQo>6NqtyV3RspP|p%3Vf#QS&LN~I6$M#`8*J$XlV0QZLX@x;b#0h(eaQu ze1dlCj$5_4=5RBX=AX0!mEdCw^O$yEGuol^*m9b*T1I~(^e1HMQS6vls5mL`tudwc zS(r+B>}e_sv}-1$A|&BR&Ywf)!cCpWJ5Fk~qzaaTObu;J$0&*&K^k26L}wFkT{MgM zb2rD= z2{2(NY=akxCA9@vCW4Yg+H&5v@6*1{g7y1ywshN>ld! z7E>PxQflS=IcW4F_Xh6w2dGm-Julp&<%N3#L7Iz>$N4bY(Vz^X*wPSy(s+Q@w@EZG zA@yzid##{^UeU>l;`stp{Vsm9*Lmcfn|S|V)6=)82Hj8c~68Frf~n676rQM9`! zHB9CWzT5Dmqg{9gO+6#{YhSzjf7)?rxkgYkHMHzM8UU0^(iM zdtJ)j%Lr}GncO2)8Nu4&m;3q#8vUleC>D&Cr9@kcsnhO{3cJ%aaWt;G|rCk}T9TUH1du`}1-yZ*9&wGqWfu zCHN$?Ys~sL&bR#h-k5ti+*~yQ^Qsv`!QX>jpMTUz`}@6}v}#E=wBqR6yfuPy5e`^W zwY1QDnAqAtQAaL4w2>C@H`f*EkkYvgG6J?_8zzxe3G=1$H7|i1Pg+@j$lQ8M*OwJ9}Gq~ zo7zB92xU^7WNVkehY{2x%gpw8A6mwh#CTwf5>?X``YT z)rqwLGyc}dUlQP zqe2S1crUpn;;Ypksm8Xi2N>vXpj6qv7_;q6AB%8J+dYV3AV|^94N{O(_WlBOo#zpa zxeJa&$IKt|zk9qi(!n|)u_%eTrSOSW6d6uslcfhT zE4A8x3Z+)BPqFc{y-y?<#;@;eG=47J^noc5q;!%`%Z*xIQ;+tOYWR;dMNT7OW zfqKf%dr10k*Sp~`4v|f~-i@WT6(ky~cbnO&BCWjMu|kMd#ayR)_ZxI!i==@C%Q&0b zKvFz6qmn`LnTsW5M7Dx+K)qvz^?FB|$fthwE(t~gwG_jeNP@psMFaKD%jz9PFjnuF zm#B9v(lKw1k(V!udN*)C|A#`Y)h=S=;i0BdkU?SN8}eZ^rT+CmL_Avmc=RX$1L|Ka zdNiVF^zK9`u`_`bH&eWTL?w8Z#m25iR7l0uKQe~}FX6aK)qny{>mO*W{!zsB`bX{D zAO$^T?@w6$qr9U0dH|3H%{=(F`X|P_T(9^2b1YiQ)Zmlk{;O=ajCpR1Ec;x~uGiT9 z%hHYI7oTCOdMqLFl*x5qRYitFil@uB);}@+YFLaL|8Agc{L88SQLeH2N9pyq>mRM} z|JnNYhyU;O@9uxF{z;NNL^fYD6rZD$hb1b>BaP>RaFft=a*Cj|fkh?xn&PQ6_Fa;QCA08)|FeYj7FbljKAsoUuCFw?Ci6JBV zv+E;BiwTg@o5TnpLTI`efj~z^V*rD?220EeiQJrsIU~1kiH-BFq*?TK<|#ZF;6Q}S zh<-`>nfO+QYOeeNJ}N*olsmnWF+nj-BED+sy2eo~ndnQ{TSL-6CGLcTXNj`!L85S_*JPvPL)=d&S*8}E zUn`FWFx)Dcegb92WI29WKzZCL5t61e$4*$WAae%IC&XE^Gx(5mT|mHUlkZ`U0}MF zoV;EBA=A9j^eXjc%K?TiGFiybbonvHyu`GWdhe7exQ1I-n^qHgmq70|)e`eu;YOh; 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With the + * g2_pen() function it is possible to choose a pen created by the + * g2_ink() function. Note that g2_ink function is only defined for + * physical devices. The predefined colors (see g2_test demo program) + * have pens from 0 till 26 (inclusive). + * + * Some basic colors are: + * - 0 white + * - 1 black + * - 3 blue + * - 7 green + * - 19 red + * - 25 yellow + * + */ + + +/** + * \ingroup interface + * \defgroup control output control + */ + +/** + * + * Flush output buffers. + * + * \param dev device id + * + * \ingroup control + */ +void g2_flush(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_flush: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_flush_pd(devp->d.pd); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_flush(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Save output + * + * \param dev device id + * + * \ingroup control + */ +void g2_save(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_save: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_save_pd(devp->d.pd); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_save(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Clear device + * + * \param dev device number + * + * \ingroup control + */ +void g2_clear(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_clear: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_clear_pd(devp->d.pd); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_clear(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + +/** + * + * Set pen color for all following operations, see also g2_ink(). + * + * \param dev device + * \param color pen (either one of default pens 0-26, or a pen returned by g2_ink() ) + * + * \ingroup color + */ +void g2_pen(int dev, int color) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_pen: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_pen_pd(devp->d.pd, color); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_pen(devp->d.vd->dix[i], color); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Set the background color + * + * \param dev device + * \param color pen (either one of default pens 0-26, or a pen returned by g2_ink() ) + * + * \ingroup color + */ +void g2_set_background(int dev, int color) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_set_background: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_set_background_pd(devp->d.pd, color); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_set_background(devp->d.vd->dix[i], color); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Create an ink. To put ink into the pen use g2_pen(). + * + * \param pd_dev physical device + * \param red red component (0-1) according to the RGB color model + * \param green green component (0-1) according to the RGB color model + * \param blue blue component (0-1) according to the RGB color model + * \return new pen, see g2_pen() + * + * \ingroup color + */ +int g2_ink(int pd_dev, double red, double green, double blue) +{ + g2_device *devp; + int rv=-1; + + if((devp=g2_get_device_pointer(pd_dev))==NULL) { + fprintf(stderr, "g2_ink: No such device: %d\n", pd_dev); + return -1; + } + + if(red < 0.0) red=0.0; + if(green < 0.0) green=0.0; + if(blue < 0.0) blue=0.0; + if(red > 1.0) red=1.0; + if(green > 1.0) green=1.0; + if(blue > 1.0) blue=1.0; + + switch(devp->t) { + case g2_PD: + rv=g2_ink_pd(devp->d.pd, red, green, blue); + break; + case g2_VD: + fprintf(stderr, "g2_ink: g2_ink is enabled only for phys. devices\n"); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=pd_dev; + return rv; +} + + + +/** + * + * Clear collor palette (remove all inks) and reallocate basic colors. + * + * \param dev device + * + * \ingroup color + */ +void g2_reset_palette(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_reset_palette: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_clear_palette(dev); + g2_allocate_basic_colors(dev); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_reset_palette(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Remove all inks. + * + * \param dev device + * + * \ingroup color + */ +void g2_clear_palette(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_clear_palette: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_clear_palette_pd(devp->d.pd); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_clear_palette(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + +/** + * + * Allocate basic colors + * + * \param dev device + * + * \ingroup color + */ +void g2_allocate_basic_colors(int dev) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_allocate_basic_colors: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_allocate_basic_colors_pd(devp->d.pd); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_allocate_basic_colors(devp->d.vd->dix[i]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + +/** + * + * Set font size + * + * \param dev device + * \param size new font size + * + * \ingroup control + */ +void g2_set_font_size(int dev, double size) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_set_font_size: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_set_font_size_pd(devp->d.pd, size); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_set_font_size(devp->d.vd->dix[i], size); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Set line width. + * + * \param dev device + * \param w new line width + * + * \ingroup control + */ +void g2_set_line_width(int dev, double w) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_set_line_width: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_set_line_width_pd(devp->d.pd, w); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_set_line_width(devp->d.vd->dix[i], w); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Set line dash. Set \a N to 0 and \a dashes to NULL to restore solid line. + * + * \param dev device + * \param N number of dash components (0 for solid line) + * \param dashes vector of dash lengths (black, white, black, ...) + * + * \ingroup control + */ +void g2_set_dash(int dev, int N, double *dashes) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_set_dash: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_set_dash_pd(devp->d.pd, N, dashes); + break; + + case g2_VD: + for(i=0;id.vd->N;i++) + g2_set_dash(devp->d.vd->dix[i], N, dashes); + break; + + case g2_ILLEGAL: + break; + + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Set QuasiPixel size and shape. + * + * \param dev device + * \param d size + * \param shape shape (rectangle or circle, see ::QPshape ) + * + * \ingroup control + */ +void g2_set_QP(int dev, double d, enum QPshape shape) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_set_QP: No such device: %d\n", dev); + return; + } + + devp->QPd=d; + devp->QPshape=shape; + + __g2_last_device=dev; +} + + +/** + * + * Query pointer (e.g. mouse for X11) position and button state. See + * the demo program pointer.c for an example. + * + * \param dev device + * \param x returns pointer x coordinate + * \param y returns pointer y coordinate + * \param button returns button state + * + * \ingroup control + */ +void g2_query_pointer(int dev, double *x, double *y, unsigned int *button) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_query_pointer: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_query_pointer_pd(devp->d.pd, x, y, button); + break; + case g2_VD: + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Get pointers to physical device specific handles. This function + * should be used only if you are familiar with the g2 source code. + * For details see physical device source code (e.g. in src/X11/). + * Example usage can be found in demo/handles.c. + * + * \param pd physical device + * \param handles returns pointers to physical device low level handles + * + * \ingroup control + */ +void g2_get_pd_handles(int pd, void *handles[G2_PD_HANDLES_SIZE]) +{ + g2_device *devp; + int i; + + for(i=0;it) { + case g2_PD: + g2_get_pd_handles_pd(devp->d.pd, handles); + break; + case g2_VD: + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_control.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_control.o new file mode 100755 index 0000000000000000000000000000000000000000..979b640a1d714f59c6b57c89e49bc01ca9fc48c0 GIT binary patch literal 15132 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a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_device.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_device.c new file mode 100755 index 00000000..418b4ed8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_device.c @@ -0,0 +1,196 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include + +#include "g2.h" +#include "g2_funix.h" +#include "g2_device.h" +#include "g2_util.h" + +/** + * \ingroup interface + * \defgroup device devices control + */ + + +/** + * + * Close and delete a device. + * + * \param dev device + * + * \ingroup device + */ +void g2_close(int dev) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_close: Warning! No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + devp->d.pd->ff[g2_Delete].fun(devp->d.pd->pid, + devp->d.pd->pdp); + break; + case g2_VD: + while(devp->d.vd->N>0) /* close all devices */ + g2_close(devp->d.vd->dix[devp->d.vd->N-1]); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + g2_destroy_device(dev); /* destroy device */ +} + + +/** + * + * Set auto flush mode for device \a dev. Auto flush mode means that after each graphical + * operation g2 library automatically calls flush function to ensure that output is realy + * displayed. However, freqent flushing decreases performance. Alternative is to flush + * output when needed by calling g2_flush function. + * + * \param dev device + * \param on_off 1-on 0-off + * + * \ingroup device + */ +void g2_set_auto_flush(int dev, int on_off) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + g2_log(Error, "g2: Error! g2_set_auto_flush: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + break; + case g2_VD: + for(i=0;id.vd->N;i++) { + g2_set_auto_flush(devp->d.vd->dix[i], on_off); + } + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + devp->auto_flush=on_off; /* set auto flush for all (vd and pd) devices */ + __g2_last_device=dev; +} + + +/** + * + * Set the user coordinate system. + * + * \param dev device + * \param x_origin x coordinate of the new origin (expressed in the default coordinate system) + * \param y_origin x coordinate of the new origin (expressed in the default coordinate system) + * \param x_mul x scaling factor + * \param y_mul y scaling factor + * + * \ingroup device + */ +void g2_set_coordinate_system(int dev, + double x_origin, double y_origin, + double x_mul, double y_mul) +{ + g2_device *devp; + int i; + + if(x_mul==0.0 || y_mul==0.0) { + fprintf(stderr, + "g2_set_coordinate_system: Error! Multiplicator can not be 0.0"); + return; + } + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, + "g2_set_coordinate_system: Warning! No such device: %d\n", + dev); + return; + } + + switch(devp->t) { + case g2_PD: + devp->d.pd->x_origin=x_origin; + devp->d.pd->y_origin=y_origin; + devp->d.pd->x_mul=x_mul; + devp->d.pd->y_mul=y_mul; + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_set_coordinate_system(devp->d.vd->dix[i], + x_origin, y_origin, + x_mul, y_mul); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Get the last accessed device. G2LD macro is defined as the g2_ld function. + * + * \code + * g2_open_X11(100, 100); + * g2_plot(G2LD, 50, 50); + * \endcode + * + * \ingroup device + */ +int g2_ld(void) +{ + return __g2_last_device; +} + + + +/** + * + * Set the last accessed device. See also g2_ld() function. + * + * \param dev device + * + * \ingroup device + */ +void g2_set_ld(int dev) +{ + if(!g2_device_exist(dev)) { + fprintf(stderr, "g2_set_lsd: Warning! No such device: %d\n", dev); + return; + } + __g2_last_device=dev; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_device.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_device.o new file mode 100755 index 0000000000000000000000000000000000000000..3091c62a105f633c31610cac22b8ca48c00cd10f GIT binary patch literal 8612 zcma)B4|G)3nZNJPWFE=nO(1~~2r?{z29QYtDTWjgNG6arjp0v#Q;Fjw^OB5CX2Q%H zOz=;(25o1v6tvpbp0?6Io_4$I)>f^$d#ap8MR#56>3RxwHC&ZpkLHiL{S#vRg66Irzo5Gd@;Ph#g|eG&?m0v9i4EpN>*0%e z(^H>lu_nsy{l(bnE40Aw3P3mCT4R!qfWf70fy=e>ZjJQ}1wvZimK}EM4R{Rkjh~yF zzw6?}T~@y5gM98neqBMBneiswoj(x?b#mq+veZR*=Tp`n#X{zvW{`&we?7XN~o2Err}sV;(naXtw3Nojq`H zpOEqHo{R)0BNcDHf^adhlRc*=Bh_!dGTC!#GExI>&j*t|C*ORJIImAeP9nR>GjE;x z)_&bBn~c2vE9&Rg>~B14=Fd-_l(TX?QbyS!x#N)ljffnNN31>6L#mMqWGfe^a1nzC z9wfP3$eU>)%k!TEj%2%s>;0E#wNH+dL#Z6fAJ=jujfc%IpMRFmunOa%V zEZmpacRr9uQ@XnDhvVcBdp zoH-ZS&8h^YVkn>16rv&w$qfN7@=pY2YO}NrFrV$4@}`5F(>RqIk(H2gszlC(l!qp= zDlDcQwwEiH^QL{=5Lg#LRIB}%OP~-Y?Naey9wBxBwKKS#08^)mH~spL4KOV|3()=g z9j0WK`@k&Hm%&{38HtoDOrL%cmX=Td3YeDPEP=|5LuvB#JJ^~&vzIuBcTW5EnO`E} zYcy<8Q7zyRxPQV;WYY56BrRhy;Qua>Gnp*& z{{viFvzV;#{}4W`awg~cbBM{RV6xhuCFyJ?L;f-vsFKMV|ML{pTqbM%bu>^Flh^t~ zB%QAff~zmC_t%r>1zJjyjsAB?x{xz!@~>B?!f19BkpoAO1@smT`fwV0R0EVXcqO@pM^7FJGg10^v}Uu z3ZZE(v?;zZ`&QhA{TYm}+3V2P?KS8db{u!pK15^KW4IUDKL7{21b54R5u6!zKU^2v zCvY#Ze+k=w{UM~K_B`Be`#&*O(7q4%GP?=)nf5if&$9m!n&tLmu&S^dz?p5If&Lu3 z9sElBL-6O?yD^1T_EPZY+123Fb4!S78;=sP!2T_Ct`Vk8G$C0HONe3p8Y%+ z!oD81nlQf#fl)nyd(jEpz6eXpSQzXd5k`n619cJX&!vR1=xs@vqKrB;_cJlOWMgiC zk@06gLbvEqcx{5L%UBW|PQ-<=l#44k93K|OC%g?}7B5BoMlD69FSdgH{lZvAruyPQ zFxJo@jOBkVsj^^f)v76KZm<`k6`m**?1hAh+Tv%SZ>;o0^~GZpQP`uJieD#Lokwjb zF2_93a2TEg^0&8&D$|GM#JwZli$GTm$)q7oM5N$RjNGVi4ozOOHzHY33K9` zZ@|J=^)oO_=fTrz3~%by_9Kvu*{?z7Fuzu>3A#dGLIct2P(V6Qvl)c#@+DGY1;OX}2?R%l zeyx{tMX^gktn?D94sPv&4bN4mn5sgrqk7R7*9!9%>eP3_VTC9{0y7bbM$cm*j^NU| zXUCm=LaQZb+Ri!iA<>pg&FzSrLax|Kc8|cV)}@gR)tj=rQQGaQybg+*B=q|Oo|mnj zm$?a{ZS%Z~ikHY$2Mu)xoC)zTqEoI$Jf%w72->Jj_5Q(1+6aoerII#+w%?QOuB45i zs4j2NJEsS|%L`3ZX>AnTkL1(q2nPJ29JE5m>88z~Sf0}!2a8TO70b`0?RGKmVGQX1 z5(0u5V9`*jy!9Bw2N_0r(5NLXp@OJv;KRZ5;X z>&6plbdgpv(W|=d=&+Lo7r9{1LWWYR)yCGHH0-CFdyUa+&XBK z?X?y`qdOiq+<$-ny=(5y;4(%I8cVGgQ57xMfAV_k8^*$?jo4aa;ogG#TJ%3>)fls$ zjvKib-`1Ddu-ktyzN5KW{u#NyGOE@Z1ARu-USnXbQ8h;QWlvwTW2I3#wzv83<5BB= zy$I7wbJUkiXPxHIu2?3ONDV9sb*4kvT;E{Go4e-Fk~rRc239qPBAHA&vnT|Utm8&w zIX4~cPv)|N%^z(-zDcn!ozBD)shI0Tv!hwp8JhC+*<8|13@5Q7ZaNd{i={%Tv>WPm zLiOQ#OyS4d|EXBzxXEn%Pi2MU2jk#H{E{ZLJFS3e(jiby>&NW~aHDPAt8XgxMaE4! zv8LoCd#pg-_64K;K6Bis?5RxKaVh)G`^^3?7~?+m*aFlnLfweW~WJbHvcu#dQBAOjcXWZUgzlgTq7)_@8Zi~7i3au;ZPr0~ihls6R zeF@Y&s?Ev3AH2X@)Je&)wmWV|BIWE##N9!1(UNpxnXXvUaa|czdq+oP^TrNoc6%m) zeMg45R5me?a^fL+msVCXDjHtY4W@^jy4#$L>ty%WZFW)#r*2asRkt(Yq*AeMog1fn zD;vUV>cHtwXB_P3Ox?h$mG$B4>IEuhSVV_n8Mw&`ISFz!N*%H&Jtk;q`M9Aw^2|7W zn4A7&Y#=Lx@v4rr+NicfbU2+A)3qi>qv=dyAd!;F(~gqq)IdnyuFSJ7kxV-A9hpQd zHIQ_?xs3JQmK%=t#M7F zepfP$m4L3dfC7gOR`#+(WqOur6OBfPa>?lgdZ`c#czgiY9{1DSLV#Va2o;_Ce!O()}1vxK7=Wr6(K+B+gNB7C&QsD`ri zEE<`r9H@BPgEqv7w~A1|dJ4Q0X!Y7PtaO;xkSN6 zTsLK8P{8E4^I!nAyYL%&gV z(5I%(!WHO~z7l_&9=*Sif7M8jzF<^ST{`DgpJazH5S{R=FX9*O=3datk!fzl)N-r_vrEmar;%sC)c9+Vg5 zTIer?`k?PG)s#O)D=g%j;&+!6pYZbkybxVD0?}$Wcvglem^f*#s#?iuMW>q~-?=_8 z%QKiyLiXoqDUShez_1oC4}BT6CVZZ!zR^H zA4?do1CrflqEQInB^vh6G5-zX!~T7uVc(1b(koHdK(eDBMM?iVgpfZ+a@5PqOrIcx z-YG)pohCWrqP?PH%XKr}!T2hThmXF8SdVtShEkw^AZU1K(7I`mAq9!_eW*c5|KuTD z#JH4kC1WGwrx-UewlnTxl+SkfahM)vyq)nL#zTy>=V;vTF#eeFDC5r=f6e$?#*2(4 zG_SCq$4I}W5#7W{>q7KSMu(Apvm^dE;{%M}W_+CSdB)cmCmGK%{*kd5b4vcI7*{Z^ zVO-DH!T34GM;O1)_!#3ej7J$?VtkeH7mOzv>1Tc#|2K^9GQQ7vo{|3BLwY(MpM(~p z%~-)Wk1@o!l<``|RgCmQJNa49*vj~6#xBO4jC&Y+83!3tj4tDT#?LbzX8aoCw-_H~ ze3J1D;|0cQ919fR5F`C3jOaY$R~i3?k^V74a{B)h;aSE%FzTo!;#-V1V+G@U#_fy` zGd{)m0^=Ku|4N88d5iJ)%nzV&X`FIG$SWCFFn=xMF2FD6@!v-8y_8Tr$Nm>!w?F3q literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_graphic.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_graphic.c new file mode 100755 index 00000000..f8e1c015 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_graphic.c @@ -0,0 +1,1045 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include + +#include "g2_device.h" +#include "g2_graphic_pd.h" +#include "g2_util.h" + +/** + * \ingroup interface + * \defgroup graphic graphical output + */ + +/** + * + * Move graphic cursor. + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * + * \ingroup graphic + */ +void g2_move(int dev, double x, double y) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_move: No such device: %d\n", dev); + return; + } + + devp->x=x; /* set graph. cursor */ + devp->y=y; + + switch(devp->t) { + case g2_PD: + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_move(devp->d.vd->dix[i], x, y); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Move graphic cursor relative to the currner graphical cursor position. + * + * \param dev device + * \param dx x coordinate increment + * \param dy y coordinate increment + * + * \ingroup graphic + */ +void g2_move_r(int dev, double dx, double dy) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_move_r: No such device: %d\n", dev); + return; + } + + devp->x+=dx; /* set graph. cursor */ + devp->y+=dy; + + switch(devp->t) { + case g2_PD: + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_move_r(devp->d.vd->dix[i], dx, dy); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + __g2_last_device=dev; +} + + + +/** + * + * Plot a point + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * + * \ingroup graphic + */ +void g2_plot(int dev, double x, double y) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_plot: No such device: %d\n", dev); + return; + } + + devp->x=x; /* set graph. cursor */ + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_plot_pd(devp->d.pd, x, y); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_plot(devp->d.vd->dix[i], x, y); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Plot a point relative to graphical cursor. + * + * \param dev device + * \param rx relative x coordinate + * \param ry relative y coordinate + * + * \ingroup graphic + */ +void g2_plot_r(int dev, double rx, double ry) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_plot_r: No such device: %d\n", dev); + return; + } + + g2_plot(dev, devp->x+rx, devp->y+ry); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a line from \p x1, \p y1 to \p x2, \p y2. + * + * \param dev device + * \param x1 see above + * \param y1 see above + * \param x2 see above + * \param y2 see above + * + * \ingroup graphic + */ +void g2_line(int dev, double x1, double y1, double x2, double y2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_line: No such device: %d\n", dev); + return; + } + + devp->x=x2; + devp->y=y2; + + switch(devp->t) { + case g2_PD: + g2_line_pd(devp->d.pd, x1, y1, x2, y2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_line(devp->d.vd->dix[i], x1, y1, x2, y2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw line relative to the graphic cursor. + * + * \param dev device + * \param dx relative x coordinate + * \param dy relative y coordinate + * + * \ingroup graphic + */ +void g2_line_r(int dev, double dx, double dy) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_line_r: No such device: %d\n", dev); + return; + } + g2_line(dev, devp->x, devp->y, devp->x+dx, devp->y+dy); + + __g2_last_device=dev; +} + + + +/** + * + * Draw line from graphic cursor to the point \a x, \a y + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * + * \ingroup graphic + */ +void g2_line_to(int dev, double x, double y) +{ + g2_device *devp; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_line_to: No such device: %d\n", dev); + return; + } + g2_line(dev, devp->x, devp->y, x, y); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a poly line. + * + * \param dev device + * \param N_pt number of points (Note: It is not size of \a points vector!) + * \param points vector of coordinates: x1, y1, x2, y2, ... + * + * \ingroup graphic + */ +void g2_poly_line(int dev, int N_pt, double *points) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_poly_line: No such device: %d\n", dev); + return; + } + + devp->x=points[2*(N_pt-1)+0]; + devp->y=points[2*(N_pt-1)+1]; + + switch(devp->t) { + case g2_PD: + g2_poly_line_pd(devp->d.pd, N_pt, points); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_poly_line(devp->d.vd->dix[i], N_pt, points); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a triangle described by 3 corner points. + * + * \param dev device + * \param x1 x coordinate of the 1st corner + * \param y1 y coordinate of the 1st corner + * \param x2 x coordinate of the 2nd corner + * \param y2 y coordinate of the 2nd corner + * \param x3 x coordinate of the 3rd corner + * \param y3 y coordinate of the 3rd corner + * + * \ingroup graphic + */ +void g2_triangle(int dev, + double x1, double y1, + double x2, double y2, + double x3, double y3) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_triangle: No such device: %d\n", dev); + return; + } + + devp->x=x3; + devp->y=y3; + + switch(devp->t) { + case g2_PD: + g2_triangle_pd(devp->d.pd, + x1, y1, + x2, y2, + x3, y3); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_triangle(devp->d.vd->dix[i], x1, y1, x2, y2, x3, y3); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled triangle specified by the 3 corner points. + * + * \param dev device + * \param x1 x coordinate of the 1st corner + * \param y1 y coordinate of the 1st corner + * \param x2 x coordinate of the 2nd corner + * \param y2 y coordinate of the 2nd corner + * \param x3 x coordinate of the 3rd corner + * \param y3 y coordinate of the 3rd corner + * + * \ingroup graphic + */ +void g2_filled_triangle(int dev, + double x1, double y1, + double x2, double y2, + double x3, double y3) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_triangle: No such device: %d\n", dev); + return; + } + + devp->x=x3; + devp->y=y3; + + switch(devp->t) { + case g2_PD: + g2_filled_triangle_pd(devp->d.pd, + x1, y1, + x2, y2, + x3, y3); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_triangle(devp->d.vd->dix[i], x1, y1, x2, y2, x3, y3); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a rectangle specified by the two opposite corner points. + * + * \param dev device + * \param x1 x coordinate of the 1st corner + * \param y1 y coordinate of the 1st corner + * \param x2 x coordinate of the 3rd corner + * \param y2 y coordinate of the 3rd corner + * + * \ingroup graphic + */ +void g2_rectangle(int dev, double x1, double y1, double x2, double y2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_rectangle: No such device: %d\n", dev); + return; + } + + devp->x=x2; + devp->y=y2; + + switch(devp->t) { + case g2_PD: + g2_rectangle_pd(devp->d.pd, x1, y1, x2, y2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_rectangle(devp->d.vd->dix[i], x1, y1, x2, y2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled rectangle specified by the two opposite corner points. + * + * \param dev device + * \param x1 x coordinate of the 1st corner + * \param y1 y coordinate of the 1st corner + * \param x2 x coordinate of the 3rd corner + * \param y2 y coordinate of the 3rd corner + * + * \ingroup graphic + */ +void g2_filled_rectangle(int dev, double x1, double y1, double x2, double y2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_rectangle: No such device: %d\n", dev); + return; + } + + devp->x=x2; + devp->y=y2; + + switch(devp->t) { + case g2_PD: + g2_filled_rectangle_pd(devp->d.pd, x1, y1, x2, y2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_rectangle(devp->d.vd->dix[i], x1, y1, x2, y2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a polygon. + * + * \param dev device + * \param N_pt number of points (Note: It is not size of \a points vector!) + * \param points vector of coordinates: x1, y1, x2, y2, ... + * + * \ingroup graphic + */ +void g2_polygon(int dev, int N_pt, double *points) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_polygon: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_polygon_pd(devp->d.pd, N_pt, points); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_polygon(devp->d.vd->dix[i], N_pt, points); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled polygon. + * + * \param dev device + * \param N_pt number of points (Note: It is not size of \a points vector!) + * \param points vector of coordinates: x1, y1, x2, y2, ... + * + * \ingroup graphic + */ +void g2_filled_polygon(int dev, int N_pt, double *points) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_polygon: No such device: %d\n", dev); + return; + } + + switch(devp->t) { + case g2_PD: + g2_filled_polygon_pd(devp->d.pd, N_pt, points); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_polygon(devp->d.vd->dix[i], N_pt, points); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw an ellipse. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r1 x radius + * \param r2 y radius + * + * \ingroup graphic + */ +void g2_ellipse(int dev, double x, double y, double r1, double r2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_ellipse: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_ellipse_pd(devp->d.pd, x, y, r1, r2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_ellipse(devp->d.vd->dix[i], x, y, r1, r2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled ellipse. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r1 x radius + * \param r2 y radius + * + * \ingroup graphic + */ +void g2_filled_ellipse(int dev, double x, double y, double r1, double r2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_ellipse: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_filled_ellipse_pd(devp->d.pd, x, y, r1, r2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_ellipse(devp->d.vd->dix[i], x, y, r1, r2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a circle. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r radius + * + * \ingroup graphic + */ +void g2_circle(int dev, double x, double y, double r) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_circle: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_circle_pd(devp->d.pd, x, y, r); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_circle(devp->d.vd->dix[i], x, y, r); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled circle. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r radius + * + * \ingroup graphic + */ +void g2_filled_circle(int dev, double x, double y, double r) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_circle: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_filled_circle_pd(devp->d.pd, x, y, r); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_circle(devp->d.vd->dix[i], x, y, r); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw an arc. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r1 x radius + * \param r2 y radius + * \param a1 starting angle (in deg. 0-360) + * \param a2 ending angle (in deg. 0-360) + * + * \ingroup graphic + */ +void g2_arc(int dev, + double x, double y, + double r1, double r2, + double a1, double a2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_arc: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_arc_pd(devp->d.pd, x, y, r1, r2, a1, a2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_arc(devp->d.vd->dix[i], x, y, r1, r2, a1, a2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a filled arc. + * + * \param dev device + * \param x x coordinate of the center + * \param y y coordinate of the center + * \param r1 x radius + * \param r2 y radius + * \param a1 starting angle (in deg. 0-360) + * \param a2 ending angle (in deg. 0-360) + * + * \ingroup graphic + */ +void g2_filled_arc(int dev, + double x, double y, + double r1, double r2, + double a1, double a2) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_filled_arc: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_filled_arc_pd(devp->d.pd, x, y, r1, r2, a1, a2); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_filled_arc(devp->d.vd->dix[i], x, y, r1, r2, a1, a2); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw string, see also g2_set_font_size(). + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * \param text null terminated string + * + * \ingroup graphic + */ +void g2_string(int dev, double x, double y, const char *text) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_string: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_string_pd(devp->d.pd, x, y, text); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_string(devp->d.vd->dix[i], x, y, text); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Draw a pen image + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * \param x_size x size + * \param y_size y size + * \param pens vector of x_size*y_size pens: p11, p21, ... pxy, ... + * + * \ingroup graphic + */ +void g2_image(int dev, double x, double y, int x_size, int y_size, int *pens) +{ + g2_device *devp; + int i; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_image: No such device: %d\n", dev); + return; + } + + devp->x=x; + devp->y=y; + + switch(devp->t) { + case g2_PD: + g2_image_pd(devp->d.pd, x, y, x_size, y_size, pens); + break; + case g2_VD: + for(i=0;id.vd->N;i++) + g2_image(devp->d.vd->dix[i], x, y, x_size, y_size, pens); + break; + case g2_ILLEGAL: + break; + case g2_NDEV: + break; + } + + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + +/** + * + * Quasi Pixel fake. Quasi pixel is introduced to make easier + * plotting of cellular automata and related pictures. QP is simple a big pixel as + * specified by g2_set_QP(). Coordinates are skaled accordingly, so no recalculation + * is needed on client side. + * + * \param dev device + * \param x x coordinate + * \param y y coordinate + * + * \ingroup graphic + */ +void g2_plot_QP(int dev, double x, double y) +{ + g2_device *devp; + double d; + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_plot_QP: No such device: %d\n", dev); + return; + } + + x=dtoi(x); + y=dtoi(y); + d=devp->QPd; + switch(devp->QPshape) { + case QPrect: + g2_filled_rectangle(dev, x*d-d/2, y*d-d/2, x*d+d/2, y*d+d/2); + break; + case QPcirc: + g2_filled_circle(dev, x*d, y*d, d/2.0); + break; + default: + fprintf(stderr, "g2: QP: unknown shape\n"); + break; + } + if(devp->auto_flush) + g2_flush(dev); + + __g2_last_device=dev; +} + + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_graphic.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_graphic.o new file mode 100755 index 0000000000000000000000000000000000000000..04cabbe213d12a73595c8069eb346c0952fae6c7 GIT binary patch literal 22280 zcmdsf3w)H-ng03an=qpZnE)Y>7$ic#$R*(>0-^@P1Xw8sB9~o=!;nlaI%LAk1c+79 zM#OB2LbYypwX40@)=OKfZnd@6D0ppaY3pvml4||;0!k(OuXWkg>ORl;-ZS$}Oros1 zzuoK9`InUF(E~hv6 zO7FV-I_w!-fbI&KRC&i!-N*X?tLO;=qWMpg;9 zW?1Q3XJBEx>hZL0u=&s%Ebgs4*c&YEtvg_H$hi@??lxHL4Ib2eaR9?g`r_+!kG`1K zT~)lZ=Vbe0_g01ZA@k`mnNJ7Mx?;N8P@4a~R1P@1e)Rga?rF6EF%8%)Lt0LC(kxEF zt*-fp{#iVD|IAJG4}xa@=(sWUxGD_XTZ_?KPCr#5)O0_A?_K~NM7ZmdS1`NL(`Wx`KV(SU%fNbOn!f2m4H(oMG`8%yb8jJ@JayI?-F% z*Sj8VKGAJsp7yTK4_vn&)f^rRo#8PW`d%Z*Wd;T~FpL`x-*&4L+-9Sx@qPbE=V9$B3H0VX9X)9U}GlxmyE?My(VMpt=F&gdiGBat=|QBCG-vP zO2Gbm*8uys%7GK(yk1-;Qw!7u1FrX-$399v^osOR^TGA$qvvDe$CZ!&^7`|>z5f5i z{pAegG*J6-=2_MxJ^#9M1zmCTCtt<*F9 z?(4eYcyVcQckm!!>|jkB@Zh}v=r%0W&cQi>xY83-N23qUAI^L#bG(3%g+F~?%>E2Wu7MJEc!fSV=#Qz8uX%?IdO6TSJH(h6giF?Y*^_SM|LpL4DB7Nw& zgU{>F69=C-^!&l!9D1G?S%;oK{HeY}&vnh=HD}JDo`X*wdhXY+qRcBbm(}DwyuXE* za}(Wdsp)U&1(!EU4+~!WsR`%hK1Mk$pQP}#aLY?NhP*|R2XJIi|`i5Ka1*swCdGAP~REBAHK#wpgtte&WRZ=lMbYu%tp zuWv5w`2#}wedn<@PskkK%Opn#ndeKwq<^H4`M$eg!#_&MvA&gv$)7J|v2PP=M+;fv zTg4WQ5wg_x2BR7)WSQ?$Iw}-$nr}91PqPx>dM3{BjilvqR);3%`0^<{URpHISIF9l zLN4^3!yqSF4Z4AqzB1OHWzE*)V&4IVF~wS>$!cFAgPdyZ(3Y3@##6V#x=E8ueeW`i zdDd1fyxjL4>Yi^gxt@ua_#Pp7fspHbhZxl&31fqADg9PipVz`0l^>lp1LafLO{Y$z z+iwnI`-)&C$Nyk9L-0T3v{+@=F_3?98tl!!g>ih(=|R8B^76fw<^4R2%LG-SEB|m0s`oz|+7Tfv@3P1zv}+6}TK_ zPvB9M?LaOf@&^8vJ_4=y9u`;yjxW%GT7RGioKphbFnwxZ7__njBiXLNk0CQWa1&&5 z19kWg1OoWZ3*3R)5rK{P9vK*h?@@un(9I9*MR|1K+t4Zq?1Y^$fob?28<>M^76$Hx zZc*SOa8ARtQ>r*{3ckk$iorQud38g+$hPKw8+M*Uo!2f3ybXp5JPBP(c}oCx@vW#H z_A0)<39o*8d|u;rWtT7+m?C+N?XAi_Ue9RWKZ}$io@=QxpLIi z*pu?wS{jr+S>{<@TSJ?&&veF$H`|Z+?J`E?ndr}JY*hAHRP{{E$qUb%sq87=)l^QnggdZy&JH7HLRiTtf7omGnx ztUpG>T71|G;9LX4(>$elN#&VDN9-L2IZ|ZRqhy^0eWkdDTdNBiB3qSJ zMq}36g6$}3FMFE{I#T70W6GgnP0n7vTm)kdSI!O;$pf+ zOgF%Gjj`PT<3fn>RcYh3Vtn)~H2d$2xWn25lY7w^V|IHw;_b#Nj7nLIUXeEXX=8Mn z4@P1P@N3qcFqp%zCDyyNP;EgRvEJoaZ7YbwtPsskBEGK8)~L~6q^%~}deX{+ow-Q9 zvGs%raHg`JNJW??HWqB3m8w}+(2*u;954IQ!S6T0AEiStGjiOjgtLcS4&RXAndmo6 z@JzH25`3QoUpUVXGjGtA-?DmOsGQ~1MS4K^^tx}=7QvX$5^F^;W{Bp~^q4rsGUon{ z=Hl$3Gc1cEILzJ?b0yAeWN%yXZH(BE(c&*K`z4lEUh9~g;Fzo(hjHe-1uYIV#!xs5 z>!WowMwqqQvfAL_ekMemtaM^tTeKZnUL`>{7j?L(jYUj)t<kjJE*RVpbX^%^|u*88OjN&J0mDV zNl?38LEV@Nin~ke0F(Vg%VIzUWJpktxr2HvBPc^TK^e-)l%Z;zY&`CA+>>(rJ^Hzn zeg8+xDgjZA-L!Fh%b;YjB-P*D~e-W8%mP4 z#pO1havNceUSrbk^jLSo<{gyYswj$1>C+b_A?emUj#Cv;muw?Fk* z2jKEZUfS&oF1IhZ-5LUJm1T%^PNyAk`T1GO&)MvwL+rG7Jysul_(!Jw{Ke(xFK$1E z(0&Xde%^EWQMMjb7#z>i&lw!_vurC5K5B55G=rnu5yQH~HoJPy5KbCrNR^XDL)8?8 z(X%t9ZfQ{%J!>dg0A}0i@j53J(t3`cUJj^6+hRC-^3x%0a)ngy4#^NsNDUbw8OjMM zk`a=jB%~%+NX@B`o?=Lk@^yKOZ84m0j82Divn!;V-60ubWAUdrU~aaja8I*$gVXPy zcX_%s<>^x##rya^+izRK+mj(S7XO?>#*u@k;v1MoL#`{nk8$j? 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zKh$3(c!%&G7kozeKN5UJ_{Rm`6+E5$9oU^rguN+(7YKiaV4dJqf;)+j?-G1b_-_hw z|HOJO*u;y7@N>CfLipPR9~AyC1b-#`mjzG5`-J-E3RV$ecZuM)g#UuzzX<;&!9~!e zeps-D2>s21w+sJX!5<0!Lh64hI1KMG+8HfaDmYuPR&YHL_Cta<3jc1w?+We{ + +#include "g2.h" +#include "g2_device.h" +#include "g2_virtual_device.h" +#include "g2_util.h" + +/** + * \ingroup interface + * \defgroup vd virtual device related functions + * + * Virtual device is a method to redirect g2 output to multiple devices. Here is an example: + * + * \code + * int d1 = g2_open_X11(100, 100); create first X11 window + * int d2 = g2_open_X11(100, 100); create 2nd X11 window + * + * int vd = g2_open_vd(); open a new virtual device + * + * g2_attach(vd, d1); attach d1 (1st window) to virtual device + * g2_attach(vd, d2); attach d2 (2nd window) to virtual device + * + * g2_plot(d1, 11, 11); output to the 1st X11 window + * g2_plot(d2, 12, 12); output to the 2nd X11 window + * g2_plot(vd, 13, 13); output to both X11 windows + * \endcode + * + */ + + + +/** + * + * Create a new virtual device. + * + * \return virtual device ID + * + * \ingroup vd + */ +int g2_open_vd(void) +{ + int dix; + dix=g2_register_virtual_device(); + __g2_last_device=dix; + return dix; +} + + +/** + * Attach a device to virtual device \a vd_dev. + * + * \param vd_dev virtual device (create virtual device by calling g2_open_vd() ) + * \param dev device + * + * \ingroup vd + */ +void g2_attach(int vd_dev, int dev) +{ + g2_device *vd_devp, *devp; + + if((vd_devp=g2_get_device_pointer(vd_dev))==NULL) { + fprintf(stderr, "g2_attach: No such device: %d\n", vd_dev); + return; + } + + if((devp=g2_get_device_pointer(dev))==NULL) { + fprintf(stderr, "g2_attach: No such device: %d\n", dev); + return; + } + + if(vd_devp->t!=g2_VD) { + fprintf(stderr, "g2_attach: Device %d is not virtual.\n", vd_dev); + return; + } + + if(devp->t==g2_VD) /* if virtual device */ + if(g2_is_attached(dev, vd_dev)) { /* check recurency */ + fprintf(stderr, + "g2_attach: Device %d is already attached to %d.\n", + dev, vd_dev); + return; + } + + vd_devp->d.vd->N++; + vd_devp->d.vd->dix=g2_realloc(vd_devp->d.vd->dix, + vd_devp->d.vd->N*sizeof(int)); + + vd_devp->d.vd->dix[vd_devp->d.vd->N-1]=dev; + + __g2_last_device=vd_dev; +} + + +/** + * + * Dettach a device from the virtual device \a vd_dev. + * + * \param vd_dev virtual device + * \param dev device + * + * \ingroup vd + */ +void g2_detach(int vd_dev, int dev) +{ + g2_device *vd_devp; + int i; + + if((vd_devp=g2_get_device_pointer(vd_dev))==NULL) { + fprintf(stderr, "g2_detach: No such device: %d\n", vd_dev); + return; + } + + if(vd_devp->t!=g2_VD) { + fprintf(stderr, "g2_detach: Device %d is not virtual.\n", vd_dev); + return; + } + + for(i=0;id.vd->N;i++) + if(vd_devp->d.vd->dix[i]==dev) { + if(vd_devp->d.vd->N>1) + vd_devp->d.vd->dix[i]=vd_devp->d.vd->dix[vd_devp->d.vd->N-1]; + vd_devp->d.vd->N--; + if(vd_devp->d.vd->N!=0) + vd_devp->d.vd->dix=g2_realloc(vd_devp->d.vd->dix, + vd_devp->d.vd->N*sizeof(int)); + return; + } + + __g2_last_device=vd_dev; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_virtual_device.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_ui_virtual_device.o new file mode 100755 index 0000000000000000000000000000000000000000..e498a8d38e7ebb8c961837fbbf4b9a8d35328889 GIT binary patch literal 7764 zcmb7J3vg7|c|P~C+RJLWE06$zg}qn^3k)lPiH$MEfP_GfEDHm|NsX74_Db5Y+Ld?j zVnqCijU7i`W8+L6yNsPSu}L!1rg3a%;=GBe-KNc?nNE{>rj6T)(@q?mrjN8?8W{S0 z=l)k(DP-E7nR~zUKhOW4^Ph9?-hE(aUyorJDr|fkS@wyf0ZkDQr$Gx6}_ z(5dc>PuU?e@$lLkivB8oR4SV zmkF(b{A>3zjyo|z_nZ-CgPJO=E%4P`42G zHn*|fa<6ceGFK|gt*_r&uat$Z6Ljsx;BKzJslFE#6-lUi-KlFdj7DlxqEvK#pcLtC z+!RyFp_)?jLQ|z;q5xwm)T4A8=`g-R^)_}ucfLK#q1z6JE%TL1z|aYXr(we)FJz>wq~jb zn000h=4Qmo6?|n!%y(h#M9fFQbfWfoXwG}GNKfB|tsSv%h0(l|gEPJ(_7fzY<*;>i z?SRK&^n1}%^nLU(&$x}^Ruz4jo?YW(nzW;*;Lk}2=|o*h8-$EUUm&?a$cE?_;L=$r zWK;A(_;4D9Y>pm6Oiq)KEzw&jT_j{OdXcV{2)Q!)5~FGsvOU^C=~5xrMtRyfR~Td9 znysDD<@CJVC}?tH^leJ7l8iP*S5n$4&m zJy9N=&b5ZGJ@1MR(YC{QSd+V>XE@L%fgr5zjK;9m)r%~271 zJ#-`X({NJH__*Bh2XP~J4H)&OYPr{``LBTf0b;c44!S8gQ|=br3^o5FV6KADwy$y- z-vjQ4a98dojBmJG&^O&y^euM}?zTI^FYxHq_MxG!+)abM{E1vDGoPr|Cny%L;7?hm2A*zE;>iF*oL%C~UYbg6+ z2&|SW?sb2QTMm|vbyZ^IsIror4D5@vH-WG9q$O;8|qtP$~B?TpH7brK^Z%34iRvo)T`tY5FJHGib3 zhD2t=hH0ufF$B@Ifhd_6f<%b+*k_<`tqVk*u|td~6;PXE-=M4`pti++h4ih?fZB}| ze##)?EJ@qGhqCqm!AyPvqqDf2$l^r5iYy89$mWi!NHe7-3L#>XZ!`DEQjRl!89X&% zc-w4oxjPy;y-a;xC8pOxu$Uu97kC3bTXz#cXX?_91pU`{A(ZSGXB#dAmvPWW=Wy;xhIxVhF|-Iy45<;%=P# z#yk>zMiOu}hBNjr`DeoWwbFs+tan5R^QrjKKd0zcZ8x~|0xbh#0J$^m#h;+dKcV25 z(FtWfS3;MQI+3TGz^72+^TUD9MLA{Mt4H3emVFeH8GV9BiD4{zhs2XYbir}-q!8OU z5lgj^p;+OjdYu6nzjkA|^B7h}xiqXgD&b?yUCE`7KAhb3&P2}&#isJy4yKnF2a<+DKg6Ver9-VbFy0}nrzD^ zbLC{A=qDxW6y6nT_4GpBrX$rA;0HQtM_>1qjo4~ z&3+#`q5QT-EsE8Rw8N#;U!ualhf+u8#R;#F#v#BBH$4&R7ASxULf0mA9vGvD!xk_! 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See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include +#include +#include + +#include "g2_util.h" +#include "g2_physical_device.h" +#include "g2_config.h" + + +/* + * + * Double to integer + * + */ +int dtoi(double x) +{ + return (int)(x+0.5); +} + + + +/* + * + * Transform user coord. in physical device coord (int) + * + */ +void g2_uc2pdc_int(g2_physical_device *pd, double x, double y, + int *ix, int *iy) +{ + double vx, vy; + + vx=pd->x_mul*x+pd->x_origin; + vy=pd->y_mul*y+pd->y_origin; + + *ix = dtoi(pd->a11*vx + pd->b1); + *iy = dtoi(pd->a22*vy + pd->b2); +} + + +/* + * + * Transform user coord. in physical device coord (double) + * + */ +void g2_uc2pdc_double(g2_physical_device *pd, double x, double y, + double *dx, double *dy) +{ + double vx, vy; + + vx=pd->x_mul*x+pd->x_origin; + vy=pd->y_mul*y+pd->y_origin; + + *dx = pd->a11*vx + pd->b1; + *dy = pd->a22*vy + pd->b2; +} + + +/* + * + * Transform user size in physical device size (int) + * + */ +void g2_us2pds_int(g2_physical_device *pd, double x, double y, + int *ix, int *iy) +{ + if(ix!=NULL) + *ix=dtoi(x*fabs(pd->x_mul*pd->a11)); + if(iy!=NULL) + *iy=dtoi(y*fabs(pd->y_mul*pd->a22)); +} + + +/* + * + * Transform user size in physical device size (double) + * + */ +void g2_us2pds_double(g2_physical_device *pd, double x, double y, + double *dx, double *dy) +{ + if(dx!=NULL) + *dx=x*fabs(pd->x_mul*pd->a11); + if(dy!=NULL) + *dy=y*fabs(pd->y_mul*pd->a22); +} + + +/* + * + * Transform physical device coord in user coord + * + */ +void g2_pdc2uc(g2_physical_device *pd, double ix, double iy, + double *x, double *y) +{ + double pcx, pcy; + pcx=(ix-pd->b1)/pd->a11; + pcy=(iy-pd->b2)/pd->a22; + + *x=(pcx-pd->x_origin)/pd->x_mul; + *y=(pcy-pd->y_origin)/pd->y_mul; +} + + +/* + * return a < b + */ +void g2_sort2_i(int *a, int *b) +{ + if(*a>*b) { + int t=*a; + *a=*b; *b=t; + } +} + +void g2_sort2_d(double *a, double *b) +{ + if(*a>*b) { + double t=*a; + *a=*b; *b=t; + } +} + + + +/* + * + * g2 malloc (with error message) + * + */ +void *g2_malloc(size_t size) +{ + void *rv; + + if((rv=malloc(size))==NULL) { + fprintf(stderr, "g2_malloc: Can not allocate memory\n"); + exit(-1); + } + + return rv; +} + + +/* + * + * g2 realloc (with error message) + * + */ +void *g2_realloc(void *p, size_t size) +{ + void *rv; + if((rv=realloc(p, size))==NULL) { + fprintf(stderr, "g2_realloc: Can not allocate memory\n"); + exit(-1); + } + return rv; +} + + + +/* + * + * g2 free + * + */ +void g2_free(void *p) +{ + if(p!=NULL) + free(p); +} + + +/* + * + * transform float* to double* for N elements + * + * Note: don't forget to free d + * + */ +double *g2_floatp2doublep(float *f, int N) +{ + int i; + double *d; + d=(double *)g2_malloc(N*sizeof(double)); + for(i=0;i g2_LogLevel) { + return; + } + va_start(arg, format); + vfprintf(stderr, format, arg); + va_end(arg); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_util.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_util.h new file mode 100755 index 00000000..736cb565 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_util.h @@ -0,0 +1,48 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_UTIL_H +#define _G2_UTIL_H + +#include +#include "g2_physical_device.h" + +int dtoi(double x); + +void g2_uc2pdc_int(g2_physical_device *pd, double x, double y, + int *ix, int *iy); +void g2_uc2pdc_double(g2_physical_device *pd, double x, double y, + double *dx, double *dy); +void g2_us2pds_int(g2_physical_device *pd, double x, double y, + int *ix, int *iy); +void g2_us2pds_double(g2_physical_device *pd, double x, double y, + double *dx, double *dy); +void g2_pdc2uc(g2_physical_device *pd, double ix, double iy, + double *x, double *y); +void g2_sort2_i(int *a, int *b); +void g2_sort2_d(double *a, double *b); +void *g2_malloc(size_t size); +void *g2_realloc(void *p, size_t size); +void g2_free(void *p); + +double *g2_floatp2doublep(float *f, int N); + +enum g2_log_level {Error=1, Warning, Verbose, Debug}; +void g2_log(enum g2_log_level log_level, const char *format, ...); + +#endif /* _G2_UTIL_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_util.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_util.o new file mode 100755 index 0000000000000000000000000000000000000000..39088cea08e39b1b16025b96811d21e735096874 GIT binary patch literal 9632 zcmb7K3v^WFo&WC4Br_zF+<{C&z#yXph!64rmIX>B5CVw=4B>fH940e2$t;tZaUN;# zQ7RmiG@{stt#z%qufBB4y0vQ8?NXsC?e3}Dhcz`>wcT1h(xbcGD(C3J{(j&6-3*OG^u)3>zHcXKK9##XM7X4 zpEIBAJU3BB*<`10pi21%#yUTo82<2;-Df9;&y9DUJ$>>>Zh?aR)`Mpn#&`RsI@%{U z`KLO%CN~8qPEU5UPHqekm-7*tI6bxd&8ddQH$Oao{`^$uo8#LXCO6iPxh6ZB9O?M> z(3tDssfHVNpFA?6jy$uFjU)berw`Us?K*tBgl})1>|*$KhHno|&7SP4pKNa$?+i`V zU*v!AOmHlJc0AuOw)?-3=b`t;ZvSxn_E4^Nsv|JDv3=rorY)I`l^;4!Mg8Q)E-Hcr zg?Aj@2y^>~V`p}s9DA=MzwHf7aZ~8fPjgjM?SaWIi8=ewX$tBmyCl}E-6u=>6Pg_M zPqjBq4zpb8z~r7*Vm%-2=+B(BTm-`4Tn{_*MK?iJ5|+B0U1)v#pWS>V)b z6YAxkGNxQ8`s=U0_SKOJ5VNLczg<4|-qg!eFMp&y^~itBV~@?D6FJxElh1n^8SN21 zzBdn#v2BgMv2~69r#P8Fc=SNR48wU|(?`BbV?BQm&rh3=3(L4V?9)0@PoqbNr5J?o zBVpgJI$C5011wP9cf>Qrq@2FB{q$|`gy;ULh8Nea_| ztNp9|NaAfDDhNcqI6>4RH=jy1L1^^j@ntZspFrpNMJq`60X#fj_g}!y@VS5Qf!6De z10Z}IV3fNj=~Cv2Cv(bE=01lYzA|?gLioI{37AZ~_ZCL_H-zw%xkj<;O*ZFAooo(t_Qg0Det|ETy1<_vmWmgi03nf^?6@ng8^av-p|l@ zy08K7afI~E5H{$|F>;Nt_1>+>$rlv1!P`r1t*{~QEH*S#*hcToY^Yw?Chyy9XqK>7 zdsou<5`($A=CyjKGx8kci<({P{StlWN{^O%FQs;#u&cbcGRgTyN_Vi`yMWp&jB7Nz z&iiMKe5KK&+4bI8O!6w@K^=L6H%i|Y<6D~T^4`IQmK%3y;~wvg^u5Mlab5Gad81@k z3%kpkhS;}8(zwxkE!*ud{!Sb3Q9e(Z=M$i(ahO~u5V-uRjo|HZtC+_;9xG>uU&HP9 z{e9(3pzk|&2~_1H%Ybr9?~8^I~_lW5p5&w+NCmx6YieRz7z&%wUTyb&hl z=KYX(&EK&eW-aJxrV0BBa}3W)^F>7SoBs-VmH8fQs?DF_X`1`+44Bv9Io(`{=M3`{ zENjd#yn<#2B(>%#c-5J6AfIV|8}fQ{F*2WJehre@W*H=xnCxbQIStP_=EIO&s$A@d z`=Ot~sQMJ*+zXw@HQW4i2$VS=F%9MVEEKMWZ{b<~J{~LK;&aUn42&vQh{eES2@K?u z%5|9w4z76~HJt>DJ_BW?kLwLEuFHSI7(axr8Emg>ejpu>Dc1s7ae;I!ty~N3S>vhn zB7avCvvSSz1qKF`>k7KM=J^AWwl?Lul0)U17YIZaFD`KPfqtm2vQ?o#KQzKLRep`$ zi)>YEWgEKTYPPxMmEWhX#pc>8YuIS3&2^y*K5AF7xwaaR)gR#TBv?<`BJ)1PG0de@ znhA8vZJwn@)yzZw#&JY4>?H@Cx*E5!Jvge2%XReoe5&>c?N;&8YH$y{)3!;+l+mnp zTWN1+dY?bIuRsTbaVT0oPuIR+915Z9Mj&rv12ab;)s(Rt{rEBRF7vS5wMIF-e$U+3 z8b={`uGnh3Znc-Kw%b|iR)r1*V^FNo{(Zq1;@fnuZnc9Bb!=5rXpMr}8`#<&Cc4dd z5iKob!`p-GV_&h4eI>04ZTE4j?&A*KN1NWMYQN2x&$7NzR8FZq#h8&|4Up zU(y4c-lA$}c@ZwjJTnI4-CvBEmYA%0+6l^{3ln6$ZkC`B+hlKDItqD~4j>`dq^iB1 zEp5Pf7@skYp%osWP?3l-_Uq1W3HCeW*80bx{4VagoH7n@_)yXZ8Q>3~jKjtW=-wy< zxJxIY1K4C={mW2tsWZT5nG3d$7a3p)Gx(C;n%{+fB~-@tS=X|v_s?hW-kF&ZWqg^7 z(&$w+0ld(S3Oap5J8?(6Pdf$E%J{l%X8V7=#Q&S(U%Q0<+#QVX8OPxFc)|B+r-@r> zQbzd;277V>E8EZ=G}on?s^QS$5Z<} zgZkMmlmftm2s%2#xW9Y}`MB=$&FW^nU;YVYy))_}nL%YtyZ}zkz6%!Kd-zf@jM;Ng zDDS<(tcBWp)Miu;8kc&NVT=!|EAZ4GZ$>r~RW12!rX`VzMiMQFcz?@aG};nhwtU&5 zbaYW7p3ILf8cgO}mNYMIZfl7rqltXXvRyuoY3YyWvPumu4(D_6L~~T3T`=jPec3n~ z2*<3Ec+_eh5;->K_^8cgbFr8;02*C!+_f1L=&-E-9Z!KojgYEC=JutnETkv}b`h3E zxi2?juEv17GJ5l>*r!)*-TChFmCLVoSNdLGv3i*n>;Mz>U3%q;l~?<^x_n*k3g7k> z_jEni^_;unsukCWk#FzKEAQz3>WbKJo_1F}IqIK=Uj=)d zvHmY31PkEir;wqH+kAeH=P+6bLgrlD#@AH)4!PD=mB}Z#;?}*RM858zyWqnOc3Fuo z1ezDO!kxICSnKcftUp-Rbr%X>@a5LV*p7{p#~#Q_V>)>pgPeyo$G$X=6VNRv(K)fW z^soIGc{@gV%g4x%K|Z5I-T<1{3CNcKowhpcQxWj|XrZTz3 z;ke>9Twr60n<`j)A}Q{W;AF}u?tNefGM1&dkC9HKBDwTpyQQ=`Y)ccVL39jftwQ(o zn$a@n3y2H?bPq=cEfQPuR%Tys3Z1nwDx4ice*O6Y74E(+j5)nGoKs;~U9`d#R;rcB zsDV^wI06e8!zpYfV+^^~%JsyP*3Nh=H>7r0nf_GP(l(#U#B-Lm$|tk&!K4)nvB+#7 zno4C<%TQ|AYT0XLa#r@1mJL=iZndn9CtG&Jtz{+mCLT!+V#eqKMWTE2>2QC9#YhbdWG&su z*2svZIx`t`KRggmSjiNd-eBc=*L6jbv4o{Fwc~Xr67e+M!`QQ<;gLu<5zppSHhzo6 zal$BI%Eas@5JV@+XfmN?UP92F+)MdIvnZUjMs-e3I~z7{4|Rm}yFu-YWRg;>izfpj zt>3=6dsle#_MRRU9g1WWUOX5P=PeN)PT{SB*%?k)BUYkhF4)y@5>MwcOshMY>)>=? 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See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#include +#include "g2_virtual_device.h" +#include "g2_device.h" +#include "g2_util.h" + + +/* + * + */ +g2_virtual_device *g2_create_virtual_device() +{ + g2_virtual_device *rd; + + rd=g2_malloc(sizeof(g2_virtual_device)); + rd->N=0; + rd->dix=g2_malloc(sizeof(int)); /* later we use realloc */ + return rd; +} + + +/* + * + */ +void g2_destroy_virtual_device(g2_virtual_device *vd) +{ + g2_free(vd->dix); + g2_free(vd); +} + + + +/* + * Return 1 if dev is attached to vd + */ +int g2_is_attached(int vd, int dev) +{ + g2_device *vdp, *devp; + int i; + + if(vd==dev) + return 1; + + if((devp=g2_get_device_pointer(dev))==NULL) + return 0; + + if((vdp=g2_get_device_pointer(vd))==NULL) + return 0; + + if(devp==vdp) + return 1; + + if(vdp->t!=g2_VD) + return 0; + + for(i=0;id.vd->N;i++) { + if(vdp->d.vd->dix[i]==dev) + return 1; + if(g2_is_attached(vdp->d.vd->dix[i], dev)) + return 1; + } + + return 0; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_virtual_device.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_virtual_device.h new file mode 100755 index 00000000..16fb6a79 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_virtual_device.h @@ -0,0 +1,32 @@ +/***************************************************************************** +** Copyright (C) 1998-2001 Ljubomir Milanovic & Horst Wagner +** This file is part of the g2 library +** +** This library is free software; you can redistribute it and/or +** modify it under the terms of the GNU Lesser General Public +** License as published by the Free Software Foundation; either +** version 2.1 of the License, or (at your option) any later version. +** +** This library is distributed in the hope that it will be useful, +** but WITHOUT ANY WARRANTY; without even the implied warranty of +** MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +** Lesser General Public License for more details. +** +** You should have received a copy of the GNU Lesser General Public +** License along with this library; if not, write to the Free Software +** Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA +******************************************************************************/ +#ifndef _G2_VIRTUAL_DEVICE_H +#define _G2_VIRTUAL_DEVICE_H + +typedef struct _g2_virtual_device { + int N; /* number of attached devices */ + int *dix; /* index of attached devices */ +} g2_virtual_device; + + +g2_virtual_device *g2_create_virtual_device(); +void g2_destroy_virtual_device(g2_virtual_device *vd); +int g2_is_attached(int vd, int dev); + +#endif /* _G2_VIRTUAL_DEVICE_H */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_virtual_device.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/g2-0.70/src/g2_virtual_device.o new file mode 100755 index 0000000000000000000000000000000000000000..b46783b63302cd32c5418efbf8cb540878855337 GIT binary patch literal 6916 zcma)A4Qw366`tMO^PbN>uj9YijzgR{0mq5Yc5s6e()`)6W8@kqjzjoKj`Q7~z2tm* z-0c~ghNcigaNQDwpemHAP|>PXfM@{;S|mb43u-H5V zJ{wRwy4`Qy@4PqjW_E86ZtLq-6h(MV5k4_X39)N|D`}U|D5^xcrz&x1>g3>|)7q=r z@&M?+UATDh;;T|HbsRj+<4tvHQ-8ef`n|_le|m3V8Z2$Ow3yl(xc2(JACvLW^ECR@ z$wQ~Br}lmdwW-@KOy5>Kl{>fYyt8I%0~`Fh?bzY7&a$aGrjLVu&na7XLYg~;ZO0B> zsXE5g*=ab*otwVx!qn-#$EQ03ZD*%T55M`fwtK(z?4=av^k!|{hNqnsQwNr75QCi7 zp7!E8d@NTCX7{?*gYUE*JN1loe(DKjfl^vfhWm<=@*-c!q7ot0<-%7|RJ5^32p_ru zx2siwyT0hkqFzjz-w;KzQ&6rb<)lp#A@q=|glmhi4>G^$D$`P7h{Rrj(zj_~h z26XMOP$@iWlg10M)%;qwADnx4&-(UjG=_SFhAk*)1nh&+{d!pMBp-#!)g*2Z`lIBz zM7dj%ntlZS0tS--JxJ10CX4m^h+M#AseU_L2FjSM(7z5JfpR9R^=lDRpn}Ody_ckw zOxEk?$<;z8m+QZvsH&N4)K`(ThRN0XS+ZTEjDo8+wCYRA^I|0>$#(tEWV?hj>d+fW z+Q8%ny^n%ip~T@rZP={0l60kVxg@*vjg)VbvPF{JdJPS({^Q@bu2xe&X=iDr{;657s1$Ws3!mqVK*RMSQCq)z=EqC$lxDmGrjG~9~ zxtEKAmq9;3F4d|~zfc!)1%%?(gixzVsy1jaCcgGCl2L2OMae1LehE@5*lRQ(2w`l+ zO%Wx}gSiYs&A-H$1RgX}QXIq}iqQd%YMg5QT zV+giE;}5tO8E?V1*mxT{A>&=>lo(IpZWuS>UTQSpzQ8ENz07zGn&rmhu&OZXz^OET z467<*8~6*2e}P|ZY{1ml7$+gEHLAg1WMDv1XB6VT*!UPamk5m#@qdqUEqNcBk3pts zwZ>Cm2;%}ciqLKbXm!VNFEB95ov;jOOG1eWq1Dr5U_XTtxs=eB)yDI_<(IwOaS4jT6(T49`kP%++vL={>E2;b5( zxR-6EjC@Vy>A3JU5>Y;m-pcLhVUWK=#jm{z_XWqnxeDg1eal0R@U5VMXqKsFeLP)S z2)0ctq$CgmpYtpZO$y&?H};BP3|@TA?gZC`b_~FVbFL3kb^BW0#DHo;qtI?Z$Jg2q zhZSdVQ<`9^ESA9`zE)hyP-P}AluL-G42r56ochXhlnSf@HmIxoPr zvQ{1nq(e^!Wk~9Mi9%Bb7skzTp}52~mE))bU*lZz%Jh|G$a;TXMWeU?4SY}WF~^yp;Pip^Skd~6eIBFvPFStoAU=puupHSBer z$+VdTm+DFQA;a3#DbDl5%^%)$^ZK9o3LjrK5cu*{4>!?o^{$pCU(wCJiC+a)-yS${ zSC^_ITbPvM!fV<^MJNXX#hP|EnDjc~HCnVSC4s~0){wvJkZ(pt{Q7w^qN&jWK88!$ z^@RN0hy2|~eBF0p>ctJXWUS(TEc@$NAIw-RV@4fw-h2uwF$m*k*2&nD^QBZ-kXqSD z)N!J*Q8NzDIJ{>3(`at62!+WGrM$hPhPM8cCV)dU~7jtmLRM+s=rVQG3j6*>7eXGka@GkD0Q}maSH*Ww&Lf zQqi6LTV{LBZQ->o;3Vt}=F7~qjI3#H4PVhJPtc2-1ljtw26A?ULEZD-Ug8?zY;;@6q#56pv7)Jwr0LFhG`2sNjtob$pzTB=Ysx?eqvJA(-CZJ* zu##rVrlEUGXP|3)G!;*pSsA1Bw=J2p(qxVWMBT+*XHXw>G886yGB~M_g=24tdsF*G zBxO#>5j`(G{X_Mg^_Pd+!);_aJ0bJS2Ey*4{@y*2{-M4;5gU!72AEfj}a5pGsq zSZOCi9(z+xC)EPF`LzymW@6AENZP1Yn7RusW+#;@YcevHOU~va$AOVMzdNzm?gWFi z1(gk$i z{VB!ny3K3`INpj%8_C!?>{59exKlcl1w|6Elku6Uz!{CoMq1syecNb6_~?q#p2*Un zGBH#9P;r-=7I?y48K{3Yb2kNEkuNv}@o2DfvLL<02e1VwD4bq=w#W&`BMnEwyixGT zf;lEc&=R@XN1#rb$W4wFkL5C0z+`Sr&L2;x9ARxcoshXyE^Ef2h`i`Ll*J`_Iy=|b zH)3!n*~u{!575cDIO_E>W-{#1z6!^qPE>@4vsrY_;oL|hIy{`gb3aTfF2_nG z?0h;&3!W!WWTInp80p+_3M{ysbrQ{>;)&(@L?9xZvK=#wh?}!`oa`6jm_0UTVwL~@ zwgjs5OvRH)w#~TbKYQp|OKlM@dd2qIomE0~fT+Ml_VnbUuP-Z@mQQ%}+ew($yeHf$ z@JRoE>CrPg-v#+I^B7)t>pZ;&@xZ31wbwkojbP;G@gnj#hae~qQup%MiN0rpu4pEs zJcifp2Rq;2v$bws6yhbv*9>t}5OyFJQEU%FcwV&eh`b3jn8FjdMGWt~L)f9=o1HGTK4uPjf z=)Tjr!dH;MW-u#3dU;SNlxw~}d`=SwT@!it{N=Ge!`H+o^Z{t5&HcJb{_{s5+N%cF z#3%A54lLiyZuR6;X|v5IDFG1~ae{*$yw87~gJ3M0#0xK}e8FP|l0?Ro zPs({OAtR>4FFkno!$T2o(!xLpDsByoTL>`?5D66@I`3e7mk@>5$8tI|6f6(Tu!2IS zToe=*?FT~oU!tJ)7c(wpyp*w-v7PZs#;uIKjMp&I`9S_m#x&zCj1(uyk1{^Q_yb0{ zk03wB^c##P82`aYe>2HX5el5JmT@Ix2V)Q8ZbmwrN#9{S#7G}IiT^0$(~K`MzRvgo z<7vk8jP&i2>}we5nJL7uB&5YfQeT+L9_b~2bj5FTEm}VSjJivGdA%MKd&ajJKVUq~xD-bf>9;cOV*DZFGmI}Y(zguKr?1|Grx^du zsA4Y>KfqYRSi!i6aggyr#^)GcVSJ161R>V)FO27zuVUj8zkqQGA;xWDI?Q-I^KWH5 r!uUJdAF!AE8^02G0(uwIFvmB1_g#a~J1_nV7x{J~ literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/install-sh b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/install-sh new file mode 100755 index 00000000..11870f1b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/install-sh @@ -0,0 +1,251 @@ +#!/bin/sh +# +# install - install a program, script, or datafile +# This comes from X11R5 (mit/util/scripts/install.sh). +# +# Copyright 1991 by the Massachusetts Institute of Technology +# +# Permission to use, copy, modify, distribute, and sell this software and its +# documentation for any purpose is hereby granted without fee, provided that +# the above copyright notice appear in all copies and that both that +# copyright notice and this permission notice appear in supporting +# documentation, and that the name of M.I.T. not be used in advertising or +# publicity pertaining to distribution of the software without specific, +# written prior permission. M.I.T. makes no representations about the +# suitability of this software for any purpose. It is provided "as is" +# without express or implied warranty. +# +# Calling this script install-sh is preferred over install.sh, to prevent +# `make' implicit rules from creating a file called install from it +# when there is no Makefile. +# +# This script is compatible with the BSD install script, but was written +# from scratch. It can only install one file at a time, a restriction +# shared with many OS's install programs. + + +# set DOITPROG to echo to test this script + +# Don't use :- since 4.3BSD and earlier shells don't like it. +doit="${DOITPROG-}" + + +# put in absolute paths if you don't have them in your path; or use env. vars. + +mvprog="${MVPROG-mv}" +cpprog="${CPPROG-cp}" +chmodprog="${CHMODPROG-chmod}" +chownprog="${CHOWNPROG-chown}" +chgrpprog="${CHGRPPROG-chgrp}" +stripprog="${STRIPPROG-strip}" +rmprog="${RMPROG-rm}" +mkdirprog="${MKDIRPROG-mkdir}" + +transformbasename="" +transform_arg="" +instcmd="$mvprog" +chmodcmd="$chmodprog 0755" +chowncmd="" +chgrpcmd="" +stripcmd="" +rmcmd="$rmprog -f" +mvcmd="$mvprog" +src="" +dst="" +dir_arg="" + +while [ x"$1" != x ]; do + case $1 in + -c) instcmd="$cpprog" + shift + continue;; + + -d) dir_arg=true + shift + continue;; + + -m) chmodcmd="$chmodprog $2" + shift + shift + continue;; + + -o) chowncmd="$chownprog $2" + shift + shift + continue;; + + -g) chgrpcmd="$chgrpprog $2" + shift + shift + continue;; + + -s) stripcmd="$stripprog" + shift + continue;; + + -t=*) transformarg=`echo $1 | sed 's/-t=//'` + shift + continue;; + + -b=*) transformbasename=`echo $1 | sed 's/-b=//'` + shift + continue;; + + *) if [ x"$src" = x ] + then + src=$1 + else + # this colon is to work around a 386BSD /bin/sh bug + : + dst=$1 + fi + shift + continue;; + esac +done + +if [ x"$src" = x ] +then + echo "install: no input file specified" + exit 1 +else + : +fi + +if [ x"$dir_arg" != x ]; then + dst=$src + src="" + + if [ -d $dst ]; then + instcmd=: + chmodcmd="" + else + instcmd=$mkdirprog + fi +else + +# Waiting for this to be detected by the "$instcmd $src $dsttmp" command +# might cause directories to be created, which would be especially bad +# if $src (and thus $dsttmp) contains '*'. + + if [ -f "$src" ] || [ -d "$src" ] + then + : + else + echo "install: $src does not exist" + exit 1 + fi + + if [ x"$dst" = x ] + then + echo "install: no destination specified" + exit 1 + else + : + fi + +# If destination is a directory, append the input filename; if your system +# does not like double slashes in filenames, you may need to add some logic + + if [ -d $dst ] + then + dst="$dst"/`basename $src` + else + : + fi +fi + +## this sed command emulates the dirname command +dstdir=`echo $dst | sed -e 's,[^/]*$,,;s,/$,,;s,^$,.,'` + +# Make sure that the destination directory exists. +# this part is taken from Noah Friedman's mkinstalldirs script + +# Skip lots of stat calls in the usual case. +if [ ! -d "$dstdir" ]; then +defaultIFS=' + ' +IFS="${IFS-${defaultIFS}}" + +oIFS="${IFS}" +# Some sh's can't handle IFS=/ for some reason. +IFS='%' +set - `echo ${dstdir} | sed -e 's@/@%@g' -e 's@^%@/@'` +IFS="${oIFS}" + +pathcomp='' + +while [ $# -ne 0 ] ; do + pathcomp="${pathcomp}${1}" + shift + + if [ ! -d "${pathcomp}" ] ; + then + $mkdirprog "${pathcomp}" + else + : + fi + + pathcomp="${pathcomp}/" +done +fi + +if [ x"$dir_arg" != x ] +then + $doit $instcmd $dst && + + if [ x"$chowncmd" != x ]; then $doit $chowncmd $dst; else : ; fi && + if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd $dst; else : ; fi && + if [ x"$stripcmd" != x ]; then $doit $stripcmd $dst; else : ; fi && + if [ x"$chmodcmd" != x ]; then $doit $chmodcmd $dst; else : ; fi +else + +# If we're going to rename the final executable, determine the name now. + + if [ x"$transformarg" = x ] + then + dstfile=`basename $dst` + else + dstfile=`basename $dst $transformbasename | + sed $transformarg`$transformbasename + fi + +# don't allow the sed command to completely eliminate the filename + + if [ x"$dstfile" = x ] + then + dstfile=`basename $dst` + else + : + fi + +# Make a temp file name in the proper directory. + + dsttmp=$dstdir/#inst.$$# + +# Move or copy the file name to the temp name + + $doit $instcmd $src $dsttmp && + + trap "rm -f ${dsttmp}" 0 && + +# and set any options; do chmod last to preserve setuid bits + +# If any of these fail, we abort the whole thing. If we want to +# ignore errors from any of these, just make sure not to ignore +# errors from the above "$doit $instcmd $src $dsttmp" command. + + if [ x"$chowncmd" != x ]; then $doit $chowncmd $dsttmp; else :;fi && + if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd $dsttmp; else :;fi && + if [ x"$stripcmd" != x ]; then $doit $stripcmd $dsttmp; else :;fi && + if [ x"$chmodcmd" != x ]; then $doit $chmodcmd $dsttmp; else :;fi && + +# Now rename the file to the real destination. + + $doit $rmcmd -f $dstdir/$dstfile && + $doit $mvcmd $dsttmp $dstdir/$dstfile + +fi && + + +exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/man/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/man/Makefile new file mode 100755 index 00000000..c00b9e07 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/man/Makefile @@ -0,0 +1,334 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# man/Makefile. 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The pairwise model +is based on the following edit operations on sequence and structure: + +.br +\fIbasepair replacement/match:\fP A basepair, INCLUDING the paired bases, is substituted by another basepair. +The scoring contribution is p_m. +.br +\fIbasepair bond deletion:\fP A basepair bond WITHOUT the paired bases is removed. The scoring contribution is p_d. +.br +\fISequence edit operations:\fP Base match/mismatch and base deletion give the scoring contributions b_m and b_d, respectively. +.br + +In the multiple alignment mode (-m), parameter p_m is the score for matching a basepair bond WITHOUT the paired bases. +Thus, the score for a whole basepair replacement is p_m+2*b_m. For more information about multiple alignment refer to +the description of parameter -m. + +.SS Input +RNAforester reads RNA secondary structures from stdin by default. +It accepts sequences and structures in Fasta format, where matching brackets symbolize base +pairs and unpaired bases are represented by a dot. A line containing the primary sequence +can precede the RNA secondary structure(s). An example is given below: +.br + + > test + accaguuacccauucgggaaccggu primary structure + .((..(((...)))..((..)))). secondary structure +.br + +All characters after a "blank" are ignored and all '-' characters are removed. +The program will continue to read new +structures until a line consisting of the single character @ or an end of file +is encountered. Input lines starting with > can contain a structure name. + +Option -f=filename let RNAforester read the input from file. Results files +are then written to files prefixed by filename. + +.SS Output +Alignments in ASCII format are written to stdout. Option -2d generates postscript +drawings of structure alignments. + +.SH Options + +.TP +\fB-d\fP +Calculate distance instead of similarity. In contrast to similarity, scoring contributions are minimized. +The scoring parameters must not be negative and equal structures achieve a distance of zero. This +parameter can not be used in conjunction with multiple alignment, where relative similarity is computed. + +.TP +\fB-r\fP +Calculate relative score, defined by sr(a,b)=2*s(a,b)/(s(a,a)+s(b,b). +Relative scores are upper bounded by 1 which is the score for equal structures. + +.TP +\fB-l\fP +Calculate local similar structures. The term local refers to subwords of +the input sequences and structures. If parameter \fI-so\fP is used suboptimal +solutions are calculated. This does not mean suboptimal solutions of the +same local structures, but different substructures which do not include each other. + +.TP +\fB-so=int\fP +Calculates suboptimal local alignments within int% of the optimum. This option requires +option \fI-l\fP. + +.TP +\fB-s\fP +Calculates small-in-large similarity, i.e. the best alignment of the first structure against all +substructures of the second structure is computed. + +.TP +\fP-m, -mc=double, -mt=double, -cmin=double\fP +Multiple alignment mode. Multiple alignments of structures are calculated in a progressive +fashion. First, an all-against-all comparison of structures is performed (relative scores) and afterwards +structural alignments are joined along a guide tree (the guide tree is constructed dynamically). +If the best score which a single structure or structure alignment can achieve by aligning to all others +is below cutoff value \fI-mc\fP, it is not joined and put into the results list. Thus, a multiple +structure alignment can produce a list of alignments. The main purpose of parameter \fI-mc\fP is to +identify alternative and wrong structures produced by structure predictions. The default value for +\fI-mc\fP is zero, as this separates similar from dissimilar in a similarity scoring model. + +In each step in the multiple alignment calculation, the best scoring pair is joined and then the guide tree is +adjusted. To speed up computation, parameter \fI-mt\fP defines a threshold whereas, if this is exceeded, +multiple pairs are joined and then the guide tree is adjusted. + +Besides sequence and structure alignment, a consensus sequence and structure is computed. The minimum pair +frequency probability for a basepair in the consensus sequence is controlled by parameter \fI-cmin\fP. + +The console output could look like (just a part): +.br + + * * **** + * * **** + ** * **** + ** * **** * + ** * **** ******** **** + ** * **** ******** **** + ** * **** ******** **** + **************** ** * **************** ****** + **************** ** **************************** + **************** ** **************************** + ggggcuauagcucagcugggggagcuauagcucagcugggagcgggga + .((((....))))....((.(.(((((..((((........))))... + ************************************************ + **************** ** **************************** + **************** ** ** ************************* + **************** ** * *************** ******* + ** * **** ******** ***** + ** * **** ******** ***** + ** * **** ******* *** * + ** * **** * + * * **** + * * **** +.br + +The number of * above the primary sequence shows the frequency of the base. +Each * stands for 10% frequency. Accordingly, the number of * below the +secondary structure show the frequency of the occurrence of a paired or unpaired +base. + +The guide tree is written to a file "cluster.dot" in \fIdot\fP format. If a filename was +specified by parameter \fI-f\fP the filename is "filename_cluster.dot". Refer to +\fIhttp://www.research.att.com/sw/tools/graphviz\fP for more details about the dot format +and tools. + +.TP +\fI-p, -pmin=double\fP +Structures (in fact, a consensus of compatible structures) are predicted from the partition function +which is calculated using the Vienna RNA library [3]. Structure lines in the input are ignored. +\fI-pmin\fP is the minimum frequency of a basepair which must be exceeded to be considered for the +prediction of structures. + +.TP +\fI-pm=int,-pd=int,-bm=int,-br=int,-bd=int\fP +Scoring parameters. Refer to Section DESCRIPTION. + +.TP +\fI--RIBOSUM\fP +Uses the base and basepair substitution matrix RIBOSUM85-60 matrix as proposed in [4]. +Requires pairwise alignment model. + +.TP +\fI-2d\fP +RNAforester provides different types of visualizations for pairwise and multiple alignment. + +\fBpairwise alignment\fP +Since bases paired in a structure S1 can be aligned to bases unpaired in a structure S2, the presentation of a common secondary structure leaves some choice. For an alignment of those structures, an RNA secondary structure "$S2-at-S1" is drawn that highlights the differences as deviations of S2 from S1, or vice versa, "S1-at-S2". Both are alternative visualizations of the same alignment. +Bases printed in black show structure elements that occur in both structures with the same sequence. Sequence variations are displayed by using red letters. Bases or base pairs that can only be found in S1 are printed in blue, while bases that only occur in S2 are printed in green. + +The drawings are written to files "x_n.ps" and "y_n.ps" where n is the number of the alignment. n enumerates the suboptimal solutions if option \fI-so\fP is used. +The region of local similarity are highlighted in the original structures in the drawings "x_str.ps" and "y_str.ps". + +\fBmultiple alignment\fP +Each cluster of the result list of a multiple alignment is visualized in two alternative drawings, written to the files "filename_cons_n.ps" and "filename_n_.ps" +if option \fI-f\fP is used. In both plots, the consensus structure is shown. The lighter a basepair bond is drawn, the less frequent does it exist in the structures. Bases or basepair bonds that have a frequency of one hundred percent are drawn in red color. In "filename_cons_n.ps", the most frequent base at each residue is printed, +with the base frequency indicated by grey-scale. In "filename_n.ps", the frequencies of the bases a,c,g,u are proportional to the radius of circles +that are arranged clockwise on the corners of a square, starting at the upper left corner. Additionally, these circles are colored +red, green, blue, magenta for the bases a,c,g,u, respectively. The frequency of a gap is proportional to a black circle growing at the center of the square. + +Parameters \fI--2d_hidebasenum,--2d_basenuminterval=n,--2d_grey,--2d_scale=double\fP effect the drawings of alignments and consensus structures as implied by their names. + +.TP +\fI--score\fP +Only the optimal score of an alignment is printed. This option is useful when RNA-forester is called +by another program that only needs a similarity or distance value. + +.TP +\fI--fasta\fP +Alignments are printed in Fasta format + +.SH REFERENCES +[1] Jiang T, Wang J T L and Zhang K, (1995) +Alignment of Trees - An Alternative to Tree Edit, +Theoretical Computer Science 143(1), 137-148 + +[2] Hoechsmann M, Toeller T, Giegerich R and Kurtz S, (2003) +Local Similarity of RNA Secondary Structures, +Proc. of the IEEE Bioinformatics Conference (CSB 2003), 159-168 + +[3] Ivo L. Hofacker, Walter Fontana, Peter F. Stadler, L. Sebastian Bonhoeffer, Manfred Tacker, and Peter Schuster, (1994) +Fast Folding and Comparison of RNA Secondary Structures, +Monatsh.Chem. 125: 167-188. + +[4] Klein R.J. and Eddy S.R., (2003) +RSEARCH: finding homologs of single structured RNA sequences, +BMC Bioinformatics. 2003 Sep 22;4(1):44 + +.SH VERSION +This man page documents version 1.4 of RNAforester. + +.SH AUTHORS +Matthias Hoechsmann +.SH BUGS +I hope you wouldn't find them. +Comments should be sent to mhoechsm@techfak.uni-bielefeld.de +.br + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing new file mode 100755 index 00000000..6a37006e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/missing @@ -0,0 +1,336 @@ +#! /bin/sh +# Common stub for a few missing GNU programs while installing. +# Copyright (C) 1996, 1997, 1999, 2000, 2002 Free Software Foundation, Inc. +# Originally by Fran,cois Pinard , 1996. + +# This program is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2, or (at your option) +# any later version. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. 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PROGRAM [ARGUMENT]... + +Handle \`PROGRAM [ARGUMENT]...' for when PROGRAM is missing, or return an +error status if there is no known handling for PROGRAM. + +Options: + -h, --help display this help and exit + -v, --version output version information and exit + --run try to run the given command, and emulate it if it fails + +Supported PROGRAM values: + aclocal touch file \`aclocal.m4' + autoconf touch file \`configure' + autoheader touch file \`config.h.in' + automake touch all \`Makefile.in' files + bison create \`y.tab.[ch]', if possible, from existing .[ch] + flex create \`lex.yy.c', if possible, from existing .c + help2man touch the output file + lex create \`lex.yy.c', if possible, from existing .c + makeinfo touch the output file + tar try tar, gnutar, gtar, then tar without non-portable flags + yacc create \`y.tab.[ch]', if possible, from existing .[ch]" + ;; + + -v|--v|--ve|--ver|--vers|--versi|--versio|--version) + echo "missing 0.4 - GNU automake" + ;; + + -*) + echo 1>&2 "$0: Unknown \`$1' option" + echo 1>&2 "Try \`$0 --help' for more information" + exit 1 + ;; + + aclocal*) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified \`acinclude.m4' or \`${configure_ac}'. You might want + to install the \`Automake' and \`Perl' packages. Grab them from + any GNU archive site." + touch aclocal.m4 + ;; + + autoconf) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified \`${configure_ac}'. You might want to install the + \`Autoconf' and \`GNU m4' packages. Grab them from any GNU + archive site." + touch configure + ;; + + autoheader) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified \`acconfig.h' or \`${configure_ac}'. You might want + to install the \`Autoconf' and \`GNU m4' packages. Grab them + from any GNU archive site." + files=`sed -n 's/^[ ]*A[CM]_CONFIG_HEADER(\([^)]*\)).*/\1/p' ${configure_ac}` + test -z "$files" && files="config.h" + touch_files= + for f in $files; do + case "$f" in + *:*) touch_files="$touch_files "`echo "$f" | + sed -e 's/^[^:]*://' -e 's/:.*//'`;; + *) touch_files="$touch_files $f.in";; + esac + done + touch $touch_files + ;; + + automake*) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified \`Makefile.am', \`acinclude.m4' or \`${configure_ac}'. + You might want to install the \`Automake' and \`Perl' packages. + Grab them from any GNU archive site." + find . -type f -name Makefile.am -print | + sed 's/\.am$/.in/' | + while read f; do touch "$f"; done + ;; + + autom4te) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is needed, and you do not seem to have it handy on your + system. You might have modified some files without having the + proper tools for further handling them. + You can get \`$1Help2man' as part of \`Autoconf' from any GNU + archive site." + + file=`echo "$*" | sed -n 's/.*--output[ =]*\([^ ]*\).*/\1/p'` + test -z "$file" && file=`echo "$*" | sed -n 's/.*-o[ ]*\([^ ]*\).*/\1/p'` + if test -f "$file"; then + touch $file + else + test -z "$file" || exec >$file + echo "#! /bin/sh" + echo "# Created by GNU Automake missing as a replacement of" + echo "# $ $@" + echo "exit 0" + chmod +x $file + exit 1 + fi + ;; + + bison|yacc) + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified a \`.y' file. You may need the \`Bison' package + in order for those modifications to take effect. You can get + \`Bison' from any GNU archive site." + rm -f y.tab.c y.tab.h + if [ $# -ne 1 ]; then + eval LASTARG="\${$#}" + case "$LASTARG" in + *.y) + SRCFILE=`echo "$LASTARG" | sed 's/y$/c/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" y.tab.c + fi + SRCFILE=`echo "$LASTARG" | sed 's/y$/h/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" y.tab.h + fi + ;; + esac + fi + if [ ! -f y.tab.h ]; then + echo >y.tab.h + fi + if [ ! -f y.tab.c ]; then + echo 'main() { return 0; }' >y.tab.c + fi + ;; + + lex|flex) + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified a \`.l' file. You may need the \`Flex' package + in order for those modifications to take effect. You can get + \`Flex' from any GNU archive site." + rm -f lex.yy.c + if [ $# -ne 1 ]; then + eval LASTARG="\${$#}" + case "$LASTARG" in + *.l) + SRCFILE=`echo "$LASTARG" | sed 's/l$/c/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" lex.yy.c + fi + ;; + esac + fi + if [ ! -f lex.yy.c ]; then + echo 'main() { return 0; }' >lex.yy.c + fi + ;; + + help2man) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified a dependency of a manual page. You may need the + \`Help2man' package in order for those modifications to take + effect. You can get \`Help2man' from any GNU archive site." + + file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'` + if test -z "$file"; then + file=`echo "$*" | sed -n 's/.*--output=\([^ ]*\).*/\1/p'` + fi + if [ -f "$file" ]; then + touch $file + else + test -z "$file" || exec >$file + echo ".ab help2man is required to generate this page" + exit 1 + fi + ;; + + makeinfo) + if test -z "$run" && (makeinfo --version) > /dev/null 2>&1; then + # We have makeinfo, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is missing on your system. You should only need it if + you modified a \`.texi' or \`.texinfo' file, or any other file + indirectly affecting the aspect of the manual. The spurious + call might also be the consequence of using a buggy \`make' (AIX, + DU, IRIX). You might want to install the \`Texinfo' package or + the \`GNU make' package. Grab either from any GNU archive site." + file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'` + if test -z "$file"; then + file=`echo "$*" | sed 's/.* \([^ ]*\) *$/\1/'` + file=`sed -n '/^@setfilename/ { s/.* \([^ ]*\) *$/\1/; p; q; }' $file` + fi + touch $file + ;; + + tar) + shift + if test -n "$run"; then + echo 1>&2 "ERROR: \`tar' requires --run" + exit 1 + fi + + # We have already tried tar in the generic part. + # Look for gnutar/gtar before invocation to avoid ugly error + # messages. + if (gnutar --version > /dev/null 2>&1); then + gnutar "$@" && exit 0 + fi + if (gtar --version > /dev/null 2>&1); then + gtar "$@" && exit 0 + fi + firstarg="$1" + if shift; then + case "$firstarg" in + *o*) + firstarg=`echo "$firstarg" | sed s/o//` + tar "$firstarg" "$@" && exit 0 + ;; + esac + case "$firstarg" in + *h*) + firstarg=`echo "$firstarg" | sed s/h//` + tar "$firstarg" "$@" && exit 0 + ;; + esac + fi + + echo 1>&2 "\ +WARNING: I can't seem to be able to run \`tar' with the given arguments. + You may want to install GNU tar or Free paxutils, or check the + command line arguments." + exit 1 + ;; + + *) + echo 1>&2 "\ +WARNING: \`$1' is needed, and you do not seem to have it handy on your + system. You might have modified some files without having the + proper tools for further handling them. Check the \`README' file, + it often tells you about the needed prerequirements for installing + this package. You may also peek at any GNU archive site, in case + some other package would contain this missing \`$1' program." + exit 1 + ;; +esac + +exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/mkinstalldirs b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/mkinstalldirs new file mode 100755 index 00000000..8ab885ec --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/mkinstalldirs @@ -0,0 +1,99 @@ +#! /bin/sh +# mkinstalldirs --- make directory hierarchy +# Author: Noah Friedman +# Created: 1993-05-16 +# Public domain + +errstatus=0 +dirmode="" + +usage="\ +Usage: mkinstalldirs [-h] [--help] [-m mode] dir ..." + +# process command line arguments +while test $# -gt 0 ; do + case "${1}" in + -h | --help | --h* ) # -h for help + echo "${usage}" 1>&2; exit 0 ;; + -m ) # -m PERM arg + shift + test $# -eq 0 && { echo "${usage}" 1>&2; exit 1; } + dirmode="${1}" + shift ;; + -- ) shift; break ;; # stop option processing + -* ) echo "${usage}" 1>&2; exit 1 ;; # unknown option + * ) break ;; # first non-opt arg + esac +done + +for file +do + if test -d "$file"; then + shift + else + break + fi +done + +case $# in +0) exit 0 ;; +esac + +case $dirmode in +'') + if mkdir -p -- . 2>/dev/null; then + echo "mkdir -p -- $*" + exec mkdir -p -- "$@" + fi ;; +*) + if mkdir -m "$dirmode" -p -- . 2>/dev/null; then + echo "mkdir -m $dirmode -p -- $*" + exec mkdir -m "$dirmode" -p -- "$@" + fi ;; +esac + +for file +do + set fnord `echo ":$file" | sed -ne 's/^:\//#/;s/^://;s/\// /g;s/^#/\//;p'` + shift + + pathcomp= + for d + do + pathcomp="$pathcomp$d" + case "$pathcomp" in + -* ) pathcomp=./$pathcomp ;; + esac + + if test ! -d "$pathcomp"; then + echo "mkdir $pathcomp" + + mkdir "$pathcomp" || lasterr=$? + + if test ! -d "$pathcomp"; then + errstatus=$lasterr + else + if test ! -z "$dirmode"; then + echo "chmod $dirmode $pathcomp" + + lasterr="" + chmod "$dirmode" "$pathcomp" || lasterr=$? + + if test ! -z "$lasterr"; then + errstatus=$lasterr + fi + fi + fi + fi + + pathcomp="$pathcomp/" + done +done + +exit $errstatus + +# Local Variables: +# mode: shell-script +# sh-indentation: 3 +# End: +# mkinstalldirs ends here diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/Arguments.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/Arguments.Po new file mode 100755 index 00000000..241807a6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/Arguments.Po @@ -0,0 +1,402 @@ +Arguments.o Arguments.o: Arguments.cpp Arguments.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/include/bits/stdio_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/types.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/time.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/libio.h /usr/include/_G_config.h \ + /usr/include/wchar.h /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/sys_errlist.h /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/signal.h \ + /usr/include/bits/initspin.h /usr/include/bits/sigthread.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/environments.h /usr/include/bits/confname.h \ + /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype \ + /usr/include/wctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits \ + 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+/usr/include/bits/local_lim.h: + +/usr/include/linux/limits.h: + +/usr/include/bits/posix2_lim.h: + +/usr/include/bits/xopen_lim.h: + +/usr/include/bits/stdio_lim.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib: + +/usr/include/stdlib.h: + +/usr/include/bits/waitflags.h: + +/usr/include/bits/waitstatus.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/types.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/time.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception: + 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+/usr/include/stdint.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert: + +/usr/include/assert.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h: + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype: + +/usr/include/wctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/glib.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/glib.Po new file mode 100755 index 00000000..f2e2333e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/glib.Po @@ -0,0 +1,90 @@ +glib.o glib.o: glib.c graphtypes.h /usr/include/stdlib.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/sys/types.h /usr/include/bits/types.h \ + /usr/include/bits/wordsize.h /usr/include/bits/typesizes.h \ + /usr/include/time.h /usr/include/endian.h /usr/include/bits/endian.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h /usr/include/stdio.h \ + /usr/include/libio.h /usr/include/_G_config.h /usr/include/wchar.h \ + /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h + +graphtypes.h: + +/usr/include/stdlib.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/sys/types.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/stdio.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/main.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/main.Po new file mode 100755 index 00000000..cf423a12 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/main.Po @@ -0,0 +1,518 @@ +main.o main.o: main.cpp \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/deque \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + 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+/usr/include/sys/times.h: + +../config.h: + +Arguments.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +alignment.h: + +types.h: + +algebra.h: + +ppforest.h: + +misc.h: + +ppforestbase.h: + +ppforestali.h: + +debug.h: + +treeedit.h: + +ppforestsz.h: + +progressive_align.h: + +graphtypes.h: + +matrix.h: + +rnaforester_options.h: + +rna_profile_alignment.h: + +rna_algebra.h: + +rna_alphabet.h: + +wmatch.h: + +rna_alignment.h: + +rnaforest.h: + +rnafuncs.h: + +alignment.t.cpp: + +misc.t.cpp: + +ppforest.t.cpp: + +rnaforestsz.h: + +treeedit.t.cpp: + +ppforestsz.t.cpp: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/ppforestbase.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/ppforestbase.Po new file mode 100755 index 00000000..ab91b357 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/ppforestbase.Po @@ -0,0 +1,398 @@ +ppforestbase.o ppforestbase.o: ppforestbase.cpp misc.h types.h \ + ppforestbase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +misc.t.cpp: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/progressive_align.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/progressive_align.Po new file mode 100755 index 00000000..0f715168 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/progressive_align.Po @@ -0,0 +1,494 @@ +progressive_align.o progressive_align.o: progressive_align.cpp \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: + +rna_profile_alignment.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/deque: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_deque.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/deque.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cpp_type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h: + +rna_algebra.h: + +debug.h: + +rna_alphabet.h: + +wmatch.h: + +alignment.t.cpp: + +misc.t.cpp: + +ppforest.t.cpp: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_algebra.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_algebra.Po new file mode 100755 index 00000000..ff7581bd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_algebra.Po @@ -0,0 +1,423 @@ +rna_algebra.o rna_algebra.o: rna_algebra.cpp rna_algebra.h \ + /usr/include/assert.h /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +misc.h: + +types.h: + +rna_alphabet.h: + +rnaforester_options.h: + +../config.h: + +Arguments.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alignment.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alignment.Po new file mode 100755 index 00000000..50ba94b2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alignment.Po @@ -0,0 +1,473 @@ +rna_alignment.o rna_alignment.o: rna_alignment.cpp \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/include/bits/stdio_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/types.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/time.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/libio.h /usr/include/_G_config.h \ + /usr/include/wchar.h /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/sys_errlist.h /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/signal.h \ + /usr/include/bits/initspin.h /usr/include/bits/sigthread.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/environments.h /usr/include/bits/confname.h \ + /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc \ + ../config.h misc.h types.h rna_alignment.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype \ + /usr/include/wctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cpp_type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h \ + alignment.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc \ + algebra.h ppforest.h ppforestbase.h ppforestali.h rna_algebra.h debug.h \ + rna_alphabet.h rnaforester_options.h Arguments.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc \ + rnaforest.h rnafuncs.h alignment.t.cpp misc.t.cpp ppforest.t.cpp \ + utils.h + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/string.h: + +/usr/include/xlocale.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h: + +/usr/include/limits.h: + +/usr/include/bits/posix1_lim.h: + +/usr/include/bits/local_lim.h: + +/usr/include/linux/limits.h: + +/usr/include/bits/posix2_lim.h: + +/usr/include/bits/xopen_lim.h: + +/usr/include/bits/stdio_lim.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib: + +/usr/include/stdlib.h: + +/usr/include/bits/waitflags.h: + +/usr/include/bits/waitstatus.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/types.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/time.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio: + +/usr/include/stdio.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale: + +/usr/include/locale.h: + +/usr/include/bits/locale.h: + +/usr/include/langinfo.h: + +/usr/include/nl_types.h: + +/usr/include/iconv.h: + +/usr/include/libintl.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h: + +/usr/include/pthread.h: + +/usr/include/sched.h: + +/usr/include/signal.h: + +/usr/include/bits/initspin.h: + +/usr/include/bits/sigthread.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/environments.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype: + +/usr/include/ctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime: + +/usr/include/stdint.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert: + +/usr/include/assert.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc: + +../config.h: + +misc.h: + +types.h: + +rna_alignment.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype: + +/usr/include/wctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cpp_type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h: + +alignment.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc: + +algebra.h: + +ppforest.h: + +ppforestbase.h: + +ppforestali.h: + +rna_algebra.h: + +debug.h: + +rna_alphabet.h: + +rnaforester_options.h: + +Arguments.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: + +rnaforest.h: + +rnafuncs.h: + +alignment.t.cpp: + +misc.t.cpp: + +ppforest.t.cpp: + +utils.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alphabet.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alphabet.Po new file mode 100755 index 00000000..c33fe72a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_alphabet.Po @@ -0,0 +1,306 @@ +rna_alphabet.o rna_alphabet.o: rna_alphabet.cpp rna_alphabet.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/include/bits/stdio_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/types.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/time.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/libio.h /usr/include/_G_config.h \ + /usr/include/wchar.h /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/sys_errlist.h /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/signal.h \ + /usr/include/bits/initspin.h /usr/include/bits/sigthread.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/environments.h /usr/include/bits/confname.h \ + /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc + +rna_alphabet.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef: + 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+/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale: + +/usr/include/locale.h: + +/usr/include/bits/locale.h: + +/usr/include/langinfo.h: + +/usr/include/nl_types.h: + +/usr/include/iconv.h: + +/usr/include/libintl.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h: + +/usr/include/pthread.h: + +/usr/include/sched.h: + +/usr/include/signal.h: + +/usr/include/bits/initspin.h: + +/usr/include/bits/sigthread.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/environments.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype: + +/usr/include/ctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime: + +/usr/include/stdint.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert: + +/usr/include/assert.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_profile_alignment.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_profile_alignment.Po new file mode 100755 index 00000000..bb199f02 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rna_profile_alignment.Po @@ -0,0 +1,524 @@ +rna_profile_alignment.o rna_profile_alignment.o: \ + rna_profile_alignment.cpp ../config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cmath \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cpp_type_traits.h \ + /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/nan.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cmath.tcc \ + ../g2-0.70/include/g2.h ../g2-0.70/include/g2_PS.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/fstream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/bits/types.h \ + /usr/include/bits/wordsize.h /usr/include/bits/typesizes.h \ + /usr/include/libio.h /usr/include/_G_config.h /usr/include/wchar.h \ + /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/time.h \ + /usr/include/bits/sched.h /usr/include/bits/time.h \ + /usr/include/signal.h /usr/include/bits/sigset.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/initspin.h \ + /usr/include/bits/sigthread.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/environments.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h /usr/include/endian.h /usr/include/bits/endian.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/sys/types.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/sys/sysmacros.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype \ + /usr/include/wctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/basic_file.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/fstream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iomanip \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/functional \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc \ + matrix.h rna_profile_alignment.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/deque \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_deque.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/deque.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h \ + alignment.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc \ + types.h algebra.h ppforest.h misc.h ppforestbase.h ppforestali.h \ + rna_algebra.h debug.h rna_alphabet.h rnaforester_options.h Arguments.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc \ + rnafuncs.h utils.h part_func.h fold_vars.h fold.h ppforest.t.cpp + +../config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cmath: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h: + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/functional: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: + +matrix.h: + +rna_profile_alignment.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/deque: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_deque.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/deque.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h: + +alignment.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc: + +types.h: + +algebra.h: + +ppforest.h: + +misc.h: + +ppforestbase.h: + +ppforestali.h: + +rna_algebra.h: + +debug.h: + +rna_alphabet.h: + +rnaforester_options.h: + +Arguments.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +rnafuncs.h: + +utils.h: + +part_func.h: + +fold_vars.h: + +fold.h: + +ppforest.t.cpp: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforest.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforest.Po new file mode 100755 index 00000000..0abc2b50 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforest.Po @@ -0,0 +1,416 @@ +rnaforest.o rnaforest.o: rnaforest.cpp ../config.h rnaforest.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype: + +/usr/include/wctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +algebra.h: + +ppforest.h: + +misc.h: + +types.h: + +ppforestbase.h: + +rna_alphabet.h: + +rnafuncs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc: + +ppforest.t.cpp: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforester_options.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforester_options.Po new file mode 100755 index 00000000..0353cc8b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforester_options.Po @@ -0,0 +1,412 @@ +rnaforester_options.o rnaforester_options.o: rnaforester_options.cpp \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/bits/types.h \ + /usr/include/bits/wordsize.h /usr/include/bits/typesizes.h \ + /usr/include/libio.h /usr/include/_G_config.h /usr/include/wchar.h \ + /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/time.h \ + /usr/include/bits/sched.h /usr/include/bits/time.h \ + /usr/include/signal.h /usr/include/bits/sigset.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/initspin.h \ + /usr/include/bits/sigthread.h /usr/include/unistd.h \ + /usr/include/bits/posix_opt.h /usr/include/bits/environments.h \ + /usr/include/bits/confname.h /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h /usr/include/endian.h /usr/include/bits/endian.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/sys/types.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/sys/sysmacros.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype \ + /usr/include/wctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc \ + ../config.h rnaforester_options.h Arguments.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc \ + types.h + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios: + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale: + +/usr/include/locale.h: + +/usr/include/bits/locale.h: + +/usr/include/langinfo.h: + +/usr/include/nl_types.h: + +/usr/include/iconv.h: + +/usr/include/libintl.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h: + +/usr/include/pthread.h: + +/usr/include/sched.h: + +/usr/include/time.h: + +/usr/include/bits/sched.h: + +/usr/include/bits/time.h: + +/usr/include/signal.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/initspin.h: + +/usr/include/bits/sigthread.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/environments.h: + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/sstream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/sstream.tcc: + +../config.h: + +rnaforester_options.h: + +Arguments.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/vector: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_vector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_bvector.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/vector.tcc: + +types.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforestsz.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforestsz.Po new file mode 100755 index 00000000..a57ef48d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnaforestsz.Po @@ -0,0 +1,424 @@ +rnaforestsz.o rnaforestsz.o: rnaforestsz.cpp rnaforestsz.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype: + +/usr/include/wctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +ppforestsz.h: + +misc.h: + +types.h: + +rna_alphabet.h: + +rnafuncs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc: + +ppforestsz.t.cpp: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/map: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tree.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/cpp_type_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_map.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_multimap.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnafuncs.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnafuncs.Po new file mode 100755 index 00000000..5e1fb1b8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/rnafuncs.Po @@ -0,0 +1,421 @@ +rnafuncs.o rnafuncs.o: rnafuncs.cpp \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/string.h /usr/include/xlocale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h \ + /usr/include/limits.h /usr/include/bits/posix1_lim.h \ + /usr/include/bits/local_lim.h /usr/include/linux/limits.h \ + /usr/include/bits/posix2_lim.h /usr/include/bits/xopen_lim.h \ + /usr/include/bits/stdio_lim.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib \ + /usr/include/stdlib.h /usr/include/bits/waitflags.h \ + /usr/include/bits/waitstatus.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/types.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/time.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio \ + /usr/include/stdio.h /usr/include/libio.h /usr/include/_G_config.h \ + /usr/include/wchar.h /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/sys_errlist.h /usr/include/bits/stdio.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale \ + /usr/include/locale.h /usr/include/bits/locale.h \ + /usr/include/langinfo.h /usr/include/nl_types.h /usr/include/iconv.h \ + /usr/include/libintl.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h \ + /usr/include/pthread.h /usr/include/sched.h /usr/include/signal.h \ + /usr/include/bits/initspin.h /usr/include/bits/sigthread.h \ + /usr/include/unistd.h /usr/include/bits/posix_opt.h \ + /usr/include/bits/environments.h /usr/include/bits/confname.h \ + /usr/include/getopt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype \ + /usr/include/ctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime \ + /usr/include/stdint.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_pair.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/type_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_types.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator_base_funcs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/concept_check.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/debug/debug.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cassert \ + /usr/include/assert.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_construct.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_uninitialized.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algo.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_heap.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_tempbuf.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/memory \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ext/new_allocator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_raw_storage_iter.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iomanip \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/istream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype \ + /usr/include/wctype.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/functional \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream \ + debug.h misc.h types.h rnafuncs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc \ + utils.h ../config.h ../g2-0.70/include/g2.h ../g2-0.70/include/g2_PS.h \ + ../g2-0.70/include/g2_FIG.h + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/algorithm: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_algobase.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++config.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/os_defines.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstring: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstddef: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/string.h: + +/usr/include/xlocale.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/climits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/limits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/syslimits.h: + +/usr/include/limits.h: + +/usr/include/bits/posix1_lim.h: + +/usr/include/bits/local_lim.h: + +/usr/include/linux/limits.h: + +/usr/include/bits/posix2_lim.h: + +/usr/include/bits/xopen_lim.h: + +/usr/include/bits/stdio_lim.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdlib: + +/usr/include/stdlib.h: + +/usr/include/bits/waitflags.h: + +/usr/include/bits/waitstatus.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/types.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/time.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/new: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iosfwd: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++locale.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cstdio: + +/usr/include/stdio.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/clocale: + +/usr/include/locale.h: + +/usr/include/bits/locale.h: + +/usr/include/langinfo.h: + +/usr/include/nl_types.h: + +/usr/include/iconv.h: + +/usr/include/libintl.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/c++io.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/gthr-default.h: + +/usr/include/pthread.h: + +/usr/include/sched.h: + +/usr/include/signal.h: + +/usr/include/bits/initspin.h: + +/usr/include/bits/sigthread.h: + +/usr/include/unistd.h: + +/usr/include/bits/posix_opt.h: + +/usr/include/bits/environments.h: + +/usr/include/bits/confname.h: + +/usr/include/getopt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cctype: + +/usr/include/ctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stringfwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/postypes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwchar: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ctime: + +/usr/include/stdint.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/functexcept.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/exception_defines.h: + 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+/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ios: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/char_traits.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/localefwd.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ios_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/atomicity.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/atomic_word.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_classes.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/string: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_function.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_string.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/streambuf: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/streambuf_iterator.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/cwctype: + +/usr/include/wctype.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_base.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/ctype_inline.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/codecvt.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/codecvt_specializations.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/time_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/i686-pc-linux-gnu/bits/messages_members.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/basic_ios.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/limits: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/istream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/locale: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/locale_facets.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/typeinfo: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/ostream: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/ostream.tcc: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/functional: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/iostream: + +debug.h: + +misc.h: + +types.h: + +rnafuncs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/list: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/stl_list.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/../../../../include/c++/3.4.1/bits/list.tcc: + +utils.h: + +../config.h: + +../g2-0.70/include/g2.h: + +../g2-0.70/include/g2_PS.h: + +../g2-0.70/include/g2_FIG.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/wmatch.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/wmatch.Po new file mode 100755 index 00000000..6537804d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/.deps/wmatch.Po @@ -0,0 +1,92 @@ +wmatch.o wmatch.o: wmatch.c match.defs graphtypes.h wmatch.h pairs.c \ + pointer.c readgraph.c /usr/include/stdlib.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/sys/types.h /usr/include/bits/types.h \ + /usr/include/bits/wordsize.h /usr/include/bits/typesizes.h \ + /usr/include/time.h /usr/include/endian.h /usr/include/bits/endian.h \ + /usr/include/sys/select.h /usr/include/bits/select.h \ + /usr/include/bits/sigset.h /usr/include/bits/time.h \ + /usr/include/sys/sysmacros.h /usr/include/bits/pthreadtypes.h \ + /usr/include/bits/sched.h /usr/include/alloca.h /usr/include/stdio.h \ + /usr/include/libio.h /usr/include/_G_config.h /usr/include/wchar.h \ + /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h term.c unpairs.c + +match.defs: + +graphtypes.h: + +wmatch.h: + +pairs.c: + +pointer.c: + +readgraph.c: + +/usr/include/stdlib.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/sys/types.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/stdio.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +term.c: + +unpairs.c: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.cpp new file mode 100755 index 00000000..eae31f21 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.cpp @@ -0,0 +1,221 @@ +/* + * Arguments 2.0 Beta - A Command Line Processing Library + * Copyright (C) 2000, 2001 Jared Davis + * + * This program is free software; you can redistribute it and/or modify it + * under the terms of the GNU General Public License as published by the + * Free Software Foundation; either version 2 of the License, or (at your + * option) any later version. + * + * This program is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY + * or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License + * for more details. + * + * You should have received a copy of the GNU General Public License along + * with this program; if not, write to the Free Software Foundation, Inc., + * 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA. + */ + +#include "Arguments.h" +#include + +std::vector Arguments::s_spaceArgs; + +// +// ExplodeString function +// ---------------------- +// Explodes a string into tokens, which it adds to a vector. +// (This function is taken from the AFA library, also by Jared Davis) +// +void Arguments::ExplodeString(const std::string& str, std::vector& tokens, char delimiter) +throw(std::bad_alloc) +{ + string::size_type next, prev = 0; + + do + { + next = str.find(delimiter, prev); + + tokens.push_back( str.substr(prev, next - prev) ); + + prev = next + 1; + + } while(next != string::npos); +} + +// +// findArgument +// ------------ +// Performs a binary search on the argument vector and returns the integer +// corresponding to the argument, if it exists. Otherwise returns -1. +// arg is a pipe-delimited list of acceptable arguments. +// +int Arguments::findArgument(const string& arg) const throw() +{ + if (d_arguments.size() == 0) + { + return -1; + } + + vector tokens; + ExplodeString(arg, tokens, '|'); + + for(unsigned int i = 0;i < tokens.size();++i) + { + int low = 0; + int high = d_arguments.size() - 1; + + while(low <= high) + { + unsigned int mid = (low + high) / 2; + + if (tokens[i] < d_arguments[mid].first) + { + high = mid - 1; + } + + else if (tokens[i] > d_arguments[mid].first) + { + low = mid + 1; + } + + else + { + return mid; + } + } + } + + return -1; +} + + +// +// Arguments::setArgumentsWithSpaces +// --------------------------------- +// Adds all tokens of the pipe-delimited string, args, to the +// spaces vector. keeps the vector sorted. +// +void Arguments::setArgumentsWithSpaces(const string& args) +throw(std::bad_alloc) +{ + ExplodeString(args, s_spaceArgs, '|'); + std::sort(s_spaceArgs.begin(), s_spaceArgs.end()); +} + + +Arguments::Arguments(int argc, const char** argv) throw(std::bad_alloc) +{ + // start at 1 to skip program's name. + for(int i = 1;i < argc;++i) + { + // Extract this token. + string this_arg = argv[i]; + + // Try to find a colon or an equals sign. + string::size_type colon = this_arg.find(':'); + if (colon == string::npos) + { + colon = this_arg.find('='); + } + + // Add arg/val pair if we have a colon or equals sign. + if (colon != string::npos) + { + d_arguments.push_back(make_pair( + this_arg.substr(0, colon), + make_pair(this_arg.substr(colon + 1), true) + )); + + continue; + } + + // If we get here, we didn't find a colon or an equals, we need to + // consult the spaces list. + if (i < (argc - 1)) + { + if (std::binary_search(s_spaceArgs.begin(), s_spaceArgs.end(), this_arg)) + { + // if parameter value starts with "-" consider it as an option + if(argv[i+1][0]=='-') + { + d_arguments.push_back(make_pair( + this_arg, + make_pair(string(""), false))); + continue; // i is not incrented !! + } + else + { + d_arguments.push_back(make_pair( + this_arg, + make_pair(argv[++i], true) + )); + continue; + } + } + } + + // If we get here, we either don't have a space, or we are at the last + // argument that we were passed, so we can't possibly have a value for + // this argument. Throw it into the map with an empty value. + d_arguments.push_back(make_pair( + this_arg, + make_pair(string(""), false) + )); + } + + // Now let's sort the argument list so it's fast to find them. + std::sort(d_arguments.begin(), d_arguments.end()); +} + + +// +// Arguments::size +// --------------- +// Returns the number of command-line arguments that your program was passed. +// This is not the same as argc: it does not include your program's name, nor +// does it include the values passed to your command-line arguments. +// +unsigned int Arguments::size() const throw() +{ + return d_arguments.size(); +} + + +// +// Arguments::has +// -------------- +// Cycle through the tokens of argument and return true if any of them +// are found. +// +bool Arguments::has(const std::string& argument) const throw(std::bad_alloc) +{ + return findArgument(argument) != -1; +} + + + + +/* +#ifndef NDEBUG + + #include + + void Arguments::debug() const + { + cout << "Arguments Debug Information-----\n" << endl; + cout << "Number of space-taking arguments: " << s_spaceArgs.size() << "\n\t"; + copy(s_spaceArgs.begin(), s_spaceArgs.end(), ostream_iterator(cout, "\n\t")); + + cout << "Arguments Map: " << size() << " Elements. " << endl; + for(unsigned int i = 0;i < size();++i) + { + cout << "\t" << d_arguments[i].first << " = " << d_arguments[i].second.first << " (" + << d_arguments[i].second.second << ")\n"; + } + cout << "\n-----End of Arguments Debug Information" << endl; + } + +#endif +*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.h new file mode 100755 index 00000000..b5f025ae --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.h @@ -0,0 +1,110 @@ +/* + * Arguments 2.0 Beta - A Command Line Processing Library + * Copyright (C) 2000, 2001 Jared Davis + * + * This program is free software; you can redistribute it and/or modify it + * under the terms of the GNU General Public License as published by the + * Free Software Foundation; either version 2 of the License, or (at your + * option) any later version. + * + * This program is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY + * or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License + * for more details. + * + * You should have received a copy of the GNU General Public License along + * with this program; if not, write to the Free Software Foundation, Inc., + * 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA. + */ + +#ifndef INCLUDED_OPENDELI_ARGUMENTS_H +#define INCLUDED_OPENDELI_ARGUMENTS_H + +#if (defined(_WIN32) && defined(_DEBUG)) +// In visual studio, compiling this library gives you a billion and a half +// error messages that "debug information has been truncated to 255 chars" +// because the visual studio debugger can't handle symbols longer than 255 +// characters. This disables this warning so we comile cleanly. + #pragma warning( disable: 4786 ) +#endif + +#include +#include +#include + +using namespace std; + +class Arguments +{ + private: + + // Vector of the arguments that take spaces. + static std::vector s_spaceArgs; + + // Vector of argument-value pairs. + std::vector< std::pair > > d_arguments; + + + // explodes a delimited string into its tokens. + static void ExplodeString(const std::string& str, std::vector& tokens, char delimiter) + throw(std::bad_alloc); + + // finds the index of the argument arg. + int findArgument(const std::string& arg) const throw(); + + // + // convert(source, target) + // Converts a variable of type A into a variable of type B by passing + // it through a strstream. + // + template + static bool convert(const A& source, B& target) throw() + { + std::stringstream ss; + ss.clear(); + ss << source; + ss >> target; + return (!ss.bad() && !ss.fail()); + } + + + public: + + static void setArgumentsWithSpaces(const std::string& args) + throw(std::bad_alloc); + + Arguments(int argc, const char** argv) + throw(std::bad_alloc); + + unsigned int size() const throw(); + + bool has(const std::string& arg) const throw(std::bad_alloc); + + template bool get + (const std::string& arg, A& value, const B& default_value) const + throw(std::bad_alloc) + { + int index = findArgument(arg); + + if (index == -1) { + value = default_value; + return false; + } + + else + { + bool ret = convert(d_arguments[index].second.first, value); + if (!ret) + value = default_value; + return ret; + } + } + + + #ifndef NDEBUG + void debug() const; + #endif + +}; + +#endif // INCLUDED_OPENDELI_ARGUMENTS_H diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/Arguments.o new file mode 100755 index 0000000000000000000000000000000000000000..15221440fca714a0676a529873882a1ea2171802 GIT binary patch literal 253312 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/**< Result for the empty tree alignment */ + virtual R replace(L a,R down, L b, R over) const =0; /**< Result for the tree edit function 'replace' */ + virtual R del(L a,R down, R over) const =0; /**< Result for the tree edit function 'delete' */ + virtual R insert(R down,L b,R over) const =0; /**< Result for the tree edit function 'insert' */ + virtual R choice(R a,R b) const =0; /**< The choice function. Commonly used functions are 'min' and 'max' */ + virtual R worst_score() const =0; /**< The worst_score with respect to choice is specified by this function */ + + virtual ~Algebra() {}; +}; + +/** Extended Algebra for aligning RNA secondary structure trees where basepair replacements + * are considered as a single edit operation. + */ +template +class RNA_Algebra : public Algebra +{ +public: + /** Result for the replacement of a basepair */ + virtual R replacepair(L la, L lb, R down, L ra, L rb, R over) const =0; +}; + +/** Algebra for the tree edit model */ +template +class SZAlgebra +{ +public: + virtual R empty() const =0; /**< Result for the empty tree alignment */ + virtual R replace(L a,R down, L b) const =0; /**< Result for the tree edit function 'replace' */ + virtual R del(L a,R down) const =0; /**< Result for the tree edit function 'delete' */ + virtual R insert(R down,L b) const =0; /**< Result for the tree edit function 'insert' */ + virtual R choice(R a,R b) const =0; /**< The choice function. Commonly used functions are 'min' and 'max' */ + virtual R worst_score() const =0; /**< The worst_score with respect to choice is specified by this function */ + + virtual ~SZAlgebra() {}; +}; + +#endif + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.h new file mode 100755 index 00000000..8a44919d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.h @@ -0,0 +1,93 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _ALIGNMENT_H_ +#define _ALIGNMENT_H_ + +#include +#include + +#include "types.h" +#include "algebra.h" +#include "ppforest.h" +#include "ppforestali.h" + +template +class Alignment +{ +private: + struct CSFPair + { + Uint i; + Uint j; + Uint k; + Uint l; + + CSFPair(Uint i, Uint j, Uint k, Uint l) : i(i),j(j),k(k),l(l) {}; + }; + + R *m_mtrx; + Ulong *m_rowStart; + Ulong m_mtrxSize; + + PPForest *m_ppfx; + PPForest *m_ppfy; + + const Algebra *m_alg; + const RNA_Algebra *m_rnaAlg; + + R m_localOptimum; + R m_localSubOptimum; + std::list m_localAlis; // holds which alignments are already produced by getOptLocalAlignment + double m_suboptimalsPercent; // percentage is stores as a value between 0 and 1 + + inline R getMtrxVal(Ulong i,Ulong j) const + { + assert(m_rowStart[i]+jchoice(m_localOptimum,val); // here we calculate local similarity on the fly + }; + + void calculateLocal(const PPForest *ppfx, const PPForest *ppfy,const Algebra &alg, bool noSpeedup=false); + void calculateGlobal(const PPForest *ppfx, const PPForest *ppfy,const Algebra &alg, bool noSpeedup=false); + Uint backtrack(PPForestAli &ppf,Uint i, Uint j, Uint k, Uint l, Uint &node); +public: + Alignment(const PPForest *ppfx, const PPForest *ppfy,const Algebra &alg, bool local, bool noSpeedup=false); + Alignment(const PPForest *ppfx, const PPForest *ppfy,const RNA_Algebra &rnaAlg); + ~Alignment(); + + R getGlobalOptimum(); + + /** This function should only be used in conjunction with + * similarity based algebras + */ + double getGlobalOptimumRelative(); + + inline R getLocalOptimum(){return m_localSubOptimum;}; + R getSILOptimum(); + void getOptGlobalAlignment(PPForestAli &ppfali); + + void resetOptLocalAlignment(int suboptimalsPercent=100); + bool nextLocalSuboptimum(); + void getOptLocalAlignment(PPForestAli &ppfali,Uint &xbasepos, Uint &ybasepos); + void getOptSILAlignment(PPForestAli &ppfali,Uint &ybasepos); +}; + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.t.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.t.cpp new file mode 100755 index 00000000..178f3aa2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/alignment.t.cpp @@ -0,0 +1,1004 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _ALIGNMENT_T_CPP_ +#define _ALIGNMENT_T_CPP_ + +#include +#include + +#include "alignment.h" +#include "debug.h" + +#include "misc.t.cpp" +#include "ppforest.t.cpp" + +/* ****************************************** */ +/* Constructor and Destruktor functions */ +/* ****************************************** */ + +template +Alignment::Alignment(const PPForest *ppfx, const PPForest *ppfy, const Algebra &alg, bool local, bool noSpeedup) +: m_suboptimalsPercent(100) +{ + if(local) + calculateLocal(ppfx,ppfy,alg,noSpeedup); + else + calculateGlobal(ppfx,ppfy,alg,noSpeedup); +} + +template +Alignment::Alignment(const PPForest *ppfx, const PPForest *ppfy, const RNA_Algebra &rnaAlg) +: m_suboptimalsPercent(100) +{ + assert(ppfx != NULL); + assert(ppfy != NULL); + + Ulong m,n,h,cols; + long i,k; + Uint j,l,r; + + R score,h_score; + + // alloc space for the score matrix, backtrack structure and , if wanted, for the calculation-order-matrix + m_mtrxSize=ppfx->getNumCSFs()*ppfy->getNumCSFs(); + + m_mtrx=new R[m_mtrxSize]; + m_rowStart=new Ulong[ppfx->getNumCSFs()]; + m_ppfx = new PPForest(*ppfx); // copy the ppforests + m_ppfy = new PPForest(*ppfy); + m_rnaAlg=&rnaAlg; + m_alg=(const Algebra*)&rnaAlg; + m_localOptimum=rnaAlg.worst_score(); + + // initialize variables + m=ppfx->size(); + n=ppfy->size(); + cols=ppfy->getNumCSFs(); + + m_rowStart[0]=0; + for(h=1;hgetNumCSFs();h++) + m_rowStart[h]=m_rowStart[h-1]+cols; + + // align forests fx and fy + + // the easiest case .. + setMtrxVal(0,0,rnaAlg.empty()); + + // align fx to the empty forest (fill first row of array) + for(i=m-1;i>=0;i--) // for all nodes in fx + { + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + { + score = rnaAlg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),0), + getMtrxVal(ppfx->over(i,j),0)); + + setMtrxVal(ppfx->indexpos(i,j),0,score); + } + } + + // align fy to the empty forest (fill first column of array) + for(k=n-1;k>=0;k--) // for all nodes in fx + { + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + score = rnaAlg.insert(getMtrxVal(0,ppfy->down(k)), + ppfy->label(k), + getMtrxVal(0,ppfy->over(k,l))); + + setMtrxVal(0,ppfy->indexpos(k,l),score); + } + } + + // align the rest + for(i=m-1;i>=0;i--) // for all nodes in fx + for(k=n-1;k>=0;k--) // for all nodes in fx + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + // basepair replacement + if(ppfx->down(i) && ppfy->down(k)) + { + // must be two P nodes !! + h_score = rnaAlg.replacepair(ppfx->label(i+1), + ppfy->label(k+1), + getMtrxVal(ppfx->mdown(i),ppfy->mdown(k)), + ppfx->label(ppfx->getRightmostBrotherIndex(i+1)), + ppfy->label(ppfy->getRightmostBrotherIndex(k+1)), + getMtrxVal(ppfx->over(i,j),ppfy->over(k,l))); + } + else + { + h_score = rnaAlg.replace(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->over(i,j),ppfy->over(k,l))); + } + + score=h_score; + + // delete + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = rnaAlg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,r)), + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(h,l-r))); + + score=rnaAlg.choice(score,h_score); + h=ppfy->rb(h); + } + + // insert + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = rnaAlg.insert(getMtrxVal(ppfx->indexpos(i,r),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->indexpos(h,j-r),ppfy->over(k,l))); + + score=rnaAlg.choice(score,h_score); + h=ppfx->rb(h); + } + + // set value + setMtrxVal(ppfx->indexpos(i,j),ppfy->indexpos(k,l),score); + } + + // showArray(m_mtrx,ppfx->getNumCSFs(),ppfy->getNumCSFs()); + resetOptLocalAlignment(100); +} + + + +template +Alignment::~Alignment() +{ + delete[] m_mtrx; + delete[] m_rowStart; + delete m_ppfx; + delete m_ppfy; +} + + + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +template +void Alignment::calculateLocal(const PPForest *ppfx, const PPForest *ppfy, const Algebra &alg, bool noSpeedup) +{ + assert(ppfx != NULL); + assert(ppfy != NULL); + + Ulong m,n,h,cols; + long i,k; + Uint j,l,r; + + R score,h_score; + + // alloc space for the score matrix, backtrack structure and , if wanted, for the calculation-order-matrix + m_mtrxSize=ppfx->getNumCSFs()*ppfy->getNumCSFs(); + + m_mtrx=new R[m_mtrxSize]; + m_rowStart=new Ulong[ppfx->getNumCSFs()]; + m_ppfx = new PPForest(*ppfx); // copy the ppforests + m_ppfy = new PPForest(*ppfy); + m_alg=&alg; + m_rnaAlg=NULL; + m_localOptimum=alg.worst_score(); + + + // initialize variables + m=ppfx->size(); + n=ppfy->size(); + cols=ppfy->getNumCSFs(); + + m_rowStart[0]=0; + for(h=1;hgetNumCSFs();h++) + m_rowStart[h]=m_rowStart[h-1]+cols; + + // align forests fx and fy + + // the easiest case .. + setMtrxVal(0,0,alg.empty()); + + // align fx to the empty forest (fill first row of array) + for(i=m-1;i>=0;i--) // for all nodes in fx + { + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + { + score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),0), + getMtrxVal(ppfx->over(i,j),0)); + + setMtrxVal(ppfx->indexpos(i,j),0,score); + } + } + + // align fy to the empty forest (fill first column of array) + for(k=n-1;k>=0;k--) // for all nodes in fx + { + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + score = alg.insert(getMtrxVal(0,ppfy->down(k)), + ppfy->label(k), + getMtrxVal(0,ppfy->over(k,l))); + + setMtrxVal(0,ppfy->indexpos(k,l),score); + } + } + + // align the rest + for(i=m-1;i>=0;i--) // for all nodes in fx + for(k=n-1;k>=0;k--) // for all nodes in fx + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + // replace + score = alg.replace(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->over(i,j),ppfy->over(k,l))); + + // delete + if(ppfx->noc(i)==0 && !noSpeedup) // no child + { + h_score = alg.del(ppfx->label(i),0, + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfx->rb(i)==0 && !noSpeedup) // no right brother + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,l)), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,r)), + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(h,l-r))); + + score=alg.choice(score,h_score); + h=ppfy->rb(h); + } + } + } + + // insert + if(ppfy->noc(k)==0 && !noSpeedup) // no child + { + h_score = alg.insert(0, + ppfy->label(k), + getMtrxVal(ppfx->indexpos(i,j),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfy->rb(k)==0 && !noSpeedup) // no right brother + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,j),ppfy->down(k)), + ppfy->label(k), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,r),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->indexpos(h,j-r),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + h=ppfx->rb(h); + } + } + } + + // set value + setMtrxVal(ppfx->indexpos(i,j),ppfy->indexpos(k,l),score); + } + + /* + // delete + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,r)), + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(h,l-r))); + + score=alg.choice(score,h_score); + h=ppfy->rb(h); + } + + // insert + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,r),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->indexpos(h,j-r),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + h=ppfx->rb(h); + } + + // set value + setMtrxVal(ppfx->indexpos(i,j),ppfy->indexpos(k,l),score); + */ + + + // showArray(m_mtrx,ppfx->getNumCSFs(),ppfy->getNumCSFs()); + resetOptLocalAlignment(100); +} + +template +void Alignment::calculateGlobal(const PPForest *ppfx, const PPForest *ppfy, const Algebra &alg, bool noSpeedup) +{ + assert(ppfx != NULL); + assert(ppfy != NULL); + + Ulong m,n,h,cols; + long i,k; + Uint j,l,r; + + R score,h_score; + + // alloc space for the score matrix, backtrack structure and , if wanted, for the calculation-order-matrix + m_mtrxSize=ppfx->getNumCSFs()*ppfy->getNumCSFs(); + + m_mtrx=new R[m_mtrxSize]; + m_rowStart=new Ulong[ppfx->getNumCSFs()]; + m_ppfx = new PPForest(*ppfx); // copy the ppforests + m_ppfy = new PPForest(*ppfy); + m_alg=&alg; + m_rnaAlg=NULL; + m_localOptimum=alg.worst_score(); + + + // initialize variables + m=ppfx->size(); + n=ppfy->size(); + cols=ppfy->getNumCSFs(); + + m_rowStart[0]=0; + for(h=1;hgetNumCSFs();h++) + m_rowStart[h]=m_rowStart[h-1]+cols; + + // align forests fx and fy + + // the easiest case .. + setMtrxVal(0,0,alg.empty()); + + // align fx to the empty forest (fill first row of array) + for(i=m-1;i>=0;i--) // for all nodes in fx + { + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + { + score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),0), + getMtrxVal(ppfx->over(i,j),0)); + + setMtrxVal(ppfx->indexpos(i,j),0,score); + } + } + + // align fy to the empty forest (fill first column of array) + for(k=n-1;k>=0;k--) // for all nodes in fx + { + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + score = alg.insert(getMtrxVal(0,ppfy->down(k)), + ppfy->label(k), + getMtrxVal(0,ppfy->over(k,l))); + + setMtrxVal(0,ppfy->indexpos(k,l),score); + } + } + + // align the rest + for(i=m-1;i>=0;i--) // for all nodes in fx + for(k=n-1;k>=0;k--) // for all nodes in fx + { + j=ppfx->getMaxLength(i); + for(l=1;l<=ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + // replace + + score = alg.replace(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->over(i,j),ppfy->over(k,l))); + + // delete + if(ppfx->noc(i)==0 && !noSpeedup) // no child + { + h_score = alg.del(ppfx->label(i),0, + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfx->rb(i)==0 && !noSpeedup) // no right brother + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,l)), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,r)), + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(h,l-r))); + + score=alg.choice(score,h_score); + h=ppfy->rb(h); + } + } + } + + // insert + if(ppfy->noc(k)==0 && !noSpeedup) // no child + { + h_score = alg.insert(0, + ppfy->label(k), + getMtrxVal(ppfx->indexpos(i,j),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfy->rb(k)==0 && !noSpeedup) // no right brother + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,j),ppfy->down(k)), + ppfy->label(k), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,r),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->indexpos(h,j-r),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + h=ppfx->rb(h); + } + } + } + + // set value + setMtrxVal(ppfx->indexpos(i,j),ppfy->indexpos(k,l),score); + } + + l=ppfy->getMaxLength(k); + for(j=1;j<=ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + { + // replace + score = alg.replace(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->over(i,j),ppfy->over(k,l))); + + // delete + if(ppfx->noc(i)==0 && !noSpeedup) // no child + { + h_score = alg.del(ppfx->label(i),0, + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfx->rb(i)==0 && !noSpeedup) // no right brother + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,l)), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = alg.del(ppfx->label(i), + getMtrxVal(ppfx->down(i),ppfy->indexpos(k,r)), + getMtrxVal(ppfx->over(i,j),ppfy->indexpos(h,l-r))); + + score=alg.choice(score,h_score); + h=ppfy->rb(h); + } + } + } + + // insert + if(ppfy->noc(k)==0 && !noSpeedup) // no child + { + h_score = alg.insert(0, + ppfy->label(k), + getMtrxVal(ppfx->indexpos(i,j),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + } + else + { + if(ppfy->rb(k)==0 && !noSpeedup) // no right brother + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,j),ppfy->down(k)), + ppfy->label(k), + 0); + + score=alg.choice(score,h_score); + } + else + { + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = alg.insert(getMtrxVal(ppfx->indexpos(i,r),ppfy->down(k)), + ppfy->label(k), + getMtrxVal(ppfx->indexpos(h,j-r),ppfy->over(k,l))); + + score=alg.choice(score,h_score); + h=ppfx->rb(h); + } + } + } + + // set value + setMtrxVal(ppfx->indexpos(i,j),ppfy->indexpos(k,l),score); + } + } + + // showArray(m_mtrx,ppfx->getNumCSFs(),ppfy->getNumCSFs()); + resetOptLocalAlignment(100); +} + +template +Uint Alignment::backtrack(PPForestAli &ppf,Uint i, Uint j, Uint k, Uint l, Uint &node) +{ + R score, h_score; + Uint p_node,rb_node,noc,rbs,r,h; + + // empty alignment + if(j==0 && l==0) + { + return 0; + } + + score = getMtrxVal(m_ppfx->indexpos(i,j),m_ppfy->indexpos(k,l)); + p_node=node; + node++; + + // could it be a replacement + if(j>0 && l>0) + { + // check for basepair replacement only if Algebra is of type RNA_Algebra + if(m_rnaAlg && m_ppfx->down(i) && m_ppfy->down(k)) + { + h_score = m_rnaAlg->replacepair(m_ppfx->label(i+1), + m_ppfy->label(k+1), + getMtrxVal(m_ppfx->mdown(i),m_ppfy->mdown(k)), + m_ppfx->label(m_ppfx->getRightmostBrotherIndex2(i+1)), + m_ppfy->label(m_ppfy->getRightmostBrotherIndex2(k+1)), + getMtrxVal(m_ppfx->over(i,j),m_ppfy->over(k,l))); + + if(score == h_score) + { + // it is a basepair replacement + ppf.makeRepLabel(p_node,m_ppfx->label(i),m_ppfy->label(k)); // P + + // set labels of leftmost child + ppf.makeRepLabel(p_node+1,m_ppfx->label(i+1),m_ppfy->label(k+1)); + ppf.setRightBrotherIndex(p_node+1,p_node+1+1); + ppf.setNumChildren(p_node+1,0); // base node has no children + node++; + + // down alignment + assert(m_ppfx->noc(i)>=2); + assert(m_ppfy->noc(k)>=2); + noc=backtrack(ppf,i+1+1,m_ppfx->noc(i)-2,k+1+1,m_ppfy->noc(k)-2,node); // !! mdown !! + ppf.setNumChildren(p_node,noc+2); + + if(noc==0) + { + ppf.setRightBrotherIndex(p_node+1,p_node+1+1); + ppf.setRightBrotherIndex(p_node+1+1,0); + } + else + { + ppf.setRightBrotherIndex(ppf.getRightmostBrotherIndex2(p_node+1+1),node); + } + + + // set labels of leftmost child + ppf.makeRepLabel(node,m_ppfx->label(m_ppfx->getRightmostBrotherIndex2(i+1+1)),m_ppfy->label(m_ppfy->getRightmostBrotherIndex2(k+1+1))); + ppf.setRightBrotherIndex(node,0); + ppf.setNumChildren(node,0); // base node has no children + node++; + rb_node=node; // !! + + // right alignment + rbs=backtrack(ppf,m_ppfx->rb(i),j-1,m_ppfy->rb(k),l-1,node); + if(rbs) + ppf.setRightBrotherIndex(p_node,rb_node); + else + ppf.setRightBrotherIndex(p_node,0); + + return rbs+1; + } + } + else + { + h_score = m_alg->replace(m_ppfx->label(i), + getMtrxVal(m_ppfx->down(i),m_ppfy->down(k)), + m_ppfy->label(k), + getMtrxVal(m_ppfx->over(i,j),m_ppfy->over(k,l))); + + if(score == h_score) + { + // it is a replacement + ppf.makeRepLabel(p_node,m_ppfx->label(i),m_ppfy->label(k)); + + // down alignment + noc=backtrack(ppf,i+1,m_ppfx->noc(i),k+1,m_ppfy->noc(k),node); + ppf.setNumChildren(p_node,noc); + rb_node=node; + + // right alignment + rbs=backtrack(ppf,m_ppfx->rb(i),j-1,m_ppfy->rb(k),l-1,node); + if(rbs) + ppf.setRightBrotherIndex(p_node,rb_node); + else + ppf.setRightBrotherIndex(p_node,0); + + return rbs+1; + } + } + } + + // could it be a deletion + if(j>0) + { + h=k; // h is the node where the suffix of the split begins + for(r=0;r<=l;r++) // for all splits of fy + { + h_score = m_alg->del(m_ppfx->label(i), + getMtrxVal(m_ppfx->down(i),m_ppfy->indexpos(k,r)), + getMtrxVal(m_ppfx->over(i,j),m_ppfy->indexpos(h,l-r))); + + if(score == h_score) + { + // it is a deletion + ppf.makeDelLabel(p_node,m_ppfx->label(i)); + + // down alignment + noc=backtrack(ppf,i+1,m_ppfx->noc(i),k,r,node); + ppf.setNumChildren(p_node,noc); + rb_node=node; + + // right alignment + rbs=backtrack(ppf,m_ppfx->rb(i),j-1,h,l-r,node); + if(rbs) + ppf.setRightBrotherIndex(p_node,rb_node); + else + ppf.setRightBrotherIndex(p_node,0); + + return rbs+1; + } + + // if(rrb(h); + } + } + + // could it be an insertion + if(l>0) + { + h=i; + for(r=0;r<=j;r++) // for all splits of fx + { + h_score = m_alg->insert(getMtrxVal(m_ppfx->indexpos(i,r),m_ppfy->down(k)), + m_ppfy->label(k), + getMtrxVal(m_ppfx->indexpos(h,j-r),m_ppfy->over(k,l))); + + if(score == h_score) + { + // it is an insertion + ppf.makeInsLabel(p_node,m_ppfy->label(k)); + + // down alignment + noc=backtrack(ppf,i,r,k+1,m_ppfy->noc(k),node); + ppf.setNumChildren(p_node,noc); + rb_node=node; + + // right alignment + rbs=backtrack(ppf,h,j-r,m_ppfy->rb(k),l-1,node); + if(rbs) + ppf.setRightBrotherIndex(p_node,rb_node); + else + ppf.setRightBrotherIndex(p_node,0); + + return rbs+1; + } + + // if(rrb(h); + } + } + + // you should never be here + cerr << "Strange things happening in backtrack" << endl; + exit(EXIT_FAILURE); +} + + + +/* ****************************************** */ +/* Public functions */ +/* ****************************************** */ + +template +R Alignment::getGlobalOptimum() +{ + return getMtrxVal(m_ppfx->indexpos(0,m_ppfx->getMaxLength(0)),m_ppfy->indexpos(0,m_ppfy->getMaxLength(0))); +}; + +template +double Alignment::getGlobalOptimumRelative() +{ + double opt; + double max_x,max_y; + + opt=(double)getGlobalOptimum(); + + if(m_rnaAlg) + { + max_x=(double)m_ppfx->maxScore(*m_rnaAlg); + max_y=(double)m_ppfy->maxScore(*m_rnaAlg); + } + else + { + max_x=(double)m_ppfx->maxScore(*m_alg); + max_y=(double)m_ppfy->maxScore(*m_alg); + } + + assert(max_x+max_y>0); + opt=2*opt/(max_x+max_y); + + return opt; +}; + +template +R Alignment::getSILOptimum() +{ + R silOptimum; + int k=0; + Uint j,l=0; + Ulong n; + + n=m_ppfy->size(); + + if(m_rnaAlg) + silOptimum=m_rnaAlg->worst_score(); + else + silOptimum=m_alg->worst_score(); + + j=m_ppfx->getMaxLength(0); + + // find the best match + for(k=n-1;k>=0;k--) // for all nodes in fx + for(l=1;l<=m_ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + silOptimum=m_alg->choice(silOptimum,getMtrxVal(m_ppfx->indexpos(0,j),m_ppfy->indexpos(k,l))); + } + + return silOptimum; +} + +template +void Alignment::getOptGlobalAlignment(PPForestAli &ppfali) +{ + Uint node=0; + + // allocate a forest of the maximal size that a forest alignment can have + ppfali.initialize(m_ppfx->size()+m_ppfy->size()); + backtrack(ppfali,0,m_ppfx->getMaxLength(0),0,m_ppfy->getMaxLength(0),node); + ppfali.setSize(node); + ppfali.calcSumUpCSF(); + ppfali.calcRMB(); +} + +template +void Alignment::resetOptLocalAlignment(int suboptimalsPercent) +{ + m_localAlis.clear(); + m_suboptimalsPercent=suboptimalsPercent/100.0; + m_localSubOptimum=m_localOptimum; +}; + +// calculate the score of the next best local alignment that is not "included" +// in a local alignment returned by getOptLocalAlignment before +template +bool Alignment::nextLocalSuboptimum() +{ + Ulong m,n; + int i=0,k=0; + Uint j=0,l=0; + + m_localSubOptimum=m_alg->worst_score(); + m=m_ppfx->size(); + n=m_ppfy->size(); + + // find a matrix element that is optimal + for(i=m-1;i>=0;i--) // for all nodes in fx + for(k=n-1;k>=0;k--) // for all nodes in fx + for(j=1;j<=m_ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + for(l=1;l<=m_ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + bool disjoint=true; + + // check if i,j,k,l is included + typename list::const_iterator it; + for(it=m_localAlis.begin();it!=m_localAlis.end();it++) + { + if(!m_ppfx->isDisjoint(it->i,it->j,i,j) || !m_ppfy->isDisjoint(k,l,it->k,it->l)) + { + disjoint=false; + break; + } + + } + + if(disjoint) + { + if(getMtrxVal(m_ppfx->indexpos(i,j),m_ppfy->indexpos(k,l))>=m_suboptimalsPercent*m_localOptimum) + m_localSubOptimum=m_alg->choice(m_localSubOptimum,getMtrxVal(m_ppfx->indexpos(i,j),m_ppfy->indexpos(k,l))); + } + } + + return m_localSubOptimum!=m_alg->worst_score(); +} + +template +void Alignment::getOptLocalAlignment(PPForestAli &ppfali,Uint &xbasepos, Uint &ybasepos) +{ + Ulong m,n; + int i=0,k=0; + Uint j=0,l=0,node=0; + + m=m_ppfx->size(); + n=m_ppfy->size(); + // allocate a forest of the maximal size that a forest alignment can have + ppfali.initialize(m_ppfx->size()+m_ppfy->size()); + + // find a matrix element that is optimal + for(i=m-1;i>=0;i--) // for all nodes in fx + for(k=n-1;k>=0;k--) // for all nodes in fx + for(j=1;j<=m_ppfx->getMaxLength(i);j++) // for all non empty csfs induced by i + for(l=1;l<=m_ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + bool disjoint=true; + + // check if i,j,k,l is included + typename list::const_iterator it; + for(it=m_localAlis.begin();it!=m_localAlis.end();it++) + { + if(!m_ppfx->isDisjoint(it->i,it->j,i,j) || !m_ppfy->isDisjoint(k,l,it->k,it->l)) + { + disjoint=false; + break; + } + + } + + if(disjoint && getMtrxVal(m_ppfx->indexpos(i,j),m_ppfy->indexpos(k,l)) == m_localSubOptimum) + goto found; + } + + found: + backtrack(ppfali,i,j,k,l,node); + ppfali.setSize(node); + ppfali.calcSumUpCSF(); + ppfali.calcRMB(); + + m_localAlis.push_back(CSFPair(i,j,k,l)); + xbasepos=m_ppfx->countLeaves(i); + ybasepos=m_ppfy->countLeaves(k); +} + +template +void Alignment::getOptSILAlignment(PPForestAli &ppfali,Uint &ybasepos) +{ + R silOptimum; + Ulong m,n; + int k=0; + Uint j=0,l=0,node=0; + + m=m_ppfx->size(); + n=m_ppfy->size(); + // allocate a forest of the maximal size that a forest alignment can have + ppfali.initialize(m_ppfx->size()+m_ppfy->size()); + + silOptimum=getSILOptimum(); + j=m_ppfx->getMaxLength(0); + + // find a matrix element that is optimal + for(k=n-1;k>=0;k--) // for all nodes in fx + for(l=1;l<=m_ppfy->getMaxLength(k);l++) // for all non empty csfs induced by k + { + if(silOptimum == getMtrxVal(m_ppfx->indexpos(0,j),m_ppfy->indexpos(k,l))) + goto found; + } + + found: + backtrack(ppfali,0,j,k,l,node); + ppfali.setSize(node); + ppfali.calcSumUpCSF(); + ppfali.calcRMB(); + + ybasepos=m_ppfy->countLeaves(k); +} + + +#endif + + + + + + + + + + + + + + + + + + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/debug.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/debug.h new file mode 100755 index 00000000..88dc2873 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/debug.h @@ -0,0 +1,30 @@ +#ifndef _DEBUG_H_ +#define _DEBUG_H_ + +#include + +#ifndef RNAF_DEBUGLEVEL + #define RNAF_DEBUGLEVEL 5 +#endif + +#define DBG_OFF 6 +#define DBG_QWATCH 1 + +// program intern debug levels +#define DBG_BACKTRACK DBG_OFF +#define DBG_GET_PROFILE_STRUCTURE DBG_OFF +#define DBG_ALGEBRA DBG_OFF +#define DBG_ALIGNMENT DBG_OFF +#define DBG_MULTIPLE DBG_OFF + +#ifdef NDEBUG + #define TRACE(L,C,M) + #define WATCH(L,C,M) + #define QWATCH(L,C,M) +#else + #define TRACE(L,C,M) if(L <= RNAF_DEBUGLEVEL) cout << C << " - " << M << endl; + #define WATCH(L,C,M) if(L <= RNAF_DEBUGLEVEL) cout << C << " - " << #M << ": " << M << endl; + #define QWATCH(M) if(DBG_QWATCH <= RNAF_DEBUGLEVEL) cout << #M << ": " << M << endl; +#endif + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold.h new file mode 100755 index 00000000..703aa2d0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold.h @@ -0,0 +1,8 @@ +/* function from fold.c */ +extern float fold(const char *sequence, char *structure); +/* calculate mfe-structure of sequence */ +extern float energy_of_struct(const char *string, const char *structure); +/* calculate energy of string on structure */ +extern void free_arrays(void); /* free arrays for mfe folding */ +extern void initialize_fold(int length); /* allocate arrays for folding */ +extern void update_fold_params(void); /* recalculate parameters */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold_vars.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold_vars.h new file mode 100755 index 00000000..243f5046 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/fold_vars.h @@ -0,0 +1,37 @@ +/* to use floats instead of doubles in pf_fold() comment next line */ +#define LARGE_PF +#ifdef LARGE_PF +#define FLT_OR_DBL double +#else +#define FLT_OR_DBL float +#endif + +extern int noGU; /* GU not allowed at all */ +extern int no_closingGU; /* GU allowed only inside stacks */ +extern int tetra_loop; /* Fold with specially stable 4-loops */ +extern int energy_set; /* 0 = BP; 1=any mit GC; 2=any mit AU-parameter */ +extern int dangles; /* use dangling end energies (not in part_func!) */ +/*@null@*/ +extern char *nonstandards; /* contains allowed non standard bases */ +extern double temperature; /* rescale parameters to this temperature */ +extern int james_rule; /* interior loops of size 2 get energy 0.8Kcal and + no mismatches, default 1 */ +extern int logML; /* use logarithmic multiloop energy function */ +extern int cut_point; /* first position of 2nd strand for co-folding */ + +struct bond { /* base pair */ + int i; + int j; +}; +typedef struct bond bondT; +extern bondT *base_pair; /* list of base pairs */ + +extern FLT_OR_DBL *pr; /* base pairing prob. matrix */ +extern int *iindx; /* pr[i,j] -> pr[iindx[i]-j] */ +extern double pf_scale; /* scaling factor to avoid float overflows*/ +extern int fold_constrained; /* fold with constraints */ +extern int do_backtrack; /* calculate pair prob matrix in part_func() */ +extern int noLonelyPairs; /* avoid helices of length 1 */ +extern char backtrack_type; /* usually 'F'; 'C' require (1,N) to be bonded; + 'M' seq is part of a multi loop */ +char * option_string(void); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/glib.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/glib.c new file mode 100755 index 00000000..ea99e521 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/glib.c @@ -0,0 +1,355 @@ +#include "graphtypes.h" +#include +#include +#include + +void AddEdge (Graph g,int n,int m,int label) +{ Edge edge1,edge2; + + edge1 = (Edge) malloc(2*sizeof(struct edge_ent)); + edge2 = edge1 + 1; + + edge1->label = label; + edge1->endpoint = m; + edge1->otheredge = edge2; + edge1->prevedge = NULL; + edge1->nextedge = g[n].adj_list; + if (edge1->nextedge != NULL) + edge1->nextedge->prevedge = edge1; + g[n].adj_list = edge1; + g[n].degree++; + + edge2->label = label; + edge2->endpoint = n; + edge2->otheredge = edge1; + edge2->prevedge = NULL; + edge2->nextedge = g[m].adj_list; + if (edge2->nextedge != NULL) + edge2->nextedge->prevedge = edge2; + g[m].adj_list = edge2; + g[m].degree++; +} + +Edge FindEdge(Graph graph,int i,int j) +{ Edge edge; + + edge = graph[i].adj_list; + while (edge!=NULL && edge->endpoint!=j) + edge = edge->nextedge; + if (edge==NULL) return(NULL); + else return(edge); +} + +int RemoveEdge(Graph graph,Edge edge) +{ Edge other; + int i,j; + + if (edge==NULL) return(0); + other = edge->otheredge; + i = other->endpoint; + j = edge->endpoint; + graph[i].degree--; graph[j].degree--; + if (edge->prevedge == NULL) { + graph[i].adj_list = edge->nextedge; + if (edge->nextedge != NULL) + edge->nextedge->prevedge = NULL; + } + else if (edge->nextedge == NULL) + (edge->prevedge)->nextedge = NULL; + else { + (edge->nextedge)->prevedge = edge->prevedge; + (edge->prevedge)->nextedge = edge->nextedge; + } + if (other->prevedge == NULL) { + graph[j].adj_list = other->nextedge; + if (other->nextedge != NULL) + other->nextedge->prevedge = NULL; + } + else if (other->nextedge == NULL) + (other->prevedge)->nextedge = NULL; + else { + (other->nextedge)->prevedge = other->prevedge; + (other->prevedge)->nextedge = other->nextedge; + } + free((edge < other) ? edge : other); + return(1); +} + +int NumEdges(Graph g) +{ int i,size,edges; + + edges = 0; + size = Degree(g,0); + for (i=1; i<=size; i++) + edges += Degree(g,i); + edges /= 2; + return(edges); +} + +Graph NewGraph(int size) +{ Graph tmp; + int i; + + tmp = (Graph) malloc((size+1)*sizeof(struct node_entry)); + for (i=1; i<=size; i++) { + Degree(tmp,i) = 0; + FirstEdge(tmp,i) = NULL; + NLabel(tmp,i) = i; + } + Degree(tmp,0) = size; + return(tmp); +} + +EuclidGraph NewEuclid(int size) +{ + EuclidGraph xy; + + xy = (EuclidGraph) malloc((size+1)*2*sizeof(int)); + xy[0][0] = size; + return(xy); +} + +MatrixGraph NewMatrix(int size) +{ + MatrixGraph graph; + int i; + + graph = (MatrixGraph) malloc((size*(size+1)+1)*sizeof(int)); + graph[0] = size; + + for (i=1; i<=size; i++) /* zero the diagonal */ + graph[i*(size+1)] = 0; + + return(graph); +} + +Graph CopyGraph(Graph g) +{ int i,j,size; + Edge edge; + Graph cp; + + size = Degree(g,0); + cp = NewGraph(size); + for (i=1; i<=size; i++) { + Xcoord(cp,i) = Xcoord(g,i); + Ycoord(cp,i) = Ycoord(g,i); + edge = FirstEdge(g,i); + for (j=1; j<=Degree(g,i); j++) { + if (i < EndPoint(edge)) + AddEdge(cp,i,EndPoint(edge),ELabel(edge)); + edge = NextEdge(edge); + } + } + return (cp); +} + +/* Graph I/O routines */ + +Graph ReadGraph (int *size,char *file) +{ Graph graph; + FILE *fp; + char c; + int edges, degree, vlabel, elabel, adj_node, i, j; + int xcoord, ycoord; + + if (file[0] == '\0') fp = stdin; + else fp = fopen(file,"r"); + if (fp==NULL) { + printf("ReadGraph: file %s can't be opened\n",file); + exit(0); + } + fscanf(fp,"%d%d %c",size,&edges,&c); + if (c !='U' && c!='u') { + printf("ReadGraph: file %s does not contain an undirected graph\n",file); + exit(0); + } + while (getc(fp)!='\n') ; + + graph = NewGraph(*size); + for (i = 1; i <= *size; ++i) { + fscanf(fp,"%d%d%d%d",°ree,&vlabel,&xcoord,&ycoord); + NLabel(graph,i) = vlabel; + Xcoord(graph,i) = xcoord; + Ycoord(graph,i) = ycoord; + while (getc(fp)!='\n') ; + for (j = 1; j <= degree; ++j) { + fscanf(fp,"%d%d", &adj_node, &elabel); + while (getc(fp)!='\n') ; + if (i>1; + l = (l + k/l)>>1; + l = (l + k/l)>>1; + l = (l + k/l)>>1; + return ((l*l .000000001) ? l+1 : l); +} + + +int eucdistsq(EuclidGraph graph,int i,int j) /* Find the square of the dist between two points */ +{ + register int dv,dh; + + dv = graph[i][0]-graph[j][0]; + dh = graph[i][1]-graph[j][1]; + return(dv*dv+dh*dh); +} + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/glib.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/glib.o new file mode 100755 index 0000000000000000000000000000000000000000..656641e8d5ebdf1a22381441c304d5c10cd1fffc GIT binary patch literal 13864 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zo)HIav?l|}&QQj5uJzmlCo`C;Z=%ug}z VW&R~|ym-Mrr6v7X9!LB6^1l}hwOIfF literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/graphtypes.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/graphtypes.h new file mode 100755 index 00000000..4bf4b832 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/graphtypes.h @@ -0,0 +1,89 @@ +#ifndef _GRAPHTYPES_H_ +#define _GRAPHTYPES_H_ + +#define INF 100000000 + +#ifndef NULL +#define NULL 0 +#endif + +struct node_entry { + int degree; + int label; + int x; + int y; + struct edge_ent *adj_list; + }; +typedef struct node_entry *Graph; + +struct edge_ent { + int endpoint; + int label; + int label2; + struct edge_ent *nextedge; + struct edge_ent *prevedge; + struct edge_ent *otheredge; + }; +typedef struct edge_ent *Edge; + +#define Degree(graph,n) (graph[n].degree) +#define NLabel(graph,n) (graph[n].label) +#define Xcoord(graph,n) (graph[n].x) +#define Ycoord(graph,n) (graph[n].y) +#define FirstEdge(graph,n) (graph[n].adj_list) + +#define EndPoint(e) (e->endpoint) +#define ELabel(e) (e->label) +#define ELabel2(e) (e->label2) +#define Other(e) (e->otheredge) +#define NextEdge(e) (e->nextedge) + + +extern Graph Prim(); +//extern int *EulerTraverse(),*Match(),*Weighted_Match(),*Dijkstra(),*Concomp(); + +/* Euclidean graph type */ +typedef int (*EuclidGraph)[2]; + +extern Graph EuclidPrim(); +extern EuclidGraph ReadEuclid(),NewEuclid(); +extern int eucdist(),eucdistsq(); + +extern int *CvxHull(); + +/* Distance matrix graph type */ +typedef int *MatrixGraph; + +extern int *MatrixDijkstra(); +extern Graph MatrixPrim(); +extern Graph MatrixMaxFlow(); +extern MatrixGraph ReadMatrix(), NewMatrix(); + +#ifdef __cplusplus +extern "C" +{ +#endif + +void AddEdge (Graph g,int n,int m,int label); +Edge FindEdge(Graph graph,int i,int j); +int RemoveEdge(Graph graph,Edge edge); +int NumEdges(Graph g); +Graph NewGraph(int size); +EuclidGraph NewEuclid(int size); +MatrixGraph NewMatrix(int size); +Graph CopyGraph(Graph g); +Graph ReadGraph (int *size,char *file); +void WriteGraph (Graph graph,char *file); +EuclidGraph ReadEuclid(int *size,char *file); +void WriteEuclid(EuclidGraph graph,char *file); +MatrixGraph ReadMatrix(int *size,char *file); +void WriteMatrix(MatrixGraph graph,char *file); +int eucdist (EuclidGraph graph,int i,int j); +int eucdist2 (EuclidGraph graph,int i,int j); +int eucdistsq(EuclidGraph graph,int i,int j); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/main.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/main.cpp new file mode 100755 index 00000000..0bd48771 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/main.cpp @@ -0,0 +1,908 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include + +//#include +#include +#include + +#ifndef WIN32 +#include "config.h" +#endif + +#include "Arguments.h" +#include "alignment.h" +#include "debug.h" + +//#include "global_alignment.h" +#include "treeedit.h" + +#include "misc.h" +#include "progressive_align.h" +#include "rna_alignment.h" +#include "rnaforest.h" +#include "rnaforestsz.h" +#include "rnafuncs.h" +#include "rna_profile_alignment.h" +#include "rna_algebra.h" +#include "rnaforester_options.h" + + +#include "alignment.t.cpp" +//#include "global_alignment.t.cpp" +#include "treeedit.t.cpp" +//#include "ppforest.t.cpp" + +using namespace std; + +/* ****************************************** */ +/* Definitions and typedefs */ +/* ****************************************** */ + +struct ToLower : public unary_function { + char operator()(char a) + { + return tolower(a); + }; +}; + +template +void makeDotFileAli(const PPForest &ppf, const RNAforesterOptions &options) +{ + if(options.has(RNAforesterOptions::OutputAlignmentDotFormat)) + { + string filename; + options.get(RNAforesterOptions::OutputAlignmentDotFormat,filename,string("ali.dot")); + ofstream s(filename.c_str()); + ppf.printDot(s); + } +} + +template +void makeDotFileInp(const PPForest &ppf, const RNAforesterOptions &options, Uint count) +{ + if(options.has(RNAforesterOptions::MakeDotForInputTrees)) + { + ostringstream ss; + ofstream os; + ss << "input" << count << ".dot"; + os.open(ss.str().c_str()); + ppf.printDot(os); + os.close(); + } +} + +static const string RNAFORESTER_VERSION = "1.5"; +static const string PROMPT = "Input string (upper or lower case); & to end for multiple alignments, @ to quit\n"; +static const string SCALE = "....,....1....,....2....,....3....,....4....,....5....,....6....,....7....,....8\n"; + +void alignMultiple(deque &alignList, Score &score,const RNAforesterOptions &options); +void alignPairwise(deque &inputListPW,Score &score,const RNAforesterOptions &options); +void cutAfterChar(string &s,char c); + +void editPairwise(list &inputListSZ,Score &score,RNAforesterOptions &options); +void alignPairwiseSimple(deque &inputListPW,Score &score,RNAforesterOptions &options); + +static void showversion(const char *prog) +{ + cout << prog << ", version " << RNAFORESTER_VERSION << endl; + cout << "Copyright Matthias Hoechsmann 2001-2004," << endl << "mhoechsm@techfak.uni-bielefeld.de" << endl; +} + +int main(int argc, const char **argv) +{ + string buffer; + string baseStr,viennaStr,nameStr; + Ulong basePairCount,maxDepth; + deque inputListPW; + deque alignList; + bool showScale=true,multipleAlign=false; + istream *inputStream=NULL; + ifstream *inputFile=NULL; + Uint structure_count=1; + int suboptPercent=100; + double minPairProb=0.25; + + list inputListSZ; + + try + { + RNAforesterOptions options(argc,argv); + + // check options + if(options.has(RNAforesterOptions::Help)) + { + options.help(); + exit(EXIT_SUCCESS); + } + + if(options.has(RNAforesterOptions::SecretHelp)) + { + options.secretHelp(); + exit(EXIT_SUCCESS); + } + + if(options.has(RNAforesterOptions::Version)) + { + showversion(argv[0]); + exit(EXIT_SUCCESS); + } + + // read score values + Score score(options); + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + score.print(); + + // check option suboptimals + if(options.has(RNAforesterOptions::LocalSubopts)) + { + options.get(RNAforesterOptions::LocalSubopts,suboptPercent,100); + if(suboptPercent<0 || suboptPercent>100) + { + cerr << "error: value for parameter --subopts must be in range from 0 to 100" << endl; + exit(EXIT_FAILURE); + } + } + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + options.get(RNAforesterOptions::PredictMinPairProb,minPairProb,0.25); + if(options.has(RNAforesterOptions::PredictProfile)) + cout << "Minumim required basepair probability (-pmin): " << minPairProb << endl; +#endif + + // show if suboptimals + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + if(options.has(RNAforesterOptions::LocalSimilarity) && options.has(RNAforesterOptions::LocalSubopts)) + cout << "calculate suboptimals within " << suboptPercent << "% of global optimum" << endl << endl; + + // profile search + if(options.has(RNAforesterOptions::ProfileSearch)) + { + string filename; + + options.get(RNAforesterOptions::ProfileSearch,filename,string("")); + if(filename=="") + { + cerr << "no profile filename" << endl; + exit(EXIT_FAILURE); + } + + RNAProfileAlignment *rnaProfileAli=new RNAProfileAlignment(filename); + alignList.push_back(rnaProfileAli); + } + + if(options.has(RNAforesterOptions::ReadFromFile)) + { + string filename; + options.get(RNAforesterOptions::ReadFromFile,filename,string("")); + inputFile=new ifstream(filename.c_str()); + if(inputFile->fail()) + { + cerr << "cannot open file: \"" << filename << "\"" << endl; + exit(EXIT_FAILURE); + } + inputStream=inputFile; + } + else + { + inputStream=&cin; + } + + + if(showScale) + { + if(!options.has(RNAforesterOptions::NoScale) && !options.has(RNAforesterOptions::ReadFromFile)) + cout << endl << PROMPT << SCALE; + showScale=false; + } + + for(;;) + { + getline(*inputStream,buffer); + + if(inputStream->eof()) + { + if(options.has(RNAforesterOptions::Multiple) && !options.has(RNAforesterOptions::ProfileSearch)) + buffer="&"; + else + exit(EXIT_SUCCESS); + } + + if(buffer.empty()) + continue; + + // quit if character is @ + if(buffer[0]=='@') + break; + + // delete '\r' at line end from non unix files + if(buffer[buffer.size()-1]=='\r') + buffer.erase(buffer.size()-1); + + // check for name of structure + if(buffer[0]=='>') + { + nameStr=&buffer[1]; + continue; + } + + // cut after blank + cutAfterChar(buffer,' '); + + // check for aligning multiple structures + // if input is read from file the eof has the same meaning as & + if( buffer[0]=='&') + multipleAlign=true; + else + { + // check for base string + + if(RNAFuncs::isRNAString(buffer)) + { + baseStr=buffer; + // convert to small letters + transform(baseStr.begin(),baseStr.end(),baseStr.begin(),ToLower()); + // t -> u + replace(baseStr.begin(),baseStr.end(),'t','u'); + // delete '.' and '-' from alignment files + remove(baseStr.begin(),baseStr.end(),'.'); + remove(baseStr.begin(),baseStr.end(),'-'); + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + if(options.has(RNAforesterOptions::PredictProfile)) + { + ostringstream ss; + string constraint; + + // if there is no name given (> ...) use a counter + if(nameStr=="") + ss << "> " << structure_count; + else + ss << nameStr; + + cout << "Predicting structure profile for sequence: " << ss.str() << endl; + RNAProfileAlignment *rnaProfileAli=new RNAProfileAlignment(baseStr,ss.str(),constraint,minPairProb); + alignList.push_back(rnaProfileAli); + makeDotFileInp(*rnaProfileAli,options,structure_count); + structure_count++; + } +#endif + + // continue; + } + else + { + + // check for vienna string + if(RNAFuncs::isViennaString(buffer,basePairCount,maxDepth)) + { + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + // skip structure lines if structures are predicted + if(options.has(RNAforesterOptions::PredictProfile)) + { + cout << "ignoring structure: " << buffer << endl; + continue; + } +#endif + + viennaStr=buffer; + } + else + { + cerr << "The input sequence is neither an RNA/DNA string nor in vienna format." << endl; + cerr << "line: " << buffer << endl; + showScale=true; + exit(EXIT_FAILURE); + } + + // add structure to input list + if(options.has(RNAforesterOptions::Multiple)) + { + ostringstream ss; + + // if there is no name given (> ...) use a counter + if(nameStr=="") + ss << "> " << structure_count; + else + ss << nameStr; + + + RNAProfileAlignment *rnaProfileAli=new RNAProfileAlignment(baseStr,viennaStr,ss.str()); + makeDotFileInp(*rnaProfileAli,options,structure_count); + alignList.push_back(rnaProfileAli); + } + else + { + if(options.has(RNAforesterOptions::TreeEdit)) + { + RNAForestSZ *rnaForestSZ=new RNAForestSZ(baseStr,viennaStr,nameStr); + inputListSZ.push_back(rnaForestSZ); + } + else + { + RNAForest *rnaForest=new RNAForest(baseStr,viennaStr,nameStr); + nameStr=""; + makeDotFileInp(*rnaForest,options,structure_count); + inputListPW.push_back(rnaForest); + } + } + + structure_count++; + showScale=true; + } + } + + // ***** multiple alignment + if((options.has(RNAforesterOptions::Multiple) && multipleAlign) || (options.has(RNAforesterOptions::ProfileSearch) && alignList.size()==2)) + { + alignMultiple(alignList,score,options); + multipleAlign=false; + structure_count=1; + + if(options.has(RNAforesterOptions::ProfileSearch)) + { + string filename; + + options.get(RNAforesterOptions::ProfileSearch,filename,string("")); + RNAProfileAlignment *rnaProfileAli=new RNAProfileAlignment(filename); + alignList.push_back(rnaProfileAli); + } + else + break; + + // break; + } + + // ***** pairwise alignment + if(inputListPW.size()==2) + { + if(options.has(RNAforesterOptions::GlobalAlignment)) + alignPairwiseSimple(inputListPW,score,options); + else + alignPairwise(inputListPW,score,options); + break; + } + + if(inputListSZ.size()==2) + { + editPairwise(inputListSZ,score,options); + break; + } + + } + + // free dynamic allocated memory + deque::const_iterator it; + for(it = inputListPW.begin(); it!=inputListPW.end(); it++) + delete *it; + + DELETE(inputFile); + + // getchar(); // only for testing + return (0); + } + catch(RNAforesterOptions::IncompatibleException e) + { + e.showError(); + return(EXIT_FAILURE); + } + catch(RNAforesterOptions::RequiresException e) + { + e.showError(); + return(EXIT_FAILURE); + } +} + + + +void cutAfterChar(string &s,char c){ + string::size_type pos=s.find(c); + if(pos!=string::npos) + s.erase(pos); +} + +void alignMultiple(deque &alignList, Score &score,const RNAforesterOptions &options) +{ + DoubleScoreProfileAlgebraType *alg; + deque > resultList; +// double optScore; + Uint clusterNr=1; + double minPairProb; + + options.get(RNAforesterOptions::ConsensusMinPairProb,minPairProb,0.5); + + // distance or similarity + if(options.has(RNAforesterOptions::CalculateDistance)) + alg=new DoubleDistProfileAlgebra(score); + else + alg=new DoubleSimiProfileAlgebra(score); + + cout << endl; + + progressiveAlign(alignList,resultList,alg,options); + + cout << endl; + cout << "*** Results ***" << endl << endl; + cout << "Minimum basepair probability for consensus structure (-cmin): " << minPairProb << endl << endl; + + deque >::const_iterator it; + for(it=resultList.begin();it!=resultList.end();it++) + { + cout << "RNA Structure Cluster Nr: " << clusterNr << endl; + cout << "Score: " << it->first << endl; + cout << "Members: " << it->second->getNumStructures() << endl << endl; + + if(options.has(RNAforesterOptions::FastaOutput)) + { + it->second->printFastaAli(false); + cout << endl; + } + else + { + + it->second->printSeqAli(); + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + // print alignment + it->second->printStrAli(); + cout << endl; +#endif + } + + // save profile + if(options.has(RNAforesterOptions::SaveProfile)) + { + string filename; + filename=options.generateFilename(RNAforesterOptions::SaveProfile,".pro", "rna.pro",clusterNr); + it->second->save(filename); + } + + + // print consensus structure + cout << "Consensus sequence/structure:" << endl; + it->second->printConsensus(minPairProb); + cout << endl; + +#ifdef HAVE_LIBG2 // This features require the g2 library + // generate squiggle plots + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + RNAProfileAlignment::SquigglePlotOptions sqOptions; + string filename; + + // plot showing full base information + filename=options.generateFilename(RNAforesterOptions::MakeSquigglePlot,".ps", "rnaprofile.ps",clusterNr); + sqOptions.greyColors=options.has(RNAforesterOptions::SquiggleGreyColors); + sqOptions.minPairProb=minPairProb; + sqOptions.mostLikelySequence=false; + it->second->squigglePlot(filename,sqOptions); + + // plot showing consensus sequence + filename=options.generateFilename(RNAforesterOptions::MakeSquigglePlot,"_cons.ps", "rnaprofile_cs.ps",clusterNr); + sqOptions.mostLikelySequence=true; + it->second->squigglePlot(filename,sqOptions); + } +#endif + + clusterNr++; + } + + + /* + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + { + cout << "global optimal score: "; + } + cout << optScore << endl; + + list::iterator it=inputMapProfile.begin(); + RNAProfileAlignment *ppf=it; + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + { + // generate dot file + makeDotFileAli(*ppf,options); + + ppf->print(); + cout << endl; + ppf->printConsensus(); + } + */ + + // save profile alignment to binary file + /* if(options.has(RNAforesterOptions::SaveMultipleAliFile)) + { + string filename; + + filename=generateFilename(options,RNAforesterOptions::SaveMultipleAliFile,".mta", "unknown.dot"); + ofstream s(filename.c_str()); + f1->save(s); + } + */ + + /* + // generate squiggle plots + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + RNAProfileAlignment::SquigglePlotOptions sqOptions; + string filename; + + // plot showing full base information + filename=options.generateFilename(RNAforesterOptions::MakeSquigglePlot,".ps", "rnaprofile.ps"); + sqOptions.greyColors=options.has(RNAforesterOptions::SquiggleGreyColors); + sqOptions.mostLikelySequence=false; + ppf->squigglePlot(filename,sqOptions); + + // plot showing consensus sequence + filename=options.generateFilename(RNAforesterOptions::MakeSquigglePlot,"_cons.ps", "rnaprofile_cons.ps"); + sqOptions.greyColors=options.has(RNAforesterOptions::SquiggleGreyColors); + sqOptions.mostLikelySequence=true; + ppf->squigglePlot(filename,sqOptions); + } + */ + + + delete alg; +} + + +void alignPairwise(deque &inputListPW,Score &score,const RNAforesterOptions &options) +{ + IntScoreRNA_AlgebraType *alg; + Uint xbasepos,ybasepos,xlen,ylen; + list > xsubopts; + list > ysubopts; + string seq1,seq2,str1,str2; + char s[8]; + int suboptPercent; + Uint count=1; + RNAFuncs::SquigglePlotOptions sqOptions; + tms tmsStart, tmsEnd; + + // read options + options.get(RNAforesterOptions::LocalSubopts,suboptPercent,100); + +#ifdef HAVE_LIBG2 // This features require the g2 library + // generate squiggle plot + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + // get sq options + sqOptions.hideBaseNumbers=options.has(RNAforesterOptions::SquiggleHideBaseNumbers); + options.get(RNAforesterOptions::SquiggleBaseNumberInterval,sqOptions.baseNumInterval,(Uint)20); + sqOptions.greyColors=options.has(RNAforesterOptions::SquiggleGreyColors); + options.get(RNAforesterOptions::SquiggleScaleFactor,sqOptions.scale,1.0); + sqOptions.generateFIG=options.has(RNAforesterOptions::SquiggleGenerateFIG); +#ifdef HAVE_LIBGD + sqOptions.generatePNG=options.has(RNAforesterOptions::SquiggleGeneratePNG); + sqOptions.generateJPG=options.has(RNAforesterOptions::SquiggleGenerateJPG); +#endif + + } +#endif + + // distance or similarity + if(options.has(RNAforesterOptions::CalculateDistance)) + alg=new IntDistRNA_Algebra(score); + else + { + if(options.has(RNAforesterOptions::RIBOSUMScore)) + alg=new RIBOSUM8560(score); + else + alg=new IntSimiRNA_Algebra(score); + } + + RNAForest *f1=inputListPW.front(); + RNAForest *f2=inputListPW.back(); + + if(options.has(RNAforesterOptions::SpaceTimeInfo)) + { + IntScore_AlgebraType *algGlobClassic; + + algGlobClassic=new IntDist_Algebra(score); + + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + { + cout << "F1_NUMNODES" << ";"; + cout << "F2_NUMNODES" << ";"; + cout << "F1_DEGREE" << ";"; + cout << "F2_DEGREE" << ";"; + cout << "F1_LEAVES" << ";"; + cout << "F2_LEAVES" << ";"; + cout << "F1_DEPTH" << ";"; + cout << "F2_DEPTH" << ";"; + cout << "F1_NUMCSFS" << ";"; + cout << "F2_NUMCSFS" << ";"; + cout << "TABLE_SIZE_4D" << ";"; + cout << "TABLE_SIZE_2D" << ";"; + cout << "GLOBALI_TIME" << ";"; + cout << "GLOBALI_TIME_SPEEDUP" << ";"; + cout << "LOCALALI_TIME" << ";"; + cout << "LOCALALI_TIME_SPEEDUP" << ";"; + + cout << endl; + } + + cout << f1->size() << "\t"; + cout << f2->size() << "\t"; + cout << f1->maxDegree() << "\t"; + cout << f2->maxDegree() << "\t"; + cout << f1->numLeaves() << "\t"; + cout << f2->numLeaves() << "\t"; + cout << f1->maxDepth() << "\t"; + cout << f2->maxDepth() << "\t"; + cout << f1->getNumCSFs() << "\t"; + cout << f2->getNumCSFs() << "\t"; + cout << f1->size()*f2->size()*f1->maxDegree()*f1->maxDegree() << "\t"; + cout << f1->getNumCSFs()*f2->getNumCSFs() << "\t"; + + // global alignment + { + times(&tmsStart); + Alignment ali(f1,f2,*algGlobClassic,false,true); + times(&tmsEnd); + cout <<((double) (tmsEnd.tms_utime - tmsStart.tms_utime))/sysconf(_SC_CLK_TCK) << "\t"; + // cerr << "#" << ali.getGlobalOptimum() << "#"; + } + + // global alignment speedup + { + times(&tmsStart); + Alignment ali(f1,f2,*algGlobClassic,false,false); + times(&tmsEnd); + cout <<((double) (tmsEnd.tms_utime - tmsStart.tms_utime))/sysconf(_SC_CLK_TCK) << "\t"; + // cerr << "#" << ali.getGlobalOptimum() << "#"; + } + + // local alignment + { + times(&tmsStart); + Alignment ali(f1,f2,*algGlobClassic,true,true); + times(&tmsEnd); + cout <<((double) (tmsEnd.tms_utime - tmsStart.tms_utime))/sysconf(_SC_CLK_TCK) << "\t"; + // cerr << "#" << ali.getLocalOptimum() << "#"; + } + + // local alignment speedup + { + times(&tmsStart); + Alignment ali(f1,f2,*algGlobClassic,true,false); + times(&tmsEnd); + cout <<((double) (tmsEnd.tms_utime - tmsStart.tms_utime))/sysconf(_SC_CLK_TCK) << "\t"; + // cerr << "#" << ali.getLocalOptimum() << "#"; + } + + + cout << endl; + + exit(EXIT_SUCCESS); + } + + Alignment ali(f1,f2,*alg); + RNA_Alignment ppfali; + ppfali.setStructureNames(f1->getName(),f2->getName()); + + + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + { + if(options.has(RNAforesterOptions::SmallInLarge)) + { + cout << "small-in-large optimal score: "; + } + else + { + if(options.has(RNAforesterOptions::LocalSimilarity)) + cout << "local optimal score: "; + else + cout << "global optimal score: "; + } + } + + if(options.has(RNAforesterOptions::SmallInLarge)) + { + cout << ali.getSILOptimum() << endl; + } + else + { + if(options.has(RNAforesterOptions::LocalSimilarity)) + { + cout << ali.getLocalOptimum() << endl; + } + else + { + cout << ali.getGlobalOptimum() << endl; + if(options.has(RNAforesterOptions::RelativeScore)) + cout << ali.getGlobalOptimumRelative() << endl; + } + } + + + if(!options.has(RNAforesterOptions::ShowOnlyScore)) + { + if(options.has(RNAforesterOptions::SmallInLarge)) + { + ali.getOptSILAlignment(ppfali,ybasepos); + cout << "starting at position: " << ybasepos << endl << endl; + } + else + { + if(options.has(RNAforesterOptions::LocalSimilarity)) + { + ali.resetOptLocalAlignment(suboptPercent); + ali.getOptLocalAlignment(ppfali,xbasepos,ybasepos); + cout << "starting at positions: " << xbasepos << "," << ybasepos << endl << endl; + } + else + ali.getOptGlobalAlignment(ppfali); + } + + // generate dot file + makeDotFileAli(ppfali,options); + + // print alignment + ppfali.getSequenceAlignments(seq1,seq2); + ppfali.getStructureAlignment(str1,true); + ppfali.getStructureAlignment(str2,false); + + if(options.has(RNAforesterOptions::FastaOutput)) + { + cout << ppfali.getStructureNameX() << endl; + cout << seq1 << endl; + cout << str1 << endl; + cout << ppfali.getStructureNameY() << endl; + cout << seq2 << endl; + cout << str2 << endl; + cout << endl; + } + else + RNAFuncs::printAli(ppfali.getStructureNameX(),ppfali.getStructureNameY(),seq1,seq2,str1,str2); + + + xlen=seq1.size(); + ylen=seq2.size(); + if(options.has(RNAforesterOptions::LocalSimilarity)) + { + xsubopts.push_back(pair(xbasepos,xlen)); + ysubopts.push_back(pair(ybasepos,ylen)); + } + +#ifdef HAVE_LIBG2 // This features require the g2 library + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + sprintf(s,"%d",count); + ppfali.squigglePlot(s,sqOptions); + } +#endif + + // suboptimal alignments + if(options.has(RNAforesterOptions::LocalSubopts)) + { + while(ali.nextLocalSuboptimum()) + { + count++; + cout << "local optimal score: "; + cout << ali.getLocalOptimum() << endl; + ali.getOptLocalAlignment(ppfali,xbasepos,ybasepos); + cout << "starting at positions: " << xbasepos << "," << ybasepos << endl << endl; + + // print alignment + ppfali.getSequenceAlignments(seq1,seq2); + ppfali.getStructureAlignment(str1,true); + ppfali.getStructureAlignment(str2,false); + RNAFuncs::printAli(ppfali.getStructureNameX(),ppfali.getStructureNameY(),seq1,seq2,str1,str2); + xlen=seq1.size(); + ylen=seq2.size(); + xsubopts.push_back(pair(xbasepos,xlen)); + ysubopts.push_back(pair(ybasepos,ylen)); + +#ifdef HAVE_LIBG2 // This features require the g2 library + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + sprintf(s,"%d",count); + ppfali.squigglePlot(s,sqOptions); + } +#endif + } + } + + } + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + // generate xml + if(options.has(RNAforesterOptions::GenerateXML)) + { + string filename; + + filename=options.generateFilename(RNAforesterOptions::GenerateXML,".xml", "ali.xml"); + ofstream s(filename.c_str()); + ppfali.generateXML(s); + } +#endif + +#ifdef HAVE_LIBG2 // This features require the g2 library + // generate squiggle plot + if(options.has(RNAforesterOptions::MakeSquigglePlot)) + { + f1->plot2d("x_str", xsubopts, sqOptions); + f2->plot2d("y_str", ysubopts, sqOptions); + } +#endif + + // clear input list + deque::const_iterator it; + for(it = inputListPW.begin(); it!=inputListPW.end(); it++) + delete *it; + inputListPW.clear(); + delete alg; +} + + +void editPairwise(list &inputListSZ,Score &score,RNAforesterOptions &options) +{ + // timeb t1,t2; + IntScoreSZAlgebraType *alg; + +// if(options.has(RNAforesterOptions::CalculateDistance)) + alg=new IntDistSZAlgebra(score); +// else +// alg=new IntSimiSZAlgebra(score); + + RNAForestSZ *f1=inputListSZ.front(); + RNAForestSZ *f2=inputListSZ.back(); + + // ftime(&t1); + Mapping mapping(f1,f2,*alg); + // ftime(&t2); + +// f1->printParameters("F1"); +// f2->printParameters("F2"); + + cout << "Global optimum: " << mapping.getGlobalOptimum() << endl; + // cout << "Calculation Time ms: " << (t2.time*1000+t2.millitm) - (t1.time*1000+t1.millitm) << endl; +} + + + +void alignPairwiseSimple(deque &inputListPW,Score &score,RNAforesterOptions &options) +{ + // timeb t1,t2; + IntScore_AlgebraType *alg; + +// if(options.has(RNAforesterOptions::CalculateDistance)) + alg=new IntDist_Algebra(score); +// else +// alg=new ScoreAlgebraSimple(score); + + RNAForest *f1=inputListPW.front(); + RNAForest *f2=inputListPW.back(); + + // ftime(&t1); + Alignment ali(f1,f2,*alg,false); + // ftime(&t2); + +// f1->printParameters("F1"); + //f2->printParameters("F2"); + + cout << "Global optimum: " << ali.getGlobalOptimum() << endl; + // cout << "Calculation Time ms: " << (t2.time*1000+t2.millitm) - (t1.time*1000+t1.millitm) << endl; +} + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/main.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/main.o new file mode 100755 index 0000000000000000000000000000000000000000..49733abbe03cea8580ca1fe7dbf74b24dadaeaf6 GIT binary patch literal 532488 zcmeFad3;nw)<0a;=?)%~Bs?t7UfjrZT7PDfX)qa@~8&@3M5-cXo 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Edge e joins a vertex in blossom */ +/* u to a linked vertex. */ + +#include "wmatch.h" + +void POINTER (int u, int v, int e) +{ int i, del; + +#ifdef DEBUG + printf("Pointer u,v,e=%d %d %d-%d\n",u,v,END[OPPEDGE(e)],END[e]); +#endif + + LINK[u] = -DUMMYEDGE; + NEXTVTX[LASTVTX[u]] = DUMMYVERTEX; + NEXTVTX[LASTVTX[v]] = DUMMYVERTEX; + + if (LASTVTX[u] != u) { + i = MATE[NEXTVTX[u]]; + del = -SLACK(i) / 2; + } + else del = LAST_D; + + i = u; + while (i != DUMMYVERTEX) { + Y[i] += del; + NEXT_D[i] += del; + i = NEXTVTX[i]; + } + if (LINK[v] < 0) { + LINK[v] = e; + NEXTPAIR[DUMMYEDGE] = DUMMYEDGE; + SCAN (v, DELTA); + return; + } + else { + LINK[v] = e; + return; + } +} + + +/* Scan each vertex in the blossom whose base is x */ + +void SCAN (int x, int del) +{ int u, del_e; + +#ifdef DEBUG + printf("Scan del=%d x=%d\n",del,x); +#endif + + newbase = BASE[x]; + stopscan = NEXTVTX[LASTVTX[x]]; + while (x != stopscan) { + Y[x] += del; + NEXT_D[x] = LAST_D; + pairpoint = DUMMYEDGE; + e = A[x]; + while (e != 0) { + neighbor = END[e]; + u = BASE[neighbor]; + if (LINK[u] < 0) { + if (LINK[BMATE (u)] < 0 || LASTVTX[u] != u) { + del_e = SLACK (e); + if (NEXT_D[neighbor] > del_e) { + NEXT_D[neighbor] = del_e; + NEXTEDGE[neighbor] = e; + } + } + } + else if (u != newbase) { + INSERT_PAIR(); + } + e = A[e]; + } + x = NEXTVTX[x]; + } + NEXTEDGE[newbase] = NEXTPAIR[DUMMYEDGE]; +} + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.h new file mode 100755 index 00000000..0b6bee38 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.h @@ -0,0 +1,124 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _PPFOREST_H_ +#define _PPFOREST_H_ + +#include +#include + +#include "algebra.h" +//#include "alignment.h" +#include "misc.h" +#include "ppforestbase.h" + +using namespace std; + +//template +//class Alignment; + +/** The template class PPForest is the basic class that is handled by the alignmnent + * algorithms of the RNAforester template library. The template parameter L is the + * datatype of the forest labels. + */ +template +class PPForest : public PPForestBase +{ + template + friend class Alignment; + + public: + typedef typename PPForestBase::size_type size_type; + +private: + /** internal function used by '<<' operator to print bracket notation of the forest*/ + void print(ostream &s,size_type node,bool brackets) const; + + /** Calculate maximal score of csf (i,j) for a certain Algebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ + template + R maxScore(const Algebra &alg, size_type i, size_type j) const; + /** Calculate maximal score of csf (i,j) for a certain RNAAlgebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ + template + R maxScore(const RNA_Algebra &alg, size_type i, size_type j) const; + + /** Function showLabel is used by print routines of PPForest */ +// virtual void showLabel(ostream &s,char c) const {s << c;}; + virtual void showLabel(ostream &s,L l) const {s << 'X';}; + + /** Function makeLabel is used by function buildForest */ +// virtual void makeLabel(char &a,char c) {a=c;}; + + void makeLabel(L &a,char c) {}; + + +protected: + L *m_lb; + + void initialize(size_type size); + +public: + typedef L label_type; + + /** Default Constructor */ + PPForest() : PPForestBase(), m_lb(NULL) {}; + /** Construct a PPForest with 'size' nodes */ + PPForest(size_type size); + /** Copy constructor */ + PPForest(const PPForest &ppf); + /** Read PPForest from binary file */ + PPForest(istream &s); + + virtual ~PPForest(); + + /** returns label of node i */ + inline L label(size_type i) const {return m_lb[i];}; + + /** Calculate maximal score of a forest alignment against itself for a certain Algebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ + template + inline R maxScore(const Algebra &alg) const + { + return maxScore(alg,0,getMaxLength(0)); + } + + /** Calculate maximal score of a forest alignment against itself for a certain RNA_Algebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ + template + inline R maxScore(const RNA_Algebra &alg) const + { + return maxScore(alg,0,getMaxLength(0)); + } + + /** Print forest in GraphViz format */ + void printDot(ostream &s) const; + + /** Save forest to binary file */ + void save(ostream &s) const; +}; + +/** Stream output operator for PPForest */ +template +ostream& operator<< (ostream &s, PPForest &ppf); + +#endif + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.t.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.t.cpp new file mode 100755 index 00000000..dfde8be2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforest.t.cpp @@ -0,0 +1,226 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _PPFOREST_T_CPP_ +#define _PPFOREST_T_CPP_ + +#include "misc.h" +#include "ppforest.h" + +/* ****************************************** */ +/* Constructor and Destruktor functions */ +/* ****************************************** */ + +template +PPForest::PPForest(size_type size): PPForestBase(size) +{ + m_lb=new L[size]; +} + +template +PPForest::PPForest(const PPForest &ppf) : PPForestBase(ppf) +{ + m_lb=new L[ppf.size()]; + + // copy labels + for(size_type i=0;i +PPForest::PPForest(istream &s) +{ + /* + // read ppforest from file + + // first of all save the size + s.read(static_cast(m_size),sizeof(PPForestBase::size_type)); + + // initialize structures + ::PPForestBase(m_size); + m_lb=new L[ppf.size()]; + + // save the arrays + s.read(static_cast(m_lb),sizeof(label_type)*m_size); + s.read(static_cast(m_rb),sizeof(PPForestBase::size_type)*m_size); + s.read(static_cast(m_noc),sizeof(PPForestBase::size_type)*m_size); + s.read(static_cast(m_sumUpCSF),sizeof(PPForestBase::size_type)*m_size); + s.read(static_cast(m_rmb),sizeof(PPForestBase::size_type)*m_size); + */ +} + +template +PPForest::~PPForest() +{ + DELETE_ARRAY(m_lb); +} + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +template +void PPForest::print(ostream &s,size_type node,bool brackets) const +{ + if(brackets) + s << "("; + + s << "{" << node << "}"; + showLabel(s,m_lb[node]); + if(m_noc[node]) + print(s,node+1,true); + if(m_rb[node]) + print(s,m_rb[node],false); + + if(brackets) + s << ")"; +} + +/** Calculate maximal score of csf (i,j) for a certain Algebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ +template +template +R PPForest::maxScore(const Algebra &alg, size_type i, size_type j) const +{ + R down, over; + + if(j==0) + return 0; + + if(isLeave(i)) + { + over=maxScore(alg,rb(i),j-1); + return alg.replace(label(i),0,label(i),over); + } + else + { + down=maxScore(alg,i+1,noc(i)); + over=maxScore(alg,rb(i),j-1); + return alg.replace(label(i),down,label(i),over); + } +} + +/** Calculate maximal score of csf (i,j) for a certain RNA_Algebra. + * It is assumed that a perfect match of the forest obtains the best + * possible score. + */ +template +template +R PPForest::maxScore(const RNA_Algebra &alg, Uint i, Uint j) const +{ + R down, over; + + if(j==0) + return 0; + + if(isLeave(i)) + { + over=maxScore(alg,rb(i),j-1); + return alg.replace(label(i),0,label(i),over); + } + else + { + down=maxScore(alg,i+1+1,noc(i)-2); + over=maxScore(alg,rb(i),j-1); + return alg.replacepair(label(i+1),label(i+1),down,label(getRightmostBrotherIndex(i+1)),label(getRightmostBrotherIndex(i+1)),over); + } +} + +/* ****************************************** */ +/* Protected function */ +/* ****************************************** */ + +template +void PPForest::initialize(size_type size) +{ + PPForestBase::initialize(size); + m_lb=new L[size]; +} + +/* ****************************************** */ +/* Public functions */ +/* ****************************************** */ + + +template +void PPForest::printDot(ostream &s) const +{ + size_type i,h; + + s << "digraph forest" << endl << "{" << endl; + + // edges + for(i=0;i {"; + h=i+1; + for(Uint r=0;r +void PPForest::save(ostream &s) const +{ + /* + // save the pforest to stream in binary format + + // first of all save the size + s.write(reinterpret_cast(&m_size),sizeof(PPForestBase::size_type)); + // save the arrays + s.write(reinterpret_cast(m_lb),sizeof(label_type)*m_size); + s.write(reinterpret_cast(m_rb),sizeof(PPForestBase::size_type)*m_size); + s.write(reinterpret_cast(m_noc),sizeof(PPForestBase::size_type)*m_size); + s.write(reinterpret_cast(m_sumUpCSF),sizeof(PPForestBase::size_type)*m_size); + s.write(reinterpret_cast(m_rmb),sizeof(PPForestBase::size_type)*m_size); + */ +} + +template +ostream& operator<< (ostream &s, PPForest &ppf) +{ + ppf.print(s,0,true); + return s; +} + +#endif + + + + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestali.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestali.h new file mode 100755 index 00000000..db082539 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestali.h @@ -0,0 +1,52 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _PPFORESTALI_H_ +#define _PPFORESTALI_H_ + +//#include "alignment.h" +#include "ppforest.h" + +//template +//class Alignment; + +/** PPForestAli is the Base class of forest Alignemnts. + * The pure virtual functions must be implemented when + * inherited to allow the construction of alignments. + */ + +template +class PPForestAli : public PPForest +{ +public: + typedef typename PPForest::size_type size_type; + + //private: +public: + /** @name Interface functions for alignment construction */ + //@{ + + virtual void makeRepLabel(size_type node,L a, L b) = 0; + virtual void makeDelLabel(size_type node,L a) = 0; + virtual void makeInsLabel(size_type node,L b) = 0; + + //@} + +public: + PPForestAli() : PPForest(){}; + PPForestAli(size_type size) : PPForest(size) {}; + + // virtual ~PPForestAli(){}; +}; + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestbase.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestbase.cpp new file mode 100755 index 00000000..7a7e9a4c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestbase.cpp @@ -0,0 +1,202 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#include "misc.h" +#include "ppforestbase.h" +#include "debug.h" + +#include +#include +#include + +#include "misc.t.cpp" + +/* ****************************************** */ +/* Constructor and Destructor functions */ +/* ****************************************** */ + +PPForestBase::PPForestBase(size_type size) +{ + initialize(size); +}; + +PPForestBase::PPForestBase(const PPForestBase &ppfBase) +{ + initialize(ppfBase.size()); + + memcpy(m_rb,ppfBase.m_rb,sizeof(size_type)*m_size); + memcpy(m_noc,ppfBase.m_noc,sizeof(size_type)*m_size); + memcpy(m_sumUpCSF,ppfBase.m_sumUpCSF,sizeof(size_type)*(m_size+1)); + memcpy(m_rmb,ppfBase.m_rmb,sizeof(size_type)*m_size); + + m_isSumUpCSFValid=ppfBase.m_isSumUpCSFValid; + m_isRMBValid=ppfBase.m_isRMBValid; +} + +PPForestBase::~PPForestBase() +{ + DELETE_ARRAY(m_rb); + DELETE_ARRAY(m_noc); + DELETE_ARRAY(m_sumUpCSF); + DELETE_ARRAY(m_rmb); +}; + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +PPForestBase::size_type PPForestBase::countLeaves(size_type i) const +{ + size_type numLeaves=0; + + for(size_type k=0;k=0;i--) + { + if(m_rb[i]) + m_rmb[i]=m_rmb[m_rb[i]]; + else + m_rmb[i]=i; + } + + m_isRMBValid=true; +} + +void PPForestBase::initialize(size_type size) +{ + m_size=size; + m_rb=new size_type[size]; + m_noc=new size_type[size]; + m_sumUpCSF=new size_type[size+1]; + m_rmb=new size_type[size]; + + m_isSumUpCSFValid=false; + m_isRMBValid=false; +} + +/* ****************************************** */ +/* Public functions */ +/* ****************************************** */ + +PPForestBase::size_type PPForestBase::rb(size_type i, size_type k) const +{ + if(k==0) + return i; + else + return rb(rb(i),k-1); +} + +PPForestBase::size_type PPForestBase::maxDegree() const +{ + size_type degree=0; + + for(size_type i=0;i +*/ + +#ifndef _PPFOREST_BASE_H +#define _PPFOREST_BASE_H + +#include +#include + +#include "misc.h" +#include "types.h" + +using namespace std; + +/** PPForestBase is the base class of the template class PPForest. + * To reduce the size of compiled programs functions and variables that are + * independent of the labelling are implemented in this class. + */ +class PPForestBase +{ + //template + //friend class Alignment; + + public: + typedef Uint size_type; + + private: + bool m_isSumUpCSFValid; + bool m_isRMBValid; + + size_type getNumRightBrothers(size_type i) const; + size_type countLeaves(size_type i,size_type k) const; + +protected: + size_type m_size; /**< size is the number of nodes of a tree */ + size_type *m_rb; /**< m_rb[i] stores the preorder index of the rightbrother node of the ith node, or 0 if there is none. */ + size_type *m_noc; /**< m_noc[i] stores the number of children of the ith node */ + size_type *m_sumUpCSF; /**< m_sumUpCSF[i] stores the sum of non empty closed subforests of nodes k=i && i2<=max_node) + return false; + + if(rb(i2,j2-1)>=i && rb(i2,j2-1)<=max_node) + return false; + + // (i,j) included in (i2,j2) + max_node=getRightmostBrotherIndex(i2); + if(noc(max_node)) + max_node=getRightmostBrotherIndex(max_node+1); + + + if(i>=i2 && i<=max_node) + return false; + + if(rb(i,j-1)>=i2 && rb(i,j-1)<=max_node) + return false; + + return true; + } +}; + +#endif + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestbase.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestbase.o new file mode 100755 index 0000000000000000000000000000000000000000..f19de9d2b9ae673d2303102e4723c4f00329118c GIT binary patch literal 72544 zcmeFad3aUT)d#%KJ?DlH5^_TZ0f}B9pn*V0NVo}OAcR2%17SwEWVj*0Oy(v8)FPHT z#FUEKT8GwZ)ecsDou^vsJhfG;);hEnTWuY17VCie{np-VpL@=o!1sB-@2`)CoORAx zYfo#hz4qE`?{n@MHA@#5h9UGnLzp7+B*eY{P?RzWju*#@QJPi4)%|Y_EK9E&SnV6w zl=@EUzJco069&@HJ?q)tgB$xF-}DgZb$bq2AcAt%{k^LOs?z~x4pjR93I?ik0MgcN 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/ppforestsz.h @@ -0,0 +1,69 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _PPFORESTSZ_H +#define _PPFORESTSZ_H + +#include +#include + +#include "misc.h" +#include "types.h" + +using namespace std; + +template +class PPForestSZ +{ + protected: + Uint m_size; + Uint *m_lml; // postorder index of leftmost leaf descandant of the subtree rootet at T[i] + L *m_lb; // labels of nodes in postorder + bool *m_keyroot; // is node a keyroot + + void calcKeyroots(); + + public: + typedef Uint size_type; + typedef L label_type; + + PPForestSZ() : m_size(0), m_lml(NULL), m_lb(NULL),m_keyroot(NULL) {}; + PPForestSZ(Uint nrOfNodes); + PPForestSZ(const PPForestSZ &ppf); + ~PPForestSZ(); + + inline size_type size() const {return m_size;}; + inline Uint lml(Ulong i) const {return m_lml[i];}; + inline L label(Ulong i) const {return m_lb[i];}; + inline bool keyroot(Ulong i) const {return m_keyroot[i];}; + + Uint numKeyroots() const + { + Uint count=0; + for(Uint i=0;i +*/ + +#ifndef _PPFORESTSZ_T_CPP_ +#define _PPFORESTSZ_T_CPP_ + +#include + +#include "misc.h" +#include "ppforestsz.h" + + +// PPForest + +template +PPForestSZ::PPForestSZ(Uint nrOfNodes) +: m_size(nrOfNodes) +{ + m_lml=new Uint[nrOfNodes]; + m_lb=new L[nrOfNodes]; + m_keyroot=new bool[nrOfNodes]; +} + +template +PPForestSZ::PPForestSZ(const PPForestSZ &ppf) +{ + m_size=ppf.size(); + + m_lml=new Uint[ppf.size()]; + m_lb=new L[ppf.size()]; + m_keyroot=new bool[ppf.size()]; + + memcpy(m_lml,ppf.m_lml,sizeof(Uint)*m_size); + memcpy(m_keyroot,ppf.m_keyroot,sizeof(bool)*m_size); + + for(Uint i=0;i +PPForestSZ::~PPForestSZ() +{ + DELETE_ARRAY(m_lml); + DELETE_ARRAY(m_lb); + DELETE_ARRAY(m_keyroot); +} + +template +void PPForestSZ::calcKeyroots() +{ + std::map keyrootMap; + + for(Uint i=0;i::const_iterator it; + for(it=keyrootMap.begin();it!=keyrootMap.end();it++) + { + m_keyroot[it->second]=true; + } + +} + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.cpp new file mode 100755 index 00000000..ddeb9e9e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.cpp @@ -0,0 +1,343 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#include +#include + +#include "alignment.h" +#include "progressive_align.h" + +#include "alignment.t.cpp" + +using namespace std; + +// !!! this operator is defined as > !!! +bool operator < (pair &l, pair &r) +{ + if(l.second->getNumStructures() < r.second->getNumStructures()) + return false; + else + return true; +} + +void progressiveAlign(deque &inputList, deque > &resultList, const DoubleScoreProfileAlgebraType *alg,const RNAforesterOptions &options) +{ + RNAProfileAliMapType inputMapProfile; + deque alignList; + RNAProfileAliMapType::iterator it,it2; + long x,y,bestx,besty; // keys of stuctures in inputMapProfile + RNAProfileAlignment *ppfx=NULL,*ppfy=NULL,*ppf=NULL; + int level=1; + double bestScore,threshold,cutoff; + string clusterfilename; + ofstream s; + Matrix *score_mtrx; + bool local; + + local=options.has(RNAforesterOptions::LocalSimilarity); + + cout << "*** Calculation ***" << endl << endl; + + // create inputMapProfile to access a profile by an index value + deque::const_iterator inpIt; + long i=1; + for(inpIt=inputList.begin();inpIt!=inputList.end();inpIt++) + { + inputMapProfile[i]=*inpIt; + i++; + } + inputList.clear(); + + // create matrix for all against all comparison + bestScore=alg->worst_score(); + score_mtrx=new Matrix(inputMapProfile.size(),inputMapProfile.size()); + + // set threshold for the clustering algorithm + if(options.has(RNAforesterOptions::CalculateDistance)) + options.get(RNAforesterOptions::ClusterThreshold,threshold,20.0); + else + options.get(RNAforesterOptions::ClusterThreshold,threshold,0.7); + cout << "clustering threshold is: " << threshold << endl; + + // set cutoff value for clustering + if(options.has(RNAforesterOptions::CalculateDistance)) + options.get(RNAforesterOptions::ClusterJoinCutoff,cutoff,100.0); + else + options.get(RNAforesterOptions::ClusterJoinCutoff,cutoff,0.0); + cout << "join clusters cutoff is: " << cutoff << endl << endl; + + // generate dot file + clusterfilename=options.generateFilename(RNAforesterOptions::Help,"_cluster.dot", "cluster.dot"); // use Help as dummy + s.open(clusterfilename.c_str()); + s << "digraph forest" << endl << "{" << endl; + + // generate nodes for the input forests + for(it=inputMapProfile.begin();it!=inputMapProfile.end();it++) + { + ppf=it->second; + + s << "\"" << ppf->getName() << "\"" << "[label=\"" << ppf->getName() << "\"]" << endl; + s << "\"" << ppf->getName() << "\"" << "[label=\"" << ppf->getName() << "\"]" << endl; + } + + + // compute all pairwise distances + // !! NOTE !! iterating through the map is ordered by key number + // as i only calculate a triangle matrix this is a prerequisite + cout << "Computing all pairwise similarities" << endl; + for(it=inputMapProfile.begin();it!=inputMapProfile.end();it++) + { + x=it->first; + ppfx=it->second; + for(it2=inputMapProfile.begin();it2->firstfirst;it2++) + { + y=it2->first; + ppfy=it2->second; + + Alignment ali(ppfx,ppfy,*alg,local); + if(local) + score_mtrx->setAt(x-1,y-1,ali.getLocalOptimum()); + else + score_mtrx->setAt(x-1,y-1,ali.getGlobalOptimumRelative()); + + cout << x << "," << y << ": " << score_mtrx->getAt(x-1,y-1) << endl; + + WATCH(DBG_MULTIPLE,"progressiveAlign",x); + WATCH(DBG_MULTIPLE,"progressiveAlign",y); + WATCH(DBG_MULTIPLE,"progressiveAlign",ali.getGlobalOptimumRelative()); + } + } + cout << endl; + + while(inputMapProfile.size()>1) + { + // find the best score of all pairwise alignments + bestScore=alg->worst_score(); + for(it=inputMapProfile.begin();it!=inputMapProfile.end();it++) + { + x=it->first; + for(it2=inputMapProfile.begin();it2->first < it->first;it2++) + { + double old_bestScore=bestScore; + + y=it2->first; + WATCH(DBG_MULTIPLE,"progressiveAlign",x); + WATCH(DBG_MULTIPLE,"progressiveAlign",y); + WATCH(DBG_MULTIPLE,"progressiveAlign",score_mtrx->getAt(x-1,y-1)); + + WATCH(DBG_MULTIPLE,"progressiveAlign",bestScore); + bestScore=alg->choice(bestScore,score_mtrx->getAt(x-1,y-1)); + + if(bestScore!=old_bestScore) + { + bestx=it->first; + besty=it2->first; + old_bestScore=bestScore; + } + } + } + + WATCH(DBG_MULTIPLE,"progressiveAlign",bestScore); + cout << "joining alignments:" << endl; + + // if threshold is set generate a list of best pairs within threshold + if(alg->choice(bestScore,threshold)!= threshold) + { + Graph graph; + int *mate; + int maximize; + + graph=makePairsGraph(inputMapProfile,alg,score_mtrx,threshold); + if(options.has(RNAforesterOptions::CalculateDistance)) + maximize=0; + else + maximize=1; + + mate = Weighted_Match(graph,1,maximize); + for(x=1;x<=score_mtrx->xDim();x++) // !! begins at 1 !! + { + if(x1) + { + string aliName; + + x=alignList.front().first; + ppfx=alignList.front().second; + alignList.erase(alignList.begin()); + y=alignList.front().first; + ppfy=alignList.front().second; + alignList.erase(alignList.begin()); + + // compute alignment again + Alignment bestali(ppfx,ppfy,*alg,local); + if(local) + bestScore=bestali.getLocalOptimum(); + else + bestScore=bestali.getGlobalOptimumRelative(); + + // test, if score is worse than the cutoff value + if(alg->choice(bestScore,cutoff)== cutoff) + { + // copy involved forests to the result list + cout << x << "," << y << ": alignment is below cutoff." << endl; + if(ppfx->getNumStructures()>1) + resultList.push_back(make_pair(ppfx->maxScore(*alg),ppfx)); + if(ppfy->getNumStructures()>1) + resultList.push_back(make_pair(ppfy->maxScore(*alg),ppfy)); + } + else + { + // calculate optimal alignment and add it to inputMapProfile + + ppf=new RNAProfileAlignment(ppfx->getNumStructures(),ppfy->getNumStructures()); + + if(local) + { + Uint xbasepos,ybasepos; + bestali.getOptLocalAlignment(*ppf,xbasepos,ybasepos); + } + else + { + bestali.getOptGlobalAlignment(*ppf); + } + + ppf->addStrNames(ppfx->getStrNames()); + ppf->addStrNames(ppfy->getStrNames()); + aliName=ppfx->getName() + "." +ppfy->getName(); + ppf->setName(aliName); + + // for debug purposes + //string dotfilename; + //dotfilename=ppf->getName() + string(".dot"); + // ofstream s("test.dot"); + // ppf->printDot(s); + + // generate nodes in cluster file (dot format) + s << "\"" << ppf->getName() << "\"" << "[shape=\"diamond\" label=\"" << bestScore << "\"]" << endl; + s << "\"" << ppf->getName() << "\"" << "-> {\"" << ppfx->getName() << "\" \"" << ppfy->getName() << "\"}"; + + cout << x << "," << y << ": " << bestScore << " -> " << min(x,y) << endl; + + delete ppfx; + delete ppfy; + + // calculate distance to all forests in the list + cout << "Calculate similarities to other clusters" << endl; + ppfx=ppf; + // x remains x !! + for(it=inputMapProfile.begin();it!=inputMapProfile.end();it++) + { + y=it->first; + ppfy=it->second; + Alignment ali(ppfx,ppfy,*alg,local); + if(local) + { + score_mtrx->setAt(min(x-1,y-1),max(x-1,y-1),ali.getLocalOptimum()); // min - max = fill the upper triangle + cout << min(x,y) << "," << max(x,y) << ": " << ali.getLocalOptimum() << endl; + } + else + { + score_mtrx->setAt(min(x-1,y-1),max(x-1,y-1),ali.getGlobalOptimumRelative()); // min - max = fill the upper triangle + cout << min(x,y) << "," << max(x,y) << ": " << ali.getGlobalOptimumRelative() << endl; + } + } + cout << endl; + + // ... and append it to the list + inputMapProfile.insert(make_pair(x,ppf)); + } + } + + level++; + } + + assert(inputMapProfile.size()<2); + + // copy last profile to resultList + if(inputMapProfile.size()==1) + { + ppf=inputMapProfile.begin()->second; + resultList.push_back(make_pair(ppf->maxScore(*alg),ppf)); + inputMapProfile.clear(); + } + + // end of dot file + s << "}" << endl; + + // sort result list + // std::sort(resultList.begin(),resultList.end()); + + + delete score_mtrx; +} + +Graph makePairsGraph(const RNAProfileAliMapType &inputMapProfile, const DoubleScoreProfileAlgebraType *alg, const Matrix *score_mtrx, double threshold) +{ + Graph graph; + RNAProfileAliMapType::const_iterator it,it2; + RNAProfileAlignment *ppfx=NULL,*ppfy=NULL; + + graph = NewGraph(score_mtrx->xDim()); + + for(int i=0;ixDim();i++) + { + Xcoord(graph,i+1) = 0; + Ycoord(graph,i+1) = 0; + } + + for(it=inputMapProfile.begin();it!=inputMapProfile.end();it++) + { + ppfx=it->second; + for(it2=inputMapProfile.begin();it2->firstfirst;it2++) + { + double score; + ppfy=it2->second; + + score=score_mtrx->getAt(it->first-1,it2->first-1); + if(alg->choice(score,threshold) != threshold) // is it better than the threshold ? + { + AddEdge (graph,it->first,it2->first,(int)(score*100.0)); + } + } + } + + + WriteGraph (graph,"test.out"); + return graph; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.h new file mode 100755 index 00000000..16485194 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.h @@ -0,0 +1,32 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#include "graphtypes.h" +#include "matrix.h" +#include "rnaforester_options.h" +#include "rna_profile_alignment.h" +#include "wmatch.h" + +/* ****************************************** */ +/* Definitions and typedefs */ +/* ****************************************** */ + +typedef map RNAProfileAliMapType; +typedef pair RNAProfileAliKeyPairType; + +/* ****************************************** */ +/* Function prototypes */ +/* ****************************************** */ + +void progressiveAlign(deque &inputList, deque > &resultList, const DoubleScoreProfileAlgebraType *alg,const RNAforesterOptions &options); +Graph makePairsGraph(const RNAProfileAliMapType &inputListProfile, const DoubleScoreProfileAlgebraType *alg, const Matrix *score_mtrx, double threshold); diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/progressive_align.o new file mode 100755 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zu{ru<00v@j?1zIe7(;M0j>kzj2g5M}BQXYJF%IJ~0e9nmJdBB$gvpqK_b?UHFdaYQ dSG2Nm{Lv9}qB9mp7j#7r^u*fejXvm${|7)RXoLU& literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/readgraph.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/readgraph.c new file mode 100755 index 00000000..772a7309 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/readgraph.c @@ -0,0 +1,129 @@ +/* set up data structures for weighted match */ + +/* to add a new type, add new case in SetUp() and a Set_X() routine */ + +#include +#include + +#include "wmatch.h" + +void SetUp (void* gptr, int type) +{ int i,allocsize; + Graph g=NULL; + EuclidGraph xy=NULL; + MatrixGraph matg=NULL; + + if (type==1) { + g = (Graph) gptr; + U = Degree(g,0); + V = NumEdges(g); + } + else if (type==2) { + xy = (EuclidGraph) gptr; + U = xy[0][0]; + V = U*(U-1)/2; + } + else if (type==3) { + matg = (MatrixGraph) gptr; + U = matg[0]; + V = U*(U-1)/2; + } + + allocsize = (U+2*V+2)*sizeof(int); + A = (int *) malloc(allocsize); + END = (int *) malloc(allocsize); + WEIGHT = (int *) malloc(allocsize); + for (i=0; i adj_node) + break; + u = v; + v = A[v]; + } + A[u] = currentedge; + A[currentedge] = v; + } + u = adj_node; + v = A[u]; + while (v != 0) { + u = v; + v = A[v]; + } + A[u] = currentedge - 1; + currentedge += 2; + } + edge = NextEdge(edge); + } + } +} + +/* set up from Euclidean graph */ + +void SetEuclid(EuclidGraph graph) +{ int i,j,currentedge; + + currentedge = U+2; + + for (i=U; i>=1; --i) + for (j = i-1; j >= 1; --j) { + WEIGHT[currentedge-1] = WEIGHT[currentedge] + = 2*eucdist2(graph,i,j); + END[currentedge-1] = i; + END[currentedge] = j; + A[currentedge] = A[i]; + A[i] = currentedge; + A[currentedge-1] = A[j]; + A[j] = currentedge-1; + currentedge += 2; + } +} + +void SetMatrix(MatrixGraph graph) +{ int i,j,currentedge; + + currentedge = U+2; + + for (i=U; i>=1; --i) + for (j = i-1; j >= 1; --j) { + WEIGHT[currentedge-1] = WEIGHT[currentedge] + = 2*graph[j*U+i]; + END[currentedge-1] = i; + END[currentedge] = j; + A[currentedge] = A[i]; + A[i] = currentedge; + A[currentedge-1] = A[j]; + A[j] = currentedge-1; + currentedge += 2; + } +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.cpp new file mode 100755 index 00000000..108d82e5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.cpp @@ -0,0 +1,89 @@ +#include "rna_algebra.h" + +Score::Score(RNAforesterOptions &options) +{ + m_isLocal=options.has(RNAforesterOptions::LocalSimilarity); + m_isRIBOSUM=options.has(RNAforesterOptions::RIBOSUMScore); + + // distance or similarity ? + if(options.has(RNAforesterOptions::CalculateDistance)) + { + m_isDistance=true; + m_bp_rep_score = 0; + m_bp_del_score = 3; + m_b_match_score = 0; + m_b_rep_score =1; + m_b_del_score =2; + } + else + { + m_isDistance=false; + + if(options.has(RNAforesterOptions::RIBOSUMScore)) + { + m_bp_del_score=-100; + m_b_del_score=-200; + } + else + { + m_bp_rep_score = 10; + m_bp_del_score =-5; + m_b_match_score = 1; + m_b_rep_score = 0; + m_b_del_score =-10; + } + } + + // read scores + options.get(RNAforesterOptions::BpRepScore,m_bp_rep_score,m_bp_rep_score); + options.get(RNAforesterOptions::BpDelScore,m_bp_del_score,m_bp_del_score); + options.get(RNAforesterOptions::BMatchScore,m_b_match_score,m_b_match_score); + options.get(RNAforesterOptions::BRepScore,m_b_rep_score,m_b_rep_score); + options.get(RNAforesterOptions::BDelScore,m_b_del_score,m_b_del_score); +} + +Score::Score(const Score &s) +{ + // copy scores + m_isDistance = s.m_isDistance; + m_isLocal = s.m_isLocal; + m_bp_rep_score = s.m_bp_rep_score; + m_bp_del_score = s.m_bp_del_score; + m_b_match_score = s.m_b_match_score; + m_b_rep_score = s.m_b_rep_score; + m_b_del_score = s.m_b_del_score; +} + +void Score::print() +{ + // show score parameters + cout << "*** Scoring parameters ***" << endl << endl; + + cout << "Scoring type: "; + if(m_isDistance) + cout << "distance" << endl; + else + { + if(m_isLocal) + cout << "local "; + + cout << "similarity" << endl; + } + + cout << "Scoring parameters:" << endl; + + if(m_isRIBOSUM) + { + cout << "RIBOSUM85-60 Scoring matrix" << endl; + cout << "pd: " << m_bp_del_score << endl; + cout << "bd: " << m_b_del_score << endl << endl; + } + else + { + cout << "pm: " << m_bp_rep_score << endl; + cout << "pd: " << m_bp_del_score << endl; + cout << "bm: " << m_b_match_score << endl; + cout << "br: " << m_b_rep_score << endl; + cout << "bd: " << m_b_del_score << endl << endl; + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.h new file mode 100755 index 00000000..ae5bc07c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.h @@ -0,0 +1,636 @@ +#ifndef _RNA_ALGEBRA_H_ +#define _RNA_ALGEBRA_H_ + +#include +#include + +#include "algebra.h" +#include "debug.h" +#include "misc.h" +#include "rna_alphabet.h" +#include "rnaforester_options.h" + +/* ****************************************** */ +/* Definitions and typedefs */ +/* ****************************************** */ + +const double DBL_NEG = -100000000.0; // the values from limits.h caused problems.. +const double DBL_POS = 100000000.0; + +typedef Algebra DoubleScoreProfileAlgebraType; +typedef Algebra IntScore_AlgebraType; +typedef RNA_Algebra IntScoreRNA_AlgebraType; +typedef SZAlgebra IntScoreSZAlgebraType; + +/* ****************************************** */ +/* Class Score */ +/* ****************************************** */ + +/** Class Score reads scoring parameters from RNAforester command line. */ +class Score +{ + private: + bool m_isDistance; + bool m_isLocal; + bool m_isRIBOSUM; + + public: + int m_bp_rep_score; + int m_bp_del_score; + int m_b_match_score; + int m_b_rep_score; + int m_b_del_score; + + Score(RNAforesterOptions &options); + Score(const Score &s); + void print(); +}; + +/* ****************************************** */ +/* RNA Algebra Classes */ +/* ****************************************** */ + +/** Similarity algebra for RNA forests */ +class IntSimiRNA_Algebra : public IntScoreRNA_AlgebraType +{ + private: + Score m_s; + + public: + int empty() const {return 0;}; + int replacepair(RNA_Alphabet la, RNA_Alphabet lb, int down, RNA_Alphabet ra, RNA_Alphabet rb, int over) const + { + return m_s.m_bp_rep_score+down+over; + }; + + int replace(RNA_Alphabet a,int down, RNA_Alphabet b, int over) const + { + if(a==ALPHA_BASEPAIR && b == ALPHA_BASEPAIR) + return m_s.m_bp_rep_score+down+over; + else + { + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MIN/4; + else + { + if(a==b) + return m_s.m_b_match_score+down+over; + else + return m_s.m_b_rep_score+down+over; + } + } + }; + + int del(RNA_Alphabet a,int down, int over) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int insert(int down,RNA_Alphabet b,int over) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int choice(int a, int b) const + { + return max(a,b); + }; + + int worst_score() const + { + return INT_MIN; + }; + + IntSimiRNA_Algebra(const Score &s) + : m_s(s) {}; +}; + +/** Distance algebra for RNA forests */ +class IntDistRNA_Algebra : public IntScoreRNA_AlgebraType +{ + private: + Score m_s; + + public: + int empty() const {return 0;}; + int replacepair(RNA_Alphabet la, RNA_Alphabet lb, int down, RNA_Alphabet ra, RNA_Alphabet rb, int over) const + { + return m_s.m_bp_rep_score+down+over; + }; + + int replace(RNA_Alphabet a,int down, RNA_Alphabet b, int over) const + { + if(a==ALPHA_BASEPAIR && b == ALPHA_BASEPAIR) + return m_s.m_bp_rep_score+down+over; + else + { + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MAX/4; + else + { + if(a==b) + return m_s.m_b_match_score+down+over; + else + return m_s.m_b_rep_score+down+over; + } + } + }; + + int del(RNA_Alphabet a,int down,int over) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int insert(int down,RNA_Alphabet b,int over) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int choice(int a, int b) const + { + return min(a,b); + }; + + int worst_score() const + { + return INT_MAX; + }; + + IntDistRNA_Algebra(const Score &s) + : m_s(s) {}; +}; + +/** RIBOSUM85-60 matrix published in RSEARCH: Finding homologs of single structured RNA sequences + * R. Klein and S. Eddy, BMC Bioinformatics 2003 Vol.4 + */ +class RIBOSUM8560 : public IntScoreRNA_AlgebraType +{ + private: + Score m_s; + int m_baseSubstMtrx[4][4]; + int m_basepairSubstMtrx[4][4][4][4]; + + public: + int empty() const {return 0;}; + int replacepair(RNA_Alphabet la, RNA_Alphabet lb, int down, RNA_Alphabet ra, RNA_Alphabet rb, int over) const + { + int i,j,k,l; + i=alpha2RNA_Alpha(la); + j=alpha2RNA_Alpha(ra); + k=alpha2RNA_Alpha(lb); + l=alpha2RNA_Alpha(rb); + + return m_basepairSubstMtrx[i][j][k][l]+down+over; + }; + + int replace(RNA_Alphabet a,int down, RNA_Alphabet b, int over) const + { + assert(!(a==ALPHA_BASEPAIR && b==ALPHA_BASEPAIR)); + + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MIN/4; + else + { + int i,j; + i=alpha2RNA_Alpha(a); + j=alpha2RNA_Alpha(b); + + return m_baseSubstMtrx[i][j]+down+over; + } + }; + + int del(RNA_Alphabet a,int down, int over) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int insert(int down,RNA_Alphabet b,int over) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int choice(int a, int b) const + { + return max(a,b); + }; + + int worst_score() const + { + return INT_MIN; + }; + + RIBOSUM8560(const Score &s) + : m_s(s) + { + int i,j,k,l; + + // set substitution matrices + + // base replacement + m_baseSubstMtrx[ALPHA_PRO_BASE_A][ALPHA_PRO_BASE_A]=222; + m_baseSubstMtrx[ALPHA_PRO_BASE_A][ALPHA_PRO_BASE_C]=-186; + m_baseSubstMtrx[ALPHA_PRO_BASE_A][ALPHA_PRO_BASE_G]=-146; + m_baseSubstMtrx[ALPHA_PRO_BASE_A][ALPHA_PRO_BASE_U]=-139; + + m_baseSubstMtrx[ALPHA_PRO_BASE_C][ALPHA_PRO_BASE_C]=116; + m_baseSubstMtrx[ALPHA_PRO_BASE_C][ALPHA_PRO_BASE_G]=-248; + m_baseSubstMtrx[ALPHA_PRO_BASE_C][ALPHA_PRO_BASE_U]=-105; + + m_baseSubstMtrx[ALPHA_PRO_BASE_G][ALPHA_PRO_BASE_G]=103; + m_baseSubstMtrx[ALPHA_PRO_BASE_G][ALPHA_PRO_BASE_U]=-174; + + m_baseSubstMtrx[ALPHA_PRO_BASE_U][ALPHA_PRO_BASE_U]=165; + + // copy triangle + for(i=0;i<=ALPHA_PRO_BASE_U;i++) + for(j=0;j0 && b.p[ALPHA_PRO_BASEPAIR]>0) + { + // pair replacement + return a.p[ALPHA_PRO_BASEPAIR]*b.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_rep_score + + down+over; + } + else + { + if(a.p[ALPHA_PRO_BASE]>0 && b.p[ALPHA_PRO_BASE]>0) + { + double s=0; + + // base replacement + for(int i=ALPHA_PRO_BASE_A;i<=ALPHA_PRO_BASE_U;i++) + for(int j=ALPHA_PRO_BASE_A;j<=ALPHA_PRO_BASE_U;j++) + s+= i==j ? a.p[i]*b.p[j]*m_s.m_b_match_score : a.p[i]*b.p[j]*m_s.m_b_rep_score; + + if(s==0) // no sequence information + s=a.p[ALPHA_PRO_BASE]*b.p[ALPHA_PRO_BASE]*m_s.m_b_rep_score; + + return s+down+over; + } + else + { + // undefined operation (replace base by basepair ??) + return DBL_NEG/4; + } + } + }; + + double del(RNA_Alphabet_Profile a,double down, double over) const + { + if(a.p[ALPHA_PRO_BASEPAIR]>0) + return a.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_del_score+down+over; + else + return a.p[ALPHA_PRO_BASE]*m_s.m_b_del_score+down+over; + }; + + double insert(double down,RNA_Alphabet_Profile b,double over) const + { + if(b.p[ALPHA_PRO_BASEPAIR]>0) + return b.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_del_score+down+over; + else + return b.p[ALPHA_PRO_BASE]*m_s.m_b_del_score+down+over; + }; + + double choice(double a, double b) const + { + return max(a,b); + }; + + double worst_score() const + { + return DBL_NEG; + }; + + DoubleSimiProfileAlgebra(const Score &s) + : m_s(s) {}; +}; + +/** Distance algebra for RNA profile forests */ +class DoubleDistProfileAlgebra : public DoubleScoreProfileAlgebraType +{ + private: + Score m_s; + + public: + double empty() const {return 0.0;}; + double replace(RNA_Alphabet_Profile a,double down, RNA_Alphabet_Profile b, double over) const + { + TRACE(DBG_ALGEBRA,"rep","inside!!!"); + + if(a.p[ALPHA_PRO_BASEPAIR]>0 && b.p[ALPHA_PRO_BASEPAIR]>0) + { + // pair replacement + return a.p[ALPHA_PRO_BASEPAIR]*b.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_rep_score + + down+over; + } + else + { + if(a.p[ALPHA_PRO_BASE]>0 && b.p[ALPHA_PRO_BASE]>0) + { + double s=0; + + // base replacement + for(int i=ALPHA_PRO_BASE_A;i<=ALPHA_PRO_BASE_U;i++) + for(int j=ALPHA_PRO_BASE_A;j<=ALPHA_PRO_BASE_U;j++) + s+= i==j ? a.p[i]*b.p[j]*m_s.m_b_match_score : a.p[i]*b.p[j]*m_s.m_b_rep_score; + + if(s==0) // no sequence information + s=a.p[ALPHA_PRO_BASE]*b.p[ALPHA_PRO_BASE]*m_s.m_b_rep_score; + + return s+down+over; + } + else + { + // undefined operation (replace base by basepair ??) + return DBL_POS/4; + } + } + }; + + double del(RNA_Alphabet_Profile a,double down, double over) const + { + if(a.p[ALPHA_PRO_BASEPAIR]>0) + return a.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_del_score+down+over; + else + return a.p[ALPHA_PRO_BASE]*m_s.m_b_del_score+down+over; + }; + + double insert(double down,RNA_Alphabet_Profile b,double over) const + { + if(b.p[ALPHA_PRO_BASEPAIR]>0) + return b.p[ALPHA_PRO_BASEPAIR]*m_s.m_bp_del_score+down+over; + else + return b.p[ALPHA_PRO_BASE]*m_s.m_b_del_score+down+over; + }; + + double choice(double a, double b) const + { + return min(a,b); + }; + + double worst_score() const + { + return DBL_POS; + }; + + DoubleDistProfileAlgebra(const Score &s) + : m_s(s) {}; +}; + +/* ****************************************** */ +/* SZAlgebra Classes */ +/* ****************************************** */ + +class IntSimiSZAlgebra : public IntScoreSZAlgebraType +{ + private: + Score m_s; + + public: + int empty() const {return 0;}; + int replace(RNA_Alphabet a,int down, RNA_Alphabet b) const + { + if(a==ALPHA_BASEPAIR && b == ALPHA_BASEPAIR) + return m_s.m_bp_rep_score+down; + else + { + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MIN/4; + else + { + if(a==b) + return m_s.m_b_match_score+down; + else + return m_s.m_b_rep_score+down; + } + } + }; + + int del(RNA_Alphabet a,int down) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down; + else + return m_s.m_b_del_score+down; + }; + + int insert(int down,RNA_Alphabet b) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down; + else + return m_s.m_b_del_score+down; + }; + + int choice(int a, int b) const + { + return max(a,b); + }; + + int worst_score() const + { + return INT_MIN; + }; + + IntSimiSZAlgebra(const Score &s) + : m_s(s) {}; +}; + + +class IntDistSZAlgebra : public IntScoreSZAlgebraType +{ + private: + Score m_s; + + public: + int empty() const {return 0;}; + int replace(RNA_Alphabet a,int down, RNA_Alphabet b) const + { + if(a==ALPHA_BASEPAIR && b == ALPHA_BASEPAIR) + return m_s.m_bp_rep_score+down; + else + { + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MAX/4; + else + { + if(a==b) + return m_s.m_b_match_score+down; + else + return m_s.m_b_rep_score+down; + } + } + }; + + int del(RNA_Alphabet a,int down) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down; + else + return m_s.m_b_del_score+down; + }; + + int insert(int down,RNA_Alphabet b) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down; + else + return m_s.m_b_del_score+down; + }; + + int choice(int a, int b) const + { + return min(a,b); + }; + + int worst_score() const + { + return INT_MAX; + }; + + IntDistSZAlgebra(const Score &s) + : m_s(s) {}; +}; + +/* ****************************************** */ +/* General Algebra Classe */ +/* ****************************************** */ + +/** Distance algebra for forests */ +class IntDist_Algebra : public IntScore_AlgebraType +{ + private: + Score m_s; + + public: + int empty() const {return 0;}; + + int replace(RNA_Alphabet a,int down, RNA_Alphabet b, int over) const + { + if(a==ALPHA_BASEPAIR && b == ALPHA_BASEPAIR) + return m_s.m_bp_rep_score+down+over; + else + { + if(a==ALPHA_BASEPAIR || b==ALPHA_BASEPAIR) + return INT_MAX/4; + else + { + if(a==b) + return m_s.m_b_match_score+down+over; + else + return m_s.m_b_rep_score+down+over; + } + } + }; + + int del(RNA_Alphabet a,int down,int over) const + { + if(a==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int insert(int down,RNA_Alphabet b,int over) const + { + if(b==ALPHA_BASEPAIR) + return m_s.m_bp_del_score+down+over; + else + return m_s.m_b_del_score+down+over; + }; + + int choice(int a, int b) const + { + return min(a,b); + }; + + int worst_score() const + { + return INT_MAX; + }; + + IntDist_Algebra(const Score &s) + : m_s(s) {}; +}; + + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_algebra.o new file mode 100755 index 0000000000000000000000000000000000000000..7e1d067b46d8b1de867d0d33f2dc0348a64d7951 GIT binary patch literal 129436 zcmeFa2YgjU+CM($o^x(4HzA!+Lb*Uf2_=Pk17au%9f8m_#E=9C1`<*z5}FVs#sF(u zUHhu<+IvA=+oEDy%i7n5Z573iilXxSerL`(_uM3~>#qNO-_QTU{p8M>d7ke)^UO2P zlrv|}&Boj*d77pP`=be6gi=EI)~eKC3Fsp-!~h#Aud^FIY@8j{IMo+(w`aQ+bN3i+ 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===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#include +#include + +#ifndef WIN32 +#include "config.h" +#endif + +#include "misc.h" +#include "rna_alignment.h" +#include "rnafuncs.h" +#include "utils.h" + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +void RNA_Alignment::makePairTable(map &pairs, bool first) const +{ + pair *baseIndex; // stores for each node in the alignment the index position of the left and right base (or -1) + RNA_Alphabet c; + + baseIndex=new pair[m_size]; + + // initialize pairs, all gaps + for(int i=size()-1;i>=0;i--) + { + baseIndex[i].first=-1; + baseIndex[i].second=-1; + } + + for(int i=size()-1;i>=0;i--) + { + // first or second component + if(first) + c=m_lb[i].a; + else + c=m_lb[i].b; + + if(isLeave(i)) + { + if(c!=ALPHA_GAP) + { + baseIndex[i].first=i; + baseIndex[i].second=i; + } + } + else + { + // internal node + // leftmost and rightmost base + bool lmBaseFound=false; + for(size_type r=0,h=i+1;r pairs; + makePairTable(pairs, first); + + // iterate through leaves nodes and use information of pairs + for(size_type i=0;i +*/ + +#ifndef _RNA_ALIGNMENT_H +#define _RNA_ALIGNMENT_H + +#include +#include +#include + +#include "alignment.h" +#include "ppforestali.h" +#include "rna_algebra.h" +#include "rnaforest.h" +#include "rnafuncs.h" +#include "types.h" + +#include "alignment.t.cpp" + +using namespace std; + +/** Alignment of RNAForests */ +class RNA_Alignment : public PPForestAli +{ +private: + string m_strname1; + string m_strname2; + + /** @name Implementations of virtual functions */ + //@{ + + void makeRepLabel(size_type node, RNA_Alphabet a, RNA_Alphabet b) + { + m_lb[node].a=a; + m_lb[node].b=b; + }; + + void makeDelLabel(size_type node, RNA_Alphabet a) + { + m_lb[node].a=a; + m_lb[node].b=ALPHA_GAP; + }; + + void makeInsLabel(size_type node, RNA_Alphabet b) + { + m_lb[node].a=ALPHA_GAP; + m_lb[node].b=b; + }; + + void showLabel(ostream &s,RNA_AlphaPair p) const + { + s << "[" << p.a << p.b << "]"; + }; + + //@} + + void makePairTable(map &pairs, bool first) const; + +public: + void setStructureNames(const string &s1,const string &s2); + const string& getStructureNameX() const {return m_strname1;}; + const string& getStructureNameY() const {return m_strname2;}; + void getSequenceAlignments(string &s1, string &s2) const; + void getStructureAlignment(string &s, bool first) const; + void generateXML(ostream &s) const; + void squigglePlot(const string &filename_suffix, const RNAFuncs::SquigglePlotOptions &options) const; +}; + +/* +class PW_RNA_Alignment: public Alignment +{ + public: + PW_RNA_Alignment(const RNAForest *ppfx, const RNAForest *ppfy, const IntScoreRNA_AlgebraType &alg) + : Alignment((const PPForest*)ppfx,(const PPForest*)ppfy,alg) {}; +};*/ + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alignment.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alignment.o new file mode 100755 index 0000000000000000000000000000000000000000..76e83d0ae0f6fb65f8691b678bd5044983771fc1 GIT binary patch literal 122216 zcmb@v2YeO98a6(&yXPb%Asq-!a>xlap(T_6LMQ>GCM2PXln{C+K_H=tln_F*q1djX zSFgQXML@*{)@xVnC|9otqF2#tLHR$=%W@n!FnRniqdFP$oIp-{E z@`ewRQVQokDNGS6332sOUCLI3Hll-Q?@-mXxa!No^{0}nCq-80#ncq0u756Al^m=Z z7_`1Vd+yx1s%F9Jym+^`{`usIlb)-2j8$u%W{Ub_$8`P~Ix?z@V~$usg4KDE)vMyG ziceMLeXrFF3`Xvwgqo`JPE}b!h1>k|IaR$ip}P3{_0L+>{jI9vk2f5OyYd<6_?uFc z_wSRJ*DMoNmj>@PBbUuU>9dY$n7oVy&;vOqLxj8uns;c`pi+gO~BDp#5cy&be 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case ALPHA_BASE_C: + return ALPHA_PRO_BASE_C; + case ALPHA_BASE_G: + return ALPHA_PRO_BASE_G; + case ALPHA_BASE_U: + return ALPHA_PRO_BASE_U; + case ALPHA_GAP: + return ALPHA_PRO_GAP; + case ALPHA_BASEPAIR: + return ALPHA_PRO_BASEPAIR; + case ALPHA_BASE: + return ALPHA_PRO_BASE; + default: + assert(true); + } + + return 0; // never reached !! +} + + + + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alphabet.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alphabet.h new file mode 100755 index 00000000..c48f8a66 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alphabet.h @@ -0,0 +1,99 @@ +#ifndef _RNA_ALPHABET_ +#define _RNA_ALPHABET_ + +#include + +using namespace std; + +/* +not every c++ compiler allows that enum types are used as +template arguments + +typedef enum + { + ALPHA_UNDEFINED=-1, + ALPHA_BASE_A=0, + ALPHA_BASE_C, + ALPHA_BASE_G, + ALPHA_BASE_U, + ALPHA_BASEPAIR, + ALPHA_GAP, + ALPHA_BASE, + RNA_ALPHABET_SIZE, + } RNA_Alphabet; +*/ + +typedef char RNA_Alphabet; + +/** pair alphabet of RNA_Alphabet */ +typedef struct {RNA_Alphabet a; RNA_Alphabet b;} RNA_AlphaPair; + + +//const int ALPHA_UNDEFINED=-1; +/* +const int ALPHA_BASE_A=0; +const int ALPHA_BASE_C=1; +const int ALPHA_BASE_G=2; +const int ALPHA_BASE_U=3; +const int ALPHA_BASEPAIR=4; +const int ALPHA_GAP=5; +const int ALPHA_BASE=6;*/ + + +const int ALPHA_BASE_A='a'; +const int ALPHA_BASE_C='c'; +const int ALPHA_BASE_G='g'; +const int ALPHA_BASE_U='u'; +const int ALPHA_BASEPAIR='P'; +const int ALPHA_GAP='-'; +const int ALPHA_BASE='B'; + +const int RNA_ALPHABET_SIZE=7; + +/*const int ALPHABET_SIZE = 256;*/ + +/* +class RNA_AlphabetTransformation +{ +private: + const static int m_alphabetsize; + const static int m_rna_alphabetsize; + + RNA_Alphabet m_alpha2RNA_Alpha[ALPHABET_SIZE]; + char m_RNA_Alpha2alpha[RNA_ALPHABET_SIZE]; + + void setMapEntry(RNA_Alphabet a, char c); +public: + RNA_AlphabetTransformation(); + + inline RNA_Alphabet RNA_AlphabetTransformation::alpha2RNA_Alpha(char c) + { + return m_alpha2RNA_Alpha[(unsigned int)c]; + }; + + inline char RNA_AlphabetTransformation::RNA_Alpha2alpha(RNA_Alphabet a) + { + return m_RNA_Alpha2alpha[(unsigned int)a]; + }; + +};*/ + +const int ALPHA_PRO_BASE_A=0; +const int ALPHA_PRO_BASE_C=1; +const int ALPHA_PRO_BASE_G=2; +const int ALPHA_PRO_BASE_U=3; +const int ALPHA_PRO_BASEPAIR=4; +const int ALPHA_PRO_GAP=5; +const int ALPHA_PRO_BASE=6; + +struct RNA_Alphabet_Profile +{ + RNA_Alphabet_Profile() {}; + + double p[RNA_ALPHABET_SIZE]; + string columnStr; +}; + +int alpha2RNA_Alpha(char c); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alphabet.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_alphabet.o new file mode 100755 index 0000000000000000000000000000000000000000..a926598f0fe2a168e0c2e3ba2781b3489e654533 GIT binary 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zw~0R@UQU$1IVtsa5uYUfmH08yt1xt9h-JiC#Qlj4#C61WVv2YM@f_mS#OsNV5#J*g zR+@fC6Kjcci4DYc#9rd@#0!W&Cf-B5pZF^AZQ{_0roUq14B~v^D&ksVH*qWR$HXg$ z_Yxl@{)6}iF*eEcH;Oo$cmVNeVhiys;`zkeh`Wf-5nm<_i<|aG5@!2D~pmN=JqBr!oek$4*Mr^IWBe;__Z{D`QkO+V$tNyH_@ z6~q+rIO4^`pAdHucC-DyAUx+UdgVRm> zgNaqdTH-Qd1MyhmiNyaV?j$}!e3JMf@pIz3TGL-EaSQPb;&$Sd#5;)}691PNtuyTu z689pO6Q>gEhzp5Jh({BfiCc*$62C{hfOsYGTH?LL2Z*l`-ys&wF#MGetBJFS%ZRIq zt;9~^*~IgR*Anj`zCe7F_%GsTf&u)WX|PxjdbN*Wfl~8$znIuSOb|B_`-rCy&nEtW x_%q@S#Jh +*/ + +#ifndef WIN32 +#include "config.h" +#endif + +#include + +#ifdef HAVE_LIBG2 +#include +#include +#endif + +#include +#include +#include +#include + +#include "matrix.h" +#include "rna_profile_alignment.h" +#include "rnafuncs.h" +#include "utils.h" + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library +#include "part_func.h" +#include "fold_vars.h" + +extern "C"{ +#include "fold.h" +} + +#endif + +#include "ppforest.t.cpp" + +ostream& operator <<(ostream &s,RNA_Alphabet_Profile p) +{ + + s.precision(2); + s << p.p[ALPHA_PRO_BASE_A] << "\\n"; + s.precision(2); + s << p.p[ALPHA_PRO_BASE_C] << "\\n"; + s.precision(2); + s << p.p[ALPHA_PRO_BASE_G] << "\\n"; + s.precision(2); + s << p.p[ALPHA_PRO_BASE_U] << "\\n"; + s.precision(2); + s << p.p[ALPHA_PRO_BASEPAIR] << "\\n"; + s.precision(2); + s << p.p[ALPHA_PRO_GAP]; + s.precision(2); + s << p.p[ALPHA_PRO_BASE]; + + // for(Uint i=0;i(RNAFuncs::treeSize(viennaStr)), + m_name(name), + m_numStructures(1) +{ + buildForest(baseStr,viennaStr); + addStrName(name); +}; + +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library +RNAProfileAlignment::RNAProfileAlignment(const string &baseStr, const string &name, const string &constraint, double t) + : PPForestAli(2*baseStr.length()), + m_name(name), + m_numStructures(1) +{ + char *viennaStr=NULL; + + // calculate partition function for the sequence + do_backtrack=1; + init_pf_fold(baseStr.length()); + + //if(constraint.length()>0) + //pf_fold((char*)baseStr.c_str(),(char*)constraint.c_str()); // expicit conversion to non-const value, but pf_fold does not alter baseStr + //else + pf_fold((char*)baseStr.c_str(),NULL); // expicit conversion to non-const value, but pf_fold does not alter baseStr + + viennaStr=new char[baseStr.length()+1]; + dangles=2; + fold((char*)baseStr.c_str(),viennaStr); + + setSize(RNAFuncs::treeSize(viennaStr)); + buildForest(baseStr,viennaStr,true); + + free_pf_arrays(); + delete[] viennaStr; + + // hasSequence=true; + addStrName(name); +} +#endif + +RNAProfileAlignment::RNAProfileAlignment(const string &filename) +{ + // read ppforest from file + size_type size; + ifstream s; + char *colStr; + + s.open(filename.c_str()); + + // first of all save the size + s.read((char*)&size,sizeof(size_type)); + s.read((char*)&m_numStructures,sizeof(Uint)); + + colStr=new char[m_numStructures+1]; + colStr[m_numStructures]=0; // terminate string + + // initialize structures + // ::PPForestBase(m_size); + // m_lb=new L[ppf.size()]; + initialize(size); + + // save the arrays + for(Uint i=0;i(&d),sizeof(double)); + l.p[r]=d; + } + + s.read(colStr,sizeof(char)*m_numStructures); + + l.columnStr=colStr; + m_lb[i]=l; + } + + s.read(reinterpret_cast(m_rb),sizeof(size_type)*size); + s.read(reinterpret_cast(m_noc),sizeof(size_type)*size); + // s.read((char*)m_sumUpCSF,sizeof(size_type)*size); + // s.read((char*)m_rmb,sizeof(size_type)*size); + + for(Uint r=0;r(ppf) +{ + m_numStructures=ppf.m_numStructuresX+ppf.m_numStructuresY; +}*/ + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +void RNAProfileAlignment::makeRepLabel(size_type node, RNA_Alphabet_Profile a, RNA_Alphabet_Profile b) + { + double p,q; + double m; + + p=m_numStructuresX; // weight number of structures in profile + q=m_numStructuresY; + m=p+q; + p/=m; + q/=m; + + // profile + for(int i=0;i 0) + // if(baseStr.length() != viennaStrLen) + // throw RNAForestExceptionInput(RNAForestExceptionInput::Error_BaseStringAndViennaStringIncompatible); + + nodeStack=new Uint[maxDepth+1]; + numChildrenStack=new Uint[maxDepth+1]; + baseposStack=new Uint[maxDepth+1]; + memset(nodeStack,0,sizeof(Uint)*maxDepth+1); + memset(numChildrenStack,0,sizeof(Uint)*maxDepth+1); + memset(baseposStack,0,sizeof(Uint)*maxDepth+1); + + // fill PPForest structure + stackPtr=0; + node=0; + for(Uint i=0;i &pairprob, double t,size_type i, size_type j) const +{ + size_type h; + double bestPairScore; + // list leftPairList; + //list rightPairList; + //Uint bestLeftIndex,bestRightIndex; + //Uint lastLeftIndex,lastRightIndex; + + // QWATCH(i); + // QWATCH(j); + + if(j==0) + return; + + if(isPair(i)) + { + // TRACE(DBG_GET_PROFILE_STRUCTURE,"Profile_RNA_Alignment_Forest::getStructureAlignmentFromCSF","basepair"); + // WATCH(DBG_GET_PROFILE_STRUCTURE,"Profile_RNA_Alignment_Forest::getStructureAlignmentFromCSF",m_lb[i].p[ALPHA_BASEPAIR]); + + bestPairScore=bestPairs(i); + + // backtrack best pairs + if(bestPairScore == bestPairs(i+1) + bestPairs(getRightmostBrotherIndex(i+1)) || m_lb[i].p[ALPHA_PRO_BASEPAIR] < t) + { + // i pairs not + // cout << "unpaired" << endl; + getStructureAlignmentFromCSF(s,pairprob,t,i+1,noc(i)); + // cout << "back to:" << endl; + // QWATCH(i); + // QWATCH(j); + } + else + { + // cout << "paired" << endl; + // i pairs + s += '('; + pairprob.push_back(m_lb[i].p[ALPHA_PRO_BASEPAIR]); + + // left path - righthand best pairs + h=i+1; + while(h < size() && isPair(h)) + { + // cout << "left" << endl; + // QWATCH(h); + + assert((int)noc(h)-1>=0); + getStructureAlignmentFromCSF(s,pairprob,t,rb(h+1),noc(h)-1); + h=h+1; + } + + + assert((int)noc(i)-2>=0); + getStructureAlignmentFromCSF(s,pairprob,t,rb(i+1),noc(i)-2); + // cout << "back to:" << endl; + // QWATCH(i); + // QWATCH(j); + + // right path - lefthand best pairs + h=getRightmostBrotherIndex(i+1); + while(h < size() && isPair(h)) + { + // cout << "right" << endl; + // QWATCH(h); + + assert((int)noc(h)-1>=0); + getStructureAlignmentFromCSF(s,pairprob,t,h+1,noc(h)-1); + //h=h+1; + h=getRightmostBrotherIndex(h+1); + } + + + s += ')'; + pairprob.push_back(m_lb[i].p[ALPHA_PRO_BASEPAIR]); + } + } + else + { + s+= '.'; + pairprob.push_back(m_lb[i].p[ALPHA_PRO_BASE]); + } + + // right forest + getStructureAlignmentFromCSF(s,pairprob,t,rb(i),j-1); +} + +double RNAProfileAlignment::bestPairs(size_type node) const +{ + size_type i=node; + double d1,d2; + + WATCH(DBG_GET_PROFILE_STRUCTURE,"RNAProfileForest::getStructureAlignment",node); + + if(isBase(node)) + return 0; + else + { + // node pairs not + d1=bestPairs(node+1) + bestPairs(getRightmostBrotherIndex(node+1)); + + // node pairs + d2=label(node).p[ALPHA_PRO_BASEPAIR]; + + // left path - righthand best pairs + i=node+1; + while(i < size() && isPair(i)) + { + d2+=bestPairs(getRightmostBrotherIndex(i+1)); + i=i+1; + } + + // right path - lefthand best pairs + i=getRightmostBrotherIndex(node+1); + while(isPair(i) && i < size()) + { + d2+=bestPairs(i+1); + i=getRightmostBrotherIndex(i+1); + } + + return max(d1,d2); + } +} + +#ifdef HAVE_LIBG2 // This features require the g2 library +void RNAProfileAlignment::drawBaseCircles(int device_id,const BaseProbs &bp,double center_x,double center_y) const +{ + const double box_size=6.0; + const double max_radius=3.0; + + double xpos,ypos; + int color; + // double dashes=0.5; + + // draw the base probabilities as circles on the edges of the square and the gap probability + // as the center square + + // upper left corner = a + xpos=center_x-box_size/2.0; + ypos=center_y+box_size/2.0; + + color=g2_ink(device_id,1,0,0); + g2_pen(device_id,color); + g2_filled_circle(device_id,xpos,ypos,max_radius*bp.a); + + // upper right corner = c + xpos=center_x+box_size/2.0; + ypos=center_y+box_size/2.0; + + color=g2_ink(device_id,0,1,0); + g2_pen(device_id,color); + g2_filled_circle(device_id,xpos,ypos,max_radius*bp.c); + + // lower right corner = g + xpos=center_x+box_size/2.0; + ypos=center_y-box_size/2.0; + + color=g2_ink(device_id,0,0,1); + g2_pen(device_id,color); + g2_filled_circle(device_id,xpos,ypos,max_radius*bp.g); + + // lower right corner = u + xpos=center_x-box_size/2.0; + ypos=center_y-box_size/2.0; + + color=g2_ink(device_id,1,0,1); + g2_pen(device_id,color); + g2_filled_circle(device_id,xpos,ypos,max_radius*bp.u); + + // gap in the center + color=g2_ink(device_id,0,0,0); + g2_pen(device_id,color); + g2_filled_circle(device_id,center_x,center_y,max_radius*bp.gap); + + // draw rectangle for orientation + //g2_set_dash(device_id,1,&dashes); + color=g2_ink(device_id,0.75,0.75,0.75); + g2_pen(device_id,color); + g2_rectangle(device_id,center_x-box_size/2,center_y-box_size/2,center_x+box_size/2,center_y+box_size/2); +} +#endif + +inline double RNAProfileAlignment::getMlBaseFreq(const BaseProbs &bp) const +{ + return max(max(max(bp.a,bp.c),bp.g),bp.u); +} + +char RNAProfileAlignment::getMlBase(const BaseProbs &bp) const +{ + double p = getMlBaseFreq(bp); + if(bp.a==p) + return ALPHA_BASE_A; + if(bp.c==p) + return ALPHA_BASE_C; + if(bp.g==p) + return ALPHA_BASE_G; + if(bp.u==p) + return ALPHA_BASE_U; + + assert(false); // you should never get so far ... + return 'x'; +} + +void RNAProfileAlignment::getSeqAli(string &seq,Uint row, Uint i, Uint j) const +{ + if(i==0 && j==getMaxLength(0)) + seq=""; + + if(j==0) + return; + + // basepair=internal node + if(isPair(i)) + { + getSeqAli(seq,row,i+1,noc(i)); + getSeqAli(seq,row,rb(i),j-1); + } + else + { + // base=leaf + seq+=m_lb[i].columnStr[row]; + getSeqAli(seq,row,rb(i),j-1); + } +} + +void RNAProfileAlignment::getStructAli(string &s,Uint row) const +{ + s=""; + + map pairs; + makePairTable(pairs, row); + + // iterate through leaves nodes and use information of pairs + for(Uint i=0;i &pairs, Uint row) const +{ + pair *baseIndex; // left and right base + RNA_Alphabet c; + + assert(row[m_size]; + + // initialize pairs, all gaps + for(int i=size()-1;i>=0;i--) + { + baseIndex[i].first=-1; + baseIndex[i].second=-1; + } + + for(int i=size()-1;i>=0;i--) + { + c=m_lb[i].columnStr[row]; + + if(isLeave(i)) + { + if(c!=ALPHA_GAP) + { + baseIndex[i].first=i; + baseIndex[i].second=i; + } + } + else + { + // internal node + // leftmost and rightmost base + bool lmBaseFound=false; + for(size_type r=0,h=i+1;r &pairprob, deque &baseprobs, double minFreq) const +{ + deque::iterator itPP; + // deque::iterator itBP; + string::iterator it; + + for(itPP=pairprob.begin(),it=structure.begin();itPP!=pairprob.end();itPP++,it++) + { + if(*itPPbase &baseprob) const +{ + BaseProbs bp; + + // generate base strings + for(size_type i=0;i &pairprob) const +{ + WATCH(DBG_GET_PROFILE_STRUCTURE,"Profile_RNA_Alignment_Forest::getStructureAlignment",size()); + + s=""; + getStructureAlignmentFromCSF(s,pairprob,t,0,getMaxLength(0)); +} + +#ifdef HAVE_LIBG2 // This features require the g2 library +void RNAProfileAlignment::squigglePlot(const string &filename, SquigglePlotOptions &options) const +{ + const double base_fontsize=8; + const Uint num_grey_colors=100; + const double min_grey_color=1.0; + + string seq,structure; + string base,structname; + float *X,*Y,min_X=0,max_X=0,min_Y=0,max_Y=0; + Uint i; + short *pair_table; + int id_PS,id; + int ps_grey_colors[num_grey_colors]; + int ps_color_red; + int ps_color_black; + double xpos,ypos; + + deque pairprob; + deque baseprobs; + + getStructureAlignment(options.minPairProb,structure,pairprob); + getSequenceAlignment(baseprobs); + + // filterConsensus(structure,pairprob,baseprobs,0.5); + + //assert(baseprobs.size() == structure.size()); + if(baseprobs.size() != structure.size()) + cerr << "Error in resolving consensus structure!" << endl; + + X = new float[structure.size()]; + Y = new float[structure.size()]; + + pair_table = make_pair_table(structure.c_str()); + i = naview_xy_coordinates(pair_table, X, Y); + if(i!=structure.size()) + cerr << "strange things happening in squigglePlot ..." << endl; + + // calculate image dimesions + for(i=0;ii+1) + { + // pairs in both structures + if(pairprob[i]==1) + g2_pen(id,ps_color_red); + else + g2_pen(id,ps_grey_colors[(int)floor(pairprob[i]*num_grey_colors-1)]); + + g2_line(id,X[i],Y[i],X[pair_table[i+1]-1],Y[pair_table[i+1]-1]); + } + } + + g2_flush(id); + g2_close(id); + + free(pair_table); + DELETE(X); + DELETE(Y); +} +#endif + +void RNAProfileAlignment::printSeqAli() const +{ + Uint i,l; + deque seqs; + string seq,info; + + // get alignment rows + for(i=0;i strs; + string str,info; + + // get alignment rows + for(i=0;i" << m_strNames[i] << endl; + cout << seq << endl; + if(!noStructure) + cout << str << endl; + } +} + +void RNAProfileAlignment::printConsensus(double minPairProb) const +{ + const int mountain_high=10; + int j; + + string seq,structure; + + deque baseprobs; + deque pairprob; + + getSequenceAlignment(baseprobs); + getStructureAlignment(minPairProb,structure,pairprob); + + // build sequence + deque::const_iterator it; + for(it=baseprobs.begin();it!=baseprobs.end();it++) + { + seq += getMlBase(*it); + } + +// assert(seq.size() == structure.size()); + if(seq.size() != structure.size()) + cerr << "Error in resolving consensus structure!" << endl; + + for(Uint i=0;i=1-(1/(double)mountain_high)*(double)j) + cout << "*"; + else + cout << " "; + } + } + cout << endl; + } + + cout << setw(25) << " " << seq.substr(i,55) << endl; + cout << setw(25) << " " << structure.substr(i,55) << endl; + + // show structure frequency mountain + for(j=0;j=(1/(double)mountain_high)*(double)j) + cout << "*"; + else + cout << " "; + } + } + cout << endl; + } + + cout << endl; + } +} + +void RNAProfileAlignment::addStrNames(const deque& strNames) +{ + deque::const_iterator it; + for(it=strNames.begin();it!=strNames.end();it++) + m_strNames.push_back(*it); +} + +void RNAProfileAlignment::save(const string &filename) +{ + ofstream s(filename.c_str()); + + // save the pforest to stream in binary format + + // first of all save the size + s.write(reinterpret_cast(&m_size),sizeof(size_type)); + s.write(reinterpret_cast(&m_numStructures),sizeof(Uint)); + + // save the arrays + for(Uint i=0;i(&m_lb[i].p[r]),sizeof(double)); + + s.write(reinterpret_cast(m_lb[i].columnStr.c_str()),sizeof(char)*m_numStructures); + } + + + // for(Uint i=0;i(&m_lb[i]),sizeof(label_type)*m_size); + // } + + // s.write(reinterpret_cast(m_lb),sizeof(label_type)*m_size); + s.write(reinterpret_cast(m_rb),sizeof(size_type)*m_size); + s.write(reinterpret_cast(m_noc),sizeof(size_type)*m_size); + + for(Uint r=0;r(ss.str().c_str()),sizeof(char)*20); + } + + + // s.write(reinterpret_cast(m_sumUpCSF),sizeof(size_type)*m_size); + // s.write(reinterpret_cast(m_rmb),sizeof(size_type)*m_size); + + // s.write(m_name; + //Uint m_numStructures; + //Uint m_numStructuresX; + //Uint m_numStructuresY; + //deque m_strNames; + //bool hasSequence; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_profile_alignment.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_profile_alignment.h new file mode 100755 index 00000000..57b2e18d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_profile_alignment.h @@ -0,0 +1,141 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _RNA_PROFILE_ALIGNMENT_H +#define _RNA_PROFILE_ALIGNMENT_H + +#include +#include +#include + +#include "alignment.h" +#include "matrix.h" +#include "ppforestali.h" +#include "rna_algebra.h" +#include "types.h" + +//#include "alignment.t.cpp" + +using namespace std; + +class RNAProfileAlignment + : public PPForestAli +{ + public: + // typedef typename PPForestAli::size_type size_type; + + struct SquigglePlotOptions + { + bool hideBaseNumbers; + Uint baseNumInterval; + bool greyColors; + bool mostLikelySequence; + double minPairProb; + }; + + struct BaseProbs + { + double a; + double c; + double g; + double u; + double gap; + double base; + }; + + private: + string m_name; + Uint m_numStructures; + Uint m_numStructuresX; + Uint m_numStructuresY; + deque m_strNames; + bool hasSequence; + + void makeRepLabel(size_type node, RNA_Alphabet_Profile a, RNA_Alphabet_Profile b); + void makeDelLabel(size_type node, RNA_Alphabet_Profile a); + void makeInsLabel(size_type node, RNA_Alphabet_Profile b); + + void showLabel(ostream &s,RNA_Alphabet_Profile p) const; + void makeLabel(RNA_Alphabet_Profile &a,char c); + + /** Build forest from structure, sequence pair. */ + void buildForest(const string &baseStr, const string &viennaStr, bool use_bp_prob=false); + + void getStructureAlignmentFromCSF(string &s, deque &pairprop, double t,size_type i, size_type j) const; + double bestPairs(size_type node) const; + void drawBaseCircles(int device_id,const BaseProbs &bp,double center_x,double center_y) const; + double getMlBaseFreq(const BaseProbs &baseprobs) const; + char getMlBase(const BaseProbs &bp) const; + void getSeqAli(string &seq,Uint row,Uint i,Uint j) const; + void getStructAli(string &str,Uint row) const; + void makePairTable(map &pairs, Uint row) const; + void filterConsensus(string &structure, deque &pairprob, deque &baseprobs, double minFreq) const; + void addStrName(const string &strName) {m_strNames.push_back(strName);}; + + inline bool isBase(size_type node) const + { + if(label(node).p[ALPHA_PRO_BASE] > 0) + return true; + else + return false; + }; + + inline bool isPair(size_type node) const {return !isBase(node);}; + +public: + RNAProfileAlignment(const string &baseStr, const string &viennaStr, const string &name); + RNAProfileAlignment(const string &baseStr, const string &constraint, const string &name, double t); + RNAProfileAlignment(const string &filename); + + void printSeqAli() const; + void printStrAli() const; + void printConsensus(double minPairProb) const; + void printFastaAli(bool noStructure=false) const; + + void squigglePlot(const string &filename, SquigglePlotOptions &options) const; + void getSequenceAlignment(deque &baseprob) const; + void getStructureAlignment(double t, string &s, deque &pairprob) const; + string getName() const {return m_name;}; + void setName(const string &name) {m_name=name;}; + Uint getNumStructures() const {return m_numStructures;}; + const deque& getStrNames() const {return m_strNames;}; + void addStrNames(const deque& strNames); + void save(const string &filename); + + RNAProfileAlignment(Uint numStructuresX,Uint numStructuresY) : + PPForestAli(), + m_numStructures(numStructuresX + numStructuresY), + m_numStructuresX(numStructuresX), + m_numStructuresY(numStructuresY){}; +}; + +/* +class Profile_RNA_Alignment: public Alignment +{ + private: + string m_name; + + public: + Profile_RNA_Alignment(const RNAProfileForest *ppfx, const RNAProfileForest *ppfy, const DoubleScoreProfileAlgebraType &alg) + : Alignment((const PPForest*)ppfx,(const PPForest*)ppfy,alg) + { + m_name=ppfx->getName(); + m_name+="."; + m_name+=ppfy->getName(); + }; + + string getName() const {return m_name;}; +}; +*/ + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_profile_alignment.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rna_profile_alignment.o new file mode 100755 index 0000000000000000000000000000000000000000..35c332b815992bfacb362c003a9eebde6531b911 GIT binary patch literal 362272 zcmeEv4SW^F)%R|)A(td@qX`-z)F?qg`BcyZP($DXqESGisKlaGtMv;dLHvk(Bp0(T z3#oFITBBHLOBH?aBQ_v`AT$X|Eh^STxro(PuA$ZnA|jRd|39<4_ui0DpSI8QzVGj+ 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distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef WIN32 +#include "config.h" +#endif + +#ifndef HAVE_LIBRNA +#undef HAVE_LIBG2 +#endif + +#include "rnaforest.h" +#include "rnafuncs.h" + +#include "ppforest.t.cpp" + +/* ****************************************** */ +/* Constructor and Destruktor functions */ +/* ****************************************** */ + +RNAForest::RNAForest(const string &baseStr, const string &viennaStr, const string &name) +: PPForest(RNAFuncs::treeSize(viennaStr)), + m_baseStr(baseStr), + m_viennaStr(viennaStr) +{ + if(name.empty()) + m_name="unknown"; + else + m_name=name; + + buildForest(baseStr,viennaStr); +}; + +/* ****************************************** */ +/* Private functions */ +/* ****************************************** */ + +inline void RNAForest::makeLabel(RNA_Alphabet &a,char c) +{ + a=c; +} + +inline void RNAForest::showLabel(ostream &s,RNA_Alphabet a) const +{ + s << a; +} + +void RNAForest::buildForest(const string &baseStr, const string &viennaStr) +{ + Ulong basePairCount=0,maxDepth=0,stackPtr; + Uint baseStrLen,viennaStrLen,node,*nodeStack, *numChildrenStack; + + assert(RNAFuncs::isRNAString(baseStr)); + + RNAFuncs::isViennaString(viennaStr,basePairCount,maxDepth); + + baseStrLen=baseStr.length(); + viennaStrLen=viennaStr.length(); + + // check if base string and vienna string have the same length + // if(baseStr.length() > 0) + // if(baseStr.length() != viennaStrLen) + // throw RNAForestExceptionInput(RNAForestExceptionInput::Error_BaseStringAndViennaStringIncompatible); + + nodeStack=new Uint[maxDepth+1]; + numChildrenStack=new Uint[maxDepth+1]; + memset(nodeStack,0,sizeof(Uint)*maxDepth+1); + memset(numChildrenStack,0,sizeof(Uint)*maxDepth+1); + + // fill PPForest structure + stackPtr=0; + node=0; + for(Uint i=0;i > ®ions, const RNAFuncs::SquigglePlotOptions &sqOptions) const +{ + RNAFuncs::drawRNAStructure(m_baseStr,m_viennaStr,filename_prefix,m_name,regions,sqOptions); +} +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnaforest.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnaforest.h new file mode 100755 index 00000000..1fdb5e79 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnaforest.h @@ -0,0 +1,61 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2004 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _RNA_FOREST_H_ +#define _RNA_FOREST_H_ + +#include + +#include "algebra.h" +#include "ppforest.h" +#include "rna_alphabet.h" +#include "rnafuncs.h" + + +using namespace std; + + +/** RNAForest encapsulates the forest representation of an RNA */ +class RNAForest + : public PPForest +{ +private: + typedef PPForest PPForestRNAType; + + string m_name; + string m_baseStr; + string m_viennaStr; + + void showLabel(ostream &s,RNA_Alphabet a) const; // virtual function of PPForest + void makeLabel(RNA_Alphabet &a,char c); + + /** Build forest from structure, sequence pair. */ + void buildForest(const string &baseStr, const string &viennaStr); + +public: + /** Build forest from structure sequence pair. + * This allows for direct use of Vienna RNA strings. + * e.g.: str="(..(...))", seq="accguuucu" + */ + RNAForest(const string &baseStr, const string &viennaStr, const string &name); + + const string& getName() const {return m_name;}; + const string& getBaseStr() const {return m_baseStr;}; + const string& getViennaStr() const {return m_viennaStr;}; + + void plot2d(const string &filename_prefix, const list > ®ions, const RNAFuncs::SquigglePlotOptions &sqOptions) const; +}; + +#endif + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnaforest.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnaforest.o new file mode 100755 index 0000000000000000000000000000000000000000..832eba7add68dfe0591f2af0541a7324a2cfac95 GIT binary patch literal 88932 zcmeFa33yf2)jzz?aKnWgAR&<T=? z;huB$T5IpU_S$Q&z4qGs9QH?6E;S58IDdw)L_8(L@_s5+C<&&Bg`&hEmG{c7mk+!( zygQQFT^a0JGBL9|l7?H_p|Wh;QoAFmxCIZDO*!zuL_FDDnG;|8?AWnmk3M+#&>buQ z`8RH;IPg|UcV+64$Xf(;M}pm}(z+`D-W7SRYt_*sk#`Aoa-MVl;B!`5psG50DDti> 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+#include "rnaforester_options.h" + +RNAforesterOptions::RNAforesterOptions(int argc, const char **argv) +: m_argv(argv) +{ + m_options=new OptionsInfo[NumberOfOptions]; + + setOption(Help, "--help",""," ","shows this help info",false); + setOption(Version, "--version",""," ","shows version information",false); + setOption(OutputAlignmentDotFormat, "-dot","=file"," ","show alignment forest in dot format",true); + setOption(CalculateDistance, "-d",""," ","calculate distance instead of similarity",false); + setOption(RelativeScore, "-r",""," ","calculate relative score",false); + setOption(LocalSimilarity, "-l",""," ","local similarity",false); + setOption(LocalSubopts, "-so","=int"," ","local suboptimal alignments within int%",false); + setOption(SmallInLarge, "-s",""," ","small-in-large similarity",false); + setOption(Multiple, "-m",""," ","multiple alignment mode",false); + setOption(ClusterThreshold, "-mt","=double"," ","clustering threshold",false); + setOption(ClusterJoinCutoff, "-mc","=double"," ","clustering cutoff",false); +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + setOption(PredictProfile, "-p",""," ","predict structures from sequences",false); + setOption(PredictMinPairProb, "-pmin","=double"," ","minimum basepair frequency for prediction",false); +#endif + setOption(SaveProfile, "-sp","=file"," ","save profile",false); + setOption(ProfileSearch, "-ps","=file"," ","profile search",false); + + setOption(TreeEdit, "-e",""," ","use tree edit model to calculate distance and similarity",true); + setOption(GlobalAlignment, "-g",""," ","calculate global alignment in its original version",true); + setOption(BpRepScore, "-pm","=int"," ","basepair(bond) match score",false); + setOption(BpDelScore, "-pd","=int"," ","basepair bond indel score",false); + setOption(BMatchScore, "-bm","=int"," ","base match score",false); + setOption(BRepScore, "-br","=int"," ","base mismatch score",false); + setOption(BDelScore, "-bd","=int"," ","base indel score",false); + setOption(RIBOSUMScore, "--RIBOSUM",""," ","RIBOSUM85-60 scoring matrix (base-pair substitutions)",false); + setOption(ConsensusMinPairProb, "-cmin","=double"," ","minimum basepair frequency for consensus structure",false); +#ifdef HAVE_LIBG2 // This features require the g2 library + setOption(MakeSquigglePlot, "-2d",""," ","generate alignment 2D plots in postscript format",false); + setOption(SquiggleHideBaseNumbers, "--2d_hidebasenum",""," ","hide base numbers in 2D plot",false); + setOption(SquiggleBaseNumberInterval,"--2d_basenuminterval","=n"," ","show every n-th base number",false); + setOption(SquiggleGreyColors, "--2d_grey",""," ","use only grey colors in 2D plots",false); + setOption(SquiggleScaleFactor, "--2d_scale","=double"," ","scale factor for the 2d plots",false); + setOption(SquiggleGenerateFIG, "--2d_fig",""," ","generate additional fig file of 2d plot",false); +#ifdef HAVE_LIBGD // This features require the gd library + setOption(SquiggleGeneratePNG, "--2d_png",""," ","generate additional png file of 2d plot",false); + setOption(SquiggleGenerateJPG, "--2d_jpg",""," ","generate additional jpg file of 2d plot",false); +#endif +#endif + setOption(ReadFromFile, "-f","=file"," ","read input from file",false); + // setOption(SaveMultipleAliFile, "-sm","=file"," ","save multiple alignment as binary file",true); + setOption(NoScale, "--noscale",""," ","suppress output of scale",false); + setOption(MakeDotForInputTrees, "-idot",""," ","make dot files for the input trees",true); +#ifdef HAVE_LIBRNA // This features require the ViennaRNA library + setOption(GenerateXML, "--xml",""," ","generate xml output for Jforester",true); +#endif + setOption(SecretHelp, "--shelp",""," ","shows this help info",true); + setOption(ShowOnlyScore, "--score",""," ","compute only scores, no alignment",false); + setOption(FastaOutput, "--fasta",""," ","generate fasta output of alignments",false); + + setOption(SpaceTimeInfo, "--spacetime",""," ","space and time measurements",true); + + // set the arguments that can be seperated by spaces + stringstream ss; + for(int i=0;ihas(m_options[option].tag); +} + +void RNAforesterOptions::help() +{ + cout << "Usage: " << m_argv[0] << " [options]" << endl; + + for(int i=0;igOYhTMXX&=(c2> zOr^J8D!mn?7uvyUr8iyY!Y8x?Yg*~_rYOB(I%oM)k;l*bUHxtO3+Y9dN6|bThfhfF zJ35h0Z(b@ryC#(1L;Bm&8?1l!IZElB@BeiF9nRlRigsNs$M5R8(fn<&@9f{pFywEH zGCWD=!YAbKMV(0JuS@x}@9cRu(Z7(tc}mpM4e50$J!@;>6VkgYcin1TcS^WO4A=cg z*QM`!Lh8Po>AG;=DJqckeWzRzMbDN=Z?djSr*~GWoIjUJ@A_PN!>?4i*bVrE{9T<( z?;54Iy{@rxF7`s3+QB=z&SYKqSpMwVQ@Jjj-{hJodN3rSlXjhbzNYKa`HQ|gD0)HX?RmG>zwo@@ zCcTiq=dO*S3(BN-elEQilwKFCIDmb99M4?{@kZ(t9+Q-Y%=7Xi-Q+*M&bH%B6RW(i@{f zvh;RHrS}}^S>4;`TQ^71>{Lg$^z7fOx^6AIfX~a*!=3zzaP(d-e|Fu*;YVV)ZX^Az zOXJUbmR^~1w(CRP+Qpa7RlVst%kN12v!4vrKWi)L^oAZXDEj-SbdpcFZ#WK2pI;;T z%fG^T?Cox+y_B@|SeyqQSIEkB_8WMdrIdI>bWK2Fo zB9m;%XNZ$b>0^^D$!CZp#0@%}qJIbJUuk}ZM=$F9T`I0>LUp0tj<4m|#?BF{pY>9m!|wkXj%_R)q55j!_!M`%S@cxy`d{Ua 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z_+$7Kd=|b7KY*LH`}=)}t}lkhG04qUIpr@Ir}12(`m*bPsG-+))Z z>)>7Re)uAM6@CbZbn-lKB-{hm!=qp`JQm&#AA*ml z3h#rD!PkuIN70*bgQNZR!{8|62HNKY?rj_#MYCXoQR%nCW8g`~4WsBA#^GA0$N6iG z`u&aY$MFB)WAG{X5_}DQ1P6EfbcVuB;Er%KoD8SH*>EmwflJ^C@N4iK_)T~{yb0b5 zAB4}qXW?t`P53_i2yWWrpW}0IJ2(nXg1f=la4u|tOW;a)9K6%0`gsbz20w&r_4@C( zffL~zS3r$VhqcIhuPs=U4oFEMVSb;0mj&c9+*yMB-3wU+zq z)`goI_5C&+ZwKq(Bsd=)36F+L;c4*e@D`);_fz-^{3jf>!hb&KMPG%dasFDP z^7jzOZ}9z};NX@1cWc7W!7bsgaCdkBJP5YKqv1E;Iq)WUE4&{*1b+`-h3g%|bHPK6 zpVj(r*v$DZcn;^k39mHjd9UO9pK$(e_yl|!z75}l8-Cf}?=x^4xE-8jRK2V)ZWcwy z!V@`vu2J{DfaBZv{(s4A zw}dm{e(*@R03K@`9!1x3d?WlJ{9pJ8d;R#U$}*FC%;Fc#X1kS<1v2k)4?@SB(*gfyh{|F zV;rmfLpat?-0>+K-(;+fqCdh72l?Ye?Rd1``*iTQD7x2bVc(c%D(u-OI7m7*|f`aeRSM<+qyS?;AIXqQ^P@xl!f)7RT=x zRS%meA9nv?M%B+ajwc#*zj+)V&hfDvpTP0O9AC=u_c^|UV^w8ju{9%&dcM7lO1I6Z zFV8Y6pLZCQzvqm~*BbVF +#include +#include +#include +#include + +#include "debug.h" +#include "misc.h" +#include "rnafuncs.h" +#include "utils.h" + +#ifndef WIN32 +#include "config.h" +#endif + +#ifndef HAVE_LIBRNA +#undef HAVE_LIBG2 +#endif + +#include + +#ifdef HAVE_LIBG2 +#include +#include +#include + +#ifdef HAVE_LIBGD +#include +#endif +#endif + +#define COLOR_RED 0 +#define COLOR_GREEN 1 +#define COLOR_BLUE 2 +#define COLOR_YELLOW 3 +#define COLOR_MAGENTA 4 +#define COLOR_TURKIS 5 +#define NUM_COLORS 6 + +#define COLOR_DEF_RED 1,0,0 +#define COLOR_DEF_GREEN 0,1,0 +#define COLOR_DEF_BLUE 0,0,1 +#define COLOR_DEF_YELLOW 1,1,0 +#define COLOR_DEF_MAGENTA 0,1,1 +#define COLOR_DEF_TURKIS 1,0,1 + +bool RNAFuncs::isRNAString(const string &str) +{ + string::const_iterator it; + for(it=str.begin(); it!=str.end(); it++) + { + switch(tolower(*it)) + { + case 'a': + case 'c': + case 'g': + case 'u': + case 't': + case '.': + case '-': + break; + default: + return false; + } + } + + return true; +} + + +bool RNAFuncs::isViennaString(const string &str, Ulong &basePairCount, Ulong &maxDepth) +{ + long brackets=0; + maxDepth=0; + basePairCount=0; + + string::const_iterator it; + for(it=str.begin(); it!=str.end(); it++) + { + switch(*it) + { + case '.': + break; + case '(': + brackets++; + basePairCount++; + if(brackets>0) + maxDepth=max(static_cast(maxDepth),static_cast(brackets)); + break; + case ')': + if(brackets) + { + brackets--; + break; + } + default: + return false; + } + } + + // equal nr of opening and closing brackets ? + if(brackets) + return false; + + return true; +} + +#ifdef HAVE_LIBG2 // This features require the g2 library +void RNAFuncs::drawRNAStructure(const string &seq, const string &structure, const string &filename_prefix, const string &structname, const list > ®ions, const SquigglePlotOptions &options) +{ + const double base_fontsize=12; + + float *X, *Y,min_X=0,max_X=0,min_Y=0,max_Y=0; + Uint i; + short *pair_table; + int id_PS,id_FIG=0,id; + int color_black, *colors; + double xpos,ypos; + char buf[10]; + string filename; + double *points; + int numPoints; + +#ifdef HAVE_LIBGD + int id_PNG=0,id_JPG=0; +#endif + + X = new float[structure.size()]; + Y = new float[structure.size()]; + points=new double[2*structure.size()]; + colors=new int[NUM_COLORS]; + + assert(seq.size() == structure.size()); + + pair_table = make_pair_table(structure.c_str()); + i = naview_xy_coordinates(pair_table, X, Y); + if(i!=structure.size()) + cerr << "strange things happening in squigglePlot ..." << endl; + + // scale image + for(i=0;i(options.scale); + Y[i]*=static_cast(options.scale); + } + + // calculate image dimensions + for(i=0;ii+1) + { + // pairs in both structures + g2_line(id,X[i],Y[i],X[pair_table[i+1]-1],Y[pair_table[i+1]-1]); + } + } + + // draw regions + g2_set_line_width(id,0.4); + list >::const_iterator it; + Uint regionNr=0; + + for(it=regions.begin();it!=regions.end();it++) + { + double center_x=0,center_y=0; + + // fill coordinate list + for(i=0;i < it->second;i++) + { + points[2*i]=X[it->first+i]; + points[2*i+1]=Y[it->first+i]; + + center_x+=X[it->first+i]; + center_y+=Y[it->first+i]; + } + numPoints=it->second-1; + center_x/=numPoints; // center of gravity + center_y/=numPoints; + + g2_pen(id,colors[regionNr % NUM_COLORS]); + g2_poly_line(id,numPoints,points); + sprintf(buf,"%d",regionNr+1); + g2_string(id,center_x,center_y,buf); // draw region number + + regionNr++; + } + + // mark 5' end + + g2_pen(id,color_black); + g2_string(id,X[0]-20,Y[0],"5'"); + + g2_set_font_size(id,base_fontsize*options.scale); + g2_set_line_width(id,0.2); + + // draw sequence + for(i=0;i(options.scale); + Y[i]*=static_cast(options.scale); + } + + // calculate image dimensions + for(i=0;ii+1 && (unsigned short)alt_pair_table[i+1]>i+1) + { + // pairs in both structures + g2_pen(id,ps_color_black); + g2_line(id,X[i],Y[i],X[pair_table[i+1]-1],Y[pair_table[i+1]-1]); + } + else + { + if((unsigned short)pair_table[i+1]>i+1 && (unsigned short)alt_pair_table[i+1]<=i+1) + { + // pairs only in first structure + if(atX) + g2_pen(id,ps_color_blue); + else + g2_pen(id,ps_color_green); + + g2_line(id,X[i],Y[i],X[pair_table[i+1]-1],Y[pair_table[i+1]-1]); + } + else + { + if((unsigned short)pair_table[i+1]<=i+1 && (unsigned short)alt_pair_table[i+1]>i+1) + { + // pairs only in second structure + if(atX) + g2_pen(id,ps_color_green); + else + g2_pen(id,ps_color_blue); + + double dashes=2.0; + g2_set_dash(id,1,&dashes); + g2_line(id,X[i],Y[i],X[alt_pair_table[i+1]-1],Y[alt_pair_table[i+1]-1]); + dashes=0; + g2_set_dash(id,1,&dashes); + } + } + } + } + + + // draw structure names + // x-at-y or y-at-x + if(atX) + { + g2_pen(id,ps_color_green); + g2_string(id,min_X,max_Y-10,(char*)strname2.c_str()); + g2_pen(id,ps_color_black); + g2_string(id,min_X,max_Y-20,"at"); + g2_pen(id,ps_color_blue); + g2_string(id,min_X,max_Y-30,(char*)strname1.c_str()); + } + else + { + g2_pen(id,ps_color_blue); + g2_string(id,min_X,max_Y-10,(char*)strname1.c_str()); + g2_pen(id,ps_color_black); + g2_string(id,min_X,max_Y-20,"at"); + g2_pen(id,ps_color_green); + g2_string(id,min_X,max_Y-30,(char*)strname2.c_str()); + } + + g2_flush(id); + g2_close(id); + + free(pair_table); + free(alt_pair_table); + DELETE(X); + DELETE(Y); +} +#endif + +#ifdef HAVE_LIBRNA +void RNAFuncs::generateRNAAlignmentXML(const string &structure, const string &altStructure, const string &seq1, const string &seq2, const string &strname1, const string &strname2, ostream &s) +{ + string base; + Uint i; + float *X, *Y; + short *pair_table,*alt_pair_table; + Uint basenr_x=1, basenr_y=1; + string filename; + + X = new float[structure.size()]; + Y = new float[structure.size()]; + + assert(seq1.size() == seq2.size()); + assert(seq1.size() == structure.size()); + assert(seq1.size() == altStructure.size()); + + // calculate coordinates + pair_table = make_pair_table(structure.c_str()); + alt_pair_table = make_pair_table(altStructure.c_str()); + i = naview_xy_coordinates(pair_table, X, Y); + if(i!=structure.size()) + cerr << "strange things happening in squigglePlot ..." << endl; + + // generate XML + s << "" << endl; + + // seqalignment + s << " " << endl; + for(i=0;i" << endl; + if(seq1[i]!='-') + basenr_x++; + + if(seq2[i]!='-') + basenr_y++; + } + s << " " << endl; + + // pairs + s << " " << endl; + for(i=0;ii+1 && (unsigned short)alt_pair_table[i+1]>i+1) + { + s << " " << endl; + } + else + { + if((unsigned short)pair_table[i+1]>i+1) + { + s << " " << endl; + } + else + { + if((unsigned short)alt_pair_table[i+1]>i+1) + s << " " << endl; + } + } + } + s << " " << endl; + + // coordinates + // x structure + s << " " << endl; + s << " " << endl; + for(i=0;i" << endl; + } + s << " " << endl; + s << " " << endl; + + DELETE(X); + DELETE(Y); + X = new float[altStructure.size()]; + Y = new float[altStructure.size()]; + + // y structure + i = naview_xy_coordinates(alt_pair_table, X, Y); + if(i!=structure.size()) + cerr << "strange things happening in squigglePlot ..." << endl; + + s << " " << endl; + s << " " << endl; + for(i=0;i" << endl; + } + s << " " << endl; + s << " " << endl; + s << "" << endl; + + free(pair_table); + free(alt_pair_table); + DELETE(X); + DELETE(Y); +} +#endif + +void RNAFuncs::printAli(const string &name1, const string &name2, const string &seq1, const string &seq2, const string &str1, const string &str2) +{ + Uint i; + string info; + + for(i=0;i +#include + +#include "types.h" + +using namespace std; + +class RNAFuncs +{ + public: + struct SquigglePlotOptions + { + bool hideBaseNumbers; + Uint baseNumInterval; + bool greyColors; + bool generatePNG; + bool generateJPG; + bool generateFIG; + double scale; + }; + + static bool isRNAString(const string &str); + static bool isViennaString(const string &str, Ulong &basePairCount, Ulong &maxDepth); + static void drawRNAStructure(const string &seq, const string &structure, const string &filename_prefix, const string &structname, const list > ®ions, const SquigglePlotOptions &options); + static void drawRNAAlignment(const string &structure, const string &altStructure, const string &seq1, const string &seq2, const string &strname1, const string &strname2, const string &filename_prefix, const bool atX, const SquigglePlotOptions &options); + static void generateRNAAlignmentXML(const string &structure, const string &altStructure, const string &seq1, const string &seq2, const string &strname1, const string &strname2, ostream &s); + static void printAli(const string &name1, const string &name2, const string &seq1, const string &seq2, const string &str1, const string &str2); + static Uint treeSize(const string &viennaStr); + +}; + +#endif + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnafuncs.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/rnafuncs.o new file mode 100755 index 0000000000000000000000000000000000000000..dacb82ef8bfb2f4fd479cd1c179b398d047995f7 GIT binary patch literal 134520 zcmdqKd3;nw_BLL3=_Z7bPG^D81WZCC39?8)AQB)fVG*Ki2?&NoKtPZ+K~UL*sIiTL 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zI3vn)3rn&LtFSts;j`?(PVCQDIEmAk&UO5RpYj`K@&Yfjz|1IbAwJA1tk0*|o-eWw z2kPvgB$n}cQBJ#{E5FXUuu-MAWN_$A7uiYu_b%6A181MS8+Ap=N5j&Z}P?}+^WJ9e=I1=i3;ctBvCzDze-W191FX$@e2(qdhXXjClevO#aToXU z2cBl``B9#Hyo)7Rh1K~a8?h~4U|$YoN@%ctsp`2*=Q@7EPkDsLn9Zv!vLMP`jOF<- zpWr{)lr7kmJvo-+xr(c~mD`!gES}><{>9u2qnx+#PL^YNKE@~5j4j!PJvfSExsXfw z0k<)eSv<#!{EN94MR|)ej{jgq)?jV6WE*y6Prl00oX%NH=Q@7EPkER}d5OQWz~U%( zA>Pe$> zCbUGbe=861cUFBPI$oQtIGp2{%8lH@y}ZnVE28Ta<0GsZnmZ=uG1k$Z$Ru`lygU19 zAEX|}(b}hR5#QiizQd2Wi{FOkjfwdwPn2s*vA~;Sa^Aw6;ah0&(BNHMXmI>tbrr{( zs#~agsr#yfA4hZgPgiHCH>mfi52!DwFRKgXiuxA`4f2#%KdjDq&DtPeL-nm;zqY}C z>H1d)4H}!MTdD`DN2uqim#ep{^MwZQZdgQn&bs`+^$M0UCtm>;;*Ilz<^8|)4Caxu zo`Lb&Z{#hfF3;+$!P>0HhP*Mq=hW@kft}cmz1WvG)?<`tlJ`W8Z)?o zo4B33xR?8Qm`8bnr+As!yvl2gaUbODiyN$O0d>xO6x28Fqhi{NGmhn$bDst0-?-1J zXs^y1tj(PJFgU-dx&_16vkvducI?Jp?8|{1#jzaE$(+tvoX166#+6KC1~+gMH*+iZ zavu-yAP@5>Pw*5kGn-d=jRk_W2-l+!i?A4rGiP7n;Ny68X_jMo=Il2dd|X3aoAvm= DC +*/ + +#ifndef _TREE_EDIT_H_ +#define _TREE_EDIT_H_ + +#include +#include + +#include "types.h" +#include "algebra.h" +#include "ppforestsz.h" +//#include "ppforestali.h" + +template +class Mapping +{ + R *m_mtrxTD; + R *m_mtrxFD; + Ulong *m_rowStartTD; + Ulong *m_rowStartFD; + Ulong m_mtrxSizeTD; + Ulong m_mtrxSizeFD; + R m_optimum; + + PPForestSZ *m_ppfx; + PPForestSZ *m_ppfy; + const SZAlgebra *m_alg; + + inline R getMtrxTDVal(Ulong i,Ulong j) const + { + assert(m_rowStartTD[i]+j &ppf,Uint i, Uint j, Uint k, Uint l, Uint &node); +public: + Mapping(const PPForestSZ *ppfx, const PPForestSZ *ppfy,const SZAlgebra &alg); + ~Mapping(); + + R getGlobalOptimum() {return m_optimum;}; +}; + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/treeedit.t.cpp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/treeedit.t.cpp new file mode 100755 index 00000000..f1f3a1f4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/treeedit.t.cpp @@ -0,0 +1,174 @@ +/* + Copyright by Matthias Hoechsmann (C) 2002-2003 + ===================================== + You may use, copy and distribute this file freely as long as you + - do not change the file, + - leave this copyright notice in the file, + - do not make any profit with the distribution of this file + - give credit where credit is due + You are not allowed to copy or distribute this file otherwise + The commercial usage and distribution of this file is prohibited + Please report bugs and suggestions to +*/ + +#ifndef _TREE_EDIT_T_CPP_ +#define _TREE_EDIT_T_CPP_ + +#include +#include + +#include "alignment.h" +#include "debug.h" + +#include "misc.t.cpp" +#include "ppforestsz.t.cpp" + +template +Mapping::Mapping(const PPForestSZ *ppfx, const PPForestSZ *ppfy, const SZAlgebra &alg) +{ + assert(ppfx != NULL); + assert(ppfy != NULL); + + Ulong m,n,h,cols; + Ulong i,j,k,l,r,s; + R score,h_score; + + + // alloc space for the score matrices + m=ppfx->size(); + n=ppfy->size(); + + m_mtrxSizeTD=(m)*(n); + m_mtrxSizeFD=(m+1)*(n+1); // +1 because index 0 means the empty forest + m_mtrxTD=new R[m_mtrxSizeTD]; + m_mtrxFD=new R[m_mtrxSizeFD]; + m_rowStartTD=new Ulong[m]; + m_rowStartFD=new Ulong[m+1]; + + m_ppfx = new PPForestSZ(*ppfx); + m_ppfy = new PPForestSZ(*ppfy); + m_alg=&alg; + + cols=n; + m_rowStartTD[0]=0; + for(h=1;hkeyroot(i)) + continue; + + for(j=0;jkeyroot(j)) + continue; + + // calculate forest distance + + // edit to empty forest + setMtrxFDVal(0,0,0); + + for(k=m_ppfx->lml(i),r=1;k<=i;k++,r++) // r is the indexpos of k + setMtrxFDVal(r,0,m_alg->del(m_ppfx->label(k),getMtrxFDVal(r-1,0))); + + for(l=m_ppfy->lml(j),s=1;l<=j;l++,s++) + setMtrxFDVal(0,s,m_alg->insert(getMtrxFDVal(0,s-1),m_ppfy->label(l))); // s is the indexpos of j + + for(k=m_ppfx->lml(i),r=1;k<=i;k++,r++) + { + for(l=m_ppfy->lml(j),s=1;l<=j;l++,s++) + { + // fdist(k,i,l,j) + // lml(k)==lml(i) && lml(l)==lml(j) + if(m_ppfx->lml(k)==m_ppfx->lml(i) && m_ppfy->lml(l)==m_ppfy->lml(j)) + { + score=m_alg->replace(m_ppfx->label(k),getMtrxFDVal(r-1,s-1),m_ppfy->label(l)); + + h_score=m_alg->del(m_ppfx->label(k),getMtrxFDVal(r-1,s)); + score=alg.choice(score,h_score); + + h_score=m_alg->insert(getMtrxFDVal(r,s-1),m_ppfy->label(l)); + score=alg.choice(score,h_score); + + setMtrxFDVal(r,s,score); + setMtrxTDVal(k,l,score); + } + else + { + long p,q; + p=m_ppfx->lml(k) - m_ppfx->lml(i); + q=m_ppfy->lml(l) - m_ppfy->lml(j); + + score=getMtrxFDVal(p,q) + getMtrxTDVal(k,l); + + h_score=m_alg->del(m_ppfx->label(k),getMtrxFDVal(r-1,s)); + score=alg.choice(score,h_score); + + h_score=m_alg->insert(getMtrxFDVal(r,s-1),m_ppfy->label(l)); + score=alg.choice(score,h_score); + + setMtrxFDVal(r,s,score); + } + } + } + } + } + + // until here the original tree edit distance was calculated + // to allow edit distances between forests, the distance for a virtual root node is calculated + // leftmost leaf of the root node is the first node in postorder traversal + // The distances are calculated until the last tree node in postorder traversal which then holds the result + // for a virtual root node that is matched with zero cost + + // edit to empty forest + setMtrxFDVal(0,0,0); + + for(k=0,r=1;kdel(m_ppfx->label(k),getMtrxFDVal(r-1,0))); + + for(l=0,s=1;linsert(getMtrxFDVal(0,s-1),m_ppfy->label(l))); // s is the indexpos of j + + for(k=0,r=1;klml(k); + q=m_ppfy->lml(l); + + score=getMtrxFDVal(p,q) + getMtrxTDVal(k,l); + + h_score=m_alg->del(m_ppfx->label(k),getMtrxFDVal(r-1,s)); + score=alg.choice(score,h_score); + + h_score=m_alg->insert(getMtrxFDVal(r,s-1),m_ppfy->label(l)); + score=alg.choice(score,h_score); + + setMtrxFDVal(r,s,score); + } + } + + m_optimum=getMtrxFDVal(m,n); +} + +template +Mapping::~Mapping() +{ + DELETE(m_ppfx); + DELETE(m_ppfy); + + delete[] m_mtrxTD; + delete[] m_mtrxFD; + delete[] m_rowStartTD; + delete[] m_rowStartFD; +} +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/types.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/types.h new file mode 100755 index 00000000..6cac73e7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/types.h @@ -0,0 +1,7 @@ +#ifndef _TYPES_H_ +#define _TYPES_H_ + +typedef unsigned int Uint; +typedef unsigned long Ulong; + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/unpairs.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/unpairs.c new file mode 100755 index 00000000..4ec6675b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/unpairs.c @@ -0,0 +1,112 @@ +#include "wmatch.h" + +/* Expands a blossom. Fixes up LINK and MATE. */ + +void UNPAIR (int oldbase, int oldmate) +{ int e, newbase, u; + +#ifdef DEBUG + printf("Unpair oldbase, oldmate=%d %d\n",oldbase, oldmate); +#endif + + UNLINK (oldbase); + newbase = BMATE (oldmate); + if (newbase != oldbase) { + LINK [oldbase] = -DUMMYEDGE; + REMATCH (newbase, MATE[oldbase]); + if (f == LASTEDGE[1]) + LINK[secondmate] = -LASTEDGE[2]; + else LINK[secondmate] = -LASTEDGE[1]; + } + e = LINK[oldmate]; + u = BEND (OPPEDGE (e)); + if (u == newbase) { + POINTER (newbase, oldmate, e); + return; + } + LINK[BMATE (u)] = -e; + do { + e = -LINK[u]; + v = BMATE (u); + POINTER (u, v, -LINK[v]); + u = BEND (e); + } while (u != newbase); + e = OPPEDGE (e); + POINTER (newbase, oldmate, e); +} + + +/* changes the matching along an alternating path */ +/* firstmate is the first base vertex on the path */ +/* edge e is the new matched edge for firstmate */ + +void REMATCH (int firstmate, int e) +{ +#ifdef DEBUG + printf("Rematch firstmate=%d e=%d-%d\n",firstmate, END[OPPEDGE(e)], END[e]); +#endif + + MATE[firstmate] = e; + nexte = -LINK[firstmate]; + while (nexte != DUMMYEDGE) { + e = nexte; + f = OPPEDGE (e); + firstmate = BEND (e); + secondmate = BEND (f); + nexte = -LINK[firstmate]; + LINK[firstmate] = -MATE[secondmate]; + LINK[secondmate] = -MATE[firstmate]; + MATE[firstmate] = f; + MATE[secondmate] = e; + } +} + + +/* unlinks subblossoms in a blossom. oldbase is the base of the blossom to */ +/* be unlinked. */ + +void UNLINK (int oldbase) +{ int k, j=1; + +#ifdef DEBUG + printf("Unlink oldbase=%d\n",oldbase); +#endif + + i = NEXTVTX[oldbase]; + newbase = NEXTVTX[oldbase]; + nextbase = NEXTVTX[LASTVTX[newbase]]; + e = LINK[nextbase]; +UL2: + do { + nextedge = OPPEDGE (LINK[newbase]); + for (k=1; k <= 2; ++k) { + LINK[newbase] = -LINK[newbase]; + BASE[i] = newbase; + i = NEXTVTX[i]; + while (i != nextbase) { + BASE[i] = newbase; + i = NEXTVTX[i]; + } + newbase = nextbase; + nextbase = NEXTVTX[LASTVTX[newbase]]; + } + } while (LINK[nextbase] == nextedge); + if (j==1) { + LASTEDGE[1] = nextedge; + j++; + nextedge = OPPEDGE (e); + if (LINK[nextbase] == nextedge) { + goto UL2; + } + } + LASTEDGE[2] = nextedge; + + if (BASE[LASTVTX[oldbase]] == oldbase) + NEXTVTX[oldbase] = newbase; + else { + NEXTVTX[oldbase] = DUMMYVERTEX; + LASTVTX[oldbase] = oldbase; + } +} + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/utils.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/utils.h new file mode 100755 index 00000000..402380ea --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/utils.h @@ -0,0 +1,52 @@ +#ifndef _UTILS_H_ +#define _UTILS_H_ + +// matthias : added naview_xy_coordinates to header +// removed extern's +// added ifndef +// added ectern "C" +// removed unsigned short xsubi[3]; from this file + +/* Header file for utils.c */ + +#if defined(__cplusplus) +extern "C" +{ +#endif + +int naview_xy_coordinates(short *pair_table, float *X, float *Y); +void *space(unsigned size); /* allocate space safely */ + +/*@exits@*/ +void nrerror(const char message[]); /* die with error message */ +void init_rand(void); /* make random number seeds */ + //unsigned short xsubi[3]; /* current 48bit random number */ +double urn(void); /* random number from [0..1] */ +int int_urn(int from, int to); /* random integer */ +void filecopy(FILE *from, FILE *to); /* inefficient `cp' */ +/*@observer@*/ +char *time_stamp(void); /* current date in a string */ +char *random_string(int l, const char symbols[]); +/* random string of length l using characters from symbols[] */ +int hamming(const char *s1, const char *s2); +/* calculate hamming distance */ +char *get_line(FILE *fp); /* read one (arbitrary length) line from fp */ + + +char *pack_structure(const char *struc); +/* pack secondary secondary structure, 5:1 compression using base 3 encoding */ +char *unpack_structure(const char *packed); +/* unpack sec structure packed with pack_structure() */ +short *make_pair_table(const char *structure); +/* returns a newly allocated table, such that: table[i]=j if (i.j) pair or + 0 if i is unpaired, table[0] contains the length of the structure. */ + +int bp_distance(const char *str1, const char *str2); +/* dist = {number of base pairs in one structure but not in the other} + same as edit distance with open-pair close-pair as move-set */ + +#if defined(__cplusplus) +} +#endif + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.c new file mode 100755 index 00000000..89ffe5c1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.c @@ -0,0 +1,147 @@ +/* N-cubed weighted matching */ +/* Implementation of H. Gabow's Ph.D. thesis, Stanford Univ. 1973 */ +/* Written by Edward Rothberg 7/85 */ +/* For complete details, please refer to the original paper */ + +/* Send either a Euclidean graph or an adjacency list graph. */ +/* Returns an array, the ith entry being the mate of vertex 'i'. */ +/* A zero entry indicates an unmatched vertex. */ + +/* To add new type, see readgraph.c */ + +#include "match.defs" +#include "graphtypes.h" +#include "wmatch.h" + +#include "pairs.c" +#include "pointer.c" +#include "readgraph.c" +#include "term.c" +#include "unpairs.c" + +void Initialize(int maximize); +void FreeUp(); + +int *Weighted_Match (void *gptr,int type,int maximize) + //int gptr,type,maximize; +{ int g, j, w, outcome; // loop=1; + + /* set up internal data structure */ + SetUp(gptr,type); + Initialize(maximize); + + for(;;) { + /* printf("Augment #%d\n",loop++); */ + DELTA = 0; + for (v=1; v<=U; ++v) + if (MATE[v] == DUMMYEDGE) + POINTER (DUMMYVERTEX, v, DUMMYEDGE); + for(;;) { + i = 1; + for (j=2; j<=U; ++j) + if (NEXT_D[i] > NEXT_D[j]) + i = j; + DELTA = NEXT_D[i]; + if (DELTA == LAST_D) + goto done; + v = BASE[i]; + if (LINK[v] >= 0) { + PAIR (&outcome); + if (outcome == 1) + break; + } + else { + w = BMATE (v); + if (LINK[w] < 0) { + POINTER (v, w, OPPEDGE(NEXTEDGE[i])); + } + else UNPAIR (v, w); + } + } + + LAST_D -=DELTA; + SET_BOUNDS(); + g = OPPEDGE(e); + REMATCH (BEND(e), g); + REMATCH (BEND(g), e); + } + +done: + SET_BOUNDS(); + UNPAIR_ALL(); + for (i=1; i<=U;++i) { + MATE[i] = END[MATE[i]]; + if (MATE[i]==DUMMYVERTEX) + MATE[i]=0; + } + + FreeUp(); + return(MATE); +} + + +void Initialize(int maximize) +{ int i, allocsize, max_wt= -MAXWT, min_wt=MAXWT; + + DUMMYVERTEX = U+1; + DUMMYEDGE = U+2*V+1; + END[DUMMYEDGE] = DUMMYVERTEX; + + for (i=U+2; i<=U+2*V; i+=2) { + if (WEIGHT[i] > max_wt) + max_wt = WEIGHT[i]; + if (WEIGHT[i] < min_wt) + min_wt = WEIGHT[i]; + } + if (!maximize) { + if (U%2!=0) { + printf("Must have an even number of vertices to do a\n"); + printf("minimum complete matching.\n"); + exit(0); + } + max_wt += 2; /* Don't want all zero weight */ + for (i=U+1; i<=U+2*V; i++) + WEIGHT[i] = max_wt-WEIGHT[i]; + max_wt = max_wt-min_wt; + } + LAST_D = max_wt/2; + + allocsize = (U+2)*sizeof(int); + MATE = (int *) malloc(allocsize); + LINK = (int *) malloc(allocsize); + BASE = (int *) malloc(allocsize); + NEXTVTX = (int *) malloc(allocsize); + LASTVTX = (int *) malloc(allocsize); + Y = (int *) malloc(allocsize); + NEXT_D = (int *) malloc(allocsize); + NEXTEDGE = (int *) malloc(allocsize); + allocsize = (U+2*V+2)*sizeof(int); + NEXTPAIR = (int *) malloc(allocsize); + + for (i = 1; i <= U+1; ++i) { + MATE[i] = DUMMYEDGE; + NEXTEDGE[i] = DUMMYEDGE; + NEXTVTX[i] = 0; + LINK[i] = -DUMMYEDGE; + BASE[i] = i; + LASTVTX[i] = i; + Y[i] = LAST_D; + NEXT_D[i] = LAST_D; + } +} + +void FreeUp() +{ + free(LINK); + free(BASE); + free(NEXTVTX); + free(LASTVTX); + free(Y); + free(NEXT_D); + free(NEXTEDGE); + free(NEXTPAIR); + free(A); + free(END); + free(WEIGHT); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.h new file mode 100755 index 00000000..62881b91 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.h @@ -0,0 +1,40 @@ +#ifndef _WMATCH_H_ +#define _WMATCH_H_ + +#ifdef __cplusplus +extern "C" +{ +#endif + + int *Weighted_Match (void *gptr,int type,int maximize); + + // pairs.c + void PAIR (int *outcome); + void MERGE_PAIRS (int v); + void LINK_PATH (int e); + void INSERT_PAIR (); + + // pointer.c + void POINTER (int u, int v, int e); + void SCAN (int x, int del); + + // readgraph.c + void SetUp (void* gptr, int type); + void SetStandard(Graph graph); + void SetEuclid(EuclidGraph graph); + void SetMatrix(MatrixGraph graph); + + // termc.c + void SET_BOUNDS (); + void UNPAIR_ALL (); + + // unpairs.c + void UNPAIR (int oldbase, int oldmate); + void REMATCH (int firstmate, int e) ; + void UNLINK (int oldbase); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/RNAforester/src/wmatch.o new file mode 100755 index 0000000000000000000000000000000000000000..78bdfcdf29fce7bfb4c5d5ffa3799efeef9c6a6a GIT binary patch literal 21896 zcmb7r3wTu3)%H1aPLe~IWI{*;HIXQYTtc`QB$I?oAOi#mBDsK;7?R8Y!H~pc27@Ie z5CR;I35i(5E9Q@_l-d?A)u6Q^AfUC1ij^v@w$grJ=x?-tk*`Jh-nI8SlLOyVpXZ;4 zoOi$bvi90*-_|-aH2LPwR#jE8KdPcB{Y+8%Zk8qK0!ArAl|;L$z#{Xni;D|d&bh53 z!F65>KiP5 zi{;*I9v>SqAK80UPwS6>Z8I-fMQ2QXTUQmBl}KXEgqAKstEkV?H=6DiOW!6-x~WnZ z^=~HLPfvYk7onBV(i<=H?Hs+uJeZZ38?GAqOv=nZV~iq77e=DJV%sCBtAqMVo=?xo!Y+v;kT!j%FtX7n&5|=#$*Dc6S#-Ls@QI5- z9Z%hISw*L62Vhp6!lc;Lue`X~-Y$Y#4#^~ebLCd}S^)H60$KShP`ue*3 z$TeeD;@LaMjG;Q_Z!PzBndQ~n*L`6nw0jQ*GpzhmrhB)QNZNH#eXFF;OcV_;&O|a- z*C;%^NgeAoGpVEHaFQ6Nd2FojjOjbsmfL>uyziuH`p$*Ytk5|t(h8l%Ol$g1tLQT; 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for config.h diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Formats b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Formats new file mode 100755 index 00000000..12830c82 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Formats @@ -0,0 +1,980 @@ +||||||||||| ReadSeq supported formats (revised 30Dec92) +-------------------------------------------------------- + + -f[ormat=]Name Format name for output: + 1. IG/Stanford 10. Olsen (in-only) + 2. GenBank/GB 11. Phylip3.2 + 3. NBRF 12. Phylip + 4. EMBL 13. Plain/Raw + 5. GCG 14. PIR/CODATA + 6. DNAStrider 15. MSF + 7. Fitch 16. ASN.1 + 8. Pearson/Fasta 17. PAUP + 9. Zuker (in-only) 18. Pretty (out-only) + +In general, output supports only minimal subsets of each format +needed for sequence data exchanges. Features, descriptions +and other format-unique information is discarded. + +Users of Olsen multi sequence editor (VMS). The Olsen format +here is produced with the print command: + print/out=some.file +Use Genbank output from readseq to produce a format that this +editor can read, and use the command + load/genbank some.file +Dan Davison has a VMS program that will convert to/from the +Olsen native binary data format. E-mail davison@uh.edu + +Warning: Phylip format input is now supported (30Dec92), however the +auto-detection of Phylip format is very probabilistic and messy, +especially distinguishing sequential from interleaved versions. It +is not recommended that one use readseq to convert files from Phylip +format to others unless essential. + + + +||||||||||| ReadSeq usage (revised 11Nov91) +-------------------------------------------------------- + +A. determine file format: + + short skiplines; /* result: number of header lines to skip (or 0) */ + short error; /* error result or 0 */ + short format; /* resulting format code, see ureadseq.h */ + char *filename = "Mysequence.file" + + format = seqFileFormat( filename, &skiplines, &error); + if (error!=0) fail; + +B. read number and list of sequences (optional) + short numseqs; /* resulting number of sequences found in file */ + char *seqlist; /* list of sequence names, newline separated, 0 terminated */ + + seqlist = listSeqs( filename, skiplines, format, &numseqs, &error); + if (error!=0) display (seqlist); + free( seqlist); + +C. read individual sequences as desired + short seqIndex; /* sequence index #, or == kListSeqs for listSeqs equivalent */ + long seqlen; /* length of seq */ + char seqid[256]; /* sequence name */ + char *seq; /* sequence, 0 terminated, free when done */ + + seq = readSeq( seqIndex, filename, skiplines, format, + &seqlen, &numseqs, &error, seqid); + if (error!=0) manipulate(seq); + free(seq); + +D. write sequences as desired + int nlines; /* number of lines of sequence written */ + FILE* fout; /* open file pointer (stdout or other) */ + short outform; /* output format, see ureadseq.h */ + + nlines = writeSeq( fout, seq, seqlen, format, outform, seqid); + + +Note (30Dec92): There is various processing done by the main program (in readseq.c), + rather than just in the subroutines (in ureadseq.c). Especially for interleaved + output formats, the writeSeq subroutine does not handle interleaving, nor some of + the formatting at the top and end of output files. While seqFileFormat, listSeqs, + and readSeq subroutines are fairly self-contained, the writeSeq depends a lot on + auxilliary processing. At some point, this may be revised so writeSeq is self- + contained. + +Note 2: The NCBI toolkit (ftp from ncbi.nlm.nih.gov) is needed for the ASN.1 format + reading (see ureadasn.c). A bastard (but workable I hope) ASN.1 format is written + by writeSeq alone. + + + +||||||||||| sequence formats.... +--------------------------------------------------- + +stanford/IG +;comments +;... +seq1 info +abcd... +efgh1 (or 2 = terminator) +;another seq +;.... +seq2 info +abcd...1 +--- for e.g. ---- +; Dro5s-T.Seq Length: 120 April 6, 1989 21:22 Check: 9487 .. +dro5stseq +GCCAACGACCAUACCACGCUGAAUACAUCGGUUCUCGUCCGAUCACCGAAAUUAAGCAGCGUCGCGGGCG +GUUAGUACUUAGAUGGGGGACCGCUUGGGAACACCGCGUGUUGUUGGCCU1 + +; TOIG of: Dro5srna.Seq check: 9487 from: 1 to: 120 +--------------------------------------------------- + +Genbank: +LOCUS seq1 ID.. +... +ORIGIN ... +123456789abcdefg....(1st 9 columns are formatting) + hijkl... +// (end of sequence) +LOCUS seq2 ID .. +... +ORIGIN + abcd... +// +--------------------------------------------------- + +NBRF format: (from uwgcg ToNBRF) +>DL;DRO5SRNA +Iubio$Dua0:[Gilbertd.Gcg]Dro5srna.Seq;2 => DRO5SRNA + + 51 AAUUAAGCAG CGUCGCGGGC GGUUAGUACU UAGAUGGGGG ACCGCUUGGG + 101 AACACCGCGU GUUGUUGGCC U + +--------------------------------------------------- + +EMBL format +ID345 seq1 id (the 345 are spaces) +... other info +SQ345Sequence (the 3,4,5 are spaces) +abcd... +hijk... +// (! this is proper end string: 12Oct90) +ID seq2 id +... +SQ Sequence +abcd... +... +// +--------------------------------------------------- + +UW GCG Format: +comments of any form, up to ".." signal +signal line has seq id, and " Check: #### .." +only 1 seq/file + +-- e.g. --- (GCG from GenBank) +LOCUS DROEST6 1819 bp ss-mRNA INV 31-AUG-1987 + ... much more ... +ORIGIN 1 bp upstream of EcoRI site; chromosome BK9 region 69A1. + +INVERTEBRATE:DROEST6 Length: 1819 January 9, 1989 16:48 Check: 8008 .. + + 1 GAATTCGCCG GAGTGAGGAG CAACATGAAC TACGTGGGAC TGGGACTTAT + + 51 CATTGTGCTG AGCTGCCTTT GGCTCGGTTC GAACGCGAGT GATACAGATG + + +--------------------------------------------------- + +DNAStrider (Mac) = modified Stanford: +; ### from DNA Strider Friday, April 7, 1989 11:04:24 PM +; DNA sequence pBR322 4363 b.p. complete sequence +; +abcd... +efgh +// (end of sequence) +--------------------------------------------------- + +Fitch format: +Dro5srna.Seq + GCC AAC GAC CAU ACC ACG CUG AAU ACA UCG GUU CUC GUC CGA UCA CCG AAA UUA AGC AGC + GUC GCG GGC GGU UAG UAC UUA GAU GGG GGA CCG CUU GGG AAC ACC GCG UGU UGU UGG CCU +Droest6.Seq + GAA TTC GCC GGA GTG AGG AGC AAC ATG AAC TAC GTG GGA CTG GGA CTT ATC ATT GTG CTG + AGC TGC CTT TGG CTC GGT TCG AAC GCG AGT GAT ACA GAT GAC CCT CTG TTG GTG CAG CTG +--------------------------------------------------- + +W.Pearson/Fasta format: +>BOVPRL GenBank entry BOVPRL from omam file. 907 nucleotides. +TGCTTGGCTGAGGAGCCATAGGACGAGAGCTTCCTGGTGAAGTGTGTTTCTTGAAATCAT + +--------------------------------------------------- +Phylip version 3.2 format (e.g., DNAML): + + 5 13 YF (# seqs, #bases, YF) +Alpha AACGTGGCCAAAT + aaaagggccc... (continued sp. alpha) +Beta AAGGTCGCCAAAC + aaaagggccc... (continued sp. beta) +Gamma CATTTCGTCACAA + aaaagggccc... (continued sp. Gamma) +1234567890^-- bases must start in col 11, and run 'til #bases + (spaces & newlines are okay) +--------------------------------------------------- +Phylip version 3.3 format (e.g., DNAML): + + 5 42 YF (# seqs, #bases, YF) +Turkey AAGCTNGGGC ATTTCAGGGT +Salmo gairAAGCCTTGGC AGTGCAGGGT +H. SapiensACCGGTTGGC CGTTCAGGGT +Chimp AAACCCTTGC CGTTACGCTT +Gorilla AAACCCTTGC CGGTACGCTT +1234567890^-- bases must start in col 11 + !! this version interleaves the species -- contrary to + all other output formats. + +GAGCCCGGGC AATACAGGGT AT +GAGCCGTGGC CGGGCACGGT AT +ACAGGTTGGC CGTTCAGGGT AA +AAACCGAGGC CGGGACACTC AT +AAACCATTGC CGGTACGCTT AA + +--------------------------------------------------- +Phylip version 3.4 format (e.g., DNAML) +-- Both Interleaved and sequential are permitted + + 5 13 (# seqs, #bases) +Alpha AACGTGGCCAAAT + aaaagggccc... (continued sp. alpha) +Beta AAGGTCGCCAAAC + aaaagggccc... (continued sp. beta) +Gamma CATTTCGTCACAA + aaaagggccc... (continued sp. Gamma) +1234567890^-- bases must start in col 11, and run 'til #bases + (spaces, newlines and numbers are are ignored) + +--------------------------------------------------- +Gary Olsen (multiple) sequence editor /print format: + +!--------------------- +!17Oct91 -- error in original copy of olsen /print format, shifted right 1 space +! here is correct copy: + 301 40 Tb.thiop CGCAGCGAAA----------GCUNUGCUAAUACCGCAUA-CGnCCUG----------------------------------------------------- Tb.thiop +123456789012345678901 + 301 42 Rhc.purp CGUAGCGAAA----------GUUACGCUAAUACCGCAUA-UUCUGUG----------------------------------------------------- Rhc.purp + + 301 44 Rhc.gela nnngnCGAAA----------GCCGGAUUAAUACCGCAUA-CGACCUA----------------------------------------------------- Rhc.gela +!--------------------- + + RNase P RNA components. on 20-FEB-90 17:23:58 + + 1 (E.c. pr ): Base pairing in Escherichia coli RNase P RNA. + 2 (chrom ): Chromatium + : + 12 (B.brevis): Bacillus brevis RNase P RNA, B. James. + 13 ( 90% con): 90% conserved + 14 (100% con): 100% conserved + 15 (gram+ pr): pairing + +1 + RNase P RNA components. on 20-FEB-90 17:23:58 + + Posi- Sequence + tion: identity: Data: + + 1 1 E.c. pr <<<<<<<<<< {{{{{{{{<<:<<<<<<<<<<^<<<<<<====>>>> E.c. pr + 1 2 chrom GGAGUCGGCCAGACAGUCGCUUCCGUCCU------------------ chrom + : + 1 12 B.brevis AUGCAGGAAAUGCGGGUAGCCGCUGCCGCAAUCGUCU------------- B.brevis +1234567890123456789012 >>>>>^>>^>>>>:>> <<<^<<<< {{{{{ E.c. pr + 60 2 chrom -----GGUG-ACGGGGGAGGAAAGUCCGG-GCUCCAU------------- chrom + : : + 60 10 B.stearo ----UU-CG-GCCGUAGAGGAAAGUCCAUGCUCGCACGGUGCUGAGAUGC B.stearo + + +--------------------------------------------------- + GCG MSF format +Title line + +picorna.msf MSF: 100 Type: P January 17, 1991 17:53 Check: 541 +.. +Name: Cb3 Len: 100 Check: 7009 Weight: 1.00 +Name: E Len: 100 Check: 60 Weight: 1.00 + +// + + 1 50 +Cb3 ...gpvedai .......t.. aaigr..vad tvgtgptnse aipaltaaet + E gvenae.kgv tentna.tad fvaqpvylpe .nqt...... kv.affynrs + + 51 100 + +Cb3 ghtsqvvpgd tmqtrhvkny hsrsestien flcrsacvyf teykn..... + E ...spi.gaf tvks...... gs.lesgfap .fsngtc.pn sviltpgpqf + +--------------------------------------------------- + PIR format +This is NBRF-PIR MAILSERVER version 1.45 +Command-> get PIR3:A31391 +\\\ +ENTRY A31391 #Type Protein +TITLE *Esterase-6 - Fruit fly (Drosophila melanogaster) + +DATE 03-Aug-1992 #Sequence 03-Aug-1992 #Text 03-Aug-1992 +PLACEMENT 0.0 0.0 0.0 0.0 0.0 +COMMENT *This entry is not verified. +SOURCE Drosophila melanogaster + +REFERENCE + #Authors Cooke P.H., Oakeshott J.G. + #Citation submitted to GenBank, April 1989 + #Reference-number A31391 + #Accession A31391 + #Cross-reference GB:J04167 + +SUMMARY #Molecular-weight 61125 #Length 544 #Checksum 1679 +SEQUENCE + 5 10 15 20 25 30 + 1 M N Y V G L G L I I V L S C L W L G S N A S D T D D P L L V + 31 Q L P Q G K L R G R D N G S Y Y S Y E S I P Y A E P P T G D + 61 L R F E A P E P Y K Q K W S D I F D A T K T P V A C L Q W D + 91 Q F T P G A N K L V G E E D C L T V S V Y K P K N S K R N S + 121 F P V V A H I H G G A F M F G A A W Q N G H E N V M R E G K + 151 F I L V K I S Y R L G P L G F V S T G D R D L P G N Y G L K + 181 D Q R L A L K W I K Q N I A S F G G E P Q N V L L V G H S A + 211 G G A S V H L Q M L R E D F G Q L A R A A F S F S G N A L D + 241 P W V I Q K G A R G R A F E L G R N V G C E S A E D S T S L + 271 K K C L K S K P A S E L V T A V R K F L I F S Y V P F A P F + 301 S P V L E P S D A P D A I I T Q D P R D V I K S G K F G Q V + 331 P W A V S Y V T E D G G Y N A A L L L K E R K S G I V I D D + 361 L N E R W L E L A P Y L L F Y R D T K T K K D M D D Y S R K + 391 I K Q E Y I G N Q R F D I E S Y S E L Q R L F T D I L F K N + 421 S T Q E S L D L H R K Y G K S P A Y A Y V Y D N P A E K G I + 451 A Q V L A N R T D Y D F G T V H G D D Y F L I F E N F V R D + 481 V E M R P D E Q I I S R N F I N M L A D F A S S D N G S L K + 511 Y G E C D F K D N V G S E K F Q L L A I Y I D G C Q N R Q H + 541 V E F P +/// +\\\ +--------------------------------------------------- +PAUP format: +The NEXUS Format + +Every block starts with "BEGIN blockname;" and ends with "END;". +Each block is composed of one or more statements, each +terminated by a semicolon (;). + +Comments may be included in NEXUS files by enclosing them within +square brackets, as in "[This is a comment]." + +NEXUS-conforming files are identified by a "#NEXUS" directive at +the very beginning of the file (line 1, column 1). If the +#NEXUS is omitted PAUP issues a warning but continues +processing. + +NEXUS files are entirely free-format. Blanks, tabs, and +newlines may be placed anywhere in the file. Unless RESPECTCASE +is requested, commands and data may be entered in upper case, +lower case, or a mixture of upper and lower case. + +The following conventions are used in the syntax descriptions of +the various blocks. Upper-case items are entered exactly as +shown. Lower-case items inside of angle brackets -- e.g., +-- represent items to be substituted by the user. Items inside +of square brackets -- e.g., [X] -- are optional. Items inside +of curly braces and separated by vertical bars -- e.g., { X | Y +| Z } -- are mutually exclusive options. + + +The DATA Block + +The DATA block contains the data matrix and other associated +information. Its syntax is: + +BEGIN DATA; +DIMENSIONS NTAX= NCHAR=; + [ FORMAT [ MISSING= ] + [ LABELPOS={ LEFT | RIGHT } ] + [ SYMBOLS="" ] + [ INTERLEAVE ] + [ MATCHCHAR= ] + [ EQUATE="= [=...]" ] + [ TRANSPOSE ] + [ RESPECTCASE ] + [ DATATYPE = { STANDARD | DNA | RNA | PROTEIN } ]; ] + [ OPTIONS [ IGNORE={ INVAR | UNINFORM } ] + [ MSTAXA = { UNCERTAIN | POLYMORPH | VARIABLE } ] + [ ZAP = "" ] ; ] + [ CHARLABELS label_2>ÊÉ ; ] + [ TAXLABELS ; ] + [ STATELABELS ; ] + MATRIX ; + END; + +--- example PAUP file + +#NEXUS + +[!Brown et al. (1982) primate mitochondrial DNA] + +begin data; + dimensions ntax=5 nchar=896; + format datatype=dna matchchar=. interleave missing='-'; + matrix +[ 2 4 6 8 ] +[ 1 1 1 1 1 ] +human aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcctcattactatt ctgcctagcaaactcaaact acgaacgcactcacagtcgc +chimp ................a.t. .c.................a ...............t.... ..................t. .t........c......... +gorilla ..................tg ....t.....t........a ........a......t.... .................... .......a..c.....c... +orang ................ac.. cc.....g..t.....t..a ..c........cc....g.. .................... .......a..c.....c... +gibbon ......t..a..t...ac.g .c.................a ..a..c..t..cc.g..... ......t............. .......a........c... + +[ 8 8 8 8 8 8 ] +[ 0 2 4 6 8 9 ] +[ 1 1 1 1 1 6 ] +human cttccccacaacaatattca tgtgcctagaccaagaagtt attatctcgaactgacactg agccacaacccaaacaaccc agctctccctaagctt +chimp t................... .a................c. ........a.....g..... ...a................ ................ +gorilla ..................tc .a................c. ........a.g......... ...a.............tt. .a.............. +orang ta....a...........t. .c.......ga......acc ..cg..a.a......tg... .a.a..c.....g...cta. .a.....a........ +gibbon a..t.......t........ ....ac...........acc .....t..a........... .a.tg..........gctag .a.............. + ; +end; +--------------------------------------------------- + + + + + + +||||||||||| Sample SMTP mail header +--------------------------------------------------- + +- - - - - - - - - +From GenBank-Retrieval-System@genbank.bio.net Sun Nov 10 17:28:56 1991 +Received: from genbank.bio.net by sunflower.bio.indiana.edu + (4.1/9.5jsm) id AA19328; Sun, 10 Nov 91 17:28:55 EST +Received: by genbank.bio.net (5.65/IG-2.0) + id AA14458; Sun, 10 Nov 91 14:30:03 -0800 +Date: Sun, 10 Nov 91 14:30:03 -0800 +Message-Id: <9111102230.AA14458@genbank.bio.net> +From: Database Server +To: gilbertd@sunflower.bio.indiana.edu +Subject: Results of Query for drorna +Status: R + +No matches on drorna. +- - - - - - +From GenBank-Retrieval-System@genbank.bio.net Sun Nov 10 17:28:49 1991 +Received: from genbank.bio.net by sunflower.bio.indiana.edu + (4.1/9.5jsm) id AA19323; Sun, 10 Nov 91 17:28:47 EST +Received: by genbank.bio.net (5.65/IG-2.0) + id AA14461; Sun, 10 Nov 91 14:30:03 -0800 +Date: Sun, 10 Nov 91 14:30:03 -0800 +Message-Id: <9111102230.AA14461@genbank.bio.net> +From: Database Server +To: gilbertd@sunflower.bio.indiana.edu +Subject: Results of Query for droest6 +Status: R + +LOCUS DROEST6 1819 bp ss-mRNA INV 31-AUG-1987 +DEFINITION D.melanogaster esterase-6 mRNA, complete cds. +ACCESSION M15961 + + + + + + + + + + + + +||||||||||| GCG manual discussion of sequence symbols: +--------------------------------------------------- + +III_SEQUENCE_SYMBOLS + + + GCG programs allow all upper and lower case letters, periods (.), +asterisks (*), pluses (+), ampersands (&), and ats (@) as symbols in +biological sequences. Nucleotide symbols, their complements, and the +standard one-letter amino acid symbols are shown below in separate lists. +The meanings of the symbols +, &, and @ have not been assigned at this +writing (March, 1989). + + GCG uses the letter codes for amino acid codes and nucleotide +ambiguity proposed by IUB (Nomenclature Committee, 1985, +Eur. J. Biochem. 150; 1-5). These codes are compatible with the codes +used by the EMBL, GenBank, and NBRF data libraries. + + + NUCLEOTIDES + + The meaning of each symbol, its complement, and the Cambridge and +Stanford equivalents are shown below. Cambridge files can be converted +into GCG files and vice versa with the programs FROMSTADEN and TOSTADEN. +IntelliGenetics sequence files can be interconverted with the programs +FROMIG and TOIG. + +IUB/GCG Meaning Complement Staden/Sanger Stanford + + A A T A A + C C G C C + G G C G G + T/U T A T T/U + M A or C K 5 J + R A or G Y R R + W A or T W 7 L + S C or G S 8 M + Y C or T R Y Y + K G or T M 6 K + V A or C or G B not supported N + H A or C or T D not supported N + D A or G or T H not supported N + B C or G or T V not supported N + X/N G or A or T or C X -/X N + . not G or A or T or C . not supported ? + + + The frame ambiguity codes used by Staden are not supported by GCG +and are translated by FROMSTADEN as the lower case single base +equivalent. + + Staden Code Meaning GCG + + D C or CC c + V T or TT t + B A or AA a + H G or GG g + K C or CX c + L T or TX t + M A or AX a + N G or GX g + + + AMINO ACIDS + + Here is a list of the standard one-letter amino acid codes and their +three-letter equivalents. The synonymous codons and their depiction in +the IUB codes are shown. You should recognize that the codons following +semicolons (;) are not sufficiently specific to define a single amino +acid even though they represent the best possible back translation into +the IUB codes! All of the relationships in this list can be redefined by +the user in a local data file described below. + + IUB +Symbol 3-letter Meaning Codons Depiction + A Ala Alanine GCT,GCC,GCA,GCG !GCX + B Asp,Asn Aspartic, + Asparagine GAT,GAC,AAT,AAC !RAY + C Cys Cysteine TGT,TGC !TGY + D Asp Aspartic GAT,GAC !GAY + E Glu Glutamic GAA,GAG !GAR + F Phe Phenylalanine TTT,TTC !TTY + G Gly Glycine GGT,GGC,GGA,GGG !GGX + H His Histidine CAT,CAC !CAY + I Ile Isoleucine ATT,ATC,ATA !ATH + K Lys Lysine AAA,AAG !AAR + L Leu Leucine TTG,TTA,CTT,CTC,CTA,CTG +!TTR,CTX,YTR;YTX + M Met Methionine ATG !ATG + N Asn Asparagine AAT,AAC !AAY + P Pro Proline CCT,CCC,CCA,CCG !CCX + Q Gln Glutamine CAA,CAG !CAR + R Arg Arginine CGT,CGC,CGA,CGG,AGA,AGG +!CGX,AGR,MGR;MGX + S Ser Serine TCT,TCC,TCA,TCG,AGT,AGC !TCX,AGY;WSX + T Thr Threonine ACT,ACC,ACA,ACG !ACX + V Val Valine GTT,GTC,GTA,GTG !GTX + W Trp Tryptophan TGG !TGG + X Xxx Unknown !XXX + Y Tyr Tyrosine TAT, TAC !TAY + Z Glu,Gln Glutamic, + Glutamine GAA,GAG,CAA,CAG !SAR + * End Terminator TAA, TAG, TGA !TAR,TRA;TRR + + + + + + + + +||||||||||| docs from PSC on sequence formats: +--------------------------------------------------- + + + Nucleic Acid and Protein Sequence File Formats + + +It will probably save you some time if you have your data in a usable +format before you send it to us. However, we do have the University of +Wisconsin Genetics Computing Group programs running on our VAXen and +this package includes several reformatting utilities. Our programs +usually recognize any of several standard formats, including GenBank, +EMBL, NBRF, and MolGen/Stanford. For the purposes of annotating an +analysis we find the GenBank and EMBL formats most useful, particularly +if you have already received an accession number from one of these +organizations for your sequence. + +Our programs do not require that all of the line types available in +GenBank, EMBL, or NBRF file formats be present for the file format to +be recognized and processed. The following pages outline the essential +details required for correct processing of files by our programs. +Additional information may be present but will generally be ignored. + + + GenBank File Format + +File Header + +1. The first line in the file must have "GENETIC SEQUENCE DATA BANK" + in spaces 20 through 46 (see LINE 1, below). +2. The next 8 lines may contain arbitrary text. They are ignored but + are required to maintain the GenBank format (see LINE 2 - LINE 9). + +Sequence Data Entries + +3. Each sequence entry in the file should have the following format. + a) first line: Must have LOCUS in the first 5 spaces. The + genetic locus name or identifier must be in spaces + 13 - 22. The length of the sequences is right + justified in spaces 23 through 29 (see LINE 10). + b) second line: Must have DEFINITION in the first 10 spaces. + Spaces 13 - 80 are free form text to identify the + sequence (see LINE 11). + c) third line: Must have ACCESSION in the first 9 spaces. Spaces + 13 - 18 must hold the primary accession number + (see LINE 12). + d) fourth line: Must have ORIGIN in the first 6 spaces. Nothing + else is required on this line, it indicates that + the nucleic acid sequence begins on the next line + (see LINE 13). + e) fifth line: Begins the nucleotide sequence. The first 9 + spaces of each sequence line may either be blank + or may contain the position in the sequence of the + first nucleotide on the line. The next 66 spaces + hold the nucleotide sequence in six blocks of ten + nucleotides. Each of the six blocks begins with a + blank space followed by ten nucleotides. Thus the + first nucleotide is in space eleven of the line while + the last is in space 75 (see LINE 14, LINE 15). + f) last line: Must have // in the first 2 spaces to indicate + termination of the sequence (see LINE 16). + +NOTE: Multiple sequences may appear in each file. To begin another + sequence go back to a) and start again. + + + Example GenBank file + + +LINE 1 : GENETIC SEQUENCE DATA BANK +LINE 2 : +LINE 3 : +LINE 4 : +LINE 5 : +LINE 6 : +LINE 7 : +LINE 8 : +LINE 9 : +LINE 10 :LOCUS L_Name Length BP +LINE 11 :DEFINITION Describe the sequence any way you want +LINE 12 :ACCESSION Accession Number +LINE 13 :ORIGIN +LINE 14 : 1 acgtacgtac gtacgtacgt acgtacgtac gtacgtacgt a... +LINE 15 : 61 acgt... +LINE 16 :// + + + + EMBL File Format + +Unlike the GenBank file format the EMBL file format does not require +a series of header lines. Thus the first line in the file begins +the first sequence entry of the file. + +1. The first line of each sequence entry contains the two letters ID + in the first two spaces. This is followed by the EMBL identifier + in spaces 6 through 14. (See LINE 1). + +2. The second line of each sequence entry has the two letters AC in + the first two spaces. This is followed by the accession number in + spaces 6 through 11. (See LINE 2). + +3. The third line of each sequence entry has the two letters DE in the + first two spaces. This is followed by a free form text definition + in spaces 6 through 72. (See LINE 3). + +4. The fourth line in each sequence entry has the two letters SQ in + the first two spaces. This is followed by the length of the + sequence beginning at or after space 13. After the sequence length + there is a blank space and the two letters BP. (See LINE 4). + +5. The nucleotide sequence begins on the fifth line of the sequence + entry. Each line of sequence begins with four blank spaces. The + next 66 spaces hold the nucleotide sequence in six blocks of ten + nucleotides. Each of the six blocks begins with a blank space + followed by ten nucleotides. Thus the first nucleotide is in space + 6 of the line while the last is in space 70. (See LINE 5 - + LINE 6). + +6. The last line of each sequence entry in the file is a terminator + line which has the two characters // in the first two spaces. + (See LINE 7). + +7. Multiple sequences may appear in each file. To begin another + sequence go back to item 1 and start again. + + + Example EMBL file + +LINE 1 :ID ID_name +LINE 2 :AC Accession number +LINE 3 :DE Describe the sequence any way you want +LINE 4 :SQ Length BP +LINE 5 : ACGTACGTAC GTACGTACGT ACGTACGTAC GTACGTA... +LINE 6 : ACGT... +LINE 7 :// + + + + NBRF (protein or nucleic acid) File Format + +1. The first line of each sequence entry begins with a greater than + symbol, >. This is immediately followed by the two character + sequence type specifier. Space four must contain a semi-colon. + Beginning in space five is the sequence name or identification code + for the NBRF database. The code is from four to six letters and + numbers. (See LINE 1). + +!!!! >> add these to readseq + Specifier Sequence type + + P1 protein, complete + F1 protein, fragment + DL DNA, linear + DC DNA, circular + RL RNA, linear + RC RNA, circular + N1 functional RNA, other than tRNA + N3 tRNA + +2. The second line of each sequence entry contains two kinds of + information. First is the sequence name which is separated from + the organism or organelle name by the three character sequence + blank space, dash, blank space, " - ". There is no special + character marking the beginning of this line. (See LINE 2). + +3. Either the amino acid or nucleic acid sequence begins on line three + and can begin in any space, including the first. The sequence is + free format and may be interrupted by blanks for ease of reading. + Protein sequences man contain special punctuation to indicate + various indeterminacies in the sequence. In the NBRF data files + all lines may be up to 500 characters long. However some PSC + programs currently have a limit of 130 characters per line + (including blanks), and BitNet will not accept lines of over eighty + characters. (See LINE 3, LINE 4, and LINE 5). + + The last character in the sequence must be an asterisks, *. + + Example NBRF file + + LINE 1 :>P1;CBRT + LINE 2 :Cytochrome b - Rat mitochondrion (SGC1) + LINE 3 :M T N I R K S H P L F K I I N H S F I D L P A P S + LINE 4 : VTHICRDVN Y GWL IRY + LINE 5 :TWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIVEDKMLKWN* + + + + MolGen/Stanford File Format + +1. The first line in a sequence file is a comment line. This line + begins with a semi-colon in the first space. This line need + not be present. If it is present it holds descriptive text. + There may be as many comment lines as desired at the first of + sequence file. (See LINE 1). + +2. The second line must be present and contains an identifier or + name for the sequence in the first ten spaces. (See LINE 2). + +3. The sequence begins on the third line and occupies up to eighty + spaces. Spaces may be included in the sequence for ease of + reading. The sequence continues for as many line as needed + and is terminated with a 1 or 2. 1 indicates a linear sequence + while 2 marks a circular sequence. (See LINE 3 and LINE 4). + + Example MolGen/Stanford file + +LINE 1 :; Describe the sequence any way you want +LINE 2 :ECTRNAGLY2 +LINE 3 :ACGCACGTAC ACGTACGTAC A C G T C C G T ACG TAC GTA CGT +LINE 4 : GCTTA GG G C T A1 + + + + +||||||||||| Phylip file format +--------------------------------------------------- + + Phylip 3.3 File Format (DNA sequences) + + + The input and output formats for PROTPARS and for RESTML are described in +their document files. In general their input formats are similar to those +described here, except that the one-letter codes for data are specific to those +programs and are described in those document files. Since the input formats +for the eight DNA sequence programs apply to all eight, they are described +here. Their input formats are standard: the data have A's, G's, C's and T's +(or U's). The first line of the input file contains the number of species and +the number of sites. As with the other programs, options information may +follow this. In the case of DNAML, DNAMLK, and DNADIST an additional line +(described in the document file for these pograms) may follow the first one. +Following this, each species starts on a new line. The first 10 characters of +that line are the species name. There then follows the base sequence of that +species, each character being one of the letters A, B, C, D, G, H, K, M, N, O, +R, S, T, U, V, W, X, Y, ?, or - (a period was also previously allowed but it is +no longer allowed, because it sometimes is used to in aligned sequences to mean +"the same as the sequence above"). Blanks will be ignored, and so will +numerical digits. This allows GENBANK and EMBL sequence entries to be read +with minimum editing. + + These characters can be either upper or lower case. The algorithms +convert all input characters to upper case (which is how they are treated). +The characters constitute the IUPAC (IUB) nucleic acid code plus some slight +extensions. They enable input of nucleic acid sequences taking full account of +any ambiguities in the sequence. + +The sequences can continue over multiple lines; when this is done the sequences +must be either in "interleaved" format, similar to the output of alignment +programs, or "sequential" format. These are described in the main document +file. In sequential format all of one sequence is given, possibly on multiple +lines, before the next starts. In interleaved format the first part of the +file should contain the first part of each of the sequences, then possibly a +line containing nothing but a carriage-return character, then the second part +of each sequence, and so on. Only the first parts of the sequences should be +preceded by names. Here is a hypothetical example of interleaved format: + + 5 42 +Turkey AAGCTNGGGC ATTTCAGGGT +Salmo gairAAGCCTTGGC AGTGCAGGGT +H. SapiensACCGGTTGGC CGTTCAGGGT +Chimp AAACCCTTGC CGTTACGCTT +Gorilla AAACCCTTGC CGGTACGCTT + +GAGCCCGGGC AATACAGGGT AT +GAGCCGTGGC CGGGCACGGT AT +ACAGGTTGGC CGTTCAGGGT AA +AAACCGAGGC CGGGACACTC AT +AAACCATTGC CGGTACGCTT AA + +while in sequential format the same sequences would be: + + 5 42 +Turkey AAGCTNGGGC ATTTCAGGGT +GAGCCCGGGC AATACAGGGT AT +Salmo gairAAGCCTTGGC AGTGCAGGGT +GAGCCGTGGC CGGGCACGGT AT +H. SapiensACCGGTTGGC CGTTCAGGGT +ACAGGTTGGC CGTTCAGGGT AA +Chimp AAACCCTTGC CGTTACGCTT +AAACCGAGGC CGGGACACTC AT +Gorilla AAACCCTTGC CGGTACGCTT +AAACCATTGC CGGTACGCTT AA + + +Note, of course, that a portion of a sequence like this: + + 300 AAGCGTGAAC GTTGTACTAA TRCAG + +is perfectly legal, assuming that the species name has gone before, and is +filled out to full length by blanks. The above digits and blanks will be +ignored, the sequence being taken as starting at the first base symbol (in this +case an A). + + The present versions of the programs may sometimes have difficulties with +the blank lines between groups of lines, and if so you might want to retype +those lines, making sure that they have only a carriage-return and no blank +characters on them, or you may perhaps have to eliminate them. The symptoms of +this problem are that the programs complain that the sequences are not properly +aligned, and you can find no other cause for this complaint. + +------------------------------------------------ + + +||||||||||| ASN.1 file format +--------------------------------------------------- + + +ASN.1 -- see NCBI toolkit docs, source and examples (ncbi.nlm.nih.gov) + +Example asn.1 sequence file---- + +Bioseq-set ::= { +seq-set { + seq { + id { local id 1 } , -- id essential + descr { title "Dummy sequence data from nowhere" } , -- optional + inst { -- inst essential + repr raw , + mol dna , + length 156 , + topology linear , + seq-data + iupacna "GAATTCATTTTTGAAACAAATCGACCTGACGACGGAATGGTACTCGAATTA +TGGGCCAAAGGGTTTTATGGGACAAATTAATAGGTGTTCATTATATGCCACTTTCGGAGATTAGATACAGCAATGCAG +TGGATTCAAAGCAATAGAGTTGTTCTT" + } } , + + seq { + id { local id 2 } , + descr { title "Dummy sequence 2 data from somewhere else" } , + inst { + repr raw , + mol dna , + length 150 , + topology linear , + seq-data + iupacna "TTTTTTTTTTTTGAAACAAATCGACCTGACGACGGAATGGTACTCGAATTA +TGGGCCAAAGGGTTTTATGGGACAAATTAATAGGTGTTCATTATATGCCACTTTCGGAGATTAGATACAGCAATGCAG +TGGATTCAAAGCAATAGAGTT" + } + } + } + } + + +partial ASN.1 description from toolkit + +Bioseq ::= SEQUENCE { + id SET OF Seq-id , -- equivalent identifiers + descr Seq-descr OPTIONAL , -- descriptors + inst Seq-inst , -- the sequence data + annot SET OF Seq-annot OPTIONAL } + +Seq-inst ::= SEQUENCE { -- the sequence data itself + repr ENUMERATED { -- representation class + not-set (0) , -- empty + virtual (1) , -- no seq data + raw (2) , -- continuous sequence + seg (3) , -- segmented sequence + const (4) , -- constructed sequence + ref (5) , -- reference to another sequence + consen (6) , -- consensus sequence or pattern + map (7) , -- ordered map (genetic, restriction) + other (255) } , + mol ENUMERATED { -- molecule class in living organism + not-set (0) , -- > cdna = rna + dna (1) , + rna (2) , + aa (3) , + na (4) , -- just a nucleic acid + other (255) } , + length INTEGER OPTIONAL , -- length of sequence in residues + fuzz Int-fuzz OPTIONAL , -- length uncertainty + topology ENUMERATED { -- topology of molecule + not-set (0) , + linear (1) , + circular (2) , + tandem (3) , -- some part of tandem repeat + other (255) } DEFAULT linear , + strand ENUMERATED { -- strandedness in living organism + not-set (0) , + ss (1) , -- single strand + ds (2) , -- double strand + mixed (3) , + other (255) } OPTIONAL , -- default ds for DNA, ss for RNA, pept + seq-data Seq-data OPTIONAL , -- the sequence + ext Seq-ext OPTIONAL , -- extensions for special types + hist Seq-hist OPTIONAL } -- sequence history + +------------------------------------------------ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.com b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.com new file mode 100755 index 00000000..82da18a5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.com @@ -0,0 +1,63 @@ +$! +$!VAX-VMS cc make file for readseq +$! +$ echo := write sys$output +$ if p1.eqs."TEST" then goto tests +$ +$ echo "compiling readseq..." +$ cc readseq, ureadseq +$! +$ echo "linking readseq..." +$ link readseq, ureadseq, sys$library:vaxcrtl/lib +$! +$tests: +$! +$ echo "defining readseq symbol:" +$ dd = f$environment("default") +$ readseq :== $ 'dd'readseq.exe +$ show symbol readseq +$! +$ echo "" +$ echo "test for general read/write of all chars:" +$ readseq -p alphabet.std -otest.alpha +$ diff test.alpha alphabet.std +$! +$ echo "" +$ echo "test for valid format conversions" +$! +$ readseq -v -p -f=ig nucleic.std -otest.ig +$ readseq -v -p -f=gb test.ig -otest.gb +$ readseq -v -p -f=nbrf test.gb -otest.nbrf +$ readseq -v -p -f=embl test.nbrf -otest.embl +$ readseq -v -p -f=gcg test.embl -otest.gcg +$ readseq -v -p -f=strider test.gcg -otest.strider +$ readseq -v -p -f=fitch test.strider -otest.fitch +$ readseq -v -p -f=fasta test.fitch -otest.fasta +$ readseq -v -p -f=pir test.fasta -otest.pir +$ readseq -v -p -f=ig test.pir -otest.ig-b +$ diff test.ig test.ig-b +$! +$ echo "" +$ echo "Test for multiple-sequence format conversions:" +$ readseq -p -f=ig multi.std -otest.m-ig +$ readseq -p -f=gb test.m-ig -otest.m-gb +$ readseq -p -f=nbrf test.m-gb -otest.m-nbrf +$ readseq -p -f=embl test.m-nbrf -otest.m-embl +$ readseq -p -f=fasta test.m-embl -otest.m-fasta +$ readseq -p -f=pir test.m-fasta -otest.m-pir +$ readseq -p -f=msf test.m-pir -otest.m-msf +$ readseq -p -f=paup test.m-msf -otest.m-paup +$ readseq -p -f=ig test.m-paup -otest.m-ig-b +$ diff test.m-ig test.m-ig-b +$ echo "" +$ echo "Expect differences in the header lines due to" +$ echo "different format headers. If any sequence lines" +$ echo "differ, or if checksums differ, there is a problem." +$! +$! #cleanup +$! delete test.*; +$ echo "-----------" +$ echo "" +$ echo "To clean up test files, command me: +$ echo " DELETE test.*;" +$! diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.ncbi b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.ncbi new file mode 100755 index 00000000..f6df5af6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Make.ncbi @@ -0,0 +1,110 @@ +# +# Unix Makefile for readseq +# to use, command me: +# % make -- or -- +# % make CC=your-c-compiler-name +# + +# pick an ANSI C compiler (the default Sun CC is not ANSI) +CC=gcc # Gnu C Compiler +#CC=cc # SGI Irix +#CC=vcc # some DEC Ultrix + +CFLAGS= +#CFLAGS= -DSMALLCHECKSUM # if you prefer to use a GCG-standard 13 bit checksum +# instead of a full 32 bit checksum. This may enhance compatibility w/ GCG software + +SOURCES= readseq.c ureadseq.c ureadseq.h ureadasn.c +DOCS= Readme readseq.help Formats Stdfiles Makefile Make.com add.gdemenu *.std + + +# NCBI toolkit support for ASN.1 reader + +# this is path to NCBI toolkit, you must set for your system: +NCBI=/bio/mb/ncbi +# +OTHERLIBS=-lm +LIB1=-lncbi +LIB2=-lncbiobj +LIB3=-lncbicdr +LIB4=-lvibrant +INCPATH=$(NCBI)/include +LIBPATH=$(NCBI)/lib +NCFLAGS=$(CFLAGS) -DNCBI -I$(INCPATH) +NLDFLAGS=-I$(INCPATH) -L$(LIBPATH) +NLIBS=$(LIB1) $(LIB2) $(OTHERLIBS) + + +all: build test + +#build: $(SOURCES) +# @echo "Compiling readseq..." +# $(CC) $(CFLAGS) -o readseq readseq.c ureadseq.c + +# if using NCBI, uncomment these lines in place of build: above +build: $(SOURCES) + @echo "Compiling readseq with NCBI toolkit support..."; + $(CC) -o readseq $(NLDFLAGS) $(NCFLAGS) readseq.c ureadseq.c ureadasn.c $(NLIBS) + +test: $(SOURCES) readseq + @echo "" + @echo "Test for general read/write of all chars:" + ./readseq -p alphabet.std -otest.alpha + -diff test.alpha alphabet.std + + @echo "" + @echo "Test for valid format conversions:" + ./readseq -v -p -f=ig nucleic.std -otest.ig + ./readseq -v -p -f=gb test.ig -otest.gb + ./readseq -v -p -f=nbrf test.gb -otest.nbrf + ./readseq -v -p -f=embl test.nbrf -otest.embl + ./readseq -v -p -f=gcg test.embl -otest.gcg + ./readseq -v -p -f=strider test.gcg -otest.strider + ./readseq -v -p -f=fitch test.strider -otest.fitch + ./readseq -v -p -f=fasta test.fitch -otest.fasta + ./readseq -v -p -f=pir test.fasta -otest.pir + ./readseq -v -p -f=ig test.pir -otest.ig-b + -diff test.ig test.ig-b + + @echo "" + @echo "Test for multiple-sequence format conversions:" + ./readseq -p -f=ig multi.std -otest.m-ig + ./readseq -p -f=gb test.m-ig -otest.m-gb + ./readseq -p -f=nbrf test.m-gb -otest.m-nbrf + ./readseq -p -f=embl test.m-nbrf -otest.m-embl + ./readseq -p -f=fasta test.m-embl -otest.m-fasta + ./readseq -p -f=pir test.m-fasta -otest.m-pir + ./readseq -p -f=msf test.m-pir -otest.m-msf + ./readseq -p -f=paup test.m-msf -otest.m-paup + ./readseq -p -f=ig test.m-paup -otest.m-ig-b + -diff test.m-ig test.m-ig-b +# +# if using NCBI, uncomment these lines + @echo "" + @echo "Test of NCBI ASN.1 conversions:" + ./readseq -p -f=asn test.m-ig -otest.m-asn + ./readseq -p -f=ig test.m-asn -otest.m-ig-c + -diff test.m-ig test.m-ig-c +# + @echo "" + @echo "Expect differences in the header lines due to" + @echo "different format headers. If any sequence lines" + @echo "differ, or if the checksums differ, there is a problem." + @echo "----------------------" + @echo "" + @echo "To clean up test files, command me:" + @echo " make clean" + + +clean: + rm -f *.o core test.* + +shar: + @echo "shell archiving files..." + -rm -f readseq*.shar + mkdir readseqd + cp $(SOURCES) readseqd + cp $(DOCS) readseqd + shar -v readseqd > readseq.shar + rm -rf readseqd + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Makefile new file mode 100755 index 00000000..3c674326 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Makefile @@ -0,0 +1,111 @@ +# +# Unix Makefile for readseq +# to use, command me: +# % make -- or -- +# % make CC=your-c-compiler-name +# + +# pick an ANSI C compiler (the default Sun CC is not ANSI) +#CC=gcc # Gnu C Compiler +CC=cc # SGI Irix +#CC=vcc # some DEC Ultrix + +CFLAGS= +#CFLAGS= -DSMALLCHECKSUM # if you prefer to use a GCG-standard 13 bit checksum +# instead of a full 32 bit checksum. This may enhance compatibility w/ GCG software + +SOURCES= readseq.c ureadseq.c ureadseq.h ureadasn.c +DOCS= Readme Readseq.help Formats Stdfiles Makefile Make.com add.gdemenu *.std + + +# NCBI toolkit support for ASN.1 reader + +# this is path to NCBI toolkit, you must set for your system: +NCBI= +#NCBI=/bio/mb/ncbi +# +OTHERLIBS=-lm +LIB1=-lncbi +LIB2=-lncbiobj +LIB3=-lncbicdr +LIB4=-lvibrant +INCPATH=$(NCBI)/include +LIBPATH=$(NCBI)/lib +NCFLAGS=$(CFLAGS) -DNCBI -I$(INCPATH) +NLDFLAGS=-I$(INCPATH) -L$(LIBPATH) +NLIBS=$(LIB1) $(LIB2) $(OTHERLIBS) + + +all: build test + +build: $(SOURCES) + @echo "Compiling readseq..." + $(CC) $(CFLAGS) -o readseq readseq.c ureadseq.c + +# if using NCBI, uncomment these lines in place of build: above +#build: $(SOURCES) +# @echo "Compiling readseq with NCBI toolkit support..."; +# $(CC) -o readseq $(NLDFLAGS) $(NCFLAGS) readseq.c ureadseq.c ureadasn.c $(NLIBS) + +test: $(SOURCES) readseq + @echo "" + @echo "Test for general read/write of all chars:" + ./readseq -p alphabet.std -otest.alpha + -diff test.alpha alphabet.std + + @echo "" + @echo "Test for valid format conversions:" + ./readseq -v -p -f=ig nucleic.std -otest.ig + ./readseq -v -p -f=gb test.ig -otest.gb + ./readseq -v -p -f=nbrf test.gb -otest.nbrf + ./readseq -v -p -f=embl test.nbrf -otest.embl + ./readseq -v -p -f=gcg test.embl -otest.gcg + ./readseq -v -p -f=strider test.gcg -otest.strider + ./readseq -v -p -f=fitch test.strider -otest.fitch + ./readseq -v -p -f=fasta test.fitch -otest.fasta + ./readseq -v -p -f=pir test.fasta -otest.pir + ./readseq -v -p -f=ig test.pir -otest.ig-b + -diff test.ig test.ig-b + + @echo "" + @echo "Test for multiple-sequence format conversions:" + ./readseq -p -f=ig multi.std -otest.m-ig + ./readseq -p -f=gb test.m-ig -otest.m-gb + ./readseq -p -f=nbrf test.m-gb -otest.m-nbrf + ./readseq -p -f=embl test.m-nbrf -otest.m-embl + ./readseq -p -f=fasta test.m-embl -otest.m-fasta + ./readseq -p -f=pir test.m-fasta -otest.m-pir + ./readseq -p -f=msf test.m-pir -otest.m-msf + ./readseq -p -f=paup test.m-msf -otest.m-paup + ./readseq -p -f=ig test.m-paup -otest.m-ig-b + -diff test.m-ig test.m-ig-b +# +# if using NCBI, uncomment these lines +# @echo "" +# @echo "Test of NCBI ASN.1 conversions:" +# ./readseq -p -f=asn test.m-ig -otest.m-asn +# ./readseq -p -f=ig test.m-asn -otest.m-ig-c +# -diff test.m-ig test.m-ig-c +# + @echo "" + @echo "Expect differences in the header lines due to" + @echo "different format headers. If any sequence lines" + @echo "differ, or if the checksums differ, there is a problem." + @echo "----------------------" + @echo "" + @echo "To clean up test files, command me:" + @echo " make clean" + + +clean: + rm -f *.o core test.* + +shar: + @echo "shell archiving files..." + -rm -f readseq*.shar + mkdir readseqd + cp $(SOURCES) readseqd + cp $(DOCS) readseqd + shar -v readseqd > readseq.shar + rm -rf readseqd + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readme b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readme new file mode 100755 index 00000000..6efd1f45 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readme @@ -0,0 +1,160 @@ + + * ReadSeq -- 1 Feb 93 + * + * Reads and writes nucleic/protein sequences in various + * formats. Data files may have multiple sequences. + * + * Copyright 1990 by d.g.gilbert + * biology dept., indiana university, bloomington, in 47405 + * e-mail: gilbertd@bio.indiana.edu + * + * This program may be freely copied and used by anyone. + * Developers are encourged to incorporate parts in their + * programs, rather than devise their own private sequence + * format. + * + * This should compile and run with any ANSI C compiler. + * Please advise me of any bugs, additions or corrections. + +Readseq has been updated. There have been a number of enhancements +and a few bug corrections since the previous general release in Nov 91 +(see below). If you are using earlier versions, I recommend you update to +this release. + +Readseq is particularly useful as it automatically detects many +sequence formats, and interconverts among them. +Formats added to this release include + + MSF multi sequence format used by GCG software + + PAUP's multiple sequence (NEXUS) format + + PIR/CODATA format used by PIR + + ASN.1 format used by NCBI + + Pretty print with various options for nice looking output. + +As well, Phylip format can now be used as input. Options to +reverse-compliment and to degap sequences have been added. A menu +addition for users of the GDE sequence editor is included. + +This program is available thru Internet gopher, as + + gopher ftp.bio.indiana.edu + browse into the IUBio-Software+Data/molbio/readseq/ folder + select the readseq.shar document + +Or thru anonymous FTP in this manner: + my_computer> ftp ftp.bio.indiana.edu (or IP address 129.79.224.25) + username: anonymous + password: my_username@my_computer + ftp> cd molbio/readseq + ftp> get readseq.shar + ftp> bye + +readseq.shar is a Unix shell archive of the readseq files. +This file can be editted by any text editor to reconstitute the +original files, for those who do not have a Unix system or an +Unshar program. Read the top of this .shar file for further +instructions. + +There are also pre-compiled executables for the following computers: +Silicon Graphics Iris, Sparc (Sun Sparcstation & clones), VMS-Vax, +Macintosh. Use binary ftp to transfer these, except Macintosh. The +Mac version is just the command-line program in a window, not very +handy. + +C source files: + readseq.c ureadseq.c ureadasn.c ureadseq.h +Document files: + Readme (this doc) + Readseq.help (longer than this doc) + Formats (description of sequence file formats) + add.gdemenu (GDE program users can add this to the .GDEmenu file) + Stdfiles -- test sequence files + Makefile -- Unix make file + Make.com -- VMS make file + *.std -- files for testing validity of readseq + + +Example usage: + readseq + -- for interactive use + readseq my.1st.seq my.2nd.seq -all -format=genbank -output=my.gb + -- convert all of two input files to one genbank format output file + readseq my.seq -all -form=pretty -nameleft=3 -numleft -numright -numtop -match + -- output to standard output a file in a pretty format + readseq my.seq -item=9,8,3,2 -degap -CASE -rev -f=msf -out=my.rev + -- select 4 items from input, degap, reverse, and uppercase them + cat *.seq | readseq -pipe -all -format=asn > bunch-of.asn + -- pipe a bunch of data thru readseq, converting all to asn + + +The brief usage of readseq is as follows. The "[]" denote +optional parts of the syntax: + + readseq -help +readSeq (27Dec92), multi-format molbio sequence reader. +usage: readseq [-options] in.seq > out.seq + options + -a[ll] select All sequences + -c[aselower] change to lower case + -C[ASEUPPER] change to UPPER CASE + -degap[=-] remove gap symbols + -i[tem=2,3,4] select Item number(s) from several + -l[ist] List sequences only + -o[utput=]out.seq redirect Output + -p[ipe] Pipe (command line, stdout) + -r[everse] change to Reverse-complement + -v[erbose] Verbose progress + -f[ormat=]# Format number for output, or + -f[ormat=]Name Format name for output: + 1. IG/Stanford 10. Olsen (in-only) + 2. GenBank/GB 11. Phylip3.2 + 3. NBRF 12. Phylip + 4. EMBL 13. Plain/Raw + 5. GCG 14. PIR/CODATA + 6. DNAStrider 15. MSF + 7. Fitch 16. ASN.1 + 8. Pearson/Fasta 17. PAUP + 9. Zuker 18. Pretty (out-only) + + Pretty format options: + -wid[th]=# sequence line width + -tab=# left indent + -col[space]=# column space within sequence line on output + -gap[count] count gap chars in sequence numbers + -nameleft, -nameright[=#] name on left/right side [=max width] + -nametop name at top/bottom + -numleft, -numright seq index on left/right side + -numtop, -numbot index on top/bottom + -match[=.] use match base for 2..n species + -inter[line=#] blank line(s) between sequence blocks + + + +Recent changes: + +4 May 92 ++ added 32 bit CRC checksum as alternative to GCG 6.5bit checksum +Aug 92 += fixed Olsen format input to handle files w/ more sequences, + not to mess up when more than one seq has same identifier, + and to convert number masks to symbols. += IG format fix to understand ^L +30 Dec 92 +* revised command-line & interactive interface. Suggested form is now + readseq infile -format=genbank -output=outfile -item=1,3,4 ... + but remains compatible with prior commandlines: + readseq infile -f2 -ooutfile -i3 ... ++ added GCG MSF multi sequence file format ++ added PIR/CODATA format ++ added NCBI ASN.1 sequence file format ++ added Pretty, multi sequence pretty output (only) ++ added PAUP multi seq format ++ added degap option ++ added Gary Williams (GWW, G.Williams@CRC.AC.UK) reverse-complement option. ++ added support for reading Phylip formats (interleave & sequential) +* string fixes, dropped need for compiler flags NOSTR, FIXTOUPPER, NEEDSTRCASECMP +* changed 32bit checksum to default, -DSMALLCHECKSUM for GCG version + +1Feb93 += reverted Genbank output format to fixed left margin + (change in 30 Dec release), so GDE and others relying on fixed margin + can read this. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readseq.help b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readseq.help new file mode 100755 index 00000000..08fdc080 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Readseq.help @@ -0,0 +1,229 @@ + + * ReadSeq.Help -- 30 Dec 92 + * + * Reads and writes nucleic/protein sequences in various + * formats. Data files may have multiple sequences. + * + * Copyright 1990 by d.g.gilbert + * biology dept., indiana university, bloomington, in 47405 + * e-mail: gilbertd@bio.indiana.edu + * + * This program may be freely copied and used by anyone. + * Developers are encourged to incorporate parts in their + * programs, rather than devise their own private sequence + * format. + * + * This should compile and run with any ANSI C compiler. + * Please advise me of any bugs, additions or corrections. + +Readseq is particularly useful as it automatically detects many +sequence formats, and interconverts among them. + +Formats which readseq currently understands: + + * IG/Stanford, used by Intelligenetics and others + * GenBank/GB, genbank flatfile format + * NBRF format + * EMBL, EMBL flatfile format + * GCG, single sequence format of GCG software + * DNAStrider, for common Mac program + * Fitch format, limited use + * Pearson/Fasta, a common format used by Fasta programs and others + * Zuker format, limited use. Input only. + * Olsen, format printed by Olsen VMS sequence editor. Input only. + * Phylip3.2, sequential format for Phylip programs + * Phylip, interleaved format for Phylip programs (v3.3, v3.4) + * Plain/Raw, sequence data only (no name, document, numbering) + + MSF multi sequence format used by GCG software + + PAUP's multiple sequence (NEXUS) format + + PIR/CODATA format used by PIR + + ASN.1 format used by NCBI + + Pretty print with various options for nice looking output. Output only. + +See the included "Formats" file for detail on file formats. + + +Example usage: + readseq + -- for interactive use + + readseq my.1st.seq my.2nd.seq -all -format=genbank -output=my.gb + -- convert all of two input files to one genbank format output file + + readseq my.seq -all -form=pretty -nameleft=3 -numleft -numright -numtop -match + -- output to standard output a file in a pretty format + + readseq my.seq -item=9,8,3,2 -degap -CASE -rev -f=msf -out=my.rev + -- select 4 items from input, degap, reverse, and uppercase them + + cat *.seq | readseq -pipe -all -format=asn > bunch-of.asn + -- pipe a bunch of data thru readseq, converting all to asn + + +The brief usage of readseq is as follows. The "[]" denote +optional parts of the syntax: + +readseq -help +readSeq (27Dec92), multi-format molbio sequence reader. +usage: readseq [-options] in.seq > out.seq + options + -a[ll] select All sequences + -c[aselower] change to lower case + -C[ASEUPPER] change to UPPER CASE + -degap[=-] remove gap symbols + -i[tem=2,3,4] select Item number(s) from several + -l[ist] List sequences only + -o[utput=]out.seq redirect Output + -p[ipe] Pipe (command line, stdout) + -r[everse] change to Reverse-complement + -v[erbose] Verbose progress + -f[ormat=]# Format number for output, or + -f[ormat=]Name Format name for output: + 1. IG/Stanford 10. Olsen (in-only) + 2. GenBank/GB 11. Phylip3.2 + 3. NBRF 12. Phylip + 4. EMBL 13. Plain/Raw + 5. GCG 14. PIR/CODATA + 6. DNAStrider 15. MSF + 7. Fitch 16. ASN.1 + 8. Pearson/Fasta 17. PAUP + 9. Zuker 18. Pretty (out-only) + + Pretty format options: + -wid[th]=# sequence line width + -tab=# left indent + -col[space]=# column space within sequence line on output + -gap[count] count gap chars in sequence numbers + -nameleft, -nameright[=#] name on left/right side [=max width] + -nametop name at top/bottom + -numleft, -numright seq index on left/right side + -numtop, -numbot index on top/bottom + -match[=.] use match base for 2..n species + -inter[line=#] blank line(s) between sequence blocks + + +Notes: + +In use, readseq will respond to command line arguments, or to +interactive use. Command line arguments cannot be combined +but must each follow a switch character (-). In this release, +the command line options are now words, with an equals (=) +to separate parameter(s) fromt he command. You cannot put a +space between a command and its parameter, as is usual for +Unix programs (this is to preserve compatibility with VMS). +The command line syntax of the earlier versions is still +supported. + +See the file Formats for details of the sequence formats which +are supported by readseq. The auto-detection feature of +readseq which distinguishes these formats looks for some of the +unique keywords and symbols that are found in each format. It +is not infallible at this, though it attempts to exclude unknown +formats. In general, if you feed to readseq a sequence file that +you know is one of these common formats, you are okay. If you feed +it data that might be oddball formats, or non-sequence data, +you might well get garbage results. Also, different developers +are always thinking up minor twists on these common formats +(like PAUP requiring a blank line between blocks of Phylip format, +or IG adding form feeds between sequences), which may cause hassles. + +In general, output supports only minimal subsets of each format +needed for sequence data exchanges. Features, descriptions +and other format-unique information is discarded. + +The pretty format requires additional options to generate a +nice output. Try the various pretty options to see what you like. +Pretty format is OUPUT only, readseq cannot read a Pretty format +file. + +Readseq is NOT optimized for LARGE files. It generally makes several +reads thru each input file (one per sequence output at present, future +version may optimize this). It should handle input and output files +and sequences of any size, but will slow down quite a bit for very large +(multi megabyte) sized files. It is NOT recommended for converting +databanks or large subsets there-of. It is primarily directed at the +small files that researchers use to maintain their personal data, which +they frequently need to interconvert for the various analysis programs +which so frequently require a special format. + +Users of Olsen multi sequence editor (VMS). The Olsen format +here is produced with the print command: + print/out=some.file +Use Genbank output from readseq to produce a format that this +editor can read, and use the command + load/genbank some.file +Dan Davison has a VMS program that will convert to/from the +Olsen native binary data format. E-mail davison@uh.edu + +Warning: Phylip format input is now supported (30Dec92), however the +auto-detection of Phylip format is very probabilistic and messy, +especially distinguishing sequential from interleaved versions. It +is not recommended that one use readseq to convert files from Phylip +format to others unless essential. + + +This program is available thru Internet gopher, as + + gopher ftp.bio.indiana.edu + browse into the IUBio-Software+Data/molbio/readseq/ folder + select the readseq.shar document + +Or thru anonymous FTP in this manner: + my_computer> ftp ftp.bio.indiana.edu (or IP address 129.79.224.25) + username: anonymous + password: my_username@my_computer + ftp> cd molbio/readseq + ftp> get readseq.shar + ftp> bye + +readseq.shar is a Unix shell archive of the readseq files. +This file can be editted by any text editor to reconstitute the +original files, for those who do not have a Unix system or an +Unshar program. Read the top of this .shar file for further +instructions. + +There are also pre-compiled executables for the following computers: +Silicon Graphics Iris, Sparc (Sun Sparcstation & clones), VMS-Vax, +Macintosh. Use binary ftp to transfer these, except Macintosh. The +Mac version is just the command-line program in a window, not very +handy. + +C source files: + readseq.c ureadseq.c ureadasn.c ureadseq.h + +Document files: + Readme (this doc) + Formats (description of sequence file formats) + add.gdemenu (GDE program users can add this to the .GDEmenu file) + Stdfiles -- test sequence files + Makefile -- Unix make file + Make.com -- VMS make file + *.std -- files for testing validity of readseq + + +Recent changes (see also readseq.c for all history of changes): + +4 May 92 ++ added 32 bit CRC checksum as alternative to GCG 6.5bit checksum +Aug 92 += fixed Olsen format input to handle files w/ more sequences, + not to mess up when more than one seq has same identifier, + and to convert number masks to symbols. += IG format fix to understand ^L +30 Dec 92 +* revised command-line & interactive interface. Suggested form is now + readseq infile -format=genbank -output=outfile -item=1,3,4 ... + but remains compatible with prior commandlines: + readseq infile -f2 -ooutfile -i3 ... ++ added GCG MSF multi sequence file format ++ added PIR/CODATA format ++ added NCBI ASN.1 sequence file format ++ added Pretty, multi sequence pretty output (only) ++ added PAUP multi seq format ++ added degap option ++ added Gary Williams (GWW, G.Williams@CRC.AC.UK) reverse-complement option. ++ added support for reading Phylip formats (interleave & sequential) +* string fixes, dropped need for compiler flags NOSTR, FIXTOUPPER, NEEDSTRCASECMP +* changed 32bit checksum to default, -DSMALLCHECKSUM for GCG version + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Stdfiles b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Stdfiles new file mode 100755 index 00000000..f72ad1e3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/Stdfiles @@ -0,0 +1,134 @@ +/* Stdfiles + generate standard files to test readseq +*/ + +C +#include +/* no sequence formats use chars > #126, ignore these */ +main(void) +{ + int c; + puts("> alphabet['!'..'~']"); + for (c = '!'; c <= '~'; c++) putc(c,stdout); + putc('\n', stdout); +} + +link -w -t MPST -c 'MPS ' c.o ¶ + "{Libraries}"Interface.o "{Libraries}"ToolLibs.o ¶ + "{Libraries}"Runtime.o "{CLibraries}"StdClib.o +link.out > alphabet.orig + + +C +#include +main(void) +{ +/* note: symbols "*" and "/" removed as terminators for various formats */ +const char *aminos = "ABCDEFGHIKLMNPQRSTVWXYZ"; +const char *primenuc = "ACGTU"; +const char *allsymbols = "_.-?<>{}[]()!@#$%^&=+;:'|`~\"\\"; + + char *c, all[256]; + int count; + + strcpy(all, aminos); + strcat(all, primenuc); + strcat(all, allsymbols); + puts("> nucleic/amino test"); + for (count=0; count<4; count++) { + for (c = all; *c!=0; c++) putc(*c, stdout); + putc('\n', stdout); + } +} + +link -w -t MPST -c 'MPS ' c.o ¶ + "{Libraries}"Interface.o "{Libraries}"ToolLibs.o ¶ + "{Libraries}"Runtime.o "{CLibraries}"StdClib.o +link.out > nucleic.std + +#-------------------------- + +#standards (ship w/ readseq) +#note: not all alphabet.orig chars are expected to be passed by +# readseq. Numbers are dropped. +readseq -p alphabet.orig > alphabet.std +readseq -p -C alphabet.std > upper.std + +cat alphabet.orig + > alphabet['!'..'~'] + !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~ + +cat alphabet.std + >alphabet['!'..'~'], 83 bases, 9429 checksum. + !"#$%&'()*+-./:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\] + ^_`abcdefghijklmnopqrstuvwxyz{|}~ + +cat upper.std + >alphabet['!'..'~'], 83 bases, 9429 checksum. + !"#$%&'()*+-./:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\] + ^_`ABCDEFGHIJKLMNOPQRSTUVWXYZ{|}~ + +cat nucleic.std + > nucleic/amino test + ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ + ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ + ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ + ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ + +readseq -p nucleic.std + >nucleic/amino test, 228 bases, 5952 checksum. + ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+; + :'|`~"\ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@# + $%^&=+;:'|`~"\ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{} + []()!@#$%^&=+;:'|`~"\ABCDEFGHIKLMNPQRSTVWXYZACGTU_ + .-?<>{}[]()!@#$%^&=+;:'|`~"\ + + +#---------------------------------- + +#test for general read/write of all chars: +readseq -p alphabet.std -otest.alpha +diff test.alpha alphabet.std + +#test for valid toupper, general read/write: +readseq -p -C alphabet.std -otest.upper +diff test.upper upper.std +#for vms, use "-C" to preserve case +# readseq -p "-C" alphabet.std -otest.upper + +#test for multiple sequence file conversions +# leave out gcg, raw; +# test of long seq conversion ? +# test of mail-header seq conversion ? + +#test for valid format conversions +readseq -v -p -f1 nucleic.std -otest.f1 +readseq -v -p -f2 test.f1 -otest.f2 +readseq -v -p -f3 test.f2 -otest.f3 +readseq -v -p -f4 test.f3 -otest.f4 +readseq -v -p -f5 test.f4 -otest.f5 +readseq -v -p -f6 test.f5 -otest.f6 +readseq -v -p -f7 test.f6 -otest.f7 +readseq -v -p -f8 test.f7 -otest.f8 +readseq -v -p -f1 test.f8 -otest.f1b +diff test.f1 test.f1b +compare test.f1 test.f1b + +readseq -v -p -f13 test.f8 -otest.f13 # raw, drops name +readseq -v -p -f9 test.f8 -otest.f9 # zuker, little used +#readseq -v -p -f10 test.f9 -otest.f10 # olsen, input only (output=raw) +readseq -v -p -f11 test.f8 -otest.f11 # phylip 3.2, output only +readseq -v -p -f12 test.f8 -otest.f12 # phylip 3.3, output only +readseq -v -p -f14 test.f8 -otest.f14 # phylip 3.4, output only + + +#clean up +rm test.Å + + +#----------------------------- +# some general tests + +readseq -h + +readseq diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/add.gdemenu b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/add.gdemenu new file mode 100755 index 00000000..12818f65 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/add.gdemenu @@ -0,0 +1,123 @@ +# +# dgg added new readseq formats, 29 dec 92 +# + +item:Export Foreign Format +itemmethod:readseq in1 -pipe -all -form=$FORMAT > $OUTPUTFILE +itemhelp:readseq.help + +arg:FORMAT +argtype:choice_menu +argchoice:GenBank:genbank +argchoice:IG/Stanford:ig +argchoice:NBRF:nbrf +argchoice:EMBL:embl +argchoice:GCG:gcg +argchoice:DNA Strider:strider +argchoice:Fitch:fitch +argchoice:Pearson/Fasta:pearson +argchoice:Zuker:zuker +argchoice:Olsen:olsen +argchoice:Phylip:phylip +#argchoice:Phylip v3.2:phylip3.2 +argchoice:Plain text:raw +argchoice:ASN.1:asn +argchoice:PIR:pir +argchoice:MSF:msf +argchoice:PAUP:paup +argchoice:Pretty:pretty -nametop -nameleft=3 -numright -nameright -numtop + +arg:OUTPUTFILE +argtype:text +arglabel:Save as? + +in:in1 +informat:genbank + + +# +#dgg addition for new readseq, 24 dec 92 +# + +item:Pretty Print +itemmethod:readseq in1 -p -a -f=pretty $NAMELEFT $NAMERIGHT $NUMTOP $NUMBOT $NUMLEFT $NUMRIGHT -col=$COLS -width=$WIDTH $MATCH $GAPC > in1.pretty; (textedit in1.pretty; /bin/rm -f in1 in1.pretty)& +itemhelp:readseq.help + +#nametop is bad !? + +in:in1 +informat:genbank + +arg:NAMETOP +argtype:chooser +arglabel:Names at top ? +argchoice:No: +argchoice:Yes:-nametop + +arg:NAMELEFT +argtype:chooser +arglabel:Names at left ? +argchoice:No: +argchoice:Yes:-nameleft + +arg:NAMERIGHT +argtype:chooser +arglabel:Names at right? +argchoice:Yes:-nameright +argchoice:No: + +arg:NUMTOP +argtype:chooser +arglabel:Numbers at top ? +argchoice:Yes:-numtop +argchoice:No: + +arg:NUMBOT +argtype:chooser +arglabel:Numbers at tail ? +argchoice:No: +argchoice:Yes:-numbot + +arg:NUMLEFT +argtype:chooser +arglabel:Numbers at left ? +argchoice:Yes:-numleft +argchoice:No: + +arg:NUMRIGHT +argtype:chooser +arglabel:Numbers at right? +argchoice:Yes:-numright +argchoice:No: + +arg:MATCH +argtype:chooser +arglabel:Use match '.' for 2..n species? +argchoice:No: +argchoice:Yes:-match + +arg:GAPC +argtype:chooser +arglabel:Count gap symbols? +argchoice:No: +argchoice:Yes:-gap + +arg:WIDTH +argtype:slider +arglabel:Sequence width? +argmin:10 +argmax:200 +argvalue:50 + +arg:COLS +argtype:slider +arglabel:Column spacers? +argmin:0 +argmax:50 +argvalue:10 + + +### pretty print insert end +# + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/alphabet.std b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/alphabet.std new file mode 100755 index 00000000..e6dc9533 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/alphabet.std @@ -0,0 +1,3 @@ +>alphabet['!'..'~'], 83 bases, 9429 checksum. +!"#$%&'()*+-./:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\] +^_`abcdefghijklmnopqrstuvwxyz{|}~ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.c new file mode 100755 index 00000000..5a049ade --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.c @@ -0,0 +1,302 @@ +/* + macinit.c + -- Macintosh initializations, then call real main + +Note: compile this segment as Main for generic 68000 processor, so it won't + fail on generic mac + +*/ + +#pragma segment Main + +#include +#include +#include +#include +#include + +#include +#include +#include +#include +#include +#include +#include +#include +#include +//#include +//#include + + +Boolean StopKey() +{ +EventRecord ev; + + if (EventAvail( keyDownMask+autoKeyMask, &ev)) { + if ( (ev.modifiers & cmdKey) + && ((char)(ev.message & charCodeMask) == '.') ) { + SysBeep(1); + (void) GetNextEvent( keyDownMask+autoKeyMask, &ev); + return true; + } + } + return false; +} + +Boolean cmdKeyIsDown() +{ KeyMap kmap; + GetKeys(&kmap); + return BitTst(kmap, (sizeof(KeyMap)*8) - 55); +} + +Boolean shiftKeyIsDown() +{ KeyMap kmap; + GetKeys(&kmap); + return BitTst(kmap, (sizeof(KeyMap)*8) - 56); +} + +Boolean capsLockIsDown() +{ KeyMap kmap; + GetKeys(&kmap); + return BitTst(kmap, (sizeof(KeyMap)*8) - 57); +} + +Boolean optionKeyIsDown() +{ KeyMap kmap; + GetKeys(&kmap); + return BitTst(kmap, (sizeof(KeyMap)*8) - 58); +} + +Boolean MouseButton() +{ + return Button(); +} + +Boolean Keypress() +{ EventRecord ev; + return EventAvail( keyDownMask+keyUpMask+autoKeyMask, &ev); +} + + + +char *StdGetFile( + char* prompt, + OSType fileTypes[], + int nFileTypes) +{ + Point wher; /*where to display dialog*/ + SFReply reply; /*reply record*/ + short len; + static char filename[80] = "\0"; + + wher.h = 80; + wher.v = 90; + if (optionKeyIsDown()) nFileTypes=0; + + SFGetFile(wher, prompt, nil, nFileTypes, fileTypes, nil, &reply); + + if (reply.good) { + len = SetVol(nil, reply.vRefNum); + len = reply.fName[0]; + strncpy(filename, (char *)(&reply.fName[1]), len); + filename[len]= '\0'; + return filename; + } + else + return NULL; +} + + +int readCmdOptions(FILE *cl, char *progname, char ***argv) +/* command line reader for Mac/MPW -- dgg */ +{ +#define MAXS 255 +#define addarg(sptr) if (strlen(sptr)>0) { \ + targv = (char **) realloc( targv, (argc+1) * sizeof(char *)); \ + targv[argc] = (char *) malloc(1+strlen(sptr) * sizeof(char)); \ + strcpy( targv[argc], sptr); \ + argc++; } + + char *pword, st[MAXS]; + int argc = 0; + char **targv; + + targv = (char **) malloc(1); + if (progname==NULL) progname = "program"; + addarg( progname); + fgets( st, MAXS, cl); + if (!feof(cl) && st!=NULL && *st!=0) { + pword = strtok( st, "\ \n"); + while (pword!=NULL) { + addarg( pword); + pword = strtok( NULL, "\ \n"); + } + } + + *argv = targv; + return argc; +} + +int ccommand(char ***argv) +{ + int argc; + char **targv; + + argc = readCmdOptions(stdin, *argv[0], &targv); + *argv = targv; + return argc; +} + + + + +extern _DataInit(); + +//#define VERSION curSysEnvVers +#define nocolorID 130 +#define no68020 133 +#define no68881 132 +#define no256 134 +#define nosys6 135 + +void MacInit() +{ +SysEnvRec theWorld; +OSErr OSys; +DialogPtr crashDia; +long tick; + + UnloadSeg(_DataInit); + + InitGraf((Ptr)&qd.thePort); + //InitFonts(); + InitWindows(); + //InitMenus(); + //TEInit(); + InitDialogs(nil); + InitCursor(); + +/*______________________________________________________*/ +/* If not right Machine then stop */ +/*______________________________________________________*/ + OSys = SysEnvirons( curSysEnvVers,&theWorld); + + /*if(!theWorld.hasColorQD) { + crashDia = GetNewDialog (nocolorID, nil, (WindowPtr) -1); + DrawDialog (crashDia); + Delay (300, &tick); + ExitToShell(); + }*/ + /*if(theWorld.processor < env68020) { + crashDia = GetNewDialog (no68020, nil, (WindowPtr) -1); + DrawDialog (crashDia); + Delay (300, &tick); + ExitToShell(); + }*/ + /*if(!theWorld.hasFPU) { + crashDia = GetNewDialog (no68881, nil, (WindowPtr) -1); + DrawDialog (crashDia); + Delay (300, &tick); + ExitToShell(); + } + if(theWorld.systemVersion < 0x0600) { + crashDia = GetNewDialog (nosys6, nil, (WindowPtr) -1); + DrawDialog (crashDia); + Delay (300, &tick); + ExitToShell(); + }*/ + +#ifdef UnDeFineD +/*______________________________________________________*/ +/* Set Rects */ +/*______________________________________________________*/ + screenRect = qd.screenBits.bounds; + offLeft = 0; + offTop = 0; + offRight = screenRect.right; + offBottom = screenRect.bottom; + SetRect(&BaseRect, 40, 60, 472, 282); + tempRgn = GetGrayRgn(); + HLock ((Handle) tempRgn); + TotalRect = (**tempRgn).rgnBBox; + SetRect(&minRect, 80, 80, (**tempRgn).rgnBBox.right - 40, + (**tempRgn).rgnBBox.bottom - 40); + HUnlock ((Handle) tempRgn); + +/*______________________________________________________*/ +/* Open Window & set Palette & Picture */ +/*______________________________________________________*/ + theGDevice = GetMainDevice(); + HLock ((Handle) theGDevice); + mycolors = (**(**theGDevice).gdPMap).pmTable; + numcolor = (**(**theGDevice).gdPMap).pixelSize; + HUnlock((Handle) theGDevice); + switch (numcolor) { + case 1: + numcolor = 2; + break; + case 2: + numcolor = 4; + break; + case 4: + numcolor = 16; + break; + case 8: + numcolor = 256; + break; + } + + myWindow = NewCWindow(nil, &BaseRect, "", true, zoomDocProc, + (WindowPtr) -1, true, 150); + SetPort((WindowPtr) myWindow); + DrawGrowIcon (myWindow); + + srcPalette = NewPalette (numcolor, mycolors, pmCourteous, 0); + SetPalette ((WindowPtr) myWindow, srcPalette, true); + +/*______________________________________________________*/ +/* Set menus */ +/*______________________________________________________*/ + mymenu0 = GetMenu(appleID); + AddResMenu(mymenu0, 'DRVR'); + InsertMenu(mymenu0,0); + mymenu1 = newmenu(129,"File"); + appendmenu(mymenu1,"Start;Quit"); + InsertMenu(mymenu1,0); + mymenu2 = newmenu(130,"Edit"); + InsertMenu(mymenu2,0); + DrawMenuBar(); + +/*______________________________________________________*/ +/* Init variables */ +/*______________________________________________________*/ + DoneFlag = false; + yieldTime = 0; + return; +#endif + +} + + + + +main(int argc, char *argv[]) +{ + Boolean loop = true; + char **myargv; + int myargc; + + /* MacInit(); -- SIOW library handles this */ + do { + fprintf(stderr,"\nEnter command line for %s [cmd-Q to quit]\n", argv[0]); + fprintf(stderr,"-> %s ",argv[0]); + myargv = argv; + myargc = ccommand(&myargv); + + siow_main(myargc, myargv); + fflush(stdout); + + } while (true); + exit(0); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.r b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.r new file mode 100755 index 00000000..fb8e74b1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/macinit.r @@ -0,0 +1,412 @@ +/*------------------------------------------------------------------------------ +# +# +# MultiFinder-Aware Simple Input/Output Window resource +# +# for ReadSeq +# +------------------------------------------------------------------------------*/ + +#include "systypes.r" +#include "types.r" + + +resource 'MENU' (20000, preload) { + 20000, + textMenuProc, + 0x7FFFFFFD, + enabled, + apple, + { /* array: 2 elements */ + /* [1] */ + "About ReadSeqÉ", noIcon, noKey, noMark, plain, + /* [2] */ + "-", noIcon, noKey, noMark, plain + } +}; + +resource 'MENU' (20001, preload) { + 20001, + textMenuProc, + 0x0, + enabled, + "File", + { /* array: 11 elements */ + /* [1] */ + "New", noIcon, "N", noMark, plain, + /* [2] */ + "Open", noIcon, "O", noMark, plain, + /* [3] */ + "-", noIcon, noKey, noMark, plain, + /* [4] */ + "Close", noIcon, "W", noMark, plain, + /* [5] */ + "Save", noIcon, "S", noMark, plain, + /* [6] */ + "Save AsÉ", noIcon, noKey, noMark, plain, + /* [7] */ + "-", noIcon, noKey, noMark, plain, + /* [8] */ + "Page SetupÉ", noIcon, noKey, noMark, plain, + /* [9] */ + "PrintÉ", noIcon, noKey, noMark, plain, + /* [10] */ + "-", noIcon, noKey, noMark, plain, + /* [11] */ + "Quit", noIcon, "Q", noMark, plain + } +}; + +resource 'MENU' (20002, preload) { + 20002, + textMenuProc, + 0x0, + enabled, + "Edit", + { /* array: 6 elements */ + /* [1] */ + "Undo", noIcon, "Z", noMark, plain, + /* [2] */ + "-", noIcon, noKey, noMark, plain, + /* [3] */ + "Cut", noIcon, "X", noMark, plain, + /* [4] */ + "Copy", noIcon, "C", noMark, plain, + /* [5] */ + "Paste", noIcon, "V", noMark, plain, + /* [6] */ + "Clear", noIcon, noKey, noMark, plain + } +}; + +resource 'MENU' (20003, preload) { + 20003, + textMenuProc, + allEnabled, + enabled, + "Font", + { /* array: 0 elements */ + } +}; + +resource 'ALRT' (20000, purgeable) { + {98, 108, 314, 405}, + 20000, + { /* array: 4 elements */ + /* [1] */ + OK, visible, silent, + /* [2] */ + OK, visible, silent, + /* [3] */ + OK, visible, silent, + /* [4] */ + OK, visible, silent + } +}; + +resource 'ALRT' (20001, purgeable) { + {40, 20, 150, 260}, + 20001, + { /* array: 4 elements */ + /* [1] */ + OK, visible, silent, + /* [2] */ + OK, visible, silent, + /* [3] */ + OK, visible, silent, + /* [4] */ + OK, visible, silent + } +}; + +resource 'ALRT' (20002, preload) { + {72, 64, 212, 372}, + 20002, + { /* array: 4 elements */ + /* [1] */ + OK, visible, silent, + /* [2] */ + OK, visible, silent, + /* [3] */ + OK, visible, silent, + /* [4] */ + OK, visible, silent + } +}; + +resource 'DITL' (20000, purgeable) { + { /* array DITLarray: 8 elements */ + /* [1] */ + {191, 98, 211, 178}, + Button { + enabled, + "OK" + }, + /* [2] */ + {110, 24, 130, 256}, + StaticText { + disabled, + " Copyright © 1990 by d.g.gilbert\n" + }, + /* [3] */ + {6, 93, 24, 281}, + StaticText { + disabled, + "A tool for molecular biology." + }, + /* [4] */ + {31, 25, 86, 281}, + StaticText { + disabled, + "Reads and writes nucleic or protein sequ" + "ences in various formats. Data files may" + " have multiple sequences." + }, + /* [5] */ + {6, 17, 22, 92}, + StaticText { + disabled, + "ReadSeq" + }, + /* [6] */ + {150, 28, 186, 262}, + StaticText { + disabled, + "land mail: biology dept., indiana univer" + "sity, bloomington, in 47405\n" + }, + /* [7] */ + {129, 25, 153, 258}, + StaticText { + disabled, + " e-mail: gilbertd@bio.indiana.edu\n" + }, + /* [8] */ + {86, 12, 107, 281}, + StaticText { + disabled, + "This program may be freely distributed." + } + } +}; + +resource 'DITL' (20001, purgeable) { + { /* array DITLarray: 3 elements */ + /* [1] */ + {80, 150, 100, 230}, + Button { + enabled, + "OK" + }, + /* [2] */ + {10, 60, 60, 230}, + StaticText { + disabled, + "Error. ^0." + }, + /* [3] */ + {8, 8, 40, 40}, + Icon { + disabled, + 2 + } + } +}; + +resource 'DITL' (20002, preload) { + { /* array DITLarray: 4 elements */ + /* [1] */ + {58, 25, 76, 99}, + Button { + enabled, + "Yes" + }, + /* [2] */ + {86, 25, 104, 99}, + Button { + enabled, + "No" + }, + /* [3] */ + {12, 20, 45, 277}, + StaticText { + disabled, + "Save changes before closing?" + }, + /* [4] */ + {86, 195, 104, 269}, + Button { + enabled, + "Cancel" + } + } +}; + +resource 'CNTL' (20000, purgeable, preload) { + {-1, 465, 272, 481}, + 0, + invisible, + 0, + 0, + scrollBarProc, + 0, + "" +}; + +resource 'CNTL' (20001, purgeable, preload) { + {271, -1, 287, 466}, + 0, + invisible, + 0, + 0, + scrollBarProc, + 0, + "" +}; + +data 'pzza' (128, purgeable) { + $"4D50 5320" /* MPS */ +}; + +resource 'MBAR' (20000, preload) { + { /* array MenuArray: 4 elements */ + /* [1] */ + 20000, + /* [2] */ + 20001, + /* [3] */ + 20002, + /* [4] */ + 20003 + } +}; + +resource 'WIND' (20000, purgeable, preload) { + {0, 0, 286, 480}, + zoomDocProc, + invisible, + noGoAway, + 0x0, + "untitled" +}; + +resource 'STR#' (20000, purgeable) { + { /* array StringArray: 11 elements */ + /* [1] */ + "You must run on 512Ke or later", + /* [2] */ + "Application Memory Size is too small", + /* [3] */ + "Not enough memory to run SIOW", + /* [4] */ + "Not enough memory to do Cut", + /* [5] */ + "Cannot do Cut", + /* [6] */ + "Cannot do Copy", + /* [7] */ + "Cannot exceed 32,000 characters with Pas" + "te", + /* [8] */ + "Not enough memory to do Paste", + /* [9] */ + "Cannot create window", + /* [10] */ + "Cannot exceed 32,000 characters", + /* [11] */ + "Cannot do PasteFont not found" + } +}; + +resource 'SIZE' (-1) { + reserved, + acceptSuspendResumeEvents, + reserved, + canBackground, + multiFinderAware, + backgroundAndForeground, + dontGetFrontClicks, + ignoreChildDiedEvents, + not32BitCompatible, + notHighLevelEventAware, + onlyLocalHLEvents, + notStationeryAware, + dontUseTextEditServices, + reserved, + reserved, + reserved, + 124928, + 38912 +}; + +resource 'SIZE' (0) { + reserved, + acceptSuspendResumeEvents, + reserved, + canBackground, + multiFinderAware, + backgroundAndForeground, + dontGetFrontClicks, + ignoreChildDiedEvents, + not32BitCompatible, + notHighLevelEventAware, + onlyLocalHLEvents, + notStationeryAware, + dontUseTextEditServices, + reserved, + reserved, + reserved, + 256000, + 38912 +}; + +data 'siow' (0) { + $"0F52 6561 6453 6571 2069 6E20 5349 4F57" /* .ReadSeq in SIOW */ +}; + +resource 'BNDL' (128) { + 'siow', + 0, + { /* array TypeArray: 2 elements */ + /* [1] */ + 'ICN#', + { /* array IDArray: 1 elements */ + /* [1] */ + 0, 128 + }, + /* [2] */ + 'FREF', + { /* array IDArray: 1 elements */ + /* [1] */ + 0, 128 + } + } +}; + +resource 'FREF' (128) { + 'APPL', + 0, + "" +}; + +resource 'ICN#' (128) { + { /* array: 2 elements */ + /* [1] */ + $"0000 0000 0000 0000 0010 4100 0010 2200" + $"0020 2200 0020 2100 0020 4100 0010 4200" + $"0010 4200 0010 2200 0020 2100 0020 0100" + $"00FF FF00 03FF FFE0 0791 03F0 0ED1 0E7C" + $"1C31 321C 380D C10E 3FFF FFFE 3003 C106" + $"380D 300E 1E31 0E3C 1FC1 01F8 07FF FFE0" + $"00FF FE", + /* [2] */ + $"0000 0000 0000 0000 0010 4100 0010 2200" + $"0020 2200 0020 2100 0020 4100 0010 4200" + $"0010 4200 0010 2200 0020 2100 0020 0100" + $"00FF FF00 03FF FFE0 07FF FFF0 0FFF FFFC" + $"1FFF FFFC 3FFF FFFE 3FFF FFFE 3FFF FFFE" + $"3FFF FFFE 1FFF FFFC 1FFF FFF8 07FF FFE0" + $"00FF FE" + } +}; + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/multi.std b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/multi.std new file mode 100755 index 00000000..2fb48be7 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/multi.std @@ -0,0 +1,25 @@ +>acarr58sst , 183 bases, 6EF8F222 checksum. +a-------actcctaacaacGgAtatCTtGgtT-CtcgcgagGatGAaGa +acGcAGcg--AaatGcGatacgtagtgtgaatcgc-agggatcagtgaat +catcgaatctttgaacgcaagttgcgctctcgtg--gtttaaccccccgg +gagc-acgttcgcttgagtgcc--gctt----- +>amgrrbst , 183 bases, 250C5F09 checksum. +----cgt--ccccgaacggcGgAtcaCTtGgcT-CgtggatcGatGAaGa +ccGcAGc--tAtctGcGcgtcgtcgtgtaatccgc-aggttatac--gaa +catcgaccagtcgaacgcacattgcggcctcggt--gacccgcgggcccc +gggccacgcctgtctgagggtc--gt------a +>bmorrbst , 183 bases, AF379101 checksum. +aaatgattaccctggacggtGgAtcaCTtGgcT-CgcgggtcGatGAaGa +acGcAGt--tAactGcGcgtcatagtgtgaactgc-aggacacatttgaa +catcgacatttcgaacgcacattgcggtc-cgtg--gagacaca--tcca +ggaccactcctgtctgagggcc--ggct----- +>crerrbst , 183 bases, AD1ECB91 checksum. +a-------actctcaacaacGgAtatCTtGgcT-CtcggatcGatGAaGg +acGcAGcg--AaatGcGatacgtagtgtgaactgc-agaaatacgtgaac +tatcgaatccctgaacgtatactgcgccc--gag--gcc---ccggt--a +gagc-atgtctgccttagtgct--gggt----t +>ddirr58sst , 183 bases, 783AEF3F checksum. +t-----taagcataaacggtGaAtacCTcGacTcC-caaattGatGAaGa +ccGtAGca--AactGcGataattcacttgaattgc-agcctactg-ggat +agttgaaatgttgaacgcacatgatgacatcggt---cctttcggattag +gtgttatacttgggtgagagt--------ggtc diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/nucleic.std b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/nucleic.std new file mode 100755 index 00000000..729b5b03 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/nucleic.std @@ -0,0 +1,5 @@ +> nucleic/amino test +ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ +ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ +ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ +ABCDEFGHIKLMNPQRSTVWXYZACGTU_.-?<>{}[]()!@#$%^&=+;:'|`~"\ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/readseq b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/readseq new file mode 100755 index 0000000000000000000000000000000000000000..4b3f498e792902ea5edb46dbde496cf6ca1fab4d GIT binary patch literal 50619 zcmd443w%^X(l^{mCNPA+L`1~v9uPDr30D<}!EhNa3ULIoB8VX*lT09)gk(l85*STp zO&Fu>DvGk4F`oa-E#Mc10|Mq8B8In3=q&78vT~&bO z(aVVJ;GYe+51gYze0RWS!JPru502zUzw_Wu=a3NRE8pr7u3l@ilYFVn0T4nP;3D`0 zlRnz(Z1z%>{y6-;fQde(XTzlerg8`-nT`UyLBR*%PXU|{!BIN#IUDfTDxKQL19-72 z?_Ph(LAiXc(Cly={KNWC; 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/readseq.c @@ -0,0 +1,1143 @@ +/* File: readseq.c + * main() program for ureadseq.c, ureadseq.h + * + * Reads and writes nucleic/protein sequence in various + * formats. Data files may have multiple sequences. + * + * Copyright 1990 by d.g.gilbert + * biology dept., indiana university, bloomington, in 47405 + * e-mail: gilbertd@bio.indiana.edu + * + * This program may be freely copied and used by anyone. + * Developers are encourged to incorporate parts in their + * programs, rather than devise their own private sequence + * format. + * + * This should compile and run with any ANSI C compiler. + * Please advise me of any bugs, additions or corrections. + * + */ + +const char *title + = "readSeq (1Feb93), multi-format molbio sequence reader.\n"; + + /* History + 27 Feb 90. 1st release to public. + 4 Mar 90. + Gary Olsen format + + case change + * minor corrections to NBRF,EMBL,others + * output 1 file per sequence for gcg, unknown + * define -DNOSTR for c-libraries w/o strstr + - readseq.p, pascal version, becomes out-of-date + 24 May 90. + Phylip 3.2 output format (no input) + 20 Jul 90. + Phylip 3.3 output (no input yet) + + interactive output re-direction + + verbose progress info + * interactive help output + * dropped line no.s on NBRF output + * patched in HyperGCG XCMD corrections, + - except for seq. documentation handling + * dropped the IG special nuc codes, as IG has + adopted the standard IUB codes (now if only + everyone would adopt a standard format !) + 11 Oct 90. * corrected bug in reading/writing of EMBL format + + 17 Oct 91. * corrected bug in reading Olsen format + (serious-deletion) + 10 Nov 91. * corrected bug in reading some GCG format files + (serious-last line duplicated) + + add format name parsing (-fgb, -ffasta, ...) + + Phylip v3.4 output format (== v3.2, sequential) + + add checksum output to all forms that have document + + skip mail headers in seq file + + add pipe for standard input == seq file (with -p) + * fold in parts of MacApp Seq object + * strengthen format detection + * clarify program structure + * remove fixed sequence size limit (now dynamic, sizeof memory) + * check and fold in accumulated bug reports: + * Now ANSI-C fopen(..,"w") & check open failure + * Define -DFIXTOUPPER for nonANSI C libraries that mess + up toupper/tolower + = No command-line changes; callers of readseq main() should be okay + - ureadseq.h functions have changed; client programs need to note. + + added Unix and VMS Make scripts, including validation tests + + 4 May 92. + added 32 bit CRC checksum as alternative to GCG 6.5bit checksum + (-DBIGCHECKSUM) + Aug 92 = fixed Olsen format input to handle files w/ more sequences, + not to mess up when more than one seq has same identifier, + and to convert number masks to symbols. + = IG format fix to understand ^L + + 25-30 Dec 92 + * revised command-line & interactive interface. Suggested form is now + readseq infile -format=genbank -output=outfile -item=1,3,4 ... + but remains compatible with prior commandlines: + readseq infile -f2 -ooutfile -i3 ... + + added GCG MSF multi sequence file format + + added PIR/CODATA format + + added NCBI ASN.1 sequence file format + + added Pretty, multi sequence pretty output (only) + + added PAUP multi seq format + + added degap option + + added Gary Williams (GWW, G.Williams@CRC.AC.UK) reverse-complement option. + + added support for reading Phylip formats (interleave & sequential) + * string fixes, dropped need for compiler flags NOSTR, FIXTOUPPER, NEEDSTRCASECMP + * changed 32bit checksum to default, -DSMALLCHECKSUM for GCG version + + 1Feb93 + = revert GenBank output to a fixed left number width which + other software depends on. + = fix for MSF input to handle symbols in names + = fix bug for possible memory overrun when truncating seqs for + Phylip or Paup formats (thanks Anthony Persechini) + 29 April 93 + * added a comma free output format for the Vienna RNA Package + + */ + + + +/* + Readseq has been tested with: + Macintosh MPW C + GNU gcc + SGI cc + VAX-VMS cc + Any ANSI C compiler should be able to handle this. + Old-style C compilers barf all over the source. + + +How do I build the readseq program if I have an Ansi C compiler? +#-------------------- +# Unix ANSI C +# Use the supplied Makefile this way: +% make CC=name-of-c-compiler +# OR do this... +% gcc readseq.c ureadseq.c -o readseq + +#-------------------- +$!VAX-VMS cc +$! Use the supplied Make.Com this way: +$ @make +$! OR, do this: +$ cc readseq, ureadseq +$ link readseq, ureadseq, sys$library:vaxcrtl/lib +$ readseq :== $ MyDisk:[myacct]readseq + +#-------------------- +# Macintosh Simple Input/Output Window application +# requires MPW-C and SIOW library (from APDA) +# also uses files macinit.c, macinit.r, readseqSIOW.make +# +Buildprogram readseqSIOW + +#-------------------- +#MPW-C v3 tool +C ureadseq.c +C readseq.c +link -w -o readseq -t MPST -c 'MPS ' ¶ + readseq.c.o Ureadseq.c.o ¶ + "{Libraries}"Interface.o ¶ + "{Libraries}"ToolLibs.o ¶ + "{Libraries}"Runtime.o ¶ + "{CLibraries}"StdClib.o +readseq -i1 ig.seq + +# MPW-C with NCBI tools + +set NCBI "{Boot}@molbio:ncbi:"; EXPORT NCBI +set NCBILIB1 "{NCBI}"lib:libncbi.o; export NCBILIB1 +set NCBILIB2 "{NCBI}"lib:libncbiobj.o; export NCBILIB2 +set NCBILIB3 "{NCBI}"lib:libncbicdr.o; export NCBILIB3 +set NCBILIB4 "{NCBI}"lib:libvibrant.o; export NCBILIB4 + +C ureadseq.c +C -d NCBI -i "{NCBI}"include: ureadasn.c +C -d NCBI -i "{NCBI}"include: readseq.c +link -w -o readseq -t MPST -c 'MPS ' ¶ + ureadseq.c.o ureadasn.c.o readseq.c.o ¶ + {NCBILIB4} {NCBILIB2} {NCBILIB1} ¶ + "{Libraries}"Interface.o ¶ + "{Libraries}"ToolLibs.o ¶ + "{Libraries}"Runtime.o ¶ + "{CLibraries}"CSANELib.o ¶ + "{CLibraries}"Math.o ¶ + "{CLibraries}"StdClib.o + +===========================================================*/ + + + +#include +#include +#include + +#include "ureadseq.h" + +#pragma segment readseq + + + +static char inputfilestore[256], *inputfile = inputfilestore; + +const char *formats[kMaxFormat+1] = { + " 1. IG/Stanford", + " 2. GenBank/GB", + " 3. NBRF", + " 4. EMBL", + " 5. GCG", + " 6. DNAStrider", + " 7. Fitch", + " 8. Pearson/Fasta", + " 9. Zuker (in-only)", + "10. Olsen (in-only)", + "11. Phylip3.2", + "12. Phylip", + "13. Plain/Raw", + "14. PIR/CODATA", + "15. MSF", + "16. ASN.1", + "17. PAUP/NEXUS", + "18. Pretty (out-only)", + "19. Vienna (out-only)", + "" }; + +#define kFormCount 31 +#define kMaxFormName 15 + +const struct formatTable { + char *name; + short num; + } formname[] = { + {"ig", kIG}, + {"stanford", kIG}, + {"genbank", kGenBank}, + {"gb", kGenBank}, + {"nbrf", kNBRF}, + {"embl", kEMBL}, + {"gcg", kGCG}, + {"uwgcg", kGCG}, + {"dnastrider", kStrider}, + {"strider", kStrider}, + {"fitch", kFitch}, + {"pearson", kPearson}, + {"fasta", kPearson}, + {"zuker", kZuker}, + {"olsen", kOlsen}, + {"phylip", kPhylip}, + {"phylip3.2", kPhylip2}, + {"phylip3.3", kPhylip3}, + {"phylip3.4", kPhylip4}, + {"phylip-interleaved", kPhylip4}, + {"phylip-sequential", kPhylip2}, + {"plain", kPlain}, + {"raw", kPlain}, + {"pir", kPIR}, + {"codata", kPIR}, + {"asn.1", kASN1}, + {"msf", kMSF}, + {"paup", kPAUP}, + {"nexus", kPAUP}, + {"pretty", kPretty}, + {"vienna", kVienna}, + }; + +const char *kASN1headline = "Bioseq-set ::= {\nseq-set {\n"; + +/* GWW table for getting the complement of a nucleotide (IUB codes) */ +/* ! "#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[ \]^_`abcdefghijklmnopqrstuvwxyz{|}~ */ +const char compl[] = " !\"#$%&'()*+,-./0123456789:;<=>?@TVGHNNCDNNMNKNNYRYSAABWNRN[\\]^_`tvghnncdnnmnknnyrysaabwnrn{|}~"; + + + +char *formatstr( short format) +{ + if (format < 1 || format > kMaxFormat) { + switch (format) { + case kASNseqentry : + case kASNseqset : return formats[kASN1-1]; + case kPhylipInterleave: + case kPhylipSequential: return formats[kPhylip-1]; + default: return "(unknown)"; + } + } + else return formats[format-1]; +} + +int parseformat( char *name) +{ +#define kDupmatch -2 + int namelen, maxlen, i, match, matchat; + char lname[kMaxFormName+1]; + + skipwhitespace(name); + namelen = strlen(name); + if (namelen == 0) + return kNoformat; + else if (isdigit(*name)) { + i = atol( name); + if (i < kMinFormat | i > kMaxFormat) return kNoformat; + else return i; + } + + /* else match character name */ + maxlen = min( kMaxFormName, namelen); + for (i=0; i out.seq\n"); + fprintf(stderr," options\n"); +/* ? add -d[igits] to allow digits in sequence data, &/or option to specify seq charset !? */ + fprintf(stderr, " -a[ll] select All sequences\n"); + fprintf(stderr, " -c[aselower] change to lower case\n"); + fprintf(stderr, " -C[ASEUPPER] change to UPPER CASE\n"); + fprintf(stderr, " -degap[=-] remove gap symbols\n"); + fprintf(stderr, " -i[tem=2,3,4] select Item number(s) from several\n"); + fprintf(stderr, " -l[ist] List sequences only\n"); + fprintf(stderr, " -o[utput=]out.seq redirect Output\n"); + fprintf(stderr, " -p[ipe] Pipe (command line, stdout)\n"); + fprintf(stderr, " -r[everse] change to Reverse-complement\n"); + fprintf(stderr, " -v[erbose] Verbose progress\n"); + fprintf(stderr, " -f[ormat=]# Format number for output, or\n"); + fprintf(stderr, " -f[ormat=]Name Format name for output:\n"); + midi = (kMaxFormat+1) / 2; + for (i = kMinFormat-1; i < midi; i++) + fprintf( stderr, " %-20s %-20s\n", + formats[i], formats[midi+i]); + + /* new output format options, esp. for pretty format: */ + fprintf(stderr, " \n"); + fprintf(stderr, " Pretty format options: \n"); + fprintf(stderr, " -wid[th]=# sequence line width\n"); + fprintf(stderr, " -tab=# left indent\n"); + fprintf(stderr, " -col[space]=# column space within sequence line on output\n"); + fprintf(stderr, " -gap[count] count gap chars in sequence numbers\n"); + fprintf(stderr, " -nameleft, -nameright[=#] name on left/right side [=max width]\n"); + fprintf(stderr, " -nametop name at top/bottom\n"); + fprintf(stderr, " -numleft, -numright seq index on left/right side\n"); + fprintf(stderr, " -numtop, -numbot index on top/bottom\n"); + fprintf(stderr, " -match[=.] use match base for 2..n species\n"); + fprintf(stderr, " -inter[line=#] blank line(s) between sequence blocks\n"); + + /****** not ready yet + fprintf(stderr, " -code=none,rtf,postscript,ps code syntax\n"); + fprintf(stderr, " -namefont=, -numfont=, -seqfont=font font choice\n"); + fprintf(stderr, " font suggestions include times,courier,helvetica\n"); + fprintf(stderr, " -namefontsize=, -numfontsize=, -seqfontsize=#\n"); + fprintf(stderr, " fontsize suggestions include 9,10,12,14\n"); + fprintf(stderr, " -namefontstyle=, -numfontstyle=, -seqfontstyle= style fontstyle for names\n"); + fprintf(stderr, " fontstyle options are plain,italic,bold,bold-italic\n"); + ******/ +} + +void erralert(short err) +{ + switch (err) { + case 0 : + break; + case eFileNotFound: fprintf(stderr, "File not found: %s\n", inputfile); + break; + case eFileCreate: fprintf(stderr, "Can't open output file.\n"); + break; + case eASNerr: fprintf(stderr, "Error in ASN.1 sequence routines.\n"); + break; + case eNoData: fprintf(stderr, "No data in file.\n"); + break; + case eItemNotFound: fprintf(stderr, "Specified item not in file.\n"); + break; + case eUnequalSize: fprintf(stderr, + "This format requires equal length sequences.\nSequence truncated or padded to fit.\n"); + break; + case eUnknownFormat: fprintf(stderr, "Error: this format is unknown to me.\n"); + break; + case eOneFormat: fprintf(stderr, + "Warning: This format permits only 1 sequence per file.\n"); + break; + case eMemFull: fprintf(stderr, "Out of storage memory. Sequence truncated.\n"); + break; + default: fprintf(stderr, "readSeq error = %d\n", err); + break; + } +} /* erralert */ + + +int chooseFormat( boolean quietly) +{ + char sform[128]; + int midi, i, outform; + + if (quietly) + return kPearson; /* default */ + else { + midi = (kMaxFormat+1) / 2; + for (i = kMinFormat-1; i < midi; i++) + fprintf( stderr, " %-20s %-20s\n", + formats[i], formats[midi+i]); + fprintf(stderr,"\nChoose an output format (name or #): \n"); + gets(sform); + outform = parseformat(sform); + if (outform == kNoformat) outform = kPearson; + return outform; + } +} + + + +/* read paramater(s) */ + +boolean checkopt( boolean casesense, char *sopt, const char *smatch, short minword) +{ + long lenopt, lenmatch; + boolean result; + short minmaxw; + + lenopt = strlen(sopt); + lenmatch= strlen(smatch); + minmaxw= max(minword, min(lenopt, lenmatch)); + + if (casesense) + result= (!strncmp( sopt, smatch, minmaxw)); + else + result= (!Strncasecmp( sopt, smatch, minmaxw )); + /* if (result) { */ + /* fprintf(stderr,"true checkopt(opt=%s,match=%s,param=%s)\n", sopt, smatch, *sparam); */ + /* } */ + return result; +} + + +#define kMaxwhichlist 50 + +/* global for readopt(), main() */ +boolean chooseall = false, quietly = false, gotinputfile = false, + listonly = false, closeout = false, verbose = false, + manyout = false, dolower = false, doupper = false, doreverse= false, + askout = true, dopipe= false, interleaved = false; +short nfile = 0, iwhichlist=0, nwhichlist = 0; +short whichlist[kMaxwhichlist+1]; +long whichSeq = 0, outform = kNoformat; +char onamestore[128], *oname = onamestore; +FILE *foo = NULL; + +void resetGlobals() +/* need this when used from SIOW, as these globals are not reinited automatically +between calls to local main() */ +{ + chooseall = false; quietly = false; gotinputfile = false; + listonly = false; closeout = false; verbose = false; + manyout = false; dolower = false; doupper = false; doreverse= false; + askout = true; dopipe= false; interleaved = false; + nfile = 0; iwhichlist=0; nwhichlist = 0; + whichSeq = 0; outform = kNoformat; + oname = onamestore; + foo = NULL; + + gPrettyInit(gPretty); +} + + +#define kOptOkay 1 +#define kOptNone 0 + +int readopt( char *sopt) +{ + char sparamstore[256], *sparam= sparamstore; + short n, slen= strlen(sopt); + + /* fprintf(stderr,"readopt( %s) == ", sopt); */ + + if (*sopt == '?') { + usage(); + return kOptNone; /*? eOptionBad or kOptNone */ + } + + else if (*sopt == '-') { + + char *cp= strchr(sopt,'='); + *sparam= '\0'; + if (cp) { + strcpy(sparam, cp+1); + *cp= 0; + } + + if (checkopt( false, sopt, "-help", 2)) { + usage(); + return kOptNone; + } + + if (checkopt( false, sopt, "-all", 2)) { + whichSeq= 1; chooseall= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-colspace", 4)) { /* test before -c[ase] */ + n= atoi( sparam); + gPretty.spacer = n; + return kOptOkay; + } + + if (checkopt( true, sopt, "-caselower", 2)) { + dolower= true; + return kOptOkay; + } + if (checkopt( true, sopt, "-CASEUPPER", 2)) { + doupper= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-pipe", 2)) { + dopipe= true; askout= false; + return kOptOkay; + } + + if (checkopt( false, sopt, "-list", 2)) { + listonly = true; askout = false; + return kOptOkay; + } + + if (checkopt( false, sopt, "-reverse", 2)) { + doreverse = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-verbose", 2)) { + verbose = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-match", 5)) { + gPretty.domatch= true; + if (*sparam >= ' ') gPretty.matchchar= *sparam; + return kOptOkay; + } + if (checkopt( false, sopt, "-degap", 4)) { + gPretty.degap= true; + if (*sparam >= ' ') gPretty.gapchar= *sparam; + return kOptOkay; + } + + if (checkopt( false, sopt, "-interline", 4)) { + gPretty.interline= atoi( sparam); + return kOptOkay; + } + + if (checkopt( false, sopt, "-item", 2)) { + char *cp = sparam; + nwhichlist= 0; + whichlist[0]= 0; + if (*cp == 0) cp= sopt+2; /* compatible w/ old way */ + do { + while (*cp!=0 && !isdigit(*cp)) cp++; + if (*cp!=0) { + n = atoi( cp); + whichlist[nwhichlist++]= n; + while (*cp!=0 && isdigit(*cp)) cp++; + } + } while (*cp!=0 && n>0 && nwhichlist0) gPretty.seqwidth = n; + return kOptOkay; + } + + if (checkopt( false, sopt, "-tab", 4)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + gPretty.tab = n; + return kOptOkay; + } + + if (checkopt( false, sopt, "-gapcount", 4)) { + gPretty.baseonlynum = false; + /* if (*sparam >= ' ') gPretty.gapchar= *sparam; */ + return kOptOkay; + } + if (checkopt( false, sopt, "-nointerleave", 8)) { + gPretty.noleaves = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-nameleft", 7)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.namewidth = n; + gPretty.nameleft= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-nameright", 7)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.namewidth = n; + gPretty.nameright= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-nametop", 6)) { + gPretty.nametop= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-numleft", 6)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.numwidth = n; + gPretty.numleft= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-numright", 6)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.numwidth = n; + gPretty.numright= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-numtop", 6)) { + gPretty.numtop= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-numbottom", 6)) { + gPretty.numbot= true; + return kOptOkay; + } + + else { + usage(); + return eOptionBad; + } + } + + else { + strcpy( inputfile, sopt); + gotinputfile = (*inputfile != 0); + nfile++; + return kOptOkay; + } + + /* return kOptNone; -- never here */ +} + + + + +/* this program suffers some as it tries to be a quiet translator pipe + _and_ a noisy user interactor +*/ + +/* return is best for SIOW, okay for others */ +#ifdef SIOW +#define Exit(a) return(a) +siow_main( int argc, char *argv[]) + +#else +#define Exit(a) exit(a) + +main( int argc, char *argv[]) +#endif +{ +boolean closein = false; +short ifile, nseq, atseq, format, err = 0, seqtype = kDNA, + nlines, seqout = 0, phylvers = 2; +long i, skiplines, seqlen, seqlen0; +unsigned long checksum= 0, checkall= 0; +char *seq, *cp, *firstseq = NULL, *seqlist, *progname, tempname[256]; +char seqid[256], *seqidptr = seqid; +char stempstore[256], *stemp = stempstore; +FILE *ftmp, *fin, *fout; +long outindexmax= 0, noutindex= 0, *outindex = NULL; + +#define exit_main(err) { \ + if (closeout) fclose(fout); \ + if (closein) fclose(fin); \ + if (*tempname!=0) remove(tempname);\ + Exit(err); } + +#define indexout() if (interleaved) {\ + if (noutindex>=outindexmax) {\ + outindexmax= noutindex + 20;\ + outindex= (long*) realloc(outindex, sizeof(long)*outindexmax);\ + if (outindex==NULL) { err= eMemFull; erralert(err); exit_main(err); }\ + }\ + outindex[noutindex++]= ftell(fout);\ + } + + + resetGlobals(); + foo = stdout; + progname = argv[0]; + *oname = 0; + *tempname = 0; + /* initialize gPretty ?? -- done in header */ + + for (i=1; i < argc; i++) { + err= readopt( argv[i]); + if (err <= 0) exit_main(err); + } + + /* pipe input from stdin !? */ + if (dopipe && !gotinputfile) { + int c; + tmpnam(tempname); + inputfile = tempname; + ftmp = fopen( inputfile, "w"); + if (!ftmp) { erralert(eFileCreate); exit_main(eFileCreate); } + while ((c = getc(stdin)) != EOF) fputc(c, ftmp); + fclose(ftmp); + gotinputfile= true; + } + + quietly = (dopipe || (gotinputfile && (listonly || whichSeq != 0))); + + if (verbose || (!quietly && !gotinputfile)) fprintf( stderr, title); + ifile = 1; + + /* UI: Choose output */ + if (askout && !closeout && !quietly) { + askout = false; + fprintf(stderr,"\nName of output file (?=help, defaults to display): \n"); + gets(oname= onamestore); + skipwhitespace(oname); + if (*oname == '?') { usage(); exit_main(0); } + else if (*oname != 0) { + closeout = true; + foo = fopen( oname, "w"); + if (!foo) { erralert(eFileCreate); exit_main(eFileCreate); } + } + } + + fout = foo; + if (outform == kNoformat) outform = chooseFormat(quietly); + + /* set up formats ... */ + switch (outform) { + case kPhylip2: + interleaved= false; + phylvers = 2; + outform = kPhylip; + break; + + case kPhylip4: + interleaved= true; + phylvers = 4; + outform = kPhylip; + break; + + case kMSF: + case kPAUP: + interleaved= true; + break; + + case kPretty: + gPretty.isactive= true; + interleaved= true; + break; + + } + + if (gPretty.isactive && gPretty.noleaves) interleaved= false; + if (interleaved) { + fout = ftmp = tmpfile(); + outindexmax= 30; noutindex= 0; + outindex = (long*) malloc(outindexmax*sizeof(long)); + if (outindex==NULL) { err= eMemFull; erralert(err); exit_main(err); } + } + + /* big loop over all input files */ + do { + /* select next input file */ + gotinputfile = (*tempname != 0); + while ((ifile < argc) && (!gotinputfile)) { + if (*argv[ifile] != '-') { + strcpy( inputfile, argv[ifile]); + gotinputfile = (*inputfile != 0); + --nfile; + } + ifile++; + } + + while (!gotinputfile) { + fprintf(stderr,"\nName an input sequence or -option: \n"); + inputfile= inputfilestore; + + gets(stemp= stempstore); + if (*stemp==0) goto fini; /* !! need this to finish work during interactive use */ + stemp= strtok(stempstore, " \n\r\t"); + while (stemp) { + err= readopt( stemp); /* will read inputfile if it exists */ + if (err<0) exit_main(err); + stemp= strtok( NULL, " \n\r\t"); + } + } + /* thanks to AJB@UK.AC.DARESBURY.DLVH for this PHYLIP3 fix: */ + /* head for end (interleave if needed) */ + if (*inputfile == 0) break; + + format = seqFileFormat( inputfile, &skiplines, &err); + + if (err == 0) { +#ifdef NCBI + if (format == kASNseqentry || format == kASNseqset) + seqlist = listASNSeqs( inputfile, skiplines, format, &nseq, &err); + else +#endif + seqlist = listSeqs( inputfile, skiplines, format, &nseq, &err); + } + + if (err != 0) + erralert(err); + + else if (listonly) { + dumpSeqList(seqlist,format); + free( seqlist); + } + + else { + /* choose whichSeq if needed */ + if (nseq == 1 || chooseall || (quietly && whichSeq == 0)) { + chooseall= true; + whichSeq = 1; + quietly = true; /* no loop */ + } + else if (whichSeq > nseq && quietly) { + erralert(eItemNotFound); + err= eItemNotFound; + } + else if (whichSeq > nseq || !quietly) { + dumpSeqList(seqlist, format); + fprintf(stderr,"\nChoose a sequence (# or All): \n"); + gets(stemp= stempstore); + skipwhitespace(stemp); + if (to_lower(*stemp) == 'a') { + chooseall= true; + whichSeq = 1; + quietly = true; /* !? this means we don't ask for another file + as well as no more whichSeqs... */ + } + else if (isdigit(*stemp)) whichSeq= atol(stemp); + else whichSeq= 1; /* default */ + } + free( seqlist); + + if (false /*chooseall*/) { /* this isn't debugged yet...*/ + fin = fopen(inputfile, "r"); + closein= true; + } + + while (whichSeq > 0 && whichSeq <= nseq) { + /* need to open multiple output files ? */ + manyout = ((chooseall || nwhichlist>1) && nseq > 1 + && (outform == kPlain || outform == kGCG)); + if (manyout) { + if ( whichSeq == 1 ) erralert(eOneFormat); + else if (closeout) { + sprintf( stemp,"%s_%d", oname, whichSeq); + freopen( stemp, "w", fout); + fprintf( stderr,"Writing sequence %d to file %s\n", whichSeq, stemp); + } + } + + if (closein) { + /* !! this fails... skips most seqs... */ + /* !! in sequential read, must count seqs already read from whichSeq ... */ + /* need major revision of ureadseq before we can do this */ + atseq= whichSeq-1; + seqidptr= seqid; + seq = readSeqFp( whichSeq, fin, skiplines, format, + &seqlen, &atseq, &err, seqidptr); + skiplines= 0; + } + else { + atseq= 0; + seqidptr= seqid; +#ifdef NCBI + if (format == kASNseqentry || format == kASNseqset) { + seqidptr= NULL; + seq = readASNSeq( whichSeq, inputfile, skiplines, format, + &seqlen, &atseq, &err, &seqidptr); + } + else +#endif + seq = readSeq( whichSeq, inputfile, skiplines, format, + &seqlen, &atseq, &err, seqidptr); + } + + + if (gPretty.degap) { + char *newseq; + long newlen; + newseq= compressSeq( gPretty.gapchar, seq, seqlen, &newlen); + if (newseq) { + free(seq); seq= newseq; seqlen= newlen; + } + } + + if (outform == kMSF) checksum= GCGchecksum(seq, seqlen, &checkall); + else if (verbose) checksum= seqchecksum(seq, seqlen, &checkall); + if (verbose) + fprintf( stderr, "Sequence %d, length= %d, checksum= %X, format= %s, id= %s\n", + whichSeq, seqlen, checksum, formatstr(format), seqidptr); + + if (err != 0) erralert(err); + else { + /* format fixes that writeseq doesn't do */ + switch (outform) { + case kPIR: + if (seqout == 0) fprintf( foo,"\\\\\\\n"); + break; + case kASN1: + if (seqout == 0) fprintf( foo, kASN1headline); + break; + + case kPhylip: + if (seqout == 0) { + if (!interleaved) { /* bug, nseq is for 1st infile only */ + if (chooseall) i= nseq; else i=1; + if (phylvers >= 4) fprintf(foo," %d %d\n", i, seqlen); + else fprintf(foo," %d %d YF\n", i, seqlen); + } + seqlen0 = seqlen; + } + else if (seqlen != seqlen0) { + erralert(eUnequalSize); + if (seqlen < seqlen0) seq = (char *)realloc(seq, seqlen0); + for (i=seqlen; i 0 || !quietly); + + +fini: + if (firstseq) { free(firstseq); firstseq= NULL; } + if (err || listonly) exit_main(err); + + if (gPretty.isactive && gPretty.numbot) { + gPretty.numline = 2; + indexout(); + (void) writeSeq( fout, seq, seqlen, outform, seqidptr); + gPretty.numline = 1; + indexout(); + (void) writeSeq( fout, seq, seqlen, outform, seqidptr); + gPretty.numline = 0; + } + + if (outform == kMSF) { + if (*oname) cp= oname; else cp= inputfile; + fprintf(foo,"\n %s MSF: %d Type: N January 01, 1776 12:00 Check: %d ..\n\n", + cp, seqlen, checkall); + } + + if (outform == kPAUP) { + fprintf(foo,"#NEXUS\n"); + if (*oname) cp= oname; else cp= inputfile; + fprintf(foo,"[%s -- data title]\n\n", cp); + /* ! now have header lines for each sequence... put them before "begin data;... */ + } + + if (outform==kPhylip && interleaved) { + if (phylvers >= 4) fprintf(foo," %d %d\n", seqout, seqlen); + else fprintf(foo," %d %d YF\n", seqout, seqlen); + } + + if (interleaved) { + /* interleave species lines in true output */ + /* nlines is # lines / sequence */ + short iline, j, leaf, iseq; + char *s = stempstore; + + indexout(); noutindex--; /* mark eof */ + + for (leaf=0; leaf +#include +#include + +#include "ureadseq.h" + +#pragma segment readseq + + + +static char inputfilestore[256], *inputfile = inputfilestore; + +const char *formats[kMaxFormat+1] = { + " 1. IG/Stanford", + " 2. GenBank/GB", + " 3. NBRF", + " 4. EMBL", + " 5. GCG", + " 6. DNAStrider", + " 7. Fitch", + " 8. Pearson/Fasta", + " 9. Zuker (in-only)", + "10. Olsen (in-only)", + "11. Phylip3.2", + "12. Phylip", + "13. Plain/Raw", + "14. PIR/CODATA", + "15. MSF", + "16. ASN.1", + "17. PAUP/NEXUS", + "18. Pretty (out-only)", + "" }; + +#define kFormCount 30 +#define kMaxFormName 15 + +const struct formatTable { + char *name; + short num; + } formname[] = { + {"ig", kIG}, + {"stanford", kIG}, + {"genbank", kGenBank}, + {"gb", kGenBank}, + {"nbrf", kNBRF}, + {"embl", kEMBL}, + {"gcg", kGCG}, + {"uwgcg", kGCG}, + {"dnastrider", kStrider}, + {"strider", kStrider}, + {"fitch", kFitch}, + {"pearson", kPearson}, + {"fasta", kPearson}, + {"zuker", kZuker}, + {"olsen", kOlsen}, + {"phylip", kPhylip}, + {"phylip3.2", kPhylip2}, + {"phylip3.3", kPhylip3}, + {"phylip3.4", kPhylip4}, + {"phylip-interleaved", kPhylip4}, + {"phylip-sequential", kPhylip2}, + {"plain", kPlain}, + {"raw", kPlain}, + {"pir", kPIR}, + {"codata", kPIR}, + {"asn.1", kASN1}, + {"msf", kMSF}, + {"paup", kPAUP}, + {"nexus", kPAUP}, + {"pretty", kPretty}, + }; + +const char *kASN1headline = "Bioseq-set ::= {\nseq-set {\n"; + +/* GWW table for getting the complement of a nucleotide (IUB codes) */ +/* ! "#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[ \]^_`abcdefghijklmnopqrstuvwxyz{|}~ */ +const char compl[] = " !\"#$%&'()*+,-./0123456789:;<=>?@TVGHNNCDNNMNKNNYRYSAABWNRN[\\]^_`tvghnncdnnmnknnyrysaabwnrn{|}~"; + + + +char *formatstr( short format) +{ + if (format < 1 || format > kMaxFormat) { + switch (format) { + case kASNseqentry : + case kASNseqset : return formats[kASN1-1]; + case kPhylipInterleave: + case kPhylipSequential: return formats[kPhylip-1]; + default: return "(unknown)"; + } + } + else return formats[format-1]; +} + +int parseformat( char *name) +{ +#define kDupmatch -2 + int namelen, maxlen, i, match, matchat; + char lname[kMaxFormName+1]; + + skipwhitespace(name); + namelen = strlen(name); + if (namelen == 0) + return kNoformat; + else if (isdigit(*name)) { + i = atol( name); + if (i < kMinFormat | i > kMaxFormat) return kNoformat; + else return i; + } + + /* else match character name */ + maxlen = min( kMaxFormName, namelen); + for (i=0; i out.seq\n"); + fprintf(stderr," options\n"); +/* ? add -d[igits] to allow digits in sequence data, &/or option to specify seq charset !? */ + fprintf(stderr, " -a[ll] select All sequences\n"); + fprintf(stderr, " -c[aselower] change to lower case\n"); + fprintf(stderr, " -C[ASEUPPER] change to UPPER CASE\n"); + fprintf(stderr, " -degap[=-] remove gap symbols\n"); + fprintf(stderr, " -i[tem=2,3,4] select Item number(s) from several\n"); + fprintf(stderr, " -l[ist] List sequences only\n"); + fprintf(stderr, " -o[utput=]out.seq redirect Output\n"); + fprintf(stderr, " -p[ipe] Pipe (command line, stdout)\n"); + fprintf(stderr, " -r[everse] change to Reverse-complement\n"); + fprintf(stderr, " -v[erbose] Verbose progress\n"); + fprintf(stderr, " -f[ormat=]# Format number for output, or\n"); + fprintf(stderr, " -f[ormat=]Name Format name for output:\n"); + midi = (kMaxFormat+1) / 2; + for (i = kMinFormat-1; i < midi; i++) + fprintf( stderr, " %-20s %-20s\n", + formats[i], formats[midi+i]); + + /* new output format options, esp. for pretty format: */ + fprintf(stderr, " \n"); + fprintf(stderr, " Pretty format options: \n"); + fprintf(stderr, " -wid[th]=# sequence line width\n"); + fprintf(stderr, " -tab=# left indent\n"); + fprintf(stderr, " -col[space]=# column space within sequence line on output\n"); + fprintf(stderr, " -gap[count] count gap chars in sequence numbers\n"); + fprintf(stderr, " -nameleft, -nameright[=#] name on left/right side [=max width]\n"); + fprintf(stderr, " -nametop name at top/bottom\n"); + fprintf(stderr, " -numleft, -numright seq index on left/right side\n"); + fprintf(stderr, " -numtop, -numbot index on top/bottom\n"); + fprintf(stderr, " -match[=.] use match base for 2..n species\n"); + fprintf(stderr, " -inter[line=#] blank line(s) between sequence blocks\n"); + + /****** not ready yet + fprintf(stderr, " -code=none,rtf,postscript,ps code syntax\n"); + fprintf(stderr, " -namefont=, -numfont=, -seqfont=font font choice\n"); + fprintf(stderr, " font suggestions include times,courier,helvetica\n"); + fprintf(stderr, " -namefontsize=, -numfontsize=, -seqfontsize=#\n"); + fprintf(stderr, " fontsize suggestions include 9,10,12,14\n"); + fprintf(stderr, " -namefontstyle=, -numfontstyle=, -seqfontstyle= style fontstyle for names\n"); + fprintf(stderr, " fontstyle options are plain,italic,bold,bold-italic\n"); + ******/ +} + +void erralert(short err) +{ + switch (err) { + case 0 : + break; + case eFileNotFound: fprintf(stderr, "File not found: %s\n", inputfile); + break; + case eFileCreate: fprintf(stderr, "Can't open output file.\n"); + break; + case eASNerr: fprintf(stderr, "Error in ASN.1 sequence routines.\n"); + break; + case eNoData: fprintf(stderr, "No data in file.\n"); + break; + case eItemNotFound: fprintf(stderr, "Specified item not in file.\n"); + break; + case eUnequalSize: fprintf(stderr, + "This format requires equal length sequences.\nSequence truncated or padded to fit.\n"); + break; + case eUnknownFormat: fprintf(stderr, "Error: this format is unknown to me.\n"); + break; + case eOneFormat: fprintf(stderr, + "Warning: This format permits only 1 sequence per file.\n"); + break; + case eMemFull: fprintf(stderr, "Out of storage memory. Sequence truncated.\n"); + break; + default: fprintf(stderr, "readSeq error = %d\n", err); + break; + } +} /* erralert */ + + +int chooseFormat( boolean quietly) +{ + char sform[128]; + int midi, i, outform; + + if (quietly) + return kPearson; /* default */ + else { + midi = (kMaxFormat+1) / 2; + for (i = kMinFormat-1; i < midi; i++) + fprintf( stderr, " %-20s %-20s\n", + formats[i], formats[midi+i]); + fprintf(stderr,"\nChoose an output format (name or #): \n"); + gets(sform); + outform = parseformat(sform); + if (outform == kNoformat) outform = kPearson; + return outform; + } +} + + + +/* read paramater(s) */ + +boolean checkopt( boolean casesense, char *sopt, const char *smatch, short minword) +{ + long lenopt, lenmatch; + boolean result; + short minmaxw; + + lenopt = strlen(sopt); + lenmatch= strlen(smatch); + minmaxw= max(minword, min(lenopt, lenmatch)); + + if (casesense) + result= (!strncmp( sopt, smatch, minmaxw)); + else + result= (!Strncasecmp( sopt, smatch, minmaxw )); + /* if (result) { */ + /* fprintf(stderr,"true checkopt(opt=%s,match=%s,param=%s)\n", sopt, smatch, *sparam); */ + /* } */ + return result; +} + + +#define kMaxwhichlist 50 + +/* global for readopt(), main() */ +boolean chooseall = false, quietly = false, gotinputfile = false, + listonly = false, closeout = false, verbose = false, + manyout = false, dolower = false, doupper = false, doreverse= false, + askout = true, dopipe= false, interleaved = false; +short nfile = 0, iwhichlist=0, nwhichlist = 0; +short whichlist[kMaxwhichlist+1]; +long whichSeq = 0, outform = kNoformat; +char onamestore[128], *oname = onamestore; +FILE *foo = NULL; + +void resetGlobals() +/* need this when used from SIOW, as these globals are not reinited automatically +between calls to local main() */ +{ + chooseall = false; quietly = false; gotinputfile = false; + listonly = false; closeout = false; verbose = false; + manyout = false; dolower = false; doupper = false; doreverse= false; + askout = true; dopipe= false; interleaved = false; + nfile = 0; iwhichlist=0; nwhichlist = 0; + whichSeq = 0; outform = kNoformat; + oname = onamestore; + foo = NULL; + + gPrettyInit(gPretty); +} + + +#define kOptOkay 1 +#define kOptNone 0 + +int readopt( char *sopt) +{ + char sparamstore[256], *sparam= sparamstore; + short n, slen= strlen(sopt); + + /* fprintf(stderr,"readopt( %s) == ", sopt); */ + + if (*sopt == '?') { + usage(); + return kOptNone; /*? eOptionBad or kOptNone */ + } + + else if (*sopt == '-') { + + char *cp= strchr(sopt,'='); + *sparam= '\0'; + if (cp) { + strcpy(sparam, cp+1); + *cp= 0; + } + + if (checkopt( false, sopt, "-help", 2)) { + usage(); + return kOptNone; + } + + if (checkopt( false, sopt, "-all", 2)) { + whichSeq= 1; chooseall= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-colspace", 4)) { /* test before -c[ase] */ + n= atoi( sparam); + gPretty.spacer = n; + return kOptOkay; + } + + if (checkopt( true, sopt, "-caselower", 2)) { + dolower= true; + return kOptOkay; + } + if (checkopt( true, sopt, "-CASEUPPER", 2)) { + doupper= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-pipe", 2)) { + dopipe= true; askout= false; + return kOptOkay; + } + + if (checkopt( false, sopt, "-list", 2)) { + listonly = true; askout = false; + return kOptOkay; + } + + if (checkopt( false, sopt, "-reverse", 2)) { + doreverse = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-verbose", 2)) { + verbose = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-match", 5)) { + gPretty.domatch= true; + if (*sparam >= ' ') gPretty.matchchar= *sparam; + return kOptOkay; + } + if (checkopt( false, sopt, "-degap", 4)) { + gPretty.degap= true; + if (*sparam >= ' ') gPretty.gapchar= *sparam; + return kOptOkay; + } + + if (checkopt( false, sopt, "-interline", 4)) { + gPretty.interline= atoi( sparam); + return kOptOkay; + } + + if (checkopt( false, sopt, "-item", 2)) { + char *cp = sparam; + nwhichlist= 0; + whichlist[0]= 0; + if (*cp == 0) cp= sopt+2; /* compatible w/ old way */ + do { + while (*cp!=0 && !isdigit(*cp)) cp++; + if (*cp!=0) { + n = atoi( cp); + whichlist[nwhichlist++]= n; + while (*cp!=0 && isdigit(*cp)) cp++; + } + } while (*cp!=0 && n>0 && nwhichlist0) gPretty.seqwidth = n; + return kOptOkay; + } + + if (checkopt( false, sopt, "-tab", 4)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + gPretty.tab = n; + return kOptOkay; + } + + if (checkopt( false, sopt, "-gapcount", 4)) { + gPretty.baseonlynum = false; + /* if (*sparam >= ' ') gPretty.gapchar= *sparam; */ + return kOptOkay; + } + if (checkopt( false, sopt, "-nointerleave", 8)) { + gPretty.noleaves = true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-nameleft", 7)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.namewidth = n; + gPretty.nameleft= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-nameright", 7)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.namewidth = n; + gPretty.nameright= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-nametop", 6)) { + gPretty.nametop= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-numleft", 6)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.numwidth = n; + gPretty.numleft= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-numright", 6)) { + if (*sparam==0) { for (sparam= sopt+2; !isdigit(*sparam) && *sparam!=0; sparam++) ; } + n= atoi( sparam); + if (n>0 && n<50) gPretty.numwidth = n; + gPretty.numright= true; + return kOptOkay; + } + + if (checkopt( false, sopt, "-numtop", 6)) { + gPretty.numtop= true; + return kOptOkay; + } + if (checkopt( false, sopt, "-numbottom", 6)) { + gPretty.numbot= true; + return kOptOkay; + } + + else { + usage(); + return eOptionBad; + } + } + + else { + strcpy( inputfile, sopt); + gotinputfile = (*inputfile != 0); + nfile++; + return kOptOkay; + } + + /* return kOptNone; -- never here */ +} + + + + +/* this program suffers some as it tries to be a quiet translator pipe + _and_ a noisy user interactor +*/ + +/* return is best for SIOW, okay for others */ +#ifdef SIOW +#define Exit(a) return(a) +siow_main( int argc, char *argv[]) + +#else +#define Exit(a) exit(a) + +main( int argc, char *argv[]) +#endif +{ +boolean closein = false; +short ifile, nseq, atseq, format, err = 0, seqtype = kDNA, + nlines, seqout = 0, phylvers = 2; +long i, skiplines, seqlen, seqlen0; +unsigned long checksum= 0, checkall= 0; +char *seq, *cp, *firstseq = NULL, *seqlist, *progname, tempname[256]; +char seqid[256], *seqidptr = seqid; +char stempstore[256], *stemp = stempstore; +FILE *ftmp, *fin, *fout; +long outindexmax= 0, noutindex= 0, *outindex = NULL; + +#define exit_main(err) { \ + if (closeout) fclose(fout); \ + if (closein) fclose(fin); \ + if (*tempname!=0) remove(tempname);\ + Exit(err); } + +#define indexout() if (interleaved) {\ + if (noutindex>=outindexmax) {\ + outindexmax= noutindex + 20;\ + outindex= (long*) realloc(outindex, sizeof(long)*outindexmax);\ + if (outindex==NULL) { err= eMemFull; erralert(err); exit_main(err); }\ + }\ + outindex[noutindex++]= ftell(fout);\ + } + + + resetGlobals(); + foo = stdout; + progname = argv[0]; + *oname = 0; + *tempname = 0; + /* initialize gPretty ?? -- done in header */ + + for (i=1; i < argc; i++) { + err= readopt( argv[i]); + if (err <= 0) exit_main(err); + } + + /* pipe input from stdin !? */ + if (dopipe && !gotinputfile) { + int c; + tmpnam(tempname); + inputfile = tempname; + ftmp = fopen( inputfile, "w"); + if (!ftmp) { erralert(eFileCreate); exit_main(eFileCreate); } + while ((c = getc(stdin)) != EOF) fputc(c, ftmp); + fclose(ftmp); + gotinputfile= true; + } + + quietly = (dopipe || (gotinputfile && (listonly || whichSeq != 0))); + + if (verbose || (!quietly && !gotinputfile)) fprintf( stderr, title); + ifile = 1; + + /* UI: Choose output */ + if (askout && !closeout && !quietly) { + askout = false; + fprintf(stderr,"\nName of output file (?=help, defaults to display): \n"); + gets(oname= onamestore); + skipwhitespace(oname); + if (*oname == '?') { usage(); exit_main(0); } + else if (*oname != 0) { + closeout = true; + foo = fopen( oname, "w"); + if (!foo) { erralert(eFileCreate); exit_main(eFileCreate); } + } + } + + fout = foo; + if (outform == kNoformat) outform = chooseFormat(quietly); + + /* set up formats ... */ + switch (outform) { + case kPhylip2: + interleaved= false; + phylvers = 2; + outform = kPhylip; + break; + + case kPhylip4: + interleaved= true; + phylvers = 4; + outform = kPhylip; + break; + + case kMSF: + case kPAUP: + interleaved= true; + break; + + case kPretty: + gPretty.isactive= true; + interleaved= true; + break; + + } + + if (gPretty.isactive && gPretty.noleaves) interleaved= false; + if (interleaved) { + fout = ftmp = tmpfile(); + outindexmax= 30; noutindex= 0; + outindex = (long*) malloc(outindexmax*sizeof(long)); + if (outindex==NULL) { err= eMemFull; erralert(err); exit_main(err); } + } + + /* big loop over all input files */ + do { + /* select next input file */ + gotinputfile = (*tempname != 0); + while ((ifile < argc) && (!gotinputfile)) { + if (*argv[ifile] != '-') { + strcpy( inputfile, argv[ifile]); + gotinputfile = (*inputfile != 0); + --nfile; + } + ifile++; + } + + while (!gotinputfile) { + fprintf(stderr,"\nName an input sequence or -option: \n"); + inputfile= inputfilestore; + + gets(stemp= stempstore); + if (*stemp==0) goto fini; /* !! need this to finish work during interactive use */ + stemp= strtok(stempstore, " \n\r\t"); + while (stemp) { + err= readopt( stemp); /* will read inputfile if it exists */ + if (err<0) exit_main(err); + stemp= strtok( NULL, " \n\r\t"); + } + } + /* thanks to AJB@UK.AC.DARESBURY.DLVH for this PHYLIP3 fix: */ + /* head for end (interleave if needed) */ + if (*inputfile == 0) break; + + format = seqFileFormat( inputfile, &skiplines, &err); + + if (err == 0) { +#ifdef NCBI + if (format == kASNseqentry || format == kASNseqset) + seqlist = listASNSeqs( inputfile, skiplines, format, &nseq, &err); + else +#endif + seqlist = listSeqs( inputfile, skiplines, format, &nseq, &err); + } + + if (err != 0) + erralert(err); + + else if (listonly) { + dumpSeqList(seqlist,format); + free( seqlist); + } + + else { + /* choose whichSeq if needed */ + if (nseq == 1 || chooseall || (quietly && whichSeq == 0)) { + chooseall= true; + whichSeq = 1; + quietly = true; /* no loop */ + } + else if (whichSeq > nseq && quietly) { + erralert(eItemNotFound); + err= eItemNotFound; + } + else if (whichSeq > nseq || !quietly) { + dumpSeqList(seqlist, format); + fprintf(stderr,"\nChoose a sequence (# or All): \n"); + gets(stemp= stempstore); + skipwhitespace(stemp); + if (to_lower(*stemp) == 'a') { + chooseall= true; + whichSeq = 1; + quietly = true; /* !? this means we don't ask for another file + as well as no more whichSeqs... */ + } + else if (isdigit(*stemp)) whichSeq= atol(stemp); + else whichSeq= 1; /* default */ + } + free( seqlist); + + if (false /*chooseall*/) { /* this isn't debugged yet...*/ + fin = fopen(inputfile, "r"); + closein= true; + } + + while (whichSeq > 0 && whichSeq <= nseq) { + /* need to open multiple output files ? */ + manyout = ((chooseall || nwhichlist>1) && nseq > 1 + && (outform == kPlain || outform == kGCG)); + if (manyout) { + if ( whichSeq == 1 ) erralert(eOneFormat); + else if (closeout) { + sprintf( stemp,"%s_%d", oname, whichSeq); + freopen( stemp, "w", fout); + fprintf( stderr,"Writing sequence %d to file %s\n", whichSeq, stemp); + } + } + + if (closein) { + /* !! this fails... skips most seqs... */ + /* !! in sequential read, must count seqs already read from whichSeq ... */ + /* need major revision of ureadseq before we can do this */ + atseq= whichSeq-1; + seqidptr= seqid; + seq = readSeqFp( whichSeq, fin, skiplines, format, + &seqlen, &atseq, &err, seqidptr); + skiplines= 0; + } + else { + atseq= 0; + seqidptr= seqid; +#ifdef NCBI + if (format == kASNseqentry || format == kASNseqset) { + seqidptr= NULL; + seq = readASNSeq( whichSeq, inputfile, skiplines, format, + &seqlen, &atseq, &err, &seqidptr); + } + else +#endif + seq = readSeq( whichSeq, inputfile, skiplines, format, + &seqlen, &atseq, &err, seqidptr); + } + + + if (gPretty.degap) { + char *newseq; + long newlen; + newseq= compressSeq( gPretty.gapchar, seq, seqlen, &newlen); + if (newseq) { + free(seq); seq= newseq; seqlen= newlen; + } + } + + if (outform == kMSF) checksum= GCGchecksum(seq, seqlen, &checkall); + else if (verbose) checksum= seqchecksum(seq, seqlen, &checkall); + if (verbose) + fprintf( stderr, "Sequence %d, length= %d, checksum= %X, format= %s, id= %s\n", + whichSeq, seqlen, checksum, formatstr(format), seqidptr); + + if (err != 0) erralert(err); + else { + /* format fixes that writeseq doesn't do */ + switch (outform) { + case kPIR: + if (seqout == 0) fprintf( foo,"\\\\\\\n"); + break; + case kASN1: + if (seqout == 0) fprintf( foo, kASN1headline); + break; + + case kPhylip: + if (seqout == 0) { + if (!interleaved) { /* bug, nseq is for 1st infile only */ + if (chooseall) i= nseq; else i=1; + if (phylvers >= 4) fprintf(foo," %d %d\n", i, seqlen); + else fprintf(foo," %d %d YF\n", i, seqlen); + } + seqlen0 = seqlen; + } + else if (seqlen != seqlen0) { + erralert(eUnequalSize); + if (seqlen < seqlen0) seq = (char *)realloc(seq, seqlen0); + for (i=seqlen; i 0 || !quietly); + + +fini: + if (firstseq) { free(firstseq); firstseq= NULL; } + if (err || listonly) exit_main(err); + + if (gPretty.isactive && gPretty.numbot) { + gPretty.numline = 2; + indexout(); + (void) writeSeq( fout, seq, seqlen, outform, seqidptr); + gPretty.numline = 1; + indexout(); + (void) writeSeq( fout, seq, seqlen, outform, seqidptr); + gPretty.numline = 0; + } + + if (outform == kMSF) { + if (*oname) cp= oname; else cp= inputfile; + fprintf(foo,"\n %s MSF: %d Type: N January 01, 1776 12:00 Check: %d ..\n\n", + cp, seqlen, checkall); + } + + if (outform == kPAUP) { + fprintf(foo,"#NEXUS\n"); + if (*oname) cp= oname; else cp= inputfile; + fprintf(foo,"[%s -- data title]\n\n", cp); + /* ! now have header lines for each sequence... put them before "begin data;... */ + } + + if (outform==kPhylip && interleaved) { + if (phylvers >= 4) fprintf(foo," %d %d\n", seqout, seqlen); + else fprintf(foo," %d %d YF\n", seqout, seqlen); + } + + if (interleaved) { + /* interleave species lines in true output */ + /* nlines is # lines / sequence */ + short iline, j, leaf, iseq; + char *s = stempstore; + + indexout(); noutindex--; /* mark eof */ + + for (leaf=0; leafstdout)\n"); + fprintf(stderr, " -r[everse] change to Reverse-complement\n"); ++ #ifdef TRANSLATE ++ fprintf(stderr, " -t[ranslate=]io translate input symbol [i] to output symbol [o] \n"); ++ fprintf(stderr, " use several -tio to translate several symbols \n"); ++ #endif + fprintf(stderr, " -v[erbose] Verbose progress\n"); + fprintf(stderr, " -f[ormat=]# Format number for output, or\n"); + fprintf(stderr, " -f[ormat=]Name Format name for output:\n"); +*************** +*** 474,479 **** +--- 478,486 ---- + foo = NULL; + + gPrettyInit(gPretty); ++ #ifdef TRANSLATE ++ gTranslateInit(); ++ #endif + } + + +*************** +*** 590,595 **** +--- 597,615 ---- + outform = parseformat( sparam); + return kOptOkay; + } ++ ++ #ifdef TRANSLATE ++ if (checkopt( false, sopt, "-translate", 3)) {/* -translate=io */ ++ if (*sparam==0) { for (sparam= sopt+3; isalpha(*sparam); sparam++) ; } ++ if (*sparam) gTranslate[*sparam]= sparam[1]; ++ return kOptOkay; ++ } ++ if (checkopt( false, sopt, "-t", 2)) { /* shorthand is -tio */ ++ if (*sparam==0) sparam= sopt+2; ++ if (*sparam) gTranslate[*sparam]= sparam[1]; ++ return kOptOkay; ++ } ++ #endif + + if (checkopt( false, sopt, "-output", 3)) {/* -output=myseq */ + if (*sparam==0) { for (sparam= sopt+3; isalpha(*sparam); sparam++) ; } + + +diff -bwrc old/ureadseq.c rtrans/ureadseq.c +*** old/ureadseq.c Thu Dec 22 08:58:41 1994 +--- rtrans/ureadseq.c Thu Dec 22 09:01:43 1994 +*************** +*** 162,168 **** +--- 162,172 ---- + } + else V->seq = ptr; + } ++ #ifdef TRANSLATE ++ V->seq[(V->seqlen)++] = gTranslate[*s]; ++ #else + V->seq[(V->seqlen)++] = *s; ++ #endif + } + s++; + } + + +diff -bwrc old/ureadseq.h rtrans/ureadseq.h +*** old/ureadseq.h Thu Dec 22 08:58:41 1994 +--- rtrans/ureadseq.h Thu Dec 22 08:58:28 1994 +*************** +*** 113,118 **** +--- 113,126 ---- + extern prettyopts gPretty; + #endif + ++ #ifdef TRANSLATE ++ #ifdef UREADSEQ_G ++ char gTranslate[256]; ++ #else ++ extern char gTranslate[256]; ++ #endif ++ #define gTranslateInit() { short c; for(c=0; c<256; c++) gTranslate[c]= c; } ++ #endif + + #ifdef __cplusplus + extern "C" { diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/upper.std b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/upper.std new file mode 100755 index 00000000..3b8c3e42 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/upper.std @@ -0,0 +1,3 @@ +>alphabet['!'..'~'], 83 bases, 9429 checksum. +!"#$%&'()*+-./:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\] +^_`ABCDEFGHIJKLMNOPQRSTUVWXYZ{|}~ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadasn.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadasn.c new file mode 100755 index 00000000..8684aa56 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadasn.c @@ -0,0 +1,305 @@ +/* ureadasn.c + -- parse, mangle and otherwise rewrite ASN1 file/entries for readseq reading + -- from NCBI toolkit (ncbi.nlm.nih.gov:/toolkit) +*/ + +#ifdef NCBI + +#include +#include +#include + +/* NCBI toolkit :include: must be on lib path */ +#include +#include + +#define UREADASN +#include "ureadseq.h" + +#pragma segment ureadasn + +/* this stuff is hacked up from tofasta.c of ncbitools */ +#define kBaseAny 0 +#define kBaseNucleic 1 +#define kBaseAmino 2 + +typedef struct tofasta { + Boolean idonly; + short *seqnum; + short whichSeq; + char **seq, **seqid; + long *seqlen; +} FastaDat, PNTR FastaPtr; + + +void BioseqRawToRaw(BioseqPtr bsp, Boolean idonly, + short whichSeq, short *seqnum, + char **seq, char **seqid, long *seqlen) +{ + SeqPortPtr spp; + SeqIdPtr bestid; + Uint1 repr, code, residue; + CharPtr tmp, title; + long outlen, outmax; + char localid[256], *sp; + + /* !!! this may be called several times for a single sequence + because SeqEntryExplore looks for parts and joins them... + assume seq, seqid, seqlen may contain data (or NULL) + */ + if (bsp == NULL) return; + repr = Bioseq_repr(bsp); + if (!(repr == Seq_repr_raw || repr == Seq_repr_const)) return; + + (*seqnum)++; + if (!(whichSeq == *seqnum || whichSeq == 0)) return; + + bestid = SeqIdFindBest(bsp->id, (Uint1) 0); + title = BioseqGetTitle(bsp); + if (idonly) { + sprintf(localid, " %d) ", *seqnum); + tmp= localid + strlen(localid)-1; + } + else { + strcpy(localid," "); + tmp= localid; + } + tmp = SeqIdPrint(bestid, tmp, PRINTID_FASTA_SHORT); + tmp = StringMove(tmp, " "); + StringNCpy(tmp, title, 200); +/* fprintf(stderr,"BioseqRawToRaw: localid='%s'\n",localid); */ + + /* < seqid is fixed storage */ + /* strcpy( *seqid, localid); */ + /* < seqid is variable sized */ + outmax= strlen(localid) + 3; + if (*seqid==NULL) { + *seqid= (char*) malloc(outmax); + if (*seqid==NULL) return; + strcpy(*seqid, localid); + } + else { + outmax += strlen(*seqid) + 2; + *seqid= (char*) realloc( *seqid, outmax); + if (*seqid==NULL) return; + if (!idonly) strcat(*seqid, "; "); + strcat(*seqid, localid); + } + + if (idonly) { + strcat(*seqid,"\n"); + return; + } + + if (ISA_na(bsp->mol)) code = Seq_code_iupacna; + else code = Seq_code_iupacaa; + spp = SeqPortNew(bsp, 0, -1, 0, code); + SeqPortSeek(spp, 0, SEEK_SET); + + sp= *seq; + if (sp==NULL) { /* this is always true now !? */ + outlen= 0; + outmax= 500; + sp= (char*) malloc(outmax); + } + else { + outlen= strlen(sp); + outmax= outlen + 500; + sp= (char*) realloc( sp, outmax); + } + if (sp==NULL) return; + + while ((residue = SeqPortGetResidue(spp)) != SEQPORT_EOF) { + if (outlen>=outmax) { + outmax= outlen + 500; + sp= (char*) realloc(sp, outmax); + if (sp==NULL) return; + } + sp[outlen++] = residue; + } + sp= (char*) realloc(sp, outlen+1); + if (sp!=NULL) sp[outlen]= '\0'; + *seq= sp; + *seqlen= outlen; + SeqPortFree(spp); + return; +} + + +static void SeqEntryRawseq(SeqEntryPtr sep, Pointer data, Int4 index, Int2 indent) +{ + FastaPtr tfa; + BioseqPtr bsp; + + if (!IS_Bioseq(sep)) return; + bsp = (BioseqPtr)sep->data.ptrvalue; + tfa = (FastaPtr) data; + BioseqRawToRaw(bsp, tfa->idonly, tfa->whichSeq, tfa->seqnum, + tfa->seq, tfa->seqid, tfa->seqlen); +} + +void SeqEntryToRaw(SeqEntryPtr sep, Boolean idonly, short whichSeq, short *seqnum, + char **seq, char **seqid, long *seqlen) +{ + FastaDat tfa; + + if (sep == NULL) return; + tfa.idonly= idonly; + tfa.seqnum= seqnum; + tfa.whichSeq= whichSeq; + tfa.seq = seq; + tfa.seqid = seqid; + tfa.seqlen= seqlen; + SeqEntryExplore(sep, (Pointer)&tfa, SeqEntryRawseq); +} + + + + +char *listASNSeqs(const char *filename, const long skiplines, + const short format, /* note: this is kASNseqentry or kASNseqset */ + short *nseq, short *error ) +{ + AsnIoPtr aip = NULL; + SeqEntryPtr the_set; + AsnTypePtr atp, atp2; + AsnModulePtr amp; + Boolean inIsBinary= FALSE; /* damn, why can't asn routines test this? */ + char *seq = NULL; + char *seqid = NULL, stemp[256]; + long seqlen; + int i, count; + + *nseq= 0; + *error= 0; + + /* asn dictionary setups */ +/*fprintf(stderr,"listASNSeqs: SeqEntryLoad\n");*/ + if (! SeqEntryLoad()) goto errxit; /* sequence alphabets (and sequence parse trees) */ + amp = AsnAllModPtr(); /* get pointer to all loaded ASN.1 modules */ + if (amp == NULL) goto errxit; + atp = AsnFind("Bioseq-set"); /* get the initial type pointers */ + if (atp == NULL) goto errxit; + atp2 = AsnFind("Bioseq-set.seq-set.E"); + if (atp2 == NULL) goto errxit; + +/*fprintf(stderr,"listASNSeqs: AsnIoOpen\n");*/ + /* open the ASN.1 input file in the right mode */ + /* !!!! THIS FAILS when filename has MAC PATH (& other paths?) (:folder:filename) */ + if ((aip = AsnIoOpen(filename, inIsBinary?"rb":"r")) == NULL) goto errxit; + for (i=0; ifp); /* this may mess up asn routines... */ + + if (! ErrSetLog ("stderr")) goto errxit; + else ErrSetOpts(ERR_CONTINUE, ERR_LOG_ON); /*?? log errors instead of die */ + + if (format == kASNseqentry) { /* read one Seq-entry */ +/*fprintf(stderr,"listASNSeqs: SeqEntryAsnRead\n");*/ + the_set = SeqEntryAsnRead(aip, NULL); + SeqEntryToRaw(the_set, true, 0, nseq, &seq, &seqid, &seqlen); + if (seq) free(seq); seq= NULL; + SeqEntryFree(the_set); + } + else { /* read Seq-entry's from a Bioseq-set */ + count = 0; +/*fprintf(stderr,"listASNSeqs: AsnReadId\n");*/ + while ((atp = AsnReadId(aip, amp, atp)) != NULL) { + if (atp == atp2) { /* top level Seq-entry */ + the_set = SeqEntryAsnRead(aip, atp); + SeqEntryToRaw(the_set, true, 0, nseq, &seq, &seqid, &seqlen); + SeqEntryFree(the_set); + if (seq) free(seq); seq= NULL; + } + else + AsnReadVal(aip, atp, NULL); + count++; + } + } + + AsnIoClose(aip); + *error= 0; + return seqid; + +errxit: + AsnIoClose(aip); + if (seqid) free(seqid); + *error= eASNerr; + return NULL; +} + + +char *readASNSeq(const short whichEntry, const char *filename, + const long skiplines, + const short format, /* note: this is kASNseqentry or kASNseqset */ + long *seqlen, short *nseq, + short *error, char **seqid ) +{ + AsnIoPtr aip = NULL; + SeqEntryPtr the_set; + AsnTypePtr atp, atp2; + AsnModulePtr amp; + Boolean inIsBinary= FALSE; /* damn, why can't asn routines test this? */ + char *seq, stemp[200]; + int i, count; + + *seqlen= 0; + *nseq= 0; + *error= 0; + seq= NULL; + +/*fprintf(stderr,"readASNseq: SeqEntryLoad\n");*/ + /* asn dictionary setups */ + if (! SeqEntryLoad()) goto errxit; /* sequence alphabets (and sequence parse trees) */ + amp = AsnAllModPtr(); /* get pointer to all loaded ASN.1 modules */ + if (amp == NULL) goto errxit; + atp = AsnFind("Bioseq-set"); /* get the initial type pointers */ + if (atp == NULL) goto errxit; + atp2 = AsnFind("Bioseq-set.seq-set.E"); + if (atp2 == NULL) goto errxit; + + /* open the ASN.1 input file in the right mode */ +/*fprintf(stderr,"readASNseq: AsnIoOpen(%s)\n", filename);*/ + if ((aip = AsnIoOpen(filename, inIsBinary?"rb":"r")) == NULL) goto errxit; + for (i=0; ifp); /* this may mess up asn routines... */ + + if (! ErrSetLog ("stderr")) goto errxit; + else ErrSetOpts(ERR_CONTINUE, ERR_LOG_ON); /*?? log errors instead of die */ + + seq= NULL; + if (format == kASNseqentry) { /* read one Seq-entry */ +/*fprintf(stderr,"readASNseq: SeqEntryAsnRead\n");*/ + the_set = SeqEntryAsnRead(aip, NULL); + SeqEntryToRaw(the_set, false, whichEntry, nseq, &seq, seqid, seqlen); + SeqEntryFree(the_set); + goto goodexit; + } + + else { /* read Seq-entry's from a Bioseq-set */ + count = 0; +/*fprintf(stderr,"readASNseq: AsnReadId\n");*/ + while ((atp = AsnReadId(aip, amp, atp)) != NULL) { + if (atp == atp2) { /* top level Seq-entry */ + the_set = SeqEntryAsnRead(aip, atp); + SeqEntryToRaw(the_set, false, whichEntry, nseq, &seq, seqid, seqlen); + SeqEntryFree(the_set); + if (*nseq >= whichEntry) goto goodexit; + } + else + AsnReadVal(aip, atp, NULL); + count++; + } + } + +goodexit: + AsnIoClose(aip); + *error= 0; + return seq; + +errxit: + AsnIoClose(aip); + *error= eASNerr; + if (seq) free(seq); + return NULL; +} + + +#endif /*NCBI*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.c new file mode 100755 index 00000000..f2410b97 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.c @@ -0,0 +1,1880 @@ +/* File: ureadseq.c + * + * Reads and writes nucleic/protein sequence in various + * formats. Data files may have multiple sequences. + * + * Copyright 1990 by d.g.gilbert + * biology dept., indiana university, bloomington, in 47405 + * e-mail: gilbertd@bio.indiana.edu + * + * This program may be freely copied and used by anyone. + * Developers are encourged to incorporate parts in their + * programs, rather than devise their own private sequence + * format. + * + * This should compile and run with any ANSI C compiler. + * + */ + + +#include +#include +#include + +#define UREADSEQ_G +#include "ureadseq.h" + +#pragma segment ureadseq + + +int Strcasecmp(const char *a, const char *b) /* from Nlm_StrICmp */ +{ + int diff, done; + if (a == b) return 0; + done = 0; + while (! done) { + diff = to_upper(*a) - to_upper(*b); + if (diff) return diff; + if (*a == '\0') done = 1; + else { a++; b++; } + } + return 0; +} + +int Strncasecmp(const char *a, const char *b, long maxn) /* from Nlm_StrNICmp */ +{ + int diff, done; + if (a == b) return 0; + done = 0; + while (! done) { + diff = to_upper(*a) - to_upper(*b); + if (diff) return diff; + if (*a == '\0') done = 1; + else { + a++; b++; maxn--; + if (! maxn) done = 1; + } + } + return 0; +} + + + + + +#ifndef Local +# define Local static /* local functions */ +#endif + +#define kStartLength 50000 + +const char *aminos = "ABCDEFGHIKLMNPQRSTVWXYZ*"; +const char *primenuc = "ACGTU"; +const char *protonly = "EFIPQZ"; + +const char kNocountsymbols[5] = "_.-?"; +const char stdsymbols[6] = "_.-*?"; +const char allsymbols[32] = "_.-*?<>{}[]()!@#$%^&=+;:'/|`~\"\\"; +static const char *seqsymbols = allsymbols; + +const char nummask[11] = "0123456789"; +const char nonummask[11] = "~!@#$%^&*("; + +/* + use general form of isseqchar -- all chars + symbols. + no formats except nbrf (?) use symbols in data area as + anything other than sequence chars. +*/ + + + + /* Local variables for readSeq: */ +struct ReadSeqVars { + short choice, err, nseq; + long seqlen, maxseq, seqlencount; + short topnseq; + long topseqlen; + const char *fname; + char *seq, *seqid, matchchar; + boolean allDone, done, filestart, addit; + FILE *f; + long linestart; + char s[256], *sp; + + int (*isseqchar)(); + /* int (*isseqchar)(int c); << sgi cc hates (int c) */ +}; + + + +int isSeqChar(int c) +{ + return (isalpha(c) || strchr(seqsymbols,c)); +} + +int isSeqNumChar(int c) +{ + return (isalnum(c) || strchr(seqsymbols,c)); +} + + +int isAnyChar(int c) +{ + return isascii(c); /* wrap in case isascii is macro */ +} + +Local void readline(FILE *f, char *s, long *linestart) +{ + char *cp; + + *linestart= ftell(f); + if (NULL == fgets(s, 256, f)) + *s = 0; + else { + cp = strchr(s, '\n'); + if (cp != NULL) *cp = 0; + } +} + +Local void getline(struct ReadSeqVars *V) +{ + readline(V->f, V->s, &V->linestart); +} + +Local void ungetline(struct ReadSeqVars *V) +{ + fseek(V->f, V->linestart, 0); +} + + +Local void addseq(char *s, struct ReadSeqVars *V) +{ + char *ptr; + + if (V->addit) while (*s != 0) { + if ((V->isseqchar)(*s)) { + if (V->seqlen >= V->maxseq) { + V->maxseq += kStartLength; + ptr = (char*) realloc(V->seq, V->maxseq+1); + if (ptr==NULL) { + V->err = eMemFull; + return; + } + else V->seq = ptr; + } + V->seq[(V->seqlen)++] = *s; + } + s++; + } +} + +Local void countseq(char *s, struct ReadSeqVars *V) + /* this must count all valid seq chars, for some formats (paup-sequential) even + if we are skipping seq... */ +{ + while (*s != 0) { + if ((V->isseqchar)(*s)) { + (V->seqlencount)++; + } + s++; + } +} + + +Local void addinfo(char *s, struct ReadSeqVars *V) +{ + char s2[256], *si; + boolean saveadd; + + si = s2; + while (*s == ' ') s++; + sprintf(si, " %d) %s\n", V->nseq, s); + + saveadd = V->addit; + V->addit = true; + V->isseqchar = isAnyChar; + addseq( si, V); + V->addit = saveadd; + V->isseqchar = isSeqChar; +} + + + + +Local void readLoop(short margin, boolean addfirst, + boolean (*endTest)(boolean *addend, boolean *ungetend, struct ReadSeqVars *V), + struct ReadSeqVars *V) +{ + boolean addend = false; + boolean ungetend = false; + + V->nseq++; + if (V->choice == kListSequences) V->addit = false; + else V->addit = (V->nseq == V->choice); + if (V->addit) V->seqlen = 0; + + if (addfirst) addseq(V->s, V); + do { + getline(V); + V->done = feof(V->f); + V->done |= (*endTest)( &addend, &ungetend, V); + if (V->addit && (addend || !V->done) && (strlen(V->s) > margin)) { + addseq( (V->s)+margin, V); + } + } while (!V->done); + + if (V->choice == kListSequences) addinfo(V->seqid, V); + else { + V->allDone = (V->nseq >= V->choice); + if (V->allDone && ungetend) ungetline(V); + } +} + + + +Local boolean endIG( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = true; /* 1 or 2 occur in line w/ bases */ + *ungetend= false; + return((strchr(V->s,'1')!=NULL) || (strchr(V->s,'2')!=NULL)); +} + +Local void readIG(struct ReadSeqVars *V) +{ +/* 18Aug92: new IG format -- ^L between sequences in place of ";" */ + char *si; + + while (!V->allDone) { + do { + getline(V); + for (si= V->s; *si != 0 && *si < ' '; si++) *si= ' '; /* drop controls */ + if (*si == 0) *V->s= 0; /* chop line to empty */ + } while (! (feof(V->f) || ((*V->s != 0) && (*V->s != ';') ) )); + if (feof(V->f)) + V->allDone = true; + else { + strcpy(V->seqid, V->s); + readLoop(0, false, endIG, V); + } + } +} + + + +Local boolean endStrider( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= false; + return (strstr( V->s, "//") != NULL); +} + +Local void readStrider(struct ReadSeqVars *V) +{ /* ? only 1 seq/file ? */ + + while (!V->allDone) { + getline(V); + if (strstr(V->s,"; DNA sequence ") == V->s) + strcpy(V->seqid, (V->s)+16); + else + strcpy(V->seqid, (V->s)+1); + while ((!feof(V->f)) && (*V->s == ';')) { + getline(V); + } + if (feof(V->f)) V->allDone = true; + else readLoop(0, true, endStrider, V); + } +} + + +Local boolean endPIR( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"ENTRY") == V->s); + return ((strstr(V->s,"///") != NULL) || *ungetend); +} + +Local void readPIR(struct ReadSeqVars *V) +{ /*PIR -- many seqs/file */ + + while (!V->allDone) { + while (! (feof(V->f) || strstr(V->s,"ENTRY") || strstr(V->s,"SEQUENCE")) ) + getline(V); + strcpy(V->seqid, (V->s)+16); + while (! (feof(V->f) || strstr(V->s,"SEQUENCE") == V->s)) + getline(V); + readLoop(0, false, endPIR, V); + + if (!V->allDone) { + while (! (feof(V->f) || ((*V->s != 0) + && (strstr( V->s,"ENTRY") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + +Local boolean endGB( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"LOCUS") == V->s); + return ((strstr(V->s,"//") != NULL) || *ungetend); +} + +Local void readGenBank(struct ReadSeqVars *V) +{ /*GenBank -- many seqs/file */ + + while (!V->allDone) { + strcpy(V->seqid, (V->s)+12); + while (! (feof(V->f) || strstr(V->s,"ORIGIN") == V->s)) + getline(V); + readLoop(0, false, endGB, V); + + if (!V->allDone) { + while (! (feof(V->f) || ((*V->s != 0) + && (strstr( V->s,"LOCUS") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + +Local boolean endNBRF( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + char *a; + + if ((a = strchr(V->s, '*')) != NULL) { /* end of 1st seq */ + /* "*" can be valid base symbol, drop it here */ + *a = 0; + *addend = true; + *ungetend= false; + return(true); + } + else if (*V->s == '>') { /* start of next seq */ + *addend = false; + *ungetend= true; + return(true); + } + else + return(false); +} + +Local void readNBRF(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+4); + getline(V); /*skip title-junk line*/ + readLoop(0, false, endNBRF, V); + if (!V->allDone) { + while (!(feof(V->f) || (*V->s != 0 && *V->s == '>'))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endPearson( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= true; + return(*V->s == '>'); +} + +Local void readPearson(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+1); + readLoop(0, false, endPearson, V); + if (!V->allDone) { + while (!(feof(V->f) || ((*V->s != 0) && (*V->s == '>')))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endEMBL( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"ID ") == V->s); + return ((strstr(V->s,"//") != NULL) || *ungetend); +} + +Local void readEMBL(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+5); + do { + getline(V); + } while (!(feof(V->f) | (strstr(V->s,"SQ ") == V->s))); + + readLoop(0, false, endEMBL, V); + if (!V->allDone) { + while (!(feof(V->f) | + ((*V->s != '\0') & (strstr(V->s,"ID ") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endZuker( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= true; + return( *V->s == '(' ); +} + +Local void readZuker(struct ReadSeqVars *V) +{ + /*! 1st string is Zuker's Fortran format */ + + while (!V->allDone) { + getline(V); /*s == "seqLen seqid string..."*/ + strcpy(V->seqid, (V->s)+6); + readLoop(0, false, endZuker, V); + if (!V->allDone) { + while (!(feof(V->f) | + ((*V->s != '\0') & (*V->s == '(')))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endFitch( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + /* this is a somewhat shaky end, + 1st char of line is non-blank for seq. title + */ + *addend = false; + *ungetend= true; + return( *V->s != ' ' ); +} + +Local void readFitch(struct ReadSeqVars *V) +{ + boolean first; + + first = true; + while (!V->allDone) { + if (!first) strcpy(V->seqid, V->s); + readLoop(0, first, endFitch, V); + if (feof(V->f)) V->allDone = true; + first = false; + } +} + + +Local void readPlain(struct ReadSeqVars *V) +{ + V->nseq++; + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + addseq(V->seqid, V); /*from above..*/ + if (V->fname!=NULL) sprintf(V->seqid, "%s [Unknown form]", V->fname); + else sprintf(V->seqid, " [Unknown form]"); + do { + addseq(V->s, V); + V->done = feof(V->f); + getline(V); + } while (!V->done); + if (V->choice == kListSequences) addinfo(V->seqid, V); + V->allDone = true; +} + + +Local void readUWGCG(struct ReadSeqVars *V) +{ +/* +10nov91: Reading GCG files casued duplication of last line when + EOF followed that line !!! + fix: getline now sets *V->s = 0 +*/ + char *si; + + V->nseq++; + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + strcpy(V->seqid, V->s); + /*writeseq: " %s Length: %d (today) Check: %d ..\n" */ + /*drop above or ".." from id*/ + if (si = strstr(V->seqid," Length: ")) *si = 0; + else if (si = strstr(V->seqid,"..")) *si = 0; + do { + V->done = feof(V->f); + getline(V); + if (!V->done) addseq((V->s), V); + } while (!V->done); + if (V->choice == kListSequences) addinfo(V->seqid, V); + V->allDone = true; +} + + +Local void readOlsen(struct ReadSeqVars *V) +{ /* G. Olsen /print output from multiple sequence editor */ + + char *si, *sj, *sk, *sm, sid[40], snum[20]; + boolean indata = false; + int snumlen; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + rewind(V->f); V->nseq= 0; + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + if ( (si= strstr(V->s, sid)) + /* && (strstr(V->s, snum) == si - snumlen - 1) ) { */ + && (sm= strstr(V->s, snum)) && (sm < si - snumlen) ) { + + /* Spaces are valid alignment data !! */ +/* 17Oct91: Error, the left margin is 21 not 22! */ +/* dropped some nucs up to now -- my example file was right shifted ! */ +/* variable right id margin, drop id-2 spaces at end */ +/* + VMS CC COMPILER (VAXC031) mess up: + -- Index of 21 is chopping 1st nuc on VMS systems Only! + Byte-for-byte same ame rnasep.olsen sequence file ! +*/ + + /* si = (V->s)+21; < was this before VMS CC wasted my time */ + si += 10; /* use strstr index plus offset to outfox VMS CC bug */ + + if (sk = strstr(si, sid)) *(sk-2) = 0; + for (sk = si; *sk != 0; sk++) { + if (*sk == ' ') *sk = '.'; + /* 18aug92: !! some olsen masks are NUMBERS !! which addseq eats */ + else if (isdigit(*sk)) *sk= nonummask[*sk - '0']; + } + + addseq(si, V); + } + } + + else if (sk = strstr(V->s, "): ")) { /* seq info header line */ + /* 18aug92: correct for diff seqs w/ same name -- use number, e.g. */ + /* 3 (Agr.tume): agrobacterium.prna 18-JUN-1987 16:12 */ + /* 328 (Agr.tume): agrobacterium.prna XYZ 19-DEC-1992 */ + (V->nseq)++; + si = 1 + strchr(V->s,'('); + *sk = ' '; + if (V->choice == kListSequences) addinfo( si, V); + else if (V->nseq == V->choice) { + strcpy(V->seqid, si); + sj = strchr(V->seqid, ':'); + while (*(--sj) == ' ') ; + while (--sj != V->seqid) { if (*sj == ' ') *sj = '_'; } + + *sk = 0; + while (*(--sk) == ' ') *sk = 0; + strcpy(sid, si); + + si= V->s; + while ((*si <= ' ') && (*si != 0)) si++; + snumlen=0; + while (si[snumlen] > ' ' && snumlen<20) + { snum[snumlen]= si[snumlen]; snumlen++; } + snum[snumlen]= 0; + } + + } + + else if (strstr(V->s,"identity: Data:")) { + indata = true; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readOlsen*/ + + +Local void readMSF(struct ReadSeqVars *V) +{ /* gcg's MSF, mult. sequence format, interleaved ! */ + + char *si, *sj, sid[128]; + boolean indata = false; + int atseq= 0, iline= 0; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + rewind(V->f); V->nseq= 0; + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /*somename ...gpvedai .......t.. aaigr..vad tvgtgptnse aipaltaaet */ + /* E gvenae.kgv tentna.tad fvaqpvylpe .nqt...... kv.affynrs */ + + si= V->s; + skipwhitespace(si); + /* for (sj= si; isalnum(*sj); sj++) ; bug -- cdelwiche uses "-", "_" and others in names*/ + for (sj= si; *sj > ' '; sj++) ; + *sj= 0; + if ( *si ) { + if ( (0==strcmp(si, sid)) ) { + addseq(sj+1, V); + } + iline++; + } + } + + else if (NULL != (si = strstr(V->s, "Name: "))) { /* seq info header line */ + /* Name: somename Len: 100 Check: 7009 Weight: 1.00 */ + + (V->nseq)++; + si += 6; + if (V->choice == kListSequences) addinfo( si, V); + else if (V->nseq == V->choice) { + strcpy(V->seqid, si); + si = V->seqid; + skipwhitespace(si); + /* for (sj= si; isalnum(*sj); sj++) ; -- bug */ + for (sj= si; *sj > ' '; sj++) ; + *sj= 0; + strcpy(sid, si); + } + } + + else if ( strstr(V->s,"//") /*== V->s*/ ) { + indata = true; + iline= 0; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + + V->allDone = true; +} /*readMSF*/ + + + +Local void readPAUPinterleaved(struct ReadSeqVars *V) +{ /* PAUP mult. sequence format, interleaved or sequential! */ + + char *si, *sj, *send, sid[40], sid1[40], saveseq[255]; + boolean first = true, indata = false, domatch; + int atseq= 0, iline= 0, ifmc, saveseqlen=0; + +#define fixmatchchar(s) { \ + for (ifmc=0; ifmcmatchchar) s[ifmc]= saveseq[ifmc]; } + + V->addit = (V->choice > 0); + V->seqlencount = 0; + if (V->addit) V->seqlen = 0; + /* rewind(V->f); V->nseq= 0; << do in caller !*/ + indata= true; /* call here after we find "matrix" */ + domatch= (V->matchchar > 0); + + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /* [ 1 1 1 ]*/ + /* human aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* chimp ................a.t. .c.................a ..........*/ + /* !! need to correct for V->matchchar */ + si= V->s; + skipwhitespace(si); + if (strchr(si,';')) indata= false; + + if (isalnum(*si)) { + /* valid data line starts w/ a left-justified seq name in columns [0..8] */ + if (first) { + (V->nseq)++; + if (V->nseq >= V->topnseq) first= false; + for (sj = si; isalnum(*sj); sj++) ; + send= sj; + skipwhitespace(sj); + if (V->choice == kListSequences) { + *send= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + if (domatch) { + if (V->nseq == 1) { strcpy( saveseq, sj); saveseqlen= strlen(saveseq); } + else fixmatchchar( sj); + } + addseq(sj, V); + *send= 0; + strcpy(V->seqid, si); + strcpy(sid, si); + if (V->nseq == 1) strcpy(sid1, sid); + } + } + + else if ( (strstr(si, sid) == si) ){ + while (isalnum(*si)) si++; + skipwhitespace(si); + if (domatch) { + if (V->nseq == 1) { strcpy( saveseq, si); saveseqlen= strlen(saveseq); } + else fixmatchchar( si); + } + addseq(si, V); + } + + else if (domatch && (strstr(si, sid1) == si)) { + strcpy( saveseq, si); + saveseqlen= strlen(saveseq); + } + + iline++; + } + } + + else if ( strstr(V->s,"matrix") ) { + indata = true; + iline= 0; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readPAUPinterleaved*/ + + + +Local void readPAUPsequential(struct ReadSeqVars *V) +{ /* PAUP mult. sequence format, interleaved or sequential! */ + char *si, *sj; + boolean atname = true, indata = false; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + V->seqlencount = 0; + /* rewind(V->f); V->nseq= 0; << do in caller !*/ + indata= true; /* call here after we find "matrix" */ + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /* [ 1 1 1 ]*/ + /* human aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* chimp ................a.t. .c.................a ..........*/ + /* ................a.t. .c.................a ..........*/ + + si= V->s; + skipwhitespace(si); + if (strchr(si,';')) indata= false; + if (isalnum(*si)) { + /* valid data line starts w/ a left-justified seq name in columns [0..8] */ + if (atname) { + (V->nseq)++; + V->seqlencount = 0; + atname= false; + sj= si+1; + while (isalnum(*sj)) sj++; + if (V->choice == kListSequences) { + /* !! we must count bases to know when topseqlen is reached ! */ + countseq(sj, V); + if (V->seqlencount >= V->topseqlen) atname= true; + *sj= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + addseq(sj, V); + V->seqlencount= V->seqlen; + if (V->seqlencount >= V->topseqlen) atname= true; + *sj= 0; + strcpy(V->seqid, si); + } + else { + countseq(sj, V); + if (V->seqlencount >= V->topseqlen) atname= true; + } + } + + else if (V->nseq == V->choice) { + addseq(V->s, V); + V->seqlencount= V->seqlen; + if (V->seqlencount >= V->topseqlen) atname= true; + } + else { + countseq(V->s, V); + if (V->seqlencount >= V->topseqlen) atname= true; + } + } + } + + else if ( strstr(V->s,"matrix") ) { + indata = true; + atname= true; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readPAUPsequential*/ + + +Local void readPhylipInterleaved(struct ReadSeqVars *V) +{ + char *si, *sj; + boolean first = true; + int iline= 0; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + V->seqlencount = 0; + /* sscanf( V->s, "%d%d", &V->topnseq, &V->topseqlen); << topnseq == 0 !!! bad scan !! */ + si= V->s; + skipwhitespace(si); + V->topnseq= atoi(si); + while (isdigit(*si)) si++; + skipwhitespace(si); + V->topseqlen= atol(si); + /* fprintf(stderr,"Phylip-ileaf: topnseq=%d topseqlen=%d\n",V->topnseq, V->topseqlen); */ + + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + si= V->s; + skipwhitespace(si); + if (*si != 0) { + + if (first) { /* collect seq names + seq, as fprintf(outf,"%-10s ",seqname); */ + (V->nseq)++; + if (V->nseq >= V->topnseq) first= false; + sj= V->s+10; /* past name, start of data */ + if (V->choice == kListSequences) { + *sj= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + addseq(sj, V); + *sj= 0; + strcpy(V->seqid, si); + } + } + else if ( iline % V->nseq == V->choice -1 ) { + addseq(si, V); + } + iline++; + } + } while (!V->done); + + V->allDone = true; +} /*readPhylipInterleaved*/ + + + +Local boolean endPhylipSequential( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= false; + countseq( V->s, V); + return V->seqlencount >= V->topseqlen; +} + +Local void readPhylipSequential(struct ReadSeqVars *V) +{ + short i; + char *si; + /* sscanf( V->s, "%d%d", &V->topnseq, &V->topseqlen); < ? bad sscan ? */ + si= V->s; + skipwhitespace(si); + V->topnseq= atoi(si); + while (isdigit(*si)) si++; + skipwhitespace(si); + V->topseqlen= atol(si); + getline(V); + while (!V->allDone) { + V->seqlencount= 0; + strncpy(V->seqid, (V->s), 10); + V->seqid[10]= 0; + for (i=0; i<10 && V->s[i]; i++) V->s[i]= ' '; + readLoop(0, true, endPhylipSequential, V); + if (feof(V->f)) V->allDone = true; + } +} + + + + +Local void readSeqMain( + struct ReadSeqVars *V, + const long skiplines_, + const short format_) +{ +#define tolowerstr(s) { long Itlwr, Ntlwr= strlen(s); \ + for (Itlwr=0; Itlwrlinestart= 0; + V->matchchar= 0; + if (V->f == NULL) + V->err = eFileNotFound; + else { + + for (l = skiplines_; l > 0; l--) getline( V); + + do { + getline( V); + for (l= strlen(V->s); (l > 0) && (V->s[l] == ' '); l--) ; + } while ((l == 0) && !feof(V->f)); + + if (feof(V->f)) V->err = eNoData; + + else switch (format_) { + case kPlain : readPlain(V); break; + case kIG : readIG(V); break; + case kStrider: readStrider(V); break; + case kGenBank: readGenBank(V); break; + case kPIR : readPIR(V); break; + case kNBRF : readNBRF(V); break; + case kPearson: readPearson(V); break; + case kEMBL : readEMBL(V); break; + case kZuker : readZuker(V); break; + case kOlsen : readOlsen(V); break; + case kMSF : readMSF(V); break; + + case kPAUP : { + boolean done= false; + boolean interleaved= false; + char *cp; + /* rewind(V->f); V->nseq= 0; ?? assume it is at top ?? skiplines ... */ + while (!done) { + getline( V); + tolowerstr( V->s); + if (strstr( V->s, "matrix")) done= true; + if (strstr( V->s, "interleav")) interleaved= true; + if (NULL != (cp=strstr( V->s, "ntax=")) ) V->topnseq= atoi(cp+5); + if (NULL != (cp=strstr( V->s, "nchar=")) ) V->topseqlen= atoi(cp+6); + if (NULL != (cp=strstr( V->s, "matchchar=")) ) { + cp += 10; + if (*cp=='\'') cp++; + else if (*cp=='"') cp++; + V->matchchar= *cp; + } + } + if (interleaved) readPAUPinterleaved(V); + else readPAUPsequential(V); + } + break; + + /* kPhylip: ! can't determine in middle of file which type it is...*/ + /* test for interleave or sequential and use Phylip4(ileave) or Phylip2 */ + case kPhylip2: + readPhylipSequential(V); + break; + case kPhylip4: /* == kPhylip3 */ + readPhylipInterleaved(V); + break; + + default: + V->err = eUnknownFormat; + break; + + case kFitch : + strcpy(V->seqid, V->s); getline(V); + readFitch(V); + break; + + case kGCG: + do { + gotuw = (strstr(V->s,"..") != NULL); + if (gotuw) readUWGCG(V); + getline(V); + } while (!(feof(V->f) || V->allDone)); + break; + } + } + + V->filestart= false; + V->seq[V->seqlen] = 0; /* stick a string terminator on it */ +} + + +char *readSeqFp( + const short whichEntry_, /* index to sequence in file */ + FILE *fp_, /* pointer to open seq file */ + const long skiplines_, + const short format_, /* sequence file format */ + long *seqlen_, /* return seq size */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_, /* return error */ + char *seqid_) /* return seq name/info */ +{ + struct ReadSeqVars V; + + if (format_ < kMinFormat || format_ > kMaxFormat) { + *error_ = eUnknownFormat; + *seqlen_ = 0; + return NULL; + } + + V.choice = whichEntry_; + V.fname = NULL; /* don't know */ + V.seq = (char*) calloc(1, kStartLength+1); + V.maxseq = kStartLength; + V.seqlen = 0; + V.seqid = seqid_; + + V.f = fp_; + V.filestart= (ftell( fp_) == 0); + /* !! in sequential read, must remove current seq position from choice/whichEntry_ counter !! ... */ + if (V.filestart) V.nseq = 0; + else V.nseq= *nseq_; /* track where we are in file...*/ + + *V.seqid = '\0'; + V.err = 0; + V.nseq = 0; + V.isseqchar = isSeqChar; + if (V.choice == kListSequences) ; /* leave as is */ + else if (V.choice <= 0) V.choice = 1; /* default ?? */ + V.addit = (V.choice > 0); + V.allDone = false; + + readSeqMain(&V, skiplines_, format_); + + *error_ = V.err; + *seqlen_ = V.seqlen; + *nseq_ = V.nseq; + return V.seq; +} + +char *readSeq( + const short whichEntry_, /* index to sequence in file */ + const char *filename_, /* file name */ + const long skiplines_, + const short format_, /* sequence file format */ + long *seqlen_, /* return seq size */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_, /* return error */ + char *seqid_) /* return seq name/info */ +{ + struct ReadSeqVars V; + + if (format_ < kMinFormat || format_ > kMaxFormat) { + *error_ = eUnknownFormat; + *seqlen_ = 0; + return NULL; + } + + V.choice = whichEntry_; + V.fname = filename_; /* don't need to copy string, just ptr to it */ + V.seq = (char*) calloc(1, kStartLength+1); + V.maxseq = kStartLength; + V.seqlen = 0; + V.seqid = seqid_; + + V.f = NULL; + *V.seqid = '\0'; + V.err = 0; + V.nseq = 0; + V.isseqchar = isSeqChar; + if (V.choice == kListSequences) ; /* leave as is */ + else if (V.choice <= 0) V.choice = 1; /* default ?? */ + V.addit = (V.choice > 0); + V.allDone = false; + + V.f = fopen(V.fname, "r"); + V.filestart= true; + + readSeqMain(&V, skiplines_, format_); + + if (V.f != NULL) fclose(V.f); + *error_ = V.err; + *seqlen_ = V.seqlen; + *nseq_ = V.nseq; + return V.seq; +} + + + + + +char *listSeqs( + const char *filename_, /* file name */ + const long skiplines_, + const short format_, /* sequence file format */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_) /* return error */ +{ + char seqid[256]; + long seqlen; + + return readSeq( kListSequences, filename_, skiplines_, format_, + &seqlen, nseq_, error_, seqid); +} + + + + +short seqFileFormat( /* return sequence format number, see ureadseq.h */ + const char *filename, + long *skiplines, /* return #lines to skip any junk like mail header */ + short *error) /* return any error value or 0 */ +{ + FILE *fseq; + short format; + + fseq = fopen(filename, "r"); + format= seqFileFormatFp( fseq, skiplines, error); + if (fseq!=NULL) fclose(fseq); + return format; +} + +short seqFileFormatFp( + FILE *fseq, + long *skiplines, /* return #lines to skip any junk like mail header */ + short *error) /* return any error value or 0 */ +{ + boolean foundDNA= false, foundIG= false, foundStrider= false, + foundGB= false, foundPIR= false, foundEMBL= false, foundNBRF= false, + foundPearson= false, foundFitch= false, foundPhylip= false, foundZuker= false, + gotolsen= false, gotpaup = false, gotasn1 = false, gotuw= false, gotMSF= false, + isfitch= false, isphylip= false, done= false; + short format= kUnknown; + int nlines= 0, k, splen= 0, otherlines= 0, aminolines= 0, dnalines= 0; + char sp[256]; + long linestart=0; + int maxlines2check=500; + +#define ReadOneLine(sp) \ + { done |= (feof(fseq)); \ + readline( fseq, sp, &linestart); \ + if (!done) { splen = strlen(sp); ++nlines; } } + + *skiplines = 0; + *error = 0; + if (fseq == NULL) { *error = eFileNotFound; return kNoformat; } + + while ( !done ) { + ReadOneLine(sp); + + /* check for mailer head & skip past if found */ + if (nlines < 4 && !done) { + if ((strstr(sp,"From ") == sp) || (strstr(sp,"Received:") == sp)) { + do { + /* skip all lines until find one blank line */ + ReadOneLine(sp); + if (!done) for (k=0; (k') { + if (sp[3] == ';') foundNBRF= true; + else foundPearson= true; + } + + else if (strstr(sp,"ID ") == sp) + foundEMBL= true; + else if (strstr(sp,"SQ ") == sp) + foundEMBL= true; + + else if (*sp == '(') + foundZuker= true; + + else { + if (nlines - *skiplines == 1) { + int ispp= 0, ilen= 0; + sscanf( sp, "%d%d", &ispp, &ilen); + if (ispp > 0 && ilen > 0) isphylip= true; + } + else if (isphylip && nlines - *skiplines == 2) { + int tseq; + tseq= getseqtype(sp+10, strlen(sp+10)); + if ( isalpha(*sp) /* 1st letter in 2nd line must be of a name */ + && (tseq != kOtherSeq)) /* sequence section must be okay */ + foundPhylip= true; + } + + for (k=0, isfitch= true; isfitch & (k < splen); k++) { + if (k % 4 == 0) isfitch &= (sp[k] == ' '); + else isfitch &= (sp[k] != ' '); + } + if (isfitch & (splen > 20)) foundFitch= true; + + /* kRNA && kDNA are fairly certain...*/ + switch (getseqtype( sp, splen)) { + case kOtherSeq: otherlines++; break; + case kAmino : if (splen>20) aminolines++; break; + case kDNA : + case kRNA : if (splen>20) dnalines++; break; + case kNucleic : break; /* not much info ? */ + } + + } + + /* pretty certain */ + if (gotolsen) { + format= kOlsen; + done= true; + } + else if (gotMSF) { + format= kMSF; + done= true; + } + else if (gotasn1) { + /* !! we need to look further and return kASNseqentry | kASNseqset */ + /* + seqentry key is Seq-entry ::= + seqset key is Bioseq-set ::= + ?? can't read these yet w/ ncbi tools ?? + Seq-submit ::= + Bioseq ::= << fails both bioseq-seq and seq-entry parsers ! + */ + if (strstr(sp,"Bioseq-set")) format= kASNseqset; + else if (strstr(sp,"Seq-entry")) format= kASNseqentry; + else format= kASN1; /* other form, we can't yet read... */ + done= true; + } + else if (gotpaup) { + format= kPAUP; + done= true; + } + + else if (gotuw) { + if (foundIG) format= kIG; /* a TOIG file from GCG for certain */ + else format= kGCG; + done= true; + } + + else if ((dnalines > 1) || done || (nlines > maxlines2check)) { + /* decide on most likely format */ + /* multichar idents: */ + if (foundStrider) format= kStrider; + else if (foundGB) format= kGenBank; + else if (foundPIR) format= kPIR; + else if (foundEMBL) format= kEMBL; + else if (foundNBRF) format= kNBRF; + /* single char idents: */ + else if (foundIG) format= kIG; + else if (foundPearson) format= kPearson; + else if (foundZuker) format= kZuker; + /* digit ident: */ + else if (foundPhylip) format= kPhylip; + /* spacing ident: */ + else if (foundFitch) format= kFitch; + /* no format chars: */ + else if (otherlines > 0) format= kUnknown; + else if (dnalines > 1) format= kPlain; + else if (aminolines > 1) format= kPlain; + else format= kUnknown; + + done= true; + } + + /* need this for possible long header in olsen format */ + else if (strstr(sp,"): ") != NULL) + maxlines2check++; + } + + if (format == kPhylip) { + /* check for interleaved or sequential -- really messy */ + int tname, tseq; + long i, j, nspp= 0, nlen= 0, ilen, leaf= 0, seq= 0; + char *ps; + + rewind(fseq); + for (i=0; i < *skiplines; i++) ReadOneLine(sp); + nlines= 0; + ReadOneLine(sp); + sscanf( sp, "%d%d", &nspp, &nlen); + ReadOneLine(sp); /* 1st seq line */ + for (ps= sp+10, ilen=0; *ps!=0; ps++) if (isprint(*ps)) ilen++; + + for (i= 1; i=9) seq += 10; /* pretty certain not ileaf */ + else { + if (tseq != tname) leaf++; else seq++; + if (tname == kDNA || tname == kRNA) seq++; else leaf++; + } + + if (ilen <= nlen && j<9) { + if (tname == kOtherSeq) leaf += 10; + else if (tname == kAmino || tname == kDNA || tname == kRNA) seq++; else leaf++; + } + else if (ilen > nlen) { + ilen= 0; + } + } + for ( nspp *= 2 ; i nlen) { + if (j>9) leaf += 10; /* must be a name here for sequent */ + else if (tname == kOtherSeq) seq += 10; + ilen= 0; + } + } + + if (leaf > seq) format= kPhylip4; + else format= kPhylip2; + } + + return(format); +#undef ReadOneLine +} /* SeqFileFormat */ + + + + +unsigned long GCGchecksum( const char *seq, const long seqlen, unsigned long *checktotal) +/* GCGchecksum */ +{ + register long i, check = 0, count = 0; + + for (i = 0; i < seqlen; i++) { + count++; + check += count * to_upper(seq[i]); + if (count == 57) count = 0; + } + check %= 10000; + *checktotal += check; + *checktotal %= 10000; + return check; +} + +/* Table of CRC-32's of all single byte values (made by makecrc.c of ZIP source) */ +const unsigned long crctab[] = { + 0x00000000L, 0x77073096L, 0xee0e612cL, 0x990951baL, 0x076dc419L, + 0x706af48fL, 0xe963a535L, 0x9e6495a3L, 0x0edb8832L, 0x79dcb8a4L, + 0xe0d5e91eL, 0x97d2d988L, 0x09b64c2bL, 0x7eb17cbdL, 0xe7b82d07L, + 0x90bf1d91L, 0x1db71064L, 0x6ab020f2L, 0xf3b97148L, 0x84be41deL, + 0x1adad47dL, 0x6ddde4ebL, 0xf4d4b551L, 0x83d385c7L, 0x136c9856L, + 0x646ba8c0L, 0xfd62f97aL, 0x8a65c9ecL, 0x14015c4fL, 0x63066cd9L, + 0xfa0f3d63L, 0x8d080df5L, 0x3b6e20c8L, 0x4c69105eL, 0xd56041e4L, + 0xa2677172L, 0x3c03e4d1L, 0x4b04d447L, 0xd20d85fdL, 0xa50ab56bL, + 0x35b5a8faL, 0x42b2986cL, 0xdbbbc9d6L, 0xacbcf940L, 0x32d86ce3L, + 0x45df5c75L, 0xdcd60dcfL, 0xabd13d59L, 0x26d930acL, 0x51de003aL, + 0xc8d75180L, 0xbfd06116L, 0x21b4f4b5L, 0x56b3c423L, 0xcfba9599L, + 0xb8bda50fL, 0x2802b89eL, 0x5f058808L, 0xc60cd9b2L, 0xb10be924L, + 0x2f6f7c87L, 0x58684c11L, 0xc1611dabL, 0xb6662d3dL, 0x76dc4190L, + 0x01db7106L, 0x98d220bcL, 0xefd5102aL, 0x71b18589L, 0x06b6b51fL, + 0x9fbfe4a5L, 0xe8b8d433L, 0x7807c9a2L, 0x0f00f934L, 0x9609a88eL, + 0xe10e9818L, 0x7f6a0dbbL, 0x086d3d2dL, 0x91646c97L, 0xe6635c01L, + 0x6b6b51f4L, 0x1c6c6162L, 0x856530d8L, 0xf262004eL, 0x6c0695edL, + 0x1b01a57bL, 0x8208f4c1L, 0xf50fc457L, 0x65b0d9c6L, 0x12b7e950L, + 0x8bbeb8eaL, 0xfcb9887cL, 0x62dd1ddfL, 0x15da2d49L, 0x8cd37cf3L, + 0xfbd44c65L, 0x4db26158L, 0x3ab551ceL, 0xa3bc0074L, 0xd4bb30e2L, + 0x4adfa541L, 0x3dd895d7L, 0xa4d1c46dL, 0xd3d6f4fbL, 0x4369e96aL, + 0x346ed9fcL, 0xad678846L, 0xda60b8d0L, 0x44042d73L, 0x33031de5L, + 0xaa0a4c5fL, 0xdd0d7cc9L, 0x5005713cL, 0x270241aaL, 0xbe0b1010L, + 0xc90c2086L, 0x5768b525L, 0x206f85b3L, 0xb966d409L, 0xce61e49fL, + 0x5edef90eL, 0x29d9c998L, 0xb0d09822L, 0xc7d7a8b4L, 0x59b33d17L, + 0x2eb40d81L, 0xb7bd5c3bL, 0xc0ba6cadL, 0xedb88320L, 0x9abfb3b6L, + 0x03b6e20cL, 0x74b1d29aL, 0xead54739L, 0x9dd277afL, 0x04db2615L, + 0x73dc1683L, 0xe3630b12L, 0x94643b84L, 0x0d6d6a3eL, 0x7a6a5aa8L, + 0xe40ecf0bL, 0x9309ff9dL, 0x0a00ae27L, 0x7d079eb1L, 0xf00f9344L, + 0x8708a3d2L, 0x1e01f268L, 0x6906c2feL, 0xf762575dL, 0x806567cbL, + 0x196c3671L, 0x6e6b06e7L, 0xfed41b76L, 0x89d32be0L, 0x10da7a5aL, + 0x67dd4accL, 0xf9b9df6fL, 0x8ebeeff9L, 0x17b7be43L, 0x60b08ed5L, + 0xd6d6a3e8L, 0xa1d1937eL, 0x38d8c2c4L, 0x4fdff252L, 0xd1bb67f1L, + 0xa6bc5767L, 0x3fb506ddL, 0x48b2364bL, 0xd80d2bdaL, 0xaf0a1b4cL, + 0x36034af6L, 0x41047a60L, 0xdf60efc3L, 0xa867df55L, 0x316e8eefL, + 0x4669be79L, 0xcb61b38cL, 0xbc66831aL, 0x256fd2a0L, 0x5268e236L, + 0xcc0c7795L, 0xbb0b4703L, 0x220216b9L, 0x5505262fL, 0xc5ba3bbeL, + 0xb2bd0b28L, 0x2bb45a92L, 0x5cb36a04L, 0xc2d7ffa7L, 0xb5d0cf31L, + 0x2cd99e8bL, 0x5bdeae1dL, 0x9b64c2b0L, 0xec63f226L, 0x756aa39cL, + 0x026d930aL, 0x9c0906a9L, 0xeb0e363fL, 0x72076785L, 0x05005713L, + 0x95bf4a82L, 0xe2b87a14L, 0x7bb12baeL, 0x0cb61b38L, 0x92d28e9bL, + 0xe5d5be0dL, 0x7cdcefb7L, 0x0bdbdf21L, 0x86d3d2d4L, 0xf1d4e242L, + 0x68ddb3f8L, 0x1fda836eL, 0x81be16cdL, 0xf6b9265bL, 0x6fb077e1L, + 0x18b74777L, 0x88085ae6L, 0xff0f6a70L, 0x66063bcaL, 0x11010b5cL, + 0x8f659effL, 0xf862ae69L, 0x616bffd3L, 0x166ccf45L, 0xa00ae278L, + 0xd70dd2eeL, 0x4e048354L, 0x3903b3c2L, 0xa7672661L, 0xd06016f7L, + 0x4969474dL, 0x3e6e77dbL, 0xaed16a4aL, 0xd9d65adcL, 0x40df0b66L, + 0x37d83bf0L, 0xa9bcae53L, 0xdebb9ec5L, 0x47b2cf7fL, 0x30b5ffe9L, + 0xbdbdf21cL, 0xcabac28aL, 0x53b39330L, 0x24b4a3a6L, 0xbad03605L, + 0xcdd70693L, 0x54de5729L, 0x23d967bfL, 0xb3667a2eL, 0xc4614ab8L, + 0x5d681b02L, 0x2a6f2b94L, 0xb40bbe37L, 0xc30c8ea1L, 0x5a05df1bL, + 0x2d02ef8dL +}; + +unsigned long CRC32checksum(const char *seq, const long seqlen, unsigned long *checktotal) +/*CRC32checksum: modified from CRC-32 algorithm found in ZIP compression source */ +{ + register unsigned long c = 0xffffffffL; + register long n = seqlen; + + while (n--) { + c = crctab[((int)c ^ (to_upper(*seq))) & 0xff] ^ (c >> 8); + seq++; /* fixed aug'98 finally */ + } + c= c ^ 0xffffffffL; + *checktotal += c; + return c; +} + + + + +short getseqtype( const char *seq, const long seqlen) +{ /* return sequence kind: kDNA, kRNA, kProtein, kOtherSeq, ??? */ + char c; + short i, maxtest; + short na = 0, aa = 0, po = 0, nt = 0, nu = 0, ns = 0, no = 0; + + maxtest = min(300, seqlen); + for (i = 0; i < maxtest; i++) { + c = to_upper(seq[i]); + if (strchr(protonly, c)) po++; + else if (strchr(primenuc,c)) { + na++; + if (c == 'T') nt++; + else if (c == 'U') nu++; + } + else if (strchr(aminos,c)) aa++; + else if (strchr(seqsymbols,c)) ns++; + else if (isalpha(c)) no++; + } + + if ((no > 0) || (po+aa+na == 0)) return kOtherSeq; + /* ?? test for probability of kOtherSeq ?, e.g., + else if (po+aa+na / maxtest < 0.70) return kOtherSeq; + */ + else if (po > 0) return kAmino; + else if (aa == 0) { + if (nu > nt) return kRNA; + else return kDNA; + } + else if (na > aa) return kNucleic; + else return kAmino; +} /* getseqtype */ + + +char* compressSeq( const char gapc, const char *seq, const long seqlen, long *newlen) +{ + register char *a, *b; + register long i; + char *newseq; + + *newlen= 0; + if (!seq) return NULL; + newseq = (char*) malloc(seqlen+1); + if (!newseq) return NULL; + for (a= (char*)seq, b=newseq, i=0; *a!=0; a++) + if (*a != gapc) { + *b++= *a; + i++; + } + *b= '\0'; + newseq = (char*) realloc(newseq, i+1); + *newlen= i; + return newseq; +} + + + +/*** +char *rtfhead = "{\\rtf1\\defformat\\mac\\deff2 \ +{\\fonttbl\ + {\\f1\\fmodern Courier;}{\\f2\\fmodern Monaco;}\ + {\\f3\\fswiss Helvetica;}{\\f4\\fswiss Geneva;}\ + {\\f5\\froman Times;}{\\f6\\froman Palatino;}\ + {\\f7\\froman New Century Schlbk;}{\\f8\\ftech Symbol;}}\ +{\\stylesheet\ + {\\s1 \\f5\\fs20 \\sbasedon0\\snext1 name;}\ + {\\s2 \\f3\\fs20 \\sbasedon0\\snext2 num;}\ + {\\s3 \\f1\\f21 \\sbasedon0\\snext3 seq;}}"; + +char *rtftail = "}"; +****/ + +short writeSeq(FILE *outf, const char *seq, const long seqlen, + const short outform, const char *seqid) +/* dump sequence to standard output */ +{ + const short kSpaceAll = -9; +#define kMaxseqwidth 250 + + boolean baseonlynum= false; /* nocountsymbols -- only count true bases, not "-" */ + short numline = 0; /* only true if we are writing seq number line (for interleave) */ + boolean numright = false, numleft = false; + boolean nameright = false, nameleft = false; + short namewidth = 8, numwidth = 8; + short spacer = 0, width = 50, tab = 0; + /* new parameters: width, spacer, those above... */ + + short linesout = 0, seqtype = kNucleic; + long i, j, l, l1, ibase; + char idword[31], endstr[10]; + char seqnamestore[128], *seqname = seqnamestore; + char s[kMaxseqwidth], *cp; + char nameform[10], numform[10], nocountsymbols[10]; + unsigned long checksum = 0, checktotal = 0; + + gPretty.atseq++; + skipwhitespace(seqid); + l = min(128, strlen(seqid)); + strncpy( seqnamestore, seqid, l); + seqname[l] = 0; + + sscanf( seqname, "%30s", idword); + sprintf(numform, "%d", seqlen); + numwidth= strlen(numform)+1; + nameform[0]= '\0'; + + if (strstr(seqname,"checksum") != NULL) { + cp = strstr(seqname,"bases"); + if (cp!=NULL) { + for ( ; (cp!=seqname) && (*cp!=','); cp--) ; + if (cp!=seqname) *cp=0; + } + } + + strcpy( endstr,""); + l1 = 0; + + if (outform == kGCG || outform == kMSF) + checksum = GCGchecksum(seq, seqlen, &checktotal); + else + checksum = seqchecksum(seq, seqlen, &checktotal); + + switch (outform) { + + case kPlain: + case kUnknown: /* no header, just sequence */ + strcpy(endstr,"\n"); /* end w/ extra blank line */ + break; + + case kOlsen: /* Olsen seq. editor takes plain nucs OR Genbank */ + case kGenBank: + fprintf(outf,"LOCUS %s %d bp\n", idword, seqlen); + fprintf(outf,"DEFINITION %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf,"ORIGIN \n"); + spacer = 11; + numleft = true; + numwidth = 8; /* dgg. 1Feb93, patch for GDE fail to read short numwidth */ + strcpy(endstr, "\n//"); + linesout += 4; + break; + + case kPIR: + /* somewhat like genbank... \\\*/ + /* fprintf(outf,"\\\\\\\n"); << only at top of file, not each entry... */ + fprintf(outf,"ENTRY %s \n", idword); + fprintf(outf,"TITLE %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf,"SEQUENCE \n"); + numwidth = 7; + width= 30; + spacer = kSpaceAll; + numleft = true; + strcpy(endstr, "\n///"); + /* run a top number line for PIR */ + for (j=0; jP1;%s\n", idword); + else + fprintf(outf,">DL;%s\n", idword); + fprintf(outf,"%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + spacer = 11; + strcpy(endstr,"*\n"); + linesout += 3; + break; + + case kEMBL: + fprintf(outf,"ID %s\n", idword); + /* fprintf(outf,"AC %s\n", accnum); */ + fprintf(outf,"DE %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + fprintf(outf,"SQ %d BP\n", seqlen); + strcpy(endstr, "\n//"); /* 11Oct90: bug fix*/ + tab = 4; /** added 31jan91 */ + spacer = 11; /** added 31jan91 */ + width = 60; + linesout += 4; + break; + + case kGCG: + fprintf(outf,"%s\n", seqname); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf," %s Length: %d (today) Check: %d ..\n", idword, seqlen, checksum); + spacer = 11; + numleft = true; + strcpy(endstr, "\n"); /* this is insurance to help prevent misreads at eof */ + linesout += 3; + break; + + case kStrider: /* ?? map ?*/ + fprintf(outf,"; ### from DNA Strider ;-)\n"); + fprintf(outf,"; DNA sequence %s, %d bases, %X checksum.\n;\n", seqname, seqlen, checksum); + strcpy(endstr, "\n//"); + linesout += 3; + break; + + case kFitch: + fprintf(outf,"%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + spacer = 4; + width = 60; + linesout += 1; + break; + + case kPhylip2: + case kPhylip4: + /* this is version 3.2/3.4 -- simplest way to write + version 3.3 is to write as version 3.2, then + re-read file and interleave the species lines */ + if (strlen(idword)>10) idword[10] = 0; + fprintf(outf,"%-10s ",idword); + l1 = -1; + tab = 12; + spacer = 11; + break; + + case kASN1: + seqtype= getseqtype(seq, seqlen); + switch (seqtype) { + case kDNA : cp= "dna"; break; + case kRNA : cp= "rna"; break; + case kNucleic : cp= "na"; break; + case kAmino : cp= "aa"; break; + case kOtherSeq: cp= "not-set"; break; + } + fprintf(outf," seq {\n"); + fprintf(outf," id { local id %d },\n", gPretty.atseq); + fprintf(outf," descr { title \"%s\" },\n", seqid); + fprintf(outf," inst {\n"); + fprintf(outf," repr raw, mol %s, length %d, topology linear,\n", cp, seqlen); + fprintf(outf," seq-data\n"); + if (seqtype == kAmino) + fprintf(outf," iupacaa \""); + else + fprintf(outf," iupacna \""); + l1 = 17; + spacer = 0; + width = 78; + tab = 0; + strcpy(endstr,"\"\n } } ,"); + linesout += 7; + break; + + case kPAUP: + nameleft= true; + namewidth = 9; + spacer = 21; + width = 100; + tab = 0; /* 1; */ + /* strcpy(endstr,";\nend;"); << this is end of all seqs.. */ + /* do a header comment line for paup */ + fprintf(outf,"[Name: %-16s Len:%6d Check: %8X]\n", idword, seqlen, checksum); + linesout += 1; + break; + + case kPretty: + numline= gPretty.numline; + baseonlynum= gPretty.baseonlynum; + namewidth = gPretty.namewidth; + numright = gPretty.numright; + numleft = gPretty.numleft; + nameright = gPretty.nameright; + nameleft = gPretty.nameleft; + spacer = gPretty.spacer + 1; + width = gPretty.seqwidth; + tab = gPretty.tab; + /* also add rtf formatting w/ font, size, style */ + if (gPretty.nametop) { + fprintf(outf,"Name: %-16s Len:%6d Check: %8X\n", idword, seqlen, checksum); + linesout++; + } + break; + + case kMSF: + fprintf(outf," Name: %-16s Len:%6d Check: %5d Weight: 1.00\n", + idword, seqlen, checksum); + linesout++; + nameleft= true; + namewidth= 15; /* need MAX namewidth here... */ + sprintf(nameform, "%%+%ds ",namewidth); + spacer = 11; + width = 50; + tab = 0; /* 1; */ + break; + + case kIG: + fprintf(outf,";%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + fprintf(outf,"%s\n", idword); + strcpy(endstr,"1"); /* == linear dna */ + linesout += 2; + break; + + case kZuker: /* don't attempt Zuker's ftn format */ + case kPearson: + fprintf(outf,">%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + linesout += 1; + break; + + default: + case kVienna: /* Vienna RNA Package Format */ + fprintf(outf,"> %s [%d bases, %X]\n", seqname, seqlen, checksum); + fprintf(outf,"%s\n", seq); + return 2; + } + + if (*nameform==0) sprintf(nameform, "%%%d.%ds ",namewidth,namewidth); + if (numline) sprintf(numform, "%%%ds ",numwidth); + else sprintf(numform, "%%%dd ",numwidth); + strcpy( nocountsymbols, kNocountsymbols); + if (baseonlynum) { + if (strchr(nocountsymbols,gPretty.gapchar)==NULL) { + strcat(nocountsymbols," "); + nocountsymbols[strlen(nocountsymbols)-1]= gPretty.gapchar; + } + if (gPretty.domatch && (cp=strchr(nocountsymbols,gPretty.matchchar))!=NULL) { + *cp= ' '; + } + } + + if (numline) { + *idword= 0; + } + + width = min(width,kMaxseqwidth); + for (i=0, l=0, ibase = 1; i < seqlen; ) { + + if (l1 < 0) l1 = 0; + else if (l1 == 0) { + if (nameleft) fprintf(outf, nameform, idword); + if (numleft) { if (numline) fprintf(outf, numform, ""); + else fprintf(outf, numform, ibase);} + for (j=0; j +#include +#include + +#define UREADSEQ_G +#include "ureadseq.h" + +#pragma segment ureadseq + + +int Strcasecmp(const char *a, const char *b) /* from Nlm_StrICmp */ +{ + int diff, done; + if (a == b) return 0; + done = 0; + while (! done) { + diff = to_upper(*a) - to_upper(*b); + if (diff) return diff; + if (*a == '\0') done = 1; + else { a++; b++; } + } + return 0; +} + +int Strncasecmp(const char *a, const char *b, long maxn) /* from Nlm_StrNICmp */ +{ + int diff, done; + if (a == b) return 0; + done = 0; + while (! done) { + diff = to_upper(*a) - to_upper(*b); + if (diff) return diff; + if (*a == '\0') done = 1; + else { + a++; b++; maxn--; + if (! maxn) done = 1; + } + } + return 0; +} + + + + + +#ifndef Local +# define Local static /* local functions */ +#endif + +#define kStartLength 500 + +const char *aminos = "ABCDEFGHIKLMNPQRSTVWXYZ*"; +const char *primenuc = "ACGTU"; +const char *protonly = "EFIPQZ"; + +const char kNocountsymbols[5] = "_.-?"; +const char stdsymbols[6] = "_.-*?"; +const char allsymbols[32] = "_.-*?<>{}[]()!@#$%^&=+;:'/|`~\"\\"; +static const char *seqsymbols = allsymbols; + +const char nummask[11] = "0123456789"; +const char nonummask[11] = "~!@#$%^&*("; + +/* + use general form of isseqchar -- all chars + symbols. + no formats except nbrf (?) use symbols in data area as + anything other than sequence chars. +*/ + + + + /* Local variables for readSeq: */ +struct ReadSeqVars { + short choice, err, nseq; + long seqlen, maxseq, seqlencount; + short topnseq; + long topseqlen; + const char *fname; + char *seq, *seqid, matchchar; + boolean allDone, done, filestart, addit; + FILE *f; + long linestart; + char s[256], *sp; + + int (*isseqchar)(); + /* int (*isseqchar)(int c); << sgi cc hates (int c) */ +}; + + + +int isSeqChar(int c) +{ + return (isalpha(c) || strchr(seqsymbols,c)); +} + +int isSeqNumChar(int c) +{ + return (isalnum(c) || strchr(seqsymbols,c)); +} + + +int isAnyChar(int c) +{ + return isascii(c); /* wrap in case isascii is macro */ +} + +Local void readline(FILE *f, char *s, long *linestart) +{ + char *cp; + + *linestart= ftell(f); + if (NULL == fgets(s, 256, f)) + *s = 0; + else { + cp = strchr(s, '\n'); + if (cp != NULL) *cp = 0; + } +} + +Local void getline(struct ReadSeqVars *V) +{ + readline(V->f, V->s, &V->linestart); +} + +Local void ungetline(struct ReadSeqVars *V) +{ + fseek(V->f, V->linestart, 0); +} + + +Local void addseq(char *s, struct ReadSeqVars *V) +{ + char *ptr; + + if (V->addit) while (*s != 0) { + if ((V->isseqchar)(*s)) { + if (V->seqlen >= V->maxseq) { + V->maxseq += kStartLength; + ptr = (char*) realloc(V->seq, V->maxseq+1); + if (ptr==NULL) { + V->err = eMemFull; + return; + } + else V->seq = ptr; + } + V->seq[(V->seqlen)++] = *s; + } + s++; + } +} + +Local void countseq(char *s, struct ReadSeqVars *V) + /* this must count all valid seq chars, for some formats (paup-sequential) even + if we are skipping seq... */ +{ + while (*s != 0) { + if ((V->isseqchar)(*s)) { + (V->seqlencount)++; + } + s++; + } +} + + +Local void addinfo(char *s, struct ReadSeqVars *V) +{ + char s2[256], *si; + boolean saveadd; + + si = s2; + while (*s == ' ') s++; + sprintf(si, " %d) %s\n", V->nseq, s); + + saveadd = V->addit; + V->addit = true; + V->isseqchar = isAnyChar; + addseq( si, V); + V->addit = saveadd; + V->isseqchar = isSeqChar; +} + + + + +Local void readLoop(short margin, boolean addfirst, + boolean (*endTest)(boolean *addend, boolean *ungetend, struct ReadSeqVars *V), + struct ReadSeqVars *V) +{ + boolean addend = false; + boolean ungetend = false; + + V->nseq++; + if (V->choice == kListSequences) V->addit = false; + else V->addit = (V->nseq == V->choice); + if (V->addit) V->seqlen = 0; + + if (addfirst) addseq(V->s, V); + do { + getline(V); + V->done = feof(V->f); + V->done |= (*endTest)( &addend, &ungetend, V); + if (V->addit && (addend || !V->done) && (strlen(V->s) > margin)) { + addseq( (V->s)+margin, V); + } + } while (!V->done); + + if (V->choice == kListSequences) addinfo(V->seqid, V); + else { + V->allDone = (V->nseq >= V->choice); + if (V->allDone && ungetend) ungetline(V); + } +} + + + +Local boolean endIG( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = true; /* 1 or 2 occur in line w/ bases */ + *ungetend= false; + return((strchr(V->s,'1')!=NULL) || (strchr(V->s,'2')!=NULL)); +} + +Local void readIG(struct ReadSeqVars *V) +{ +/* 18Aug92: new IG format -- ^L between sequences in place of ";" */ + char *si; + + while (!V->allDone) { + do { + getline(V); + for (si= V->s; *si != 0 && *si < ' '; si++) *si= ' '; /* drop controls */ + if (*si == 0) *V->s= 0; /* chop line to empty */ + } while (! (feof(V->f) || ((*V->s != 0) && (*V->s != ';') ) )); + if (feof(V->f)) + V->allDone = true; + else { + strcpy(V->seqid, V->s); + readLoop(0, false, endIG, V); + } + } +} + + + +Local boolean endStrider( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= false; + return (strstr( V->s, "//") != NULL); +} + +Local void readStrider(struct ReadSeqVars *V) +{ /* ? only 1 seq/file ? */ + + while (!V->allDone) { + getline(V); + if (strstr(V->s,"; DNA sequence ") == V->s) + strcpy(V->seqid, (V->s)+16); + else + strcpy(V->seqid, (V->s)+1); + while ((!feof(V->f)) && (*V->s == ';')) { + getline(V); + } + if (feof(V->f)) V->allDone = true; + else readLoop(0, true, endStrider, V); + } +} + + +Local boolean endPIR( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"ENTRY") == V->s); + return ((strstr(V->s,"///") != NULL) || *ungetend); +} + +Local void readPIR(struct ReadSeqVars *V) +{ /*PIR -- many seqs/file */ + + while (!V->allDone) { + while (! (feof(V->f) || strstr(V->s,"ENTRY") || strstr(V->s,"SEQUENCE")) ) + getline(V); + strcpy(V->seqid, (V->s)+16); + while (! (feof(V->f) || strstr(V->s,"SEQUENCE") == V->s)) + getline(V); + readLoop(0, false, endPIR, V); + + if (!V->allDone) { + while (! (feof(V->f) || ((*V->s != 0) + && (strstr( V->s,"ENTRY") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + +Local boolean endGB( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"LOCUS") == V->s); + return ((strstr(V->s,"//") != NULL) || *ungetend); +} + +Local void readGenBank(struct ReadSeqVars *V) +{ /*GenBank -- many seqs/file */ + + while (!V->allDone) { + strcpy(V->seqid, (V->s)+12); + while (! (feof(V->f) || strstr(V->s,"ORIGIN") == V->s)) + getline(V); + readLoop(0, false, endGB, V); + + if (!V->allDone) { + while (! (feof(V->f) || ((*V->s != 0) + && (strstr( V->s,"LOCUS") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + +Local boolean endNBRF( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + char *a; + + if ((a = strchr(V->s, '*')) != NULL) { /* end of 1st seq */ + /* "*" can be valid base symbol, drop it here */ + *a = 0; + *addend = true; + *ungetend= false; + return(true); + } + else if (*V->s == '>') { /* start of next seq */ + *addend = false; + *ungetend= true; + return(true); + } + else + return(false); +} + +Local void readNBRF(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+4); + getline(V); /*skip title-junk line*/ + readLoop(0, false, endNBRF, V); + if (!V->allDone) { + while (!(feof(V->f) || (*V->s != 0 && *V->s == '>'))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endPearson( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= true; + return(*V->s == '>'); +} + +Local void readPearson(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+1); + readLoop(0, false, endPearson, V); + if (!V->allDone) { + while (!(feof(V->f) || ((*V->s != 0) && (*V->s == '>')))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endEMBL( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= (strstr(V->s,"ID ") == V->s); + return ((strstr(V->s,"//") != NULL) || *ungetend); +} + +Local void readEMBL(struct ReadSeqVars *V) +{ + while (!V->allDone) { + strcpy(V->seqid, (V->s)+5); + do { + getline(V); + } while (!(feof(V->f) | (strstr(V->s,"SQ ") == V->s))); + + readLoop(0, false, endEMBL, V); + if (!V->allDone) { + while (!(feof(V->f) | + ((*V->s != '\0') & (strstr(V->s,"ID ") == V->s)))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endZuker( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= true; + return( *V->s == '(' ); +} + +Local void readZuker(struct ReadSeqVars *V) +{ + /*! 1st string is Zuker's Fortran format */ + + while (!V->allDone) { + getline(V); /*s == "seqLen seqid string..."*/ + strcpy(V->seqid, (V->s)+6); + readLoop(0, false, endZuker, V); + if (!V->allDone) { + while (!(feof(V->f) | + ((*V->s != '\0') & (*V->s == '(')))) + getline(V); + } + if (feof(V->f)) V->allDone = true; + } +} + + + +Local boolean endFitch( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + /* this is a somewhat shaky end, + 1st char of line is non-blank for seq. title + */ + *addend = false; + *ungetend= true; + return( *V->s != ' ' ); +} + +Local void readFitch(struct ReadSeqVars *V) +{ + boolean first; + + first = true; + while (!V->allDone) { + if (!first) strcpy(V->seqid, V->s); + readLoop(0, first, endFitch, V); + if (feof(V->f)) V->allDone = true; + first = false; + } +} + + +Local void readPlain(struct ReadSeqVars *V) +{ + V->nseq++; + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + addseq(V->seqid, V); /*from above..*/ + if (V->fname!=NULL) sprintf(V->seqid, "%s [Unknown form]", V->fname); + else sprintf(V->seqid, " [Unknown form]"); + do { + addseq(V->s, V); + V->done = feof(V->f); + getline(V); + } while (!V->done); + if (V->choice == kListSequences) addinfo(V->seqid, V); + V->allDone = true; +} + + +Local void readUWGCG(struct ReadSeqVars *V) +{ +/* +10nov91: Reading GCG files casued duplication of last line when + EOF followed that line !!! + fix: getline now sets *V->s = 0 +*/ + char *si; + + V->nseq++; + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + strcpy(V->seqid, V->s); + /*writeseq: " %s Length: %d (today) Check: %d ..\n" */ + /*drop above or ".." from id*/ + if (si = strstr(V->seqid," Length: ")) *si = 0; + else if (si = strstr(V->seqid,"..")) *si = 0; + do { + V->done = feof(V->f); + getline(V); + if (!V->done) addseq((V->s), V); + } while (!V->done); + if (V->choice == kListSequences) addinfo(V->seqid, V); + V->allDone = true; +} + + +Local void readOlsen(struct ReadSeqVars *V) +{ /* G. Olsen /print output from multiple sequence editor */ + + char *si, *sj, *sk, *sm, sid[40], snum[20]; + boolean indata = false; + int snumlen; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + rewind(V->f); V->nseq= 0; + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + if ( (si= strstr(V->s, sid)) + /* && (strstr(V->s, snum) == si - snumlen - 1) ) { */ + && (sm= strstr(V->s, snum)) && (sm < si - snumlen) ) { + + /* Spaces are valid alignment data !! */ +/* 17Oct91: Error, the left margin is 21 not 22! */ +/* dropped some nucs up to now -- my example file was right shifted ! */ +/* variable right id margin, drop id-2 spaces at end */ +/* + VMS CC COMPILER (VAXC031) mess up: + -- Index of 21 is chopping 1st nuc on VMS systems Only! + Byte-for-byte same ame rnasep.olsen sequence file ! +*/ + + /* si = (V->s)+21; < was this before VMS CC wasted my time */ + si += 10; /* use strstr index plus offset to outfox VMS CC bug */ + + if (sk = strstr(si, sid)) *(sk-2) = 0; + for (sk = si; *sk != 0; sk++) { + if (*sk == ' ') *sk = '.'; + /* 18aug92: !! some olsen masks are NUMBERS !! which addseq eats */ + else if (isdigit(*sk)) *sk= nonummask[*sk - '0']; + } + + addseq(si, V); + } + } + + else if (sk = strstr(V->s, "): ")) { /* seq info header line */ + /* 18aug92: correct for diff seqs w/ same name -- use number, e.g. */ + /* 3 (Agr.tume): agrobacterium.prna 18-JUN-1987 16:12 */ + /* 328 (Agr.tume): agrobacterium.prna XYZ 19-DEC-1992 */ + (V->nseq)++; + si = 1 + strchr(V->s,'('); + *sk = ' '; + if (V->choice == kListSequences) addinfo( si, V); + else if (V->nseq == V->choice) { + strcpy(V->seqid, si); + sj = strchr(V->seqid, ':'); + while (*(--sj) == ' ') ; + while (--sj != V->seqid) { if (*sj == ' ') *sj = '_'; } + + *sk = 0; + while (*(--sk) == ' ') *sk = 0; + strcpy(sid, si); + + si= V->s; + while ((*si <= ' ') && (*si != 0)) si++; + snumlen=0; + while (si[snumlen] > ' ' && snumlen<20) + { snum[snumlen]= si[snumlen]; snumlen++; } + snum[snumlen]= 0; + } + + } + + else if (strstr(V->s,"identity: Data:")) { + indata = true; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readOlsen*/ + + +Local void readMSF(struct ReadSeqVars *V) +{ /* gcg's MSF, mult. sequence format, interleaved ! */ + + char *si, *sj, sid[128]; + boolean indata = false; + int atseq= 0, iline= 0; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + rewind(V->f); V->nseq= 0; + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /*somename ...gpvedai .......t.. aaigr..vad tvgtgptnse aipaltaaet */ + /* E gvenae.kgv tentna.tad fvaqpvylpe .nqt...... kv.affynrs */ + + si= V->s; + skipwhitespace(si); + /* for (sj= si; isalnum(*sj); sj++) ; bug -- cdelwiche uses "-", "_" and others in names*/ + for (sj= si; *sj > ' '; sj++) ; + *sj= 0; + if ( *si ) { + if ( (0==strcmp(si, sid)) ) { + addseq(sj+1, V); + } + iline++; + } + } + + else if (NULL != (si = strstr(V->s, "Name: "))) { /* seq info header line */ + /* Name: somename Len: 100 Check: 7009 Weight: 1.00 */ + + (V->nseq)++; + si += 6; + if (V->choice == kListSequences) addinfo( si, V); + else if (V->nseq == V->choice) { + strcpy(V->seqid, si); + si = V->seqid; + skipwhitespace(si); + /* for (sj= si; isalnum(*sj); sj++) ; -- bug */ + for (sj= si; *sj > ' '; sj++) ; + *sj= 0; + strcpy(sid, si); + } + } + + else if ( strstr(V->s,"//") /*== V->s*/ ) { + indata = true; + iline= 0; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + + V->allDone = true; +} /*readMSF*/ + + + +Local void readPAUPinterleaved(struct ReadSeqVars *V) +{ /* PAUP mult. sequence format, interleaved or sequential! */ + + char *si, *sj, *send, sid[40], sid1[40], saveseq[255]; + boolean first = true, indata = false, domatch; + int atseq= 0, iline= 0, ifmc, saveseqlen=0; + +#define fixmatchchar(s) { \ + for (ifmc=0; ifmcmatchchar) s[ifmc]= saveseq[ifmc]; } + + V->addit = (V->choice > 0); + V->seqlencount = 0; + if (V->addit) V->seqlen = 0; + /* rewind(V->f); V->nseq= 0; << do in caller !*/ + indata= true; /* call here after we find "matrix" */ + domatch= (V->matchchar > 0); + + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /* [ 1 1 1 ]*/ + /* human aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* chimp ................a.t. .c.................a ..........*/ + /* !! need to correct for V->matchchar */ + si= V->s; + skipwhitespace(si); + if (strchr(si,';')) indata= false; + + if (isalnum(*si)) { + /* valid data line starts w/ a left-justified seq name in columns [0..8] */ + if (first) { + (V->nseq)++; + if (V->nseq >= V->topnseq) first= false; + for (sj = si; isalnum(*sj); sj++) ; + send= sj; + skipwhitespace(sj); + if (V->choice == kListSequences) { + *send= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + if (domatch) { + if (V->nseq == 1) { strcpy( saveseq, sj); saveseqlen= strlen(saveseq); } + else fixmatchchar( sj); + } + addseq(sj, V); + *send= 0; + strcpy(V->seqid, si); + strcpy(sid, si); + if (V->nseq == 1) strcpy(sid1, sid); + } + } + + else if ( (strstr(si, sid) == si) ){ + while (isalnum(*si)) si++; + skipwhitespace(si); + if (domatch) { + if (V->nseq == 1) { strcpy( saveseq, si); saveseqlen= strlen(saveseq); } + else fixmatchchar( si); + } + addseq(si, V); + } + + else if (domatch && (strstr(si, sid1) == si)) { + strcpy( saveseq, si); + saveseqlen= strlen(saveseq); + } + + iline++; + } + } + + else if ( strstr(V->s,"matrix") ) { + indata = true; + iline= 0; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readPAUPinterleaved*/ + + + +Local void readPAUPsequential(struct ReadSeqVars *V) +{ /* PAUP mult. sequence format, interleaved or sequential! */ + char *si, *sj; + boolean atname = true, indata = false; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + V->seqlencount = 0; + /* rewind(V->f); V->nseq= 0; << do in caller !*/ + indata= true; /* call here after we find "matrix" */ + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + else if (indata) { + /* [ 1 1 1 ]*/ + /* human aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* aagcttcaccggcgcagtca ttctcataatcgcccacggR cttacatcct*/ + /* chimp ................a.t. .c.................a ..........*/ + /* ................a.t. .c.................a ..........*/ + + si= V->s; + skipwhitespace(si); + if (strchr(si,';')) indata= false; + if (isalnum(*si)) { + /* valid data line starts w/ a left-justified seq name in columns [0..8] */ + if (atname) { + (V->nseq)++; + V->seqlencount = 0; + atname= false; + sj= si+1; + while (isalnum(*sj)) sj++; + if (V->choice == kListSequences) { + /* !! we must count bases to know when topseqlen is reached ! */ + countseq(sj, V); + if (V->seqlencount >= V->topseqlen) atname= true; + *sj= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + addseq(sj, V); + V->seqlencount= V->seqlen; + if (V->seqlencount >= V->topseqlen) atname= true; + *sj= 0; + strcpy(V->seqid, si); + } + else { + countseq(sj, V); + if (V->seqlencount >= V->topseqlen) atname= true; + } + } + + else if (V->nseq == V->choice) { + addseq(V->s, V); + V->seqlencount= V->seqlen; + if (V->seqlencount >= V->topseqlen) atname= true; + } + else { + countseq(V->s, V); + if (V->seqlencount >= V->topseqlen) atname= true; + } + } + } + + else if ( strstr(V->s,"matrix") ) { + indata = true; + atname= true; + if (V->choice == kListSequences) V->done = true; + } + + } while (!V->done); + + V->allDone = true; +} /*readPAUPsequential*/ + + +Local void readPhylipInterleaved(struct ReadSeqVars *V) +{ + char *si, *sj; + boolean first = true; + int iline= 0; + + V->addit = (V->choice > 0); + if (V->addit) V->seqlen = 0; + V->seqlencount = 0; + /* sscanf( V->s, "%d%d", &V->topnseq, &V->topseqlen); << topnseq == 0 !!! bad scan !! */ + si= V->s; + skipwhitespace(si); + V->topnseq= atoi(si); + while (isdigit(*si)) si++; + skipwhitespace(si); + V->topseqlen= atol(si); + /* fprintf(stderr,"Phylip-ileaf: topnseq=%d topseqlen=%d\n",V->topnseq, V->topseqlen); */ + + do { + getline(V); + V->done = feof(V->f); + + if (V->done && !(*V->s)) break; + si= V->s; + skipwhitespace(si); + if (*si != 0) { + + if (first) { /* collect seq names + seq, as fprintf(outf,"%-10s ",seqname); */ + (V->nseq)++; + if (V->nseq >= V->topnseq) first= false; + sj= V->s+10; /* past name, start of data */ + if (V->choice == kListSequences) { + *sj= 0; + addinfo( si, V); + } + else if (V->nseq == V->choice) { + addseq(sj, V); + *sj= 0; + strcpy(V->seqid, si); + } + } + else if ( iline % V->nseq == V->choice -1 ) { + addseq(si, V); + } + iline++; + } + } while (!V->done); + + V->allDone = true; +} /*readPhylipInterleaved*/ + + + +Local boolean endPhylipSequential( boolean *addend, boolean *ungetend, struct ReadSeqVars *V) +{ + *addend = false; + *ungetend= false; + countseq( V->s, V); + return V->seqlencount >= V->topseqlen; +} + +Local void readPhylipSequential(struct ReadSeqVars *V) +{ + short i; + char *si; + /* sscanf( V->s, "%d%d", &V->topnseq, &V->topseqlen); < ? bad sscan ? */ + si= V->s; + skipwhitespace(si); + V->topnseq= atoi(si); + while (isdigit(*si)) si++; + skipwhitespace(si); + V->topseqlen= atol(si); + getline(V); + while (!V->allDone) { + V->seqlencount= 0; + strncpy(V->seqid, (V->s), 10); + V->seqid[10]= 0; + for (i=0; i<10 && V->s[i]; i++) V->s[i]= ' '; + readLoop(0, true, endPhylipSequential, V); + if (feof(V->f)) V->allDone = true; + } +} + + + + +Local void readSeqMain( + struct ReadSeqVars *V, + const long skiplines_, + const short format_) +{ +#define tolowerstr(s) { long Itlwr, Ntlwr= strlen(s); \ + for (Itlwr=0; Itlwrlinestart= 0; + V->matchchar= 0; + if (V->f == NULL) + V->err = eFileNotFound; + else { + + for (l = skiplines_; l > 0; l--) getline( V); + + do { + getline( V); + for (l= strlen(V->s); (l > 0) && (V->s[l] == ' '); l--) ; + } while ((l == 0) && !feof(V->f)); + + if (feof(V->f)) V->err = eNoData; + + else switch (format_) { + case kPlain : readPlain(V); break; + case kIG : readIG(V); break; + case kStrider: readStrider(V); break; + case kGenBank: readGenBank(V); break; + case kPIR : readPIR(V); break; + case kNBRF : readNBRF(V); break; + case kPearson: readPearson(V); break; + case kEMBL : readEMBL(V); break; + case kZuker : readZuker(V); break; + case kOlsen : readOlsen(V); break; + case kMSF : readMSF(V); break; + + case kPAUP : { + boolean done= false; + boolean interleaved= false; + char *cp; + /* rewind(V->f); V->nseq= 0; ?? assume it is at top ?? skiplines ... */ + while (!done) { + getline( V); + tolowerstr( V->s); + if (strstr( V->s, "matrix")) done= true; + if (strstr( V->s, "interleav")) interleaved= true; + if (NULL != (cp=strstr( V->s, "ntax=")) ) V->topnseq= atoi(cp+5); + if (NULL != (cp=strstr( V->s, "nchar=")) ) V->topseqlen= atoi(cp+6); + if (NULL != (cp=strstr( V->s, "matchchar=")) ) { + cp += 10; + if (*cp=='\'') cp++; + else if (*cp=='"') cp++; + V->matchchar= *cp; + } + } + if (interleaved) readPAUPinterleaved(V); + else readPAUPsequential(V); + } + break; + + /* kPhylip: ! can't determine in middle of file which type it is...*/ + /* test for interleave or sequential and use Phylip4(ileave) or Phylip2 */ + case kPhylip2: + readPhylipSequential(V); + break; + case kPhylip4: /* == kPhylip3 */ + readPhylipInterleaved(V); + break; + + default: + V->err = eUnknownFormat; + break; + + case kFitch : + strcpy(V->seqid, V->s); getline(V); + readFitch(V); + break; + + case kGCG: + do { + gotuw = (strstr(V->s,"..") != NULL); + if (gotuw) readUWGCG(V); + getline(V); + } while (!(feof(V->f) || V->allDone)); + break; + } + } + + V->filestart= false; + V->seq[V->seqlen] = 0; /* stick a string terminator on it */ +} + + +char *readSeqFp( + const short whichEntry_, /* index to sequence in file */ + FILE *fp_, /* pointer to open seq file */ + const long skiplines_, + const short format_, /* sequence file format */ + long *seqlen_, /* return seq size */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_, /* return error */ + char *seqid_) /* return seq name/info */ +{ + struct ReadSeqVars V; + + if (format_ < kMinFormat || format_ > kMaxFormat) { + *error_ = eUnknownFormat; + *seqlen_ = 0; + return NULL; + } + + V.choice = whichEntry_; + V.fname = NULL; /* don't know */ + V.seq = (char*) calloc(1, kStartLength+1); + V.maxseq = kStartLength; + V.seqlen = 0; + V.seqid = seqid_; + + V.f = fp_; + V.filestart= (ftell( fp_) == 0); + /* !! in sequential read, must remove current seq position from choice/whichEntry_ counter !! ... */ + if (V.filestart) V.nseq = 0; + else V.nseq= *nseq_; /* track where we are in file...*/ + + *V.seqid = '\0'; + V.err = 0; + V.nseq = 0; + V.isseqchar = isSeqChar; + if (V.choice == kListSequences) ; /* leave as is */ + else if (V.choice <= 0) V.choice = 1; /* default ?? */ + V.addit = (V.choice > 0); + V.allDone = false; + + readSeqMain(&V, skiplines_, format_); + + *error_ = V.err; + *seqlen_ = V.seqlen; + *nseq_ = V.nseq; + return V.seq; +} + +char *readSeq( + const short whichEntry_, /* index to sequence in file */ + const char *filename_, /* file name */ + const long skiplines_, + const short format_, /* sequence file format */ + long *seqlen_, /* return seq size */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_, /* return error */ + char *seqid_) /* return seq name/info */ +{ + struct ReadSeqVars V; + + if (format_ < kMinFormat || format_ > kMaxFormat) { + *error_ = eUnknownFormat; + *seqlen_ = 0; + return NULL; + } + + V.choice = whichEntry_; + V.fname = filename_; /* don't need to copy string, just ptr to it */ + V.seq = (char*) calloc(1, kStartLength+1); + V.maxseq = kStartLength; + V.seqlen = 0; + V.seqid = seqid_; + + V.f = NULL; + *V.seqid = '\0'; + V.err = 0; + V.nseq = 0; + V.isseqchar = isSeqChar; + if (V.choice == kListSequences) ; /* leave as is */ + else if (V.choice <= 0) V.choice = 1; /* default ?? */ + V.addit = (V.choice > 0); + V.allDone = false; + + V.f = fopen(V.fname, "r"); + V.filestart= true; + + readSeqMain(&V, skiplines_, format_); + + if (V.f != NULL) fclose(V.f); + *error_ = V.err; + *seqlen_ = V.seqlen; + *nseq_ = V.nseq; + return V.seq; +} + + + + + +char *listSeqs( + const char *filename_, /* file name */ + const long skiplines_, + const short format_, /* sequence file format */ + short *nseq_, /* number of seqs in file, for listSeqs() */ + short *error_) /* return error */ +{ + char seqid[256]; + long seqlen; + + return readSeq( kListSequences, filename_, skiplines_, format_, + &seqlen, nseq_, error_, seqid); +} + + + + +short seqFileFormat( /* return sequence format number, see ureadseq.h */ + const char *filename, + long *skiplines, /* return #lines to skip any junk like mail header */ + short *error) /* return any error value or 0 */ +{ + FILE *fseq; + short format; + + fseq = fopen(filename, "r"); + format= seqFileFormatFp( fseq, skiplines, error); + if (fseq!=NULL) fclose(fseq); + return format; +} + +short seqFileFormatFp( + FILE *fseq, + long *skiplines, /* return #lines to skip any junk like mail header */ + short *error) /* return any error value or 0 */ +{ + boolean foundDNA= false, foundIG= false, foundStrider= false, + foundGB= false, foundPIR= false, foundEMBL= false, foundNBRF= false, + foundPearson= false, foundFitch= false, foundPhylip= false, foundZuker= false, + gotolsen= false, gotpaup = false, gotasn1 = false, gotuw= false, gotMSF= false, + isfitch= false, isphylip= false, done= false; + short format= kUnknown; + int nlines= 0, k, splen= 0, otherlines= 0, aminolines= 0, dnalines= 0; + char sp[256]; + long linestart=0; + int maxlines2check=500; + +#define ReadOneLine(sp) \ + { done |= (feof(fseq)); \ + readline( fseq, sp, &linestart); \ + if (!done) { splen = strlen(sp); ++nlines; } } + + *skiplines = 0; + *error = 0; + if (fseq == NULL) { *error = eFileNotFound; return kNoformat; } + + while ( !done ) { + ReadOneLine(sp); + + /* check for mailer head & skip past if found */ + if (nlines < 4 && !done) { + if ((strstr(sp,"From ") == sp) || (strstr(sp,"Received:") == sp)) { + do { + /* skip all lines until find one blank line */ + ReadOneLine(sp); + if (!done) for (k=0; (k') { + if (sp[3] == ';') foundNBRF= true; + else foundPearson= true; + } + + else if (strstr(sp,"ID ") == sp) + foundEMBL= true; + else if (strstr(sp,"SQ ") == sp) + foundEMBL= true; + + else if (*sp == '(') + foundZuker= true; + + else { + if (nlines - *skiplines == 1) { + int ispp= 0, ilen= 0; + sscanf( sp, "%d%d", &ispp, &ilen); + if (ispp > 0 && ilen > 0) isphylip= true; + } + else if (isphylip && nlines - *skiplines == 2) { + int tseq; + tseq= getseqtype(sp+10, strlen(sp+10)); + if ( isalpha(*sp) /* 1st letter in 2nd line must be of a name */ + && (tseq != kOtherSeq)) /* sequence section must be okay */ + foundPhylip= true; + } + + for (k=0, isfitch= true; isfitch & (k < splen); k++) { + if (k % 4 == 0) isfitch &= (sp[k] == ' '); + else isfitch &= (sp[k] != ' '); + } + if (isfitch & (splen > 20)) foundFitch= true; + + /* kRNA && kDNA are fairly certain...*/ + switch (getseqtype( sp, splen)) { + case kOtherSeq: otherlines++; break; + case kAmino : if (splen>20) aminolines++; break; + case kDNA : + case kRNA : if (splen>20) dnalines++; break; + case kNucleic : break; /* not much info ? */ + } + + } + + /* pretty certain */ + if (gotolsen) { + format= kOlsen; + done= true; + } + else if (gotMSF) { + format= kMSF; + done= true; + } + else if (gotasn1) { + /* !! we need to look further and return kASNseqentry | kASNseqset */ + /* + seqentry key is Seq-entry ::= + seqset key is Bioseq-set ::= + ?? can't read these yet w/ ncbi tools ?? + Seq-submit ::= + Bioseq ::= << fails both bioseq-seq and seq-entry parsers ! + */ + if (strstr(sp,"Bioseq-set")) format= kASNseqset; + else if (strstr(sp,"Seq-entry")) format= kASNseqentry; + else format= kASN1; /* other form, we can't yet read... */ + done= true; + } + else if (gotpaup) { + format= kPAUP; + done= true; + } + + else if (gotuw) { + if (foundIG) format= kIG; /* a TOIG file from GCG for certain */ + else format= kGCG; + done= true; + } + + else if ((dnalines > 1) || done || (nlines > maxlines2check)) { + /* decide on most likely format */ + /* multichar idents: */ + if (foundStrider) format= kStrider; + else if (foundGB) format= kGenBank; + else if (foundPIR) format= kPIR; + else if (foundEMBL) format= kEMBL; + else if (foundNBRF) format= kNBRF; + /* single char idents: */ + else if (foundIG) format= kIG; + else if (foundPearson) format= kPearson; + else if (foundZuker) format= kZuker; + /* digit ident: */ + else if (foundPhylip) format= kPhylip; + /* spacing ident: */ + else if (foundFitch) format= kFitch; + /* no format chars: */ + else if (otherlines > 0) format= kUnknown; + else if (dnalines > 1) format= kPlain; + else if (aminolines > 1) format= kPlain; + else format= kUnknown; + + done= true; + } + + /* need this for possible long header in olsen format */ + else if (strstr(sp,"): ") != NULL) + maxlines2check++; + } + + if (format == kPhylip) { + /* check for interleaved or sequential -- really messy */ + int tname, tseq; + long i, j, nspp= 0, nlen= 0, ilen, leaf= 0, seq= 0; + char *ps; + + rewind(fseq); + for (i=0; i < *skiplines; i++) ReadOneLine(sp); + nlines= 0; + ReadOneLine(sp); + sscanf( sp, "%d%d", &nspp, &nlen); + ReadOneLine(sp); /* 1st seq line */ + for (ps= sp+10, ilen=0; *ps!=0; ps++) if (isprint(*ps)) ilen++; + + for (i= 1; i=9) seq += 10; /* pretty certain not ileaf */ + else { + if (tseq != tname) leaf++; else seq++; + if (tname == kDNA || tname == kRNA) seq++; else leaf++; + } + + if (ilen <= nlen && j<9) { + if (tname == kOtherSeq) leaf += 10; + else if (tname == kAmino || tname == kDNA || tname == kRNA) seq++; else leaf++; + } + else if (ilen > nlen) { + ilen= 0; + } + } + for ( nspp *= 2 ; i nlen) { + if (j>9) leaf += 10; /* must be a name here for sequent */ + else if (tname == kOtherSeq) seq += 10; + ilen= 0; + } + } + + if (leaf > seq) format= kPhylip4; + else format= kPhylip2; + } + + return(format); +#undef ReadOneLine +} /* SeqFileFormat */ + + + + +unsigned long GCGchecksum( const char *seq, const long seqlen, unsigned long *checktotal) +/* GCGchecksum */ +{ + register long i, check = 0, count = 0; + + for (i = 0; i < seqlen; i++) { + count++; + check += count * to_upper(seq[i]); + if (count == 57) count = 0; + } + check %= 10000; + *checktotal += check; + *checktotal %= 10000; + return check; +} + +/* Table of CRC-32's of all single byte values (made by makecrc.c of ZIP source) */ +const unsigned long crctab[] = { + 0x00000000L, 0x77073096L, 0xee0e612cL, 0x990951baL, 0x076dc419L, + 0x706af48fL, 0xe963a535L, 0x9e6495a3L, 0x0edb8832L, 0x79dcb8a4L, + 0xe0d5e91eL, 0x97d2d988L, 0x09b64c2bL, 0x7eb17cbdL, 0xe7b82d07L, + 0x90bf1d91L, 0x1db71064L, 0x6ab020f2L, 0xf3b97148L, 0x84be41deL, + 0x1adad47dL, 0x6ddde4ebL, 0xf4d4b551L, 0x83d385c7L, 0x136c9856L, + 0x646ba8c0L, 0xfd62f97aL, 0x8a65c9ecL, 0x14015c4fL, 0x63066cd9L, + 0xfa0f3d63L, 0x8d080df5L, 0x3b6e20c8L, 0x4c69105eL, 0xd56041e4L, + 0xa2677172L, 0x3c03e4d1L, 0x4b04d447L, 0xd20d85fdL, 0xa50ab56bL, + 0x35b5a8faL, 0x42b2986cL, 0xdbbbc9d6L, 0xacbcf940L, 0x32d86ce3L, + 0x45df5c75L, 0xdcd60dcfL, 0xabd13d59L, 0x26d930acL, 0x51de003aL, + 0xc8d75180L, 0xbfd06116L, 0x21b4f4b5L, 0x56b3c423L, 0xcfba9599L, + 0xb8bda50fL, 0x2802b89eL, 0x5f058808L, 0xc60cd9b2L, 0xb10be924L, + 0x2f6f7c87L, 0x58684c11L, 0xc1611dabL, 0xb6662d3dL, 0x76dc4190L, + 0x01db7106L, 0x98d220bcL, 0xefd5102aL, 0x71b18589L, 0x06b6b51fL, + 0x9fbfe4a5L, 0xe8b8d433L, 0x7807c9a2L, 0x0f00f934L, 0x9609a88eL, + 0xe10e9818L, 0x7f6a0dbbL, 0x086d3d2dL, 0x91646c97L, 0xe6635c01L, + 0x6b6b51f4L, 0x1c6c6162L, 0x856530d8L, 0xf262004eL, 0x6c0695edL, + 0x1b01a57bL, 0x8208f4c1L, 0xf50fc457L, 0x65b0d9c6L, 0x12b7e950L, + 0x8bbeb8eaL, 0xfcb9887cL, 0x62dd1ddfL, 0x15da2d49L, 0x8cd37cf3L, + 0xfbd44c65L, 0x4db26158L, 0x3ab551ceL, 0xa3bc0074L, 0xd4bb30e2L, + 0x4adfa541L, 0x3dd895d7L, 0xa4d1c46dL, 0xd3d6f4fbL, 0x4369e96aL, + 0x346ed9fcL, 0xad678846L, 0xda60b8d0L, 0x44042d73L, 0x33031de5L, + 0xaa0a4c5fL, 0xdd0d7cc9L, 0x5005713cL, 0x270241aaL, 0xbe0b1010L, + 0xc90c2086L, 0x5768b525L, 0x206f85b3L, 0xb966d409L, 0xce61e49fL, + 0x5edef90eL, 0x29d9c998L, 0xb0d09822L, 0xc7d7a8b4L, 0x59b33d17L, + 0x2eb40d81L, 0xb7bd5c3bL, 0xc0ba6cadL, 0xedb88320L, 0x9abfb3b6L, + 0x03b6e20cL, 0x74b1d29aL, 0xead54739L, 0x9dd277afL, 0x04db2615L, + 0x73dc1683L, 0xe3630b12L, 0x94643b84L, 0x0d6d6a3eL, 0x7a6a5aa8L, + 0xe40ecf0bL, 0x9309ff9dL, 0x0a00ae27L, 0x7d079eb1L, 0xf00f9344L, + 0x8708a3d2L, 0x1e01f268L, 0x6906c2feL, 0xf762575dL, 0x806567cbL, + 0x196c3671L, 0x6e6b06e7L, 0xfed41b76L, 0x89d32be0L, 0x10da7a5aL, + 0x67dd4accL, 0xf9b9df6fL, 0x8ebeeff9L, 0x17b7be43L, 0x60b08ed5L, + 0xd6d6a3e8L, 0xa1d1937eL, 0x38d8c2c4L, 0x4fdff252L, 0xd1bb67f1L, + 0xa6bc5767L, 0x3fb506ddL, 0x48b2364bL, 0xd80d2bdaL, 0xaf0a1b4cL, + 0x36034af6L, 0x41047a60L, 0xdf60efc3L, 0xa867df55L, 0x316e8eefL, + 0x4669be79L, 0xcb61b38cL, 0xbc66831aL, 0x256fd2a0L, 0x5268e236L, + 0xcc0c7795L, 0xbb0b4703L, 0x220216b9L, 0x5505262fL, 0xc5ba3bbeL, + 0xb2bd0b28L, 0x2bb45a92L, 0x5cb36a04L, 0xc2d7ffa7L, 0xb5d0cf31L, + 0x2cd99e8bL, 0x5bdeae1dL, 0x9b64c2b0L, 0xec63f226L, 0x756aa39cL, + 0x026d930aL, 0x9c0906a9L, 0xeb0e363fL, 0x72076785L, 0x05005713L, + 0x95bf4a82L, 0xe2b87a14L, 0x7bb12baeL, 0x0cb61b38L, 0x92d28e9bL, + 0xe5d5be0dL, 0x7cdcefb7L, 0x0bdbdf21L, 0x86d3d2d4L, 0xf1d4e242L, + 0x68ddb3f8L, 0x1fda836eL, 0x81be16cdL, 0xf6b9265bL, 0x6fb077e1L, + 0x18b74777L, 0x88085ae6L, 0xff0f6a70L, 0x66063bcaL, 0x11010b5cL, + 0x8f659effL, 0xf862ae69L, 0x616bffd3L, 0x166ccf45L, 0xa00ae278L, + 0xd70dd2eeL, 0x4e048354L, 0x3903b3c2L, 0xa7672661L, 0xd06016f7L, + 0x4969474dL, 0x3e6e77dbL, 0xaed16a4aL, 0xd9d65adcL, 0x40df0b66L, + 0x37d83bf0L, 0xa9bcae53L, 0xdebb9ec5L, 0x47b2cf7fL, 0x30b5ffe9L, + 0xbdbdf21cL, 0xcabac28aL, 0x53b39330L, 0x24b4a3a6L, 0xbad03605L, + 0xcdd70693L, 0x54de5729L, 0x23d967bfL, 0xb3667a2eL, 0xc4614ab8L, + 0x5d681b02L, 0x2a6f2b94L, 0xb40bbe37L, 0xc30c8ea1L, 0x5a05df1bL, + 0x2d02ef8dL +}; + +unsigned long CRC32checksum(const char *seq, const long seqlen, unsigned long *checktotal) +/*CRC32checksum: modified from CRC-32 algorithm found in ZIP compression source */ +{ + register unsigned long c = 0xffffffffL; + register long n = seqlen; + + while (n--) { + c = crctab[((int)c ^ (to_upper(*seq))) & 0xff] ^ (c >> 8); + seq++; /* fixed aug'98 finally */ + } + c= c ^ 0xffffffffL; + *checktotal += c; + return c; +} + + + + +short getseqtype( const char *seq, const long seqlen) +{ /* return sequence kind: kDNA, kRNA, kProtein, kOtherSeq, ??? */ + char c; + short i, maxtest; + short na = 0, aa = 0, po = 0, nt = 0, nu = 0, ns = 0, no = 0; + + maxtest = min(300, seqlen); + for (i = 0; i < maxtest; i++) { + c = to_upper(seq[i]); + if (strchr(protonly, c)) po++; + else if (strchr(primenuc,c)) { + na++; + if (c == 'T') nt++; + else if (c == 'U') nu++; + } + else if (strchr(aminos,c)) aa++; + else if (strchr(seqsymbols,c)) ns++; + else if (isalpha(c)) no++; + } + + if ((no > 0) || (po+aa+na == 0)) return kOtherSeq; + /* ?? test for probability of kOtherSeq ?, e.g., + else if (po+aa+na / maxtest < 0.70) return kOtherSeq; + */ + else if (po > 0) return kAmino; + else if (aa == 0) { + if (nu > nt) return kRNA; + else return kDNA; + } + else if (na > aa) return kNucleic; + else return kAmino; +} /* getseqtype */ + + +char* compressSeq( const char gapc, const char *seq, const long seqlen, long *newlen) +{ + register char *a, *b; + register long i; + char *newseq; + + *newlen= 0; + if (!seq) return NULL; + newseq = (char*) malloc(seqlen+1); + if (!newseq) return NULL; + for (a= (char*)seq, b=newseq, i=0; *a!=0; a++) + if (*a != gapc) { + *b++= *a; + i++; + } + *b= '\0'; + newseq = (char*) realloc(newseq, i+1); + *newlen= i; + return newseq; +} + + + +/*** +char *rtfhead = "{\\rtf1\\defformat\\mac\\deff2 \ +{\\fonttbl\ + {\\f1\\fmodern Courier;}{\\f2\\fmodern Monaco;}\ + {\\f3\\fswiss Helvetica;}{\\f4\\fswiss Geneva;}\ + {\\f5\\froman Times;}{\\f6\\froman Palatino;}\ + {\\f7\\froman New Century Schlbk;}{\\f8\\ftech Symbol;}}\ +{\\stylesheet\ + {\\s1 \\f5\\fs20 \\sbasedon0\\snext1 name;}\ + {\\s2 \\f3\\fs20 \\sbasedon0\\snext2 num;}\ + {\\s3 \\f1\\f21 \\sbasedon0\\snext3 seq;}}"; + +char *rtftail = "}"; +****/ + +short writeSeq(FILE *outf, const char *seq, const long seqlen, + const short outform, const char *seqid) +/* dump sequence to standard output */ +{ + const short kSpaceAll = -9; +#define kMaxseqwidth 250 + + boolean baseonlynum= false; /* nocountsymbols -- only count true bases, not "-" */ + short numline = 0; /* only true if we are writing seq number line (for interleave) */ + boolean numright = false, numleft = false; + boolean nameright = false, nameleft = false; + short namewidth = 8, numwidth = 8; + short spacer = 0, width = 50, tab = 0; + /* new parameters: width, spacer, those above... */ + + short linesout = 0, seqtype = kNucleic; + long i, j, l, l1, ibase; + char idword[31], endstr[10]; + char seqnamestore[128], *seqname = seqnamestore; + char s[kMaxseqwidth], *cp; + char nameform[10], numform[10], nocountsymbols[10]; + unsigned long checksum = 0, checktotal = 0; + + gPretty.atseq++; + skipwhitespace(seqid); + l = min(128, strlen(seqid)); + strncpy( seqnamestore, seqid, l); + seqname[l] = 0; + + sscanf( seqname, "%30s", idword); + sprintf(numform, "%d", seqlen); + numwidth= strlen(numform)+1; + nameform[0]= '\0'; + + if (strstr(seqname,"checksum") != NULL) { + cp = strstr(seqname,"bases"); + if (cp!=NULL) { + for ( ; (cp!=seqname) && (*cp!=','); cp--) ; + if (cp!=seqname) *cp=0; + } + } + + strcpy( endstr,""); + l1 = 0; + + if (outform == kGCG || outform == kMSF) + checksum = GCGchecksum(seq, seqlen, &checktotal); + else + checksum = seqchecksum(seq, seqlen, &checktotal); + + switch (outform) { + + case kPlain: + case kUnknown: /* no header, just sequence */ + strcpy(endstr,"\n"); /* end w/ extra blank line */ + break; + + case kOlsen: /* Olsen seq. editor takes plain nucs OR Genbank */ + case kGenBank: + fprintf(outf,"LOCUS %s %d bp\n", idword, seqlen); + fprintf(outf,"DEFINITION %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf,"ORIGIN \n"); + spacer = 11; + numleft = true; + numwidth = 8; /* dgg. 1Feb93, patch for GDE fail to read short numwidth */ + strcpy(endstr, "\n//"); + linesout += 4; + break; + + case kPIR: + /* somewhat like genbank... \\\*/ + /* fprintf(outf,"\\\\\\\n"); << only at top of file, not each entry... */ + fprintf(outf,"ENTRY %s \n", idword); + fprintf(outf,"TITLE %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf,"SEQUENCE \n"); + numwidth = 7; + width= 30; + spacer = kSpaceAll; + numleft = true; + strcpy(endstr, "\n///"); + /* run a top number line for PIR */ + for (j=0; jP1;%s\n", idword); + else + fprintf(outf,">DL;%s\n", idword); + fprintf(outf,"%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + spacer = 11; + strcpy(endstr,"*\n"); + linesout += 3; + break; + + case kEMBL: + fprintf(outf,"ID %s\n", idword); + /* fprintf(outf,"AC %s\n", accnum); */ + fprintf(outf,"DE %s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + fprintf(outf,"SQ %d BP\n", seqlen); + strcpy(endstr, "\n//"); /* 11Oct90: bug fix*/ + tab = 4; /** added 31jan91 */ + spacer = 11; /** added 31jan91 */ + width = 60; + linesout += 4; + break; + + case kGCG: + fprintf(outf,"%s\n", seqname); + /* fprintf(outf,"ACCESSION %s\n", accnum); */ + fprintf(outf," %s Length: %d (today) Check: %d ..\n", idword, seqlen, checksum); + spacer = 11; + numleft = true; + strcpy(endstr, "\n"); /* this is insurance to help prevent misreads at eof */ + linesout += 3; + break; + + case kStrider: /* ?? map ?*/ + fprintf(outf,"; ### from DNA Strider ;-)\n"); + fprintf(outf,"; DNA sequence %s, %d bases, %X checksum.\n;\n", seqname, seqlen, checksum); + strcpy(endstr, "\n//"); + linesout += 3; + break; + + case kFitch: + fprintf(outf,"%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + spacer = 4; + width = 60; + linesout += 1; + break; + + case kPhylip2: + case kPhylip4: + /* this is version 3.2/3.4 -- simplest way to write + version 3.3 is to write as version 3.2, then + re-read file and interleave the species lines */ + if (strlen(idword)>10) idword[10] = 0; + fprintf(outf,"%-10s ",idword); + l1 = -1; + tab = 12; + spacer = 11; + break; + + case kASN1: + seqtype= getseqtype(seq, seqlen); + switch (seqtype) { + case kDNA : cp= "dna"; break; + case kRNA : cp= "rna"; break; + case kNucleic : cp= "na"; break; + case kAmino : cp= "aa"; break; + case kOtherSeq: cp= "not-set"; break; + } + fprintf(outf," seq {\n"); + fprintf(outf," id { local id %d },\n", gPretty.atseq); + fprintf(outf," descr { title \"%s\" },\n", seqid); + fprintf(outf," inst {\n"); + fprintf(outf," repr raw, mol %s, length %d, topology linear,\n", cp, seqlen); + fprintf(outf," seq-data\n"); + if (seqtype == kAmino) + fprintf(outf," iupacaa \""); + else + fprintf(outf," iupacna \""); + l1 = 17; + spacer = 0; + width = 78; + tab = 0; + strcpy(endstr,"\"\n } } ,"); + linesout += 7; + break; + + case kPAUP: + nameleft= true; + namewidth = 9; + spacer = 21; + width = 100; + tab = 0; /* 1; */ + /* strcpy(endstr,";\nend;"); << this is end of all seqs.. */ + /* do a header comment line for paup */ + fprintf(outf,"[Name: %-16s Len:%6d Check: %8X]\n", idword, seqlen, checksum); + linesout += 1; + break; + + case kPretty: + numline= gPretty.numline; + baseonlynum= gPretty.baseonlynum; + namewidth = gPretty.namewidth; + numright = gPretty.numright; + numleft = gPretty.numleft; + nameright = gPretty.nameright; + nameleft = gPretty.nameleft; + spacer = gPretty.spacer + 1; + width = gPretty.seqwidth; + tab = gPretty.tab; + /* also add rtf formatting w/ font, size, style */ + if (gPretty.nametop) { + fprintf(outf,"Name: %-16s Len:%6d Check: %8X\n", idword, seqlen, checksum); + linesout++; + } + break; + + case kMSF: + fprintf(outf," Name: %-16s Len:%6d Check: %5d Weight: 1.00\n", + idword, seqlen, checksum); + linesout++; + nameleft= true; + namewidth= 15; /* need MAX namewidth here... */ + sprintf(nameform, "%%+%ds ",namewidth); + spacer = 11; + width = 50; + tab = 0; /* 1; */ + break; + + case kIG: + fprintf(outf,";%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + fprintf(outf,"%s\n", idword); + strcpy(endstr,"1"); /* == linear dna */ + linesout += 2; + break; + + default : + case kZuker: /* don't attempt Zuker's ftn format */ + case kPearson: + fprintf(outf,">%s, %d bases, %X checksum.\n", seqname, seqlen, checksum); + linesout += 1; + break; + } + + if (*nameform==0) sprintf(nameform, "%%%d.%ds ",namewidth,namewidth); + if (numline) sprintf(numform, "%%%ds ",numwidth); + else sprintf(numform, "%%%dd ",numwidth); + strcpy( nocountsymbols, kNocountsymbols); + if (baseonlynum) { + if (strchr(nocountsymbols,gPretty.gapchar)==NULL) { + strcat(nocountsymbols," "); + nocountsymbols[strlen(nocountsymbols)-1]= gPretty.gapchar; + } + if (gPretty.domatch && (cp=strchr(nocountsymbols,gPretty.matchchar))!=NULL) { + *cp= ' '; + } + } + + if (numline) { + *idword= 0; + } + + width = min(width,kMaxseqwidth); + for (i=0, l=0, ibase = 1; i < seqlen; ) { + + if (l1 < 0) l1 = 0; + else if (l1 == 0) { + if (nameleft) fprintf(outf, nameform, idword); + if (numleft) { if (numline) fprintf(outf, numform, ""); + else fprintf(outf, numform, ibase);} + for (j=0; jb)?a:b +#define skipwhitespace(string) {while (*string <= ' ' && *string != 0) string++;} + + /* NLM strings */ +#define is_upper(c) ('A'<=(c) && (c)<='Z') +#define is_lower(c) ('a'<=(c) && (c)<='z') +#define to_lower(c) ((char)(is_upper(c) ? (c)+' ' : (c))) +#define to_upper(c) ((char)(is_lower(c) ? (c)-' ' : (c))) + + + /* readSeq errors */ +#define eFileNotFound -1 +#define eNoData -2 +#define eMemFull -3 +#define eItemNotFound -4 +#define eOneFormat -5 +#define eUnequalSize -6 +#define eFileCreate -7 +#define eUnknownFormat -8 +#define eOptionBad -9 +#define eASNerr -10 + + /* magic number for readSeq(whichEntry) to give seq list */ +#define kListSequences -1 + + /* sequence types parsed by getseqtype */ +#define kOtherSeq 0 +#define kDNA 1 +#define kRNA 2 +#define kNucleic 3 +#define kAmino 4 + + /* formats known to readSeq */ +#define kIG 1 +#define kGenBank 2 +#define kNBRF 3 +#define kEMBL 4 +#define kGCG 5 +#define kStrider 6 +#define kFitch 7 +#define kPearson 8 +#define kZuker 9 +#define kOlsen 10 +#define kPhylip2 11 +#define kPhylip4 12 +#define kPhylip3 kPhylip4 +#define kPhylip kPhylip4 +#define kPlain 13 /* keep this at #13 */ +#define kPIR 14 +#define kMSF 15 +#define kASN1 16 +#define kPAUP 17 +#define kPretty 18 +#define kVienna 19 + +#define kMaxFormat 19 +#define kMinFormat 1 +#define kNoformat -1 /* format not tested */ +#define kUnknown 0 /* format not determinable */ + + /* subsidiary types */ +#define kASNseqentry 51 +#define kASNseqset 52 + +#define kPhylipInterleave 61 +#define kPhylipSequential 62 + + +typedef struct { + boolean isactive, baseonlynum; + boolean numright, numleft, numtop, numbot; + boolean nameright, nameleft, nametop; + boolean noleaves, domatch, degap; + char matchchar, gapchar; + short numline, atseq; + short namewidth, numwidth; + short interline, spacer, seqwidth, tab; + } prettyopts; + +#define gPrettyInit(p) { \ + p.isactive=false;\ + p.baseonlynum=true;\ + p.numline= p.atseq= 0;\ + p.numright= p.numleft= p.numtop= p.numbot= false;\ + p.nameright= p.nameleft= p.nametop= false;\ + p.noleaves= p.domatch= p.degap= false;\ + p.matchchar='.';\ + p.gapchar='-';\ + p.namewidth=8;\ + p.numwidth=5;\ + p.interline=1;\ + p.spacer=10;\ + p.seqwidth=50;\ + p.tab=0; } + +#ifdef UREADSEQ_G +prettyopts gPretty; +#else +extern prettyopts gPretty; +#endif + + +#ifdef __cplusplus +extern "C" { +#endif + +extern short seqFileFormat(const char *filename, long *skiplines, short *error ); +extern short seqFileFormatFp(FILE *fseq, long *skiplines, short *error ); + +extern char *listSeqs(const char *filename, const long skiplines, + const short format, short *nseq, short *error ); + +extern char *readSeq(const short whichEntry, const char *filename, + const long skiplines, const short format, + long *seqlen, short *nseq, short *error, char *seqid ); + +extern char *readSeqFp(const short whichEntry_, FILE *fp_, + const long skiplines_, const short format_, + long *seqlen_, short *nseq_, short *error_, char *seqid_ ); + +extern short writeSeq(FILE *outf, const char *seq, const long seqlen, + const short outform, const char *seqid ); + +extern unsigned long CRC32checksum(const char *seq, const long seqlen, unsigned long *checktotal); +extern unsigned long GCGchecksum(const char *seq, const long seqlen, unsigned long *checktotal); +#ifdef SMALLCHECKSUM +#define seqchecksum GCGchecksum +#else +#define seqchecksum CRC32checksum +#endif + +extern short getseqtype(const char *seq, const long seqlen ); +extern char *compressSeq( const char gapc, const char *seq, const long seqlen, long *newlen); + +#ifdef NCBI + +extern char *listASNSeqs(const char *filename, const long skiplines, + const short format, short *nseq, short *error ); + +extern char *readASNSeq(const short whichEntry, const char *filename, + const long skiplines, const short format, + long *seqlen, short *nseq, short *error, char **seqid ); +#endif + + + /* patches for some missing string.h stuff */ +extern int Strcasecmp(const char *a, const char *b); +extern int Strncasecmp(const char *a, const char *b, long maxn); + +#ifdef __cplusplus +} +#endif + +#endif /*UREADSEQ_H*/ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.h.orig b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.h.orig new file mode 100755 index 00000000..cb5a87c5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Readseq/ureadseq.h.orig @@ -0,0 +1,169 @@ +/* File: ureadseq.h + * + * Header for module UReadSeq + */ + +#ifndef UREADSEQ_H +#define UREADSEQ_H + + + +typedef char boolean; +#define NEWLINE '\n' +#define false 0 +#define true 1 +#define min(a,b) (ab)?a:b +#define skipwhitespace(string) {while (*string <= ' ' && *string != 0) string++;} + + /* NLM strings */ +#define is_upper(c) ('A'<=(c) && (c)<='Z') +#define is_lower(c) ('a'<=(c) && (c)<='z') +#define to_lower(c) ((char)(is_upper(c) ? (c)+' ' : (c))) +#define to_upper(c) ((char)(is_lower(c) ? (c)-' ' : (c))) + + + /* readSeq errors */ +#define eFileNotFound -1 +#define eNoData -2 +#define eMemFull -3 +#define eItemNotFound -4 +#define eOneFormat -5 +#define eUnequalSize -6 +#define eFileCreate -7 +#define eUnknownFormat -8 +#define eOptionBad -9 +#define eASNerr -10 + + /* magic number for readSeq(whichEntry) to give seq list */ +#define kListSequences -1 + + /* sequence types parsed by getseqtype */ +#define kOtherSeq 0 +#define kDNA 1 +#define kRNA 2 +#define kNucleic 3 +#define kAmino 4 + + /* formats known to readSeq */ +#define kIG 1 +#define kGenBank 2 +#define kNBRF 3 +#define kEMBL 4 +#define kGCG 5 +#define kStrider 6 +#define kFitch 7 +#define kPearson 8 +#define kZuker 9 +#define kOlsen 10 +#define kPhylip2 11 +#define kPhylip4 12 +#define kPhylip3 kPhylip4 +#define kPhylip kPhylip4 +#define kPlain 13 /* keep this at #13 */ +#define kPIR 14 +#define kMSF 15 +#define kASN1 16 +#define kPAUP 17 +#define kPretty 18 + +#define kMaxFormat 18 +#define kMinFormat 1 +#define kNoformat -1 /* format not tested */ +#define kUnknown 0 /* format not determinable */ + + /* subsidiary types */ +#define kASNseqentry 51 +#define kASNseqset 52 + +#define kPhylipInterleave 61 +#define kPhylipSequential 62 + + +typedef struct { + boolean isactive, baseonlynum; + boolean numright, numleft, numtop, numbot; + boolean nameright, nameleft, nametop; + boolean noleaves, domatch, degap; + char matchchar, gapchar; + short numline, atseq; + short namewidth, numwidth; + short interline, spacer, seqwidth, tab; + } prettyopts; + +#define gPrettyInit(p) { \ + p.isactive=false;\ + p.baseonlynum=true;\ + p.numline= p.atseq= 0;\ + p.numright= p.numleft= p.numtop= p.numbot= false;\ + p.nameright= p.nameleft= p.nametop= false;\ + p.noleaves= p.domatch= p.degap= false;\ + p.matchchar='.';\ + p.gapchar='-';\ + p.namewidth=8;\ + p.numwidth=5;\ + p.interline=1;\ + p.spacer=10;\ + p.seqwidth=50;\ + p.tab=0; } + +#ifdef UREADSEQ_G +prettyopts gPretty; +#else +extern prettyopts gPretty; +#endif + + +#ifdef __cplusplus +extern "C" { +#endif + +extern short seqFileFormat(const char *filename, long *skiplines, short *error ); +extern short seqFileFormatFp(FILE *fseq, long *skiplines, short *error ); + +extern char *listSeqs(const char *filename, const long skiplines, + const short format, short *nseq, short *error ); + +extern char *readSeq(const short whichEntry, const char *filename, + const long skiplines, const short format, + long *seqlen, short *nseq, short *error, char *seqid ); + +extern char *readSeqFp(const short whichEntry_, FILE *fp_, + const long skiplines_, const short format_, + long *seqlen_, short *nseq_, short *error_, char *seqid_ ); + +extern short writeSeq(FILE *outf, const char *seq, const long seqlen, + const short outform, const char *seqid ); + +extern unsigned long CRC32checksum(const char *seq, const long seqlen, unsigned long *checktotal); +extern unsigned long GCGchecksum(const char *seq, const long seqlen, unsigned long *checktotal); +#ifdef SMALLCHECKSUM +#define seqchecksum GCGchecksum +#else +#define seqchecksum CRC32checksum +#endif + +extern short getseqtype(const char *seq, const long seqlen ); +extern char *compressSeq( const char gapc, const char *seq, const long seqlen, long *newlen); + +#ifdef NCBI + +extern char *listASNSeqs(const char *filename, const long skiplines, + const short format, short *nseq, short *error ); + +extern char *readASNSeq(const short whichEntry, const char *filename, + const long skiplines, const short format, + long *seqlen, short *nseq, short *error, char **seqid ); +#endif + + + /* patches for some missing string.h stuff */ +extern int Strcasecmp(const char *a, const char *b); +extern int Strncasecmp(const char *a, const char *b, long maxn); + +#ifdef __cplusplus +} +#endif + +#endif /*UREADSEQ_H*/ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/THANKS b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/THANKS new file mode 100755 index 00000000..6908c26e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/THANKS @@ -0,0 +1,7 @@ +Sebastian Bonhoeffer's implementation of partition function folding served + as a precursor to our part_func.c +Manfred Tacker hacked constrained folding into fold.c for the first time +Martin Fekete made the first attempts at "alignment folding" + +Thanks also to everyone who helped testing and finding bugs, especially +Christoph Flamm, Martijn Huynen, Baerbel Krakhofer, and many more diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/b2ct.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/b2ct.Po new file mode 100755 index 00000000..284f603c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/b2ct.Po @@ -0,0 +1,83 @@ +b2ct.o b2ct.o: b2ct.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/popt.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/popt.Po new file mode 100755 index 00000000..22193500 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/.deps/popt.Po @@ -0,0 +1,87 @@ +popt.o popt.o: popt.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/endian.h /usr/include/bits/endian.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/local/lib/gcc/i686-pc-linux-gnu/3.4.1/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Fold b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Fold new file mode 100755 index 00000000..8e3c2124 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Fold @@ -0,0 +1,15 @@ +#!/bin/csh -f +# This is an example script that demonstrates how to automatically convert +# seqences from databanks into a format suitable for RNAfold and pipe the +# result to RNAfold. +@ n=$#argv +if ( $n == 0 ) goto usage +if !( -f $argv[$n] ) goto nofile +readseq -f19 -pipe $argv[$n] | sed -e "/^>/\!s/[Tt]/U/g" | RNAfold $argv[1-$n] +exit +nofile: +echo "couldn't open file " $argv[$n] +usage: +echo "usage: Fold [RNAfold_options] sequence_file" +exit -1 + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Makefile b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Makefile new file mode 100755 index 00000000..edb77d2a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/Makefile @@ -0,0 +1,457 @@ +# Makefile.in generated by automake 1.9.5 from Makefile.am. +# Utils/Makefile. Generated from Makefile.in by configure. + +# Copyright (C) 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, +# 2003, 2004, 2005 Free Software Foundation, Inc. +# This Makefile.in is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + + + + +SOURCES = b2ct.c popt.c + +srcdir = . +top_srcdir = .. + +pkgdatadir = $(datadir)/ViennaRNA +pkglibdir = $(libdir)/ViennaRNA +pkgincludedir = $(includedir)/ViennaRNA +top_builddir = .. +am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd +INSTALL = /usr/bin/install -c +install_sh_DATA = $(install_sh) -c -m 644 +install_sh_PROGRAM = $(install_sh) -c +install_sh_SCRIPT = $(install_sh) -c +INSTALL_HEADER = $(INSTALL_DATA) +transform = $(program_transform_name) +NORMAL_INSTALL = : +PRE_INSTALL = : +POST_INSTALL = : +NORMAL_UNINSTALL = : +PRE_UNINSTALL = : +POST_UNINSTALL = : +build_triplet = x86_64-unknown-linux-gnu +host_triplet = x86_64-unknown-linux-gnu +pkgbin_PROGRAMS = b2ct$(EXEEXT) popt$(EXEEXT) +subdir = Utils +DIST_COMMON = README $(srcdir)/Makefile.am $(srcdir)/Makefile.in +ACLOCAL_M4 = $(top_srcdir)/aclocal.m4 +am__aclocal_m4_deps = $(top_srcdir)/configure.in +am__configure_deps = $(am__aclocal_m4_deps) $(CONFIGURE_DEPENDENCIES) \ + $(ACLOCAL_M4) +mkinstalldirs = $(install_sh) -d +CONFIG_HEADER = $(top_builddir)/config.h +CONFIG_CLEAN_FILES = +am__installdirs = "$(DESTDIR)$(pkgbindir)" "$(DESTDIR)$(pkgbindir)" +pkgbinPROGRAMS_INSTALL = $(INSTALL_PROGRAM) +PROGRAMS = $(pkgbin_PROGRAMS) +b2ct_SOURCES = b2ct.c +b2ct_OBJECTS = b2ct.$(OBJEXT) +b2ct_LDADD = $(LDADD) +b2ct_DEPENDENCIES = +popt_SOURCES = popt.c +popt_OBJECTS = popt.$(OBJEXT) +popt_LDADD = $(LDADD) 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They're not +installed by default. + +Fold automatically converts sequence files from databanks using readseq + and feeds the converted sequence to RNAfold + +b2ct.c converts the bracket notation produced by RNAfold into an '.ct' file, + as produced by Zukers mfold. + +b2mt.pl perl script that converts a secondary structure in bracket notation + into a list of x y values that can be plotted to obtain the + "mountain"-representation of an RNA secondary structure. E.g.: + RNAfold < foo.seq | b2mt.pl | xmgr -pipe + +mountain.pl + produces a generalized mountain presentation and the pre postion + entropy as a measure of well-definedness from the base pair + probabilities contained in an PostScript dotplot. E.g: + RNAfold < foo.seq; mountain.pl dot.ps | xmgr -pipe + +dpzoom.pl extract a portion of a dot plot produced by RNAfold -p + e.g.: to extract the structure of bases 7361 to 7600 from the + folding of a complete HIV sequence use + dpzoom.pl -f 7361 -l 7600 HIV_dp.ps > RRE_dp.ps + +rotate_ss.pl + rotate or flip the coordinates of an RNA secondary structure plot. + E.g. to rotate the file foo_ss.ps by 90 degrees and get a + clockwise drawing (instead of the default counter-clockwise), use + rotate_ss.pl -a 90 -m foo_ss.ps > foo90_ss.ps + +relplot.pl + add reliability information to a RNA seondary structure plot + in the form of color annotation. The script computes the + "positional entropy" S(i) = - Sum p(ij) log(p(ij)) and encodes + it as color hue, ranging from red (low entropy, well-defined) via + green to blue and violet (high entropy, ill-defined). Apart + from the secondary structure plot the dot plot containing the + pair probabilities p(ij) is needed. Use as + replot.pl foo_ss.ps foo_dp.ps > foo_rss.ps \ No newline at end of file diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2ct.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2ct.c new file mode 100755 index 00000000..5b0dc4bf --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2ct.c @@ -0,0 +1,152 @@ +/* Last Changed Time-stamp: <2001-09-07 10:17:47 ivo> */ +/* This program converts the bracket notation for RNA secondary structures + produced by RNAfold to .ct files used by Michael Zukers Program. + To compile enter: + cc -o b2ct b2ct.c + And use as + b2ct < structure_file > ct_file.ct + or + RNAfold < sequence_file | b2ct > ct_file.ct +*/ + +#include +#include +#include +#define MAXLENGTH 30000 + +void write_ct_file(char *fname, char *sequence, char *structure, char *name, + float energy); +short *make_pair_table(const char *structure); +void *space(unsigned size); +void nrerror(char *message); + +int main(void) +{ + char line[MAXLENGTH+1]; + char *string=NULL, *structure=NULL, *name=NULL; + float energy; + int n=0; + + while (fgets(line, MAXLENGTH, stdin)!=NULL) { + if (strcmp(line,"@")==0) break; + + switch (line[0]) { + case '>': name = (char *) space(strlen(line)); + sscanf(line,"> %s", name); + break; + case '.': + case '(': + case ')': structure = (char *) space(strlen(line)); + if (sscanf(line,"%s (%f)", structure, &energy)!=2) { + free(structure); structure=NULL; break; + } + n++; + break; + default: string = (char *) space(strlen(line)+1); + sscanf(line, "%s", string); + } + if (structure!=NULL) { + if (name==NULL) { + name = (char *) space(10); + sprintf(name,"%d",n); + } + write_ct_file("-", string, structure, name, energy); + free(string); + free(structure); + free(name); + string = structure = name = NULL; + } + } + return 0; +} + +void write_ct_file(char *fname, char *sequence, char *structure, char *name, + float energy) +{ + int i, length; + short *table; + FILE *ct; + + length = strlen(structure); + if ((table = make_pair_table(structure))==NULL) { + return; + } + if (length!=strlen(sequence)) + nrerror("sequence and structure have unequal length"); + + if (strcmp(fname,"-")==0) + ct = stdout; + else { + ct = fopen(fname, "a"); + if (ct==NULL) nrerror("can't open .ct file"); + } + + fprintf(ct, "%5d ENERGY = %7.1f %s\n", length, energy, name); + for (i=1; i<=length; i++) + fprintf(ct, "%5d %c %5d %4d %4d %4d\n", + i, sequence[i-1], i-1, (i+1)%(length+1), table[i], i); + if (strcmp(fname,"-")) + fclose(ct); + else fflush(ct); +} + +short *make_pair_table(const char *structure) +{ + /* returns array representation of structure. + table[i] is 0 if unpaired or j if (i.j) pair. */ + int i,j,hx; + int length; + short *stack; + short *table; + + length = strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + table = (short *) space(sizeof(short)*(length+2)); + table[0] = length; + + for (hx=0, i=1; i<=length; i++) { + switch (structure[i-1]) { + case '(': + stack[hx++]=i; + break; + case ')': + j = stack[--hx]; + if (hx<0) { + fprintf(stderr, "unbalanced brackets in %s\n", structure); + free(stack); free(table); return NULL; + } + table[i]=j; + table[j]=i; + break; + default: /* unpaired base, usually '.' */ + table[i]= 0; + break; + } + } + free(stack); + if (hx!=0) { + fprintf(stderr, "unbalanced brackets %s\n", structure); + free(table); + return NULL; + } + return(table); +} + +void *space(unsigned size) +{ + void *pointer; + + if ( (pointer = (void *) calloc(1, size)) == NULL) { + fprintf(stderr,"SPACE: requested size: %d\n", size); + nrerror("SPACE allocation failure -> no memory"); + } + return pointer; +} + + +void nrerror(char *message) /* output message upon error */ +{ + fprintf(stderr, "\n%s\n", message); + exit(0); +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2ct.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2ct.o new file mode 100755 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100755 index 00000000..faa40f44 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/b2mt.pl @@ -0,0 +1,42 @@ +#!/usr/bin/perl -w +# -*-Perl-*- +# Last changed Time-stamp: <2005-03-09 19:38:25 ivo> +# produce Pauline's mountain representation from bracket notation +# use e.g. as RNAfold < foo.seq | b2mt | xmgr -pipe +# definition: h=number of base pairs enclosing base +use strict; +while (<>) { + print if (s/>/#/); + + next unless (/\.\.\./); + next if (/\[/); # don't process output from partition function + chop; + my @F=split(//,$_); + my $p=0; my $h=0; + foreach my $i (@F) { + $h-- if ($i eq ')'); + $p++; + printf("%4d %4d\n",$p,$h); + $h++ if ($i eq '('); # increase $h *after* printing + } + print "&\n"; +} + +=head1 NAME + +b2mt - produce coordinates for a mountain plot from bracket notation + +=head1 SYNOPSIS + + b2mt.pl < seq.fold > mountain.dat + +=head1 DESCRIPTION + +read a secondary structures in bracket notation as output by RNAfold, +and compute coordinates for a mountain plot as introduced by Pauline Hogeweg. +The output is suitable for graphing with xmgrace, e.g.: +C< RNAfold < foo.seq | b2mt.pl | xmgrace -pipe> + +=head1 AUTHOR + +Ivo L. Hofacker diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/cmount.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/cmount.pl new file mode 100755 index 00000000..4cec21d8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/cmount.pl @@ -0,0 +1,152 @@ +#!/usr/bin/perl -w +# -*-Perl-*- +# Last changed Time-stamp: <2005-11-07 13:31:34 ivo> +# Produce coloured Hogeweg mountain representation in PostScript. +# Input is a colour _dp.ps file from alidot or RNAalifold +# definition: mm[i],mp[i]=number of base pairs enclosing base i + +use strict; +use vars qw(@mm @mp @hue @sat @pair @pr); +sub usage { + die "Usage: $0 alidot.ps\n"; +} + +usage() if eof(); + +print "%!PS-Adobe-2.0 EPSF-1.2 +%%Title: Mount Ali +%%Creator: in hiding +%%BoundingBox: 66 209 518 686 +%%Pages: 1 +%%EndComments\n"; + + +print <) { + chomp; + if (/^% Subsequence from (\d+) to (\d+)/) { # get start and end + $from=$1; $to=$2; + } + if (/\/sequence \{ \((\S*)[\\\)]/) { + print "$_\n"; + $seq = $1; # empty for new version + while (!/\) \} def/) { # read until end of definition + $_ = <>; + print $_; + /(\S*)[\\\)]/; # ends either with `)' or `\' + $seq .= $1; + } + print "/len { sequence length } def\n"; + $length = length($seq); + next; + } + + next if /^%/; + next unless /[ul]box$/; + # Damn! alidot and alifold use different postscript macros. + # Try to recognize both + my ($h, $s, $blah, $i, $j, $p, $tok); + if (/ hsb /) { # alifold version + ($h, $s, $blah, $i, $j, $p, $tok) = split; + + } else { # alidot version + ($i, $j, $p, $h, $s, $tok) = split; + } + + if ($tok eq "lbox") { # only read lbox entries + $mp[$i+1]+=$p*$p; + $mp[$j] -=$p*$p; + $pair[$i] = $j; + $hue[$i] = $h; + $sat[$i] = $s; + $pr[$i] = $p*$p; + } +} +my $max=0; +$mp[0]=$mm[0]=0; +for (my $i=1; $i<=$length; $i++) { #find maximum for scaling + $mp[$i]+=$mp[$i-1]; + $max = $mp[$i] if ($mp[$i]>$max); + $mm[$i]+=$mm[$i-1]; + $max = $mp[$i] if ($mp[$i]>$max); +} + +# postscript scaleing etc +print "72 216 translate\n"; +print "/xs {72 6 mul len div} def /ys {72 6 mul $max div} def xs ys scale\n"; +print "0.03 setlinewidth +/Times-Roman findfont 1.8 scalefont setfont +0 1 len 1 sub { + dup + 0.8 add -0.5 moveto + sequence exch 1 getinterval + gsave 1 $max len div scale show grestore +} for\n\n"; + +print "/Times-Roman findfont 10 scalefont setfont +0.01 setlinewidth +len log 0.7 sub cvi 10 exch exp % grid spacing +gsave 0.5 0 translate +/temp 12 string def +0 exch len { + dup dup + 0 moveto + $max 1.03 mul lineto + cvi $from 1 sub add temp cvs centershow +} for +stroke +grestore\n"; + + +for (my $i=1; $i<=$length; $i++) { # print pairs as coloured trapezes + next unless ($pair[$i]); + print "$i $pair[$i] "; + printf "%6.4f %6.4f $hue[$i] $sat[$i] trapez\n", $mp[$i], $pr[$i] ; +} + +print "showpage\n"; + +=head1 NAME + +cmount.pl - produce a colored mountain plot of a consensus structure + +=head1 SYNOPSIS + + cmount.pl alidot.ps + +=head1 DESCRIPTION + +cmount.pl reads a color dot plot as produced by either C or C and writes a postscript colored mountain plot to +stdout. + +In the mountain plot a colored trapez with baseline from position i to +j represents the pair (i,j) in the consensus structure. The color of +the trapez encodes the sequence variation at that pair: Red marks +pairs with no sequence variation; ochre, green, turquoise, blue, and +violet mark pairs with 2,3,4,5,6 different tpyes of pairs, +respectively. + +=cut diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/coloraln.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/coloraln.pl new file mode 100755 index 00000000..3a87ccbd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/coloraln.pl @@ -0,0 +1,531 @@ +#!/usr/bin/perl -w + +use Getopt::Long; +use POSIX; +#use GD; +use strict; + +my $ssFile='alirna.ps'; +my $columnWidth=120; +my $formatT=0; +my $help=0; + +GetOptions ('-s:s' => \$ssFile, + '-c:i' => \$columnWidth, + '-t' => \$formatT, + "help"=>\$help, + "h"=>\$help, + ); + +if ($help){ + print "\ncoloraln.pl [-s structure.ps] < file.aln \n\n"; + print " -s ... RNAalifold consensus structure file (default: alirna.ps) \n"; + print " -c ... maximum number of columns in a block (default: 120)\n"; + print " -t ... print Ts (default: print Us)\n\n"; + exit(1); +} + +if (!-e $ssFile){ + print "No RNAalifold consensus secondary structure file found (use option -s with the correct filename).\n"; + exit(1); +} + +my $aln=readClustal(); + +my @ss=(); +for my $i (1..length($aln->[0]->{seq})){ + push @ss,'.'; +} + +my $consStruc=''; + +open(ALIRNA,"<$ssFile"); +my $pairsFlag=0; +my $sequenceFlag=0; +while (){ + $pairsFlag=1 if (/\/pairs/); + if ($pairsFlag and /\[(\d+) (\d+)\]/){ + $ss[$1-1]='('; + $ss[$2-1]=')'; + } + $pairsFlag=0 if ($pairsFlag and /def/); +} + +$consStruc=join('',@ss); + +for my $row (@$aln){ + $row->{seq}=uc($row->{seq}); + if ($formatT){ + $row->{seq}=~s/U/T/g; + } else { + $row->{seq}=~s/T/U/g; + } +} + + +my $consSeq=consensusSeq($aln); + +#print "$consSeq\n$consStruc\n"; + +plotAln($aln,$consSeq,$consStruc); + + + +###################################################################### +# +# consensusSeq(\@aln alnref) +# +# Returns consensus sequence of alignment +# +###################################################################### + +sub consensusSeq{ + + my @aln=@{$_[0]}; + my $out=''; + + for my $i (0..length($aln[0]->{seq})-1){ + + my %countHash=('A'=>0,'C'=>0,'G'=>0,'T'=>0,'U'=>0,'-'=>0); + #print %countHash,"\n"; + for my $j (0..$#aln){ + my $c=substr($aln[$j]->{seq},$i,1); + $countHash{$c}++; + } + #print %countHash,"\n"; + my $maxCount=0; + my $maxChar=''; + + for my $c ('A','C','G','T','U','-'){ + if ($countHash{$c}>=$maxCount){ + $maxChar=$c; + $maxCount=$countHash{$c}; + } + } + $out.=$maxChar; + } + return $out; +} + + +###################################################################### +# +# readClustal(filehandle) +# +# Reads Clustal W formatted alignment file and returns it in list of +# hash references with keys "name" and "seq" for the name and the sequence, +# resp. +# +###################################################################### + +sub readClustal{ +# my $fh=shift; + my @out=(); + my (%order, $order, %alignments); + while(<>) { + next if ( /^\s+$/ ); + my ($seqname, $aln_line) = ('', ''); + if( /^\s*(\S+)\s*\/\s*(\d+)-(\d+)\s+(\S+)\s*$/ ) { + # clustal 1.4 format + ($seqname,$aln_line) = ("$1/$2-$3",$4); + } elsif( /^(\S+)\s+([A-Z\-]+)\s*$/ ) { + ($seqname,$aln_line) = ($1,$2); + } else { + next; + } + if( !exists $order{$seqname} ) { + $order{$seqname} = $order++; + } + $alignments{$seqname} .= $aln_line; + } + + foreach my $name ( sort { $order{$a} <=> $order{$b} } keys %alignments ) { + if( $name =~ /(\S+):(\d+)-(\d+)/ ) { + (my $sname,my $start, my $end) = ($1,$2,$3); + } else { + (my $sname, my $start) = ($name,1); + my $str = $alignments{$name}; + $str =~ s/[^A-Za-z]//g; + my $end = length($str); + } + my $seq=$alignments{$name}; + push @out, {name=>$name,seq=>$seq}; + } + return [@out]; +} + +###################################################################### +# +# getPairs(\@aln alnref, $ss string) +# +# Evalutates the pairing of an alignment according to a given +# consensus secondary structure +# +# Returns list of all base pairs which is a hash with the following +# keys: +# +# open ... column in the alignment of the first base in the pair "(" +# close ... column in the alignment of the second base in the pair ")" +# all ... list of all basepairs in the different sequences in the alignment +# pairing ... list of all different pairing basepairs +# nonpairing ... list of all incompatible basepairs +# +###################################################################### + +sub getPairs{ + + my @inputAln=@{$_[0]}; + my $ss=$_[1]; + + # return nothing if there are no pairs + if (!($ss=~tr/(/(/)){ + return (); + } + + my @aln=(); + foreach my $row (@inputAln){ + my $seq=$row->{seq}; + $seq=uc($seq); + $seq=~s/T/U/g; + my @tmp=split(//,$seq); + push @aln,\@tmp; + } + my @ss=split(//,$ss); + + my @pairs=(); + my @stack=(); + + foreach my $column (0..$#ss){ + + my $currChar=$ss[$column]; + + if ($currChar eq '('){ + push @stack,$column; + } + + if ($currChar eq ')'){ + my $openedCol=pop @stack; + push @pairs,{open=>$openedCol,close=>$column}; + } + } + + @pairs=sort {$a->{open} <=> $b->{open}} @pairs; + + foreach my $i (0..$#pairs){ + #print "$i: $pairs[$i]->{open} - $pairs[$i]->{close}\n"; + + my @all=(); + my @pairing=(); + my @nonpairing=(); + + for my $j (0..$#aln){ + my $currPair=$aln[$j][$pairs[$i]->{open}].$aln[$j][$pairs[$i]->{close}]; + push @all,$currPair; + } + + for my $pair (@all){ + if (($pair eq 'AU') or + ($pair eq 'UA') or + ($pair eq 'GC') or + ($pair eq 'CG') or + ($pair eq 'UG') or + ($pair eq 'GU')){ + + push @pairing, $pair; + } elsif ($pair eq "--"){ + # do nothing + } else { + push @nonpairing,$pair; + } + } + + undef my %saw; + my @uniquePairing = grep(!$saw{$_}++, @pairing); + + $pairs[$i]->{all}=[@all]; + $pairs[$i]->{pairing}=[@uniquePairing]; + $pairs[$i]->{nonpairing}=[@nonpairing]; + } + + return @pairs; + +} + + +###################################################################### +# +# plotAln(\@aln ref-to-alignment, $consensus string, $ss string) +# +# Creates a image of the alignment with various annotations +# +# \@aln ... alignment in list of hash format +# $consensus ... consensus sequence +# $ss ... consensus secondary structure in dot bracket notation +# +# Returns png as string. +# +###################################################################### + +sub plotAln{ + + my @aln=@{$_[0]}; + my $consensus=$_[1]; + my $ss=$_[2]; + + my $ps=''; + + # Get important measures + (my $fontWidth, my $fontHeight) = (6,6); + + my $length=length($aln[0]->{seq}); + my $maxName=0; + foreach my $row (@aln){ + $maxName=length($row->{name}) if (length($row->{name})>$maxName); + } + + # Custom Sizes + my $lineStep=$fontHeight+2; # distance between lines + my $blockStep=3.5*$fontHeight; # distance between blocks + my $consStep=$fontHeight*0.5; # distance between alignment and conservation curve + my $ssStep=2; + my $nameStep=3*$fontWidth; # distance between names and sequences + my $maxConsBar=2.5*$fontHeight; # Height of conservation curve + my $startY=2; # "y origin" + my $namesX=$fontWidth; # "x origin" + my $seqsX=$namesX+$maxName*$fontWidth+$nameStep; # y-coord. where sequences start + + # Calculate width and height + + my $tmpColumns=$columnWidth; + + $tmpColumns=$length if ($length<$columnWidth); + + my $imageWidth=$namesX+($maxName+$tmpColumns)*$fontWidth+$nameStep+$fontWidth; + my $imageHeight=$startY+(ceil($length/$columnWidth))*((@aln+1)*$lineStep+$blockStep+$consStep+$ssStep); + + + + my $white="1 1 1"; + my $black="0 0 0" ; + my $grey="1 1 1"; + + my $red="0.0 1"; + my $ocre="0.16 1"; + my $green="0.32 1"; + my $turq="0.48 1"; + my $blue="0.65 1"; + my $violet="0.81 1"; + + + my $red1="0.0 0.6"; + my $ocre1="0.16 0.6"; + my $green1="0.32 0.6"; + my $turq1="0.48 0.6"; + my $blue1="0.65 0.6"; + my $violet1="0.81 0.6"; + + my $red2="0.0 0.2"; + my $ocre2="0.16 0.2"; + my $green2="0.32 0.2"; + my $turq2="0.48 0.2"; + my $blue2="0.65 0.2"; + my $violet2="0.81 0.2"; + + + my @colorMatrix=([$red,$red1,$red2], + [$ocre,$ocre1,$ocre2], + [$green,$green1,$green2], + [$turq,$turq1,$turq2], + [$blue,$blue1,$blue2], + [$violet,$violet1,$violet2]); + + my @pairs=getPairs(\@aln,$ss); + + foreach my $pair (@pairs){ + + foreach my $column ($pair->{open},$pair->{close}){ + my $block=ceil(($column+1)/$columnWidth); + my $effCol=$column-($block-1)*$columnWidth; + my $x=$seqsX+$effCol*$fontWidth; + + foreach my $row (0..$#aln){ + + my $pairing=@{$pair->{pairing}}; + my $nonpairing=@{$pair->{nonpairing}}; + + my $color; + + if ($nonpairing <=2){ + $color=$colorMatrix[$pairing-1][$nonpairing]; + + if (($pair->{all}->[$row] eq 'AU') or + ($pair->{all}->[$row] eq 'UA') or + ($pair->{all}->[$row] eq 'GC') or + ($pair->{all}->[$row] eq 'CG') or + ($pair->{all}->[$row] eq 'GU') or + ($pair->{all}->[$row] eq 'UG')){ + + my $y=$startY+($block-1)*($lineStep*(@aln+1)+$blockStep+$consStep)+$ssStep*($block)+($row+1)*$lineStep; + + my $xtmp=$x+$fontWidth; + my $ytmp1=$y-1; + my $ytmp2=$y+$fontHeight+1; + $ps.="$x $ytmp1 $xtmp $ytmp2 $color box\n"; + } + } + } + } + } + # Calculate conservation scores as (M+1)/(N+1), where M is the + # number of matches to the consensus and N is the number of + # sequences in the alignment + + my @conservation=(); # each column one score + + for my $column (0..$length-1){ + + my $consChar=substr($consensus,$column,1); + + # if consensus is gap, score=0 + if ($consChar eq "-" or $consChar eq "_"){ + push @conservation, 0; + next; + } + + my $match=0; + for my $row (0..$#aln){ + my $currChar=substr($aln[$row]->{seq},$column,1); + $match++ if ($currChar eq $consChar); + } + + my $score=($match-1)/(@aln-1); + push @conservation,$score; + } + + # Draw the alignments in chunks + my $currY=$startY; + my $currPos=0; + + while ($currPos<$length){ + + # secondary structure in first line + #$out->string($font,$seqsX,$currY,substr($ss,$currPos,$columnWidth),$black); + my $tmpSeq=substr($ss,$currPos,$columnWidth); + $tmpSeq=~s/\(/\\\(/g; + $tmpSeq=~s/\)/\\\)/g; + $ps.="($tmpSeq) $seqsX $currY string\n"; + $currY+=$lineStep+$ssStep; + + # sequences labeled only with the organism-specifier + foreach my $row (@aln){ + #$out->string($font,$namesX,$currY,$row->{name},$black); + $ps.="($row->{name}) $namesX $currY string\n"; + #$out->string($font,$seqsX,$currY,substr($row->{seq},$currPos,$columnWidth),$black); + my $tmpSeq=substr($row->{seq},$currPos,$columnWidth); + $ps.="($tmpSeq) $seqsX $currY string\n"; + $currY+=$lineStep; + } + + # conservation curve + $currY+=$consStep; + $ps .= "0.6 setgray\n"; + for my $col ($currPos..$currPos+$columnWidth-1){ + my $score=shift @conservation; + last if (!defined $score); + my $barHeight=$maxConsBar*$score; + $barHeight=1 if ($barHeight==0); + my $x=$seqsX+($col-($columnWidth*int($currPos/$columnWidth)))*$fontWidth; + # $out->filledRectangle($x,$currY+$maxConsBar-$barHeight,$x+$fontWidth,$currY+$maxConsBar,$grey); + my $ytmp1=$currY+$maxConsBar-$barHeight; + my $xtmp2=$x+$fontWidth; + my $ytmp2=$currY+$maxConsBar; + $ps .= "$x $ytmp1 $xtmp2 $ytmp2 box2\n"; + } + $currY+=$blockStep; + $currPos+=$columnWidth; + } + + my $BB="0 0 $imageWidth $imageHeight"; + + while (){ + s/!BB!/$BB/; + s/!HEIGHT!/$imageHeight/; + print; + } + print $ps; + print "showpage\n"; +} + +=head1 NAME + +coloraln.pl - colorize an alignment with consensus structure + +=head1 SYNOPSIS + + coloraln.pl [-s structure.ps] file.aln + +=head1 DESCRIPTION + +colorrna.pl reads an alignment in CLUSTAL format, and a consensus +secondary structure (which it extracts from a postscript secondary +structure plot). It produces a postscript figure of the alignment, in +which compensatory mutation supporting the consensus structure are +marked by color. The color scheme is the same employed by RNAalifold +and alidot: Red marks pairs with no sequence variation; ochre, green, +turquoise, blue, and violet mark pairs with 2,3,4,5,6 different tpyes +of pairs, respectively. + +=head1 OPTIONS + +=over 4 + +=item B<-s> I + +read I to extract the consensus structure (default: C) + +=item B<-c> I + +break alignments into blocks of at most I columns, (default: 120) + +=item B<-t> + +suppress conversion of C to C, i.e. do not convert DNA to +RNA, (default: convert to C) + +=back + +=cut + + +__DATA__ +%!PS-Adobe-3.0 EPSF-3.0 +%%BoundingBox: !BB! +%%EndComments + +% draws Vienna RNA like colored boxes +/box { % x1 y1 x2 y2 hue saturation + gsave + dup 0.3 mul 1 exch sub sethsbcolor + exch 3 index sub exch 2 index sub rectfill + grestore +} def + +% draws a box in current color +/box2 { % x1 y1 x2 y2 + exch 3 index sub exch 2 index sub rectfill +} def + +/string { % (Text) x y + 6 add + moveto + show +} def + +0 !HEIGHT! translate +1 -1 scale +/Courier findfont +[10 0 0 -10 0 0] makefont setfont + +%100 100 106 110 0.5 0.5 1 box +%(A) 100 100 string +%(This is a string) 200 200 string diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/colorrna.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/colorrna.pl new file mode 100755 index 00000000..748a9550 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/colorrna.pl @@ -0,0 +1,111 @@ +#!/usr/bin/perl -w +# -*-CPerl-*- +# Last changed Time-stamp: <2005-11-07 12:08:38 ivo> +# $Id: colorrna.pl,v 1.1 2005/11/07 12:42:27 ivo Exp $ +# colorize a secondary structure plot with reliability annotation +# from positional entropy +use strict; +use Getopt::Std; +$main::VERSION = 1.0; +$Getopt::Std::STANDARD_HELP_VERSION=1; + +our $opt_p; +getopts('p'); + +sub HELP_MESSAGE { + print STDERR "\nusage: $0 FOO_ss.ps FOO_dp.ps > FOO_css.ps\n"; + print STDERR "For more details run\n\tperldoc -F $0\n"; +} + +HELP_MESSAGE() unless $#ARGV >0; +my $macro_seen= 0; +my %mfe = (); # hash of mfe pairs +my @ss_ps = ('',''); # head and tail of the ss.ps file + +my $n = swallow_ss_ps(); # read ss plot +my %hsb = read_dp(); # read dot plot and compute entropies + +print $ss_ps[0]; # print head +if (!$macro_seen) { + print <<_E_O_F_ +/hsb { + dup 0.3 mul 1 exch sub sethsbcolor +} bind def +/colorpair { % i j hue sat colorpair + % draw basepair i,j in color + % 1 index 0.00 ne { + gsave + newpath + hsb + fsize setlinewidth + 1 sub coor exch get aload pop moveto + 1 sub coor exch get aload pop lineto + stroke + grestore + % } if +} bind def +_E_O_F_ +} +foreach my $k (keys %hsb) { + my ($i,$j) = split($;,$k); + print "$i $j ", $hsb{$k}->[0], " ", $hsb{$k}->[1]," colorpair\n"; +} +print $ss_ps[1]; # print main part +print $ss_ps[2]; # print showpage etc + +sub swallow_ss_ps { + # read the secondary structure plot + my $length=0; + my $tail=0; + while (<>) { + $macro_seen=1 if /colorpair/; + $length ++ if /^\/coor/ .. /^\] def/; + if (/^\/pairs/ .. /^\] def/) { + $mfe{$1,$2}=1 if /(\d+)\s+(\d+)/; + } + next if /\d gmark$/; + $tail++ if /^drawpairs/; + s/^drawpairs/% drawpairs/; + $tail++ if /^showpage/; + $ss_ps[$tail] .= $_; + last if eof; + } + return $length-2; +} + +sub read_dp { + # read dot plot and extract hsb values + my %hsb; + while (<>) { + next unless /lbox$/; + my @F = split; + $hsb{$F[3],$F[4]} = [$F[0], $F[1]]; + } + return %hsb; +} + +=head1 NAME + +colorrna - colorize an alirna.ps file + +=head1 SYNOPSIS + + colorrna.pl alirna.ps alidot.ps > colorRNA.ps + +=head1 DESCRIPTION + +colorrna reads an RNA secondary structure plot and a dot plot +containing pair probabilities and covariance annotation as, produced +by C, and writes a new secondary structure plot with +color annotated seqence annotation to stdout. The color annotation +is taken directly from the color dot plot file. + +=head1 AUTHOR + +Ivo L. Hofacker +Stefan Washietl + +=cut + +# End of file + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/ct2b.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/ct2b.pl new file mode 100755 index 00000000..1a5ee530 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/ct2b.pl @@ -0,0 +1,27 @@ +#!/usr/bin/perl +# -*-Perl-*- +# Last changed Time-stamp: <1999-09-29 13:24:23 ivo> +# produce dot bracket notation of an RNA secondary structure from +# Zuker's .ct file + +while (<>) { + @F = split; + if ((/ = /) && ($#F!=5)) { + if (defined($seq)) { + print "$seq\n" unless ($seq eq $oldseq); + $oldseq = $seq; + print "$s ($E)\n"; + } + $E = $F[3]; + $s = $seq = ""; + next; + } + $seq .= $F[1]; + if ($F[4]==0) {$s .= "."; next} + $s .= "(" if ($F[0]<$F[4]); + $s .= ")" if ($F[0]>$F[4]); +} +print "$seq\n" unless ($seq eq $oldseq); +print "$s ($E)\n" if defined($s); + +# End of file diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/dpzoom.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/dpzoom.pl new file mode 100755 index 00000000..2fd0d2d5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/dpzoom.pl @@ -0,0 +1,46 @@ +#!/usr/bin/perl -w +# zoom into a PostScript dot plot produced by RNAfold, RNAalifold or alidot +# Last changed Time-stamp: <2003-03-24 12:47:26 ivo> +sub usage { + die "Usage: $0 [-f first] [-l last] [dp_file]\n"; +} + +$from=1; +$to = -1; +# parse command line +while ($_ = shift) { + /^-[\?h]/ && usage(); + /^-f$/ && ($from = shift, next ); + /^-l$/ && ($to = shift, next ); + unshift (@ARGV, $_); + last; +} + +usage() if eof(); + +while (<>) { + if (/\/sequence \{ \((\S*)[\\\)]/) { + $seq = $1; # empty for new version + while (!/\) \} def/) { # read until end of definition + $_ = <>; + /(\S*)[\\\)]/; # ends either with `)' or `\' + $seq .= $1; + } + if ($to>$from) { $seq=substr($seq,$from-1,$to-$from+1) } + else { $seq=substr($seq,$from-1) } + print "% Subsequence from $from to $to\n"; + print "/sequence { (\\\n"; + for ($p=0; $p$to)&&($to>0))); + $i -= ($from-1); + $j -= ($from-1); + printf "%d %d %s\n", $i, $j, $3; + } + else {print} +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/mountain.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/mountain.pl new file mode 100755 index 00000000..d6c5b2d9 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/mountain.pl @@ -0,0 +1,106 @@ +#!/usr/bin/perl -w +# -*-Perl-*- +# Last changed Time-stamp: <2004-07-19 10:36:39 ivo> +# produce Pauline Hogeweg's mountain representation *_dp.ps files +# writes 3 sets of x y data separated by a "&" +# the first two sets are mountain representations from base pair probabilities +# and mfe structure, respectively. +# definition: mm[i],mp[i] = (mean) number of base pairs enclosing base i +# third set a measure of well-definedness: the entropy of the pair probs of +# base i, sp[i] = -Sum p_i * ln(p_i). Well-defined regions have low entropy. +# +# use e.g. as mountain.pl dot.ps | xmgrace -pipe + +use strict; +our (@mm, @mp, @pp, @sp, @p0, $i, $max, $length, $do_png); # perl5 only + +my $sep = "&"; # xmgr uses & to separate data sets + +if (@ARGV && ($ARGV[0] eq '-png')) { + eval "use Chart::Lines"; + die($@, + "\nCould not load the Chart::Lines module required with -png option\n") + if $@; + $do_png=1; + shift; +} + + +while (<>) { + my ($seq,$i,$j,$p,$id); + chop; + if (/\/sequence \{ \((\S*)[\\\)]/) { + $seq = $1; # empty for new version + while (!/\) \} def/) { # read until end of definition + $_ = <>; + /(\S*)[\\\)]/; # ends either with `)' or `\' + $seq .= $1; + } + $length = length($seq); + next; + } + + next unless /box$/; + ($i, $j, $p, $id) = split; + if ($id eq "ubox") { + $p *= $p; # square it to probability + $mp[$i+1] += $p; + $mp[$j] -= $p; + my $ss = $p*log($p); + $sp[$i] += $ss; + $sp[$j] += $ss; + $pp[$i] += $p; + $pp[$j] += $p; + } + if ($id eq "lbox") { + $mm[$i+1]++; + $mm[$j]--; + } +} +$mp[0] = $mm[0] = $max = 0; +for ($i=1; $i<=$length; $i++) { + no warnings; + $mp[$i]+=$mp[$i-1]; + $max = $mp[$i] if ($mp[$i]>$max); + $mm[$i]+=$mm[$i-1]; + $max = $mp[$i] if ($mp[$i]>$max); + $sp[$i] += (1-$pp[$i])*log(1-$pp[$i]); +} + +if ($do_png) { + my $width = 800; + my $height = 600; + + # FIXME: legend_lables when doing mfe only + my $skip = 10**(int (log($length)/log(10.) - 0.5)); + my $obj = Chart::Lines->new( $width, $height ); + $obj->set ('title' => $ARGV, + 'x_label' => 'Position', + 'y_label' => 'Height', + 'min_val' => 0, + 'precision' => 0, + 'legend_labels' => ['mfe', 'pf'], + 'skip_x_ticks' => $skip); + + $obj->add_dataset ((0..$length)); + + $obj->add_dataset (@mp); + $obj->add_dataset (@mm); + $obj->png("mountain.png"); + +} else { + # print the results for plotting + for ($i=1; $i<=$length; $i++) { + printf("%4d %7.5g\n", $i, $mp[$i]); + } + print "$sep\n"; + + for ($i=1; $i<=$length; $i++) { + printf("%4d %4d\n", $i, $mm[$i]); + } + print "&\n"; + my $log2 = log(2); + for ($i=1; $i<=$length; $i++) { + printf("%4d %7.5g\n", $i, -$sp[$i]/$log2); + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/popt b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/popt new file mode 100755 index 0000000000000000000000000000000000000000..8a8ecea419ed06a0bd4c675acf0e106fd9aa8818 GIT binary patch literal 16687 zcmcJ03w%^XmUrF0-Q=1ybcX<<@@OSEghxUUlmt{>4aDIkdHBSpNxIXmNq6iAf(sgK zPW<+di0jNR`thwGj?1_>HimJcvdAby_W!SYZ*miz zot^J-lj^E}ol~byovKs!R^7Vydl$`D6h)YqO{jv%{g7Roig@8H~A_N1=3%5>}c~60cunYwn z5LhqiHbiaUZv%~?1DJty*1<3i{NqqJg9n(wq}}*oq5<%0ms!57DZHwzsbNx6IFejb z8jqGv(aWN0sr!N@wX!VrV4&WG2$vdZL}DnyaD;q>ixHd%gAvSYkdZ($#4v=55H2zD z`bVsz|HZaQdl&@T+`Q0qc@^N-g+SZqAyEH;2-HvDu6z+(^- zKa6k^xYEGW5uXA6%D~$Y+aI)R6$YMw;4ggOz=sOS}0shp$A0R#nyvM+eh>u#@_X6pUn(ZAVlE7yy<=H>x z&z|5 zM19B~6T!wnA})a9qTb)s6s;G*mRLBF2#WedxH%x=iCDcqfv6!I5wU>I;;UNfL%Dhp zkJtMnK~e*;mVq_YA{>o~z?yJEun=pN2`SH)j0YOPO|1+SoBgN; zbv6ZLR3Czdu|Pm9SX4D zo%wUdaP(&wLxblT!_jv#h9mA~3?*M-3@2=7jDdE5F`V>u#+VS^WQ<9pHvM7hw3f?4 z#oS5$`~kub?-$+E)_|jX>^l6iiQQw_k`R-pPITiM%NB)5JJlgETNa{uPPI$S7KS)I zoqAqkwlw4+-Yzj)92!U5CNWzcV*i|Km6#R?(fv=gNK8wFW)ZKHm=*~wBwi*lEfZQs zJWFC)D0DONWQl31&`M&D#I#t54LaqPn3fB*5DSTE!O$Awt_#Q*OG}1YiBCvOi-tB6 zcSuajhT4eRC8mW#j}t!+jJW42|NR~5-=Evs1`S_a<@Y52LZF4TehVQviSI@8vM zeyPr}#BCe)Uo%RGWtr6NK%3eVw(gG1it~r}xAk0lAGTim9%>W`XXl7iyZxsRKz`k-s$?=h&-Q;TymV1!wuEdgWN zdwNd}jZQBrwu6|SSFGiJ00yLg34W1#79it2O@15m4`uC}IHfaVpcL?4=cx3#lCJDB z#r0fAx?^u{w6ZVbeebO=vo)1UddTzhD=yske%7aC7ua0S?N9I9`|)U{+nc7^|+XZ!<>6&8grA{`Xrr4f) z|4&l)^#0r#q&6K-ypr+e%FnX0GE4?(@5zb_hrCBAe7(OdQ+v|&>WEmy=l4y^)V`Oo z|6`{1M9IX`LmyPMLX%oKHywvkiEm-VQM24qh>$9k^ixUq zx^z;bme5rydTIn}$-Vq#KV=U<*&|fqS8$Nd7pd%?F!h8__1LNwrNAe)f$wMZDJV;O zWxeMy?Xx*4aAa!F(}M;C(?d_d$XUBB_|p$)ZDcx?eaJoubl7aBY@Y_PWX{4VeLgEcp7A;}>!n>Xve?P&0)@rCkHK5f)l zG*_Q5a-Fd3vGt$4xA>wvU=y@zuItAGBX5 zQU@lcyQE*C{>);nuKX-)<8-}Pxbf}8M5{erFRB~c6PHZi=lX8@Y|vdVwkrqcZhSlW zJDuycbQfBkU2V=^vOSQt;q(Yjm9VJxDj#Ih>tMHe#aeb#4$Wb+{>M2EMAt^%w)EVW zIh|nEkp|9_}=VK{|kQCnUVLe@@@{P5u9XThrj)TVtB4Fetqw`(QkcOvTqKj!tZgi@SetWdC1!Z8;Oc{)(3R^mmmM7yf^jC zzl*i(h}&Ghv{$6gl_dQ4SL5b-aq8T-#9*Bto->XPIRqlh+h?rLxt?fO4lP-GC{x?D z`DkYG=?m?f?fG-kwOydCdlHj12)Ho_q*4b)$T5>TSDM^4x3isQfwen#S?t69*V{J} z?K|i_I_{wNSm{CUyCrPvKb~bn-ptNxl{R@54l!f>n`v*yAukt0V*Rqr;v+A!L77?& zgEl|A5O;=-?9{wAW18DtS6f^A#VKi@l6_hG@{+yj*VAvgUYzGRiV^PY}YU66=BX8mwcBF{-x{HbFghNJz`l8+kMA+?x&l&lM6Dnr#T9S!gv{P&g=!f zKS9ebfPUwK7`v|yxfdO`rWVr}>rUHmMGBJVoVu4c3*)AC11D zOEhWP+toP%(~4`Cz0S4ESsko+JuwsFz5HWo`>U0Aww^iP08YW_x{ng>2UV$?qorZy92k~ad?0FtRW}; 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+ exit(EXIT_FAILURE); +} + +/*-------------------------------------------------------------------------*/ + +int main (int argc, char *argv[]) +{ + char *line, *sequence, *structure; + int i, j, length; + float energy; + + short *ptable; + char *pair_seen; + int *iindx; + + if (argc>1) help(); + + line = get_line (stdin); + if (*line=='>') { + free (line); + line = get_line (stdin); + } + + /* read the sequence */ + sequence = (char *) space (sizeof (char) * (strlen(line)+1)); + (void) sscanf(line, "%s", sequence); + free (line); + length = (int) strlen(sequence); + + iindx = (int *) space(sizeof(int)*(length+1)); + for (i=1; i<=length; i++) + iindx[i] = ((length+1-i)*(length-i))/2 +length+1; + pair_seen = (char *) space(((length+1)*(length+2))/2 * sizeof(char)); + + structure = (char *) space (sizeof (char) * (length+1)); + + /* get of suboptimal structures */ + + while ((line = get_line (stdin))) { + int r, popt; + + r = sscanf(line, "%s %f", structure, &energy); + free(line); + if (r==0) continue; + ptable = make_pair_table(structure); + + popt = 0; + for (i = 0; i < length; i++) { + if ((j=ptable[i])>i) + if (pair_seen[iindx[i]-j]==0) { + pair_seen[iindx[i]-j]=(char) 1; + if (popt==0) { + printf("%s %6.2f", structure, energy); + popt = 1; + } + printf(" (%d,%d)", i,j); + } + } + if (popt==1) printf("\n"); + free(ptable); + } + free(sequence); free(structure); free(iindx); free(pair_seen); + + return 0; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/popt.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/popt.o new file mode 100755 index 0000000000000000000000000000000000000000..a5c90edf2a5d93b893bc6c758217261fb73d0c63 GIT binary patch literal 5708 zcma)AYiu0V6~1?7)-$mkukE!V0f%g`4RJ`;I5Cl9Lf&h~svBCc&7*0S_3qeSvYy?} z%$lSG66&O7F($YVAwj92YKz1}(2`Q6M8!axs6uT+%a2rqM~x&V9|@-5>Am;+!+TaHg^nW9&zjo~B*Ea<-UV;F}8UFaGt0f$PW5 zt{i{o-1yn*@jDD2KD`_t|wWc$l&CJXk=-5y^9zOU1JQv$N(I#J4jGsL!Y6eQyz4-o8e)82%W(NZvou|4#UY27BG#@4RZF|MZ0Rvx)w zif)s3LTg$8D%{_X)b>3;e#a?ZsE54Vmlr>h@xyr2)f zE7#K|Jcbp9eTAaYSh4Fo!d9cs{|V7yJj%zU*OlL+&JAS+iFAb;KuGJFmno-77*aEq z%e0VULuiDQJ_4P#71Ivq@K!cZHKbLc8}0r9l6byD+I>V+$az`Wa==}1_+2HYKLWYB zfL}}MMy4A?tN7i5YC54BmekM}p`ltWX{CNQ(Hcps^$Xxqt(CM+A0Zl%bdlaouIeOh z&>tgOFKJZ2nT#)#v`J5q=S7k(*DoWwSkjgHZ^-y!J_4!Ic%@!Xu9k31(02U*(WNq@ z4!xI*8zo(@zd+h%o(3q5oAhUiw(vEAZqwf-;}v|fpj~Z!7j(BOZa@uX`&%G?Q@_UFK^`^~WA*~IzA?RbKl^);VS3n34`MapIO2*3F-ovplaO0aZz4Y_I(t8nU;FlEJ? z9}v2owPQdk)i&cBMGx19cagmy%G8Z4@-R#~ArjjyqzOL`xQ4y49Zf?TwX1swFJ8~< zKLjfG(a3UMznjQmkFe*7u$#$_e_BEmxxBZv4SVn1*wORcdX19oyPWSzC3WkxY~H`2IHu@ z*x0XHM#^}tW97j1^~;}JVRt@$e*07E9-~{W=r_J^%qS~sRrev|K6TeG4yd;p>y9dw z2)5Z_%}%s=h((t-r&l(oTLfJjTRp_`s}N#lG?|SKWwNemN8Mc1DGWjw%@y2y!Hq== zPIB1nEWd8YW~o@^MAt_h^J~$4QA#jM!B^wKM`MOFzR#%Cw7ZcgZ5zMP6l|_C4k=p} zhPuW>-_*XPvJ0UUIkRa@6fMlrWX2LLsHvwC$C{A&hb9p^&YnOQpWwN~GZZ$7L~dv( z;j%=}wF%oyrW1MBW{K1Y`As+@Iolm93^6A&Y?M zdc)y}F`&VS&S{7#EtpoyWQlApwOhuznk7baSl#5qNsgJ`n3Oz<6riIfa^SmqdgCmS z&pE7hBsXfdB2L$IzTVnxS{bu-OU7y)$e5Ou#EL4_R<*^}w)VT3EJnx6%_*fNW=c$- zH$7uwIQ$Wky9@(A?2a&Do3PA17(%jG+a6pGVn%0kq2Tk$jGb^y6QiHVC(~^nAnk%x zaLn{-mb8b*uxTw*Y-exolBwN=yf+j>*<8{kqZB5?E~MOo?TwZ<;-W*=y>)A6bUD^q zi(G0f=Ik9s7C_hbaKx|KW;W(h{IPV>O|saa)dJb(5S`XRDQ8OsW7X~ee&|#^Iq@A>eN#yl7m!S(5vvRH(Lw2hi7bC-B zsodzOi9PcFm!&YpUS_yfiLwdr;D)F3h04Wv=mzbVW4OjHLPI)Bs68DQ2A*cgn~5s>_m-2sUJQSODE_j}XhWJhHmo?v`Uh>zx!;-ed~AKw(}FD_#9!%+Mc^tnVg2ngu284c{^kj#nKU;iV4J3i(#*V>`?vZ}+?Fa+m zuzQi@NeC$y@>4Bts%eo{(SCZP_D5LXM8!~+RngzHts~YV-{TTQ3g89+>>$9*F|_Z zhV@dQg2ABp6$~Sti%LCXU8Kj}8X%6nm?FesLDxgF+fN9)X^F2${0or$zDFE>7hoZh zpIRXKX&{83RfJgV^mB{!w-aB?*mnpK++&2Wdy@3l(L*ikH4@&%@#Ggu>miPyWZ%X_?;%5>o zXnfG$MG{*ic1Y}&I3UrK=t>-y_-%=gN_Cl;T({@d}A+ zC2o+|EAeKDk4Sui5YN*RpOf-mOZ=n6wb2DPb5AoahS#%_F}!@IHdE1xL99!`RK2&{{Y#MxV!)W literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/relplot.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/relplot.pl new file mode 100755 index 00000000..94811753 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/relplot.pl @@ -0,0 +1,184 @@ +#!/usr/bin/perl -w +# -*-CPerl-*- +# Last changed Time-stamp: <2005-03-09 19:45:55 ivo> +# $Id: relplot.pl,v 1.7 2005/11/07 12:40:46 ivo Exp $ +# colorize a secondary structure plot with reliability annotation +# from positional entropy +use strict; +use Getopt::Std; +$main::VERSION = 1.3; +$Getopt::Std::STANDARD_HELP_VERSION=1; + +our $opt_p; +getopts('p'); + +sub HELP_MESSAGE { + print STDERR "\nusage: $0 [-p] FOO_ss.ps FOO_dp.ps > FOO_rss.ps\n"; + print STDERR "For more details run\n\tperldoc -F $0\n"; +} + +HELP_MESSAGE() unless $#ARGV >0; +my $macro_seen= 0; +my %mfe = (); # hash of mfe pairs +my @ss_ps = ('',''); # head and tail of the ss.ps file + +my $n = swallow_ss_ps(); # read ss plot +my @sp = posent(); # read dot plot and compute entropies +my $Smax = $opt_p ? 1 : 0; +if (!$opt_p) { + foreach (@sp) { + $Smax = $_ if $_>$Smax; + } + $Smax = ($Smax>0.2) ? sprintf("%3.1f", $Smax) : 0.2 ; + +} +print $ss_ps[0]; # print head +if (!$macro_seen) { + print <<_E_O_F_ +/range 0.8 def +/drawreliability { + /Smax $Smax def + 0 + coor { + aload pop + S 3 index get + Smax div range mul + invert {range exch sub} if + 1 1 sethsbcolor + newpath + fsize 2 div 0 360 arc + fill + 1 add + } forall +} bind def +/colorbar { % xloc yloc colorbar -> [] + /STR 8 string def + gsave + xmin xmax add size sub 2 div + ymin ymax add size sub 2 div translate + size dup scale + translate + 0.015 dup scale + /tics 64 def + gsave + 10 tics div 1 scale + 0 1 tics + { + dup 0 moveto 0.5 add + tics div range mul + invert {range exch sub} if + 1 1 sethsbcolor + 1 0 rlineto 0 1 rlineto -1 0 rlineto closepath fill + } for + grestore + 0 setgray + -0.1 1.01 moveto (0) gsave 0.1 dup scale show grestore + 10 1.01 moveto Smax STR cvs + gsave 0.1 dup scale dup stringwidth pop -2 div 0 rmoveto show grestore + grestore +} bind def +_E_O_F_ +} +print "/S [\n"; +foreach (@sp) { + printf " %7.5f\n", $_; +} +print "] def\n\n"; +print "/invert ", $opt_p ? 'true' : 'false', " def\n"; +print "drawreliability\n"; +print "0.1 0.1 colorbar\n"; +print $ss_ps[1]; # print tail + +sub swallow_ss_ps { + # read the secondary structure plot + my $length=0; + my $tail=0; + while (<>) { + $macro_seen=1 if /drawreliability /; + $length ++ if /^\/coor/ .. /^\] def/; + if (/^\/pairs/ .. /^\] def/) { + $mfe{$1,$2}=1 if /(\d+)\s+(\d+)/; + } + $tail=1 if /^drawoutline/; + $ss_ps[$tail] .= $_; + last if eof; + } + return $length-2; +} + +sub posent { + # compute positional entropy from pair probs in the dot plot file + # or, with $opt_p, find pair probs corresponding to mfe pairs + my @pp; + my @sp; + while (<>) { + my ($i, $j, $p, $id) = split; + next unless defined $id && $id eq 'ubox'; + $p *= $p; + if ($opt_p) { + $sp[$i] = $sp[$j] = $p if exists $mfe{$i,$j}; + } else { + my $ss = $p*log($p); + $sp[$i] += $ss; + $sp[$j] += $ss; + } + $pp[$i] += $p; + $pp[$j] += $p; + } + my $log2 = log(2); + for my $i (1..$n) { + no warnings; # $p[$i] may be undef + if ($opt_p) { + $sp[$i] = 1-$pp[$i] if !defined $sp[$i]; + } else { + $sp[$i] += (1-$pp[$i])*log(1-$pp[$i]); + $sp[$i] /= -$log2; + } + } + shift @sp; # get rid of [0] entry + return @sp; +} + +=head1 NAME + +relplot - annotate a secdonary structure plot with reliability information + +=head1 SYNOPSIS + + relplot [-p] file_ss.ps file_dp.ps > file_rss.ps + +=head1 DESCRIPTION + +relplot reads an RNA secondary structure plot and a dot plot +containing pair probabilities, as produces by C, and +writes a new secondary structure with reliability annotation to +stdout. The anotation is used to colorize the plot and can use either +"positional entropy" (default), or pair probabilities (with -p). + +Positional entropies are computed from the pair probabilities as +C. Low entropy regions have little +structural flexibility and the reliability of the predicted structure +is high. High entropy implies many structural alternatives. While +these alternatives may be functionally important, they make structure +prediction more difficult and thus less reliable. + +If the -p switch is given, the script colors base pairs by their pair +probability, unpaired bases use the probability of being unpaired. + +Entropy (repsectively probability) is encoded as color hue, ranging +from red for low entropy, well-defined regions, (high probability +pairs) via yellow and green to blue and violet for regions with very +high entropy (low probability). + +You may have to manually move the color legend to a convenient +position. Just edit the postscript file and change the two numbers in the +line reading C<0.1 0.1 colobar>. Or delete the line to remove the legend. + +=head1 AUTHOR + +Ivo L. Hofacker + +=cut + +# End of file + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/rotate_ss.pl b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/rotate_ss.pl new file mode 100755 index 00000000..7e7f60ed --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Utils/rotate_ss.pl @@ -0,0 +1,138 @@ +#!/usr/bin/perl -w +# -*-Perl-*- +# Last changed Time-stamp: <2004-08-09 16:50:14 ivo> +# $Id: rotate_ss.pl,v 1.3 2004/08/10 08:54:05 ivo Exp $ + +use Getopt::Long; +use strict; +use vars qw/$ss_ps $opt_a $opt_m/; +use constant PI => 3.14159265; + +my $ss_ps = { Header => [], + Coords => [], + BPairs => [], + Tailer => [] }; +$opt_a = 0; +usage() unless GetOptions("a=i" => \$opt_a, "m"); + +swallow_ss_ps(); +my $ar = to_Array($ss_ps->{Coords}); +my $mp = get_Midpt($ar); +$ar = flip_Array($mp, $ar) if $opt_m; +$ar = rot_Array($mp, $ar) if $opt_a; +print_ss_ps($ar); + +#--- +sub usage { + printf STDERR "\nusage: $0 [-a ANGLE] [-m] FOO_ss.ps > BAR_ss.ps\n"; + exit(1); +} + +#--- +sub swallow_ss_ps { + local $_; + my $toggle = 0; + + while (<>) { + $toggle = 1 if m/^\/coor/; + push @{$ss_ps->{Header}}, $_ if $toggle == 0; + push @{$ss_ps->{Coords}}, $_ if $toggle == 1; + push @{$ss_ps->{BPairs}}, $_ if $toggle == 2; + push @{$ss_ps->{Tailer}}, $_ if $toggle > 2; + $toggle++ if m/\]\s+def/; + } +} + +#--- +sub to_Array { + my $aref = shift; + return [ map {chomp; s/\[//; s/\]//; [split] } @$aref[$[+1 .. $#$aref-1] ]; +} + +#--- +sub get_Midpt { + local $_; + my $aref = shift; + my ($xl, $yl, $xu, $yu) = ( 100000, 100000, -100000, -100000 ); + for ( @$aref ) { + $xl = ($_->[0] < $xl) ? $_->[0] : $xl; + $yl = ($_->[1] < $yl) ? $_->[1] : $yl; + $xu = ($_->[0] > $xu) ? $_->[0] : $xu; + $yu = ($_->[1] > $yu) ? $_->[1] : $yu; + } + return [($xl+$xu)/2, ($yl+$yu)/2, $xl, $yl, $xu, $yu]; +} + +#--- +sub rot_Array { + my ($mp, $ar) = @_; + my $a = $opt_a/360*2*PI; + my ($ca, $sa) = (cos($a), sin($a)); + return + [ + map { [ ($ca*($_->[0]-$mp->[0]) + (-$sa*($_->[1]-$mp->[1])))+$mp->[0], + ($sa*($_->[0]-$mp->[0]) + $ca*($_->[1]-$mp->[1])) +$mp->[1] + ] } @$ar ]; +} +#--- +sub flip_Array { + my ($mp, $ar) = @_; + return + [ map { [ ($mp->[0]-$_->[0]), $_->[1]] } @$ar ]; +} + +#--- +sub print_ss_ps { + local $_; + my $ar = shift; + for (qw/Header Coords BPairs Tailer/) { + if ($_ eq 'Coords') { + print "/coor [\n"; + for my $xy (@$ar) { + print sprintf("[%7.3f %7.3f]\n", $xy->[0], $xy->[1]); + } + print "] def\n"; + next; + } + print join "", @{$ss_ps->{$_}}; + } +} + +=head1 NAME + +rotate_ss - rotate or mirror coordinates of secondary structure plot + +=head1 SYNOPSIS + + rotate_ss.pl [-a angle] [-m] old_ss.ps > new_ss.ps + +=head1 DESCRIPTION + +B reads a PostScript RNA secondary structure plot, as +produced by B or B, rotates and/or mirrors the +coordinates, and writes the new plot to STDOUT. + +=head1 OPTIONS + +=over 4 + +=item B<-a> I + +Rotate the plot counter-clockwise by I degrees. + +=item B<-m> + +Mirror the coordinates in the plot, i.e. convert from a +couter-clockwise to clockwise layout. Note that, if both B<-m> and +B<-a> are given, the plot is first mirrored, then rotated. + +=back + +=head1 AUTHORS + +Ivo L. Hofacker , +Christoph Flamm + +=cut + +__END__ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec new file mode 100755 index 00000000..98c633d5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec @@ -0,0 +1,95 @@ +# barriers.spec +# +# Copyright (c) 2001 Ivo Hofacker, Peter Stadler, ivo@tbi.univie.ac.at +# +%define name ViennaRNA +%define version 1.6 +%define release 1 +%define manifest %{_builddir}/%{name}-%{version}-%{release}.manifest + +# required items +Name: %{name} +Version: %{version} +Release: %{release} +Copyright: GPL +Group: Application/Misc + +# optional items +Vendor: Ivo Hofacker, Peter Stadler, TBI +#Distribution: +#Icon: +URL: http://www.tbi.univie.ac.at/~ivo/RNA/ +Packager: Ivo Hofacker, ivo@tbi.univie.ac.at + +# source + patches +Source: %{name}-%{version}.tar.gz +#Source1: +#Patch: +#Patch1: + +# RPM info +Provides: libRNA.a +#Requires: +#Conflicts: +#Prereq: + +#Prefix: /usr +BuildRoot: /var/tmp/%{name}-%{version} + +Summary: RNA secondary structure prediction and analysis. + +%description +The ViennaRNA package consists of a library and several standalone +programs for RNA secondary structure analysis. It includes algorithms +for predicting optimal and suboptimal secondary structures, base pair +probabilities and partition functions, for comparing secondary +structures, and the design of RNA sequences with a desired structure. + + +%prep +%setup -q +#%patch0 -p1 + +%build +%configure +make + +%install +rm -rf $RPM_BUILD_ROOT +mkdir -p $RPM_BUILD_ROOT +%makeinstall + +# __os_install_post is implicitly expanded after the +# %install section... do it now, and then disable it, +# so all work is done before building manifest. + +%{?__os_install_post} +%define __os_install_post %{nil} + +# build the file list automagically into %{manifest} + +cd $RPM_BUILD_ROOT +rm -f %{manifest} +find . -type d \ + | sed '1,2d;s,^\.,\%attr(-\,root\,root) \%dir ,' >> %{manifest} +find . -type f \ + | sed 's,^\.,\%attr(-\,root\,root) ,' >> %{manifest} +find . -type l \ + | sed 's,^\.,\%attr(-\,root\,root) ,' >> %{manifest} + +#%pre +#%post +#%preun +#%postun + +%clean +rm -f %{manifest} +rm -rf $RPM_BUILD_ROOT + +%files -f %{manifest} +%defattr(-,root,root) +#%doc README +#%docdir +#%config + +%changelog diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec.in new file mode 100755 index 00000000..5a20604d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/ViennaRNA.spec.in @@ -0,0 +1,95 @@ +# barriers.spec +# +# Copyright (c) 2001 Ivo Hofacker, Peter Stadler, ivo@tbi.univie.ac.at +# +%define name ViennaRNA +%define version @VERSION@ +%define release 1 +%define manifest %{_builddir}/%{name}-%{version}-%{release}.manifest + +# required items +Name: %{name} +Version: %{version} +Release: %{release} +Copyright: GPL +Group: Application/Misc + +# optional items +Vendor: Ivo Hofacker, Peter Stadler, TBI +#Distribution: +#Icon: +URL: http://www.tbi.univie.ac.at/~ivo/RNA/ +Packager: Ivo Hofacker, ivo@tbi.univie.ac.at + +# source + patches +Source: %{name}-%{version}.tar.gz +#Source1: +#Patch: +#Patch1: + +# RPM info +Provides: libRNA.a +#Requires: +#Conflicts: +#Prereq: + +#Prefix: /usr +BuildRoot: /var/tmp/%{name}-%{version} + +Summary: RNA secondary structure prediction and analysis. + +%description +The ViennaRNA package consists of a library and several standalone +programs for RNA secondary structure analysis. It includes algorithms +for predicting optimal and suboptimal secondary structures, base pair +probabilities and partition functions, for comparing secondary +structures, and the design of RNA sequences with a desired structure. + + +%prep +%setup -q +#%patch0 -p1 + +%build +%configure +make + +%install +rm -rf $RPM_BUILD_ROOT +mkdir -p $RPM_BUILD_ROOT +%makeinstall + +# __os_install_post is implicitly expanded after the +# %install section... do it now, and then disable it, +# so all work is done before building manifest. + +%{?__os_install_post} +%define __os_install_post %{nil} + +# build the file list automagically into %{manifest} + +cd $RPM_BUILD_ROOT +rm -f %{manifest} +find . -type d \ + | sed '1,2d;s,^\.,\%attr(-\,root\,root) \%dir ,' >> %{manifest} +find . -type f \ + | sed 's,^\.,\%attr(-\,root\,root) ,' >> %{manifest} +find . -type l \ + | sed 's,^\.,\%attr(-\,root\,root) ,' >> %{manifest} + +#%pre +#%post +#%preun +#%postun + +%clean +rm -f %{manifest} +rm -rf $RPM_BUILD_ROOT + +%files -f %{manifest} +%defattr(-,root,root) +#%doc README +#%docdir +#%config + +%changelog diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/aclocal.m4 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/aclocal.m4 new file mode 100755 index 00000000..36033f6d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/aclocal.m4 @@ -0,0 +1,878 @@ +# generated automatically by aclocal 1.9.5 -*- Autoconf -*- + +# Copyright (C) 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, +# 2005 Free Software Foundation, Inc. +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY, to the extent permitted by law; without +# even the implied warranty of MERCHANTABILITY or FITNESS FOR A +# PARTICULAR PURPOSE. + +# Copyright (C) 2002, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# AM_AUTOMAKE_VERSION(VERSION) +# ---------------------------- +# Automake X.Y traces this macro to ensure aclocal.m4 has been +# generated from the m4 files accompanying Automake X.Y. +AC_DEFUN([AM_AUTOMAKE_VERSION], [am__api_version="1.9"]) + +# AM_SET_CURRENT_AUTOMAKE_VERSION +# ------------------------------- +# Call AM_AUTOMAKE_VERSION so it can be traced. +# This function is AC_REQUIREd by AC_INIT_AUTOMAKE. +AC_DEFUN([AM_SET_CURRENT_AUTOMAKE_VERSION], + [AM_AUTOMAKE_VERSION([1.9.5])]) + +# AM_AUX_DIR_EXPAND -*- Autoconf -*- + +# Copyright (C) 2001, 2003, 2005 Free Software Foundation, Inc. +# +# This file is free software; the Free Software Foundation +# gives unlimited permission to copy and/or distribute it, +# with or without modifications, as long as this notice is preserved. + +# For projects using AC_CONFIG_AUX_DIR([foo]), Autoconf sets +# $ac_aux_dir to `$srcdir/foo'. 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See the GNU +# General Public License for more details. +# +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA. +# +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Originally written by Per Bothner . +# Please send patches to . Submit a context +# diff and a properly formatted ChangeLog entry. +# +# This script attempts to guess a canonical system name similar to +# config.sub. If it succeeds, it prints the system name on stdout, and +# exits with 0. Otherwise, it exits with 1. +# +# The plan is that this can be called by configure scripts if you +# don't specify an explicit build system type. + +me=`echo "$0" | sed -e 's,.*/,,'` + +usage="\ +Usage: $0 [OPTION] + +Output the configuration name of the system \`$me' is run on. + +Operation modes: + -h, --help print this help, then exit + -t, --time-stamp print date of last modification, then exit + -v, --version print version number, then exit + +Report bugs and patches to ." + +version="\ +GNU config.guess ($timestamp) + +Originally written by Per Bothner. +Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004 +Free Software Foundation, Inc. + +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE." + +help=" +Try \`$me --help' for more information." + +# Parse command line +while test $# -gt 0 ; do + case $1 in + --time-stamp | --time* | -t ) + echo "$timestamp" ; exit 0 ;; + --version | -v ) + echo "$version" ; exit 0 ;; + --help | --h* | -h ) + echo "$usage"; exit 0 ;; + -- ) # Stop option processing + shift; break ;; + - ) # Use stdin as input. + break ;; + -* ) + echo "$me: invalid option $1$help" >&2 + exit 1 ;; + * ) + break ;; + esac +done + +if test $# != 0; then + echo "$me: too many arguments$help" >&2 + exit 1 +fi + +trap 'exit 1' 1 2 15 + +# CC_FOR_BUILD -- compiler used by this script. Note that the use of a +# compiler to aid in system detection is discouraged as it requires +# temporary files to be created and, as you can see below, it is a +# headache to deal with in a portable fashion. + +# Historically, `CC_FOR_BUILD' used to be named `HOST_CC'. We still +# use `HOST_CC' if defined, but it is deprecated. + +# Portable tmp directory creation inspired by the Autoconf team. + +set_cc_for_build=' +trap "exitcode=\$?; (rm -f \$tmpfiles 2>/dev/null; rmdir \$tmp 2>/dev/null) && exit \$exitcode" 0 ; +trap "rm -f \$tmpfiles 2>/dev/null; rmdir \$tmp 2>/dev/null; exit 1" 1 2 13 15 ; +: ${TMPDIR=/tmp} ; + { tmp=`(umask 077 && mktemp -d -q "$TMPDIR/cgXXXXXX") 2>/dev/null` && test -n "$tmp" && test -d "$tmp" ; } || + { test -n "$RANDOM" && tmp=$TMPDIR/cg$$-$RANDOM && (umask 077 && mkdir $tmp) ; } || + { tmp=$TMPDIR/cg-$$ && (umask 077 && mkdir $tmp) && echo "Warning: creating insecure temp directory" >&2 ; } || + { echo "$me: cannot create a temporary directory in $TMPDIR" >&2 ; exit 1 ; } ; +dummy=$tmp/dummy ; +tmpfiles="$dummy.c $dummy.o $dummy.rel $dummy" ; +case $CC_FOR_BUILD,$HOST_CC,$CC in + ,,) echo "int x;" > $dummy.c ; + for c in cc gcc c89 c99 ; do + if ($c -c -o $dummy.o $dummy.c) >/dev/null 2>&1 ; then + CC_FOR_BUILD="$c"; break ; + fi ; + done ; + if test x"$CC_FOR_BUILD" = x ; then + CC_FOR_BUILD=no_compiler_found ; + fi + ;; + ,,*) CC_FOR_BUILD=$CC ;; + ,*,*) CC_FOR_BUILD=$HOST_CC ;; +esac ;' + +# This is needed to find uname on a Pyramid OSx when run in the BSD universe. +# (ghazi@noc.rutgers.edu 1994-08-24) +if (test -f /.attbin/uname) >/dev/null 2>&1 ; then + PATH=$PATH:/.attbin ; export PATH +fi + +UNAME_MACHINE=`(uname -m) 2>/dev/null` || UNAME_MACHINE=unknown +UNAME_RELEASE=`(uname -r) 2>/dev/null` || UNAME_RELEASE=unknown +UNAME_SYSTEM=`(uname -s) 2>/dev/null` || UNAME_SYSTEM=unknown +UNAME_VERSION=`(uname -v) 2>/dev/null` || UNAME_VERSION=unknown + +# Note: order is significant - the case branches are not exclusive. + +case "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" in + *:NetBSD:*:*) + # NetBSD (nbsd) targets should (where applicable) match one or + # more of the tupples: *-*-netbsdelf*, *-*-netbsdaout*, + # *-*-netbsdecoff* and *-*-netbsd*. For targets that recently + # switched to ELF, *-*-netbsd* would select the old + # object file format. This provides both forward + # compatibility and a consistent mechanism for selecting the + # object file format. + # + # Note: NetBSD doesn't particularly care about the vendor + # portion of the name. We always set it to "unknown". + sysctl="sysctl -n hw.machine_arch" + UNAME_MACHINE_ARCH=`(/sbin/$sysctl 2>/dev/null || \ + /usr/sbin/$sysctl 2>/dev/null || echo unknown)` + case "${UNAME_MACHINE_ARCH}" in + armeb) machine=armeb-unknown ;; + arm*) machine=arm-unknown ;; + sh3el) machine=shl-unknown ;; + sh3eb) machine=sh-unknown ;; + *) machine=${UNAME_MACHINE_ARCH}-unknown ;; + esac + # The Operating System including object format, if it has switched + # to ELF recently, or will in the future. + case "${UNAME_MACHINE_ARCH}" in + arm*|i386|m68k|ns32k|sh3*|sparc|vax) + eval $set_cc_for_build + if echo __ELF__ | $CC_FOR_BUILD -E - 2>/dev/null \ + | grep __ELF__ >/dev/null + then + # Once all utilities can be ECOFF (netbsdecoff) or a.out (netbsdaout). + # Return netbsd for either. FIX? + os=netbsd + else + os=netbsdelf + fi + ;; + *) + os=netbsd + ;; + esac + # The OS release + # Debian GNU/NetBSD machines have a different userland, and + # thus, need a distinct triplet. However, they do not need + # kernel version information, so it can be replaced with a + # suitable tag, in the style of linux-gnu. + case "${UNAME_VERSION}" in + Debian*) + release='-gnu' + ;; + *) + release=`echo ${UNAME_RELEASE}|sed -e 's/[-_].*/\./'` + ;; + esac + # Since CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM: + # contains redundant information, the shorter form: + # CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM is used. + echo "${machine}-${os}${release}" + exit 0 ;; + amd64:OpenBSD:*:*) + echo x86_64-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + amiga:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + arc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + cats:OpenBSD:*:*) + echo arm-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + hp300:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + luna88k:OpenBSD:*:*) + echo m88k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mac68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + macppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme68k:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvme88k:OpenBSD:*:*) + echo m88k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + mvmeppc:OpenBSD:*:*) + echo powerpc-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + pmax:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sgi:OpenBSD:*:*) + echo mipseb-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + sun3:OpenBSD:*:*) + echo m68k-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + wgrisc:OpenBSD:*:*) + echo mipsel-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + *:OpenBSD:*:*) + echo ${UNAME_MACHINE}-unknown-openbsd${UNAME_RELEASE} + exit 0 ;; + *:ekkoBSD:*:*) + echo ${UNAME_MACHINE}-unknown-ekkobsd${UNAME_RELEASE} + exit 0 ;; + macppc:MirBSD:*:*) + echo powerppc-unknown-mirbsd${UNAME_RELEASE} + exit 0 ;; + *:MirBSD:*:*) + echo ${UNAME_MACHINE}-unknown-mirbsd${UNAME_RELEASE} + exit 0 ;; + alpha:OSF1:*:*) + case $UNAME_RELEASE in + *4.0) + UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $3}'` + ;; + *5.*) + UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $4}'` + ;; + esac + # According to Compaq, /usr/sbin/psrinfo has been available on + # OSF/1 and Tru64 systems produced since 1995. I hope that + # covers most systems running today. This code pipes the CPU + # types through head -n 1, so we only detect the type of CPU 0. + ALPHA_CPU_TYPE=`/usr/sbin/psrinfo -v | sed -n -e 's/^ The alpha \(.*\) processor.*$/\1/p' | head -n 1` + case "$ALPHA_CPU_TYPE" in + "EV4 (21064)") + UNAME_MACHINE="alpha" ;; + "EV4.5 (21064)") + UNAME_MACHINE="alpha" ;; + "LCA4 (21066/21068)") + UNAME_MACHINE="alpha" ;; + "EV5 (21164)") + UNAME_MACHINE="alphaev5" ;; + "EV5.6 (21164A)") + UNAME_MACHINE="alphaev56" ;; + "EV5.6 (21164PC)") + UNAME_MACHINE="alphapca56" ;; + "EV5.7 (21164PC)") + UNAME_MACHINE="alphapca57" ;; + "EV6 (21264)") + UNAME_MACHINE="alphaev6" ;; + "EV6.7 (21264A)") + UNAME_MACHINE="alphaev67" ;; + "EV6.8CB (21264C)") + UNAME_MACHINE="alphaev68" ;; + "EV6.8AL (21264B)") + UNAME_MACHINE="alphaev68" ;; + "EV6.8CX (21264D)") + UNAME_MACHINE="alphaev68" ;; + "EV6.9A (21264/EV69A)") + UNAME_MACHINE="alphaev69" ;; + "EV7 (21364)") + UNAME_MACHINE="alphaev7" ;; + "EV7.9 (21364A)") + UNAME_MACHINE="alphaev79" ;; + esac + # A Pn.n version is a patched version. + # A Vn.n version is a released version. + # A Tn.n version is a released field test version. + # A Xn.n version is an unreleased experimental baselevel. + # 1.2 uses "1.2" for uname -r. + echo ${UNAME_MACHINE}-dec-osf`echo ${UNAME_RELEASE} | sed -e 's/^[PVTX]//' | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + exit 0 ;; + Alpha\ *:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # Should we change UNAME_MACHINE based on the output of uname instead + # of the specific Alpha model? + echo alpha-pc-interix + exit 0 ;; + 21064:Windows_NT:50:3) + echo alpha-dec-winnt3.5 + exit 0 ;; + Amiga*:UNIX_System_V:4.0:*) + echo m68k-unknown-sysv4 + exit 0;; + *:[Aa]miga[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-amigaos + exit 0 ;; + *:[Mm]orph[Oo][Ss]:*:*) + echo ${UNAME_MACHINE}-unknown-morphos + exit 0 ;; + *:OS/390:*:*) + echo i370-ibm-openedition + exit 0 ;; + *:OS400:*:*) + echo powerpc-ibm-os400 + exit 0 ;; + arm:RISC*:1.[012]*:*|arm:riscix:1.[012]*:*) + echo arm-acorn-riscix${UNAME_RELEASE} + exit 0;; + SR2?01:HI-UX/MPP:*:* | SR8000:HI-UX/MPP:*:*) + echo hppa1.1-hitachi-hiuxmpp + exit 0;; + Pyramid*:OSx*:*:* | MIS*:OSx*:*:* | MIS*:SMP_DC-OSx*:*:*) + # akee@wpdis03.wpafb.af.mil (Earle F. Ake) contributed MIS and NILE. + if test "`(/bin/universe) 2>/dev/null`" = att ; then + echo pyramid-pyramid-sysv3 + else + echo pyramid-pyramid-bsd + fi + exit 0 ;; + NILE*:*:*:dcosx) + echo pyramid-pyramid-svr4 + exit 0 ;; + DRS?6000:unix:4.0:6*) + echo sparc-icl-nx6 + exit 0 ;; + DRS?6000:UNIX_SV:4.2*:7*) + case `/usr/bin/uname -p` in + sparc) echo sparc-icl-nx7 && exit 0 ;; + esac ;; + sun4H:SunOS:5.*:*) + echo sparc-hal-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:5.*:* | tadpole*:SunOS:5.*:*) + echo sparc-sun-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + i86pc:SunOS:5.*:*) + echo i386-pc-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:6*:*) + # According to config.sub, this is the proper way to canonicalize + # SunOS6. Hard to guess exactly what SunOS6 will be like, but + # it's likely to be more like Solaris than SunOS4. + echo sparc-sun-solaris3`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + sun4*:SunOS:*:*) + case "`/usr/bin/arch -k`" in + Series*|S4*) + UNAME_RELEASE=`uname -v` + ;; + esac + # Japanese Language versions have a version number like `4.1.3-JL'. + echo sparc-sun-sunos`echo ${UNAME_RELEASE}|sed -e 's/-/_/'` + exit 0 ;; + sun3*:SunOS:*:*) + echo m68k-sun-sunos${UNAME_RELEASE} + exit 0 ;; + sun*:*:4.2BSD:*) + UNAME_RELEASE=`(sed 1q /etc/motd | awk '{print substr($5,1,3)}') 2>/dev/null` + test "x${UNAME_RELEASE}" = "x" && UNAME_RELEASE=3 + case "`/bin/arch`" in + sun3) + echo m68k-sun-sunos${UNAME_RELEASE} + ;; + sun4) + echo sparc-sun-sunos${UNAME_RELEASE} + ;; + esac + exit 0 ;; + aushp:SunOS:*:*) + echo sparc-auspex-sunos${UNAME_RELEASE} + exit 0 ;; + # The situation for MiNT is a little confusing. The machine name + # can be virtually everything (everything which is not + # "atarist" or "atariste" at least should have a processor + # > m68000). The system name ranges from "MiNT" over "FreeMiNT" + # to the lowercase version "mint" (or "freemint"). Finally + # the system name "TOS" denotes a system which is actually not + # MiNT. But MiNT is downward compatible to TOS, so this should + # be no problem. + atarist[e]:*MiNT:*:* | atarist[e]:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + atari*:*MiNT:*:* | atari*:*mint:*:* | atarist[e]:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + *falcon*:*MiNT:*:* | *falcon*:*mint:*:* | *falcon*:*TOS:*:*) + echo m68k-atari-mint${UNAME_RELEASE} + exit 0 ;; + milan*:*MiNT:*:* | milan*:*mint:*:* | *milan*:*TOS:*:*) + echo m68k-milan-mint${UNAME_RELEASE} + exit 0 ;; + hades*:*MiNT:*:* | hades*:*mint:*:* | *hades*:*TOS:*:*) + echo m68k-hades-mint${UNAME_RELEASE} + exit 0 ;; + *:*MiNT:*:* | *:*mint:*:* | *:*TOS:*:*) + echo m68k-unknown-mint${UNAME_RELEASE} + exit 0 ;; + m68k:machten:*:*) + echo m68k-apple-machten${UNAME_RELEASE} + exit 0 ;; + powerpc:machten:*:*) + echo powerpc-apple-machten${UNAME_RELEASE} + exit 0 ;; + RISC*:Mach:*:*) + echo mips-dec-mach_bsd4.3 + exit 0 ;; + RISC*:ULTRIX:*:*) + echo mips-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + VAX*:ULTRIX*:*:*) + echo vax-dec-ultrix${UNAME_RELEASE} + exit 0 ;; + 2020:CLIX:*:* | 2430:CLIX:*:*) + echo clipper-intergraph-clix${UNAME_RELEASE} + exit 0 ;; + mips:*:*:UMIPS | mips:*:*:RISCos) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c +#ifdef __cplusplus +#include /* for printf() prototype */ + int main (int argc, char *argv[]) { +#else + int main (argc, argv) int argc; char *argv[]; { +#endif + #if defined (host_mips) && defined (MIPSEB) + #if defined (SYSTYPE_SYSV) + printf ("mips-mips-riscos%ssysv\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_SVR4) + printf ("mips-mips-riscos%ssvr4\n", argv[1]); exit (0); + #endif + #if defined (SYSTYPE_BSD43) || defined(SYSTYPE_BSD) + printf ("mips-mips-riscos%sbsd\n", argv[1]); exit (0); + #endif + #endif + exit (-1); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c \ + && $dummy `echo "${UNAME_RELEASE}" | sed -n 's/\([0-9]*\).*/\1/p'` \ + && exit 0 + echo mips-mips-riscos${UNAME_RELEASE} + exit 0 ;; + Motorola:PowerMAX_OS:*:*) + echo powerpc-motorola-powermax + exit 0 ;; + Motorola:*:4.3:PL8-*) + echo powerpc-harris-powermax + exit 0 ;; + Night_Hawk:*:*:PowerMAX_OS | Synergy:PowerMAX_OS:*:*) + echo powerpc-harris-powermax + exit 0 ;; + Night_Hawk:Power_UNIX:*:*) + echo powerpc-harris-powerunix + exit 0 ;; + m88k:CX/UX:7*:*) + echo m88k-harris-cxux7 + exit 0 ;; + m88k:*:4*:R4*) + echo m88k-motorola-sysv4 + exit 0 ;; + m88k:*:3*:R3*) + echo m88k-motorola-sysv3 + exit 0 ;; + AViiON:dgux:*:*) + # DG/UX returns AViiON for all architectures + UNAME_PROCESSOR=`/usr/bin/uname -p` + if [ $UNAME_PROCESSOR = mc88100 ] || [ $UNAME_PROCESSOR = mc88110 ] + then + if [ ${TARGET_BINARY_INTERFACE}x = m88kdguxelfx ] || \ + [ ${TARGET_BINARY_INTERFACE}x = x ] + then + echo m88k-dg-dgux${UNAME_RELEASE} + else + echo m88k-dg-dguxbcs${UNAME_RELEASE} + fi + else + echo i586-dg-dgux${UNAME_RELEASE} + fi + exit 0 ;; + M88*:DolphinOS:*:*) # DolphinOS (SVR3) + echo m88k-dolphin-sysv3 + exit 0 ;; + M88*:*:R3*:*) + # Delta 88k system running SVR3 + echo m88k-motorola-sysv3 + exit 0 ;; + XD88*:*:*:*) # Tektronix XD88 system running UTekV (SVR3) + echo m88k-tektronix-sysv3 + exit 0 ;; + Tek43[0-9][0-9]:UTek:*:*) # Tektronix 4300 system running UTek (BSD) + echo m68k-tektronix-bsd + exit 0 ;; + *:IRIX*:*:*) + echo mips-sgi-irix`echo ${UNAME_RELEASE}|sed -e 's/-/_/g'` + exit 0 ;; + ????????:AIX?:[12].1:2) # AIX 2.2.1 or AIX 2.1.1 is RT/PC AIX. + echo romp-ibm-aix # uname -m gives an 8 hex-code CPU id + exit 0 ;; # Note that: echo "'`uname -s`'" gives 'AIX ' + i*86:AIX:*:*) + echo i386-ibm-aix + exit 0 ;; + ia64:AIX:*:*) + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${UNAME_MACHINE}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:2:3) + if grep bos325 /usr/include/stdio.h >/dev/null 2>&1; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + + main() + { + if (!__power_pc()) + exit(1); + puts("powerpc-ibm-aix3.2.5"); + exit(0); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c && $dummy && exit 0 + echo rs6000-ibm-aix3.2.5 + elif grep bos324 /usr/include/stdio.h >/dev/null 2>&1; then + echo rs6000-ibm-aix3.2.4 + else + echo rs6000-ibm-aix3.2 + fi + exit 0 ;; + *:AIX:*:[45]) + IBM_CPU_ID=`/usr/sbin/lsdev -C -c processor -S available | sed 1q | awk '{ print $1 }'` + if /usr/sbin/lsattr -El ${IBM_CPU_ID} | grep ' POWER' >/dev/null 2>&1; then + IBM_ARCH=rs6000 + else + IBM_ARCH=powerpc + fi + if [ -x /usr/bin/oslevel ] ; then + IBM_REV=`/usr/bin/oslevel` + else + IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE} + fi + echo ${IBM_ARCH}-ibm-aix${IBM_REV} + exit 0 ;; + *:AIX:*:*) + echo rs6000-ibm-aix + exit 0 ;; + ibmrt:4.4BSD:*|romp-ibm:BSD:*) + echo romp-ibm-bsd4.4 + exit 0 ;; + ibmrt:*BSD:*|romp-ibm:BSD:*) # covers RT/PC BSD and + echo romp-ibm-bsd${UNAME_RELEASE} # 4.3 with uname added to + exit 0 ;; # report: romp-ibm BSD 4.3 + *:BOSX:*:*) + echo rs6000-bull-bosx + exit 0 ;; + DPX/2?00:B.O.S.:*:*) + echo m68k-bull-sysv3 + exit 0 ;; + 9000/[34]??:4.3bsd:1.*:*) + echo m68k-hp-bsd + exit 0 ;; + hp300:4.4BSD:*:* | 9000/[34]??:4.3bsd:2.*:*) + echo m68k-hp-bsd4.4 + exit 0 ;; + 9000/[34678]??:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + case "${UNAME_MACHINE}" in + 9000/31? ) HP_ARCH=m68000 ;; + 9000/[34]?? ) HP_ARCH=m68k ;; + 9000/[678][0-9][0-9]) + if [ -x /usr/bin/getconf ]; then + sc_cpu_version=`/usr/bin/getconf SC_CPU_VERSION 2>/dev/null` + sc_kernel_bits=`/usr/bin/getconf SC_KERNEL_BITS 2>/dev/null` + case "${sc_cpu_version}" in + 523) HP_ARCH="hppa1.0" ;; # CPU_PA_RISC1_0 + 528) HP_ARCH="hppa1.1" ;; # CPU_PA_RISC1_1 + 532) # CPU_PA_RISC2_0 + case "${sc_kernel_bits}" in + 32) HP_ARCH="hppa2.0n" ;; + 64) HP_ARCH="hppa2.0w" ;; + '') HP_ARCH="hppa2.0" ;; # HP-UX 10.20 + esac ;; + esac + fi + if [ "${HP_ARCH}" = "" ]; then + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + + #define _HPUX_SOURCE + #include + #include + + int main () + { + #if defined(_SC_KERNEL_BITS) + long bits = sysconf(_SC_KERNEL_BITS); + #endif + long cpu = sysconf (_SC_CPU_VERSION); + + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1"); break; + case CPU_PA_RISC2_0: + #if defined(_SC_KERNEL_BITS) + switch (bits) + { + case 64: puts ("hppa2.0w"); break; + case 32: puts ("hppa2.0n"); break; + default: puts ("hppa2.0"); break; + } break; + #else /* !defined(_SC_KERNEL_BITS) */ + puts ("hppa2.0"); break; + #endif + default: puts ("hppa1.0"); break; + } + exit (0); + } +EOF + (CCOPTS= $CC_FOR_BUILD -o $dummy $dummy.c 2>/dev/null) && HP_ARCH=`$dummy` + test -z "$HP_ARCH" && HP_ARCH=hppa + fi ;; + esac + if [ ${HP_ARCH} = "hppa2.0w" ] + then + # avoid double evaluation of $set_cc_for_build + test -n "$CC_FOR_BUILD" || eval $set_cc_for_build + if echo __LP64__ | (CCOPTS= $CC_FOR_BUILD -E -) | grep __LP64__ >/dev/null + then + HP_ARCH="hppa2.0w" + else + HP_ARCH="hppa64" + fi + fi + echo ${HP_ARCH}-hp-hpux${HPUX_REV} + exit 0 ;; + ia64:HP-UX:*:*) + HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'` + echo ia64-hp-hpux${HPUX_REV} + exit 0 ;; + 3050*:HI-UX:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + int + main () + { + long cpu = sysconf (_SC_CPU_VERSION); + /* The order matters, because CPU_IS_HP_MC68K erroneously returns + true for CPU_PA_RISC1_0. CPU_IS_PA_RISC returns correct + results, however. */ + if (CPU_IS_PA_RISC (cpu)) + { + switch (cpu) + { + case CPU_PA_RISC1_0: puts ("hppa1.0-hitachi-hiuxwe2"); break; + case CPU_PA_RISC1_1: puts ("hppa1.1-hitachi-hiuxwe2"); break; + case CPU_PA_RISC2_0: puts ("hppa2.0-hitachi-hiuxwe2"); break; + default: puts ("hppa-hitachi-hiuxwe2"); break; + } + } + else if (CPU_IS_HP_MC68K (cpu)) + puts ("m68k-hitachi-hiuxwe2"); + else puts ("unknown-hitachi-hiuxwe2"); + exit (0); + } +EOF + $CC_FOR_BUILD -o $dummy $dummy.c && $dummy && exit 0 + echo unknown-hitachi-hiuxwe2 + exit 0 ;; + 9000/7??:4.3bsd:*:* | 9000/8?[79]:4.3bsd:*:* ) + echo hppa1.1-hp-bsd + exit 0 ;; + 9000/8??:4.3bsd:*:*) + echo hppa1.0-hp-bsd + exit 0 ;; + *9??*:MPE/iX:*:* | *3000*:MPE/iX:*:*) + echo hppa1.0-hp-mpeix + exit 0 ;; + hp7??:OSF1:*:* | hp8?[79]:OSF1:*:* ) + echo hppa1.1-hp-osf + exit 0 ;; + hp8??:OSF1:*:*) + echo hppa1.0-hp-osf + exit 0 ;; + i*86:OSF1:*:*) + if [ -x /usr/sbin/sysversion ] ; then + echo ${UNAME_MACHINE}-unknown-osf1mk + else + echo ${UNAME_MACHINE}-unknown-osf1 + fi + exit 0 ;; + parisc*:Lites*:*:*) + echo hppa1.1-hp-lites + exit 0 ;; + C1*:ConvexOS:*:* | convex:ConvexOS:C1*:*) + echo c1-convex-bsd + exit 0 ;; + C2*:ConvexOS:*:* | convex:ConvexOS:C2*:*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + C34*:ConvexOS:*:* | convex:ConvexOS:C34*:*) + echo c34-convex-bsd + exit 0 ;; + C38*:ConvexOS:*:* | convex:ConvexOS:C38*:*) + echo c38-convex-bsd + exit 0 ;; + C4*:ConvexOS:*:* | convex:ConvexOS:C4*:*) + echo c4-convex-bsd + exit 0 ;; + CRAY*Y-MP:*:*:*) + echo ymp-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*[A-Z]90:*:*:*) + echo ${UNAME_MACHINE}-cray-unicos${UNAME_RELEASE} \ + | sed -e 's/CRAY.*\([A-Z]90\)/\1/' \ + -e y/ABCDEFGHIJKLMNOPQRSTUVWXYZ/abcdefghijklmnopqrstuvwxyz/ \ + -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*TS:*:*:*) + echo t90-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*T3E:*:*:*) + echo alphaev5-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + CRAY*SV1:*:*:*) + echo sv1-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + *:UNICOS/mp:*:*) + echo craynv-cray-unicosmp${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/' + exit 0 ;; + F30[01]:UNIX_System_V:*:* | F700:UNIX_System_V:*:*) + FUJITSU_PROC=`uname -m | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'` + FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'` + FUJITSU_REL=`echo ${UNAME_RELEASE} | sed -e 's/ /_/'` + echo "${FUJITSU_PROC}-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}" + exit 0 ;; + 5000:UNIX_System_V:4.*:*) + FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'` + FUJITSU_REL=`echo ${UNAME_RELEASE} | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/ /_/'` + echo "sparc-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}" + exit 0 ;; + i*86:BSD/386:*:* | i*86:BSD/OS:*:* | *:Ascend\ Embedded/OS:*:*) + echo ${UNAME_MACHINE}-pc-bsdi${UNAME_RELEASE} + exit 0 ;; + sparc*:BSD/OS:*:*) + echo sparc-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:BSD/OS:*:*) + echo ${UNAME_MACHINE}-unknown-bsdi${UNAME_RELEASE} + exit 0 ;; + *:FreeBSD:*:*) + echo ${UNAME_MACHINE}-unknown-freebsd`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'` + exit 0 ;; + i*:CYGWIN*:*) + echo ${UNAME_MACHINE}-pc-cygwin + exit 0 ;; + i*:MINGW*:*) + echo ${UNAME_MACHINE}-pc-mingw32 + exit 0 ;; + i*:PW*:*) + echo ${UNAME_MACHINE}-pc-pw32 + exit 0 ;; + x86:Interix*:[34]*) + echo i586-pc-interix${UNAME_RELEASE}|sed -e 's/\..*//' + exit 0 ;; + [345]86:Windows_95:* | [345]86:Windows_98:* | [345]86:Windows_NT:*) + echo i${UNAME_MACHINE}-pc-mks + exit 0 ;; + i*:Windows_NT*:* | Pentium*:Windows_NT*:*) + # How do we know it's Interix rather than the generic POSIX subsystem? + # It also conflicts with pre-2.0 versions of AT&T UWIN. Should we + # UNAME_MACHINE based on the output of uname instead of i386? + echo i586-pc-interix + exit 0 ;; + i*:UWIN*:*) + echo ${UNAME_MACHINE}-pc-uwin + exit 0 ;; + p*:CYGWIN*:*) + echo powerpcle-unknown-cygwin + exit 0 ;; + prep*:SunOS:5.*:*) + echo powerpcle-unknown-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'` + exit 0 ;; + *:GNU:*:*) + # the GNU system + echo `echo ${UNAME_MACHINE}|sed -e 's,[-/].*$,,'`-unknown-gnu`echo ${UNAME_RELEASE}|sed -e 's,/.*$,,'` + exit 0 ;; + *:GNU/*:*:*) + # other systems with GNU libc and userland + echo ${UNAME_MACHINE}-unknown-`echo ${UNAME_SYSTEM} | sed 's,^[^/]*/,,' | tr '[A-Z]' '[a-z]'``echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'`-gnu + exit 0 ;; + i*86:Minix:*:*) + echo ${UNAME_MACHINE}-pc-minix + exit 0 ;; + arm*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + cris:Linux:*:*) + echo cris-axis-linux-gnu + exit 0 ;; + ia64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + m32r*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + m68*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + mips:Linux:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #undef CPU + #undef mips + #undef mipsel + #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) + CPU=mipsel + #else + #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) + CPU=mips + #else + CPU= + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=` + test x"${CPU}" != x && echo "${CPU}-unknown-linux-gnu" && exit 0 + ;; + mips64:Linux:*:*) + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #undef CPU + #undef mips64 + #undef mips64el + #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL) + CPU=mips64el + #else + #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB) + CPU=mips64 + #else + CPU= + #endif + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=` + test x"${CPU}" != x && echo "${CPU}-unknown-linux-gnu" && exit 0 + ;; + ppc:Linux:*:*) + echo powerpc-unknown-linux-gnu + exit 0 ;; + ppc64:Linux:*:*) + echo powerpc64-unknown-linux-gnu + exit 0 ;; + alpha:Linux:*:*) + case `sed -n '/^cpu model/s/^.*: \(.*\)/\1/p' < /proc/cpuinfo` in + EV5) UNAME_MACHINE=alphaev5 ;; + EV56) UNAME_MACHINE=alphaev56 ;; + PCA56) UNAME_MACHINE=alphapca56 ;; + PCA57) UNAME_MACHINE=alphapca56 ;; + EV6) UNAME_MACHINE=alphaev6 ;; + EV67) UNAME_MACHINE=alphaev67 ;; + EV68*) UNAME_MACHINE=alphaev68 ;; + esac + objdump --private-headers /bin/sh | grep ld.so.1 >/dev/null + if test "$?" = 0 ; then LIBC="libc1" ; else LIBC="" ; fi + echo ${UNAME_MACHINE}-unknown-linux-gnu${LIBC} + exit 0 ;; + parisc:Linux:*:* | hppa:Linux:*:*) + # Look for CPU level + case `grep '^cpu[^a-z]*:' /proc/cpuinfo 2>/dev/null | cut -d' ' -f2` in + PA7*) echo hppa1.1-unknown-linux-gnu ;; + PA8*) echo hppa2.0-unknown-linux-gnu ;; + *) echo hppa-unknown-linux-gnu ;; + esac + exit 0 ;; + parisc64:Linux:*:* | hppa64:Linux:*:*) + echo hppa64-unknown-linux-gnu + exit 0 ;; + s390:Linux:*:* | s390x:Linux:*:*) + echo ${UNAME_MACHINE}-ibm-linux + exit 0 ;; + sh64*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + sh*:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + sparc:Linux:*:* | sparc64:Linux:*:*) + echo ${UNAME_MACHINE}-unknown-linux-gnu + exit 0 ;; + x86_64:Linux:*:*) + echo x86_64-unknown-linux-gnu + exit 0 ;; + i*86:Linux:*:*) + # The BFD linker knows what the default object file format is, so + # first see if it will tell us. cd to the root directory to prevent + # problems with other programs or directories called `ld' in the path. + # Set LC_ALL=C to ensure ld outputs messages in English. + ld_supported_targets=`cd /; LC_ALL=C ld --help 2>&1 \ + | sed -ne '/supported targets:/!d + s/[ ][ ]*/ /g + s/.*supported targets: *// + s/ .*// + p'` + case "$ld_supported_targets" in + elf32-i386) + TENTATIVE="${UNAME_MACHINE}-pc-linux-gnu" + ;; + a.out-i386-linux) + echo "${UNAME_MACHINE}-pc-linux-gnuaout" + exit 0 ;; + coff-i386) + echo "${UNAME_MACHINE}-pc-linux-gnucoff" + exit 0 ;; + "") + # Either a pre-BFD a.out linker (linux-gnuoldld) or + # one that does not give us useful --help. + echo "${UNAME_MACHINE}-pc-linux-gnuoldld" + exit 0 ;; + esac + # Determine whether the default compiler is a.out or elf + eval $set_cc_for_build + sed 's/^ //' << EOF >$dummy.c + #include + #ifdef __ELF__ + # ifdef __GLIBC__ + # if __GLIBC__ >= 2 + LIBC=gnu + # else + LIBC=gnulibc1 + # endif + # else + LIBC=gnulibc1 + # endif + #else + #ifdef __INTEL_COMPILER + LIBC=gnu + #else + LIBC=gnuaout + #endif + #endif + #ifdef __dietlibc__ + LIBC=dietlibc + #endif +EOF + eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=` + test x"${LIBC}" != x && echo "${UNAME_MACHINE}-pc-linux-${LIBC}" && exit 0 + test x"${TENTATIVE}" != x && echo "${TENTATIVE}" && exit 0 + ;; + i*86:DYNIX/ptx:4*:*) + # ptx 4.0 does uname -s correctly, with DYNIX/ptx in there. + # earlier versions are messed up and put the nodename in both + # sysname and nodename. + echo i386-sequent-sysv4 + exit 0 ;; + i*86:UNIX_SV:4.2MP:2.*) + # Unixware is an offshoot of SVR4, but it has its own version + # number series starting with 2... + # I am not positive that other SVR4 systems won't match this, + # I just have to hope. -- rms. + # Use sysv4.2uw... so that sysv4* matches it. + echo ${UNAME_MACHINE}-pc-sysv4.2uw${UNAME_VERSION} + exit 0 ;; + i*86:OS/2:*:*) + # If we were able to find `uname', then EMX Unix compatibility + # is probably installed. + echo ${UNAME_MACHINE}-pc-os2-emx + exit 0 ;; + i*86:XTS-300:*:STOP) + echo ${UNAME_MACHINE}-unknown-stop + exit 0 ;; + i*86:atheos:*:*) + echo ${UNAME_MACHINE}-unknown-atheos + exit 0 ;; + i*86:syllable:*:*) + echo ${UNAME_MACHINE}-pc-syllable + exit 0 ;; + i*86:LynxOS:2.*:* | i*86:LynxOS:3.[01]*:* | i*86:LynxOS:4.0*:*) + echo i386-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + i*86:*DOS:*:*) + echo ${UNAME_MACHINE}-pc-msdosdjgpp + exit 0 ;; + i*86:*:4.*:* | i*86:SYSTEM_V:4.*:*) + UNAME_REL=`echo ${UNAME_RELEASE} | sed 's/\/MP$//'` + if grep Novell /usr/include/link.h >/dev/null 2>/dev/null; then + echo ${UNAME_MACHINE}-univel-sysv${UNAME_REL} + else + echo ${UNAME_MACHINE}-pc-sysv${UNAME_REL} + fi + exit 0 ;; + i*86:*:5:[78]*) + case `/bin/uname -X | grep "^Machine"` in + *486*) UNAME_MACHINE=i486 ;; + *Pentium) UNAME_MACHINE=i586 ;; + *Pent*|*Celeron) UNAME_MACHINE=i686 ;; + esac + echo ${UNAME_MACHINE}-unknown-sysv${UNAME_RELEASE}${UNAME_SYSTEM}${UNAME_VERSION} + exit 0 ;; + i*86:*:3.2:*) + if test -f /usr/options/cb.name; then + UNAME_REL=`sed -n 's/.*Version //p' /dev/null >/dev/null ; then + UNAME_REL=`(/bin/uname -X|grep Release|sed -e 's/.*= //')` + (/bin/uname -X|grep i80486 >/dev/null) && UNAME_MACHINE=i486 + (/bin/uname -X|grep '^Machine.*Pentium' >/dev/null) \ + && UNAME_MACHINE=i586 + (/bin/uname -X|grep '^Machine.*Pent *II' >/dev/null) \ + && UNAME_MACHINE=i686 + (/bin/uname -X|grep '^Machine.*Pentium Pro' >/dev/null) \ + && UNAME_MACHINE=i686 + echo ${UNAME_MACHINE}-pc-sco$UNAME_REL + else + echo ${UNAME_MACHINE}-pc-sysv32 + fi + exit 0 ;; + pc:*:*:*) + # Left here for compatibility: + # uname -m prints for DJGPP always 'pc', but it prints nothing about + # the processor, so we play safe by assuming i386. + echo i386-pc-msdosdjgpp + exit 0 ;; + Intel:Mach:3*:*) + echo i386-pc-mach3 + exit 0 ;; + paragon:*:*:*) + echo i860-intel-osf1 + exit 0 ;; + i860:*:4.*:*) # i860-SVR4 + if grep Stardent /usr/include/sys/uadmin.h >/dev/null 2>&1 ; then + echo i860-stardent-sysv${UNAME_RELEASE} # Stardent Vistra i860-SVR4 + else # Add other i860-SVR4 vendors below as they are discovered. + echo i860-unknown-sysv${UNAME_RELEASE} # Unknown i860-SVR4 + fi + exit 0 ;; + mini*:CTIX:SYS*5:*) + # "miniframe" + echo m68010-convergent-sysv + exit 0 ;; + mc68k:UNIX:SYSTEM5:3.51m) + echo m68k-convergent-sysv + exit 0 ;; + M680?0:D-NIX:5.3:*) + echo m68k-diab-dnix + exit 0 ;; + M68*:*:R3V[5678]*:*) + test -r /sysV68 && echo 'm68k-motorola-sysv' && exit 0 ;; + 3[345]??:*:4.0:3.0 | 3[34]??A:*:4.0:3.0 | 3[34]??,*:*:4.0:3.0 | 3[34]??/*:*:4.0:3.0 | 4400:*:4.0:3.0 | 4850:*:4.0:3.0 | SKA40:*:4.0:3.0 | SDS2:*:4.0:3.0 | SHG2:*:4.0:3.0 | S7501*:*:4.0:3.0) + OS_REL='' + test -r /etc/.relid \ + && OS_REL=.`sed -n 's/[^ ]* [^ ]* \([0-9][0-9]\).*/\1/p' < /etc/.relid` + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4.3${OS_REL} && exit 0 + /bin/uname -p 2>/dev/null | /bin/grep entium >/dev/null \ + && echo i586-ncr-sysv4.3${OS_REL} && exit 0 ;; + 3[34]??:*:4.0:* | 3[34]??,*:*:4.0:*) + /bin/uname -p 2>/dev/null | grep 86 >/dev/null \ + && echo i486-ncr-sysv4 && exit 0 ;; + m68*:LynxOS:2.*:* | m68*:LynxOS:3.0*:*) + echo m68k-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + mc68030:UNIX_System_V:4.*:*) + echo m68k-atari-sysv4 + exit 0 ;; + TSUNAMI:LynxOS:2.*:*) + echo sparc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + rs6000:LynxOS:2.*:*) + echo rs6000-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + PowerPC:LynxOS:2.*:* | PowerPC:LynxOS:3.[01]*:* | PowerPC:LynxOS:4.0*:*) + echo powerpc-unknown-lynxos${UNAME_RELEASE} + exit 0 ;; + SM[BE]S:UNIX_SV:*:*) + echo mips-dde-sysv${UNAME_RELEASE} + exit 0 ;; + RM*:ReliantUNIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + RM*:SINIX-*:*:*) + echo mips-sni-sysv4 + exit 0 ;; + *:SINIX-*:*:*) + if uname -p 2>/dev/null >/dev/null ; then + UNAME_MACHINE=`(uname -p) 2>/dev/null` + echo ${UNAME_MACHINE}-sni-sysv4 + else + echo ns32k-sni-sysv + fi + exit 0 ;; + PENTIUM:*:4.0*:*) # Unisys `ClearPath HMP IX 4000' SVR4/MP effort + # says + echo i586-unisys-sysv4 + exit 0 ;; + *:UNIX_System_V:4*:FTX*) + # From Gerald Hewes . + # How about differentiating between stratus architectures? -djm + echo hppa1.1-stratus-sysv4 + exit 0 ;; + *:*:*:FTX*) + # From seanf@swdc.stratus.com. + echo i860-stratus-sysv4 + exit 0 ;; + *:VOS:*:*) + # From Paul.Green@stratus.com. + echo hppa1.1-stratus-vos + exit 0 ;; + mc68*:A/UX:*:*) + echo m68k-apple-aux${UNAME_RELEASE} + exit 0 ;; + news*:NEWS-OS:6*:*) + echo mips-sony-newsos6 + exit 0 ;; + R[34]000:*System_V*:*:* | R4000:UNIX_SYSV:*:* | R*000:UNIX_SV:*:*) + if [ -d /usr/nec ]; then + echo mips-nec-sysv${UNAME_RELEASE} + else + echo mips-unknown-sysv${UNAME_RELEASE} + fi + exit 0 ;; + BeBox:BeOS:*:*) # BeOS running on hardware made by Be, PPC only. + echo powerpc-be-beos + exit 0 ;; + BeMac:BeOS:*:*) # BeOS running on Mac or Mac clone, PPC only. + echo powerpc-apple-beos + exit 0 ;; + BePC:BeOS:*:*) # BeOS running on Intel PC compatible. + echo i586-pc-beos + exit 0 ;; + SX-4:SUPER-UX:*:*) + echo sx4-nec-superux${UNAME_RELEASE} + exit 0 ;; + SX-5:SUPER-UX:*:*) + echo sx5-nec-superux${UNAME_RELEASE} + exit 0 ;; + SX-6:SUPER-UX:*:*) + echo sx6-nec-superux${UNAME_RELEASE} + exit 0 ;; + Power*:Rhapsody:*:*) + echo powerpc-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Rhapsody:*:*) + echo ${UNAME_MACHINE}-apple-rhapsody${UNAME_RELEASE} + exit 0 ;; + *:Darwin:*:*) + UNAME_PROCESSOR=`uname -p` || UNAME_PROCESSOR=unknown + case $UNAME_PROCESSOR in + *86) UNAME_PROCESSOR=i686 ;; + unknown) UNAME_PROCESSOR=powerpc ;; + esac + echo ${UNAME_PROCESSOR}-apple-darwin${UNAME_RELEASE} + exit 0 ;; + *:procnto*:*:* | *:QNX:[0123456789]*:*) + UNAME_PROCESSOR=`uname -p` + if test "$UNAME_PROCESSOR" = "x86"; then + UNAME_PROCESSOR=i386 + UNAME_MACHINE=pc + fi + echo ${UNAME_PROCESSOR}-${UNAME_MACHINE}-nto-qnx${UNAME_RELEASE} + exit 0 ;; + *:QNX:*:4*) + echo i386-pc-qnx + exit 0 ;; + NSR-?:NONSTOP_KERNEL:*:*) + echo nsr-tandem-nsk${UNAME_RELEASE} + exit 0 ;; + *:NonStop-UX:*:*) + echo mips-compaq-nonstopux + exit 0 ;; + BS2000:POSIX*:*:*) + echo bs2000-siemens-sysv + exit 0 ;; + DS/*:UNIX_System_V:*:*) + echo ${UNAME_MACHINE}-${UNAME_SYSTEM}-${UNAME_RELEASE} + exit 0 ;; + *:Plan9:*:*) + # "uname -m" is not consistent, so use $cputype instead. 386 + # is converted to i386 for consistency with other x86 + # operating systems. + if test "$cputype" = "386"; then + UNAME_MACHINE=i386 + else + UNAME_MACHINE="$cputype" + fi + echo ${UNAME_MACHINE}-unknown-plan9 + exit 0 ;; + *:TOPS-10:*:*) + echo pdp10-unknown-tops10 + exit 0 ;; + *:TENEX:*:*) + echo pdp10-unknown-tenex + exit 0 ;; + KS10:TOPS-20:*:* | KL10:TOPS-20:*:* | TYPE4:TOPS-20:*:*) + echo pdp10-dec-tops20 + exit 0 ;; + XKL-1:TOPS-20:*:* | TYPE5:TOPS-20:*:*) + echo pdp10-xkl-tops20 + exit 0 ;; + *:TOPS-20:*:*) + echo pdp10-unknown-tops20 + exit 0 ;; + *:ITS:*:*) + echo pdp10-unknown-its + exit 0 ;; + SEI:*:*:SEIUX) + echo mips-sei-seiux${UNAME_RELEASE} + exit 0 ;; + *:DragonFly:*:*) + echo ${UNAME_MACHINE}-unknown-dragonfly`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'` + exit 0 ;; + *:*VMS:*:*) + UNAME_MACHINE=`(uname -p) 2>/dev/null` + case "${UNAME_MACHINE}" in + A*) echo alpha-dec-vms && exit 0 ;; + I*) echo ia64-dec-vms && exit 0 ;; + V*) echo vax-dec-vms && exit 0 ;; + esac +esac + +#echo '(No uname command or uname output not recognized.)' 1>&2 +#echo "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" 1>&2 + +eval $set_cc_for_build +cat >$dummy.c < +# include +#endif +main () +{ +#if defined (sony) +#if defined (MIPSEB) + /* BFD wants "bsd" instead of "newsos". Perhaps BFD should be changed, + I don't know.... */ + printf ("mips-sony-bsd\n"); exit (0); +#else +#include + printf ("m68k-sony-newsos%s\n", +#ifdef NEWSOS4 + "4" +#else + "" +#endif + ); exit (0); +#endif +#endif + +#if defined (__arm) && defined (__acorn) && defined (__unix) + printf ("arm-acorn-riscix"); exit (0); +#endif + +#if defined (hp300) && !defined (hpux) + printf ("m68k-hp-bsd\n"); exit (0); +#endif + +#if defined (NeXT) +#if !defined (__ARCHITECTURE__) +#define __ARCHITECTURE__ "m68k" +#endif + int version; + version=`(hostinfo | sed -n 's/.*NeXT Mach \([0-9]*\).*/\1/p') 2>/dev/null`; + if (version < 4) + printf ("%s-next-nextstep%d\n", __ARCHITECTURE__, version); + else + printf ("%s-next-openstep%d\n", __ARCHITECTURE__, version); + exit (0); +#endif + +#if defined (MULTIMAX) || defined (n16) +#if defined (UMAXV) + printf ("ns32k-encore-sysv\n"); exit (0); +#else +#if defined (CMU) + printf ("ns32k-encore-mach\n"); exit (0); +#else + printf ("ns32k-encore-bsd\n"); exit (0); +#endif +#endif +#endif + +#if defined (__386BSD__) + printf ("i386-pc-bsd\n"); exit (0); +#endif + +#if defined (sequent) +#if defined (i386) + printf ("i386-sequent-dynix\n"); exit (0); +#endif +#if defined (ns32000) + printf ("ns32k-sequent-dynix\n"); exit (0); +#endif +#endif + +#if defined (_SEQUENT_) + struct utsname un; + + uname(&un); + + if (strncmp(un.version, "V2", 2) == 0) { + printf ("i386-sequent-ptx2\n"); exit (0); + } + if (strncmp(un.version, "V1", 2) == 0) { /* XXX is V1 correct? */ + printf ("i386-sequent-ptx1\n"); exit (0); + } + printf ("i386-sequent-ptx\n"); exit (0); + +#endif + +#if defined (vax) +# if !defined (ultrix) +# include +# if defined (BSD) +# if BSD == 43 + printf ("vax-dec-bsd4.3\n"); exit (0); +# else +# if BSD == 199006 + printf ("vax-dec-bsd4.3reno\n"); exit (0); +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# endif +# else + printf ("vax-dec-bsd\n"); exit (0); +# endif +# else + printf ("vax-dec-ultrix\n"); exit (0); +# endif +#endif + +#if defined (alliant) && defined (i860) + printf ("i860-alliant-bsd\n"); exit (0); +#endif + + exit (1); +} +EOF + +$CC_FOR_BUILD -o $dummy $dummy.c 2>/dev/null && $dummy && exit 0 + +# Apollos put the system type in the environment. + +test -d /usr/apollo && { echo ${ISP}-apollo-${SYSTYPE}; exit 0; } + +# Convex versions that predate uname can use getsysinfo(1) + +if [ -x /usr/convex/getsysinfo ] +then + case `getsysinfo -f cpu_type` in + c1*) + echo c1-convex-bsd + exit 0 ;; + c2*) + if getsysinfo -f scalar_acc + then echo c32-convex-bsd + else echo c2-convex-bsd + fi + exit 0 ;; + c34*) + echo c34-convex-bsd + exit 0 ;; + c38*) + echo c38-convex-bsd + exit 0 ;; + c4*) + echo c4-convex-bsd + exit 0 ;; + esac +fi + +cat >&2 < in order to provide the needed +information to handle your system. + +config.guess timestamp = $timestamp + +uname -m = `(uname -m) 2>/dev/null || echo unknown` +uname -r = `(uname -r) 2>/dev/null || echo unknown` +uname -s = `(uname -s) 2>/dev/null || echo unknown` +uname -v = `(uname -v) 2>/dev/null || echo unknown` + +/usr/bin/uname -p = `(/usr/bin/uname -p) 2>/dev/null` +/bin/uname -X = `(/bin/uname -X) 2>/dev/null` + +hostinfo = `(hostinfo) 2>/dev/null` +/bin/universe = `(/bin/universe) 2>/dev/null` +/usr/bin/arch -k = `(/usr/bin/arch -k) 2>/dev/null` +/bin/arch = `(/bin/arch) 2>/dev/null` +/usr/bin/oslevel = `(/usr/bin/oslevel) 2>/dev/null` +/usr/convex/getsysinfo = `(/usr/convex/getsysinfo) 2>/dev/null` + +UNAME_MACHINE = ${UNAME_MACHINE} +UNAME_RELEASE = ${UNAME_RELEASE} +UNAME_SYSTEM = ${UNAME_SYSTEM} +UNAME_VERSION = ${UNAME_VERSION} +EOF + +exit 1 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "timestamp='" +# time-stamp-format: "%:y-%02m-%02d" +# time-stamp-end: "'" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h new file mode 100755 index 00000000..78a8d9c0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h @@ -0,0 +1,86 @@ +/* config.h. Generated by configure. */ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the `erand48' function. */ +#define HAVE_ERAND48 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_INTTYPES_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_MALLOC_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_MEMORY_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDINT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STDLIB_H 1 + +/* Define to 1 if you have the `strchr' function. */ +#define HAVE_STRCHR 1 + +/* Define to 1 if you have the `strdup' function. */ +#define HAVE_STRDUP 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STRINGS_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_STRING_H 1 + +/* Define to 1 if you have the `strstr' function. */ +#define HAVE_STRSTR 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_STAT_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_SYS_TYPES_H 1 + +/* Define to 1 if you have the header file. */ +#define HAVE_UNISTD_H 1 + +/* Name of package */ +#define PACKAGE "ViennaRNA" + +/* Define to the address where bug reports for this package should be sent. */ +#define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" + +/* Define to the full name of this package. */ +#define PACKAGE_NAME "ViennaRNA" + +/* Define to the full name and version of this package. */ +#define PACKAGE_STRING "ViennaRNA 1.6" + +/* Define to the one symbol short name of this package. */ +#define PACKAGE_TARNAME "ViennaRNA" + +/* Define to the version of this package. */ +#define PACKAGE_VERSION "1.6" + +/* Define to 1 if you have the ANSI C header files. */ +#define STDC_HEADERS 1 + +/* only for gcc */ +#define UNUSED __attribute__ ((unused)) + +/* Version number of package */ +#define VERSION "1.6" + +/* Define if using the dmalloc debugging malloc package */ +/* #undef WITH_DMALLOC */ + +/* Define to empty if `const' does not conform to ANSI C. */ +/* #undef const */ + +/* Define to `__inline__' or `__inline' if that's what the C compiler + calls it, or to nothing if 'inline' is not supported under any name. */ +#ifndef __cplusplus +/* #undef inline */ +#endif + +/* Define to `unsigned' if does not define. */ +/* #undef size_t */ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h.in new file mode 100755 index 00000000..361112b2 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.h.in @@ -0,0 +1,85 @@ +/* config.h.in. Generated from configure.in by autoheader. */ + +/* Define to 1 if you have the `erand48' function. */ +#undef HAVE_ERAND48 + +/* Define to 1 if you have the header file. */ +#undef HAVE_INTTYPES_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_MALLOC_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_MEMORY_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDINT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STDLIB_H + +/* Define to 1 if you have the `strchr' function. */ +#undef HAVE_STRCHR + +/* Define to 1 if you have the `strdup' function. */ +#undef HAVE_STRDUP + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRINGS_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_STRING_H + +/* Define to 1 if you have the `strstr' function. */ +#undef HAVE_STRSTR + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_STAT_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_SYS_TYPES_H + +/* Define to 1 if you have the header file. */ +#undef HAVE_UNISTD_H + +/* Name of package */ +#undef PACKAGE + +/* Define to the address where bug reports for this package should be sent. */ +#undef PACKAGE_BUGREPORT + +/* Define to the full name of this package. */ +#undef PACKAGE_NAME + +/* Define to the full name and version of this package. */ +#undef PACKAGE_STRING + +/* Define to the one symbol short name of this package. */ +#undef PACKAGE_TARNAME + +/* Define to the version of this package. */ +#undef PACKAGE_VERSION + +/* Define to 1 if you have the ANSI C header files. */ +#undef STDC_HEADERS + +/* only for gcc */ +#undef UNUSED + +/* Version number of package */ +#undef VERSION + +/* Define if using the dmalloc debugging malloc package */ +#undef WITH_DMALLOC + +/* Define to empty if `const' does not conform to ANSI C. */ +#undef const + +/* Define to `__inline__' or `__inline' if that's what the C compiler + calls it, or to nothing if 'inline' is not supported under any name. */ +#ifndef __cplusplus +#undef inline +#endif + +/* Define to `unsigned' if does not define. */ +#undef size_t diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.log b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.log new file mode 100755 index 00000000..4edb2e45 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.log @@ -0,0 +1,625 @@ +This file contains any messages produced by compilers while +running configure, to aid debugging if configure makes a mistake. + +It was created by ViennaRNA configure 1.6, which was +generated by GNU Autoconf 2.59. Invocation command line was + + $ ./configure + +## --------- ## +## Platform. ## +## --------- ## + +hostname = mcluster02 +uname -m = x86_64 +uname -r = 2.6.9-34.ELsmp +uname -s = Linux +uname -v = #1 SMP Fri Feb 24 16:56:28 EST 2006 + +/usr/bin/uname -p = unknown +/bin/uname -X = unknown + +/bin/arch = x86_64 +/usr/bin/arch -k = unknown +/usr/convex/getsysinfo = unknown +hostinfo = unknown +/bin/machine = unknown +/usr/bin/oslevel = unknown +/bin/universe = unknown + +PATH: /storage/appl/n1ge6u7/bin/lx24-amd64 +PATH: /opt/sun/n1gc/bin +PATH: /usr/local/bin +PATH: /bin +PATH: /usr/bin +PATH: /opt/c3-4/ +PATH: /usr/X11R6/bin +PATH: /usr/local/bin +PATH: /usr/local/bin/X11R5 +PATH: /usr/local/X11R5/bin +PATH: /usr/X11R6/bin +PATH: /home/rabani/Develop/perl/GeneXPress +PATH: /home/rabani/Develop/perl/Genome +PATH: /home/rabani/Develop/perl/Lib +PATH: /home/rabani/Develop/perl/Parsers +PATH: /home/rabani/Develop/perl/RNA +PATH: /home/rabani/Develop/perl/Sequence +PATH: /home/rabani/Develop/perl/System +PATH: /home/rabani/Develop/perl/Web +PATH: /home/rabani/Develop/perl/Web/DataDir +PATH: /home/rabani/Develop/genie_release64/Programs +PATH: /storage/appl/matlab14.3/bin +PATH: /home/rabani + + +## ----------- ## +## Core tests. ## +## ----------- ## + +configure:1368: checking for a BSD-compatible install +configure:1423: result: /usr/bin/install -c +configure:1434: checking whether build environment is sane +configure:1477: result: yes +configure:1542: checking for gawk +configure:1558: found /bin/gawk +configure:1568: result: gawk +configure:1578: checking whether make sets $(MAKE) +configure:1598: result: yes +configure:1767: checking if malloc debugging is wanted +configure:1788: result: no +configure:1836: checking build system type +configure:1854: result: x86_64-unknown-linux-gnu +configure:1862: checking host system type +configure:1876: result: x86_64-unknown-linux-gnu +configure:1931: checking for gcc +configure:1947: found /usr/bin/gcc +configure:1957: result: gcc +configure:2201: checking for C compiler version +configure:2204: gcc --version &5 +gcc (GCC) 3.4.5 20051201 (Red Hat 3.4.5-2) +Copyright (C) 2004 Free Software Foundation, Inc. +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. + +configure:2207: $? = 0 +configure:2209: gcc -v &5 +Reading specs from /usr/lib/gcc/x86_64-redhat-linux/3.4.5/specs +Configured with: ../configure --prefix=/usr --mandir=/usr/share/man --infodir=/usr/share/info --enable-shared --enable-threads=posix --disable-checking --with-system-zlib --enable-__cxa_atexit --disable-libunwind-exceptions --enable-java-awt=gtk --host=x86_64-redhat-linux +Thread model: posix +gcc version 3.4.5 20051201 (Red Hat 3.4.5-2) +configure:2212: $? = 0 +configure:2214: gcc -V &5 +gcc: `-V' option must have argument +configure:2217: $? = 1 +configure:2240: checking for C compiler default output file name +configure:2243: gcc conftest.c >&5 +configure:2246: $? = 0 +configure:2292: result: a.out +configure:2297: checking whether the C compiler works +configure:2303: ./a.out +configure:2306: $? = 0 +configure:2323: result: yes +configure:2330: checking whether we are cross compiling +configure:2332: result: no +configure:2335: checking for suffix of executables +configure:2337: gcc -o conftest conftest.c >&5 +configure:2340: $? = 0 +configure:2365: result: +configure:2371: checking for suffix of object files +configure:2392: gcc -c conftest.c >&5 +configure:2395: $? = 0 +configure:2417: result: o +configure:2421: checking whether we are using the GNU C compiler +configure:2445: gcc -c conftest.c >&5 +configure:2451: $? = 0 +configure:2455: test -z + || test ! -s conftest.err +configure:2458: $? = 0 +configure:2461: test -s conftest.o +configure:2464: $? = 0 +configure:2477: result: yes +configure:2483: checking whether gcc accepts -g +configure:2504: gcc -c -g conftest.c >&5 +configure:2510: $? = 0 +configure:2514: test -z + || test ! -s conftest.err +configure:2517: $? = 0 +configure:2520: test -s conftest.o +configure:2523: $? = 0 +configure:2534: result: yes +configure:2551: checking for gcc option to accept ANSI C +configure:2621: gcc -c -g -O2 conftest.c >&5 +configure:2627: $? = 0 +configure:2631: test -z + || test ! -s conftest.err +configure:2634: $? = 0 +configure:2637: test -s conftest.o +configure:2640: $? = 0 +configure:2658: result: none needed +configure:2676: gcc -c -g -O2 conftest.c >&5 +conftest.c:2: error: syntax error before "me" +configure:2682: $? = 1 +configure: failed program was: +| #ifndef __cplusplus +| choke me +| #endif +configure:2826: checking for style of include used by make +configure:2854: result: GNU +configure:2882: checking dependency style of gcc +configure:2972: result: gcc3 +configure:3015: checking for a BSD-compatible install +configure:3070: result: /usr/bin/install -c +configure:3122: checking for ranlib +configure:3138: found /usr/bin/ranlib +configure:3149: result: ranlib +configure:3164: checking for perl +configure:3182: found /usr/bin/perl +configure:3194: result: /usr/bin/perl +configure:3297: checking how to run the C preprocessor +configure:3332: gcc -E conftest.c +configure:3338: $? = 0 +configure:3370: gcc -E conftest.c +conftest.c:12:28: ac_nonexistent.h: No such file or directory +configure:3376: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "ViennaRNA" +| #define PACKAGE_TARNAME "ViennaRNA" +| #define PACKAGE_VERSION "1.6" +| #define PACKAGE_STRING "ViennaRNA 1.6" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "ViennaRNA" +| #define VERSION "1.6" +| #define UNUSED __attribute__ ((unused)) +| /* end confdefs.h. */ +| #include +configure:3415: result: gcc -E +configure:3439: gcc -E conftest.c +configure:3445: $? = 0 +configure:3477: gcc -E conftest.c +conftest.c:12:28: ac_nonexistent.h: No such file or directory +configure:3483: $? = 1 +configure: failed program was: +| /* confdefs.h. */ +| +| #define PACKAGE_NAME "ViennaRNA" +| #define PACKAGE_TARNAME "ViennaRNA" +| #define PACKAGE_VERSION "1.6" +| #define PACKAGE_STRING "ViennaRNA 1.6" +| #define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +| #define PACKAGE "ViennaRNA" +| #define VERSION "1.6" +| #define UNUSED __attribute__ ((unused)) +| /* end confdefs.h. */ +| #include +configure:3527: checking for egrep +configure:3537: result: grep -E +configure:3542: checking for ANSI C header files +configure:3567: gcc -c -g -O2 conftest.c >&5 +configure:3573: $? = 0 +configure:3577: test -z + || test ! -s conftest.err +configure:3580: $? = 0 +configure:3583: test -s conftest.o +configure:3586: $? = 0 +configure:3675: gcc -o conftest -g -O2 conftest.c >&5 +configure:3678: $? = 0 +configure:3680: ./conftest +configure:3683: $? = 0 +configure:3698: result: yes +configure:3722: checking for sys/types.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for sys/stat.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for stdlib.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for string.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for memory.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for strings.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for inttypes.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for stdint.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3722: checking for unistd.h +configure:3738: gcc -c -g -O2 conftest.c >&5 +configure:3744: $? = 0 +configure:3748: test -z + || test ! -s conftest.err +configure:3751: $? = 0 +configure:3754: test -s conftest.o +configure:3757: $? = 0 +configure:3768: result: yes +configure:3796: checking malloc.h usability +configure:3808: gcc -c -g -O2 conftest.c >&5 +configure:3814: $? = 0 +configure:3818: test -z + || test ! -s conftest.err +configure:3821: $? = 0 +configure:3824: test -s conftest.o +configure:3827: $? = 0 +configure:3837: result: yes +configure:3841: checking malloc.h presence +configure:3851: gcc -E conftest.c +configure:3857: $? = 0 +configure:3877: result: yes +configure:3912: checking for malloc.h +configure:3919: result: yes +configure:3787: checking for strings.h +configure:3792: result: yes +configure:3787: checking for unistd.h +configure:3792: result: yes +configure:3933: checking for an ANSI C-conforming const +configure:4000: gcc -c -g -O2 conftest.c >&5 +configure:4006: $? = 0 +configure:4010: test -z + || test ! -s conftest.err +configure:4013: $? = 0 +configure:4016: test -s conftest.o +configure:4019: $? = 0 +configure:4030: result: yes +configure:4040: checking for size_t +configure:4064: gcc -c -g -O2 conftest.c >&5 +configure:4070: $? = 0 +configure:4074: test -z + || test ! -s conftest.err +configure:4077: $? = 0 +configure:4080: test -s conftest.o +configure:4083: $? = 0 +configure:4094: result: yes +configure:4106: checking for inline +configure:4127: gcc -c -g -O2 conftest.c >&5 +configure:4133: $? = 0 +configure:4137: test -z + || test ! -s conftest.err +configure:4140: $? = 0 +configure:4143: test -s conftest.o +configure:4146: $? = 0 +configure:4158: result: inline +configure:4185: checking for strdup +configure:4242: gcc -o conftest -g -O2 conftest.c >&5 +conftest.c:49: warning: conflicting types for built-in function 'strdup' +configure:4248: $? = 0 +configure:4252: test -z + || test ! -s conftest.err +configure:4255: $? = 0 +configure:4258: test -s conftest +configure:4261: $? = 0 +configure:4273: result: yes +configure:4185: checking for strstr +configure:4242: gcc -o conftest -g -O2 conftest.c >&5 +conftest.c:50: warning: conflicting types for built-in function 'strstr' +configure:4248: $? = 0 +configure:4252: test -z + || test ! -s conftest.err +configure:4255: $? = 0 +configure:4258: test -s conftest +configure:4261: $? = 0 +configure:4273: result: yes +configure:4185: checking for strchr +configure:4242: gcc -o conftest -g -O2 conftest.c >&5 +conftest.c:51: warning: conflicting types for built-in function 'strchr' +configure:4248: $? = 0 +configure:4252: test -z + || test ! -s conftest.err +configure:4255: $? = 0 +configure:4258: test -s conftest +configure:4261: $? = 0 +configure:4273: result: yes +configure:4185: checking for erand48 +configure:4242: gcc -o conftest -g -O2 conftest.c >&5 +configure:4248: $? = 0 +configure:4252: test -z + || test ! -s conftest.err +configure:4255: $? = 0 +configure:4258: test -s conftest +configure:4261: $? = 0 +configure:4273: result: yes +configure:4423: creating ./config.status + +## ---------------------- ## +## Running config.status. ## +## ---------------------- ## + +This file was extended by ViennaRNA config.status 1.6, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = + CONFIG_HEADERS = + CONFIG_LINKS = + CONFIG_COMMANDS = + $ ./config.status + +on mcluster02 + +config.status:731: creating Makefile +config.status:731: creating ViennaRNA.spec +config.status:731: creating Utils/Makefile +config.status:731: creating Progs/Makefile +config.status:731: creating lib/Makefile +config.status:731: creating man/Makefile +config.status:731: creating Cluster/Makefile +config.status:731: creating H/Makefile +config.status:731: creating Perl/Makefile +config.status:731: creating man/RNAheat.1 +config.status:731: creating man/RNAsubopt.1 +config.status:731: creating man/RNAdistance.1 +config.status:731: creating man/RNAinverse.1 +config.status:731: creating man/RNAeval.1 +config.status:731: creating man/RNAfold.1 +config.status:731: creating man/RNApdist.1 +config.status:731: creating man/RNAplot.1 +config.status:731: creating man/RNALfold.1 +config.status:731: creating man/RNAalifold.1 +config.status:731: creating man/RNAduplex.1 +config.status:731: creating man/RNAcofold.1 +config.status:731: creating man/RNAplfold.1 +config.status:835: creating config.h +config.status:957: config.h is unchanged +config.status:1137: executing depfiles commands +configure:5796: configuring in RNAforester +configure:5913: running /bin/sh './configure' --prefix=/usr/local --cache-file=/dev/null --srcdir=. +configure:5796: configuring in Kinfold +configure:5913: running /bin/sh './configure' --prefix=/usr/local --cache-file=/dev/null --srcdir=. +configure:5949: +Configure successful with the following options: + + Perl Extension: yes + Analyse{Dists,Seqs}: no + Kinfold: yes + RNAforester: yes + +Files will be installed in the following directories: + + Executables: /usr/local/bin + Libraries: /usr/local/lib + Header files: /usr/local/include + Extra Data: /usr/local/share + Man pages: /usr/local/man + + +## ---------------- ## +## Cache variables. ## +## ---------------- ## + +ac_cv_build=x86_64-unknown-linux-gnu +ac_cv_build_alias=x86_64-unknown-linux-gnu +ac_cv_c_compiler_gnu=yes +ac_cv_c_const=yes +ac_cv_c_inline=inline +ac_cv_env_CC_set= +ac_cv_env_CC_value= +ac_cv_env_CFLAGS_set= +ac_cv_env_CFLAGS_value= +ac_cv_env_CPPFLAGS_set= +ac_cv_env_CPPFLAGS_value= +ac_cv_env_CPP_set= +ac_cv_env_CPP_value= +ac_cv_env_LDFLAGS_set= +ac_cv_env_LDFLAGS_value= +ac_cv_env_build_alias_set= +ac_cv_env_build_alias_value= +ac_cv_env_host_alias_set= +ac_cv_env_host_alias_value= +ac_cv_env_target_alias_set= +ac_cv_env_target_alias_value= +ac_cv_exeext= +ac_cv_func_erand48=yes +ac_cv_func_strchr=yes +ac_cv_func_strdup=yes +ac_cv_func_strstr=yes +ac_cv_header_inttypes_h=yes +ac_cv_header_malloc_h=yes +ac_cv_header_memory_h=yes +ac_cv_header_stdc=yes +ac_cv_header_stdint_h=yes +ac_cv_header_stdlib_h=yes +ac_cv_header_string_h=yes +ac_cv_header_strings_h=yes +ac_cv_header_sys_stat_h=yes +ac_cv_header_sys_types_h=yes +ac_cv_header_unistd_h=yes +ac_cv_host=x86_64-unknown-linux-gnu +ac_cv_host_alias=x86_64-unknown-linux-gnu +ac_cv_objext=o +ac_cv_path_PerlCmd=/usr/bin/perl +ac_cv_path_install='/usr/bin/install -c' +ac_cv_prog_AWK=gawk +ac_cv_prog_CPP='gcc -E' +ac_cv_prog_ac_ct_CC=gcc +ac_cv_prog_ac_ct_RANLIB=ranlib +ac_cv_prog_cc_g=yes +ac_cv_prog_cc_stdc= +ac_cv_prog_egrep='grep -E' +ac_cv_prog_make_make_set=yes +ac_cv_type_size_t=yes +am_cv_CC_dependencies_compiler_type=gcc3 + +## ----------------- ## +## Output variables. ## +## ----------------- ## + +ACLOCAL='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run aclocal-1.9' +AMDEPBACKSLASH='\' +AMDEP_FALSE='#' +AMDEP_TRUE='' +AMTAR='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run tar' +AUTOCONF='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoconf' +AUTOHEADER='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoheader' +AUTOMAKE='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run automake-1.9' +AWK='gawk' +CC='gcc' +CCDEPMODE='depmode=gcc3' +CFLAGS='-g -O2' +CPP='gcc -E' +CPPFLAGS='' +CYGPATH_W='echo' +DEFS='-DHAVE_CONFIG_H' +DEPDIR='.deps' +ECHO_C='' +ECHO_N='-n' +ECHO_T='' +EGREP='grep -E' +EXEEXT='' +INSTALL_DATA='${INSTALL} -m 644' +INSTALL_PROGRAM='${INSTALL}' +INSTALL_SCRIPT='${INSTALL}' +INSTALL_STRIP_PROGRAM='${SHELL} $(install_sh) -c -s' +ISODATE='2006-06-13' +LDFLAGS='' +LIBOBJS='' +LIBS='' +LTLIBOBJS='' +MAKEINFO='${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run makeinfo' +MAKE_CLUSTER_FALSE='' +MAKE_CLUSTER_TRUE='#' +MAKE_FORESTER_FALSE='#' +MAKE_FORESTER_TRUE='' +MAKE_KINFOLD_FALSE='#' +MAKE_KINFOLD_TRUE='' +MAKE_PERL_EXT_FALSE='#' +MAKE_PERL_EXT_TRUE='' +OBJEXT='o' +PACKAGE='ViennaRNA' +PACKAGE_BUGREPORT='rna@tbi.univie.ac.at' +PACKAGE_NAME='ViennaRNA' +PACKAGE_STRING='ViennaRNA 1.6' +PACKAGE_TARNAME='ViennaRNA' +PACKAGE_VERSION='1.6' +PATH_SEPARATOR=':' +PerlCmd='/usr/bin/perl' +RANLIB='ranlib' +SET_MAKE='' +SHELL='/bin/sh' +STRIP='' +VERSION='1.6' +ac_ct_CC='gcc' +ac_ct_RANLIB='ranlib' +ac_ct_STRIP='' +am__fastdepCC_FALSE='#' +am__fastdepCC_TRUE='' +am__include='include' +am__leading_dot='.' +am__quote='' +am__tar='${AMTAR} chof - "$$tardir"' +am__untar='${AMTAR} xf -' +bindir='${exec_prefix}/bin' +build='x86_64-unknown-linux-gnu' +build_alias='' +build_cpu='x86_64' +build_os='linux-gnu' +build_vendor='unknown' +datadir='${prefix}/share' +exec_prefix='${prefix}' +host='x86_64-unknown-linux-gnu' +host_alias='' +host_cpu='x86_64' +host_os='linux-gnu' +host_vendor='unknown' +includedir='${prefix}/include' +infodir='${prefix}/info' +install_sh='/home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/install-sh' +libdir='${exec_prefix}/lib' +libexecdir='${exec_prefix}/libexec' +localstatedir='${prefix}/var' +mandir='${prefix}/man' +mkdir_p='mkdir -p --' +oldincludedir='/usr/include' +prefix='/usr/local' +program_transform_name='s,x,x,' +sbindir='${exec_prefix}/sbin' +sharedstatedir='${prefix}/com' +subdirs=' RNAforester Kinfold' +sysconfdir='${prefix}/etc' +target_alias='' + +## ----------- ## +## confdefs.h. ## +## ----------- ## + +#define HAVE_ERAND48 1 +#define HAVE_INTTYPES_H 1 +#define HAVE_MALLOC_H 1 +#define HAVE_MEMORY_H 1 +#define HAVE_STDINT_H 1 +#define HAVE_STDLIB_H 1 +#define HAVE_STRCHR 1 +#define HAVE_STRDUP 1 +#define HAVE_STRINGS_H 1 +#define HAVE_STRINGS_H 1 +#define HAVE_STRING_H 1 +#define HAVE_STRSTR 1 +#define HAVE_SYS_STAT_H 1 +#define HAVE_SYS_TYPES_H 1 +#define HAVE_UNISTD_H 1 +#define HAVE_UNISTD_H 1 +#define PACKAGE "ViennaRNA" +#define PACKAGE_BUGREPORT "rna@tbi.univie.ac.at" +#define PACKAGE_NAME "ViennaRNA" +#define PACKAGE_STRING "ViennaRNA 1.6" +#define PACKAGE_TARNAME "ViennaRNA" +#define PACKAGE_VERSION "1.6" +#define STDC_HEADERS 1 +#define UNUSED __attribute__ ((unused)) +#define VERSION "1.6" + +configure: exit 0 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.status b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.status new file mode 100755 index 00000000..07739d49 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.status @@ -0,0 +1,1228 @@ +#! /bin/sh +# Generated by configure. +# Run this file to recreate the current configuration. +# Compiler output produced by configure, useful for debugging +# configure, is in config.log if it exists. + +debug=false +ac_cs_recheck=false +ac_cs_silent=false +SHELL=${CONFIG_SHELL-/bin/sh} +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-) + sed '=' <$as_myself | + sed ' + N + s,$,-, + : loop + s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3, + t loop + s,-$,, + s,^['$as_cr_digits']*\n,, + ' >$as_me.lineno && + chmod +x $as_me.lineno || + { { echo "$as_me:$LINENO: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&5 +echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2;} + { (exit 1); exit 1; }; } + + # Don't try to exec as it changes $[0], causing all sort of problems + # (the dirname of $[0] is not the place where we might find the + # original and so on. Autoconf is especially sensible to this). + . ./$as_me.lineno + # Exit status is that of the last command. + exit +} + + +case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in + *c*,-n*) ECHO_N= ECHO_C=' +' ECHO_T=' ' ;; + *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;; + *) ECHO_N= ECHO_C='\c' ECHO_T= ;; +esac + +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +rm -f conf$$ conf$$.exe conf$$.file +echo >conf$$.file +if ln -s conf$$.file conf$$ 2>/dev/null; then + # We could just check for DJGPP; but this test a) works b) is more generic + # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04). + if test -f conf$$.exe; then + # Don't use ln at all; we don't have any links + as_ln_s='cp -p' + else + as_ln_s='ln -s' + fi +elif ln conf$$.file conf$$ 2>/dev/null; then + as_ln_s=ln +else + as_ln_s='cp -p' +fi +rm -f conf$$ conf$$.exe conf$$.file + +if mkdir -p . 2>/dev/null; then + as_mkdir_p=: +else + test -d ./-p && rmdir ./-p + as_mkdir_p=false +fi + +as_executable_p="test -f" + +# Sed expression to map a string onto a valid CPP name. +as_tr_cpp="eval sed 'y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g'" + +# Sed expression to map a string onto a valid variable name. +as_tr_sh="eval sed 'y%*+%pp%;s%[^_$as_cr_alnum]%_%g'" + + +# IFS +# We need space, tab and new line, in precisely that order. +as_nl=' +' +IFS=" $as_nl" + +# CDPATH. +$as_unset CDPATH + +exec 6>&1 + +# Open the log real soon, to keep \$[0] and so on meaningful, and to +# report actual input values of CONFIG_FILES etc. instead of their +# values after options handling. Logging --version etc. is OK. +exec 5>>config.log +{ + echo + sed 'h;s/./-/g;s/^.../## /;s/...$/ ##/;p;x;p;x' <<_ASBOX +## Running $as_me. ## +_ASBOX +} >&5 +cat >&5 <<_CSEOF + +This file was extended by ViennaRNA $as_me 1.6, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +config_files=" Makefile ViennaRNA.spec Utils/Makefile Progs/Makefile lib/Makefile man/Makefile Cluster/Makefile H/Makefile Perl/Makefile man/RNAheat.1 man/RNAsubopt.1 man/RNAdistance.1 man/RNAinverse.1 man/RNAeval.1 man/RNAfold.1 man/RNApdist.1 man/RNAplot.1 man/RNALfold.1 man/RNAalifold.1 man/RNAduplex.1 man/RNAcofold.1 man/RNAplfold.1" +config_headers=" config.h" +config_commands=" depfiles" + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +ac_cs_version="\ +ViennaRNA config.status 1.6 +configured by ./configure, generated by GNU Autoconf 2.59, + with options \"\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=. +INSTALL="/usr/bin/install -c" +# If no file are specified by the user, then we need to provide default +# value. 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Set only those that are not. +# We use the long form for the default assignment because of an extremely +# bizarre bug on SunOS 4.1.3. +if $ac_need_defaults; then + test "${CONFIG_FILES+set}" = set || CONFIG_FILES=$config_files + test "${CONFIG_HEADERS+set}" = set || CONFIG_HEADERS=$config_headers + test "${CONFIG_COMMANDS+set}" = set || CONFIG_COMMANDS=$config_commands +fi + +# Have a temporary directory for convenience. Make it in the build tree +# simply because there is no reason to put it here, and in addition, +# creating and moving files from /tmp can sometimes cause problems. +# Create a temporary directory, and hook for its removal unless debugging. +$debug || +{ + trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0 + trap '{ (exit 1); exit 1; }' 1 2 13 15 +} + +# Create a (secure) tmp directory for tmp files. + +{ + tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` && + test -n "$tmp" && test -d "$tmp" +} || +{ + tmp=./confstat$$-$RANDOM + (umask 077 && mkdir $tmp) +} || +{ + echo "$me: cannot create a temporary directory in ." >&2 + { (exit 1); exit 1; } +} + + +# +# CONFIG_FILES section. +# + +# No need to generate the scripts if there are no CONFIG_FILES. +# This happens for instance when ./config.status config.h +if test -n "$CONFIG_FILES"; then + # Protect against being on the right side of a sed subst in config.status. + sed 's/,@/@@/; s/@,/@@/; s/,;t t$/@;t t/; /@;t t$/s/[\\&,]/\\&/g; + s/@@/,@/; s/@@/@,/; s/@;t t$/,;t t/' >$tmp/subs.sed <<\CEOF +s,@SHELL@,/bin/sh,;t t +s,@PATH_SEPARATOR@,:,;t t +s,@PACKAGE_NAME@,ViennaRNA,;t t +s,@PACKAGE_TARNAME@,ViennaRNA,;t t +s,@PACKAGE_VERSION@,1.6,;t t +s,@PACKAGE_STRING@,ViennaRNA 1.6,;t t +s,@PACKAGE_BUGREPORT@,rna@tbi.univie.ac.at,;t t +s,@exec_prefix@,${prefix},;t t +s,@prefix@,/usr/local,;t t +s,@program_transform_name@,s,x,x,,;t t +s,@bindir@,${exec_prefix}/bin,;t t +s,@sbindir@,${exec_prefix}/sbin,;t t +s,@libexecdir@,${exec_prefix}/libexec,;t t +s,@datadir@,${prefix}/share,;t t +s,@sysconfdir@,${prefix}/etc,;t t +s,@sharedstatedir@,${prefix}/com,;t t +s,@localstatedir@,${prefix}/var,;t t +s,@libdir@,${exec_prefix}/lib,;t t +s,@includedir@,${prefix}/include,;t t +s,@oldincludedir@,/usr/include,;t t +s,@infodir@,${prefix}/info,;t t +s,@mandir@,${prefix}/man,;t t +s,@build_alias@,,;t t +s,@host_alias@,,;t t +s,@target_alias@,,;t t +s,@DEFS@,-DHAVE_CONFIG_H,;t t +s,@ECHO_C@,,;t t +s,@ECHO_N@,-n,;t t +s,@ECHO_T@,,;t t +s,@LIBS@,,;t t +s,@INSTALL_PROGRAM@,${INSTALL},;t t +s,@INSTALL_SCRIPT@,${INSTALL},;t t +s,@INSTALL_DATA@,${INSTALL} -m 644,;t t +s,@CYGPATH_W@,echo,;t t +s,@PACKAGE@,ViennaRNA,;t t +s,@VERSION@,1.6,;t t +s,@ACLOCAL@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run aclocal-1.9,;t t +s,@AUTOCONF@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoconf,;t t +s,@AUTOMAKE@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run automake-1.9,;t t +s,@AUTOHEADER@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run autoheader,;t t +s,@MAKEINFO@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run makeinfo,;t t +s,@install_sh@,/home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/install-sh,;t t +s,@STRIP@,,;t t +s,@ac_ct_STRIP@,,;t t +s,@INSTALL_STRIP_PROGRAM@,${SHELL} $(install_sh) -c -s,;t t +s,@mkdir_p@,mkdir -p --,;t t +s,@AWK@,gawk,;t t +s,@SET_MAKE@,,;t t +s,@am__leading_dot@,.,;t t +s,@AMTAR@,${SHELL} /home/rabani/Genie/Bin/ViennaRNA/ViennaRNA-1.6/missing --run tar,;t t +s,@am__tar@,${AMTAR} chof - "$$tardir",;t t +s,@am__untar@,${AMTAR} xf -,;t t +s,@ISODATE@,2006-06-13,;t t +s,@build@,x86_64-unknown-linux-gnu,;t t +s,@build_cpu@,x86_64,;t t +s,@build_vendor@,unknown,;t t +s,@build_os@,linux-gnu,;t t +s,@host@,x86_64-unknown-linux-gnu,;t t +s,@host_cpu@,x86_64,;t t +s,@host_vendor@,unknown,;t t +s,@host_os@,linux-gnu,;t t +s,@CC@,gcc,;t t +s,@CFLAGS@,-g -O2,;t t +s,@LDFLAGS@,,;t t +s,@CPPFLAGS@,,;t t +s,@ac_ct_CC@,gcc,;t t +s,@EXEEXT@,,;t t +s,@OBJEXT@,o,;t t +s,@DEPDIR@,.deps,;t t +s,@am__include@,include,;t t +s,@am__quote@,,;t t +s,@AMDEP_TRUE@,,;t t +s,@AMDEP_FALSE@,#,;t t +s,@AMDEPBACKSLASH@,\,;t t +s,@CCDEPMODE@,depmode=gcc3,;t t +s,@am__fastdepCC_TRUE@,,;t t +s,@am__fastdepCC_FALSE@,#,;t t +s,@RANLIB@,ranlib,;t t +s,@ac_ct_RANLIB@,ranlib,;t t +s,@PerlCmd@,/usr/bin/perl,;t t +s,@subdirs@, RNAforester Kinfold,;t t +s,@MAKE_PERL_EXT_TRUE@,,;t t +s,@MAKE_PERL_EXT_FALSE@,#,;t t +s,@MAKE_CLUSTER_TRUE@,#,;t t +s,@MAKE_CLUSTER_FALSE@,,;t t +s,@MAKE_FORESTER_TRUE@,,;t t +s,@MAKE_FORESTER_FALSE@,#,;t t +s,@MAKE_KINFOLD_TRUE@,,;t t +s,@MAKE_KINFOLD_FALSE@,#,;t t +s,@CPP@,gcc -E,;t t +s,@EGREP@,grep -E,;t t +s,@LIBOBJS@,,;t t +s,@LTLIBOBJS@,,;t t +CEOF + + # Split the substitutions into bite-sized pieces for seds with + # small command number limits, like on Digital OSF/1 and HP-UX. + ac_max_sed_lines=48 + ac_sed_frag=1 # Number of current file. + ac_beg=1 # First line for current file. + ac_end=$ac_max_sed_lines # Line after last line for current file. + ac_more_lines=: + ac_sed_cmds= + while $ac_more_lines; do + if test $ac_beg -gt 1; then + sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + else + sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag + fi + if test ! 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" + fi + configure_input=$configure_input"Generated from `echo $ac_file_in | + sed 's,.*/,,'` by configure." + + # First look for the input files in the build tree, otherwise in the + # src tree. + ac_file_inputs=`IFS=: + for f in $ac_file_in; do + case $f in + -) echo $tmp/stdin ;; + [\\/$]*) + # Absolute (can't be DOS-style, as IFS=:) + test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + echo "$f";; + *) # Relative + if test -f "$f"; then + # Build tree + echo "$f" + elif test -f "$srcdir/$f"; then + # Source tree + echo "$srcdir/$f" + else + # /dev/null tree + { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + fi;; + esac + done` || { (exit 1); exit 1; } + sed "/^[ ]*VPATH[ ]*=/{ +s/:*\$(srcdir):*/:/; +s/:*\${srcdir}:*/:/; +s/:*@srcdir@:*/:/; +s/^\([^=]*=[ ]*\):*/\1/; +s/:*$//; +s/^[^=]*=[ ]*$//; +} + +:t +/@[a-zA-Z_][a-zA-Z_0-9]*@/!b +s,@configure_input@,$configure_input,;t t +s,@srcdir@,$ac_srcdir,;t t +s,@abs_srcdir@,$ac_abs_srcdir,;t t +s,@top_srcdir@,$ac_top_srcdir,;t t +s,@abs_top_srcdir@,$ac_abs_top_srcdir,;t t +s,@builddir@,$ac_builddir,;t t +s,@abs_builddir@,$ac_abs_builddir,;t t +s,@top_builddir@,$ac_top_builddir,;t t +s,@abs_top_builddir@,$ac_abs_top_builddir,;t t +s,@INSTALL@,$ac_INSTALL,;t t +" $ac_file_inputs | (eval "$ac_sed_cmds") >$tmp/out + rm -f $tmp/stdin + if test x"$ac_file" != x-; then + mv $tmp/out $ac_file + else + cat $tmp/out + rm -f $tmp/out + fi + +done + +# +# CONFIG_HEADER section. +# + +# These sed commands are passed to sed as "A NAME B NAME C VALUE D", where +# NAME is the cpp macro being defined and VALUE is the value it is being given. +# +# ac_d sets the value in "#define NAME VALUE" lines. +ac_dA='s,^\([ ]*\)#\([ ]*define[ ][ ]*\)' +ac_dB='[ ].*$,\1#\2' +ac_dC=' ' +ac_dD=',;t' +# ac_u turns "#undef NAME" without trailing blanks into "#define NAME VALUE". +ac_uA='s,^\([ ]*\)#\([ ]*\)undef\([ ][ ]*\)' +ac_uB='$,\1#\2define\3' +ac_uC=' ' +ac_uD=',;t' + +for ac_file in : $CONFIG_HEADERS; do test "x$ac_file" = x: && continue + # Support "outfile[:infile[:infile...]]", defaulting infile="outfile.in". + case $ac_file in + - | *:- | *:-:* ) # input from stdin + cat >$tmp/stdin + ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + *:* ) ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;; + * ) ac_file_in=$ac_file.in ;; + esac + + test x"$ac_file" != x- && { echo "$as_me:$LINENO: creating $ac_file" >&5 +echo "$as_me: creating $ac_file" >&6;} + + # First look for the input files in the build tree, otherwise in the + # src tree. + ac_file_inputs=`IFS=: + for f in $ac_file_in; do + case $f in + -) echo $tmp/stdin ;; + [\\/$]*) + # Absolute (can't be DOS-style, as IFS=:) + test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + # Do quote $f, to prevent DOS paths from being IFS'd. + echo "$f";; + *) # Relative + if test -f "$f"; then + # Build tree + echo "$f" + elif test -f "$srcdir/$f"; then + # Source tree + echo "$srcdir/$f" + else + # /dev/null tree + { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5 +echo "$as_me: error: cannot find input file: $f" >&2;} + { (exit 1); exit 1; }; } + fi;; + esac + done` || { (exit 1); exit 1; } + # Remove the trailing spaces. + sed 's/[ ]*$//' $ac_file_inputs >$tmp/in + + # Handle all the #define templates only if necessary. + if grep "^[ ]*#[ ]*define" $tmp/in >/dev/null; then + # If there are no defines, we may have an empty if/fi + : + cat >$tmp/defines.sed <$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in + + fi # grep + + # Handle all the #undef templates + cat >$tmp/undefs.sed <$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in + + # Let's still pretend it is `configure' which instantiates (i.e., don't + # use $as_me), people would be surprised to read: + # /* config.h. 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We invoke sed twice because it is the + # simplest approach to changing $(DEPDIR) to its actual value in the + # expansion. + for file in `sed -n " + s/^$am__include $am__quote\(.*(DEPDIR).*\)$am__quote"'$/\1/p' <"$mf" | \ + sed -e 's/\$(DEPDIR)/'"$DEPDIR"'/g' -e 's/\$U/'"$U"'/g'`; do + # Make sure the directory exists. + test -f "$dirpart/$file" && continue + fdir=`(dirname "$file") 2>/dev/null || +$as_expr X"$file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$file" : 'X\(//\)[^/]' \| \ + X"$file" : 'X\(//\)$' \| \ + X"$file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p $dirpart/$fdir + else + as_dir=$dirpart/$fdir + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory $dirpart/$fdir" >&5 +echo "$as_me: error: cannot create directory $dirpart/$fdir" >&2;} + { (exit 1); exit 1; }; }; } + + # echo "creating $dirpart/$file" + echo '# dummy' > "$dirpart/$file" + done +done + ;; + esac +done + +{ (exit 0); exit 0; } diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.sub b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.sub new file mode 100755 index 00000000..ac6de986 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/config.sub @@ -0,0 +1,1552 @@ +#! /bin/sh +# Configuration validation subroutine script. +# Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, +# 2000, 2001, 2002, 2003, 2004 Free Software Foundation, Inc. + +timestamp='2004-06-24' + +# This file is (in principle) common to ALL GNU software. +# The presence of a machine in this file suggests that SOME GNU software +# can handle that machine. It does not imply ALL GNU software can. +# +# This file is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2 of the License, or +# (at your option) any later version. +# +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the +# GNU General Public License for more details. +# +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, +# Boston, MA 02111-1307, USA. + +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Please send patches to . Submit a context +# diff and a properly formatted ChangeLog entry. +# +# Configuration subroutine to validate and canonicalize a configuration type. +# Supply the specified configuration type as an argument. +# If it is invalid, we print an error message on stderr and exit with code 1. +# Otherwise, we print the canonical config type on stdout and succeed. + +# This file is supposed to be the same for all GNU packages +# and recognize all the CPU types, system types and aliases +# that are meaningful with *any* GNU software. +# Each package is responsible for reporting which valid configurations +# it does not support. The user should be able to distinguish +# a failure to support a valid configuration from a meaningless +# configuration. + +# The goal of this file is to map all the various variations of a given +# machine specification into a single specification in the form: +# CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM +# or in some cases, the newer four-part form: +# CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM +# It is wrong to echo any other type of specification. + +me=`echo "$0" | sed -e 's,.*/,,'` + +usage="\ +Usage: $0 [OPTION] CPU-MFR-OPSYS + $0 [OPTION] ALIAS + +Canonicalize a configuration name. + +Operation modes: + -h, --help print this help, then exit + -t, --time-stamp print date of last modification, then exit + -v, --version print version number, then exit + +Report bugs and patches to ." + +version="\ +GNU config.sub ($timestamp) + +Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004 +Free Software Foundation, Inc. + +This is free software; see the source for copying conditions. There is NO +warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE." + +help=" +Try \`$me --help' for more information." + +# Parse command line +while test $# -gt 0 ; do + case $1 in + --time-stamp | --time* | -t ) + echo "$timestamp" ; exit 0 ;; + --version | -v ) + echo "$version" ; exit 0 ;; + --help | --h* | -h ) + echo "$usage"; exit 0 ;; + -- ) # Stop option processing + shift; break ;; + - ) # Use stdin as input. + break ;; + -* ) + echo "$me: invalid option $1$help" + exit 1 ;; + + *local*) + # First pass through any local machine types. + echo $1 + exit 0;; + + * ) + break ;; + esac +done + +case $# in + 0) echo "$me: missing argument$help" >&2 + exit 1;; + 1) ;; + *) echo "$me: too many arguments$help" >&2 + exit 1;; +esac + +# Separate what the user gave into CPU-COMPANY and OS or KERNEL-OS (if any). +# Here we must recognize all the valid KERNEL-OS combinations. +maybe_os=`echo $1 | sed 's/^\(.*\)-\([^-]*-[^-]*\)$/\2/'` +case $maybe_os in + nto-qnx* | linux-gnu* | linux-dietlibc | linux-uclibc* | uclinux-uclibc* | uclinux-gnu* | \ + kfreebsd*-gnu* | knetbsd*-gnu* | netbsd*-gnu* | storm-chaos* | os2-emx* | rtmk-nova*) + os=-$maybe_os + basic_machine=`echo $1 | sed 's/^\(.*\)-\([^-]*-[^-]*\)$/\1/'` + ;; + *) + basic_machine=`echo $1 | sed 's/-[^-]*$//'` + if [ $basic_machine != $1 ] + then os=`echo $1 | sed 's/.*-/-/'` + else os=; fi + ;; +esac + +### Let's recognize common machines as not being operating systems so +### that things like config.sub decstation-3100 work. We also +### recognize some manufacturers as not being operating systems, so we +### can provide default operating systems below. +case $os in + -sun*os*) + # Prevent following clause from handling this invalid input. + ;; + -dec* | -mips* | -sequent* | -encore* | -pc532* | -sgi* | -sony* | \ + -att* | -7300* | -3300* | -delta* | -motorola* | -sun[234]* | \ + -unicom* | -ibm* | -next | -hp | -isi* | -apollo | -altos* | \ + -convergent* | -ncr* | -news | -32* | -3600* | -3100* | -hitachi* |\ + -c[123]* | -convex* | -sun | -crds | -omron* | -dg | -ultra | -tti* | \ + -harris | -dolphin | -highlevel | -gould | -cbm | -ns | -masscomp | \ + -apple | -axis | -knuth | -cray) + os= + basic_machine=$1 + ;; + -sim | -cisco | -oki | -wec | -winbond) + os= + basic_machine=$1 + ;; + -scout) + ;; + -wrs) + os=-vxworks + basic_machine=$1 + ;; + -chorusos*) + os=-chorusos + basic_machine=$1 + ;; + -chorusrdb) + os=-chorusrdb + basic_machine=$1 + ;; + -hiux*) + os=-hiuxwe2 + ;; + -sco5) + os=-sco3.2v5 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco4) + os=-sco3.2v4 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco3.2.[4-9]*) + os=`echo $os | sed -e 's/sco3.2./sco3.2v/'` + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco3.2v[4-9]*) + # Don't forget version if it is 3.2v4 or newer. + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -sco*) + os=-sco3.2v2 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -udk*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -isc) + os=-isc2.2 + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -clix*) + basic_machine=clipper-intergraph + ;; + -isc*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-pc/'` + ;; + -lynx*) + os=-lynxos + ;; + -ptx*) + basic_machine=`echo $1 | sed -e 's/86-.*/86-sequent/'` + ;; + -windowsnt*) + os=`echo $os | sed -e 's/windowsnt/winnt/'` + ;; + -psos*) + os=-psos + ;; + -mint | -mint[0-9]*) + basic_machine=m68k-atari + os=-mint + ;; +esac + +# Decode aliases for certain CPU-COMPANY combinations. +case $basic_machine in + # Recognize the basic CPU types without company name. + # Some are omitted here because they have special meanings below. + 1750a | 580 \ + | a29k \ + | alpha | alphaev[4-8] | alphaev56 | alphaev6[78] | alphapca5[67] \ + | alpha64 | alpha64ev[4-8] | alpha64ev56 | alpha64ev6[78] | alpha64pca5[67] \ + | am33_2.0 \ + | arc | arm | arm[bl]e | arme[lb] | armv[2345] | armv[345][lb] | avr \ + | c4x | clipper \ + | d10v | d30v | dlx | dsp16xx \ + | fr30 | frv \ + | h8300 | h8500 | hppa | hppa1.[01] | hppa2.0 | hppa2.0[nw] | hppa64 \ + | i370 | i860 | i960 | ia64 \ + | ip2k | iq2000 \ + | m32r | m32rle | m68000 | m68k | m88k | mcore \ + | mips | mipsbe | mipseb | mipsel | mipsle \ + | mips16 \ + | mips64 | mips64el \ + | mips64vr | mips64vrel \ + | mips64orion | mips64orionel \ + | mips64vr4100 | mips64vr4100el \ + | mips64vr4300 | mips64vr4300el \ + | mips64vr5000 | mips64vr5000el \ + | mipsisa32 | mipsisa32el \ + | mipsisa32r2 | mipsisa32r2el \ + | mipsisa64 | mipsisa64el \ + | mipsisa64r2 | mipsisa64r2el \ + | mipsisa64sb1 | mipsisa64sb1el \ + | mipsisa64sr71k | mipsisa64sr71kel \ + | mipstx39 | mipstx39el \ + | mn10200 | mn10300 \ + | msp430 \ + | ns16k | ns32k \ + | openrisc | or32 \ + | pdp10 | pdp11 | pj | pjl \ + | powerpc | powerpc64 | powerpc64le | powerpcle | ppcbe \ + | pyramid \ + | sh | sh[1234] | sh[23]e | sh[34]eb | shbe | shle | sh[1234]le | sh3ele \ + | sh64 | sh64le \ + | sparc | sparc64 | sparc86x | sparclet | sparclite | sparcv8 | sparcv9 | sparcv9b \ + | strongarm \ + | tahoe | thumb | tic4x | tic80 | tron \ + | v850 | v850e \ + | we32k \ + | x86 | xscale | xstormy16 | xtensa \ + | z8k) + basic_machine=$basic_machine-unknown + ;; + m6811 | m68hc11 | m6812 | m68hc12) + # Motorola 68HC11/12. + basic_machine=$basic_machine-unknown + os=-none + ;; + m88110 | m680[12346]0 | m683?2 | m68360 | m5200 | v70 | w65 | z8k) + ;; + + # We use `pc' rather than `unknown' + # because (1) that's what they normally are, and + # (2) the word "unknown" tends to confuse beginning users. + i*86 | x86_64) + basic_machine=$basic_machine-pc + ;; + # Object if more than one company name word. + *-*-*) + echo Invalid configuration \`$1\': machine \`$basic_machine\' not recognized 1>&2 + exit 1 + ;; + # Recognize the basic CPU types with company name. + 580-* \ + | a29k-* \ + | alpha-* | alphaev[4-8]-* | alphaev56-* | alphaev6[78]-* \ + | alpha64-* | alpha64ev[4-8]-* | alpha64ev56-* | alpha64ev6[78]-* \ + | alphapca5[67]-* | alpha64pca5[67]-* | arc-* \ + | arm-* | armbe-* | armle-* | armeb-* | armv*-* \ + | avr-* \ + | bs2000-* \ + | c[123]* | c30-* | [cjt]90-* | c4x-* | c54x-* | c55x-* | c6x-* \ + | clipper-* | craynv-* | cydra-* \ + | d10v-* | d30v-* | dlx-* \ + | elxsi-* \ + | f30[01]-* | f700-* | fr30-* | frv-* | fx80-* \ + | h8300-* | h8500-* \ + | hppa-* | hppa1.[01]-* | hppa2.0-* | hppa2.0[nw]-* | hppa64-* \ + | i*86-* | i860-* | i960-* | ia64-* \ + | ip2k-* | iq2000-* \ + | m32r-* | m32rle-* \ + | m68000-* | m680[012346]0-* | m68360-* | m683?2-* | m68k-* \ + | m88110-* | m88k-* | mcore-* \ + | mips-* | mipsbe-* | mipseb-* | mipsel-* | mipsle-* \ + | mips16-* \ + | mips64-* | mips64el-* \ + | mips64vr-* | mips64vrel-* \ + | mips64orion-* | mips64orionel-* \ + | mips64vr4100-* | mips64vr4100el-* \ + | mips64vr4300-* | mips64vr4300el-* \ + | mips64vr5000-* | mips64vr5000el-* \ + | mipsisa32-* | mipsisa32el-* \ + | mipsisa32r2-* | mipsisa32r2el-* \ + | mipsisa64-* | mipsisa64el-* \ + | mipsisa64r2-* | mipsisa64r2el-* \ + | mipsisa64sb1-* | mipsisa64sb1el-* \ + | mipsisa64sr71k-* | mipsisa64sr71kel-* \ + | mipstx39-* | mipstx39el-* \ + | mmix-* \ + | msp430-* \ + | none-* | np1-* | ns16k-* | ns32k-* \ + | orion-* \ + | pdp10-* | pdp11-* | pj-* | pjl-* | pn-* | power-* \ + | powerpc-* | powerpc64-* | powerpc64le-* | powerpcle-* | ppcbe-* \ + | pyramid-* \ + | romp-* | rs6000-* \ + | sh-* | sh[1234]-* | sh[23]e-* | sh[34]eb-* | shbe-* \ + | shle-* | sh[1234]le-* | sh3ele-* | sh64-* | sh64le-* \ + | sparc-* | sparc64-* | sparc86x-* | sparclet-* | sparclite-* \ + | sparcv8-* | sparcv9-* | sparcv9b-* | strongarm-* | sv1-* | sx?-* \ + | tahoe-* | thumb-* \ + | tic30-* | tic4x-* | tic54x-* | tic55x-* | tic6x-* | tic80-* \ + | tron-* \ + | v850-* | v850e-* | vax-* \ + | we32k-* \ + | x86-* | x86_64-* | xps100-* | xscale-* | xstormy16-* \ + | xtensa-* \ + | ymp-* \ + | z8k-*) + ;; + # Recognize the various machine names and aliases which stand + # for a CPU type and a company and sometimes even an OS. + 386bsd) + basic_machine=i386-unknown + os=-bsd + ;; + 3b1 | 7300 | 7300-att | att-7300 | pc7300 | safari | unixpc) + basic_machine=m68000-att + ;; + 3b*) + basic_machine=we32k-att + ;; + a29khif) + basic_machine=a29k-amd + os=-udi + ;; + abacus) + basic_machine=abacus-unknown + ;; + adobe68k) + basic_machine=m68010-adobe + os=-scout + ;; + alliant | fx80) + basic_machine=fx80-alliant + ;; + altos | altos3068) + basic_machine=m68k-altos + ;; + am29k) + basic_machine=a29k-none + os=-bsd + ;; + amd64) + basic_machine=x86_64-pc + ;; + amd64-*) + basic_machine=x86_64-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + amdahl) + basic_machine=580-amdahl + os=-sysv + ;; + amiga | amiga-*) + basic_machine=m68k-unknown + ;; + amigaos | amigados) + basic_machine=m68k-unknown + os=-amigaos + ;; + amigaunix | amix) + basic_machine=m68k-unknown + os=-sysv4 + ;; + apollo68) + basic_machine=m68k-apollo + os=-sysv + ;; + apollo68bsd) + basic_machine=m68k-apollo + os=-bsd + ;; + aux) + basic_machine=m68k-apple + os=-aux + ;; + balance) + basic_machine=ns32k-sequent + os=-dynix + ;; + c90) + basic_machine=c90-cray + os=-unicos + ;; + convex-c1) + basic_machine=c1-convex + os=-bsd + ;; + convex-c2) + basic_machine=c2-convex + os=-bsd + ;; + convex-c32) + basic_machine=c32-convex + os=-bsd + ;; + convex-c34) + basic_machine=c34-convex + os=-bsd + ;; + convex-c38) + basic_machine=c38-convex + os=-bsd + ;; + cray | j90) + basic_machine=j90-cray + os=-unicos + ;; + craynv) + basic_machine=craynv-cray + os=-unicosmp + ;; + cr16c) + basic_machine=cr16c-unknown + os=-elf + ;; + crds | unos) + basic_machine=m68k-crds + ;; + cris | cris-* | etrax*) + basic_machine=cris-axis + ;; + crx) + basic_machine=crx-unknown + os=-elf + ;; + da30 | da30-*) + basic_machine=m68k-da30 + ;; + decstation | decstation-3100 | pmax | pmax-* | pmin | dec3100 | decstatn) + basic_machine=mips-dec + ;; + decsystem10* | dec10*) + basic_machine=pdp10-dec + os=-tops10 + ;; + decsystem20* | dec20*) + basic_machine=pdp10-dec + os=-tops20 + ;; + delta | 3300 | motorola-3300 | motorola-delta \ + | 3300-motorola | delta-motorola) + basic_machine=m68k-motorola + ;; + delta88) + basic_machine=m88k-motorola + os=-sysv3 + ;; + dpx20 | dpx20-*) + basic_machine=rs6000-bull + os=-bosx + ;; + dpx2* | dpx2*-bull) + basic_machine=m68k-bull + os=-sysv3 + ;; + ebmon29k) + basic_machine=a29k-amd + os=-ebmon + ;; + elxsi) + basic_machine=elxsi-elxsi + os=-bsd + ;; + encore | umax | mmax) + basic_machine=ns32k-encore + ;; + es1800 | OSE68k | ose68k | ose | OSE) + basic_machine=m68k-ericsson + os=-ose + ;; + fx2800) + basic_machine=i860-alliant + ;; + genix) + basic_machine=ns32k-ns + ;; + gmicro) + basic_machine=tron-gmicro + os=-sysv + ;; + go32) + basic_machine=i386-pc + os=-go32 + ;; + h3050r* | hiux*) + basic_machine=hppa1.1-hitachi + os=-hiuxwe2 + ;; + h8300hms) + basic_machine=h8300-hitachi + os=-hms + ;; + h8300xray) + basic_machine=h8300-hitachi + os=-xray + ;; + h8500hms) + basic_machine=h8500-hitachi + os=-hms + ;; + harris) + basic_machine=m88k-harris + os=-sysv3 + ;; + hp300-*) + basic_machine=m68k-hp + ;; + hp300bsd) + basic_machine=m68k-hp + os=-bsd + ;; + hp300hpux) + basic_machine=m68k-hp + os=-hpux + ;; + hp3k9[0-9][0-9] | hp9[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hp9k2[0-9][0-9] | hp9k31[0-9]) + basic_machine=m68000-hp + ;; + hp9k3[2-9][0-9]) + basic_machine=m68k-hp + ;; + hp9k6[0-9][0-9] | hp6[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hp9k7[0-79][0-9] | hp7[0-79][0-9]) + basic_machine=hppa1.1-hp + ;; + hp9k78[0-9] | hp78[0-9]) + # FIXME: really hppa2.0-hp + basic_machine=hppa1.1-hp + ;; + hp9k8[67]1 | hp8[67]1 | hp9k80[24] | hp80[24] | hp9k8[78]9 | hp8[78]9 | hp9k893 | hp893) + # FIXME: really hppa2.0-hp + basic_machine=hppa1.1-hp + ;; + hp9k8[0-9][13679] | hp8[0-9][13679]) + basic_machine=hppa1.1-hp + ;; + hp9k8[0-9][0-9] | hp8[0-9][0-9]) + basic_machine=hppa1.0-hp + ;; + hppa-next) + os=-nextstep3 + ;; + hppaosf) + basic_machine=hppa1.1-hp + os=-osf + ;; + hppro) + basic_machine=hppa1.1-hp + os=-proelf + ;; + i370-ibm* | ibm*) + basic_machine=i370-ibm + ;; +# I'm not sure what "Sysv32" means. Should this be sysv3.2? + i*86v32) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv32 + ;; + i*86v4*) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv4 + ;; + i*86v) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-sysv + ;; + i*86sol2) + basic_machine=`echo $1 | sed -e 's/86.*/86-pc/'` + os=-solaris2 + ;; + i386mach) + basic_machine=i386-mach + os=-mach + ;; + i386-vsta | vsta) + basic_machine=i386-unknown + os=-vsta + ;; + iris | iris4d) + basic_machine=mips-sgi + case $os in + -irix*) + ;; + *) + os=-irix4 + ;; + esac + ;; + isi68 | isi) + basic_machine=m68k-isi + os=-sysv + ;; + m88k-omron*) + basic_machine=m88k-omron + ;; + magnum | m3230) + basic_machine=mips-mips + os=-sysv + ;; + merlin) + basic_machine=ns32k-utek + os=-sysv + ;; + mingw32) + basic_machine=i386-pc + os=-mingw32 + ;; + miniframe) + basic_machine=m68000-convergent + ;; + *mint | -mint[0-9]* | *MiNT | *MiNT[0-9]*) + basic_machine=m68k-atari + os=-mint + ;; + mips3*-*) + basic_machine=`echo $basic_machine | sed -e 's/mips3/mips64/'` + ;; + mips3*) + basic_machine=`echo $basic_machine | sed -e 's/mips3/mips64/'`-unknown + ;; + monitor) + basic_machine=m68k-rom68k + os=-coff + ;; + morphos) + basic_machine=powerpc-unknown + os=-morphos + ;; + msdos) + basic_machine=i386-pc + os=-msdos + ;; + mvs) + basic_machine=i370-ibm + os=-mvs + ;; + ncr3000) + basic_machine=i486-ncr + os=-sysv4 + ;; + netbsd386) + basic_machine=i386-unknown + os=-netbsd + ;; + netwinder) + basic_machine=armv4l-rebel + os=-linux + ;; + news | news700 | news800 | news900) + basic_machine=m68k-sony + os=-newsos + ;; + news1000) + basic_machine=m68030-sony + os=-newsos + ;; + news-3600 | risc-news) + basic_machine=mips-sony + os=-newsos + ;; + necv70) + basic_machine=v70-nec + os=-sysv + ;; + next | m*-next ) + basic_machine=m68k-next + case $os in + -nextstep* ) + ;; + -ns2*) + os=-nextstep2 + ;; + *) + os=-nextstep3 + ;; + esac + ;; + nh3000) + basic_machine=m68k-harris + os=-cxux + ;; + nh[45]000) + basic_machine=m88k-harris + os=-cxux + ;; + nindy960) + basic_machine=i960-intel + os=-nindy + ;; + mon960) + basic_machine=i960-intel + os=-mon960 + ;; + nonstopux) + basic_machine=mips-compaq + os=-nonstopux + ;; + np1) + basic_machine=np1-gould + ;; + nsr-tandem) + basic_machine=nsr-tandem + ;; + op50n-* | op60c-*) + basic_machine=hppa1.1-oki + os=-proelf + ;; + or32 | or32-*) + basic_machine=or32-unknown + os=-coff + ;; + os400) + basic_machine=powerpc-ibm + os=-os400 + ;; + OSE68000 | ose68000) + basic_machine=m68000-ericsson + os=-ose + ;; + os68k) + basic_machine=m68k-none + os=-os68k + ;; + pa-hitachi) + basic_machine=hppa1.1-hitachi + os=-hiuxwe2 + ;; + paragon) + basic_machine=i860-intel + os=-osf + ;; + pbd) + basic_machine=sparc-tti + ;; + pbb) + basic_machine=m68k-tti + ;; + pc532 | pc532-*) + basic_machine=ns32k-pc532 + ;; + pentium | p5 | k5 | k6 | nexgen | viac3) + basic_machine=i586-pc + ;; + pentiumpro | p6 | 6x86 | athlon | athlon_*) + basic_machine=i686-pc + ;; + pentiumii | pentium2 | pentiumiii | pentium3) + basic_machine=i686-pc + ;; + pentium4) + basic_machine=i786-pc + ;; + pentium-* | p5-* | k5-* | k6-* | nexgen-* | viac3-*) + basic_machine=i586-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentiumpro-* | p6-* | 6x86-* | athlon-*) + basic_machine=i686-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentiumii-* | pentium2-* | pentiumiii-* | pentium3-*) + basic_machine=i686-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pentium4-*) + basic_machine=i786-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + pn) + basic_machine=pn-gould + ;; + power) basic_machine=power-ibm + ;; + ppc) basic_machine=powerpc-unknown + ;; + ppc-*) basic_machine=powerpc-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppcle | powerpclittle | ppc-le | powerpc-little) + basic_machine=powerpcle-unknown + ;; + ppcle-* | powerpclittle-*) + basic_machine=powerpcle-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppc64) basic_machine=powerpc64-unknown + ;; + ppc64-*) basic_machine=powerpc64-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ppc64le | powerpc64little | ppc64-le | powerpc64-little) + basic_machine=powerpc64le-unknown + ;; + ppc64le-* | powerpc64little-*) + basic_machine=powerpc64le-`echo $basic_machine | sed 's/^[^-]*-//'` + ;; + ps2) + basic_machine=i386-ibm + ;; + pw32) + basic_machine=i586-unknown + os=-pw32 + ;; + rom68k) + basic_machine=m68k-rom68k + os=-coff + ;; + rm[46]00) + basic_machine=mips-siemens + ;; + rtpc | rtpc-*) + basic_machine=romp-ibm + ;; + s390 | s390-*) + basic_machine=s390-ibm + ;; + s390x | s390x-*) + basic_machine=s390x-ibm + ;; + sa29200) + basic_machine=a29k-amd + os=-udi + ;; + sb1) + basic_machine=mipsisa64sb1-unknown + ;; + sb1el) + basic_machine=mipsisa64sb1el-unknown + ;; + sei) + basic_machine=mips-sei + os=-seiux + ;; + sequent) + basic_machine=i386-sequent + ;; + sh) + basic_machine=sh-hitachi + os=-hms + ;; + sh64) + basic_machine=sh64-unknown + ;; + sparclite-wrs | simso-wrs) + basic_machine=sparclite-wrs + os=-vxworks + ;; + sps7) + basic_machine=m68k-bull + os=-sysv2 + ;; + spur) + basic_machine=spur-unknown + ;; + st2000) + basic_machine=m68k-tandem + ;; + stratus) + basic_machine=i860-stratus + os=-sysv4 + ;; + sun2) + basic_machine=m68000-sun + ;; + sun2os3) + basic_machine=m68000-sun + os=-sunos3 + ;; + sun2os4) + basic_machine=m68000-sun + os=-sunos4 + ;; + sun3os3) + basic_machine=m68k-sun + os=-sunos3 + ;; + sun3os4) + basic_machine=m68k-sun + os=-sunos4 + ;; + sun4os3) + basic_machine=sparc-sun + os=-sunos3 + ;; + sun4os4) + basic_machine=sparc-sun + os=-sunos4 + ;; + sun4sol2) + basic_machine=sparc-sun + os=-solaris2 + ;; + sun3 | sun3-*) + basic_machine=m68k-sun + ;; + sun4) + basic_machine=sparc-sun + ;; + sun386 | sun386i | roadrunner) + basic_machine=i386-sun + ;; + sv1) + basic_machine=sv1-cray + os=-unicos + ;; + symmetry) + basic_machine=i386-sequent + os=-dynix + ;; + t3e) + basic_machine=alphaev5-cray + os=-unicos + ;; + t90) + basic_machine=t90-cray + os=-unicos + ;; + tic54x | c54x*) + basic_machine=tic54x-unknown + os=-coff + ;; + tic55x | c55x*) + basic_machine=tic55x-unknown + os=-coff + ;; + tic6x | c6x*) + basic_machine=tic6x-unknown + os=-coff + ;; + tx39) + basic_machine=mipstx39-unknown + ;; + tx39el) + basic_machine=mipstx39el-unknown + ;; + toad1) + basic_machine=pdp10-xkl + os=-tops20 + ;; + tower | tower-32) + basic_machine=m68k-ncr + ;; + tpf) + basic_machine=s390x-ibm + os=-tpf + ;; + udi29k) + basic_machine=a29k-amd + os=-udi + ;; + ultra3) + basic_machine=a29k-nyu + os=-sym1 + ;; + v810 | necv810) + basic_machine=v810-nec + os=-none + ;; + vaxv) + basic_machine=vax-dec + os=-sysv + ;; + vms) + basic_machine=vax-dec + os=-vms + ;; + vpp*|vx|vx-*) + basic_machine=f301-fujitsu + ;; + vxworks960) + basic_machine=i960-wrs + os=-vxworks + ;; + vxworks68) + basic_machine=m68k-wrs + os=-vxworks + ;; + vxworks29k) + basic_machine=a29k-wrs + os=-vxworks + ;; + w65*) + basic_machine=w65-wdc + os=-none + ;; + w89k-*) + basic_machine=hppa1.1-winbond + os=-proelf + ;; + xps | xps100) + basic_machine=xps100-honeywell + ;; + ymp) + basic_machine=ymp-cray + os=-unicos + ;; + z8k-*-coff) + basic_machine=z8k-unknown + os=-sim + ;; + none) + basic_machine=none-none + os=-none + ;; + +# Here we handle the default manufacturer of certain CPU types. It is in +# some cases the only manufacturer, in others, it is the most popular. + w89k) + basic_machine=hppa1.1-winbond + ;; + op50n) + basic_machine=hppa1.1-oki + ;; + op60c) + basic_machine=hppa1.1-oki + ;; + romp) + basic_machine=romp-ibm + ;; + mmix) + basic_machine=mmix-knuth + ;; + rs6000) + basic_machine=rs6000-ibm + ;; + vax) + basic_machine=vax-dec + ;; + pdp10) + # there are many clones, so DEC is not a safe bet + basic_machine=pdp10-unknown + ;; + pdp11) + basic_machine=pdp11-dec + ;; + we32k) + basic_machine=we32k-att + ;; + sh3 | sh4 | sh[34]eb | sh[1234]le | sh[23]ele) + basic_machine=sh-unknown + ;; + sh64) + basic_machine=sh64-unknown + ;; + sparc | sparcv8 | sparcv9 | sparcv9b) + basic_machine=sparc-sun + ;; + cydra) + basic_machine=cydra-cydrome + ;; + orion) + basic_machine=orion-highlevel + ;; + orion105) + basic_machine=clipper-highlevel + ;; + mac | mpw | mac-mpw) + basic_machine=m68k-apple + ;; + pmac | pmac-mpw) + basic_machine=powerpc-apple + ;; + *-unknown) + # Make sure to match an already-canonicalized machine name. + ;; + *) + echo Invalid configuration \`$1\': machine \`$basic_machine\' not recognized 1>&2 + exit 1 + ;; +esac + +# Here we canonicalize certain aliases for manufacturers. +case $basic_machine in + *-digital*) + basic_machine=`echo $basic_machine | sed 's/digital.*/dec/'` + ;; + *-commodore*) + basic_machine=`echo $basic_machine | sed 's/commodore.*/cbm/'` + ;; + *) + ;; +esac + +# Decode manufacturer-specific aliases for certain operating systems. + +if [ x"$os" != x"" ] +then +case $os in + # First match some system type aliases + # that might get confused with valid system types. + # -solaris* is a basic system type, with this one exception. + -solaris1 | -solaris1.*) + os=`echo $os | sed -e 's|solaris1|sunos4|'` + ;; + -solaris) + os=-solaris2 + ;; + -svr4*) + os=-sysv4 + ;; + -unixware*) + os=-sysv4.2uw + ;; + -gnu/linux*) + os=`echo $os | sed -e 's|gnu/linux|linux-gnu|'` + ;; + # First accept the basic system types. + # The portable systems comes first. + # Each alternative MUST END IN A *, to match a version number. + # -sysv* is not here because it comes later, after sysvr4. + -gnu* | -bsd* | -mach* | -minix* | -genix* | -ultrix* | -irix* \ + | -*vms* | -sco* | -esix* | -isc* | -aix* | -sunos | -sunos[34]*\ + | -hpux* | -unos* | -osf* | -luna* | -dgux* | -solaris* | -sym* \ + | -amigaos* | -amigados* | -msdos* | -newsos* | -unicos* | -aof* \ + | -aos* \ + | -nindy* | -vxsim* | -vxworks* | -ebmon* | -hms* | -mvs* \ + | -clix* | -riscos* | -uniplus* | -iris* | -rtu* | -xenix* \ + | -hiux* | -386bsd* | -knetbsd* | -mirbsd* | -netbsd* | -openbsd* \ + | -ekkobsd* | -kfreebsd* | -freebsd* | -riscix* | -lynxos* \ + | -bosx* | -nextstep* | -cxux* | -aout* | -elf* | -oabi* \ + | -ptx* | -coff* | -ecoff* | -winnt* | -domain* | -vsta* \ + | -udi* | -eabi* | -lites* | -ieee* | -go32* | -aux* \ + | -chorusos* | -chorusrdb* \ + | -cygwin* | -pe* | -psos* | -moss* | -proelf* | -rtems* \ + | -mingw32* | -linux-gnu* | -linux-uclibc* | -uxpv* | -beos* | -mpeix* | -udk* \ + | -interix* | -uwin* | -mks* | -rhapsody* | -darwin* | -opened* \ + | -openstep* | -oskit* | -conix* | -pw32* | -nonstopux* \ + | -storm-chaos* | -tops10* | -tenex* | -tops20* | -its* \ + | -os2* | -vos* | -palmos* | -uclinux* | -nucleus* \ + | -morphos* | -superux* | -rtmk* | -rtmk-nova* | -windiss* \ + | -powermax* | -dnix* | -nx6 | -nx7 | -sei* | -dragonfly*) + # Remember, each alternative MUST END IN *, to match a version number. + ;; + -qnx*) + case $basic_machine in + x86-* | i*86-*) + ;; + *) + os=-nto$os + ;; + esac + ;; + -nto-qnx*) + ;; + -nto*) + os=`echo $os | sed -e 's|nto|nto-qnx|'` + ;; + -sim | -es1800* | -hms* | -xray | -os68k* | -none* | -v88r* \ + | -windows* | -osx | -abug | -netware* | -os9* | -beos* \ + | -macos* | -mpw* | -magic* | -mmixware* | -mon960* | -lnews*) + ;; + -mac*) + os=`echo $os | sed -e 's|mac|macos|'` + ;; + -linux-dietlibc) + os=-linux-dietlibc + ;; + -linux*) + os=`echo $os | sed -e 's|linux|linux-gnu|'` + ;; + -sunos5*) + os=`echo $os | sed -e 's|sunos5|solaris2|'` + ;; + -sunos6*) + os=`echo $os | sed -e 's|sunos6|solaris3|'` + ;; + -opened*) + os=-openedition + ;; + -os400*) + os=-os400 + ;; + -wince*) + os=-wince + ;; + -osfrose*) + os=-osfrose + ;; + -osf*) + os=-osf + ;; + -utek*) + os=-bsd + ;; + -dynix*) + os=-bsd + ;; + -acis*) + os=-aos + ;; + -atheos*) + os=-atheos + ;; + -syllable*) + os=-syllable + ;; + -386bsd) + os=-bsd + ;; + -ctix* | -uts*) + os=-sysv + ;; + -nova*) + os=-rtmk-nova + ;; + -ns2 ) + os=-nextstep2 + ;; + -nsk*) + os=-nsk + ;; + # Preserve the version number of sinix5. + -sinix5.*) + os=`echo $os | sed -e 's|sinix|sysv|'` + ;; + -sinix*) + os=-sysv4 + ;; + -tpf*) + os=-tpf + ;; + -triton*) + os=-sysv3 + ;; + -oss*) + os=-sysv3 + ;; + -svr4) + os=-sysv4 + ;; + -svr3) + os=-sysv3 + ;; + -sysvr4) + os=-sysv4 + ;; + # This must come after -sysvr4. + -sysv*) + ;; + -ose*) + os=-ose + ;; + -es1800*) + os=-ose + ;; + -xenix) + os=-xenix + ;; + -*mint | -mint[0-9]* | -*MiNT | -MiNT[0-9]*) + os=-mint + ;; + -aros*) + os=-aros + ;; + -kaos*) + os=-kaos + ;; + -none) + ;; + *) + # Get rid of the `-' at the beginning of $os. + os=`echo $os | sed 's/[^-]*-//'` + echo Invalid configuration \`$1\': system \`$os\' not recognized 1>&2 + exit 1 + ;; +esac +else + +# Here we handle the default operating systems that come with various machines. +# The value should be what the vendor currently ships out the door with their +# machine or put another way, the most popular os provided with the machine. + +# Note that if you're going to try to match "-MANUFACTURER" here (say, +# "-sun"), then you have to tell the case statement up towards the top +# that MANUFACTURER isn't an operating system. Otherwise, code above +# will signal an error saying that MANUFACTURER isn't an operating +# system, and we'll never get to this point. + +case $basic_machine in + *-acorn) + os=-riscix1.2 + ;; + arm*-rebel) + os=-linux + ;; + arm*-semi) + os=-aout + ;; + c4x-* | tic4x-*) + os=-coff + ;; + # This must come before the *-dec entry. + pdp10-*) + os=-tops20 + ;; + pdp11-*) + os=-none + ;; + *-dec | vax-*) + os=-ultrix4.2 + ;; + m68*-apollo) + os=-domain + ;; + i386-sun) + os=-sunos4.0.2 + ;; + m68000-sun) + os=-sunos3 + # This also exists in the configure program, but was not the + # default. + # os=-sunos4 + ;; + m68*-cisco) + os=-aout + ;; + mips*-cisco) + os=-elf + ;; + mips*-*) + os=-elf + ;; + or32-*) + os=-coff + ;; + *-tti) # must be before sparc entry or we get the wrong os. + os=-sysv3 + ;; + sparc-* | *-sun) + os=-sunos4.1.1 + ;; + *-be) + os=-beos + ;; + *-ibm) + os=-aix + ;; + *-knuth) + os=-mmixware + ;; + *-wec) + os=-proelf + ;; + *-winbond) + os=-proelf + ;; + *-oki) + os=-proelf + ;; + *-hp) + os=-hpux + ;; + *-hitachi) + os=-hiux + ;; + i860-* | *-att | *-ncr | *-altos | *-motorola | *-convergent) + os=-sysv + ;; + *-cbm) + os=-amigaos + ;; + *-dg) + os=-dgux + ;; + *-dolphin) + os=-sysv3 + ;; + m68k-ccur) + os=-rtu + ;; + m88k-omron*) + os=-luna + ;; + *-next ) + os=-nextstep + ;; + *-sequent) + os=-ptx + ;; + *-crds) + os=-unos + ;; + *-ns) + os=-genix + ;; + i370-*) + os=-mvs + ;; + *-next) + os=-nextstep3 + ;; + *-gould) + os=-sysv + ;; + *-highlevel) + os=-bsd + ;; + *-encore) + os=-bsd + ;; + *-sgi) + os=-irix + ;; + *-siemens) + os=-sysv4 + ;; + *-masscomp) + os=-rtu + ;; + f30[01]-fujitsu | f700-fujitsu) + os=-uxpv + ;; + *-rom68k) + os=-coff + ;; + *-*bug) + os=-coff + ;; + *-apple) + os=-macos + ;; + *-atari*) + os=-mint + ;; + *) + os=-none + ;; +esac +fi + +# Here we handle the case where we know the os, and the CPU type, but not the +# manufacturer. We pick the logical manufacturer. +vendor=unknown +case $basic_machine in + *-unknown) + case $os in + -riscix*) + vendor=acorn + ;; + -sunos*) + vendor=sun + ;; + -aix*) + vendor=ibm + ;; + -beos*) + vendor=be + ;; + -hpux*) + vendor=hp + ;; + -mpeix*) + vendor=hp + ;; + -hiux*) + vendor=hitachi + ;; + -unos*) + vendor=crds + ;; + -dgux*) + vendor=dg + ;; + -luna*) + vendor=omron + ;; + -genix*) + vendor=ns + ;; + -mvs* | -opened*) + vendor=ibm + ;; + -os400*) + vendor=ibm + ;; + -ptx*) + vendor=sequent + ;; + -tpf*) + vendor=ibm + ;; + -vxsim* | -vxworks* | -windiss*) + vendor=wrs + ;; + -aux*) + vendor=apple + ;; + -hms*) + vendor=hitachi + ;; + -mpw* | -macos*) + vendor=apple + ;; + -*mint | -mint[0-9]* | -*MiNT | -MiNT[0-9]*) + vendor=atari + ;; + -vos*) + vendor=stratus + ;; + esac + basic_machine=`echo $basic_machine | sed "s/unknown/$vendor/"` + ;; +esac + +echo $basic_machine$os +exit 0 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "timestamp='" +# time-stamp-format: "%:y-%02m-%02d" +# time-stamp-end: "'" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure new file mode 100755 index 00000000..dad8ae41 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure @@ -0,0 +1,5965 @@ +#! /bin/sh +# Guess values for system-dependent variables and create Makefiles. +# Generated by GNU Autoconf 2.59 for ViennaRNA 1.6. +# +# Report bugs to . +# +# Copyright (C) 2003 Free Software Foundation, Inc. +# This configure script is free software; the Free Software Foundation +# gives unlimited permission to copy, distribute and modify it. +## --------------------- ## +## M4sh Initialization. ## +## --------------------- ## + +# Be Bourne compatible +if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then + emulate sh + NULLCMD=: + # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which + # is contrary to our usage. Disable this feature. + alias -g '${1+"$@"}'='"$@"' +elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then + set -o posix +fi +DUALCASE=1; export DUALCASE # for MKS sh + +# Support unset when possible. +if ( (MAIL=60; unset MAIL) || exit) >/dev/null 2>&1; then + as_unset=unset +else + as_unset=false +fi + + +# Work around bugs in pre-3.0 UWIN ksh. +$as_unset ENV MAIL MAILPATH +PS1='$ ' +PS2='> ' +PS4='+ ' + +# NLS nuisances. +for as_var in \ + LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \ + LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \ + LC_TELEPHONE LC_TIME +do + if (set +x; test -z "`(eval $as_var=C; export $as_var) 2>&1`"); then + eval $as_var=C; export $as_var + else + $as_unset $as_var + fi +done + +# Required to use basename. +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then + as_basename=basename +else + as_basename=false +fi + + +# Name of the executable. +as_me=`$as_basename "$0" || +$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \ + X"$0" : 'X\(//\)$' \| \ + X"$0" : 'X\(/\)$' \| \ + . : '\(.\)' 2>/dev/null || +echo X/"$0" | + sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; } + /^X\/\(\/\/\)$/{ s//\1/; q; } + /^X\/\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + + +# PATH needs CR, and LINENO needs CR and PATH. +# Avoid depending upon Character Ranges. +as_cr_letters='abcdefghijklmnopqrstuvwxyz' +as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ' +as_cr_Letters=$as_cr_letters$as_cr_LETTERS +as_cr_digits='0123456789' +as_cr_alnum=$as_cr_Letters$as_cr_digits + +# The user is always right. +if test "${PATH_SEPARATOR+set}" != set; then + echo "#! /bin/sh" >conf$$.sh + echo "exit 0" >>conf$$.sh + chmod +x conf$$.sh + if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then + PATH_SEPARATOR=';' + else + PATH_SEPARATOR=: + fi + rm -f conf$$.sh +fi + + + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" || { + # Find who we are. Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2 + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. 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See below for descriptions of some of the useful variables. + +Defaults for the options are specified in brackets. + +Configuration: + -h, --help display this help and exit + --help=short display options specific to this package + --help=recursive display the short help of all the included packages + -V, --version display version information and exit + -q, --quiet, --silent do not print \`checking...' messages + --cache-file=FILE cache test results in FILE [disabled] + -C, --config-cache alias for \`--cache-file=config.cache' + -n, --no-create do not create output files + --srcdir=DIR find the sources in DIR [configure dir or \`..'] + +_ACEOF + + cat <<_ACEOF +Installation directories: + --prefix=PREFIX install architecture-independent files in PREFIX + [$ac_default_prefix] + --exec-prefix=EPREFIX install architecture-dependent files in EPREFIX + [PREFIX] + +By default, \`make install' will install all the files in +\`$ac_default_prefix/bin', \`$ac_default_prefix/lib' etc. You can specify +an installation prefix other than \`$ac_default_prefix' using \`--prefix', +for instance \`--prefix=\$HOME'. + +For better control, use the options below. + +Fine tuning of the installation directories: + --bindir=DIR user executables [EPREFIX/bin] + --sbindir=DIR system admin executables [EPREFIX/sbin] + --libexecdir=DIR program executables [EPREFIX/libexec] + --datadir=DIR read-only architecture-independent data [PREFIX/share] + --sysconfdir=DIR read-only single-machine data [PREFIX/etc] + --sharedstatedir=DIR modifiable architecture-independent data [PREFIX/com] + --localstatedir=DIR modifiable single-machine data [PREFIX/var] + --libdir=DIR object code libraries [EPREFIX/lib] + --includedir=DIR C header files [PREFIX/include] + --oldincludedir=DIR C header files for non-gcc [/usr/include] + --infodir=DIR info documentation [PREFIX/info] + --mandir=DIR man documentation [PREFIX/man] +_ACEOF + + cat <<\_ACEOF + +Program names: + --program-prefix=PREFIX prepend PREFIX to installed program names + --program-suffix=SUFFIX append SUFFIX to installed program names + --program-transform-name=PROGRAM run sed PROGRAM on installed program names + +System types: + --build=BUILD configure for building on BUILD [guessed] + --host=HOST cross-compile to build programs to run on HOST [BUILD] +_ACEOF +fi + +if test -n "$ac_init_help"; then + case $ac_init_help in + short | recursive ) echo "Configuration of ViennaRNA 1.6:";; + esac + cat <<\_ACEOF + +Optional Features: + --disable-FEATURE do not include FEATURE (same as --enable-FEATURE=no) + --enable-FEATURE[=ARG] include FEATURE [ARG=yes] + --enable-floatpf use float instead of double for partition function + --disable-dependency-tracking speeds up one-time build + --enable-dependency-tracking do not reject slow dependency extractors + +Optional Packages: + --with-PACKAGE[=ARG] use PACKAGE [ARG=yes] + --without-PACKAGE do not use PACKAGE (same as --with-PACKAGE=no) + --with-dmalloc use dmalloc, as in + http://www.dmalloc.com/dmalloc.tar.gz + --with-cluster build AnalyseSeqs and AnalyseDists + --without-perl don't build Perl module + --without-forester don't build RNAforester program + --without-kinfold don't build Kinfold program + +Some influential environment variables: + CC C compiler command + CFLAGS C compiler flags + LDFLAGS linker flags, e.g. -L if you have libraries in a + nonstandard directory + CPPFLAGS C/C++ preprocessor flags, e.g. -I if you have + headers in a nonstandard directory + CPP C preprocessor + +Use these variables to override the choices made by `configure' or to help +it to find libraries and programs with nonstandard names/locations. + +Report bugs to . +_ACEOF +fi + +if test "$ac_init_help" = "recursive"; then + # If there are subdirs, report their specific --help. + ac_popdir=`pwd` + for ac_dir in : $ac_subdirs_all; do test "x$ac_dir" = x: && continue + test -d $ac_dir || continue + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +echo "$as_me:$LINENO: checking whether build environment is sane" >&5 +echo $ECHO_N "checking whether build environment is sane... $ECHO_C" >&6 +# Just in case +sleep 1 +echo timestamp > conftest.file +# Do `set' in a subshell so we don't clobber the current shell's +# arguments. Must try -L first in case configure is actually a +# symlink; some systems play weird games with the mod time of symlinks +# (eg FreeBSD returns the mod time of the symlink's containing +# directory). +if ( + set X `ls -Lt $srcdir/configure conftest.file 2> /dev/null` + if test "$*" = "X"; then + # -L didn't work. + set X `ls -t $srcdir/configure conftest.file` + fi + rm -f conftest.file + if test "$*" != "X $srcdir/configure conftest.file" \ + && test "$*" != "X conftest.file $srcdir/configure"; then + + # If neither matched, then we have a broken ls. This can happen + # if, for instance, CONFIG_SHELL is bash and it inherits a + # broken ls alias from the environment. This has actually + # happened. Such a system could not be considered "sane". + { { echo "$as_me:$LINENO: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&5 +echo "$as_me: error: ls -t appears to fail. Make sure there is not a broken +alias in your environment" >&2;} + { (exit 1); exit 1; }; } + fi + + test "$2" = conftest.file + ) +then + # Ok. + : +else + { { echo "$as_me:$LINENO: error: newly created file is older than distributed files! +Check your system clock" >&5 +echo "$as_me: error: newly created file is older than distributed files! +Check your system clock" >&2;} + { (exit 1); exit 1; }; } +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 +test "$program_prefix" != NONE && + program_transform_name="s,^,$program_prefix,;$program_transform_name" +# Use a double $ so make ignores it. +test "$program_suffix" != NONE && + program_transform_name="s,\$,$program_suffix,;$program_transform_name" +# Double any \ or $. echo might interpret backslashes. +# By default was `s,x,x', remove it if useless. +cat <<\_ACEOF >conftest.sed +s/[\\$]/&&/g;s/;s,x,x,$// +_ACEOF +program_transform_name=`echo $program_transform_name | sed -f conftest.sed` +rm conftest.sed + +# expand $ac_aux_dir to an absolute path +am_aux_dir=`cd $ac_aux_dir && pwd` + +test x"${MISSING+set}" = xset || MISSING="\${SHELL} $am_aux_dir/missing" +# Use eval to expand $SHELL +if eval "$MISSING --run true"; then + am_missing_run="$MISSING --run " +else + am_missing_run= + { echo "$as_me:$LINENO: WARNING: \`missing' script is too old or missing" >&5 +echo "$as_me: WARNING: \`missing' script is too old or missing" >&2;} +fi + +if mkdir -p --version . >/dev/null 2>&1 && test ! -d ./--version; then + # We used to keeping the `.' as first argument, in order to + # allow $(mkdir_p) to be used without argument. As in + # $(mkdir_p) $(somedir) + # where $(somedir) is conditionally defined. However this is wrong + # for two reasons: + # 1. if the package is installed by a user who cannot write `.' + # make install will fail, + # 2. the above comment should most certainly read + # $(mkdir_p) $(DESTDIR)$(somedir) + # so it does not work when $(somedir) is undefined and + # $(DESTDIR) is not. + # To support the latter case, we have to write + # test -z "$(somedir)" || $(mkdir_p) $(DESTDIR)$(somedir), + # so the `.' trick is pointless. + mkdir_p='mkdir -p --' +else + # On NextStep and OpenStep, the `mkdir' command does not + # recognize any option. It will interpret all options as + # directories to create, and then abort because `.' already + # exists. + for d in ./-p ./--version; + do + test -d $d && rmdir $d + done + # $(mkinstalldirs) is defined by Automake if mkinstalldirs exists. + if test -f "$ac_aux_dir/mkinstalldirs"; then + mkdir_p='$(mkinstalldirs)' + else + mkdir_p='$(install_sh) -d' + fi +fi + +for ac_prog in gawk mawk nawk awk +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_AWK+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$AWK"; then + ac_cv_prog_AWK="$AWK" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_AWK="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +AWK=$ac_cv_prog_AWK +if test -n "$AWK"; then + echo "$as_me:$LINENO: result: $AWK" >&5 +echo "${ECHO_T}$AWK" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$AWK" && break +done + +echo "$as_me:$LINENO: checking whether ${MAKE-make} sets \$(MAKE)" >&5 +echo $ECHO_N "checking whether ${MAKE-make} sets \$(MAKE)... $ECHO_C" >&6 +set dummy ${MAKE-make}; ac_make=`echo "$2" | sed 'y,:./+-,___p_,'` +if eval "test \"\${ac_cv_prog_make_${ac_make}_set+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.make <<\_ACEOF +all: + @echo 'ac_maketemp="$(MAKE)"' +_ACEOF +# GNU make sometimes prints "make[1]: Entering...", which would confuse us. +eval `${MAKE-make} -f conftest.make 2>/dev/null | grep temp=` +if test -n "$ac_maketemp"; then + eval ac_cv_prog_make_${ac_make}_set=yes +else + eval ac_cv_prog_make_${ac_make}_set=no +fi +rm -f conftest.make +fi +if eval "test \"`echo '$ac_cv_prog_make_'${ac_make}_set`\" = yes"; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + SET_MAKE= +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 + SET_MAKE="MAKE=${MAKE-make}" +fi + +rm -rf .tst 2>/dev/null +mkdir .tst 2>/dev/null +if test -d .tst; then + am__leading_dot=. +else + am__leading_dot=_ +fi +rmdir .tst 2>/dev/null + +# test to see if srcdir already configured +if test "`cd $srcdir && pwd`" != "`pwd`" && + test -f $srcdir/config.status; then + { { echo "$as_me:$LINENO: error: source directory already configured; run \"make distclean\" there first" >&5 +echo "$as_me: error: source directory already configured; run \"make distclean\" there first" >&2;} + { (exit 1); exit 1; }; } +fi + +# test whether we have cygpath +if test -z "$CYGPATH_W"; then + if (cygpath --version) >/dev/null 2>/dev/null; then + CYGPATH_W='cygpath -w' + else + CYGPATH_W=echo + fi +fi + + +# Define the identity of the package. + PACKAGE='ViennaRNA' + VERSION='1.6' + + +cat >>confdefs.h <<_ACEOF +#define PACKAGE "$PACKAGE" +_ACEOF + + +cat >>confdefs.h <<_ACEOF +#define VERSION "$VERSION" +_ACEOF + +# Some tools Automake needs. + +ACLOCAL=${ACLOCAL-"${am_missing_run}aclocal-${am__api_version}"} + + +AUTOCONF=${AUTOCONF-"${am_missing_run}autoconf"} + + +AUTOMAKE=${AUTOMAKE-"${am_missing_run}automake-${am__api_version}"} + + +AUTOHEADER=${AUTOHEADER-"${am_missing_run}autoheader"} + + +MAKEINFO=${MAKEINFO-"${am_missing_run}makeinfo"} + +install_sh=${install_sh-"$am_aux_dir/install-sh"} + +# Installed binaries are usually stripped using `strip' when the user +# run `make install-strip'. However `strip' might not be the right +# tool to use in cross-compilation environments, therefore Automake +# will honor the `STRIP' environment variable to overrule this program. +if test "$cross_compiling" != no; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}strip", so it can be a program name with args. +set dummy ${ac_tool_prefix}strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$STRIP"; then + ac_cv_prog_STRIP="$STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_STRIP="${ac_tool_prefix}strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +STRIP=$ac_cv_prog_STRIP +if test -n "$STRIP"; then + echo "$as_me:$LINENO: result: $STRIP" >&5 +echo "${ECHO_T}$STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_STRIP"; then + ac_ct_STRIP=$STRIP + # Extract the first word of "strip", so it can be a program name with args. +set dummy strip; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_STRIP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_STRIP"; then + ac_cv_prog_ac_ct_STRIP="$ac_ct_STRIP" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_STRIP="strip" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_STRIP" && ac_cv_prog_ac_ct_STRIP=":" +fi +fi +ac_ct_STRIP=$ac_cv_prog_ac_ct_STRIP +if test -n "$ac_ct_STRIP"; then + echo "$as_me:$LINENO: result: $ac_ct_STRIP" >&5 +echo "${ECHO_T}$ac_ct_STRIP" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + STRIP=$ac_ct_STRIP +else + STRIP="$ac_cv_prog_STRIP" +fi + +fi +INSTALL_STRIP_PROGRAM="\${SHELL} \$(install_sh) -c -s" + +# We need awk for the "check" target. The system "awk" is bad on +# some platforms. +# Always define AMTAR for backward compatibility. + +AMTAR=${AMTAR-"${am_missing_run}tar"} + +am__tar='${AMTAR} chof - "$$tardir"'; am__untar='${AMTAR} xf -' + + + + + + +echo "$as_me:$LINENO: checking if malloc debugging is wanted" >&5 +echo $ECHO_N "checking if malloc debugging is wanted... $ECHO_C" >&6 + +# Check whether --with-dmalloc or --without-dmalloc was given. +if test "${with_dmalloc+set}" = set; then + withval="$with_dmalloc" + if test "$withval" = yes; then + echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +cat >>confdefs.h <<\_ACEOF +#define WITH_DMALLOC 1 +_ACEOF + + LIBS="$LIBS -ldmalloc" + LDFLAGS="$LDFLAGS -g" +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi; + + +# Check whether --with-cluster or --without-cluster was given. +if test "${with_cluster+set}" = set; then + withval="$with_cluster" + +fi; + +# Check whether --with-perl or --without-perl was given. +if test "${with_perl+set}" = set; then + withval="$with_perl" + +fi; + +# Check whether --with-forester or --without-forester was given. +if test "${with_forester+set}" = set; then + withval="$with_forester" + +fi; + +# Check whether --with-kinfold or --without-kinfold was given. +if test "${with_kinfold+set}" = set; then + withval="$with_kinfold" + +fi; +# Check whether --enable-floatpf or --disable-floatpf was given. +if test "${enable_floatpf+set}" = set; then + enableval="$enable_floatpf" + +fi; + + ac_config_headers="$ac_config_headers config.h" + + + + +ISODATE=`date +%Y-%m-%d` + + +# Make sure we can run config.sub. +$ac_config_sub sun4 >/dev/null 2>&1 || + { { echo "$as_me:$LINENO: error: cannot run $ac_config_sub" >&5 +echo "$as_me: error: cannot run $ac_config_sub" >&2;} + { (exit 1); exit 1; }; } + +echo "$as_me:$LINENO: checking build system type" >&5 +echo $ECHO_N "checking build system type... $ECHO_C" >&6 +if test "${ac_cv_build+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_build_alias=$build_alias +test -z "$ac_cv_build_alias" && + ac_cv_build_alias=`$ac_config_guess` +test -z "$ac_cv_build_alias" && + { { echo "$as_me:$LINENO: error: cannot guess build type; you must specify one" >&5 +echo "$as_me: error: cannot guess build type; you must specify one" >&2;} + { (exit 1); exit 1; }; } +ac_cv_build=`$ac_config_sub $ac_cv_build_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_build_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_build_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_build" >&5 +echo "${ECHO_T}$ac_cv_build" >&6 +build=$ac_cv_build +build_cpu=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +build_vendor=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +build_os=`echo $ac_cv_build | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + +echo "$as_me:$LINENO: checking host system type" >&5 +echo $ECHO_N "checking host system type... $ECHO_C" >&6 +if test "${ac_cv_host+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_host_alias=$host_alias +test -z "$ac_cv_host_alias" && + ac_cv_host_alias=$ac_cv_build_alias +ac_cv_host=`$ac_config_sub $ac_cv_host_alias` || + { { echo "$as_me:$LINENO: error: $ac_config_sub $ac_cv_host_alias failed" >&5 +echo "$as_me: error: $ac_config_sub $ac_cv_host_alias failed" >&2;} + { (exit 1); exit 1; }; } + +fi +echo "$as_me:$LINENO: result: $ac_cv_host" >&5 +echo "${ECHO_T}$ac_cv_host" >&6 +host=$ac_cv_host +host_cpu=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\1/'` +host_vendor=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\2/'` +host_os=`echo $ac_cv_host | sed 's/^\([^-]*\)-\([^-]*\)-\(.*\)$/\3/'` + + + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args. +set dummy ${ac_tool_prefix}gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "gcc", so it can be a program name with args. +set dummy gcc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="gcc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args. +set dummy ${ac_tool_prefix}cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="${ac_tool_prefix}cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_CC"; then + ac_ct_CC=$CC + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + CC=$ac_ct_CC +else + CC="$ac_cv_prog_CC" +fi + +fi +if test -z "$CC"; then + # Extract the first word of "cc", so it can be a program name with args. +set dummy cc; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else + ac_prog_rejected=no +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then + ac_prog_rejected=yes + continue + fi + ac_cv_prog_CC="cc" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +if test $ac_prog_rejected = yes; then + # We found a bogon in the path, so make sure we never use it. + set dummy $ac_cv_prog_CC + shift + if test $# != 0; then + # We chose a different compiler from the bogus one. + # However, it has the same basename, so the bogon will be chosen + # first if we set CC to just the basename; use the full file name. + shift + ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@" + fi +fi +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$CC"; then + if test -n "$ac_tool_prefix"; then + for ac_prog in cl + do + # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args. +set dummy $ac_tool_prefix$ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$CC"; then + ac_cv_prog_CC="$CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_CC="$ac_tool_prefix$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +CC=$ac_cv_prog_CC +if test -n "$CC"; then + echo "$as_me:$LINENO: result: $CC" >&5 +echo "${ECHO_T}$CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$CC" && break + done +fi +if test -z "$CC"; then + ac_ct_CC=$CC + for ac_prog in cl +do + # Extract the first word of "$ac_prog", so it can be a program name with args. +set dummy $ac_prog; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_CC+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_CC"; then + ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_CC="$ac_prog" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +ac_ct_CC=$ac_cv_prog_ac_ct_CC +if test -n "$ac_ct_CC"; then + echo "$as_me:$LINENO: result: $ac_ct_CC" >&5 +echo "${ECHO_T}$ac_ct_CC" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + test -n "$ac_ct_CC" && break +done + + CC=$ac_ct_CC +fi + +fi + + +test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&5 +echo "$as_me: error: no acceptable C compiler found in \$PATH +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + +# Provide some information about the compiler. +echo "$as_me:$LINENO:" \ + "checking for C compiler version" >&5 +ac_compiler=`set X $ac_compile; echo $2` +{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version &5\"") >&5 + (eval $ac_compiler --version &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v &5\"") >&5 + (eval $ac_compiler -v &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } +{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V &5\"") >&5 + (eval $ac_compiler -V &5) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } + +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +ac_clean_files_save=$ac_clean_files +ac_clean_files="$ac_clean_files a.out a.exe b.out" +# Try to create an executable without -o first, disregard a.out. +# It will help us diagnose broken compilers, and finding out an intuition +# of exeext. +echo "$as_me:$LINENO: checking for C compiler default output file name" >&5 +echo $ECHO_N "checking for C compiler default output file name... $ECHO_C" >&6 +ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'` +if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5 + (eval $ac_link_default) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # Find the output, starting from the most likely. This scheme is +# not robust to junk in `.', hence go to wildcards (a.*) only as a last +# resort. + +# Be careful to initialize this variable, since it used to be cached. +# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile. +ac_cv_exeext= +# b.out is created by i960 compilers. +for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out +do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) + ;; + conftest.$ac_ext ) + # This is the source file. + ;; + [ab].out ) + # We found the default executable, but exeext='' is most + # certainly right. + break;; + *.* ) + ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + # FIXME: I believe we export ac_cv_exeext for Libtool, + # but it would be cool to find out if it's true. Does anybody + # maintain Libtool? --akim. + export ac_cv_exeext + break;; + * ) + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: C compiler cannot create executables +See \`config.log' for more details." >&5 +echo "$as_me: error: C compiler cannot create executables +See \`config.log' for more details." >&2;} + { (exit 77); exit 77; }; } +fi + +ac_exeext=$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_file" >&5 +echo "${ECHO_T}$ac_file" >&6 + +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether the C compiler works" >&5 +echo $ECHO_N "checking whether the C compiler works... $ECHO_C" >&6 +# FIXME: These cross compiler hacks should be removed for Autoconf 3.0 +# If not cross compiling, check that we can run a simple program. +if test "$cross_compiling" != yes; then + if { ac_try='./$ac_file' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + cross_compiling=no + else + if test "$cross_compiling" = maybe; then + cross_compiling=yes + else + { { echo "$as_me:$LINENO: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot run C compiled programs. +If you meant to cross compile, use \`--host'. +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } + fi + fi +fi +echo "$as_me:$LINENO: result: yes" >&5 +echo "${ECHO_T}yes" >&6 + +rm -f a.out a.exe conftest$ac_cv_exeext b.out +ac_clean_files=$ac_clean_files_save +# Check the compiler produces executables we can run. If not, either +# the compiler is broken, or we cross compile. +echo "$as_me:$LINENO: checking whether we are cross compiling" >&5 +echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6 +echo "$as_me:$LINENO: result: $cross_compiling" >&5 +echo "${ECHO_T}$cross_compiling" >&6 + +echo "$as_me:$LINENO: checking for suffix of executables" >&5 +echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6 +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + # If both `conftest.exe' and `conftest' are `present' (well, observable) +# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will +# work properly (i.e., refer to `conftest.exe'), while it won't with +# `rm'. +for ac_file in conftest.exe conftest conftest.*; do + test -f "$ac_file" || continue + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;; + *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'` + export ac_cv_exeext + break;; + * ) break;; + esac +done +else + { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of executables: cannot compile and link +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest$ac_cv_exeext +echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5 +echo "${ECHO_T}$ac_cv_exeext" >&6 + +rm -f conftest.$ac_ext +EXEEXT=$ac_cv_exeext +ac_exeext=$EXEEXT +echo "$as_me:$LINENO: checking for suffix of object files" >&5 +echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6 +if test "${ac_cv_objext+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.o conftest.obj +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; then + for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do + case $ac_file in + *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;; + *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'` + break;; + esac +done +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&5 +echo "$as_me: error: cannot compute suffix of object files: cannot compile +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +rm -f conftest.$ac_cv_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_objext" >&5 +echo "${ECHO_T}$ac_cv_objext" >&6 +OBJEXT=$ac_cv_objext +ac_objext=$OBJEXT +echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5 +echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6 +if test "${ac_cv_c_compiler_gnu+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +#ifndef __GNUC__ + choke me +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_compiler_gnu=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_compiler_gnu=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_cv_c_compiler_gnu=$ac_compiler_gnu + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5 +echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6 +GCC=`test $ac_compiler_gnu = yes && echo yes` +ac_test_CFLAGS=${CFLAGS+set} +ac_save_CFLAGS=$CFLAGS +CFLAGS="-g" +echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5 +echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_g+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_g=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_prog_cc_g=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_g" >&6 +if test "$ac_test_CFLAGS" = set; then + CFLAGS=$ac_save_CFLAGS +elif test $ac_cv_prog_cc_g = yes; then + if test "$GCC" = yes; then + CFLAGS="-g -O2" + else + CFLAGS="-g" + fi +else + if test "$GCC" = yes; then + CFLAGS="-O2" + else + CFLAGS= + fi +fi +echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5 +echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6 +if test "${ac_cv_prog_cc_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_prog_cc_stdc=no +ac_save_CC=$CC +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include +/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */ +struct buf { int x; }; +FILE * (*rcsopen) (struct buf *, struct stat *, int); +static char *e (p, i) + char **p; + int i; +{ + return p[i]; +} +static char *f (char * (*g) (char **, int), char **p, ...) +{ + char *s; + va_list v; + va_start (v,p); + s = g (p, va_arg (v,int)); + va_end (v); + return s; +} + +/* OSF 4.0 Compaq cc is some sort of almost-ANSI by default. It has + function prototypes and stuff, but not '\xHH' hex character constants. + These don't provoke an error unfortunately, instead are silently treated + as 'x'. The following induces an error, until -std1 is added to get + proper ANSI mode. Curiously '\x00'!='x' always comes out true, for an + array size at least. It's necessary to write '\x00'==0 to get something + that's true only with -std1. */ +int osf4_cc_array ['\x00' == 0 ? 1 : -1]; + +int test (int i, double x); +struct s1 {int (*f) (int a);}; +struct s2 {int (*f) (double a);}; +int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int); +int argc; +char **argv; +int +main () +{ +return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1]; + ; + return 0; +} +_ACEOF +# Don't try gcc -ansi; that turns off useful extensions and +# breaks some systems' header files. +# AIX -qlanglvl=ansi +# Ultrix and OSF/1 -std1 +# HP-UX 10.20 and later -Ae +# HP-UX older versions -Aa -D_HPUX_SOURCE +# SVR4 -Xc -D__EXTENSIONS__ +for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__" +do + CC="$ac_save_CC $ac_arg" + rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_prog_cc_stdc=$ac_arg +break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext +done +rm -f conftest.$ac_ext conftest.$ac_objext +CC=$ac_save_CC + +fi + +case "x$ac_cv_prog_cc_stdc" in + x|xno) + echo "$as_me:$LINENO: result: none needed" >&5 +echo "${ECHO_T}none needed" >&6 ;; + *) + echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5 +echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6 + CC="$CC $ac_cv_prog_cc_stdc" ;; +esac + +# Some people use a C++ compiler to compile C. Since we use `exit', +# in C++ we need to declare it. In case someone uses the same compiler +# for both compiling C and C++ we need to have the C++ compiler decide +# the declaration of exit, since it's the most demanding environment. +cat >conftest.$ac_ext <<_ACEOF +#ifndef __cplusplus + choke me +#endif +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + for ac_declaration in \ + '' \ + 'extern "C" void std::exit (int) throw (); using std::exit;' \ + 'extern "C" void std::exit (int); using std::exit;' \ + 'extern "C" void exit (int) throw ();' \ + 'extern "C" void exit (int);' \ + 'void exit (int);' +do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +#include +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +continue +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_declaration +int +main () +{ +exit (42); + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done +rm -f conftest* +if test -n "$ac_declaration"; then + echo '#ifdef __cplusplus' >>confdefs.h + echo $ac_declaration >>confdefs.h + echo '#endif' >>confdefs.h +fi + +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +DEPDIR="${am__leading_dot}deps" + + ac_config_commands="$ac_config_commands depfiles" + + +am_make=${MAKE-make} +cat > confinc << 'END' +am__doit: + @echo done +.PHONY: am__doit +END +# If we don't find an include directive, just comment out the code. +echo "$as_me:$LINENO: checking for style of include used by $am_make" >&5 +echo $ECHO_N "checking for style of include used by $am_make... $ECHO_C" >&6 +am__include="#" +am__quote= +_am_result=none +# First try GNU make style include. +echo "include confinc" > confmf +# We grep out `Entering directory' and `Leaving directory' +# messages which can occur if `w' ends up in MAKEFLAGS. +# In particular we don't look at `^make:' because GNU make might +# be invoked under some other name (usually "gmake"), in which +# case it prints its new name instead of `make'. +if test "`$am_make -s -f confmf 2> /dev/null | grep -v 'ing directory'`" = "done"; then + am__include=include + am__quote= + _am_result=GNU +fi +# Now try BSD make style include. +if test "$am__include" = "#"; then + echo '.include "confinc"' > confmf + if test "`$am_make -s -f confmf 2> /dev/null`" = "done"; then + am__include=.include + am__quote="\"" + _am_result=BSD + fi +fi + + +echo "$as_me:$LINENO: result: $_am_result" >&5 +echo "${ECHO_T}$_am_result" >&6 +rm -f confinc confmf + +# Check whether --enable-dependency-tracking or --disable-dependency-tracking was given. +if test "${enable_dependency_tracking+set}" = set; then + enableval="$enable_dependency_tracking" + +fi; +if test "x$enable_dependency_tracking" != xno; then + am_depcomp="$ac_aux_dir/depcomp" + AMDEPBACKSLASH='\' +fi + + +if test "x$enable_dependency_tracking" != xno; then + AMDEP_TRUE= + AMDEP_FALSE='#' +else + AMDEP_TRUE='#' + AMDEP_FALSE= +fi + + + + +depcc="$CC" am_compiler_list= + +echo "$as_me:$LINENO: checking dependency style of $depcc" >&5 +echo $ECHO_N "checking dependency style of $depcc... $ECHO_C" >&6 +if test "${am_cv_CC_dependencies_compiler_type+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then + # We make a subdir and do the tests there. Otherwise we can end up + # making bogus files that we don't know about and never remove. For + # instance it was reported that on HP-UX the gcc test will end up + # making a dummy file named `D' -- because `-MD' means `put the output + # in D'. + mkdir conftest.dir + # Copy depcomp to subdir because otherwise we won't find it if we're + # using a relative directory. + cp "$am_depcomp" conftest.dir + cd conftest.dir + # We will build objects and dependencies in a subdirectory because + # it helps to detect inapplicable dependency modes. For instance + # both Tru64's cc and ICC support -MD to output dependencies as a + # side effect of compilation, but ICC will put the dependencies in + # the current directory while Tru64 will put them in the object + # directory. + mkdir sub + + am_cv_CC_dependencies_compiler_type=none + if test "$am_compiler_list" = ""; then + am_compiler_list=`sed -n 's/^#*\([a-zA-Z0-9]*\))$/\1/p' < ./depcomp` + fi + for depmode in $am_compiler_list; do + # Setup a source with many dependencies, because some compilers + # like to wrap large dependency lists on column 80 (with \), and + # we should not choose a depcomp mode which is confused by this. + # + # We need to recreate these files for each test, as the compiler may + # overwrite some of them when testing with obscure command lines. + # This happens at least with the AIX C compiler. + : > sub/conftest.c + for i in 1 2 3 4 5 6; do + echo '#include "conftst'$i'.h"' >> sub/conftest.c + # Using `: > sub/conftst$i.h' creates only sub/conftst1.h with + # Solaris 8's {/usr,}/bin/sh. + touch sub/conftst$i.h + done + echo "${am__include} ${am__quote}sub/conftest.Po${am__quote}" > confmf + + case $depmode in + nosideeffect) + # after this tag, mechanisms are not by side-effect, so they'll + # only be used when explicitly requested + if test "x$enable_dependency_tracking" = xyes; then + continue + else + break + fi + ;; + none) break ;; + esac + # We check with `-c' and `-o' for the sake of the "dashmstdout" + # mode. It turns out that the SunPro C++ compiler does not properly + # handle `-M -o', and we need to detect this. + if depmode=$depmode \ + source=sub/conftest.c object=sub/conftest.${OBJEXT-o} \ + depfile=sub/conftest.Po tmpdepfile=sub/conftest.TPo \ + $SHELL ./depcomp $depcc -c -o sub/conftest.${OBJEXT-o} sub/conftest.c \ + >/dev/null 2>conftest.err && + grep sub/conftst6.h sub/conftest.Po > /dev/null 2>&1 && + grep sub/conftest.${OBJEXT-o} sub/conftest.Po > /dev/null 2>&1 && + ${MAKE-make} -s -f confmf > /dev/null 2>&1; then + # icc doesn't choke on unknown options, it will just issue warnings + # or remarks (even with -Werror). So we grep stderr for any message + # that says an option was ignored or not supported. + # When given -MP, icc 7.0 and 7.1 complain thusly: + # icc: Command line warning: ignoring option '-M'; no argument required + # The diagnosis changed in icc 8.0: + # icc: Command line remark: option '-MP' not supported + if (grep 'ignoring option' conftest.err || + grep 'not supported' conftest.err) >/dev/null 2>&1; then :; else + am_cv_CC_dependencies_compiler_type=$depmode + break + fi + fi + done + + cd .. + rm -rf conftest.dir +else + am_cv_CC_dependencies_compiler_type=none +fi + +fi +echo "$as_me:$LINENO: result: $am_cv_CC_dependencies_compiler_type" >&5 +echo "${ECHO_T}$am_cv_CC_dependencies_compiler_type" >&6 +CCDEPMODE=depmode=$am_cv_CC_dependencies_compiler_type + + + +if + test "x$enable_dependency_tracking" != xno \ + && test "$am_cv_CC_dependencies_compiler_type" = gcc3; then + am__fastdepCC_TRUE= + am__fastdepCC_FALSE='#' +else + am__fastdepCC_TRUE='#' + am__fastdepCC_FALSE= +fi + + +if test "$GCC" = yes; then + +cat >>confdefs.h <<\_ACEOF +#define UNUSED __attribute__ ((unused)) +_ACEOF + +else + +cat >>confdefs.h <<\_ACEOF +#define UNUSED +_ACEOF + +fi +# Find a good install program. We prefer a C program (faster), +# so one script is as good as another. But avoid the broken or +# incompatible versions: +# SysV /etc/install, /usr/sbin/install +# SunOS /usr/etc/install +# IRIX /sbin/install +# AIX /bin/install +# AmigaOS /C/install, which installs bootblocks on floppy discs +# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag +# AFS /usr/afsws/bin/install, which mishandles nonexistent args +# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff" +# OS/2's system install, which has a completely different semantic +# ./install, which can be erroneously created by make from ./install.sh. +echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5 +echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6 +if test -z "$INSTALL"; then +if test "${ac_cv_path_install+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + # Account for people who put trailing slashes in PATH elements. +case $as_dir/ in + ./ | .// | /cC/* | \ + /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \ + ?:\\/os2\\/install\\/* | ?:\\/OS2\\/INSTALL\\/* | \ + /usr/ucb/* ) ;; + *) + # OSF1 and SCO ODT 3.0 have their own names for install. + # Don't use installbsd from OSF since it installs stuff as root + # by default. + for ac_prog in ginstall scoinst install; do + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then + if test $ac_prog = install && + grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # AIX install. It has an incompatible calling convention. + : + elif test $ac_prog = install && + grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then + # program-specific install script used by HP pwplus--don't use. + : + else + ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c" + break 3 + fi + fi + done + done + ;; +esac +done + + +fi + if test "${ac_cv_path_install+set}" = set; then + INSTALL=$ac_cv_path_install + else + # As a last resort, use the slow shell script. We don't cache a + # path for INSTALL within a source directory, because that will + # break other packages using the cache if that directory is + # removed, or if the path is relative. + INSTALL=$ac_install_sh + fi +fi +echo "$as_me:$LINENO: result: $INSTALL" >&5 +echo "${ECHO_T}$INSTALL" >&6 + +# Use test -z because SunOS4 sh mishandles braces in ${var-val}. +# It thinks the first close brace ends the variable substitution. +test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}' + +test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}' + +test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644' + +if test -n "$ac_tool_prefix"; then + # Extract the first word of "${ac_tool_prefix}ranlib", so it can be a program name with args. +set dummy ${ac_tool_prefix}ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$RANLIB"; then + ac_cv_prog_RANLIB="$RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_RANLIB="${ac_tool_prefix}ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + +fi +fi +RANLIB=$ac_cv_prog_RANLIB +if test -n "$RANLIB"; then + echo "$as_me:$LINENO: result: $RANLIB" >&5 +echo "${ECHO_T}$RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +fi +if test -z "$ac_cv_prog_RANLIB"; then + ac_ct_RANLIB=$RANLIB + # Extract the first word of "ranlib", so it can be a program name with args. +set dummy ranlib; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_prog_ac_ct_RANLIB+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if test -n "$ac_ct_RANLIB"; then + ac_cv_prog_ac_ct_RANLIB="$ac_ct_RANLIB" # Let the user override the test. +else +as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_prog_ac_ct_RANLIB="ranlib" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + test -z "$ac_cv_prog_ac_ct_RANLIB" && ac_cv_prog_ac_ct_RANLIB=":" +fi +fi +ac_ct_RANLIB=$ac_cv_prog_ac_ct_RANLIB +if test -n "$ac_ct_RANLIB"; then + echo "$as_me:$LINENO: result: $ac_ct_RANLIB" >&5 +echo "${ECHO_T}$ac_ct_RANLIB" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + + RANLIB=$ac_ct_RANLIB +else + RANLIB="$ac_cv_prog_RANLIB" +fi + + +# Extract the first word of "perl", so it can be a program name with args. +set dummy perl; ac_word=$2 +echo "$as_me:$LINENO: checking for $ac_word" >&5 +echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6 +if test "${ac_cv_path_PerlCmd+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + case $PerlCmd in + [\\/]* | ?:[\\/]*) + ac_cv_path_PerlCmd="$PerlCmd" # Let the user override the test with a path. + ;; + *) + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for ac_exec_ext in '' $ac_executable_extensions; do + if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then + ac_cv_path_PerlCmd="$as_dir/$ac_word$ac_exec_ext" + echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5 + break 2 + fi +done +done + + ;; +esac +fi +PerlCmd=$ac_cv_path_PerlCmd + +if test -n "$PerlCmd"; then + echo "$as_me:$LINENO: result: $PerlCmd" >&5 +echo "${ECHO_T}$PerlCmd" >&6 +else + echo "$as_me:$LINENO: result: no" >&5 +echo "${ECHO_T}no" >&6 +fi + +if test -n "$PerlCmd"; then + if $PerlCmd -e 'require 5.004'; then : + else + echo "$as_me:$LINENO: result: You need Perl version 5.004 or higher for the Perl module" >&5 +echo "${ECHO_T}You need Perl version 5.004 or higher for the Perl module" >&6 + with_perl="no" + fi +fi + +if test -z "$PerlCmd"; then + echo "$as_me:$LINENO: result: No suitable Perl found -- will not build Perl module" >&5 +echo "${ECHO_T}No suitable Perl found -- will not build Perl module" >&6 + echo "$as_me:$LINENO: result: You may set the PerlCmd environment variable to point to + a suitable perl binary" >&5 +echo "${ECHO_T}You may set the PerlCmd environment variable to point to + a suitable perl binary" >&6 + with_perl="no" +fi + +if test "$with_forester" != "no"; then + if test -f $srcdir/RNAforester/Makefile.am; then + + +subdirs="$subdirs RNAforester" + + else + { echo "$as_me:$LINENO: WARNING: RNAforester subdirectory does not exist" >&5 +echo "$as_me: WARNING: RNAforester subdirectory does not exist" >&2;} + with_forester="no" + fi +fi + +if test "$with_kinfold" != "no"; then + if test -f $srcdir/Kinfold/Makefile.am; then + + +subdirs="$subdirs Kinfold" + + else + { echo "$as_me:$LINENO: WARNING: Kinfold subdirectory does not exist" >&5 +echo "$as_me: WARNING: Kinfold subdirectory does not exist" >&2;} + with_kinfold="no" + fi +fi + + + +if test "$with_perl" != "no"; then + MAKE_PERL_EXT_TRUE= + MAKE_PERL_EXT_FALSE='#' +else + MAKE_PERL_EXT_TRUE='#' + MAKE_PERL_EXT_FALSE= +fi + + + + +if test "$with_cluster" = "yes"; then + MAKE_CLUSTER_TRUE= + MAKE_CLUSTER_FALSE='#' +else + MAKE_CLUSTER_TRUE='#' + MAKE_CLUSTER_FALSE= +fi + + + + +if test "$with_forester" != "no"; then + MAKE_FORESTER_TRUE= + MAKE_FORESTER_FALSE='#' +else + MAKE_FORESTER_TRUE='#' + MAKE_FORESTER_FALSE= +fi + + + + +if test "$with_kinfold" != "no"; then + MAKE_KINFOLD_TRUE= + MAKE_KINFOLD_FALSE='#' +else + MAKE_KINFOLD_TRUE='#' + MAKE_KINFOLD_FALSE= +fi + + + + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu +echo "$as_me:$LINENO: checking how to run the C preprocessor" >&5 +echo $ECHO_N "checking how to run the C preprocessor... $ECHO_C" >&6 +# On Suns, sometimes $CPP names a directory. +if test -n "$CPP" && test -d "$CPP"; then + CPP= +fi +if test -z "$CPP"; then + if test "${ac_cv_prog_CPP+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + # Double quotes because CPP needs to be expanded + for CPP in "$CC -E" "$CC -E -traditional-cpp" "/lib/cpp" + do + ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + break +fi + + done + ac_cv_prog_CPP=$CPP + +fi + CPP=$ac_cv_prog_CPP +else + ac_cv_prog_CPP=$CPP +fi +echo "$as_me:$LINENO: result: $CPP" >&5 +echo "${ECHO_T}$CPP" >&6 +ac_preproc_ok=false +for ac_c_preproc_warn_flag in '' yes +do + # Use a header file that comes with gcc, so configuring glibc + # with a fresh cross-compiler works. + # Prefer to if __STDC__ is defined, since + # exists even on freestanding compilers. + # On the NeXT, cc -E runs the code through the compiler's parser, + # not just through cpp. "Syntax error" is here to catch this case. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifdef __STDC__ +# include +#else +# include +#endif + Syntax error +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + : +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Broken: fails on valid input. +continue +fi +rm -f conftest.err conftest.$ac_ext + + # OK, works on sane cases. Now check whether non-existent headers + # can be detected and how. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + # Broken: success on invalid input. +continue +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + # Passes both tests. +ac_preproc_ok=: +break +fi +rm -f conftest.err conftest.$ac_ext + +done +# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped. +rm -f conftest.err conftest.$ac_ext +if $ac_preproc_ok; then + : +else + { { echo "$as_me:$LINENO: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&5 +echo "$as_me: error: C preprocessor \"$CPP\" fails sanity check +See \`config.log' for more details." >&2;} + { (exit 1); exit 1; }; } +fi + +ac_ext=c +ac_cpp='$CPP $CPPFLAGS' +ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5' +ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5' +ac_compiler_gnu=$ac_cv_c_compiler_gnu + + +echo "$as_me:$LINENO: checking for egrep" >&5 +echo $ECHO_N "checking for egrep... $ECHO_C" >&6 +if test "${ac_cv_prog_egrep+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + if echo a | (grep -E '(a|b)') >/dev/null 2>&1 + then ac_cv_prog_egrep='grep -E' + else ac_cv_prog_egrep='egrep' + fi +fi +echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5 +echo "${ECHO_T}$ac_cv_prog_egrep" >&6 + EGREP=$ac_cv_prog_egrep + + +echo "$as_me:$LINENO: checking for ANSI C header files" >&5 +echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6 +if test "${ac_cv_header_stdc+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#include +#include +#include + +int +main () +{ + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_header_stdc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_header_stdc=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext + +if test $ac_cv_header_stdc = yes; then + # SunOS 4.x string.h does not declare mem*, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "memchr" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI. + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include + +_ACEOF +if (eval "$ac_cpp conftest.$ac_ext") 2>&5 | + $EGREP "free" >/dev/null 2>&1; then + : +else + ac_cv_header_stdc=no +fi +rm -f conftest* + +fi + +if test $ac_cv_header_stdc = yes; then + # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi. + if test "$cross_compiling" = yes; then + : +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include +#if ((' ' & 0x0FF) == 0x020) +# define ISLOWER(c) ('a' <= (c) && (c) <= 'z') +# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c)) +#else +# define ISLOWER(c) \ + (('a' <= (c) && (c) <= 'i') \ + || ('j' <= (c) && (c) <= 'r') \ + || ('s' <= (c) && (c) <= 'z')) +# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c)) +#endif + +#define XOR(e, f) (((e) && !(f)) || (!(e) && (f))) +int +main () +{ + int i; + for (i = 0; i < 256; i++) + if (XOR (islower (i), ISLOWER (i)) + || toupper (i) != TOUPPER (i)) + exit(2); + exit (0); +} +_ACEOF +rm -f conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && { ac_try='./conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + : +else + echo "$as_me: program exited with status $ac_status" >&5 +echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +( exit $ac_status ) +ac_cv_header_stdc=no +fi +rm -f core *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext +fi +fi +fi +echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5 +echo "${ECHO_T}$ac_cv_header_stdc" >&6 +if test $ac_cv_header_stdc = yes; then + +cat >>confdefs.h <<\_ACEOF +#define STDC_HEADERS 1 +_ACEOF + +fi + +# On IRIX 5.3, sys/types and inttypes.h are conflicting. + + + + + + + + + +for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \ + inttypes.h stdint.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default + +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_Header=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_Header=no" +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + + + + +for ac_header in malloc.h strings.h unistd.h +do +as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh` +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 +else + # Is the header compilable? +echo "$as_me:$LINENO: checking $ac_header usability" >&5 +echo $ECHO_N "checking $ac_header usability... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +#include <$ac_header> +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_header_compiler=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_header_compiler=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_compiler" >&5 +echo "${ECHO_T}$ac_header_compiler" >&6 + +# Is the header present? +echo "$as_me:$LINENO: checking $ac_header presence" >&5 +echo $ECHO_N "checking $ac_header presence... $ECHO_C" >&6 +cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#include <$ac_header> +_ACEOF +if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5 + (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } >/dev/null; then + if test -s conftest.err; then + ac_cpp_err=$ac_c_preproc_warn_flag + ac_cpp_err=$ac_cpp_err$ac_c_werror_flag + else + ac_cpp_err= + fi +else + ac_cpp_err=yes +fi +if test -z "$ac_cpp_err"; then + ac_header_preproc=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + + ac_header_preproc=no +fi +rm -f conftest.err conftest.$ac_ext +echo "$as_me:$LINENO: result: $ac_header_preproc" >&5 +echo "${ECHO_T}$ac_header_preproc" >&6 + +# So? What about this header? +case $ac_header_compiler:$ac_header_preproc:$ac_c_preproc_warn_flag in + yes:no: ) + { echo "$as_me:$LINENO: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&5 +echo "$as_me: WARNING: $ac_header: accepted by the compiler, rejected by the preprocessor!" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the compiler's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the compiler's result" >&2;} + ac_header_preproc=yes + ;; + no:yes:* ) + { echo "$as_me:$LINENO: WARNING: $ac_header: present but cannot be compiled" >&5 +echo "$as_me: WARNING: $ac_header: present but cannot be compiled" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: check for missing prerequisite headers?" >&5 +echo "$as_me: WARNING: $ac_header: check for missing prerequisite headers?" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: see the Autoconf documentation" >&5 +echo "$as_me: WARNING: $ac_header: see the Autoconf documentation" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&5 +echo "$as_me: WARNING: $ac_header: section \"Present But Cannot Be Compiled\"" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: proceeding with the preprocessor's result" >&5 +echo "$as_me: WARNING: $ac_header: proceeding with the preprocessor's result" >&2;} + { echo "$as_me:$LINENO: WARNING: $ac_header: in the future, the compiler will take precedence" >&5 +echo "$as_me: WARNING: $ac_header: in the future, the compiler will take precedence" >&2;} + ( + cat <<\_ASBOX +## ----------------------------------- ## +## Report this to rna@tbi.univie.ac.at ## +## ----------------------------------- ## +_ASBOX + ) | + sed "s/^/$as_me: WARNING: /" >&2 + ;; +esac +echo "$as_me:$LINENO: checking for $ac_header" >&5 +echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6 +if eval "test \"\${$as_ac_Header+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + eval "$as_ac_Header=\$ac_header_preproc" +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6 + +fi +if test `eval echo '${'$as_ac_Header'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1 +_ACEOF + +fi + +done + + +echo "$as_me:$LINENO: checking for an ANSI C-conforming const" >&5 +echo $ECHO_N "checking for an ANSI C-conforming const... $ECHO_C" >&6 +if test "${ac_cv_c_const+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ + +int +main () +{ +/* FIXME: Include the comments suggested by Paul. */ +#ifndef __cplusplus + /* Ultrix mips cc rejects this. */ + typedef int charset[2]; + const charset x; + /* SunOS 4.1.1 cc rejects this. */ + char const *const *ccp; + char **p; + /* NEC SVR4.0.2 mips cc rejects this. */ + struct point {int x, y;}; + static struct point const zero = {0,0}; + /* AIX XL C 1.02.0.0 rejects this. + It does not let you subtract one const X* pointer from another in + an arm of an if-expression whose if-part is not a constant + expression */ + const char *g = "string"; + ccp = &g + (g ? g-g : 0); + /* HPUX 7.0 cc rejects these. */ + ++ccp; + p = (char**) ccp; + ccp = (char const *const *) p; + { /* SCO 3.2v4 cc rejects this. */ + char *t; + char const *s = 0 ? (char *) 0 : (char const *) 0; + + *t++ = 0; + } + { /* Someone thinks the Sun supposedly-ANSI compiler will reject this. */ + int x[] = {25, 17}; + const int *foo = &x[0]; + ++foo; + } + { /* Sun SC1.0 ANSI compiler rejects this -- but not the above. */ + typedef const int *iptr; + iptr p = 0; + ++p; + } + { /* AIX XL C 1.02.0.0 rejects this saying + "k.c", line 2.27: 1506-025 (S) Operand must be a modifiable lvalue. */ + struct s { int j; const int *ap[3]; }; + struct s *b; b->j = 5; + } + { /* ULTRIX-32 V3.1 (Rev 9) vcc rejects this */ + const int foo = 10; + } +#endif + + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_c_const=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_c_const=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_c_const" >&5 +echo "${ECHO_T}$ac_cv_c_const" >&6 +if test $ac_cv_c_const = no; then + +cat >>confdefs.h <<\_ACEOF +#define const +_ACEOF + +fi + +echo "$as_me:$LINENO: checking for size_t" >&5 +echo $ECHO_N "checking for size_t... $ECHO_C" >&6 +if test "${ac_cv_type_size_t+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +$ac_includes_default +int +main () +{ +if ((size_t *) 0) + return 0; +if (sizeof (size_t)) + return 0; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_type_size_t=yes +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +ac_cv_type_size_t=no +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: $ac_cv_type_size_t" >&5 +echo "${ECHO_T}$ac_cv_type_size_t" >&6 +if test $ac_cv_type_size_t = yes; then + : +else + +cat >>confdefs.h <<_ACEOF +#define size_t unsigned +_ACEOF + +fi + +echo "$as_me:$LINENO: checking for inline" >&5 +echo $ECHO_N "checking for inline... $ECHO_C" >&6 +if test "${ac_cv_c_inline+set}" = set; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + ac_cv_c_inline=no +for ac_kw in inline __inline__ __inline; do + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +#ifndef __cplusplus +typedef int foo_t; +static $ac_kw foo_t static_foo () {return 0; } +$ac_kw foo_t foo () {return 0; } +#endif + +_ACEOF +rm -f conftest.$ac_objext +if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5 + (eval $ac_compile) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest.$ac_objext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + ac_cv_c_inline=$ac_kw; break +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +fi +rm -f conftest.err conftest.$ac_objext conftest.$ac_ext +done + +fi +echo "$as_me:$LINENO: result: $ac_cv_c_inline" >&5 +echo "${ECHO_T}$ac_cv_c_inline" >&6 + + +case $ac_cv_c_inline in + inline | yes) ;; + *) + case $ac_cv_c_inline in + no) ac_val=;; + *) ac_val=$ac_cv_c_inline;; + esac + cat >>confdefs.h <<_ACEOF +#ifndef __cplusplus +#define inline $ac_val +#endif +_ACEOF + ;; +esac + + + + + + +for ac_func in strdup strstr strchr erand48 +do +as_ac_var=`echo "ac_cv_func_$ac_func" | $as_tr_sh` +echo "$as_me:$LINENO: checking for $ac_func" >&5 +echo $ECHO_N "checking for $ac_func... $ECHO_C" >&6 +if eval "test \"\${$as_ac_var+set}\" = set"; then + echo $ECHO_N "(cached) $ECHO_C" >&6 +else + cat >conftest.$ac_ext <<_ACEOF +/* confdefs.h. */ +_ACEOF +cat confdefs.h >>conftest.$ac_ext +cat >>conftest.$ac_ext <<_ACEOF +/* end confdefs.h. */ +/* Define $ac_func to an innocuous variant, in case declares $ac_func. + For example, HP-UX 11i declares gettimeofday. */ +#define $ac_func innocuous_$ac_func + +/* System header to define __stub macros and hopefully few prototypes, + which can conflict with char $ac_func (); below. + Prefer to if __STDC__ is defined, since + exists even on freestanding compilers. */ + +#ifdef __STDC__ +# include +#else +# include +#endif + +#undef $ac_func + +/* Override any gcc2 internal prototype to avoid an error. */ +#ifdef __cplusplus +extern "C" +{ +#endif +/* We use char because int might match the return type of a gcc2 + builtin and then its argument prototype would still apply. */ +char $ac_func (); +/* The GNU C library defines this for functions which it implements + to always fail with ENOSYS. Some functions are actually named + something starting with __ and the normal name is an alias. */ +#if defined (__stub_$ac_func) || defined (__stub___$ac_func) +choke me +#else +char (*f) () = $ac_func; +#endif +#ifdef __cplusplus +} +#endif + +int +main () +{ +return f != $ac_func; + ; + return 0; +} +_ACEOF +rm -f conftest.$ac_objext conftest$ac_exeext +if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5 + (eval $ac_link) 2>conftest.er1 + ac_status=$? + grep -v '^ *+' conftest.er1 >conftest.err + rm -f conftest.er1 + cat conftest.err >&5 + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); } && + { ac_try='test -z "$ac_c_werror_flag" + || test ! -s conftest.err' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; } && + { ac_try='test -s conftest$ac_exeext' + { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5 + (eval $ac_try) 2>&5 + ac_status=$? + echo "$as_me:$LINENO: \$? = $ac_status" >&5 + (exit $ac_status); }; }; then + eval "$as_ac_var=yes" +else + echo "$as_me: failed program was:" >&5 +sed 's/^/| /' conftest.$ac_ext >&5 + +eval "$as_ac_var=no" +fi +rm -f conftest.err conftest.$ac_objext \ + conftest$ac_exeext conftest.$ac_ext +fi +echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_var'}'`" >&5 +echo "${ECHO_T}`eval echo '${'$as_ac_var'}'`" >&6 +if test `eval echo '${'$as_ac_var'}'` = yes; then + cat >>confdefs.h <<_ACEOF +#define `echo "HAVE_$ac_func" | $as_tr_cpp` 1 +_ACEOF + +fi +done + + + ac_config_files="$ac_config_files Makefile ViennaRNA.spec Utils/Makefile Progs/Makefile lib/Makefile man/Makefile Cluster/Makefile H/Makefile Perl/Makefile man/RNAheat.1 man/RNAsubopt.1 man/RNAdistance.1 man/RNAinverse.1 man/RNAeval.1 man/RNAfold.1 man/RNApdist.1 man/RNAplot.1 man/RNALfold.1 man/RNAalifold.1 man/RNAduplex.1 man/RNAcofold.1 man/RNAplfold.1" + +cat >confcache <<\_ACEOF +# This file is a shell script that caches the results of configure +# tests run on this system so they can be shared between configure +# scripts and configure runs, see configure's option --config-cache. +# It is not useful on other systems. If it contains results you don't +# want to keep, you may remove or edit it. +# +# config.status only pays attention to the cache file if you give it +# the --recheck option to rerun configure. +# +# `ac_cv_env_foo' variables (set or unset) will be overridden when +# loading this file, other *unset* `ac_cv_foo' will be assigned the +# following values. + +_ACEOF + +# The following way of writing the cache mishandles newlines in values, +# but we know of no workaround that is simple, portable, and efficient. +# So, don't put newlines in cache variables' values. +# Ultrix sh set writes to stderr and can't be redirected directly, +# and sets the high bit in the cache file unless we assign to the vars. +{ + (set) 2>&1 | + case `(ac_space=' '; set | grep ac_space) 2>&1` in + *ac_space=\ *) + # `set' does not quote correctly, so add quotes (double-quote + # substitution turns \\\\ into \\, and sed turns \\ into \). + sed -n \ + "s/'/'\\\\''/g; + s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='\\2'/p" + ;; + *) + # `set' quotes correctly as required by POSIX, so do not add quotes. + sed -n \ + "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p" + ;; + esac; +} | + sed ' + t clear + : clear + s/^\([^=]*\)=\(.*[{}].*\)$/test "${\1+set}" = set || &/ + t end + /^ac_cv_env/!s/^\([^=]*\)=\(.*\)$/\1=${\1=\2}/ + : end' >>confcache +if diff $cache_file confcache >/dev/null 2>&1; then :; else + if test -w $cache_file; then + test "x$cache_file" != "x/dev/null" && echo "updating cache $cache_file" + cat confcache >$cache_file + else + echo "not updating unwritable cache $cache_file" + fi +fi +rm -f confcache + +test "x$prefix" = xNONE && prefix=$ac_default_prefix +# Let make expand exec_prefix. +test "x$exec_prefix" = xNONE && exec_prefix='${prefix}' + +# VPATH may cause trouble with some makes, so we remove $(srcdir), +# ${srcdir} and @srcdir@ from VPATH if srcdir is ".", strip leading and +# trailing colons and then remove the whole line if VPATH becomes empty +# (actually we leave an empty line to preserve line numbers). +if test "x$srcdir" = x.; then + ac_vpsub='/^[ ]*VPATH[ ]*=/{ +s/:*\$(srcdir):*/:/; +s/:*\${srcdir}:*/:/; +s/:*@srcdir@:*/:/; +s/^\([^=]*=[ ]*\):*/\1/; +s/:*$//; +s/^[^=]*=[ ]*$//; +}' +fi + +DEFS=-DHAVE_CONFIG_H + +ac_libobjs= +ac_ltlibobjs= +for ac_i in : $LIBOBJS; do test "x$ac_i" = x: && continue + # 1. Remove the extension, and $U if already installed. + ac_i=`echo "$ac_i" | + sed 's/\$U\././;s/\.o$//;s/\.obj$//'` + # 2. 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Look in the path if we contain no path at all + # relative or not. + case $0 in + *[\\/]* ) as_myself=$0 ;; + *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in $PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break +done + + ;; + esac + # We did not find ourselves, most probably we were run as `sh COMMAND' + # in which case we are not to be found in the path. + if test "x$as_myself" = x; then + as_myself=$0 + fi + if test ! -f "$as_myself"; then + { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5 +echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;} + { (exit 1); exit 1; }; } + fi + case $CONFIG_SHELL in + '') + as_save_IFS=$IFS; IFS=$PATH_SEPARATOR +for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH +do + IFS=$as_save_IFS + test -z "$as_dir" && as_dir=. + for as_base in sh bash ksh sh5; do + case $as_dir in + /*) + if ("$as_dir/$as_base" -c ' + as_lineno_1=$LINENO + as_lineno_2=$LINENO + as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null` + test "x$as_lineno_1" != "x$as_lineno_2" && + test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then + $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; } + $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; } + CONFIG_SHELL=$as_dir/$as_base + export CONFIG_SHELL + exec "$CONFIG_SHELL" "$0" ${1+"$@"} + fi;; + esac + done +done +;; + esac + + # Create $as_me.lineno as a copy of $as_myself, but with $LINENO + # uniformly replaced by the line number. The first 'sed' inserts a + # line-number line before each line; the second 'sed' does the real + # work. The second script uses 'N' to pair each line-number line + # with the numbered line, and appends trailing '-' during + # substitution so that $LINENO is not a special case at line end. + # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the + # second 'sed' script. Blame Lee E. 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Autoconf is especially sensible to this). + . ./$as_me.lineno + # Exit status is that of the last command. + exit +} + + +case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in + *c*,-n*) ECHO_N= ECHO_C=' +' ECHO_T=' ' ;; + *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;; + *) ECHO_N= ECHO_C='\c' ECHO_T= ;; +esac + +if expr a : '\(a\)' >/dev/null 2>&1; then + as_expr=expr +else + as_expr=false +fi + +rm -f conf$$ conf$$.exe conf$$.file +echo >conf$$.file +if ln -s conf$$.file conf$$ 2>/dev/null; then + # We could just check for DJGPP; but this test a) works b) is more generic + # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04). + if test -f conf$$.exe; then + # Don't use ln at all; we don't have any links + as_ln_s='cp -p' + else + as_ln_s='ln -s' + fi +elif ln conf$$.file conf$$ 2>/dev/null; then + as_ln_s=ln +else + as_ln_s='cp -p' +fi +rm -f conf$$ conf$$.exe conf$$.file + +if mkdir -p . 2>/dev/null; then + as_mkdir_p=: +else + test -d ./-p && rmdir ./-p + as_mkdir_p=false +fi + +as_executable_p="test -f" + +# Sed expression to map a string onto a valid CPP name. +as_tr_cpp="eval sed 'y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g'" + +# Sed expression to map a string onto a valid variable name. +as_tr_sh="eval sed 'y%*+%pp%;s%[^_$as_cr_alnum]%_%g'" + + +# IFS +# We need space, tab and new line, in precisely that order. +as_nl=' +' +IFS=" $as_nl" + +# CDPATH. +$as_unset CDPATH + +exec 6>&1 + +# Open the log real soon, to keep \$[0] and so on meaningful, and to +# report actual input values of CONFIG_FILES etc. instead of their +# values after options handling. Logging --version etc. is OK. +exec 5>>config.log +{ + echo + sed 'h;s/./-/g;s/^.../## /;s/...$/ ##/;p;x;p;x' <<_ASBOX +## Running $as_me. ## +_ASBOX +} >&5 +cat >&5 <<_CSEOF + +This file was extended by ViennaRNA $as_me 1.6, which was +generated by GNU Autoconf 2.59. Invocation command line was + + CONFIG_FILES = $CONFIG_FILES + CONFIG_HEADERS = $CONFIG_HEADERS + CONFIG_LINKS = $CONFIG_LINKS + CONFIG_COMMANDS = $CONFIG_COMMANDS + $ $0 $@ + +_CSEOF +echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5 +echo >&5 +_ACEOF + +# Files that config.status was made for. +if test -n "$ac_config_files"; then + echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_headers"; then + echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_links"; then + echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS +fi + +if test -n "$ac_config_commands"; then + echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS +fi + +cat >>$CONFIG_STATUS <<\_ACEOF + +ac_cs_usage="\ +\`$as_me' instantiates files from templates according to the +current configuration. + +Usage: $0 [OPTIONS] [FILE]... + + -h, --help print this help, then exit + -V, --version print version number, then exit + -q, --quiet do not print progress messages + -d, --debug don't remove temporary files + --recheck update $as_me by reconfiguring in the same conditions + --file=FILE[:TEMPLATE] + instantiate the configuration file FILE + --header=FILE[:TEMPLATE] + instantiate the configuration header FILE + +Configuration files: +$config_files + +Configuration headers: +$config_headers + +Configuration commands: +$config_commands + +Report bugs to ." +_ACEOF + +cat >>$CONFIG_STATUS <<_ACEOF +ac_cs_version="\\ +ViennaRNA config.status 1.6 +configured by $0, generated by GNU Autoconf 2.59, + with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\" + +Copyright (C) 2003 Free Software Foundation, Inc. +This config.status script is free software; the Free Software Foundation +gives unlimited permission to copy, distribute and modify it." +srcdir=$srcdir +INSTALL="$INSTALL" +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF +# If no file are specified by the user, then we need to provide default +# value. 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Set only those that are not. +# We use the long form for the default assignment because of an extremely +# bizarre bug on SunOS 4.1.3. +if $ac_need_defaults; then + test "${CONFIG_FILES+set}" = set || CONFIG_FILES=$config_files + test "${CONFIG_HEADERS+set}" = set || CONFIG_HEADERS=$config_headers + test "${CONFIG_COMMANDS+set}" = set || CONFIG_COMMANDS=$config_commands +fi + +# Have a temporary directory for convenience. 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The first handles `#define' +# templates, and the second `#undef' templates. +# And first: Protect against being on the right side of a sed subst in +# config.status. Protect against being in an unquoted here document +# in config.status. +rm -f conftest.defines conftest.undefs +# Using a here document instead of a string reduces the quoting nightmare. +# Putting comments in sed scripts is not portable. +# +# `end' is used to avoid that the second main sed command (meant for +# 0-ary CPP macros) applies to n-ary macro definitions. +# See the Autoconf documentation for `clear'. +cat >confdef2sed.sed <<\_ACEOF +s/[\\&,]/\\&/g +s,[\\$`],\\&,g +t clear +: clear +s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*\)\(([^)]*)\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1\2${ac_dC}\3${ac_dD},gp +t end +s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1${ac_dC}\2${ac_dD},gp +: end +_ACEOF +# If some macros were called several times there might be several times +# the same #defines, which is useless. Nevertheless, we may not want to +# sort them, since we want the *last* AC-DEFINE to be honored. +uniq confdefs.h | sed -n -f confdef2sed.sed >conftest.defines +sed 's/ac_d/ac_u/g' conftest.defines >conftest.undefs +rm -f confdef2sed.sed + +# This sed command replaces #undef with comments. This is necessary, for +# example, in the case of _POSIX_SOURCE, which is predefined and required +# on some systems where configure will not decide to define it. +cat >>conftest.undefs <<\_ACEOF +s,^[ ]*#[ ]*undef[ ][ ]*[a-zA-Z_][a-zA-Z_0-9]*,/* & */, +_ACEOF + +# Break up conftest.defines because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #define templates only if necessary.' >>$CONFIG_STATUS +echo ' if grep "^[ ]*#[ ]*define" $tmp/in >/dev/null; then' >>$CONFIG_STATUS +echo ' # If there are no defines, we may have an empty if/fi' >>$CONFIG_STATUS +echo ' :' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.defines >/dev/null +do + # Write a limited-size here document to $tmp/defines.sed. + echo ' cat >$tmp/defines.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#define' lines. + echo '/^[ ]*#[ ]*define/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.defines >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/defines.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.defines >conftest.tail + rm -f conftest.defines + mv conftest.tail conftest.defines +done +rm -f conftest.defines +echo ' fi # grep' >>$CONFIG_STATUS +echo >>$CONFIG_STATUS + +# Break up conftest.undefs because some shells have a limit on the size +# of here documents, and old seds have small limits too (100 cmds). +echo ' # Handle all the #undef templates' >>$CONFIG_STATUS +rm -f conftest.tail +while grep . conftest.undefs >/dev/null +do + # Write a limited-size here document to $tmp/undefs.sed. + echo ' cat >$tmp/undefs.sed <>$CONFIG_STATUS + # Speed up: don't consider the non `#undef' + echo '/^[ ]*#[ ]*undef/!b' >>$CONFIG_STATUS + # Work around the forget-to-reset-the-flag bug. + echo 't clr' >>$CONFIG_STATUS + echo ': clr' >>$CONFIG_STATUS + sed ${ac_max_here_lines}q conftest.undefs >>$CONFIG_STATUS + echo 'CEOF + sed -f $tmp/undefs.sed $tmp/in >$tmp/out + rm -f $tmp/in + mv $tmp/out $tmp/in +' >>$CONFIG_STATUS + sed 1,${ac_max_here_lines}d conftest.undefs >conftest.tail + rm -f conftest.undefs + mv conftest.tail conftest.undefs +done +rm -f conftest.undefs + +cat >>$CONFIG_STATUS <<\_ACEOF + # Let's still pretend it is `configure' which instantiates (i.e., don't + # use $as_me), people would be surprised to read: + # /* config.h. Generated by config.status. */ + if test x"$ac_file" = x-; then + echo "/* Generated by configure. */" >$tmp/config.h + else + echo "/* $ac_file. Generated by configure. */" >$tmp/config.h + fi + cat $tmp/in >>$tmp/config.h + rm -f $tmp/in + if test x"$ac_file" != x-; then + if diff $ac_file $tmp/config.h >/dev/null 2>&1; then + { echo "$as_me:$LINENO: $ac_file is unchanged" >&5 +echo "$as_me: $ac_file is unchanged" >&6;} + else + ac_dir=`(dirname "$ac_file") 2>/dev/null || +$as_expr X"$ac_file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$ac_file" : 'X\(//\)[^/]' \| \ + X"$ac_file" : 'X\(//\)$' \| \ + X"$ac_file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$ac_file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + rm -f $ac_file + mv $tmp/config.h $ac_file + fi + else + cat $tmp/config.h + rm -f $tmp/config.h + fi +# Compute $ac_file's index in $config_headers. +_am_stamp_count=1 +for _am_header in $config_headers :; do + case $_am_header in + $ac_file | $ac_file:* ) + break ;; + * ) + _am_stamp_count=`expr $_am_stamp_count + 1` ;; + esac +done +echo "timestamp for $ac_file" >`(dirname $ac_file) 2>/dev/null || +$as_expr X$ac_file : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X$ac_file : 'X\(//\)[^/]' \| \ + X$ac_file : 'X\(//\)$' \| \ + X$ac_file : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X$ac_file | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'`/stamp-h$_am_stamp_count +done +_ACEOF +cat >>$CONFIG_STATUS <<\_ACEOF + +# +# CONFIG_COMMANDS section. +# +for ac_file in : $CONFIG_COMMANDS; do test "x$ac_file" = x: && continue + ac_dest=`echo "$ac_file" | sed 's,:.*,,'` + ac_source=`echo "$ac_file" | sed 's,[^:]*:,,'` + ac_dir=`(dirname "$ac_dest") 2>/dev/null || +$as_expr X"$ac_dest" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$ac_dest" : 'X\(//\)[^/]' \| \ + X"$ac_dest" : 'X\(//\)$' \| \ + X"$ac_dest" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$ac_dest" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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We invoke sed twice because it is the + # simplest approach to changing $(DEPDIR) to its actual value in the + # expansion. + for file in `sed -n " + s/^$am__include $am__quote\(.*(DEPDIR).*\)$am__quote"'$/\1/p' <"$mf" | \ + sed -e 's/\$(DEPDIR)/'"$DEPDIR"'/g' -e 's/\$U/'"$U"'/g'`; do + # Make sure the directory exists. + test -f "$dirpart/$file" && continue + fdir=`(dirname "$file") 2>/dev/null || +$as_expr X"$file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$file" : 'X\(//\)[^/]' \| \ + X"$file" : 'X\(//\)$' \| \ + X"$file" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$file" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + { if $as_mkdir_p; then + mkdir -p $dirpart/$fdir + else + as_dir=$dirpart/$fdir + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory $dirpart/$fdir" >&5 +echo "$as_me: error: cannot create directory $dirpart/$fdir" >&2;} + { (exit 1); exit 1; }; }; } + + # echo "creating $dirpart/$file" + echo '# dummy' > "$dirpart/$file" + done +done + ;; + esac +done +_ACEOF + +cat >>$CONFIG_STATUS <<\_ACEOF + +{ (exit 0); exit 0; } +_ACEOF +chmod +x $CONFIG_STATUS +ac_clean_files=$ac_clean_files_save + + +# configure is writing to config.log, and then calls config.status. +# config.status does its own redirection, appending to config.log. +# Unfortunately, on DOS this fails, as config.log is still kept open +# by configure, so config.status won't be able to write to it; its +# output is simply discarded. So we exec the FD to /dev/null, +# effectively closing config.log, so it can be properly (re)opened and +# appended to by config.status. When coming back to configure, we +# need to make the FD available again. +if test "$no_create" != yes; then + ac_cs_success=: + ac_config_status_args= + test "$silent" = yes && + ac_config_status_args="$ac_config_status_args --quiet" + exec 5>/dev/null + $SHELL $CONFIG_STATUS $ac_config_status_args || ac_cs_success=false + exec 5>>config.log + # Use ||, not &&, to avoid exiting from the if with $? = 1, which + # would make configure fail if this is the last instruction. + $ac_cs_success || { (exit 1); exit 1; } +fi + +# +# CONFIG_SUBDIRS section. +# +if test "$no_recursion" != yes; then + + # Remove --cache-file and --srcdir arguments so they do not pile up. + ac_sub_configure_args= + ac_prev= + for ac_arg in $ac_configure_args; do + if test -n "$ac_prev"; then + ac_prev= + continue + fi + case $ac_arg in + -cache-file | --cache-file | --cache-fil | --cache-fi \ + | --cache-f | --cache- | --cache | --cach | --cac | --ca | --c) + ac_prev=cache_file ;; + -cache-file=* | --cache-file=* | --cache-fil=* | --cache-fi=* \ + | --cache-f=* | --cache-=* | --cache=* | --cach=* | --cac=* | --ca=* \ + | --c=*) + ;; + --config-cache | -C) + ;; + -srcdir | --srcdir | --srcdi | --srcd | --src | --sr) + ac_prev=srcdir ;; + -srcdir=* | --srcdir=* | --srcdi=* | --srcd=* | --src=* | --sr=*) + ;; + -prefix | --prefix | --prefi | --pref | --pre | --pr | --p) + ac_prev=prefix ;; + -prefix=* | --prefix=* | --prefi=* | --pref=* | --pre=* | --pr=* | --p=*) + ;; + *) ac_sub_configure_args="$ac_sub_configure_args $ac_arg" ;; + esac + done + + # Always prepend --prefix to ensure using the same prefix + # in subdir configurations. + ac_sub_configure_args="--prefix=$prefix $ac_sub_configure_args" + + ac_popdir=`pwd` + for ac_dir in : $subdirs; do test "x$ac_dir" = x: && continue + + # Do not complain, so a configure script can configure whichever + # parts of a large source tree are present. + test -d $srcdir/$ac_dir || continue + + { echo "$as_me:$LINENO: configuring in $ac_dir" >&5 +echo "$as_me: configuring in $ac_dir" >&6;} + { if $as_mkdir_p; then + mkdir -p "$ac_dir" + else + as_dir="$ac_dir" + as_dirs= + while test ! -d "$as_dir"; do + as_dirs="$as_dir $as_dirs" + as_dir=`(dirname "$as_dir") 2>/dev/null || +$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \ + X"$as_dir" : 'X\(//\)[^/]' \| \ + X"$as_dir" : 'X\(//\)$' \| \ + X"$as_dir" : 'X\(/\)' \| \ + . : '\(.\)' 2>/dev/null || +echo X"$as_dir" | + sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; } + /^X\(\/\/\)[^/].*/{ s//\1/; q; } + /^X\(\/\/\)$/{ s//\1/; q; } + /^X\(\/\).*/{ s//\1/; q; } + s/.*/./; q'` + done + test ! -n "$as_dirs" || mkdir $as_dirs + fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5 +echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;} + { (exit 1); exit 1; }; }; } + + ac_builddir=. + +if test "$ac_dir" != .; then + ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'` + # A "../" for each directory in $ac_dir_suffix. + ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'` +else + ac_dir_suffix= ac_top_builddir= +fi + +case $srcdir in + .) # No --srcdir option. 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$ac_abs_builddir in +.) ac_abs_srcdir=$ac_srcdir;; +*) + case $ac_srcdir in + .) ac_abs_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_srcdir=$ac_srcdir;; + *) ac_abs_srcdir=$ac_abs_builddir/$ac_srcdir;; + esac;; +esac +case $ac_abs_builddir in +.) ac_abs_top_srcdir=$ac_top_srcdir;; +*) + case $ac_top_srcdir in + .) ac_abs_top_srcdir=$ac_abs_builddir;; + [\\/]* | ?:[\\/]* ) ac_abs_top_srcdir=$ac_top_srcdir;; + *) ac_abs_top_srcdir=$ac_abs_builddir/$ac_top_srcdir;; + esac;; +esac + + + cd $ac_dir + + # Check for guested configure; otherwise get Cygnus style configure. + if test -f $ac_srcdir/configure.gnu; then + ac_sub_configure="$SHELL '$ac_srcdir/configure.gnu'" + elif test -f $ac_srcdir/configure; then + ac_sub_configure="$SHELL '$ac_srcdir/configure'" + elif test -f $ac_srcdir/configure.in; then + ac_sub_configure=$ac_configure + else + { echo "$as_me:$LINENO: WARNING: no configuration information is in $ac_dir" >&5 +echo "$as_me: WARNING: no configuration information is in $ac_dir" >&2;} + ac_sub_configure= + fi + + # The recursion is here. + if test -n "$ac_sub_configure"; then + # Make the cache file name correct relative to the subdirectory. + case $cache_file in + [\\/]* | ?:[\\/]* ) ac_sub_cache_file=$cache_file ;; + *) # Relative path. + ac_sub_cache_file=$ac_top_builddir$cache_file ;; + esac + + { echo "$as_me:$LINENO: running $ac_sub_configure $ac_sub_configure_args --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir" >&5 +echo "$as_me: running $ac_sub_configure $ac_sub_configure_args --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir" >&6;} + # The eval makes quoting arguments work. + eval $ac_sub_configure $ac_sub_configure_args \ + --cache-file=$ac_sub_cache_file --srcdir=$ac_srcdir || + { { echo "$as_me:$LINENO: error: $ac_sub_configure failed for $ac_dir" >&5 +echo "$as_me: error: $ac_sub_configure failed for $ac_dir" >&2;} + { (exit 1); exit 1; }; } + fi + + cd $ac_popdir + done +fi + + +eval _bindir=$(eval echo $bindir) +eval _libdir=$(eval echo $libdir) +eval _includedir=${includedir} +eval _datadir=$datadir +eval _mandir=$mandir + +{ echo "$as_me:$LINENO: +Configure successful with the following options: + + Perl Extension: ${with_perl:-yes} + Analyse{Dists,Seqs}: ${with_cluster:-no} + Kinfold: ${with_kinfold:-yes} + RNAforester: ${with_forester:-yes} + +Files will be installed in the following directories: + + Executables: $_bindir + Libraries: $_libdir + Header files: $_includedir + Extra Data: $_datadir + Man pages: $_mandir +" >&5 +echo "$as_me: +Configure successful with the following options: + + Perl Extension: ${with_perl:-yes} + Analyse{Dists,Seqs}: ${with_cluster:-no} + Kinfold: ${with_kinfold:-yes} + RNAforester: ${with_forester:-yes} + +Files will be installed in the following directories: + + Executables: $_bindir + Libraries: $_libdir + Header files: $_includedir + Extra Data: $_datadir + Man pages: $_mandir +" >&6;} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure.in new file mode 100755 index 00000000..0f63161f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/configure.in @@ -0,0 +1,118 @@ +dnl Process this file with autoconf to produce a configure script. +AC_INIT([ViennaRNA],[1.6],[rna@tbi.univie.ac.at],[ViennaRNA]) +dnl Every other copy of the package version number gets its value from here +AM_INIT_AUTOMAKE +dnl change the default installation prefix +dnl AC_PREFIX_DEFAULT(/usr/local/RNA) + +dnl configure options +AM_WITH_DMALLOC +AC_ARG_WITH(cluster, [ --with-cluster build AnalyseSeqs and AnalyseDists]) +AC_ARG_WITH(perl, [ --without-perl don't build Perl module]) +AC_ARG_WITH(forester, [ --without-forester don't build RNAforester program]) +AC_ARG_WITH(kinfold, [ --without-kinfold don't build Kinfold program]) +AC_ARG_ENABLE(floatpf, [ --enable-floatpf use float instead of double for partition function], []) + +dnl create a config.h file (Automake will add -DHAVE_CONFIG_H) +AC_CONFIG_HEADERS([config.h]) + +AC_SUBST(VERSION) + +ISODATE=`date +%Y-%m-%d` +AC_SUBST(ISODATE) + +AC_CANONICAL_HOST + +dnl Checks for programs. +AC_PROG_CC +if test "$GCC" = yes; then + AC_DEFINE(UNUSED, __attribute__ ((unused)), avoid warning about unused variables) +else + AC_DEFINE(UNUSED,, only for gcc) +fi +AC_PROG_INSTALL +AC_PROG_RANLIB + +AC_PATH_PROG(PerlCmd, perl) +if test -n "$PerlCmd"; then + if $PerlCmd -e 'require 5.004'; then : + else + AC_MSG_RESULT(You need Perl version 5.004 or higher for the Perl module) + with_perl="no" + fi +fi + +if test -z "$PerlCmd"; then + AC_MSG_RESULT(No suitable Perl found -- will not build Perl module) + AC_MSG_RESULT(You may set the PerlCmd environment variable to point to + a suitable perl binary) + with_perl="no" +fi + +if test "$with_forester" != "no"; then + if test -f $srcdir/RNAforester/Makefile.am; then + AC_CONFIG_SUBDIRS(RNAforester) + else + AC_MSG_WARN([RNAforester subdirectory does not exist]) + with_forester="no" + fi +fi + +if test "$with_kinfold" != "no"; then + if test -f $srcdir/Kinfold/Makefile.am; then + AC_CONFIG_SUBDIRS(Kinfold) + else + AC_MSG_WARN([Kinfold subdirectory does not exist]) + with_kinfold="no" + fi +fi + +AM_CONDITIONAL(MAKE_PERL_EXT, test "$with_perl" != "no") + +AM_CONDITIONAL(MAKE_CLUSTER, test "$with_cluster" = "yes") + +AM_CONDITIONAL(MAKE_FORESTER, test "$with_forester" != "no") + +AM_CONDITIONAL(MAKE_KINFOLD, test "$with_kinfold" != "no") + +dnl Checks for libraries. +dnl AC_REPLACE_GNU_GETOPT + +dnl Checks for header files. +AC_HEADER_STDC +AC_CHECK_HEADERS(malloc.h strings.h unistd.h) + +dnl Checks for typedefs, structures, and compiler characteristics. +AC_C_CONST +AC_TYPE_SIZE_T +AC_C_INLINE([]) + +dnl Checks for library functions. +AC_CHECK_FUNCS(strdup strstr strchr erand48) + +AC_CONFIG_FILES([Makefile ViennaRNA.spec Utils/Makefile Progs/Makefile lib/Makefile man/Makefile Cluster/Makefile H/Makefile Perl/Makefile man/RNAheat.1 man/RNAsubopt.1 man/RNAdistance.1 man/RNAinverse.1 man/RNAeval.1 man/RNAfold.1 man/RNApdist.1 man/RNAplot.1 man/RNALfold.1 man/RNAalifold.1 man/RNAduplex.1 man/RNAcofold.1 man/RNAplfold.1]) +AC_OUTPUT + +eval _bindir=$(eval echo $bindir) +eval _libdir=$(eval echo $libdir) +eval _includedir=${includedir} +eval _datadir=$datadir +eval _mandir=$mandir + +AC_MSG_NOTICE( +[ +Configure successful with the following options: + + Perl Extension: ${with_perl:-yes} + Analyse{Dists,Seqs}: ${with_cluster:-no} + Kinfold: ${with_kinfold:-yes} + RNAforester: ${with_forester:-yes} + +Files will be installed in the following directories: + + Executables: $_bindir + Libraries: $_libdir + Header files: $_includedir + Extra Data: $_datadir + Man pages: $_mandir +]) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/default.par b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/default.par new file mode 100755 index 00000000..442aca4f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/default.par @@ -0,0 +1,11620 @@ +## RNAfold parameter file + +# stack_energies +/* CG GC GU UG AU UA @ */ + -240 -330 -210 -140 -210 -210 NST + -330 -340 -250 -150 -220 -240 NST + -210 -250 130 -50 -140 -130 NST + -140 -150 -50 30 -60 -100 NST + -210 -220 -140 -60 -110 -90 NST + -210 -240 -130 -100 -90 -130 NST + NST NST NST NST NST NST NST + +# stack_enthalpies +/* CG GC GU UG AU UA @ */ + -1060 -1340 -1210 -560 -1050 -1040 0 + -1340 -1490 -1260 -830 -1140 -1240 0 + -1210 -1260 -1460 -1350 -880 -1280 0 + -560 -830 -1350 -930 -320 -700 0 + -1050 -1140 -880 -320 -940 -680 0 + -1040 -1240 -1280 -700 -680 -770 0 + 0 0 0 0 0 0 0 + +# mismatch_hairpin + 0 0 0 0 0 + -90 -150 -150 -140 -180 + -90 -100 -90 -290 -80 + -90 -220 -200 -160 -110 + -90 -170 -140 -180 -200 + 0 0 0 0 0 + -70 -110 -150 -130 -210 + -70 -110 -70 -240 -50 + -70 -240 -290 -140 -120 + -70 -190 -100 -220 -150 + 0 0 0 0 0 + 0 20 -50 -30 -30 + 0 -10 -20 -150 -20 + 0 -90 -110 -30 0 + 0 -30 -30 -40 -110 + 0 0 0 0 0 + 0 -50 -30 -60 -50 + 0 -20 -10 -170 0 + 0 -80 -120 -30 -70 + 0 -60 -10 -60 -80 + 0 0 0 0 0 + 0 -30 -50 -30 -30 + 0 -10 -20 -150 -20 + 0 -110 -120 -20 20 + 0 -30 -30 -60 -110 + 0 0 0 0 0 + 0 -50 -30 -60 -50 + 0 -20 -10 -120 0 + 0 -140 -120 -70 -20 + 0 -30 -10 -50 -80 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + +# mismatch_interior + 0 0 0 0 0 + 0 0 0 -110 0 + 0 0 0 0 0 + 0 -110 0 0 0 + 0 0 0 0 -70 + 0 0 0 0 0 + 0 0 0 -110 0 + 0 0 0 0 0 + 0 -110 0 0 0 + 0 0 0 0 -70 + 0 0 0 0 0 + 0 70 70 -40 70 + 0 70 70 70 70 + 0 -40 70 70 70 + 0 70 70 70 0 + 0 0 0 0 0 + 0 70 70 -40 70 + 0 70 70 70 70 + 0 -40 70 70 70 + 0 70 70 70 0 + 0 0 0 0 0 + 0 70 70 -40 70 + 0 70 70 70 70 + 0 -40 70 70 70 + 0 70 70 70 0 + 0 0 0 0 0 + 0 70 70 -40 70 + 0 70 70 70 70 + 0 -40 70 70 70 + 0 70 70 70 0 + 90 90 90 90 90 + 90 90 90 90 -20 + 90 90 90 90 90 + 90 -20 90 90 90 + 90 90 90 90 20 + +# mismatch_enthalpies + 0 0 0 0 0 + DEF -1030 -950 -1030 -1030 + DEF -520 -450 -520 -670 + DEF -940 -940 -940 -940 + DEF -810 -740 -810 -860 + 0 0 0 0 0 + DEF -520 -880 -560 -880 + DEF -720 -310 -310 -390 + DEF -710 -740 -620 -740 + DEF -500 -500 -500 -570 + 0 0 0 0 0 + DEF -430 -600 -600 -600 + DEF -260 -240 -240 -240 + DEF -340 -690 -690 -690 + DEF -330 -330 -330 -330 + 0 0 0 0 0 + DEF -720 -790 -960 -810 + DEF -480 -480 -360 -480 + DEF -660 -810 -920 -810 + DEF -550 -440 -550 -360 + 0 0 0 0 0 + DEF -430 -600 -600 -600 + DEF -260 -240 -240 -240 + DEF -340 -690 -690 -690 + DEF -330 -330 -330 -330 + 0 0 0 0 0 + DEF -400 -630 -890 -590 + DEF -430 -510 -200 -180 + DEF -380 -680 -890 -680 + DEF -280 -140 -280 -140 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + +# dangle5 +/* @ A C G U */ + INF INF INF INF INF + INF -50 -30 -20 -10 + INF -20 -30 0 0 + INF -30 -30 -40 -20 + INF -30 -10 -20 -20 + INF -30 -30 -40 -20 + INF -30 -10 -20 -20 + 0 0 0 0 0 + +# dangle3 +/* @ A C G U */ + INF INF INF INF INF + INF -110 -40 -130 -60 + INF -170 -80 -170 -120 + INF -70 -10 -70 -10 + INF -80 -50 -80 -60 + INF -70 -10 -70 -10 + INF -80 -50 -80 -60 + 0 0 0 0 0 + +# dangle5_enthalpies +/* @ A C G U */ + INF INF INF INF INF + 0 -240 330 80 -140 + 0 -160 70 -460 -40 + 0 160 220 70 310 + 0 -150 510 10 100 + 0 160 220 70 310 + 0 -50 690 -60 -60 + 0 0 0 0 0 + +# dangle3_enthalpies +/* @ A C G U */ + INF INF INF INF INF + 0 -740 -280 -640 -360 + 0 -900 -410 -860 -750 + 0 -740 -240 -720 -490 + 0 -490 -90 -550 -230 + 0 -570 -70 -580 -220 + 0 -490 -90 -550 -230 + 0 0 0 0 0 + +# int11_energies +/* GC..GC */ + 110 110 110 110 110 + 110 110 40 40 40 + 110 40 40 40 40 + 110 40 40 -140 40 + 110 40 40 40 40 +/* GC..CG */ + 110 110 110 110 110 + 110 40 -40 40 40 + 110 30 50 40 50 + 110 -10 40 -170 40 + 110 40 0 40 -30 +/* GC..GU */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GC..UG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GC..AU */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GC..UA */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GC.. @ */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 +/* CG..GC */ + 110 110 110 110 110 + 110 40 30 -10 40 + 110 -40 50 40 0 + 110 40 40 -170 40 + 110 40 50 40 -30 +/* CG..CG */ + 110 110 110 110 110 + 110 80 40 40 40 + 110 40 40 40 40 + 110 40 40 -210 40 + 110 40 40 40 -70 +/* CG..GU */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* CG..UG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* CG..AU */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 100 +/* CG..UA */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* CG.. @ */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 +/* GU..GC */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GU..CG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* GU..GU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* GU..UG */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* GU..AU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* GU..UA */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* GU.. @ */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* UG..GC */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* UG..CG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* UG..GU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UG..UG */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UG..AU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UG..UA */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UG.. @ */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* AU..GC */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* AU..CG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 100 +/* AU..GU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* AU..UG */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* AU..AU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 120 +/* AU..UA */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 150 +/* AU.. @ */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* UA..GC */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* UA..CG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 -100 110 + 110 110 110 110 110 +/* UA..GU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UA..UG */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 170 +/* UA..AU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 150 +/* UA..UA */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 -40 170 + 170 170 170 170 180 +/* UA.. @ */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* @..GC */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 +/* @..CG */ + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 + 110 110 110 110 110 +/* @..GU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* @..UG */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* @..AU */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* @..UA */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 +/* @.. @ */ + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + 170 170 170 170 170 + +# int11_enthalpies +/* GC..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GC.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* CG.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* GU.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UG.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* AU.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* UA.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..GC */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..CG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..GU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..UG */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..AU */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @..UA */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 +/* @.. @ */ + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + +# int21_energies +/* GC.@..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* GC.A..GC */ + 550 550 550 550 550 + 550 240 220 160 400 + 550 210 170 160 400 + 550 100 60 40 400 + 550 400 400 400 400 +/* GC.C..GC */ + 550 550 550 550 550 + 550 230 220 400 220 + 550 220 250 400 220 + 550 400 400 400 400 + 550 250 190 400 220 +/* GC.G..GC */ + 550 550 550 550 550 + 550 170 400 80 400 + 550 400 400 400 400 + 550 80 400 220 400 + 550 400 400 400 400 +/* GC.U..GC */ + 550 550 550 550 550 + 550 400 400 400 400 + 550 400 220 400 130 + 550 400 400 400 400 + 550 400 170 400 120 +/* GC.@..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* GC.A..CG */ + 550 550 550 550 550 + 550 230 220 110 400 + 550 210 170 160 400 + 550 80 60 40 400 + 550 400 400 400 400 +/* GC.C..CG */ + 550 550 550 550 550 + 550 230 220 400 220 + 550 220 250 400 220 + 550 400 400 400 400 + 550 250 190 400 220 +/* GC.G..CG */ + 550 550 550 550 550 + 550 170 400 80 400 + 550 400 400 400 400 + 550 80 400 220 400 + 550 400 400 400 400 +/* GC.U..CG */ + 550 550 550 550 550 + 550 400 400 400 400 + 550 400 220 400 150 + 550 400 400 400 400 + 550 400 170 400 120 +/* GC.@..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* GC.A..GU */ + 550 550 550 550 550 + 550 320 300 240 480 + 550 290 250 240 480 + 550 180 140 120 480 + 550 480 480 480 480 +/* GC.C..GU */ + 550 550 550 550 550 + 550 310 300 480 300 + 550 300 330 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UA.@..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..AU */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..AU */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..AU */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A..UA */ + 550 550 550 550 550 + 550 390 370 310 550 + 550 360 320 310 550 + 550 250 210 190 550 + 550 550 550 550 550 +/* UA.C..UA */ + 550 550 550 550 550 + 550 380 370 550 370 + 550 370 400 550 370 + 550 550 550 550 550 + 550 400 340 550 370 +/* UA.G..UA */ + 550 550 550 550 550 + 550 320 550 230 550 + 550 550 550 550 550 + 550 230 550 370 550 + 550 550 550 550 550 +/* UA.U..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 370 550 280 + 550 550 550 550 550 + 550 550 320 550 270 +/* UA.@.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.A.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.C.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.G.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* UA.U.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..GC */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..CG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..GU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..UG */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..AU */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U..UA */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.@.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.A.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.C.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.G.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 +/* @.U.. @ */ + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + 550 550 550 550 550 + +# int21_enthalpies +/* CG.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..CG */ + DEF -1029 -949 -1029 -1029 + -1079 -2058 -1978 -2058 -2058 + -569 -1548 -1468 -1548 -1548 + -989 -1968 -1888 -1968 -1968 + -859 -1838 -1758 -1838 -1838 +/* CG.C..CG */ + DEF -519 -449 -519 -669 + -999 -1468 -1398 -1468 -1618 + -499 -968 -898 -968 -1118 + -989 -1458 -1388 -1458 -1608 + -789 -1258 -1188 -1258 -1408 +/* CG.G..CG */ + DEF -939 -939 -939 -939 + -1079 -1968 -1968 -1968 -1968 + -569 -1458 -1458 -1458 -1458 + -989 -1878 -1878 -1878 -1878 + -859 -1748 -1748 -1748 -1748 +/* CG.U..CG */ + DEF -809 -739 -809 -859 + -1079 -1838 -1768 -1838 -1888 + -719 -1478 -1408 -1478 -1528 + -989 -1748 -1678 -1748 -1798 + -909 -1668 -1598 -1668 -1718 +/* CG.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..GC */ + DEF -1029 -949 -1029 -1029 + -569 -1548 -1468 -1548 -1548 + -769 -1748 -1668 -1748 -1748 + -759 -1738 -1658 -1738 -1738 + -549 -1528 -1448 -1528 -1528 +/* CG.C..GC */ + DEF -519 -449 -519 -669 + -929 -1398 -1328 -1398 -1548 + -359 -828 -758 -828 -978 + -789 -1258 -1188 -1258 -1408 + -549 -1018 -948 -1018 -1168 +/* CG.G..GC */ + DEF -939 -939 -939 -939 + -609 -1498 -1498 -1498 -1498 + -359 -1248 -1248 -1248 -1248 + -669 -1558 -1558 -1558 -1558 + -549 -1438 -1438 -1438 -1438 +/* CG.U..GC */ + DEF -809 -739 -809 -859 + -929 -1688 -1618 -1688 -1738 + -439 -1198 -1128 -1198 -1248 + -789 -1548 -1478 -1548 -1598 + -619 -1378 -1308 -1378 -1428 +/* CG.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..GU */ + DEF -1029 -949 -1029 -1029 + -479 -1458 -1378 -1458 -1458 + -309 -1288 -1208 -1288 -1288 + -389 -1368 -1288 -1368 -1368 + -379 -1358 -1278 -1358 -1358 +/* CG.C..GU */ + DEF -519 -449 -519 -669 + -649 -1118 -1048 -1118 -1268 + -289 -758 -688 -758 -908 + -739 -1208 -1138 -1208 -1358 + -379 -848 -778 -848 -998 +/* CG.G..GU */ + DEF -939 -939 -939 -939 + -649 -1538 -1538 -1538 -1538 + -289 -1178 -1178 -1178 -1178 + -739 -1628 -1628 -1628 -1628 + -379 -1268 -1268 -1268 -1268 +/* CG.U..GU */ + DEF -809 -739 -809 -859 + -649 -1408 -1338 -1408 -1458 + -289 -1048 -978 -1048 -1098 + -739 -1498 -1428 -1498 -1548 + -379 -1138 -1068 -1138 -1188 +/* CG.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..UG */ + DEF -1029 -949 -1029 -1029 + -769 -1748 -1668 -1748 -1748 + -529 -1508 -1428 -1508 -1508 + -709 -1688 -1608 -1688 -1688 + -599 -1578 -1498 -1578 -1578 +/* CG.C..UG */ + DEF -519 -449 -519 -669 + -839 -1308 -1238 -1308 -1458 + -529 -998 -928 -998 -1148 + -859 -1328 -1258 -1328 -1478 + -489 -958 -888 -958 -1108 +/* CG.G..UG */ + DEF -939 -939 -939 -939 + -1009 -1898 -1898 -1898 -1898 + -409 -1298 -1298 -1298 -1298 + -969 -1858 -1858 -1858 -1858 + -599 -1488 -1488 -1488 -1488 +/* CG.U..UG */ + DEF -809 -739 -809 -859 + -859 -1618 -1548 -1618 -1668 + -529 -1288 -1218 -1288 -1338 + -859 -1618 -1548 -1618 -1668 + -409 -1168 -1098 -1168 -1218 +/* CG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..AU */ + DEF -1029 -949 -1029 -1029 + -479 -1458 -1378 -1458 -1458 + -309 -1288 -1208 -1288 -1288 + -389 -1368 -1288 -1368 -1368 + -379 -1358 -1278 -1358 -1358 +/* CG.C..AU */ + DEF -519 -449 -519 -669 + -649 -1118 -1048 -1118 -1268 + -289 -758 -688 -758 -908 + -739 -1208 -1138 -1208 -1358 + -379 -848 -778 -848 -998 +/* CG.G..AU */ + DEF -939 -939 -939 -939 + -649 -1538 -1538 -1538 -1538 + -289 -1178 -1178 -1178 -1178 + -739 -1628 -1628 -1628 -1628 + -379 -1268 -1268 -1268 -1268 +/* CG.U..AU */ + DEF -809 -739 -809 -859 + -649 -1408 -1338 -1408 -1458 + -289 -1048 -978 -1048 -1098 + -739 -1498 -1428 -1498 -1548 + -379 -1138 -1068 -1138 -1188 +/* CG.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..UA */ + DEF -1029 -949 -1029 -1029 + -449 -1428 -1348 -1428 -1428 + -479 -1458 -1378 -1458 -1458 + -429 -1408 -1328 -1408 -1408 + -329 -1308 -1228 -1308 -1308 +/* CG.C..UA */ + DEF -519 -449 -519 -669 + -679 -1148 -1078 -1148 -1298 + -559 -1028 -958 -1028 -1178 + -729 -1198 -1128 -1198 -1348 + -189 -658 -588 -658 -808 +/* CG.G..UA */ + DEF -939 -939 -939 -939 + -939 -1828 -1828 -1828 -1828 + -249 -1138 -1138 -1138 -1138 + -939 -1828 -1828 -1828 -1828 + -329 -1218 -1218 -1218 -1218 +/* CG.U..UA */ + DEF -809 -739 -809 -859 + -639 -1398 -1328 -1398 -1448 + -229 -988 -918 -988 -1038 + -729 -1488 -1418 -1488 -1538 + -190 -949 -879 -949 -999 +/* CG.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A.. @ */ + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 + -100 -1079 -999 -1079 -1079 +/* CG.C.. @ */ + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 + -100 -569 -499 -569 -719 +/* CG.G.. @ */ + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 + -100 -989 -989 -989 -989 +/* CG.U.. @ */ + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 + -100 -859 -789 -859 -909 +/* GC.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..CG */ + DEF -519 -879 -559 -879 + -1079 -1548 -1908 -1588 -1908 + -569 -1038 -1398 -1078 -1398 + -989 -1458 -1818 -1498 -1818 + -859 -1328 -1688 -1368 -1688 +/* GC.C..CG */ + DEF -719 -309 -309 -389 + -999 -1668 -1258 -1258 -1338 + -499 -1168 -758 -758 -838 + -989 -1658 -1248 -1248 -1328 + -789 -1458 -1048 -1048 -1128 +/* GC.G..CG */ + DEF -709 -739 -619 -739 + -1079 -1738 -1768 -1648 -1768 + -569 -1228 -1258 -1138 -1258 + -989 -1648 -1678 -1558 -1678 + -859 -1518 -1548 -1428 -1548 +/* GC.U..CG */ + DEF -499 -499 -499 -569 + -1079 -1528 -1528 -1528 -1598 + -719 -1168 -1168 -1168 -1238 + -989 -1438 -1438 -1438 -1508 + -909 -1358 -1358 -1358 -1428 +/* GC.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..GC */ + DEF -519 -879 -559 -879 + -569 -1038 -1398 -1078 -1398 + -769 -1238 -1598 -1278 -1598 + -759 -1228 -1588 -1268 -1588 + -549 -1018 -1378 -1058 -1378 +/* GC.C..GC */ + DEF -719 -309 -309 -389 + -929 -1598 -1188 -1188 -1268 + -359 -1028 -618 -618 -698 + -789 -1458 -1048 -1048 -1128 + -549 -1218 -808 -808 -888 +/* GC.G..GC */ + DEF -709 -739 -619 -739 + -609 -1268 -1298 -1178 -1298 + -359 -1018 -1048 -928 -1048 + -669 -1328 -1358 -1238 -1358 + -549 -1208 -1238 -1118 -1238 +/* GC.U..GC */ + DEF -499 -499 -499 -569 + -929 -1378 -1378 -1378 -1448 + -439 -888 -888 -888 -958 + -789 -1238 -1238 -1238 -1308 + -619 -1068 -1068 -1068 -1138 +/* GC.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..GU */ + DEF -519 -879 -559 -879 + -479 -948 -1308 -988 -1308 + -309 -778 -1138 -818 -1138 + -389 -858 -1218 -898 -1218 + -379 -848 -1208 -888 -1208 +/* GC.C..GU */ + DEF -719 -309 -309 -389 + -649 -1318 -908 -908 -988 + -289 -958 -548 -548 -628 + -739 -1408 -998 -998 -1078 + -379 -1048 -638 -638 -718 +/* GC.G..GU */ + DEF -709 -739 -619 -739 + -649 -1308 -1338 -1218 -1338 + -289 -948 -978 -858 -978 + -739 -1398 -1428 -1308 -1428 + -379 -1038 -1068 -948 -1068 +/* GC.U..GU */ + DEF -499 -499 -499 -569 + -649 -1098 -1098 -1098 -1168 + -289 -738 -738 -738 -808 + -739 -1188 -1188 -1188 -1258 + -379 -828 -828 -828 -898 +/* GC.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..UG */ + DEF -519 -879 -559 -879 + -769 -1238 -1598 -1278 -1598 + -529 -998 -1358 -1038 -1358 + -709 -1178 -1538 -1218 -1538 + -599 -1068 -1428 -1108 -1428 +/* GC.C..UG */ + DEF -719 -309 -309 -389 + -839 -1508 -1098 -1098 -1178 + -529 -1198 -788 -788 -868 + -859 -1528 -1118 -1118 -1198 + -489 -1158 -748 -748 -828 +/* GC.G..UG */ + DEF -709 -739 -619 -739 + -1009 -1668 -1698 -1578 -1698 + -409 -1068 -1098 -978 -1098 + -969 -1628 -1658 -1538 -1658 + -599 -1258 -1288 -1168 -1288 +/* GC.U..UG */ + DEF -499 -499 -499 -569 + -859 -1308 -1308 -1308 -1378 + -529 -978 -978 -978 -1048 + -859 -1308 -1308 -1308 -1378 + -409 -858 -858 -858 -928 +/* GC.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..AU */ + DEF -519 -879 -559 -879 + -479 -948 -1308 -988 -1308 + -309 -778 -1138 -818 -1138 + -389 -858 -1218 -898 -1218 + -379 -848 -1208 -888 -1208 +/* GC.C..AU */ + DEF -719 -309 -309 -389 + -649 -1318 -908 -908 -988 + -289 -958 -548 -548 -628 + -739 -1408 -998 -998 -1078 + -379 -1048 -638 -638 -718 +/* GC.G..AU */ + DEF -709 -739 -619 -739 + -649 -1308 -1338 -1218 -1338 + -289 -948 -978 -858 -978 + -739 -1398 -1428 -1308 -1428 + -379 -1038 -1068 -948 -1068 +/* GC.U..AU */ + DEF -499 -499 -499 -569 + -649 -1098 -1098 -1098 -1168 + -289 -738 -738 -738 -808 + -739 -1188 -1188 -1188 -1258 + -379 -828 -828 -828 -898 +/* GC.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..UA */ + DEF -519 -879 -559 -879 + -449 -918 -1278 -958 -1278 + -479 -948 -1308 -988 -1308 + -429 -898 -1258 -938 -1258 + -329 -798 -1158 -838 -1158 +/* GC.C..UA */ + DEF -719 -309 -309 -389 + -679 -1348 -938 -938 -1018 + -559 -1228 -818 -818 -898 + -729 -1398 -988 -988 -1068 + -189 -858 -448 -448 -528 +/* GC.G..UA */ + DEF -709 -739 -619 -739 + -939 -1598 -1628 -1508 -1628 + -249 -908 -938 -818 -938 + -939 -1598 -1628 -1508 -1628 + -329 -988 -1018 -898 -1018 +/* GC.U..UA */ + DEF -499 -499 -499 -569 + -639 -1088 -1088 -1088 -1158 + -229 -678 -678 -678 -748 + -729 -1178 -1178 -1178 -1248 + -190 -639 -639 -639 -709 +/* GC.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A.. @ */ + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 + -100 -569 -929 -609 -929 +/* GC.C.. @ */ + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 + -100 -769 -359 -359 -439 +/* GC.G.. @ */ + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 +/* GC.U.. @ */ + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 +/* GU.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..CG */ + DEF -429 -599 -599 -599 + -1079 -1458 -1628 -1628 -1628 + -569 -948 -1118 -1118 -1118 + -989 -1368 -1538 -1538 -1538 + -859 -1238 -1408 -1408 -1408 +/* GU.C..CG */ + DEF -259 -239 -239 -239 + -999 -1208 -1188 -1188 -1188 + -499 -708 -688 -688 -688 + -989 -1198 -1178 -1178 -1178 + -789 -998 -978 -978 -978 +/* GU.G..CG */ + DEF -339 -689 -689 -689 + -1079 -1368 -1718 -1718 -1718 + -569 -858 -1208 -1208 -1208 + -989 -1278 -1628 -1628 -1628 + -859 -1148 -1498 -1498 -1498 +/* GU.U..CG */ + DEF -329 -329 -329 -329 + -1079 -1358 -1358 -1358 -1358 + -719 -998 -998 -998 -998 + -989 -1268 -1268 -1268 -1268 + -909 -1188 -1188 -1188 -1188 +/* GU.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GC */ + DEF -429 -599 -599 -599 + -569 -948 -1118 -1118 -1118 + -769 -1148 -1318 -1318 -1318 + -759 -1138 -1308 -1308 -1308 + -549 -928 -1098 -1098 -1098 +/* GU.C..GC */ + DEF -259 -239 -239 -239 + -929 -1138 -1118 -1118 -1118 + -359 -568 -548 -548 -548 + -789 -998 -978 -978 -978 + -549 -758 -738 -738 -738 +/* GU.G..GC */ + DEF -339 -689 -689 -689 + -609 -898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* GU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* GU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* GU.C..GU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* GU.G..GU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 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GU.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..AU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* GU.C..AU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* GU.G..AU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* GU.U..AU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* GU.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..UA */ + DEF -429 -599 -599 -599 + -449 -828 -998 -998 -998 + -479 -858 -1028 -1028 -1028 + -429 -808 -978 -978 -978 + -329 -708 -878 -878 -878 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-1118 -1288 -1138 +/* UG.C..GU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..GU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..GU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UG */ + DEF -719 -789 -959 -809 + -769 -1438 -1508 -1678 -1528 + -529 -1198 -1268 -1438 -1288 + -709 -1378 -1448 -1618 -1468 + -599 -1268 -1338 -1508 -1358 +/* UG.C..UG */ + DEF -479 -479 -359 -479 + -839 -1268 -1268 -1148 -1268 + -529 -958 -958 -838 -958 + -859 -1288 -1288 -1168 -1288 + -489 -918 -918 -798 -918 +/* UG.G..UG */ + DEF -659 -809 -919 -809 + -1009 -1618 -1768 -1878 -1768 + -409 -1018 -1168 -1278 -1168 + -969 -1578 -1728 -1838 -1728 + -599 -1208 -1358 -1468 -1358 +/* UG.U..UG */ + DEF -549 -439 -549 -359 + -859 -1358 -1248 -1358 -1168 + -529 -1028 -918 -1028 -838 + -859 -1358 -1248 -1358 -1168 + -409 -908 -798 -908 -718 +/* UG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..AU */ + DEF -719 -789 -959 -809 + -479 -1148 -1218 -1388 -1238 + -309 -978 -1048 -1218 -1068 + -389 -1058 -1128 -1298 -1148 + -379 -1048 -1118 -1288 -1138 +/* UG.C..AU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..AU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..AU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UA */ + DEF -719 -789 -959 -809 + -449 -1118 -1188 -1358 -1208 + -479 -1148 -1218 -1388 -1238 + -429 -1098 -1168 -1338 -1188 + -329 -998 -1068 -1238 -1088 +/* UG.C..UA */ + DEF -479 -479 -359 -479 + -679 -1108 -1108 -988 -1108 + -559 -988 -988 -868 -988 + -729 -1158 -1158 -1038 -1158 + -189 -618 -618 -498 -618 +/* UG.G..UA */ + DEF -659 -809 -919 -809 + -939 -1548 -1698 -1808 -1698 + -249 -858 -1008 -1118 -1008 + -939 -1548 -1698 -1808 -1698 + -329 -938 -1088 -1198 -1088 +/* UG.U..UA */ + DEF -549 -439 -549 -359 + -639 -1138 -1028 -1138 -948 + -229 -728 -618 -728 -538 + -729 -1228 -1118 -1228 -1038 + -190 -689 -579 -689 -499 +/* UG.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A.. @ */ + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 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-689 + -1079 -1368 -1718 -1718 -1718 + -569 -858 -1208 -1208 -1208 + -989 -1278 -1628 -1628 -1628 + -859 -1148 -1498 -1498 -1498 +/* AU.U..CG */ + DEF -329 -329 -329 -329 + -1079 -1358 -1358 -1358 -1358 + -719 -998 -998 -998 -998 + -989 -1268 -1268 -1268 -1268 + -909 -1188 -1188 -1188 -1188 +/* AU.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..GC */ + DEF -429 -599 -599 -599 + -569 -948 -1118 -1118 -1118 + -769 -1148 -1318 -1318 -1318 + -759 -1138 -1308 -1308 -1308 + -549 -928 -1098 -1098 -1098 +/* AU.C..GC */ + DEF -259 -239 -239 -239 + -929 -1138 -1118 -1118 -1118 + -359 -568 -548 -548 -548 + -789 -998 -978 -978 -978 + -549 -758 -738 -738 -738 +/* AU.G..GC */ + DEF -339 -689 -689 -689 + -609 -898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* AU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* AU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* AU.C..GU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* AU.G..GU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* AU.U..GU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* AU.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..UG */ + DEF -429 -599 -599 -599 + -769 -1148 -1318 -1318 -1318 + -529 -908 -1078 -1078 -1078 + -709 -1088 -1258 -1258 -1258 + -599 -978 -1148 -1148 -1148 +/* AU.C..UG */ + DEF -259 -239 -239 -239 + -839 -1048 -1028 -1028 -1028 + -529 -738 -718 -718 -718 + -859 -1068 -1048 -1048 -1048 + -489 -698 -678 -678 -678 +/* AU.G..UG */ + DEF -339 -689 -689 -689 + -1009 -1298 -1648 -1648 -1648 + -409 -698 -1048 -1048 -1048 + -969 -1258 -1608 -1608 -1608 + -599 -888 -1238 -1238 -1238 +/* AU.U..UG */ + DEF -329 -329 -329 -329 + -859 -1138 -1138 -1138 -1138 + -529 -808 -808 -808 -808 + -859 -1138 -1138 -1138 -1138 + -409 -688 -688 -688 -688 +/* AU.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..AU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* AU.C..AU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* AU.G..AU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* AU.U..AU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* AU.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..UA */ + DEF -429 -599 -599 -599 + -449 -828 -998 -998 -998 + -479 -858 -1028 -1028 -1028 + -429 -808 -978 -978 -978 + -329 -708 -878 -878 -878 +/* AU.C..UA */ + DEF -259 -239 -239 -239 + -679 -888 -868 -868 -868 + -559 -768 -748 -748 -748 + -729 -938 -918 -918 -918 + -189 -398 -378 -378 -378 +/* AU.G..UA */ + DEF -339 -689 -689 -689 + -939 -1228 -1578 -1578 -1578 + -249 -538 -888 -888 -888 + -939 -1228 -1578 -1578 -1578 + -329 -618 -968 -968 -968 +/* AU.U..UA */ + DEF -329 -329 -329 -329 + -639 -918 -918 -918 -918 + -229 -508 -508 -508 -508 + -729 -1008 -1008 -1008 -1008 + -190 -469 -469 -469 -469 +/* AU.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A.. @ */ + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 + -100 -479 -649 -649 -649 +/* AU.C.. @ */ + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 +/* AU.G.. @ */ + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 +/* AU.U.. @ */ + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 +/* UA.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..CG */ + DEF -399 -629 -889 -589 + -1079 -1428 -1658 -1918 -1618 + -569 -918 -1148 -1408 -1108 + -989 -1338 -1568 -1828 -1528 + -859 -1208 -1438 -1698 -1398 +/* UA.C..CG */ + DEF -429 -509 -199 -179 + -999 -1378 -1458 -1148 -1128 + -499 -878 -958 -648 -628 + -989 -1368 -1448 -1138 -1118 + -789 -1168 -1248 -938 -918 +/* UA.G..CG */ + DEF -379 -679 -889 -679 + -1079 -1408 -1708 -1918 -1708 + -569 -898 -1198 -1408 -1198 + -989 -1318 -1618 -1828 -1618 + -859 -1188 -1488 -1698 -1488 +/* UA.U..CG */ + DEF -279 -139 -279 -140 + -1079 -1308 -1168 -1308 -1169 + -719 -948 -808 -948 -809 + -989 -1218 -1078 -1218 -1079 + -909 -1138 -998 -1138 -999 +/* UA.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GC */ + DEF -399 -629 -889 -589 + -569 -918 -1148 -1408 -1108 + -769 -1118 -1348 -1608 -1308 + -759 -1108 -1338 -1598 -1298 + -549 -898 -1128 -1388 -1088 +/* UA.C..GC */ + DEF -429 -509 -199 -179 + -929 -1308 -1388 -1078 -1058 + -359 -738 -818 -508 -488 + -789 -1168 -1248 -938 -918 + -549 -928 -1008 -698 -678 +/* UA.G..GC */ + DEF -379 -679 -889 -679 + -609 -938 -1238 -1448 -1238 + -359 -688 -988 -1198 -988 + -669 -998 -1298 -1508 -1298 + -549 -878 -1178 -1388 -1178 +/* UA.U..GC */ + DEF -279 -139 -279 -140 + -929 -1158 -1018 -1158 -1019 + -439 -668 -528 -668 -529 + -789 -1018 -878 -1018 -879 + -619 -848 -708 -848 -709 +/* UA.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GU */ + DEF -399 -629 -889 -589 + -479 -828 -1058 -1318 -1018 + -309 -658 -888 -1148 -848 + -389 -738 -968 -1228 -928 + -379 -728 -958 -1218 -918 +/* UA.C..GU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..GU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..GU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 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-379 -728 -958 -1218 -918 +/* UA.C..AU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..AU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..AU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 +/* UA.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..UA */ + DEF -399 -629 -889 -589 + -449 -798 -1028 -1288 -988 + -479 -828 -1058 -1318 -1018 + -429 -778 -1008 -1268 -968 + -329 -678 -908 -1168 -868 +/* UA.C..UA */ + DEF -429 -509 -199 -179 + -679 -1058 -1138 -828 -808 + -559 -938 -1018 -708 -688 + -729 -1108 -1188 -878 -858 + -189 -568 -648 -338 -318 +/* UA.G..UA */ + DEF -379 -679 -889 -679 + -939 -1268 -1568 -1778 -1568 + -249 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@.C..GC */ + DEF DEF DEF DEF DEF + -929 -929 -929 -929 -929 + -359 -359 -359 -359 -359 + -789 -789 -789 -789 -789 + -549 -549 -549 -549 -549 +/* @.G..GC */ + DEF DEF DEF DEF DEF + -609 -609 -609 -609 -609 + -359 -359 -359 -359 -359 + -669 -669 -669 -669 -669 + -549 -549 -549 -549 -549 +/* @.U..GC */ + DEF DEF DEF DEF DEF + -929 -929 -929 -929 -929 + -439 -439 -439 -439 -439 + -789 -789 -789 -789 -789 + -619 -619 -619 -619 -619 +/* @.@..GU */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..GU */ + DEF DEF DEF DEF DEF + -479 -479 -479 -479 -479 + -309 -309 -309 -309 -309 + -389 -389 -389 -389 -389 + -379 -379 -379 -379 -379 +/* @.C..GU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.G..GU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 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-100 + -100 -100 -100 -100 -100 +/* @.A..AU */ + DEF DEF DEF DEF DEF + -479 -479 -479 -479 -479 + -309 -309 -309 -309 -309 + -389 -389 -389 -389 -389 + -379 -379 -379 -379 -379 +/* @.C..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.G..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.U..AU */ + DEF DEF DEF DEF DEF + -649 -649 -649 -649 -649 + -289 -289 -289 -289 -289 + -739 -739 -739 -739 -739 + -379 -379 -379 -379 -379 +/* @.@..UA */ + DEF DEF DEF DEF DEF + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 + -100 -100 -100 -100 -100 +/* @.A..UA */ + DEF DEF DEF DEF DEF + -449 -449 -449 -449 -449 + -479 -479 -479 -479 -479 + -429 -429 -429 -429 -429 + -329 -329 -329 -329 -329 +/* @.C..UA */ + DEF DEF DEF DEF DEF + -679 -679 -679 -679 -679 + -559 -559 -559 -559 -559 + -729 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GC.GU..UA */ + 200 200 200 200 + 170 200 210 150 + 130 200 120 -70 + 200 200 190 180 +/* GC.UA..UA */ + 200 270 30 220 + 200 160 -110 70 + 200 200 10 190 + 200 200 200 200 +/* GC.UC..UA */ + 200 210 -70 120 + 200 210 30 120 + 200 200 200 200 + 200 210 30 120 +/* GC.UG..UA */ + 200 200 10 190 + 200 200 200 200 + 200 200 -30 150 + 200 30 -350 20 +/* GC.UU..UA */ + 200 200 200 200 + 200 180 0 90 + 200 150 -220 150 + 200 120 30 30 +/* GC.AA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.AC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.AG.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.AU.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.CA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.CC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* GC.CG.. @ */ + 340 340 340 340 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340 340 340 340 + 340 340 340 340 +/* @.UA..UA */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UC..UA */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UG..UA */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UU..UA */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.AA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.AC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.AG.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.AU.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.CA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.CC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.CG.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.CU.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.GA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.GC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.GG.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.GU.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UA.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UC.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UG.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 +/* @.UU.. @ */ + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + 340 340 340 340 + +# int22_enthalpies +/* CG.AA..CG */ + -2058 -1978 -2058 -2058 + -1548 -1468 -1548 -1548 + -1968 -1888 -1968 -1968 + -1838 -1758 -1838 -1838 +/* CG.AC..CG */ + -1978 -1898 -1978 -1978 + -1478 -1398 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-569 -499 -569 -719 + -569 -499 -569 -719 + -569 -499 -569 -719 +/* CG.CU.. @ */ + -569 -499 -569 -719 + -569 -499 -569 -719 + -569 -499 -569 -719 + -569 -499 -569 -719 +/* CG.GA.. @ */ + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 +/* CG.GC.. @ */ + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 +/* CG.GG.. @ */ + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 +/* CG.GU.. @ */ + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 + -989 -989 -989 -989 +/* CG.UA.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* CG.UC.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* CG.UG.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* CG.UU.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 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GC.GC..GC */ + -1588 -1618 -1498 -1618 + -1018 -1048 -928 -1048 + -1448 -1478 -1358 -1478 + -1208 -1238 -1118 -1238 +/* GC.GG..GC */ + -1268 -1298 -1178 -1298 + -1018 -1048 -928 -1048 + -1328 -1358 -1238 -1358 + -1208 -1238 -1118 -1238 +/* GC.GU..GC */ + -1588 -1618 -1498 -1618 + -1098 -1128 -1008 -1128 + -1448 -1478 -1358 -3080 + -1278 -1308 -1188 -1308 +/* GC.UA..GC */ + -1018 -1018 -1018 -1088 + -1218 -1218 -1218 -1288 + -1208 -1208 -1208 -1278 + -998 -998 -998 -1068 +/* GC.UC..GC */ + -1378 -1378 -1378 -1448 + -808 -808 -808 -878 + -1238 -1238 -1238 -1308 + -998 -998 -998 -1068 +/* GC.UG..GC */ + -1058 -1058 -1058 -1128 + -808 -808 -808 -878 + -1118 -1118 -1118 -1188 + -998 -998 -998 -1068 +/* GC.UU..GC */ + -1378 -1378 -1378 -1448 + -888 -888 -888 -958 + -1238 -1238 -1238 -1308 + -1068 -1068 -1068 -1138 +/* GC.AA..GU */ + -948 -1308 -988 -1308 + -778 -1138 -818 -1138 + -858 -1218 -898 -1218 + -848 -1208 -888 -1208 +/* GC.AC..GU */ + -1118 -1478 -1158 -1478 + -758 -1118 -798 -1118 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*/ + -1428 -1658 -1918 -1618 + -918 -1148 -1408 -1108 + -1338 -1568 -1828 -1528 + -1208 -1438 -1698 -1398 +/* UA.AU..CG */ + -1428 -1658 -1918 -1618 + -1068 -1298 -1558 -1258 + -1338 -1568 -1828 -1528 + -1258 -1488 -1748 -1448 +/* UA.CA..CG */ + -1458 -1538 -1228 -1208 + -948 -1028 -718 -698 + -1368 -1448 -1138 -1118 + -1238 -1318 -1008 -988 +/* UA.CC..CG */ + -1378 -1458 -1148 -1128 + -878 -958 -648 -628 + -1368 -1448 -1138 -1118 + -1168 -1248 -938 -918 +/* UA.CG..CG */ + -1458 -1538 -1228 -1208 + -948 -1028 -718 -698 + -1368 -1448 -1138 -1118 + -1238 -1318 -1008 -988 +/* UA.CU..CG */ + -1458 -1538 -1228 -1208 + -1098 -1178 -868 -848 + -1368 -1448 -1138 -1118 + -1288 -1368 -1058 -1038 +/* UA.GA..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 -1198 + -1318 -1618 -1828 -1618 + -1188 -1488 -1698 -1488 +/* UA.GC..CG */ + -1328 -1628 -1838 -1628 + -828 -1128 -1338 -1128 + -1318 -1618 -1828 -1618 + -1118 -1418 -1628 -1418 +/* UA.GG..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 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UA.AU..GC */ + -1278 -1508 -1768 -1468 + -788 -1018 -1278 -978 + -1138 -1368 -1628 -1328 + -968 -1198 -1458 -1158 +/* UA.CA..GC */ + -948 -1028 -718 -698 + -1148 -1228 -918 -898 + -1138 -1218 -908 -888 + -928 -1008 -698 -678 +/* UA.CC..GC */ + -1308 -1388 -1078 -1058 + -738 -818 -508 -488 + -1168 -1248 -938 -918 + -928 -1008 -698 -678 +/* UA.CG..GC */ + -988 -1068 -758 -738 + -738 -818 -508 -488 + -1048 -1128 -818 -798 + -928 -1008 -698 -678 +/* UA.CU..GC */ + -1308 -1388 -1078 -1058 + -818 -898 -588 -568 + -1168 -1248 -938 -918 + -998 -1078 -768 -748 +/* UA.GA..GC */ + -898 -1198 -1408 -1198 + -1098 -1398 -1608 -1398 + -1088 -1388 -1598 -1388 + -878 -1178 -1388 -1178 +/* UA.GC..GC */ + -1258 -1558 -1768 -1558 + -688 -988 -1198 -988 + -1118 -1418 -1628 -1418 + -878 -1178 -1388 -1178 +/* UA.GG..GC */ + -938 -1238 -1448 -1238 + -688 -988 -1198 -988 + -998 -1298 -1508 -1298 + -878 -1178 -1388 -1178 +/* UA.GU..GC */ + -1258 -1558 -1768 -1558 + -768 -1068 -1278 -1068 + -1118 -1418 -1628 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-758 -838 -528 -508 +/* UA.CC..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CG..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CU..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.GA..GU */ + -808 -1108 -1318 -1108 + -638 -938 -1148 -938 + -718 -1018 -1228 -1018 + -708 -1008 -1218 -1008 +/* UA.GC..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GG..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GU..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.UA..GU */ + -708 -568 -708 -569 + -538 -398 -538 -399 + -618 -478 -618 -479 + -608 -468 -608 -469 +/* UA.UC..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UG..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UU..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.AA..UG */ + -1118 -1348 -1608 -1308 + -878 -1108 -1368 -1068 + -1058 -1288 -1548 -1248 + -948 -1178 -1438 -1138 +/* UA.AC..UG */ + -1188 -1418 -1678 -1378 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -838 -1068 -1328 -1028 +/* UA.AG..UG */ + -1358 -1588 -1848 -1548 + -758 -988 -1248 -948 + -1318 -1548 -1808 -1508 + -948 -1178 -1438 -1138 +/* UA.AU..UG */ + -1208 -1438 -1698 -1398 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -758 -988 -1248 -948 +/* UA.CA..UG */ + -1148 -1228 -918 -898 + -908 -988 -678 -658 + -1088 -1168 -858 -838 + -978 -1058 -748 -728 +/* UA.CC..UG */ + -1218 -1298 -988 -968 + -908 -988 -678 -658 + -1238 -1318 -1008 -988 + -868 -948 -638 -618 +/* UA.CG..UG */ + -1388 -1468 -1158 -1138 + -788 -868 -558 -538 + -1348 -1428 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-449 -679 -939 -639 + -449 -679 -939 -639 +/* UA.CA.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CC.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CG.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CU.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.GA.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GC.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GG.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GU.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.UA.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UC.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UG.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UU.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* @.AA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.AC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.AG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.AU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.CA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.CC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.CG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.CU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.GA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.GC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.GG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.GU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.UA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.UC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.UG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.UU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.AA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.AC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.AG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.AU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.CA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.CC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.CG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.CU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.GA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.GC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.GG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.GU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.UA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.UC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.UG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.UU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.AA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.AC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.CC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.GC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.UC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.AC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.AG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.AU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.CA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.CC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.CG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.CU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.GA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.GC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.GG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.GU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.UA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.UC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.UG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.UU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.AA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.AC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.CC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.GC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.UC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.AC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.AG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.AU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.CA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.CC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.CG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.CU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.GA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.GC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.GG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.GU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.UA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.UC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.UG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.UU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.AA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + +# hairpin + INF INF INF 570 560 560 540 590 560 640 + 650 660 670 678 686 694 701 707 713 719 + 725 730 735 740 744 749 753 757 761 765 + 769 + +# bulge + INF 380 280 320 360 400 440 459 470 480 + 490 500 510 519 527 534 541 548 554 560 + 565 571 576 580 585 589 594 598 602 605 + 609 + +# internal_loop + INF INF 410 510 170 180 200 220 230 240 + 250 260 270 278 286 294 301 307 313 319 + 325 330 335 340 345 349 353 357 361 365 + 369 + +# ML_params +/* F = cu*n_unpaired + cc + ci*loop_degree (+TermAU) */ +/* cu cc ci TerminalAU */ + 0 340 40 50 + +# NINIO +/* Ninio = MIN(max, m*|n1-n2| */ +/* m max */ + 50 300 + +# Tetraloops + GGGGAC -300 + GGUGAC -300 + CGAAAG -300 + GGAGAC -300 + CGCAAG -300 + GGAAAC -300 + CGGAAG -300 + CUUCGG -300 + CGUGAG -300 + CGAAGG -250 + CUACGG -250 + GGCAAC -250 + CGCGAG -250 + UGAGAG -250 + CGAGAG -200 + AGAAAU -200 + CGUAAG -200 + CUAACG -200 + UGAAAG -200 + GGAAGC -150 + GGGAAC -150 + UGAAAA -150 + AGCAAU -150 + AGUAAU -150 + CGGGAG -150 + AGUGAU -150 + GGCGAC -150 + GGGAGC -150 + GUGAAC -150 + UGGAAA -150 + +# Triloops + +#END diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/depcomp b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/depcomp new file mode 100755 index 00000000..11e2d3bf --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/depcomp @@ -0,0 +1,522 @@ +#! /bin/sh +# depcomp - compile a program generating dependencies as side-effects + +scriptversion=2004-05-31.23 + +# Copyright (C) 1999, 2000, 2003, 2004 Free Software Foundation, Inc. + +# This program is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2, or (at your option) +# any later version. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the +# GNU General Public License for more details. + +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA +# 02111-1307, USA. + +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +# Originally written by Alexandre Oliva . + +case $1 in + '') + echo "$0: No command. Try \`$0 --help' for more information." 1>&2 + exit 1; + ;; + -h | --h*) + cat <<\EOF +Usage: depcomp [--help] [--version] PROGRAM [ARGS] + +Run PROGRAMS ARGS to compile a file, generating dependencies +as side-effects. + +Environment variables: + depmode Dependency tracking mode. + source Source file read by `PROGRAMS ARGS'. + object Object file output by `PROGRAMS ARGS'. + DEPDIR directory where to store dependencies. + depfile Dependency file to output. + tmpdepfile Temporary file to use when outputing dependencies. + libtool Whether libtool is used (yes/no). + +Report bugs to . +EOF + exit 0 + ;; + -v | --v*) + echo "depcomp $scriptversion" + exit 0 + ;; +esac + +if test -z "$depmode" || test -z "$source" || test -z "$object"; then + echo "depcomp: Variables source, object and depmode must be set" 1>&2 + exit 1 +fi + +# Dependencies for sub/bar.o or sub/bar.obj go into sub/.deps/bar.Po. +depfile=${depfile-`echo "$object" | + sed 's|[^\\/]*$|'${DEPDIR-.deps}'/&|;s|\.\([^.]*\)$|.P\1|;s|Pobj$|Po|'`} +tmpdepfile=${tmpdepfile-`echo "$depfile" | sed 's/\.\([^.]*\)$/.T\1/'`} + +rm -f "$tmpdepfile" + +# Some modes work just like other modes, but use different flags. We +# parameterize here, but still list the modes in the big case below, +# to make depend.m4 easier to write. Note that we *cannot* use a case +# here, because this file can only contain one case statement. +if test "$depmode" = hp; then + # HP compiler uses -M and no extra arg. + gccflag=-M + depmode=gcc +fi + +if test "$depmode" = dashXmstdout; then + # This is just like dashmstdout with a different argument. + dashmflag=-xM + depmode=dashmstdout +fi + +case "$depmode" in +gcc3) +## gcc 3 implements dependency tracking that does exactly what +## we want. Yay! Note: for some reason libtool 1.4 doesn't like +## it if -MD -MP comes after the -MF stuff. Hmm. + "$@" -MT "$object" -MD -MP -MF "$tmpdepfile" + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + mv "$tmpdepfile" "$depfile" + ;; + +gcc) +## There are various ways to get dependency output from gcc. Here's +## why we pick this rather obscure method: +## - Don't want to use -MD because we'd like the dependencies to end +## up in a subdir. Having to rename by hand is ugly. +## (We might end up doing this anyway to support other compilers.) +## - The DEPENDENCIES_OUTPUT environment variable makes gcc act like +## -MM, not -M (despite what the docs say). +## - Using -M directly means running the compiler twice (even worse +## than renaming). + if test -z "$gccflag"; then + gccflag=-MD, + fi + "$@" -Wp,"$gccflag$tmpdepfile" + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + rm -f "$depfile" + echo "$object : \\" > "$depfile" + alpha=ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz +## The second -e expression handles DOS-style file names with drive letters. + sed -e 's/^[^:]*: / /' \ + -e 's/^['$alpha']:\/[^:]*: / /' < "$tmpdepfile" >> "$depfile" +## This next piece of magic avoids the `deleted header file' problem. +## The problem is that when a header file which appears in a .P file +## is deleted, the dependency causes make to die (because there is +## typically no way to rebuild the header). We avoid this by adding +## dummy dependencies for each header file. Too bad gcc doesn't do +## this for us directly. + tr ' ' ' +' < "$tmpdepfile" | +## Some versions of gcc put a space before the `:'. On the theory +## that the space means something, we add a space to the output as +## well. +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +hp) + # This case exists only to let depend.m4 do its work. It works by + # looking at the text of this script. This case will never be run, + # since it is checked for above. + exit 1 + ;; + +sgi) + if test "$libtool" = yes; then + "$@" "-Wp,-MDupdate,$tmpdepfile" + else + "$@" -MDupdate "$tmpdepfile" + fi + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + rm -f "$depfile" + + if test -f "$tmpdepfile"; then # yes, the sourcefile depend on other files + echo "$object : \\" > "$depfile" + + # Clip off the initial element (the dependent). Don't try to be + # clever and replace this with sed code, as IRIX sed won't handle + # lines with more than a fixed number of characters (4096 in + # IRIX 6.2 sed, 8192 in IRIX 6.5). We also remove comment lines; + # the IRIX cc adds comments like `#:fec' to the end of the + # dependency line. + tr ' ' ' +' < "$tmpdepfile" \ + | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' | \ + tr ' +' ' ' >> $depfile + echo >> $depfile + + # The second pass generates a dummy entry for each header file. + tr ' ' ' +' < "$tmpdepfile" \ + | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' -e 's/$/:/' \ + >> $depfile + else + # The sourcefile does not contain any dependencies, so just + # store a dummy comment line, to avoid errors with the Makefile + # "include basename.Plo" scheme. + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +aix) + # The C for AIX Compiler uses -M and outputs the dependencies + # in a .u file. In older versions, this file always lives in the + # current directory. Also, the AIX compiler puts `$object:' at the + # start of each line; $object doesn't have directory information. + # Version 6 uses the directory in both cases. + stripped=`echo "$object" | sed 's/\(.*\)\..*$/\1/'` + tmpdepfile="$stripped.u" + if test "$libtool" = yes; then + "$@" -Wc,-M + else + "$@" -M + fi + stat=$? + + if test -f "$tmpdepfile"; then : + else + stripped=`echo "$stripped" | sed 's,^.*/,,'` + tmpdepfile="$stripped.u" + fi + + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + + if test -f "$tmpdepfile"; then + outname="$stripped.o" + # Each line is of the form `foo.o: dependent.h'. + # Do two passes, one to just change these to + # `$object: dependent.h' and one to simply `dependent.h:'. + sed -e "s,^$outname:,$object :," < "$tmpdepfile" > "$depfile" + sed -e "s,^$outname: \(.*\)$,\1:," < "$tmpdepfile" >> "$depfile" + else + # The sourcefile does not contain any dependencies, so just + # store a dummy comment line, to avoid errors with the Makefile + # "include basename.Plo" scheme. + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +icc) + # Intel's C compiler understands `-MD -MF file'. However on + # icc -MD -MF foo.d -c -o sub/foo.o sub/foo.c + # ICC 7.0 will fill foo.d with something like + # foo.o: sub/foo.c + # foo.o: sub/foo.h + # which is wrong. We want: + # sub/foo.o: sub/foo.c + # sub/foo.o: sub/foo.h + # sub/foo.c: + # sub/foo.h: + # ICC 7.1 will output + # foo.o: sub/foo.c sub/foo.h + # and will wrap long lines using \ : + # foo.o: sub/foo.c ... \ + # sub/foo.h ... \ + # ... + + "$@" -MD -MF "$tmpdepfile" + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile" + exit $stat + fi + rm -f "$depfile" + # Each line is of the form `foo.o: dependent.h', + # or `foo.o: dep1.h dep2.h \', or ` dep3.h dep4.h \'. + # Do two passes, one to just change these to + # `$object: dependent.h' and one to simply `dependent.h:'. + sed "s,^[^:]*:,$object :," < "$tmpdepfile" > "$depfile" + # Some versions of the HPUX 10.20 sed can't process this invocation + # correctly. Breaking it into two sed invocations is a workaround. + sed 's,^[^:]*: \(.*\)$,\1,;s/^\\$//;/^$/d;/:$/d' < "$tmpdepfile" | + sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +tru64) + # The Tru64 compiler uses -MD to generate dependencies as a side + # effect. `cc -MD -o foo.o ...' puts the dependencies into `foo.o.d'. + # At least on Alpha/Redhat 6.1, Compaq CCC V6.2-504 seems to put + # dependencies in `foo.d' instead, so we check for that too. + # Subdirectories are respected. + dir=`echo "$object" | sed -e 's|/[^/]*$|/|'` + test "x$dir" = "x$object" && dir= + base=`echo "$object" | sed -e 's|^.*/||' -e 's/\.o$//' -e 's/\.lo$//'` + + if test "$libtool" = yes; then + # Dependencies are output in .lo.d with libtool 1.4. + # With libtool 1.5 they are output both in $dir.libs/$base.o.d + # and in $dir.libs/$base.o.d and $dir$base.o.d. We process the + # latter, because the former will be cleaned when $dir.libs is + # erased. + tmpdepfile1="$dir.libs/$base.lo.d" + tmpdepfile2="$dir$base.o.d" + tmpdepfile3="$dir.libs/$base.d" + "$@" -Wc,-MD + else + tmpdepfile1="$dir$base.o.d" + tmpdepfile2="$dir$base.d" + tmpdepfile3="$dir$base.d" + "$@" -MD + fi + + stat=$? + if test $stat -eq 0; then : + else + rm -f "$tmpdepfile1" "$tmpdepfile2" "$tmpdepfile3" + exit $stat + fi + + if test -f "$tmpdepfile1"; then + tmpdepfile="$tmpdepfile1" + elif test -f "$tmpdepfile2"; then + tmpdepfile="$tmpdepfile2" + else + tmpdepfile="$tmpdepfile3" + fi + if test -f "$tmpdepfile"; then + sed -e "s,^.*\.[a-z]*:,$object:," < "$tmpdepfile" > "$depfile" + # That's a tab and a space in the []. + sed -e 's,^.*\.[a-z]*:[ ]*,,' -e 's,$,:,' < "$tmpdepfile" >> "$depfile" + else + echo "#dummy" > "$depfile" + fi + rm -f "$tmpdepfile" + ;; + +#nosideeffect) + # This comment above is used by automake to tell side-effect + # dependency tracking mechanisms from slower ones. + +dashmstdout) + # Important note: in order to support this mode, a compiler *must* + # always write the preprocessed file to stdout, regardless of -o. + "$@" || exit $? + + # Remove the call to Libtool. + if test "$libtool" = yes; then + while test $1 != '--mode=compile'; do + shift + done + shift + fi + + # Remove `-o $object'. + IFS=" " + for arg + do + case $arg in + -o) + shift + ;; + $object) + shift + ;; + *) + set fnord "$@" "$arg" + shift # fnord + shift # $arg + ;; + esac + done + + test -z "$dashmflag" && dashmflag=-M + # Require at least two characters before searching for `:' + # in the target name. This is to cope with DOS-style filenames: + # a dependency such as `c:/foo/bar' could be seen as target `c' otherwise. + "$@" $dashmflag | + sed 's:^[ ]*[^: ][^:][^:]*\:[ ]*:'"$object"'\: :' > "$tmpdepfile" + rm -f "$depfile" + cat < "$tmpdepfile" > "$depfile" + tr ' ' ' +' < "$tmpdepfile" | \ +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +dashXmstdout) + # This case only exists to satisfy depend.m4. It is never actually + # run, as this mode is specially recognized in the preamble. + exit 1 + ;; + +makedepend) + "$@" || exit $? + # Remove any Libtool call + if test "$libtool" = yes; then + while test $1 != '--mode=compile'; do + shift + done + shift + fi + # X makedepend + shift + cleared=no + for arg in "$@"; do + case $cleared in + no) + set ""; shift + cleared=yes ;; + esac + case "$arg" in + -D*|-I*) + set fnord "$@" "$arg"; shift ;; + # Strip any option that makedepend may not understand. Remove + # the object too, otherwise makedepend will parse it as a source file. + -*|$object) + ;; + *) + set fnord "$@" "$arg"; shift ;; + esac + done + obj_suffix="`echo $object | sed 's/^.*\././'`" + touch "$tmpdepfile" + ${MAKEDEPEND-makedepend} -o"$obj_suffix" -f"$tmpdepfile" "$@" + rm -f "$depfile" + cat < "$tmpdepfile" > "$depfile" + sed '1,2d' "$tmpdepfile" | tr ' ' ' +' | \ +## Some versions of the HPUX 10.20 sed can't process this invocation +## correctly. Breaking it into two sed invocations is a workaround. + sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" "$tmpdepfile".bak + ;; + +cpp) + # Important note: in order to support this mode, a compiler *must* + # always write the preprocessed file to stdout. + "$@" || exit $? + + # Remove the call to Libtool. + if test "$libtool" = yes; then + while test $1 != '--mode=compile'; do + shift + done + shift + fi + + # Remove `-o $object'. + IFS=" " + for arg + do + case $arg in + -o) + shift + ;; + $object) + shift + ;; + *) + set fnord "$@" "$arg" + shift # fnord + shift # $arg + ;; + esac + done + + "$@" -E | + sed -n '/^# [0-9][0-9]* "\([^"]*\)".*/ s:: \1 \\:p' | + sed '$ s: \\$::' > "$tmpdepfile" + rm -f "$depfile" + echo "$object : \\" > "$depfile" + cat < "$tmpdepfile" >> "$depfile" + sed < "$tmpdepfile" '/^$/d;s/^ //;s/ \\$//;s/$/ :/' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +msvisualcpp) + # Important note: in order to support this mode, a compiler *must* + # always write the preprocessed file to stdout, regardless of -o, + # because we must use -o when running libtool. + "$@" || exit $? + IFS=" " + for arg + do + case "$arg" in + "-Gm"|"/Gm"|"-Gi"|"/Gi"|"-ZI"|"/ZI") + set fnord "$@" + shift + shift + ;; + *) + set fnord "$@" "$arg" + shift + shift + ;; + esac + done + "$@" -E | + sed -n '/^#line [0-9][0-9]* "\([^"]*\)"/ s::echo "`cygpath -u \\"\1\\"`":p' | sort | uniq > "$tmpdepfile" + rm -f "$depfile" + echo "$object : \\" > "$depfile" + . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s:: \1 \\:p' >> "$depfile" + echo " " >> "$depfile" + . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s::\1\::p' >> "$depfile" + rm -f "$tmpdepfile" + ;; + +none) + exec "$@" + ;; + +*) + echo "Unknown depmode $depmode" 1>&2 + exit 1 + ;; +esac + +exit 0 + +# Local Variables: +# mode: shell-script +# sh-indentation: 2 +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "scriptversion=" +# time-stamp-format: "%:y-%02m-%02d.%02H" +# time-stamp-end: "$" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/install-sh b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/install-sh new file mode 100755 index 00000000..b777f124 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/install-sh @@ -0,0 +1,322 @@ +#!/bin/sh +# install - install a program, script, or datafile + +scriptversion=2004-07-05.00 + +# This originates from X11R5 (mit/util/scripts/install.sh), which was +# later released in X11R6 (xc/config/util/install.sh) with the +# following copyright and license. +# +# Copyright (C) 1994 X Consortium +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to +# deal in the Software without restriction, including without limitation the +# rights to use, copy, modify, merge, publish, distribute, sublicense, and/or +# sell copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# X CONSORTIUM BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN +# AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNEC- +# TION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. +# +# Except as contained in this notice, the name of the X Consortium shall not +# be used in advertising or otherwise to promote the sale, use or other deal- +# ings in this Software without prior written authorization from the X Consor- +# tium. +# +# +# FSF changes to this file are in the public domain. +# +# Calling this script install-sh is preferred over install.sh, to prevent +# `make' implicit rules from creating a file called install from it +# when there is no Makefile. +# +# This script is compatible with the BSD install script, but was written +# from scratch. It can only install one file at a time, a restriction +# shared with many OS's install programs. + +# set DOITPROG to echo to test this script + +# Don't use :- since 4.3BSD and earlier shells don't like it. +doit="${DOITPROG-}" + +# put in absolute paths if you don't have them in your path; or use env. vars. + +mvprog="${MVPROG-mv}" +cpprog="${CPPROG-cp}" +chmodprog="${CHMODPROG-chmod}" +chownprog="${CHOWNPROG-chown}" +chgrpprog="${CHGRPPROG-chgrp}" +stripprog="${STRIPPROG-strip}" +rmprog="${RMPROG-rm}" +mkdirprog="${MKDIRPROG-mkdir}" + +chmodcmd="$chmodprog 0755" +chowncmd= +chgrpcmd= +stripcmd= +rmcmd="$rmprog -f" +mvcmd="$mvprog" +src= +dst= +dir_arg= +dstarg= +no_target_directory= + +usage="Usage: $0 [OPTION]... [-T] SRCFILE DSTFILE + or: $0 [OPTION]... SRCFILES... DIRECTORY + or: $0 [OPTION]... -t DIRECTORY SRCFILES... + or: $0 [OPTION]... -d DIRECTORIES... + +In the 1st form, copy SRCFILE to DSTFILE. +In the 2nd and 3rd, copy all SRCFILES to DIRECTORY. +In the 4th, create DIRECTORIES. + +Options: +-c (ignored) +-d create directories instead of installing files. +-g GROUP $chgrpprog installed files to GROUP. +-m MODE $chmodprog installed files to MODE. +-o USER $chownprog installed files to USER. +-s $stripprog installed files. +-t DIRECTORY install into DIRECTORY. +-T report an error if DSTFILE is a directory. +--help display this help and exit. +--version display version info and exit. + +Environment variables override the default commands: + CHGRPPROG CHMODPROG CHOWNPROG CPPROG MKDIRPROG MVPROG RMPROG STRIPPROG +" + +while test -n "$1"; do + case $1 in + -c) shift + continue;; + + -d) dir_arg=true + shift + continue;; + + -g) chgrpcmd="$chgrpprog $2" + shift + shift + continue;; + + --help) echo "$usage"; exit 0;; + + -m) chmodcmd="$chmodprog $2" + shift + shift + continue;; + + -o) chowncmd="$chownprog $2" + shift + shift + continue;; + + -s) stripcmd=$stripprog + shift + continue;; + + -t) dstarg=$2 + shift + shift + continue;; + + -T) no_target_directory=true + shift + continue;; + + --version) echo "$0 $scriptversion"; exit 0;; + + *) # When -d is used, all remaining arguments are directories to create. + # When -t is used, the destination is already specified. + test -n "$dir_arg$dstarg" && break + # Otherwise, the last argument is the destination. Remove it from $@. + for arg + do + if test -n "$dstarg"; then + # $@ is not empty: it contains at least $arg. + set fnord "$@" "$dstarg" + shift # fnord + fi + shift # arg + dstarg=$arg + done + break;; + esac +done + +if test -z "$1"; then + if test -z "$dir_arg"; then + echo "$0: no input file specified." >&2 + exit 1 + fi + # It's OK to call `install-sh -d' without argument. + # This can happen when creating conditional directories. + exit 0 +fi + +for src +do + # Protect names starting with `-'. + case $src in + -*) src=./$src ;; + esac + + if test -n "$dir_arg"; then + dst=$src + src= + + if test -d "$dst"; then + mkdircmd=: + chmodcmd= + else + mkdircmd=$mkdirprog + fi + else + # Waiting for this to be detected by the "$cpprog $src $dsttmp" command + # might cause directories to be created, which would be especially bad + # if $src (and thus $dsttmp) contains '*'. + if test ! -f "$src" && test ! -d "$src"; then + echo "$0: $src does not exist." >&2 + exit 1 + fi + + if test -z "$dstarg"; then + echo "$0: no destination specified." >&2 + exit 1 + fi + + dst=$dstarg + # Protect names starting with `-'. + case $dst in + -*) dst=./$dst ;; + esac + + # If destination is a directory, append the input filename; won't work + # if double slashes aren't ignored. + if test -d "$dst"; then + if test -n "$no_target_directory"; then + echo "$0: $dstarg: Is a directory" >&2 + exit 1 + fi + dst=$dst/`basename "$src"` + fi + fi + + # This sed command emulates the dirname command. + dstdir=`echo "$dst" | sed -e 's,[^/]*$,,;s,/$,,;s,^$,.,'` + + # Make sure that the destination directory exists. + + # Skip lots of stat calls in the usual case. + if test ! -d "$dstdir"; then + defaultIFS=' + ' + IFS="${IFS-$defaultIFS}" + + oIFS=$IFS + # Some sh's can't handle IFS=/ for some reason. + IFS='%' + set - `echo "$dstdir" | sed -e 's@/@%@g' -e 's@^%@/@'` + IFS=$oIFS + + pathcomp= + + while test $# -ne 0 ; do + pathcomp=$pathcomp$1 + shift + if test ! -d "$pathcomp"; then + $mkdirprog "$pathcomp" + # mkdir can fail with a `File exist' error in case several + # install-sh are creating the directory concurrently. This + # is OK. + test -d "$pathcomp" || exit + fi + pathcomp=$pathcomp/ + done + fi + + if test -n "$dir_arg"; then + $doit $mkdircmd "$dst" \ + && { test -z "$chowncmd" || $doit $chowncmd "$dst"; } \ + && { test -z "$chgrpcmd" || $doit $chgrpcmd "$dst"; } \ + && { test -z "$stripcmd" || $doit $stripcmd "$dst"; } \ + && { test -z "$chmodcmd" || $doit $chmodcmd "$dst"; } + + else + dstfile=`basename "$dst"` + + # Make a couple of temp file names in the proper directory. + dsttmp=$dstdir/_inst.$$_ + rmtmp=$dstdir/_rm.$$_ + + # Trap to clean up those temp files at exit. + trap 'status=$?; rm -f "$dsttmp" "$rmtmp" && exit $status' 0 + trap '(exit $?); exit' 1 2 13 15 + + # Copy the file name to the temp name. + $doit $cpprog "$src" "$dsttmp" && + + # and set any options; do chmod last to preserve setuid bits. + # + # If any of these fail, we abort the whole thing. If we want to + # ignore errors from any of these, just make sure not to ignore + # errors from the above "$doit $cpprog $src $dsttmp" command. + # + { test -z "$chowncmd" || $doit $chowncmd "$dsttmp"; } \ + && { test -z "$chgrpcmd" || $doit $chgrpcmd "$dsttmp"; } \ + && { test -z "$stripcmd" || $doit $stripcmd "$dsttmp"; } \ + && { test -z "$chmodcmd" || $doit $chmodcmd "$dsttmp"; } && + + # Now rename the file to the real destination. + { $doit $mvcmd -f "$dsttmp" "$dstdir/$dstfile" 2>/dev/null \ + || { + # The rename failed, perhaps because mv can't rename something else + # to itself, or perhaps because mv is so ancient that it does not + # support -f. + + # Now remove or move aside any old file at destination location. + # We try this two ways since rm can't unlink itself on some + # systems and the destination file might be busy for other + # reasons. In this case, the final cleanup might fail but the new + # file should still install successfully. + { + if test -f "$dstdir/$dstfile"; then + $doit $rmcmd -f "$dstdir/$dstfile" 2>/dev/null \ + || $doit $mvcmd -f "$dstdir/$dstfile" "$rmtmp" 2>/dev/null \ + || { + echo "$0: cannot unlink or rename $dstdir/$dstfile" >&2 + (exit 1); exit + } + else + : + fi + } && + + # Now rename the file to the real destination. + $doit $mvcmd "$dsttmp" "$dstdir/$dstfile" + } + } + fi || { (exit 1); exit; } +done + +# The final little trick to "correctly" pass the exit status to the exit trap. +{ + (exit 0); exit +} + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "scriptversion=" +# time-stamp-format: "%:y-%02m-%02d.%02H" +# time-stamp-end: "$" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/LPfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/LPfold.Po new file mode 100755 index 00000000..115403fb --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/LPfold.Po @@ -0,0 +1,117 @@ +LPfold.o LPfold.o: LPfold.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h ../H/utils.h \ + ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h \ + /usr/include/ctype.h ../H/PS_dot.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +/usr/include/ctype.h: + +../H/PS_dot.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/Lfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/Lfold.Po new file mode 100755 index 00000000..3c8d7d29 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/Lfold.Po @@ -0,0 +1,114 @@ +Lfold.o Lfold.o: Lfold.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/utils.h ../H/energy_par.h \ + ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h ../H/params.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +../H/params.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/PS_dot.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/PS_dot.Po new file mode 100755 index 00000000..4737f985 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/PS_dot.Po @@ -0,0 +1,107 @@ +PS_dot.o PS_dot.o: PS_dot.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/ctype.h ../H/utils.h ../H/fold_vars.h ../H/PS_dot.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +../H/utils.h: + +../H/fold_vars.h: + +../H/PS_dot.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileAln.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileAln.Po new file mode 100755 index 00000000..d2252c51 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileAln.Po @@ -0,0 +1,112 @@ +ProfileAln.o ProfileAln.o: ProfileAln.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h ../H/dist_vars.h \ + ../H/fold_vars.h ../H/part_func.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h: + +../H/dist_vars.h: + +../H/fold_vars.h: + +../H/part_func.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileDist.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileDist.Po new file mode 100755 index 00000000..e8100ab8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/ProfileDist.Po @@ -0,0 +1,110 @@ +ProfileDist.o ProfileDist.o: ProfileDist.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + ../H/dist_vars.h ../H/fold_vars.h ../H/part_func.h ../H/utils.h \ + ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/dist_vars.h: + +../H/fold_vars.h: + +../H/part_func.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/RNAstruct.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/RNAstruct.Po new file mode 100755 index 00000000..1368e80c --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/RNAstruct.Po @@ -0,0 +1,91 @@ +RNAstruct.o RNAstruct.o: RNAstruct.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h ../H/utils.h \ + ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alifold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alifold.Po new file mode 100755 index 00000000..ce3ab297 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alifold.Po @@ -0,0 +1,116 @@ +alifold.o alifold.o: alifold.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/fold.h ../H/utils.h ../H/energy_par.h \ + ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h ../H/params.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/fold.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +../H/params.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alipfold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alipfold.Po new file mode 100755 index 00000000..139a3fdb --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/alipfold.Po @@ -0,0 +1,117 @@ +alipfold.o alipfold.o: alipfold.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h ../H/utils.h \ + ../config.h ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h \ + ../H/pair_mat.h /usr/include/ctype.h ../H/alifold.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h: + +../H/utils.h: + +../config.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +/usr/include/ctype.h: + +../H/alifold.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/aln_util.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/aln_util.Po new file mode 100755 index 00000000..0ac8cd1b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/aln_util.Po @@ -0,0 +1,108 @@ +aln_util.o aln_util.o: aln_util.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/errno.h /usr/include/bits/errno.h \ + /usr/include/linux/errno.h /usr/include/asm/errno.h \ + /usr/include/asm-x86_64/errno.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/ctype.h ../config.h ../H/utils.h ../H/fold_vars.h \ + ../H/pair_mat.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/errno.h: + +/usr/include/bits/errno.h: + +/usr/include/linux/errno.h: + +/usr/include/asm/errno.h: + +/usr/include/asm-x86_64/errno.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +../config.h: + +../H/utils.h: + +../H/fold_vars.h: + +../H/pair_mat.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/cofold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/cofold.Po new file mode 100755 index 00000000..cd55b652 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/cofold.Po @@ -0,0 +1,114 @@ +cofold.o cofold.o: cofold.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/utils.h ../H/energy_par.h \ + ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h ../H/params.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +../H/params.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/dist_vars.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/dist_vars.Po new file mode 100755 index 00000000..a863fbe4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/dist_vars.Po @@ -0,0 +1 @@ +dist_vars.o dist_vars.o: dist_vars.c diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/duplex.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/duplex.Po new file mode 100755 index 00000000..1403515f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/duplex.Po @@ -0,0 +1,117 @@ +duplex.o duplex.o: duplex.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/utils.h ../H/energy_par.h \ + ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h ../H/params.h \ + ../H/duplex.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +../H/params.h: + +../H/duplex.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/energy_par.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/energy_par.Po new file mode 100755 index 00000000..d5c288fc --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/energy_par.Po @@ -0,0 +1,5 @@ +energy_par.o energy_par.o: energy_par.c ../H/energy_const.h intloops.h + +../H/energy_const.h: + +intloops.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold.Po new file mode 100755 index 00000000..b3ecfa9d --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold.Po @@ -0,0 +1,117 @@ +fold.o fold.o: fold.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/ctype.h \ + /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h ../H/utils.h ../H/energy_par.h \ + ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h ../H/params.h \ + circfold.inc + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +../H/params.h: + +circfold.inc: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold_vars.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold_vars.Po new file mode 100755 index 00000000..8b95a0a3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/fold_vars.Po @@ -0,0 +1,61 @@ +fold_vars.o fold_vars.o: fold_vars.c /usr/include/string.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/endian.h /usr/include/bits/endian.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/stdlib.h \ + /usr/include/stdio.h /usr/include/libio.h /usr/include/_G_config.h \ + /usr/include/wchar.h /usr/include/bits/wchar.h /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h ../H/fold_vars.h + +/usr/include/string.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/stdlib.h: + +/usr/include/stdio.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +../H/fold_vars.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/inverse.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/inverse.Po new file mode 100755 index 00000000..026f8975 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/inverse.Po @@ -0,0 +1,112 @@ +inverse.o inverse.o: inverse.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + ../H/part_func.h ../H/fold.h ../H/utils.h ../config.h ../H/fold_vars.h \ + ../H/pair_mat.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/part_func.h: + +../H/fold.h: + +../H/utils.h: + +../config.h: + +../H/fold_vars.h: + +../H/pair_mat.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/list.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/list.Po new file mode 100755 index 00000000..bb19b185 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/list.Po @@ -0,0 +1,82 @@ +list.o list.o: list.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h ../H/utils.h ../config.h list.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +../H/utils.h: + +../config.h: + +list.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/naview.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/naview.Po new file mode 100755 index 00000000..aff4e4e5 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/naview.Po @@ -0,0 +1,100 @@ +naview.o naview.o: naview.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/params.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/params.Po new file mode 100755 index 00000000..5d501701 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/params.Po @@ -0,0 +1,110 @@ +params.o params.o: params.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h ../H/utils.h \ + ../H/params.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/utils.h: + +../H/params.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func.Po new file mode 100755 index 00000000..398c3b0e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func.Po @@ -0,0 +1,115 @@ +part_func.o part_func.o: part_func.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h ../H/utils.h \ + ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h \ + /usr/include/ctype.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +/usr/include/ctype.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func_co.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func_co.Po new file mode 100755 index 00000000..4865acac --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/part_func_co.Po @@ -0,0 +1,119 @@ +part_func_co.o part_func_co.o: part_func_co.c ../config.h \ + /usr/include/stdio.h /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h ../H/utils.h \ + ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h \ + /usr/include/ctype.h ../H/PS_dot.h ../H/part_func_co.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/float.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +/usr/include/ctype.h: + +../H/PS_dot.h: + +../H/part_func_co.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/read_epars.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/read_epars.Po new file mode 100755 index 00000000..6b03b665 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/read_epars.Po @@ -0,0 +1,110 @@ +read_epars.o read_epars.o: read_epars.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/ctype.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h ../H/utils.h ../config.h \ + ../H/energy_const.h ../H/energy_par.h ../H/energy_const.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/utils.h: + +../config.h: + +../H/energy_const.h: + +../H/energy_par.h: + +../H/energy_const.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/stringdist.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/stringdist.Po new file mode 100755 index 00000000..6e7c3b8b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/stringdist.Po @@ -0,0 +1,107 @@ +stringdist.o stringdist.o: stringdist.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h /usr/include/math.h \ + /usr/include/bits/huge_val.h /usr/include/bits/mathdef.h \ + /usr/include/bits/mathcalls.h /usr/include/bits/mathinline.h \ + ../H/edit_cost.h ../H/dist_vars.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/edit_cost.h: + +../H/dist_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/subopt.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/subopt.Po new file mode 100755 index 00000000..b4e825cc --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/subopt.Po @@ -0,0 +1,121 @@ +subopt.o subopt.o: subopt.c ../config.h /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/ctype.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h \ + /usr/include/math.h /usr/include/bits/huge_val.h \ + /usr/include/bits/mathdef.h /usr/include/bits/mathcalls.h \ + /usr/include/bits/mathinline.h ../H/fold.h ../H/utils.h \ + ../H/energy_par.h ../H/energy_const.h ../H/fold_vars.h ../H/pair_mat.h \ + list.h ../H/subopt.h ../H/params.h + +../config.h: + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/ctype.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/math.h: + +/usr/include/bits/huge_val.h: + +/usr/include/bits/mathdef.h: + +/usr/include/bits/mathcalls.h: + +/usr/include/bits/mathinline.h: + +../H/fold.h: + +../H/utils.h: + +../H/energy_par.h: + +../H/energy_const.h: + +../H/fold_vars.h: + +../H/pair_mat.h: + +list.h: + +../H/subopt.h: + +../H/params.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/treedist.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/treedist.Po new file mode 100755 index 00000000..afd7fdbd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/treedist.Po @@ -0,0 +1,95 @@ +treedist.o treedist.o: treedist.c /usr/include/stdio.h \ + /usr/include/features.h /usr/include/sys/cdefs.h \ + /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/string.h /usr/include/bits/string.h \ + /usr/include/bits/string2.h /usr/include/ctype.h ../H/edit_cost.h \ + ../H/dist_vars.h ../H/utils.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +/usr/include/ctype.h: + +../H/edit_cost.h: + +../H/dist_vars.h: + +../H/utils.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/utils.Po b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/utils.Po new file mode 100755 index 00000000..b9740d88 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/.deps/utils.Po @@ -0,0 +1,97 @@ +utils.o utils.o: utils.c /usr/include/stdio.h /usr/include/features.h \ + /usr/include/sys/cdefs.h /usr/include/gnu/stubs.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h \ + /usr/include/bits/types.h /usr/include/bits/wordsize.h \ + /usr/include/bits/typesizes.h /usr/include/libio.h \ + /usr/include/_G_config.h /usr/include/wchar.h /usr/include/bits/wchar.h \ + /usr/include/gconv.h \ + /usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h \ + /usr/include/bits/stdio_lim.h /usr/include/bits/sys_errlist.h \ + /usr/include/bits/stdio.h /usr/include/stdlib.h \ + /usr/include/sys/types.h /usr/include/time.h /usr/include/endian.h \ + /usr/include/bits/endian.h /usr/include/sys/select.h \ + /usr/include/bits/select.h /usr/include/bits/sigset.h \ + /usr/include/bits/time.h /usr/include/sys/sysmacros.h \ + /usr/include/bits/pthreadtypes.h /usr/include/bits/sched.h \ + /usr/include/alloca.h /usr/include/errno.h /usr/include/bits/errno.h \ + /usr/include/linux/errno.h /usr/include/asm/errno.h \ + /usr/include/asm-x86_64/errno.h /usr/include/string.h \ + /usr/include/bits/string.h /usr/include/bits/string2.h ../config.h + +/usr/include/stdio.h: + +/usr/include/features.h: + +/usr/include/sys/cdefs.h: + +/usr/include/gnu/stubs.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stddef.h: + +/usr/include/bits/types.h: + +/usr/include/bits/wordsize.h: + +/usr/include/bits/typesizes.h: + +/usr/include/libio.h: + +/usr/include/_G_config.h: + +/usr/include/wchar.h: + +/usr/include/bits/wchar.h: + +/usr/include/gconv.h: + +/usr/lib/gcc/x86_64-redhat-linux/3.4.5/include/stdarg.h: + +/usr/include/bits/stdio_lim.h: + +/usr/include/bits/sys_errlist.h: + +/usr/include/bits/stdio.h: + +/usr/include/stdlib.h: + +/usr/include/sys/types.h: + +/usr/include/time.h: + +/usr/include/endian.h: + +/usr/include/bits/endian.h: + +/usr/include/sys/select.h: + +/usr/include/bits/select.h: + +/usr/include/bits/sigset.h: + +/usr/include/bits/time.h: + +/usr/include/sys/sysmacros.h: + +/usr/include/bits/pthreadtypes.h: + +/usr/include/bits/sched.h: + +/usr/include/alloca.h: + +/usr/include/errno.h: + +/usr/include/bits/errno.h: + +/usr/include/linux/errno.h: + +/usr/include/asm/errno.h: + +/usr/include/asm-x86_64/errno.h: + +/usr/include/string.h: + +/usr/include/bits/string.h: + +/usr/include/bits/string2.h: + +../config.h: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/LPfold.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/LPfold.c new file mode 100755 index 00000000..3040f791 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/LPfold.c @@ -0,0 +1,752 @@ +/* Last changed Time-stamp: <2006-01-16 10:43:16 ivo> */ +/* + local pair probabilities for RNA secondary structures + + Stephan Bernhart, Ivo L Hofacker + Vienna RNA package +*/ +/* + todo: compute energy z-score for each window + +*/ +#include +#include +#include +#include +#include +#include /* #defines FLT_MAX ... */ +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "PS_dot.h" +/*@unused@*/ +static char rcsid[] UNUSED = "$Id: LPfold.c,v 1.2 2006/01/16 09:49:07 ivo Exp $"; + +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define PUBLIC +#define PRIVATE static + +static int num_p=0; /*for counting basepairs*/ +PUBLIC int pfl_fold(char *seq, int winSize, float cutoff, struct plist **pl); +PUBLIC void init_pf_foldLP(int length); +PUBLIC void free_pf_arraysLP(void); +PUBLIC void update_pf_paramsLP(int length); +/*PUBLIC int st_back=0;*/ +PRIVATE void scale_pf_params(unsigned int length); +PRIVATE void get_arrays(unsigned int length); +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1); +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string); +/*PRIVATE void make_ptypes(const short *S, const char *structure);*/ +/*new functions*/ +PRIVATE void GetPtype(int j, int winSize,const short *S, int n); +PRIVATE void FreeOldArrays(int i); +PRIVATE void GetNewArrays(int j, int winSize); +PRIVATE void printpbar(FLT_OR_DBL **prb,int winSize, int i, int n, float cutoff); +PRIVATE struct plist *get_plistW(struct plist *pl, int length, double cutoff, int start, FLT_OR_DBL **Tpr, int winSize); +/*end*/ +PRIVATE FLT_OR_DBL expMLclosing, expMLintern[NBPAIRS+1], *expMLbase; +PRIVATE FLT_OR_DBL expTermAU; +PRIVATE FLT_OR_DBL expdangle5[NBPAIRS+1][5], expdangle3[NBPAIRS+1][5]; +PRIVATE FLT_OR_DBL lxc, exptetra[40], expTriloop[40]; +PRIVATE FLT_OR_DBL expstack[NBPAIRS+1][NBPAIRS+1]; +PRIVATE FLT_OR_DBL expmismatchI[NBPAIRS+1][5][5], + expmismatchH[NBPAIRS+1][5][5], expmismatchM[NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint11[NBPAIRS+1][NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint21[NBPAIRS+1][NBPAIRS+1][5][5][5]; +PRIVATE FLT_OR_DBL expint22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; +PRIVATE FLT_OR_DBL *exphairpin; +PRIVATE FLT_OR_DBL expbulge[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expinternal[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expninio[5][MAXLOOP+1]; +PRIVATE FLT_OR_DBL **q, **qb, **qm, *qm1, *qqm, *qqm1, *qq, *qq1, **pR; +PRIVATE FLT_OR_DBL *prml, *prm_l, *prm_l1, *q1k, *qln; +PRIVATE FLT_OR_DBL *scale; +PRIVATE char **ptype; /* precomputed array of pair types */ +PRIVATE int *jindx; +PRIVATE int init_length; /* length in last call to init_pf_fold() */ +PRIVATE double init_temp; /* temperature in last call to scale_pf_params */ +#define ISOLATED 256.0 + +/*-----------------------------------------------------------------*/ +static short *S, *S1; +PUBLIC int pfl_fold(char *sequence, int winSize, float cutoff, struct plist **pl) +{ + + int n, m,i,j,k,l, u,u1,ii, type, type_2, tt, ov=0; + FLT_OR_DBL temp, Qmax=0, prm_MLb; + FLT_OR_DBL prmt,prmt1; + FLT_OR_DBL qbt1, *tmp; + + double free_energy; + double max_real; + + max_real = (sizeof(FLT_OR_DBL) == sizeof(float)) ? FLT_MAX : DBL_MAX; + + n = (int) strlen(sequence); + if (ninit_length) init_pf_foldLP(n); /* (re)allocate space */ + if ((init_temp - temperature)>1e-6) update_pf_paramsLP(n); + + S = (short *) xrealloc(S, sizeof(short)*(n+1)); + S1= (short *) xrealloc(S1, sizeof(short)*(n+1)); + S[0] = n; + for (l=1; l<=n; l++) { + S[l] = (short) encode_char(toupper(sequence[l-1])); + S1[l] = alias[S[l]]; + } + /* make_ptypes(S, structure); das machmadochlieber lokal, ey!*/ + + /*array initialization ; qb,qm,q + qb,qm,q (i,j) are stored as ((n+1-i)*(n-i) div 2 + n+1-j */ + num_p=0; + *pl=space(1000*sizeof(struct plist)); + + + /* for (i=1; i<=n; i++) + qq[i]=qq1[i]=qqm[i]=qqm1[i]=prm_l[i]=prm_l1[i]=prml[i]=0; oisa gaunza unnedig, wenn nicht recycelt*/ + /*ALWAYS q[i][j] => i>j!!*/ + for (j=1; j=MAX(1,(j-winSize+1)); i--) { + /* construction of partition function of segment i,j*/ + /*firstly that given i bound to j : qb(i,j) */ + u = j-i-1; + type = ptype[i][j]; + if (type!=0) { + /*hairpin contribution*/ + if (((type==3)||(type==4))&&no_closingGU) qbt1 = 0; + else + qbt1 = expHairpinEnergy(u, type, S1[i+1], S1[j-1], sequence+i-1); + + /* interior loops with interior pair k,l */ + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); l1) qbt1 *= expdangle5[type][S1[i-1]];/*wann dangle??*/ + if (j2) qbt1 *= expTermAU; + qqm[i] += qbt1; + } + if (qm1) qm1[jindx[j]+i] = qqm[i]; /* for stochastic backtracking */ + + /*construction of qm matrix containing multiple loop + partition function contributions from segment i,j */ + temp = 0.0; + /*ii = iindx[i]; ii-k=[i,k-1] */ + for (k=i+1; k<=j; k++) temp += (qm[i][k-1]+expMLbase[k-i])*qqm[k]; + qm[i][j] = (temp + qqm[i]); + + /*auxiliary matrix qq for cubic order q calculation below */ + qbt1 = qb[i][j]; + if (type) { + if (i>1/*MAX(1,j-winSize+1)*/) qbt1 *= expdangle5[type][S1[i-1]]; + if (j2) qbt1 *= expTermAU; + } + qq[i] = qq1[i]*scale[1] + qbt1; + + /*construction of partition function for segment i,j */ + temp = 1.0*scale[1+j-i] + qq[i]; + for (k=i; k<=j-1; k++) temp += q[i][k]*qq[k+1]; + q[i][j] = temp; + + if (temp>Qmax) { + Qmax = temp; + if (Qmax>max_real/10.) + fprintf(stderr, "Q close to overflow: %d %d %g\n", i,j,temp); + } + if (temp>=max_real) { + PRIVATE char msg[128]; + sprintf(msg, "overflow in pf_fold while calculating q[%d,%d]\n" + "use larger pf_scale", i,j); + nrerror(msg); + } + } /*end for i??*/ + tmp = qq1; qq1 =qq; qq =tmp; + tmp = qqm1; qqm1=qqm; qqm=tmp; + } + +#if 0 /* no output in library functions! */ + + if ((j>winSize)&&(j<=n)) { + /*Ausgabe von freenergy fenster*/ + int middle=j-winSize/2; + double Fwind; + Fwind=(-log(q[j-winSize+1][j])-winSize*log(pf_scale))*(temperature+K0)*GASCONST/1000.0; + printf("%6d\t%.7f\n",middle, Fwind); + } +#endif + if (j>winSize) { + Qmax=0; + /*i=j-winSize;*/ + /*initialize multiloopfs*/ + for (k=j-winSize+1; k<=MIN(n,j); k++) { + prml[k]=0; + prm_l[k]=0; + /* prm_l1[k]=0; others stay??*/ + } + k=j-winSize; + for (l=k+TURN+1; l<=MIN(n,k+winSize-1); l++) { + int a; + pR[k][l] = 0; /*set zero at start*/ + type=ptype[k][l]; + if (qb[k][l]==0) continue; + + for (a=MAX(1,l-winSize+2); a=1) /*l outermost*/ + pR[k][l]+=q[l-winSize+1][k-1]/q[l-winSize+1][l]; + } + if (k>1) + pR[k][l]*=expdangle5[type][S1[k-1]]; + if (l2) + pR[k][l] *= expTermAU; + + + /*initialize multiloopfs*/ + prml[j-winSize]=0; + prm_l[j-winSize]=0; + prm_l1[j-winSize]=0; + + /* pr = q; */ /* recycling */ + + type_2 = ptype[k][l]; type_2 = rtype[type_2]; + + for (i=MAX(MAX(l-winSize+1,k-MAXLOOP-1),1); i<=k-1; i++) { + for (m=l+1; m<=MIN(MIN(l+ MAXLOOP -k+i+2,i+winSize-1),n); m++) { + type = ptype[i][m]; + if ((pR[i][m]>0)) + pR[k][l] += pR[i][m]*expLoopEnergy(k-i-1, m-l-1, type, type_2, + S1[i+1], S1[m-1], S1[k-1], S1[l+1]); + } + } + } + /* 3. bonding k,l as substem of multi-loop enclosed by i,m */ + prm_MLb = 0.; + if(k>1) /*sonst nix!*/ + for (l=MIN(n-1,k+winSize-2/*??*/); l>=k+TURN+1; l--) { /*opposite direction*/ + m=l+1; + prmt = prmt1 = 0.0; + tt = ptype[k-1][m]; tt=rtype[tt]; + prmt1 = pR[k-1][m]*expMLclosing*expMLintern[tt]* + expdangle3[tt][S1[k]]*expdangle5[tt][S1[l]]; + for (i=MAX(1,l-winSize+2/*?*/); i=l+2; m--) + temp += prml[m]*qm[l+1][m-1]; + + temp *= expMLintern[tt]*scale[2]; + if (k>1) temp *= expdangle5[tt][S1[k-1]]; + if (lQmax) { + Qmax = pR[k][l]; + if (Qmax>max_real/10.) + fprintf(stderr, "P close to overflow: %d %d %g %g\n", + i, m, pR[k][l], qb[k][l]); + } + if (pR[k][l]>=max_real) { + ov++; + pR[k][l]=FLT_MAX; + } + + } /* end for (k=..) */ + tmp = prm_l1; prm_l1=prm_l; prm_l=tmp; + + /* end for (l=..) */ + + if (j-2*winSize>0) { + printpbar(pR,winSize,j-2*winSize,n,cutoff); + *pl=get_plistW(*pl, n, cutoff, j-2*winSize, pR, winSize); + FreeOldArrays(j-2*winSize); + } + + } /* end if (do_backtrack)*/ + + + }/*end for j */ + + /*finish output and free*/ + for (j=n-winSize+1; j<=n; j++) { + printpbar(pR,winSize,j,n,cutoff); + *pl=get_plistW(*pl, n, cutoff, j, pR, winSize); + FreeOldArrays(j); + } + if (ov>0) fprintf(stderr, "%d overflows occurred while backtracking;\n" + "you might try a smaller pf_scale than %g\n", + ov, pf_scale); + + return 1; +} + +/*------------------------------------------------------------------------*/ +/* dangling ends should never be destabilizing, i.e. expdangle>=1 */ +/* specific heat needs smooth function (2nd derivative) */ +/* we use a*(sin(x+b)+1)^2, with a=2/(3*sqrt(3)), b=Pi/6-sqrt(3)/2, */ +/* in the interval b0.8660254)?(X): \ + SCALE*0.38490018*(sin((X)/SCALE-0.34242663)+1)*(sin((X)/SCALE-0.34242663)+1)) +/*#define SMOOTH(X) ((X)<0 ? 0 : (X)) */ + +PRIVATE void scale_pf_params(unsigned int length) +{ + /* scale energy parameters and pre-calculate Boltzmann weights */ + unsigned int i, j, k, l; + double kT, TT; + double GT; + + + init_temp = temperature; + kT = (temperature+K0)*GASCONST; /* kT in cal/mol */ + TT = (temperature+K0)/(Tmeasure); + + /* scaling factors (to avoid overflows) */ + if (pf_scale==-1) { /* mean energy for random sequences: 184.3*length cal */ + pf_scale = exp(-(-185+(temperature-37.)*7.27)/kT); + } + if (pf_scale<1) pf_scale=1; + scale[0] = 1.; + for (i=1; i<=length; i++) + scale[i] = scale[i-1]/pf_scale; + + /* loop energies: hairpins, bulges, interior, mulit-loops */ + for (i=0; i<=MIN(30,length); i++) { + GT = hairpin37[i]*TT; + exphairpin[i] = exp( -GT*10./kT); + } + for (i=0; i<=MIN(30, MAXLOOP); i++) { + GT = bulge37[i]*TT; + expbulge[i] = exp( -GT*10./kT); + GT = internal_loop37[i]*TT; + expinternal[i] = exp( -GT*10./kT); + } + /* special case of size 2 interior loops (single mismatch) */ + if (james_rule) expinternal[2] = exp ( -80*10/kT); + + lxc = lxc37*TT; + for (i=31; i2) GT += TerminalAU; */ + expMLintern[i] = exp( -GT*10./kT); + } + expTermAU = exp(-TerminalAU*10/kT); + + GT = ML_BASE37*TT; + for (i=0; i 0 (at large temps), + but make sure go smoothly to 0 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=4; j++) { + if (dangles) { + GT = dangle5_H[i][j] - (dangle5_H[i][j] - dangle5_37[i][j])*TT; + expdangle5[i][j] = exp(SMOOTH(-GT)*10./kT); + GT = dangle3_H[i][j] - (dangle3_H[i][j] - dangle3_37[i][j])*TT; + expdangle3[i][j] = exp(SMOOTH(-GT)*10./kT); + } else + expdangle3[i][j] = expdangle5[i][j] = 1; + if (i>2) /* add TermAU penalty into dangle3 */ + expdangle3[i][j] *= expTermAU; + } + + /* stacking energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) { + GT = enthalpies[i][j] - (enthalpies[i][j] - stack37[i][j])*TT; + expstack[i][j] = exp( -GT*10/kT); + } + + /* mismatch energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) + for (k=0; k<5; k++) { + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchI37[i][j][k])*TT; + expmismatchI[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchH37[i][j][k])*TT; + expmismatchH[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchM37[i][j][k])*TT; + expmismatchM[i][j][k] = exp(-GT*10.0/kT); + } + + /* interior lops of length 2 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + GT = int11_H[i][j][k][l] - + (int11_H[i][j][k][l] - int11_37[i][j][k][l])*TT; + expint11[i][j][k][l] = exp(-GT*10./kT); + } + /* interior 2x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m; + for (m=0; m<5; m++) { + GT = int21_H[i][j][k][l][m] - + (int21_H[i][j][k][l][m] - int21_37[i][j][k][l][m])*TT; + expint21[i][j][k][l][m] = exp(-GT*10./kT); + } + } + /* interior 2x2 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m,n; + for (m=0; m<5; m++) + for (n=0; n<5; n++) { + GT = int22_H[i][j][k][l][m][n] - + (int22_H[i][j][k][l][m][n]-int22_37[i][j][k][l][m][n])*TT; + expint22[i][j][k][l][m][n] = exp(-GT*10./kT); + } + } +} + +/*----------------------------------------------------------------------*/ +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string) { + double q; + q = exphairpin[u]; + if ((tetra_loop)&&(u==4)) { + char tl[7]={0}, *ts; + strncpy(tl, string, 6); + if ((ts=strstr(Tetraloops, tl))) + q *= exptetra[(ts-Tetraloops)/7]; + } + if (u==3) { + char tl[6]={0}, *ts; + strncpy(tl, string, 5); + if ((ts=strstr(Triloops, tl))) + q *= expTriloop[(ts-Triloops)/6]; + if (type>2) + q *= expTermAU; + } + else /* no mismatches for tri-loops */ + q *= expmismatchH[type][si1][sj1]; + + q *= scale[u+2]; + return q; +} + +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1) { + double z=0; + int no_close = 0; + + if ((no_closingGU) && ((type2==3)||(type2==4)||(type==2)||(type==4))) + no_close = 1; + + if ((u1==0) && (u2==0)) /* stack */ + z = expstack[type][type2]; + else if (no_close==0) { + if ((u1==0)||(u2==0)) { /* bulge */ + int u; + u = (u1==0)?u2:u1; + z = expbulge[u]; + if (u2+u1==1) z *= expstack[type][type2]; + else { + if (type>2) z *= expTermAU; + if (type2>2) z *= expTermAU; + } + } + else { /* interior loop */ + if (u1+u2==2) /* size 2 is special */ + z = expint11[type][type2][si1][sj1]; + else if ((u1==1) && (u2==2)) + z = expint21[type][type2][si1][sq1][sj1]; + else if ((u1==2) && (u2==1)) + z = expint21[type2][type][sq1][si1][sp1]; + else if ((u1==2) && (u2==2)) + z = expint22[type][type2][si1][sp1][sq1][sj1]; + else { + z = expinternal[u1+u2]* + expmismatchI[type][si1][sj1]* + expmismatchI[type2][sq1][sp1]; + z *= expninio[2][abs(u1-u2)]; + } + } + } + return z*scale[u1+u2+2]; +} + +/*----------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int length) +{/*arrays in 2 dimensions*/ + + q = (FLT_OR_DBL **) space((length+1)*sizeof(FLT_OR_DBL *)); + qb = (FLT_OR_DBL **) space((length+1)*sizeof(FLT_OR_DBL *)); + qm = (FLT_OR_DBL **) space((length+1)*sizeof(FLT_OR_DBL *)); + pR = (FLT_OR_DBL **) space((length+1)*sizeof(FLT_OR_DBL *)); + ptype = (char **) space((length+1)*sizeof(char *)); + /* if (st_back) { + qm1 = (FLT_OR_DBL *) space(size); + }*/ + /*length??*/ + q1k = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + qln = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l1 =(FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prml = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + exphairpin = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + expMLbase = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + scale = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + iindx = (int *) space(sizeof(int)*(length+1)); + jindx = (int *) space(sizeof(int)*(length+1)); + /* for (i=1; i<=length; i++) { + iindx[i] = ((length+1-i)*(length-i))/2 +length+1; + jindx[i] = (i*(i-1))/2; + }*/ +} + +/*----------------------------------------------------------------------*/ + +PUBLIC void init_pf_foldLP(int length) +{ + if (length<1) nrerror("init_pf_fold: length must be greater 0"); + if (init_length>0) free_pf_arraysLP(); /* free previous allocation */ +#ifdef SUN4 + nonstandard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(1); +#endif +#endif + make_pair_matrix(); + get_arrays((unsigned) length); + scale_pf_params((unsigned) length); + init_length=length; +} + +PUBLIC void free_pf_arraysLP(void) +{ + free(q); + free(qb); + free(qm); + free(pR); + q=pR=NULL; + if (qm1 != NULL) {free(qm1); qm1 = NULL;} + free(ptype); + free(qq); free(qq1); + free(qqm); free(qqm1); + free(q1k); free(qln); + free(prm_l); free(prm_l1); free(prml); + free(exphairpin); + free(expMLbase); + free(scale); + free(iindx); free(jindx); +#ifdef SUN4 + standard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(0); +#endif +#endif + init_length=0; + free(S); S=NULL; + free(S1); S1=NULL; +} +/*---------------------------------------------------------------------------*/ + +PUBLIC void update_pf_paramsLP(int length) +{ + if (length>init_length) init_pf_foldLP(length); /* init not update */ + else { + /* make_pair_matrix();*/ + scale_pf_params((unsigned) length); + } +} + +/*---------------------------------------------------------------------------*/ + + +PRIVATE void printpbar(FLT_OR_DBL **prb,int winSize, int i, int n, float cutoff) { + int j; + int howoften=0; /* how many samples do we have for this pair */ + int pairdist; + + for (j=i+TURN; jtQ5*#2h0fM3+%u0}O3kerZfRzkRU;+WTBq1OWl1T#5kc3GHs1Sk) z=okX1>@Etrtm}F~U43_5MMVi95WFoQD(bG{JrNbeRS}i^tGcVs>GWjw)qUUZ|2*IG zd<~gX{X5mwRn^s(bNZZ_RcRR$>^7Uh$!1(>SUE-w<5b9^Qw5o7^f7uF{@Tx7^*s<+ zbELXks{8o^4bvJ!hy1lKxb_wm6>S9MyIpv?89$Pa_}4W0L%S>g*${>K(2E22BsJEa 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znfTw-_!~)|4>kU6#Q(X*e-F(sXEgo?iN7=5cVRz2PI!L}-$D2T(j5l!lc@rs+W}$@ z_Yn^sJVfjKV+qGNQTbCf{sojTprg*eNaN@Iz7-MpYc&3Cs2HTJ@(`x~Ho{qd-p4r_ zfuHZQGC%KAsLwN~_Tu;WV`Bb9YOhSfb$fF(e!hRp^MKC3T;u2avH1P+m~{TfHGaN- z_(BB!CXJu(`+XjP|CGkh_v<`D8_N%rHBvQv0p%mLdyU4=?Ym9Gxg8_5SEP1{>d9I4w8KxIzrm{|CbhBW3^q literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/Lfold.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/Lfold.c new file mode 100755 index 00000000..142a5736 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/Lfold.c @@ -0,0 +1,856 @@ +/* Last changed Time-stamp: <2005-10-30 21:03:40 ivo> */ +/* + minimum free energy + RNA secondary structure prediction + with maximum distance base pairs + + c Ivo Hofacker, Peter Stadler + + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "params.h" + +/*@unused@*/ +static char rcsid[] UNUSED = "$Id: Lfold.c,v 1.5 2005/10/30 20:06:20 ivo Exp $"; + + +#define PAREN + +#define PUBLIC +#define PRIVATE static + +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define NEW_NINIO 1 /* new asymetry penalty */ + +PUBLIC float Lfold(char *string, char *structure, int maxdist); +PRIVATE void initialize_fold(int length, int maxdist); +PRIVATE void update_fold_params(void); + +/*@unused@*/ +PRIVATE void letter_structure(char *structure, int length) UNUSED; +/* PRIVATE void parenthesis_structure(char *structure, int length); */ +PRIVATE void get_arrays(unsigned int size, int maxdist); +PRIVATE void free_arrays(int maxdist); +/* PRIVATE void scale_parameters(void); */ +/* PRIVATE int stack_energy(int i, char *string); + PRIVATE int ML_Energy(int i, int is_extloop); */ +PRIVATE void make_ptypes(const short *S, int i, int maxdist, int n); +PRIVATE void encode_seq(char *sequence); +PRIVATE char * backtrack(char *sequence, int start, int maxdist); +PRIVATE int fill_arrays(char *sequence, int maxdist); +extern int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1); +extern int HairpinE(int size, int type, int si1, int sj1, const char *string); + +/*@unused@*/ +#define MAXSECTORS 500 /* dimension for a backtrack array */ +#define LOCALITY 0. /* locality parameter for base-pairs */ + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) +#define SAME_STRAND(I,J) (((I)>=cut_point)||((J)(int)size-maxdist-5 && i>=0; i--) { + c[i] = (int *) space(sizeof(int)*(maxdist+5)); + } + for (i=size; i>(int)size-maxdist-5 && i>=0; i--) { + fML[i] = (int *) space(sizeof(int)*(maxdist+5)); + } + for (i=size; i>(int)size-maxdist-5 && i>=0; i--) { + ptype[i] = (char *) space(sizeof(char)*(maxdist+5)); + } +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void free_arrays(int maxdist) +{ + int i; + for (i=0; i = base must be paired with j>i + -4: x = base must not pair + positive int: base is paired with int */ + +float Lfold(char *string, char *structure, int maxdist) { + int i, energy, bonus=0; + + length = (int) strlen(string); + if (maxdist>length) maxdist = length; + initialize_fold(length, maxdist); + if (fabs(P->temperature - temperature)>1e-6) update_fold_params(); + + encode_seq(string); + + /* BP = (int *)space(sizeof(int)*(length+2)); */ + for (i=length; i>(int)length-(int)maxdist-4 && i>0; i--) + make_ptypes(S, i, maxdist, length); + + energy = fill_arrays(string, maxdist); + + /* parenthesis_structure(structure, length); */ + + free(S); free(S1);\ + + energy += bonus; /*remove bonus energies from result */ + free_arrays(maxdist); + return (float) energy/100.; +} + +PRIVATE int fill_arrays(char *string, int maxdist) { + /* fill "c", "fML" and "f3" arrays and return optimal energy */ + + int i, j, k, length, energy; + int decomp, new_fML; + int no_close, type, type_2, tt; + int bonus=0; + + length = (int) strlen(string); + + for (j=0; jlength-maxdist-4; j--) { + for (i=(length-maxdist-4>0)?length-maxdist-4:1 ; i= 1; i--) { /* i,j in [1..length] */ + + for (j = i+TURN+1; j <= length && j <= i+maxdist; j++) { + int p, q; + bonus = 0; + type = ptype[i][j-i]; + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + + if (type) { /* we have a pair */ + int new_c=0, stackEnergy=INF; + /* hairpin ----------------------------------------------*/ + + if (no_close) new_c = FORBIDDEN; + else + new_c = HairpinE(j-i-1, type, S1[i+1], S1[j-1], string+i-1); + + /*-------------------------------------------------------- + check for elementary structures involving more than one + closing pair. + --------------------------------------------------------*/ + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1) ; p++) { + int minq = j-i+p-MAXLOOP-2; + if (minqi+1)||(qdangle3[tt][S1[i+1]]; + d5 = P->dangle5[tt][S1[j-1]]; + if (dangles==2) /* double dangles */ + decomp += d5 + d3; + else { /* normal dangles */ + decomp = MIN2(DMLi2[j-1-(i+2)]+d3+P->MLbase, decomp); + decomp = MIN2(DMLi1[j-2-(i+1)]+d5+P->MLbase, decomp); + decomp = MIN2(DMLi2[j-2-(i+2)]+d5+d3+2*P->MLbase, decomp); + } + } + + MLenergy = P->MLclosing+P->MLintern[type]+decomp; + + new_c = MLenergy < new_c ? MLenergy : new_c; + } + + /* coaxial stacking of (i.j) with (i+1.k) or (k+1.j-1) */ + + if (dangles==3) { + decomp = INF; + for (k = i+2+TURN; k < j-2-TURN; k++) { + type_2 = ptype[i+1][k-i-1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[i+1][k-i-1]+P->stack[type][type_2]+ + fML[k+1][j-1-k-1]); + type_2 = ptype[k+1][j-1-k-1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[k+1][j-1-k-1]+P->stack[type][type_2]+ + fML[i+1][k-i-1]); + } + /* no TermAU penalty if coax stack */ + decomp += 2*P->MLintern[1] + P->MLclosing; + new_c = MIN2(new_c, decomp); + } + + new_c = MIN2(new_c, cc1[j-1-(i+1)]+stackEnergy); + cc[j-i] = new_c + bonus; + if (noLonelyPairs) + c[i][j-i] = cc1[j-1-(i+1)]+stackEnergy+bonus; + else + c[i][j-i] = cc[j-i]; + + } /* end >> if (pair) << */ + + else c[i][j-i] = INF; + + + /* done with c[i,j], now compute fML[i,j] */ + /* free ends ? -----------------------------------------*/ + + new_fML = fML[i+1][j-i-1]+P->MLbase; + new_fML = MIN2(fML[i][j-1-i]+P->MLbase, new_fML); + energy = c[i][j-i]+P->MLintern[type]; + if (dangles==2) { /* double dangles */ + if (i>1) energy += P->dangle5[type][S1[i-1]]; + if (jdangle3[type][S1[j+1]]; + } + new_fML = MIN2(energy, new_fML); + + if (dangles%2==1) { /* normal dangles */ + tt = ptype[i+1][j-i-1]; /* i+1,j */ + new_fML = MIN2(c[i+1][j-i-1]+P->dangle5[tt][S1[i]] + +P->MLintern[tt]+P->MLbase,new_fML); + tt = ptype[i][j-1-i]; + new_fML = MIN2(c[i][j-1-i]+P->dangle3[tt][S1[j]] + +P->MLintern[tt]+P->MLbase, new_fML); + tt = ptype[i+1][j-1-i-1]; + new_fML = MIN2(c[i+1][j-1-i-1]+P->dangle5[tt][S1[i]]+ + P->dangle3[tt][S1[j]]+P->MLintern[tt]+2*P->MLbase, new_fML); + } + + /* modular decomposition -------------------------------*/ + + for (decomp = INF, k = i+1+TURN; k <= j-2-TURN; k++) + decomp = MIN2(decomp, Fmi[k-i]+fML[k+1][j-k-1]); + + DMLi[j-i] = decomp; /* store for use in ML decompositon */ + new_fML = MIN2(new_fML,decomp); + + /* coaxial stacking */ + if (dangles==3) { + /* additional ML decomposition as two coaxially stacked helices */ + for (decomp = INF, k = i+1+TURN; k <= j-2-TURN; k++) { + type = ptype[i][k-i]; type = rtype[type]; + type_2 = ptype[k+1][j-k-1]; type_2 = rtype[type_2]; + if (type && type_2) + decomp = MIN2(decomp, + c[i][k-i]+c[k+1][j-k-1]+P->stack[type][type_2]); + } + + decomp += 2*P->MLintern[1]; /* no TermAU penalty if coax stack */ +#if 0 + /* This is needed for Y shaped ML loops with coax stacking of + interior pairts, but backtracking will fail if activated */ + DMLi[j-i] = MIN2(DMLi[j-i], decomp); + DMLi[j-i] = MIN2(DMLi[j-i], DMLi[j-1-i]+P->MLbase); + DMLi[j-i] = MIN2(DMLi[j-i], DMLi1[j-(i+1)]+P->MLbase); + new_fML = MIN2(new_fML, DMLi[j-i]); +#endif + new_fML = MIN2(new_fML, decomp); + } + + fML[i][j-i] = Fmi[j-i] = new_fML; /* substring energy */ + + } /* for (j...) */ + + /* calculate energies of 5' and 3' fragments */ + { + static int do_backtrack = 0, prev_i=0; + static char * prev=NULL; + char *ss; + f3[i] = f3[i+1]; + for (j=i+TURN+1; j2) energy += P->TerminalAU; + if (dangles==2) { + if (i>1) energy += P->dangle5[type][S1[i-1]]; + energy += P->dangle3[type][S1[j+1]]; + } + f3[i] = MIN2(f3[i], energy); + if (dangles%2==1) { + energy = c[i][j-i]+P->dangle3[type][S1[j+1]]; + if (j+2<=length) energy += f3[j+2]; + if (type>2) energy += P->TerminalAU; + f3[i] = MIN2(f3[i], energy); + } + } + type = ptype[i+1][j-i-1]; + if ((type)&&(dangles%2==1)) { + energy = c[i+1][j-i-1]+P->dangle5[type][S1[i]]; + if (type>2) energy += P->TerminalAU; + f3[i] = MIN2(f3[i], f3[j+1]+energy); + energy+=P->dangle3[type][S1[j+1]]; + if (j+12) energy += P->TerminalAU; + if (dangles==2) { + energy += P->dangle5[type][S1[i-1]]; + } + f3[i] = MIN2(f3[i], energy); + } + type = ptype[i+1][j-i-1]; + if ((type)&&(dangles%2==1)) { + energy = c[i+1][j-i-1]+P->dangle5[type][S1[i]]; + if (type>2) energy += P->TerminalAU; + f3[i] = MIN2(f3[i], energy); + } + } + /* backtrack partial structure */ + if (f3[i] != f3[i+1]) do_backtrack=1; + else if (do_backtrack) { + ss = backtrack(string, i+1 , maxdist+1); + if (prev) { + if ((i+strlen(ss)1) make_ptypes(S, i-1, maxdist, length); + for (ii=0; ii0) { + int ml, fij, cij, traced, i1, j1, d3, d5, mm, p, q, jj=0; + int canonical = 1; /* (i,j) closes a canonical structure */ + i = sector[s].i; + j = sector[s].j; + ml = sector[s--].ml; /* ml is a flag indicating if backtracking is to + occur in the fML- (1) or in the f-array (0) */ + if (ml==2) { + structure[i-start] = '('; + structure[j-start] = ')'; + goto repeat1; + } + + if (j < i+TURN+1) continue; /* no more pairs in this interval */ + + fij = (ml)? fML[i][j-i] : f3[i]; + + if (ml == 0) { /* backtrack in f3 */ + + if (fij == f3[i+1]) { + sector[++s].i = i+1; + sector[s].j = j; + sector[s].ml = ml; + continue; + } + /* i or i+1 is paired. Find pairing partner */ + for (k=i+TURN+1,traced=0; k<=j; k++) { + int cc, en; + jj = k+1; + type = ptype[i+1][k-(i+1)]; + if((type)&&(dangles%2==1)) { + cc = c[i+1][k-(i+1)]+P->dangle5[type][S1[i]]; + if (type>2) cc += P->TerminalAU; + if (fij == cc + f3[k+1]) + traced=i+1; + if (kdangle3[type][S1[k+1]]) { + traced=i+1; jj=k+2; + } + } + type = ptype[i][k-i]; + if (type) { + cc = c[i][k-i]; + if (type>2) cc += P->TerminalAU; + en = cc + f3[k+1]; + if (dangles==2) { + if (i>1) en += P->dangle5[type][S1[i-1]]; + if (kdangle3[type][S1[k+1]]; + } + if (fij == en) traced=i; + if ((dangles%2==1) && (kdangle3[type][S1[k+1]]) { + traced=i; jj=k+2; + } + } + if (traced) break; + } + + if (!traced) nrerror("backtrack failed in f3"); + if (j==length) { /* backtrack only one component, unless j==length */ + sector[++s].i = jj; + sector[s].j = j; + sector[s].ml = ml; + } + i=traced; j=k; + structure[i-start] = '('; structure[j-start] = ')'; + if ((jj==j+2) || (dangles==2)) structure[j+1-start] = '.'; + goto repeat1; + } + else { /* trace back in fML array */ + int cij1=INF, ci1j=INF, ci1j1=INF; + + if (fML[i][j-1-i]+P->MLbase == fij) { /* 3' end is unpaired */ + sector[++s].i = i; + sector[s].j = j-1; + sector[s].ml = ml; + continue; + } + if (fML[i+1][j-(i+1)]+P->MLbase == fij) { /* 5' end is unpaired */ + sector[++s].i = i+1; + sector[s].j = j; + sector[s].ml = ml; + continue; + } + + tt = ptype[i][j-i]; + cij = c[i][j-i] + P->MLintern[tt]; + if (dangles==2) { /* double dangles */ + if (i>1) cij += P->dangle5[tt][S1[i-1]]; + if (jdangle3[tt][S1[j+1]]; + } + else if (dangles%2==1) { /* normal dangles */ + tt = ptype[i+1][j-(i+1)]; + ci1j= c[i+1][j-(i+1)] + P->dangle5[tt][S1[i]] + P->MLintern[tt]+P->MLbase; + tt = ptype[i][j-1-i]; + cij1= c[i][j-1-i] + P->dangle3[tt][S1[j]] + P->MLintern[tt]+P->MLbase; + tt = ptype[i+1][j-1-(i+1)]; + ci1j1=c[i+1][j-1-(i+1)] + P->dangle5[tt][S1[i]] + P->dangle3[tt][S1[j]] + + P->MLintern[tt] + 2*P->MLbase; + } + + if ((fij==cij)||(fij==ci1j)||(fij==cij1)||(fij==ci1j1)) { + /* found a pair */ + if (fij==ci1j) i++; + else if (fij==cij1) j--; + else if (fij==ci1j1) {i++; j--;} + structure[i-start] = '('; structure[j-start] = ')'; + goto repeat1; + } + + for (k = i+1+TURN; k <= j-2-TURN; k++) + if (fij == (fML[i][k-i]+fML[k+1][j-(k+1)])) + break; + + if ((dangles==3)&&(k>j-2-TURN)) { /* must be coax stack */ + ml = 2; + for (k = i+1+TURN; k <= j-2-TURN; k++) { + type = ptype[i][k-i]; type= rtype[type]; + type_2 = ptype[k+1][j-(k+1)]; type_2= rtype[type_2]; + if (type && type_2) + if (fij == c[i][k-i]+c[k+1][j-(k+1)]+P->stack[type][type_2]+ + 2*P->MLintern[1]) + break; + } + } + + sector[++s].i = i; + sector[s].j = k; + sector[s].ml = ml; + sector[++s].i = k+1; + sector[s].j = j; + sector[s].ml = ml; + + if (k>j-2-TURN) nrerror("backtrack failed in fML"); + continue; + } + + repeat1: + + /*----- begin of "repeat:" -----*/ + if (canonical) cij = c[i][j-i]; + + type = ptype[i][j-i]; + + bonus = 0; + + if (noLonelyPairs) + if (cij == c[i][j-i]) { + /* (i.j) closes canonical structures, thus + (i+1.j-1) must be a pair */ + type_2 = ptype[i+1][j-1-(i+1)]; type_2 = rtype[type_2]; + cij -= P->stack[type][type_2] + bonus; + structure[i+1-start] = '('; structure[j-1-start] = ')'; + i++; j--; + canonical=0; + goto repeat1; + } + canonical = 1; + + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + if (no_close) { + if (cij == FORBIDDEN) continue; + } else + if (cij == HairpinE(j-i-1, type, S1[i+1], S1[j-1],string+i-1)+bonus) + continue; + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1); p++) { + int minq; + minq = j-i+p-MAXLOOP-2; + if (minq= minq; q--) { + + type_2 = ptype[p][q-p]; + if (type_2==0) continue; + type_2 = rtype[type_2]; + if (no_closingGU) + if (no_close||(type_2==3)||(type_2==4)) + if ((p>i+1)||(qMLclosing+P->MLintern[tt]; + d5 = P->dangle5[tt][S1[j-1]]; + d3 = P->dangle3[tt][S1[i+1]]; + i1 = i+1; j1 = j-1; + sector[s+1].ml = sector[s+2].ml = 1; + + for (k = i+2+TURN; k < j-2-TURN; k++) { + int en; + en = fML[i+1][k-(i+1)]+fML[k+1][j-1-(k+1)]+mm; + if (dangles==2) /* double dangles */ + en += d5+d3; + if (cij == en) + break; + if (dangles%2==1) { /* normal dangles */ + if (cij == (fML[i+2][k-(i+2)]+fML[k+1][j-1-(k+1)]+mm+d3+P->MLbase)) { + i1 = i+2; + break; + } + if (cij == (fML[i+1][k-(i+1)]+fML[k+1][j-2-(k+1)]+mm+d5+P->MLbase)) { + j1 = j-2; + break; + } + if (cij == (fML[i+2][k-(i+2)]+fML[k+1][j-2-(k+1)]+mm+d3+d5+P->MLbase+P->MLbase)) { + i1 = i+2; j1 = j-2; + break; + } + } + /* coaxial stacking of (i.j) with (i+1.k) or (k.j-1) */ + /* use MLintern[1] since coax stacked pairs don't get TerminalAU */ + if (dangles==3) { + type_2 = ptype[i+1][k-(i+1)]; type_2 = rtype[type_2]; + if (type_2) { + en = c[i+1][k-(i+1)]+P->stack[type][type_2]+fML[k+1][j-1-(k+1)]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + ml = 2; + sector[s+1].ml = 2; + break; + } + } + type_2 = ptype[k+1][j-1-(k+1)]; type_2 = rtype[type_2]; + if (type_2) { + en = c[k+1][j-1-(k+1)]+P->stack[type][type_2]+fML[i+1][k-(i+1)]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + sector[s+2].ml = 2; + break; + } + } + } + + } + if (k<=j-3-TURN) { /* found the decomposition */ + sector[++s].i = i1; + sector[s].j = k; + sector[++s].i = k+1; + sector[s].j = j1; + } else { +#if 0 + /* Y shaped ML loops fon't work yet */ + if (dangles==3) { + /* (i,j) must close a Y shaped ML loop with coax stacking */ + if (cij == fML[i+1][j-2-(i+2)] + mm + d3 + d5 + P->MLbase + P->MLbase) { + i1 = i+2; + j1 = j-2; + } else if (cij == fML[i+1][j-2-(i+1)] + mm + d5 + P->MLbase) + j1 = j-2; + else if (cij == fML[i+2][j-1-(i+2)] + mm + d3 + P->MLbase) + i1 = i+2; + else /* last chance */ + if (cij != fML[i+1][j-1-(i+1)] + mm + P->MLbase) + fprintf(stderr, "backtracking failed in repeat"); + /* if we arrive here we can express cij via fML[i1,j1]+dangles */ + sector[++s].i = i1; + sector[s].j = j1; + } + else +#endif + nrerror("backtracking failed in repeat"); + } + + } + + for (i=strlen(structure)-1; i>0 && structure[i] == '-'; i--) + structure[i] = '\0'; + for (;i>=0; i--) + if (structure[i]=='-') structure[i]='.'; + + return structure; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void encode_seq(char *sequence) { + unsigned int i,l; + + l = strlen(sequence); + S = (short *) space(sizeof(short)*(l+1)); + S1= (short *) space(sizeof(short)*(l+1)); + /* S1 exists only for the special X K and I bases and energy_set!=0 */ + S[0] = S1[0] = (short) l; + + for (i=1; i<=l; i++) { /* make numerical encoding of sequence */ + S[i]= (short) encode_char(toupper(sequence[i-1])); + S1[i] = alias[S[i]]; /* for mismatches of nostandard bases */ + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void letter_structure(char *structure, int length) +{ + int n, k, x, y; + + for (n = 0; n <= length-1; structure[n++] = ' ') ; + structure[length] = '\0'; + + for (n = 0, k = 1; k <= base_pair[0].i; k++) { + y = base_pair[k].j; + x = base_pair[k].i; + if (x-1 > 0 && y+1 <= length) { + if (structure[x-2] != ' ' && structure[y] == structure[x-2]) { + structure[x-1] = structure[x-2]; + structure[y-1] = structure[x-1]; + continue; + } + } + if (structure[x] != ' ' && structure[y-2] == structure[x]) { + structure[x-1] = structure[x]; + structure[y-1] = structure[x-1]; + continue; + } + n++; + structure[x-1] = alpha[n-1]; + structure[y-1] = alpha[n-1]; + } +} + +/*---------------------------------------------------------------------------*/ +#if 0 +PRIVATE void parenthesis_structure(char *structure, int length) +{ + int n, k; + + for (n = 0; n <= length-1; structure[n++] = '.') ; + structure[length] = '\0'; + + for (k = 1; k <= base_pair[0].i; k++) { + structure[base_pair[k].i-1] = '('; + structure[base_pair[k].j-1] = ')'; + } +} +#endif +/*---------------------------------------------------------------------------*/ + +PRIVATE void update_fold_params(void) +{ + P = scale_parameters(); + make_pair_matrix(); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void make_ptypes(const short *S, int i, int maxdist, int n) { + int j,k, type; + + for (k=TURN+1; kn) continue; + type = pair[S[i]][S[j]]; + if (noLonelyPairs && type) { + if (!ptype[i+1][j-1-i-1]) + if (j==n || i==1 || (!pair[S[i-1]][S[j+1]])) type=0; + } + ptype[i][j-i]=type; + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/Lfold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/Lfold.o new file mode 100755 index 0000000000000000000000000000000000000000..e6ee3f70cfc4d8eda9d7ee2cfd59a9d20ed4a59c GIT binary patch literal 55696 zcmeIbdw5hu@;82F&ICq?nE(+1QKCfT8VCXsKxJS869^i}#UPOoCIO-$gj@tPhDZ{Y zaR`EoD=O}~F1sqLySnQI6*b)Pj);Q0>x!3kiI)Yuq5|`)>aOb3bP{*>`+MH+^ZxOk z2j*0NPIYy4RdscrK4&J&(=sNxT`r3cmvx2Zlo++F_$G%QFUav$qIJF%tpD5_IR}Bp z{k2`k`(D`7l-V5K7p&ju-7#<8ytROQ_aa_Cf*&dSgN@C>@V2V=nqsgVetE$5l;-*$ 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+ +#define PUBLIC +#define PRIVATE static +#define MAX(A,B) (A)>(B)?(A):(B) +#ifndef PI +#define PI 3.141592654 +#endif +#define PIHALF PI/2. + +PUBLIC int gmlRNA(char *string, char *structure, char *ssfile, char option); +PUBLIC int PS_rna_plot_a(char *string, char *structure, char *ssfile, + char *pre, char *post); +PUBLIC int PS_rna_plot(char *string, char *structure, char *ssfile); +PUBLIC int ssv_rna_plot(char *string, char *structure, char *ssfile); +PUBLIC int xrna_plot(char *string, char *structure, char *ssfile); + +PUBLIC int simple_xy_coordinates(short *pair_table, float *X, float *Y); +extern int naview_xy_coordinates(short *pair_table, float *X, float *Y); + +PUBLIC int rna_plot_type = 1; /* 0 = simple, 1 = naview */ + +PUBLIC int PS_dot_plot(char *string, char *wastlfile); +PUBLIC int PS_color_dot_plot(char *seq, cpair *pi, char *wastlfile); +PUBLIC int PS_dot_plot_list(char *string, char *wastlfile, struct plist *pl, + struct plist *mf, char *comment); +PUBLIC int PS_dot_plot_turn(char *seq, struct plist *pl, char *wastlfile, + int winSize); + +/* local functions */ +PRIVATE void loop(int i, int j, short *pair_table); +PRIVATE FILE *PS_dot_common(char *seq, char *wastlfile, char *comment, + int winsize); + +/* local variables for parsing routines */ +PRIVATE float *angle; +PRIVATE int *loop_size, *stack_size; +PRIVATE int lp, stk; + +extern int cut_point; /* set to first pos of second seq for cofolding */ + +/*---------------------------------------------------------------------------*/ + +/* options for gml output: + uppercase letters: print sequence labels + lowercase letters: no sequence lables + graphics information: + x X simple xy plot + (nothing else implemented at present) + default: no graphics data at all +*/ + +PUBLIC int gmlRNA(char *string, char *structure, char *ssfile, char option) +{ + FILE *gmlfile; + int i; + int length; + int labels=0; + short *pair_table; + float *X, *Y; + + if (isupper(option)) labels = 1; + + gmlfile = fopen(ssfile, "w"); + if (gmlfile == NULL) { + fprintf(stderr, "can't open file %s - not doing xy_plot\n", ssfile); + return 0; + } + + length = strlen(string); + + pair_table = make_pair_table(structure); + + switch(option){ + case 'X' : + case 'x' : + /* Simple XY Plot */ + X = (float *) space((length+1)*sizeof(float)); + Y = (float *) space((length+1)*sizeof(float)); + if (rna_plot_type == 0) + i = simple_xy_coordinates(pair_table, X, Y); + else + i = naview_xy_coordinates(pair_table, X, Y); + + if(i!=length) fprintf(stderr,"strange things happening in gmlRNA ...\n"); + break; + default: + /* No Graphics Information */ + X = NULL; + Y = NULL; + } + + fprintf(gmlfile, + "# Vienna RNA Package %s\n" + "# GML Output\n" + "# CreationDate: %s\n" + "# Name: %s\n" + "# Options: %s\n", VERSION, time_stamp(), ssfile, option_string()); + fprintf(gmlfile, + "graph [\n" + " directed 0\n"); + for (i=1; i<=length; i++){ + fprintf(gmlfile, + " node [ id %d ", i); + if (option) fprintf(gmlfile, + "label \"%c\"",string[i-1]); + if ((option == 'X')||(option=='x')) + fprintf(gmlfile, + "\n graphics [ x %9.4f y %9.4f ]\n", X[i-1], Y[i-1]); + fprintf(gmlfile," ]\n"); + } + for (i=1; ii) + fprintf(gmlfile, + "edge [ source %d target %d ]\n", i, pair_table[i]); + } + fprintf(gmlfile, "]\n"); + fclose(gmlfile); + + free(pair_table); + free(X); free(Y); + return 1; /* success */ +} + +/*---------------------------------------------------------------------------*/ +int PS_rna_plot(char *string, char *structure, char *ssfile) { + return PS_rna_plot_a(string, structure, ssfile, NULL, NULL); +} + +static const char *RNAss_head = +"%%BeginProlog\n" +"/RNAplot 100 dict def\n" +"RNAplot begin\n" +"/fsize 14 def\n" +"/outlinecolor {0.2 setgray} bind def\n" +"/paircolor {0.2 setgray} bind def\n" +"/seqcolor {0 setgray} bind def\n" +"/cshow { dup stringwidth pop -2 div fsize -3 div rmoveto show} bind def\n" +"/min { 2 copy gt { exch } if pop } bind def\n" +"/max { 2 copy lt { exch } if pop } bind def\n" +"/drawoutline {\n" +" gsave outlinecolor newpath\n" +" coor 0 get aload pop 0.8 0 360 arc % draw 5' circle of 1st sequence\n" +" currentdict /cutpoint known % check if cutpoint is defined\n" +" {coor 0 cutpoint getinterval\n" +" {aload pop lineto} forall % draw outline of 1st sequence\n" +" coor cutpoint get aload pop\n" +" 2 copy moveto 0.8 0 360 arc % draw 5' circle of 2nd sequence\n" +" coor cutpoint coor length cutpoint sub getinterval\n" +" {aload pop lineto} forall} % draw outline of 2nd sequence\n" +" {coor {aload pop lineto} forall} % draw outline as a whole\n" +" ifelse\n" +" stroke grestore\n" +"} bind def\n" +"/drawpairs {\n" +" paircolor\n" +" 0.7 setlinewidth\n" +" [9 3.01] 9 setdash\n" +" newpath\n" +" pairs {aload pop\n" +" coor exch 1 sub get aload pop moveto\n" +" coor exch 1 sub get aload pop lineto\n" +" } forall\n" +" stroke\n" +"} bind def\n" +"% draw bases\n" +"/drawbases {\n" +" [] 0 setdash\n" +" seqcolor\n" +" 0\n" +" coor {\n" +" aload pop moveto\n" +" dup sequence exch 1 getinterval cshow\n" +" 1 add\n" +" } forall\n" +" pop\n" +"} bind def\n\n" +"/init {\n" +" /Helvetica findfont fsize scalefont setfont\n" +" 1 setlinejoin\n" +" 1 setlinecap\n" +" 0.8 setlinewidth\n" +" 72 216 translate\n" +" % find the coordinate range\n" +" /xmax -1000 def /xmin 10000 def\n" +" /ymax -1000 def /ymin 10000 def\n" +" coor {\n" +" aload pop\n" +" dup ymin lt {dup /ymin exch def} if\n" +" dup ymax gt {/ymax exch def} {pop} ifelse\n" +" dup xmin lt {dup /xmin exch def} if\n" +" dup xmax gt {/xmax exch def} {pop} ifelse\n" +" } forall\n" +" /size {xmax xmin sub ymax ymin sub max} bind def\n" +" 72 6 mul size div dup scale\n" +" size xmin sub xmax sub 2 div size ymin sub ymax sub 2 div\n" +" translate\n" +"} bind def\n" +"end\n"; + +static const char *anote_macros = +"RNAplot begin\n" +"% extra definitions for standard anotations\n" +"/min { 2 copy gt { exch } if pop } bind def\n" +"/BLACK { 0 0 0 } def\n" +"/RED { 1 0 0 } def\n" +"/GREEN { 0 1 0 } def\n" +"/BLUE { 0 0 1 } def\n" +"/WHITE { 1 1 1 } def\n" +"/LabelFont { % font size LabelFont\n" +" exch findfont exch fsize mul scalefont setfont\n" +"} bind def\n" +"/Label { % i dx dy (text) Label\n" +" % write text at base i plus offset dx, dy\n" +" 4 3 roll 1 sub coor exch get aload pop moveto\n" +" 3 1 roll fsize mul exch fsize mul exch rmoveto\n" +" show\n" +"} bind def\n" +"/cmark { % i cmark draw circle around base i\n" +" newpath 1 sub coor exch get aload pop\n" +" fsize 2 div 0 360 arc stroke\n" +"} bind def\n" +"/gmark { % i j c cmark\n" +" % draw basepair i,j with c counter examples in gray\n" +" gsave\n" +" 3 min [0 0.33 0.66 0.9] exch get setgray\n" +" 1 sub dup coor exch get aload pop moveto\n" +" sequence exch 1 getinterval cshow\n" +" 1 sub dup coor exch get aload pop moveto\n" +" sequence exch 1 getinterval cshow\n" +" grestore\n" +"} bind def\n" +"/segmark { % f i j lw r g b segmark\n" +" % mark segment [i,j] with outline width lw and color rgb\n" +" % use omark and Fomark instead\n" +" gsave\n" +" setrgbcolor setlinewidth\n" +" newpath\n" +" 1 sub exch 1 sub dup\n" +" coor exch get aload pop moveto\n" +" exch 1 exch {\n" +" coor exch get aload pop lineto\n" +" } for\n" +" { closepath fill } if stroke\n" +" grestore\n" +"} bind def\n" +"/omark { % i j lw r g b omark\n" +" % stroke segment [i..j] with linewidth lw, color rgb\n" +" false 7 1 roll segmark\n" +"} bind def\n" +"/Fomark { % i j r g b Fomark\n" +" % fill segment [i..j] with color rgb\n" +" % should precede drawbases\n" +" 1 4 1 roll true 7 1 roll segmark\n" +"} bind def\n" +"/BFmark{ % i j k l r g b BFmark\n" +" % fill block between pairs (i,j) and (k,l) with color rgb\n" +" % should precede drawbases\n" +" gsave\n" +" setrgbcolor\n" +" newpath\n" +" exch 4 3 roll exch 1 sub exch 1 sub dup\n" +" coor exch get aload pop moveto\n" +" exch 1 exch { coor exch get aload pop lineto } for\n" +" exch 1 sub exch 1 sub dup\n" +" coor exch get aload pop lineto\n" +" exch 1 exch { coor exch get aload pop lineto } for\n" +" closepath fill stroke\n" +" grestore\n" +"} bind def\n" +"end\n\n"; + +int PS_rna_plot_a(char *string, char *structure, char *ssfile, char *pre, char *post) +{ + float xmin, xmax, ymin, ymax, size; + int i, length; + float *X, *Y; + FILE *xyplot; + short *pair_table; + + length = strlen(string); + + xyplot = fopen(ssfile, "w"); + if (xyplot == NULL) { + fprintf(stderr, "can't open file %s - not doing xy_plot\n", ssfile); + return 0; + } + + pair_table = make_pair_table(structure); + + X = (float *) space((length+1)*sizeof(float)); + Y = (float *) space((length+1)*sizeof(float)); + if (rna_plot_type == 0) + i = simple_xy_coordinates(pair_table, X, Y); + else + i = naview_xy_coordinates(pair_table, X, Y); + if(i!=length) fprintf(stderr,"strange things happening in PS_rna_plot...\n"); + + xmin = xmax = X[0]; + ymin = ymax = Y[0]; + for (i = 1; i < length; i++) { + xmin = X[i] < xmin ? X[i] : xmin; + xmax = X[i] > xmax ? X[i] : xmax; + ymin = Y[i] < ymin ? Y[i] : ymin; + ymax = Y[i] > ymax ? Y[i] : ymax; + } + size = MAX((xmax-xmin),(ymax-ymin)); + + fprintf(xyplot, + "%%!PS-Adobe-3.0 EPSF-3.0\n" + "%%%%Creator: %s, ViennaRNA-%s\n" + "%%%%CreationDate: %s" + "%%%%Title: RNA Secondary Structure Plot\n" + "%%%%BoundingBox: 66 210 518 662\n" + "%%%%DocumentFonts: Helvetica\n" + "%%%%Pages: 1\n" + "%%%%EndComments\n\n" + "%%Options: %s\n", rcsid+5, VERSION, time_stamp(), option_string()); + fprintf(xyplot, "%% to switch off outline pairs of sequence comment or\n" + "%% delete the appropriate line near the end of the file\n\n"); + fprintf(xyplot, "%s", RNAss_head); + + if (pre || post) { + fprintf(xyplot, "%s", anote_macros); + } + fprintf(xyplot, "%%%%EndProlog\n"); + + fprintf(xyplot, "RNAplot begin\n" + "%% data start here\n"); + + /* cut_point */ + if (cut_point > 0 && cut_point <= strlen(string)) + fprintf(xyplot, "/cutpoint %d def\n", cut_point-1); + + /* sequence */ + fprintf(xyplot,"/sequence (\\\n"); + i=0; + while (ii) + fprintf(xyplot, "[%d %d]\n", i, pair_table[i]); + fprintf(xyplot, "] def\n\n"); + + fprintf(xyplot, "init\n\n"); + /* draw the data */ + if (pre) { + fprintf(xyplot, "%% Start Annotations\n"); + fprintf(xyplot, "%s\n", pre); + fprintf(xyplot, "%% End Annotations\n"); + } + fprintf(xyplot, + "%% switch off outline pairs or bases by removing these lines\n" + "drawoutline\n" + "drawpairs\n" + "drawbases\n"); + + if (post) { + fprintf(xyplot, "%% Start Annotations\n"); + fprintf(xyplot, "%s\n", post); + fprintf(xyplot, "%% End Annotations\n"); + } + fprintf(xyplot, "%% show it\nshowpage\n"); + fprintf(xyplot, "end\n"); + fprintf(xyplot, "%%%%EOF\n"); + + fclose(xyplot); + + free(pair_table); + free(X); free(Y); + return 1; /* success */ +} + +/*--------------------------------------------------------------------------*/ + +#define SIZE 452. + +int svg_rna_plot(char *string, char *structure, char *ssfile) +{ + float xmin, xmax, ymin, ymax, size; + int i, length; + float *X, *Y; + FILE *xyplot; + short *pair_table; + + length = strlen(string); + + xyplot = fopen(ssfile, "w"); + if (xyplot == NULL) { + fprintf(stderr, "can't open file %s - not doing xy_plot\n", ssfile); + return 0; + } + + pair_table = make_pair_table(structure); + + X = (float *) space((length+1)*sizeof(float)); + Y = (float *) space((length+1)*sizeof(float)); + if (rna_plot_type == 0) + i = simple_xy_coordinates(pair_table, X, Y); + else + i = naview_xy_coordinates(pair_table, X, Y); + if(i!=length) fprintf(stderr,"strange things happening in PS_rna_plot...\n"); + + + xmin = xmax = X[0]; + ymin = ymax = Y[0]; + for (i = 1; i < length; i++) { + xmin = X[i] < xmin ? X[i] : xmin; + xmax = X[i] > xmax ? X[i] : xmax; + ymin = Y[i] < ymin ? Y[i] : ymin; + ymax = Y[i] > ymax ? Y[i] : ymax; + } + for (i = 0; i < length; i++) + Y[i] = ymin+ymax - Y[i]; /* mirror coordinates so they look as in PS */ + + size = MAX((xmax-xmin),(ymax-ymin)); + size += 10; /* add some so the bounding box isn't too tight */ + + fprintf(xyplot, + "\n" + "\n"); + fprintf(xyplot, + "\n"); + fprintf(xyplot, + " \n" + " \n", + SIZE/size, SIZE/size, (size-xmin-xmax)/2, (size-ymin-ymax)/2); + + fprintf(xyplot, + " \n"); + + fprintf(xyplot," \n"); + for (i = 1; i <= length; i++) { + int j; + if ((j=pair_table[i])>i) + fprintf(xyplot, + " \"\n", + i,j, X[i-1], Y[i-1], X[j-1], Y[j-1]); + } + fprintf(xyplot, " \n"); + fprintf(xyplot, " \n"); + for (i = 0; i < length; i++) + fprintf(xyplot, " %c\n", X[i], Y[i], string[i]); + fprintf(xyplot, " \n"); + fprintf(xyplot, " \n"); + fprintf(xyplot, "\n"); + + fclose(xyplot); + + free(pair_table); + free(X); free(Y); + return 1; /* success */ +} + +/*--------------------------------------------------------------------------*/ + +PUBLIC int ssv_rna_plot(char *string, char *structure, char *ssfile) +{ /* produce input for the SStructView java applet */ + FILE *ssvfile; + int i, bp; + int length; + short *pair_table; + float *X, *Y; + float xmin, xmax, ymin, ymax; + + ssvfile = fopen(ssfile, "w"); + if (ssvfile == NULL) { + fprintf(stderr, "can't open file %s - not doing xy_plot\n", ssfile); + return 0; + } + length = strlen(string); + pair_table = make_pair_table(structure); + + /* make coordinates */ + X = (float *) space((length+1)*sizeof(float)); + Y = (float *) space((length+1)*sizeof(float)); + + if (rna_plot_type == 0) + i = simple_xy_coordinates(pair_table, X, Y); + else + i = naview_xy_coordinates(pair_table, X, Y); + if (i!=length) + fprintf(stderr,"strange things happening in ssv_rna_plot...\n"); + + /* make coords nonegative */ + xmin = xmax = X[0]; + ymin = ymax = Y[0]; + for (i = 1; i < length; i++) { + xmin = X[i] < xmin ? X[i] : xmin; + xmax = X[i] > xmax ? X[i] : xmax; + ymin = Y[i] < ymin ? Y[i] : ymin; + ymax = Y[i] > ymax ? Y[i] : ymax; + } + if (xmin<1) { + for (i = 0; i <= length; i++) + X[i] -= xmin-1; + xmin = 1; + } + if (ymin<1) { + for (i = 0; i <= length; i++) + Y[i] -= ymin-1; + ymin = 1; + } +#if 0 + { + float size, xoff, yoff; + float JSIZE = 500; /* size of the java applet window */ + /* rescale coordinates, center on square of size HSIZE */ + size = MAX((xmax-xmin),(ymax-ymin)); + xoff = (size - xmax + xmin)/2; + yoff = (size - ymax + ymin)/2; + for (i = 0; i <= length; i++) { + X[i] = (X[i]-xmin+xoff)*(JSIZE-10)/size + 5; + Y[i] = (Y[i]-ymin+yoff)*(JSIZE-10)/size + 5; + } + } +#endif + /* */ + + fprintf(ssvfile, + "# Vienna RNA Package %s\n" + "# SStructView Output\n" + "# CreationDate: %s\n" + "# Name: %s\n" + "# Options: %s\n", VERSION, time_stamp(), ssfile, option_string()); + for (i=1; i<=length; i++) + fprintf(ssvfile, "BASE\t%d\t%c\t%d\t%d\n", + i, string[i-1], (int) (X[i-1]+0.5), (int) (Y[i-1]+0.5)); + for (bp=1, i=1; i<=length; i++) + if (pair_table[i]>i) + fprintf(ssvfile, "BASE-PAIR\tbp%d\t%d\t%d\n", bp++, i, pair_table[i]); + fclose(ssvfile); + + free(pair_table); + free(X); free(Y); + return 1; /* success */ +} + +/*---------------------------------------------------------------------------*/ +PUBLIC int xrna_plot(char *string, char *structure, char *ssfile) +{ /* produce input for XRNA RNA drawing program */ + FILE *ss_file; + int i; + int length; + short *pair_table; + float *X, *Y; + + ss_file = fopen(ssfile, "w"); + if (ss_file == NULL) { + fprintf(stderr, "can't open file %s - not doing xy_plot\n", ssfile); + return 0; + } + + length = strlen(string); + pair_table = make_pair_table(structure); + + /* make coordinates */ + X = (float *) space((length+1)*sizeof(float)); + Y = (float *) space((length+1)*sizeof(float)); + + if (rna_plot_type == 0) + i = simple_xy_coordinates(pair_table, X, Y); + else + i = naview_xy_coordinates(pair_table, X, Y); + if (i!=length) + fprintf(stderr,"strange things happening in xrna_plot...\n"); + + fprintf(ss_file, + "# Vienna RNA Package %s, XRNA output\n" + "# CreationDate: %s\n" + "# Options: %s\n", VERSION, time_stamp(), option_string()); + for (i=1; i<=length; i++) + /* XRNA likes to have coordinate mirrored, so we use (-X, Y) */ + fprintf(ss_file, "%d %c %6.2f %6.2f %d %d\n", i, string[i-1], + -X[i-1], Y[i-1], (pair_table[i]?1:0), pair_table[i]); + fclose(ss_file); + + free(pair_table); + free(X); free(Y); + return 1; /* success */ +} + + +/*---------------------------------------------------------------------------*/ +#define PMIN 0.00001 +const char *RNAdp_prolog = +"%This file contains the square roots of the base pair probabilities in the form\n" +"% i j sqrt(p(i,j)) ubox\n\n" +"%%BeginProlog\n" +"/DPdict 100 dict def\n" +"DPdict begin\n" +"/logscale false def\n" +"/lpmin 1e-05 log def\n\n" +"/box { %size x y box - draws box centered on x,y\n" +" 2 index 0.5 mul sub % x -= 0.5\n" +" exch 2 index 0.5 mul sub exch % y -= 0.5\n" +" 3 -1 roll dup rectfill\n" +"} bind def\n\n" +"/ubox {\n" +" logscale {\n" +" log dup add lpmin div 1 exch sub dup 0 lt { pop 0 } if\n" +" } if\n" +" 3 1 roll\n" +" exch len exch sub 1 add box\n" +"} bind def\n\n" +"/lbox {\n" +" 3 1 roll\n" +" len exch sub 1 add box\n" +"} bind def\n\n" +"/drawseq {\n" +"% print sequence along all 4 sides\n" +"[ [0.7 -0.3 0 ]\n" +" [0.7 0.7 len add 0]\n" +" [-0.3 len sub -0.4 -90]\n" +" [-0.3 len sub 0.7 len add -90]\n" +"] {\n" +" gsave\n" +" aload pop rotate translate\n" +" 0 1 len 1 sub {\n" +" dup 0 moveto\n" +" sequence exch 1 getinterval\n" +" show\n" +" } for\n" +" grestore\n" +" } forall\n" +"} bind def\n\n" +"/drawgrid{\n" +" 0.01 setlinewidth\n" +" len log 0.9 sub cvi 10 exch exp % grid spacing\n" +" dup 1 gt {\n" +" dup dup 20 div dup 2 array astore exch 40 div setdash\n" +" } { [0.3 0.7] 0.1 setdash } ifelse\n" +" 0 exch len {\n" +" dup dup\n" +" 0 moveto\n" +" len lineto \n" +" dup\n" +" len exch sub 0 exch moveto\n" +" len exch len exch sub lineto\n" +" stroke\n" +" } for\n" +" [] 0 setdash\n" +" 0.04 setlinewidth \n" +" currentdict /cutpoint known {\n" +" cutpoint 1 sub\n" +" dup dup -1 moveto len 1 add lineto\n" +" len exch sub dup\n" +" -1 exch moveto len 1 add exch lineto\n" +" stroke\n" +" } if\n" +" 0.5 neg dup translate\n" +"} bind def\n\n" +"end\n" +"%%EndProlog\n"; + +int PS_dot_plot(char *string, char *wastlfile) { + /* this is just a wrapper to call PS_dot_plot_list */ + int i, j, k, length, maxl, mf_num; + struct plist *pl; + struct plist *mf; + + length = strlen(string); + maxl = 2*length; + pl = (struct plist *)space(maxl*sizeof(struct plist)); + k=0; + /*make plist out of pr array*/ + for (i=1; i=maxl-1) { + maxl *= 2; + pl = (struct plist *)xrealloc(pl,maxl*sizeof(struct plist)); + } + pl[k].i = i; + pl[k].j = j; + pl[k++].p = pr[iindx[i]-j]; + } + pl[k].i=0; + pl[k].j=0; + pl[k++].p=0.; + /*make plist out of base_pair array*/ + mf_num = base_pair ? base_pair[0].i : 0; + mf = (struct plist *)space((mf_num+1)*sizeof(struct plist)); + for (k=0; k0) { + fprintf(wastl,"%1.2f %1.2f hsb %d %d %1.6f ubox\n", + pi[i].hue, pi[i].sat, pi[i].i, pi[i].j, sqrt(pi[i].p)); + + if (pi[i].mfe) + fprintf(wastl,"%1.2f %1.2f hsb %d %d %1.4f lbox\n", + pi[i].hue, pi[i].sat, pi[i].i, pi[i].j, pi[i].p); + i++; + } + + fprintf(wastl,"showpage\n" + "end\n" + "%%%%EOF\n"); + fclose(wastl); + return 1; /* success */ +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC int simple_xy_coordinates(short *pair_table, float *x, float *y) +{ + float INIT_ANGLE=0.; /* initial bending angle */ + float INIT_X = 100.; /* coordinate of first digit */ + float INIT_Y = 100.; /* see above */ + float RADIUS = 15.; + + int i, length; + float alpha; + + length = pair_table[0]; + angle = (float*) space( (length+5)*sizeof(float) ); + loop_size = (int*) space( 16+(length/5)*sizeof(int) ); + stack_size = (int*) space( 16+(length/5)*sizeof(int) ); + lp = stk = 0; + loop(0, length+1, pair_table); + loop_size[lp] -= 2; /* correct for cheating with function loop */ + + alpha = INIT_ANGLE; + x[0] = INIT_X; + y[0] = INIT_Y; + + for (i = 1; i <= length; i++) { + x[i] = x[i-1]+RADIUS*cos(alpha); + y[i] = y[i-1]+RADIUS*sin(alpha); + alpha += PI-angle[i+1]; + } + free(angle); + free(loop_size); + free(stack_size); + + return length; + +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void loop(int i, int j, short *pair_table) + /* i, j are the positions AFTER the last pair of a stack; i.e + i-1 and j+1 are paired. */ +{ + int count = 2; /* counts the VERTICES of a loop polygon; that's + NOT necessarily the number of unpaired bases! + Upon entry the loop has already 2 vertices, namely + the pair i-1/j+1. */ + + int r = 0, bubble = 0; /* bubble counts the unpaired digits in loops */ + + int i_old, partner, k, l, start_k, start_l, fill, ladder; + int begin, v, diff; + float polygon; + + short *remember; + + remember = (short *) space((1+(j-i)/5)*2*sizeof(short)); + + i_old = i-1, j++; /* j has now been set to the partner of the + previous pair for correct while-loop + termination. */ + while (i != j) { + partner = pair_table[i]; + if ((!partner) || (i==0)) + i++, count++, bubble++; + else { + count += 2; + k = i, l = partner; /* beginning of stack */ + remember[++r] = k; + remember[++r] = l; + i = partner+1; /* next i for the current loop */ + + start_k = k, start_l = l; + ladder = 0; + do { + k++, l--, ladder++; /* go along the stack region */ + } + while (pair_table[k] == l); + + fill = ladder-2; + if (ladder >= 2) { + angle[start_k+1+fill] += PIHALF; /* Loop entries and */ + angle[start_l-1-fill] += PIHALF; /* exits get an */ + angle[start_k] += PIHALF; /* additional PI/2. */ + angle[start_l] += PIHALF; /* Why ? (exercise) */ + if (ladder > 2) { + for (; fill >= 1; fill--) { + angle[start_k+fill] = PI; /* fill in the angles */ + angle[start_l-fill] = PI; /* for the backbone */ + } + } + } + stack_size[++stk] = ladder; + loop(k, l, pair_table); + } + } + polygon = PI*(count-2)/(float)count; /* bending angle in loop polygon */ + remember[++r] = j; + begin = i_old < 0 ? 0 : i_old; + for (v = 1; v <= r; v++) { + diff = remember[v]-begin; + for (fill = 0; fill <= diff; fill++) + angle[begin+fill] += polygon; + if (v > r) + break; + begin = remember[++v]; + } + loop_size[++lp] = bubble; + free(remember); +} + +/*---------------------------------------------------------------------------*/ + + +PUBLIC int PS_dot_plot_list(char *seq, char *wastlfile, + struct plist *pl, struct plist *mf, char *comment) { + FILE *wastl; + int length; + double tmp; + struct plist *pl1; + + length= strlen(seq); + wastl = PS_dot_common(seq, wastlfile, comment, 0); + if (wastl==NULL) return 0; /* return 0 for failure */ + + fprintf(wastl,"%%data starts here\n"); + /* print boxes in upper right half*/ + for (pl1=pl; pl1->i>0; pl1++) { + tmp = sqrt(pl1->p); + fprintf(wastl,"%d %d %1.9f ubox\n", pl1->i, pl1->j, tmp); + } + + /* print boxes in lower left half (mfe) */ + for (pl1=mf; pl1->i>0; pl1++) { + tmp=pl1->p; + fprintf(wastl,"%d %d %1.9f lbox\n", pl1->i, pl1->j, tmp); + } + + fprintf(wastl,"showpage\n" + "end\n" + "%%%%EOF\n"); + fclose(wastl); + return 1; /* success */ +} + +const char *RNAdp_prolog_turn = +"/drawseq_turn {" +"% print sequence at bottom\n" +" gsave\n" +" len 2 sqrt div dup neg 0.28 add exch 0.78 sub translate\n" +" 0 1 len 1 sub {\n" +" dup dup 2 sqrt mul 0 moveto\n" +" sequence exch 1 getinterval\n" +" show\n" +" } for\n" +" grestore\n" +"} bind def\n" +"/drawgrid_turn{\n" +" 0.01 setlinewidth\n" +" len log 0.9 sub cvi 10 exch exp % grid spacing\n" +" dup 1 gt {\n" +" dup dup 20 div dup 2 array astore exch 40 div setdash\n" +" } { [0.3 0.7] 0.1 setdash } ifelse\n" +" 0 exch len { %for (0, gridspacing, len) \n" +" dup dup %duplicate what - gridspacing??\n" +" dup len exch sub moveto %moveto diagonal?\n" +" dup winSize gt\n" +" {dup dup len exch sub winSize add lineto}\n" +" {dup len lineto}ifelse\n" +" dup len exch sub moveto %moveto diagonal?\n" +" dup len winSize sub le\n" +" {dup dup len exch sub dup winSize exch sub len add exch lineto}\n" +" {dup dup len exch sub len exch lineto}ifelse" +" stroke pop pop\n" +" } for\n" +" len log 0.9 sub cvi 10 exch exp % grid spacing\n" +" dup 1 gt {\n" +" dup dup 20 div dup 2 array astore exch 40 div setdash\n" +" } { [0.3 0.7] 0.1 setdash } ifelse\n" +" 0 exch len { %for (0, gridspacing, len) \n" +" dup dup %duplicate what - gridspacing??\n" +" dup len exch sub moveto %moveto diagonal?\n" +" len exch sub 0.7 sub exch 0.7 sub exch lineto\n" +" stroke\n" +" }for\n" +" winSize len moveto len winSize lineto stroke\n" +" [] 0 setdash\n" +" 0.04 setlinewidth \n" +" currentdict /cutpoint known {\n" +" cutpoint 1 sub\n" +" dup dup -1 moveto len 1 add lineto\n" +" len exch sub dup\n" +" -1 exch moveto len 1 add exch lineto\n" +" stroke\n" +" } if\n" +" 0.5 neg dup translate\n" + "} bind def \n\n"; + +int PS_color_dot_plot_turn(char *seq, cpair *pi, char *wastlfile, int winSize) { + /* produce color PostScript dot plot from cpair */ + + FILE *wastl; + int i, length; + + length= strlen(seq); + wastl = PS_dot_common(seq, wastlfile, NULL, winSize); + if (wastl==NULL) + return 0; /* return 0 for failure */ + + fprintf(wastl, "/hsb {\n" + "dup 0.3 mul 1 exch sub sethsbcolor\n" + "} bind def\n\n" + "%%BEGIN DATA\n"); + + /* print boxes */ + i=0; + while (pi[i].j>0) { + fprintf(wastl,"%1.2f %1.2f hsb %d %d %1.6f ubox\n", + pi[i].hue, pi[i].sat, pi[i].i, pi[i].j, sqrt(pi[i].p));/*sqrt??*/ + + if (pi[i].mfe) + fprintf(wastl,"%1.2f %1.2f hsb %d %d %1.4f lbox\n", + pi[i].hue, pi[i].sat, pi[i].i, pi[i].j, pi[i].p); + i++; + } + + fprintf(wastl,"showpage\n" + "end\n" + "%%%%EOF\n"); + fclose(wastl); + return 1; /* success */ +} + +int PS_dot_plot_turn(char *seq, struct plist *pl, char *wastlfile, int winSize) { + /* produce color PostScript dot plot from cpair */ + + FILE *wastl; + int i, length; + + length= strlen(seq); + wastl = PS_dot_common(seq, wastlfile, NULL, winSize); + if (wastl==NULL) + return 0; /* return 0 for failure */ + + /* print boxes */ + i=0; + while (pl[i].j>0) { + fprintf(wastl,"%d %d %1.4f ubox\n", + pl[i].i, pl[i].j, sqrt(pl[i].p)); + i++; + } + + fprintf(wastl,"showpage\n" + "end\n" + "%%%%EOF\n"); + fclose(wastl); + return 1; /* success */ +} + +static FILE * PS_dot_common(char *seq, char *wastlfile, + char *comment, int winsize) { + /* write PS header etc for all dot plot variants */ + FILE *wastl; + char name[31], *c; + int i, length; + + length= strlen(seq); + wastl = fopen(wastlfile,"w"); + if (wastl==NULL) { + fprintf(stderr, "can't open %s for dot plot\n", wastlfile); + return NULL; /* return 0 for failure */ + } + strncpy(name, wastlfile, 30); + if ((c=strrchr(name, '_'))!=0) *c='\0'; + + fprintf(wastl, + "%%!PS-Adobe-3.0 EPSF-3.0\n" + "%%%%Title: RNA Dot Plot\n" + "%%%%Creator: %s, ViennaRNA-%s\n" + "%%%%CreationDate: %s", rcsid+5, VERSION, time_stamp()); + if (winsize>0) + fprintf(wastl, "%%%%BoundingBox: 66 530 520 650\n"); + else + fprintf(wastl, "%%%%BoundingBox: 66 211 518 662\n"); + fprintf(wastl, + "%%%%DocumentFonts: Helvetica\n" + "%%%%Pages: 1\n" + "%%%%EndComments\n\n" + "%%Options: %s\n", option_string()); + + if (comment) fprintf(wastl,"%% %s\n",comment); + + fprintf(wastl,"%s", RNAdp_prolog); + + fprintf(wastl,"DPdict begin\n" + "%%delete next line to get rid of title\n" + "270 665 moveto /Helvetica findfont 14 scalefont setfont " + "(%s) show\n\n", name); + + fprintf(wastl,"/sequence { (\\\n"); + for (i=0; i0) + fprintf(wastl,"/winSize %d def\n",winsize); + fprintf(wastl,"/len { sequence length } bind def\n\n"); + if (cut_point>0) fprintf(wastl,"/cutpoint %d def\n\n", cut_point); + + + if (winsize>0) + fprintf(wastl,"292 416 translate\n" + "72 6 mul len 1 add winSize add 2 sqrt mul div dup scale\n"); + else + fprintf(wastl,"72 216 translate\n" + "72 6 mul len 1 add div dup scale\n"); + fprintf(wastl, "/Helvetica findfont 0.95 scalefont setfont\n\n"); + + if (winsize>0) { + fprintf(wastl, "%s", RNAdp_prolog_turn); + fprintf(wastl,"0.5 dup translate\n" + "drawseq_turn\n" + "45 rotate\n" + "drawgrid_turn\n"); + } + else + fprintf(wastl,"drawseq\n" + "0.5 dup translate\n" + "%% draw diagonal\n" + "0.04 setlinewidth\n" + "0 len moveto len 0 lineto stroke \n\n" + "drawgrid\n"); + return(wastl); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/PS_dot.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/PS_dot.o new file mode 100755 index 0000000000000000000000000000000000000000..d9c50537143cbd4472d720005f670d69fb276737 GIT binary patch literal 60248 zcmdtLd02$lDKC3g1`~h(22t{dXXEGSJ%B+|<;x@8tP`>;9T^xO7w|Y6$H6 zz<#=K%;6m~ew_;0cMvO&9^5gfueA8XXz8e-{%!NYlqUb+Gw{-};h{Y**Ukg+h zl|*aHEXeP;+|yJR1)-AY$7O}Rpz`-6eZ7I;VgF;LWmfU=$a^K%o%EFKsQlEwa~BjI z=utM5>_{CPxb;K-^3pA-C;ZFyo$xR3{m?%Ma;4EH#ykZwDRlW%%;i(%!TlhWx<#O= zTgrp`;=zq0kDaTFIh?xXMSuA$rMd4nfm~j>%amHM^T`wb%dx^wY+4ZLnTZr^kMdw|;gJ&M|1p0%HhlMv z)Zu;m(FYl+H+%>l0`H{WQ2d*XZ-cT;P%ISI3!jh!At-C(qq;6V6{9jMq90I|+}cD3 zZdHL1xbE?s6)Q_>OIDU#UQ%}eO4k3EEG>_IR8mtOeGa3pQq(zPD4fBJHR0;K4v^FGgix-#d16e`)j`2+yZK9! zDp#_j+Y^ZXxv-DG!^%163pe%7(NleWfuL%dfUaCw^un^}=#od!;r^w)*X8a`DJ%Y~ zf7c$!2YSZCC&c7S;A3zNHpTLayC8lBm5$1QPjHMXo0|ec2*O`QUI{q&E@)sNDychB zs$!HchR^*6N>rjgNAyl8vGfiI|o;l}XdkIN-p< z?E|C2lJe+39>rRgRAbxx5!%KVh|U-li2h0I-QHUsecZoo8g}QN8KV>!JqYozW2Hwk zf-jaw4+r+Wo)UdoUwyeedPt>U$k1Ni-s|7?CKOT;eYYa|&x&ZDx?KEDU#da@`2I&LGWt|=Y(EwK^IjYpn_y@v^FQ`viT~@peFs!KU-ycxSn;uqKLR18 zpG~faenfd4gAn^Z)mepuV=H-dxZ6??pUS$zUZn(u3wwnm_FDZ9yHLqer}JRbe5gdB zeKG^lYe!|oG|*xHw((G#Ko49{s-p)3(U(OF1z^zj8Ete>G4((NZM^-6f7^qqm9GVA zbbm$keMOM1lnWj+S_wV9z)~%N$)Tf;T}V}c_5hD!Lu|J`^sn6K&v^oKsoNm4-=FhT z@v&>6V`ZERIxT zf6i}E%#ldl<_e^4+xWKPYo9yu^a8}wg6MG-QWQ{qg}rV_9Sf*{svecW5w*Nx+bIYH zuwr@X_ERdDV8DT}f$pj1AULZ~J5lP-eG)%(J3}Bnp!Aj~-$5nMMi&Kos=?901OCTS zXBR)eX;I$+AVUApoderaj~39^l<6Fc5H^`+%qg~Lw4-xziiw^miS|ZcaBBxEfIi)y zj{O&n7!}bI>be_~nF(T&;}J*l^61}rs3^iv%u&`UB@lE`9aaGxHxBx@ea&lG5QmQK z$p;HPjbk7_39AbbQ`Jd0Sd2>?hW(u=95@Q6{!zC2#59c5>T|@gg>H~sj}hr#Susj8 z;4`BFW$K(b1v#5ZBeViV0%br_Y9We$j6t{|M_mEdGAIn&*PpYG%c@lYiF3lXYu^DL zm{t)z3W;j8tF{y^sI49~;^C`fYF79nl=Bp5R5KQoH&lU}JO>X@qIz?Uj9r*W*M=!L9AN*e7?s0DYm32YY_$K;p}rWypNco! zDd)8Ka*&-6=FY6UxjUigi3U1%k=ePO@e~KZdCssRr426h#trkoZ!RroeUAjmZSTzH)AJIU0M$zM?aMP zS;yzmD?h=T%IZ;lhCN4j!v!ap&E;rL(#{X@0ypD@PacID!`-D`50pp$gc}RL#~~qR zi3)=PG*`?L749LfrzNVbTQvHzGe+R(QR08}&~+!5`L{g@F>>9>bphCnz`H#Q6FyA% zxBUbzk??_ELt1Cbqk1iOQm*CRre>;$zWVS`U>eO-TKt}W=Usr~b+F64?kref8Kwue zFWPcAtw5hWs2mS!{Et@qU}34uF4_F)GS~=#(>mS?37`Qmz6k^R^b!h8+|*Ur8-15G zDHUbg{@Hzdyq?Hj8XzkmHr&Gd4nj|^*m?>+OShbIJ9K=ZN;wp{affm&q&A!j!?jyF zSn@*jFHF1kb*A}u{Za)bEM=fz=;*VHkNS6Qg&Or8JoYjU`GMezF}EIKoL8F_dYtcz z%yh?ibhdUojPm|%K2?HRV?TUhjIWeEN8eFFjokv}pl>Mn*a2xhdG%y zdo=XJBptwv_wwi`F(Ds)88S=fmfLv4QCS3D9liqjf6(b|CsDb0gkE z6voOFo|FoE1A1EGKrGw-Pet(W>;T1plF>?!x}t^zh8Jw_iwx%axol_A|CTOaI;ikH zg<)v;<9&SWtob{Jj#C9Gbz2TPvrr)T7rsYrOSd1{=r{PF#=rA=E%WgF_+qg11ox>}`fQ{6NS&HU!z(x>iyL!g!qFQb3Jqh9 z{SkFch|zJh+l??|eO1_d?0b6fgikeU2BQB6M4u}>QiU5Y?|c*D7;c*idlzhf&%f;k zP+QuwAQd)jVV7cKUEzzzCI@z;u7I5=GUEeSO$7G6lG0O=liD*>Pa?WufmYg6x;?dQ zd+)~4D1_s{cGzHAw6DpZ*L!tJGSI^2+*aqJD5TH<#}l=f5~gvuV-xQZ)#aGYG)xL=0~DpkBlJa$gcC8<3_7$bcL1}YPJywHwtYr6ar*@VA$YK6B5#~!PQzJBaH zAkFcCsw9erz$W!ee2oV_TBkaT5NKqz|MVEnvA9bJEnWB?#;BUvVT6UTRv89U_>NTA z=syWl_`tx98JnEl+_K^iaOZHxe}M`WUnM*0Jg|`5w0=SGqX4b&^-ce=0a%_|7j9ZH zyC?M*d>1<-aM69W;1QEf*j#9X*FrZ7|lFeYn)d zm7O&^T5bDiqZo$uh_|#S2R5xeAOhRgva&E;!kxv2LaJBclTaUJjUEEWB z$QK=YR!`}nfzi^lQUllR8wfJjz6d0}o>LPSR7e>Wh`vyww)(Mp(dta!;Z*g#Ohxpy z!=;(ZHXWI`hB~a05VRUn8@?yS;Dw%ptDfFK@VIWJNoxZ8-l9GCn1+A`J9;;aa=N{i z6h0Z(!#_GHd-y-VNjLybfwMb)JAJ(@6*hi%J^&Y?uP?-o`5*W7p3-r??Y*+6_mmz4 zwHxab_Ve4^9V!~-438|VQoNIByIVCI8JIuLxiG$i=*R51YbyKvwj z&tT6ixMzheDaC=pQXo4BvS=V>2TzL04uLExq^m>4RnR{S^aNQ{mrm}+q`r7sKi`d<@$^@hQ}VtANdGB{ zU|G+n z{A|kap?s;b#yj#J%Fp$DNAZ8;v3$OMzKbApIyN1Kk>&kaf2=4TnciPOKL_X`U3E+6 z_UfAZbnX$|lo?h(-+Ykk=ffr+hz6s|Gp<1efX)G6;D1YW9K}sP03m2~-1$=bzo+tm z^dFwyYV|*pLM8nQtAD0Wr|RJAf7TN~?O%mUNjNh54F-O{AugZOsp+emLe3RmdZ*QI zC`zS_9GKqH4Ob|ak=|7wadJboeW|G`l=}@kiG_WG3LDrj6AL>_6m~Wlhw9JK>V1~~ z&q^A)-W0FX`?S6KGo#h=O!T5C9vN52+#rPDD(e`m@>3o5kg(;M;pA`=g!3tDGj;YN zbvb42P%W#oNE~vd^Uy9!cZ4(6S)Oz+isF&6Ugm})p}-PM(AsURbHousPqtMu3=8a zw3L}2?q~tiu~x$>U`A1`@2N=n9MdmJ*@|Ytp{tTSuM1z0g39qg(=JWnNYYmq8u`i; 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These profiles + can be aligned using standard string alignment. + + The is an extension of the old method in ProfileDist.c with the + following changes: + - use sequence as well as structure profile for scoring + - use similarity alignment instead of distance (maybe add local alinment) + - use affine gap costs + + C Ivo L Hofacker, Vienna RNA Package +*/ +/* Last changed Time-stamp: <2004-08-02 10:11:13 ivo> */ + +#include +#include +#include +#include +#include +#include +#include "dist_vars.h" +#include "fold_vars.h" +#include "part_func.h" +#include "utils.h" +/*@unused@*/ +static char rcsid[] = "$Id: ProfileAln.c,v 1.5 2006/01/18 13:00:30 ivo Exp $"; + +#define PUBLIC +#define PRIVATE static +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MAX3(x,y,z) (MAX( (MAX((x),(y))) ,(z))) +#define EQUAL(x,y) (fabs((x)-(y)) <= fabs(x)*2*FLT_EPSILON) + +PRIVATE int *alignment[2]; + +PUBLIC float profile_aln(const float *T1, const char *seq1, + const float *T2, const char *seq2); + +PUBLIC int set_paln_params(double gap_open, double gap_ext, + double seqweight, int free_ends); + +PRIVATE void sprint_aligned_bppm(const float *T1, const char *seq1, + const float *T2, const char *seq2); +PRIVATE double PrfEditScore(const float *p1, const float *p2, + char c1, char c2); +PRIVATE double average(double x, double y); + +PRIVATE double open=-1.5, ext=-0.666; /* defaults from clustalw */ +PRIVATE double seqw=0.5; +PRIVATE int free_ends=1; /* whether to use free end gaps */ +extern float *Make_bp_profile(int length); + +/*---------------------------------------------------------------------------*/ + +PRIVATE float **newmat(int l1, int l2) { + float **a; + int i; + a = (float **) space((l1+1)*sizeof(float *)); + for (i=0; i<=l1; i++) a[i] = (float *) space((l2+1)*sizeof(float)); + return a; +} + +PUBLIC float profile_aln(const float *T1, const char *seq1, + const float *T2, const char *seq2) +{ + /* align the 2 probability profiles T1, T2 */ + /* This is like a Needleman-Wunsch alignment, with affine gap-costs + ala Gotoh. The score looks at both seq and pair profile */ + + float **S, **E, **F, tot_score; + int i, j, length1, length2; + + length1 = strlen(seq1); + length2 = strlen(seq2); + S = newmat(length1, length2); + E = newmat(length1, length2); + F = newmat(length1, length2); + + E[0][0] = F[0][0] = open - ext; + S[0][0] = 0; + for (i=1; i<=length1; i++) F[i][0] = -9999; /* impossible */ + for (j=1; j<=length2; j++) E[0][j] = -9999; /* impossible */ + if (!free_ends) { + for (i=1; i<=length1; i++) S[i][0] = E[i][0] = E[i-1][0] +ext; + for (j=1; j<=length2; j++) S[0][j] = F[0][j] = F[0][j-1] +ext; + } + + for (i=1; i<=length1; i++) { + for (j=1; j<=length2; j++) { + float M; + E[i][j] = MAX(E[i-1][j]+ext, S[i-1][j]+open); + F[i][j] = MAX(F[i][j-1]+ext, S[i][j-1]+open); + M = S[i-1][j-1] + PrfEditScore(T1+3*i,T2+3*j, seq1[i-1], seq2[j-1]); + S[i][j] = MAX3(M, E[i][j], F[i][j]); + } + } + + if (edit_backtrack) { + double score=0; + char state = 'S'; + int pos, i,j; + alignment[0] = (int *) space((length1+length2+1)*sizeof(int)); + alignment[1] = (int *) space((length1+length2+1)*sizeof(int)); + + pos = length1+length2; + i = length1; + j = length2; + + tot_score = S[length1][length2]; + + if (free_ends) { + /* find starting point for backtracking, + search for highest entry in last row or column */ + int imax=0; + for (i=1; i<=length1; i++) { + if (S[i][length2]>score) { + score=S[i][length2]; + imax=i; + } + } + for (j=1; j<=length2; j++) { + if (S[length1][j]>score) { + score=S[length1][j]; + imax=-j; + } + } + if (imax<0) { + for (j=length2; j> -imax; j--) { + alignment[0][pos] = 0; + alignment[1][pos--] = j; + } + i=length1; + } else { + for (i=length1; i>imax; i--) { + alignment[0][pos] = i; + alignment[1][pos--] = 0; + } + j=length2; + } + tot_score=score; + } + + while (i>0 && j>0) { + switch (state) { + case 'E': + score = E[i][j]; + alignment[0][pos] = i; + alignment[1][pos--] = 0; + if (EQUAL(score, S[i-1][j] + open)) state = 'S'; + i--; + break; + case 'F': + score = F[i][j]; + alignment[0][pos] = 0; + alignment[1][pos--] = j; + if (EQUAL(score, S[i][j-1] + open)) state = 'S'; + j--; + break; + case 'S': + score = S[i][j]; + if (EQUAL(score, E[i][j])) state = 'E'; + else if (EQUAL(score, F[i][j])) state = 'F'; + else if (EQUAL(score, S[i-1][j-1] + + PrfEditScore(T1+3*i,T2+3*j, seq1[i-1], seq2[j-1]))) { + alignment[0][pos] = i; + alignment[1][pos--] = j; + i--; j--; + } + else nrerror("backtrack of alignment failed"); + break; + } + } + + for (; j>0; j--) { + alignment[0][pos] = 0; + alignment[1][pos--] = j; + } + for (; i>0; i--) { + alignment[0][pos] = i; + alignment[1][pos--] = 0; + } + + for(i=pos+1; i<=length1+length2; i++){ + alignment[0][i-pos] = alignment[0][i]; + alignment[1][i-pos] = alignment[1][i]; + } + alignment[0][0] = length1+length2-pos; /* length of alignment */ + + sprint_aligned_bppm(T1,seq1, T2,seq2); + free(alignment[0]); + free(alignment[1]); + } + for (i=0; i<=length1; i++) { + free(S[i]); free(E[i]); free(F[i]); + } + free(S); free(E); free(F); + + return tot_score; +} + + +/*---------------------------------------------------------------------------*/ +PRIVATE inline double average(double x, double y) { + /* + As in Bonhoeffer et al (1993) 'RNA Multi Structure Landscapes', + Eur. Biophys. J. 22: 13-24 we have chosen the geometric mean. + */ + return (float) sqrt(x*y); +} + +PRIVATE double PrfEditScore(const float *p1, const float *p2, char c1, char c2) +{ + double score; + int k; + + for(score=0.,k=0; k<3; k++) + score += average(p1[k],p2[k]); + + score *= (1- seqw); + if (c1==c2) score += seqw; + else if (((c1=='A') && (c2=='G')) || + ((c1=='G') && (c2=='A')) || + ((c1=='C') && (c2=='U')) || + ((c1=='U') && (c2=='C'))) + score += 0.5*seqw; + else score -= 0.9*seqw; + return score; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void sprint_aligned_bppm(const float *T1, const char *seq1, + const float *T2, const char *seq2) { + int i, length; + length = alignment[0][0]; + for (i=0; i<4; i++) { + if (aligned_line[i] != NULL) free(aligned_line[i]); + aligned_line[i] = (char *) space((length+1)*sizeof(char)); + } + for(i=1; i<=length; i++){ + if (alignment[0][i]==0) + aligned_line[0][i-1] = aligned_line[2][i-1] = '_'; + else { + aligned_line[0][i-1] = bppm_symbol(T1+alignment[0][i]*3); + aligned_line[2][i-1] = seq1[alignment[0][i]-1]; + } + if (alignment[1][i]==0) + aligned_line[1][i-1] = aligned_line[3][i-1] = '_'; + else { + aligned_line[1][i-1] = bppm_symbol(T2+alignment[1][i]*3); + aligned_line[3][i-1] = seq2[alignment[1][i]-1]; + } + } +} + +PUBLIC int set_paln_params(double gap_open, double gap_ext, + double seq_weight, int freeends) { + open = (gap_open>0) ? -gap_open : gap_open; + ext = (gap_ext>0) ? -gap_ext : gap_ext; + if (open > ext) fprintf(stderr, "Gap extension penalty is smaller than " + "gap open. Do you realy want this?\n"); + seqw = seq_weight; + if (seqw<0) { + seqw = 0; + fprintf(stderr, "Sequence weight set to 0 (must be in [0..1])\n"); + } else + if (seqw>1) { + seqw = 1; + fprintf(stderr, "Sequence weight set to 1 (must be in [0..1])\n"); + } + free_ends = (freeends) ? 1 : 0; + return 0; +} + +/*---------------------------------------------------------------------------*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/ProfileAln.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/ProfileAln.o new file mode 100755 index 0000000000000000000000000000000000000000..7920bd0956b43d50a2f37c50953c4347d3596a5d GIT binary patch literal 21616 zcmb_k3w)HtwV!Wy6Bdctd{m&|3w&^|Xzn>P=X^VvB(}fa zJ3scDbN+MYoHJ+6%zWRs8`@@8%yL+k;9`kyi7dyc5FZs~>1mRjCWeclq9R@EKM_cu z52dU9uLQQ-=C?xWM*p#jbjp9O0;rEl-Vbd!T@Z?Orq71<9Cx0;zQIX%b0cq>*}_{zfkPY!SsinPiN&^Z>;@mMf#&qW|%*eY4p1*GPQnh1yDmOGAX|= zv|)e2zB<(zubzc3NMFbe@Gg}8RC*$PDhF3LoDK!jF9p)imb?!3_MP?I9Bdb71D>1n 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/ProfileDist.c @@ -0,0 +1,242 @@ +/* + Functions for handling the Base Pair Probability Matrix + Peter F Stadler, Ivo L Hofacker + Vienna RNA Package +*/ +/* Last changed Time-stamp: <2002-11-07 12:46:16 ivo> */ + +#include +#include +#include +#include +#include +#include "dist_vars.h" +#include "fold_vars.h" +#include "part_func.h" +#include "utils.h" +/*@unused@*/ +static char rcsid[] = "$Id: ProfileDist.c,v 1.6 2002/11/07 11:49:59 ivo Exp $"; + +#define PUBLIC +#define PRIVATE static +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MIN3(x,y,z) (MIN( (MIN((x),(y))) ,(z))) + +PRIVATE int *alignment[2]; + +PUBLIC float profile_edit_distance(const float *T1, const float *T2); +PUBLIC float *Make_bp_profile(int length); +PUBLIC void free_profile(float *T); +PRIVATE void sprint_aligned_bppm(const float *T1, const float *T2); +PRIVATE double PrfEditCost(int i, int j, const float *T1, const float *T2); +PRIVATE double average(double x, double y); + +/*---------------------------------------------------------------------------*/ + +PUBLIC float profile_edit_distance(const float *T1, const float *T2) +{ + /* align the 2 probability profiles T1, T2 */ + /* This is like a Needleman-Wunsch alignment, + we should really use affine gap-costs ala Gotoh */ + + float **distance; + short **i_point, **j_point; + + int i, j, i1, j1, pos, length1,length2; + float minus, plus, change, temp; + + length1 = (int) T1[0]; + length2 = (int) T2[0]; + distance = (float **) space((length1 +1)*sizeof(float *)); + if(edit_backtrack){ + i_point = (short **) space((length1 +1)*sizeof(short *)); + j_point = (short **) space((length1 +1)*sizeof(short *)); + } + for(i=0; i<= length1; i++){ + distance[i] = (float *) space( (length2+1)*sizeof(float)); + if(edit_backtrack){ + i_point[i] = (short *) space( (length2+1)*sizeof(short)); + j_point[i] = (short *) space( (length2+1)*sizeof(short)); + } + } + + for(i = 1; i <= length1; i++) { + distance[i][0] = distance[i-1][0]+PrfEditCost(i,0,T1,T2); + if(edit_backtrack){ i_point[i][0] = (short) i-1; j_point[i][0] = 0; } + } + for(j = 1; j <= length2; j++) { + distance[0][j] = distance[0][j-1]+PrfEditCost(0,j,T1,T2); + if(edit_backtrack){ i_point[0][j] = 0; j_point[0][j] = (short) j-1; } + } + for (i = 1; i <= length1; i++) { + for (j = 1; j <= length2 ; j++) { + minus = distance[i-1][j] + PrfEditCost(i,0,T1,T2); + plus = distance[i][j-1] + PrfEditCost(0,j,T1,T2); + change = distance[i-1][j-1]+ PrfEditCost(i,j,T1,T2); + + distance[i][j] = MIN3(minus, plus, change); + /* printf("%g ", distance[i][j]); */ + + if(edit_backtrack){ + if(distance[i][j] == change) { + i_point[i][j]= (short)i-1; j_point[i][j]= (short) j-1; } + else if(distance[i][j] == plus) { + i_point[i][j]= (short)i ; j_point[i][j]= (short)j-1; } + else { + i_point[i][j]= (short)i-1; j_point[i][j]= (short)j ; } + } + } + /* printf("\n"); */ + } + /* printf("\n"); */ + temp = distance[length1][length2]; + for(i=0;i<=length1;i++) + free(distance[i]); + free(distance); + + if(edit_backtrack){ + alignment[0] = (int *) space((length1+length2+1)*sizeof(int)); + alignment[1] = (int *) space((length1+length2+1)*sizeof(int)); + + pos = length1+length2; + i = length1; + j = length2; + while( (i>0)||(j>0) ) { + i1 = i_point[i][j]; + j1 = j_point[i][j]; + if( ((i-i1)==1)&&((j-j1)==1) ) { /* substitution */ + alignment[0][pos] = i; + alignment[1][pos] = j; + } + if( ((i-i1)==1)&&(j==j1) ) { /* Deletion in [1] */ + alignment[0][pos] = i; + alignment[1][pos] = 0; + } + if( (i==i1)&&((j-j1)==1) ) { /* Deletion in [0] */ + alignment[0][pos] = 0; + alignment[1][pos] = j; + } + pos--; + i = i1; + j = j1; + } + for(i=pos+1; i<=length1+length2; i++){ + alignment[0][i-pos] = alignment[0][i]; + alignment[1][i-pos] = alignment[1][i]; + } + alignment[0][0] = length1+length2-pos; /* length of alignment */ + + for(i=0; i<=length1; i++){ + free(i_point[i]); free(j_point[i]); + } + free(i_point); free(j_point); + sprint_aligned_bppm(T1,T2); + free(alignment[0]); + free(alignment[1]); + } + + return temp; +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE double PrfEditCost(int i, int j, const float *T1, const float *T2) +{ + double dist; + int k, kmax; + + kmax = (int) T1[1]; + if ((int) T2[1] != kmax) nrerror("inconsistent Profiles in PrfEditCost"); + + if(i==0) { + for(dist = 0. ,k=0 ; k0)&&(j>0)) { + for(dist = 2.,k=0; k= 0 for 0<= x,y <= 1 + 3.) a(x,y) <= (x+y)/2 + 4.) a(x,x) >= a(x,y) for 0<= x,y <= 1 + As in Bonhoeffer et al (1993) 'RNA Multi Structure Landscapes', + Eur. Biophys. J. 22: 13-24 we have chosen the geometric mean. +*/ + +{ + float a; + a = (float) sqrt(x*y); + return a; +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC float *Make_bp_profile(int length) +{ + int i,j; + int L=3; + float *P; /* P[i*3+0] unpaired, P[i*3+1] upstream, P[i*3+2] downstream p */ + + P = (float *) space((length+1)*3*sizeof(float)); + /* indices start at 1 use first entries to store length and dimension */ + P[0] = (float) length; + P[1] = (float) L; + + for( i=1; i0uzlbj}QX}CX>lTB6&HPAheL6 z7;uacRBlC0tM+MqTxq{sinYo^5Zj`qwqmsvtgRJ9g+edVTFhN*@3qeCoXOli?*5o_ z*82B)?X}n5=aEB4N!h$K!w}pIFwcu?#YVBJkI0D`n&udXPs*( zU?rXB+VTp1Tj#p*^`evO$NA&?T+hDI?HJknQqjr4_Om|MGRK`~T$P8{ovf>?+Y0|m zI`_0qvJ@`&$IsXm{GH$rG(JQHkU!^obYH<9&~rVyr*og{&U+vNG%$2H#!__B)%|5S zm&89UiNEZ3J$nIu|8sK08P~Es7{pmPgE{zB9bRAV>voJ)VU=|XV8$e3T>8ox*TTJZ zF7KW%r^WW3ab>{|N8S6995dQ0I;jS&+g$f_VB`Km5Z`yxa$l8ixo?Fp_>vl{9Ivl@ z$qP6?i{qaK!o7j+Ssjq;tnOJa3t5XHr3T@znA>lz}~uPy5u z4KkvvOAgfc6BC%N-8UFTZ*?s0o>p2Ge)Wd%{<&R_uCsGo%lw-if$))yFPjry32Z;( zb5%O_Vb_FLdiMsl7rlkygV+!dgXsMaI+cio0e#TfzO(m$Z{vQm=$&;vGT@?jIwnFj zT#O+E!UtTrdjs8$;@$%gYqw+bSyxptSgI;^Vyx{)AqiQ5_<76$jUFc({`qb!jeiRD zwgeJ^Wwr)vx&rZao@%JDy}%5B^WnJPQ`WmDuszT{>Hs>7mwN*7V=_IZ@dI7yh(Q5# zMj;0!1?T)TW1g~(2$W$!Y2|gIL|L~-oV>`_`?BgUDGeWupCTjvcLbY>z2lF608+9i z&{giK1U?XVye$E#i|7J`+MoBmh|{Mm)|ZAq!LI6pbERGWkI$FI|LTu_TH00hv4E`N zGVyx~k3aPH-d-p2J#M3G8o5AAd00j&H`s>K@YqUD>SVV>^cun|Xbg|9$LrY|Km5?pUURb8Yzmq|wazK=>V%hjS|Rkafp)nTFis<36Lb=N4d=q+2N*|AfmN z<6Gw6t`g@ye)?~u;g(rd9&mbLQbFagCY%F<8s<6vB51%+hI!=t=13ndZ@I@0;;*JAap3ro8`L7rjp@?wB1=bpVT} z%ds7ycnytMJWadLvZe+YyxsDQxV^U{~=#q%70HpuQPI==pGSQyUT7lDtPmgCOE zn;%$^EJDVt+Gdsh~yew0QG>2ibT+*UprXkLl5&ZP@yEDuTcr5G#Kq@EoxxL z=q}OW*hIe&?!G=a5tsJ^gROB1)oTaOf_t&?3D*knBqT<`B#Xx(zBE|`PS|YvZ&rsC zbPkj!!zoW`igOS+K!NFIeN#+0(v?Cw+yM&V*s=nTlH7`<>KvHvyo(uQz<@~-72-E( z-hn7;4mNJY?(ssgLyS8l>s0JeVzU&RO>B;0hY{;m>~Lap6+431DT=*>*h0nT5L>L+ zk;DcRdl|6{6g!I8O2v*bR>3gR##bxWZQLr^m5LolBWh9XmBhvrn`=bm0M{rs&zOl> z7{9?#{A8n4@^=vLHEsjj=J<`oPc=46{x0HY8ZA+*qWUa$$XW^lwwb$u%zl9QVQ6D`kJSsq zi~%!Z7eso=cL+9qC?hv=)(GQCbeFT1h)YAl*om@YKVS-5`oFZWI}lYl1fw5GN!>r;tn9?Vl{=7Odse0)G)@kM8$wnH%L0&iS;YH2aNs!kf7TFJ=Q|M zT6oZe3p3;9ObJbBfqURnqS`( zZfL8G2%X8VsgJb^uQxv+#DZvZU428uU*8(@hS7X$thT<{yAo5}P+!AjY;8-V6;Oz! z7DR)qLs4WQh`Q#6T8)LsKt?t5KErU{S5Y2F`@)cl(}jVZTk*I*=BzM>J1>~4=9|Ok zmza$mX7(iK?dB?Hw>f;0xeAXD0h({-I1iW?6`8A-%x)-qZq}8vTJCVxo_?~XCp39N z-jmM76CeBh;ed0L*F4hh>@YJfm~HdTj3t5g(w%{xH`69&z1MT~te(Qa!lm)6UQWx; 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+ +PUBLIC char *b2HIT(const char *structure); /* Full -> HIT [incl. root] */ +PUBLIC char *b2C(const char *structure); /* Full -> Coarse [incl. root] */ +PUBLIC char *b2Shapiro(const char *structure); /* Full -> weighted Shapiro [i.r.] */ +PUBLIC char *add_root(const char *structure); /* {Tree} -> ({Tree}R) */ + +PUBLIC char *expand_Shapiro(const char *structure); /* Coarse [i.r.] -> unweighted Shapiro */ +PUBLIC char *expand_Full(const char *structure); /* Full -> FFull */ +PUBLIC char *unexpand_Full(const char *structure); /* FFull -> Full */ + +PUBLIC void parse_structure(const char *structure); /* guess !!! */ + +PRIVATE char *aux_struct(const char *structure); + +/* on return from parse_structure(), b2C() or b2Shapiro() ... */ +PUBLIC int loop_size[STRUC]; /* contains loop sizes of a structure */ +PUBLIC int helix_size[STRUC]; /* contains helix sizes of a structure */ +PUBLIC int loop_degree[STRUC]; /* contains loop degrees of a structure */ +PUBLIC int loops; /* n of loops and stacks in a structure */ +PUBLIC int unpaired, pairs; /* n of unpaired digits and pairs */ + +/*---------------------------------------------------------------------------*/ + +PRIVATE char *aux_struct(const char* structure ) +{ + short *match_paren; + int i, o, p; + char *string; + + string = (char *) space(sizeof(char)*(strlen(structure)+1)); + match_paren = (short *) space(sizeof(short)*(strlen(structure)/2+1)); + strcpy(string, structure); + + i = o = 0; + while (string[i]) { + switch (string[i]) { + case '.': break; + case '(': + match_paren[++o]=i; + break; + case ')': + p=i; + while ((string[p+1]==')')&&(match_paren[o-1]==match_paren[o]-1)) { + p++; o--; + } + string[p]=']'; + i=p; + string[match_paren[o]]='['; + o--; + break; + default: + nrerror("Junk in structure at aux_structure\n"); + } + i++; + } + free(match_paren); + return(string); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char *b2HIT(const char *structure) +{ + + int i, u, p, l; + char *string, *temp, *HIT, tt[10]; + + temp = (char *) space(strlen(structure)*4+4); + string = aux_struct( structure ); + + strcpy(temp,"("); + i=p=u=0; l=1; + while (string[i]) { + switch(string[i]) { + case '.': + u++; break; + case '[': + if (u>0) { + sprintf(tt, "(U%d)" , u); + strcat(temp+l, tt); + l+=strlen(tt); + u=0; + } + strcat(temp+l, "("); l++; + break; + case ')': + if (u>0) { + sprintf(tt, "(U%d)" , u); + strcat(temp+l, tt); + l+=strlen(tt); + u=0; + } + p++; + break; + case ']': + if (u>0) { + sprintf(tt, "(U%d)" , u); + strcat(temp+l, tt); + l+=strlen(tt); + u=0; + } + sprintf(tt,"P%d)", p+1); + strcat(temp+l, tt); + l+=strlen(tt); + p=0; + break; + } + i++; + } + if (u>0) { + sprintf(tt, "(U%d)" , u); + strcat(temp+l, tt); + l+=strlen(tt); + } + strcat(temp+l, "R)"); + + free( string ); + + HIT = (char *) space(sizeof(char)*(strlen(temp)+2)); + strcpy(HIT, temp); + free(temp); + return(HIT); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char *b2C(const char *structure ) +{ + short *bulge, *loop; + + int i, lp, p, l; + char *string, *Coarse, *temp; + + bulge = (short *) space(sizeof(short)*(strlen(structure)/3+1)); + loop = (short *) space(sizeof(short)*(strlen(structure)/3+1)); + temp = (char *) space(4*strlen(structure)+2); + + for (i = 0; i < STRUC; i++) { + loop_size[i] = helix_size[i] = 0; + } + loop_degree[0]=0; /* open structure has degree 0 */ + pairs = unpaired = loops = lp = 0; + loop[0]=0; + + string = aux_struct( structure ); + + i=p=l=0; + temp[l++] = '('; + while (string[i]) { + switch(string[i]) { + case '.': + loop_size[loop[lp]]++; + break; + case '[': + temp[l++]='('; + if ((i>0)&&(string[i-1]=='(')) bulge[lp]=1; + lp++; + loop_degree[++loops]=1; + loop[lp]=loops; + bulge[lp]=0; + break; + case ')': + if (string[i-1]==']') bulge[lp]=1; + p++; + break; + case ']': + if (string[i-1]==']') bulge[lp]=1; + switch (loop_degree[loop[lp]]) { + case 1: temp[l++]='H'; break; /* hairpin */ + case 2: + if (bulge[lp]==1) + temp[l++] = 'B'; /* bulge */ + else + temp[l++] = 'I'; /* internal loop */ + break; + default: temp[l++] = 'M'; /* multiloop */ + } + temp[l++] = ')'; + pairs+=p+1; + p=0; + loop_degree[loop[--lp]]++; + break; + } + i++; + } + temp[l++] = 'R'; + temp[l++] = ')'; + temp[l]='\0'; + free(string); + Coarse = (char *) space(sizeof(char)*(strlen(temp)+2)); + strcpy(Coarse, temp); + free(temp); + free(bulge); free(loop); + return(Coarse); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char *b2Shapiro(const char *structure ) +{ + + short *bulge, *loop; + + int i, lp, p, l, k; + char *string, *Shapiro, *temp, tt[10]; + + bulge = (short *) space(sizeof(short)*(strlen(structure)/3+1)); + loop = (short *) space(sizeof(short)*(strlen(structure)/3+1)); + temp = (char *) space(4*strlen(structure)+3); + + for (i = 0; i < STRUC; i++) { + loop_size[i] = helix_size[i] = 0; + } + loop_degree[0]=0; /* open structure has degree 0 */ + pairs = unpaired = loops = lp = 0; + loop[0]=0; + + string = aux_struct( structure ); + + i=p=l=0; + temp[l++] = '('; /* root */ + while (string[i]) { + switch(string[i]) { + case '.': + unpaired++; + loop_size[loop[lp]]++; + break; + case '[': + temp[l++]='('; + temp[l++]='('; + if ((i>0)&&(string[i-1]=='(')) bulge[lp]=1; + lp++; + loop_degree[++loops]=1; + loop[lp]=loops; + bulge[lp]=0; + break; + case ')': + if (string[i-1]==']') bulge[lp]=1; + p++; + break; + case ']': + if (string[i-1]==']') bulge[lp]=1; + switch (loop_degree[loop[lp]]) { + case 1: temp[l++]='H'; break; /* hairpin */ + case 2: + if (bulge[lp]==1) + temp[l++] = 'B'; /* bulge */ + else + temp[l++] = 'I'; /* internal loop */ + break; + default: temp[l++] = 'M'; /* multiloop */ + } + helix_size[loop[lp]]=p+1; + + sprintf(tt, "%d)" , loop_size[loop[lp]]); + for(k=0; k0)&&(string[i-1]=='(')) bulge[lp]=1; + lp++; + loop_degree[++loops]=1; + loop[lp]=loops; + bulge[lp]=0; + break; + case ')': + if (string[i-1]==']') bulge[lp]=1; + p++; + break; + case ']': + if (string[i-1]==']') bulge[lp]=1; + helix_size[loop[lp]]=p+1; + pairs+=p+1; + p=0; + loop_degree[loop[--lp]]++; + break; + } + i++; + } + free(string); + free(bulge); free(loop); + free(temp); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char *add_root(const char *structure) +{ + char *xS; + xS = (char *) space(sizeof(char)*(strlen(structure)+4)); + xS[0] = '('; + strcat(xS,structure); + strcat(xS,"R)"); + return xS; +} + + +/*---------------------------------------------------------------------------*/ + +PUBLIC char *expand_Shapiro(const char *structure) +{ + char *xS, *temp; + int i, l; + + temp = (char *) space(4*strlen(structure)+2); + + i = 1; + l = 1; + temp[0] = '('; + while (i=0) { + switch (structure[i]) { + case '(': + for (j=0; j1xy02M`lBy&Sdwk;oo!#`CioA&(C2xfXENRv_13kP6`Y&#%1Lj{&bHGj z2^${*9Z#boaXWm-7kITbdyEwvnebH1n6}fY!3pc$Xgi%&Q&Y3ErSl#K;T5N!a+GP+RwU z+v%$lHtq$o?Q|J<)bhfnPkrr+k`vcegg$->RfExt{lb;JK-d@hL%!>C8Ntw7z`xby zYda9rzB7FG?AfngI{)B?4_cuFPlR4Na3b-mgRQNWm5}?AuRX`@OUQlJdd1iFmYwmb zFZHb)*Nar;!z+i(hBfBT# zD9lYeeSrhv0~`MFVo%FD60-@%0~U>3_bzlXjK-K`fMext%YsSIsdPu3`0(p+cuvOA zjH4Yej$!OV*XQhmVF<(YQFw*fP7dOFz`_T7ftOpev#gq(2^()mo~L56#2EeihTpaFFifeuNfO64-3 zFsI8Pt7%@(cfOk+`bu!AiQ38iL*SThy7MC#2GZ81qhL2>T|aDlN=xs&z+r6rT$i== z9N7Svf4>MH^aT#WBs?$}5-9Z|23N{$p*g#4SDSg910)W@XbF z^vf_u8enlr^tG=^_KFoIC;SWy$?(C@Krx25$_uS)zV`fNFXYGfo|xKmlfAg0`BD$~ zroNES_Dg6;!rt6TpzJs-`CxR`mY9hr?-s2I9}0`X1Dh4$AdMdpsn%==(x$f|Uu3>^ zfMRRYD+!x2FmBiinGo&4WN*!p+!!yeBQYbf#V}s5(J~Ww@bHoXi^*1DG(YquOjDco z2YdV4Z*XppVHTF|{xxe+{#}(pnbm1@eiVcOr;6 zf;BdAjmzq6!yBsGse?OzD@LVo*w^_ku!tUT_#ij_w^E{nQ{rVviROXbq{Gj)ib*w` zpFGf&58h)lAjK1TXodGXvup!pN#}##ViYixZQ0kjf_*91^Ewl-H8SyMb-JO#E2G>W z@az-0KI&^7X|j=ru7YQ|C6i~cL?qce}d6f{T79e;E%htii!m|3h7`~MaWXMCA) zRIZK*8#jV1%rXPTEE9%`S{H+LYDGk*b?=IKb+L!UA>;jO1Ov#;NX^UOUZDM%v`o#M*xj}8M($fD2a^a7hmQ@L_F0Xk$U}g}`UQ4Wq&ZdgMaYGu+YnH^^@^*g?uVKL9}N z_k5v6$*1x|RmrDe$w|r!eJh-AUll`*_-~jZVC&Ig$FJdzfL(pNqNlAqYUghM+r^+b%Xl)-Mbf93d zqEf-yNjQ%wAm!wz*iPf%sx=ArZm+aXgN5*L@G3ZRO_Jj+8_r!jME4&I9|Q|2u;qYD zY4{)}tHi+V1FhLfcwXHbla!s(@_W2J`-)}yclBjeHEnQnRe>SYd*;f91&V@QJdR&5{4rjojN}h>(Cn+M{(Qe zx7H03`9{W5@R5Ok>a*)l=7e9wf$YcCPYh)2D*5LN)g`}&t`aQiwJG?vmQ>S*z8t%LEtb!f5}{rON!%HIn6 z4~()rqQd4h)RC|^Zme%>4`0GlFMpX^;PT++y8{N(tSxaVut&%XywjRJ)@ph4ka?Q}uH#^DfxgdLlqzeOUtRt|^s8w{tD*;{g_!*UPJn;mXIMR0(k(Roe0E3fQaOZKumyZjtsUCCyBD>h-p-Q`Yor`#N=5*j2AV9PFOzV?3z_MZ!tUiM1F~H>-fZTY;vU>KFOtEiaW>Tp^%MB@WnLmksI;Kg+VhHRZ!C1StK4`_nN`crIR2#EnF}@0NCzA4J&sfhEuDE*i7%NcA zdefZ-XJp8!IM)KaJ<5{Rey$ru)g!C@shTLO1E`uLs{^U(mDO{onj))%sG2UT=TbFO zR+FeYQ&tC4)hDY%s9GSaL#et@R)@P*Kr`Hbb%jd({0@pX=Hs`1iOhk0;i15mb6%e_`%e_9H#8p;(gay)X~~dQ3LmlC^!Z zeA*_Kcr^k6fU*#*4_y zO4ru}aev%+Ap)acRMS|nU#;bufbL-F*PvG#wThHVzftm`a|J;5e-q4$QQ<274*NxH z9}Si&gDqNR02mZ^+$-by)oC}RaX%Y3s{MR{K){9YHIRSkPVRNN~Qu@}^he%ERhsr`NQ-@Vc! zwTl{RH>#pX-d8;`$OH4eY|LEkZ9EjDaxPw7lU>}DBvGH|;tnwD=Rs@o#CS!<^RNrF zYL}W6ov(su)~&&pEAQ626dUT*i}Y}f^6

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z#s1=#Z7=>#H~hip%u{*v%Y=LVtzCteb$JiqS9qd&{&V}Ej49{u}_KK8rT=h6S#=;OYAYZ*7ze|+8(?Zy3gQ6Bwb z;n2tW|MWci^Nc>$u>~ft */ +/* + global variables to change behaviour of folding routines + Vienna RNA package +*/ +#include +#include +#include "fold_vars.h" + +int noGU = 0; /* GU not allowed at all */ +int no_closingGU = 0; /* GU allowed only inside stacks */ +int tetra_loop = 1; /* Fold with specially stable 4-loops */ +int energy_set = 0; /* 0 = BP; 1=any with GC; 2=any with AU parameters */ +int dangles = 1; /* use dangling end energies */ +char *nonstandards = (char *)0; /* contains allowed non standard bases */ +double temperature = 37.0; +int james_rule = 1; /* interior loops of size 2 get energy 0.8Kcal and + no mismatches (no longer used) */ +struct bond *base_pair; + +FLT_OR_DBL *pr; /* base pairing prob. matrix */ +int *iindx; /* pr[i,j] -> pr[iindx[i]-j] */ +double pf_scale=- 1; /* scaling factor to avoid floating point overflows */ +int fold_constrained = 0; /* fold with constraints */ +int do_backtrack=1; /* calculate pair prob matrix in part_func() */ +int noLonelyPairs = 0; /* avoid helices of length 1 */ +char backtrack_type='F'; /* 'C' require (1,N) to be bonded; + 'M' seq is part of s multi loop */ + +char * option_string(void) { + static char options[100]; + *options = '\0'; + if (noGU) strcat(options, "-noGU "); + if (no_closingGU) strcat(options, "-noCloseGU "); + if (!tetra_loop) strcat(options, "-4 "); + if (noLonelyPairs) strcat(options, "-noLP "); + if (fold_constrained) strcat(options, "-C "); + if (dangles!=1) sprintf(options+strlen(options), "-d%d ", dangles); + if (temperature!=37.0) + sprintf(options+strlen(options), "-T %f ", temperature); + return options; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/fold_vars.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/fold_vars.o new file mode 100755 index 0000000000000000000000000000000000000000..1ec46656acbb56a1f038f93be5aac952c2d7dc3a GIT binary patch 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110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* CG..AU */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* CG..UA */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* CG..?? */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110} +} +}, +{ /* noPair */ {{0}}, +/* GC..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 40, 30, -10, 40}, +{ 110, -40, 50, 40, 0}, +{ 110, 40, 40, -170, 40}, +{ 110, 40, 50, 40, -30} +}, +/* GC..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 80, 40, 40, 40}, +{ 110, 40, 40, 40, 40}, +{ 110, 40, 40, -210, 40}, +{ 110, 40, 40, 40, -70} +}, +/* GC..GU */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* GC..UG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* GC..AU */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 100} +}, +/* GC..UA */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* GC..?? */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110} +} +}, +{ /* noPair */ {{0}}, +/* GU..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* GU..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* GU..GU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* GU..UG */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* GU..AU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* GU..UA */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* GU..?? */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +} +}, +{ /* noPair */ {{0}}, +/* UG..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* UG..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* UG..GU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UG..UG */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UG..AU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UG..UA */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UG..?? */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +} +}, +{ /* noPair */ {{0}}, +/* AU..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* AU..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 100} +}, +/* AU..GU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* AU..UG */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* AU..AU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 120} +}, +/* AU..UA */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 150} +}, +/* AU..?? */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +} +}, +{ /* noPair */ {{0}}, +/* UA..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* UA..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, -100, 110}, +{ 110, 110, 110, 110, 110} +}, +/* UA..GU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UA..UG */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 170} +}, +/* UA..AU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 150} +}, +/* UA..UA */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, -40, 170}, +{ 170, 170, 170, 170, 180} +}, +/* UA..?? */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +} +}, +{ /* noPair */ {{0}}, +/* ??..CG */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110} +}, +/* ??..GC */ +{{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110}, +{ 110, 110, 110, 110, 110} +}, +/* ??..GU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +}, +/* ??..UG */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +}, +/* ??..AU */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +}, +/* ??..UA */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +}, +/* ??..?? */ +{{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170}, +{ 170, 170, 170, 170, 170} +} +} +}; + +PUBLIC int int11_H[NBPAIRS+1][NBPAIRS+1][5][5] = + /* GC..GC */ +{ /* noPair */ {{{0}}}, +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GC.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* CG..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* CG.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* GU..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* GU.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* UG..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UG.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* AU..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* AU.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* UA..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* UA.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}, + /* @..GC */ +{ /* noPair */ {{0}}, +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @..CG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @..GU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @..UG */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @..AU */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @..UA */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}, + /* @.. @ */ +{ { 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}, +{ 0, 0, 0, 0, 0}}}}; + +PUBLIC int int21_37[NBPAIRS+1][NBPAIRS+1][5][5][5] = +{ /* noPair */ {{{{0}}}}, +{ /* noPair */ {{{0}}}, +{ +/* CG.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 240, 220, 160, 400},{ 550, 210, 170, 160, 400},{ 550, 100, 60, 40, 400},{ 550, 400, 400, 400, 400}}, +/* CG.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 230, 220, 400, 220},{ 550, 220, 250, 400, 220},{ 550, 400, 400, 400, 400},{ 550, 250, 190, 400, 220}}, +/* CG.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 170, 400, 80, 400},{ 550, 400, 400, 400, 400},{ 550, 80, 400, 220, 400},{ 550, 400, 400, 400, 400}}, +/* CG.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 400, 400, 400, 400},{ 550, 400, 220, 400, 130},{ 550, 400, 400, 400, 400},{ 550, 400, 170, 400, 120}} +}, +{ +/* CG.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 230, 220, 110, 400},{ 550, 210, 170, 160, 400},{ 550, 80, 60, 40, 400},{ 550, 400, 400, 400, 400}}, +/* CG.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 230, 220, 400, 220},{ 550, 220, 250, 400, 220},{ 550, 400, 400, 400, 400},{ 550, 250, 190, 400, 220}}, +/* CG.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 170, 400, 80, 400},{ 550, 400, 400, 400, 400},{ 550, 80, 400, 220, 400},{ 550, 400, 400, 400, 400}}, +/* CG.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 400, 400, 400, 400},{ 550, 400, 220, 400, 150},{ 550, 400, 400, 400, 400},{ 550, 400, 170, 400, 120}} +}, +{ +/* CG.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* CG.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* CG.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* CG.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* CG.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* CG.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* CG.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* CG.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* CG.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* CG.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* CG.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* CG.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* CG.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* CG.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* CG.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* CG.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* CG.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* CG.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* GC.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 220, 210, 400},{ 550, 210, 170, 160, 400},{ 550, 120, 60, 40, 400},{ 550, 400, 400, 400, 400}}, +/* GC.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 230, 220, 400, 220},{ 550, 220, 250, 400, 220},{ 550, 400, 400, 400, 400},{ 550, 250, 190, 400, 220}}, +/* GC.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 170, 400, 80, 400},{ 550, 400, 400, 400, 400},{ 550, 80, 400, 220, 400},{ 550, 400, 400, 400, 400}}, +/* GC.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 400, 400, 400, 400},{ 550, 400, 220, 400, 120},{ 550, 400, 400, 400, 400},{ 550, 400, 170, 400, 120}} +}, +{ +/* GC.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 240, 220, 160, 400},{ 550, 210, 170, 160, 400},{ 550, 100, 60, 40, 400},{ 550, 400, 400, 400, 400}}, +/* GC.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 230, 220, 400, 220},{ 550, 220, 250, 400, 220},{ 550, 400, 400, 400, 400},{ 550, 250, 190, 400, 220}}, +/* GC.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 170, 400, 80, 400},{ 550, 400, 400, 400, 400},{ 550, 80, 400, 220, 400},{ 550, 400, 400, 400, 400}}, +/* GC.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 400, 400, 400, 400},{ 550, 400, 220, 400, 130},{ 550, 400, 400, 400, 400},{ 550, 400, 170, 400, 120}} +}, +{ +/* GC.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GC.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GC.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GC.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GC.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GC.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GC.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GC.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GC.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GC.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GC.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GC.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GC.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GC.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GC.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GC.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GC.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GC.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* GU.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GU.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GU.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GU.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GU.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* GU.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* GU.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* GU.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* GU.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* GU.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* GU.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* GU.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* GU.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* GU.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* GU.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* GU.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* GU.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* GU.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* GU.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* GU.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* GU.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* GU.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* GU.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* GU.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* GU.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* GU.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* UG.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* UG.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* UG.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* UG.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* UG.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* UG.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* UG.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* UG.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* UG.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UG.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UG.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UG.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UG.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UG.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UG.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UG.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UG.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UG.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UG.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UG.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UG.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UG.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UG.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UG.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UG.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UG.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* AU.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* AU.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* AU.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* AU.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* AU.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* AU.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* AU.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* AU.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* AU.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* AU.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* AU.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* AU.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* AU.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* AU.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* AU.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* AU.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* AU.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* AU.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* AU.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* AU.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* AU.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* AU.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* AU.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* AU.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* AU.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* AU.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* UA.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* UA.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* UA.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* UA.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* UA.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 300, 240, 480},{ 550, 290, 250, 240, 480},{ 550, 180, 140, 120, 480},{ 550, 480, 480, 480, 480}}, +/* UA.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 310, 300, 480, 300},{ 550, 300, 330, 480, 300},{ 550, 480, 480, 480, 480},{ 550, 330, 270, 480, 300}}, +/* UA.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 250, 480, 160, 480},{ 550, 480, 480, 480, 480},{ 550, 160, 480, 300, 480},{ 550, 480, 480, 480, 480}}, +/* UA.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 480, 480, 480, 480},{ 550, 480, 300, 480, 210},{ 550, 480, 480, 480, 480},{ 550, 480, 250, 480, 200}} +}, +{ +/* UA.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UA.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UA.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UA.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UA.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UA.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UA.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UA.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UA.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UA.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UA.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UA.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UA.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 390, 370, 310, 550},{ 550, 360, 320, 310, 550},{ 550, 250, 210, 190, 550},{ 550, 550, 550, 550, 550}}, +/* UA.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 380, 370, 550, 370},{ 550, 370, 400, 550, 370},{ 550, 550, 550, 550, 550},{ 550, 400, 340, 550, 370}}, +/* UA.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 320, 550, 230, 550},{ 550, 550, 550, 550, 550},{ 550, 230, 550, 370, 550},{ 550, 550, 550, 550, 550}}, +/* UA.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 370, 550, 280},{ 550, 550, 550, 550, 550},{ 550, 550, 320, 550, 270}} +}, +{ +/* UA.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* UA.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* ??.@..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..GC */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..CG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..UG */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..GU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..UA */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..AU */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +}, +{ +/* ??.@..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.A..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.C..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.G..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}}, +/* ??.U..?? */ +{{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550},{ 550, 550, 550, 550, 550}} +} +} +}; + +PUBLIC int int21_H[NBPAIRS+1][NBPAIRS+1][5][5][5] = +{ /* noPair */ {{{{0}}}}, +{ /* noPair */ {{{0}}}, +{ +/* CG.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..CG */ +{{ DEF,-1029, -949,-1029,-1029},{-1079,-2058,-1978,-2058,-2058},{ -569,-1548,-1468,-1548,-1548},{ -989,-1968,-1888,-1968,-1968},{ -859,-1838,-1758,-1838,-1838}}, +/* CG.C..CG */ +{{ DEF, -519, -449, -519, -669},{ -999,-1468,-1398,-1468,-1618},{ -499, -968, -898, -968,-1118},{ -989,-1458,-1388,-1458,-1608},{ -789,-1258,-1188,-1258,-1408}}, +/* CG.G..CG */ +{{ DEF, -939, -939, -939, -939},{-1079,-1968,-1968,-1968,-1968},{ -569,-1458,-1458,-1458,-1458},{ -989,-1878,-1878,-1878,-1878},{ -859,-1748,-1748,-1748,-1748}}, +/* CG.U..CG */ +{{ DEF, -809, -739, -809, -859},{-1079,-1838,-1768,-1838,-1888},{ -719,-1478,-1408,-1478,-1528},{ -989,-1748,-1678,-1748,-1798},{ -909,-1668,-1598,-1668,-1718}} +}, +{ +/* CG.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..GC */ +{{ DEF,-1029, -949,-1029,-1029},{ -569,-1548,-1468,-1548,-1548},{ -769,-1748,-1668,-1748,-1748},{ -759,-1738,-1658,-1738,-1738},{ -549,-1528,-1448,-1528,-1528}}, +/* CG.C..GC */ +{{ DEF, -519, -449, -519, -669},{ -929,-1398,-1328,-1398,-1548},{ -359, -828, -758, -828, -978},{ -789,-1258,-1188,-1258,-1408},{ -549,-1018, -948,-1018,-1168}}, +/* CG.G..GC */ +{{ DEF, -939, -939, -939, -939},{ -609,-1498,-1498,-1498,-1498},{ -359,-1248,-1248,-1248,-1248},{ -669,-1558,-1558,-1558,-1558},{ -549,-1438,-1438,-1438,-1438}}, +/* CG.U..GC */ +{{ DEF, -809, -739, -809, -859},{ -929,-1688,-1618,-1688,-1738},{ -439,-1198,-1128,-1198,-1248},{ -789,-1548,-1478,-1548,-1598},{ -619,-1378,-1308,-1378,-1428}} +}, +{ +/* CG.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..GU */ +{{ DEF,-1029, -949,-1029,-1029},{ -479,-1458,-1378,-1458,-1458},{ -309,-1288,-1208,-1288,-1288},{ -389,-1368,-1288,-1368,-1368},{ -379,-1358,-1278,-1358,-1358}}, +/* CG.C..GU */ +{{ DEF, -519, -449, -519, -669},{ -649,-1118,-1048,-1118,-1268},{ -289, -758, -688, -758, -908},{ -739,-1208,-1138,-1208,-1358},{ -379, -848, -778, -848, -998}}, +/* CG.G..GU */ +{{ DEF, -939, -939, -939, -939},{ -649,-1538,-1538,-1538,-1538},{ -289,-1178,-1178,-1178,-1178},{ -739,-1628,-1628,-1628,-1628},{ -379,-1268,-1268,-1268,-1268}}, +/* CG.U..GU */ +{{ DEF, -809, -739, -809, -859},{ -649,-1408,-1338,-1408,-1458},{ -289,-1048, -978,-1048,-1098},{ -739,-1498,-1428,-1498,-1548},{ -379,-1138,-1068,-1138,-1188}} +}, +{ +/* CG.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..UG */ +{{ DEF,-1029, -949,-1029,-1029},{ -769,-1748,-1668,-1748,-1748},{ -529,-1508,-1428,-1508,-1508},{ -709,-1688,-1608,-1688,-1688},{ -599,-1578,-1498,-1578,-1578}}, +/* CG.C..UG */ +{{ DEF, -519, -449, -519, -669},{ -839,-1308,-1238,-1308,-1458},{ -529, -998, -928, -998,-1148},{ -859,-1328,-1258,-1328,-1478},{ -489, -958, -888, -958,-1108}}, +/* CG.G..UG */ +{{ DEF, -939, -939, -939, -939},{-1009,-1898,-1898,-1898,-1898},{ -409,-1298,-1298,-1298,-1298},{ -969,-1858,-1858,-1858,-1858},{ -599,-1488,-1488,-1488,-1488}}, +/* CG.U..UG */ +{{ DEF, -809, -739, -809, -859},{ -859,-1618,-1548,-1618,-1668},{ -529,-1288,-1218,-1288,-1338},{ -859,-1618,-1548,-1618,-1668},{ -409,-1168,-1098,-1168,-1218}} +}, +{ +/* CG.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..AU */ +{{ DEF,-1029, -949,-1029,-1029},{ -479,-1458,-1378,-1458,-1458},{ -309,-1288,-1208,-1288,-1288},{ -389,-1368,-1288,-1368,-1368},{ -379,-1358,-1278,-1358,-1358}}, +/* CG.C..AU */ +{{ DEF, -519, -449, -519, -669},{ -649,-1118,-1048,-1118,-1268},{ -289, -758, -688, -758, -908},{ -739,-1208,-1138,-1208,-1358},{ -379, -848, -778, -848, -998}}, +/* CG.G..AU */ +{{ DEF, -939, -939, -939, -939},{ -649,-1538,-1538,-1538,-1538},{ -289,-1178,-1178,-1178,-1178},{ -739,-1628,-1628,-1628,-1628},{ -379,-1268,-1268,-1268,-1268}}, +/* CG.U..AU */ +{{ DEF, -809, -739, -809, -859},{ -649,-1408,-1338,-1408,-1458},{ -289,-1048, -978,-1048,-1098},{ -739,-1498,-1428,-1498,-1548},{ -379,-1138,-1068,-1138,-1188}} +}, +{ +/* CG.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A..UA */ +{{ DEF,-1029, -949,-1029,-1029},{ -449,-1428,-1348,-1428,-1428},{ -479,-1458,-1378,-1458,-1458},{ -429,-1408,-1328,-1408,-1408},{ -329,-1308,-1228,-1308,-1308}}, +/* CG.C..UA */ +{{ DEF, -519, -449, -519, -669},{ -679,-1148,-1078,-1148,-1298},{ -559,-1028, -958,-1028,-1178},{ -729,-1198,-1128,-1198,-1348},{ -189, -658, -588, -658, -808}}, +/* CG.G..UA */ +{{ DEF, -939, -939, -939, -939},{ -939,-1828,-1828,-1828,-1828},{ -249,-1138,-1138,-1138,-1138},{ -939,-1828,-1828,-1828,-1828},{ -329,-1218,-1218,-1218,-1218}}, +/* CG.U..UA */ +{{ DEF, -809, -739, -809, -859},{ -639,-1398,-1328,-1398,-1448},{ -229, -988, -918, -988,-1038},{ -729,-1488,-1418,-1488,-1538},{ -190, -949, -879, -949, -999}} +}, +{ +/* CG.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.A.. @ */ +{{ -100,-1079, -999,-1079,-1079},{ -100,-1079, -999,-1079,-1079},{ -100,-1079, -999,-1079,-1079},{ -100,-1079, -999,-1079,-1079},{ -100,-1079, -999,-1079,-1079}}, +/* CG.C.. @ */ +{{ -100, -569, -499, -569, -719},{ -100, -569, -499, -569, -719},{ -100, -569, -499, -569, -719},{ -100, -569, -499, -569, -719},{ -100, -569, -499, -569, -719}}, +/* CG.G.. @ */ +{{ -100, -989, -989, -989, -989},{ -100, -989, -989, -989, -989},{ -100, -989, -989, -989, -989},{ -100, -989, -989, -989, -989},{ -100, -989, -989, -989, -989}}, +/* CG.U.. @ */ +{{ -100, -859, -789, -859, -909},{ -100, -859, -789, -859, -909},{ -100, -859, -789, -859, -909},{ -100, -859, -789, -859, -909},{ -100, -859, -789, -859, -909}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* GC.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..CG */ +{{ DEF, -519, -879, -559, -879},{-1079,-1548,-1908,-1588,-1908},{ -569,-1038,-1398,-1078,-1398},{ -989,-1458,-1818,-1498,-1818},{ -859,-1328,-1688,-1368,-1688}}, +/* GC.C..CG */ +{{ DEF, -719, -309, -309, -389},{ -999,-1668,-1258,-1258,-1338},{ -499,-1168, -758, -758, -838},{ -989,-1658,-1248,-1248,-1328},{ -789,-1458,-1048,-1048,-1128}}, +/* GC.G..CG */ +{{ DEF, -709, -739, -619, -739},{-1079,-1738,-1768,-1648,-1768},{ -569,-1228,-1258,-1138,-1258},{ -989,-1648,-1678,-1558,-1678},{ -859,-1518,-1548,-1428,-1548}}, +/* GC.U..CG */ +{{ DEF, -499, -499, -499, -569},{-1079,-1528,-1528,-1528,-1598},{ -719,-1168,-1168,-1168,-1238},{ -989,-1438,-1438,-1438,-1508},{ -909,-1358,-1358,-1358,-1428}} +}, +{ +/* GC.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..GC */ +{{ DEF, -519, -879, -559, -879},{ -569,-1038,-1398,-1078,-1398},{ -769,-1238,-1598,-1278,-1598},{ -759,-1228,-1588,-1268,-1588},{ -549,-1018,-1378,-1058,-1378}}, +/* GC.C..GC */ +{{ DEF, -719, -309, -309, -389},{ -929,-1598,-1188,-1188,-1268},{ -359,-1028, -618, -618, -698},{ -789,-1458,-1048,-1048,-1128},{ -549,-1218, -808, -808, -888}}, +/* GC.G..GC */ +{{ DEF, -709, -739, -619, -739},{ -609,-1268,-1298,-1178,-1298},{ -359,-1018,-1048, -928,-1048},{ -669,-1328,-1358,-1238,-1358},{ -549,-1208,-1238,-1118,-1238}}, +/* GC.U..GC */ +{{ DEF, -499, -499, -499, -569},{ -929,-1378,-1378,-1378,-1448},{ -439, -888, -888, -888, -958},{ -789,-1238,-1238,-1238,-1308},{ -619,-1068,-1068,-1068,-1138}} +}, +{ +/* GC.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..GU */ +{{ DEF, -519, -879, -559, -879},{ -479, -948,-1308, -988,-1308},{ -309, -778,-1138, -818,-1138},{ -389, -858,-1218, -898,-1218},{ -379, -848,-1208, -888,-1208}}, +/* GC.C..GU */ +{{ DEF, -719, -309, -309, -389},{ -649,-1318, -908, -908, -988},{ -289, -958, -548, -548, -628},{ -739,-1408, -998, -998,-1078},{ -379,-1048, -638, -638, -718}}, +/* GC.G..GU */ +{{ DEF, -709, -739, -619, -739},{ -649,-1308,-1338,-1218,-1338},{ -289, -948, -978, -858, -978},{ -739,-1398,-1428,-1308,-1428},{ -379,-1038,-1068, -948,-1068}}, +/* GC.U..GU */ +{{ DEF, -499, -499, -499, -569},{ -649,-1098,-1098,-1098,-1168},{ -289, -738, -738, -738, -808},{ -739,-1188,-1188,-1188,-1258},{ -379, -828, -828, -828, -898}} +}, +{ +/* GC.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..UG */ +{{ DEF, -519, -879, -559, -879},{ -769,-1238,-1598,-1278,-1598},{ -529, -998,-1358,-1038,-1358},{ -709,-1178,-1538,-1218,-1538},{ -599,-1068,-1428,-1108,-1428}}, +/* GC.C..UG */ +{{ DEF, -719, -309, -309, -389},{ -839,-1508,-1098,-1098,-1178},{ -529,-1198, -788, -788, -868},{ -859,-1528,-1118,-1118,-1198},{ -489,-1158, -748, -748, -828}}, +/* GC.G..UG */ +{{ DEF, -709, -739, -619, -739},{-1009,-1668,-1698,-1578,-1698},{ -409,-1068,-1098, -978,-1098},{ -969,-1628,-1658,-1538,-1658},{ -599,-1258,-1288,-1168,-1288}}, +/* GC.U..UG */ +{{ DEF, -499, -499, -499, -569},{ -859,-1308,-1308,-1308,-1378},{ -529, -978, -978, -978,-1048},{ -859,-1308,-1308,-1308,-1378},{ -409, -858, -858, -858, -928}} +}, +{ +/* GC.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..AU */ +{{ DEF, -519, -879, -559, -879},{ -479, -948,-1308, -988,-1308},{ -309, -778,-1138, -818,-1138},{ -389, -858,-1218, -898,-1218},{ -379, -848,-1208, -888,-1208}}, +/* GC.C..AU */ +{{ DEF, -719, -309, -309, -389},{ -649,-1318, -908, -908, -988},{ -289, -958, -548, -548, -628},{ -739,-1408, -998, -998,-1078},{ -379,-1048, -638, -638, -718}}, +/* GC.G..AU */ +{{ DEF, -709, -739, -619, -739},{ -649,-1308,-1338,-1218,-1338},{ -289, -948, -978, -858, -978},{ -739,-1398,-1428,-1308,-1428},{ -379,-1038,-1068, -948,-1068}}, +/* GC.U..AU */ +{{ DEF, -499, -499, -499, -569},{ -649,-1098,-1098,-1098,-1168},{ -289, -738, -738, -738, -808},{ -739,-1188,-1188,-1188,-1258},{ -379, -828, -828, -828, -898}} +}, +{ +/* GC.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A..UA */ +{{ DEF, -519, -879, -559, -879},{ -449, -918,-1278, -958,-1278},{ -479, -948,-1308, -988,-1308},{ -429, -898,-1258, -938,-1258},{ -329, -798,-1158, -838,-1158}}, +/* GC.C..UA */ +{{ DEF, -719, -309, -309, -389},{ -679,-1348, -938, -938,-1018},{ -559,-1228, -818, -818, -898},{ -729,-1398, -988, -988,-1068},{ -189, -858, -448, -448, -528}}, +/* GC.G..UA */ +{{ DEF, -709, -739, -619, -739},{ -939,-1598,-1628,-1508,-1628},{ -249, -908, -938, -818, -938},{ -939,-1598,-1628,-1508,-1628},{ -329, -988,-1018, -898,-1018}}, +/* GC.U..UA */ +{{ DEF, -499, -499, -499, -569},{ -639,-1088,-1088,-1088,-1158},{ -229, -678, -678, -678, -748},{ -729,-1178,-1178,-1178,-1248},{ -190, -639, -639, -639, -709}} +}, +{ +/* GC.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.A.. @ */ +{{ -100, -569, -929, -609, -929},{ -100, -569, -929, -609, -929},{ -100, -569, -929, -609, -929},{ -100, -569, -929, -609, -929},{ -100, -569, -929, -609, -929}}, +/* GC.C.. @ */ +{{ -100, -769, -359, -359, -439},{ -100, -769, -359, -359, -439},{ -100, -769, -359, -359, -439},{ -100, -769, -359, -359, -439},{ -100, -769, -359, -359, -439}}, +/* GC.G.. @ */ +{{ -100, -759, -789, -669, -789},{ -100, -759, -789, -669, -789},{ -100, -759, -789, -669, -789},{ -100, -759, -789, -669, -789},{ -100, -759, -789, -669, -789}}, +/* GC.U.. @ */ +{{ -100, -549, -549, -549, -619},{ -100, -549, -549, -549, -619},{ -100, -549, -549, -549, -619},{ -100, -549, -549, -549, -619},{ -100, -549, -549, -549, -619}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* GU.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..CG */ +{{ DEF, -429, -599, -599, -599},{-1079,-1458,-1628,-1628,-1628},{ -569, -948,-1118,-1118,-1118},{ -989,-1368,-1538,-1538,-1538},{ -859,-1238,-1408,-1408,-1408}}, +/* GU.C..CG */ +{{ DEF, -259, -239, -239, -239},{ -999,-1208,-1188,-1188,-1188},{ -499, -708, -688, -688, -688},{ -989,-1198,-1178,-1178,-1178},{ -789, -998, -978, -978, -978}}, +/* GU.G..CG */ +{{ DEF, -339, -689, -689, -689},{-1079,-1368,-1718,-1718,-1718},{ -569, -858,-1208,-1208,-1208},{ -989,-1278,-1628,-1628,-1628},{ -859,-1148,-1498,-1498,-1498}}, +/* GU.U..CG */ +{{ DEF, -329, -329, -329, -329},{-1079,-1358,-1358,-1358,-1358},{ -719, -998, -998, -998, -998},{ -989,-1268,-1268,-1268,-1268},{ -909,-1188,-1188,-1188,-1188}} +}, +{ +/* GU.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..GC */ +{{ DEF, -429, -599, -599, -599},{ -569, -948,-1118,-1118,-1118},{ -769,-1148,-1318,-1318,-1318},{ -759,-1138,-1308,-1308,-1308},{ -549, -928,-1098,-1098,-1098}}, +/* GU.C..GC */ +{{ DEF, -259, -239, -239, -239},{ -929,-1138,-1118,-1118,-1118},{ -359, -568, -548, -548, -548},{ -789, -998, -978, -978, -978},{ -549, -758, -738, -738, -738}}, +/* GU.G..GC */ +{{ DEF, -339, -689, -689, -689},{ -609, -898,-1248,-1248,-1248},{ -359, -648, -998, -998, -998},{ -669, -958,-1308,-1308,-1308},{ -549, -838,-1188,-1188,-1188}}, +/* GU.U..GC */ +{{ DEF, -329, -329, -329, -329},{ -929,-1208,-1208,-1208,-1208},{ -439, -718, -718, -718, -718},{ -789,-1068,-1068,-1068,-1068},{ -619, -898, -898, -898, -898}} +}, +{ +/* GU.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..GU */ +{{ DEF, -429, -599, -599, -599},{ -479, -858,-1028,-1028,-1028},{ -309, -688, -858, -858, -858},{ -389, -768, -938, -938, -938},{ -379, -758, -928, -928, -928}}, +/* GU.C..GU */ +{{ DEF, -259, -239, -239, -239},{ -649, -858, -838, -838, -838},{ -289, -498, -478, -478, -478},{ -739, -948, -928, -928, -928},{ -379, -588, -568, -568, -568}}, +/* GU.G..GU */ +{{ DEF, -339, -689, -689, -689},{ -649, -938,-1288,-1288,-1288},{ -289, -578, -928, -928, -928},{ -739,-1028,-1378,-1378,-1378},{ -379, -668,-1018,-1018,-1018}}, +/* GU.U..GU */ +{{ DEF, -329, -329, -329, -329},{ -649, -928, -928, -928, -928},{ -289, -568, -568, -568, -568},{ -739,-1018,-1018,-1018,-1018},{ -379, -658, -658, -658, -658}} +}, +{ +/* GU.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..UG */ +{{ DEF, -429, -599, -599, -599},{ -769,-1148,-1318,-1318,-1318},{ -529, -908,-1078,-1078,-1078},{ -709,-1088,-1258,-1258,-1258},{ -599, -978,-1148,-1148,-1148}}, +/* GU.C..UG */ +{{ DEF, -259, -239, -239, -239},{ -839,-1048,-1028,-1028,-1028},{ -529, -738, -718, -718, -718},{ -859,-1068,-1048,-1048,-1048},{ -489, -698, -678, -678, -678}}, +/* GU.G..UG */ +{{ DEF, -339, -689, -689, -689},{-1009,-1298,-1648,-1648,-1648},{ -409, -698,-1048,-1048,-1048},{ -969,-1258,-1608,-1608,-1608},{ -599, -888,-1238,-1238,-1238}}, +/* GU.U..UG */ +{{ DEF, -329, -329, -329, -329},{ -859,-1138,-1138,-1138,-1138},{ -529, -808, -808, -808, -808},{ -859,-1138,-1138,-1138,-1138},{ -409, -688, -688, -688, -688}} +}, +{ +/* GU.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..AU */ +{{ DEF, -429, -599, -599, -599},{ -479, -858,-1028,-1028,-1028},{ -309, -688, -858, -858, -858},{ -389, -768, -938, -938, -938},{ -379, -758, -928, -928, -928}}, +/* GU.C..AU */ +{{ DEF, -259, -239, -239, -239},{ -649, -858, -838, -838, -838},{ -289, -498, -478, -478, -478},{ -739, -948, -928, -928, -928},{ -379, -588, -568, -568, -568}}, +/* GU.G..AU */ +{{ DEF, -339, -689, -689, -689},{ -649, -938,-1288,-1288,-1288},{ -289, -578, -928, -928, -928},{ -739,-1028,-1378,-1378,-1378},{ -379, -668,-1018,-1018,-1018}}, +/* GU.U..AU */ +{{ DEF, -329, -329, -329, -329},{ -649, -928, -928, -928, -928},{ -289, -568, -568, -568, -568},{ -739,-1018,-1018,-1018,-1018},{ -379, -658, -658, -658, -658}} +}, +{ +/* GU.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A..UA */ +{{ DEF, -429, -599, -599, -599},{ -449, -828, -998, -998, -998},{ -479, -858,-1028,-1028,-1028},{ -429, -808, -978, -978, -978},{ -329, -708, -878, -878, -878}}, +/* GU.C..UA */ +{{ DEF, -259, -239, -239, -239},{ -679, -888, -868, -868, -868},{ -559, -768, -748, -748, -748},{ -729, -938, -918, -918, -918},{ -189, -398, -378, -378, -378}}, +/* GU.G..UA */ +{{ DEF, -339, -689, -689, -689},{ -939,-1228,-1578,-1578,-1578},{ -249, -538, -888, -888, -888},{ -939,-1228,-1578,-1578,-1578},{ -329, -618, -968, -968, -968}}, +/* GU.U..UA */ +{{ DEF, -329, -329, -329, -329},{ -639, -918, -918, -918, -918},{ -229, -508, -508, -508, -508},{ -729,-1008,-1008,-1008,-1008},{ -190, -469, -469, -469, -469}} +}, +{ +/* GU.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.A.. @ */ +{{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649}}, +/* GU.C.. @ */ +{{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289}}, +/* GU.G.. @ */ +{{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739}}, +/* GU.U.. @ */ +{{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* UG.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..CG */ +{{ DEF, -719, -789, -959, -809},{-1079,-1748,-1818,-1988,-1838},{ -569,-1238,-1308,-1478,-1328},{ -989,-1658,-1728,-1898,-1748},{ -859,-1528,-1598,-1768,-1618}}, +/* UG.C..CG */ +{{ DEF, -479, -479, -359, -479},{ -999,-1428,-1428,-1308,-1428},{ -499, -928, -928, -808, -928},{ -989,-1418,-1418,-1298,-1418},{ -789,-1218,-1218,-1098,-1218}}, +/* UG.G..CG */ +{{ DEF, -659, -809, -919, -809},{-1079,-1688,-1838,-1948,-1838},{ -569,-1178,-1328,-1438,-1328},{ -989,-1598,-1748,-1858,-1748},{ -859,-1468,-1618,-1728,-1618}}, +/* UG.U..CG */ +{{ DEF, -549, -439, -549, -359},{-1079,-1578,-1468,-1578,-1388},{ -719,-1218,-1108,-1218,-1028},{ -989,-1488,-1378,-1488,-1298},{ -909,-1408,-1298,-1408,-1218}} +}, +{ +/* UG.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..GC */ +{{ DEF, -719, -789, -959, -809},{ -569,-1238,-1308,-1478,-1328},{ -769,-1438,-1508,-1678,-1528},{ -759,-1428,-1498,-1668,-1518},{ -549,-1218,-1288,-1458,-1308}}, +/* UG.C..GC */ +{{ DEF, -479, -479, -359, -479},{ -929,-1358,-1358,-1238,-1358},{ -359, -788, -788, -668, -788},{ -789,-1218,-1218,-1098,-1218},{ -549, -978, -978, -858, -978}}, +/* UG.G..GC */ +{{ DEF, -659, -809, -919, -809},{ -609,-1218,-1368,-1478,-1368},{ -359, -968,-1118,-1228,-1118},{ -669,-1278,-1428,-1538,-1428},{ -549,-1158,-1308,-1418,-1308}}, +/* UG.U..GC */ +{{ DEF, -549, -439, -549, -359},{ -929,-1428,-1318,-1428,-1238},{ -439, -938, -828, -938, -748},{ -789,-1288,-1178,-1288,-1098},{ -619,-1118,-1008,-1118, -928}} +}, +{ +/* UG.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..GU */ +{{ DEF, -719, -789, -959, -809},{ -479,-1148,-1218,-1388,-1238},{ -309, -978,-1048,-1218,-1068},{ -389,-1058,-1128,-1298,-1148},{ -379,-1048,-1118,-1288,-1138}}, +/* UG.C..GU */ +{{ DEF, -479, -479, -359, -479},{ -649,-1078,-1078, -958,-1078},{ -289, -718, -718, -598, -718},{ -739,-1168,-1168,-1048,-1168},{ -379, -808, -808, -688, -808}}, +/* UG.G..GU */ +{{ DEF, -659, -809, -919, -809},{ -649,-1258,-1408,-1518,-1408},{ -289, -898,-1048,-1158,-1048},{ -739,-1348,-1498,-1608,-1498},{ -379, -988,-1138,-1248,-1138}}, +/* UG.U..GU */ +{{ DEF, -549, -439, -549, -359},{ -649,-1148,-1038,-1148, -958},{ -289, -788, -678, -788, -598},{ -739,-1238,-1128,-1238,-1048},{ -379, -878, -768, -878, -688}} +}, +{ +/* UG.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..UG */ +{{ DEF, -719, -789, -959, -809},{ -769,-1438,-1508,-1678,-1528},{ -529,-1198,-1268,-1438,-1288},{ -709,-1378,-1448,-1618,-1468},{ -599,-1268,-1338,-1508,-1358}}, +/* UG.C..UG */ +{{ DEF, -479, -479, -359, -479},{ -839,-1268,-1268,-1148,-1268},{ -529, -958, -958, -838, -958},{ -859,-1288,-1288,-1168,-1288},{ -489, -918, -918, -798, -918}}, +/* UG.G..UG */ +{{ DEF, -659, -809, -919, -809},{-1009,-1618,-1768,-1878,-1768},{ -409,-1018,-1168,-1278,-1168},{ -969,-1578,-1728,-1838,-1728},{ -599,-1208,-1358,-1468,-1358}}, +/* UG.U..UG */ +{{ DEF, -549, -439, -549, -359},{ -859,-1358,-1248,-1358,-1168},{ -529,-1028, -918,-1028, -838},{ -859,-1358,-1248,-1358,-1168},{ -409, -908, -798, -908, -718}} +}, +{ +/* UG.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..AU */ +{{ DEF, -719, -789, -959, -809},{ -479,-1148,-1218,-1388,-1238},{ -309, -978,-1048,-1218,-1068},{ -389,-1058,-1128,-1298,-1148},{ -379,-1048,-1118,-1288,-1138}}, +/* UG.C..AU */ +{{ DEF, -479, -479, -359, -479},{ -649,-1078,-1078, -958,-1078},{ -289, -718, -718, -598, -718},{ -739,-1168,-1168,-1048,-1168},{ -379, -808, -808, -688, -808}}, +/* UG.G..AU */ +{{ DEF, -659, -809, -919, -809},{ -649,-1258,-1408,-1518,-1408},{ -289, -898,-1048,-1158,-1048},{ -739,-1348,-1498,-1608,-1498},{ -379, -988,-1138,-1248,-1138}}, +/* UG.U..AU */ +{{ DEF, -549, -439, -549, -359},{ -649,-1148,-1038,-1148, -958},{ -289, -788, -678, -788, -598},{ -739,-1238,-1128,-1238,-1048},{ -379, -878, -768, -878, -688}} +}, +{ +/* UG.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A..UA */ +{{ DEF, -719, -789, -959, -809},{ -449,-1118,-1188,-1358,-1208},{ -479,-1148,-1218,-1388,-1238},{ -429,-1098,-1168,-1338,-1188},{ -329, -998,-1068,-1238,-1088}}, +/* UG.C..UA */ +{{ DEF, -479, -479, -359, -479},{ -679,-1108,-1108, -988,-1108},{ -559, -988, -988, -868, -988},{ -729,-1158,-1158,-1038,-1158},{ -189, -618, -618, -498, -618}}, +/* UG.G..UA */ +{{ DEF, -659, -809, -919, -809},{ -939,-1548,-1698,-1808,-1698},{ -249, -858,-1008,-1118,-1008},{ -939,-1548,-1698,-1808,-1698},{ -329, -938,-1088,-1198,-1088}}, +/* UG.U..UA */ +{{ DEF, -549, -439, -549, -359},{ -639,-1138,-1028,-1138, -948},{ -229, -728, -618, -728, -538},{ -729,-1228,-1118,-1228,-1038},{ -190, -689, -579, -689, -499}} +}, +{ +/* UG.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.A.. @ */ +{{ -100, -769, -839,-1009, -859},{ -100, -769, -839,-1009, -859},{ -100, -769, -839,-1009, -859},{ -100, -769, -839,-1009, -859},{ -100, -769, -839,-1009, -859}}, +/* UG.C.. @ */ +{{ -100, -529, -529, -409, -529},{ -100, -529, -529, -409, -529},{ -100, -529, -529, -409, -529},{ -100, -529, -529, -409, -529},{ -100, -529, -529, -409, -529}}, +/* UG.G.. @ */ +{{ -100, -709, -859, -969, -859},{ -100, -709, -859, -969, -859},{ -100, -709, -859, -969, -859},{ -100, -709, -859, -969, -859},{ -100, -709, -859, -969, -859}}, +/* UG.U.. @ */ +{{ -100, -599, -489, -599, -409},{ -100, -599, -489, -599, -409},{ -100, -599, -489, -599, -409},{ -100, -599, -489, -599, -409},{ -100, -599, -489, -599, -409}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* AU.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..CG */ +{{ DEF, -429, -599, -599, -599},{-1079,-1458,-1628,-1628,-1628},{ -569, -948,-1118,-1118,-1118},{ -989,-1368,-1538,-1538,-1538},{ -859,-1238,-1408,-1408,-1408}}, +/* AU.C..CG */ +{{ DEF, -259, -239, -239, -239},{ -999,-1208,-1188,-1188,-1188},{ -499, -708, -688, -688, -688},{ -989,-1198,-1178,-1178,-1178},{ -789, -998, -978, -978, -978}}, +/* AU.G..CG */ +{{ DEF, -339, -689, -689, -689},{-1079,-1368,-1718,-1718,-1718},{ -569, -858,-1208,-1208,-1208},{ -989,-1278,-1628,-1628,-1628},{ -859,-1148,-1498,-1498,-1498}}, +/* AU.U..CG */ +{{ DEF, -329, -329, -329, -329},{-1079,-1358,-1358,-1358,-1358},{ -719, -998, -998, -998, -998},{ -989,-1268,-1268,-1268,-1268},{ -909,-1188,-1188,-1188,-1188}} +}, +{ +/* AU.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..GC */ +{{ DEF, -429, -599, -599, -599},{ -569, -948,-1118,-1118,-1118},{ -769,-1148,-1318,-1318,-1318},{ -759,-1138,-1308,-1308,-1308},{ -549, -928,-1098,-1098,-1098}}, +/* AU.C..GC */ +{{ DEF, -259, -239, -239, -239},{ -929,-1138,-1118,-1118,-1118},{ -359, -568, -548, -548, -548},{ -789, -998, -978, -978, -978},{ -549, -758, -738, -738, -738}}, +/* AU.G..GC */ +{{ DEF, -339, -689, -689, -689},{ -609, -898,-1248,-1248,-1248},{ -359, -648, -998, -998, -998},{ -669, -958,-1308,-1308,-1308},{ -549, -838,-1188,-1188,-1188}}, +/* AU.U..GC */ +{{ DEF, -329, -329, -329, -329},{ -929,-1208,-1208,-1208,-1208},{ -439, -718, -718, -718, -718},{ -789,-1068,-1068,-1068,-1068},{ -619, -898, -898, -898, -898}} +}, +{ +/* AU.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..GU */ +{{ DEF, -429, -599, -599, -599},{ -479, -858,-1028,-1028,-1028},{ -309, -688, -858, -858, -858},{ -389, -768, -938, -938, -938},{ -379, -758, -928, -928, -928}}, +/* AU.C..GU */ +{{ DEF, -259, -239, -239, -239},{ -649, -858, -838, -838, -838},{ -289, -498, -478, -478, -478},{ -739, -948, -928, -928, -928},{ -379, -588, -568, -568, -568}}, +/* AU.G..GU */ +{{ DEF, -339, -689, -689, -689},{ -649, -938,-1288,-1288,-1288},{ -289, -578, -928, -928, -928},{ -739,-1028,-1378,-1378,-1378},{ -379, -668,-1018,-1018,-1018}}, +/* AU.U..GU */ +{{ DEF, -329, -329, -329, -329},{ -649, -928, -928, -928, -928},{ -289, -568, -568, -568, -568},{ -739,-1018,-1018,-1018,-1018},{ -379, -658, -658, -658, -658}} +}, +{ +/* AU.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..UG */ +{{ DEF, -429, -599, -599, -599},{ -769,-1148,-1318,-1318,-1318},{ -529, -908,-1078,-1078,-1078},{ -709,-1088,-1258,-1258,-1258},{ -599, -978,-1148,-1148,-1148}}, +/* AU.C..UG */ +{{ DEF, -259, -239, -239, -239},{ -839,-1048,-1028,-1028,-1028},{ -529, -738, -718, -718, -718},{ -859,-1068,-1048,-1048,-1048},{ -489, -698, -678, -678, -678}}, +/* AU.G..UG */ +{{ DEF, -339, -689, -689, -689},{-1009,-1298,-1648,-1648,-1648},{ -409, -698,-1048,-1048,-1048},{ -969,-1258,-1608,-1608,-1608},{ -599, -888,-1238,-1238,-1238}}, +/* AU.U..UG */ +{{ DEF, -329, -329, -329, -329},{ -859,-1138,-1138,-1138,-1138},{ -529, -808, -808, -808, -808},{ -859,-1138,-1138,-1138,-1138},{ -409, -688, -688, -688, -688}} +}, +{ +/* AU.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..AU */ +{{ DEF, -429, -599, -599, -599},{ -479, -858,-1028,-1028,-1028},{ -309, -688, -858, -858, -858},{ -389, -768, -938, -938, -938},{ -379, -758, -928, -928, -928}}, +/* AU.C..AU */ +{{ DEF, -259, -239, -239, -239},{ -649, -858, -838, -838, -838},{ -289, -498, -478, -478, -478},{ -739, -948, -928, -928, -928},{ -379, -588, -568, -568, -568}}, +/* AU.G..AU */ +{{ DEF, -339, -689, -689, -689},{ -649, -938,-1288,-1288,-1288},{ -289, -578, -928, -928, -928},{ -739,-1028,-1378,-1378,-1378},{ -379, -668,-1018,-1018,-1018}}, +/* AU.U..AU */ +{{ DEF, -329, -329, -329, -329},{ -649, -928, -928, -928, -928},{ -289, -568, -568, -568, -568},{ -739,-1018,-1018,-1018,-1018},{ -379, -658, -658, -658, -658}} +}, +{ +/* AU.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A..UA */ +{{ DEF, -429, -599, -599, -599},{ -449, -828, -998, -998, -998},{ -479, -858,-1028,-1028,-1028},{ -429, -808, -978, -978, -978},{ -329, -708, -878, -878, -878}}, +/* AU.C..UA */ +{{ DEF, -259, -239, -239, -239},{ -679, -888, -868, -868, -868},{ -559, -768, -748, -748, -748},{ -729, -938, -918, -918, -918},{ -189, -398, -378, -378, -378}}, +/* AU.G..UA */ +{{ DEF, -339, -689, -689, -689},{ -939,-1228,-1578,-1578,-1578},{ -249, -538, -888, -888, -888},{ -939,-1228,-1578,-1578,-1578},{ -329, -618, -968, -968, -968}}, +/* AU.U..UA */ +{{ DEF, -329, -329, -329, -329},{ -639, -918, -918, -918, -918},{ -229, -508, -508, -508, -508},{ -729,-1008,-1008,-1008,-1008},{ -190, -469, -469, -469, -469}} +}, +{ +/* AU.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.A.. @ */ +{{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649},{ -100, -479, -649, -649, -649}}, +/* AU.C.. @ */ +{{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289},{ -100, -309, -289, -289, -289}}, +/* AU.G.. @ */ +{{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739},{ -100, -389, -739, -739, -739}}, +/* AU.U.. @ */ +{{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379},{ -100, -379, -379, -379, -379}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* UA.@..CG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..CG */ +{{ DEF, -399, -629, -889, -589},{-1079,-1428,-1658,-1918,-1618},{ -569, -918,-1148,-1408,-1108},{ -989,-1338,-1568,-1828,-1528},{ -859,-1208,-1438,-1698,-1398}}, +/* UA.C..CG */ +{{ DEF, -429, -509, -199, -179},{ -999,-1378,-1458,-1148,-1128},{ -499, -878, -958, -648, -628},{ -989,-1368,-1448,-1138,-1118},{ -789,-1168,-1248, -938, -918}}, +/* UA.G..CG */ +{{ DEF, -379, -679, -889, -679},{-1079,-1408,-1708,-1918,-1708},{ -569, -898,-1198,-1408,-1198},{ -989,-1318,-1618,-1828,-1618},{ -859,-1188,-1488,-1698,-1488}}, +/* UA.U..CG */ +{{ DEF, -279, -139, -279, -140},{-1079,-1308,-1168,-1308,-1169},{ -719, -948, -808, -948, -809},{ -989,-1218,-1078,-1218,-1079},{ -909,-1138, -998,-1138, -999}} +}, +{ +/* UA.@..GC */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..GC */ +{{ DEF, -399, -629, -889, -589},{ -569, -918,-1148,-1408,-1108},{ -769,-1118,-1348,-1608,-1308},{ -759,-1108,-1338,-1598,-1298},{ -549, -898,-1128,-1388,-1088}}, +/* UA.C..GC */ +{{ DEF, -429, -509, -199, -179},{ -929,-1308,-1388,-1078,-1058},{ -359, -738, -818, -508, -488},{ -789,-1168,-1248, -938, -918},{ -549, -928,-1008, -698, -678}}, +/* UA.G..GC */ +{{ DEF, -379, -679, -889, -679},{ -609, -938,-1238,-1448,-1238},{ -359, -688, -988,-1198, -988},{ -669, -998,-1298,-1508,-1298},{ -549, -878,-1178,-1388,-1178}}, +/* UA.U..GC */ +{{ DEF, -279, -139, -279, -140},{ -929,-1158,-1018,-1158,-1019},{ -439, -668, -528, -668, -529},{ -789,-1018, -878,-1018, -879},{ -619, -848, -708, -848, -709}} +}, +{ +/* UA.@..GU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..GU */ +{{ DEF, -399, -629, -889, -589},{ -479, -828,-1058,-1318,-1018},{ -309, -658, -888,-1148, -848},{ -389, -738, -968,-1228, -928},{ -379, -728, -958,-1218, -918}}, +/* UA.C..GU */ +{{ DEF, -429, -509, -199, -179},{ -649,-1028,-1108, -798, -778},{ -289, -668, -748, -438, -418},{ -739,-1118,-1198, -888, -868},{ -379, -758, -838, -528, -508}}, +/* UA.G..GU */ +{{ DEF, -379, -679, -889, -679},{ -649, -978,-1278,-1488,-1278},{ -289, -618, -918,-1128, -918},{ -739,-1068,-1368,-1578,-1368},{ -379, -708,-1008,-1218,-1008}}, +/* UA.U..GU */ +{{ DEF, -279, -139, -279, -140},{ -649, -878, -738, -878, -739},{ -289, -518, -378, -518, -379},{ -739, -968, -828, -968, -829},{ -379, -608, -468, -608, -469}} +}, +{ +/* UA.@..UG */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..UG */ +{{ DEF, -399, -629, -889, -589},{ -769,-1118,-1348,-1608,-1308},{ -529, -878,-1108,-1368,-1068},{ -709,-1058,-1288,-1548,-1248},{ -599, -948,-1178,-1438,-1138}}, +/* UA.C..UG */ +{{ DEF, -429, -509, -199, -179},{ -839,-1218,-1298, -988, -968},{ -529, -908, -988, -678, -658},{ -859,-1238,-1318,-1008, -988},{ -489, -868, -948, -638, -618}}, +/* UA.G..UG */ +{{ DEF, -379, -679, -889, -679},{-1009,-1338,-1638,-1848,-1638},{ -409, -738,-1038,-1248,-1038},{ -969,-1298,-1598,-1808,-1598},{ -599, -928,-1228,-1438,-1228}}, +/* UA.U..UG */ +{{ DEF, -279, -139, -279, -140},{ -859,-1088, -948,-1088, -949},{ -529, -758, -618, -758, -619},{ -859,-1088, -948,-1088, -949},{ -409, -638, -498, -638, -499}} +}, +{ +/* UA.@..AU */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..AU */ +{{ DEF, -399, -629, -889, -589},{ -479, -828,-1058,-1318,-1018},{ -309, -658, -888,-1148, -848},{ -389, -738, -968,-1228, -928},{ -379, -728, -958,-1218, -918}}, +/* UA.C..AU */ +{{ DEF, -429, -509, -199, -179},{ -649,-1028,-1108, -798, -778},{ -289, -668, -748, -438, -418},{ -739,-1118,-1198, -888, -868},{ -379, -758, -838, -528, -508}}, +/* UA.G..AU */ +{{ DEF, -379, -679, -889, -679},{ -649, -978,-1278,-1488,-1278},{ -289, -618, -918,-1128, -918},{ -739,-1068,-1368,-1578,-1368},{ -379, -708,-1008,-1218,-1008}}, +/* UA.U..AU */ +{{ DEF, -279, -139, -279, -140},{ -649, -878, -738, -878, -739},{ -289, -518, -378, -518, -379},{ -739, -968, -828, -968, -829},{ -379, -608, -468, -608, -469}} +}, +{ +/* UA.@..UA */ +{{ 0, 0, 0, 0, 0},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A..UA */ +{{ DEF, -399, -629, -889, -589},{ -449, -798,-1028,-1288, -988},{ -479, -828,-1058,-1318,-1018},{ -429, -778,-1008,-1268, -968},{ -329, -678, -908,-1168, -868}}, +/* UA.C..UA */ +{{ DEF, -429, -509, -199, -179},{ -679,-1058,-1138, -828, -808},{ -559, -938,-1018, -708, -688},{ -729,-1108,-1188, -878, -858},{ -189, -568, -648, -338, -318}}, +/* UA.G..UA */ +{{ DEF, -379, -679, -889, -679},{ -939,-1268,-1568,-1778,-1568},{ -249, -578, -878,-1088, -878},{ -939,-1268,-1568,-1778,-1568},{ -329, -658, -958,-1168, -958}}, +/* UA.U..UA */ +{{ DEF, -279, -139, -279, -140},{ -639, -868, -728, -868, -729},{ -229, -458, -318, -458, -319},{ -729, -958, -818, -958, -819},{ -190, -419, -279, -419, -280}} +}, +{ +/* UA.@.. @ */ +{{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF},{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.A.. @ */ +{{ -100, -449, -679, -939, -639},{ -100, -449, -679, -939, -639},{ -100, -449, -679, -939, -639},{ -100, -449, -679, -939, -639},{ -100, -449, -679, -939, -639}}, +/* UA.C.. @ */ +{{ -100, -479, -559, -249, -229},{ -100, -479, -559, -249, -229},{ -100, -479, -559, -249, -229},{ -100, -479, -559, -249, -229},{ -100, -479, -559, -249, -229}}, +/* UA.G.. @ */ +{{ -100, -429, -729, -939, -729},{ -100, -429, -729, -939, -729},{ -100, -429, -729, -939, -729},{ -100, -429, -729, -939, -729},{ -100, -429, -729, -939, -729}}, +/* UA.U.. @ */ +{{ -100, -329, -189, -329, -190},{ -100, -329, -189, -329, -190},{ -100, -329, -189, -329, -190},{ -100, -329, -189, -329, -190},{ -100, -329, -189, -329, -190}} +} +}, +{ /* noPair */ {{{0}}}, +{ +/* @.@..CG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..CG */ +{{ DEF, DEF, DEF, DEF, DEF},{-1079,-1079,-1079,-1079,-1079},{ -569, -569, -569, -569, -569},{ -989, -989, -989, -989, -989},{ -859, -859, -859, -859, -859}}, +/* @.C..CG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -999, -999, -999, -999, -999},{ -499, -499, -499, -499, -499},{ -989, -989, -989, -989, -989},{ -789, -789, -789, -789, -789}}, +/* @.G..CG */ +{{ DEF, DEF, DEF, DEF, DEF},{-1079,-1079,-1079,-1079,-1079},{ -569, -569, -569, -569, -569},{ -989, -989, -989, -989, -989},{ -859, -859, -859, -859, -859}}, +/* @.U..CG */ +{{ DEF, DEF, DEF, DEF, DEF},{-1079,-1079,-1079,-1079,-1079},{ -719, -719, -719, -719, -719},{ -989, -989, -989, -989, -989},{ -909, -909, -909, -909, -909}} +}, +{ +/* @.@..GC */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..GC */ +{{ DEF, DEF, DEF, DEF, DEF},{ -569, -569, -569, -569, -569},{ -769, -769, -769, -769, -769},{ -759, -759, -759, -759, -759},{ -549, -549, -549, -549, -549}}, +/* @.C..GC */ +{{ DEF, DEF, DEF, DEF, DEF},{ -929, -929, -929, -929, -929},{ -359, -359, -359, -359, -359},{ -789, -789, -789, -789, -789},{ -549, -549, -549, -549, -549}}, +/* @.G..GC */ +{{ DEF, DEF, DEF, DEF, DEF},{ -609, -609, -609, -609, -609},{ -359, -359, -359, -359, -359},{ -669, -669, -669, -669, -669},{ -549, -549, -549, -549, -549}}, +/* @.U..GC */ +{{ DEF, DEF, DEF, DEF, DEF},{ -929, -929, -929, -929, -929},{ -439, -439, -439, -439, -439},{ -789, -789, -789, -789, -789},{ -619, -619, -619, -619, -619}} +}, +{ +/* @.@..GU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..GU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -479, -479, -479, -479, -479},{ -309, -309, -309, -309, -309},{ -389, -389, -389, -389, -389},{ -379, -379, -379, -379, -379}}, +/* @.C..GU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}}, +/* @.G..GU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}}, +/* @.U..GU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}} +}, +{ +/* @.@..UG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..UG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -769, -769, -769, -769, -769},{ -529, -529, -529, -529, -529},{ -709, -709, -709, -709, -709},{ -599, -599, -599, -599, -599}}, +/* @.C..UG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -839, -839, -839, -839, -839},{ -529, -529, -529, -529, -529},{ -859, -859, -859, -859, -859},{ -489, -489, -489, -489, -489}}, +/* @.G..UG */ +{{ DEF, DEF, DEF, DEF, DEF},{-1009,-1009,-1009,-1009,-1009},{ -409, -409, -409, -409, -409},{ -969, -969, -969, -969, -969},{ -599, -599, -599, -599, -599}}, +/* @.U..UG */ +{{ DEF, DEF, DEF, DEF, DEF},{ -859, -859, -859, -859, -859},{ -529, -529, -529, -529, -529},{ -859, -859, -859, -859, -859},{ -409, -409, -409, -409, -409}} +}, +{ +/* @.@..AU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..AU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -479, -479, -479, -479, -479},{ -309, -309, -309, -309, -309},{ -389, -389, -389, -389, -389},{ -379, -379, -379, -379, -379}}, +/* @.C..AU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}}, +/* @.G..AU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}}, +/* @.U..AU */ +{{ DEF, DEF, DEF, DEF, DEF},{ -649, -649, -649, -649, -649},{ -289, -289, -289, -289, -289},{ -739, -739, -739, -739, -739},{ -379, -379, -379, -379, -379}} +}, +{ +/* @.@..UA */ +{{ DEF, DEF, DEF, DEF, DEF},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A..UA */ +{{ DEF, DEF, DEF, DEF, DEF},{ -449, -449, -449, -449, -449},{ -479, -479, -479, -479, -479},{ -429, -429, -429, -429, -429},{ -329, -329, -329, -329, -329}}, +/* @.C..UA */ +{{ DEF, DEF, DEF, DEF, DEF},{ -679, -679, -679, -679, -679},{ -559, -559, -559, -559, -559},{ -729, -729, -729, -729, -729},{ -189, -189, -189, -189, -189}}, +/* @.G..UA */ +{{ DEF, DEF, DEF, DEF, DEF},{ -939, -939, -939, -939, -939},{ -249, -249, -249, -249, -249},{ -939, -939, -939, -939, -939},{ -329, -329, -329, -329, -329}}, +/* @.U..UA */ +{{ DEF, DEF, DEF, DEF, DEF},{ -639, -639, -639, -639, -639},{ -229, -229, -229, -229, -229},{ -729, -729, -729, -729, -729},{ -190, -190, -190, -190, -190}} +}, +{ +/* @.@.. @ */ +{{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.A.. @ */ +{{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.C.. @ */ +{{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.G.. @ */ +{{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}}, +/* @.U.. @ */ +{{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100},{ -100, -100, -100, -100, -100}} +} +} +}; + +PUBLIC int int22_37[NBPAIRS+1][NBPAIRS+1][5][5][5][5] = { +/* noPair */ {{{{{0}}}}}, +{ /* noPair */ {{{{0}}}}, +/* CG....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 160, 30, 200},{ 340, 120, 150, 20, 200},{ 340, 30, 60, -70, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 200, 60, 200},{ 340, 210, 180, 150, 200},{ 340, 200, 200, 200, 200},{ 340, 190, 170, 130, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 60, -70, 200},{ 340, 200, 200, 200, 200},{ 340, 100, 140, 0, 200},{ 340, -40, -110, -60, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 190, 170, 130, 200},{ 340, 110, 40, 90, 200},{ 340, 140, 80, 130, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 120, 210, 200, 190},{ 340, 110, 140, 200, 120},{ 340, 20, 150, 200, 130},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 180, 200, 170},{ 340, 140, 170, 200, 150},{ 340, 200, 200, 200, 200},{ 340, 120, 150, 200, 140}}, +{{ 340, 340, 340, 340, 340},{ 340, 20, 150, 200, 130},{ 340, 200, 200, 200, 200},{ 340, 90, 180, 200, 170},{ 340, -150, -20, 200, -40}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 120, 150, 200, 140},{ 340, 0, 130, 200, 110},{ 340, 30, 60, 200, 50}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 200, 100, 110},{ 340, 20, 200, 90, 0},{ 340, -70, 200, 0, 90},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 200, 140, 40},{ 340, 150, 200, 180, 130},{ 340, 200, 200, 200, 200},{ 340, 130, 200, 170, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, -70, 200, 0, 90},{ 340, 200, 200, 200, 200},{ 340, 0, 200, 80, 90},{ 340, -60, 200, -70, -260}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 130, 200, 170, 110},{ 340, 90, 200, 90, -110},{ 340, 130, 200, 120, 110}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 190, -40, 140},{ 340, 200, 120, -150, 30},{ 340, 200, 130, -60, 130},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, -110, 80},{ 340, 200, 150, -20, 60},{ 340, 200, 200, 200, 200},{ 340, 200, 140, -40, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 130, -60, 130},{ 340, 200, 200, 200, 200},{ 340, 200, 170, -70, 120},{ 340, 200, -40, -420, -50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 140, -40, 50},{ 340, 200, 110, -260, 110},{ 340, 200, 50, -50, -40}} +} +}, +/* CG....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 60, 0, 200},{ 340, 110, 150, -70, 200},{ 340, -30, 10, -160, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 110, -100, 200},{ 340, 170, 150, -60, 200},{ 340, 200, 200, 200, 200},{ 340, 70, 50, 20, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 40, 50, -70, 200},{ 340, 200, 200, 200, 200},{ 340, 100, 140, 0, 200},{ 340, 10, -70, -80, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 180, 150, 120, 200},{ 340, -50, -60, -60, 200},{ 340, 150, 0, 90, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 220, 200, 200},{ 340, 100, 130, 200, 120},{ 340, -70, 70, 200, 40},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 190, 200, 110},{ 340, 100, 130, 200, 120},{ 340, 200, 200, 200, 200},{ 340, 0, 30, 200, 170}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 70, 200, 100},{ 340, 200, 200, 200, 200},{ 340, 90, 180, 200, 170},{ 340, -190, -30, 200, -70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 110, 140, 200, 120},{ 340, -150, -20, 200, -30},{ 340, -20, -10, 200, 20}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, -20, 200, 110, 90},{ 340, -40, 200, 90, 0},{ 340, -170, 200, -90, 30},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 80, -10},{ 340, 110, 200, 150, 100},{ 340, 200, 200, 200, 200},{ 340, 20, 200, 50, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, -50, 200, -20, 60},{ 340, 200, 200, 200, 200},{ 340, 0, 200, 80, 90},{ 340, -90, 200, -100, -300}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 120, 200, 150, 100},{ 340, -130, 200, -60, -240},{ 340, 90, 200, 110, 60}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, -10, 140},{ 340, 200, 120, -160, 30},{ 340, 200, 40, -160, 50},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 110, -160, 30},{ 340, 200, 120, -60, 30},{ 340, 200, 200, 200, 200},{ 340, 200, 20, -160, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 50, -60, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 170, -70, 120},{ 340, 200, -70, -440, -100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 120, -50, 30},{ 340, 200, -10, -410, 10},{ 340, 200, 40, -100, 60}} +} +}, +/* CG....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 180, 210, 80, 200},{ 340, 80, 110, -20, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 220, 90, 200},{ 340, 230, 210, 170, 200},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 110, -20, 200},{ 340, 200, 200, 200, 200},{ 340, 130, 170, 30, 200},{ 340, 60, 0, 40, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200},{ 340, 160, 90, 140, 200},{ 340, 190, 130, 180, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 280, 200, 270},{ 340, 170, 200, 200, 180},{ 340, 70, 200, 200, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 210, 200, 190},{ 340, 160, 190, 200, 180},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 200, 180},{ 340, 200, 200, 200, 200},{ 340, 120, 210, 200, 200},{ 340, -50, 80, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180},{ 340, 50, 180, 200, 160},{ 340, 80, 110, 200, 100}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 180},{ 340, 80, 200, 150, 60},{ 340, -20, 200, 50, 140},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 200, 160, 70},{ 340, 170, 200, 210, 150},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150}}, +{{ 340, 340, 340, 340, 340},{ 340, -20, 200, 50, 140},{ 340, 200, 200, 200, 200},{ 340, 30, 200, 110, 110},{ 340, 40, 200, 40, -160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150},{ 340, 140, 200, 130, -60},{ 340, 180, 200, 170, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 220},{ 340, 200, 180, -90, 90},{ 340, 200, 180, -10, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 190, -80, 100},{ 340, 200, 180, 0, 90},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 180, -10, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 200, -40, 150},{ 340, 200, 70, -310, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90},{ 340, 200, 160, -210, 160},{ 340, 200, 100, 0, 10}} +} +}, +/* CG....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 160, 190, 60, 200},{ 340, 100, 130, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 260, 240, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 260, 240, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 130, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 140, 170, 40, 200},{ 340, 20, -40, 0, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200},{ 340, 150, 80, 130, 200},{ 340, 220, 150, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 280, 200, 270},{ 340, 150, 180, 200, 160},{ 340, 90, 220, 200, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 220, 200, 210},{ 340, 190, 220, 200, 210},{ 340, 200, 200, 200, 200},{ 340, 190, 220, 200, 210}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 220, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 130, 220, 200, 200},{ 340, -90, 40, 200, 30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180},{ 340, 40, 170, 200, 150},{ 340, 110, 140, 200, 120}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 180},{ 340, 60, 200, 130, 40},{ 340, 0, 200, 70, 160},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 80},{ 340, 200, 200, 240, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 240, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 40, 200, 110, 120},{ 340, 0, 200, 0, -200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150},{ 340, 130, 200, 120, -70},{ 340, 200, 200, 190, 180}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 220},{ 340, 200, 160, -110, 70},{ 340, 200, 200, 10, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 210, -70, 120},{ 340, 200, 210, 30, 120},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 10, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 200, -30, 150},{ 340, 200, 30, -350, 20}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90},{ 340, 200, 150, -220, 150},{ 340, 200, 120, 30, 30}} +} +}, +/* CG....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 180, 210, 80, 200},{ 340, 80, 110, -20, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 220, 90, 200},{ 340, 230, 210, 170, 200},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 110, -20, 200},{ 340, 200, 200, 200, 200},{ 340, 130, 170, 30, 200},{ 340, 60, 0, 40, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200},{ 340, 160, 90, 140, 200},{ 340, 190, 130, 180, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 280, 200, 270},{ 340, 170, 200, 200, 180},{ 340, 70, 200, 200, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 210, 200, 190},{ 340, 160, 190, 200, 180},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 200, 180},{ 340, 200, 200, 200, 200},{ 340, 120, 210, 200, 200},{ 340, -50, 80, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180},{ 340, 50, 180, 200, 160},{ 340, 80, 110, 200, 100}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 180},{ 340, 80, 200, 150, 60},{ 340, -20, 200, 50, 140},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 200, 160, 70},{ 340, 170, 200, 210, 150},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150}}, +{{ 340, 340, 340, 340, 340},{ 340, -20, 200, 50, 140},{ 340, 200, 200, 200, 200},{ 340, 30, 200, 110, 110},{ 340, 40, 200, 40, -160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150},{ 340, 140, 200, 130, -60},{ 340, 180, 200, 170, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 220},{ 340, 200, 180, -90, 90},{ 340, 200, 180, -10, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 190, -80, 100},{ 340, 200, 180, 0, 90},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 180, -10, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 200, -40, 150},{ 340, 200, 70, -310, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90},{ 340, 200, 160, -210, 160},{ 340, 200, 100, 0, 10}} +} +}, +/* CG....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 160, 190, 60, 200},{ 340, 100, 130, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 100, 200},{ 340, 260, 240, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 260, 240, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 130, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 140, 170, 40, 200},{ 340, 20, -40, 0, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 230, 210, 170, 200},{ 340, 150, 80, 130, 200},{ 340, 220, 150, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 280, 200, 270},{ 340, 150, 180, 200, 160},{ 340, 90, 220, 200, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 220, 200, 210},{ 340, 190, 220, 200, 210},{ 340, 200, 200, 200, 200},{ 340, 190, 220, 200, 210}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 220, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 130, 220, 200, 200},{ 340, -90, 40, 200, 30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 190, 200, 180},{ 340, 40, 170, 200, 150},{ 340, 110, 140, 200, 120}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 180},{ 340, 60, 200, 130, 40},{ 340, 0, 200, 70, 160},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 180, 80},{ 340, 200, 200, 240, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 240, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 40, 200, 110, 120},{ 340, 0, 200, 0, -200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 210, 150},{ 340, 130, 200, 120, -70},{ 340, 200, 200, 190, 180}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 220},{ 340, 200, 160, -110, 70},{ 340, 200, 200, 10, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 210, -70, 120},{ 340, 200, 210, 30, 120},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 10, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 200, -30, 150},{ 340, 200, 30, -350, 20}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 0, 90},{ 340, 200, 150, -220, 150},{ 340, 200, 120, 30, 30}} +} +}, +/* CG....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +}, +{ /* noPair */ {{{{0}}}}, +/* GC....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 110, 40, 200},{ 340, 130, 100, 70, 200},{ 340, -20, 70, -50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 110, 50, 200},{ 340, 220, 190, 70, 200},{ 340, 200, 200, 200, 200},{ 340, 200, 110, 50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, -100, -70, 200},{ 340, 200, 200, 200, 200},{ 340, 110, 80, -20, 200},{ 340, -10, -160, -60, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 110, 100, 200},{ 340, 90, -10, 60, 200},{ 340, 140, 30, 140, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 170, 200, 180},{ 340, 100, 100, 200, 110},{ 340, -40, 110, 200, 120},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 150, 200, 150},{ 340, 130, 130, 200, 140},{ 340, 200, 200, 200, 200},{ 340, 120, 120, 200, 120}}, +{{ 340, 340, 340, 340, 340},{ 340, -70, -60, 200, 120},{ 340, 200, 200, 200, 200},{ 340, 90, 150, 200, 150},{ 340, -160, -60, 200, -50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 120, 120, 200, 120},{ 340, 0, 100, 200, 100},{ 340, 30, 30, 200, 30}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, -30, 200, 100, -50},{ 340, -70, 200, 90, -150},{ 340, -170, 200, 0, -130},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 140, -60},{ 340, 70, 200, 180, -20},{ 340, 200, 200, 200, 200},{ 340, 40, 200, 170, -10}}, +{{ 340, 340, 340, 340, 340},{ 340, -160, 200, 0, -60},{ 340, 200, 200, 200, 200},{ 340, -90, 200, 80, -60},{ 340, -160, 200, -70, -410}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 40, 200, 170, -30},{ 340, 30, 200, 90, -240},{ 340, 50, 200, 120, 10}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 70, 10, 150},{ 340, 200, 0, -190, -20},{ 340, 200, 20, -90, 90},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 50, -70, 0},{ 340, 200, 30, -30, -10},{ 340, 200, 200, 200, 200},{ 340, 200, 20, -70, 40}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 20, -80, 90},{ 340, 200, 200, 200, 200},{ 340, 200, 50, -100, 110},{ 340, 200, -160, -440, -100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 170, -70, 20},{ 340, 200, 0, -300, 60},{ 340, 200, 10, -100, 60}} +} +}, +/* GC....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 120, 10, 200},{ 340, 120, 90, -10, 200},{ 340, -50, -80, -190, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 120, 90, -20, 200},{ 340, 180, 90, 90, 200},{ 340, 200, 200, 200, 200},{ 340, 80, 0, -10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, -20, -130, 200},{ 340, 200, 200, 200, 200},{ 340, 110, 80, -20, 200},{ 340, -70, -200, -130, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 190, 100, 90, 200},{ 340, -30, -160, -90, 200},{ 340, 150, 20, 90, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 120, 180, 200, 190},{ 340, 100, 100, 200, 100},{ 340, -80, 20, 200, 30},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 90, 200, 100},{ 340, 100, 100, 200, 100},{ 340, 200, 200, 200, 200},{ 340, 0, 0, 200, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, -10, 90, 200, 90},{ 340, 200, 200, 200, 200},{ 340, 90, 150, 200, 150},{ 340, -190, -90, 200, -90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 100, 100, 200, 110},{ 340, -150, -50, 200, -50},{ 340, 20, 20, 200, 30}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, -50, 200, 110, -30},{ 340, -80, 200, 90, -150},{ 340, -260, 200, -90, -150},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, -80, 200, 80, -160},{ 340, 20, 200, 150, -50},{ 340, 200, 200, 200, 200},{ 340, -80, 200, 50, -150}}, +{{ 340, 340, 340, 340, 340},{ 340, -190, 200, -20, -90},{ 340, 200, 200, 200, 200},{ 340, -90, 200, 80, -60},{ 340, -190, 200, -100, -450}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 30, 200, 150, -50},{ 340, -150, 200, -60, -410},{ 340, 30, 200, 110, -50}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 80, -70, 150},{ 340, 200, 0, -190, 20},{ 340, 200, -80, -190, 30},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 0, -200, 20},{ 340, 200, 0, -90, 20},{ 340, 200, 200, 200, 200},{ 340, 200, -100, -190, -70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, -10, -130, 90},{ 340, 200, 200, 200, 200},{ 340, 200, 50, -100, 110},{ 340, 200, -190, -490, -90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 0, -90, 30},{ 340, 200, -150, -450, -50},{ 340, 200, -70, -90, -50}} +} +}, +/* GC....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 190, 160, 50, 200},{ 340, 90, 60, -50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, 60, 200},{ 340, 240, 150, 140, 200},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 60, -50, 200},{ 340, 200, 200, 200, 200},{ 340, 140, 110, 0, 200},{ 340, 70, -60, 10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200},{ 340, 170, 40, 110, 200},{ 340, 200, 70, 150, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 250, 200, 250},{ 340, 160, 160, 200, 170},{ 340, 60, 160, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 200, 180},{ 340, 160, 160, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 160, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 120, 180, 200, 180},{ 340, -50, 50, 200, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160},{ 340, 40, 140, 200, 150},{ 340, 80, 80, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, 40},{ 340, -10, 200, 150, -90},{ 340, -110, 200, 50, -10},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 160, -80},{ 340, 80, 200, 210, 10},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, -110, 200, 50, -10},{ 340, 200, 200, 200, 200},{ 340, -60, 200, 110, -30},{ 340, -50, 200, 40, -310}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10},{ 340, 50, 200, 130, -210},{ 340, 80, 200, 170, 10}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, 0, 210},{ 340, 200, 60, -130, 90},{ 340, 200, 70, -50, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 70, -120, 100},{ 340, 200, 60, -30, 80},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 70, -50, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 80, -70, 140},{ 340, 200, -50, -350, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80},{ 340, 200, 50, -250, 150},{ 340, 200, -20, -30, 0}} +} +}, +/* GC....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 170, 140, 30, 200},{ 340, 110, 80, -30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 270, 180, 170, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 180, 170, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 80, -30, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 120, 10, 200},{ 340, 30, -100, -30, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200},{ 340, 160, 30, 100, 200},{ 340, 230, 100, 170, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 250, 200, 250},{ 340, 140, 140, 200, 150},{ 340, 80, 180, 200, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 190, 200, 190},{ 340, 190, 190, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 190, 190, 200, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 180, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 120, 180, 200, 190},{ 340, -90, 10, 200, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160},{ 340, 30, 130, 200, 140},{ 340, 100, 100, 200, 110}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, 40},{ 340, -30, 200, 130, -110},{ 340, -90, 200, 70, 10},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, -60},{ 340, 110, 200, 240, 40},{ 340, 200, 200, 200, 200},{ 340, 110, 200, 240, 40}}, +{{ 340, 340, 340, 340, 340},{ 340, -90, 200, 70, 10},{ 340, 200, 200, 200, 200},{ 340, -50, 200, 110, -30},{ 340, -90, 200, 0, -350}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10},{ 340, 40, 200, 120, -220},{ 340, 110, 200, 190, 30}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, 0, 210},{ 340, 200, 40, -150, 70},{ 340, 200, 90, -30, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 90, -100, 110},{ 340, 200, 90, 0, 110},{ 340, 200, 200, 200, 200},{ 340, 200, 90, 0, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 90, -30, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 80, -70, 150},{ 340, 200, -90, -390, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80},{ 340, 200, 40, -260, 140},{ 340, 200, 0, -10, 30}} +} +}, +/* GC....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 190, 160, 50, 200},{ 340, 90, 60, -50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, 60, 200},{ 340, 240, 150, 140, 200},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 60, -50, 200},{ 340, 200, 200, 200, 200},{ 340, 140, 110, 0, 200},{ 340, 70, -60, 10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200},{ 340, 170, 40, 110, 200},{ 340, 200, 70, 150, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 250, 200, 250},{ 340, 160, 160, 200, 170},{ 340, 60, 160, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 200, 180},{ 340, 160, 160, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 160, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 120, 180, 200, 180},{ 340, -50, 50, 200, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160},{ 340, 40, 140, 200, 150},{ 340, 80, 80, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, 40},{ 340, -10, 200, 150, -90},{ 340, -110, 200, 50, -10},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 160, -80},{ 340, 80, 200, 210, 10},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, -110, 200, 50, -10},{ 340, 200, 200, 200, 200},{ 340, -60, 200, 110, -30},{ 340, -50, 200, 40, -310}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10},{ 340, 50, 200, 130, -210},{ 340, 80, 200, 170, 10}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, 0, 210},{ 340, 200, 60, -130, 90},{ 340, 200, 70, -50, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 70, -120, 100},{ 340, 200, 60, -30, 80},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 70, -50, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 80, -70, 140},{ 340, 200, -50, -350, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80},{ 340, 200, 50, -250, 150},{ 340, 200, -20, -30, 0}} +} +}, +/* GC....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 170, 140, 30, 200},{ 340, 110, 80, -30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 180, 70, 200},{ 340, 270, 180, 170, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 180, 170, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 80, -30, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 120, 10, 200},{ 340, 30, -100, -30, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 150, 140, 200},{ 340, 160, 30, 100, 200},{ 340, 230, 100, 170, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 250, 200, 250},{ 340, 140, 140, 200, 150},{ 340, 80, 180, 200, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 190, 200, 190},{ 340, 190, 190, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 190, 190, 200, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 180, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 120, 180, 200, 190},{ 340, -90, 10, 200, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 160, 200, 160},{ 340, 30, 130, 200, 140},{ 340, 100, 100, 200, 110}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, 40},{ 340, -30, 200, 130, -110},{ 340, -90, 200, 70, 10},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 10, 200, 180, -60},{ 340, 110, 200, 240, 40},{ 340, 200, 200, 200, 200},{ 340, 110, 200, 240, 40}}, +{{ 340, 340, 340, 340, 340},{ 340, -90, 200, 70, 10},{ 340, 200, 200, 200, 200},{ 340, -50, 200, 110, -30},{ 340, -90, 200, 0, -350}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 210, 10},{ 340, 40, 200, 120, -220},{ 340, 110, 200, 190, 30}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, 0, 210},{ 340, 200, 40, -150, 70},{ 340, 200, 90, -30, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 90, -100, 110},{ 340, 200, 90, 0, 110},{ 340, 200, 200, 200, 200},{ 340, 200, 90, 0, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 90, -30, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 80, -70, 150},{ 340, 200, -90, -390, 10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -30, 80},{ 340, 200, 40, -260, 140},{ 340, 200, 0, -10, 30}} +} +}, +/* GC....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +}, +{ /* noPair */ {{{{0}}}}, +/* GU....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 190, 80, 200},{ 340, 190, 180, 70, 200},{ 340, 100, 90, -20, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 220, 110, 200},{ 340, 280, 210, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 190, 180, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 90, -20, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 160, 50, 200},{ 340, 30, -80, -10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 270, 190, 180, 200},{ 340, 180, 70, 140, 200},{ 340, 220, 100, 180, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 230, 200, 230},{ 340, 170, 160, 200, 160},{ 340, 80, 170, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 210, 200, 210},{ 340, 200, 190, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 170, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 150, 210, 200, 210},{ 340, -90, 0, 200, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 200, 180},{ 340, 60, 150, 200, 150},{ 340, 90, 90, 200, 90}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 200, 130, 160},{ 340, 70, 200, 120, 50},{ 340, -20, 200, 30, 140},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 200, 170, 90},{ 340, 200, 200, 210, 180},{ 340, 200, 200, 200, 200},{ 340, 180, 200, 200, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, -20, 200, 30, 140},{ 340, 200, 200, 200, 200},{ 340, 50, 200, 110, 130},{ 340, -10, 200, -40, -210}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 180, 200, 200, 160},{ 340, 140, 200, 110, -60},{ 340, 180, 200, 150, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 60, 190},{ 340, 200, 160, -50, 80},{ 340, 200, 170, 40, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 210, 0, 130},{ 340, 200, 190, 80, 110},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 70, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, 40, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 40, 170},{ 340, 200, 0, -310, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 70, 100},{ 340, 200, 150, -160, 160},{ 340, 200, 90, 60, 10}} +} +}, +/* GU....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 200, 90, 200},{ 340, 190, 170, 60, 200},{ 340, 10, 0, -110, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 170, 60, 200},{ 340, 250, 170, 160, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 70, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 60, -50, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 160, 50, 200},{ 340, 0, -120, -50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 250, 180, 170, 200},{ 340, 40, -80, -10, 200},{ 340, 210, 100, 170, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 240, 200, 240},{ 340, 160, 160, 200, 160},{ 340, -10, 80, 200, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 150, 200, 150},{ 340, 160, 160, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 60, 60, 200, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 140, 200, 140},{ 340, 200, 200, 200, 200},{ 340, 150, 210, 200, 210},{ 340, -130, -30, 200, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 160, 200, 160},{ 340, -90, 10, 200, 10},{ 340, 90, 80, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 200, 140, 170},{ 340, 60, 200, 120, 40},{ 340, -110, 200, -60, 50},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 200, 110, 40},{ 340, 160, 200, 180, 140},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 80, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, -50, 200, 0, 110},{ 340, 200, 200, 200, 200},{ 340, 50, 200, 110, 130},{ 340, -50, 200, -70, -250}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 180, 150},{ 340, -10, 200, -30, -210},{ 340, 170, 200, 140, 150}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 70, 200},{ 340, 200, 160, -50, 80},{ 340, 200, 80, -50, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, -60, 70},{ 340, 200, 160, 50, 80},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -50, -20}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 140, 10, 150},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 40, 170},{ 340, 200, -30, -350, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 160, 50, 80},{ 340, 200, 10, -310, 10},{ 340, 200, 80, 50, 0}} +} +}, +/* GU....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 250, 240, 130, 200},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 250, 140, 200},{ 340, 310, 230, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 190, 80, 200},{ 340, 130, 20, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 230, 120, 190, 200},{ 340, 270, 150, 220, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 230, 220, 200, 220},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 230, 200, 230},{ 340, 220, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 180, 240, 200, 240},{ 340, 10, 100, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 110, 200, 200, 200},{ 340, 140, 140, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 130, 200, 180, 110},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 200, 190, 120},{ 340, 220, 200, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 140, 160},{ 340, 90, 200, 70, -110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 190, 200, 160, -10},{ 340, 220, 200, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 220, 10, 140},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 20, 150},{ 340, 200, 220, 100, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 100, -210, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 200, -110, 200},{ 340, 200, 140, 110, 60}} +} +}, +/* GU....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 230, 220, 110, 200},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 340, 260, 250, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 260, 250, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 200, 90, 200},{ 340, 100, -20, 50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 220, 110, 180, 200},{ 340, 290, 180, 250, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 210, 200, 200, 200},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 250, 200, 250},{ 340, 250, 250, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 250, 250, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 190, 240, 200, 240},{ 340, -30, 70, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 100, 190, 200, 190},{ 340, 170, 160, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 110, 200, 160, 90},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 130},{ 340, 250, 200, 270, 230},{ 340, 200, 200, 200, 200},{ 340, 250, 200, 270, 230}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 140, 170},{ 340, 50, 200, 30, -150}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 180, 200, 150, -20},{ 340, 250, 200, 220, 230}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 200, -10, 120},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 30, 170},{ 340, 200, 250, 130, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 130, 170}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 70, -250, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 190, -120, 190},{ 340, 200, 160, 130, 80}} +} +}, +/* GU....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 250, 240, 130, 200},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 250, 140, 200},{ 340, 310, 230, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 190, 80, 200},{ 340, 130, 20, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 230, 120, 190, 200},{ 340, 270, 150, 220, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 230, 220, 200, 220},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 230, 200, 230},{ 340, 220, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 180, 240, 200, 240},{ 340, 10, 100, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 110, 200, 200, 200},{ 340, 140, 140, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 130, 200, 180, 110},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 200, 190, 120},{ 340, 220, 200, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 140, 160},{ 340, 90, 200, 70, -110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 190, 200, 160, -10},{ 340, 220, 200, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 220, 10, 140},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 20, 150},{ 340, 200, 220, 100, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 100, -210, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 200, -110, 200},{ 340, 200, 140, 110, 60}} +} +}, +/* GU....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 230, 220, 110, 200},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 340, 260, 250, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 260, 250, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 200, 90, 200},{ 340, 100, -20, 50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 220, 110, 180, 200},{ 340, 290, 180, 250, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 210, 200, 200, 200},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 250, 200, 250},{ 340, 250, 250, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 250, 250, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 190, 240, 200, 240},{ 340, -30, 70, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 100, 190, 200, 190},{ 340, 170, 160, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 110, 200, 160, 90},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 130},{ 340, 250, 200, 270, 230},{ 340, 200, 200, 200, 200},{ 340, 250, 200, 270, 230}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 140, 170},{ 340, 50, 200, 30, -150}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 180, 200, 150, -20},{ 340, 250, 200, 220, 230}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 200, -10, 120},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 30, 170},{ 340, 200, 250, 130, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 130, 170}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 70, -250, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 190, -120, 190},{ 340, 200, 160, 130, 80}} +} +}, +/* GU....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +}, +{ /* noPair */ {{{{0}}}}, +/* UG....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 100, 200},{ 340, 190, 190, 90, 200},{ 340, 100, 100, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 240, 130, 200},{ 340, 280, 220, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 210, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 100, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 70, 200},{ 340, 30, -70, 10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 270, 210, 200, 200},{ 340, 180, 80, 160, 200},{ 340, 220, 120, 190, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 260, 200, 230},{ 340, 150, 190, 200, 160},{ 340, 60, 200, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 240, 200, 210},{ 340, 180, 220, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 160, 210, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 200, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 130, 240, 200, 210},{ 340, -110, 30, 200, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 210, 200, 180},{ 340, 40, 180, 200, 150},{ 340, 70, 120, 200, 90}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 140, 150},{ 340, 90, 200, 130, 40},{ 340, 0, 200, 40, 130},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 200, 170, 80},{ 340, 220, 200, 220, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 200, 150}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 40, 130},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 110, 120},{ 340, 10, 200, -30, -220}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 200, 150},{ 340, 160, 200, 120, -70},{ 340, 190, 200, 150, 150}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, 20, 220},{ 340, 200, 190, -90, 110},{ 340, 200, 200, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, -40, 150},{ 340, 200, 220, 40, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 0, 190},{ 340, 200, 30, -350, 30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120},{ 340, 200, 180, -200, 180},{ 340, 200, 120, 20, 30}} +} +}, +/* UG....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 210, 110, 200},{ 340, 190, 190, 80, 200},{ 340, 10, 10, -90, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 180, 80, 200},{ 340, 250, 190, 180, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 90, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 70, -30, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 70, 200},{ 340, 0, -100, -30, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 250, 190, 190, 200},{ 340, 40, -60, 10, 200},{ 340, 210, 110, 190, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 270, 200, 240},{ 340, 140, 190, 200, 160},{ 340, -30, 110, 200, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 180, 200, 150},{ 340, 140, 190, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 40, 90, 200, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 170, 200, 140},{ 340, 200, 200, 200, 200},{ 340, 130, 240, 200, 210},{ 340, -150, 0, 200, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 150, 190, 200, 160},{ 340, -110, 40, 200, 10},{ 340, 70, 110, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 200, 150, 160},{ 340, 80, 200, 120, 30},{ 340, -90, 200, -50, 40},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 200, 120, 30},{ 340, 180, 200, 180, 130},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 80, 40}}, +{{ 340, 340, 340, 340, 340},{ 340, -30, 200, 10, 100},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 110, 120},{ 340, -30, 200, -70, -260}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 190, 200, 190, 140},{ 340, 10, 200, -30, -220},{ 340, 190, 200, 150, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 230},{ 340, 200, 190, -90, 100},{ 340, 200, 110, -90, 110},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 180, -100, 100},{ 340, 200, 190, 10, 100},{ 340, 200, 200, 200, 200},{ 340, 200, 90, -90, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, -30, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 0, 190},{ 340, 200, 0, -390, -10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 190, 10, 110},{ 340, 200, 40, -350, 30},{ 340, 200, 110, 10, 30}} +} +}, +/* UG....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 250, 250, 150, 200},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 260, 160, 200},{ 340, 310, 250, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 100, 200},{ 340, 130, 30, 110, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 230, 130, 210, 200},{ 340, 270, 170, 240, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 210, 250, 200, 220},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 220, 260, 200, 230},{ 340, 200, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 160, 270, 200, 240},{ 340, -10, 130, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 90, 230, 200, 200},{ 340, 120, 170, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 150, 200, 190, 100},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 200, 200, 110},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200},{ 340, 100, 200, 140, 150},{ 340, 110, 200, 70, -120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 210, 200, 170, -20},{ 340, 240, 200, 200, 190}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 250, -30, 170},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, -20, 180},{ 340, 200, 250, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 220},{ 340, 200, 130, -250, 130}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 230, -150, 230},{ 340, 200, 170, 70, 80}} +} +}, +/* UG....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 230, 230, 130, 200},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 340, 280, 270, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 280, 270, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 110, 200},{ 340, 100, 0, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 220, 120, 200, 200},{ 340, 290, 190, 270, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 190, 230, 200, 200},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 280, 200, 250},{ 340, 230, 280, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 230, 280, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 170, 270, 200, 240},{ 340, -50, 100, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 80, 220, 200, 190},{ 340, 150, 190, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 130, 200, 170, 80},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 120},{ 340, 270, 200, 270, 220},{ 340, 200, 200, 200, 200},{ 340, 270, 200, 270, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200},{ 340, 110, 200, 150, 160},{ 340, 70, 200, 30, -160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 160, -30},{ 340, 270, 200, 230, 220}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 230, -50, 150},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 280, 0, 190},{ 340, 200, 280, 100, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 280, 100, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 230},{ 340, 200, 100, -290, 90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 220, -160, 220},{ 340, 200, 190, 90, 110}} +} +}, +/* UG....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 250, 250, 150, 200},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 260, 160, 200},{ 340, 310, 250, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 100, 200},{ 340, 130, 30, 110, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 230, 130, 210, 200},{ 340, 270, 170, 240, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 210, 250, 200, 220},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 220, 260, 200, 230},{ 340, 200, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 160, 270, 200, 240},{ 340, -10, 130, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 90, 230, 200, 200},{ 340, 120, 170, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 150, 200, 190, 100},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 200, 200, 110},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200},{ 340, 100, 200, 140, 150},{ 340, 110, 200, 70, -120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 210, 200, 170, -20},{ 340, 240, 200, 200, 190}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 250, -30, 170},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, -20, 180},{ 340, 200, 250, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 220},{ 340, 200, 130, -250, 130}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 230, -150, 230},{ 340, 200, 170, 70, 80}} +} +}, +/* UG....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 230, 230, 130, 200},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 340, 280, 270, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 280, 270, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 110, 200},{ 340, 100, 0, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 220, 120, 200, 200},{ 340, 290, 190, 270, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 190, 230, 200, 200},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 280, 200, 250},{ 340, 230, 280, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 230, 280, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 170, 270, 200, 240},{ 340, -50, 100, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 80, 220, 200, 190},{ 340, 150, 190, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 130, 200, 170, 80},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 120},{ 340, 270, 200, 270, 220},{ 340, 200, 200, 200, 200},{ 340, 270, 200, 270, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200},{ 340, 110, 200, 150, 160},{ 340, 70, 200, 30, -160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 160, -30},{ 340, 270, 200, 230, 220}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 230, -50, 150},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 280, 0, 190},{ 340, 200, 280, 100, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 280, 100, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 230},{ 340, 200, 100, -290, 90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 220, -160, 220},{ 340, 200, 190, 90, 110}} +} +}, +/* UG....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +}, +{ /* noPair */ {{{{0}}}}, +/* AU....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 190, 80, 200},{ 340, 190, 180, 70, 200},{ 340, 100, 90, -20, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 220, 110, 200},{ 340, 280, 210, 200, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 190, 180, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 90, -20, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 160, 50, 200},{ 340, 30, -80, -10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 270, 190, 180, 200},{ 340, 180, 70, 140, 200},{ 340, 220, 100, 180, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 230, 200, 230},{ 340, 170, 160, 200, 160},{ 340, 80, 170, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 210, 200, 210},{ 340, 200, 190, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 170, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 150, 210, 200, 210},{ 340, -90, 0, 200, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 200, 180},{ 340, 60, 150, 200, 150},{ 340, 90, 90, 200, 90}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 200, 130, 160},{ 340, 70, 200, 120, 50},{ 340, -20, 200, 30, 140},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 200, 170, 90},{ 340, 200, 200, 210, 180},{ 340, 200, 200, 200, 200},{ 340, 180, 200, 200, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, -20, 200, 30, 140},{ 340, 200, 200, 200, 200},{ 340, 50, 200, 110, 130},{ 340, -10, 200, -40, -210}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 180, 200, 200, 160},{ 340, 140, 200, 110, -60},{ 340, 180, 200, 150, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 60, 190},{ 340, 200, 160, -50, 80},{ 340, 200, 170, 40, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 210, 0, 130},{ 340, 200, 190, 80, 110},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 70, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, 40, 180},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 40, 170},{ 340, 200, 0, -310, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 180, 70, 100},{ 340, 200, 150, -160, 160},{ 340, 200, 90, 60, 10}} +} +}, +/* AU....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 200, 90, 200},{ 340, 190, 170, 60, 200},{ 340, 10, 0, -110, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 170, 60, 200},{ 340, 250, 170, 160, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 70, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 60, -50, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 160, 50, 200},{ 340, 0, -120, -50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 250, 180, 170, 200},{ 340, 40, -80, -10, 200},{ 340, 210, 100, 170, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 240, 200, 240},{ 340, 160, 160, 200, 160},{ 340, -10, 80, 200, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 150, 200, 150},{ 340, 160, 160, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 60, 60, 200, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 140, 200, 140},{ 340, 200, 200, 200, 200},{ 340, 150, 210, 200, 210},{ 340, -130, -30, 200, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 160, 200, 160},{ 340, -90, 10, 200, 10},{ 340, 90, 80, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 90, 200, 140, 170},{ 340, 60, 200, 120, 40},{ 340, -110, 200, -60, 50},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 200, 110, 40},{ 340, 160, 200, 180, 140},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 80, 50}}, +{{ 340, 340, 340, 340, 340},{ 340, -50, 200, 0, 110},{ 340, 200, 200, 200, 200},{ 340, 50, 200, 110, 130},{ 340, -50, 200, -70, -250}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 170, 200, 180, 150},{ 340, -10, 200, -30, -210},{ 340, 170, 200, 140, 150}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 70, 200},{ 340, 200, 160, -50, 80},{ 340, 200, 80, -50, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 150, -60, 70},{ 340, 200, 160, 50, 80},{ 340, 200, 200, 200, 200},{ 340, 200, 60, -50, -20}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 140, 10, 150},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 40, 170},{ 340, 200, -30, -350, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 160, 50, 80},{ 340, 200, 10, -310, 10},{ 340, 200, 80, 50, 0}} +} +}, +/* AU....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 250, 240, 130, 200},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 250, 140, 200},{ 340, 310, 230, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 190, 80, 200},{ 340, 130, 20, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 230, 120, 190, 200},{ 340, 270, 150, 220, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 230, 220, 200, 220},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 230, 200, 230},{ 340, 220, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 180, 240, 200, 240},{ 340, 10, 100, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 110, 200, 200, 200},{ 340, 140, 140, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 130, 200, 180, 110},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 200, 190, 120},{ 340, 220, 200, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 140, 160},{ 340, 90, 200, 70, -110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 190, 200, 160, -10},{ 340, 220, 200, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 220, 10, 140},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 20, 150},{ 340, 200, 220, 100, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 100, -210, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 200, -110, 200},{ 340, 200, 140, 110, 60}} +} +}, +/* AU....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 230, 220, 110, 200},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 340, 260, 250, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 260, 250, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 200, 90, 200},{ 340, 100, -20, 50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 220, 110, 180, 200},{ 340, 290, 180, 250, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 210, 200, 200, 200},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 250, 200, 250},{ 340, 250, 250, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 250, 250, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 190, 240, 200, 240},{ 340, -30, 70, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 100, 190, 200, 190},{ 340, 170, 160, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 110, 200, 160, 90},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 130},{ 340, 250, 200, 270, 230},{ 340, 200, 200, 200, 200},{ 340, 250, 200, 270, 230}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 140, 170},{ 340, 50, 200, 30, -150}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 180, 200, 150, -20},{ 340, 250, 200, 220, 230}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 200, -10, 120},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 30, 170},{ 340, 200, 250, 130, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 130, 170}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 70, -250, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 190, -120, 190},{ 340, 200, 160, 130, 80}} +} +}, +/* AU....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 250, 240, 130, 200},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 250, 140, 200},{ 340, 310, 230, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 140, 30, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 190, 80, 200},{ 340, 130, 20, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 230, 120, 190, 200},{ 340, 270, 150, 220, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 230, 220, 200, 220},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 230, 200, 230},{ 340, 220, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 220, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 180, 240, 200, 240},{ 340, 10, 100, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 110, 200, 200, 200},{ 340, 140, 140, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 130, 200, 180, 110},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 200, 190, 120},{ 340, 220, 200, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 200, 80, 190},{ 340, 200, 200, 200, 200},{ 340, 80, 200, 140, 160},{ 340, 90, 200, 70, -110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 190, 200, 160, -10},{ 340, 220, 200, 200, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 220, 10, 140},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 230, 20, 150},{ 340, 200, 220, 100, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 220, 90, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 100, -210, 110}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 200, -110, 200},{ 340, 200, 140, 110, 60}} +} +}, +/* AU....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 230, 220, 110, 200},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 260, 150, 200},{ 340, 340, 260, 250, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 260, 250, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 160, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 200, 90, 200},{ 340, 100, -20, 50, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 230, 220, 200},{ 340, 220, 110, 180, 200},{ 340, 290, 180, 250, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 310, 200, 310},{ 340, 210, 200, 200, 200},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 250, 250, 200, 250},{ 340, 250, 250, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 250, 250, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 240, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 190, 240, 200, 240},{ 340, -30, 70, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 220, 200, 220},{ 340, 100, 190, 200, 190},{ 340, 170, 160, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 230},{ 340, 110, 200, 160, 90},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 200, 210, 130},{ 340, 250, 200, 270, 230},{ 340, 200, 200, 200, 200},{ 340, 250, 200, 270, 230}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 100, 210},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 140, 170},{ 340, 50, 200, 30, -150}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 220, 200, 240, 200},{ 340, 180, 200, 150, -20},{ 340, 250, 200, 220, 230}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 310, 130, 270},{ 340, 200, 200, -10, 120},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 30, 170},{ 340, 200, 250, 130, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 130, 170}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, 110, 240},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 70, 200},{ 340, 200, 70, -250, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 220, 100, 140},{ 340, 200, 190, -120, 190},{ 340, 200, 160, 130, 80}} +} +}, +/* AU....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +}, +{ /* noPair */ {{{{0}}}}, +/* UA....CG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 100, 200},{ 340, 190, 190, 90, 200},{ 340, 100, 100, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 240, 240, 130, 200},{ 340, 280, 220, 220, 200},{ 340, 200, 200, 200, 200},{ 340, 270, 210, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 100, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 70, 200},{ 340, 30, -70, 10, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 270, 210, 200, 200},{ 340, 180, 80, 160, 200},{ 340, 220, 120, 190, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 260, 200, 230},{ 340, 150, 190, 200, 160},{ 340, 60, 200, 200, 170},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 190, 240, 200, 210},{ 340, 180, 220, 200, 190},{ 340, 200, 200, 200, 200},{ 340, 160, 210, 200, 180}}, +{{ 340, 340, 340, 340, 340},{ 340, 60, 200, 200, 170},{ 340, 200, 200, 200, 200},{ 340, 130, 240, 200, 210},{ 340, -110, 30, 200, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 160, 210, 200, 180},{ 340, 40, 180, 200, 150},{ 340, 70, 120, 200, 90}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 100, 200, 140, 150},{ 340, 90, 200, 130, 40},{ 340, 0, 200, 40, 130},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 200, 170, 80},{ 340, 220, 200, 220, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 200, 150}}, +{{ 340, 340, 340, 340, 340},{ 340, 0, 200, 40, 130},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 110, 120},{ 340, 10, 200, -30, -220}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 200, 200, 150},{ 340, 160, 200, 120, -70},{ 340, 190, 200, 150, 150}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, 20, 220},{ 340, 200, 190, -90, 110},{ 340, 200, 200, 0, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 240, -40, 150},{ 340, 200, 220, 40, 140},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 0, 200},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 0, 190},{ 340, 200, 30, -350, 30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 210, 30, 120},{ 340, 200, 180, -200, 180},{ 340, 200, 120, 20, 30}} +} +}, +/* UA....GC */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 210, 210, 110, 200},{ 340, 190, 190, 80, 200},{ 340, 10, 10, -90, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 180, 180, 80, 200},{ 340, 250, 190, 180, 200},{ 340, 200, 200, 200, 200},{ 340, 150, 90, 90, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 70, -30, 200},{ 340, 200, 200, 200, 200},{ 340, 180, 180, 70, 200},{ 340, 0, -100, -30, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 250, 190, 190, 200},{ 340, 40, -60, 10, 200},{ 340, 210, 110, 190, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 270, 200, 240},{ 340, 140, 190, 200, 160},{ 340, -30, 110, 200, 80},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 140, 180, 200, 150},{ 340, 140, 190, 200, 160},{ 340, 200, 200, 200, 200},{ 340, 40, 90, 200, 60}}, +{{ 340, 340, 340, 340, 340},{ 340, 30, 170, 200, 140},{ 340, 200, 200, 200, 200},{ 340, 130, 240, 200, 210},{ 340, -150, 0, 200, -30}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 150, 190, 200, 160},{ 340, -110, 40, 200, 10},{ 340, 70, 110, 200, 80}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 200, 150, 160},{ 340, 80, 200, 120, 30},{ 340, -90, 200, -50, 40},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 80, 200, 120, 30},{ 340, 180, 200, 180, 130},{ 340, 200, 200, 200, 200},{ 340, 90, 200, 80, 40}}, +{{ 340, 340, 340, 340, 340},{ 340, -30, 200, 10, 100},{ 340, 200, 200, 200, 200},{ 340, 70, 200, 110, 120},{ 340, -30, 200, -70, -260}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 190, 200, 190, 140},{ 340, 10, 200, -30, -220},{ 340, 190, 200, 150, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 30, 230},{ 340, 200, 190, -90, 100},{ 340, 200, 110, -90, 110},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 180, -100, 100},{ 340, 200, 190, 10, 100},{ 340, 200, 200, 200, 200},{ 340, 200, 90, -90, 0}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 170, -30, 170},{ 340, 200, 200, 200, 200},{ 340, 200, 240, 0, 190},{ 340, 200, 0, -390, -10}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 190, 10, 110},{ 340, 200, 40, -350, 30},{ 340, 200, 110, 10, 30}} +} +}, +/* UA....GU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 250, 250, 150, 200},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 260, 160, 200},{ 340, 310, 250, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 100, 200},{ 340, 130, 30, 110, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 230, 130, 210, 200},{ 340, 270, 170, 240, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 210, 250, 200, 220},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 220, 260, 200, 230},{ 340, 200, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 160, 270, 200, 240},{ 340, -10, 130, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 90, 230, 200, 200},{ 340, 120, 170, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 150, 200, 190, 100},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 200, 200, 110},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200},{ 340, 100, 200, 140, 150},{ 340, 110, 200, 70, -120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 210, 200, 170, -20},{ 340, 240, 200, 200, 190}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 250, -30, 170},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, -20, 180},{ 340, 200, 250, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 220},{ 340, 200, 130, -250, 130}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 230, -150, 230},{ 340, 200, 170, 70, 80}} +} +}, +/* UA....UG */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 230, 230, 130, 200},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 340, 280, 270, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 280, 270, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 110, 200},{ 340, 100, 0, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 220, 120, 200, 200},{ 340, 290, 190, 270, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 190, 230, 200, 200},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 280, 200, 250},{ 340, 230, 280, 200, 250},{ 340, 200, 200, 200, 200},{ 340, 230, 280, 200, 250}}, +{{ 340, 340, 340, 340, 340},{ 340, 130, 270, 200, 240},{ 340, 200, 200, 200, 200},{ 340, 170, 270, 200, 240},{ 340, -50, 100, 200, 70}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 80, 220, 200, 190},{ 340, 150, 190, 200, 160}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 130, 200, 170, 80},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 120},{ 340, 270, 200, 270, 220},{ 340, 200, 200, 200, 200},{ 340, 270, 200, 270, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 70, 200, 110, 200},{ 340, 200, 200, 200, 200},{ 340, 110, 200, 150, 160},{ 340, 70, 200, 30, -160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 160, -30},{ 340, 270, 200, 230, 220}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 230, -50, 150},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 280, 0, 190},{ 340, 200, 280, 100, 190},{ 340, 200, 200, 200, 200},{ 340, 200, 280, 100, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 270, 70, 270},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 230},{ 340, 200, 100, -290, 90}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 220, -160, 220},{ 340, 200, 190, 90, 110}} +} +}, +/* UA....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 250, 250, 150, 200},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 260, 260, 160, 200},{ 340, 310, 250, 240, 200},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 150, 150, 50, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 100, 200},{ 340, 130, 30, 110, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 230, 130, 210, 200},{ 340, 270, 170, 240, 200}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 230, 340, 200, 310},{ 340, 210, 250, 200, 220},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 220, 260, 200, 230},{ 340, 200, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220}}, +{{ 340, 340, 340, 340, 340},{ 340, 110, 250, 200, 220},{ 340, 200, 200, 200, 200},{ 340, 160, 270, 200, 240},{ 340, -10, 130, 200, 100}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 200, 220},{ 340, 90, 230, 200, 200},{ 340, 120, 170, 200, 140}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 200, 210, 220},{ 340, 150, 200, 190, 100},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 160, 200, 200, 110},{ 340, 240, 200, 240, 190},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190}}, +{{ 340, 340, 340, 340, 340},{ 340, 50, 200, 90, 180},{ 340, 200, 200, 200, 200},{ 340, 100, 200, 140, 150},{ 340, 110, 200, 70, -120}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 240, 200, 240, 190},{ 340, 210, 200, 170, -20},{ 340, 240, 200, 200, 190}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 340, 100, 290},{ 340, 200, 250, -30, 170},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 260, -20, 180},{ 340, 200, 250, 70, 160},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 250, 50, 250},{ 340, 200, 200, 200, 200},{ 340, 200, 270, 30, 220},{ 340, 200, 130, -250, 130}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 200, 250, 70, 160},{ 340, 200, 230, -150, 230},{ 340, 200, 170, 70, 80}} +} +}, +/* UA....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 230, 230, 130, 200},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 280, 280, 170, 200},{ 340, 340, 280, 270, 200},{ 340, 200, 200, 200, 200},{ 340, 340, 280, 270, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 170, 170, 70, 200},{ 340, 200, 200, 200, 200},{ 340, 210, 210, 110, 200},{ 340, 100, 0, 70, 200}}, +{{ 340, 340, 340, 340, 340},{ 340, 200, 200, 200, 200},{ 340, 310, 250, 240, 200},{ 340, 220, 120, 200, 200},{ 340, 290, 190, 270, 200}} +}, 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340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +}, +/* ??....AU */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +}, +/* ??....UA */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +}, +/* ??....?? */ +{{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +}, +{ +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}}, +{{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340},{ 340, 340, 340, 340, 340}} +} +} +} +}; + +PUBLIC int int22_H[NBPAIRS+1][NBPAIRS+1][5][5][5][5] = +{ /* noPair */ {{{{{0}}}}}, +{ /* noPair */ {{{{0}}}}, +/* CG.@@..CG */ +{ { { { 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..CG */ +{ { 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* CG.@C..CG */ +{ { 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* CG.@G..CG */ +{ { 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* CG.@U..CG */ +{ { 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* CG.A@..CG */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..CG */ +{{ DEF,-1029, -949,-1029,-1029}, +{-1079,-2058,-1978,-2058,-2058}, +{ -569,-1548,-1468,-1548,-1548}, +{ -989,-1968,-1888,-1968,-1968}, +{ -859,-1838,-1758,-1838,-1838}}, +/* CG.AC..CG */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -999,-1978,-1898,-1978,-1978}, +{ -499,-1478,-1398,-1478,-1478}, +{ -989,-1968,-1888,-1968,-1968}, +{ -789,-1768,-1688,-1768,-1768}}, +/* CG.AG..CG */ +{{ DEF,-1029, -949,-1029,-1029}, +{-1079,-2058,-1978,-2058,-2058}, +{ -569,-1548,-1468,-1548,-1548}, +{ -989,-1968,-1888,-1968,-1968}, +{ -859,-1838,-1758,-1838,-1838}}, +/* CG.AU..CG */ +{{ DEF,-1029, -949,-1029,-1029}, +{-1079,-2058,-1978,-2058,-2058}, +{ -719,-1698,-1618,-1698,-1698}, +{ -989,-1968,-1888,-1968,-1968}, +{ -909,-1888,-1808,-1888,-1888}}}, +/* CG.C@..CG */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..CG */ +{{ DEF, -519, -449, -519, -669}, +{-1079,-1548,-1478,-1548,-1698}, +{ -569,-1038, -968,-1038,-1188}, +{ -989,-1458,-1388,-1458,-1608}, +{ -859,-1328,-1258,-1328,-1478}}, +/* CG.CC..CG */ +{{ DEF, -519, -449, -519, -669}, +{ -999,-1468,-1398,-1468,-1618}, +{ -499, -968, -898, -968,-1118}, +{ -989,-1458,-1388,-1458,-1608}, +{ -789,-1258,-1188,-1258,-1408}}, +/* CG.CG..CG */ +{{ DEF, -519, -449, -519, -669}, +{-1079,-1548,-1478,-1548,-1698}, +{ -569,-1038, -968,-1038,-1188}, +{ -989,-1458,-1388,-1458,-1608}, +{ -859,-1328,-1258,-1328,-1478}}, +/* CG.CU..CG */ +{{ DEF, -519, -449, -519, -669}, +{-1079,-1548,-1478,-1548,-1698}, +{ -719,-1188,-1118,-1188,-1338}, +{ -989,-1458,-1388,-1458,-1608}, +{ -909,-1378,-1308,-1378,-1528}}}, +/* CG.G@..CG */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..CG */ +{{ DEF, -939, -939, -939, -939}, +{-1079,-1968,-1968,-1968,-1968}, +{ -569,-1458,-1458,-1458,-1458}, +{ -989,-1878,-1878,-1878,-1878}, +{ -859,-1748,-1748,-1748,-1748}}, +/* CG.GC..CG */ +{{ DEF, -939, -939, -939, -939}, +{ -999,-1888,-1888,-1888,-1888}, +{ -499,-1388,-1388,-1388,-1388}, +{ -989,-1878,-1878,-1878,-1878}, +{ -789,-1678,-1678,-1678,-1678}}, +/* CG.GG..CG */ +{{ DEF, -939, -939, -939, -939}, +{-1079,-1968,-1968,-1968,-1968}, +{ -569,-1458,-1458,-1458,-1458}, +{ -989,-1878,-1878,-1878,-1878}, +{ -859,-1748,-1748,-1748,-1748}}, +/* CG.GU..CG */ +{{ DEF, -939, -939, -939, -939}, +{-1079,-1968,-1968,-1968,-1968}, +{ -719,-1608,-1608,-1608,-1608}, +{ -989,-1878,-1878,-1878,-1878}, +{ -909,-1798,-1798,-1798,-1798}}}, +/* CG.U@..CG */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..CG */ +{{ DEF, -809, -739, -809, -859}, +{-1079,-1838,-1768,-1838,-1888}, +{ -569,-1328,-1258,-1328,-1378}, +{ -989,-1748,-1678,-1748,-1798}, +{ -859,-1618,-1548,-1618,-1668}}, +/* CG.UC..CG */ +{{ DEF, -809, -739, -809, -859}, +{ -999,-1758,-1688,-1758,-1808}, +{ -499,-1258,-1188,-1258,-1308}, +{ -989,-1748,-1678,-1748,-1798}, +{ -789,-1548,-1478,-1548,-1598}}, +/* CG.UG..CG */ +{{ DEF, -809, -739, -809, -859}, +{-1079,-1838,-1768,-1838,-1888}, +{ -569,-1328,-1258,-1328,-1378}, +{ -989,-1748,-1678,-1748,-1798}, +{ -859,-1618,-1548,-1618,-1668}}, +/* CG.UU..CG */ +{{ DEF, -809, -739, -809, -859}, +{-1079,-1838,-1768,-1838,-1888}, +{ -719,-1478,-1408,-1478,-1528}, +{ -989,-1748,-1678,-1748,-1798}, +{ -909,-1668,-1598,-1668,-1718}}}}, +/* CG.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* CG.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* CG.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* CG.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* CG.A@..GC */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..GC */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -569,-1548,-1468,-1548,-1548}, +{ -769,-1748,-1668,-1748,-1748}, +{ -759,-1738,-1658,-1738,-1738}, +{ -549,-1528,-1448,-1528,-1528}}, +/* CG.AC..GC */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -929,-1908,-1828,-1908,-1908}, +{ -359,-1338,-1258,-1338,-1338}, +{ -789,-1768,-1688,-1768,-1768}, +{ -549,-1528,-1448,-1528,-1528}}, +/* CG.AG..GC */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -609,-1588,-1508,-1588,-1588}, +{ -359,-1338,-1258,-1338,-1338}, +{ -669,-1648,-1568,-1648,-1648}, +{ -549,-1528,-1448,-1528,-1528}}, +/* CG.AU..GC */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -929,-1908,-1828,-1908,-1908}, +{ -439,-1418,-1338,-1418,-1418}, +{ -789,-1768,-1688,-1768,-1768}, +{ -619,-1598,-1518,-1598,-1598}}}, +/* CG.C@..GC */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..GC */ +{{ DEF, -519, -449, -519, -669}, +{ -569,-1038, -968,-1038,-1188}, +{ -769,-1238,-1168,-1238,-1388}, +{ -759,-1228,-1158,-1228,-1378}, +{ -549,-1018, -948,-1018,-1168}}, +/* CG.CC..GC */ +{{ DEF, -519, -449, -519, -669}, +{ -929,-1398,-1328,-1398,-1548}, +{ -359, -828, -758, -828, -978}, +{ -789,-1258,-1188,-1258,-1408}, +{ -549,-1018, -948,-1018,-1168}}, +/* CG.CG..GC */ +{{ DEF, -519, -449, -519, -669}, +{ -609,-1078,-1008,-1078,-1228}, +{ -359, -828, -758, -828, -978}, +{ -669,-1138,-1068,-1138,-1288}, +{ -549,-1018, -948,-1018,-1168}}, +/* CG.CU..GC */ +{{ DEF, -519, -449, -519, -669}, +{ -929,-1398,-1328,-1398,-1548}, +{ -439, -908, -838, -908,-1058}, +{ -789,-1258,-1188,-1258,-1408}, +{ -619,-1088,-1018,-1088,-1238}}}, +/* CG.G@..GC */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..GC */ +{{ DEF, -939, -939, -939, -939}, +{ -569,-1458,-1458,-1458,-1458}, +{ -769,-1658,-1658,-1658,-1658}, +{ -759,-1648,-1648,-1648,-1648}, +{ -549,-1438,-1438,-1438,-1438}}, +/* CG.GC..GC */ +{{ DEF, -939, -939, -939, -939}, +{ -929,-1818,-1818,-1818,-1818}, +{ -359,-1248,-1248,-1248,-1248}, +{ -789,-1678,-1678,-1678,-1678}, +{ -549,-1438,-1438,-1438,-1438}}, +/* CG.GG..GC */ +{{ DEF, -939, -939, -939, -939}, +{ -609,-1498,-1498,-1498,-1498}, +{ -359,-1248,-1248,-1248,-1248}, +{ -669,-1558,-1558,-1558,-1558}, +{ -549,-1438,-1438,-1438,-1438}}, +/* CG.GU..GC */ +{{ DEF, -939, -939, -939, -939}, +{ -929,-1818,-1818,-1818,-1818}, +{ -439,-1328,-1328,-1328,-1328}, +{ -789,-1678,-1678,-1678,-3080}, +{ -619,-1508,-1508,-1508,-1508}}}, +/* CG.U@..GC */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..GC */ +{{ DEF, -809, -739, -809, -859}, +{ -569,-1328,-1258,-1328,-1378}, +{ -769,-1528,-1458,-1528,-1578}, +{ -759,-1518,-1448,-1518,-1568}, +{ -549,-1308,-1238,-1308,-1358}}, +/* CG.UC..GC */ +{{ DEF, -809, -739, -809, -859}, +{ -929,-1688,-1618,-1688,-1738}, +{ -359,-1118,-1048,-1118,-1168}, +{ -789,-1548,-1478,-1548,-1598}, +{ -549,-1308,-1238,-1308,-1358}}, +/* CG.UG..GC */ +{{ DEF, -809, -739, -809, -859}, +{ -609,-1368,-1298,-1368,-1418}, +{ -359,-1118,-1048,-1118,-1168}, +{ -669,-1428,-1358,-1428,-1478}, +{ -549,-1308,-1238,-1308,-1358}}, +/* CG.UU..GC */ +{{ DEF, -809, -739, -809, -859}, +{ -929,-1688,-1618,-1688,-1738}, +{ -439,-1198,-1128,-1198,-1248}, +{ -789,-1548,-1478,-1548,-1598}, +{ -619,-1378,-1308,-1378,-1428}}}}, +/* CG.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* CG.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* CG.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* CG.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* CG.A@..GU */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..GU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -479,-1458,-1378,-1458,-1458}, +{ -309,-1288,-1208,-1288,-1288}, +{ -389,-1368,-1288,-1368,-1368}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AC..GU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AG..GU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AU..GU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}}, +/* CG.C@..GU */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..GU */ +{{ DEF, -519, -449, -519, -669}, +{ -479, -948, -878, -948,-1098}, +{ -309, -778, -708, -778, -928}, +{ -389, -858, -788, -858,-1008}, +{ -379, -848, -778, -848, -998}}, +/* CG.CC..GU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}, +/* CG.CG..GU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}, +/* CG.CU..GU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}}, +/* CG.G@..GU */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..GU */ +{{ DEF, -939, -939, -939, -939}, +{ -479,-1368,-1368,-1368,-1368}, +{ -309,-1198,-1198,-1198,-1198}, +{ -389,-1278,-1278,-1278,-1278}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GC..GU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GG..GU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GU..GU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}}, +/* CG.U@..GU */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..GU */ +{{ DEF, -809, -739, -809, -859}, +{ -479,-1238,-1168,-1238,-1288}, +{ -309,-1068, -998,-1068,-1118}, +{ -389,-1148,-1078,-1148,-1198}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UC..GU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UG..GU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UU..GU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}}}, +/* CG.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* CG.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* CG.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* CG.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* CG.A@..UG */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..UG */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -769,-1748,-1668,-1748,-1748}, +{ -529,-1508,-1428,-1508,-1508}, +{ -709,-1688,-1608,-1688,-1688}, +{ -599,-1578,-1498,-1578,-1578}}, +/* CG.AC..UG */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -839,-1818,-1738,-1818,-1818}, +{ -529,-1508,-1428,-1508,-1508}, +{ -859,-1838,-1758,-1838,-1838}, +{ -489,-1468,-1388,-1468,-1468}}, +/* CG.AG..UG */ +{{ DEF,-1029, -949,-1029,-1029}, +{-1009,-1988,-1908,-1988,-1988}, +{ -409,-1388,-1308,-1388,-1388}, +{ -969,-1948,-1868,-1948,-1948}, +{ -599,-1578,-1498,-1578,-1578}}, +/* CG.AU..UG */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -859,-1838,-1758,-1838,-1838}, +{ -529,-1508,-1428,-1508,-1508}, +{ -859,-1838,-1758,-1838,-1838}, +{ -409,-1388,-1308,-1388,-1388}}}, +/* CG.C@..UG */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..UG */ +{{ DEF, -519, -449, -519, -669}, +{ -769,-1238,-1168,-1238,-1388}, +{ -529, -998, -928, -998,-1148}, +{ -709,-1178,-1108,-1178,-1328}, +{ -599,-1068, -998,-1068,-1218}}, +/* CG.CC..UG */ +{{ DEF, -519, -449, -519, -669}, +{ -839,-1308,-1238,-1308,-1458}, +{ -529, -998, -928, -998,-1148}, +{ -859,-1328,-1258,-1328,-1478}, +{ -489, -958, -888, -958,-1108}}, +/* CG.CG..UG */ +{{ DEF, -519, -449, -519, -669}, +{-1009,-1478,-1408,-1478,-1628}, +{ -409, -878, -808, -878,-1028}, +{ -969,-1438,-1368,-1438,-1588}, +{ -599,-1068, -998,-1068,-1218}}, +/* CG.CU..UG */ +{{ DEF, -519, -449, -519, -669}, +{ -859,-1328,-1258,-1328,-1478}, +{ -529, -998, -928, -998,-1148}, +{ -859,-1328,-1258,-1328,-1478}, +{ -409, -878, -808, -878,-1028}}}, +/* CG.G@..UG */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..UG */ +{{ DEF, -939, -939, -939, -939}, +{ -769,-1658,-1658,-1658,-1658}, +{ -529,-1418,-1418,-1418,-1418}, +{ -709,-1598,-1598,-1598,-1598}, +{ -599,-1488,-1488,-1488,-1488}}, +/* CG.GC..UG */ +{{ DEF, -939, -939, -939, -939}, +{ -839,-1728,-1728,-1728,-1728}, +{ -529,-1418,-1418,-1418,-1418}, +{ -859,-1748,-1748,-1748,-1748}, +{ -489,-1378,-1378,-1378,-1378}}, +/* CG.GG..UG */ +{{ DEF, -939, -939, -939, -939}, +{-1009,-1898,-1898,-1898,-1898}, +{ -409,-1298,-1298,-1298,-1298}, +{ -969,-1858,-1858,-1858,-1858}, +{ -599,-1488,-1488,-1488,-1488}}, +/* CG.GU..UG */ +{{ DEF, -939, -939, -939, -939}, +{ -859,-1748,-1748,-1748,-1748}, +{ -529,-1418,-1418,-1418,-1418}, +{ -859,-1748,-1748,-1748,-1748}, +{ -409,-1298,-1298,-1298,-1298}}}, +/* CG.U@..UG */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..UG */ +{{ DEF, -809, -739, -809, -859}, +{ -769,-1528,-1458,-1528,-1578}, +{ -529,-1288,-1218,-1288,-1338}, +{ -709,-1468,-1398,-1468,-1518}, +{ -599,-1358,-1288,-1358,-1408}}, +/* CG.UC..UG */ +{{ DEF, -809, -739, -809, -859}, +{ -839,-1598,-1528,-1598,-1648}, +{ -529,-1288,-1218,-1288,-1338}, +{ -859,-1618,-1548,-1618,-1668}, +{ -489,-1248,-1178,-1248,-1298}}, +/* CG.UG..UG */ +{{ DEF, -809, -739, -809, -859}, +{-1009,-1768,-1698,-1768,-1818}, +{ -409,-1168,-1098,-1168,-1218}, +{ -969,-1728,-1658,-1728,-1778}, +{ -599,-1358,-1288,-1358,-1408}}, +/* CG.UU..UG */ +{{ DEF, -809, -739, -809, -859}, +{ -859,-1618,-1548,-1618,-1668}, +{ -529,-1288,-1218,-1288,-1338}, +{ -859,-1618,-1548,-1618,-1668}, +{ -409,-1168,-1098,-1168,-1218}}}}, +/* CG.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* CG.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* CG.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* CG.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* CG.A@..AU */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..AU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -479,-1458,-1378,-1458,-1458}, +{ -309,-1288,-1208,-1288,-1288}, +{ -389,-1368,-1288,-1368,-1368}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AC..AU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AG..AU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}, +/* CG.AU..AU */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -649,-1628,-1548,-1628,-1628}, +{ -289,-1268,-1188,-1268,-1268}, +{ -739,-1718,-1638,-1718,-1718}, +{ -379,-1358,-1278,-1358,-1358}}}, +/* CG.C@..AU */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..AU */ +{{ DEF, -519, -449, -519, -669}, +{ -479, -948, -878, -948,-1098}, +{ -309, -778, -708, -778, -928}, +{ -389, -858, -788, -858,-1008}, +{ -379, -848, -778, -848, -998}}, +/* CG.CC..AU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}, +/* CG.CG..AU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}, +/* CG.CU..AU */ +{{ DEF, -519, -449, -519, -669}, +{ -649,-1118,-1048,-1118,-1268}, +{ -289, -758, -688, -758, -908}, +{ -739,-1208,-1138,-1208,-1358}, +{ -379, -848, -778, -848, -998}}}, +/* CG.G@..AU */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..AU */ +{{ DEF, -939, -939, -939, -939}, +{ -479,-1368,-1368,-1368,-1368}, +{ -309,-1198,-1198,-1198,-1198}, +{ -389,-1278,-1278,-1278,-1278}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GC..AU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GG..AU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}, +/* CG.GU..AU */ +{{ DEF, -939, -939, -939, -939}, +{ -649,-1538,-1538,-1538,-1538}, +{ -289,-1178,-1178,-1178,-1178}, +{ -739,-1628,-1628,-1628,-1628}, +{ -379,-1268,-1268,-1268,-1268}}}, +/* CG.U@..AU */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..AU */ +{{ DEF, -809, -739, -809, -859}, +{ -479,-1238,-1168,-1238,-1288}, +{ -309,-1068, -998,-1068,-1118}, +{ -389,-1148,-1078,-1148,-1198}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UC..AU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UG..AU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}, +/* CG.UU..AU */ +{{ DEF, -809, -739, -809, -859}, +{ -649,-1408,-1338,-1408,-1458}, +{ -289,-1048, -978,-1048,-1098}, +{ -739,-1498,-1428,-1498,-1548}, +{ -379,-1138,-1068,-1138,-1188}}}}, +/* CG.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* CG.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* CG.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* CG.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* CG.A@..UA */ +{{{ DEF,-1029, -949,-1029,-1029}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA..UA */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -449,-1428,-1348,-1428,-1428}, +{ -479,-1458,-1378,-1458,-1458}, +{ -429,-1408,-1328,-1408,-1408}, +{ -329,-1308,-1228,-1308,-1308}}, +/* CG.AC..UA */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -679,-1658,-1578,-1658,-1658}, +{ -559,-1538,-1458,-1538,-1538}, +{ -729,-1708,-1628,-1708,-1708}, +{ -189,-1168,-1088,-1168,-1168}}, +/* CG.AG..UA */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -939,-1918,-1838,-1918,-1918}, +{ -249,-1228,-1148,-1228,-1228}, +{ -939,-1918,-1838,-1918,-1918}, +{ -329,-1308,-1228,-1308,-1308}}, +/* CG.AU..UA */ +{{ DEF,-1029, -949,-1029,-1029}, +{ -639,-1618,-1538,-1618,-1618}, +{ -229,-1208,-1128,-1208,-1208}, +{ -729,-1708,-1628,-1708,-1708}, +{ -190,-1169,-1089,-1169,-1169}}}, +/* CG.C@..UA */ +{{{ DEF, -519, -449, -519, -669}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA..UA */ +{{ DEF, -519, -449, -519, -669}, +{ -449, -918, -848, -918,-1068}, +{ -479, -948, -878, -948,-1098}, +{ -429, -898, -828, -898,-1048}, +{ -329, -798, -728, -798, -948}}, +/* CG.CC..UA */ +{{ DEF, -519, -449, -519, -669}, +{ -679,-1148,-1078,-1148,-1298}, +{ -559,-1028, -958,-1028,-1178}, +{ -729,-1198,-1128,-1198,-1348}, +{ -189, -658, -588, -658, -808}}, +/* CG.CG..UA */ +{{ DEF, -519, -449, -519, -669}, +{ -939,-1408,-1338,-1408,-1558}, +{ -249, -718, -648, -718, -868}, +{ -939,-1408,-1338,-1408,-1558}, +{ -329, -798, -728, -798, -948}}, +/* CG.CU..UA */ +{{ DEF, -519, -449, -519, -669}, +{ -639,-1108,-1038,-1108,-1258}, +{ -229, -698, -628, -698, -848}, +{ -729,-1198,-1128,-1198,-1348}, +{ -190, -659, -589, -659, -809}}}, +/* CG.G@..UA */ +{{{ DEF, -939, -939, -939, -939}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA..UA */ +{{ DEF, -939, -939, -939, -939}, +{ -449,-1338,-1338,-1338,-1338}, +{ -479,-1368,-1368,-1368,-1368}, +{ -429,-1318,-1318,-1318,-1318}, +{ -329,-1218,-1218,-1218,-1218}}, +/* CG.GC..UA */ +{{ DEF, -939, -939, -939, -939}, +{ -679,-1568,-1568,-1568,-1568}, +{ -559,-1448,-1448,-1448,-1448}, +{ -729,-1618,-1618,-1618,-1618}, +{ -189,-1078,-1078,-1078,-1078}}, +/* CG.GG..UA */ +{{ DEF, -939, -939, -939, -939}, +{ -939,-1828,-1828,-1828,-1828}, +{ -249,-1138,-1138,-1138,-1138}, +{ -939,-1828,-1828,-1828,-1828}, +{ -329,-1218,-1218,-1218,-1218}}, +/* CG.GU..UA */ +{{ DEF, -939, -939, -939, -939}, +{ -639,-1528,-1528,-1528,-1528}, +{ -229,-1118,-1118,-1118,-1118}, +{ -729,-1618,-1618,-1618,-1618}, +{ -190,-1079,-1079,-1079,-1079}}}, +/* CG.U@..UA */ +{{{ DEF, -809, -739, -809, -859}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA..UA */ +{{ DEF, -809, -739, -809, -859}, +{ -449,-1208,-1138,-1208,-1258}, +{ -479,-1238,-1168,-1238,-1288}, +{ -429,-1188,-1118,-1188,-1238}, +{ -329,-1088,-1018,-1088,-1138}}, +/* CG.UC..UA */ +{{ DEF, -809, -739, -809, -859}, +{ -679,-1438,-1368,-1438,-1488}, +{ -559,-1318,-1248,-1318,-1368}, +{ -729,-1488,-1418,-1488,-1538}, +{ -189, -948, -878, -948, -998}}, +/* CG.UG..UA */ +{{ DEF, -809, -739, -809, -859}, +{ -939,-1698,-1628,-1698,-1748}, +{ -249,-1008, -938,-1008,-1058}, +{ -939,-1698,-1628,-1698,-1748}, +{ -329,-1088,-1018,-1088,-1138}}, +/* CG.UU..UA */ +{{ DEF, -809, -739, -809, -859}, +{ -639,-1398,-1328,-1398,-1448}, +{ -229, -988, -918, -988,-1038}, +{ -729,-1488,-1418,-1488,-1538}, +{ -190, -949, -879, -949, -999}}}}, +/* CG.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* CG.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* CG.A@.. @ */ +{{{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AA.. @ */ +{{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AC.. @ */ +{{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AG.. @ */ +{{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}, +/* CG.AU.. @ */ +{{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}, +{ -100,-1079, -999,-1079,-1079}}}, +/* CG.C@.. @ */ +{{{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CA.. @ */ +{{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CC.. @ */ +{{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CG.. @ */ +{{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}, +/* CG.CU.. @ */ +{{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}, +{ -100, -569, -499, -569, -719}}}, +/* CG.G@.. @ */ +{{{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GA.. @ */ +{{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GC.. @ */ +{{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GG.. @ */ +{{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}, +/* CG.GU.. @ */ +{{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}, +{ -100, -989, -989, -989, -989}}}, +/* CG.U@.. @ */ +{{{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UA.. @ */ +{{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UC.. @ */ +{{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UG.. @ */ +{{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}, +/* CG.UU.. @ */ +{{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}, +{ -100, -859, -789, -859, -909}}}}}, +{ /* noPair */ {{{{0}}}}, +/* GC.@@..CG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* GC.@C..CG */ +{{ 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* GC.@G..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* GC.@U..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* GC.A@..CG */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..CG */ +{{ DEF, -519, -879, -559, -879}, +{-1079,-1548,-1908,-1588,-1908}, +{ -569,-1038,-1398,-1078,-1398}, +{ -989,-1458,-1818,-1498,-1818}, +{ -859,-1328,-1688,-1368,-1688}}, +/* GC.AC..CG */ +{{ DEF, -519, -879, -559, -879}, +{ -999,-1468,-1828,-1508,-1828}, +{ -499, -968,-1328,-1008,-1328}, +{ -989,-1458,-1818,-1498,-1818}, +{ -789,-1258,-1618,-1298,-1618}}, +/* GC.AG..CG */ +{{ DEF, -519, -879, -559, -879}, +{-1079,-1548,-1908,-1588,-1908}, +{ -569,-1038,-1398,-1078,-1398}, +{ -989,-1458,-1818,-1498,-1818}, +{ -859,-1328,-1688,-1368,-1688}}, +/* GC.AU..CG */ +{{ DEF, -519, -879, -559, -879}, +{-1079,-1548,-1908,-1588,-1908}, +{ -719,-1188,-1548,-1228,-1548}, +{ -989,-1458,-1818,-1498,-1818}, +{ -909,-1378,-1738,-1418,-1738}}}, +/* GC.C@..CG */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..CG */ +{{ DEF, -719, -309, -309, -389}, +{-1079,-1748,-1338,-1338,-1418}, +{ -569,-1238, -828, -828, -908}, +{ -989,-1658,-1248,-1248,-1328}, +{ -859,-1528,-1118,-1118,-1198}}, +/* GC.CC..CG */ +{{ DEF, -719, -309, -309, -389}, +{ -999,-1668,-1258,-1258,-1338}, +{ -499,-1168, -758, -758, -838}, +{ -989,-1658,-1248,-1248,-1328}, +{ -789,-1458,-1048,-1048,-1128}}, +/* GC.CG..CG */ +{{ DEF, -719, -309, -309, -389}, +{-1079,-1748,-1338,-1338,-1418}, +{ -569,-1238, -828, -828, -908}, +{ -989,-1658,-1248,-1248,-1328}, +{ -859,-1528,-1118,-1118,-1198}}, +/* GC.CU..CG */ +{{ DEF, -719, -309, -309, -389}, +{-1079,-1748,-1338,-1338,-1418}, +{ -719,-1388, -978, -978,-1058}, +{ -989,-1658,-1248,-1248,-1328}, +{ -909,-1578,-1168,-1168,-1248}}}, +/* GC.G@..CG */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..CG */ +{{ DEF, -709, -739, -619, -739}, +{-1079,-1738,-1768,-1648,-1768}, +{ -569,-1228,-1258,-1138,-1258}, +{ -989,-1648,-1678,-1558,-1678}, +{ -859,-1518,-1548,-1428,-1548}}, +/* GC.GC..CG */ +{{ DEF, -709, -739, -619, -739}, +{ -999,-1658,-1688,-1568,-1688}, +{ -499,-1158,-1188,-1068,-1188}, +{ -989,-1648,-1678,-1558,-1678}, +{ -789,-1448,-1478,-1358,-1478}}, +/* GC.GG..CG */ +{{ DEF, -709, -739, -619, -739}, +{-1079,-1738,-1768,-1648,-1768}, +{ -569,-1228,-1258,-1138,-1258}, +{ -989,-1648,-1678,-1558,-1678}, +{ -859,-1518,-1548,-1428,-1548}}, +/* GC.GU..CG */ +{{ DEF, -709, -739, -619, -739}, +{-1079,-1738,-1768,-1648,-1768}, +{ -719,-1378,-1408,-1288,-1408}, +{ -989,-1648,-1678,-1558,-3080}, +{ -909,-1568,-1598,-1478,-1598}}}, +/* GC.U@..CG */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..CG */ +{{ DEF, -499, -499, -499, -569}, +{-1079,-1528,-1528,-1528,-1598}, +{ -569,-1018,-1018,-1018,-1088}, +{ -989,-1438,-1438,-1438,-1508}, +{ -859,-1308,-1308,-1308,-1378}}, +/* GC.UC..CG */ +{{ DEF, -499, -499, -499, -569}, +{ -999,-1448,-1448,-1448,-1518}, +{ -499, -948, -948, -948,-1018}, +{ -989,-1438,-1438,-1438,-1508}, +{ -789,-1238,-1238,-1238,-1308}}, +/* GC.UG..CG */ +{{ DEF, -499, -499, -499, -569}, +{-1079,-1528,-1528,-1528,-1598}, +{ -569,-1018,-1018,-1018,-1088}, +{ -989,-1438,-1438,-1438,-1508}, +{ -859,-1308,-1308,-1308,-1378}}, +/* GC.UU..CG */ +{{ DEF, -499, -499, -499, -569}, +{-1079,-1528,-1528,-1528,-1598}, +{ -719,-1168,-1168,-1168,-1238}, +{ -989,-1438,-1438,-1438,-1508}, +{ -909,-1358,-1358,-1358,-1428}}}}, +/* GC.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* GC.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* GC.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* GC.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* GC.A@..GC */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..GC */ +{{ DEF, -519, -879, -559, -879}, +{ -569,-1038,-1398,-1078,-1398}, +{ -769,-1238,-1598,-1278,-1598}, +{ -759,-1228,-1588,-1268,-1588}, +{ -549,-1018,-1378,-1058,-1378}}, +/* GC.AC..GC */ +{{ DEF, -519, -879, -559, -879}, +{ -929,-1398,-1758,-1438,-1758}, +{ -359, -828,-1188, -868,-1188}, +{ -789,-1258,-1618,-1298,-1618}, +{ -549,-1018,-1378,-1058,-1378}}, +/* GC.AG..GC */ +{{ DEF, -519, -879, -559, -879}, +{ -609,-1078,-1438,-1118,-1438}, +{ -359, -828,-1188, -868,-1188}, +{ -669,-1138,-1498,-1178,-1498}, +{ -549,-1018,-1378,-1058,-1378}}, +/* GC.AU..GC */ +{{ DEF, -519, -879, -559, -879}, +{ -929,-1398,-1758,-1438,-1758}, +{ -439, -908,-1268, -948,-1268}, +{ -789,-1258,-1618,-1298,-1618}, +{ -619,-1088,-1448,-1128,-1448}}}, +/* GC.C@..GC */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..GC */ +{{ DEF, -719, -309, -309, -389}, +{ -569,-1238, -828, -828, -908}, +{ -769,-1438,-1028,-1028,-1108}, +{ -759,-1428,-1018,-1018,-1098}, +{ -549,-1218, -808, -808, -888}}, +/* GC.CC..GC */ +{{ DEF, -719, -309, -309, -389}, +{ -929,-1598,-1188,-1188,-1268}, +{ -359,-1028, -618, -618, -698}, +{ -789,-1458,-1048,-1048,-1128}, +{ -549,-1218, -808, -808, -888}}, +/* GC.CG..GC */ +{{ DEF, -719, -309, -309, -389}, +{ -609,-1278, -868, -868, -948}, +{ -359,-1028, -618, -618, -698}, +{ -669,-1338, -928, -928,-1008}, +{ -549,-1218, -808, -808, -888}}, +/* GC.CU..GC */ +{{ DEF, -719, -309, -309, -389}, +{ -929,-1598,-1188,-1188,-1268}, +{ -439,-1108, -698, -698, -778}, +{ -789,-1458,-1048,-1048,-1128}, +{ -619,-1288, -878, -878, -958}}}, +/* GC.G@..GC */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..GC */ +{{ DEF, -709, -739, -619, -739}, +{ -569,-1228,-1258,-1138,-1258}, +{ -769,-1428,-1458,-1338,-1458}, +{ -759,-1418,-1448,-1328,-1448}, +{ -549,-1208,-1238,-1118,-1238}}, +/* GC.GC..GC */ +{{ DEF, -709, -739, -619, -739}, +{ -929,-1588,-1618,-1498,-1618}, +{ -359,-1018,-1048, -928,-1048}, +{ -789,-1448,-1478,-1358,-1478}, +{ -549,-1208,-1238,-1118,-1238}}, +/* GC.GG..GC */ +{{ DEF, -709, -739, -619, -739}, +{ -609,-1268,-1298,-1178,-1298}, +{ -359,-1018,-1048, -928,-1048}, +{ -669,-1328,-1358,-1238,-1358}, +{ -549,-1208,-1238,-1118,-1238}}, +/* GC.GU..GC */ +{{ DEF, -709, -739, -619, -739}, +{ -929,-1588,-1618,-1498,-1618}, +{ -439,-1098,-1128,-1008,-1128}, +{ -789,-1448,-1478,-1358,-3080}, +{ -619,-1278,-1308,-1188,-1308}}}, +/* GC.U@..GC */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..GC */ +{{ DEF, -499, -499, -499, -569}, +{ -569,-1018,-1018,-1018,-1088}, +{ -769,-1218,-1218,-1218,-1288}, +{ -759,-1208,-1208,-1208,-1278}, +{ -549, -998, -998, -998,-1068}}, +/* GC.UC..GC */ +{{ DEF, -499, -499, -499, -569}, +{ -929,-1378,-1378,-1378,-1448}, +{ -359, -808, -808, -808, -878}, +{ -789,-1238,-1238,-1238,-1308}, +{ -549, -998, -998, -998,-1068}}, +/* GC.UG..GC */ +{{ DEF, -499, -499, -499, -569}, +{ -609,-1058,-1058,-1058,-1128}, +{ -359, -808, -808, -808, -878}, +{ -669,-1118,-1118,-1118,-1188}, +{ -549, -998, -998, -998,-1068}}, +/* GC.UU..GC */ +{{ DEF, -499, -499, -499, -569}, +{ -929,-1378,-1378,-1378,-1448}, +{ -439, -888, -888, -888, -958}, +{ -789,-1238,-1238,-1238,-1308}, +{ -619,-1068,-1068,-1068,-1138}}}}, +/* GC.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* GC.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GC.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GC.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* GC.A@..GU */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..GU */ +{{ DEF, -519, -879, -559, -879}, +{ -479, -948,-1308, -988,-1308}, +{ -309, -778,-1138, -818,-1138}, +{ -389, -858,-1218, -898,-1218}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AC..GU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AG..GU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AU..GU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}}, +/* GC.C@..GU */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..GU */ +{{ DEF, -719, -309, -309, -389}, +{ -479,-1148, -738, -738, -818}, +{ -309, -978, -568, -568, -648}, +{ -389,-1058, -648, -648, -728}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CC..GU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CG..GU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CU..GU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}}, +/* GC.G@..GU */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..GU */ +{{ DEF, -709, -739, -619, -739}, +{ -479,-1138,-1168,-1048,-1168}, +{ -309, -968, -998, -878, -998}, +{ -389,-1048,-1078, -958,-1078}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GC..GU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GG..GU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GU..GU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}}, +/* GC.U@..GU */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..GU */ +{{ DEF, -499, -499, -499, -569}, +{ -479, -928, -928, -928, -998}, +{ -309, -758, -758, -758, -828}, +{ -389, -838, -838, -838, -908}, +{ -379, -828, -828, -828, -898}}, +/* GC.UC..GU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}, +/* GC.UG..GU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}, +/* GC.UU..GU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}}}, +/* GC.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* GC.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* GC.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* GC.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* GC.A@..UG */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..UG */ +{{ DEF, -519, -879, -559, -879}, +{ -769,-1238,-1598,-1278,-1598}, +{ -529, -998,-1358,-1038,-1358}, +{ -709,-1178,-1538,-1218,-1538}, +{ -599,-1068,-1428,-1108,-1428}}, +/* GC.AC..UG */ +{{ DEF, -519, -879, -559, -879}, +{ -839,-1308,-1668,-1348,-1668}, +{ -529, -998,-1358,-1038,-1358}, +{ -859,-1328,-1688,-1368,-1688}, +{ -489, -958,-1318, -998,-1318}}, +/* GC.AG..UG */ +{{ DEF, -519, -879, -559, -879}, +{-1009,-1478,-1838,-1518,-1838}, +{ -409, -878,-1238, -918,-1238}, +{ -969,-1438,-1798,-1478,-1798}, +{ -599,-1068,-1428,-1108,-1428}}, +/* GC.AU..UG */ +{{ DEF, -519, -879, -559, -879}, +{ -859,-1328,-1688,-1368,-1688}, +{ -529, -998,-1358,-1038,-1358}, +{ -859,-1328,-1688,-1368,-1688}, +{ -409, -878,-1238, -918,-1238}}}, +/* GC.C@..UG */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..UG */ +{{ DEF, -719, -309, -309, -389}, +{ -769,-1438,-1028,-1028,-1108}, +{ -529,-1198, -788, -788, -868}, +{ -709,-1378, -968, -968,-1048}, +{ -599,-1268, -858, -858, -938}}, +/* GC.CC..UG */ +{{ DEF, -719, -309, -309, -389}, +{ -839,-1508,-1098,-1098,-1178}, +{ -529,-1198, -788, -788, -868}, +{ -859,-1528,-1118,-1118,-1198}, +{ -489,-1158, -748, -748, -828}}, +/* GC.CG..UG */ +{{ DEF, -719, -309, -309, -389}, +{-1009,-1678,-1268,-1268,-1348}, +{ -409,-1078, -668, -668, -748}, +{ -969,-1638,-1228,-1228,-1308}, +{ -599,-1268, -858, -858, -938}}, +/* GC.CU..UG */ +{{ DEF, -719, -309, -309, -389}, +{ -859,-1528,-1118,-1118,-1198}, +{ -529,-1198, -788, -788, -868}, +{ -859,-1528,-1118,-1118,-1198}, +{ -409,-1078, -668, -668, -748}}}, +/* GC.G@..UG */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..UG */ +{{ DEF, -709, -739, -619, -739}, +{ -769,-1428,-1458,-1338,-1458}, +{ -529,-1188,-1218,-1098,-1218}, +{ -709,-1368,-1398,-1278,-1398}, +{ -599,-1258,-1288,-1168,-1288}}, +/* GC.GC..UG */ +{{ DEF, -709, -739, -619, -739}, +{ -839,-1498,-1528,-1408,-1528}, +{ -529,-1188,-1218,-1098,-1218}, +{ -859,-1518,-1548,-1428,-1548}, +{ -489,-1148,-1178,-1058,-1178}}, +/* GC.GG..UG */ +{{ DEF, -709, -739, -619, -739}, +{-1009,-1668,-1698,-1578,-1698}, +{ -409,-1068,-1098, -978,-1098}, +{ -969,-1628,-1658,-1538,-1658}, +{ -599,-1258,-1288,-1168,-1288}}, +/* GC.GU..UG */ +{{ DEF, -709, -739, -619, -739}, +{ -859,-1518,-1548,-1428,-1548}, +{ -529,-1188,-1218,-1098,-1218}, +{ -859,-1518,-1548,-1428,-1548}, +{ -409,-1068,-1098, -978,-1098}}}, +/* GC.U@..UG */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..UG */ +{{ DEF, -499, -499, -499, -569}, +{ -769,-1218,-1218,-1218,-1288}, +{ -529, -978, -978, -978,-1048}, +{ -709,-1158,-1158,-1158,-1228}, +{ -599,-1048,-1048,-1048,-1118}}, +/* GC.UC..UG */ +{{ DEF, -499, -499, -499, -569}, +{ -839,-1288,-1288,-1288,-1358}, +{ -529, -978, -978, -978,-1048}, +{ -859,-1308,-1308,-1308,-1378}, +{ -489, -938, -938, -938,-1008}}, +/* GC.UG..UG */ +{{ DEF, -499, -499, -499, -569}, +{-1009,-1458,-1458,-1458,-1528}, +{ -409, -858, -858, -858, -928}, +{ -969,-1418,-1418,-1418,-1488}, +{ -599,-1048,-1048,-1048,-1118}}, +/* GC.UU..UG */ +{{ DEF, -499, -499, -499, -569}, +{ -859,-1308,-1308,-1308,-1378}, +{ -529, -978, -978, -978,-1048}, +{ -859,-1308,-1308,-1308,-1378}, +{ -409, -858, -858, -858, -928}}}}, +/* GC.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* GC.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GC.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GC.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* GC.A@..AU */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..AU */ +{{ DEF, -519, -879, -559, -879}, +{ -479, -948,-1308, -988,-1308}, +{ -309, -778,-1138, -818,-1138}, +{ -389, -858,-1218, -898,-1218}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AC..AU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AG..AU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}, +/* GC.AU..AU */ +{{ DEF, -519, -879, -559, -879}, +{ -649,-1118,-1478,-1158,-1478}, +{ -289, -758,-1118, -798,-1118}, +{ -739,-1208,-1568,-1248,-1568}, +{ -379, -848,-1208, -888,-1208}}}, +/* GC.C@..AU */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..AU */ +{{ DEF, -719, -309, -309, -389}, +{ -479,-1148, -738, -738, -818}, +{ -309, -978, -568, -568, -648}, +{ -389,-1058, -648, -648, -728}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CC..AU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CG..AU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}, +/* GC.CU..AU */ +{{ DEF, -719, -309, -309, -389}, +{ -649,-1318, -908, -908, -988}, +{ -289, -958, -548, -548, -628}, +{ -739,-1408, -998, -998,-1078}, +{ -379,-1048, -638, -638, -718}}}, +/* GC.G@..AU */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..AU */ +{{ DEF, -709, -739, -619, -739}, +{ -479,-1138,-1168,-1048,-1168}, +{ -309, -968, -998, -878, -998}, +{ -389,-1048,-1078, -958,-1078}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GC..AU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GG..AU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}, +/* GC.GU..AU */ +{{ DEF, -709, -739, -619, -739}, +{ -649,-1308,-1338,-1218,-1338}, +{ -289, -948, -978, -858, -978}, +{ -739,-1398,-1428,-1308,-1428}, +{ -379,-1038,-1068, -948,-1068}}}, +/* GC.U@..AU */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..AU */ +{{ DEF, -499, -499, -499, -569}, +{ -479, -928, -928, -928, -998}, +{ -309, -758, -758, -758, -828}, +{ -389, -838, -838, -838, -908}, +{ -379, -828, -828, -828, -898}}, +/* GC.UC..AU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}, +/* GC.UG..AU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}, +/* GC.UU..AU */ +{{ DEF, -499, -499, -499, -569}, +{ -649,-1098,-1098,-1098,-1168}, +{ -289, -738, -738, -738, -808}, +{ -739,-1188,-1188,-1188,-1258}, +{ -379, -828, -828, -828, -898}}}}, +/* GC.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* GC.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* GC.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* GC.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* GC.A@..UA */ +{{{ DEF, -519, -879, -559, -879}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA..UA */ +{{ DEF, -519, -879, -559, -879}, +{ -449, -918,-1278, -958,-1278}, +{ -479, -948,-1308, -988,-1308}, +{ -429, -898,-1258, -938,-1258}, +{ -329, -798,-1158, -838,-1158}}, +/* GC.AC..UA */ +{{ DEF, -519, -879, -559, -879}, +{ -679,-1148,-1508,-1188,-1508}, +{ -559,-1028,-1388,-1068,-1388}, +{ -729,-1198,-1558,-1238,-1558}, +{ -189, -658,-1018, -698,-1018}}, +/* GC.AG..UA */ +{{ DEF, -519, -879, -559, -879}, +{ -939,-1408,-1768,-1448,-1768}, +{ -249, -718,-1078, -758,-1078}, +{ -939,-1408,-1768,-1448,-1768}, +{ -329, -798,-1158, -838,-1158}}, +/* GC.AU..UA */ +{{ DEF, -519, -879, -559, -879}, +{ -639,-1108,-1468,-1148,-1468}, +{ -229, -698,-1058, -738,-1058}, +{ -729,-1198,-1558,-1238,-1558}, +{ -190, -659,-1019, -699,-1019}}}, +/* GC.C@..UA */ +{{{ DEF, -719, -309, -309, -389}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA..UA */ +{{ DEF, -719, -309, -309, -389}, +{ -449,-1118, -708, -708, -788}, +{ -479,-1148, -738, -738, -818}, +{ -429,-1098, -688, -688, -768}, +{ -329, -998, -588, -588, -668}}, +/* GC.CC..UA */ +{{ DEF, -719, -309, -309, -389}, +{ -679,-1348, -938, -938,-1018}, +{ -559,-1228, -818, -818, -898}, +{ -729,-1398, -988, -988,-1068}, +{ -189, -858, -448, -448, -528}}, +/* GC.CG..UA */ +{{ DEF, -719, -309, -309, -389}, +{ -939,-1608,-1198,-1198,-1278}, +{ -249, -918, -508, -508, -588}, +{ -939,-1608,-1198,-1198,-1278}, +{ -329, -998, -588, -588, -668}}, +/* GC.CU..UA */ +{{ DEF, -719, -309, -309, -389}, +{ -639,-1308, -898, -898, -978}, +{ -229, -898, -488, -488, -568}, +{ -729,-1398, -988, -988,-1068}, +{ -190, -859, -449, -449, -529}}}, +/* GC.G@..UA */ +{{{ DEF, -709, -739, -619, -739}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA..UA */ +{{ DEF, -709, -739, -619, -739}, +{ -449,-1108,-1138,-1018,-1138}, +{ -479,-1138,-1168,-1048,-1168}, +{ -429,-1088,-1118, -998,-1118}, +{ -329, -988,-1018, -898,-1018}}, +/* GC.GC..UA */ +{{ DEF, -709, -739, -619, -739}, +{ -679,-1338,-1368,-1248,-1368}, +{ -559,-1218,-1248,-1128,-1248}, +{ -729,-1388,-1418,-1298,-1418}, +{ -189, -848, -878, -758, -878}}, +/* GC.GG..UA */ +{{ DEF, -709, -739, -619, -739}, +{ -939,-1598,-1628,-1508,-1628}, +{ -249, -908, -938, -818, -938}, +{ -939,-1598,-1628,-1508,-1628}, +{ -329, -988,-1018, -898,-1018}}, +/* GC.GU..UA */ +{{ DEF, -709, -739, -619, -739}, +{ -639,-1298,-1328,-1208,-1328}, +{ -229, -888, -918, -798, -918}, +{ -729,-1388,-1418,-1298,-1418}, +{ -190, -849, -879, -759, -879}}}, +/* GC.U@..UA */ +{{{ DEF, -499, -499, -499, -569}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA..UA */ +{{ DEF, -499, -499, -499, -569}, +{ -449, -898, -898, -898, -968}, +{ -479, -928, -928, -928, -998}, +{ -429, -878, -878, -878, -948}, +{ -329, -778, -778, -778, -848}}, +/* GC.UC..UA */ +{{ DEF, -499, -499, -499, -569}, +{ -679,-1128,-1128,-1128,-1198}, +{ -559,-1008,-1008,-1008,-1078}, +{ -729,-1178,-1178,-1178,-1248}, +{ -189, -638, -638, -638, -708}}, +/* GC.UG..UA */ +{{ DEF, -499, -499, -499, -569}, +{ -939,-1388,-1388,-1388,-1458}, +{ -249, -698, -698, -698, -768}, +{ -939,-1388,-1388,-1388,-1458}, +{ -329, -778, -778, -778, -848}}, +/* GC.UU..UA */ +{{ DEF, -499, -499, -499, -569}, +{ -639,-1088,-1088,-1088,-1158}, +{ -229, -678, -678, -678, -748}, +{ -729,-1178,-1178,-1178,-1248}, +{ -190, -639, -639, -639, -709}}}}, +/* GC.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GC.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* GC.A@.. @ */ +{{{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AA.. @ */ +{{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AC.. @ */ +{{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AG.. @ */ +{{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}, +/* GC.AU.. @ */ +{{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}, +{ -100, -569, -929, -609, -929}}}, +/* GC.C@.. @ */ +{{{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CA.. @ */ +{{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CC.. @ */ +{{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CG.. @ */ +{{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}, +/* GC.CU.. @ */ +{{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}, +{ -100, -769, -359, -359, -439}}}, +/* GC.G@.. @ */ +{{{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GA.. @ */ +{{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GC.. @ */ +{{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GG.. @ */ +{{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}, +/* GC.GU.. @ */ +{{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}, +{ -100, -759, -789, -669, -789}}}, +/* GC.U@.. @ */ +{{{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UA.. @ */ +{{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UC.. @ */ +{{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UG.. @ */ +{{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}, +/* GC.UU.. @ */ +{{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}, +{ -100, -549, -549, -549, -619}}}}}, +{ /* noPair */ {{{{0}}}}, +/* GU.@@..CG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* GU.@C..CG */ +{{ 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* GU.@G..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* GU.@U..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* GU.A@..CG */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -569, -948,-1118,-1118,-1118}, +{ -989,-1368,-1538,-1538,-1538}, +{ -859,-1238,-1408,-1408,-1408}}, +/* GU.AC..CG */ +{{ DEF, -429, -599, -599, -599}, +{ -999,-1378,-1548,-1548,-1548}, +{ -499, -878,-1048,-1048,-1048}, +{ -989,-1368,-1538,-1538,-1538}, +{ -789,-1168,-1338,-1338,-1338}}, +/* GU.AG..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -569, -948,-1118,-1118,-1118}, +{ -989,-1368,-1538,-1538,-1538}, +{ -859,-1238,-1408,-1408,-1408}}, +/* GU.AU..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -719,-1098,-1268,-1268,-1268}, +{ -989,-1368,-1538,-1538,-1538}, +{ -909,-1288,-1458,-1458,-1458}}}, +/* GU.C@..CG */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -569, -778, -758, -758, -758}, +{ -989,-1198,-1178,-1178,-1178}, +{ -859,-1068,-1048,-1048,-1048}}, +/* GU.CC..CG */ +{{ DEF, -259, -239, -239, -239}, +{ -999,-1208,-1188,-1188,-1188}, +{ -499, -708, -688, -688, -688}, +{ -989,-1198,-1178,-1178,-1178}, +{ -789, -998, -978, -978, -978}}, +/* GU.CG..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -569, -778, -758, -758, -758}, +{ -989,-1198,-1178,-1178,-1178}, +{ -859,-1068,-1048,-1048,-1048}}, +/* GU.CU..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -719, -928, -908, -908, -908}, +{ -989,-1198,-1178,-1178,-1178}, +{ -909,-1118,-1098,-1098,-1098}}}, +/* GU.G@..CG */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -569, -858,-1208,-1208,-1208}, +{ -989,-1278,-1628,-1628,-1628}, +{ -859,-1148,-1498,-1498,-1498}}, +/* GU.GC..CG */ +{{ DEF, -339, -689, -689, -689}, +{ -999,-1288,-1638,-1638,-1638}, +{ -499, -788,-1138,-1138,-1138}, +{ -989,-1278,-1628,-1628,-1628}, +{ -789,-1078,-1428,-1428,-1428}}, +/* GU.GG..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -569, -858,-1208,-1208,-1208}, +{ -989,-1278,-1628,-1628,-1628}, +{ -859,-1148,-1498,-1498,-1498}}, +/* GU.GU..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -719,-1008,-1358,-1358,-1358}, +{ -989,-1278,-1628,-1628,-1628}, +{ -909,-1198,-1548,-1548,-1548}}}, +/* GU.U@..CG */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -569, -848, -848, -848, -848}, +{ -989,-1268,-1268,-1268,-1268}, +{ -859,-1138,-1138,-1138,-1138}}, +/* GU.UC..CG */ +{{ DEF, -329, -329, -329, -329}, +{ -999,-1278,-1278,-1278,-1278}, +{ -499, -778, -778, -778, -778}, +{ -989,-1268,-1268,-1268,-1268}, +{ -789,-1068,-1068,-1068,-1068}}, +/* GU.UG..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -569, -848, -848, -848, -848}, +{ -989,-1268,-1268,-1268,-1268}, +{ -859,-1138,-1138,-1138,-1138}}, +/* GU.UU..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -719, -998, -998, -998, -998}, +{ -989,-1268,-1268,-1268,-1268}, +{ -909,-1188,-1188,-1188,-1188}}}}, +/* GU.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* GU.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* GU.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* GU.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* GU.A@..GC */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -569, -948,-1118,-1118,-1118}, +{ -769,-1148,-1318,-1318,-1318}, +{ -759,-1138,-1308,-1308,-1308}, +{ -549, -928,-1098,-1098,-1098}}, +/* GU.AC..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -929,-1308,-1478,-1478,-1478}, +{ -359, -738, -908, -908, -908}, +{ -789,-1168,-1338,-1338,-1338}, +{ -549, -928,-1098,-1098,-1098}}, +/* GU.AG..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -609, -988,-1158,-1158,-1158}, +{ -359, -738, -908, -908, -908}, +{ -669,-1048,-1218,-1218,-1218}, +{ -549, -928,-1098,-1098,-1098}}, +/* GU.AU..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -929,-1308,-1478,-1478,-1478}, +{ -439, -818, -988, -988, -988}, +{ -789,-1168,-1338,-1338,-1338}, +{ -619, -998,-1168,-1168,-1168}}}, +/* GU.C@..GC */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -569, -778, -758, -758, -758}, +{ -769, -978, -958, -958, -958}, +{ -759, -968, -948, -948, -948}, +{ -549, -758, -738, -738, -738}}, +/* GU.CC..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -929,-1138,-1118,-1118,-1118}, +{ -359, -568, -548, -548, -548}, +{ -789, -998, -978, -978, -978}, +{ -549, -758, -738, -738, -738}}, +/* GU.CG..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -609, -818, -798, -798, -798}, +{ -359, -568, -548, -548, -548}, +{ -669, -878, -858, -858, -858}, +{ -549, -758, -738, -738, -738}}, +/* GU.CU..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -929,-1138,-1118,-1118,-1118}, +{ -439, -648, -628, -628, -628}, +{ -789, -998, -978, -978, -978}, +{ -619, -828, -808, -808, -808}}}, +/* GU.G@..GC */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -569, -858,-1208,-1208,-1208}, +{ -769,-1058,-1408,-1408,-1408}, +{ -759,-1048,-1398,-1398,-1398}, +{ -549, -838,-1188,-1188,-1188}}, +/* GU.GC..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -929,-1218,-1568,-1568,-1568}, +{ -359, -648, -998, -998, -998}, +{ -789,-1078,-1428,-1428,-1428}, +{ -549, -838,-1188,-1188,-1188}}, +/* GU.GG..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -609, -898,-1248,-1248,-1248}, +{ -359, -648, -998, -998, -998}, +{ -669, -958,-1308,-1308,-1308}, +{ -549, -838,-1188,-1188,-1188}}, +/* GU.GU..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -929,-1218,-1568,-1568,-1568}, +{ -439, -728,-1078,-1078,-1078}, +{ -789,-1078,-1428,-1428,-1428}, +{ -619, -908,-1258,-1258,-1258}}}, +/* GU.U@..GC */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -569, -848, -848, -848, -848}, +{ -769,-1048,-1048,-1048,-1048}, +{ -759,-1038,-1038,-1038,-1038}, +{ -549, -828, -828, -828, -828}}, +/* GU.UC..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -929,-1208,-1208,-1208,-1208}, +{ -359, -638, -638, -638, -638}, +{ -789,-1068,-1068,-1068,-1068}, +{ -549, -828, -828, -828, -828}}, +/* GU.UG..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -609, -888, -888, -888, -888}, +{ -359, -638, -638, -638, -638}, +{ -669, -948, -948, -948, -948}, +{ -549, -828, -828, -828, -828}}, +/* GU.UU..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -929,-1208,-1208,-1208,-1208}, +{ -439, -718, -718, -718, -718}, +{ -789,-1068,-1068,-1068,-1068}, +{ -619, -898, -898, -898, -898}}}}, +/* GU.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* GU.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GU.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GU.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* GU.A@..GU */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -479, -858,-1028,-1028,-1028}, +{ -309, -688, -858, -858, -858}, +{ -389, -768, -938, -938, -938}, +{ -379, -758, -928, -928, -928}}, +/* GU.AC..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* GU.AG..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* GU.AU..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}}, +/* GU.C@..GU */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -479, -688, -668, -668, -668}, +{ -309, -518, -498, -498, -498}, +{ -389, -598, -578, -578, -578}, +{ -379, -588, -568, -568, -568}}, +/* GU.CC..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* GU.CG..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* GU.CU..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}}, +/* GU.G@..GU */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -479, -768,-1118,-1118,-1118}, +{ -309, -598, -948, -948, -948}, +{ -389, -678,-1028,-1028,-1028}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GC..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GG..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GU..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}}, +/* GU.U@..GU */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -479, -758, -758, -758, -758}, +{ -309, -588, -588, -588, -588}, +{ -389, -668, -668, -668, -668}, +{ -379, -658, -658, -658, -658}}, +/* GU.UC..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* GU.UG..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* GU.UU..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}}}, +/* GU.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* GU.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* GU.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* GU.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* GU.A@..UG */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -769,-1148,-1318,-1318,-1318}, +{ -529, -908,-1078,-1078,-1078}, +{ -709,-1088,-1258,-1258,-1258}, +{ -599, -978,-1148,-1148,-1148}}, +/* GU.AC..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -839,-1218,-1388,-1388,-1388}, +{ -529, -908,-1078,-1078,-1078}, +{ -859,-1238,-1408,-1408,-1408}, +{ -489, -868,-1038,-1038,-1038}}, +/* GU.AG..UG */ +{{ DEF, -429, -599, -599, -599}, +{-1009,-1388,-1558,-1558,-1558}, +{ -409, -788, -958, -958, -958}, +{ -969,-1348,-1518,-1518,-1518}, +{ -599, -978,-1148,-1148,-1148}}, +/* GU.AU..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -859,-1238,-1408,-1408,-1408}, +{ -529, -908,-1078,-1078,-1078}, +{ -859,-1238,-1408,-1408,-1408}, +{ -409, -788, -958, -958, -958}}}, +/* GU.C@..UG */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -769, -978, -958, -958, -958}, +{ -529, -738, -718, -718, -718}, +{ -709, -918, -898, -898, -898}, +{ -599, -808, -788, -788, -788}}, +/* GU.CC..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -839,-1048,-1028,-1028,-1028}, +{ -529, -738, -718, -718, -718}, +{ -859,-1068,-1048,-1048,-1048}, +{ -489, -698, -678, -678, -678}}, +/* GU.CG..UG */ +{{ DEF, -259, -239, -239, -239}, +{-1009,-1218,-1198,-1198,-1198}, +{ -409, -618, -598, -598, -598}, +{ -969,-1178,-1158,-1158,-1158}, +{ -599, -808, -788, -788, -788}}, +/* GU.CU..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -859,-1068,-1048,-1048,-1048}, +{ -529, -738, -718, -718, -718}, +{ -859,-1068,-1048,-1048,-1048}, +{ -409, -618, -598, -598, -598}}}, +/* GU.G@..UG */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -769,-1058,-1408,-1408,-1408}, +{ -529, -818,-1168,-1168,-1168}, +{ -709, -998,-1348,-1348,-1348}, +{ -599, -888,-1238,-1238,-1238}}, +/* GU.GC..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -839,-1128,-1478,-1478,-1478}, +{ -529, -818,-1168,-1168,-1168}, +{ -859,-1148,-1498,-1498,-1498}, +{ -489, -778,-1128,-1128,-1128}}, +/* GU.GG..UG */ +{{ DEF, -339, -689, -689, -689}, +{-1009,-1298,-1648,-1648,-1648}, +{ -409, -698,-1048,-1048,-1048}, +{ -969,-1258,-1608,-1608,-1608}, +{ -599, -888,-1238,-1238,-1238}}, +/* GU.GU..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -859,-1148,-1498,-1498,-1498}, +{ -529, -818,-1168,-1168,-1168}, +{ -859,-1148,-1498,-1498,-1498}, +{ -409, -698,-1048,-1048,-1048}}}, +/* GU.U@..UG */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -769,-1048,-1048,-1048,-1048}, +{ -529, -808, -808, -808, -808}, +{ -709, -988, -988, -988, -988}, +{ -599, -878, -878, -878, -878}}, +/* GU.UC..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -839,-1118,-1118,-1118,-1118}, +{ -529, -808, -808, -808, -808}, +{ -859,-1138,-1138,-1138,-1138}, +{ -489, -768, -768, -768, -768}}, +/* GU.UG..UG */ +{{ DEF, -329, -329, -329, -329}, +{-1009,-1288,-1288,-1288,-1288}, +{ -409, -688, -688, -688, -688}, +{ -969,-1248,-1248,-1248,-1248}, +{ -599, -878, -878, -878, -878}}, +/* GU.UU..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -859,-1138,-1138,-1138,-1138}, +{ -529, -808, -808, -808, -808}, +{ -859,-1138,-1138,-1138,-1138}, +{ -409, -688, -688, -688, -688}}}}, +/* GU.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* GU.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GU.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* GU.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* GU.A@..AU */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -479, -858,-1028,-1028,-1028}, +{ -309, -688, -858, -858, -858}, +{ -389, -768, -938, -938, -938}, +{ -379, -758, -928, -928, -928}}, +/* GU.AC..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* GU.AG..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* GU.AU..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}}, +/* GU.C@..AU */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -479, -688, -668, -668, -668}, +{ -309, -518, -498, -498, -498}, +{ -389, -598, -578, -578, -578}, +{ -379, -588, -568, -568, -568}}, +/* GU.CC..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* GU.CG..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* GU.CU..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}}, +/* GU.G@..AU */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -479, -768,-1118,-1118,-1118}, +{ -309, -598, -948, -948, -948}, +{ -389, -678,-1028,-1028,-1028}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GC..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GG..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* GU.GU..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}}, +/* GU.U@..AU */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -479, -758, -758, -758, -758}, +{ -309, -588, -588, -588, -588}, +{ -389, -668, -668, -668, -668}, +{ -379, -658, -658, -658, -658}}, +/* GU.UC..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* GU.UG..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* GU.UU..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}}}, +/* GU.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* GU.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* GU.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* GU.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* GU.A@..UA */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -449, -828, -998, -998, -998}, +{ -479, -858,-1028,-1028,-1028}, +{ -429, -808, -978, -978, -978}, +{ -329, -708, -878, -878, -878}}, +/* GU.AC..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -679,-1058,-1228,-1228,-1228}, +{ -559, -938,-1108,-1108,-1108}, +{ -729,-1108,-1278,-1278,-1278}, +{ -189, -568, -738, -738, -738}}, +/* GU.AG..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -939,-1318,-1488,-1488,-1488}, +{ -249, -628, -798, -798, -798}, +{ -939,-1318,-1488,-1488,-1488}, +{ -329, -708, -878, -878, -878}}, +/* GU.AU..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -639,-1018,-1188,-1188,-1188}, +{ -229, -608, -778, -778, -778}, +{ -729,-1108,-1278,-1278,-1278}, +{ -190, -569, -739, -739, -739}}}, +/* GU.C@..UA */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -449, -658, -638, -638, -638}, +{ -479, -688, -668, -668, -668}, +{ -429, -638, -618, -618, -618}, +{ -329, -538, -518, -518, -518}}, +/* GU.CC..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -679, -888, -868, -868, -868}, +{ -559, -768, -748, -748, -748}, +{ -729, -938, -918, -918, -918}, +{ -189, -398, -378, -378, -378}}, +/* GU.CG..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -939,-1148,-1128,-1128,-1128}, +{ -249, -458, -438, -438, -438}, +{ -939,-1148,-1128,-1128,-1128}, +{ -329, -538, -518, -518, -518}}, +/* GU.CU..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -639, -848, -828, -828, -828}, +{ -229, -438, -418, -418, -418}, +{ -729, -938, -918, -918, -918}, +{ -190, -399, -379, -379, -379}}}, +/* GU.G@..UA */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -449, -738,-1088,-1088,-1088}, +{ -479, -768,-1118,-1118,-1118}, +{ -429, -718,-1068,-1068,-1068}, +{ -329, -618, -968, -968, -968}}, +/* GU.GC..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -679, -968,-1318,-1318,-1318}, +{ -559, -848,-1198,-1198,-1198}, +{ -729,-1018,-1368,-1368,-1368}, +{ -189, -478, -828, -828, -828}}, +/* GU.GG..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -939,-1228,-1578,-1578,-1578}, +{ -249, -538, -888, -888, -888}, +{ -939,-1228,-1578,-1578,-1578}, +{ -329, -618, -968, -968, -968}}, +/* GU.GU..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -639, -928,-1278,-1278,-1278}, +{ -229, -518, -868, -868, -868}, +{ -729,-1018,-1368,-1368,-1368}, +{ -190, -479, -829, -829, -829}}}, +/* GU.U@..UA */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -449, -728, -728, -728, -728}, +{ -479, -758, -758, -758, -758}, +{ -429, -708, -708, -708, -708}, +{ -329, -608, -608, -608, -608}}, +/* GU.UC..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -679, -958, -958, -958, -958}, +{ -559, -838, -838, -838, -838}, +{ -729,-1008,-1008,-1008,-1008}, +{ -189, -468, -468, -468, -468}}, +/* GU.UG..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -939,-1218,-1218,-1218,-1218}, +{ -249, -528, -528, -528, -528}, +{ -939,-1218,-1218,-1218,-1218}, +{ -329, -608, -608, -608, -608}}, +/* GU.UU..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -639, -918, -918, -918, -918}, +{ -229, -508, -508, -508, -508}, +{ -729,-1008,-1008,-1008,-1008}, +{ -190, -469, -469, -469, -469}}}}, +/* GU.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* GU.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* GU.A@.. @ */ +{{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AA.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AC.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AG.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* GU.AU.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}}, +/* GU.C@.. @ */ +{{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CA.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CC.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CG.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* GU.CU.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}}, +/* GU.G@.. @ */ +{{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GA.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GC.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GG.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* GU.GU.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}}, +/* GU.U@.. @ */ +{{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UA.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UC.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UG.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* GU.UU.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}}}}, +{ /* noPair */ {{{{0}}}}, +/* UG.@@..CG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* UG.@C..CG */ +{{ 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* UG.@G..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* UG.@U..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* UG.A@..CG */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..CG */ +{{ DEF, -719, -789, -959, -809}, +{-1079,-1748,-1818,-1988,-1838}, +{ -569,-1238,-1308,-1478,-1328}, +{ -989,-1658,-1728,-1898,-1748}, +{ -859,-1528,-1598,-1768,-1618}}, +/* UG.AC..CG */ +{{ DEF, -719, -789, -959, -809}, +{ -999,-1668,-1738,-1908,-1758}, +{ -499,-1168,-1238,-1408,-1258}, +{ -989,-1658,-1728,-1898,-1748}, +{ -789,-1458,-1528,-1698,-1548}}, +/* UG.AG..CG */ +{{ DEF, -719, -789, -959, -809}, +{-1079,-1748,-1818,-1988,-1838}, +{ -569,-1238,-1308,-1478,-1328}, +{ -989,-1658,-1728,-1898,-1748}, +{ -859,-1528,-1598,-1768,-1618}}, +/* UG.AU..CG */ +{{ DEF, -719, -789, -959, -809}, +{-1079,-1748,-1818,-1988,-1838}, +{ -719,-1388,-1458,-1628,-1478}, +{ -989,-1658,-1728,-1898,-1748}, +{ -909,-1578,-1648,-1818,-1668}}}, +/* UG.C@..CG */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..CG */ +{{ DEF, -479, -479, -359, -479}, +{-1079,-1508,-1508,-1388,-1508}, +{ -569, -998, -998, -878, -998}, +{ -989,-1418,-1418,-1298,-1418}, +{ -859,-1288,-1288,-1168,-1288}}, +/* UG.CC..CG */ +{{ DEF, -479, -479, -359, -479}, +{ -999,-1428,-1428,-1308,-1428}, +{ -499, -928, -928, -808, -928}, +{ -989,-1418,-1418,-1298,-1418}, +{ -789,-1218,-1218,-1098,-1218}}, +/* UG.CG..CG */ +{{ DEF, -479, -479, -359, -479}, +{-1079,-1508,-1508,-1388,-1508}, +{ -569, -998, -998, -878, -998}, +{ -989,-1418,-1418,-1298,-1418}, +{ -859,-1288,-1288,-1168,-1288}}, +/* UG.CU..CG */ +{{ DEF, -479, -479, -359, -479}, +{-1079,-1508,-1508,-1388,-1508}, +{ -719,-1148,-1148,-1028,-1148}, +{ -989,-1418,-1418,-1298,-1418}, +{ -909,-1338,-1338,-1218,-1338}}}, +/* UG.G@..CG */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..CG */ +{{ DEF, -659, -809, -919, -809}, +{-1079,-1688,-1838,-1948,-1838}, +{ -569,-1178,-1328,-1438,-1328}, +{ -989,-1598,-1748,-1858,-1748}, +{ -859,-1468,-1618,-1728,-1618}}, +/* UG.GC..CG */ +{{ DEF, -659, -809, -919, -809}, +{ -999,-1608,-1758,-1868,-1758}, +{ -499,-1108,-1258,-1368,-1258}, +{ -989,-1598,-1748,-1858,-1748}, +{ -789,-1398,-1548,-1658,-1548}}, +/* UG.GG..CG */ +{{ DEF, -659, -809, -919, -809}, +{-1079,-1688,-1838,-1948,-1838}, +{ -569,-1178,-1328,-1438,-1328}, +{ -989,-1598,-1748,-1858,-1748}, +{ -859,-1468,-1618,-1728,-1618}}, +/* UG.GU..CG */ +{{ DEF, -659, -809, -919, -809}, +{-1079,-1688,-1838,-1948,-1838}, +{ -719,-1328,-1478,-1588,-1478}, +{ -989,-1598,-1748,-1858,-1748}, +{ -909,-1518,-1668,-1778,-1668}}}, +/* UG.U@..CG */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..CG */ +{{ DEF, -549, -439, -549, -359}, +{-1079,-1578,-1468,-1578,-1388}, +{ -569,-1068, -958,-1068, -878}, +{ -989,-1488,-1378,-1488,-1298}, +{ -859,-1358,-1248,-1358,-1168}}, +/* UG.UC..CG */ +{{ DEF, -549, -439, -549, -359}, +{ -999,-1498,-1388,-1498,-1308}, +{ -499, -998, -888, -998, -808}, +{ -989,-1488,-1378,-1488,-1298}, +{ -789,-1288,-1178,-1288,-1098}}, +/* UG.UG..CG */ +{{ DEF, -549, -439, -549, -359}, +{-1079,-1578,-1468,-1578,-1388}, +{ -569,-1068, -958,-1068, -878}, +{ -989,-1488,-1378,-1488,-1298}, +{ -859,-1358,-1248,-1358,-1168}}, +/* UG.UU..CG */ +{{ DEF, -549, -439, -549, -359}, +{-1079,-1578,-1468,-1578,-1388}, +{ -719,-1218,-1108,-1218,-1028}, +{ -989,-1488,-1378,-1488,-1298}, +{ -909,-1408,-1298,-1408,-1218}}}}, +/* UG.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* UG.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* UG.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* UG.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* UG.A@..GC */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..GC */ +{{ DEF, -719, -789, -959, -809}, +{ -569,-1238,-1308,-1478,-1328}, +{ -769,-1438,-1508,-1678,-1528}, +{ -759,-1428,-1498,-1668,-1518}, +{ -549,-1218,-1288,-1458,-1308}}, +/* UG.AC..GC */ +{{ DEF, -719, -789, -959, -809}, +{ -929,-1598,-1668,-1838,-1688}, +{ -359,-1028,-1098,-1268,-1118}, +{ -789,-1458,-1528,-1698,-1548}, +{ -549,-1218,-1288,-1458,-1308}}, +/* UG.AG..GC */ +{{ DEF, -719, -789, -959, -809}, +{ -609,-1278,-1348,-1518,-1368}, +{ -359,-1028,-1098,-1268,-1118}, +{ -669,-1338,-1408,-1578,-1428}, +{ -549,-1218,-1288,-1458,-1308}}, +/* UG.AU..GC */ +{{ DEF, -719, -789, -959, -809}, +{ -929,-1598,-1668,-1838,-1688}, +{ -439,-1108,-1178,-1348,-1198}, +{ -789,-1458,-1528,-1698,-1548}, +{ -619,-1288,-1358,-1528,-1378}}}, +/* UG.C@..GC */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..GC */ +{{ DEF, -479, -479, -359, -479}, +{ -569, -998, -998, -878, -998}, +{ -769,-1198,-1198,-1078,-1198}, +{ -759,-1188,-1188,-1068,-1188}, +{ -549, -978, -978, -858, -978}}, +/* UG.CC..GC */ +{{ DEF, -479, -479, -359, -479}, +{ -929,-1358,-1358,-1238,-1358}, +{ -359, -788, -788, -668, -788}, +{ -789,-1218,-1218,-1098,-1218}, +{ -549, -978, -978, -858, -978}}, +/* UG.CG..GC */ +{{ DEF, -479, -479, -359, -479}, +{ -609,-1038,-1038, -918,-1038}, +{ -359, -788, -788, -668, -788}, +{ -669,-1098,-1098, -978,-1098}, +{ -549, -978, -978, -858, -978}}, +/* UG.CU..GC */ +{{ DEF, -479, -479, -359, -479}, +{ -929,-1358,-1358,-1238,-1358}, +{ -439, -868, -868, -748, -868}, +{ -789,-1218,-1218,-1098,-1218}, +{ -619,-1048,-1048, -928,-1048}}}, +/* UG.G@..GC */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..GC */ +{{ DEF, -659, -809, -919, -809}, +{ -569,-1178,-1328,-1438,-1328}, +{ -769,-1378,-1528,-1638,-1528}, +{ -759,-1368,-1518,-1628,-1518}, +{ -549,-1158,-1308,-1418,-1308}}, +/* UG.GC..GC */ +{{ DEF, -659, -809, -919, -809}, +{ -929,-1538,-1688,-1798,-1688}, +{ -359, -968,-1118,-1228,-1118}, +{ -789,-1398,-1548,-1658,-1548}, +{ -549,-1158,-1308,-1418,-1308}}, +/* UG.GG..GC */ +{{ DEF, -659, -809, -919, -809}, +{ -609,-1218,-1368,-1478,-1368}, +{ -359, -968,-1118,-1228,-1118}, +{ -669,-1278,-1428,-1538,-1428}, +{ -549,-1158,-1308,-1418,-1308}}, +/* UG.GU..GC */ +{{ DEF, -659, -809, -919, -809}, +{ -929,-1538,-1688,-1798,-1688}, +{ -439,-1048,-1198,-1308,-1198}, +{ -789,-1398,-1548,-1658,-1548}, +{ -619,-1228,-1378,-1488,-1378}}}, +/* UG.U@..GC */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..GC */ +{{ DEF, -549, -439, -549, -359}, +{ -569,-1068, -958,-1068, -878}, +{ -769,-1268,-1158,-1268,-1078}, +{ -759,-1258,-1148,-1258,-1068}, +{ -549,-1048, -938,-1048, -858}}, +/* UG.UC..GC */ +{{ DEF, -549, -439, -549, -359}, +{ -929,-1428,-1318,-1428,-1238}, +{ -359, -858, -748, -858, -668}, +{ -789,-1288,-1178,-1288,-1098}, +{ -549,-1048, -938,-1048, -858}}, +/* UG.UG..GC */ +{{ DEF, -549, -439, -549, -359}, +{ -609,-1108, -998,-1108, -918}, +{ -359, -858, -748, -858, -668}, +{ -669,-1168,-1058,-1168, -978}, +{ -549,-1048, -938,-1048, -858}}, +/* UG.UU..GC */ +{{ DEF, -549, -439, -549, -359}, +{ -929,-1428,-1318,-1428,-1238}, +{ -439, -938, -828, -938, -748}, +{ -789,-1288,-1178,-1288,-1098}, +{ -619,-1118,-1008,-1118, -928}}}}, +/* UG.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* UG.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UG.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UG.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* UG.A@..GU */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..GU */ +{{ DEF, -719, -789, -959, -809}, +{ -479,-1148,-1218,-1388,-1238}, +{ -309, -978,-1048,-1218,-1068}, +{ -389,-1058,-1128,-1298,-1148}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AC..GU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AG..GU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AU..GU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}}, +/* UG.C@..GU */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..GU */ +{{ DEF, -479, -479, -359, -479}, +{ -479, -908, -908, -788, -908}, +{ -309, -738, -738, -618, -738}, +{ -389, -818, -818, -698, -818}, +{ -379, -808, -808, -688, -808}}, +/* UG.CC..GU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}, +/* UG.CG..GU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}, +/* UG.CU..GU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}}, +/* UG.G@..GU */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..GU */ +{{ DEF, -659, -809, -919, -809}, +{ -479,-1088,-1238,-1348,-1238}, +{ -309, -918,-1068,-1178,-1068}, +{ -389, -998,-1148,-1258,-1148}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GC..GU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GG..GU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GU..GU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}}, +/* UG.U@..GU */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..GU */ +{{ DEF, -549, -439, -549, -359}, +{ -479, -978, -868, -978, -788}, +{ -309, -808, -698, -808, -618}, +{ -389, -888, -778, -888, -698}, +{ -379, -878, -768, -878, -688}}, +/* UG.UC..GU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}, +/* UG.UG..GU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}, +/* UG.UU..GU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}}}, +/* UG.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* UG.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* UG.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* UG.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* UG.A@..UG */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..UG */ +{{ DEF, -719, -789, -959, -809}, +{ -769,-1438,-1508,-1678,-1528}, +{ -529,-1198,-1268,-1438,-1288}, +{ -709,-1378,-1448,-1618,-1468}, +{ -599,-1268,-1338,-1508,-1358}}, +/* UG.AC..UG */ +{{ DEF, -719, -789, -959, -809}, +{ -839,-1508,-1578,-1748,-1598}, +{ -529,-1198,-1268,-1438,-1288}, +{ -859,-1528,-1598,-1768,-1618}, +{ -489,-1158,-1228,-1398,-1248}}, +/* UG.AG..UG */ +{{ DEF, -719, -789, -959, -809}, +{-1009,-1678,-1748,-1918,-1768}, +{ -409,-1078,-1148,-1318,-1168}, +{ -969,-1638,-1708,-1878,-1728}, +{ -599,-1268,-1338,-1508,-1358}}, +/* UG.AU..UG */ +{{ DEF, -719, -789, -959, -809}, +{ -859,-1528,-1598,-1768,-1618}, +{ -529,-1198,-1268,-1438,-1288}, +{ -859,-1528,-1598,-1768,-1618}, +{ -409,-1078,-1148,-1318,-1168}}}, +/* UG.C@..UG */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..UG */ +{{ DEF, -479, -479, -359, -479}, +{ -769,-1198,-1198,-1078,-1198}, +{ -529, -958, -958, -838, -958}, +{ -709,-1138,-1138,-1018,-1138}, +{ -599,-1028,-1028, -908,-1028}}, +/* UG.CC..UG */ +{{ DEF, -479, -479, -359, -479}, +{ -839,-1268,-1268,-1148,-1268}, +{ -529, -958, -958, -838, -958}, +{ -859,-1288,-1288,-1168,-1288}, +{ -489, -918, -918, -798, -918}}, +/* UG.CG..UG */ +{{ DEF, -479, -479, -359, -479}, +{-1009,-1438,-1438,-1318,-1438}, +{ -409, -838, -838, -718, -838}, +{ -969,-1398,-1398,-1278,-1398}, +{ -599,-1028,-1028, -908,-1028}}, +/* UG.CU..UG */ +{{ DEF, -479, -479, -359, -479}, +{ -859,-1288,-1288,-1168,-1288}, +{ -529, -958, -958, -838, -958}, +{ -859,-1288,-1288,-1168,-1288}, +{ -409, -838, -838, -718, -838}}}, +/* UG.G@..UG */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..UG */ +{{ DEF, -659, -809, -919, -809}, +{ -769,-1378,-1528,-1638,-1528}, +{ -529,-1138,-1288,-1398,-1288}, +{ -709,-1318,-1468,-1578,-1468}, +{ -599,-1208,-1358,-1468,-1358}}, +/* UG.GC..UG */ +{{ DEF, -659, -809, -919, -809}, +{ -839,-1448,-1598,-1708,-1598}, +{ -529,-1138,-1288,-1398,-1288}, +{ -859,-1468,-1618,-1728,-1618}, +{ -489,-1098,-1248,-1358,-1248}}, +/* UG.GG..UG */ +{{ DEF, -659, -809, -919, -809}, +{-1009,-1618,-1768,-1878,-1768}, +{ -409,-1018,-1168,-1278,-1168}, +{ -969,-1578,-1728,-1838,-1728}, +{ -599,-1208,-1358,-1468,-1358}}, +/* UG.GU..UG */ +{{ DEF, -659, -809, -919, -809}, +{ -859,-1468,-1618,-1728,-1618}, +{ -529,-1138,-1288,-1398,-1288}, +{ -859,-1468,-1618,-1728,-1618}, +{ -409,-1018,-1168,-1278,-1168}}}, +/* UG.U@..UG */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..UG */ +{{ DEF, -549, -439, -549, -359}, +{ -769,-1268,-1158,-1268,-1078}, +{ -529,-1028, -918,-1028, -838}, +{ -709,-1208,-1098,-1208,-1018}, +{ -599,-1098, -988,-1098, -908}}, +/* UG.UC..UG */ +{{ DEF, -549, -439, -549, -359}, +{ -839,-1338,-1228,-1338,-1148}, +{ -529,-1028, -918,-1028, -838}, +{ -859,-1358,-1248,-1358,-1168}, +{ -489, -988, -878, -988, -798}}, +/* UG.UG..UG */ +{{ DEF, -549, -439, -549, -359}, +{-1009,-1508,-1398,-1508,-1318}, +{ -409, -908, -798, -908, -718}, +{ -969,-1468,-1358,-1468,-1278}, +{ -599,-1098, -988,-1098, -908}}, +/* UG.UU..UG */ +{{ DEF, -549, -439, -549, -359}, +{ -859,-1358,-1248,-1358,-1168}, +{ -529,-1028, -918,-1028, -838}, +{ -859,-1358,-1248,-1358,-1168}, +{ -409, -908, -798, -908, -718}}}}, +/* UG.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* UG.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UG.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UG.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* UG.A@..AU */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..AU */ +{{ DEF, -719, -789, -959, -809}, +{ -479,-1148,-1218,-1388,-1238}, +{ -309, -978,-1048,-1218,-1068}, +{ -389,-1058,-1128,-1298,-1148}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AC..AU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AG..AU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}, +/* UG.AU..AU */ +{{ DEF, -719, -789, -959, -809}, +{ -649,-1318,-1388,-1558,-1408}, +{ -289, -958,-1028,-1198,-1048}, +{ -739,-1408,-1478,-1648,-1498}, +{ -379,-1048,-1118,-1288,-1138}}}, +/* UG.C@..AU */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..AU */ +{{ DEF, -479, -479, -359, -479}, +{ -479, -908, -908, -788, -908}, +{ -309, -738, -738, -618, -738}, +{ -389, -818, -818, -698, -818}, +{ -379, -808, -808, -688, -808}}, +/* UG.CC..AU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}, +/* UG.CG..AU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}, +/* UG.CU..AU */ +{{ DEF, -479, -479, -359, -479}, +{ -649,-1078,-1078, -958,-1078}, +{ -289, -718, -718, -598, -718}, +{ -739,-1168,-1168,-1048,-1168}, +{ -379, -808, -808, -688, -808}}}, +/* UG.G@..AU */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..AU */ +{{ DEF, -659, -809, -919, -809}, +{ -479,-1088,-1238,-1348,-1238}, +{ -309, -918,-1068,-1178,-1068}, +{ -389, -998,-1148,-1258,-1148}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GC..AU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GG..AU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}, +/* UG.GU..AU */ +{{ DEF, -659, -809, -919, -809}, +{ -649,-1258,-1408,-1518,-1408}, +{ -289, -898,-1048,-1158,-1048}, +{ -739,-1348,-1498,-1608,-1498}, +{ -379, -988,-1138,-1248,-1138}}}, +/* UG.U@..AU */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..AU */ +{{ DEF, -549, -439, -549, -359}, +{ -479, -978, -868, -978, -788}, +{ -309, -808, -698, -808, -618}, +{ -389, -888, -778, -888, -698}, +{ -379, -878, -768, -878, -688}}, +/* UG.UC..AU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}, +/* UG.UG..AU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}, +/* UG.UU..AU */ +{{ DEF, -549, -439, -549, -359}, +{ -649,-1148,-1038,-1148, -958}, +{ -289, -788, -678, -788, -598}, +{ -739,-1238,-1128,-1238,-1048}, +{ -379, -878, -768, -878, -688}}}}, +/* UG.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* UG.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* UG.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* UG.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* UG.A@..UA */ +{{{ DEF, -719, -789, -959, -809}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA..UA */ +{{ DEF, -719, -789, -959, -809}, +{ -449,-1118,-1188,-1358,-1208}, +{ -479,-1148,-1218,-1388,-1238}, +{ -429,-1098,-1168,-1338,-1188}, +{ -329, -998,-1068,-1238,-1088}}, +/* UG.AC..UA */ +{{ DEF, -719, -789, -959, -809}, +{ -679,-1348,-1418,-1588,-1438}, +{ -559,-1228,-1298,-1468,-1318}, +{ -729,-1398,-1468,-1638,-1488}, +{ -189, -858, -928,-1098, -948}}, +/* UG.AG..UA */ +{{ DEF, -719, -789, -959, -809}, +{ -939,-1608,-1678,-1848,-1698}, +{ -249, -918, -988,-1158,-1008}, +{ -939,-1608,-1678,-1848,-1698}, +{ -329, -998,-1068,-1238,-1088}}, +/* UG.AU..UA */ +{{ DEF, -719, -789, -959, -809}, +{ -639,-1308,-1378,-1548,-1398}, +{ -229, -898, -968,-1138, -988}, +{ -729,-1398,-1468,-1638,-1488}, +{ -190, -859, -929,-1099, -949}}}, +/* UG.C@..UA */ +{{{ DEF, -479, -479, -359, -479}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA..UA */ +{{ DEF, -479, -479, -359, -479}, +{ -449, -878, -878, -758, -878}, +{ -479, -908, -908, -788, -908}, +{ -429, -858, -858, -738, -858}, +{ -329, -758, -758, -638, -758}}, +/* UG.CC..UA */ +{{ DEF, -479, -479, -359, -479}, +{ -679,-1108,-1108, -988,-1108}, +{ -559, -988, -988, -868, -988}, +{ -729,-1158,-1158,-1038,-1158}, +{ -189, -618, -618, -498, -618}}, +/* UG.CG..UA */ +{{ DEF, -479, -479, -359, -479}, +{ -939,-1368,-1368,-1248,-1368}, +{ -249, -678, -678, -558, -678}, +{ -939,-1368,-1368,-1248,-1368}, +{ -329, -758, -758, -638, -758}}, +/* UG.CU..UA */ +{{ DEF, -479, -479, -359, -479}, +{ -639,-1068,-1068, -948,-1068}, +{ -229, -658, -658, -538, -658}, +{ -729,-1158,-1158,-1038,-1158}, +{ -190, -619, -619, -499, -619}}}, +/* UG.G@..UA */ +{{{ DEF, -659, -809, -919, -809}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA..UA */ +{{ DEF, -659, -809, -919, -809}, +{ -449,-1058,-1208,-1318,-1208}, +{ -479,-1088,-1238,-1348,-1238}, +{ -429,-1038,-1188,-1298,-1188}, +{ -329, -938,-1088,-1198,-1088}}, +/* UG.GC..UA */ +{{ DEF, -659, -809, -919, -809}, +{ -679,-1288,-1438,-1548,-1438}, +{ -559,-1168,-1318,-1428,-1318}, +{ -729,-1338,-1488,-1598,-1488}, +{ -189, -798, -948,-1058, -948}}, +/* UG.GG..UA */ +{{ DEF, -659, -809, -919, -809}, +{ -939,-1548,-1698,-1808,-1698}, +{ -249, -858,-1008,-1118,-1008}, +{ -939,-1548,-1698,-1808,-1698}, +{ -329, -938,-1088,-1198,-1088}}, +/* UG.GU..UA */ +{{ DEF, -659, -809, -919, -809}, +{ -639,-1248,-1398,-1508,-1398}, +{ -229, -838, -988,-1098, -988}, +{ -729,-1338,-1488,-1598,-1488}, +{ -190, -799, -949,-1059, -949}}}, +/* UG.U@..UA */ +{{{ DEF, -549, -439, -549, -359}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA..UA */ +{{ DEF, -549, -439, -549, -359}, +{ -449, -948, -838, -948, -758}, +{ -479, -978, -868, -978, -788}, +{ -429, -928, -818, -928, -738}, +{ -329, -828, -718, -828, -638}}, +/* UG.UC..UA */ +{{ DEF, -549, -439, -549, -359}, +{ -679,-1178,-1068,-1178, -988}, +{ -559,-1058, -948,-1058, -868}, +{ -729,-1228,-1118,-1228,-1038}, +{ -189, -688, -578, -688, -498}}, +/* UG.UG..UA */ +{{ DEF, -549, -439, -549, -359}, +{ -939,-1438,-1328,-1438,-1248}, +{ -249, -748, -638, -748, -558}, +{ -939,-1438,-1328,-1438,-1248}, +{ -329, -828, -718, -828, -638}}, +/* UG.UU..UA */ +{{ DEF, -549, -439, -549, -359}, +{ -639,-1138,-1028,-1138, -948}, +{ -229, -728, -618, -728, -538}, +{ -729,-1228,-1118,-1228,-1038}, +{ -190, -689, -579, -689, -499}}}}, +/* UG.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UG.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* UG.A@.. @ */ +{{{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AA.. @ */ +{{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AC.. @ */ +{{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AG.. @ */ +{{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}, +/* UG.AU.. @ */ +{{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}, +{ -100, -769, -839,-1009, -859}}}, +/* UG.C@.. @ */ +{{{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CA.. @ */ +{{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CC.. @ */ +{{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CG.. @ */ +{{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}, +/* UG.CU.. @ */ +{{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}, +{ -100, -529, -529, -409, -529}}}, +/* UG.G@.. @ */ +{{{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GA.. @ */ +{{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GC.. @ */ +{{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GG.. @ */ +{{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}, +/* UG.GU.. @ */ +{{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}, +{ -100, -709, -859, -969, -859}}}, +/* UG.U@.. @ */ +{{{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UA.. @ */ +{{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UC.. @ */ +{{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UG.. @ */ +{{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}, +/* UG.UU.. @ */ +{{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}, +{ -100, -599, -489, -599, -409}}}}}, +{ /* noPair */ {{{{0}}}}, +/* AU.@@..CG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* AU.@C..CG */ +{{ 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* AU.@G..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* AU.@U..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* AU.A@..CG */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -569, -948,-1118,-1118,-1118}, +{ -989,-1368,-1538,-1538,-1538}, +{ -859,-1238,-1408,-1408,-1408}}, +/* AU.AC..CG */ +{{ DEF, -429, -599, -599, -599}, +{ -999,-1378,-1548,-1548,-1548}, +{ -499, -878,-1048,-1048,-1048}, +{ -989,-1368,-1538,-1538,-1538}, +{ -789,-1168,-1338,-1338,-1338}}, +/* AU.AG..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -569, -948,-1118,-1118,-1118}, +{ -989,-1368,-1538,-1538,-1538}, +{ -859,-1238,-1408,-1408,-1408}}, +/* AU.AU..CG */ +{{ DEF, -429, -599, -599, -599}, +{-1079,-1458,-1628,-1628,-1628}, +{ -719,-1098,-1268,-1268,-1268}, +{ -989,-1368,-1538,-1538,-1538}, +{ -909,-1288,-1458,-1458,-1458}}}, +/* AU.C@..CG */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -569, -778, -758, -758, -758}, +{ -989,-1198,-1178,-1178,-1178}, +{ -859,-1068,-1048,-1048,-1048}}, +/* AU.CC..CG */ +{{ DEF, -259, -239, -239, -239}, +{ -999,-1208,-1188,-1188,-1188}, +{ -499, -708, -688, -688, -688}, +{ -989,-1198,-1178,-1178,-1178}, +{ -789, -998, -978, -978, -978}}, +/* AU.CG..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -569, -778, -758, -758, -758}, +{ -989,-1198,-1178,-1178,-1178}, +{ -859,-1068,-1048,-1048,-1048}}, +/* AU.CU..CG */ +{{ DEF, -259, -239, -239, -239}, +{-1079,-1288,-1268,-1268,-1268}, +{ -719, -928, -908, -908, -908}, +{ -989,-1198,-1178,-1178,-1178}, +{ -909,-1118,-1098,-1098,-1098}}}, +/* AU.G@..CG */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -569, -858,-1208,-1208,-1208}, +{ -989,-1278,-1628,-1628,-1628}, +{ -859,-1148,-1498,-1498,-1498}}, +/* AU.GC..CG */ +{{ DEF, -339, -689, -689, -689}, +{ -999,-1288,-1638,-1638,-1638}, +{ -499, -788,-1138,-1138,-1138}, +{ -989,-1278,-1628,-1628,-1628}, +{ -789,-1078,-1428,-1428,-1428}}, +/* AU.GG..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -569, -858,-1208,-1208,-1208}, +{ -989,-1278,-1628,-1628,-1628}, +{ -859,-1148,-1498,-1498,-1498}}, +/* AU.GU..CG */ +{{ DEF, -339, -689, -689, -689}, +{-1079,-1368,-1718,-1718,-1718}, +{ -719,-1008,-1358,-1358,-1358}, +{ -989,-1278,-1628,-1628,-1628}, +{ -909,-1198,-1548,-1548,-1548}}}, +/* AU.U@..CG */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -569, -848, -848, -848, -848}, +{ -989,-1268,-1268,-1268,-1268}, +{ -859,-1138,-1138,-1138,-1138}}, +/* AU.UC..CG */ +{{ DEF, -329, -329, -329, -329}, +{ -999,-1278,-1278,-1278,-1278}, +{ -499, -778, -778, -778, -778}, +{ -989,-1268,-1268,-1268,-1268}, +{ -789,-1068,-1068,-1068,-1068}}, +/* AU.UG..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -569, -848, -848, -848, -848}, +{ -989,-1268,-1268,-1268,-1268}, +{ -859,-1138,-1138,-1138,-1138}}, +/* AU.UU..CG */ +{{ DEF, -329, -329, -329, -329}, +{-1079,-1358,-1358,-1358,-1358}, +{ -719, -998, -998, -998, -998}, +{ -989,-1268,-1268,-1268,-1268}, +{ -909,-1188,-1188,-1188,-1188}}}}, +/* AU.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* AU.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* AU.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* AU.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* AU.A@..GC */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -569, -948,-1118,-1118,-1118}, +{ -769,-1148,-1318,-1318,-1318}, +{ -759,-1138,-1308,-1308,-1308}, +{ -549, -928,-1098,-1098,-1098}}, +/* AU.AC..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -929,-1308,-1478,-1478,-1478}, +{ -359, -738, -908, -908, -908}, +{ -789,-1168,-1338,-1338,-1338}, +{ -549, -928,-1098,-1098,-1098}}, +/* AU.AG..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -609, -988,-1158,-1158,-1158}, +{ -359, -738, -908, -908, -908}, +{ -669,-1048,-1218,-1218,-1218}, +{ -549, -928,-1098,-1098,-1098}}, +/* AU.AU..GC */ +{{ DEF, -429, -599, -599, -599}, +{ -929,-1308,-1478,-1478,-1478}, +{ -439, -818, -988, -988, -988}, +{ -789,-1168,-1338,-1338,-1338}, +{ -619, -998,-1168,-1168,-1168}}}, +/* AU.C@..GC */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -569, -778, -758, -758, -758}, +{ -769, -978, -958, -958, -958}, +{ -759, -968, -948, -948, -948}, +{ -549, -758, -738, -738, -738}}, +/* AU.CC..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -929,-1138,-1118,-1118,-1118}, +{ -359, -568, -548, -548, -548}, +{ -789, -998, -978, -978, -978}, +{ -549, -758, -738, -738, -738}}, +/* AU.CG..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -609, -818, -798, -798, -798}, +{ -359, -568, -548, -548, -548}, +{ -669, -878, -858, -858, -858}, +{ -549, -758, -738, -738, -738}}, +/* AU.CU..GC */ +{{ DEF, -259, -239, -239, -239}, +{ -929,-1138,-1118,-1118,-1118}, +{ -439, -648, -628, -628, -628}, +{ -789, -998, -978, -978, -978}, +{ -619, -828, -808, -808, -808}}}, +/* AU.G@..GC */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -569, -858,-1208,-1208,-1208}, +{ -769,-1058,-1408,-1408,-1408}, +{ -759,-1048,-1398,-1398,-1398}, +{ -549, -838,-1188,-1188,-1188}}, +/* AU.GC..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -929,-1218,-1568,-1568,-1568}, +{ -359, -648, -998, -998, -998}, +{ -789,-1078,-1428,-1428,-1428}, +{ -549, -838,-1188,-1188,-1188}}, +/* AU.GG..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -609, -898,-1248,-1248,-1248}, +{ -359, -648, -998, -998, -998}, +{ -669, -958,-1308,-1308,-1308}, +{ -549, -838,-1188,-1188,-1188}}, +/* AU.GU..GC */ +{{ DEF, -339, -689, -689, -689}, +{ -929,-1218,-1568,-1568,-1568}, +{ -439, -728,-1078,-1078,-1078}, +{ -789,-1078,-1428,-1428,-1428}, +{ -619, -908,-1258,-1258,-1258}}}, +/* AU.U@..GC */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -569, -848, -848, -848, -848}, +{ -769,-1048,-1048,-1048,-1048}, +{ -759,-1038,-1038,-1038,-1038}, +{ -549, -828, -828, -828, -828}}, +/* AU.UC..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -929,-1208,-1208,-1208,-1208}, +{ -359, -638, -638, -638, -638}, +{ -789,-1068,-1068,-1068,-1068}, +{ -549, -828, -828, -828, -828}}, +/* AU.UG..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -609, -888, -888, -888, -888}, +{ -359, -638, -638, -638, -638}, +{ -669, -948, -948, -948, -948}, +{ -549, -828, -828, -828, -828}}, +/* AU.UU..GC */ +{{ DEF, -329, -329, -329, -329}, +{ -929,-1208,-1208,-1208,-1208}, +{ -439, -718, -718, -718, -718}, +{ -789,-1068,-1068,-1068,-1068}, +{ -619, -898, -898, -898, -898}}}}, +/* AU.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* AU.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* AU.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* AU.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* AU.A@..GU */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -479, -858,-1028,-1028,-1028}, +{ -309, -688, -858, -858, -858}, +{ -389, -768, -938, -938, -938}, +{ -379, -758, -928, -928, -928}}, +/* AU.AC..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* AU.AG..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* AU.AU..GU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}}, +/* AU.C@..GU */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -479, -688, -668, -668, -668}, +{ -309, -518, -498, -498, -498}, +{ -389, -598, -578, -578, -578}, +{ -379, -588, -568, -568, -568}}, +/* AU.CC..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* AU.CG..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* AU.CU..GU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}}, +/* AU.G@..GU */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -479, -768,-1118,-1118,-1118}, +{ -309, -598, -948, -948, -948}, +{ -389, -678,-1028,-1028,-1028}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GC..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GG..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GU..GU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}}, +/* AU.U@..GU */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -479, -758, -758, -758, -758}, +{ -309, -588, -588, -588, -588}, +{ -389, -668, -668, -668, -668}, +{ -379, -658, -658, -658, -658}}, +/* AU.UC..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* AU.UG..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* AU.UU..GU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}}}, +/* AU.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* AU.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* AU.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* AU.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* AU.A@..UG */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -769,-1148,-1318,-1318,-1318}, +{ -529, -908,-1078,-1078,-1078}, +{ -709,-1088,-1258,-1258,-1258}, +{ -599, -978,-1148,-1148,-1148}}, +/* AU.AC..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -839,-1218,-1388,-1388,-1388}, +{ -529, -908,-1078,-1078,-1078}, +{ -859,-1238,-1408,-1408,-1408}, +{ -489, -868,-1038,-1038,-1038}}, +/* AU.AG..UG */ +{{ DEF, -429, -599, -599, -599}, +{-1009,-1388,-1558,-1558,-1558}, +{ -409, -788, -958, -958, -958}, +{ -969,-1348,-1518,-1518,-1518}, +{ -599, -978,-1148,-1148,-1148}}, +/* AU.AU..UG */ +{{ DEF, -429, -599, -599, -599}, +{ -859,-1238,-1408,-1408,-1408}, +{ -529, -908,-1078,-1078,-1078}, +{ -859,-1238,-1408,-1408,-1408}, +{ -409, -788, -958, -958, -958}}}, +/* AU.C@..UG */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -769, -978, -958, -958, -958}, +{ -529, -738, -718, -718, -718}, +{ -709, -918, -898, -898, -898}, +{ -599, -808, -788, -788, -788}}, +/* AU.CC..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -839,-1048,-1028,-1028,-1028}, +{ -529, -738, -718, -718, -718}, +{ -859,-1068,-1048,-1048,-1048}, +{ -489, -698, -678, -678, -678}}, +/* AU.CG..UG */ +{{ DEF, -259, -239, -239, -239}, +{-1009,-1218,-1198,-1198,-1198}, +{ -409, -618, -598, -598, -598}, +{ -969,-1178,-1158,-1158,-1158}, +{ -599, -808, -788, -788, -788}}, +/* AU.CU..UG */ +{{ DEF, -259, -239, -239, -239}, +{ -859,-1068,-1048,-1048,-1048}, +{ -529, -738, -718, -718, -718}, +{ -859,-1068,-1048,-1048,-1048}, +{ -409, -618, -598, -598, -598}}}, +/* AU.G@..UG */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -769,-1058,-1408,-1408,-1408}, +{ -529, -818,-1168,-1168,-1168}, +{ -709, -998,-1348,-1348,-1348}, +{ -599, -888,-1238,-1238,-1238}}, +/* AU.GC..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -839,-1128,-1478,-1478,-1478}, +{ -529, -818,-1168,-1168,-1168}, +{ -859,-1148,-1498,-1498,-1498}, +{ -489, -778,-1128,-1128,-1128}}, +/* AU.GG..UG */ +{{ DEF, -339, -689, -689, -689}, +{-1009,-1298,-1648,-1648,-1648}, +{ -409, -698,-1048,-1048,-1048}, +{ -969,-1258,-1608,-1608,-1608}, +{ -599, -888,-1238,-1238,-1238}}, +/* AU.GU..UG */ +{{ DEF, -339, -689, -689, -689}, +{ -859,-1148,-1498,-1498,-1498}, +{ -529, -818,-1168,-1168,-1168}, +{ -859,-1148,-1498,-1498,-1498}, +{ -409, -698,-1048,-1048,-1048}}}, +/* AU.U@..UG */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -769,-1048,-1048,-1048,-1048}, +{ -529, -808, -808, -808, -808}, +{ -709, -988, -988, -988, -988}, +{ -599, -878, -878, -878, -878}}, +/* AU.UC..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -839,-1118,-1118,-1118,-1118}, +{ -529, -808, -808, -808, -808}, +{ -859,-1138,-1138,-1138,-1138}, +{ -489, -768, -768, -768, -768}}, +/* AU.UG..UG */ +{{ DEF, -329, -329, -329, -329}, +{-1009,-1288,-1288,-1288,-1288}, +{ -409, -688, -688, -688, -688}, +{ -969,-1248,-1248,-1248,-1248}, +{ -599, -878, -878, -878, -878}}, +/* AU.UU..UG */ +{{ DEF, -329, -329, -329, -329}, +{ -859,-1138,-1138,-1138,-1138}, +{ -529, -808, -808, -808, -808}, +{ -859,-1138,-1138,-1138,-1138}, +{ -409, -688, -688, -688, -688}}}}, +/* AU.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* AU.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* AU.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* AU.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* AU.A@..AU */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -479, -858,-1028,-1028,-1028}, +{ -309, -688, -858, -858, -858}, +{ -389, -768, -938, -938, -938}, +{ -379, -758, -928, -928, -928}}, +/* AU.AC..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* AU.AG..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}, +/* AU.AU..AU */ +{{ DEF, -429, -599, -599, -599}, +{ -649,-1028,-1198,-1198,-1198}, +{ -289, -668, -838, -838, -838}, +{ -739,-1118,-1288,-1288,-1288}, +{ -379, -758, -928, -928, -928}}}, +/* AU.C@..AU */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -479, -688, -668, -668, -668}, +{ -309, -518, -498, -498, -498}, +{ -389, -598, -578, -578, -578}, +{ -379, -588, -568, -568, -568}}, +/* AU.CC..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* AU.CG..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}, +/* AU.CU..AU */ +{{ DEF, -259, -239, -239, -239}, +{ -649, -858, -838, -838, -838}, +{ -289, -498, -478, -478, -478}, +{ -739, -948, -928, -928, -928}, +{ -379, -588, -568, -568, -568}}}, +/* AU.G@..AU */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -479, -768,-1118,-1118,-1118}, +{ -309, -598, -948, -948, -948}, +{ -389, -678,-1028,-1028,-1028}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GC..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GG..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}, +/* AU.GU..AU */ +{{ DEF, -339, -689, -689, -689}, +{ -649, -938,-1288,-1288,-1288}, +{ -289, -578, -928, -928, -928}, +{ -739,-1028,-1378,-1378,-1378}, +{ -379, -668,-1018,-1018,-1018}}}, +/* AU.U@..AU */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -479, -758, -758, -758, -758}, +{ -309, -588, -588, -588, -588}, +{ -389, -668, -668, -668, -668}, +{ -379, -658, -658, -658, -658}}, +/* AU.UC..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* AU.UG..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}, +/* AU.UU..AU */ +{{ DEF, -329, -329, -329, -329}, +{ -649, -928, -928, -928, -928}, +{ -289, -568, -568, -568, -568}, +{ -739,-1018,-1018,-1018,-1018}, +{ -379, -658, -658, -658, -658}}}}, +/* AU.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* AU.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* AU.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* AU.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* AU.A@..UA */ +{{{ DEF, -429, -599, -599, -599}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -449, -828, -998, -998, -998}, +{ -479, -858,-1028,-1028,-1028}, +{ -429, -808, -978, -978, -978}, +{ -329, -708, -878, -878, -878}}, +/* AU.AC..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -679,-1058,-1228,-1228,-1228}, +{ -559, -938,-1108,-1108,-1108}, +{ -729,-1108,-1278,-1278,-1278}, +{ -189, -568, -738, -738, -738}}, +/* AU.AG..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -939,-1318,-1488,-1488,-1488}, +{ -249, -628, -798, -798, -798}, +{ -939,-1318,-1488,-1488,-1488}, +{ -329, -708, -878, -878, -878}}, +/* AU.AU..UA */ +{{ DEF, -429, -599, -599, -599}, +{ -639,-1018,-1188,-1188,-1188}, +{ -229, -608, -778, -778, -778}, +{ -729,-1108,-1278,-1278,-1278}, +{ -190, -569, -739, -739, -739}}}, +/* AU.C@..UA */ +{{{ DEF, -259, -239, -239, -239}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -449, -658, -638, -638, -638}, +{ -479, -688, -668, -668, -668}, +{ -429, -638, -618, -618, -618}, +{ -329, -538, -518, -518, -518}}, +/* AU.CC..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -679, -888, -868, -868, -868}, +{ -559, -768, -748, -748, -748}, +{ -729, -938, -918, -918, -918}, +{ -189, -398, -378, -378, -378}}, +/* AU.CG..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -939,-1148,-1128,-1128,-1128}, +{ -249, -458, -438, -438, -438}, +{ -939,-1148,-1128,-1128,-1128}, +{ -329, -538, -518, -518, -518}}, +/* AU.CU..UA */ +{{ DEF, -259, -239, -239, -239}, +{ -639, -848, -828, -828, -828}, +{ -229, -438, -418, -418, -418}, +{ -729, -938, -918, -918, -918}, +{ -190, -399, -379, -379, -379}}}, +/* AU.G@..UA */ +{{{ DEF, -339, -689, -689, -689}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -449, -738,-1088,-1088,-1088}, +{ -479, -768,-1118,-1118,-1118}, +{ -429, -718,-1068,-1068,-1068}, +{ -329, -618, -968, -968, -968}}, +/* AU.GC..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -679, -968,-1318,-1318,-1318}, +{ -559, -848,-1198,-1198,-1198}, +{ -729,-1018,-1368,-1368,-1368}, +{ -189, -478, -828, -828, -828}}, +/* AU.GG..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -939,-1228,-1578,-1578,-1578}, +{ -249, -538, -888, -888, -888}, +{ -939,-1228,-1578,-1578,-1578}, +{ -329, -618, -968, -968, -968}}, +/* AU.GU..UA */ +{{ DEF, -339, -689, -689, -689}, +{ -639, -928,-1278,-1278,-1278}, +{ -229, -518, -868, -868, -868}, +{ -729,-1018,-1368,-1368,-1368}, +{ -190, -479, -829, -829, -829}}}, +/* AU.U@..UA */ +{{{ DEF, -329, -329, -329, -329}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -449, -728, -728, -728, -728}, +{ -479, -758, -758, -758, -758}, +{ -429, -708, -708, -708, -708}, +{ -329, -608, -608, -608, -608}}, +/* AU.UC..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -679, -958, -958, -958, -958}, +{ -559, -838, -838, -838, -838}, +{ -729,-1008,-1008,-1008,-1008}, +{ -189, -468, -468, -468, -468}}, +/* AU.UG..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -939,-1218,-1218,-1218,-1218}, +{ -249, -528, -528, -528, -528}, +{ -939,-1218,-1218,-1218,-1218}, +{ -329, -608, -608, -608, -608}}, +/* AU.UU..UA */ +{{ DEF, -329, -329, -329, -329}, +{ -639, -918, -918, -918, -918}, +{ -229, -508, -508, -508, -508}, +{ -729,-1008,-1008,-1008,-1008}, +{ -190, -469, -469, -469, -469}}}}, +/* AU.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* AU.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* AU.A@.. @ */ +{{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AA.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AC.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AG.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}, +/* AU.AU.. @ */ +{{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}, +{ -100, -479, -649, -649, -649}}}, +/* AU.C@.. @ */ +{{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CA.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CC.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CG.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}, +/* AU.CU.. @ */ +{{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}, +{ -100, -309, -289, -289, -289}}}, +/* AU.G@.. @ */ +{{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GA.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GC.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GG.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}, +/* AU.GU.. @ */ +{{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}, +{ -100, -389, -739, -739, -739}}}, +/* AU.U@.. @ */ +{{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UA.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UC.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UG.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}, +/* AU.UU.. @ */ +{{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}, +{ -100, -379, -379, -379, -379}}}}}, +{ /* noPair */ {{{{0}}}}, +/* UA.@@..CG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* UA.@C..CG */ +{{ 0, 0, 0, 0, 0}, +{ -949, -949, -949, -949, -949}, +{ -449, -449, -449, -449, -449}, +{ -939, -939, -939, -939, -939}, +{ -739, -739, -739, -739, -739}}, +/* UA.@G..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -519, -519, -519, -519, -519}, +{ -939, -939, -939, -939, -939}, +{ -809, -809, -809, -809, -809}}, +/* UA.@U..CG */ +{{ 0, 0, 0, 0, 0}, +{-1029,-1029,-1029,-1029,-1029}, +{ -669, -669, -669, -669, -669}, +{ -939, -939, -939, -939, -939}, +{ -859, -859, -859, -859, -859}}}, +/* UA.A@..CG */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..CG */ +{{ DEF, -399, -629, -889, -589}, +{-1079,-1428,-1658,-1918,-1618}, +{ -569, -918,-1148,-1408,-1108}, +{ -989,-1338,-1568,-1828,-1528}, +{ -859,-1208,-1438,-1698,-1398}}, +/* UA.AC..CG */ +{{ DEF, -399, -629, -889, -589}, +{ -999,-1348,-1578,-1838,-1538}, +{ -499, -848,-1078,-1338,-1038}, +{ -989,-1338,-1568,-1828,-1528}, +{ -789,-1138,-1368,-1628,-1328}}, +/* UA.AG..CG */ +{{ DEF, -399, -629, -889, -589}, +{-1079,-1428,-1658,-1918,-1618}, +{ -569, -918,-1148,-1408,-1108}, +{ -989,-1338,-1568,-1828,-1528}, +{ -859,-1208,-1438,-1698,-1398}}, +/* UA.AU..CG */ +{{ DEF, -399, -629, -889, -589}, +{-1079,-1428,-1658,-1918,-1618}, +{ -719,-1068,-1298,-1558,-1258}, +{ -989,-1338,-1568,-1828,-1528}, +{ -909,-1258,-1488,-1748,-1448}}}, +/* UA.C@..CG */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..CG */ +{{ DEF, -429, -509, -199, -179}, +{-1079,-1458,-1538,-1228,-1208}, +{ -569, -948,-1028, -718, -698}, +{ -989,-1368,-1448,-1138,-1118}, +{ -859,-1238,-1318,-1008, -988}}, +/* UA.CC..CG */ +{{ DEF, -429, -509, -199, -179}, +{ -999,-1378,-1458,-1148,-1128}, +{ -499, -878, -958, -648, -628}, +{ -989,-1368,-1448,-1138,-1118}, +{ -789,-1168,-1248, -938, -918}}, +/* UA.CG..CG */ +{{ DEF, -429, -509, -199, -179}, +{-1079,-1458,-1538,-1228,-1208}, +{ -569, -948,-1028, -718, -698}, +{ -989,-1368,-1448,-1138,-1118}, +{ -859,-1238,-1318,-1008, -988}}, +/* UA.CU..CG */ +{{ DEF, -429, -509, -199, -179}, +{-1079,-1458,-1538,-1228,-1208}, +{ -719,-1098,-1178, -868, -848}, +{ -989,-1368,-1448,-1138,-1118}, +{ -909,-1288,-1368,-1058,-1038}}}, +/* UA.G@..CG */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..CG */ +{{ DEF, -379, -679, -889, -679}, +{-1079,-1408,-1708,-1918,-1708}, +{ -569, -898,-1198,-1408,-1198}, +{ -989,-1318,-1618,-1828,-1618}, +{ -859,-1188,-1488,-1698,-1488}}, +/* UA.GC..CG */ +{{ DEF, -379, -679, -889, -679}, +{ -999,-1328,-1628,-1838,-1628}, +{ -499, -828,-1128,-1338,-1128}, +{ -989,-1318,-1618,-1828,-1618}, +{ -789,-1118,-1418,-1628,-1418}}, +/* UA.GG..CG */ +{{ DEF, -379, -679, -889, -679}, +{-1079,-1408,-1708,-1918,-1708}, +{ -569, -898,-1198,-1408,-1198}, +{ -989,-1318,-1618,-1828,-1618}, +{ -859,-1188,-1488,-1698,-1488}}, +/* UA.GU..CG */ +{{ DEF, -379, -679, -889, -679}, +{-1079,-1408,-1708,-1918,-1708}, +{ -719,-1048,-1348,-1558,-1348}, +{ -989,-1318,-1618,-1828,-1618}, +{ -909,-1238,-1538,-1748,-1538}}}, +/* UA.U@..CG */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..CG */ +{{ DEF, -279, -139, -279, -140}, +{-1079,-1308,-1168,-1308,-1169}, +{ -569, -798, -658, -798, -659}, +{ -989,-1218,-1078,-1218,-1079}, +{ -859,-1088, -948,-1088, -949}}, +/* UA.UC..CG */ +{{ DEF, -279, -139, -279, -140}, +{ -999,-1228,-1088,-1228,-1089}, +{ -499, -728, -588, -728, -589}, +{ -989,-1218,-1078,-1218,-1079}, +{ -789,-1018, -878,-1018, -879}}, +/* UA.UG..CG */ +{{ DEF, -279, -139, -279, -140}, +{-1079,-1308,-1168,-1308,-1169}, +{ -569, -798, -658, -798, -659}, +{ -989,-1218,-1078,-1218,-1079}, +{ -859,-1088, -948,-1088, -949}}, +/* UA.UU..CG */ +{{ DEF, -279, -139, -279, -140}, +{-1079,-1308,-1168,-1308,-1169}, +{ -719, -948, -808, -948, -809}, +{ -989,-1218,-1078,-1218,-1079}, +{ -909,-1138, -998,-1138, -999}}}}, +/* UA.@@..GC */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..GC */ +{{ 0, 0, 0, 0, 0}, +{ -519, -519, -519, -519, -519}, +{ -719, -719, -719, -719, -719}, +{ -709, -709, -709, -709, -709}, +{ -499, -499, -499, -499, -499}}, +/* UA.@C..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -309, -309, -309, -309, -309}, +{ -739, -739, -739, -739, -739}, +{ -499, -499, -499, -499, -499}}, +/* UA.@G..GC */ +{{ 0, 0, 0, 0, 0}, +{ -559, -559, -559, -559, -559}, +{ -309, -309, -309, -309, -309}, +{ -619, -619, -619, -619, -619}, +{ -499, -499, -499, -499, -499}}, +/* UA.@U..GC */ +{{ 0, 0, 0, 0, 0}, +{ -879, -879, -879, -879, -879}, +{ -389, -389, -389, -389, -389}, +{ -739, -739, -739, -739, -739}, +{ -569, -569, -569, -569, -569}}}, +/* UA.A@..GC */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..GC */ +{{ DEF, -399, -629, -889, -589}, +{ -569, -918,-1148,-1408,-1108}, +{ -769,-1118,-1348,-1608,-1308}, +{ -759,-1108,-1338,-1598,-1298}, +{ -549, -898,-1128,-1388,-1088}}, +/* UA.AC..GC */ +{{ DEF, -399, -629, -889, -589}, +{ -929,-1278,-1508,-1768,-1468}, +{ -359, -708, -938,-1198, -898}, +{ -789,-1138,-1368,-1628,-1328}, +{ -549, -898,-1128,-1388,-1088}}, +/* UA.AG..GC */ +{{ DEF, -399, -629, -889, -589}, +{ -609, -958,-1188,-1448,-1148}, +{ -359, -708, -938,-1198, -898}, +{ -669,-1018,-1248,-1508,-1208}, +{ -549, -898,-1128,-1388,-1088}}, +/* UA.AU..GC */ +{{ DEF, -399, -629, -889, -589}, +{ -929,-1278,-1508,-1768,-1468}, +{ -439, -788,-1018,-1278, -978}, +{ -789,-1138,-1368,-1628,-1328}, +{ -619, -968,-1198,-1458,-1158}}}, +/* UA.C@..GC */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..GC */ +{{ DEF, -429, -509, -199, -179}, +{ -569, -948,-1028, -718, -698}, +{ -769,-1148,-1228, -918, -898}, +{ -759,-1138,-1218, -908, -888}, +{ -549, -928,-1008, -698, -678}}, +/* UA.CC..GC */ +{{ DEF, -429, -509, -199, -179}, +{ -929,-1308,-1388,-1078,-1058}, +{ -359, -738, -818, -508, -488}, +{ -789,-1168,-1248, -938, -918}, +{ -549, -928,-1008, -698, -678}}, +/* UA.CG..GC */ +{{ DEF, -429, -509, -199, -179}, +{ -609, -988,-1068, -758, -738}, +{ -359, -738, -818, -508, -488}, +{ -669,-1048,-1128, -818, -798}, +{ -549, -928,-1008, -698, -678}}, +/* UA.CU..GC */ +{{ DEF, -429, -509, -199, -179}, +{ -929,-1308,-1388,-1078,-1058}, +{ -439, -818, -898, -588, -568}, +{ -789,-1168,-1248, -938, -918}, +{ -619, -998,-1078, -768, -748}}}, +/* UA.G@..GC */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..GC */ +{{ DEF, -379, -679, -889, -679}, +{ -569, -898,-1198,-1408,-1198}, +{ -769,-1098,-1398,-1608,-1398}, +{ -759,-1088,-1388,-1598,-1388}, +{ -549, -878,-1178,-1388,-1178}}, +/* UA.GC..GC */ +{{ DEF, -379, -679, -889, -679}, +{ -929,-1258,-1558,-1768,-1558}, +{ -359, -688, -988,-1198, -988}, +{ -789,-1118,-1418,-1628,-1418}, +{ -549, -878,-1178,-1388,-1178}}, +/* UA.GG..GC */ +{{ DEF, -379, -679, -889, -679}, +{ -609, -938,-1238,-1448,-1238}, +{ -359, -688, -988,-1198, -988}, +{ -669, -998,-1298,-1508,-1298}, +{ -549, -878,-1178,-1388,-1178}}, +/* UA.GU..GC */ +{{ DEF, -379, -679, -889, -679}, +{ -929,-1258,-1558,-1768,-1558}, +{ -439, -768,-1068,-1278,-1068}, +{ -789,-1118,-1418,-1628,-1418}, +{ -619, -948,-1248,-1458,-1248}}}, +/* UA.U@..GC */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..GC */ +{{ DEF, -279, -139, -279, -140}, +{ -569, -798, -658, -798, -659}, +{ -769, -998, -858, -998, -859}, +{ -759, -988, -848, -988, -849}, +{ -549, -778, -638, -778, -639}}, +/* UA.UC..GC */ +{{ DEF, -279, -139, -279, -140}, +{ -929,-1158,-1018,-1158,-1019}, +{ -359, -588, -448, -588, -449}, +{ -789,-1018, -878,-1018, -879}, +{ -549, -778, -638, -778, -639}}, +/* UA.UG..GC */ +{{ DEF, -279, -139, -279, -140}, +{ -609, -838, -698, -838, -699}, +{ -359, -588, -448, -588, -449}, +{ -669, -898, -758, -898, -759}, +{ -549, -778, -638, -778, -639}}, +/* UA.UU..GC */ +{{ DEF, -279, -139, -279, -140}, +{ -929,-1158,-1018,-1158,-1019}, +{ -439, -668, -528, -668, -529}, +{ -789,-1018, -878,-1018, -879}, +{ -619, -848, -708, -848, -709}}}}, +/* UA.@@..GU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..GU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* UA.@C..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UA.@G..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UA.@U..GU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* UA.A@..GU */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..GU */ +{{ DEF, -399, -629, -889, -589}, +{ -479, -828,-1058,-1318,-1018}, +{ -309, -658, -888,-1148, -848}, +{ -389, -738, -968,-1228, -928}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AC..GU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AG..GU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AU..GU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}}, +/* UA.C@..GU */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..GU */ +{{ DEF, -429, -509, -199, -179}, +{ -479, -858, -938, -628, -608}, +{ -309, -688, -768, -458, -438}, +{ -389, -768, -848, -538, -518}, +{ -379, -758, -838, -528, -508}}, +/* UA.CC..GU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}, +/* UA.CG..GU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}, +/* UA.CU..GU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}}, +/* UA.G@..GU */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..GU */ +{{ DEF, -379, -679, -889, -679}, +{ -479, -808,-1108,-1318,-1108}, +{ -309, -638, -938,-1148, -938}, +{ -389, -718,-1018,-1228,-1018}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GC..GU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GG..GU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GU..GU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}}, +/* UA.U@..GU */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..GU */ +{{ DEF, -279, -139, -279, -140}, +{ -479, -708, -568, -708, -569}, +{ -309, -538, -398, -538, -399}, +{ -389, -618, -478, -618, -479}, +{ -379, -608, -468, -608, -469}}, +/* UA.UC..GU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}, +/* UA.UG..GU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}, +/* UA.UU..GU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}}}, +/* UA.@@..UG */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..UG */ +{{ 0, 0, 0, 0, 0}, +{ -719, -719, -719, -719, -719}, +{ -479, -479, -479, -479, -479}, +{ -659, -659, -659, -659, -659}, +{ -549, -549, -549, -549, -549}}, +/* UA.@C..UG */ +{{ 0, 0, 0, 0, 0}, +{ -789, -789, -789, -789, -789}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -439, -439, -439, -439, -439}}, +/* UA.@G..UG */ +{{ 0, 0, 0, 0, 0}, +{ -959, -959, -959, -959, -959}, +{ -359, -359, -359, -359, -359}, +{ -919, -919, -919, -919, -919}, +{ -549, -549, -549, -549, -549}}, +/* UA.@U..UG */ +{{ 0, 0, 0, 0, 0}, +{ -809, -809, -809, -809, -809}, +{ -479, -479, -479, -479, -479}, +{ -809, -809, -809, -809, -809}, +{ -359, -359, -359, -359, -359}}}, +/* UA.A@..UG */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..UG */ +{{ DEF, -399, -629, -889, -589}, +{ -769,-1118,-1348,-1608,-1308}, +{ -529, -878,-1108,-1368,-1068}, +{ -709,-1058,-1288,-1548,-1248}, +{ -599, -948,-1178,-1438,-1138}}, +/* UA.AC..UG */ +{{ DEF, -399, -629, -889, -589}, +{ -839,-1188,-1418,-1678,-1378}, +{ -529, -878,-1108,-1368,-1068}, +{ -859,-1208,-1438,-1698,-1398}, +{ -489, -838,-1068,-1328,-1028}}, +/* UA.AG..UG */ +{{ DEF, -399, -629, -889, -589}, +{-1009,-1358,-1588,-1848,-1548}, +{ -409, -758, -988,-1248, -948}, +{ -969,-1318,-1548,-1808,-1508}, +{ -599, -948,-1178,-1438,-1138}}, +/* UA.AU..UG */ +{{ DEF, -399, -629, -889, -589}, +{ -859,-1208,-1438,-1698,-1398}, +{ -529, -878,-1108,-1368,-1068}, +{ -859,-1208,-1438,-1698,-1398}, +{ -409, -758, -988,-1248, -948}}}, +/* UA.C@..UG */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..UG */ +{{ DEF, -429, -509, -199, -179}, +{ -769,-1148,-1228, -918, -898}, +{ -529, -908, -988, -678, -658}, +{ -709,-1088,-1168, -858, -838}, +{ -599, -978,-1058, -748, -728}}, +/* UA.CC..UG */ +{{ DEF, -429, -509, -199, -179}, +{ -839,-1218,-1298, -988, -968}, +{ -529, -908, -988, -678, -658}, +{ -859,-1238,-1318,-1008, -988}, +{ -489, -868, -948, -638, -618}}, +/* UA.CG..UG */ +{{ DEF, -429, -509, -199, -179}, +{-1009,-1388,-1468,-1158,-1138}, +{ -409, -788, -868, -558, -538}, +{ -969,-1348,-1428,-1118,-1098}, +{ -599, -978,-1058, -748, -728}}, +/* UA.CU..UG */ +{{ DEF, -429, -509, -199, -179}, +{ -859,-1238,-1318,-1008, -988}, +{ -529, -908, -988, -678, -658}, +{ -859,-1238,-1318,-1008, -988}, +{ -409, -788, -868, -558, -538}}}, +/* UA.G@..UG */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..UG */ +{{ DEF, -379, -679, -889, -679}, +{ -769,-1098,-1398,-1608,-1398}, +{ -529, -858,-1158,-1368,-1158}, +{ -709,-1038,-1338,-1548,-1338}, +{ -599, -928,-1228,-1438,-1228}}, +/* UA.GC..UG */ +{{ DEF, -379, -679, -889, -679}, +{ -839,-1168,-1468,-1678,-1468}, +{ -529, -858,-1158,-1368,-1158}, +{ -859,-1188,-1488,-1698,-1488}, +{ -489, -818,-1118,-1328,-1118}}, +/* UA.GG..UG */ +{{ DEF, -379, -679, -889, -679}, +{-1009,-1338,-1638,-1848,-1638}, +{ -409, -738,-1038,-1248,-1038}, +{ -969,-1298,-1598,-1808,-1598}, +{ -599, -928,-1228,-1438,-1228}}, +/* UA.GU..UG */ +{{ DEF, -379, -679, -889, -679}, +{ -859,-1188,-1488,-1698,-1488}, +{ -529, -858,-1158,-1368,-1158}, +{ -859,-1188,-1488,-1698,-1488}, +{ -409, -738,-1038,-1248,-1038}}}, +/* UA.U@..UG */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..UG */ +{{ DEF, -279, -139, -279, -140}, +{ -769, -998, -858, -998, -859}, +{ -529, -758, -618, -758, -619}, +{ -709, -938, -798, -938, -799}, +{ -599, -828, -688, -828, -689}}, +/* UA.UC..UG */ +{{ DEF, -279, -139, -279, -140}, +{ -839,-1068, -928,-1068, -929}, +{ -529, -758, -618, -758, -619}, +{ -859,-1088, -948,-1088, -949}, +{ -489, -718, -578, -718, -579}}, +/* UA.UG..UG */ +{{ DEF, -279, -139, -279, -140}, +{-1009,-1238,-1098,-1238,-1099}, +{ -409, -638, -498, -638, -499}, +{ -969,-1198,-1058,-1198,-1059}, +{ -599, -828, -688, -828, -689}}, +/* UA.UU..UG */ +{{ DEF, -279, -139, -279, -140}, +{ -859,-1088, -948,-1088, -949}, +{ -529, -758, -618, -758, -619}, +{ -859,-1088, -948,-1088, -949}, +{ -409, -638, -498, -638, -499}}}}, +/* UA.@@..AU */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..AU */ +{{ 0, 0, 0, 0, 0}, +{ -429, -429, -429, -429, -429}, +{ -259, -259, -259, -259, -259}, +{ -339, -339, -339, -339, -339}, +{ -329, -329, -329, -329, -329}}, +/* UA.@C..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UA.@G..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}, +/* UA.@U..AU */ +{{ 0, 0, 0, 0, 0}, +{ -599, -599, -599, -599, -599}, +{ -239, -239, -239, -239, -239}, +{ -689, -689, -689, -689, -689}, +{ -329, -329, -329, -329, -329}}}, +/* UA.A@..AU */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..AU */ +{{ DEF, -399, -629, -889, -589}, +{ -479, -828,-1058,-1318,-1018}, +{ -309, -658, -888,-1148, -848}, +{ -389, -738, -968,-1228, -928}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AC..AU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AG..AU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}, +/* UA.AU..AU */ +{{ DEF, -399, -629, -889, -589}, +{ -649, -998,-1228,-1488,-1188}, +{ -289, -638, -868,-1128, -828}, +{ -739,-1088,-1318,-1578,-1278}, +{ -379, -728, -958,-1218, -918}}}, +/* UA.C@..AU */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..AU */ +{{ DEF, -429, -509, -199, -179}, +{ -479, -858, -938, -628, -608}, +{ -309, -688, -768, -458, -438}, +{ -389, -768, -848, -538, -518}, +{ -379, -758, -838, -528, -508}}, +/* UA.CC..AU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}, +/* UA.CG..AU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}, +/* UA.CU..AU */ +{{ DEF, -429, -509, -199, -179}, +{ -649,-1028,-1108, -798, -778}, +{ -289, -668, -748, -438, -418}, +{ -739,-1118,-1198, -888, -868}, +{ -379, -758, -838, -528, -508}}}, +/* UA.G@..AU */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..AU */ +{{ DEF, -379, -679, -889, -679}, +{ -479, -808,-1108,-1318,-1108}, +{ -309, -638, -938,-1148, -938}, +{ -389, -718,-1018,-1228,-1018}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GC..AU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GG..AU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}, +/* UA.GU..AU */ +{{ DEF, -379, -679, -889, -679}, +{ -649, -978,-1278,-1488,-1278}, +{ -289, -618, -918,-1128, -918}, +{ -739,-1068,-1368,-1578,-1368}, +{ -379, -708,-1008,-1218,-1008}}}, +/* UA.U@..AU */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..AU */ +{{ DEF, -279, -139, -279, -140}, +{ -479, -708, -568, -708, -569}, +{ -309, -538, -398, -538, -399}, +{ -389, -618, -478, -618, -479}, +{ -379, -608, -468, -608, -469}}, +/* UA.UC..AU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}, +/* UA.UG..AU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}, +/* UA.UU..AU */ +{{ DEF, -279, -139, -279, -140}, +{ -649, -878, -738, -878, -739}, +{ -289, -518, -378, -518, -379}, +{ -739, -968, -828, -968, -829}, +{ -379, -608, -468, -608, -469}}}}, +/* UA.@@..UA */ +{{{{ 0, 0, 0, 0, 0}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A..UA */ +{{ 0, 0, 0, 0, 0}, +{ -399, -399, -399, -399, -399}, +{ -429, -429, -429, -429, -429}, +{ -379, -379, -379, -379, -379}, +{ -279, -279, -279, -279, -279}}, +/* UA.@C..UA */ +{{ 0, 0, 0, 0, 0}, +{ -629, -629, -629, -629, -629}, +{ -509, -509, -509, -509, -509}, +{ -679, -679, -679, -679, -679}, +{ -139, -139, -139, -139, -139}}, +/* UA.@G..UA */ +{{ 0, 0, 0, 0, 0}, +{ -889, -889, -889, -889, -889}, +{ -199, -199, -199, -199, -199}, +{ -889, -889, -889, -889, -889}, +{ -279, -279, -279, -279, -279}}, +/* UA.@U..UA */ +{{ 0, 0, 0, 0, 0}, +{ -589, -589, -589, -589, -589}, +{ -179, -179, -179, -179, -179}, +{ -679, -679, -679, -679, -679}, +{ -140, -140, -140, -140, -140}}}, +/* UA.A@..UA */ +{{{ DEF, -399, -629, -889, -589}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA..UA */ +{{ DEF, -399, -629, -889, -589}, +{ -449, -798,-1028,-1288, -988}, +{ -479, -828,-1058,-1318,-1018}, +{ -429, -778,-1008,-1268, -968}, +{ -329, -678, -908,-1168, -868}}, +/* UA.AC..UA */ +{{ DEF, -399, -629, -889, -589}, +{ -679,-1028,-1258,-1518,-1218}, +{ -559, -908,-1138,-1398,-1098}, +{ -729,-1078,-1308,-1568,-1268}, +{ -189, -538, -768,-1028, -728}}, +/* UA.AG..UA */ +{{ DEF, -399, -629, -889, -589}, +{ -939,-1288,-1518,-1778,-1478}, +{ -249, -598, -828,-1088, -788}, +{ -939,-1288,-1518,-1778,-1478}, +{ -329, -678, -908,-1168, -868}}, +/* UA.AU..UA */ +{{ DEF, -399, -629, -889, -589}, +{ -639, -988,-1218,-1478,-1178}, +{ -229, -578, -808,-1068, -768}, +{ -729,-1078,-1308,-1568,-1268}, +{ -190, -539, -769,-1029, -729}}}, +/* UA.C@..UA */ +{{{ DEF, -429, -509, -199, -179}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA..UA */ +{{ DEF, -429, -509, -199, -179}, +{ -449, -828, -908, -598, -578}, +{ -479, -858, -938, -628, -608}, +{ -429, -808, -888, -578, -558}, +{ -329, -708, -788, -478, -458}}, +/* UA.CC..UA */ +{{ DEF, -429, -509, -199, -179}, +{ -679,-1058,-1138, -828, -808}, +{ -559, -938,-1018, -708, -688}, +{ -729,-1108,-1188, -878, -858}, +{ -189, -568, -648, -338, -318}}, +/* UA.CG..UA */ +{{ DEF, -429, -509, -199, -179}, +{ -939,-1318,-1398,-1088,-1068}, +{ -249, -628, -708, -398, -378}, +{ -939,-1318,-1398,-1088,-1068}, +{ -329, -708, -788, -478, -458}}, +/* UA.CU..UA */ +{{ DEF, -429, -509, -199, -179}, +{ -639,-1018,-1098, -788, -768}, +{ -229, -608, -688, -378, -358}, +{ -729,-1108,-1188, -878, -858}, +{ -190, -569, -649, -339, -319}}}, +/* UA.G@..UA */ +{{{ DEF, -379, -679, -889, -679}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA..UA */ +{{ DEF, -379, -679, -889, -679}, +{ -449, -778,-1078,-1288,-1078}, +{ -479, -808,-1108,-1318,-1108}, +{ -429, -758,-1058,-1268,-1058}, +{ -329, -658, -958,-1168, -958}}, +/* UA.GC..UA */ +{{ DEF, -379, -679, -889, -679}, +{ -679,-1008,-1308,-1518,-1308}, +{ -559, -888,-1188,-1398,-1188}, +{ -729,-1058,-1358,-1568,-1358}, +{ -189, -518, -818,-1028, -818}}, +/* UA.GG..UA */ +{{ DEF, -379, -679, -889, -679}, +{ -939,-1268,-1568,-1778,-1568}, +{ -249, -578, -878,-1088, -878}, +{ -939,-1268,-1568,-1778,-1568}, +{ -329, -658, -958,-1168, -958}}, +/* UA.GU..UA */ +{{ DEF, -379, -679, -889, -679}, +{ -639, -968,-1268,-1478,-1268}, +{ -229, -558, -858,-1068, -858}, +{ -729,-1058,-1358,-1568,-1358}, +{ -190, -519, -819,-1029, -819}}}, +/* UA.U@..UA */ +{{{ DEF, -279, -139, -279, -140}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA..UA */ +{{ DEF, -279, -139, -279, -140}, +{ -449, -678, -538, -678, -539}, +{ -479, -708, -568, -708, -569}, +{ -429, -658, -518, -658, -519}, +{ -329, -558, -418, -558, -419}}, +/* UA.UC..UA */ +{{ DEF, -279, -139, -279, -140}, +{ -679, -908, -768, -908, -769}, +{ -559, -788, -648, -788, -649}, +{ -729, -958, -818, -958, -819}, +{ -189, -418, -278, -418, -279}}, +/* UA.UG..UA */ +{{ DEF, -279, -139, -279, -140}, +{ -939,-1168,-1028,-1168,-1029}, +{ -249, -478, -338, -478, -339}, +{ -939,-1168,-1028,-1168,-1029}, +{ -329, -558, -418, -558, -419}}, +/* UA.UU..UA */ +{{ DEF, -279, -139, -279, -140}, +{ -639, -868, -728, -868, -729}, +{ -229, -458, -318, -458, -319}, +{ -729, -958, -818, -958, -819}, +{ -190, -419, -279, -419, -280}}}}, +/* UA.@@.. @ */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@A.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@C.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@G.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}, +/* UA.@U.. @ */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}, +{ DEF, DEF, DEF, DEF, DEF}}}, +/* UA.A@.. @ */ +{{{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AA.. @ */ +{{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AC.. @ */ +{{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AG.. @ */ +{{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}, +/* UA.AU.. @ */ +{{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}, +{ -100, -449, -679, -939, -639}}}, +/* UA.C@.. @ */ +{{{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CA.. @ */ +{{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CC.. @ */ +{{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CG.. @ */ +{{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}, +/* UA.CU.. @ */ +{{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}, +{ -100, -479, -559, -249, -229}}}, +/* UA.G@.. @ */ +{{{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GA.. @ */ +{{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GC.. @ */ +{{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GG.. @ */ +{{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}, +/* UA.GU.. @ */ +{{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}, +{ -100, -429, -729, -939, -729}}}, +/* UA.U@.. @ */ +{{{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UA.. @ */ +{{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UC.. @ */ +{{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UG.. @ */ +{{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}, +/* UA.UU.. @ */ +{{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}, +{ -100, -329, -189, -329, -190}}}}}, +{ /* noPair */ {{{{0}}}}, +/* @.@@..CG */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.@C..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -999, -999, -999, -999, -999}, +{ -499, -499, -499, -499, -499}, +{ -989, -989, -989, -989, -989}, +{ -789, -789, -789, -789, -789}}, +/* @.@G..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.@U..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -719, -719, -719, -719, -719}, +{ -989, -989, -989, -989, -989}, +{ -909, -909, -909, -909, -909}}}, +/* @.A@..CG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.AC..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -999, -999, -999, -999, -999}, +{ -499, -499, -499, -499, -499}, +{ -989, -989, -989, -989, -989}, +{ -789, -789, -789, -789, -789}}, +/* @.AG..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.AU..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -719, -719, -719, -719, -719}, +{ -989, -989, -989, -989, -989}, +{ -909, -909, -909, -909, -909}}}, +/* @.C@..CG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.CC..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -999, -999, -999, -999, -999}, +{ -499, -499, -499, -499, -499}, +{ -989, -989, -989, -989, -989}, +{ -789, -789, -789, -789, -789}}, +/* @.CG..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.CU..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -719, -719, -719, -719, -719}, +{ -989, -989, -989, -989, -989}, +{ -909, -909, -909, -909, -909}}}, +/* @.G@..CG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.GC..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -999, -999, -999, -999, -999}, +{ -499, -499, -499, -499, -499}, +{ -989, -989, -989, -989, -989}, +{ -789, -789, -789, -789, -789}}, +/* @.GG..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.GU..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -719, -719, -719, -719, -719}, +{ -989, -989, -989, -989, -989}, +{ -909, -909, -909, -909, -909}}}, +/* @.U@..CG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.UC..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -999, -999, -999, -999, -999}, +{ -499, -499, -499, -499, -499}, +{ -989, -989, -989, -989, -989}, +{ -789, -789, -789, -789, -789}}, +/* @.UG..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -569, -569, -569, -569, -569}, +{ -989, -989, -989, -989, -989}, +{ -859, -859, -859, -859, -859}}, +/* @.UU..CG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1079,-1079,-1079,-1079,-1079}, +{ -719, -719, -719, -719, -719}, +{ -989, -989, -989, -989, -989}, +{ -909, -909, -909, -909, -909}}}}, +/* @.@@..GC */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -569, -569, -569, -569, -569}, +{ -769, -769, -769, -769, -769}, +{ -759, -759, -759, -759, -759}, +{ -549, -549, -549, -549, -549}}, +/* @.@C..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -359, -359, -359, -359, -359}, +{ -789, -789, -789, -789, -789}, +{ -549, -549, -549, -549, -549}}, +/* @.@G..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -609, -609, -609, -609, -609}, +{ -359, -359, -359, -359, -359}, +{ -669, -669, -669, -669, -669}, +{ -549, -549, -549, -549, -549}}, +/* @.@U..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -439, -439, -439, -439, -439}, +{ -789, -789, -789, -789, -789}, +{ -619, -619, -619, -619, -619}}}, +/* @.A@..GC */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -569, -569, -569, -569, -569}, +{ -769, -769, -769, -769, -769}, +{ -759, -759, -759, -759, -759}, +{ -549, -549, -549, -549, -549}}, +/* @.AC..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -359, -359, -359, -359, -359}, +{ -789, -789, -789, -789, -789}, +{ -549, -549, -549, -549, -549}}, +/* @.AG..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -609, -609, -609, -609, -609}, +{ -359, -359, -359, -359, -359}, +{ -669, -669, -669, -669, -669}, +{ -549, -549, -549, -549, -549}}, +/* @.AU..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -439, -439, -439, -439, -439}, +{ -789, -789, -789, -789, -789}, +{ -619, -619, -619, -619, -619}}}, +/* @.C@..GC */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -569, -569, -569, -569, -569}, +{ -769, -769, -769, -769, -769}, +{ -759, -759, -759, -759, -759}, +{ -549, -549, -549, -549, -549}}, +/* @.CC..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -359, -359, -359, -359, -359}, +{ -789, -789, -789, -789, -789}, +{ -549, -549, -549, -549, -549}}, +/* @.CG..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -609, -609, -609, -609, -609}, +{ -359, -359, -359, -359, -359}, +{ -669, -669, -669, -669, -669}, +{ -549, -549, -549, -549, -549}}, +/* @.CU..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -439, -439, -439, -439, -439}, +{ -789, -789, -789, -789, -789}, +{ -619, -619, -619, -619, -619}}}, +/* @.G@..GC */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -569, -569, -569, -569, -569}, +{ -769, -769, -769, -769, -769}, +{ -759, -759, -759, -759, -759}, +{ -549, -549, -549, -549, -549}}, +/* @.GC..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -359, -359, -359, -359, -359}, +{ -789, -789, -789, -789, -789}, +{ -549, -549, -549, -549, -549}}, +/* @.GG..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -609, -609, -609, -609, -609}, +{ -359, -359, -359, -359, -359}, +{ -669, -669, -669, -669, -669}, +{ -549, -549, -549, -549, -549}}, +/* @.GU..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -439, -439, -439, -439, -439}, +{ -789, -789, -789, -789, -789}, +{ -619, -619, -619, -619, -619}}}, +/* @.U@..GC */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -569, -569, -569, -569, -569}, +{ -769, -769, -769, -769, -769}, +{ -759, -759, -759, -759, -759}, +{ -549, -549, -549, -549, -549}}, +/* @.UC..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -359, -359, -359, -359, -359}, +{ -789, -789, -789, -789, -789}, +{ -549, -549, -549, -549, -549}}, +/* @.UG..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -609, -609, -609, -609, -609}, +{ -359, -359, -359, -359, -359}, +{ -669, -669, -669, -669, -669}, +{ -549, -549, -549, -549, -549}}, +/* @.UU..GC */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -929, -929, -929, -929, -929}, +{ -439, -439, -439, -439, -439}, +{ -789, -789, -789, -789, -789}, +{ -619, -619, -619, -619, -619}}}}, +/* @.@@..GU */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.@C..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.@G..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.@U..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.A@..GU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.AC..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.AG..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.AU..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.C@..GU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.CC..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.CG..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.CU..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.G@..GU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.GC..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.GG..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.GU..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.U@..GU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.UC..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.UG..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.UU..GU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}}, +/* @.@@..UG */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -769, -769, -769, -769, -769}, +{ -529, -529, -529, -529, -529}, +{ -709, -709, -709, -709, -709}, +{ -599, -599, -599, -599, -599}}, +/* @.@C..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -839, -839, -839, -839, -839}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -489, -489, -489, -489, -489}}, +/* @.@G..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1009,-1009,-1009,-1009,-1009}, +{ -409, -409, -409, -409, -409}, +{ -969, -969, -969, -969, -969}, +{ -599, -599, -599, -599, -599}}, +/* @.@U..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -859, -859, -859, -859, -859}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -409, -409, -409, -409, -409}}}, +/* @.A@..UG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -769, -769, -769, -769, -769}, +{ -529, -529, -529, -529, -529}, +{ -709, -709, -709, -709, -709}, +{ -599, -599, -599, -599, -599}}, +/* @.AC..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -839, -839, -839, -839, -839}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -489, -489, -489, -489, -489}}, +/* @.AG..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1009,-1009,-1009,-1009,-1009}, +{ -409, -409, -409, -409, -409}, +{ -969, -969, -969, -969, -969}, +{ -599, -599, -599, -599, -599}}, +/* @.AU..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -859, -859, -859, -859, -859}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -409, -409, -409, -409, -409}}}, +/* @.C@..UG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -769, -769, -769, -769, -769}, +{ -529, -529, -529, -529, -529}, +{ -709, -709, -709, -709, -709}, +{ -599, -599, -599, -599, -599}}, +/* @.CC..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -839, -839, -839, -839, -839}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -489, -489, -489, -489, -489}}, +/* @.CG..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1009,-1009,-1009,-1009,-1009}, +{ -409, -409, -409, -409, -409}, +{ -969, -969, -969, -969, -969}, +{ -599, -599, -599, -599, -599}}, +/* @.CU..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -859, -859, -859, -859, -859}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -409, -409, -409, -409, -409}}}, +/* @.G@..UG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -769, -769, -769, -769, -769}, +{ -529, -529, -529, -529, -529}, +{ -709, -709, -709, -709, -709}, +{ -599, -599, -599, -599, -599}}, +/* @.GC..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -839, -839, -839, -839, -839}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -489, -489, -489, -489, -489}}, +/* @.GG..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1009,-1009,-1009,-1009,-1009}, +{ -409, -409, -409, -409, -409}, +{ -969, -969, -969, -969, -969}, +{ -599, -599, -599, -599, -599}}, +/* @.GU..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -859, -859, -859, -859, -859}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -409, -409, -409, -409, -409}}}, +/* @.U@..UG */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -769, -769, -769, -769, -769}, +{ -529, -529, -529, -529, -529}, +{ -709, -709, -709, -709, -709}, +{ -599, -599, -599, -599, -599}}, +/* @.UC..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -839, -839, -839, -839, -839}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -489, -489, -489, -489, -489}}, +/* @.UG..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{-1009,-1009,-1009,-1009,-1009}, +{ -409, -409, -409, -409, -409}, +{ -969, -969, -969, -969, -969}, +{ -599, -599, -599, -599, -599}}, +/* @.UU..UG */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -859, -859, -859, -859, -859}, +{ -529, -529, -529, -529, -529}, +{ -859, -859, -859, -859, -859}, +{ -409, -409, -409, -409, -409}}}}, +/* @.@@..AU */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.@C..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.@G..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.@U..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.A@..AU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.AC..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.AG..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.AU..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.C@..AU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.CC..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.CG..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.CU..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.G@..AU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.GC..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.GG..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.GU..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}, +/* @.U@..AU */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -479, -479, -479, -479, -479}, +{ -309, -309, -309, -309, -309}, +{ -389, -389, -389, -389, -389}, +{ -379, -379, -379, -379, -379}}, +/* @.UC..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.UG..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}, +/* @.UU..AU */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -649, -649, -649, -649, -649}, +{ -289, -289, -289, -289, -289}, +{ -739, -739, -739, -739, -739}, +{ -379, -379, -379, -379, -379}}}}, +/* @.@@..UA */ +{{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -449, -449, -449, -449, -449}, +{ -479, -479, -479, -479, -479}, +{ -429, -429, -429, -429, -429}, +{ -329, -329, -329, -329, -329}}, +/* @.@C..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -679, -679, -679, -679, -679}, +{ -559, -559, -559, -559, -559}, +{ -729, -729, -729, -729, -729}, +{ -189, -189, -189, -189, -189}}, +/* @.@G..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -939, -939, -939, -939, -939}, +{ -249, -249, -249, -249, -249}, +{ -939, -939, -939, -939, -939}, +{ -329, -329, -329, -329, -329}}, +/* @.@U..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -639, -639, -639, -639, -639}, +{ -229, -229, -229, -229, -229}, +{ -729, -729, -729, -729, -729}, +{ -190, -190, -190, -190, -190}}}, +/* @.A@..UA */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -449, -449, -449, -449, -449}, +{ -479, -479, -479, -479, -479}, +{ -429, -429, -429, -429, -429}, +{ -329, -329, -329, -329, -329}}, +/* @.AC..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -679, -679, -679, -679, -679}, +{ -559, -559, -559, -559, -559}, +{ -729, -729, -729, -729, -729}, +{ -189, -189, -189, -189, -189}}, +/* @.AG..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -939, -939, -939, -939, -939}, +{ -249, -249, -249, -249, -249}, +{ -939, -939, -939, -939, -939}, +{ -329, -329, -329, -329, -329}}, +/* @.AU..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -639, -639, -639, -639, -639}, +{ -229, -229, -229, -229, -229}, +{ -729, -729, -729, -729, -729}, +{ -190, -190, -190, -190, -190}}}, +/* @.C@..UA */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -449, -449, -449, -449, -449}, +{ -479, -479, -479, -479, -479}, +{ -429, -429, -429, -429, -429}, +{ -329, -329, -329, -329, -329}}, +/* @.CC..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -679, -679, -679, -679, -679}, +{ -559, -559, -559, -559, -559}, +{ -729, -729, -729, -729, -729}, +{ -189, -189, -189, -189, -189}}, +/* @.CG..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -939, -939, -939, -939, -939}, +{ -249, -249, -249, -249, -249}, +{ -939, -939, -939, -939, -939}, +{ -329, -329, -329, -329, -329}}, +/* @.CU..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -639, -639, -639, -639, -639}, +{ -229, -229, -229, -229, -229}, +{ -729, -729, -729, -729, -729}, +{ -190, -190, -190, -190, -190}}}, +/* @.G@..UA */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -449, -449, -449, -449, -449}, +{ -479, -479, -479, -479, -479}, +{ -429, -429, -429, -429, -429}, +{ -329, -329, -329, -329, -329}}, +/* @.GC..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -679, -679, -679, -679, -679}, +{ -559, -559, -559, -559, -559}, +{ -729, -729, -729, -729, -729}, +{ -189, -189, -189, -189, -189}}, +/* @.GG..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -939, -939, -939, -939, -939}, +{ -249, -249, -249, -249, -249}, +{ -939, -939, -939, -939, -939}, +{ -329, -329, -329, -329, -329}}, +/* @.GU..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -639, -639, -639, -639, -639}, +{ -229, -229, -229, -229, -229}, +{ -729, -729, -729, -729, -729}, +{ -190, -190, -190, -190, -190}}}, +/* @.U@..UA */ +{{{ DEF, DEF, DEF, DEF, DEF}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -449, -449, -449, -449, -449}, +{ -479, -479, -479, -479, -479}, +{ -429, -429, -429, -429, -429}, +{ -329, -329, -329, -329, -329}}, +/* @.UC..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -679, -679, -679, -679, -679}, +{ -559, -559, -559, -559, -559}, +{ -729, -729, -729, -729, -729}, +{ -189, -189, -189, -189, -189}}, +/* @.UG..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -939, -939, -939, -939, -939}, +{ -249, -249, -249, -249, -249}, +{ -939, -939, -939, -939, -939}, +{ -329, -329, -329, -329, -329}}, +/* @.UU..UA */ +{{ DEF, DEF, DEF, DEF, DEF}, +{ -639, -639, -639, -639, -639}, +{ -229, -229, -229, -229, -229}, +{ -729, -729, -729, -729, -729}, +{ -190, -190, -190, -190, -190}}}}, +/* @.@@.. @ */ +{{{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@A.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@C.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@G.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.@U.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}}, +/* @.A@.. @ */ +{{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AA.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AC.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AG.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.AU.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}}, +/* @.C@.. @ */ +{{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CA.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CC.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CG.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.CU.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}}, +/* @.G@.. @ */ +{{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GA.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GC.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GG.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.GU.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}}, +/* @.U@.. @ */ +{{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UA.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UC.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UG.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}, +/* @.UU.. @ */ +{{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}, +{ -100, -100, -100, -100, -100}}}}}}; + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/inverse.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/inverse.c new file mode 100755 index 00000000..01c6ae97 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/inverse.c @@ -0,0 +1,529 @@ +/* + search for sequences that + fold into a given target structure + + c Ivo Hofacker + Vienna RNA package +*/ +/* Last changed Time-stamp: <2002-11-06 17:09:27 ivo> */ + +#define TDIST 0 /* use tree distance */ +#define PF 1 /* include support for partiton function */ + +#include +#include +#include +#include +#include +#if PF +#include "part_func.h" +#endif +#include "fold.h" +#if TDIST +#include "dist_vars.h" +#include "treedist.h" +#include "RNAstruct.h" +#endif +#include "utils.h" +#include "fold_vars.h" +#include "pair_mat.h" +/*@unused@*/ +static char rcsid[] = "$Id: inverse.c,v 1.11 2002/11/07 11:48:07 ivo Exp $"; +#define PUBLIC +#define PRIVATE static +PRIVATE double adaptive_walk(char *start, const char *target); +PRIVATE void shuffle(int *list, int len); +PRIVATE void make_start(char* start, const char *structure); +PRIVATE void make_ptable(const char *structure, int *table); +PRIVATE void make_pairset(void); +PRIVATE double mfe_cost(const char *, char*, const char *); +PRIVATE double pf_cost(const char *, char *, const char *); +PRIVATE char *aux_struct(const char* structure ); + +/* for backward compatibility, make sure symbolset can hold 20 characters */ +PRIVATE char default_alpha[21] = "AUGC"; +PUBLIC char *symbolset = default_alpha; +PUBLIC int give_up = 0; +PUBLIC float final_cost = 0; /* when to stop inverse_pf_fold */ +PUBLIC int inv_verbose=0; /* print out substructure on which inverse_fold() fails */ + +PRIVATE char pairset[2*MAXALPHA+1]; +PRIVATE int base, npairs; +PRIVATE int nc2; + +/*-------------------------------------------------------------------------*/ +PRIVATE int fold_type; +#if TDIST +PRIVATE Tree *T0; +#endif +PRIVATE double cost2; + +PRIVATE double adaptive_walk(char *start, const char *target) +{ +#ifdef DUMMY + printf("%s\n%s %c\n", start, target, backtrack_type ); + return 0.; +#endif + int i,j,p,tt,w1,w2, n_pos, len, flag; + long walk_len; + char *string, *string2, *cstring, *structure, *struct2; + int *mut_pos_list, mut_sym_list[MAXALPHA+1], mut_pair_list[2*MAXALPHA+1]; + int *w1_list, *w2_list, mut_position, symbol, bp; + int *target_table, *test_table; + char cont; + double cost, current_cost, ccost2; + double (*cost_function)(const char *, char *, const char *); + + len = strlen(start); + if (strlen(target)!=len) { + fprintf(stderr, "%s\n%s\n", start, target); + nrerror("adaptive_walk: start and target have unequal length"); + } + string = (char *) space(sizeof(char)*(len+1)); + cstring = (char *) space(sizeof(char)*(len+1)); + string2 = (char *) space(sizeof(char)*(len+1)); + structure = (char *) space(sizeof(char)*(len+1)); + struct2 = (char *) space(sizeof(char)*(len+1)); + mut_pos_list = (int *) space(sizeof(int)*len); + w1_list = (int *) space(sizeof(int)*len); + w2_list = (int *) space(sizeof(int)*len); + target_table = (int *) space(sizeof(int)*len); + test_table = (int *) space(sizeof(int)*len); + + make_ptable(target, target_table); + + for (i=0; i0) do { + cont=0; + + if (fold_type==0) { /* min free energy fold */ + make_ptable(structure, test_table); + for (j=w1=w2=flag=0; j0)) + if ((target_table[j-1]1) if (w2_list[w2-2]==w2_list[w2-1]) w2--; + + flag = 1; + } else { + if (flag==1) if ((tt0) cont=1; + break; + } + } + if ((current_cost>0)&&(cont==0)&&(string2[0])) { + /* no mutation that decreased cost was found, + but the the sequence in string2 decreases cost2 while keeping + cost constant */ + strcpy(cstring, string2); + strcpy(structure, struct2); + nc2++; cont=1; + } + } while (cont); + + for (i=0; i0)&&(give_up)) goto adios + +PUBLIC float inverse_fold(char *start, char *structure) +{ + int i, j, jj, len, o; + int *pt; + char *string, *wstring, *wstruct, *aux; + double dist=0; + + nc2 = j = o = fold_type = 0; + + len = strlen(structure); + if (strlen(start)!=len) { + fprintf(stderr, "%s\n%s\n", start, structure); + nrerror("inverse_fold: start and structure have unequal length"); + } + string = (char *) space(len+1); + wstring = (char *) space(len+1); + wstruct = (char *) space(len+1); + pt = (int *) space(sizeof(int)*(len+1)); + pt[len] = len+1; + + aux = aux_struct(structure); + strcpy(string, start); + make_pairset(); + make_start(string, structure); + + make_ptable(structure, pt); + + while (j=0)&&(aux[i]=='.')) i--; + if (pt[j]!=i) { + backtrack_type = (o==0)? 'F' : 'M'; + if (j-jj>8) { WALK((i+1),(jj)); } + WALK((i+1), (j-1)); + while ((i>=0) &&(aux[i]==']')) { + i=pt[i]-1; + while ((i>=0)&&(aux[i]=='.')) i--; + WALK((i+1), (j-1)); + } + } + } + } + adios: + backtrack_type='F'; + if ((dist>0)&&(inv_verbose)) printf("%s\n%s\n", wstring, wstruct); + /*if ((dist==0)||(give_up==0))*/ strcpy(start, string); + free(wstring); free(wstruct); + free(string); free(aux); + free(pt); +/* if (dist>0) printf("%3d \n", nc2); */ + return dist; +} + +/*-------------------------------------------------------------------------*/ + +PUBLIC float inverse_pf_fold(char *start, char *target) +{ + double dist; + int dang; + + dang=dangles; + if (dangles!=0) dangles=2; + + update_fold_params(); /* make sure there is a valid pair matrix */ + make_pairset(); + make_start(start, target); + fold_type=1; + do_backtrack = 0; + dist = adaptive_walk(start, target); + dangles=dang; + return (dist+final_cost); +} + +/*-------------------------------------------------------------------------*/ + +PRIVATE void make_start(char* start, const char *structure) +{ + int i,j,k,l,r,length; + int *table, *S, sym[MAXALPHA], ss; + + length=strlen(start); + table = (int *) space(sizeof(int)*length); + S = (int *) space(sizeof(int)*length); + + make_ptable(structure, table); + for (i=0; i1_U5ztyIR(EhMH zDJS@*KYU8EnR^>9+3J19J-+pev7sgFrnY{OT(LEjmDTfnZ>jntbK5>^Eb({DOhO;N zyCkbPYf07(StZ@*V(S;FjemeLSqI$r_dq)FoWCOh?Cj6#*`FOwS`S$#9z`gt=Z}Db zs_c%G^{eOQ1ozDir`$g`oOCOSZ1Q(pj_Um351zq$`flN*6PhUIzpdDbyD-Y~4?~t! zkQM%ih*A2H?99Kdog&O+hmZM#FOB_6N2t>{;~n?H8SnM*m$JwFOV3{awvK`}BV5pF zghOoxlxg|{h5(vD=v$aogpn`I_uum24(J*F@UEnGQIW@!THr2Y-LXqB;q0W<5(ri& zt@dYjg(h$XIyMOjQF(vI9YRM$5ITyJR`=`;zb$lx-_8jiAj%J#D;2tq>CO@V0ZxEd z*-5300li3}^Ay^z(6baeE&Yh#{2igBG(Xh_l_q!He72`Y_V5$26C+{YszhPu|h)(Z6;7&rHcj6^C+=J0*0TOMO z&V}*e&2}eYXYM&D`^*{d;OwNtwjOWW&q2Xaq2y?BlE>fClvJ4;{#tl`6hr`wtMCrV 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.c new file mode 100755 index 00000000..1518bb35 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.c @@ -0,0 +1,411 @@ +/* + $Log: list.c,v $ + Revision 1.5 2003/07/14 13:36:58 ivo + use space() instead of malloc + + Revision 1.4 2000/10/10 08:53:52 ivo + include dmalloc.h header if DMALLOC defined + + Revision 1.4 2000/10/10 08:04:34 ivo + include dmalloc header id DMALLOC defined + + Revision 1.3 1998/03/30 14:24:51 ivo + use RNA package utils.h + + Revision 1.2 1997/10/09 19:01:50 steve + *** empty log message *** + + Revision 1.1 1997/08/04 21:05:32 walter + Initial revision + +*/ +/* + (C) 1991 Kendall Bennett. +*/ + +#include +#include +#include "utils.h" +#include "list.h" + +/*@unused@*/ +static char rcsid[] = "$Id: list.c,v 1.5 2003/07/14 13:36:58 ivo Exp $"; + +#define PUBLIC +PUBLIC void * +lst_newnode (int size) +/**************************************************************************** +* +* Function: lst_newnode +* Parameters: size - Amount of memory to allocate for node +* Returns: Pointer to the allocated node's user space. +* +* Description: Allocates the memory required for a node, adding a small +* header at the start of the node. We return a reference to +* the user space of the node, as if it had been allocated via +* malloc(). +* +****************************************************************************/ +{ + LST_BUCKET *node; + + node = (LST_BUCKET *) space (size + sizeof (LST_BUCKET)); + + return LST_USERSPACE (node); /* Return pointer to user space */ +} + +PUBLIC void +lst_freenode (void *node) +/**************************************************************************** +* +* Function: lst_freenode +* Parameters: node - Node to free. +* +* Description: Frees a node previously allocated with lst_newnode(). +* +****************************************************************************/ +{ + free (LST_HEADER (node)); +} + +PUBLIC LIST * +lst_init (void) +/**************************************************************************** +* +* Function: lst_init +* Returns: Pointer to a newly created list. +* +* Description: Initialises a list and returns a pointer to it. +* +****************************************************************************/ +{ + LIST *l; + + if ((l = (LIST *) space (sizeof (LIST))) != NULL) + { + l->count = 0; + l->head = &(l->hz[0]); + l->z = &(l->hz[1]); + l->head->next = l->z->next = l->z; + } + + return l; +} + +PUBLIC void +lst_kill (LIST * l, void (*freeNode) (void *node)) +/**************************************************************************** +* +* Function: lst_kill +* Parameters: l - List to kill +* freeNode - Pointer to user routine to free a node +* +* Description: Kills the list l, by deleting all of the elements contained +* within the list one by one and then deleting the list +* itself. Note that we call the user supplied routine +* (*freeNode)() to free each list node. This allows the user +* program to perform any extra processing needed to kill each +* node (if each node contains pointers to other items on the +* heap for example). If no extra processing is required, just +* pass the address of lst_freenode(), ie: +* +* lst_kill(myList,lst_freenode); +* +****************************************************************************/ +{ + LST_BUCKET *n, *p; + + n = l->head->next; + while (n != l->z) + { /* Free all nodes in list */ + p = n; + n = n->next; + (*freeNode) (LST_USERSPACE (p)); + } + free (l); /* Free the list itself */ +} + +PUBLIC void +lst_insertafter (LIST * l, void *node, void *after) +/**************************************************************************** +* +* Function: lst_insertafter +* Parameters: l - List to insert node into +* node - Pointer to user space of node to insert +* after - Pointer to user space of node to insert node after +* +* Description: Inserts a new node into the list after the node 'after'. To +* insert a new node at the beginning of the list, user the +* macro LST_HEAD in place of 'after'. ie: +* +* lst_insertafter(mylist,node,LST_HEAD(mylist)); +* +****************************************************************************/ +{ + LST_BUCKET *n = LST_HEADER (node), *a = LST_HEADER (after); + + n->next = a->next; + a->next = n; + l->count++; +} + +PUBLIC void * +lst_deletenext (LIST * l, void *node) +/**************************************************************************** +* +* Function: lst_deletenext +* Parameters: l - List to delete node from. +* node - Node to delete the next node from +* Returns: Pointer to the deleted node's userspace. +* +* Description: Removes the node AFTER 'node' from the list l. +* +****************************************************************************/ +{ + LST_BUCKET *n = LST_HEADER (node); + + node = LST_USERSPACE (n->next); + n->next = n->next->next; + l->count--; + return node; +} + +PUBLIC void * +lst_first (LIST * l) +/**************************************************************************** +* +* Function: lst_first +* Parameters: l - List to obtain first node from +* Returns: Pointer to first node in list, NULL if list is empty. +* +* Description: Returns a pointer to the user space of the first node in +* the list. If the list is empty, we return NULL. +* +****************************************************************************/ +{ + LST_BUCKET *n; + + n = l->head->next; + return (n == l->z ? NULL : LST_USERSPACE (n)); +} + +PUBLIC void * +lst_next (void *prev) +/**************************************************************************** +* +* Function: lst_next +* Parameters: prev - Previous node in list to obtain next node from +* Returns: Pointer to the next node in the list, NULL at end of list. +* +* Description: Returns a pointer to the user space of the next node in the +* list given a pointer to the user space of the previous node. +* If we have reached the end of the list, we return NULL. The +* end of the list is detected when the next pointer of a node +* points back to itself, as does the dummy last node's next +* pointer. This enables us to detect the end of the list +* without needed access to the list data structure itself. +* +* NOTE: We do no checking to ensure that 'prev' is NOT a +* NULL pointer. +* +****************************************************************************/ +{ + LST_BUCKET *n = LST_HEADER (prev); + + n = n->next; + return (n == n->next ? NULL : LST_USERSPACE (n)); +} + +/* Static globals required by merge() */ + +static LST_BUCKET *z; +static int (*cmp) (void *, void *); + +static LST_BUCKET * +merge (LST_BUCKET * a, LST_BUCKET * b, LST_BUCKET ** end) +/**************************************************************************** +* +* Function: merge +* Parameters: a,b - Sublist's to merge +* Returns: Pointer to the merged sublists. +* +* Description: Merges two sorted lists of nodes together into a single +* sorted list. +* +****************************************************************************/ +{ + LST_BUCKET *c; + + /* Go through the lists, merging them together in sorted order */ + + c = z; + while (a != z && b != z) + { + if ((*cmp) (LST_USERSPACE (a), LST_USERSPACE (b)) <= 0) + { + c->next = a; + c = a; + a = a->next; + } + else + { + c->next = b; + c = b; + b = b->next; + } + }; + + /* If one of the lists is not exhausted, then re-attach it to the end + * of the newly merged list + */ + + if (a != z) + c->next = a; + if (b != z) + c->next = b; + + /* Set *end to point to the end of the newly merged list */ + + while (c->next != z) + c = c->next; + *end = c; + + /* Determine the start of the merged lists, and reset z to point to + * itself + */ + + c = z->next; + z->next = z; + return c; +} + +PUBLIC void +lst_mergesort (LIST * l, int (*cmp_func) (void *, void *)) +/**************************************************************************** +* +* Function: lst_mergesort +* Parameters: l - List to merge sort +* cmp_func - Function to compare two user spaces +* +* Description: Mergesort's all the nodes in the list. 'cmp' must point to +* a comparison function that can compare the user spaces of +* two different nodes. 'cmp' should work the same as +* strcmp(), in terms of the values it returns. +* +****************************************************************************/ +{ + int i, N; + LST_BUCKET *a, *b; /* Pointers to sublists to merge */ + LST_BUCKET *c; /* Pointer to end of sorted sublists */ + LST_BUCKET *head; /* Pointer to dummy head node for list */ + LST_BUCKET *todo; /* Pointer to sublists yet to be sorted */ + LST_BUCKET *t; /* Temporary */ + + /* Set up globals required by merge() and pointer to head */ + + z = l->z; + cmp = cmp_func; + head = l->head; + + for (N = 1, a = z; a != head->next; N = N + N) + { + todo = head->next; + c = head; + while (todo != z) + { + + /* Build first sublist to be merged, and splice from main list + */ + + a = t = todo; + for (i = 1; i < N; i++) + t = t->next; + b = t->next; + t->next = z; + t = b; + + /* Build second sublist to be merged and splice from main list + */ + + for (i = 1; i < N; i++) + t = t->next; + todo = t->next; + t->next = z; + + /* Merge the two sublists created, and set 'c' to point to the + * end of the newly merged sublists. + */ + + c->next = merge (a, b, &t); + c = t; + } + } +} + +#ifdef LIST_TEST + +/*---------------------------------------------------------------*/ +/*---------------------------------------------------------------*/ + +/* Simple program to test the list routines */ + +typedef struct +{ + char name[40]; + int age; +} +REC; + +/*---------------------------------------------------------------*/ + +int +my_cmp (REC * r1, REC * r2) +{ + return strcmp (r1->name, r2->name); +} + +/*---------------------------------------------------------------*/ + +void +main (void) +{ + LIST *list; + int done = 0; + REC *rec; + char line[80]; + + list = lst_init (); + + printf ("Type a list of names and ages. Empty line quits\n\n"); + + while (!done) + { + rec = lst_newnode (sizeof (REC)); + gets (line); + if ((done = (line[0] == '\0')) != 1) + { + strcpy (rec->name, line); + gets (line); + rec->age = atoi (line); + lst_insertafter (list, rec, LST_HEAD (list)); + } + }; + + printf ("\nThe list you typed in was:\n\n"); + + for (rec = lst_first (list); rec; rec = lst_next (rec)) + printf ("Name: %s, Age: %d\n", rec->name, rec->age); + + printf ("\nSorting the list...\n\n"); + + lst_mergesort (list, my_cmp); + + for (rec = lst_first (list); rec; rec = lst_next (rec)) + printf ("Name: %s, Age: %d\n", rec->name, rec->age); + + lst_kill (list, lst_freenode); +} + +/*---------------------------------------------------------------*/ + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.h b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.h new file mode 100755 index 00000000..31fd3cef --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.h @@ -0,0 +1,65 @@ +/* + $Log: list.h,v $ + Revision 1.2 2000/10/10 08:50:01 ivo + some annotation for lclint + + Revision 1.1 1997/08/04 21:05:32 walter + Initial revision + +*/ + +#ifndef __LIST_H +#define __LIST_H + +/*---------------------- Macros and type definitions ----------------------*/ + +typedef struct LST_BUCKET { + struct LST_BUCKET *next; +} +LST_BUCKET; + +typedef struct { + int count; /* Number of elements currently in list */ + LST_BUCKET *head; /* Pointer to head element of list */ + LST_BUCKET *z; /* Pointer to last node of list */ + LST_BUCKET hz[2]; /* Space for head and z nodes */ +} +LIST; + +/* Return a pointer to the user space given the address of the header of + * a node. + */ + +#define LST_USERSPACE(h) ((void*)((LST_BUCKET*)(h) + 1)) + +/* Return a pointer to the header of a node, given the address of the + * user space. + */ + +#define LST_HEADER(n) ((LST_BUCKET*)(n) - 1) + +/* Return a pointer to the user space of the list's head node. This user + * space does not actually exist, but it is useful to be able to address + * it to enable insertion at the start of the list. + */ + +#define LST_HEAD(l) LST_USERSPACE((l)->head) + +/* Determine if a list is empty + */ + +#define LST_EMPTY(l) ((l)->count == 0) + +/*-------------------------- Function Prototypes --------------------------*/ + +/*@only@*//*@out@*/ void *lst_newnode (int size); +void lst_freenode (/*@only@*/ void *node); +/*@only@*//*@out@*/ LIST *lst_init (void); +void lst_kill (LIST * l, void (*freeNode) ()); +void lst_insertafter (LIST * l, /*@keep@*/ void *node, void *after); +void *lst_deletenext (/*@only@*/ LIST * l, void *node); +/*@dependent@*/ void *lst_first (LIST * l); +/*@dependent@*/ void *lst_next (void *prev); +void lst_mergesort (LIST * l, int (*cmp_func) ()); + +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/list.o new file mode 100755 index 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/naview.c new file mode 100755 index 00000000..3915d94e --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/naview.c @@ -0,0 +1,1149 @@ +/* +* NAVIEW -- A program to make a modified radial drawing of an RNA +* secondary structure. +* +* Copyright (c) 1988 Robert E. Bruccoleri +* Copying of this software, in whole or in part, is permitted +* provided that the copies are not made for commercial purposes, +* appropriate credit for the use of the software is given, this +* copyright notice appears, and notice is given that the copying +* is by permission of Robert E. Bruccoleri. Any other copying +* requires specific permission. +* +* See R. Bruccoleri and G. Heinrich, Computer Applications in the +* Biosciences, 4, 167-173 (1988) for a full description. +* +* In November 1997, Michael Zuker made a number of changes to bring +* naview up to modern standards. All functions defined in naview are +* now declared before main() with arguments and argument types. +* When functions are defined, their argument types are declared +* with the function and these definitions are removed after the '{'. +* The 'void' declaration was used as necessary for functions. +* +* The troublesome na_scanf function was deleted and replaced by +* scanf. Finally, there is now no default for the minimum separation +* of bases. A floating point number must be entered. However, as +* before an entry < 0 will be moved up to 0 and an entry > 0.5 +* will be reduced to 0.5. +* +* Adapted for use as a subroutine in the Vienna RNA Package +* by Ivo Hofacker, May 1998: +* deleted output routines, replaced main() by naview_xy_coordinates(), +* which fills the X and Y arrays used by PS_rna_plot() etc. +* added ansi prototypes and fixed memory leaks. +*/ + +#include +#include +#include +#include + +#include "utils.h" + +typedef int LOGICAL; +#define logical LOGICAL + +#define true 1 +#define false 0 +#define FATAL_ERROR 1 +#define SUCCESS 0 + +#define type_alloc(type) (type *) space(sizeof(type)) + +#define struct_alloc(structure_name) type_alloc(struct structure_name) + +#define add_double_list(head,tail,newp) {\ + (newp)->next = (newp)->prev = NULL; \ + if ((head) == NULL) (head) = (tail) = (newp); \ + else { \ + (tail)->next = (newp); \ + (newp)->prev = (tail); \ + (tail) = (newp); \ + } \ + } + +static double pi = 3.141592653589793; +static double anum = 9999.0; + + +/* +* Function data type definitions +*/ + +#define minf2(x1, x2) ((x1)<(x2))?(x1):(x2) +#define maxf2(x1, x2) ((x1)>(x2))?(x1):(x2) + +static struct base { + int mate; + double x,y; + logical extracted; + struct region *region; +} *bases; + +struct region { + int start1,end1,start2,end2; +}; + +struct loop { + int nconnection; + struct connection **connections; + int number; + int depth; + logical mark; + double x,y,radius; +}; + +struct connection { + struct loop *loop; + struct region *region; + int start,end; /* Start and end form the 1st base pair of the region. */ + double xrad,yrad,angle; + logical extruded; /* True if segment between this connection and + the next must be extruded out of the circle */ + logical broken; /* True if the extruded segment must be drawn long. */ +}; + +static int nbase, nregion, loop_count; + +static struct loop *root, *loops; + +static struct region *regions; + +static struct loop *construct_loop(int ibase); + +struct radloop { + double radius; + int loopnumber; + struct radloop *next, *prev; +}; + +static struct radloop *rlphead; + +static double lencut; + +static logical debug = false; + +static void read_in_bases(short *pair_table); +static void find_regions(void); +static void dump_loops(void); +static void find_central_loop(void); +static void determine_depths(void); +static void traverse_loop(struct loop *lp,struct connection *anchor_connection); +static void determine_radius(struct loop *lp,double lencut); +static void generate_region(struct connection *cp); +static void construct_extruded_segment(struct connection *cp,struct connection *cpnext); +static void find_center_for_arc(int n,double b,double *hp,double *thetap); +static int depth(struct loop *lp); + +static logical connected_connection(struct connection *cp, struct connection *cpnext); +static int find_ic_middle(int icstart, int icend, struct connection *anchor_connection, struct connection *acp, struct loop *lp); + + +int naview_xy_coordinates(short *pair_table, float *X, float *Y) { + int i; + + nbase = pair_table[0]; /* length */ + bases = (struct base *) space(sizeof(struct base)*(nbase+1)); + regions = (struct region *) space(sizeof(struct region)*(nbase+1)); + read_in_bases(pair_table); + lencut = 0.5; + rlphead = NULL; + find_regions(); + loop_count = 0; + loops = (struct loop *) space(sizeof(struct loop)*(nbase+1)); + construct_loop(0); + find_central_loop(); + if (debug) dump_loops(); + + traverse_loop(root,NULL); + for (i=0; ii) npairs++; + } + if (npairs==0) { /* must have at least 1 pair to avoid segfault */ + bases[1].mate=nbase; + bases[nbase].mate=1; + } +} + +static void find_regions(void) +/* +* Identifies the regions in the structure. +*/ + +{ + int i,mate,nb1; + logical *mark; + + nb1 = nbase + 1; + mark = (int *) space(sizeof(int)*nb1); + for (i = 0; i < nb1; i++) mark[i] = false; + nregion = 0; + for (i=0; i<=nbase; i++) { + if ( (mate = bases[i].mate) && !mark[i]) { + regions[nregion].start1 = i; + regions[nregion].end2 = mate; + mark[i] = true; + mark[mate] = true; + bases[i].region = bases[mate].region = ®ions[nregion]; + for (i++,mate--; + inconnection = 0; + retloop->connections = (struct connection **) space(sizeof(struct connection *)); + retloop->depth = 0; + retloop->number = loop_count; + retloop->radius = 0.0; + for (rlp = rlphead; rlp; rlp = rlp->next) + if (rlp->loopnumber == loop_count) retloop->radius = rlp->radius; + i = ibase; + do { + if ((mate = bases[i].mate) != 0) { + rp = bases[i].region; + if (!bases[rp->start1].extracted) { + if (i == rp->start1) { + bases[rp->start1].extracted = true; + bases[rp->end1].extracted = true; + bases[rp->start2].extracted = true; + bases[rp->end2].extracted = true; + lp = construct_loop(rp->end1 < nbase ? rp->end1+1 : 0); + } + else if (i == rp->start2){ + bases[rp->start2].extracted = true; + bases[rp->end2].extracted = true; + bases[rp->start1].extracted = true; + bases[rp->end1].extracted = true; + lp = construct_loop(rp->end2 < nbase ? rp->end2+1 : 0); + } + else { + fprintf(stderr, "naview: Error detected in construct_loop. i = %d not found in region table.\n",i); + exit(FATAL_ERROR); + } + retloop->connections = (struct connection **) + realloc(retloop->connections, + (++retloop->nconnection+1) * + sizeof(struct connection *)); + retloop->connections[retloop->nconnection-1] = cp = + struct_alloc(connection); + retloop->connections[retloop->nconnection] = NULL; + cp->loop = lp; + cp->region = rp; + if (i == rp->start1) { + cp->start = rp->start1; + cp->end = rp->end2; + } + else { + cp->start = rp->start2; + cp->end = rp->end1; + } + cp->extruded = false; + cp->broken = false; + lp->connections = (struct connection **) + realloc(lp->connections, + (++lp->nconnection+1) * + sizeof(struct connection *)); + lp->connections[lp->nconnection-1] = cp = + struct_alloc(connection); + lp->connections[lp->nconnection] = NULL; + cp->loop = retloop; + cp->region = rp; + if (i == rp->start1) { + cp->start = rp->start2; + cp->end = rp->end1; + } + else { + cp->start = rp->start1; + cp->end = rp->end2; + } + cp->extruded = false; + cp->broken = false; + } + i = mate; + } + if (++i > nbase) i = 0; + } + while (i != ibase); + return retloop; +} + +static void dump_loops(void) +/* +* Displays all the loops. +*/ + +{ + int il,ilp,irp; + struct loop *lp; + struct connection *cp,**cpp; + + printf("\nRoot loop is #%d\n",(root-loops)+1); + for (il=0; il < loop_count; il++) { + lp = &loops[il]; + printf("Loop %d has %d connections:\n",il+1,lp->nconnection); + for (cpp = lp->connections; (cp = *cpp); cpp++) { + ilp = (cp->loop - loops) + 1; + irp = (cp->region - regions) + 1; + printf(" Loop %d Region %d (%d-%d)\n", + ilp,irp,cp->start,cp->end); + } + } +} + +static void find_central_loop(void) +/* +* Find node of greatest branching that is deepest. +*/ + +{ + struct loop *lp; + int maxconn,maxdepth,i; + + determine_depths(); + maxconn = 0; + maxdepth = -1; + + for (i=0; inconnection > maxconn) { + maxdepth = lp->depth; + maxconn = lp->nconnection; + root = lp; + } + else if (lp->depth > maxdepth && lp->nconnection == maxconn) { + maxdepth = lp->depth; + root = lp; + } + } +} + +static void determine_depths(void) +/* +* Determine the depth of all loops. +*/ + +{ + struct loop *lp; + int i,j; + + for (i=0; idepth = depth(lp); + } +} + + +static int depth(struct loop *lp) +/* +* Determines the depth of loop, lp. Depth is defined as the minimum +* distance to a leaf loop where a leaf loop is one that has only one +* or no connections. +*/ + +{ + struct connection *cp,**cpp; + int count,ret,d; + + if (lp->nconnection <= 1) return 0; + if (lp->mark) return -1; + lp->mark = true; + count = 0; + ret = 0; + for (cpp=lp->connections; (cp = *cpp); cpp++) { + d = depth(cp->loop); + if (d >= 0) { + if (++count == 1) ret = d; + else if (ret > d) ret = d; + } + } + lp->mark = false; + return ret+1; +} + +static void traverse_loop(struct loop *lp, struct connection *anchor_connection) +/* +* This is the workhorse of the display program. The algorithm is +* recursive based on processing individual loops. Each base pairing +* region is displayed using the direction given by the circle diagram, +* and the connections between the regions is drawn by equally spaced +* points. The radius of the loop is set to minimize the square error +* for lengths between sequential bases in the loops. The "correct" +* length for base links is 1. If the least squares fitting of the +* radius results in loops being less than 1/2 unit apart, then that +* segment is extruded. +* +* The variable, anchor_connection, gives the connection to the loop +* processed in an previous level of recursion. +*/ + +{ + double xs,ys,xe,ye,xn,yn,angleinc,r; + double radius,xc,yc,xo,yo,astart,aend,a; + struct connection *cp,*cpnext,**cpp,*acp,*cpprev; + int i,j,n,ic; + double da,maxang; + int count,icstart,icend,icmiddle,icroot; + logical done,done_all_connections,rooted; + int sign; + double midx,midy,nrx,nry,mx,my,vx,vy,dotmv,nmidx,nmidy; + int icstart1,icup,icdown,icnext,direction; + double dan,dx,dy,rr; + double cpx,cpy,cpnextx,cpnexty,cnx,cny,rcn,rc,lnx,lny,rl,ac,acn,sx,sy,dcp; + int imaxloop; + + angleinc = 2 * pi / (nbase+1); + acp = NULL; + icroot = -1; + for (cpp=lp->connections, ic = 0; (cp = *cpp); cpp++, ic++) { + /* xs = cos(angleinc*cp->start); + ys = sin(angleinc*cp->start); + xe = cos(angleinc*cp->end); + ye = sin(angleinc*cp->end); */ + xs = -sin(angleinc*cp->start); + ys = cos(angleinc*cp->start); + xe = -sin(angleinc*cp->end); + ye = cos(angleinc*cp->end); + xn = ye-ys; + yn = xs-xe; + r = sqrt(xn*xn + yn*yn); + cp->xrad = xn/r; + cp->yrad = yn/r; + cp->angle = atan2(yn,xn); + if (cp->angle < 0.0) cp->angle += 2*pi; + if (anchor_connection != NULL && + anchor_connection->region == cp->region) { + acp = cp; + icroot = ic; + } + } + + set_radius: + determine_radius(lp,lencut); + radius = lp->radius; + if (anchor_connection == NULL) xc = yc = 0.0; + else { + xo = (bases[acp->start].x+bases[acp->end].x) / 2.0; + yo = (bases[acp->start].y+bases[acp->end].y) / 2.0; + xc = xo - radius * acp->xrad; + yc = yo - radius * acp->yrad; + } + + /* + * The construction of the connectors will proceed in blocks of + * connected connectors, where a connected connector pairs means + * two connectors that are forced out of the drawn circle because they + * are too close together in angle. + */ + + /* + * First, find the start of a block of connected connectors + */ + + if (icroot == -1) + icstart = 0; + else icstart = icroot; + cp = lp->connections[icstart]; + count = 0; + if (debug) printf("Now processing loop %d\n",lp->number); + done = false; + do { + j = icstart - 1; + if (j < 0) j = lp->nconnection - 1; + cpprev = lp->connections[j]; + if (!connected_connection(cpprev,cp)) { + done = true; + } + else { + icstart = j; + cp = cpprev; + } + if (++count > lp->nconnection) { + /* + * Here everything is connected. Break on maximum angular separation + * between connections. + */ + maxang = -1.0; + for (ic = 0; ic < lp->nconnection; ic++) { + j = ic + 1; + if (j >= lp->nconnection) j = 0; + cp = lp->connections[ic]; + cpnext = lp->connections[j]; + ac = cpnext->angle - cp->angle; + if (ac < 0.0) ac += 2*pi; + if (ac > maxang) { + maxang = ac; + imaxloop = ic; + } + } + icend = imaxloop; + icstart = imaxloop + 1; + if (icstart >= lp->nconnection) icstart = 0; + cp = lp->connections[icend]; + cp->broken = true; + done = true; + } + } while (!done); + done_all_connections = false; + icstart1 = icstart; + if (debug) printf("Icstart1 = %d\n",icstart1); + while (!done_all_connections) { + count = 0; + done = false; + icend = icstart; + rooted = false; + while (!done) { + cp = lp->connections[icend]; + if (icend == icroot) rooted = true; + j = icend + 1; + if (j >= lp->nconnection) { + j = 0; + } + cpnext = lp->connections[j]; + if (connected_connection(cp,cpnext)) { + if (++count >= lp->nconnection) break; + icend = j; + } + else { + done = true; + } + } + icmiddle = find_ic_middle(icstart,icend,anchor_connection,acp,lp); + ic = icup = icdown = icmiddle; + if (debug) + printf("IC start = %d middle = %d end = %d\n", + icstart,icmiddle,icend); + done = false; + direction = 0; + while (!done) { + if (direction < 0) { + ic = icup; + } + else if (direction == 0) { + ic = icmiddle; + } + else { + ic = icdown; + } + if (ic >= 0) { + cp = lp->connections[ic]; + if (anchor_connection == NULL || acp != cp) { + if (direction == 0) { + astart = cp->angle - asin(1.0/2.0/radius); + aend = cp->angle + asin(1.0/2.0/radius); + bases[cp->start].x = xc + radius*cos(astart); + bases[cp->start].y = yc + radius*sin(astart); + bases[cp->end].x = xc + radius*cos(aend); + bases[cp->end].y = yc + radius*sin(aend); + } + else if (direction < 0) { + j = ic + 1; + if (j >= lp->nconnection) j = 0; + cp = lp->connections[ic]; + cpnext = lp->connections[j]; + cpx = cp->xrad; + cpy = cp->yrad; + ac = (cp->angle + cpnext->angle) / 2.0; + if (cp->angle > cpnext->angle) ac -= pi; + cnx = cos(ac); + cny = sin(ac); + lnx = cny; + lny = -cnx; + da = cpnext->angle - cp->angle; + if (da < 0.0) da += 2*pi; + if (cp->extruded) { + if (da <= pi/2) rl = 2.0; + else rl = 1.5; + } + else { + rl = 1.0; + } + bases[cp->end].x = bases[cpnext->start].x + rl*lnx; + bases[cp->end].y = bases[cpnext->start].y + rl*lny; + bases[cp->start].x = bases[cp->end].x + cpy; + bases[cp->start].y = bases[cp->end].y - cpx; + } + else { + j = ic - 1; + if (j < 0) j = lp->nconnection - 1; + cp = lp->connections[j]; + cpnext = lp->connections[ic]; + cpnextx = cpnext->xrad; + cpnexty = cpnext->yrad; + ac = (cp->angle + cpnext->angle) / 2.0; + if (cp->angle > cpnext->angle) ac -= pi; + cnx = cos(ac); + cny = sin(ac); + lnx = -cny; + lny = cnx; + da = cpnext->angle - cp->angle; + if (da < 0.0) da += 2*pi; + if (cp->extruded) { + if (da <= pi/2) rl = 2.0; + else rl = 1.5; + } + else { + rl = 1.0; + } + bases[cpnext->start].x = bases[cp->end].x + rl*lnx; + bases[cpnext->start].y = bases[cp->end].y + rl*lny; + bases[cpnext->end].x = bases[cpnext->start].x - cpnexty; + bases[cpnext->end].y = bases[cpnext->start].y + cpnextx; + } + } + } + if (direction < 0) { + if (icdown == icend) { + icdown = -1; + } + else if (icdown >= 0) { + if (++icdown >= lp->nconnection) { + icdown = 0; + } + } + direction = 1; + } + else { + if (icup == icstart) icup = -1; + else if (icup >= 0) { + if (--icup < 0) { + icup = lp->nconnection - 1; + } + } + direction = -1; + } + done = icup == -1 && icdown == -1; + } + icnext = icend + 1; + if (icnext >= lp->nconnection) icnext = 0; + if (icend != icstart && (! (icstart == icstart1 && icnext == icstart1))) { + /* + * Move the bases just constructed (or the radius) so + * that the bisector of the end points is radius distance + * away from the loop center. + */ + cp = lp->connections[icstart]; + cpnext = lp->connections[icend]; + dx = bases[cpnext->end].x - bases[cp->start].x; + dy = bases[cpnext->end].y - bases[cp->start].y; + midx = bases[cp->start].x + dx/2.0; + midy = bases[cp->start].y + dy/2.0; + rr = sqrt(dx*dx + dy*dy); + mx = dx / rr; + my = dy / rr; + vx = xc - midx; + vy = yc - midy; + rr = sqrt(dx*dx + dy*dy); + vx /= rr; + vy /= rr; + dotmv = vx*mx + vy*my; + nrx = dotmv*mx - vx; + nry = dotmv*my - vy; + rr = sqrt(nrx*nrx + nry*nry); + nrx /= rr; + nry /= rr; + /* + * Determine which side of the bisector the center should be. + */ + dx = bases[cp->start].x - xc; + dy = bases[cp->start].y - yc; + ac = atan2(dy,dx); + if (ac < 0.0) ac += 2*pi; + dx = bases[cpnext->end].x - xc; + dy = bases[cpnext->end].y - yc; + acn = atan2(dy,dx); + if (acn < 0.0) acn += 2*pi; + if (acn < ac) acn += 2*pi; + if (acn - ac > pi) sign = -1; + else sign = 1; + nmidx = xc + sign*radius*nrx; + nmidy = yc + sign*radius*nry; + if (rooted) { + xc -= nmidx - midx; + yc -= nmidy - midy; + } + else { + for (ic=icstart; ; ++ic >= lp->nconnection ? (ic = 0) : 0) { + cp = lp->connections[ic]; + i = cp->start; + bases[i].x += nmidx - midx; + bases[i].y += nmidy - midy; + i = cp->end; + bases[i].x += nmidx - midx; + bases[i].y += nmidy - midy; + if (ic == icend) break; + } + } + } + icstart = icnext; + done_all_connections = icstart == icstart1; + } + for (ic=0; ic < lp->nconnection; ic++) { + cp = lp->connections[ic]; + j = ic + 1; + if (j >= lp->nconnection) j = 0; + cpnext = lp->connections[j]; + dx = bases[cp->end].x - xc; + dy = bases[cp->end].y - yc; + rc = sqrt(dx*dx + dy*dy); + ac = atan2(dy,dx); + if (ac < 0.0) ac += 2*pi; + dx = bases[cpnext->start].x - xc; + dy = bases[cpnext->start].y - yc; + rcn = sqrt(dx*dx + dy*dy); + acn = atan2(dy,dx); + if (acn < 0.0) acn += 2*pi; + if (acn < ac) acn += 2*pi; + dan = acn - ac; + dcp = cpnext->angle - cp->angle; + if (dcp <= 0.0) dcp += 2*pi; + if (fabs(dan-dcp) > pi) { + if (cp->extruded) { + fprintf(stderr, "Warning from traverse_loop. Loop %d has crossed regions\n", + lp->number); + } + else if ((cpnext->start - cp->end) != 1) { + cp->extruded = true; + goto set_radius; /* Forever shamed */ + } + } + if (cp->extruded) { + construct_extruded_segment(cp,cpnext); + } + else { + n = cpnext->start - cp->end; + if (n < 0) n += nbase + 1; + angleinc = dan / n; + for (j = 1; j < n; j++) { + i = cp->end + j; + if (i > nbase) i -= nbase + 1; + a = ac + j*angleinc; + rr = rc + (rcn-rc)*(a-ac)/dan; + bases[i].x = xc + rr*cos(a); + bases[i].y = yc + rr*sin(a); + } + } + } + for (ic=0; ic < lp->nconnection; ic++) { + if (icroot != ic) { + cp = lp->connections[ic]; + generate_region(cp); + traverse_loop(cp->loop,cp); + } + } + n = 0; + sx = 0.0; + sy = 0.0; + for (ic = 0; ic < lp->nconnection; ic++) { + j = ic + 1; + if (j >= lp->nconnection) j = 0; + cp = lp->connections[ic]; + cpnext = lp->connections[j]; + n += 2; + sx += bases[cp->start].x + bases[cp->end].x; + sy += bases[cp->start].y + bases[cp->end].y; + if (!cp->extruded) { + for (j = cp->end + 1; j != cpnext->start; j++) { + if (j > nbase) j -= nbase + 1; + n++; + sx += bases[j].x; + sy += bases[j].y; + } + } + } + lp->x = sx / n; + lp->y = sy / n; + + /* free connections (ih) */ + for (ic = 0; ic < lp->nconnection; ic++) + free(lp->connections[ic]); + free(lp->connections); +} + + +static void determine_radius(struct loop *lp,double lencut) +/* +* For the loop pointed to by lp, determine the radius of +* the loop that will ensure that each base around the loop will +* have a separation of at least lencut around the circle. +* If a segment joining two connectors will not support this separation, +* then the flag, extruded, will be set in the first of these +* two indicators. The radius is set in lp. +* +* The radius is selected by a least squares procedure where the sum of the +* squares of the deviations of length from the ideal value of 1 is used +* as the error function. +*/ + +{ + double mindit,ci,dt,sumn,sumd,radius,dit; + int i,j,end,start,imindit; + struct connection *cp,*cpnext; + static double rt2_2 = 0.7071068; + + do { + mindit = 1.0e10; + for (sumd=0.0, sumn=0.0, i=0; + i < lp->nconnection; + i++) { + cp = lp->connections[i]; + j = i + 1; + if (j >= lp->nconnection) j = 0; + cpnext = lp->connections[j]; + end = cp->end; + start = cpnext->start; + if (start < end) start += nbase + 1; + dt = cpnext->angle - cp->angle; + if (dt <= 0.0) dt += 2*pi; + if (!cp->extruded) + ci = start - end; + else { + if (dt <= pi/2) ci = 2.0; + else ci = 1.5; + } + sumn += dt * (1.0/ci + 1.0); + sumd += dt * dt / ci; + dit = dt/ci; + if (dit < mindit && !cp->extruded && ci > 1.0) { + mindit = dit; + imindit = i; + } + } + radius = sumn/sumd; + if (radius < rt2_2) radius = rt2_2; + if (mindit*radius < lencut) { + lp->connections[imindit]->extruded = true; + } + } while (mindit*radius < lencut); + if (lp->radius > 0.0) + radius = lp->radius; + else lp->radius = radius; +} + +static logical connected_connection(struct connection *cp, struct connection *cpnext) +/* +* Determines if the connections cp and cpnext are connected +*/ + +{ + + if (cp->extruded) { + return true; + } + else if (cp->end+1 == cpnext->start) { + return true; + } + else { + return false; + } +} + +static int find_ic_middle(int icstart, int icend, struct connection *anchor_connection, struct connection *acp, struct loop *lp) +/* +* Finds the middle of a set of connected connectors. This is normally +* the middle connection in the sequence except if one of the connections +* is the anchor, in which case that connection will be used. +*/ + +{ + int count,ret,ic,i; + logical done; + + count = 0; + ret = -1; + ic = icstart; + done = false; + while (!done) { + if (count++ > lp->nconnection * 2) { + printf("Infinite loop detected in find_ic_middle\n"); + exit(FATAL_ERROR); + } + if (anchor_connection != NULL && lp->connections[ic] == acp) { + ret = ic; + } + done = ic == icend; + if (++ic >= lp->nconnection) { + ic = 0; + } + } + if (ret == -1) { + for (i=1, ic=icstart; i<(count+1)/2; i++) { + if (++ic >= lp->nconnection) ic = 0; + } + ret = ic; + } + return ret; +} + +static void generate_region(struct connection *cp) +/* +* Generates the coordinates for the base pairing region of a connection +* given the position of the starting base pair. +*/ + +{ + int l,start,end,i,mate; + struct region *rp; + + rp = cp->region; + l = 0; + if (cp->start == rp->start1) { + start = rp->start1; + end = rp->end1; + } + else { + start = rp->start2; + end = rp->end2; + } + if (bases[cp->start].x > anum - 100.0 || + bases[cp->end].x > anum - 100.0) { + printf("Bad region passed to generate_region. Coordinates not defined.\n"); + exit(FATAL_ERROR); + } + for (i=start+1; i<=end; i++) { + l++; + bases[i].x = bases[cp->start].x + l*cp->xrad; + bases[i].y = bases[cp->start].y + l*cp->yrad; + mate = bases[i].mate; + bases[mate].x = bases[cp->end].x + l*cp->xrad; + bases[mate].y = bases[cp->end].y + l*cp->yrad; + } +} + +static void construct_circle_segment(int start, int end) +/* +* Draws the segment of residue between the bases numbered start +* through end, where start and end are presumed to be part of a base +* pairing region. They are drawn as a circle which has a chord given +* by the ends of two base pairing regions defined by the connections. +*/ + +{ + double dx,dy,rr,h,angleinc,midx,midy,xn,yn,nrx,nry,mx,my,a; + int l,j,i; + + dx = bases[end].x - bases[start].x; + dy = bases[end].y - bases[start].y; + rr = sqrt(dx*dx + dy*dy); + l = end - start; + if (l < 0) l += nbase + 1; + if (rr >= l) { + dx /= rr; + dy /= rr; + for (j = 1; j < l; j++) { + i = start + j; + if (i > nbase) i -= nbase + 1; + bases[i].x = bases[start].x + dx*(double)j/(double)l; + bases[i].y = bases[start].y + dy*(double)j/(double)l; + } + } + else { + find_center_for_arc(l-1,rr,&h,&angleinc); + dx /= rr; + dy /= rr; + midx = bases[start].x + dx*rr/2.0; + midy = bases[start].y + dy*rr/2.0; + xn = dy; + yn = -dx; + nrx = midx + h*xn; + nry = midy + h*yn; + mx = bases[start].x - nrx; + my = bases[start].y - nry; + rr = sqrt(mx*mx + my*my); + a = atan2(my,mx); + for (j = 1; j < l; j++) { + i = start + j; + if (i > nbase) i -= nbase + 1; + bases[i].x = nrx + rr*cos(a+j*angleinc); + bases[i].y = nry + rr*sin(a+j*angleinc); + } + } +} + +static void construct_extruded_segment(struct connection *cp, struct connection *cpnext) +/* +* Constructs the segment between cp and cpnext as a circle if possible. +* However, if the segment is too large, the lines are drawn between +* the two connecting regions, and bases are placed there until the +* connecting circle will fit. +*/ + +{ + double astart,aend1,aend2,aave,dx,dy,a1,a2,ac,rr,da,dac; + int start,end,n,nstart,nend; + logical collision; + + astart = cp->angle; + aend2 = aend1 = cpnext->angle; + if (aend2 < astart) aend2 += 2*pi; + aave = (astart + aend2) / 2.0; + start = cp->end; + end = cpnext->start; + n = end - start; + if (n < 0) n += nbase + 1; + da = cpnext->angle - cp->angle; + if (da < 0.0) { + da += 2*pi; + } + if (n == 2) construct_circle_segment(start,end); + else { + dx = bases[end].x - bases[start].x; + dy = bases[end].y - bases[start].y; + rr = sqrt(dx*dx + dy*dy); + dx /= rr; + dy /= rr; + if (rr >= 1.5 && da <= pi/2) { + nstart = start + 1; + if (nstart > nbase) nstart -= nbase + 1; + nend = end - 1; + if (nend < 0) nend += nbase + 1; + bases[nstart].x = bases[start].x + 0.5*dx; + bases[nstart].y = bases[start].y + 0.5*dy; + bases[nend].x = bases[end].x - 0.5*dx; + bases[nend].y = bases[end].y - 0.5*dy; + start = nstart; + end = nend; + } + do { + collision = false; + construct_circle_segment(start,end); + nstart = start + 1; + if (nstart > nbase) nstart -= nbase + 1; + dx = bases[nstart].x - bases[start].x; + dy = bases[nstart].y - bases[start].y; + a1 = atan2(dy,dx); + if (a1 < 0.0) a1 += 2*pi; + dac = a1 - astart; + if (dac < 0.0) dac += 2*pi; + if (dac > pi) collision = true; + nend = end - 1; + if (nend < 0) nend += nbase + 1; + dx = bases[nend].x - bases[end].x; + dy = bases[nend].y - bases[end].y; + a2 = atan2(dy,dx); + if (a2 < 0.0) a2 += 2*pi; + dac = aend1 - a2; + if (dac < 0.0) dac += 2*pi; + if (dac > pi) collision = true; + if (collision) { + ac = minf2(aave,astart + 0.5); + bases[nstart].x = bases[start].x + cos(ac); + bases[nstart].y = bases[start].y + sin(ac); + start = nstart; + ac = maxf2(aave,aend2 - 0.5); + bases[nend].x = bases[end].x + cos(ac); + bases[nend].y = bases[end].y + sin(ac); + end = nend; + n -= 2; + } + } while (collision && n > 1); + } +} + +static void find_center_for_arc(int n,double b,double *hp,double *thetap) +/* +* Given n points to be placed equidistantly and equiangularly on a +* polygon which has a chord of length, b, find the distance, h, from the +* midpoint of the chord for the center of polygon. Positive values +* mean the center is within the polygon and the chord, whereas +* negative values mean the center is outside the chord. Also, the +* radial angle for each polygon side is returned in theta. +* +* The procedure uses a bisection algorithm to find the correct +* value for the center. Two equations are solved, the angles +* around the center must add to 2*pi, and the sides of the polygon +* excluding the chord must have a length of 1. +*/ + +{ + double h,hhi,hlow,r,disc,theta,e,phi; + int iter; +#define maxiter 500 + + hhi = (n+1) / pi; + hlow = - hhi - b/(n+1.000001-b); /* changed to prevent div by zero if (ih) */ + if (b<1) hlow = 0; /* otherwise we might fail below (ih) */ + iter = 0; + do { + h = (hhi + hlow) / 2.0; + r = sqrt(h*h + b*b/4.0); + /* if (r<0.5) {r = 0.5; h = 0.5*sqrt(1-b*b);} */ + disc = 1.0 - 0.5/(r*r); + if (fabs(disc) > 1.0) { + fprintf(stderr, "Unexpected large magnitude discriminant = %g %g\n", disc,r); + exit(FATAL_ERROR); + } + theta = acos(disc); + /* theta = 2*acos(sqrt(1-1/(4*r*r))); */ + phi = acos(h/r); + e = theta * (n+1) + 2*phi - 2*pi; + if (e > 0.0) { + hlow = h; + } + else { + hhi = h; + } + } while (fabs(e) > 0.0001 && ++iter < maxiter); + if (iter >= maxiter) { + fprintf(stderr, "Iteration failed in find_center_for_arc\n"); + h = 0.0; + theta = 0.0; + } + *hp = h; + *thetap = theta; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/naview.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/naview.o new file mode 100755 index 0000000000000000000000000000000000000000..a8f443b46564b70033d22bb554bacdcfb6c67276 GIT binary patch literal 58328 zcmeIbdwf*Y)i-`lPQW7|Gu#vva4#+FSTA|k+Iy{YcJ@hX+xPkXKF=TT z`H(qlfA`vJt-bcz*E5`1pPN4?#WW4ROyg3+O)+X1cYfEUX9{wrG0ZsE$XSw8oKuuj zShP5_;cs^G49rTbO;3Hw1|k%Bp<`F5CG};2ioDRsL!sm#Oy{>u-<@;dG$fDVhb&8( zd5O7pR$I=2xdSl^Qkgl41^(kbwuX|6{Gp96*7wbxXE&S-B~vi(czd!cJ+-1@YsJ=3 zWFLtDy-lH(KKq31)P5V=5~=CF<`q!6{A5+XKu)p&?AwoA$+f!&Z|v}G3_)J@`@ZHH zxaVZAvV9wO19c$SZ!p}9yhv^zg0kWNx2nJy3f~f$7Wt$FUc_>gdQx zUYwWMpO;*3x6Cm&>`w_rJ_+r5$I3~ZCVVhIav|3IsVPt@l-MJ%yvSK#3?z5WO9bCK zm6x1r=O?oA6P0%8Kp;##yyYY(=Or6;ojpnC z1$l`%y3R9QeRDuxwyF{s&6_~7)Y!+PF*zo^W8bu~sC*}W_!bg(_9#y70Re^!S|8k15+VT=#VnA=0VK%NxE*ZQN#C2?Zu^}8vmf2bF zDz7i8{4OE*5<&^I}EU`N}uIey=^Hs2#{ z9|^vkB@o0pi4JrU^uz>&(@_gMWPaq`%UTBRC<^U*(^?$5@o%?*kWf-INY2QwDt!He z8GiVz&#+JWN`s^P@L4|!=zhWUH79-k{g9WB)YAR%_w-3$$*z;Wg>53g*0*U`s$rbW z@r`;#u+>)h#y#V^DG4edU7Efo=Sj5rq;L6$x!He*+pACx;B{97r3JHFQZEcj=fj`QOXY*mpV2q-wkq}0Xu@yO0>HqAMNg!pW$EoKIyZLNz zPsg4cKmQ2szAXdblTCwrDH_n9l$VII&=jC(sVEKi*FgRrxWk`lmV=N+XTjg{LqP8X zGr?W{L!iG6H17q?`+T>2BL$82Lr%Ym>F|-Co+*s;%Wi<0{jwD3gDlhm?g)U?U4o@0 z*96N1QUY=%|EPmNp}eKoI+!4Tmb8HxkfuuC@-B2m5Gs7(%6mO0t`Y2{J9daLgXpUPhSb2pb%RNasczA68Q5Ufjj(_yae6uMUh)8YAw13 z=qvHHoc<+_Z6cznUsY`Fs%J%xgj$B&o`YTMEephM7A^qU`ROH~38Dr=K}d&Oh;%Se z1VBj;4eS>j4SmfoLqIYJBOn(HhFt&Jgtzx4g;#^-iC{~u*?#DAXBY-iyTw4f6T(rB z!0uSQRasBm_%|H+q@4WZ5^M({Gn9BT{cgw!C4QBDC*BVF zIbBLC-JVW7P$@qI(NefCg?kC~Qa{A^LKv8qzX0{GGeR4l6wLw4kpp7VZ5GMAWRV@pE`Y_<&k+T8<|pnK?Umdt z8U@@+4o++qZH7+Xcsq%}hR#nG*umsbY~P9?jf{D}fmERE&XidQiGeXsM3rHjn2{$& z3d1-$156!(Hr+5Ihby@}MOpIW0Nn<5=CiWF}OtEqjme^4-bCfuY;- zk^@0X|9Kh7c@W2?muJ9Aq_>&WP z44VW_$Oi_zKqgEA#{(Vvf{7inSmNXCH`ZSX-asBKdIsEsNtv6|@jKt9c38G?#3#?m zi|ox$6sG(06YtMYPTZZJ`1DxI$GBq6PXgNT(~f{h&qD0&kX z*b{-I$pi)-bTjM-H>alq;oI1!lV2!5>pjKYK!#8PTu=(-;_!j{&1R9p`XeeFDjHBW zZnn(ciDiAz;3!1;B|q^2Sc+*;2gObKiLZ{O{@rPa`m;OsWxug*05vQ&H)?_n$W3Hv z%k*=zJ^>5cKnc!xi4z_BvrqZ9EEoXI&BJniAQah!jeivs&dVOS8{}aDUvL-Lfz&iv zF&UiOc6aQ`e$_Ys;D$HN`UgP>a&-8bU+9Z5B{ozb3&Grt9nb&)tXSd|ps?|L8ykTS zOd0|SypB(k{>t6>$(qx1I-c`wdKR|+IUBy}ASSfiw{3S;8>m8AkZ9Yu+qbbJMRXe> zhb#^z?-z2>pU9fK@x2^hXg{>4j2z#lHvq+!K~o$DV5@+J{A@Y>&KdW8~S^Eo}C0-HbSEjtg&5S{0H5cm+t5VBWhpe!I}L;r_$=ABSMNL?1d058e_ ztU3J@U=YHvREH7agkTuAO>jcA%Oa2klaJtADrUFqY#1#B1tnn)fQ>^y1QbohFo)m> z)0~cJWMO%075K|?APHMRSa;{?GEN7S7qYDW(?Gu^FksD zK+Q}T=4dz^w=3kEC1~8{h@mvyh8;PqV*JlQL1~vW3@?UxW$ClGL1})5jRP`J zum=rAW{aU3>XnZ>JFptP1xc|fEs>tYK^!@7*Vhk9CAW*l+W7jKy5O{5iSF#%cqgof zbAF3~)czB(G;S7Cdvb8FCDPH}S1dv0Y%kUaS#8O<-1>x|AIXKrLc4wIKcE9WM;yYz zI9tf<0=xZX5CduKfzY=x{NTVygvxdb#@E-t=3nZ8feSf=FF^;=(|Y;xvBM#)gg>N= zF2cXr6cv%uc#L6jIEW?BaYxx~*?;SYfPFZwW$*HRdp8_SaF}m=0PF60`w`r&NB|2#wpo-x23H?#id=$xTB{RkKWzyZ++K*0R4q)p5ldI%rMi_C>do%YPw zZT^Q$II5Ze>R~75$N3&KfFXx`HxIT%pCQe-w=Tgy;DM;IipevFLINh#rM}P;wXT9F4nXeT*A7#wh1#8!wL!EGn(KAo*6Dgg(E@)GKkl);9)pJ9&$T)t2uoout3RX!HfQ)xL+#Pnw=`@u<0yRH`tSd zhJk_&#VTxWV|XR%tjf42Jnc$vzZphJ5HI4s{nTf!7lX-6nBLpZKc(b<0B*y`gcI3J zj8a&eHb-D!lN|s*b2DTFf#C2zbHWB?`NgMoO7VP2$U;l0CSb*oO zqcajG#S9f3xf_FVt!Q>)g?(G%V_5aBfq3`>$k>+N1Vw$DMnMMw6+6;V8%>})gjld+ zuV>Ocx?yelniOC2?;%9;BVXl3VCEGICDx+tc?s}R$w~NYKRL_S4=sipR09fq3#$_B1+zKM&ZWCBCnzfz z?1eSkEfIhFI~d!rVBX3x1DTuIyV^hr^?7C|@EdrhS_|!0n}9=NxI+yJpqBX&FqIAm z;fVVwXha-pU`26ROYi|c+RFz!z&PRH{9dqZC# zn|L4H0Y)0fO5g412qqzxEN8BlkmeVrCic zTz82jj$GP{v1+hba-EO#{D2sSY-oBQHm4hs*p`lElvNS(!p;{r3lEFN!xL-R56A@U z2PE--y$vAYybXZi3|pFpv(3UPSV_DMzzD!0qpSTuZZZa|ino2uX;2$*tMCsGuK&V@ zU@mlh9LV5AOm>32ND=H2zJ4zNYezpW+`vy_FHqt*R6d|;PDe+#fACQU?iz6gEf)K~ zhP^UR;=yD9Hf!yLCt;N?m%~Z9J?OlkSLXC3A9i%K6r17<8j6&F)Wo4($Ifd>O?lze zhErzazyxfCMGT1jaL0k{f2@BW4guQ0f$blja3inXR8|x8&{3R8LVaMwNf!9&*`qoa zf`1{ey&dMu&PV2#e}bI~cI={Gb9Cd9o6j5o+rcMR_lqSp9;0jJZI z=q#)r<|8=g6vOm~FnXMV_WBbv5^Pv;UMzt}b|tWUfl;~%JOYF~`Vt{LQy~8ThQzk? 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(A) : (B)) + +PRIVATE paramT p; +PRIVATE int id=-1; + +PUBLIC paramT *scale_parameters(void) +{ + unsigned int i,j,k,l; + double tempf; + /* if ((fabs(p.temperature - temperature)<1e-6)&&(id == p.id)) return &p; */ + + tempf = ((temperature+K0)/Tmeasure); + for (i=0; i<31; i++) + p.hairpin[i] = (int) hairpin37[i]*(tempf); + for (i=0; i<=MIN2(30,MAXLOOP); i++) { + p.bulge[i] = (int) bulge37[i]*tempf; + p.internal_loop[i]= (int) internal_loop37[i]*tempf; + } + p.lxc = lxc37*tempf; + for (; i<=MAXLOOP; i++) { + p.bulge[i] = p.bulge[30]+(int)(p.lxc*log((double)(i)/30.)); + p.internal_loop[i] = p.internal_loop[30]+(int)(p.lxc*log((double)(i)/30.)); + } + for (i=0; i<5; i++) + p.F_ninio[i] = (int) F_ninio37[i]*tempf; + + for (i=0; (i*7)2)?TerminalAU:0; + } + p.MLclosing = ML_closing37*tempf; + + p.TerminalAU = TerminalAU; + + p.DuplexInit = DuplexInit*tempf; + + /* stacks G(T) = H - [H - G(T0)]*T/T0 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + p.stack[i][j] = enthalpies[i][j] - + (enthalpies[i][j] - stack37[i][j])*tempf; + + /* mismatches */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) + for (k=0; k<5; k++) { + p.mismatchI[i][j][k] = mism_H[i][j][k] - + (mism_H[i][j][k] - mismatchI37[i][j][k])*tempf; + p.mismatchH[i][j][k] = mism_H[i][j][k] - + (mism_H[i][j][k] - mismatchH37[i][j][k])*tempf; + p.mismatchM[i][j][k] = mism_H[i][j][k] - + (mism_H[i][j][k] - mismatchM37[i][j][k])*tempf; + } + + /* dangles */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) { + int dd; + dd = dangle5_H[i][j] - (dangle5_H[i][j] - dangle5_37[i][j])*tempf; + p.dangle5[i][j] = (dd>0) ? 0 : dd; /* must be <= 0 */ + dd = dangle3_H[i][j] - (dangle3_H[i][j] - dangle3_37[i][j])*tempf; + p.dangle3[i][j] = (dd>0) ? 0 : dd; /* must be <= 0 */ + } + /* interior 1x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) + p.int11[i][j][k][l] = int11_H[i][j][k][l] - + (int11_H[i][j][k][l] - int11_37[i][j][k][l])*tempf; + + /* interior 2x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m; + for (m=0; m<5; m++) + p.int21[i][j][k][l][m] = int21_H[i][j][k][l][m] - + (int21_H[i][j][k][l][m] - int21_37[i][j][k][l][m])*tempf; + } + /* interior 2x2 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m,n; + for (m=0; m<5; m++) + for (n=0; n<5; n++) + p.int22[i][j][k][l][m][n] = int22_H[i][j][k][l][m][n] - + (int22_H[i][j][k][l][m][n]-int22_37[i][j][k][l][m][n])*tempf; + } + + strncpy(p.Tetraloops, Tetraloops, 1400); + strncpy(p.Triloops, Triloops, 240); + + p.temperature = temperature; + p.id = ++id; + return &p; +} + +PUBLIC paramT *copy_parameters(void) { + paramT *copy; + if (p.id != id) scale_parameters(); + + copy = (paramT *) space(sizeof(paramT)); + memcpy(copy, &p, sizeof(paramT)); + return copy; +} + +PUBLIC paramT *set_parameters(paramT *dest) { + + memcpy(&p, dest, sizeof(paramT)); + return &p; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/params.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/params.o new file mode 100755 index 0000000000000000000000000000000000000000..2c25e0d00180d76b95f9f24d6844b1fc4f21e33b GIT binary patch literal 16848 zcmbuG3v`>sm4N4$WLt?GOMc}25;%~Mhy2Jpq$CbD$RU9|oCLNZLbhdFi!BLBb`l5> zFr?N=OuRs8mJJ1#^fbG0HaTSpc|h}y11XfIWj7q!0$rBPY3MeEbATQw-g{^6mBwQW z+Ou;`{(tT_ckbM|^Z5UNtlVF->;{`<2~L){PGlseLiCK!KzpC%lC+?|^hh?44uO@urzU{;(?&)u( z>K<@(yayJ@UUlksr22hB^%&Nd5bLHmJN;Oy`XBN;dZFzc)ixR~lzH8(>48J@z}fL$ z_4XN98*0?{p21wjAHYh|)WS?JyIs#Nt8&PxZR)zfI=o2-rmtDUEF!0L8o6>5Lqap_GkDtohiHd>H<>ct#& z0OO+deEQjxl)4=iRh?hi!KQo3aj*$OUaI;B`5hmzev0iK%4SVjf{q+hIUL7V^FZ6* zT_U?fj)KLr90?-=FgOl>--)WeH#VOqFFFp&cpSr4{k^g)eid`He`GY^nuh%!KH@;dZpYT8-TBV#CEZvr_0}|p%s|tx!#@au=N*dt1#tKz$`HRUXIgWbs;QLa z5P{-UoP?mPhAdUR(}}~Ds(!@j?>pXiZgWpn-|4E(zc}365`BGr)B*Rl)gVA8WIU92 z`CGRuhbqp4Rfqv98qz|>v)~^R}LJyS2>V60YmtUqv%fRLQTbMe)qoK+U|w6>eSh^N44D!oKExp z8n2!}ufVBaRzWm6|Lo{EpuBsEy?Zb{LM>{9YI~1C;}8`L(X#M`u43t7#k>CS#k*|i zmh=^Tt4*C)2F`+ODtw=Tvk<;5IijhlsmI@NM)%kb(=l&pcZuiQy@pBHLvEk%JJb2K z;+>Bgs@E#_5zpd zI+qZ3$U0TlF#_lU*R`%%7`Ys`aLG(=v1JvbHkJsHH%uwz)E3VhDuff&gc!nAg&0Z- zP#G0m7F0)r`B#YA;xf=3h6Y`^%3J|xJ5`&g?UqUq8jlZ@7Ue5{Cg;}{7g|Nu;#?sL zXQeCHKr8~0d`7Vtnv<$Rl(?YFMev{Z-D$L7q zcCldP=1!AThzoWfJ|l!9-&%*or9z2?)`L=XDzS(}j}nVX9Hqn(61_?sPT~|Ljv%pI zi6cpzr^HbtE>_|g68%aXOX3P8jwA6_B~GyJgl^bM?@*%G!d=2v+M>iOsYfv-UQJ?B ziBqhQ?BFIPPPeWF(O$aMQt}L|R>}{O?6Wq4ZF^}a$(7dkq})aFwN^~(_mEs=VTA3a zyGUL_@-rk?OKX!O1SipaLAX)a z>@+`QYc>a#+DaWt%2@-Fz4RfQ5_6Tf)vm-mC4NPsGbEM2pt?hpxXY!Khbr-4p%PsW zNaYJ7m6)%@FGeYG*bijst}#k1z-=F5zD$Yk4?uL3?m9zmdEBrsfV?-qpmkG&uoXTJ zJ$97t-5lAGJ4n zg_IvUO!AmJq`c<{$zzp&yI#!~E({@>m*beHuEK?}O4A8K1}iNqEr--~2p5LREE6t_ zm_dzt7{qVVVEY){Z`WgO3~gE)yu(nXtJ7(d#g3x!u(*VFf6PIOQ@vq?{(o$U1-&WB2>2~;wWJ%&Ktyb zVPm7P)}o^_6;B;Zr%hPlv`Pu<^1Tp>6I@&v(F9!2*l*9H=^j3qwTH^v&U64gz3EEZ zvsN08PFUO1l}4a!e*`xk%TmHlO~}o|U{Fc!P~0O}aOpw;PG>H0>w-rYigA9kT8SJt1uw1-F1bP%NQs&n^2=hybTo%8KOook%a zLCrTTw!=OIh0D(Wu+7Nd0iw&p6Q{8m-{$qiM9Bv-{I%C1-z;M(a8IVH&OA>?<@)pheDpmPRW% zt6mFX^@{bJEucVJVg+Z5X%he~&W=f=6`Vaz6A-k>o%D^HJDFCwJzYkbwbblS(<-Y? 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(x) : (y)) +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define PUBLIC +#define PRIVATE static + +PUBLIC float pf_fold(char *sequence, char *structure); +PUBLIC void init_pf_fold(int length); +PUBLIC void free_pf_arrays(void); +PUBLIC void update_pf_params(int length); +PUBLIC char bppm_symbol(float *x); +PUBLIC int st_back=0; +PRIVATE void sprintf_bppm(int length, char *structure); +PRIVATE void scale_pf_params(unsigned int length); +PRIVATE void get_arrays(unsigned int length); +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1); +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string); +PRIVATE void make_ptypes(const short *S, const char *structure); + +PRIVATE FLT_OR_DBL expMLclosing, expMLintern[NBPAIRS+1], *expMLbase; +PRIVATE FLT_OR_DBL expTermAU; +PRIVATE FLT_OR_DBL expdangle5[NBPAIRS+1][5], expdangle3[NBPAIRS+1][5]; +PRIVATE FLT_OR_DBL lxc, exptetra[40], expTriloop[40]; +PRIVATE FLT_OR_DBL expstack[NBPAIRS+1][NBPAIRS+1]; +PRIVATE FLT_OR_DBL expmismatchI[NBPAIRS+1][5][5], + expmismatchH[NBPAIRS+1][5][5], expmismatchM[NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint11[NBPAIRS+1][NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint21[NBPAIRS+1][NBPAIRS+1][5][5][5]; +PRIVATE FLT_OR_DBL expint22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; +PRIVATE FLT_OR_DBL *exphairpin; +PRIVATE FLT_OR_DBL expbulge[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expinternal[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expninio[5][MAXLOOP+1]; +PRIVATE FLT_OR_DBL *q, *qb, *qm, *qm1, *qqm, *qqm1, *qq, *qq1; +PRIVATE FLT_OR_DBL *prml, *prm_l, *prm_l1, *q1k, *qln; +PRIVATE FLT_OR_DBL *scale; +PRIVATE char *ptype; /* precomputed array of pair types */ +PRIVATE int *jindx; +PRIVATE int init_length; /* length in last call to init_pf_fold() */ +PRIVATE double init_temp; /* temperature in last call to scale_pf_params */ +#define ISOLATED 256.0 + +/*-----------------------------------------------------------------*/ +static short *S, *S1; +PUBLIC float pf_fold(char *sequence, char *structure) +{ + + int n, i,j,k,l, ij, kl, u,u1,d,ii,ll, type, type_2, tt, ov=0; + FLT_OR_DBL temp, Q, Qmax=0, prm_MLb; + FLT_OR_DBL prmt,prmt1; + FLT_OR_DBL qbt1, *tmp; + + double free_energy; + double max_real; + + max_real = (sizeof(FLT_OR_DBL) == sizeof(float)) ? FLT_MAX : DBL_MAX; + + n = (int) strlen(sequence); + if (n>init_length) init_pf_fold(n); /* (re)allocate space */ + if ((init_temp - temperature)>1e-6) update_pf_params(n); + + S = (short *) xrealloc(S, sizeof(short)*(n+1)); + S1= (short *) xrealloc(S1, sizeof(short)*(n+1)); + S[0] = n; + for (l=1; l<=n; l++) { + S[l] = (short) encode_char(toupper(sequence[l-1])); + S1[l] = alias[S[l]]; + } + make_ptypes(S, structure); + + /*array initialization ; qb,qm,q + qb,qm,q (i,j) are stored as ((n+1-i)*(n-i) div 2 + n+1-j */ + + for (d=0; d<=TURN; d++) + for (i=1; i<=n-d; i++) { + j=i+d; + ij = iindx[i]-j; + q[ij]=1.0*scale[d+1]; + qb[ij]=qm[ij]=0.0; + } + + for (i=1; i<=n; i++) + qq[i]=qq1[i]=qqm[i]=qqm1[i]=prm_l[i]=prm_l1[i]=prml[i]=0; + + for (j=TURN+2;j<=n; j++) { + for (i=j-TURN-1; i>=1; i--) { + /* construction of partition function of segment i,j*/ + /*firstly that given i bound to j : qb(i,j) */ + u = j-i-1; ij = iindx[i]-j; + type = ptype[ij]; + if (type!=0) { + /*hairpin contribution*/ + if (((type==3)||(type==4))&&no_closingGU) qbt1 = 0; + else + qbt1 = expHairpinEnergy(u, type, S1[i+1], S1[j-1], sequence+i-1); + + /* interior loops with interior pair k,l */ + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); l1) qbt1 *= expdangle5[type][S1[i-1]]; + if (j2) qbt1 *= expTermAU; + qqm[i] += qbt1; + } + if (qm1) qm1[jindx[j]+i] = qqm[i]; /* for stochastic backtracking */ + + /*construction of qm matrix containing multiple loop + partition function contributions from segment i,j */ + temp = 0.0; + ii = iindx[i]; /* ii-k=[i,k-1] */ + for (k=i+1; k<=j; k++) temp += (qm[ii-(k-1)]+expMLbase[k-i])*qqm[k]; + qm[ij] = (temp + qqm[i]); + + /*auxiliary matrix qq for cubic order q calculation below */ + qbt1 = qb[ij]; + if (type) { + if (i>1) qbt1 *= expdangle5[type][S1[i-1]]; + if (j2) qbt1 *= expTermAU; + } + qq[i] = qq1[i]*scale[1] + qbt1; + + /*construction of partition function for segment i,j */ + temp = 1.0*scale[1+j-i] + qq[i]; + for (k=i; k<=j-1; k++) temp += q[ii-k]*qq[k+1]; + q[ij] = temp; + + if (temp>Qmax) { + Qmax = temp; + if (Qmax>max_real/10.) + fprintf(stderr, "Q close to overflow: %d %d %g\n", i,j,temp); + } + if (temp>=max_real) { + PRIVATE char msg[128]; + sprintf(msg, "overflow in pf_fold while calculating q[%d,%d]\n" + "use larger pf_scale", i,j); + nrerror(msg); + } + } + tmp = qq1; qq1 =qq; qq =tmp; + tmp = qqm1; qqm1=qqm; qqm=tmp; + } + if (backtrack_type=='C') Q = qb[iindx[1]-n]; + else if (backtrack_type=='M') Q = qm[iindx[1]-n]; + else Q = q[iindx[1]-n]; + + /* ensemble free energy in Kcal/mol */ + if (Q<=FLT_MIN) fprintf(stderr, "pf_scale too large\n"); + free_energy = (-log(Q)-n*log(pf_scale))*(temperature+K0)*GASCONST/1000.0; + /* in case we abort because of floating point errors */ + if (n>1600) fprintf(stderr, "free energy = %8.2f\n", free_energy); + + /* backtracking to construct binding probabilities of pairs*/ + + if (do_backtrack) { + Qmax=0; + + for (k=1; k<=n; k++) { + q1k[k] = q[iindx[1] - k]; + qln[k] = q[iindx[k] -n]; + } + q1k[0] = 1.0; + qln[n+1] = 1.0; + + pr = q; /* recycling */ + + /* 1. exterior pair i,j and initialization of pr array */ + for (i=1; i<=n; i++) { + for (j=i; j<=MIN(i+TURN,n); j++) pr[iindx[i]-j] = 0; + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + type = ptype[ij]; + if (type&&(qb[ij]>0.)) { + pr[ij] = q1k[i-1]*qln[j+1]/q1k[n]; + if (i>1) pr[ij] *= expdangle5[type][S1[i-1]]; + if (j2) pr[ij] *= expTermAU; + } else + pr[ij] = 0; + } + } + + for (l=n; l>TURN+1; l--) { + + /* 2. bonding k,l as substem of 2:loop enclosed by i,j */ + for (k=1; k0)) { + pr[kl] += pr[ij]*expLoopEnergy(k-i-1, j-l-1, type, type_2, + S1[i+1], S1[j-1], S1[k-1], S1[l+1]); + } + } + } + /* 3. bonding k,l as substem of multi-loop enclosed by i,j */ + prm_MLb = 0.; + if (l1) temp *= expdangle5[tt][S1[k-1]]; + if (lQmax) { + Qmax = pr[kl]; + if (Qmax>max_real/10.) + fprintf(stderr, "P close to overflow: %d %d %g %g\n", + i, j, pr[kl], qb[kl]); + } + if (pr[kl]>=max_real) { + ov++; + pr[kl]=FLT_MAX; + } + + } /* end for (k=..) */ + tmp = prm_l1; prm_l1=prm_l; prm_l=tmp; + + } /* end for (l=..) */ + + for (i=1; i<=n; i++) + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + pr[ij] *= qb[ij]; + } + + if (structure!=NULL) + sprintf_bppm(n, structure); + } /* end if (do_backtrack)*/ + + if (ov>0) fprintf(stderr, "%d overflows occurred while backtracking;\n" + "you might try a smaller pf_scale than %g\n", + ov, pf_scale); + + return free_energy; +} + +/*------------------------------------------------------------------------*/ +/* dangling ends should never be destabilizing, i.e. expdangle>=1 */ +/* specific heat needs smooth function (2nd derivative) */ +/* we use a*(sin(x+b)+1)^2, with a=2/(3*sqrt(3)), b=Pi/6-sqrt(3)/2, */ +/* in the interval b0.8660254)?(X):\ + SCALE*0.38490018*(sin((X)/SCALE-0.34242663)+1)*(sin((X)/SCALE-0.34242663)+1)) +/* #define SMOOTH(X) ((X)<0 ? 0 : (X)) */ + +PRIVATE void scale_pf_params(unsigned int length) +{ + /* scale energy parameters and pre-calculate Boltzmann weights */ + unsigned int i, j, k, l; + double kT, TT; + double GT; + + + init_temp = temperature; + kT = (temperature+K0)*GASCONST; /* kT in cal/mol */ + TT = (temperature+K0)/(Tmeasure); + + /* scaling factors (to avoid overflows) */ + if (pf_scale==-1) { /* mean energy for random sequences: 184.3*length cal */ + pf_scale = exp(-(-185+(temperature-37.)*7.27)/kT); + if (pf_scale<1) pf_scale=1; + } + scale[0] = 1.; + for (i=1; i<=length; i++) { + scale[i] = scale[i-1]/pf_scale; + } + + /* loop energies: hairpins, bulges, interior, mulit-loops */ + for (i=0; i<=MIN(30,length); i++) { + GT = hairpin37[i]*TT; + exphairpin[i] = exp( -GT*10./kT); + } + for (i=0; i<=MIN(30, MAXLOOP); i++) { + GT = bulge37[i]*TT; + expbulge[i] = exp( -GT*10./kT); + GT = internal_loop37[i]*TT; + expinternal[i] = exp( -GT*10./kT); + } + /* special case of size 2 interior loops (single mismatch) */ + if (james_rule) expinternal[2] = exp ( -80*10/kT); + + lxc = lxc37*TT; + for (i=31; i2) GT += TerminalAU; */ + expMLintern[i] = exp( -GT*10./kT); + } + expTermAU = exp(-TerminalAU*10/kT); + + GT = ML_BASE37*TT; + for (i=0; i 0 (at large temps), + but make sure go smoothly to 0 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=4; j++) { + if (dangles) { + GT = dangle5_H[i][j] - (dangle5_H[i][j] - dangle5_37[i][j])*TT; + expdangle5[i][j] = exp(SMOOTH(-GT)*10./kT); + GT = dangle3_H[i][j] - (dangle3_H[i][j] - dangle3_37[i][j])*TT; + expdangle3[i][j] = exp(SMOOTH(-GT)*10./kT); + } else + expdangle3[i][j] = expdangle5[i][j] = 1; + if (i>2) /* add TermAU penalty into dangle3 */ + expdangle3[i][j] *= expTermAU; + } + + /* stacking energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) { + GT = enthalpies[i][j] - (enthalpies[i][j] - stack37[i][j])*TT; + expstack[i][j] = exp( -GT*10/kT); + } + + /* mismatch energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) + for (k=0; k<5; k++) { + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchI37[i][j][k])*TT; + expmismatchI[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchH37[i][j][k])*TT; + expmismatchH[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchM37[i][j][k])*TT; + expmismatchM[i][j][k] = exp(-GT*10.0/kT); + } + + /* interior lops of length 2 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + GT = int11_H[i][j][k][l] - + (int11_H[i][j][k][l] - int11_37[i][j][k][l])*TT; + expint11[i][j][k][l] = exp(-GT*10./kT); + } + /* interior 2x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m; + for (m=0; m<5; m++) { + GT = int21_H[i][j][k][l][m] - + (int21_H[i][j][k][l][m] - int21_37[i][j][k][l][m])*TT; + expint21[i][j][k][l][m] = exp(-GT*10./kT); + } + } + /* interior 2x2 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m,n; + for (m=0; m<5; m++) + for (n=0; n<5; n++) { + GT = int22_H[i][j][k][l][m][n] - + (int22_H[i][j][k][l][m][n]-int22_37[i][j][k][l][m][n])*TT; + expint22[i][j][k][l][m][n] = exp(-GT*10./kT); + } + } +} + +/*----------------------------------------------------------------------*/ +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string) { + double q; + q = exphairpin[u]; + if ((tetra_loop)&&(u==4)) { + char tl[7]={0}, *ts; + strncpy(tl, string, 6); + if ((ts=strstr(Tetraloops, tl))) + q *= exptetra[(ts-Tetraloops)/7]; + } + if (u==3) { + char tl[6]={0}, *ts; + strncpy(tl, string, 5); + if ((ts=strstr(Triloops, tl))) + q *= expTriloop[(ts-Triloops)/6]; + if (type>2) + q *= expTermAU; + } + else /* no mismatches for tri-loops */ + q *= expmismatchH[type][si1][sj1]; + + q *= scale[u+2]; + return q; +} + +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1) { + double z=0; + int no_close = 0; + + if ((no_closingGU) && ((type2==3)||(type2==4)||(type==2)||(type==4))) + no_close = 1; + + if ((u1==0) && (u2==0)) /* stack */ + z = expstack[type][type2]; + else if (no_close==0) { + if ((u1==0)||(u2==0)) { /* bulge */ + int u; + u = (u1==0)?u2:u1; + z = expbulge[u]; + if (u2+u1==1) z *= expstack[type][type2]; + else { + if (type>2) z *= expTermAU; + if (type2>2) z *= expTermAU; + } + } + else { /* interior loop */ + if (u1+u2==2) /* size 2 is special */ + z = expint11[type][type2][si1][sj1]; + else if ((u1==1) && (u2==2)) + z = expint21[type][type2][si1][sq1][sj1]; + else if ((u1==2) && (u2==1)) + z = expint21[type2][type][sq1][si1][sp1]; + else if ((u1==2) && (u2==2)) + z = expint22[type][type2][si1][sp1][sq1][sj1]; + else { + z = expinternal[u1+u2]* + expmismatchI[type][si1][sj1]* + expmismatchI[type2][sq1][sp1]; + z *= expninio[2][abs(u1-u2)]; + } + } + } + return z*scale[u1+u2+2]; +} + +/*----------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int length) +{ + unsigned int size,i; + + size = sizeof(FLT_OR_DBL) * ((length+1)*(length+2)/2); + q = (FLT_OR_DBL *) space(size); + qb = (FLT_OR_DBL *) space(size); + qm = (FLT_OR_DBL *) space(size); + + if (st_back) { + qm1 = (FLT_OR_DBL *) space(size); + } + ptype = (char *) space(sizeof(char)*((length+1)*(length+2)/2)); + q1k = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + qln = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l1 =(FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prml = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + exphairpin = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + expMLbase = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + scale = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + iindx = (int *) space(sizeof(int)*(length+1)); + jindx = (int *) space(sizeof(int)*(length+1)); + for (i=1; i<=length; i++) { + iindx[i] = ((length+1-i)*(length-i))/2 +length+1; + jindx[i] = (i*(i-1))/2; + } +} + +/*----------------------------------------------------------------------*/ + +PUBLIC void init_pf_fold(int length) +{ + if (length<1) nrerror("init_pf_fold: length must be greater 0"); + if (init_length>0) free_pf_arrays(); /* free previous allocation */ +#ifdef SUN4 + nonstandard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(1); +#endif +#endif + make_pair_matrix(); + get_arrays((unsigned) length); + scale_pf_params((unsigned) length); + init_length=length; +} + +PUBLIC void free_pf_arrays(void) +{ + free(q); q=pr=NULL; + free(qb); + free(qm); + if (qm1 != NULL) {free(qm1); qm1 = NULL;} + free(ptype); + free(qq); free(qq1); + free(qqm); free(qqm1); + free(q1k); free(qln); + free(prm_l); free(prm_l1); free(prml); + free(exphairpin); + free(expMLbase); + free(scale); + free(iindx); free(jindx); +#ifdef SUN4 + standard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(0); +#endif +#endif + init_length=0; + free(S); S=NULL; + free(S1); S1=NULL; +} +/*---------------------------------------------------------------------------*/ + +PUBLIC void update_pf_params(int length) +{ + if (length>init_length) init_pf_fold(length); /* init not update */ + else { + make_pair_matrix(); + scale_pf_params((unsigned) length); + } +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char bppm_symbol(float *x) +{ + if( x[0] > 0.667 ) return '.'; + if( x[1] > 0.667 ) return '('; + if( x[2] > 0.667 ) return ')'; + if( (x[1]+x[2]) > x[0] ) { + if( (x[1]/(x[1]+x[2])) > 0.667) return '{'; + if( (x[2]/(x[1]+x[2])) > 0.667) return '}'; + else return '|'; + } + if( x[0] > (x[1]+x[2]) ) return ','; + return ':'; +} + +/*---------------------------------------------------------------------------*/ +#define L 3 +PRIVATE void sprintf_bppm(int length, char *structure) +{ + int i,j; + float P[L]; /* P[][0] unpaired, P[][1] upstream p, P[][2] downstream p */ + + for( j=1; j<=length; j++ ) { + P[0] = 1.0; + P[1] = P[2] = 0.0; + for( i=1; in) continue; + type = pair[S[i]][S[j]]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j': /* pairs downstream */ + for (l=j+TURN+1; l<=n; l++) ptype[iindx[j]-l] = 0; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in constraint string"); + } + free(stack); + } +} + +/* + stochastic backtracking in pf_fold arrays + returns random structure S with Boltzman probabilty + p(S) = exp(-E(S)/kT)/Z +*/ +static void backtrack(int i, int j); + +static char *pstruc; +static char *sequence; +char *pbacktrack(char *seq) { + double r, qt; + int i,j,n, start; + + sequence = seq; + n = strlen(sequence); + + if (init_length<1) + nrerror("can't backtrack without pf arrays.\n" + "Call pf_fold() before pbacktrack()"); + pstruc = space((n+1)*sizeof(char)); + + for (i=0; i qln[i+1]*scale[1]) break; /* i is paired */ + } + if (i>=n) break; /* no more pairs */ + /* now find the pairing partner j */ + r = urn() * (qln[i] - qln[i+1]*scale[1]); + for (qt=0, j=i+1; j<=n; j++) { + int type; + type = ptype[iindx[i]-j]; + if (type) { + double qkl; + qkl = qb[iindx[i]-j]; + if (j1) qkl *= expdangle5[type][S1[i-1]]; + if (j2) qkl *= expTermAU; + qt += qkl; + if (qt > r) break; /* j is paired */ + } + } + if (j==n+1) nrerror("backtracking failed in ext loop"); + start = j+1; + backtrack(i,j); + } + + return pstruc; +} + +static void backtrack_qm1(int i,int j) { + /* i is paired to l, i=r) break; + } + if (l>j) nrerror("backtrack failed in qm1"); + backtrack(i,l); +} + +static void backtrack(int i, int j) { + do { + double r, qbt1; + int k, l, type, u, u1; + + pstruc[i-1] = '('; pstruc[j-1] = ')'; + + r = urn() * qb[iindx[i]-j]; + type = ptype[iindx[i]-j]; + u = j-i-1; + /*hairpin contribution*/ + if (((type==3)||(type==4))&&no_closingGU) qbt1 = 0; + else + qbt1 = expHairpinEnergy(u, type, S1[i+1], S1[j-1], sequence+i-1); + + if (qbt1>r) return; /* found the hairpin we're done */ + + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); l r) break; + } + if (qbt1 > r) break; + } + if (l=r) break; + } + if (k>=j) nrerror("backtrack failed, can't find split index "); + + backtrack_qm1(k, j); + + j = k-1; + while (j>i) { + /* now backtrack [i ... j] in qm[] */ + jj = jindx[j]; + ii = iindx[i]; + r = urn() * qm[ii - j]; + qt = qm1[jj+i]; k=i; + if (qt= r) break; + } + if (k>j) nrerror("backtrack failed in qm"); + + backtrack_qm1(k,j); + + if (k= r) break; /* no more pairs */ + j = k-1; + } + } +} + +PUBLIC double mean_bp_dist(int length) { + /* compute the mean base pair distance in the thermodynamic ensemble */ + /* = \sum_{a,b} p_a p_b d(S_a,S_b) + this can be computed from the pair probs p_ij as + = \sum_{ij} p_{ij}(1-p_{ij}) */ + int i,j; + double d=0; + + if (pr==NULL) + nrerror("pr==NULL. You need to call pf_fold() before mean_bp_dist()"); + + for (i=1; i<=length; i++) + for (j=i+TURN+1; j<=length; j++) + d += pr[iindx[i]-j] * (1-pr[iindx[i]-j]); + return d; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/part_func.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/part_func.o new file mode 100755 index 0000000000000000000000000000000000000000..3ba5b8c28e957404d3ac7ba3d3f21794515b2b17 GIT binary patch literal 77168 zcmd443w%`7wLgC5feaFu08vm7Mj4dw2!w|cKw)446AT(42|(EA)q1Z zm<$iA7AsoX+KQ<4QLEUh1dxYX74U_%Dxz&k5ka-z}C=wpQHKl3!6LqNm9 zy6zLbFYb+IHAnV`>R%Z&Z zy}y~VB=3yu7uk?g{vXH*Wap$FpC!uaLU|fq_BNcxJrv$u5_yymqjh)vX?NY{C3}TX zm!Sx!k$PN_#Qt{R&!lK-Ybf$gD4Os#<;?It{#7Wvw{>qQnsinu>UPw(c5HMv(4&a^ zZo1VSCg~mPwg+W3(;E)fB*}v4u|;Jz4kaM<`1FS3-i955q(ZlGq5DJ8Q9>jNZH5A( zlu)=^<5?)aeuq0$zb6~TbGd()UTRQd0!kq_~_MVT3bP_80^RlA3hpDDl>8<@Ej=^ z+6b)*RNyJiyHrT$x&w_y;7 z7sz+eGOfEy_O7A4hO2GT**58r$@MKa&Eao`ft?u>I;;xf03PLQK<`g}^lSLdXPWA(j=Wkbk3jOV)=XbNxpnUp0;f 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file mode 100755 index 00000000..9f2c3e59 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/part_func_co.c @@ -0,0 +1,1372 @@ +/* Last changed Time-stamp: <2006-01-19 12:16:02 ivo> */ +/* + partiton function for RNA secondary structures + + Ivo L Hofacker + Stephan Bernhart + Vienna RNA package +*/ +/* + $Log: part_func_co.c,v $ + Revision 1.7 2006/01/19 11:30:04 ivo + compute_probabilities should only look at one dimer at a time + + Revision 1.6 2006/01/18 12:55:40 ivo + major cleanup of berni code + fix bugs related to confusing which free energy is returned by co_pf_fold() + + Revision 1.5 2006/01/16 11:32:25 ivo + small bug in multiloop pair probs + + Revision 1.4 2006/01/05 18:13:40 ivo + update + + Revision 1.3 2006/01/04 15:14:29 ivo + fix bug in concentration calculations + + Revision 1.2 2004/12/23 12:14:41 berni + *** empty log message *** + + Revision 1.1 2004/12/22 10:46:17 berni + + Partition function Cofolding 0.9, Computation of concentrations. + + Revision 1.16 2003/08/04 09:14:09 ivo + finish up stochastic backtracking + + Revision 1.15 2002/03/19 16:51:12 ivo + more on stochastic backtracking (still incomplete) + + Revision 1.13 2001/11/16 17:30:04 ivo + add stochastic backtracking (still incomplete) +*/ + +#include +#include +#include +#include +#include +#include /* #defines FLT_MAX ... */ +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "PS_dot.h" +#include "part_func_co.h" +/*@unused@*/ +static char rcsid[] UNUSED = "$Id: part_func_co.c,v 1.7 2006/01/19 11:30:04 ivo Exp $"; + +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define PUBLIC +#define PRIVATE static + +PUBLIC cofoldF co_pf_fold(char *sequence, char *structure); +PUBLIC void init_co_pf_fold(int length); +PUBLIC void free_co_pf_arrays(void); +PUBLIC void update_co_pf_params(int length); +PUBLIC char co_bppm_symbol(float *x); + +PUBLIC struct ConcEnt *get_concentrations(double FEAB, double FEAA, double FEBB, double FEA, double FEB, double *startconc); +PUBLIC struct plist *get_plist(struct plist *pl, int length, double cut_off); +PUBLIC struct plist *get_mfe_plist(struct plist *pl); +PUBLIC double F_monomer[2]; /* free energies of the two monomers */ +/* PUBLIC int make_probsum(int length, char *name); */ +PRIVATE double *Newton_Conc(double ZAB, double ZAA, double ZBB, double concA, double concB,double* ConcVec); +PRIVATE void sprintf_bppm(int length, char *structure); +PRIVATE void scale_pf_params(unsigned int length); +PRIVATE void get_arrays(unsigned int length); +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1); +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string); +PRIVATE void make_ptypes(const short *S, const char *structure); + +PRIVATE FLT_OR_DBL expMLclosing, expMLintern[NBPAIRS+1], *expMLbase; +PRIVATE FLT_OR_DBL expTermAU; +PRIVATE FLT_OR_DBL expdangle5[NBPAIRS+1][5], expdangle3[NBPAIRS+1][5]; +PRIVATE FLT_OR_DBL lxc, exptetra[40], expTriloop[40]; +PRIVATE FLT_OR_DBL expstack[NBPAIRS+1][NBPAIRS+1]; +PRIVATE FLT_OR_DBL expmismatchI[NBPAIRS+1][5][5], + expmismatchH[NBPAIRS+1][5][5], expmismatchM[NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint11[NBPAIRS+1][NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint21[NBPAIRS+1][NBPAIRS+1][5][5][5]; +PRIVATE FLT_OR_DBL expint22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; +PRIVATE FLT_OR_DBL *exphairpin; +PRIVATE FLT_OR_DBL expbulge[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expInit; +PRIVATE FLT_OR_DBL expinternal[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expninio[5][MAXLOOP+1]; +PRIVATE FLT_OR_DBL *q, *qb, *qm, *qm1, *qqm, *qqm1, *qq, *qq1; +PRIVATE FLT_OR_DBL *prml, *prm_l, *prm_l1, *q1k, *qln; +PRIVATE FLT_OR_DBL *scale; +PRIVATE char *ptype; /* precomputed array of pair types */ +PRIVATE int *jindx; +PRIVATE int init_length; /* length in last call to init_pf_fold() */ +#define ISOLATED 256.0 +#undef TURN +#define TURN 0 +#define SAME_STRAND(I,J) (((I)>=cut_point)||((J)init_length) init_co_pf_fold(n); /* (re)allocate space */ + /* printf("mirnatog=%d\n",mirnatog); */ + S = (short *) xrealloc(S, sizeof(short)*(n+1)); + S1= (short *) xrealloc(S1, sizeof(short)*(n+1)); + S[0] = n; + for (l=1; l<=n; l++) { + S[l] = (short) encode_char(toupper(sequence[l-1])); + S1[l] = alias[S[l]]; + } + make_ptypes(S, structure); + + /*array initialization ; qb,qm,q + qb,qm,q (i,j) are stored as ((n+1-i)*(n-i) div 2 + n+1-j */ + + /* for (d=0; d<=TURN; d++) */ + for (i=1; i<=n/*-d*/; i++) { + ij = iindx[i]-i; + q[ij]=scale[1]; + qb[ij]=qm[ij]=0.0; + } + + for (i=1; i<=n; i++) + qq[i]=qq1[i]=qqm[i]=qqm1[i]=prm_l[i]=prm_l1[i]=prml[i]=0; + + for (j=TURN+2;j<=n; j++) { + for (i=j-TURN-1; i>=1; i--) { + /* construction of partition function of segment i,j*/ + /*firstly that given i bound to j : qb(i,j) */ + u = j-i-1; ij = iindx[i]-j; + type = ptype[ij]; + qbt1=0; + if (type!=0) { + /*hairpin contribution*/ + if SAME_STRAND(i,j){ + if (((type==3)||(type==4))&&no_closingGU) qbt1 = 0; + else + qbt1 = expHairpinEnergy(u, type, S1[i+1], S1[j-1], sequence+i-1); + + } + + /* interior loops with interior pair k,l */ + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); lcut_point) temp*=scale[1]; + if (i2) temp*= expTermAU; + if (SAME_STRAND(j-1,j)) temp*=expdangle5[tt][S1[j-1]]; + + qbt1+=temp; + } + qb[ij] = qbt1; + } /* end if (type!=0) */ + else qb[ij] = 0.0; + + /* construction of qqm matrix containing final stem + contributions to multiple loop partition function + from segment i,j */ + if (SAME_STRAND(j-1,j)) { + qqm[i] = qqm1[i]*expMLbase[1]; + } + else qqm[i]=0; + if (type&&SAME_STRAND(i-1,i)&&SAME_STRAND(j,j+1)) { + qbt1 = qb[ij]*expMLintern[type]; + if (i>1) qbt1 *= expdangle5[type][S1[i-1]]; + if (j2) qbt1 *= expTermAU; + qqm[i] += qbt1; + } + + if (qm1) qm1[jindx[j]+i] = qqm[i]; /* for stochastic backtracking */ + + + /*construction of qm matrix containing multiple loop + partition function contributions from segment i,j */ + temp = 0.0; + ii = iindx[i]; /* ii-k=[i,k] */ + + for (k=i+1; k<=j; k++) { + if (SAME_STRAND(k-1,k)) temp += (qm[ii-(k-1)])*qqm[k]; + if (SAME_STRAND(i,k)) temp +=expMLbase[k-i]*qqm[k]; + + } + + qm[ij] = (temp + qqm[i]); + + /*auxiliary matrix qq for cubic order q calculation below */ + qbt1 = qb[ij]; + if (type) { + if ((i>1)&&(SAME_STRAND(i-1,i))) qbt1 *= expdangle5[type][S1[i-1]]; + if ((j2) qbt1 *= expTermAU; + } + qq[i] = qq1[i]*scale[1] + qbt1; + /*construction of partition function for segment i,j */ + temp = 1.0*scale[1+j-i] + qq[i]; + for (k=i; k<=j-1; k++) { + temp += q[ii-k]*qq[k+1]; + } + q[ij] = temp; + + if (temp>Qmax) { + Qmax = temp; + if (Qmax>max_real/10.) + fprintf(stderr, "Q close to overflow: %d %d %g\n", i,j,temp); + } + if (temp>=max_real) { + PRIVATE char msg[128]; + sprintf(msg, "overflow in pf_fold while calculating q[%d,%d]\n" + "use larger pf_scale", i,j); + nrerror(msg); + } + } + tmp = qq1; qq1 =qq; qq =tmp; + tmp = qqm1; qqm1=qqm; qqm=tmp; + } + if (backtrack_type=='C') Q = qb[iindx[1]-n]; + else if (backtrack_type=='M') Q = qm[iindx[1]-n]; + else Q = q[iindx[1]-n]; + /* ensemble free energy in Kcal/mol */ + if (Q<=FLT_MIN) fprintf(stderr, "pf_scale too large\n"); + free_energy = (-log(Q)-n*log(pf_scale))*(temperature+K0)*GASCONST/1000.0; + /* in case we abort because of floating point errors */ + if (n>1600) fprintf(stderr, "free energy = %8.2f\n", free_energy); + /*probability of molecules being bound together*/ + + + /*Computation of "real" Partition function*/ + /*Need that for concentrations*/ + if (cut_point>0){ + double kT, pbound, QAB, QToT, Qzero; + kT = (temperature+K0)*GASCONST/1000.0; + Qzero=q[iindx[1]-n]; + QAB=(q[iindx[1]-n]-q[iindx[1]-(cut_point-1)]*q[iindx[cut_point]-n])*expInit; + QToT=q[iindx[1]-(cut_point-1)]*q[iindx[cut_point]-n]+QAB; + pbound=1-(q[iindx[1]-(cut_point-1)]*q[iindx[cut_point]-n]/QToT); + + X.FAB = -kT*(log(QToT)+n*log(pf_scale)); + X.F0AB = -kT*(log(Qzero)+n*log(pf_scale)); + X.FcAB = (QAB>1e-17) ? -kT*(log(QAB)+n*log(pf_scale)) : 999; + X.FA = -kT*(log(q[iindx[1]-(cut_point-1)]) + (cut_point-1)*log(pf_scale)); + X.FB = -kT*(log(q[iindx[cut_point]-n]) + (n-cut_point+1)*log(pf_scale)); + + /* printf("QAB=%.9f\tQtot=%.9f\n",QAB/scale[n],QToT/scale[n]);*/ + } + else { + X.FA = X.FB = X.FAB = X.F0AB = free_energy; + X.FcAB = 0; + } + /* printf("freen=%.6f\n",free_energy); whereto?*/ + /* backtracking to construct binding probabilities of pairs*/ + /* printf("qis %f\n",q[iindx[1]-(cut_point-1)]);*/ + /*new: expInit added*/ /*new*/ + if (do_backtrack) { + Qmax=0; + + for (k=1; k<=n; k++) { + q1k[k] = q[iindx[1] - k]; + qln[k] = q[iindx[k] -n]; + } + q1k[0] = 1.0; + qln[n+1] = 1.0; + + /* pr = q; / * recycling */ + + /* 1. exterior pair i,j and initialization of pr array */ + for (i=1; i<=n; i++) { + for (j=i; j<=MIN(i+TURN,n); j++) pr[iindx[i]-j] = 0; + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + type = ptype[ij]; + if (type&&(qb[ij]>0.)) { + pr[ij] = q1k[i-1]*qln[j+1]/q1k[n]; + if ((i>1)&&(SAME_STRAND(i-1,i))) pr[ij] *= expdangle5[type][S1[i-1]]; + if ((j2) pr[ij] *= expTermAU; + } else + pr[ij] = 0; + } + } + + for (l=n; l>TURN+1; l--) { + + /* 2. bonding k,l as substem of 2:loop enclosed by i,j */ + for (k=1; k0)) { + pr[kl] += pr[ij]*expLoopEnergy(k-i-1, j-l-1, type, type_2, + S1[i+1], S1[j-1], S1[k-1], S1[l+1]); + } + } + } + } + /* 3. bonding k,l as substem of multi-loop enclosed by i,j */ + prm_MLb = 0.; + if ((l1)&&SAME_STRAND(k-1,k)) temp *= expdangle5[tt][S1[k-1]]; + if ((lQmax) { + Qmax = pr[kl]; + if (Qmax>max_real/10.) + fprintf(stderr, "P close to overflow: %d %d %g %g\n", + i, j, pr[kl], qb[kl]); + } + if (pr[kl]>=max_real) { + ov++; + pr[kl]=FLT_MAX; + } + + } /* end for (k=..) multloop*/ + else /* set prm_l to 0 to get prm_l1 to be 0 */ + for (i=0; i<=n; i++) prm_l[i]=0; + + tmp = prm_l1; prm_l1=prm_l; prm_l=tmp; + /*computation of .(..(...)..&..). type features?*/ + + if (cut_point<=0) continue; /* no .(..(...)..&..). type features*/ + if ((l==n)||(l<=2)) continue; /* no .(..(...)..&..). type features*/ + if (l>cut_point) { /*right of cut*/ + /*k=cut_point*/ + kl=iindx[cut_point]-l; + if (qb[kl]>0.) { + tt=ptype[kl]; + /*i0.) { + type=ptype[iindx[i]-(l+1)]; type=rtype[type]; + pr[kl]+=q[iindx[i+1]-(cut_point-1)]*pr[iindx[i]-(l+1)]* + expdangle5[type][S1[l]]*expdangle3[type][S1[i+1]]* + expdangle3[tt][S1[l+1]]*scale[2]; + + } + /*j>l+1*/ + for (j=l+2; j<=n; j++) { + if (qb[iindx[i]-(j)]>0.) { + type=ptype[iindx[i]-(j)]; type=rtype[type]; + pr[kl]+=q[iindx[i+1]-(cut_point-1)]*pr[iindx[i]-(j)]* + expdangle5[type][S1[j-1]]*expdangle3[type][S1[i+1]]* + expdangle3[tt][S1[l+1]]*q[iindx[l+1]-(j-1)]*scale[2]; + + } + } + } + i=cut_point-1; /*i=cut_point-1; */ + /*j==l+1*/ + if (qb[iindx[i]-(l+1)]>0.) { + type=ptype[iindx[i]-(l+1)]; type=rtype[type]; + temp=pr[iindx[i]-(l+1)]*expdangle5[type][S1[l]]* + expdangle3[tt][S1[l+1]]*scale[2]; + if (type>2) temp*=expTermAU; + pr[kl]+=temp; + + } + /*j>l+1*/ + for (j=l+2; j<=n; j++) { + if (qb[iindx[i]-(j)]>0.) { + type=ptype[iindx[i]-(j)]; type=rtype[type]; + temp=pr[iindx[i]-(j)]*expdangle5[type][S1[j-1]]* + expdangle3[tt][S1[l+1]]*q[iindx[l+1]-(j-1)]*scale[2]; + if (type>2) temp*=expTermAU; + pr[kl]+=temp; + + } + } + } + + for (k=cut_point+1; kcut_point*/ + kl=iindx[k]-l; + if (qb[kl]>0.) { + tt=ptype[kl]; + /*i0.) { + type=ptype[iindx[i]-(l+1)]; type=rtype[type]; + pr[kl]+=q[iindx[cut_point]-(k-1)]*q[iindx[i+1]-(cut_point-1)]* + pr[iindx[i]-(l+1)]*expdangle5[type][S1[l]]* + expdangle3[type][S1[i+1]]*expdangle3[tt][S1[l+1]]* + expdangle5[tt][S1[k-1]]*scale[2]; + } + /*j>l+1*/ + for (j=l+2; j<=n; j++) { + if (qb[iindx[i]-(j)]>0.) { + type=ptype[iindx[i]-(j)]; type=rtype[type]; + pr[kl]+=q[iindx[cut_point]-(k-1)]*q[iindx[i+1]-(cut_point-1)]* + pr[iindx[i]-(j)]*expdangle5[type][S1[j-1]]* + expdangle3[type][S1[i+1]]*expdangle3[tt][S1[l+1]]* + q[iindx[l+1]-(j-1)]*expdangle5[tt][S1[k-1]]*scale[2]; + } + } + } + i=cut_point-1; /*i=cut_point-1; */ + /*j==l+1*/ + if (qb[iindx[i]-(l+1)]>0.) { + type=ptype[iindx[i]-(l+1)]; type=rtype[type]; + temp=q[iindx[cut_point]-(k-1)]*pr[iindx[i]-(l+1)]* + expdangle5[type][S1[l]]*expdangle3[tt][S1[l+1]]* + expdangle5[tt][S1[k-1]]*scale[2]; + if (type>2) temp*=expTermAU; + pr[kl]+=temp; + } + /*j>l+1*/ + for (j=l+2; j<=n; j++) { + if (qb[iindx[i]-(j)]>0.) { + type=ptype[iindx[i]-(j)]; type=rtype[type]; + temp=q[iindx[cut_point]-(k-1)]*pr[iindx[i]-(j)]* + expdangle5[type][S1[j-1]]*expdangle3[tt][S1[l+1]]* + q[iindx[l+1]-(j-1)]*expdangle5[tt][S1[k-1]]*scale[2]; + if (type>2) temp*=expTermAU; + pr[kl]+=temp; + } + } + } + } + } + if (l0.) { + tt=ptype[kl]; /*i=k-1*/ + if (qb[iindx[k-1]-cut_point]>0.) { /*j=cut_point*/ + type=ptype[iindx[k-1]-cut_point];type=rtype[type]; + pr[kl]+=pr[iindx[k-1]-cut_point]*q[iindx[l+1]-(cut_point-1)]* + expdangle3[tt][S1[l+1]]*expdangle5[tt][S1[k-1]]* + expdangle3[type][S1[k]]*scale[2]; + + } + + for (j=cut_point+1; j<=n;j++) { /*j ab cut_point+1*/ + if (qb[iindx[k-1]-j]>0.) { + type=ptype[iindx[k-1]-j];type=rtype[type]; + pr[kl]+=pr[iindx[k-1]-j]*q[iindx[l+1]-(cut_point-1)]* + q[iindx[cut_point]-(j-1)]*expdangle3[tt][S1[l+1]]* + expdangle5[tt][S1[k-1]]*expdangle5[type][S1[j-1]]* + expdangle3[type][S1[k]]*scale[2]; + } + } + /*i0.) { /*j=cut_point*/ + type=ptype[iindx[i]-cut_point];type=rtype[type]; + pr[kl]+=pr[iindx[i]-cut_point]*q[iindx[l+1]-(cut_point-1)]* + expdangle3[tt][S1[l+1]]*expdangle5[tt][S1[k-1]]* + expdangle3[type][S1[i+1]]*q[iindx[i+1]-(k-1)]*scale[2]; + } + + for (j=cut_point+1; j<=n;j++) { /*j ab cut_point+1*/ + if (qb[iindx[i]-j]>0.) { + type=ptype[iindx[i]-j];type=rtype[type]; + pr[kl]+=pr[iindx[i]-j]*q[iindx[l+1]-(cut_point-1)]* + q[iindx[cut_point]-(j-1)]*expdangle3[tt][S1[l+1]]* + expdangle5[tt][S1[k-1]]*expdangle5[type][S1[j-1]]* + expdangle3[type][S1[i+1]]*q[iindx[i+1]-(k-1)]*scale[2]; + } + } + } + } + } + } + /*l=cut_point-1*/ + if (l==cut_point-1) { + for(k=2; k0.) { + tt=ptype[kl]; /*i=k-1*/ + if (qb[iindx[k-1]-cut_point]>0.) { /*j=cut_point*/ + type=ptype[iindx[k-1]-cut_point];type=rtype[type]; + temp=pr[iindx[k-1]-cut_point]*expdangle5[tt][S1[k-1]]* + expdangle3[type][S1[k]]*scale[2]; + if (tt>2) temp*=expTermAU; + pr[kl]+=temp; + } + + for (j=cut_point+1; j<=n;j++) { /*j ab cut_point+1*/ + if (qb[iindx[k-1]-j]>0.) { + type=ptype[iindx[k-1]-j];type=rtype[type]; + temp=pr[iindx[k-1]-j]*q[iindx[cut_point]-(j-1)]* + expdangle5[tt][S1[k-1]]*expdangle5[type][S1[j-1]]* + expdangle3[type][S1[k]]*scale[2]; + if (tt>2) temp*=expTermAU; + pr[kl]+=temp; + } + } + /*i0.) { /*j=cut_point*/ + type=ptype[iindx[i]-cut_point];type=rtype[type]; + temp=pr[iindx[i]-cut_point]*expdangle5[tt][S1[k-1]]* + expdangle3[type][S1[i+1]]*q[iindx[i+1]-(k-1)]*scale[2]; + if (tt>2) temp*=expTermAU; + pr[kl]+=temp; + } + + for (j=cut_point+1; j<=n;j++) { /*j ab cut_point+1*/ + if (qb[iindx[i]-j]>0.) { + type=ptype[iindx[i]-j];type=rtype[type]; + temp=pr[iindx[i]-j]*q[iindx[cut_point]-(j-1)]* + expdangle5[tt][S1[k-1]]*expdangle5[type][S1[j-1]]* + expdangle3[type][S1[i+1]]*q[iindx[i+1]-(k-1)]*scale[2]; + if (tt>2) temp*=expTermAU; + pr[kl]+=temp; + } + } + + } + } + } + } + + } /* end for (l=..) */ + + for (i=1; i<=n; i++) + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + pr[ij] *= qb[ij]; + } + + if (structure!=NULL) + sprintf_bppm(n, structure); + } /* end if (do_backtrack)*/ + + if (ov>0) fprintf(stderr, "%d overflows occurred while backtracking;\n" + "you might try a smaller pf_scale than %g\n", + ov, pf_scale); + return X; +} + +/*------------------------------------------------------------------------*/ +/* dangling ends should never be destabilizing, i.e. expdangle>=1 */ +/* specific heat needs smooth function (2nd derivative) */ +/* we use a*(sin(x+b)+1)^2, with a=2/(3*sqrt(3)), b=Pi/6-sqrt(3)/2, */ +/* in the interval b0.8660254)?(X):\ + SCALE*0.38490018*(sin((X)/SCALE-0.34242663)+1)*(sin((X)/SCALE-0.34242663)+1))*/ +#define SMOOTH(X) ((X)<0 ? 0 : (X)) + +PRIVATE void scale_pf_params(unsigned int length) +{ + /* scale energy parameters and pre-calculate Boltzmann weights */ + unsigned int i, j, k, l; + double kT, TT; + double GT; + + + + kT = (temperature+K0)*GASCONST; /* kT in cal/mol */ + TT = (temperature+K0)/(Tmeasure); + + /* scaling factors (to avoid overflows) */ + if (pf_scale==-1) { /* mean energy for random sequences: 184.3*length cal */ + pf_scale = exp(-(-185+(temperature-37.)*7.27)/kT); + if (pf_scale<1) pf_scale=1; + } + scale[0] = 1.; + for (i=1; i<=length; i++) { + scale[i] = scale[i-1]/pf_scale; + } + + /* loop energies: hairpins, bulges, interior, mulit-loops */ + for (i=0; i<=MIN(30,length); i++) { + GT = hairpin37[i]*TT; + exphairpin[i] = exp( -GT*10./kT); + } + for (i=0; i<=MIN(30, MAXLOOP); i++) { + GT = bulge37[i]*TT; + expbulge[i] = exp( -GT*10./kT); + GT = internal_loop37[i]*TT; + expinternal[i] = exp( -GT*10./kT); + } + /* special case of size 2 interior loops (single mismatch) */ + if (james_rule) expinternal[2] = exp ( -80*10/kT); + + lxc = lxc37*TT; + for (i=31; i2) GT += TerminalAU; */ + expMLintern[i] = exp( -GT*10./kT); + } + expTermAU = exp(-TerminalAU*10/kT); + + GT = ML_BASE37*TT; + for (i=0; i 0 (at large temps), + but make sure go smoothly to 0 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=4; j++) { + if (dangles) { + GT = dangle5_H[i][j] - (dangle5_H[i][j] - dangle5_37[i][j])*TT; + expdangle5[i][j] = exp(SMOOTH(-GT)*10./kT); + GT = dangle3_H[i][j] - (dangle3_H[i][j] - dangle3_37[i][j])*TT; + expdangle3[i][j] = exp(SMOOTH(-GT)*10./kT); + } else + expdangle3[i][j] = expdangle5[i][j] = 1; + if (i>2) /* add TermAU penalty into dangle3 */ + expdangle3[i][j] *= expTermAU; + } + + /* stacking energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) { + GT = enthalpies[i][j] - (enthalpies[i][j] - stack37[i][j])*TT; + expstack[i][j] = exp( -GT*10/kT); + } + + /* mismatch energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) + for (k=0; k<5; k++) { + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchI37[i][j][k])*TT; + expmismatchI[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchH37[i][j][k])*TT; + expmismatchH[i][j][k] = exp(-GT*10.0/kT); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchM37[i][j][k])*TT; + expmismatchM[i][j][k] = exp(-GT*10.0/kT); + } + + /* interior lops of length 2 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + GT = int11_H[i][j][k][l] - + (int11_H[i][j][k][l] - int11_37[i][j][k][l])*TT; + expint11[i][j][k][l] = exp(-GT*10./kT); + } + /* interior 2x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m; + for (m=0; m<5; m++) { + GT = int21_H[i][j][k][l][m] - + (int21_H[i][j][k][l][m] - int21_37[i][j][k][l][m])*TT; + expint21[i][j][k][l][m] = exp(-GT*10./kT); + } + } + /* interior 2x2 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m,n; + for (m=0; m<5; m++) + for (n=0; n<5; n++) { + GT = int22_H[i][j][k][l][m][n] - + (int22_H[i][j][k][l][m][n]-int22_37[i][j][k][l][m][n])*TT; + expint22[i][j][k][l][m][n] = exp(-GT*10./kT); + } + } + /*initialization of duplex energy*/ + expInit=exp(-DuplexInit*TT*10./kT); +} + +/*----------------------------------------------------------------------*/ +PRIVATE double expHairpinEnergy(int u, int type, short si1, short sj1, + const char *string) { + double q; + q = exphairpin[u]; + if ((tetra_loop)&&(u==4)) { + char tl[7]={0}, *ts; + strncpy(tl, string, 6); + if ((ts=strstr(Tetraloops, tl))) + q *= exptetra[(ts-Tetraloops)/7]; + } + if (u==3) { + char tl[6]="", *ts; + strncpy(tl, string, 5); + if ((ts=strstr(Triloops, tl))) + q *= expTriloop[(ts-Triloops)/6]; + if (type>2) + q *= expTermAU; + } + else /* no mismatches for tri-loops */ + q *= expmismatchH[type][si1][sj1]; + + q *= scale[u+2]; + return q; +} + +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1) { + double z=0; + int no_close = 0; + + if ((no_closingGU) && ((type2==3)||(type2==4)||(type==2)||(type==4))) + no_close = 1; + + if ((u1==0) && (u2==0)) /* stack */ + z = expstack[type][type2]; + else if (no_close==0) { + if ((u1==0)||(u2==0)) { /* bulge */ + int u; + u = (u1==0)?u2:u1; + z = expbulge[u]; + if (u2+u1==1) z *= expstack[type][type2]; + else { + if (type>2) z *= expTermAU; + if (type2>2) z *= expTermAU; + } + } + else { /* interior loop */ + if (u1+u2==2) /* size 2 is special */ + z = expint11[type][type2][si1][sj1]; + else if ((u1==1) && (u2==2)) + z = expint21[type][type2][si1][sq1][sj1]; + else if ((u1==2) && (u2==1)) + z = expint21[type2][type][sq1][si1][sp1]; + else if ((u1==2) && (u2==2)) + z = expint22[type][type2][si1][sp1][sq1][sj1]; + else { + z = expinternal[u1+u2]* + expmismatchI[type][si1][sj1]* + expmismatchI[type2][sq1][sp1]; + z *= expninio[2][abs(u1-u2)]; + } + } + } + return z*scale[u1+u2+2]; +} + +/*----------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int length) +{ + unsigned int size,i; + + size = sizeof(FLT_OR_DBL) * ((length+1)*(length+2)/2); + q = (FLT_OR_DBL *) space(size); + qb = (FLT_OR_DBL *) space(size); + qm = (FLT_OR_DBL *) space(size); + pr = (FLT_OR_DBL *) space(size); /*q is needed later*/ + + qm1 = (FLT_OR_DBL *) space(size); + + ptype = (char *) space(sizeof(char)*((length+1)*(length+2)/2)); + q1k = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + + qln = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l1 =(FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prml = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + exphairpin = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + expMLbase = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + scale = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + iindx = (int *) space(sizeof(int)*(length+1)); + jindx = (int *) space(sizeof(int)*(length+1)); + for (i=1; i<=length; i++) { + iindx[i] = ((length+1-i)*(length-i))/2 +length+1; + jindx[i] = (i*(i-1))/2; + } +} + +/*----------------------------------------------------------------------*/ + +PUBLIC void init_co_pf_fold(int length) +{ + if (length<1) nrerror("init_pf_fold: length must be greater 0"); + if (init_length>0) free_co_pf_arrays(); /* free previous allocation */ +#ifdef SUN4 + nonstandard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(1); +#endif +#endif + make_pair_matrix(); + get_arrays((unsigned) length); + scale_pf_params((unsigned) length); + init_length=length; +} + +PUBLIC void free_co_pf_arrays(void) +{ + free(q); + free(qb); + free(qm); + free(pr); + if (qm1 != NULL) {free(qm1); qm1 = NULL;} + free(ptype); + free(qq); free(qq1); + free(qqm); free(qqm1); + free(q1k); free(qln); + free(prm_l); free(prm_l1); free(prml); + free(exphairpin); + free(expMLbase); + free(scale); + free(iindx); + free(jindx); +#ifdef SUN4 + standard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(0); +#endif +#endif + init_length=0; + free(S); S=NULL; + free(S1); S1=NULL; +} +/*---------------------------------------------------------------------------*/ + +PUBLIC void update_co_pf_params(int length) +{ + make_pair_matrix(); + scale_pf_params((unsigned) length); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC char co_bppm_symbol(float *x) +{ + if( x[0] > 0.667 ) return '.'; + if( x[1] > 0.667 ) return '('; + if( x[2] > 0.667 ) return ')'; + if( (x[1]+x[2]) > x[0] ) { + if( (x[1]/(x[1]+x[2])) > 0.667) return '{'; + if( (x[2]/(x[1]+x[2])) > 0.667) return '}'; + else return '|'; + } + if( x[0] > (x[1]+x[2]) ) return ','; + return ':'; +} + +/*---------------------------------------------------------------------------*/ +#define L 3 +PRIVATE void sprintf_bppm(int length, char *structure) +{ + int i,j; + float P[L]; /* P[][0] unpaired, P[][1] upstream p, P[][2] downstream p */ + + for( j=1; j<=length; j++ ) { + P[0] = 1.0; + P[1] = P[2] = 0.0; + for( i=1; in) continue; + type = pair[S[i]][S[j]]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j': /* pairs downstream */ + for (l=j+TURN+1; l<=n; l++) ptype[iindx[j]-l] = 0; + break; + case 'l': /*only intramolecular basepairing*/ + if (j=r) break; + } + if (l>j) nrerror("backtrack failed in qm1"); + backtrack(i,l); +} + +static void backtrack(int i, int j) { + do { + double r, qbt1; + int k, l, type, u, u1; + + pstruc[i-1] = '('; pstruc[j-1] = ')'; + + r = urn() * qb[iindx[i]-j]; + type = ptype[iindx[i]-j]; + u = j-i-1; + /*hairpin contribution*/ + if (((type==3)||(type==4))&&no_closingGU) qbt1 = 0; + else + qbt1 = expHairpinEnergy(u, type, S1[i+1], S1[j-1], sequence+i-1); + + if (qbt1>r) return; /* found the hairpin we're done */ + + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); l r) break; + } + if (qbt1 > r) break; + } + if (l=r) break; + } + if (k>=j) nrerror("backtrack failed, can't find split index "); + + backtrack_qm1(k, j); + + j = k-1; + while (j>i) { + /* now backtrack [i ... j] in qm[] */ + jj = jindx[j]; + ii = iindx[i]; + r = urn() * qm[ii - j]; + qt = qm1[jj+i]; k=i; + if (qt= r) break; + } + if (k>j) nrerror("backtrack failed in qm"); + + backtrack_qm1(k,j); + + if (k= r) break; /* no more pairs */ + j = k-1; + } + } +} + +PUBLIC void compute_probabilities(double FAB, double FA,double FB, + struct plist *prAB, + struct plist *prA, struct plist *prB, + int Alength) { + /*computes binding probabilities and dimer free energies*/ + int i, j; + double pAB; + double mykT;; + struct plist *lp1, *lp2; + int offset; + + mykT=(temperature+K0)*GASCONST/1000.; + + /* pair probabilities in pr are relative to the null model (without DuplexInit) */ + + /*Compute probabilities pAB, pAA, pBB*/ + + pAB=1.-exp((1/mykT)*(FAB-FA-FB)); + + /* compute pair probabilities given that it is a dimer */ + /* AB dimer */ + offset=0; + lp2=prA; + if (pAB>0) + for (lp1=prAB; lp1->j>0; lp1++) { + float pp=0; + i=lp1->i; j=lp1->j; + while (offset+lp2->i < i && lp2->i>0) lp2++; + if (offset+lp2->i == i) + while ((offset+lp2->j) < j && (lp2->j>0)) lp2++; + if (lp2->j == 0) {lp2=prB; offset=Alength;}/* jump to next list */ + if ((offset+lp2->i==i) && (offset+lp2->j ==j)) { + pp = lp2->p; + lp2++; + } + lp1->p=(lp1->p-(1-pAB)*pp)/pAB; + } + return; +} + +PRIVATE double *Newton_Conc(double KAB, double KAA, double KBB, double concA, double concB,double* ConcVec) { + double TOL, EPS, xn, yn, det, cA, cB; + int i=0; + /*Newton iteration for computing concentrations*/ + cA=concA; + cB=concB; + TOL=0.000000000000001; /*Tolerance for convergence*/ + ConcVec=(double*)space(5*sizeof(double)); /* holds concentrations */ + do { + det = (4.0 * KAA * cA + KAB *cB + 1.0) * (4.0 * KBB * cB + KAB *cA + 1.0) - (KAB *cB) * (KAB *cA); + xn = ( (2.0 * KBB * cB*cB + KAB *cA *cB + cB - concB) * (KAB *cA) - + (2.0 * KAA * cA*cA + KAB *cA *cB + cA - concA) * (4.0 * KBB * cB + KAB *cA + 1.0) ) /det; + yn = ( (2.0 * KAA * cA*cA + KAB *cA *cB + cA - concA) * (KAB *cB) - + (2.0 * KBB * cB*cB + KAB *cA *cB + cB - concB) * (4.0 * KAA * cA + KAB *cB + 1.0) ) /det; + EPS = fabs(xn) + fabs(yn); + cA += xn; + cB += yn; + i++; + if (i>10000) { + fprintf(stderr, "Newton did not converge after %d steps!!\n",i); + break; + } + } while(EPS>TOL); + + ConcVec[0]= cA*cB*KAB ;/*AB concentration*/ + ConcVec[1]= cA*cA*KAA ;/*AA concentration*/ + ConcVec[2]= cB*cB*KBB ;/*BB concentration*/ + ConcVec[3]= cA; /* A concentration*/ + ConcVec[4]= cB; /* B concentration*/ + + return ConcVec; +} + +PUBLIC struct ConcEnt *get_concentrations(double FcAB, double FcAA, double FcBB, double FEA, double FEB, double *startconc) +{ + /*takes an array of start concentrations, computes equilibrium concentrations of dimers, monomers, returns array of concentrations in strucutre ConcEnt*/ + double *ConcVec; + int i; + struct ConcEnt *Concentration; + double KAA, KAB, KBB, kT; + + kT=(temperature+K0)*GASCONST/1000.; + Concentration=(struct ConcEnt *)space(20*sizeof(struct ConcEnt)); + /* Compute equilibrium constants */ + /* again note the input free energies are not from the null model (without DuplexInit) */ + + KAA = exp(( 2.0 * FEA - FcAA)/kT); + KBB = exp(( 2.0 * FEB - FcBB)/kT); + KAB = exp(( FEA + FEB - FcAB)/kT); + printf("Kaa..%g %g %g\n", KAA, KBB, KAB); + for (i=0; ((startconc[i]!=0)||(startconc[i+1]!=0));i+=2) { + ConcVec=Newton_Conc(KAB, KAA, KBB, startconc[i], startconc[i+1], ConcVec); + Concentration[i/2].A0=startconc[i]; + Concentration[i/2].B0=startconc[i+1]; + Concentration[i/2].ABc=ConcVec[0]; + Concentration[i/2].AAc=ConcVec[1]; + Concentration[i/2].BBc=ConcVec[2]; + Concentration[i/2].Ac=ConcVec[3]; + Concentration[i/2].Bc=ConcVec[4]; + + if (!(((i+2)/2)%20)) { + Concentration=(struct ConcEnt *)xrealloc(Concentration,((i+2)/2+20)*sizeof(struct ConcEnt)); + } + free(ConcVec); + } + + return Concentration; +} + +PUBLIC struct plist *get_plist(struct plist *pl, int length, double cut_off) { + int i, j,n, count; + /*get pair probibilities out of pr array*/ + count=0; + n=2; + for (i=1; i??*/ + pl[count++].p=0.; + pl=(struct plist *)xrealloc(pl,(count)*sizeof(struct plist)); + return pl; +} + + +#if 0 +PUBLIC int make_probsum(int length, char *name) { + /*compute probability of any base to be paired (preliminary)*/ + double *Spprob; + double *Pprob; + int i,j; + FILE *fp; + char *filename; + filename=(char *)space((strlen(name)+10)*sizeof(char)); + sprintf(filename,"%s_pp.dat",name); + fp=fopen(filename,"w"); + Spprob=(double *)space((length+1)*sizeof(double)); + if (cut_point>0) Pprob=(double *)space((length+1)*sizeof(double)); + for (i=1; i0) for (i=1;i<=length; i++) { + fprintf(fp,"%4d %.8f\n",i,Pprob[i]); + } + fclose(fp); + free(Spprob); + free(filename); + if (cut_point>0) free(Pprob); + return 1; +} +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/part_func_co.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/part_func_co.o new file mode 100755 index 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parameters from a file + + Stephan Kopp, Ivo Hofacker + Vienna RNA Package +*/ + + +#include +#include +#include +#include +#include + +#include "utils.h" +#include "energy_const.h" +#include "energy_par.h" + +static char rcsid[] = "$Id: read_epars.c,v 1.10 2004/12/10 16:32:35 ivo Exp $"; + +#define PUBLIC +#define PRIVATE static +#define PARSET 20 +enum parset {UNKNOWN= -1, QUIT, S, SH, HP, B, IL, MMI, MMH, MMM, MM_H, + DE5, DE3, DE5_H, DE3_H, ML, TL, TRI, TE, NIN, MISC, + INT11, INT11_H, INT21, INT21_H, INT22, INT22_H, DUMP, HELP}; + + +/*------------------ identifiers ----------------------------*/ +#define DEF -50 +#define NST 0 + +#define DEF_TEMP 37.0 /* default temperature */ + +/*----------------------- prototypes -------------------------*/ +PUBLIC void read_parameter_file(const char fname[]); +PUBLIC void write_parameter_file(const char fname[]); + +PRIVATE void rd_stacks(int stack[NBPAIRS+1][NBPAIRS+1]); +PRIVATE void rd_loop(int looparray[31]); +PRIVATE void rd_mismatch(int mismatch[NBPAIRS+1][5][5]); +PRIVATE void rd_int11(int int11[NBPAIRS+1][NBPAIRS+1][5][5]); +PRIVATE void rd_int21(int int21[NBPAIRS+1][NBPAIRS+1][5][5][5]); +PRIVATE void rd_int22(int int22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]); +PRIVATE void rd_dangle(int dangles[NBPAIRS+1][5]); +PRIVATE void rd_MLparams(void); +PRIVATE void rd_misc(void); +PRIVATE void rd_ninio(void); +PRIVATE void rd_Tetra_loop(void); +PRIVATE void rd_Tri_loop(void); +PRIVATE void check_symmetry(void); + +PRIVATE enum parset gettype(char ident[]); +PRIVATE char *get_array1(int *arr, int size); + +PRIVATE void ignore_comment(char *line); + +PRIVATE void display_array(int *p, int size, int line, FILE *fp); + +/*------------------------------------------------------------*/ +PRIVATE FILE *fp; +PRIVATE float rtemp=DEF_TEMP; + +/*------------------------------------------------------------*/ +PUBLIC void read_parameter_file(const char fname[]) +{ + char *line, ident[32]; + enum parset type; + int r, changed=0; + + if (!(fp=fopen(fname,"r"))) { + fprintf(stderr, + "\nread_parameter_file:\n" + "\t\tcan't open file %s\n" + "\t\tusing default parameters instead.\n", fname); + return; + } + + if (!(line = get_line(fp))) { + fprintf(stderr," File %s is inproper.\n", fname); + fclose(fp); + return; + } + + if (strncmp(line,"## RNAfold parameter file",25)!=0) { + fprintf(stderr, + "Missing header line in file.\n" + "May be this file has incorrect format.\n" + "Use INTERRUPT-key to stop.\n"); + } + free(line); + + while((line=get_line(fp))) { + + r = sscanf(line, "# %31s", ident); + if (r==1) { + type = gettype(ident); + switch (type) + { + case QUIT: break; + case SH: rd_stacks(enthalpies); changed |= SH; break; + case S: rd_stacks(stack37); changed |= S; break; + case HP: rd_loop(hairpin37); changed |= HP; break; + case B: rd_loop(bulge37); changed |= B; break; + case IL: rd_loop(internal_loop37); changed |= IL; break; + case MMH: rd_mismatch(mismatchH37); changed |= MMH; break; + case MMI: rd_mismatch(mismatchI37); changed |= MMI; break; + case MMM: rd_mismatch(mismatchM37); changed |= MMM; break; + case MM_H: rd_mismatch(mism_H); changed |= MM_H; break; + case INT11: rd_int11(int11_37); changed |= INT11; break; + case INT11_H:rd_int11(int11_H); changed |= INT11_H; break; + case INT21: rd_int21(int21_37); changed |= INT21; break; + case INT21_H:rd_int21(int21_H); changed |= INT21_H; break; + case INT22: rd_int22(int22_37); changed |= INT22; break; + case INT22_H:rd_int22(int22_H); changed |= INT22_H; break; + case DE5: rd_dangle(dangle5_37); changed |= DE5; break; + case DE5_H: rd_dangle(dangle5_H); changed |= DE5_H; break; + case DE3: rd_dangle(dangle3_37); changed |= DE3; break; + case DE3_H: rd_dangle(dangle3_H); changed |= DE3_H; break; + case ML: rd_MLparams(); changed |= ML; break; + case NIN: rd_ninio(); changed |= NIN; break; + case TL: rd_Tetra_loop(); changed |= TL; break; + case TRI: rd_Tri_loop(); changed |= TRI; break; + case MISC: rd_misc(); changed |= MISC; break; + + default: /* maybe it's a temperature */ + r=sscanf(ident, "%f", &rtemp); + if (r!=1) fprintf(stderr," Unknown field identifier in `%s'\n", line); + } + } /* else ignore line */ + free(line); + } + + fclose(fp); + + check_symmetry(); + return; +} + +/*------------------------------------------------------------*/ + +PRIVATE void display_array(int *p, int size, int nl, FILE *fp) +{ + int i; + + for (i=1; i<=size; i++, p++) { + switch(*p) + { + case INF: fprintf(fp," INF"); break; + case -INF: fprintf(fp," -INf"); break; + case DEF: fprintf(fp," DEF"); break; + default: fprintf(fp,"%6d", *p); break; + } + if ((i%nl)==0) fprintf(fp,"\n"); + } + if (size%nl) fprintf(fp,"\n"); + return; +} + +/*------------------------------------------------------------*/ + +PRIVATE char *get_array1(int *arr, int size) +{ + int i, p, pos, pp, r, last; + char *line, buf[16]; + + + i = last = 0; + while( i}sqdUR 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(x) : (y)) +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MIN3(x,y,z) (MIN( (MIN((x),(y))) ,(z))) +#define INFINITY 10000 + +PUBLIC float string_edit_distance(swString *T1, swString *T2); +PUBLIC swString *Make_swString(char *string); +PUBLIC void print_swString(swString *x); +PUBLIC void print_alignment_list(void); + +PRIVATE void sprint_aligned_swStrings(swString *T1, swString *T2); +PRIVATE float StrEditCost(int i, int j, swString *T1, swString *T2); +PRIVATE void DeCode(char *string, int k, int *tp, float *w); +PRIVATE int decode(char *id); +PRIVATE void encode(int type, char label[]); +PRIVATE int *alignment[2]; /* contains information from backtracking + alignment[0][n] is the node in tree2 + matching node n in tree1 */ + + +/*---------------------------------------------------------------------------*/ + +PUBLIC float string_edit_distance(swString *T1, swString *T2) + +{ + float **distance; + short **i_point, **j_point; + + int i, j, i1, j1, pos, length1,length2; + float minus, plus, change, temp; + + if (cost_matrix==0) EditCost = &UsualCost; + else EditCost = &ShapiroCost; + + length1 = T1[0].sign; + length2 = T2[0].sign; + + distance = (float **) space((length1 +1)*sizeof(float *)); + if(edit_backtrack){ + i_point = (short **) space((length1 +1)*sizeof(short *)); + j_point = (short **) space((length1 +1)*sizeof(short *)); + } + for(i=0; i<= length1; i++){ + distance[i] = (float *) space( (length2+1)*sizeof(float)); + if(edit_backtrack){ + i_point[i] = (short *) space( (length2+1)*sizeof(short)); + j_point[i] = (short *) space( (length2+1)*sizeof(short)); + } + } + + for(i = 1; i <= length1; i++) { + if (edit_backtrack){ + i_point[i][0] = i-1; + j_point[i][0] = 0; + } + distance[i][0] = distance[i-1][0]+StrEditCost(i,0,T1,T2); + } + for(j = 1; j <= length2; j++) { + if (edit_backtrack){ + j_point[0][j] = j-1; + i_point[0][j] = 0; + } + distance[0][j] = distance[0][j-1]+StrEditCost(0,j,T1,T2); + } + + for (i = 1; i <= length1; i++) { + for (j = 1; j <= length2 ; j++) { + minus = distance[i-1][j] + StrEditCost(i,0,T1,T2); + plus = distance[i][j-1] + StrEditCost(0,j,T1,T2); + change = distance[i-1][j-1]+ StrEditCost(i,j,T1,T2); + + distance[i][j] = MIN3(minus, plus, change); + /* printf("%g ", distance[i][j]); */ + + if(edit_backtrack){ + if(distance[i][j] == change) { + i_point[i][j]=i-1; j_point[i][j]=j-1; } + else if(distance[i][j] == plus) { + i_point[i][j]=i ; j_point[i][j]=j-1; } + else { + i_point[i][j]=i-1; j_point[i][j]=j ; } + } + } + /* printf("\n"); */ + } + /* printf("\n"); */ + temp = distance[length1][length2]; + for(i=0;i<=length1;i++) + free(distance[i]); + free(distance); + + if(edit_backtrack){ + if(alignment[0]!= NULL) free(alignment[0]); + if(alignment[1]!= NULL) free(alignment[1]); + alignment[0] = (int *) space((length1+length2+1)*sizeof(int)); + alignment[1] = (int *) space((length1+length2+1)*sizeof(int)); + + pos = length1+length2; + i = length1; + j = length2; + while( (i>0)||(j>0) ) { + i1 = i_point[i][j]; + j1 = j_point[i][j]; + if( ((i-i1)==1)&&((j-j1)==1) ) { /* substitution */ + alignment[0][pos] = i; + alignment[1][pos] = j; + } + if( ((i-i1)==1)&&(j==j1) ) { /* Deletion in [1] */ + alignment[0][pos] = i; + alignment[1][pos] = 0; + } + if( (i==i1)&&((j-j1)==1) ) { /* Deletion in [0] */ + alignment[0][pos] = 0; + alignment[1][pos] = j; + } + pos--; + i = i1; + j = j1; + } + for(i=pos+1; i<=length1+length2; i++){ + alignment[0][i-pos] = alignment[0][i]; + alignment[1][i-pos] = alignment[1][i]; + } + alignment[0][0] = length1+length2-pos; /* length of alignment */ + + for(i=0; i<=length1; i++){ + free(i_point[i]); free(j_point[i]); + } + free(i_point); free(j_point); + sprint_aligned_swStrings(T1,T2); + + } + + return temp; +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE float StrEditCost(int i, int j, swString *T1, swString *T2) +{ + float c, diff, cd, min, a, b, dist; + + if(i==0) { + cd = (float) (*EditCost)[0][T2[j].type]; + diff = T2[j].weight; + dist = cd*diff; + } + else + if(j==0) { + cd = (float) (*EditCost)[T1[i].type][0]; + diff = T1[i].weight; + dist = cd*diff; + } + else + if( ((T1[i].sign)*(T2[j].sign)) > 0) { + c = (float) (*EditCost)[T1[i].type][T2[j].type]; + diff = (float) fabs((a=T1[i].weight) - (b=T2[j].weight)); + min = MIN(a,b); + if (min == a) cd = (float) (*EditCost)[0][T2[j].type]; + else cd = (float) (*EditCost)[T1[i].type][0]; + dist = c * min + cd * diff; + } + else dist = (float) INFINITY; + return dist; +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC swString *Make_swString(char *string) +{ + int i=0, j=0, k=0; + int tp, len, l, length; + float w; + swString *S; + + length = strlen(string); + + for(i=0; i0) { + k++; + if(string[k] == '(' ) l++; + if(string[k] == ')' ) l--; + } + DeCode(string,k,&tp,&w); + S[j].type = tp; + S[j].weight = w/2.0; + j++; + break; + case ')' : + k=i; + S[j].sign = -1; + DeCode(string,k,&tp,&w); + S[j].type = tp; + S[j].weight = w/2.0; + j++; + break; + case '.' : + S[j].sign = 1; + S[j].type = 1; + S[j].weight = 0.5; + j++; + S[j].sign = -1; + S[j].type = 1; + S[j].weight = 0.5; + j++; + break; + } + i++; + } + return S; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void DeCode(char *string, int k, int *tp, float *w) + /* retrieves type and weigth for a node closed by a bracket at position k */ +{ + int i,j,l,m; + char label[20], id[20] ; + i=k; + label[0] = '\0'; + while(i>=0){ + i--; + if( (string[i]=='(')||(string[i]==')')||(string[i]=='.') ) break; + else { + label[k-i-1] = string[i]; label[k-i] = '\0'; + } + } + l=strlen(label); + if (l==0) { /* Dot-Bracket notation */ + *w = 1.0; + *tp = 2; + } + else{ + for (i=0; i=0){ + for(j=0; j<=l; j++) + id[j] = label[l-j]; + label[l+1] ='\0'; + m=-1; + sscanf(label,"%d",&m); + *w= (float) m; + if(m==-1) { + fprintf(stderr, "Warning: Non-integer weight in DeCode ignored\n"); + *w=1.0; + } + } + else + *w=1.0; + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int decode(char *id) +{ + int n, quit, i; + char label[100], *code; + + n = 0; + + quit = 0; + code = coding; + + while (!quit) { + for (i = 0; code[i] != sep; i++) { + if (code[i] == '\0') { + quit = 1; + break; + } + label[i] = code[i]; + } + label[i] = '\0'; + if (strcmp(id, label) == 0) return (n); + code += (i+1); + n++; + } + + fprintf(stderr,"Syntax error: node identifier \"%s\" not found " + "in coding string \"%s\"\n", id, coding); + fprintf(stderr,"Exiting..."); + exit(0); +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE void encode( int type, char label[]) + +{ + int i, l; + + l = 0; + for (i = 0; i < type; i++) { + while (coding[l] != sep && coding[l]) l++; + l++; + } + + for (i = 0; coding[l+i] != sep; i++) { + if (coding[l+i] == '\0') break; + label[i] = coding[l+i]; + } + label[i] = '\0'; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void sprint_aligned_swStrings(swString *T1, swString *T2) +{ + int i, j, l0, l1, ltmp=0, weights; + char label[10], *a0, *a1, tmp0[20], tmp1[20]; + + weights = 0; + for (i=1; i<=T1[0].sign; i++) weights = (weights||(T1[i].weight!=0.5)); + for (i=1; i<=T2[0].sign; i++) weights = (weights||(T2[i].weight!=0.5)); + + a0 = (char *) space(alignment[0][0]*4+2); + a1 = (char *) space(alignment[0][0]*4+2); + for(i=1; i<= alignment[0][0]; i++){ + tmp0[0] = '\0'; l0=0; + if(alignment[0][i] > 0) { + encode(T1[alignment[0][i]].type, label); + if(T1[alignment[0][i]].sign > 0) { + tmp0[0] = '('; + tmp0[1] = '\0'; + } + strcat(tmp0,label); + if (weights) + sprintf(tmp0+strlen(tmp0), "%d", + (int)(2*T1[alignment[0][i]].weight)); + + if(T1[alignment[0][i]].sign < 0) strcat(tmp0, ")"); + l0 = strlen(tmp0); + } + tmp1[0]= '\0'; l1=0; + if(alignment[1][i] > 0) { + encode(T2[alignment[1][i]].type, label); + if(T2[alignment[1][i]].sign > 0) { + tmp1[0] = '('; + tmp1[1] = '\0'; + } + strcat(tmp1,label); + if (weights) + sprintf(tmp1+strlen(tmp1), "%d", + (int)(2*T2[alignment[1][i]].weight)); + + if(T2[alignment[1][i]].sign < 0) strcat(tmp1, ")"); + l1 = strlen(tmp1); + } + ltmp = MAX(l0,l1); + for (j=l0; j5~yZy0uxPbBq5*zA(>1d8j_Gq5G@2S zL>XfgsF7`%w22mwa)D9N!ojRf8YKw zbJqIr_1bGc&OZB0SXWp)$7NZ9izO}=364=A9+{J%3nW<}&J*dPJzf<1T~X{n%lV=3 z{!qtRSQYAY7kC$Rg?7E?3WZZVC%hBfx1N~oy(%a?d)iO7ObUg&Lmg)(Ne)X3bq@O; zO8-tudpvt;HiyD-Ft;w$nbIy5zzJ9fLCMbU2)f*}y}t+!bhmf4R$Uf$4+Pb;;(?wk z!oytN3^bG$ba_G@(^30`chN!bg5QIM_1=ubMV;>1C%lW_^JeVzmdU`qS%<-W`pqq4 zZamMs-~~{gkaG74?^S!?^Wq8b!d*b5^+QX0Fenfy3cEL;IZ#X4f9%zo&4C4h^1%E+ z?5}~c`K6%^pS%ge?I%OAGJjeqR_yoe-{^k=4XiEK4r=UviXhbz>! z+ugY-e){z3uMUpcwc+r3DA6Oa1G|o-eYI=-dLg{Q1EJ2@u8=o)P`nW8RB?pb-nIj= zHv*a6h3)Z{%uq*}-?LMQ^_Rq4p^l(Gty{RzHyiC7mlR|V}AqpnJ>n7g~ErtJMNNQz3DFLCz$tj>$`!@xmKvN%%6_= 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DaqB3i literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/subopt.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/subopt.c new file mode 100755 index 00000000..6d21497b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/subopt.c @@ -0,0 +1,935 @@ +/* + $Log: subopt.c,v $ + Revision 1.18 2003/10/06 08:56:45 ivo + use P->TerminalAU + + Revision 1.17 2003/08/26 09:26:08 ivo + don't modify print_energy in subopt(); use doubles instead of floats + + Revision 1.16 2001/10/01 13:50:00 ivo + sorted -> subopt_sorted + + Revision 1.15 2001/09/17 10:30:42 ivo + move scale_parameters() into params.c + returns pointer to paramT structure + + Revision 1.14 2001/08/31 15:02:19 ivo + Let subopt either write to file pointer or return a list of structures, + so we can nicely integrate it into the library + + Revision 1.13 2001/04/05 07:35:08 ivo + remove uneeded declaration of TETRA_ENERGY + + Revision 1.12 2000/10/10 08:53:20 ivo + adapted for new Turner energy parameters + supports all constraints that forbid pairs + + Revision 1.11 2000/04/08 15:56:18 ivo + with noLonelyPairs=1 will produce no structures with isolated base pairs + (Giegerich's canonical structures) + + Revision 1.10 1999/05/06 10:13:35 ivo + recalculte energies before printing if logML is set + + cosmetic changes + + Revision 1.9 1998/05/19 16:31:52 ivo + added support for constrained folding + + Revision 1.8 1998/03/30 14:44:54 ivo + cleanup of make_printout etc. + + Revision 1.7 1998/03/30 14:39:31 ivo + replaced BasePairs list with structure string in STATE + save memory by not storing (and sorting) structures + modified for use with ViennaRNA-1.2.1 + + Revision 1.6 1997/10/21 11:34:09 walter + steve update + + Revision 1.1 1997/08/04 21:05:32 walter + Initial revision + +*/ +/* + suboptimal folding - Stefan Wuchty, Walter Fontana & Ivo Hofacker + + Vienna RNA package +*/ +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "list.h" +#include "subopt.h" +#include "params.h" + +#define true 1 +#define false 0 + +#define PUBLIC +#define PRIVATE static + +/*@unused@*/ +PRIVATE char UNUSED rcsid[] = "$Id: subopt.c,v 1.18 2003/10/06 08:56:45 ivo Exp $"; + +/*Typedefinitions ---------------------------------------------------------- */ + +typedef struct { + char *structure; + LIST *Intervals; + int partial_energy; + /* int best_energy; */ /* best attainable energy */ +} STATE; + +typedef struct { + int i; + int j; +} PAIR; + +typedef struct { + int i; + int j; + int array_flag; +} INTERVAL; + + +PRIVATE void make_pair(int i, int j, STATE *state); +PRIVATE INTERVAL *make_interval (int i, int j, int ml); +/*@out@*/ PRIVATE STATE *make_state(/*@only@*/LIST *Intervals, + /*@only@*/ /*@null@*/ char *structure, + int partial_energy); +PRIVATE STATE *copy_state(STATE * state); +PRIVATE void print_state(STATE * state); +PRIVATE void UNUSED print_stack(LIST * list); +/*@only@*/ PRIVATE LIST *make_list(void); +PRIVATE void push(LIST * list, /*@only@*/ void *data); +PRIVATE void *pop(LIST * list); +PUBLIC SOLUTION *subopt (char *seq, char *sequence, int delta, FILE *fp); +PRIVATE int best_attainable_energy(STATE * state); +PRIVATE void scan_interval(int i, int j, int array_flag, STATE * state); +PRIVATE void free_interval_node(/*@only@*/ INTERVAL * node); +PRIVATE void free_state_node(/*@only@*/ STATE * node); +PRIVATE void push_back(STATE * state); +PRIVATE char* get_structure(STATE * state); +PRIVATE int compare(const void *solution1, const void *solution2); +PRIVATE void make_output(SOLUTION *SL, FILE *fp); +PRIVATE void repeat(int i, int j, STATE * state, + int part_energy, int temp_energy); + +/*Globals ------------------------------------------------------------------ */ +/* options that may be modified by RNAsubopt.c */ +int subopt_sorted=0; /* output sorted by energy */ + +#define MAXALPHA 20 /* maximal length of alphabet */ + +PRIVATE LIST *Stack; +PRIVATE int nopush; +PRIVATE int best_energy; /* best_energy = remaining energy */ + +PRIVATE int *f5; /* energy of 5 end */ +PRIVATE int *c; /* energy array, given that i-j pair */ +PRIVATE int *fML; /* multi-loop auxiliary energy array */ +PRIVATE int *fM1; /* another multi-loop auxiliary energy array */ +PRIVATE int *indx; /* index for moving in the triangle matrices c[] and f[] */ +PRIVATE short *S, *S1; + +PRIVATE char *ptype; + +PRIVATE const paramT *P; +/* extern float energy_of_struct(char *, char *); */ +extern int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1); +extern int HairpinE(int size, int type, int si1, int sj1, const char *string); +extern void export_fold_arrays(int **f5_p, int **c_p, int **fML_p, + int **fM1_p, int **indx_p, char **ptype_p); +extern int uniq_ML; + +PRIVATE int length; +PRIVATE int minimal_energy; /* minimum free energy */ +PRIVATE int element_energy; /* internal energy of a structural element */ +PRIVATE int threshold; /* minimal_energy + delta */ +PRIVATE char *sequence; +PUBLIC double print_energy = 9999; /* printing threshold for use with logML */ + + +PRIVATE void encode_seq(char *sequence) { + unsigned int i,l; + + l = strlen(sequence); + S = (short *) space(sizeof(short)*(l+1)); + S1= (short *) space(sizeof(short)*(l+1)); + /* S1 exists only for the special X K and I bases and energy_set!=0 */ + S[0] = S1[0] = (short) l; + + for (i=1; i<=l; i++) { /* make numerical encoding of sequence */ + S[i]= (short) encode_char(toupper(sequence[i-1])); + S1[i] = alias[S[i]]; /* for mismatches of nostandard bases */ + } +} + +/*---------------------------------------------------------------------------*/ +/*List routines--------------------------------------------------------------*/ +/*---------------------------------------------------------------------------*/ + +PRIVATE void +make_pair(int i, int j, STATE *state) +{ + state->structure[i-1] = '('; + state->structure[j-1] = ')'; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE INTERVAL * +make_interval(int i, int j, int array_flag) +{ + INTERVAL *interval; + + interval = lst_newnode(sizeof(INTERVAL)); + interval->i = i; + interval->j = j; + interval->array_flag = array_flag; + return interval; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +free_interval_node(INTERVAL * node) +{ + lst_freenode(node); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +free_state_node(STATE * node) +{ + free(node->structure); + if (node->Intervals) + lst_kill(node->Intervals, lst_freenode); + lst_freenode(node); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE STATE * +make_state(LIST * Intervals, + char *structure, + int partial_energy) +{ + STATE *state; + + state = lst_newnode(sizeof(STATE)); + + if (Intervals) + state->Intervals = Intervals; + else + state->Intervals = lst_init(); + if (structure) + state->structure = structure; + else { + int i; + state->structure = (char *) space(length+1); + for (i=0; istructure[i] = '.'; + } + + state->partial_energy = partial_energy; + + return state; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE STATE * +copy_state(STATE * state) +{ + STATE *new_state; + void *after; + INTERVAL *new_interval, *next; + + new_state = lst_newnode(sizeof(STATE)); + new_state->Intervals = lst_init(); + new_state->partial_energy = state->partial_energy; + /* new_state->best_energy = state->best_energy; */ + + if (state->Intervals->count) { + after = LST_HEAD(new_state->Intervals); + for ( next = lst_first(state->Intervals); next; next = lst_next(next)) + { + new_interval = lst_newnode(sizeof(INTERVAL)); + *new_interval = *next; + lst_insertafter(new_state->Intervals, new_interval, after); + after = new_interval; + } + } + new_state->structure = strdup(state->structure); + if (!new_state->structure) nrerror("out of memory"); + return new_state; +} + +/*---------------------------------------------------------------------------*/ + +/*@unused @*/ PRIVATE void +print_state(STATE * state) +{ + INTERVAL *next; + + if (state->Intervals->count) + { + printf("%d intervals:\n", state->Intervals->count); + for (next = lst_first(state->Intervals); next; next = lst_next(next)) + { + printf("[%d,%d],%d ", next->i, next->j, next->array_flag); + } + printf("\n"); + } + printf("partial structure: %s\n", state->structure); + printf("\n"); + printf(" partial_energy: %d\n", state->partial_energy); + /* printf(" best_energy: %d\n", state->best_energy); */ + (void) fflush(stdout); +} + +/*---------------------------------------------------------------------------*/ + +/*@unused @*/ PRIVATE void +print_stack(LIST * list) +{ + void *rec; + + printf("================\n"); + printf("%d states\n", list->count); + for (rec = lst_first(list); rec; rec = lst_next(rec)) + { + printf("state-----------\n"); + print_state(rec); + } + printf("================\n"); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE LIST * +make_list(void) +{ + return lst_init(); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +push(LIST * list, void *data) +{ + nopush = false; + lst_insertafter(list, data, LST_HEAD(list)); +} + +/* PRIVATE void */ +/* push_stack(STATE *state) { */ /* keep the stack sorted by energy */ +/* STATE *after, *next; */ +/* nopush = false; */ +/* next = after = LST_HEAD(Stack); */ +/* while ( next = lst_next(next)) { */ +/* if ( next->best_energy >= state->best_energy ) break; */ +/* after = next; */ +/* } */ +/* lst_insertafter(Stack, state, after); */ +/* } */ + +/*---------------------------------------------------------------------------*/ + +PRIVATE void * +pop(LIST * list) +{ + void *data; + + data = lst_deletenext(list, LST_HEAD(list)); + return data; +} + +/*---------------------------------------------------------------------------*/ +/*auxiliary routines---------------------------------------------------------*/ +/*---------------------------------------------------------------------------*/ + +PRIVATE int +best_attainable_energy(STATE * state) +{ + /* evaluation of best possible energy attainable within remaining intervals */ + + register int sum; + INTERVAL *next; + + sum = state->partial_energy; /* energy of already found elements */ + + for (next = lst_first(state->Intervals); next; next = lst_next(next)) + { + if (next->array_flag == 0) + sum += f5[next->j]; + else if (next->array_flag == 1) + sum += fML[indx[next->j] + next->i]; + else if (next->array_flag == 2) + sum += c[indx[next->j] + next->i]; + else if (next->array_flag == 3) + sum += fM1[indx[next->j] + next->i]; + } + + return sum; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +push_back(STATE * state) +{ + push(Stack, copy_state(state)); + return; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE char* +get_structure(STATE * state) +{ + char* structure; + + structure = strdup(state->structure); + return structure; +} + +/*---------------------------------------------------------------------------*/ +PRIVATE int +compare(const void *solution1, const void *solution2) +{ + if (((SOLUTION *) solution1)->energy > ((SOLUTION *) solution2)->energy) + return 1; + if (((SOLUTION *) solution1)->energy < ((SOLUTION *) solution2)->energy) + return -1; + return strcmp(((SOLUTION *) solution1)->structure, + ((SOLUTION *) solution2)->structure); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void make_output(SOLUTION *SL, FILE *fp) /* prints stuff */ +{ + SOLUTION *sol; + + for (sol = SL; sol->structure!=NULL; sol++) + fprintf(fp, "%s %6.2f\n", sol->structure, sol->energy); +} + +/*---------------------------------------------------------------------------*/ +/* start of subopt backtracking ---------------------------------------------*/ +/*---------------------------------------------------------------------------*/ + +PUBLIC SOLUTION *subopt(char *seq, char *structure, int delta, FILE *fp) +{ + STATE *state; + LIST *Intervals; + INTERVAL *interval; + SOLUTION *SolutionList; + + unsigned long max_sol = 128, n_sol = 0; + + int maxlevel, count, partial_energy, old_dangles; + double structure_energy, min_en, eprint; + char* struc; + + sequence = seq; + length = strlen(sequence); + + struc = (char *) space(sizeof(char)*(length+1)); + if (fold_constrained) strncpy(struc, structure, length); + /* do mfe folding to get fill arrays and get ground state energy */ + /* in case dangles is neither 0 or 2, set dangles=2 while folding */ + old_dangles = dangles; + if ((dangles!=0) && (dangles != 2)) dangles = 2; + + uniq_ML = 1; + initialize_fold(length); + min_en = fold(sequence, struc); + export_fold_arrays(&f5, &c, &fML, &fM1, &indx, &ptype); + dangles = old_dangles; + /* re-evaluate in case we're using logML etc */ + min_en = energy_of_struct(sequence, struc); + free(struc); + eprint = print_energy + min_en; + if (fp) + fprintf(fp, "%s %6d %6d\n", sequence, (int) (-0.1+100*min_en), delta); + + make_pair_matrix(); + encode_seq(sequence); + P = scale_parameters(); + + /* Initialize ------------------------------------------------------------ */ + + maxlevel = 0; + count = 0; + partial_energy = 0; + + /* Initialize the stack ------------------------------------------------- */ + + minimal_energy = f5[length]; + threshold = minimal_energy + delta; + + Stack = make_list(); /* anchor */ + Intervals = make_list(); /* initial state: */ + interval = make_interval(1, length, 0); /* interval [1,length,0] */ + push(Intervals, interval); + state = make_state(Intervals, NULL, partial_energy); + /* state->best_energy = minimal_energy; */ + push(Stack, state); + + /* SolutionList stores the suboptimal structures found */ + + SolutionList = (SOLUTION *) space(max_sol*sizeof(SOLUTION)); + + /* end initialize ------------------------------------------------------- */ + + + while (1) { /* forever, til nothing remains on stack */ + + maxlevel = (Stack->count > maxlevel ? Stack->count : maxlevel); + + if (LST_EMPTY (Stack)) /* we are done! clean up and quit */ + { + /* fprintf(stderr, "maxlevel: %d\n", maxlevel); */ + + lst_kill(Stack, free_state_node); + + SolutionList[n_sol].structure = NULL; /* NULL terminate list */ + + if (subopt_sorted) { + /* sort structures by energy */ + qsort(SolutionList, n_sol, sizeof(SOLUTION), compare); + + if (fp) make_output(SolutionList, fp); + } + + break; + } + + /* pop the last element ---------------------------------------------- */ + + state = pop(Stack); /* current state to work with */ + + if (LST_EMPTY(state->Intervals)) + { + /* state has no intervals left: we got a solution */ + + count++; + structure = get_structure(state); + structure_energy = state->partial_energy / 100.; + +#ifdef CHECK_ENERGY + structure_energy = energy_of_struct(sequence, structure); + + if (!logML) + if ((double) (state->partial_energy / 100.) != structure_energy) { + fprintf(stderr, "%s %6.2f %6.2f\n", structure, + state->partial_energy / 100., structure_energy ); + exit(1); + } +#endif + if (logML || (dangles==1) || (dangles==3)) { /* recalc energy */ + structure_energy = energy_of_struct(sequence, structure); + } + + if (structure_energy>eprint) { + free(structure); + } else { + if (!subopt_sorted && fp) { + /* print and forget */ + fprintf(fp, "%s %6.2f\n", structure, structure_energy); + free(structure); + } + else { + /* store solution */ + if (n_sol+1 == max_sol) { + max_sol *= 2; + SolutionList = (SOLUTION *) + xrealloc(SolutionList, max_sol*sizeof(SOLUTION)); + } + SolutionList[n_sol].energy = structure_energy; + SolutionList[n_sol++].structure = structure; + } + } + } + else { + /* get (and remove) next interval of state to analyze */ + + interval = pop(state->Intervals); + + scan_interval(interval->i, interval->j, interval->array_flag, state); + + free_interval_node(interval); /* free the current interval */ + } + + free_state_node(state); /* free the current state */ + } /* end of while (1) */ + + /* free arrays left over from fold() */ + free(S); free(S1); + free_arrays(); + if (fp) { /* we've printed everything -- free solutions */ + SOLUTION *sol; + for (sol=SolutionList; sol->structure != NULL; sol++) + free(sol->structure); + free(SolutionList); + SolutionList = NULL; + } + + return SolutionList; +} + +/*---------------------------------------------------------------------------*/ +/* Definitions---------------------------------------------------------------*/ +/* these have to identical to defines in fold.c */ +#define NEW_NINIO 1 /* use new asymetry penalty */ +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +scan_interval(int i, int j, int array_flag, STATE * state) +{ + /* real backtrack routine */ + + /* array_flag = 0: trace back in f5-array */ + /* array_flag = 1: trace back in fML-array */ + /* array_flag = 2: trace back in repeat() */ + /* array_flag = 3: trace back in fM1-array */ + + STATE *new_state, *temp_state; + INTERVAL *new_interval; + register int k, fi, cij; + register int type; + + best_energy = best_attainable_energy(state); /* .. on remaining intervals */ + nopush = true; + + if ((i > 1) && (!array_flag)) + nrerror ("Error while backtracking!"); + + if (j < i + TURN + 1) { /* minimal structure element */ + if (nopush) + push_back(state); + return; + } + + /* 13131313131313131313131313131313131313131313131313131313131313131313131 */ + + if (array_flag == 3 || array_flag == 1) { + /* array_flag = 3: interval i,j was generated during */ + /* a multiloop decomposition using array fM1 in repeat() */ + /* or in this block */ + + /* array_flag = 1: interval i,j was generated from a */ + /* stack, bulge, or internal loop in repeat() */ + /* or in this block */ + + if (array_flag == 3) + fi = fM1[indx[j-1] + i] + P->MLbase; + else + fi = fML[indx[j-1] + i] + P->MLbase; + + if (fi + best_energy <= threshold) { + /* no basepair, nibbling of 3'-end */ + + new_state = copy_state(state); + new_interval = make_interval(i, j-1, array_flag); + push(new_state->Intervals, new_interval); + new_state->partial_energy += P->MLbase; + /* new_state->best_energy = fi + best_energy; */ + push(Stack, new_state); + } + + type = ptype[indx[j]+i]; + + if (type) { /* i,j may pair */ + + element_energy = P->MLintern[type]; + + if ( type && dangles ) { /* dangling ends */ + if (i > 1) + element_energy += P->dangle5[type][S1[i-1]]; + if (j < length) + element_energy += P->dangle3[type][S1[j+1]]; + } + + cij = c[indx[j] + i] + element_energy; + if (cij + best_energy <= threshold) + repeat(i, j, state, element_energy, 0); + } + } /* array_flag == 3 || array_flag == 1 */ + + /* 11111111111111111111111111111111111111111111111111111111111111111111111 */ + + if (array_flag == 1) { + /* array_flag = 1: interval i,j was generated from a */ + /* stack, bulge, or internal loop in repeat() */ + /* or in this block */ + + for ( k = i+TURN+1 ; k <= j-1-TURN ; k++) { + /* Multiloop decomposition if i,j contains more than 1 stack */ + + type = ptype[indx[j]+k+1]; + if (type==0) continue; + + element_energy = P->MLintern[type]; + if (dangles) + element_energy += P->dangle3[type][S1[j+1]] + P->dangle5[type][S1[k]]; + + + if (fML[indx[k]+i] + c[indx[j] + k+1] + + element_energy + best_energy <= threshold) { + temp_state = copy_state (state); + new_interval = make_interval (i, k, 1); + push (temp_state->Intervals, new_interval); + repeat(k+1, j, temp_state, element_energy, fML[indx[k]+i]); + free_state_node(temp_state); + } + } + + for (k = i ; k <= j-1-TURN; k++) { + /* Multiloop decomposition if i,j contains only 1 stack */ + type = ptype[indx[j]+k+1]; + if (type==0) continue; + + element_energy = P->MLintern[type] + P->MLbase*(k-i+1); + if (dangles) + element_energy += P->dangle3[type][S1[j+1]] + P->dangle5[type][S1[k]]; + + if (c[indx[j]+k+1] + element_energy + best_energy <= threshold) + repeat(k+1, j, state, element_energy, 0); + } + } /* array_flag == 1 */ + + /* 2222222222222222222222222222222222222222222222222222222222222222222222 */ + + if (array_flag == 2) + { + /* array_flag = 2: interval i,j was generated from a */ + /* stack, bulge, or internal loop in repeat() */ + + repeat(i, j, state, 0, 0); + + if (nopush) + if (!noLonelyPairs) + fprintf(stderr, "Oops, no solution in repeat!\n"); + return; + } + + /* 0000000000000000000000000000000000000000000000000000000000000000000000 */ + + if (array_flag == 0) + { + /* array_flag = 0: interval i,j was found while */ + /* tracing back through f5-array and c-array */ + /* or within this block */ + + if (f5[j-1] + best_energy <= threshold) { + /* no basepair, nibbling of 3'-end */ + + new_state = copy_state(state); + new_interval = make_interval(i, j-1 , 0); + push(new_state->Intervals, new_interval); + /* new_state->best_energy = f5[j-1] + best_energy; */ + push(Stack, new_state); + } + + for (k = j-TURN-1; k > 1; k--) { + + type = ptype[indx[j]+k]; + if (type==0) continue; + + /* k and j pair */ + if (dangles) { + element_energy = P->dangle5[type][S1[k - 1]]; + if (j < length) + element_energy += P->dangle3[type][S1[j+1]]; + } + else /* no dangles */ + element_energy = 0; + + if (type>2) + element_energy += P->TerminalAU; + + if (f5[k-1] + c[indx[j]+k] + element_energy + best_energy <= threshold) + { + temp_state = copy_state(state); + new_interval = make_interval(1, k-1, 0); + push(temp_state->Intervals, new_interval); + repeat(k, j, temp_state, element_energy, f5[k-1]); + free_state_node(temp_state); + } + } + type = ptype[indx[j]+1]; + if (type) { + if (dangles && (j < length)) { + element_energy = P->dangle3[type][S1[j+1]]; + } + else + element_energy = 0; + + if (type>2) + element_energy += P->TerminalAU; + + if (c[indx[j]+1] + element_energy + best_energy <= threshold) + repeat(1, j, state, element_energy, 0); + } + } /* array_flag == 0 */ + + if (nopush) + push_back(state); + return; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void +repeat(int i, int j, STATE * state, int part_energy, int temp_energy) +{ + /* routine to find stacks, bulges, internal loops and multiloops */ + /* within interval closed by basepair i,j */ + + STATE *new_state; + INTERVAL *new_interval; + + register int k, p, q, energy, new; + register int mm; + register int no_close, no_close_2, type, type_2; + int rt; + + no_close_2 = 0; + + type = ptype[indx[j]+i]; + if (type==0) fprintf(stderr, "repeat: Warning: %d %d can't pair\n", i,j); + + no_close = (((type == 3) || (type == 4)) && no_closingGU); + + if (noLonelyPairs) /* always consider the structure with additional stack */ + if ((i+TURN+2Intervals, new_interval); + energy = LoopEnergy(0, 0, type, rtype[type_2], + S1[i+1],S1[j-1],S1[i+1],S1[j-1]); + new_state->partial_energy += part_energy; + new_state->partial_energy += energy; + /* new_state->best_energy = new + best_energy; */ + push(Stack, new_state); + if (i==1 || state->structure[i-2]!='(' || state->structure[j]!=')') + /* adding a stack is the only possible structure */ + return; + } + + best_energy += part_energy; /* energy of current structural element */ + best_energy += temp_energy; /* energy from unpushed interval */ + + for (p = i + 1; p <= MIN2 (j-2-TURN, i+MAXLOOP+1); p++) { + int minq = j-i+p-MAXLOOP-2; + if (minq= minq; q--) { + if ((noLonelyPairs) && (p==i+1) && (q==j-1)) continue; + + type_2 = ptype[indx[q]+p]; + if (type_2==0) continue; + + if (no_closingGU) + if (no_close||(type_2==3)||(type_2==4)) + if ((p>i+1)||(qIntervals, new_interval); + new_state->partial_energy += part_energy; + new_state->partial_energy += energy; + /* new_state->best_energy = new + best_energy; */ + push(Stack, new_state); + } + } /* end of q-loop */ + } /* end of p-loop */ + + mm = P->MLclosing + P->MLintern[type]; + rt = rtype[type]; + + for (k = i + 1 + TURN; k <= j - 1 - TURN; k++) { + /* multiloop decomposition */ + + element_energy = mm; + if (dangles) + element_energy += P->dangle3[rt][S1[i+1]] + P->dangle5[rt][S1[j-1]]; + + if (fML[indx[k] + i+1] + fM1[indx[j-1] + k+1] + + element_energy + best_energy <= threshold) + { + INTERVAL *interval1, *interval2; + + new_state = copy_state(state); + interval1 = make_interval(i+1, k, 1); + interval2 = make_interval(k+1, j-1, 3); + if (k-i+1 < j-k-2) { /* push larger interval first */ + push(new_state->Intervals, interval1); + push(new_state->Intervals, interval2); + } else { + push(new_state->Intervals, interval2); + push(new_state->Intervals, interval1); + } + make_pair(i, j, new_state); + new_state->partial_energy += part_energy; + new_state->partial_energy += element_energy; + /* new_state->best_energy = fML[indx[k] + i+1] + fM1[indx[j-1] + k+1] + + element_energy + best_energy; */ + push(Stack, new_state); + } + } /* end of k-loop */ + + + if (no_close) energy = FORBIDDEN; + else + energy = HairpinE(j-i-1, type, S1[i+1], S1[j-1], sequence+i-1); + + if (energy + best_energy <= threshold) { + /* hairpin structure */ + + new_state = copy_state(state); + make_pair(i, j, new_state); + new_state->partial_energy += part_energy; + new_state->partial_energy += energy; + /* new_state->best_energy = + hairpin[unpaired] + element_energy + best_energy; */ + push(Stack, new_state); + } + + best_energy -= part_energy; + best_energy -= temp_energy; + return; +} + +/*---------------------------------------------------------------------------*/ +/* Well, that is the end!----------------------------------------------------*/ +/*---------------------------------------------------------------------------*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/subopt.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/subopt.o new file mode 100755 index 0000000000000000000000000000000000000000..35b4c5791a8f370a75126d80a7a12dccab42aa6f GIT binary patch literal 50096 zcmeHw3v^V~_4mDV0}K$D1frsXjuPb^5?+Rfn!p4m5;TxWKm|jXOh_~&A(;RwLL><~ z4gqS>qQbw_wic}YwAKPrA3Ox4T8nS{w<=b6K8g?l4M{msw04^&iCYy{++XYq17eq_DkZ{6#U>t4>FouP^7NCD z?+PN->8Eld{{)=|XdRcc8u%8=t|GylR8CGC-gzpig!B$^6J^KPdOsvjd=p zACO}Ok#PDcP;RKGpC5US&c1ZFKe9hRdYd~pnwOFr@ujCkJ*`I?#{xucweHQ2B&CNN z3L?j_3x3cZx=@~;g8dj!5Dlk$p)*4dY%GY@yYrh5xrONC6E-?V@J9~#qj^StbR|@c zeBqD0n;&`CAF-l&?#MLB?~k02T|*}wY&_6$Yb+LXym$QeijC3?qQ}By{^(ryVc|g4%(dBMG=))++OZ%H=VljX8a#1642pxZX7X}Ob`_hx**^L1RM0Zcd^UE*T z4LZa;8T*!}`J>CgfvZ`TURYTm&tx0E5^0gFg6(1kx)bE7QY~g7k79 zSa_iyJ|Lci>i%dTeP}dkqhCg{dCI@p^Gs4o>t5g~^t8l)DGJnKUwQy_Zf>`lPnpZl zjt;_-(6;q$j}NW_f50c~bK{^jL0NUXpL(DWB(>Q?VC(6TkDUyA^nmZP;7Bwz}ByzOff_V~50*GPvTC zHppvzCEVLL5!&~(JP(SKr3!){l98rHleYQHcC^&Ul-5tfPx_*L&>VTKN5bhokRQlv z-Rrq$fAeX}vuSV7quWhS>vRi@cRI<_ayby_moN$QMZWff4TkzW&-$jqfIkRC!7XQ^ z$*m}IDxiy8aD5<{$DJQMh+JpDf`yT!bP=$TgSIDywQS|0No&k@OE`J5`1EY(1L1^? zRYI@ZXMG=w!QiQbau~)S2F1MgJHJDYK>EDMyFM5ZH$!oc3-pl1yYMPREp%~S>;->x zg}eP5kRmDoR!)I!O-=Df-Z0xEQ&ZaCgzISFwx2@a15X%z?MolnytlI(+pfTY5rmFW zcfgBbU-YSsQ_?KMXYHO3r{)7mAfYarb`P4Sxjkv(Tb^}0z;XWIe$fl49`?5-HDO<} zku`Q0f@d6#fE*D)nFylu7oLf{H3GD0t2B?FEjSOv4(7&QB%uL}6ER4Aku$!Cpju<$ zJloVO({udN>3+|%ffX*{LO;ZFHk5rU&iF0Vpyl?rdK-q-@}m`ykK4v&M#iJ!D+zrw5+)41pQ*YfnoL z&_Is3Hs4tW#pwE9K_^B)hJgPI<@kprx#Ic-x$|=uJQYX3w1EGC}G*jnMu;vt~3R%Pl z(+rGL7!H^yp2I=#aeD|Z+GFD5_GM7yF(K^uH(?#oveY7YkOp(s*I6+f-PfJ*2Qj)K zQm%9PAT7HE1?||QT9`L-&@nKKCdaaCpowO1hv{i~Ps}Hf;bDEyv~s|ip`O+k1qA(X znlfORr}b$lcB}?p2y3-wK-cAb({Tns3IXsqgurm2I&@dW#4YZQQ>SCG$iK*;kVEB5F7*z=VCI(C7U&?RO5i+l-FV5MIUTp0cH{9xrmKg?p;O*jI9$b_?8VYIC< zBO++z0syQoN|3@^?}PL&=QNoOgx}?yk7Es{zI*n;BJMkv=bpW-`#io^WyDHBJj;J3 zin&i>gSor$Q;>U*5*Brq8TQKHvxt~rMa?fg*TI_P#221aO8FI@eo5)@AtoI^1VW+l zg=gOLz)+ArG@SK?=UUMLoQdX%29%6bn6(#p#q}>dBc%ytBFp-;^@ykSRxv#ttcW~< z>KU)S)URK)(pPB8(o(E5tfm~QAUX=Uvp$^#1Gn{hP%rCKXfgL0Zt|$V zZJZF8?|JkPG%wn~eBckJM!SOo&HIvI85RHqxaGgemUmM+e;R%1j~vFt=@lk#n`h=i z*?c?lo+wA&^D7}jD)}a!uJA>&A+gfMioD2ehG*?Lkn=??e-L#9$->+`uO)4iWk^Z$ zNa%xKVGa>o?e_v59gp?kjv;dJS=6mP^`FRa0`g4zTDUIO)v}4!PhoNEX;}%e;D<%N zjJeohaWU%%tZ|Pg`=gdW_;PIDp`?_I$s%S}{=*KmcMnfX!N%G%P_E%-)xi`w9S_3= ze>7VN`y$sf99HMFMgq-Xne>I{2B9?MobE7C1P#kWPs`I#Y(8aqTAl!+!jl2(P0t;N zfp%6(o=tH3BZC(Q&wfv9xCgd2KRweQJK&!@KRw&ia$zq6Li@VsF-v7)BF@44icJ5$ zV@YsZk>dW+lbW1T07*ILOUyT7o{o;j4F6+jto;@=8zeTk-|$5*gk`CxWfaVs?Tdst zed&G_>GwsmbD`OkXik#2Lx|3CL+{fdZKQ~vA3xh4EPN(I5Fn;NpJnkf-HK za8WeJ-MTmYrs({BC^w&SZS=I<169Bbjeqh7ujZ*d+TBXJiwERpYv7vWk76{Yc{Xf9 zYeQr|jVtYE)36jd3PF9)FIwJs7!bgk_a?>ueDfE_kJ#Y_Grqie=_tf`E%;9Evlw{I z2VGM=&rBK7Ui5h^2Gq(CW0^+ua@%Gk z!7U4TxEe}$6>bamRgX+_wNjv;9i3ldoGs&5d+*^KywvsOP2S4}8h>ot?g==iMWr+wu z;knqeRp}J)`N21FiCcIELS?7lJZi1G0~fWD7lvh;T)5qK5%FII%#|);j<(!^OJ7q2 zu+&PVMA<)mxA;1V2BH0BVOW(2BuoRhrj1_ zWFKUopPtryJgNCR)3g2)2o&3*BEKH*9eY7s8VbfolHb1y!B};mLFXOn=FUg z3r=7*6qbTzRa)dd=>^yjfxF|VZ~OP{dw`<=vfCF>3oO&wT%HYY!AfmrFlmS9nSx9c z<7o@TlTXH39Z$g#~X8 zip5rQ;D)MFxuHU~LVx5Fp_|y!k#)F_TX3xo13kB`G>PtyC&P#lk+wL509nbpnxfWfbl$=b|WNkH$+afWv#rc zUN2J1DYL`K@vb4L8&<@pd(OCei4bavW~#paXcTjJJBR_WM6^Mo-^= z*rSKkgF9>41q?m7KTg^%5}FUjD~zf3B~Sqe(=R~?8i{U$-+?H=qA&6tAh12iYqS}gGOG~ zN4VG?fRPWIe#aumacAKI_w7)EB{y{VR=ccN~t3myYR>(y*`BLbuR0(9f(_ zWKVZ~?DTXvbj9gn`}t7p*o~uK=GLqukX>?zXp9=wNr z21k^VBI}V`$|Gq$Y$h3+Nw|V+KHZr_FrMze>cftIh?^R= zXvaHHjBmtVh}w<7LR4=AXCJ!}XU&O?+yPQ4V@`8--10>%2E24M-Ekm?>8{SWzD1Q` zqJ-tLAy%{46f9o;%ZHdCsg_D3gl!}`PzOA)ef_|m;(_|92jeQnG|S_%de-$&<;3Zn zYNmAWXQrB$^zGl<>U(})!*HE#SbZn;p4>aXKj@ndh2FidfLxUXq+62RJVtMExqE-p z?2in{4;Jkst9HxppAB~_Ze%lzo|hUZsu#;OjNZftGLSFX1S!bU=OW-74ORMH3LWyG za2A~cRoqf5tdc6Ob(hWd6V;$={WF9*hz?24@1JV+GjpK#Y2EC)E-0Qg&h8)<&+cs& z!|5DAsR2X>sG@`*X!Tr05ERdYB3a4>#q*USNEoOz16K#d2?U-ChzAUYjb4~R_OrEz zie9^7w;{=_$wkx_RlHd6p!&c=9fzue9r1>d9w!G{yhH_^ikJ3=kmv`2G=zFg?F=O& zQE`|f9}O_PH<%x7IRd3#nJkRsCLqKB#pa}%QHGr@(DWt_q+Pr#iqu7>?7ZHt2>| zjkRDGIr`oDK(~{CeL*lLy`BwMMCNh#5GT_uPA*wWBCxvzyCqfCgpH(bvO+f@!o8si zL`ZTYlJa7YZtfp*!R#(BchC4GAl-9C!7$$Ho*~j~k7RQZN*FA&ZjV&6O%&boYCkHb z$YOsg4v@t(Dtcw{EGiC_#j~lHDU0V&FN1D^2Xbo;MWqFi|8&KBZHB`

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zwZE({>(BecBN2c@?{6mI%+LF`z6AXIz6bO3KBxMghN=(8yUkDgFkYced|c&d_(Cct z@_UoU&;H$};cS;g{yL`dvtJU~pXG7C*v^UUnaFO5>_fv|_={;&k!kcJ(}>e@Aa0!g EZ!jWRnE(I) literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/treedist.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/treedist.c new file mode 100755 index 00000000..2473e303 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/treedist.c @@ -0,0 +1,657 @@ +/* + Tree edit distances for RNA secondary structures + Walter Fontana, Ivo L Hofacker, Peter F Stadler + Vienna RNA Package +*/ +/* Last changed Time-stamp: <97/10/27 15:23:48 ivo> */ + +#include +#include +#include +#include +#include "edit_cost.h" +#include "dist_vars.h" +#include "utils.h" +static char rcsid[] = "$Id: treedist.c,v 1.3 1997/11/03 10:39:43 ivo Rel $"; + +#define PRIVATE static +#define PUBLIC + +#define MNODES 4000 /* Maximal number of nodes for alignment */ + +PUBLIC Tree *make_tree(char *struc); +PUBLIC float tree_edit_distance(Tree *T1, Tree *T2); +PUBLIC void print_tree(Tree *t); +PUBLIC void free_tree(Tree *t); + + +PRIVATE void tree_dist(int i, int j); +PRIVATE int edit_cost(int i, int j); +PRIVATE int *make_keyroots(Postorder_list *pl); +PRIVATE void sort(int n, int *ra); +PRIVATE Postorder_list *make_postorder_list(char *struc); +PRIVATE int decode(char *id); +PRIVATE int number_of_nodes(char *struc); +PRIVATE void encode(int type, char *label); +PRIVATE void print_keyroots(int *keyroots); +PRIVATE void print_postorder_list(Postorder_list *pl); +PRIVATE void backtracking(void); +PRIVATE void sprint_aligned_trees(void); + + +PRIVATE Tree *tree1, *tree2; +PRIVATE int **tdist; /* contains distances between subtrees */ +PRIVATE int **fdist; /* contains distances between forests */ +PRIVATE int *alignment[2]; /* contains numeric information on the alignment: + alignment[0][p], aligment[1][p] are aligned postions. + INDELs have one 0. + alignment[0][0] contains the length of the alignment. */ + +/*---------------------------------------------------------------------------*/ + +PUBLIC float tree_edit_distance(Tree *T1, Tree *T2) +{ + int i1,j1,i,j, dist; + int n1, n2; + + if (cost_matrix==0) EditCost = &UsualCost; + else EditCost = &ShapiroCost; + + n1 = T1->postorder_list[0].sons; + n2 = T2->postorder_list[0].sons; + + tdist = (int **) space(sizeof(int *) * (n1+1)); + fdist = (int **) space(sizeof(int *) * (n1+1)); + for (i=0; i<=n1; i++) { + tdist[i] = (int *) space(sizeof(int) * (n2+1)); + fdist[i] = (int *) space(sizeof(int) * (n2+1)); + } + + tree1 = T1; tree2 = T2; + + for (i1 = 1; i1 <= T1->keyroots[0]; i1++) { + i = T1->keyroots[i1]; + for (j1 = 1; j1 <= T2->keyroots[0]; j1++) { + j = T2->keyroots[j1]; + + tree_dist(i,j); + } + } + + if (edit_backtrack) { + + if ((n1>MNODES)||(n2>MNODES)) nrerror("tree too large for alignment"); + + alignment[0] = (int *) space((n1+1)*sizeof(int)); + alignment[1] = (int *) space((n2+1)*sizeof(int)); + + backtracking(); + sprint_aligned_trees(); + free(alignment[0]); + free(alignment[1]); + } + dist = tdist[n1][n2]; + for (i=0; i<=n1; i++) { + free(tdist[i]); + free(fdist[i]); + } + free(tdist); + free(fdist); + + return (float) dist; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void tree_dist(int i, int j) +{ + int li,lj,i1,j1,i1_1,j1_1,li1_1,lj1_1,f1,f2,f3,f; + int cost, lleaf_i1, lleaf_j1; + + fdist[0][0] = 0; + + li = tree1->postorder_list[i].leftmostleaf; + lj = tree2->postorder_list[j].leftmostleaf; + + for (i1 = li; i1 <= i; i1++) { + i1_1 = (li == i1 ? 0 : i1-1); + fdist[i1][0] = fdist[i1_1][0] + edit_cost(i1, 0); + } + + for (j1 = lj; j1 <= j; j1++) { + j1_1 = (lj == j1 ? 0 : j1-1); + fdist[0][j1] = fdist[0][j1_1] + edit_cost(0, j1); + } + + for (i1 = li; i1 <= i; i1++) { + + lleaf_i1 = tree1->postorder_list[i1].leftmostleaf; + li1_1 = (li > lleaf_i1-1 ? 0 : lleaf_i1-1); + i1_1 = (i1 == li ? 0: i1-1); + cost = edit_cost(i1, 0); + + for (j1 = lj; j1 <= j; j1++) { + + lleaf_j1 = tree2->postorder_list[j1].leftmostleaf; + j1_1 = (j1 == lj ? 0: j1-1); + + f1 = fdist[i1_1][j1] + cost; + f2 = fdist[i1][j1_1] + edit_cost(0, j1); + + f = f1 < f2 ? f1 : f2; + + if (lleaf_i1 == li && lleaf_j1 == lj) { + + f3 = fdist[i1_1][j1_1] + edit_cost(i1, j1); + + fdist[i1][j1] = f3 < f ? f3 : f; + + tdist[i1][j1] = fdist[i1][j1]; /* store in array permanently */ + } + else { + lj1_1 = (lj > lleaf_j1-1 ? 0 : lleaf_j1-1); + + f3 = fdist[li1_1][lj1_1] + tdist[i1][j1]; + + fdist[i1][j1] = f3 < f ? f3 : f; + } + } + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int edit_cost(int i, int j) +{ + int c, diff, cd, min, a, b; + + c = (*EditCost)[tree1->postorder_list[i].type][tree2->postorder_list[j].type]; + + diff = abs((a=tree1->postorder_list[i].weight) - (b=tree2->postorder_list[j].weight)); + + min = (a < b ? a: b); + if (min == a) cd = (*EditCost)[0][tree2->postorder_list[j].type]; + else cd = (*EditCost)[0][tree1->postorder_list[i].type]; + + return (c * min + cd * diff); + +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC Tree *make_tree(char *struc) +{ + Tree *tree; + + tree = (Tree *) space(sizeof(Tree)); + + tree->postorder_list = make_postorder_list(struc); + tree->keyroots = make_keyroots(tree->postorder_list); + + return (tree); +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE int *make_keyroots(Postorder_list *pl) +{ + int i, k, keys; + int *keyroots; + + keyroots = (int *) space(sizeof(int)*(pl[0].sons+1)); + keys = 0; + + for (i = 1; i <= pl[0].sons; i++) { + if (!pl[i].sons) { + + /* leaf */ + + k = pl[0].sons; + while (pl[k].leftmostleaf != i) k--; + keyroots[++keys] = k; + } + } + + sort(keys, keyroots); + keyroots[0] = keys; + + return (keyroots); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void sort(int n, int *ra) /* heap sort, indices are 1..n !!! */ +{ + int l,j,ir,i; + int rra; + + if (n == 1) return; + + l = (n >> 1)+1; + ir = n; + for (;;) { + if (l > 1) + rra = ra[--l]; + else { + rra = ra[ir]; + ra[ir] = ra[1]; + if (--ir == 1) { + ra[1] = rra; + return; + } + } + i = l; + j = l << 1; + while (j <= ir) { + if (j < ir && ra[j] < ra[j+1]) ++j; + if (rra < ra[j]) { + ra[i] = ra[j]; + j += (i = j); + } + else j = ir+1; + } + ra[i] = rra; + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE Postorder_list *make_postorder_list(char *struc) + + /* + Convention for structure representation "struc": + Nodes are one pair of matching parentheses, with the type and possibly + a weight of the node immediately preceding the closing parentheses. + + Types: + + U....unpaired + P....paired + H....hairpin loop + B....bulge loop + I....internal loop + M....multiloop + S....stack + R....virtual root + + Example: + + .((..(((...)))..((..)))). in usual notation becomes: + + full tree: + ((U)(((U)(U)((((U)(U)(U)P)P)P)(U)(U)(((U)(U)P)P)P)P)(U)R) + HIT: + ((U1)((U2)((U3)P3)(U2)((U2)P2)P2)(U1)R) + Shapiro: + (((((H)S)((H)S)M)S)R) + + */ +{ + int paren, i, l, order, local_order, w, sons, count; + int n_nodes, p; + char id[100]; + Postorder_list *pl; + int match_pos[MNODES], match_order[MNODES]; + + + n_nodes = number_of_nodes(struc); + if (n_nodes>MNODES) nrerror("structure too long in make_postorder_list"); + pl = (Postorder_list *) space(sizeof(Postorder_list)*(n_nodes+1)); + pl[0].sons = n_nodes; + + paren = 1; + match_pos[paren] = 0; + match_order[paren] = 0; + + i = 1; + l = 0; + order = 0; + + while (paren) { + switch (struc[i]) { + case '(': + match_pos[++paren] = i; + match_order[paren] = order; + break; + case ')': + order++; + id[l] = '\0'; + l = 0; + while (isalpha((int) id[l])) l++; + if (id[l]) sscanf(id+l, "%d", &w); + else w = 1; + id[l] = '\0'; + pl[order].type = decode(id); + pl[order].weight = w; + pl[order].leftmostleaf = match_order[paren]+1; + + sons = count = 0; + local_order = match_order[paren]; + for (p = match_pos[paren]+1; p < i; p++) { + if (struc[p] == '(') count++; + else if (struc[p] == ')') { + local_order++; + if (count == 1) { + sons++; + pl[local_order].father = order; + } + count--; + } + } + + pl[order].sons = sons; + paren--; + l = 0; + break; + default: + id[l++] = struc[i]; + break; + } + i++; + } + + return (pl); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int decode(char *id) +{ + int n, quit, i; + char label[100], *code; + + n = 0; + + quit = 0; + code = coding; + + while (!quit) { + for (i = 0; code[i] != sep; i++) { + if (code[i] == '\0') { + quit = 1; + break; + } + label[i] = code[i]; + } + label[i] = '\0'; + if (strcmp(id, label) == 0) return (n); + code += (i+1); + n++; + } + + fprintf(stderr,"Syntax error: node identifier \"%s\" not found " + "in coding string \"%s\"\n", id, coding); + fprintf(stderr, "Exiting..."); + exit(0); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void encode(int type, char label[]) +{ + int i, l; + + l = 0; + for (i = 0; i < type; i++) { + while (coding[l] != sep && coding[l]) l++; + l++; + } + + for (i = 0; coding[l+i] != sep; i++) { + if (coding[l+i] == '\0') break; + label[i] = coding[l+i]; + } + label[i] = '\0'; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int number_of_nodes(char *struc) +{ + int l, c, i; + + l = strlen(struc); + for (c = 0, i = 0; i < l; i++) if (struc[i] == ')') c++; + return (c); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void print_keyroots(int *keyroots) +{ + int i; + + printf("---> key roots <---\n\n"); + + printf("entries: %d\n", keyroots[0]); + printf("{"); + for (i = 1; i <= keyroots[0]; i++) printf(" %d", keyroots[i]); + printf(" }\n\n"); +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void print_postorder_list(Postorder_list *pl) +{ + register i; + char label[100]; + + printf("---> postorder list <---\n\n"); + + for (i = 1; i <= pl[0].sons; i++) { + printf(" postorder: %3d\n", i); + *label = '\0'; + encode(pl[i].type, label); + printf(" type: %3d (%s)\n", pl[i].type, label); + printf(" weight: %3d\n", pl[i].weight); + printf(" father: %3d\n", pl[i].father); + printf(" sons: %3d\n", pl[i].sons); + printf("leftmost leaf: %3d\n", pl[i].leftmostleaf); + printf("\n"); + } +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC void print_tree(Tree *t) +{ + print_postorder_list(t->postorder_list); + print_keyroots(t->keyroots); + fflush(stdout); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC void free_tree(Tree *t) +{ + free(t->postorder_list); + free(t->keyroots); + free(t); +} + +/*---------------------------------------------------------------------------*/ + + +PRIVATE void backtracking(void) +{ + int li,lj,i1,j1,i1_1,j1_1,li1_1,lj1_1,f; + int cost, lleaf_i1, lleaf_j1, ss, i,j,k; + struct {int i,j;} sector[MNODES/2]; + + ss=0; + + i=i1=tree1->postorder_list[0].sons; + j=j1=tree2->postorder_list[0].sons; + + start: + li = tree1->postorder_list[i].leftmostleaf; + lj = tree2->postorder_list[j].leftmostleaf; + + + while ((i1>=li)&&(j1>=lj)) { + + lleaf_i1 = tree1->postorder_list[i1].leftmostleaf; + li1_1 = (li > lleaf_i1-1 ? 0 : lleaf_i1-1); + i1_1 = (i1 == li ? 0: i1-1); + lleaf_j1 = tree2->postorder_list[j1].leftmostleaf; + lj1_1 = (lj > lleaf_j1-1 ? 0 : lleaf_j1-1); + j1_1 = (j1 == lj ? 0: j1-1); + + f = fdist[i1][j1]; + + cost = edit_cost(i1, 0); + if (f == fdist[i1_1][j1] + cost) { + alignment[0][i1]=0; + i1=i1_1; + } + else { + if (f == fdist[i1][j1_1] + edit_cost(0, j1)) { + alignment[1][j1]=0; + j1=j1_1; + } + else if (lleaf_i1 == li && lleaf_j1 == lj) { + alignment[0][i1] = j1; + alignment[1][j1] = i1; + i1=i1_1; j1=j1_1; + } else { + sector[ss].i=i1; + sector[ss++].j=j1; + i1=li1_1; + j1=lj1_1; + } + } + } + for (; i1>=li; ) { + alignment[0][i1]=0; + i1 = (i1 == li ? 0: i1-1); + } + for (; j1>=lj; ) { + alignment[1][j1]=0; + j1 = (j1 == lj ? 0: j1-1); + } + while (ss>0) { + i1=sector[--ss].i; + j1=sector[ss].j; + for (k=1; 1; k++) { + i = tree1->keyroots[k]; + if (tree1->postorder_list[i].leftmostleaf == + tree1->postorder_list[i1].leftmostleaf) break; + } + for (k=1; 1; k++) { + j = tree2->keyroots[k]; + if (tree2->postorder_list[j].leftmostleaf == + tree2->postorder_list[j1].leftmostleaf) break; + } + tree_dist(i,j); + goto start; + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void sprint_aligned_trees(void) +{ + int i,j,n1,n2,k,l,p, ni, nj, weights; + char t1[2*MNODES+1], t2[2*MNODES+1], a1[8*MNODES], a2[8*MNODES], ll[20], ll1[20]; + + weights=0; + n1=tree1->postorder_list[0].sons; + n2=tree2->postorder_list[0].sons; + for (i=1; i<=n1; i++) weights |= (tree1->postorder_list[i].weight!=1); + for (i=1; i<=n2; i++) weights |= (tree2->postorder_list[i].weight!=1); + + for (i=n1, l=2*n1-1; i>0; i--) { + if (alignment[0][i]!=0) t1[l--]=']'; + else t1[l--]=')'; + p=i; + while(i==tree1->postorder_list[p].leftmostleaf) { + if (alignment[0][p]!=0) t1[l--]='['; + else t1[l--]='('; + p=tree1->postorder_list[p].father; + } + } + t1[2*n1]='\0'; + for (j=n2, l=2*n2-1; j>0; j--) { + if (alignment[1][j]!=0) t2[l--]=']'; + else t2[l--]=')'; + p=j; + while(j==tree2->postorder_list[p].leftmostleaf) { + if (alignment[1][p]!=0) t2[l--]='['; + else t2[l--]='('; + p=tree2->postorder_list[p].father; + } + } + t2[2*n2]='\0'; + + ni=nj=l=i=j=0; + while (t1[i]||t2[j]) { + while ((t1[i]=='(')||(t1[i]==')')) { + if (t1[i]==')') { + ni++; + encode(tree1->postorder_list[ni].type, ll); + if (weights) + sprintf(ll+strlen(ll), "%d", tree1->postorder_list[ni].weight); + for (k=0; k< strlen(ll); k++) { + a1[l]=ll[k]; + a2[l++]='_'; + } + a1[l]=')'; a2[l++]='_'; + } else { + a1[l] = t1[i]; + a2[l++] ='_'; + } + i++; + } + + while ((t2[j]=='(')||(t2[j]==')')) { + if (t2[j]==')') { + nj++; + encode(tree2->postorder_list[nj].type, ll); + if (weights) + sprintf(ll+strlen(ll), "%d", tree2->postorder_list[nj].weight); + for (k=0; k< strlen(ll); k++) { + a2[l]=ll[k]; + a1[l++]='_'; + } + a2[l]=')'; a1[l++]='_'; + } else { + a2[l] = t2[j]; + a1[l++] ='_'; + } + j++; + } + + if (t2[j]==']') { + ni++; nj++; + encode(tree2->postorder_list[nj].type, ll); + if (weights) + sprintf(ll+strlen(ll), "%d", tree2->postorder_list[nj].weight); + encode(tree1->postorder_list[ni].type, ll1); + if (weights) + sprintf(ll1+strlen(ll1), "%d", tree1->postorder_list[ni].weight); + if (strlen(ll)>strlen(ll1)) + for (k=0; k8*MNODES) nrerror("structure too long in sprint_aligned_trees"); + if (aligned_line[0]!= NULL) free(aligned_line[0]); + if (aligned_line[1]!= NULL) free(aligned_line[1]); + aligned_line[0] = (char *) space((l+1)*sizeof(char)); + aligned_line[1] = (char *) space((l+1)*sizeof(char)); + strcpy(aligned_line[0], a1); + strcpy(aligned_line[1], a2); +} + +/*---------------------------------------------------------------------------*/ diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/treedist.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/treedist.o new file mode 100755 index 0000000000000000000000000000000000000000..098b5dbebddb959bf7fcd4ff0f26616cc15cc67a GIT binary patch literal 46336 zcmeHw3wTu3)%Ka30S1XofQYDoBMg#25)ufI1k?;pV4_ihTnN_~CJ97C5|W7^g>Xrt zj$>i*IxU2&YU?}n^!PB&fzfla2OXFw#KMoxPD;ExkAh}h8brYfk-dZ0>Nk? zcq-67^{GI6=8l5M=>m+nIC zYIm-S_%|d3A_IU_5eV-0M^?j`U|)6=;44q$RCQ!@`m-U$*FGm2h%E5B{NboOZ+Cw1 zm5ft?+X^DyBfjW?KxF8iV@JM;MorT{1$^*@o!;jCks7d&n(=xzoZIuF;g1S}AG-5i z4Mf1J42b6I(R~FG&#^lppU-q|y*TXr#grQF(&pa_SA-$=rU#*|E{jYGM9x6p3!qwo 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b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/utils.c new file mode 100755 index 00000000..4f24e630 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/utils.c @@ -0,0 +1,332 @@ +/* + utils.c + + c Ivo L Hofacker and Walter Fontana + Vienna RNA package +*/ +/* Last changed Time-stamp: <2002-11-07 11:34:11 ivo> */ + +#include +#include +#include +#include +#include +#include "../config.h" +#ifdef WITH_DMALLOC +#include "dmalloc.h" +#endif +/*@unused@*/ +static char rcsid[] = "$Id: utils.c,v 1.15 2005/02/10 09:59:25 ivo Exp $"; + +#define PRIVATE static +#define PUBLIC + +/*@notnull@ @only@*/ +PUBLIC void *space(unsigned int size); +/*@exits@*/ +PUBLIC void nrerror(const char message[]); +PUBLIC double urn(void); +PUBLIC int int_urn(int from, int to); +PUBLIC void filecopy(FILE *from, FILE *to); +/*@observer@*/ +PUBLIC char *time_stamp(void); +PUBLIC char *random_string(int l, const char symbols[]); +PUBLIC int hamming(const char *s1, const char *s2); +PUBLIC char *get_line(FILE *fp); + +PUBLIC unsigned short xsubi[3]; + +/*-------------------------------------------------------------------------*/ + +PUBLIC void *space(unsigned size) { + void *pointer; + + if ( (pointer = (void *) calloc(1, (size_t) size)) == NULL) { +#ifdef EINVAL + if (errno==EINVAL) { + fprintf(stderr,"SPACE: requested size: %d\n", size); + nrerror("SPACE allocation failure -> EINVAL"); + } + if (errno==ENOMEM) +#endif + nrerror("SPACE allocation failure -> no memory"); + } + return pointer; +} + +#ifdef WITH_DMALLOC +#define space(S) calloc(1,(S)) +#endif + +#undef xrealloc +/* dmalloc.h #define's xrealloc */ +void *xrealloc (void *p, unsigned size) { + if (p == 0) + return space(size); + p = (void *) realloc(p, size); + if (p == NULL) { +#ifdef EINVAL + if (errno==EINVAL) { + fprintf(stderr,"xrealloc: requested size: %d\n", size); + nrerror("xrealloc allocation failure -> EINVAL"); + } + if (errno==ENOMEM) +#endif + nrerror("xrealloc allocation failure -> no memory"); + } + return p; +} + +/*------------------------------------------------------------------------*/ + +PUBLIC void nrerror(const char message[]) /* output message upon error */ +{ + fprintf(stderr, "\n%s\n", message); + exit(EXIT_FAILURE); +} + +/*------------------------------------------------------------------------*/ +PUBLIC void init_rand(void) +{ + time_t t; + (void) time(&t); + xsubi[0] = xsubi[1] = xsubi[2] = (unsigned short) t; /* lower 16 bit */ + xsubi[1] += (unsigned short) ((unsigned)t >> 6); + xsubi[2] += (unsigned short) ((unsigned)t >> 12); +#ifndef HAVE_ERAND48 + srand((unsigned int) t); +#endif +} + +/*------------------------------------------------------------------------*/ + +PUBLIC double urn(void) + /* uniform random number generator; urn() is in [0,1] */ + /* uses a linear congruential library routine */ + /* 48 bit arithmetic */ +{ +#ifdef HAVE_ERAND48 + extern double erand48(unsigned short[]); + return erand48(xsubi); +#else + return ((double) rand())/RAND_MAX; +#endif +} + +/*------------------------------------------------------------------------*/ + +PUBLIC int int_urn(int from, int to) +{ + return ( ( (int) (urn()*(to-from+1)) ) + from ); +} + +/*------------------------------------------------------------------------*/ + +PUBLIC void filecopy(FILE *from, FILE *to) +{ + int c; + + while ((c = getc(from)) != EOF) (void)putc(c, to); +} + +/*-----------------------------------------------------------------*/ + +PUBLIC char *time_stamp(void) +{ + time_t cal_time; + + cal_time = time(NULL); + return ( ctime(&cal_time) ); +} + +/*-----------------------------------------------------------------*/ + +PUBLIC char *random_string(int l, const char symbols[]) +{ + char *r; + int i, rn, base; + + base = (int) strlen(symbols); + r = (char *) space(sizeof(char)*(l+1)); + + for (i = 0; i < l; i++) { + rn = (int) (urn()*base); /* [0, base-1] */ + r[i] = symbols[rn]; + } + r[l] = '\0'; + return r; +} + +/*-----------------------------------------------------------------*/ + +PUBLIC int hamming(const char *s1, const char *s2) +{ + int h=0; + + for (; *s1 && *s2; s1++, s2++) + if (*s1 != *s2) h++; + return h; +} +/*-----------------------------------------------------------------*/ + +PUBLIC char *get_line(FILE *fp) /* reads lines of arbitrary length from fp */ +{ + char s[512], *line, *cp; + + line = NULL; + do { + if (fgets(s, 512, fp)==NULL) break; + cp = strchr(s, '\n'); + if (cp != NULL) *cp = '\0'; + if (line==NULL) + line = space(strlen(s)+1); + else + line = (char *) xrealloc(line, strlen(s)+strlen(line)+1); + strcat(line, s); + } while(cp==NULL); + + return line; +} + +/*-----------------------------------------------------------------*/ + +PUBLIC char *pack_structure(const char *struc) { + /* 5:1 compression using base 3 encoding */ + int i,j,l,pi; + unsigned char *packed; + + l = (int) strlen(struc); + packed = (unsigned char *) space(((l+4)/5+1)*sizeof(unsigned char)); + + j=i=pi=0; + while (i=0; k--) { + c = p % 3; + p /= 3; + struc[j+k] = code[c]; + } + j += 5; + } + struc[j--] = '\0'; + while (struc[j] == '(') /* strip trailing ( */ + struc[j--] = '\0'; + + return struc; +} + +/*--------------------------------------------------------------------------*/ + +PUBLIC short *make_pair_table(const char *structure) +{ + /* returns array representation of structure. + table[i] is 0 if unpaired or j if (i.j) pair. */ + short i,j,hx; + short length; + short *stack; + short *table; + + length = (short) strlen(structure); + stack = (short *) space(sizeof(short)*(length+1)); + table = (short *) space(sizeof(short)*(length+2)); + table[0] = length; + + for (hx=0, i=1; i<=length; i++) { + switch (structure[i-1]) { + case '(': + stack[hx++]=i; + break; + case ')': + j = stack[--hx]; + if (hx<0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in make_pair_table"); + } + table[i]=j; + table[j]=i; + break; + default: /* unpaired base, usually '.' */ + table[i]= 0; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in make_pair_table"); + } + free(stack); + return(table); +} + +/*---------------------------------------------------------------------------*/ + +PUBLIC int bp_distance(const char *str1, const char *str2) +{ + /* dist = {number of base pairs in one structure but not in the other} */ + /* same as edit distance with pair_open pair_close as move set */ + int dist; + short i,l; + short *t1, *t2; + + dist = 0; + t1 = make_pair_table(str1); + t2 = make_pair_table(str2); + + l = (t1[0]i) dist++; + if (t2[i]>i) dist++; + } + free(t1); free(t2); + return dist; +} + +#ifndef HAVE_STRDUP +char *strdup(const char *s) { + char *dup; + + dup = space(strlen(s)+1); + strcpy(dup, s); + return(dup); +} +#endif diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/utils.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/utils.o new file mode 100755 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of GNU make to not export all variables. +# Otherwise a system limit (for SysV at least) may be exceeded. +.NOEXPORT: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1 new file mode 100755 index 00000000..8b724b24 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1 @@ -0,0 +1,41 @@ +.\" .ER +.TH "RNALFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNALfold \- calculate locally stable secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNALfold\fP [\-L span] [\-T\ \fItemp\fP] [\-4] [\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] [\-nsp\ \fIpairs\fP] + +.SH "DESCRIPTION" +.I RNALfold +computes locally stable RNA secondary structure with a maximal base pair +span. For a sequence of length n and a base pair span of L the +algorithm uses only O(n+L*L) memory and O(n*L*L) CPU time. Thus it is +practical to "scan" very large genomes for short RNA structures. + +Output consists of a list of secondary structure components of size <= +L, one entry per line. Each output line contains the predicted local +structure its energy in kcal/mol and the starting position of the +local structure. + +.SH "OPTIONS" +.TP +.B \-L span +Set the maximum allowed separation of a base pair to span. I.e. no +pairs (i,j) with j\-i>span will be allowed. +.PP +The \fB\-T\fP, \fB\-d\fP \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in +RNAfold. Most tests were done using "\-d2 \-noLP", other dangling end +settings may still be buggy. + +.SH "REFERENCES" +I.L. Hofacker, B. Priwitzer, and P.F. Stadler +"Prediction of Locally Stable RNA Secondary Structures for Genome\-Wide +Surveys" +Bioinformatics, 20, 186\-190 (2004) +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler. +.br +Send comments to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1.in new file mode 100755 index 00000000..ef9b89a6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNALfold.1.in @@ -0,0 +1,41 @@ +.\" .ER +.TH "RNALFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNALfold \- calculate locally stable secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNALfold\fP [\-L span] [\-T\ \fItemp\fP] [\-4] [\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] [\-nsp\ \fIpairs\fP] + +.SH "DESCRIPTION" +.I RNALfold +computes locally stable RNA secondary structure with a maximal base pair +span. For a sequence of length n and a base pair span of L the +algorithm uses only O(n+L*L) memory and O(n*L*L) CPU time. Thus it is +practical to "scan" very large genomes for short RNA structures. + +Output consists of a list of secondary structure components of size <= +L, one entry per line. Each output line contains the predicted local +structure its energy in kcal/mol and the starting position of the +local structure. + +.SH "OPTIONS" +.TP +.B \-L span +Set the maximum allowed separation of a base pair to span. I.e. no +pairs (i,j) with j\-i>span will be allowed. +.PP +The \fB\-T\fP, \fB\-d\fP \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in +RNAfold. Most tests were done using "\-d2 \-noLP", other dangling end +settings may still be buggy. + +.SH "REFERENCES" +I.L. Hofacker, B. Priwitzer, and P.F. Stadler +"Prediction of Locally Stable RNA Secondary Structures for Genome\-Wide +Surveys" +Bioinformatics, 20, 186\-190 (2004) +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler. +.br +Send comments to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1 new file mode 100755 index 00000000..d320d16f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1 @@ -0,0 +1,97 @@ +.\" .ER +.TH "RNAalifold" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAalifold \- calculate secondary structures for a set of aligned RNAs +.SH "SYNOPSIS" +\fBRNAalifold\fP [\-cv \ \fIweight\fP] [\-nc \ \fIweight\fP] [\-E] +[\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] +[\-d] [\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ +\fIparamfile\fP] [\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [\fI\fP] + +.SH "DESCRIPTION" +.I RNAalifold +reads aligned RNA sequences from stdin or \fIfile.aln\fP and calculates +their minimum free energy (mfe) structure, partition function (pf) and base +pairing probability matrix. Currently, the input alignment has to be in +CLUSTAL format. It returns the mfe structure in bracket notation, its +energy, the free energy of the thermodynamic ensemble and the frequency of +the mfe structure in the ensemble to stdout. It also produces Postscript +files with plots of the resulting secondary structure graph ("alirna.ps") +and a "dot plot" of the base pairing matrix ("alidot.ps"). The file +"alifold.out" will contain a list of likely pairs sorted by credibility, +suitable for viewing with "AliDot.pl". +.SH "OPTIONS" +.TP +.B \-cv \fIfactor\fP +Set the weight of the covariance term in the energy function to +\fIfactor\fP. Default is 1. +.TP +.B \-nc \fIfactor\fP +Set the penalty for non\-compatible sequences in the covariance term of the +energy function to \fIfactor\fP. Default is 1. +.TP +.B \-E +Score pairs with endgaps same as gap-gap pairs. +.TP +.B \-mis +Output "most informative sequence" instead of simple consensus: For each +column of the alignment output the set of nucleotides with frequence greater +than average in IUPAC notation. +.TP +.B \-p +Calculate the partition function and base pairing probability matrix in +addition to the mfe structure. Default is calculation of mfe structure only. +.TP +.B \-noLP +Avoid structures without lonely pairs (helices of length 1). In the mfe +case structures with lonely pairs are strictly forbidden. For partition +function folding this disallows pairs that can \fBonly\fP occur isolated. +Setting this option provides a significant speedup. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options \fUshould\fP work as in RNAfold + +If using \fB\-C\fP constraints will be read from stdin, the alignment +has to given as a filename on the command line. + +.SH "CAVEATS" +Since gaps are not removed for the evaluation of energies, it may be +of advantage to remove any columns with more than, say, 75% gaps from +the alignment before folding with RNAalifold. + +Sequences are not weighted. If possible, do not mix very similar and +dissimilar sequences. Duplicate sequences, for example, can distort the +prediction. +.SH "SEE ALSO" +The ALIDOT package http://www.tbi.univie.ac.at/RNA/ALIDOT/ +.SH "REFERENCES" +The algorithm is a variant of the dynamic programming algorithms of +M. Zuker and P. Stiegler (mfe) and J.S. McCaskill (pf) adapted for sets of +aligned sequences with covariance information. +The energy parameters are taken from: +.br +.PP +D.H. Mathews, J. Sabina, M. Zuker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides Robust +Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.br +If you use this program in your work you might want to cite: +.br +.PP +Ivo L. Hofacker, Martin Fekete, and Peter F. Stadler +"Secondary Structure Prediction for Aligned RNA Sequences" +J.Mol.Biol. 319: 1059\-1066 (2002). +.br +.SH "VERSION" +This man page documents version 1.6 of the Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. + +\" LocalWords: RNAalifold ViennaRNA RNAs fBRNAalifold fP fI fItemp noLP noGU +\" LocalWords: noCloseGU fIparamfile nsp fIpairs fIscale fIfile aln stdin mfe +\" LocalWords: alirna ps alidot alifold AliDot TP cv fIfactor nc fBonly fB br +\" LocalWords: fUshould RNAfold Stiegler McCaskill JMB Fekete CLUSTAL stdout diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1.in new file mode 100755 index 00000000..07d437ee --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAalifold.1.in @@ -0,0 +1,97 @@ +.\" .ER +.TH "RNAalifold" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAalifold \- calculate secondary structures for a set of aligned RNAs +.SH "SYNOPSIS" +\fBRNAalifold\fP [\-cv \ \fIweight\fP] [\-nc \ \fIweight\fP] [\-E] +[\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] +[\-d] [\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ +\fIparamfile\fP] [\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [\fI\fP] + +.SH "DESCRIPTION" +.I RNAalifold +reads aligned RNA sequences from stdin or \fIfile.aln\fP and calculates +their minimum free energy (mfe) structure, partition function (pf) and base +pairing probability matrix. Currently, the input alignment has to be in +CLUSTAL format. It returns the mfe structure in bracket notation, its +energy, the free energy of the thermodynamic ensemble and the frequency of +the mfe structure in the ensemble to stdout. It also produces Postscript +files with plots of the resulting secondary structure graph ("alirna.ps") +and a "dot plot" of the base pairing matrix ("alidot.ps"). The file +"alifold.out" will contain a list of likely pairs sorted by credibility, +suitable for viewing with "AliDot.pl". +.SH "OPTIONS" +.TP +.B \-cv \fIfactor\fP +Set the weight of the covariance term in the energy function to +\fIfactor\fP. Default is 1. +.TP +.B \-nc \fIfactor\fP +Set the penalty for non\-compatible sequences in the covariance term of the +energy function to \fIfactor\fP. Default is 1. +.TP +.B \-E +Score pairs with endgaps same as gap-gap pairs. +.TP +.B \-mis +Output "most informative sequence" instead of simple consensus: For each +column of the alignment output the set of nucleotides with frequence greater +than average in IUPAC notation. +.TP +.B \-p +Calculate the partition function and base pairing probability matrix in +addition to the mfe structure. Default is calculation of mfe structure only. +.TP +.B \-noLP +Avoid structures without lonely pairs (helices of length 1). In the mfe +case structures with lonely pairs are strictly forbidden. For partition +function folding this disallows pairs that can \fBonly\fP occur isolated. +Setting this option provides a significant speedup. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options \fUshould\fP work as in RNAfold + +If using \fB\-C\fP constraints will be read from stdin, the alignment +has to given as a filename on the command line. + +.SH "CAVEATS" +Since gaps are not removed for the evaluation of energies, it may be +of advantage to remove any columns with more than, say, 75% gaps from +the alignment before folding with RNAalifold. + +Sequences are not weighted. If possible, do not mix very similar and +dissimilar sequences. Duplicate sequences, for example, can distort the +prediction. +.SH "SEE ALSO" +The ALIDOT package http://www.tbi.univie.ac.at/RNA/ALIDOT/ +.SH "REFERENCES" +The algorithm is a variant of the dynamic programming algorithms of +M. Zuker and P. Stiegler (mfe) and J.S. McCaskill (pf) adapted for sets of +aligned sequences with covariance information. +The energy parameters are taken from: +.br +.PP +D.H. Mathews, J. Sabina, M. Zuker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides Robust +Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.br +If you use this program in your work you might want to cite: +.br +.PP +Ivo L. Hofacker, Martin Fekete, and Peter F. Stadler +"Secondary Structure Prediction for Aligned RNA Sequences" +J.Mol.Biol. 319: 1059\-1066 (2002). +.br +.SH "VERSION" +This man page documents version @VERSION@ of the Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. + +\" LocalWords: RNAalifold ViennaRNA RNAs fBRNAalifold fP fI fItemp noLP noGU +\" LocalWords: noCloseGU fIparamfile nsp fIpairs fIscale fIfile aln stdin mfe +\" LocalWords: alirna ps alidot alifold AliDot TP cv fIfactor nc fBonly fB br +\" LocalWords: fUshould RNAfold Stiegler McCaskill JMB Fekete CLUSTAL stdout diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1 new file mode 100755 index 00000000..0bd7788f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1 @@ -0,0 +1,86 @@ +.\" .ER +.TH "RNACOFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAcofold \- calculate secondary structures of two RNAs with dimerization +.SH "SYNOPSIS" +\fBRNAcofold\fP [\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] [\-d[0|1|2|3]] +[\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] +[\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [\-a\] [\-c\] [\-f\ \f concentrationfile\fP] + +.SH "DESCRIPTION" +.I RNAcofold +works much like RNAfold, but allows to specify two RNA sequences wich are +then allowed to form a dimer structure. RNA sequences are read from stdin +in the usual format. To compute the hybrid structure of two molecules, the +two sequences must be concatenated using the '&' character as separator. +RNAcofold can compute minimum free energy (mfe) structures, as well as +partition function (pf) and base pairing probability matrix (using the +-p switch). +.br +Since dimer formation is concentration dependent, RNAcofold can be used +to compute equilibrium concentrations for all five monomer and +(homo/hetero)-dimer species, given input concentrations for the monomers. +.br +Output consists of the mfe structure in bracket notation as well as PostScript +structure plots and "dot plot" files containing the pair probabilities, see +the RNAfold man page for details. In the dot plots a cross marks the chain +break between the two concatenated sequences. +.br +The program will continue to read new sequences until a line consisting +of the single character @ or an end of file condition is encountered. +.SH "OPTIONS" +.TP +.B \-a +Compute the partition function and free energies not only of the +hetero-dimer consisting of the two input sequences (the "AB dimer"), +but also of the homo-dimers AA and BB as well as A and B monomers. +The output will contain the free energies for each of these species, +as well as 5 dot plots containing the conditional pair probabilities, +called ABname5.ps, AAname5.ps and so on. For later use, these dot plot +files also contain the free energy of the ensemble as a comment. Using +\fB\-a\fP automatically toggles the +\fB\-p\fP option. +.TP +.B \-c +In addition to everything listed under the \fB\-a\fP option, read in +initial monomer concentrations and compute the expected equilibrium +concentrations of the 5 possible species (AB, AA, BB, A, B). Start +concentrations are read from stdin (unless the -f option is +used) in [mol/l], equilibrium concentrations are given realtive to the +sum of the two inputs. An arbitrary number of initial concentrations +can be specified (one pair of concentrations per line). +.TP +.B \-f\ \fIconcfile\fP +Specify a file with initial concentrations for the to sequences. The table +consits of arbitrary many lines with just two numbers (the concentration of +sequence A and B). Will automatically toggle the \fB\-c\fP (and thus +\fB\-a\fP and \fB\-p\fP) options (see above). +.PP +the \-p, \-p0, \-noGU, \-noCloseGU, \-nsp, \-S, \-e, \-P, \-noLP, \-T, \-4, +\-d and \-C options work as in \fBRNAfold\fP, see there for description. + +.SH "REFERENCES" +The energy parameters are taken from: +.br +D.H. Mathews, J. Sabina, M. Zucker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides +Robust Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.PP +S.H.Bernhart, Ch. Flamm, P.F. Stadler, I.L. Hofacker +Partition Function and Base Pairing Probabilities of RNA Heterodimers +submitted to Algorithms Mol. Biol. +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler, Stephan Bernhart. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1.in new file mode 100755 index 00000000..56836fd6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAcofold.1.in @@ -0,0 +1,86 @@ +.\" .ER +.TH "RNACOFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAcofold \- calculate secondary structures of two RNAs with dimerization +.SH "SYNOPSIS" +\fBRNAcofold\fP [\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] [\-d[0|1|2|3]] +[\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] +[\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [\-a\] [\-c\] [\-f\ \f concentrationfile\fP] + +.SH "DESCRIPTION" +.I RNAcofold +works much like RNAfold, but allows to specify two RNA sequences wich are +then allowed to form a dimer structure. RNA sequences are read from stdin +in the usual format. To compute the hybrid structure of two molecules, the +two sequences must be concatenated using the '&' character as separator. +RNAcofold can compute minimum free energy (mfe) structures, as well as +partition function (pf) and base pairing probability matrix (using the +-p switch). +.br +Since dimer formation is concentration dependent, RNAcofold can be used +to compute equilibrium concentrations for all five monomer and +(homo/hetero)-dimer species, given input concentrations for the monomers. +.br +Output consists of the mfe structure in bracket notation as well as PostScript +structure plots and "dot plot" files containing the pair probabilities, see +the RNAfold man page for details. In the dot plots a cross marks the chain +break between the two concatenated sequences. +.br +The program will continue to read new sequences until a line consisting +of the single character @ or an end of file condition is encountered. +.SH "OPTIONS" +.TP +.B \-a +Compute the partition function and free energies not only of the +hetero-dimer consisting of the two input sequences (the "AB dimer"), +but also of the homo-dimers AA and BB as well as A and B monomers. +The output will contain the free energies for each of these species, +as well as 5 dot plots containing the conditional pair probabilities, +called ABname5.ps, AAname5.ps and so on. For later use, these dot plot +files also contain the free energy of the ensemble as a comment. Using +\fB\-a\fP automatically toggles the +\fB\-p\fP option. +.TP +.B \-c +In addition to everything listed under the \fB\-a\fP option, read in +initial monomer concentrations and compute the expected equilibrium +concentrations of the 5 possible species (AB, AA, BB, A, B). Start +concentrations are read from stdin (unless the -f option is +used) in [mol/l], equilibrium concentrations are given realtive to the +sum of the two inputs. An arbitrary number of initial concentrations +can be specified (one pair of concentrations per line). +.TP +.B \-f\ \fIconcfile\fP +Specify a file with initial concentrations for the to sequences. The table +consits of arbitrary many lines with just two numbers (the concentration of +sequence A and B). Will automatically toggle the \fB\-c\fP (and thus +\fB\-a\fP and \fB\-p\fP) options (see above). +.PP +the \-p, \-p0, \-noGU, \-noCloseGU, \-nsp, \-S, \-e, \-P, \-noLP, \-T, \-4, +\-d and \-C options work as in \fBRNAfold\fP, see there for description. + +.SH "REFERENCES" +The energy parameters are taken from: +.br +D.H. Mathews, J. Sabina, M. Zucker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides +Robust Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.PP +S.H.Bernhart, Ch. Flamm, P.F. Stadler, I.L. Hofacker +Partition Function and Base Pairing Probabilities of RNA Heterodimers +submitted to Algorithms Mol. Biol. +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler, Stephan Bernhart. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1 new file mode 100755 index 00000000..346882c8 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1 @@ -0,0 +1,83 @@ +.\" .ER +.TH "RNADISTANCE" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAdistance \- calculate distances between RNA secondary structures +.SH "SYNOPSIS" +\fBRNAdistance [\-D[fhwcFHWCP] [\-X[p|m|f|c]] [\-S] [\-B [\fI\fP]] +.SH "DESCRIPTION" +.I RNAdistance +reads RNA secondary structures from stdin and calculates one or more +measures for their dissimilarity, based on tree or string editing +(alignment). In addition it calculates a "base pair distance" given by the +number of base pairs present in one structure, but not the other. For +structures of different length base pair distance is not recommended. + +RNAdistance accepts structures in bracket format, where matching brackets +symbolize base pairs and unpaired bases are represented by a dot ".", +or coarse grained representations where hairpins, interior loops, +bulges, multiloops, stacks and external bases are represented by +(H), (I), (B), (M), (S), and (E), respectively. These can be optionally +weighted. Full structures can be represented in the same fashion using +the identifiers (U) and (P) for unpaired and paired bases, respectively. +We call this the HIT representation (you don't want to know what this means). +For example the following structure consists of 2 hairpins joined by +a multiloop: +.br + + .((..(((...)))..((..)))). full structure (usual format); + (U)((U2)((U3)P3)(U2)((U2)P2)P2) HIT structure; + ((H)(H)M) or + ((((H)S)((H)S)M)S) coarse grained structure; + (((((H3)S3)((H2)S2)M4)S2)E2) weighted coarse grained. +.br + +The program will continue to read new structures until a line consisting +of the single character @ or an end of file condition is encountered. Input +lines neither containing a valid structure nor starting with > are ignored. + +.SH "OPTIONS" +.IP \-D[fhwcFHWCP] +use the full, HIT, weighted coarse, or coarse representation to +calculate the distance. Capital letters indicate string alignment +otherwise tree editing is used. Any combination of distances can be +specified. \fB\-DP\fP selects the base pair distance. The default if "f". +.IP \-Xp +compare the structures pairwise (p), that is first with 2nd, third +with 4th etc. This is the default. +.IP \-Xm +calculate the distance matrix between all structures. The output is +formatted as a lower triangle matrix. +.IP \-Xf +compare each structure to the first one. +.IP \-Xc +compare continuously, that is i\-th with (i+1)th structure. +.IP \-S +Use the Bruce Shapiro's cost matrix for comparing coarse structures. +.IP \-B\ [file] +Print an "alignment" with gaps of the structures, to show matching +substructures. The aligned structures are written to \fIfile\fP, if +specified. Otherwise output is written to stdout, unless the \-Xm +option is set in which case "backtrack.file" is used. +.SH "REFERENCES" +Shapiro B A, (1988) An algorithm for comparing multiple RNA secondary +structures, CABIOS 4, 381\-393 +.br +Shapiro B A, Zhang K (1990) Comparing multiple RNA secondary +structures using tree comparison, CABIOS 6, 309\-318 +.br +Fontana W, Konings D A M, Stadler P F, Schuster P, (1993) +Statistics of RNA secondary structures, Biopolymers 33, 1389\-1404 +.br +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125, 167\-188 +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package +.SH "AUTHORS" +Walter Fontana, Ivo L Hofacker, Peter F Stadler. +.SH "BUGS" +We hoped you wouldn't find them. +Comments should be sent to rna@tbi.univie.ac.at +.br + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1.in new file mode 100755 index 00000000..395760f6 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAdistance.1.in @@ -0,0 +1,83 @@ +.\" .ER +.TH "RNADISTANCE" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAdistance \- calculate distances between RNA secondary structures +.SH "SYNOPSIS" +\fBRNAdistance [\-D[fhwcFHWCP] [\-X[p|m|f|c]] [\-S] [\-B [\fI\fP]] +.SH "DESCRIPTION" +.I RNAdistance +reads RNA secondary structures from stdin and calculates one or more +measures for their dissimilarity, based on tree or string editing +(alignment). In addition it calculates a "base pair distance" given by the +number of base pairs present in one structure, but not the other. For +structures of different length base pair distance is not recommended. + +RNAdistance accepts structures in bracket format, where matching brackets +symbolize base pairs and unpaired bases are represented by a dot ".", +or coarse grained representations where hairpins, interior loops, +bulges, multiloops, stacks and external bases are represented by +(H), (I), (B), (M), (S), and (E), respectively. These can be optionally +weighted. Full structures can be represented in the same fashion using +the identifiers (U) and (P) for unpaired and paired bases, respectively. +We call this the HIT representation (you don't want to know what this means). +For example the following structure consists of 2 hairpins joined by +a multiloop: +.br + + .((..(((...)))..((..)))). full structure (usual format); + (U)((U2)((U3)P3)(U2)((U2)P2)P2) HIT structure; + ((H)(H)M) or + ((((H)S)((H)S)M)S) coarse grained structure; + (((((H3)S3)((H2)S2)M4)S2)E2) weighted coarse grained. +.br + +The program will continue to read new structures until a line consisting +of the single character @ or an end of file condition is encountered. Input +lines neither containing a valid structure nor starting with > are ignored. + +.SH "OPTIONS" +.IP \-D[fhwcFHWCP] +use the full, HIT, weighted coarse, or coarse representation to +calculate the distance. Capital letters indicate string alignment +otherwise tree editing is used. Any combination of distances can be +specified. \fB\-DP\fP selects the base pair distance. The default if "f". +.IP \-Xp +compare the structures pairwise (p), that is first with 2nd, third +with 4th etc. This is the default. +.IP \-Xm +calculate the distance matrix between all structures. The output is +formatted as a lower triangle matrix. +.IP \-Xf +compare each structure to the first one. +.IP \-Xc +compare continuously, that is i\-th with (i+1)th structure. +.IP \-S +Use the Bruce Shapiro's cost matrix for comparing coarse structures. +.IP \-B\ [file] +Print an "alignment" with gaps of the structures, to show matching +substructures. The aligned structures are written to \fIfile\fP, if +specified. Otherwise output is written to stdout, unless the \-Xm +option is set in which case "backtrack.file" is used. +.SH "REFERENCES" +Shapiro B A, (1988) An algorithm for comparing multiple RNA secondary +structures, CABIOS 4, 381\-393 +.br +Shapiro B A, Zhang K (1990) Comparing multiple RNA secondary +structures using tree comparison, CABIOS 6, 309\-318 +.br +Fontana W, Konings D A M, Stadler P F, Schuster P, (1993) +Statistics of RNA secondary structures, Biopolymers 33, 1389\-1404 +.br +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125, 167\-188 +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package +.SH "AUTHORS" +Walter Fontana, Ivo L Hofacker, Peter F Stadler. +.SH "BUGS" +We hoped you wouldn't find them. +Comments should be sent to rna@tbi.univie.ac.at +.br + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1 new file mode 100755 index 00000000..d6ecf477 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1 @@ -0,0 +1,35 @@ +.TH "RNAduplex" "l" "0.0.1" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +.LP +RNAduplex \- Compute the structure upon hybridization of two RNA strands +.SH "SYNTAX" +.LP +RNAduplex [\fI\-e range\fP] [\fIstandard_options\fP] [<\fIfilename\fP>] + +.SH "DESCRIPTION" +.LP +\fIRNAduplex\fR reads two RNA sequences from stdin or \fI\fR and computes optimal and suboptimal secondary structures for their hybridization. The calculation is simplified by allowing only inter\-molecular base pairs, for the general case use \fBRNAcofold\fR. +.LP +The computed optimal and suboptimal structure are written to stdout, one structure per line. +Each line consist of: The structure in dot bracket format with a "&" separating the two strands. The range of the structure in the two sequences in the format "from,to : from,to"; the energy of duplex structure in kcal/mol. +.br +The format is especially useful for computing the hybrid structure between a small probe sequence and a long target sequence. +.SH "OPTIONS" +.LP +.TP +\fB\-e\fR \fIrange\fR +Compute suboptimal structures with energy with \fIrange\fR kcal/mol of the optimum. +Default is calculation of mfe structure only. +.PP +For the standard options, such as +\fB\-T\fR, \fB\-4\fR, \fB\-noGU\fR, \-\fBnoCloseGU\fR, +\fB\-P\fR see the \fBRNAfold\fR man page. + +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +.LP +Ivo Hofacker +.SH "SEE ALSO" +.LP +RNAcofold(l) RNAfold(l) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1.in new file mode 100755 index 00000000..866c9b55 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAduplex.1.in @@ -0,0 +1,35 @@ +.TH "RNAduplex" "l" "0.0.1" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +.LP +RNAduplex \- Compute the structure upon hybridization of two RNA strands +.SH "SYNTAX" +.LP +RNAduplex [\fI\-e range\fP] [\fIstandard_options\fP] [<\fIfilename\fP>] + +.SH "DESCRIPTION" +.LP +\fIRNAduplex\fR reads two RNA sequences from stdin or \fI\fR and computes optimal and suboptimal secondary structures for their hybridization. The calculation is simplified by allowing only inter\-molecular base pairs, for the general case use \fBRNAcofold\fR. +.LP +The computed optimal and suboptimal structure are written to stdout, one structure per line. +Each line consist of: The structure in dot bracket format with a "&" separating the two strands. The range of the structure in the two sequences in the format "from,to : from,to"; the energy of duplex structure in kcal/mol. +.br +The format is especially useful for computing the hybrid structure between a small probe sequence and a long target sequence. +.SH "OPTIONS" +.LP +.TP +\fB\-e\fR \fIrange\fR +Compute suboptimal structures with energy with \fIrange\fR kcal/mol of the optimum. +Default is calculation of mfe structure only. +.PP +For the standard options, such as +\fB\-T\fR, \fB\-4\fR, \fB\-noGU\fR, \-\fBnoCloseGU\fR, +\fB\-P\fR see the \fBRNAfold\fR man page. + +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +.LP +Ivo Hofacker +.SH "SEE ALSO" +.LP +RNAcofold(l) RNAfold(l) diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1 new file mode 100755 index 00000000..db89238a --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1 @@ -0,0 +1,50 @@ +.\" .ER +.TH "RNAEVAL" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAEVAL \- calculate energy of RNA sequences on given secondary structure +.SH "SYNOPSIS" +\fBRNAeval [\-T \fItemp\fP] [\-4] [\-d[0|1|2|3]] [\-logML] [\-e \fI1|2\fP] [\-P \fIparamfile\fP] +.SH "DESCRIPTION" +.I RNAeval +evaluates the free energy of an RNA molecule in fixed secondary +structure. Sequences and structures are read alternately from stdin. +The energy in Kcal/Mol is written to stdout. +.br +The program will continue to read new sequences and structures until a +line consisting of the single character "@" or an end of file condition +is encountered. +.br +If the input sequence or structure contains the separator character "&" the +program calculates the energy of the co\-folding of two RNA strands, where +the "&" marks the boundary between the two strands. +.SH "OPTIONS" +.IP \fB\-d\fB +Do not give stabilizing energies to unpaired bases adjacent to helices in +multiloops and free ends ("dangling ends"). Same as \-d0, opposite of \-d1 +(the default). +.IP \fB\-d2\fB +Treat dangling ends as in the partition function algorithm, i.e. bases +adjacent to helices in multiloops and free ends give a stabilizing energy +contribution, regardless whether they're paired or unpaired. +.IP \fB\-d3\fB +Allow coaxial stacking of adjacent helices in multi\-loops. +.IP \fB\-logML\fB +Let multiloop energies depend logarithmically on the size, instead of the +usual linear energy function. +.PP +The \fB\-T\fP, \fB\-4\fP, \fB\-e\fP, \fB\-P\fP, options work as in RNAfold. +.SH "REFERENCES" +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package +.SH "AUTHOR" +Ivo L Hofacker and Peter F Stadler. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1.in new file mode 100755 index 00000000..45672706 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAeval.1.in @@ -0,0 +1,50 @@ +.\" .ER +.TH "RNAEVAL" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAEVAL \- calculate energy of RNA sequences on given secondary structure +.SH "SYNOPSIS" +\fBRNAeval [\-T \fItemp\fP] [\-4] [\-d[0|1|2|3]] [\-logML] [\-e \fI1|2\fP] [\-P \fIparamfile\fP] +.SH "DESCRIPTION" +.I RNAeval +evaluates the free energy of an RNA molecule in fixed secondary +structure. Sequences and structures are read alternately from stdin. +The energy in Kcal/Mol is written to stdout. +.br +The program will continue to read new sequences and structures until a +line consisting of the single character "@" or an end of file condition +is encountered. +.br +If the input sequence or structure contains the separator character "&" the +program calculates the energy of the co\-folding of two RNA strands, where +the "&" marks the boundary between the two strands. +.SH "OPTIONS" +.IP \fB\-d\fB +Do not give stabilizing energies to unpaired bases adjacent to helices in +multiloops and free ends ("dangling ends"). Same as \-d0, opposite of \-d1 +(the default). +.IP \fB\-d2\fB +Treat dangling ends as in the partition function algorithm, i.e. bases +adjacent to helices in multiloops and free ends give a stabilizing energy +contribution, regardless whether they're paired or unpaired. +.IP \fB\-d3\fB +Allow coaxial stacking of adjacent helices in multi\-loops. +.IP \fB\-logML\fB +Let multiloop energies depend logarithmically on the size, instead of the +usual linear energy function. +.PP +The \fB\-T\fP, \fB\-4\fP, \fB\-e\fP, \fB\-P\fP, options work as in RNAfold. +.SH "REFERENCES" +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package +.SH "AUTHOR" +Ivo L Hofacker and Peter F Stadler. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1 new file mode 100755 index 00000000..48f90773 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1 @@ -0,0 +1,179 @@ +.\" .ER +.TH "RNAFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAfold \- calculate secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNAfold\fP [\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] [\-d[0|1|2|3]] +[\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] +[\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [-circ] + +.SH "DESCRIPTION" +.I RNAfold +reads RNA sequences from stdin, calculates their minimum free energy +(mfe) structure and prints to stdout the mfe structure in bracket +notation and its free energy. If the \-p option was given it also +computes the partition function (pf) and base pairing probability +matrix, and prints the free energy of the thermodynamic ensemble, the +frequency of the mfe structure in the ensemble, and the ensemble +diversity to stdout. + +It also produces PostScript files with plots of the resulting +secondary structure graph and a "dot plot" of the base pairing matrix. +The dot plot shows a matrix of squares with area proportional to the +pairing probability in the upper half, and one square for each pair in +the minimum free energy structure in the lower half. For each pair +i\-j with probability p>10E\-6 there is a line of the form +.br +i j sqrt(p) ubox +.br +in the PostScript file, so that the pair probabilities can be easily +extracted. +If the sequence is preceded by a line of the form +.br +> name +.br +then the PostScript files "name_ss.ps" and "name_dp.ps" are produced for +the structure and dot plot, respectively. Otherwise the filenames +default to rna.ps and dot.ps. Existing files of the same name will be +overwritten. +.br +The program will continue to read new sequences until a line consisting +of the single character @ or an end of file condition is encountered. +.SH "OPTIONS" +.TP +.B \-p +Calculate the partition function and base pairing probability matrix in +addition to the mfe structure. Default is calculation of mfe structure +only. Prints a coarse representation of the pair probabilities in +form of a pseudo bracket notation, the ensemble free energy, the +frequency of the mfe structure, and the structural diversity. +See the description of pf_fold() and mean_bp_dist() in the RNAlib +documentation for details. +.br +Note that unless you also specify \-d2 or \-d0, the partition +function and mfe calculations will use a slightly different energy +model. See the discussion of dangling end options below. +.TP +.B \-p0 +Calculate the partition function but not the pair probabilities, +saving about 50% in runtime. Prints the ensemble free energy \-kT ln(Z). +.TP +.B \-C +Calculate structures subject to constraints. +The program reads first the sequence, then a string containing constraints +on the structure encoded with the symbols: +. (no constraint for this base) +| (the corresponding base has to be paired +x (the base is unpaired) +< (base i is paired with a base j>i) +> (base i is paired with a base j\fP +Read energy parameters from \fIparamfile\fP, instead of using the default +parameter set. A sample parameter file should accompany your distribution. +See the RNAlib documentation for details on the file format. +.TP +.B \-nsp \fIpairs\fP +Allow other pairs in addition to the usual AU,GC,and GU pairs. \fIpairs\fP +is a comma separated list of additionally allowed pairs. If a the first +character is a "\-" then AB will imply that AB and BA are allowed pairs. +e.g. RNAfold \-nsp \-GA will allow GA and AG pairs. Nonstandard pairs are +given 0 stacking energy. +.TP +.B \-S\ \fIscale\fP +In the calculation of the pf use \fIscale\fP*mfe as an estimate for the +ensemble free energy (used to avoid overflows). The default is 1.07, +useful values are 1.0 to 1.2. Occasionally needed for long sequences. +You can also recompile the program to use double precision (see the README +file). +.TP +.B \-circ +Assume a circular (instead of linear) RNA molecule. Currently works only +for mfe folding. + +.SH "REFERENCES" +The calculation of mfe structures is based on dynamic +programming algorithm originally developed by M. Zuker and P. Stiegler. +The partition function algorithm is based on work by J.S. McCaskill. +The energy parameters are taken from: +.br +D.H. Mathews, J. Sabina, M. Zuker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides +Robust Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.br +A. Walter, D Turner, J Kim, M Lyttle, P M\[:u]ller, D Mathews, M Zuker +"Coaxial stacking of helices enhances binding of oligoribonucleotides.." +PNAS, 91, pp 9218\-9222, 1994 +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.br +M. Zuker, P. Stiegler (1981) Optimal computer folding of large RNA +sequences using thermodynamic and auxiliary information, Nucl Acid Res +9: 133\-148 +.br +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Walter Fontana, Sebastian Bonhoeffer, Peter F Stadler. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1.in new file mode 100755 index 00000000..83acce15 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAfold.1.in @@ -0,0 +1,179 @@ +.\" .ER +.TH "RNAFOLD" "l" "1.5" "Ivo Hofacker" "ViennaRNA" +.SH "NAME" +RNAfold \- calculate secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNAfold\fP [\-p[\fI0\fP]] [\-C] [\-T\ \fItemp\fP] [\-4] [\-d[0|1|2|3]] +[\-noLP] [\-noGU] [\-noCloseGU] [\-e\ \fI1|2\fP] [\-P\ \fIparamfile\fP] +[\-nsp\ \fIpairs\fP] [\-S\ \fIscale\fP] [-circ] + +.SH "DESCRIPTION" +.I RNAfold +reads RNA sequences from stdin, calculates their minimum free energy +(mfe) structure and prints to stdout the mfe structure in bracket +notation and its free energy. If the \-p option was given it also +computes the partition function (pf) and base pairing probability +matrix, and prints the free energy of the thermodynamic ensemble, the +frequency of the mfe structure in the ensemble, and the ensemble +diversity to stdout. + +It also produces PostScript files with plots of the resulting +secondary structure graph and a "dot plot" of the base pairing matrix. +The dot plot shows a matrix of squares with area proportional to the +pairing probability in the upper half, and one square for each pair in +the minimum free energy structure in the lower half. For each pair +i\-j with probability p>10E\-6 there is a line of the form +.br +i j sqrt(p) ubox +.br +in the PostScript file, so that the pair probabilities can be easily +extracted. +If the sequence is preceded by a line of the form +.br +> name +.br +then the PostScript files "name_ss.ps" and "name_dp.ps" are produced for +the structure and dot plot, respectively. Otherwise the filenames +default to rna.ps and dot.ps. Existing files of the same name will be +overwritten. +.br +The program will continue to read new sequences until a line consisting +of the single character @ or an end of file condition is encountered. +.SH "OPTIONS" +.TP +.B \-p +Calculate the partition function and base pairing probability matrix in +addition to the mfe structure. Default is calculation of mfe structure +only. Prints a coarse representation of the pair probabilities in +form of a pseudo bracket notation, the ensemble free energy, the +frequency of the mfe structure, and the structural diversity. +See the description of pf_fold() and mean_bp_dist() in the RNAlib +documentation for details. +.br +Note that unless you also specify \-d2 or \-d0, the partition +function and mfe calculations will use a slightly different energy +model. See the discussion of dangling end options below. +.TP +.B \-p0 +Calculate the partition function but not the pair probabilities, +saving about 50% in runtime. Prints the ensemble free energy \-kT ln(Z). +.TP +.B \-C +Calculate structures subject to constraints. +The program reads first the sequence, then a string containing constraints +on the structure encoded with the symbols: +. (no constraint for this base) +| (the corresponding base has to be paired +x (the base is unpaired) +< (base i is paired with a base j>i) +> (base i is paired with a base j\fP +Read energy parameters from \fIparamfile\fP, instead of using the default +parameter set. A sample parameter file should accompany your distribution. +See the RNAlib documentation for details on the file format. +.TP +.B \-nsp \fIpairs\fP +Allow other pairs in addition to the usual AU,GC,and GU pairs. \fIpairs\fP +is a comma separated list of additionally allowed pairs. If a the first +character is a "\-" then AB will imply that AB and BA are allowed pairs. +e.g. RNAfold \-nsp \-GA will allow GA and AG pairs. Nonstandard pairs are +given 0 stacking energy. +.TP +.B \-S\ \fIscale\fP +In the calculation of the pf use \fIscale\fP*mfe as an estimate for the +ensemble free energy (used to avoid overflows). The default is 1.07, +useful values are 1.0 to 1.2. Occasionally needed for long sequences. +You can also recompile the program to use double precision (see the README +file). +.TP +.B \-circ +Assume a circular (instead of linear) RNA molecule. Currently works only +for mfe folding. + +.SH "REFERENCES" +The calculation of mfe structures is based on dynamic +programming algorithm originally developed by M. Zuker and P. Stiegler. +The partition function algorithm is based on work by J.S. McCaskill. +The energy parameters are taken from: +.br +D.H. Mathews, J. Sabina, M. Zuker and H. Turner +"Expanded Sequence Dependence of Thermodynamic Parameters Provides +Robust Prediction of RNA Secondary Structure" +JMB, 288, pp 911\-940, 1999 +.br +A. Walter, D Turner, J Kim, M Lyttle, P M\[:u]ller, D Mathews, M Zuker +"Coaxial stacking of helices enhances binding of oligoribonucleotides.." +PNAS, 91, pp 9218\-9222, 1994 +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.br +M. Zuker, P. Stiegler (1981) Optimal computer folding of large RNA +sequences using thermodynamic and auxiliary information, Nucl Acid Res +9: 133\-148 +.br +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Walter Fontana, Sebastian Bonhoeffer, Peter F Stadler. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1 new file mode 100755 index 00000000..d76a57c4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1 @@ -0,0 +1,60 @@ +.\" .ER +.TH "RNAHEAT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAheat \- calculate specific heat of RNAs +.SH "SYNOPSIS" +\fBRNAheat [\-Tmin \fIt1\fP] [\-Tmax \fIt2\fP] [\-h \fIstepsize\fP] [\-m +\fIipoints\fP] [\-d] [\-4] [\-noGU] [\-noCloseGU] [\-nsp pairs] [\-P paramfile] [\-e \fI1|2\fP] +.SH "DESCRIPTION" +.I RNAheat +reads RNA sequences from stdin and calculates their specific heat +in the temperature range \fIt1\fP to \fIt2\fP, from the partition +function by numeric differentiation. The result is written to stdout +as a list of pairs of temperature in C and specific heat in Kcal/(Mol*K). +.br +The program will continue to read new sequences until a line consisting +of the single character "@" or an end of file condition is encountered. +.SH "OPTIONS" +.IP \fB\-Tmin\ \fIt1\fP +Lowest temperature, default is 0C. +.IP \fB\-Tmax\ \fIt2\fP +Highest temperature, default is 100C. +.IP \fB\-h\ \fIstepsize\fP +Calculate partition function every \fIstepsize\fP degrees C. Default +is 1C. +.IP \fB\-m\ \fIipoints\fP +The program fits a parabola to 2*ipoints+1 data points to calculate +2nd derivatives. Increasing this parameter produces a smoother curve. +Default is 2. +.PP +The \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, \fB\-e\fP, +\fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. +.SH "EXAMPLES" +.nf + RNAheat \-Tmin \-30 \-Tmax 120 \-h 0.1 \-m 4 < tRNA.seq | xmgrace \-pipe +.nf +produces plots of the specific heat of the sequences in tRNA.seq. +.SH "REFERENCES" +The partition function algorithm is based on work by J.S. McCaskill. +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.PP +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler. +.SH "SEE ALSO" +.BR RNAfold (l), +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1.in new file mode 100755 index 00000000..d2893d95 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAheat.1.in @@ -0,0 +1,60 @@ +.\" .ER +.TH "RNAHEAT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAheat \- calculate specific heat of RNAs +.SH "SYNOPSIS" +\fBRNAheat [\-Tmin \fIt1\fP] [\-Tmax \fIt2\fP] [\-h \fIstepsize\fP] [\-m +\fIipoints\fP] [\-d] [\-4] [\-noGU] [\-noCloseGU] [\-nsp pairs] [\-P paramfile] [\-e \fI1|2\fP] +.SH "DESCRIPTION" +.I RNAheat +reads RNA sequences from stdin and calculates their specific heat +in the temperature range \fIt1\fP to \fIt2\fP, from the partition +function by numeric differentiation. The result is written to stdout +as a list of pairs of temperature in C and specific heat in Kcal/(Mol*K). +.br +The program will continue to read new sequences until a line consisting +of the single character "@" or an end of file condition is encountered. +.SH "OPTIONS" +.IP \fB\-Tmin\ \fIt1\fP +Lowest temperature, default is 0C. +.IP \fB\-Tmax\ \fIt2\fP +Highest temperature, default is 100C. +.IP \fB\-h\ \fIstepsize\fP +Calculate partition function every \fIstepsize\fP degrees C. Default +is 1C. +.IP \fB\-m\ \fIipoints\fP +The program fits a parabola to 2*ipoints+1 data points to calculate +2nd derivatives. Increasing this parameter produces a smoother curve. +Default is 2. +.PP +The \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, \fB\-e\fP, +\fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. +.SH "EXAMPLES" +.nf + RNAheat \-Tmin \-30 \-Tmax 120 \-h 0.1 \-m 4 < tRNA.seq | xmgrace \-pipe +.nf +produces plots of the specific heat of the sequences in tRNA.seq. +.SH "REFERENCES" +The partition function algorithm is based on work by J.S. McCaskill. +.PP +If you use this program in your work you might want to cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.PP +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +Ivo L Hofacker, Peter F Stadler. +.SH "SEE ALSO" +.BR RNAfold (l), +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1 new file mode 100755 index 00000000..b7dc49e3 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1 @@ -0,0 +1,107 @@ +.\" .ER +.TH "RNAINVERSE" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAINVERSE \- find RNA sequences with given secondary structure +.SH "SYNOPSIS" +.B RNAinverse [\-F[mp]] [\-R \fIrepeats\fB]] [\-v] [\-a \fIalphabet\fB] +.B [\-f \fIfinal\fB] [\-T \fItemp\fB] [\-d[0|1|2|3] [\-4] [\-noGU] [\-noCloseGU] +.B [\-P \fIparamfile\fB] [\-e \fI1|2\fP] [\-nsp \fIpairs\fP] +.SH "DESCRIPTION" +.I RNAinverse +searches for sequences folding into a predefined structure, thereby +inverting the folding algorithm. Target structures (in bracket notation) +and starting sequences for the search are read alternately from stdin. +Characters in the start sequence other than "AUGC" (or the alphabet +specified with \fB\-a\fP) will be treated as wild cards and replaced by a +random character. Any lower case characters in the start sequence will be +kept fixed during the search. If necessary, the sequence will be elongated +to the length of the structure. Thus a string of "N"s as well as a blank +line specify a random start sequence. +.br +For each search the best sequence found and its Hamming distance +to the start sequence are printed to stdout. If the the search was +unsuccessful, a structure distance to the target is appended. +The \fB\-Fp\fP and \fB\-R\fP options can modify the output format, see below. +.br +The program will continue to read new structures and sequences until a +line consisting of the single character "@" or an end of file condition +is encountered. +.SH "OPTIONS" +.TP +.B \-F[mp] +Use minimum energy (\fB\-Fm\fP), partition function folding (\fB\-Fp\fP) +or both (\fB\-Fmp\fP). +In partition function mode, the probability of the target structure +exp\fI(\-E(S)/kT)/Q\fP is maximized. This probability is written in brackets +after the found sequence and Hamming distance. In most cases you'll want to +use the \fB\-f\fP option in conjunction with \fB\-Fp\fP, see below. The +default is \fB\-Fm\fP. +.TP +.B \-f \fIfinal\fP +In combination with \fB\-Fp\fP stop search when sequence is found with +\fIE(s)\-F\fP is smaller than \fIfinal\fP, where \fIF=\-kT*ln(Q)\fP. +.TP +.B \-R \fIrepeats\fP +Search repeatedly for the same structure. If \fIrepeats\fP is negative +search until \fI\-repeats\fP exact solutions are found, no output is done +for unsuccessful searches. Be aware, that the program will not terminate if +the target structure can not be found. +.TP +.B \-v +in conjunction with \fB\-R\fP and a negative \fIrepeats\fP, print the +last subsequence and substructure for each unsuccessful search. +.TP +.B \-a \fIalphabet\fP +Find sequences using only bases from \fIalphabet\fP. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold +.SH "EXAMPLE" +To search 5 times for sequences forming a simple hairpin structure +interrupted by one GA mismatch call +.br +.ft C +RNAinverse \-R 5 +.ft +.br +and enter the lines +.br +.ft C +(((.(((....))).))) +.br +NNNgNNNNNNNNNNaNNN +.ft + +.SH "REFERENCES" +The calculation of minimum free energy structures is based on dynamic +programming algorithm originally developed by M. Zuker and P. Stiegler. +The partition function algorithm is based on work by J.S. McCaskill. +.br +If this Program proves useful for your work please cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.br +Other useful references are: +.br +M. Zuker, P. Stiegler (1981) Optimal computer folding of large RNA +sequences using thermodynamic and auxiliary information, Nucl Acid Res +9: 133\-148 +.br +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D.H. Turner N. Sugimoto and S.M. Freier (1988) RNA structure +prediction, Ann Rev Biophys Biophys Chem 17: 167\-192 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHOR" +Ivo L Hofacker. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1.in new file mode 100755 index 00000000..c85c5faa --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAinverse.1.in @@ -0,0 +1,107 @@ +.\" .ER +.TH "RNAINVERSE" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAINVERSE \- find RNA sequences with given secondary structure +.SH "SYNOPSIS" +.B RNAinverse [\-F[mp]] [\-R \fIrepeats\fB]] [\-v] [\-a \fIalphabet\fB] +.B [\-f \fIfinal\fB] [\-T \fItemp\fB] [\-d[0|1|2|3] [\-4] [\-noGU] [\-noCloseGU] +.B [\-P \fIparamfile\fB] [\-e \fI1|2\fP] [\-nsp \fIpairs\fP] +.SH "DESCRIPTION" +.I RNAinverse +searches for sequences folding into a predefined structure, thereby +inverting the folding algorithm. Target structures (in bracket notation) +and starting sequences for the search are read alternately from stdin. +Characters in the start sequence other than "AUGC" (or the alphabet +specified with \fB\-a\fP) will be treated as wild cards and replaced by a +random character. Any lower case characters in the start sequence will be +kept fixed during the search. If necessary, the sequence will be elongated +to the length of the structure. Thus a string of "N"s as well as a blank +line specify a random start sequence. +.br +For each search the best sequence found and its Hamming distance +to the start sequence are printed to stdout. If the the search was +unsuccessful, a structure distance to the target is appended. +The \fB\-Fp\fP and \fB\-R\fP options can modify the output format, see below. +.br +The program will continue to read new structures and sequences until a +line consisting of the single character "@" or an end of file condition +is encountered. +.SH "OPTIONS" +.TP +.B \-F[mp] +Use minimum energy (\fB\-Fm\fP), partition function folding (\fB\-Fp\fP) +or both (\fB\-Fmp\fP). +In partition function mode, the probability of the target structure +exp\fI(\-E(S)/kT)/Q\fP is maximized. This probability is written in brackets +after the found sequence and Hamming distance. In most cases you'll want to +use the \fB\-f\fP option in conjunction with \fB\-Fp\fP, see below. The +default is \fB\-Fm\fP. +.TP +.B \-f \fIfinal\fP +In combination with \fB\-Fp\fP stop search when sequence is found with +\fIE(s)\-F\fP is smaller than \fIfinal\fP, where \fIF=\-kT*ln(Q)\fP. +.TP +.B \-R \fIrepeats\fP +Search repeatedly for the same structure. If \fIrepeats\fP is negative +search until \fI\-repeats\fP exact solutions are found, no output is done +for unsuccessful searches. Be aware, that the program will not terminate if +the target structure can not be found. +.TP +.B \-v +in conjunction with \fB\-R\fP and a negative \fIrepeats\fP, print the +last subsequence and substructure for each unsuccessful search. +.TP +.B \-a \fIalphabet\fP +Find sequences using only bases from \fIalphabet\fP. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold +.SH "EXAMPLE" +To search 5 times for sequences forming a simple hairpin structure +interrupted by one GA mismatch call +.br +.ft C +RNAinverse \-R 5 +.ft +.br +and enter the lines +.br +.ft C +(((.(((....))).))) +.br +NNNgNNNNNNNNNNaNNN +.ft + +.SH "REFERENCES" +The calculation of minimum free energy structures is based on dynamic +programming algorithm originally developed by M. Zuker and P. Stiegler. +The partition function algorithm is based on work by J.S. McCaskill. +.br +If this Program proves useful for your work please cite: +.PP +I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. Schuster +(1994) +Fast Folding and Comparison of RNA Secondary Structures. +Monatshefte f. Chemie 125: 167\-188 +.br +Other useful references are: +.br +M. Zuker, P. Stiegler (1981) Optimal computer folding of large RNA +sequences using thermodynamic and auxiliary information, Nucl Acid Res +9: 133\-148 +.br +J.S. McCaskill (1990) The equilibrium partition function and base pair +binding probabilities for RNA secondary structures, Biopolymers 29: 1105\-1119 +.br +D.H. Turner N. Sugimoto and S.M. Freier (1988) RNA structure +prediction, Ann Rev Biophys Biophys Chem 17: 167\-192 +.br +D. Adams (1979) The hitchhiker's guide to the galaxy, Pan Books, London +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHOR" +Ivo L Hofacker. +.SH "BUGS" +If in doubt our program is right, nature is at fault. +Comments should be sent to rna@tbi.univie.ac.at. +.br diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.info b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.info new file mode 100755 index 00000000..60e7247f --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.info @@ -0,0 +1,1430 @@ +This is RNAlib.info, produced by makeinfo version 4.8 from +RNAlib.texinfo. + + +File: RNAlib.info, Node: Top, Next: Introduction, Prev: (dir), Up: (dir) + + This file documents the Vienna RNA Package Version 1.6 + + Copyright (C)1994-2002 Ivo Hofacker and Peter Stadler + +* Menu: + +* Introduction:: +* Folding Routines:: Functions for Folding RNA Secondary Structures +* Parsing and Comparing:: Functions to Manipulate Structures +* Utilities:: Odds and Ends +* Example:: A Small Example Program +* References:: +* Function Index:: +* Variable Index:: + + +File: RNAlib.info, Node: Introduction, Next: Folding Routines, Prev: Top, Up: Top + +1 Introduction +************** + +The core of the Vienna RNA Package is formed by a collection of routines +for the prediction and comparison of RNA secondary structures. These +routines can be accessed through stand-alone programs, such as RNAfold, +RNAdistance etc., which should be sufficient for most users. For those +who wish to develop their own programs we provide a library which can be +linked to your own code. + + This document describes the library and will be primarily useful to +programmers. However, it also contains details about the implementation +that may be of interest to advanced users. The stand-alone programs are +described in separate man pages. The latest version of the package +including source code and html versions of the documentation can be +found at `http://www.tbi.univie.ac.at/~ivo/RNA/'. This manual +documents version 1.6. + + Please send comments and bug reports to . + + +File: RNAlib.info, Node: Folding Routines, Next: Parsing and Comparing, Prev: Introduction, Up: Top + +2 Folding Routines +****************** + +* Menu: + +* mfe Fold:: Calculating Minimum Free Energy Structures +* PF Fold:: Calculating Partition Functions and Pair Probabilities +* Inverse Fold:: Searching for Predefined Structures +* Suboptimal folding:: Enumerating Suboptimal Structures +* Cofolding:: Folding of 2 RNA molecules +* Local Fold:: Predicting local structures of large sequences +* Alignment Fold:: Predicting Consensus Structures from Alignment +* Fold Vars:: Global Variables for the Folding Routines +* Param Files:: Reading Energy Parameters from File + + +File: RNAlib.info, Node: mfe Fold, Next: PF Fold, Prev: Folding Routines, Up: Folding Routines + +2.1 Minimum free Energy Folding +=============================== + +The library provides a fast dynamic programming minimum free energy +folding algorithm as described by `Zuker & Stiegler (1981)'. +Associated functions are: + + -- Function: float fold (char* SEQUENCE, char* STRUCTURE) + folds the SEQUENCE and returns the minimum free energy in kcal/mol; + the mfe structure in bracket notation (*note notations::) is + returned in STRUCTURE. Sufficient space for string of the same + length as SEQUENCE must be allocated for STRUCTURE before calling + `fold()'. If `fold_constrained' (*note Variables: Fold Vars.) is + 1, the STRUCTURE string is interpreted on input as a list of + constraints for the folding. The characters " | x < > " mark bases + that are paired, unpaired, paired upstream, or downstream, + respectively; matching brackets " ( ) " denote base pairs, dots + "." are used for unconstrained bases. Constrained folding works by + assigning bonus energies to all structures that comply with the + constraint. + + -- Function: float energy_of_struct (char* SEQUENCE, char* STRUCTURE) + calculates the energy of SEQUENCE on the STRUCTURE + + -- Function: void initialize_fold (int LENGTH) + Obsolete function kept for backward compatibility. Allocates + memory for mfe folding sequences not longer than LENGTH, and sets + up pairing matrix and energy parameters. + + -- Function: void free_arrays () + frees the memory allocated by `fold()'. + + -- Function: void update_fold_params () + call this to recalculate the pair matrix and energy parameters + after a change in folding parameters like `temperature' (*note + Variables: Fold Vars.). + + Prototypes for these functions are declared in `fold.h'. + + +File: RNAlib.info, Node: PF Fold, Next: Inverse Fold, Prev: mfe Fold, Up: Folding Routines + +2.2 Partition Function Folding +============================== + +Instead of the minimum free energy structure the partition function of +all possible structures and from that the pairing probability for every +possible pair can be calculated, using a dynamic programming algorithm +as described by `McCaskill (1990)'. The following functions are +provided: + + -- Function: float pf_fold (char* SEQUENCE, char* STRUCTURE) + calculates the partition function Z of SEQUENCE and returns the + free energy of the ensemble F in kcal/mol, where F=-kT ln(Z). If + STRUCTURE is not a NULL pointer on input, it contains on return a + string consisting of the letters " . , | { } ( ) " denoting bases + that are essentially unpaired, weakly paired, strongly paired + without preference, weakly upstream (downstream) paired, or + strongly up- (down-)stream paired bases, respectively. If + `fold_constrained' (*note Variables: Fold Vars.) is 1, the + STRUCTURE string is interpreted on input as a list of constraints + for the folding. The character "x" marks bases that must be + unpaired, matching brackets " ( ) " denote base pairs, all other + characters are ignored. Any pairs conflicting with the constraint + will be forbidden. This usually sufficient to ensure the + constraints are honored. If `do_backtrack' (*note Variables: Fold + Vars.) has been set to 0 base pairing probabilities will not be + computed (saving CPU time), otherwise the `pr[iindx[i]-j]' (*note + Variables: Fold Vars.) will contain the probability that bases i + and j pair. + + -- Function: void init_pf_fold (int LENGTH) + allocates memory for folding sequences not longer than LENGTH; + sets up pairing matrix and energy parameters. Has to be called + before the first call to `pf_fold()'. + + -- Function: void free_pf_arrays (void) + frees the memory allocated by `init_pf_fold()'. + + -- Function: void update_pf_params (int LENGTH) + Call this function to recalculate the pair matrix and energy + parameters after a change in folding parameters like temperature + (*note Variables: Fold Vars.). + + -- Function: double mean_bp_dist (int LENGTH) + computes the mean base pair distance in the equilibrium ensemble + as a measure of the structural diversity. It is given by = + sum_a,b p_a * p_b * d(a,b), where the sum goes over all pairs of + possible structure a,b, p_a is the Boltzmann weight of structure + a, and d(a,b) is the base pair distance (see `bp_distance()' in + *Note Distances::.). The mean base pair distances can be computed + efficiently from the pair probabilities p_ij as = sum_ij p_ij + * (1-p_ij). Uses the global `pr' array filled by a previous call + to `pf_fold()'. + + Prototypes for these functions are declared in `part_func.h'. + + +File: RNAlib.info, Node: Inverse Fold, Next: Suboptimal folding, Prev: PF Fold, Up: Folding Routines + +2.3 Inverse Folding +=================== + +We provide two functions that search for sequences with a given +structure, thereby inverting the folding routines. + + -- Function: float inverse_fold (char* START, char* TARGET) + searches for a sequence with minimum free energy structure TARGET, + starting with sequence START. It returns 0 if the search was + successful, otherwise a structure distance to TARGET is returned. + The found sequence is returned in START. If `give_up' is set to 1, + the function will return as soon as it is clear that the search + will be unsuccessful, this speeds up the algorithm if you are only + interested in exact solutions. Since `inverse_fold()' calls + `fold()' you have to allocate memory for folding by calling + `initialize_fold()' + + -- Function: float inverse_pf_fold (char* START, char* TARGET) + searches for a sequence with maximum probability to fold into + structure TARGET using the partition function algorithm. It returns + -kT log(p) where p is the frequency of TARGET in the ensemble of + possible structures. This is usually much slower than + `inverse_fold()'. Since `inverse_pf_fold()' calls `pf_fold()' you + have to allocate memory for folding by calling `init_pf_fold()' + + -- Variable: char *symbolset + The global variable `char *symbolset' points to the allowed bases, + initially `"AUGC"'. It can be used to design sequences from + reduced alphabets. + + Prototypes for these functions are declared in `inverse.h'. + + +File: RNAlib.info, Node: Suboptimal folding, Next: Cofolding, Prev: Inverse Fold, Up: Folding Routines + +2.4 Suboptimal folding +====================== + + -- data type: SOLUTION struct {float energy; char *structure;} + + -- Function: SOLUTION* subopt (char* SEQUENCE, char* CONSTRAINT, int* + DELTA, FILE* FP) + poduces *all* suboptimal secondary structures within DELTA*0.01 + kcal/mol of the optimum. The reults are either directly written to + a FP (if FP is not `NULL'), or (FP`==NULL') returned in a + `SOLUTION *' list terminated by an entry were the `structure' + pointer is `NULL'. + + Prototypes for these functions are declared in `subopt.h'. + + +File: RNAlib.info, Node: Cofolding, Next: Local Fold, Prev: Suboptimal folding, Up: Folding Routines + +2.5 Predicting hybridization structures of two molecules +======================================================== + +The function of an RNA molecule often depends on its interaction with +other RNAs. The following routines therefore allow to predict structures +formed by two RNA molecules upon hybridization. One approach to +co-folding two RNAs consists of concatenating the two sequences and +keeping track of the concatenation point in all energy evaluations. +Correspondingly, many of the `cofold()' and `co_pf_fold()' routines +below take one sequence string as argument and use the the global +variable CUT_POINT to mark the concatenation point. Note that while the +`RNAcofold' program uses the '&' character to mark the chain break in +its input, you should not use an '&' when using the library routines +(set CUT_POINT instead). + + -- Variable: int cut_point + `cut_point' marks the position (starting from 1) of the first + nucleotide of the second molecule within the concatenated sequence. + The default value of -1 stands for single molecule folding. The + `cut_point' variable is also used by `PS_rna_plot()' and + `PS_dot_plot()' to mark the chain break in postscript plots. + + -- Function: float cofold (char *SEQUENCE, char *STRUCTURE) + The analog to the `fold()' function. Computes the minimum free + energy of two RNA molecules interacting. If `cut_point==-1' results + should be the same as with `fold()'. + + -- Function: void free_co_arrays (void) + Frees arrays allocated by `cofold()'. + + -- Function: void initialize_cofold (int LENGTH) + Allocates memory for mfe cofolding sequences not longer than + LENGTH, and sets up pairing matrix and energy parameters. + Explicitely calling `initialize_cofold()' is normally not + necessary, as it will be called automagically before folding. + + Prototypes for these functions are declared in `cofold.h'. + +2.6 Partition Function Cofolding +================================ + +As for folding one RNA molecule, this computes the partition function +of all possible structures and the base pair probabilities. Uses the +same global PF_SCALE variable to avoid overflows. + + To simplify the implementation the partition function computation is +done internally in a null model that does not include the duplex +initiation energy, i.e. the entropic penalty for producing a dimer from +two monomers). The resulting free energies and pair probabilities are +initally relative to that null model. In a second step the free +energies can be corrected to include the dimerization penalty, and the +pair probabilities can be divided into the conditional pair +probabilities given that a re dimer is formed or not formed. + + -- data type: cofoldF struct {double F0AB, FAB, FcAB, FA, FB;} + + -- Function: cofoldF co_pf_fold (char* SEQUENCE, char* STRUCTURE) + The analog to the `pf_fold()' function, it computes the partition + function of two interacting RNA molecules as well as base pair + probabilities. It returns a struct including free energies + computed for different models. F0AB is the free energy in the null + model; FAB is corrected to include the initiation penalty, FcAB + only includes real dimers. FA and FB are the free energies of the + 2 molecules, resp. As with `cofold()' the CUT_POINT global + variable has to be set to mark the chain break between the + molecules. + + -- Function: void free_co_pf_arrays (void) + frees partition function cofold arrays allocated in ` + co_pf_fold()'. + + -- Function: void init_co_pf_fold (int LENGTH) + Obsolete function kept for backward compatibility. Allocates + memory for partition function cofolding sequences not longer than + LENGTH, and sets up pairing matrix and energy parameters. + + -- data type: plist struct {int i; int j; float energy;} + + -- Function: extern struct plist *get_plist (struct plist *PL, int + LENGTH, double CUT_OFF) + Makes a list of base pairs out of the global *PR array, ignoring + all base pairs with a probability less than CUT_OFF. This is + useful since the PR array gets overwritten by subsequent foldings. + + Prototypes for these functions are declared in `co_part_func.h'. + +2.7 Cofolding all Dimeres, Concentrations +========================================= + +After computing the partition functions of all possible dimeres one can +compute the probabilities of base pairs, the concentrations out of +start concentrations and sofar and soaway. + + -- Function: void compute_probabilities (double FAB, double FEA, + double FEB, struct plist *PRAB, struct plist *PRA, struct + plist *PRB, int ALENGTH) + Given the pair probabilities and free energies (in the null model) + for a dimer AB and the two constituent monomers A and B, compute + the conditional pair probabilities given that a dimer AB actually + forms. Null model pair probabilities are given as a list as + produced by `get_plist()'), the dimer probabilities PRAB are + modified in place. + + Dimer formation is inherently concentration dependent. Given the free +energies of the monomers A and B and dimers AB, AA, and BB one can +compute the equilibrium concentrations, given input concentrations of A +and B, see e.g.~`Dimitrov & Zuker (2004)' + + -- data type: ConcEnt struct {double A0; double B0;double ABc;double + AAc; double BBc; double Ac; double Bc;} + + -- Function: extern struct ConcEnt *get_concentrations(double FEAB, + double FEAA, double FEBB, double FEA, double FEB, double * + STARTCONC) + Takes an array STARTCONC of input concentrations with alternating + entries for the initial concentrations of molecules A and B + (terminated by two zeroes), then computes the resulting + equilibrium concentrations from the free energies for the dimers. + Dimer free energies should be the dimer-only free energies, i.e. + the FcAB entries from the `cofoldF' struct. + + Prototypes for these functions are declared in `co_part_func.h'. + + +File: RNAlib.info, Node: Local Fold, Next: Alignment Fold, Prev: Cofolding, Up: Folding Routines + +2.8 Searching for local mfe structures in large molecules +========================================================= + +Local structures can be predicted by a modified version of the `fold()' +algorithm that restricts the span of all base pairs. + + -- Function: float Lfold (char *STRING, char *STRUCTURE, int MAXDIST) + The local analog to `fold()'. Computes the minimum free energy + structure including only base pairs with a span smaller than + + MAXDIST. + + -- Function: int pfl_fold (char *SEQUENCE, int WINSIZE, float CUTOFF, + struct plist **PL) + pfl_fold computes partition functions for every window of size + WINSIZE possible in a RNA molecule, and returns the mean base pair + probabilities in PL. Note that in contrast to `Lfold()', bases + outside of the window do not influence the structure at all. Only + probabilities higher than CUTOFF are kept. + + -- Function: void init_pf_foldLP (int LENGTH) + Analog to `init_pf_fold()'. LENGTH is the length of the sequence. + + -- Function: void free_pf_arraysLP (void) + frees the arrays used by `pfl_fold()' + + -- Function: void update_pf_paramsLP (int LENGTH) + Analog to `update_pf_params()'. LENGTH is the length of the + sequence. + + +File: RNAlib.info, Node: Alignment Fold, Next: Fold Vars, Prev: Local Fold, Up: Folding Routines + +2.9 Predicting Consensus Structures from an Alignment +===================================================== + +Consensus structures can be predicted by a modified version of the +`fold()' algorithm that takes a set of aligned sequences instead of a +single sequence. The energy function consists of the mean energy +averaged over the sequences, plus a covariance term that favors pairs +with consistent and compensatory mutations and penalizes pairs that +cannot be formed by all structures. For details see `Hofacker (2002)'. + + -- Function: float alifold (char** SEQUENCES, char* STRUCTURE) + Predicts the consensus structure for the aligned SEQUENCES and + returns the minimum free energy; the mfe structure in bracket + notation (*note notations::) is returned in STRUCTURE. Sufficient + space must be allocated for STRUCTURE before calling `alifold()'. + + -- Function: void free_alifold_arrays () + frees the memory allocated by `alifold()'. + + -- Function: void update_alifold_params () + call this to recalculate the pair matrix and energy parameters + after a change in folding parameters like `temperature' (*note + Variables: Fold Vars.). + + -- Function: float alipf_fold (char** SEQUENCES, char* STRUCTURE, + pair_info **PI) + The partition function version of `alifold()' works in analogy to + `pf_fold()'. Pair probabilities and information about sequence + covariations are returned via the PI variable as a list of + `pair_info' structs. The list is terminated by the first entry + with `pi.i = 0'. + + -- data type: pair_info struct {short i,j; float p; float ent; short + bp[8]; char comp;} + for each base pair `i,j' the structure lists: its probability `p', + an entropy-like measure for its well-definedness `ent', and in + `bp[]' the frequency of each type of pair. `bp[0]' contains the + number of non-compatible sequences, `bp[1]' the number of CG + pairs, etc. + + -- Variable: double cv_fact + `cv_fact' controls the weight of the covariance term in the energy + function. Default is 1. + + -- Variable: double nc_fact + controls the magnitude of the penalty for non-compatible sequences + in the covariance term. Default is 1. + + +File: RNAlib.info, Node: Fold Vars, Next: Param Files, Prev: Alignment Fold, Up: Folding Routines + +2.10 Global Variables for the Folding Routines +============================================== + +The following global variables change the behavior the folding +algorithms or contain additional information after folding. + + -- Variable: int noGU + do not allow GU pairs if equal 1; default is 0. + + -- Variable: int no_closingGU + if 1 allow GU pairs only inside stacks, not as closing pairs; + default is 0. + + -- Variable: int noLonelyPairs + Disallow all pairs which can *only* occur as lonely pairs (i.e. as + helix of length 1). This avoids lonely base pairs in the predicted + structures in most cases. + + -- Variable: int tetra_loop + include special stabilizing energies for some tetra loops; default + is 1. + + -- Variable: int energy_set + if 1 or 2: fold sequences from an artificial alphabet ABCD..., + where A pairs B, C pairs D, etc. using either GC (1) or AU + parameters (2); default is 0, you probably don't want to change it. + + -- Variable: float temperature + rescale energy parameters to a temperature of `temperature' C. + Default is 37C. You have to call the update_..._params() functions + after changing this parameter. + + -- Variable: int dangles + if set to 0 no stabilizing energies are assigned to bases adjacent + to helices in free ends and multiloops (so called dangling ends). + Normally (`dangles = 1') dangling end energies are assigned only + to unpaired bases and a base cannot participate simultaneously in + two dangling ends. In the partition function algorithm `pf_fold()' + these checks are neglected. If `dangles' is set to 2, the + `fold()' and `energy_of_struct()' function will also follow this + convention. This treatment of dangling ends gives more favorable + energies to helices directly adjacent to one another, which can be + beneficial since such helices often do engage in stabilizing + interactions through co-axial stacking. + If `dangles = 3' co-axial stacking is explicitly included for + adjacent helices in mutli-loops. The option affects only mfe + folding and energy evaluation (`fold()' and `energy_of_struct()'), + as well as suboptimal folding (`subopt()') via re-evaluation of + energies. Co-axial stacking with one intervening mismatch is not + considered so far. + + Default is 1, `pf_fold()' treats 1 as 2. + + -- Variable: char* nonstandards + Lists additional base pairs that will be allowed to form in + addition to GC, CG, AU, UA, GU and UG. Nonstandard base pairs are + given a stacking energy of 0. + + -- Variable: int cut_point + To evaluate the energy of a duplex structure (a structure formed + by two strands), concatenate the to sequences and set CUT_POINT to + the first base of the second strand in the concatenated sequence. + Reset to 0 or -1 (the default) to evaluate normal single sequence + structures. + + -- Variable: struct bond { int i,j;} base_pair + Contains a list of base pairs after a call to `fold()'. + `base_pair[0].i' contains the total number of pairs. + + -- Variable: double* pr + contains the base pair probability matrix after a call to + `pf_fold()'. + + -- Variable: int* iindx + index array to move through pr. The probability for base i and j + to form a pair is in `pr[iindx[i]-j]'. + + -- Variable: float pf_scale + a scaling factor used by `pf_fold()' to avoid overflows. Should be + set to approximately exp((-F/kT)/length), where F is an estimate + for the ensemble free energy, for example the minimum free energy. + You must call `update_pf_params()' or `init_pf_fold()' after + changing this parameter. If pf_scale is -1 (the default) , an + estimate will be provided automatically when calling + `init_pf_fold()' or `update_f_params()'. The automatic estimate is + usually insufficient for sequences more than a few hundred bases + long. + + -- Variable: int fold_constrained + If 1, calculate constrained minimum free energy structures. *Note + mfe Fold::, for more information. Default is 0; + + -- Variable: int do_backtrack + if 0, do not calculate pair probabilities in `pf_fold()'; this is + about twice as fast. Default is 1. + + -- Variable: char backtrack_type + only for use by `inverse_fold()'; 'C': force (1,N) to be paired, + 'M' fold as if the sequence were inside a multi-loop. Otherwise the + usual mfe structure is computed. + + include `fold_vars.h' if you want to change any of these variables +from their defaults. + + +File: RNAlib.info, Node: Param Files, Prev: Fold Vars, Up: Folding Routines + +2.11 Energy Parameter Files +=========================== + +A default set of parameters, identical to the one described in `Mathews +et.al. (1999)', is compiled into the library. Alternately, parameters +can be read from and written to a file. + + -- Function: void read_parameter_file (const char FNAME[]) + reads energy parameters from file FNAME. See below for the format + of the parameter file. + + -- Function: void write_parameter_file (const char FNAME[]) + writes current energy parameters to the file FNAME. + + The following describes the file format expected by +`read_parameter_file()'. All energies should be given as integers in +units of 0.01kcal/mol. + + Various loop parameters depend in general on the pairs closing the +loops, as well as unpaired bases in the loops. Internally, the library +distinguishes 8 types of pairs (CG=1, GC=2, GU=3, UG=4, AU=5, UA=6, +nonstandard=7, 0= no pair), and 5 types of bases (A=1, C=2, G=3, U=4 +and 0 for anything else). Parameters belonging to pairs of type 0 are +not listed in the parameter files, but values for nonstandard pairs +(type 7) and nonstandard bases (type 0) are. Thus, a table for +symmetric size 2 interior loops would have 7*7*5*5 entries (2 pairs, +two unpaired bases). + + The order of entries always uses the closing pair or pairs as the +first indices followed by the unpaired bases in 5' to 3' direction. To +determine the type of a pair consider the base at the (local) 5' end of +each strand first, i.e. use the pairs (i,j) and (q,p) for an interior +loop with i + #include + #include "utils.h" + #include "fold_vars.h" + #include "fold.h" + #include "part_func.h" + #include "inverse.h" + #include "RNAstruct.h" + #include "treedist.h" + #include "stringdist.h" + #include "profiledist.h" + + void main() + { + char *seq1="CGCAGGGAUACCCGCG", *seq2="GCGCCCAUAGGGACGC", + *struct1,* struct2,* xstruc; + float e1, e2, tree_dist, string_dist, profile_dist, kT; + Tree *T1, *T2; + swString *S1, *S2; + float **pf1, **pf2; + + /* fold at 30C instead of the default 37C */ + temperature = 30.; /* must be set *before* initializing */ + /* allocate memory for fold(), could be skipped */ + initialize_fold(strlen(seq1)); + + /* allocate memory for structure and fold */ + struct1 = (char* ) space(sizeof(char)*(strlen(seq1)+1)); + e1 = fold(seq1, struct1); + + struct2 = (char* ) space(sizeof(char)*(strlen(seq2)+1)); + e2 = fold(seq2, struct2); + + free_arrays(); /* free arrays used in fold() */ + + /* produce tree and string representations for comparison */ + xstruc = expand_Full(struct1); + T1 = make_tree(xstruc); + S1 = Make_swString(xstruc); + free(xstruc); + + xstruc = expand_Full(struct2); + T2 = make_tree(xstruc); + S2 = Make_swString(xstruc); + free(xstruc); + + /* calculate tree edit distance and aligned structures with gaps */ + edit_backtrack = 1; + tree_dist = tree_edit_distance(T1, T2); + free_tree(T1); free_tree(T2); + unexpand_aligned_F(aligned_line); + printf("%s\n%s %3.2f\n", aligned_line[0], aligned_line[1], tree_dist); + + /* same thing using string edit (alignment) distance */ + string_dist = string_edit_distance(S1, S2); + free(S1); free(S2); + printf("%s mfe=%5.2f\n%s mfe=%5.2f dist=%3.2f\n", + aligned_line[0], e1, aligned_line[1], e2, string_dist); + + /* for longer sequences one should also set a scaling factor for + partition function folding, e.g: */ + kT = (temperature+273.15)*1.98717/1000.; /* kT in kcal/mol */ + pf_scale = exp(-e1/kT/strlen(seq1)); + init_pf_fold(strlen(seq1)); + + /* calculate partition function and base pair probabilities */ + e1 = pf_fold(seq1, struct1); + pf1 = Make_bp_profile(strlen(seq1)); + + e2 = pf_fold(seq2, struct2); + pf2 = Make_bp_profile(strlen(seq2)); + + free_pf_arrays(); /* free space allocated for pf_fold() */ + + profile_dist = profile_edit_distance(pf1, pf2); + printf("%s free energy=%5.2f\n%s free energy=%5.2f dist=%3.2f\n", + aligned_line[0], e1, aligned_line[1], e2, profile_dist); + + free_profile(pf1); free_profile(pf2); + } + + In a typical Unix environment you would compile this program using: +`cc -c example.c -IHPATH' and link using `cc -o example -LLPATH -lRNA +-lm' where HPATH and LPATH point to the location of the header files +and library, respectively. + + +File: RNAlib.info, Node: References, Next: Function Index, Prev: Example, Up: Top + +6 References +************ + + - D.H. Mathews, J. Sabina, M. Zucker and H. Turner (1999) + Expanded sequence dependence of thermodynamic parameters provides + robust prediction of RNA secondary structure, JMB, 288: 911-940 + + - M. Zuker and P. Stiegler (1981) + Optimal computer folding of large RNA sequences using + thermodynamic and auxiliary information, Nucl Acid Res 9: 133-148 + + - D.A. Dimitrov, M.Zuker(2004) + Prediction of hybridization and melting for double stranded nucleic + acids, Biophysical J. 87: 215-226, + + - J.S. McCaskill (1990) + The equilibrium partition function and base pair binding + probabilities for RNA secondary structures, Biopolymers 29: + 1105-1119 + + - D.H. Turner, N. Sugimoto and S.M. Freier (1988) + RNA structure prediction, Ann Rev Biophys Biophys Chem 17: 167-192 + + - J.A. Jaeger, D.H. Turner and M. Zuker (1989) + Improved predictions of secondary structures for RNA, Proc. + Natl. Acad. Sci. 86: 7706-7710 + + - L. He, R. Kierzek, J. SantaLucia, A.E. Walter and D.H. Turner + (1991) + Nearest-Neighbor Parameters For GU Mismatches, Biochemistry 30: + 11124-11132 + + - A.E. Peritz, R. Kierzek, N, Sugimoto, D.H. Turner (1991) + Thermodynamic Study of Internal Loops in Oligoribonucleotides ... , + Biochemistry 30: 6428-6435 + + - A. Walter, D. Turner, J. Kim, M. Lyttle, P. Mu"ller, D. Mathews + and M. Zuker (1994) + Coaxial stacking of helices enhances binding of + Oligoribonucleotides.., Proc. Natl. Acad. Sci. 91: 9218-9222 + + - B.A. Shapiro, (1988) + An algorithm for comparing multiple RNA secondary structures, + CABIOS 4, 381-393 + + - B.A. Shapiro and K. Zhang (1990) + Comparing multiple RNA secondary structures using tree comparison, + CABIOS 6, 309-318 + + - R. Bruccoleri and G. Heinrich (1988) + An improved algorithm for nucleic acid secondary structure display, + CABIOS 4, 167-173 + + - W. Fontana , D.A.M. Konings, P.F. Stadler, P. Schuster (1993) + Statistics of RNA secondary structures, Biopolymers 33, 1389-1404 + + - W. Fontana, P.F. Stadler, E.G. Bornberg-Bauer, T. Griesmacher, I.L. + Hofacker, M. Tacker, P. Tarazona, E.D. Weinberger, P. Schuster + (1993) + RNA folding and combinatory landscapes, Phys. Rev. E 47: 2083-2099 + + - I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, + P. Schuster (1994) Fast Folding and Comparison of RNA + Secondary Structures. Monatshefte f. Chemie 125: 167-188 + + - I.L. Hofacker (1994) The Rules of the Evolutionary Game for RNA: + A Statistical Characterization of the Sequence to Structure + Mapping in RNA. PhD Thesis, University of Vienna. + + - I.L. Hofacker, M. Fekete, P.F. Stadler (2002). Secondary + Structure Prediction for Aligned RNA Sequences. J. Mol. Biol. + 319:1059-1066 + + - D. Adams (1979) + The hitchhiker's guide to the galaxy, Pan Books, London + + +File: RNAlib.info, Node: Function Index, Next: Variable Index, Prev: References, Up: Top + +Function Index +************** + +[index] +* Menu: + +* add_root: Parsing. (line 31) +* alifold: Alignment Fold. (line 14) +* alipf_fold: Alignment Fold. (line 29) +* b2C: Parsing. (line 18) +* b2HIT: Parsing. (line 14) +* b2Shapiro: Parsing. (line 22) +* bp_distance: Distances. (line 20) +* co_pf_fold: Cofolding. (line 60) +* cofold: Cofolding. (line 26) +* compute_probabilities: Cofolding. (line 99) +* energy_of_struct: mfe Fold. (line 25) +* expand_Full: Parsing. (line 10) +* expand_Shapiro: Parsing. (line 27) +* fold: mfe Fold. (line 11) +* free_alifold_arrays: Alignment Fold. (line 20) +* free_arrays: mfe Fold. (line 33) +* free_co_arrays: Cofolding. (line 31) +* free_co_pf_arrays: Cofolding. (line 71) +* free_pf_arrays: PF Fold. (line 38) +* free_pf_arraysLP: Local Fold. (line 27) +* free_profile: Profile Distances. (line 20) +* free_tree: Tree Distances. (line 15) +* get_line: Utilities. (line 98) +* gmlRNA: Utilities. (line 39) +* hamming: Utilities. (line 56) +* init_co_pf_fold: Cofolding. (line 75) +* init_pf_fold: PF Fold. (line 33) +* init_pf_foldLP: Local Fold. (line 24) +* initialize_cofold: Cofolding. (line 34) +* initialize_fold: mfe Fold. (line 28) +* int_urn: Utilities. (line 91) +* inverse_fold: Inverse Fold. (line 10) +* inverse_pf_fold: Inverse Fold. (line 21) +* Lfold: Local Fold. (line 10) +* Make_bp_profile: Profile Distances. (line 10) +* make_pair_table: Utilities. (line 71) +* Make_swString: String Distances. (line 7) +* make_tree: Tree Distances. (line 7) +* mean_bp_dist: PF Fold. (line 46) +* nrerror: Utilities. (line 80) +* pack_structure: Utilities. (line 60) +* parse_structure: Parsing. (line 48) +* pf_fold: PF Fold. (line 13) +* pfl_fold: Local Fold. (line 17) +* profile_edit_distance: Profile Distances. (line 17) +* PS_dot_plot: Utilities. (line 9) +* PS_rna_plot: Utilities. (line 19) +* PS_rna_plot_a: Utilities. (line 27) +* random_string: Utilities. (line 52) +* read_parameter_file: Param Files. (line 11) +* space: Utilities. (line 94) +* string_edit_distance: String Distances. (line 11) +* struct: Cofolding. (line 83) +* subopt: Suboptimal folding. (line 10) +* svg_RNA_plot: Utilities. (line 34) +* time_stamp: Utilities. (line 76) +* tree_edit_distance: Tree Distances. (line 12) +* unexpand_aligned_F: Parsing. (line 43) +* unexpand_Full: Parsing. (line 34) +* unpack_structure: Utilities. (line 67) +* unweight: Parsing. (line 38) +* update_alifold_params: Alignment Fold. (line 23) +* update_fold_params: mfe Fold. (line 36) +* update_pf_params: PF Fold. (line 41) +* update_pf_paramsLP: Local Fold. (line 30) +* urn: Utilities. (line 83) +* write_parameter_file: Param Files. (line 15) + + +File: RNAlib.info, Node: Variable Index, Prev: Function Index, Up: Top + +Variable Index +************** + +[index] +* Menu: + +* *symbolset: Inverse Fold. (line 29) +* aligned_line: Distances. (line 76) +* backtrack_type: Fold Vars. (line 100) +* base_pair: Fold Vars. (line 69) +* cost_matrix: Distances. (line 68) +* cut_point <1>: Fold Vars. (line 62) +* cut_point: Cofolding. (line 19) +* cv_fact: Alignment Fold. (line 44) +* dangles: Fold Vars. (line 36) +* do_backtrack: Fold Vars. (line 96) +* edit_backtrack: Distances. (line 72) +* energy_set: Fold Vars. (line 26) +* fold_constrained: Fold Vars. (line 92) +* give_up: Inverse Fold. (line 13) +* helix_size: Parsing. (line 59) +* iindx: Fold Vars. (line 77) +* loop_degree: Parsing. (line 56) +* loop_size: Parsing. (line 52) +* loops: Parsing. (line 62) +* nc_fact: Alignment Fold. (line 48) +* no_closingGU: Fold Vars. (line 13) +* noGU: Fold Vars. (line 10) +* noLonelyPairs: Fold Vars. (line 17) +* nonstandards: Fold Vars. (line 57) +* pairs: Parsing. (line 65) +* pf_scale: Fold Vars. (line 81) +* pr: Fold Vars. (line 73) +* rna_plot_type: Utilities. (line 46) +* temperature: Fold Vars. (line 31) +* tetra_loop: Fold Vars. (line 22) +* unpaired: Parsing. (line 68) +* xsubi: Utilities. (line 87) + + + +Tag Table: +Node: Top76 +Node: Introduction601 +Node: Folding Routines1611 +Node: mfe Fold2422 +Node: PF Fold4292 +Node: Inverse Fold7222 +Node: Suboptimal folding8859 +Node: Cofolding9538 +Node: Local Fold15647 +Node: Alignment Fold16981 +Node: Fold Vars19306 +Node: Param Files23925 +Node: Parsing and Comparing31238 +Node: notations31648 +Node: Parsing35171 +Node: Distances37812 +Node: Tree Distances41675 +Node: String Distances42453 +Node: Profile Distances42983 +Node: Utilities44062 +Node: Example48698 +Node: References52197 +Node: Function Index55243 +Node: Variable Index60283 + +End Tag Table diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.texinfo b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.texinfo new file mode 100755 index 00000000..81c2e791 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAlib.texinfo @@ -0,0 +1,1428 @@ +\input texinfo @c -*- Mode: texinfo; fill-column: 74 -*- +@c Last changed Time-stamp: <2006-01-19 12:27:59 ivo> +@set revision $Id: RNAlib.texinfo,v 1.17 2006/01/19 11:28:40 ivo Exp $ +@setfilename RNAlib.info +@settitle Vienna RNA Package +@ifclear Version +@set Version 1.6 +@end ifclear +@iftex +@afourpaper +@end iftex +@ifinfo +@setchapternewpage odd +@end ifinfo +@titlepage +@sp 10 +@title{Vienna RNA Package} +@sp +@subtitle{A Library for folding and comparing RNA secondary structures} + +@vskip 0pt plus 1filll +Copyright @copyright{1994-2002} @author{Ivo Hofacker and Peter Stadler} +@c @smallexample +Revision @value{revision} +@c @end smallexample +@end titlepage + +@node Top, Introduction, (dir), (dir) +@comment node-name, next, previous, up + +@ifinfo +This file documents the Vienna RNA Package Version @value{Version} + +Copyright @copyright{1994-2002} Ivo Hofacker and Peter Stadler +@end ifinfo + +@menu +* Introduction:: +* Folding Routines:: Functions for Folding RNA Secondary Structures +* Parsing and Comparing:: Functions to Manipulate Structures +* Utilities:: Odds and Ends +* Example:: A Small Example Program +* References:: +* Function Index:: +* Variable Index:: +@end menu + +@node Introduction, Folding Routines, Top, Top +@chapter Introduction + +The core of the Vienna RNA Package is formed by a collection of routines +for the prediction and comparison of RNA secondary structures. These +routines can be accessed through stand-alone programs, such as RNAfold, +RNAdistance etc., which should be sufficient for most users. For those who +wish to develop their own programs we provide a library which can be +linked to your own code. + +This document describes the library and will be primarily useful to +programmers. However, it also contains details about the implementation +that may be of interest to advanced users. The stand-alone programs are +described in separate man pages. The latest version of the package +including source code and html versions of the documentation can be found +at +@ifclear texi2html +@url{http://www.tbi.univie.ac.at/~ivo/RNA/}. +@end ifclear +@ifset texi2html +@ifhtml +the ViennaRNA page. +@end ifhtml +@end ifset +This manual documents version @value{Version}. + +Please send comments and bug reports to +@ifclear texi2html +@email{ivo@@tbi.univie.ac.at}. +@end ifclear +@ifset texi2html +@ifhtml +<Ivo.Hofacker@tbi.univie.ac.at>. +@end ifhtml +@end ifset + +@node Folding Routines, Parsing and Comparing, Introduction, Top +@comment node-name, next, previous, up +@chapter Folding Routines + +@menu +* mfe Fold:: Calculating Minimum Free Energy Structures +* PF Fold:: Calculating Partition Functions and Pair Probabilities +* Inverse Fold:: Searching for Predefined Structures +* Suboptimal folding:: Enumerating Suboptimal Structures +* Cofolding:: Folding of 2 RNA molecules +* Local Fold:: Predicting local structures of large sequences +* Alignment Fold:: Predicting Consensus Structures from Alignment +* Fold Vars:: Global Variables for the Folding Routines +* Param Files:: Reading Energy Parameters from File +@end menu + +@node mfe Fold, PF Fold, Folding Routines, Folding Routines + +@section Minimum free Energy Folding +The library provides a fast dynamic programming minimum free energy +folding algorithm as described by @cite{Zuker & Stiegler (1981)}. +Associated functions are: + + +@deftypefun float fold (char* @var{sequence}, char* @var{structure}) +folds the @var{sequence} and returns the minimum free energy in kcal/mol; +the mfe structure in bracket notation (@pxref{notations}) is returned in +@var{structure}. Sufficient space for string of the same length as +@var{sequence} must be allocated for @var{structure} before calling +@code{fold()}. If @code{fold_constrained} (@pxref{Fold Vars,,Variables}) +is 1, the @var{structure} string is interpreted on input as a list of +constraints for the folding. The characters `` | x < > `` mark bases that +are paired, unpaired, paired upstream, or downstream, respectively; +matching brackets `` ( ) `` denote base pairs, dots ``.'' are used for +unconstrained bases. Constrained folding works by assigning bonus energies +to all structures that comply with the constraint. +@end deftypefun + +@deftypefun float energy_of_struct (char* @var{sequence}, char* @var{structure}) +calculates the energy of @var{sequence} on the @var{structure} +@end deftypefun + +@deftypefun void initialize_fold (int @var{length}) +Obsolete function kept for backward compatibility. +Allocates memory for mfe folding sequences not longer than @var{length}, +and sets up pairing matrix and energy parameters. +@end deftypefun + +@deftypefun void free_arrays () +frees the memory allocated by @code{fold()}. +@end deftypefun + +@deftypefun void update_fold_params () +call this to recalculate the pair matrix and energy parameters after a +change in folding parameters like @code{temperature} +(@pxref{Fold Vars,,Variables}). +@end deftypefun + +Prototypes for these functions are declared in @file{fold.h}. + +@node PF Fold, Inverse Fold, mfe Fold, Folding Routines +@section Partition Function Folding + +Instead of the minimum free energy structure the partition function of +all possible structures and from that the pairing probability for every +possible pair can be calculated, using a dynamic programming algorithm +as described by @cite{McCaskill (1990)}. The following +functions are provided: + +@deftypefun float pf_fold (char* @var{sequence}, char* @var{structure}) +calculates the partition function @math{Z} of @var{sequence} and returns +the free energy of the ensemble @math{F} in kcal/mol, where @math{F=-kT +ln(Z)}. If @var{structure} is not a NULL pointer on input, it contains on +return a string consisting of the letters `` . , | @{ @} ( ) `` denoting +bases that are essentially unpaired, weakly paired, strongly paired without +preference, weakly upstream (downstream) paired, or strongly up- +(down-)stream paired bases, respectively. If @code{fold_constrained} +(@pxref{Fold Vars,,Variables}) is 1, the @var{structure} string is +interpreted on input as a list of constraints for the folding. The +character ``x`` marks bases that must be unpaired, matching brackets `` ( ) +`` denote base pairs, all other characters are ignored. Any pairs +conflicting with the constraint will be forbidden. This usually sufficient +to ensure the constraints are honored. If @code{do_backtrack} (@pxref{Fold +Vars,,Variables}) has been set to 0 base pairing probabilities will not +be computed (saving CPU time), otherwise the @code{pr[iindx[i]-j]} +(@pxref{Fold Vars,,Variables}) will contain the probability that bases i +and j pair. +@end deftypefun + +@deftypefun void init_pf_fold (int @var{length}) +allocates memory for folding sequences not longer than @var{length}; +sets up pairing matrix and energy parameters. Has to be called before +the first call to @code{pf_fold()}. +@end deftypefun + +@deftypefun void free_pf_arrays (void) +frees the memory allocated by @code{init_pf_fold()}. +@end deftypefun + +@deftypefun void update_pf_params (int @var{length}) +Call this function to recalculate the pair matrix and energy parameters +after a change in folding parameters like temperature +(@pxref{Fold Vars,,Variables}). +@end deftypefun + +@deftypefun double mean_bp_dist (int @var{length}) +computes the mean base pair distance in the equilibrium ensemble as a +measure of the structural diversity. It is given by @math{ = +sum_{a,b} p_a * p_b * d(a,b)}, where the sum goes over all pairs of +possible structure @math{a,b}, @math{p_a} is the Boltzmann weight of +structure @math{a}, and @math{d(a,b)} is the base pair distance (see +@code{bp_distance()} in @xref{Distances}.). The mean base pair distances +can be computed efficiently from the pair probabilities @math{p_ij} as +@math{ = sum_{ij} p_ij * (1-p_ij)}. Uses the global @code{pr} array +filled by a previous call to @code{pf_fold()}. +@end deftypefun + +Prototypes for these functions are declared in @file{part_func.h}. + +@node Inverse Fold, Suboptimal folding, PF Fold, Folding Routines +@section Inverse Folding + +We provide two functions that search for sequences with a given +structure, thereby inverting the folding routines. + + +@deftypefun float inverse_fold (char* @var{start}, char* @var{target}) +searches for a sequence with minimum free energy structure +@var{target}, starting with sequence @var{start}. It returns 0 if the +search was successful, otherwise a structure distance to @var{target} +is returned. The found sequence is returned in @var{start}. If @code{give_up} +@vindex give_up +is set to 1, the function will return as soon as it is +clear that the search will be unsuccessful, this speeds up the algorithm +if you are only interested in exact solutions. +Since @code{inverse_fold()} calls @code{fold()} you have to allocate memory +for folding by calling @code{initialize_fold()} +@end deftypefun + +@deftypefun float inverse_pf_fold (char* @var{start}, char* @var{target}) +searches for a sequence with maximum probability to fold into structure +@var{target} using the partition function algorithm. It returns +-kT log(p) where p is the frequency of @var{target} in the ensemble of +possible structures. This is usually much slower than @code{inverse_fold()}. +Since @code{inverse_pf_fold()} calls @code{pf_fold()} you have to allocate +memory for folding by calling @code{init_pf_fold()} +@end deftypefun + +@deftypevar char *symbolset +The global variable @code{char *symbolset} points to the allowed bases, +initially @code{"AUGC"}. It can be used to design sequences from reduced +alphabets. +@end deftypevar + +Prototypes for these functions are declared in @file{inverse.h}. + +@node Suboptimal folding, Cofolding, Inverse Fold, Folding Routines +@section Suboptimal folding + +@deftp {data type} SOLUTION struct @{float energy; char *structure;@} +@end deftp + +@deftypefun SOLUTION* subopt (char* @var{sequence}, char* @var{constraint}, int* @var{delta}, FILE* @var{fp}) +poduces @strong{all} suboptimal secondary structures within +@var{delta}*0.01 kcal/mol of the optimum. The reults are either +directly written to a @var{fp} (if @var{fp} is not @code{NULL}), or +(@var{fp}@code{==NULL}) returned in a @code{SOLUTION *} list terminated +by an entry were the @code{structure} pointer is @code{NULL}. +@end deftypefun + +Prototypes for these functions are declared in @file{subopt.h}. + +@node Cofolding, Local Fold, Suboptimal folding, Folding Routines +@section Predicting hybridization structures of two molecules + +The function of an RNA molecule often depends on its interaction with +other RNAs. The following routines therefore allow to predict structures +formed by two RNA molecules upon hybridization. +One approach to co-folding two RNAs consists of concatenating the two +sequences and keeping track of the concatenation point in all energy +evaluations. Correspondingly, many of the @code{cofold()} and +@code{co_pf_fold()} routines below take one sequence string as argument +and use the the global variable @var{cut_point} to mark the concatenation +point. Note that while the @code{RNAcofold} program uses the '&' character +to mark the chain break in its input, you should not use an '&' when using +the library routines (set @var{cut_point} instead). + +@deftypevar int cut_point +@code{cut_point} marks the position (starting from 1) of the first +nucleotide of the second molecule within the concatenated sequence. +The default value of -1 stands for single molecule folding. The +@code{cut_point} variable is also used by @code{PS_rna_plot()} and +@code{PS_dot_plot()} to mark the chain break in postscript plots. +@end deftypevar + +@deftypefun float cofold (char @var{*sequence}, char @var{*structure}) +The analog to the @code{fold()} function. Computes the minimum free +energy of two RNA molecules interacting. If @code{cut_point==-1} results +should be the same as with @code{fold()}. +@end deftypefun + +@deftypefun void free_co_arrays (void) +Frees arrays allocated by @code{cofold()}. +@end deftypefun + +@c @deftypefun char *tokenize (char @var{*line}) +@c Takes the sequence as it is taken from stdin or a file, sets the +@c @var{cut_point} global variable to the position of the '&' character +@c and cuts out the '&' character to return the sequence as it will be +@c used by all cofold functions. +@c @end deftypefun + +@deftypefun void initialize_cofold (int @var{length}) +Allocates memory for mfe cofolding sequences not longer than @var{length}, +and sets up pairing matrix and energy parameters. +Explicitely calling @code{initialize_cofold()} is normally not necessary, +as it will be called automagically before folding. +@end deftypefun + +@c @deftypefun extern struct plist *get_mfe_plist (struct plist @var{*pl}) +@c This writes the global @var{*pr} array into the new structure +@c @var{plist}, creating an array of the base pairs of the minimum free +@c energy structure (and nothing else). Default probability is 0.95. +@c Used when @var{*pr} is going to be freed or overwritten by other +@c functions (e.g. @code{ co_pf_fold()},@code{cofold()}, etc). +@c @end deftypefun + +Prototypes for these functions are declared in @file{cofold.h}. + + +@section Partition Function Cofolding +As for folding one RNA molecule, this computes the partition function +of all possible structures and the base pair probabilities. Uses the +same global @var{pf_scale} variable to avoid overflows. + +To simplify the implementation the partition function computation is done +internally in a null model that does not include the duplex initiation +energy, i.e. the entropic penalty for producing a dimer from two +monomers). The resulting free energies and pair probabilities are initally +relative to that null model. In a second step the free energies can be +corrected to include the dimerization penalty, and the pair probabilities +can be divided into the conditional pair probabilities given that a re +dimer is formed or not formed. + + +@deftp {data type} cofoldF struct @{double F0AB, FAB, FcAB, FA, FB;@} +@end deftp + +@deftypefun cofoldF co_pf_fold (char* @var{sequence}, char* @var{structure}) +The analog to the @code{pf_fold()} function, it computes the partition +function of two interacting RNA molecules as well as base pair +probabilities. +It returns a struct including free energies computed for different +models. F0AB is the free energy in the null model; FAB is corrected +to include the initiation penalty, FcAB only includes real dimers. FA and +FB are the free energies of the 2 molecules, resp. As with @code{cofold()} +the @var{cut_point} global variable has to be set to mark the chain break +between the molecules. +@end deftypefun + + +@deftypefun void free_co_pf_arrays (void) +frees partition function cofold arrays allocated in @code{ co_pf_fold()}. +@end deftypefun + +@deftypefun void init_co_pf_fold (int @var{length}) +Obsolete function kept for backward compatibility. +Allocates memory for partition function cofolding sequences not longer +than @var{length}, and sets up pairing matrix and energy parameters. +@end deftypefun + +@deftp {data type} plist struct @{int i; int j; float energy;@} +@end deftp + +@deftypefun extern struct plist *get_plist (struct plist @var{*pl}, int @var{length}, double @var{cut_off}) +Makes a list of base pairs out of the global @var{*pr} array, +ignoring all base pairs with a probability less than @var{cut_off}. +This is useful since the @var{pr} array gets overwritten by subsequent +foldings. +@end deftypefun + +Prototypes for these functions are declared in @file{co_part_func.h}. + +@section Cofolding all Dimeres, Concentrations +After computing the partition functions of all possible dimeres one +can compute the probabilities of base pairs, the concentrations out of +start concentrations and sofar and soaway. + +@deftypefun void compute_probabilities (double @var{FAB}, double @var{FEA}, double @var{FEB}, struct plist @var{*prAB}, struct plist @var{*prA}, struct plist @var{*prB}, int @var{Alength}) +Given the pair probabilities and free energies (in the null model) for a +dimer AB and the two constituent monomers A and B, compute the conditional pair +probabilities given that a dimer AB actually forms. +Null model pair probabilities are given as a list as produced by +@code{get_plist()}), the dimer probabilities @var{prAB} are modified in +place. +@end deftypefun + +Dimer formation is inherently concentration dependent. Given the free +energies of the monomers A and B and dimers AB, AA, and BB one can compute +the equilibrium concentrations, given input concentrations of A and B, see +e.g.~@cite{Dimitrov & Zuker (2004)} + +@deftp {data type} ConcEnt struct @{double A0; double B0;double ABc;double AAc; double BBc; double Ac; double Bc;@} +@end deftp + +@deftypefun extern struct ConcEnt *get_concentrations(double @var{FEAB}, double @var{FEAA}, double @var{FEBB}, double @var{FEA}, double @var{FEB}, double * @var{startconc}) +Takes an array @var{startconc} of input concentrations with alternating +entries for the initial concentrations of molecules A and B (terminated by +two zeroes), then computes the resulting equilibrium concentrations +from the free energies for the dimers. Dimer free energies should be the +dimer-only free energies, i.e. the FcAB entries from the @code{cofoldF} struct. +@end deftypefun + +@c @deftypefun int make_probsum (int @var{length}, char @var{*name}) +@c Computes the probability of any base to be paired to a base wtih a +@c number lower than @var{length} (used for e.g. compute probability to +@c be paired within one molecule). +@c @end deftypefun + +Prototypes for these functions are declared in @file{co_part_func.h}. + +@node Local Fold, Alignment Fold, Cofolding, Folding Routines +@section Searching for local mfe structures in large molecules + +Local structures can be predicted by a modified version of the +@code{fold()} algorithm that restricts the span of all base pairs. + +@deftypefun float Lfold (char *@var{string}, char *@var{structure}, int @var{maxdist}) +The local analog to @code{fold()}. Computes the minimum free energy +structure including only base pairs with a span smaller than +@end deftypefun + +@var{maxdist}. + +@deftypefun int pfl_fold (char *@var{sequence}, int @var{winSize}, float @var{cutoff}, struct plist **@var{pl}) +pfl_fold computes partition functions for every window of size +@var{winSize} possible in a RNA molecule, and returns the mean base +pair probabilities in @var{pl}. Note that in contrast to @code{Lfold()}, bases outside +of the window do not influence the structure at all. Only +probabilities higher than @var{cutoff} are kept. +@end deftypefun + +@deftypefun void init_pf_foldLP (int @var{length}) +Analog to @code{init_pf_fold()}. @var{length} is the length of the sequence. +@end deftypefun + +@deftypefun void free_pf_arraysLP (void) +frees the arrays used by @code{pfl_fold()} +@end deftypefun + +@deftypefun void update_pf_paramsLP (int @var{length}) +Analog to @code{update_pf_params()}. @var{length} is the length of the sequence. +@end deftypefun + +@node Alignment Fold, Fold Vars, Local Fold, Folding Routines +@section Predicting Consensus Structures from an Alignment + +Consensus structures can be predicted by a modified version of the +@code{fold()} algorithm that takes a set of aligned sequences instead +of a single sequence. The energy function consists of the mean energy +averaged over the sequences, plus a covariance term that favors pairs +with consistent and compensatory mutations and penalizes pairs that +cannot be formed by all structures. For details see @cite{Hofacker (2002)}. + +@deftypefun float alifold (char** @var{sequences}, char* @var{structure}) +Predicts the consensus structure for the aligned @var{sequences} +and returns the minimum free energy; the mfe structure in bracket +notation (@pxref{notations}) is returned in @var{structure}. +Sufficient space must be allocated for @var{structure} before calling +@code{alifold()}. +@end deftypefun + +@deftypefun void free_alifold_arrays () +frees the memory allocated by @code{alifold()}. +@end deftypefun + +@deftypefun void update_alifold_params () +call this to recalculate the pair matrix and energy parameters after a +change in folding parameters like @code{temperature} +(@pxref{Fold Vars,,Variables}). +@end deftypefun + +@deftypefun float alipf_fold (char** @var{sequences}, char* @var{structure}, pair_info **@var{pi}) +The partition function version of @code{alifold()} works in analogy to +@code{pf_fold()}. Pair probabilities and information about sequence +covariations are returned via the @var{pi} variable as a list of +@code{pair_info} structs. The list is terminated by the first entry with +@code{pi.i = 0}. +@end deftypefun + +@deftp {data type} pair_info struct @{short i,j; float p; float ent; short bp[8]; char comp;@} +for each base pair @code{i,j} the structure lists: its probability +@code{p}, an entropy-like measure for its well-definedness @code{ent}, +and in @code{bp[]} the frequency of each type of pair. @code{bp[0]} +contains the number of non-compatible sequences, @code{bp[1]} the +number of CG pairs, etc. +@end deftp + +@deftypevar double cv_fact +@code{cv_fact} controls the weight of the covariance term in the +energy function. Default is 1. +@end deftypevar + +@deftypevar double nc_fact +controls the magnitude of the penalty for non-compatible sequences in +the covariance term. Default is 1. +@end deftypevar + +@node Fold Vars, Param Files , Alignment Fold, Folding Routines +@section Global Variables for the Folding Routines + +The following global variables change the behavior the folding +algorithms or contain additional information after folding. + +@deftypevar int noGU +do not allow GU pairs if equal 1; default is 0. +@end deftypevar + +@deftypevar int no_closingGU +if 1 allow GU pairs only inside stacks, not as closing pairs; +default is 0. +@end deftypevar + +@deftypevar int noLonelyPairs +Disallow all pairs which can @strong{only} occur as lonely pairs (i.e. as helix +of length 1). This avoids lonely base pairs in the predicted structures in +most cases. +@end deftypevar + +@deftypevar int tetra_loop +include special stabilizing energies for some tetra loops; default is 1. +@end deftypevar + +@deftypevar int energy_set +if 1 or 2: fold sequences from an artificial alphabet ABCD..., where A +pairs B, C pairs D, etc. using either GC (1) or AU parameters (2); +default is 0, you probably don't want to change it. +@end deftypevar + +@deftypevar float temperature +rescale energy parameters to a temperature of @code{temperature} C. +Default is 37C. You have to call the update_@dots{}_params() functions after +changing this parameter. +@end deftypevar + +@deftypevar int dangles +if set to 0 no stabilizing energies are assigned to bases adjacent to +helices in free ends and multiloops (so called dangling ends). Normally +(@code{dangles = 1}) dangling end energies are assigned only to unpaired +bases and a base cannot participate simultaneously in two dangling ends. In +the partition function algorithm @code{pf_fold()} these checks are neglected. +If @code{dangles} is set to 2, the @code{fold()} and +@code{energy_of_struct()} function will also follow this convention. This +treatment of dangling ends gives more favorable energies to helices +directly adjacent to one another, which can be beneficial since such +helices often do engage in stabilizing interactions through co-axial +stacking.@* +If @code{dangles = 3} co-axial stacking is explicitly included for +adjacent helices in mutli-loops. The option affects only mfe folding +and energy evaluation (@code{fold()} and @code{energy_of_struct()}), as +well as suboptimal folding (@code{subopt()}) via re-evaluation of energies. +Co-axial stacking with one intervening mismatch is not considered so far. + +Default is 1, @code{pf_fold()} treats 1 as 2. +@end deftypevar + +@deftypevar char* nonstandards +Lists additional base pairs that will be allowed to form in addition to +GC, CG, AU, UA, GU and UG. Nonstandard base pairs are given a stacking +energy of 0. +@end deftypevar + +@deftypevar int cut_point +To evaluate the energy of a duplex structure (a structure formed by two +strands), concatenate the to sequences and set @var{cut_point} to the +first base of the second strand in the concatenated sequence. Reset to +0 or -1 (the default) to evaluate normal single sequence structures. +@end deftypevar + +@deftypevar {struct bond @{ int i,j;@}} base_pair +Contains a list of base pairs after a call to @code{fold()}. +@code{base_pair[0].i} contains the total number of pairs. +@end deftypevar + +@deftypevar double* pr +contains the base pair probability matrix after a call to @code{pf_fold()}. +@end deftypevar + +@deftypevar int* iindx +index array to move through pr. The probability for base i and j to form +a pair is in @code{pr[iindx[i]-j]}. +@end deftypevar + +@deftypevar float pf_scale +a scaling factor used by @code{pf_fold()} to avoid overflows. Should be set +to approximately exp@math{((-F/kT)/length)}, where @math{F} is an estimate +for the ensemble free energy, for example the minimum free energy. You must +call @code{update_pf_params()} or @code{init_pf_fold()} after changing this +parameter. If pf_scale is -1 (the default) , an estimate will be provided +automatically when calling @code{init_pf_fold()} or +@code{update_f_params()}. The automatic estimate is usually insufficient +for sequences more than a few hundred bases long. +@end deftypevar + +@deftypevar int fold_constrained +If 1, calculate constrained minimum free energy structures. @xref{mfe Fold}, +for more information. Default is 0; +@end deftypevar + +@deftypevar int do_backtrack +if 0, do not calculate pair probabilities in @code{pf_fold()}; this is about +twice as fast. Default is 1. +@end deftypevar + +@deftypevar char backtrack_type +only for use by @code{inverse_fold()}; 'C': force (1,N) to be paired, +'M' fold as if the sequence were inside a multi-loop. Otherwise the +usual mfe structure is computed. +@end deftypevar + +include @file{fold_vars.h} if you want to change any of these variables +from their defaults. + +@node Param Files, , Fold Vars, Folding Routines +@section Energy Parameter Files + +A default set of parameters, identical to the one described in @cite{Mathews +et.al. (1999)}, is compiled into the library. +Alternately, parameters can be read from and written to a file. + +@deftypefun void read_parameter_file (const char @var{fname}[]) +reads energy parameters from file @var{fname}. See below for the format of +the parameter file. +@end deftypefun +@deftypefun void write_parameter_file (const char @var{fname}[]) +writes current energy parameters to the file @var{fname}. +@end deftypefun + +The following describes the file format expected by +@code{read_parameter_file()}. All energies should be given as integers in +units of 0.01kcal/mol. + +Various loop parameters depend in general on the pairs closing the loops, +as well as unpaired bases in the loops. Internally, the library +distinguishes 8 types of pairs (CG=1, GC=2, GU=3, UG=4, AU=5, UA=6, +nonstandard=7, 0= no pair), and 5 types of bases (A=1, C=2, G=3, U=4 and 0 +for anything else). Parameters belonging to pairs of type 0 are not listed +in the parameter files, but values for nonstandard pairs (type 7) and +nonstandard bases (type 0) are. Thus, a table for symmetric size 2 interior +loops would have 7*7*5*5 entries (2 pairs, two unpaired bases). + +The order of entries always uses the closing pair or pairs as the first +indices followed by the unpaired bases in 5' to 3' direction. To determine +the type of a pair consider the base at the (local) 5' end of each strand +first, i.e. use the pairs @math{(i,j)} and @math{(q,p)} for an interior +loop with @math{i +#include +#include "utils.h" +#include "fold_vars.h" +#include "fold.h" +#include "part_func.h" +#include "inverse.h" +#include "RNAstruct.h" +#include "treedist.h" +#include "stringdist.h" +#include "profiledist.h" + +void main() +@{ + char *seq1="CGCAGGGAUACCCGCG", *seq2="GCGCCCAUAGGGACGC", + *struct1,* struct2,* xstruc; + float e1, e2, tree_dist, string_dist, profile_dist, kT; + Tree *T1, *T2; + swString *S1, *S2; + float **pf1, **pf2; + + /* fold at 30C instead of the default 37C */ + temperature = 30.; /* must be set *before* initializing */ + /* allocate memory for fold(), could be skipped */ + initialize_fold(strlen(seq1)); + + /* allocate memory for structure and fold */ + struct1 = (char* ) space(sizeof(char)*(strlen(seq1)+1)); + e1 = fold(seq1, struct1); + + struct2 = (char* ) space(sizeof(char)*(strlen(seq2)+1)); + e2 = fold(seq2, struct2); + + free_arrays(); /* free arrays used in fold() */ + + /* produce tree and string representations for comparison */ + xstruc = expand_Full(struct1); + T1 = make_tree(xstruc); + S1 = Make_swString(xstruc); + free(xstruc); + + xstruc = expand_Full(struct2); + T2 = make_tree(xstruc); + S2 = Make_swString(xstruc); + free(xstruc); + + /* calculate tree edit distance and aligned structures with gaps */ + edit_backtrack = 1; + tree_dist = tree_edit_distance(T1, T2); + free_tree(T1); free_tree(T2); + unexpand_aligned_F(aligned_line); + printf("%s\n%s %3.2f\n", aligned_line[0], aligned_line[1], tree_dist); + + /* same thing using string edit (alignment) distance */ + string_dist = string_edit_distance(S1, S2); + free(S1); free(S2); + printf("%s mfe=%5.2f\n%s mfe=%5.2f dist=%3.2f\n", + aligned_line[0], e1, aligned_line[1], e2, string_dist); + + /* for longer sequences one should also set a scaling factor for + partition function folding, e.g: */ + kT = (temperature+273.15)*1.98717/1000.; /* kT in kcal/mol */ + pf_scale = exp(-e1/kT/strlen(seq1)); + init_pf_fold(strlen(seq1)); + + /* calculate partition function and base pair probabilities */ + e1 = pf_fold(seq1, struct1); + pf1 = Make_bp_profile(strlen(seq1)); + + e2 = pf_fold(seq2, struct2); + pf2 = Make_bp_profile(strlen(seq2)); + + free_pf_arrays(); /* free space allocated for pf_fold() */ + + profile_dist = profile_edit_distance(pf1, pf2); + printf("%s free energy=%5.2f\n%s free energy=%5.2f dist=%3.2f\n", + aligned_line[0], e1, aligned_line[1], e2, profile_dist); + + free_profile(pf1); free_profile(pf2); +@} +@end example + +In a typical Unix environment you would compile this program using: +@kbd{cc -c example.c -I@var{hpath}} +and link using +@kbd{cc -o example -L@var{lpath} -lRNA -lm} +where @var{hpath} and @var{lpath} point to the location of the header +files and library, respectively. + +@node References, Function Index, Example, Top +@chapter References + +@itemize - +@item D.H. Mathews, J. Sabina, M. Zucker and H. Turner (1999)@* + Expanded sequence dependence of thermodynamic parameters provides + robust prediction of RNA secondary structure, JMB, 288: 911-940 + +@item M. Zuker and P. Stiegler (1981)@* + Optimal computer folding of large RNA sequences using + thermodynamic and auxiliary information, Nucl Acid Res 9: 133-148 + +@item D.A. Dimitrov, M.Zuker(2004)@* + Prediction of hybridization and melting for double stranded nucleic + acids, Biophysical J. 87: 215-226, + +@item J.S. McCaskill (1990)@* + The equilibrium partition function and base pair binding + probabilities for RNA secondary structures, Biopolymers 29: 1105-1119 + +@item D.H. Turner, N. Sugimoto and S.M. Freier (1988)@* + RNA structure prediction, Ann Rev Biophys Biophys Chem 17: 167-192 + +@item J.A. Jaeger, D.H. Turner and M. Zuker (1989)@* + Improved predictions of secondary structures for RNA, + Proc. Natl. Acad. Sci. 86: 7706-7710 + +@item L. He, R. Kierzek, J. SantaLucia, A.E. Walter and D.H. Turner (1991)@* + Nearest-Neighbor Parameters For GU Mismatches, + Biochemistry 30: 11124-11132 + +@item A.E. Peritz, R. Kierzek, N, Sugimoto, D.H. Turner (1991)@* + Thermodynamic Study of Internal Loops in Oligoribonucleotides ... , + Biochemistry 30: 6428--6435 + +@item A. Walter, D. Turner, J. Kim, M. Lyttle, P. M@"uller, D. Mathews and M. Zuker (1994)@* + Coaxial stacking of helices enhances binding of Oligoribonucleotides.., + Proc. Natl. Acad. Sci. 91: 9218-9222 + +@item B.A. Shapiro, (1988)@* + An algorithm for comparing multiple RNA secondary structures, + CABIOS 4, 381-393 + +@item B.A. Shapiro and K. Zhang (1990)@* + Comparing multiple RNA secondary structures using tree comparison, + CABIOS 6, 309-318 + +@item R. Bruccoleri and G. Heinrich (1988)@* + An improved algorithm for nucleic acid secondary structure display, + CABIOS 4, 167-173 + +@item W. Fontana , D.A.M. Konings, P.F. Stadler, P. Schuster (1993) @* + Statistics of RNA secondary structures, Biopolymers 33, 1389-1404 + +@item W. Fontana, P.F. Stadler, E.G. Bornberg-Bauer, T. Griesmacher, I.L. + Hofacker, M. Tacker, P. Tarazona, E.D. Weinberger, P. Schuster (1993)@* + RNA folding and combinatory landscapes, Phys. Rev. E 47: 2083-2099 + +@item I.L. Hofacker, W. Fontana, P.F. Stadler, S. Bonhoeffer, M. Tacker, P. + Schuster (1994) Fast Folding and Comparison of RNA Secondary Structures. + Monatshefte f. Chemie 125: 167-188 + +@item I.L. Hofacker (1994) The Rules of the Evolutionary Game for RNA: + A Statistical Characterization of the Sequence to Structure Mapping in RNA. + PhD Thesis, University of Vienna. + +@item I.L. Hofacker, M. Fekete, P.F. Stadler (2002). + Secondary Structure Prediction for Aligned RNA Sequences. + J. Mol. Biol. 319:1059-1066 + +@item D. Adams (1979) @* + The hitchhiker's guide to the galaxy, Pan Books, London +@end itemize + +@node Function Index, Variable Index, References, Top + +@unnumbered Function Index +@printindex fn + +@node Variable Index, , Function Index, Top + +@unnumbered Variable Index +@printindex vr + +@contents +@bye + +@c LocalWords: texinfo setfilename RNAlib settitle syncodeindex vr fn iftex +@c LocalWords: afourpaper ifinfo setchapternewpage titlepage sp vskip pt dir +@c LocalWords: filll mfe PF Params Zuker Stiegler pxref Freier al findex mol +@c LocalWords: struct int params McCaskill pf pr iindx init func kT +@c LocalWords: vindex symbolset noGU GU closingGU tetra ABCD AU rescale UA CG +@c LocalWords: multiloops nonstandards UG GAAG GA AG exp xref vars Shapiro's +@c LocalWords: homeomorphically UU HH emph un unexpand unweight RNAstruct INF +@c LocalWords: xstruc treedist swString stringdist bp profiledist PS rna Fri +@c LocalWords: nrerror stderr congruential xsubi fp utils dist seq RNAfold CA +@c LocalWords: CGCAGGGAUACCCGCG GCGCCCAUAGGGACGC initialising strlen sizeof +@c LocalWords: printf Nucl Biopolymers Sugimoto Biophys Chem Proc Natl Sci CU +@c LocalWords: Kierzek SantaLucia CABIOS Zhang Konings Bornberg RNAdistance +@c LocalWords: Griesmacher Tarazona Weinberger Phys Monatshefte enthalpies cu +@c LocalWords: Chemie hitchhiker's printindex ci cc Tetraloops tetraloops url +@c LocalWords: GAAA html http www tbi univie ac ivo Param deftypefun var ln +@c LocalWords: deftypevar const fname samp erand kbd hpath lpath lRNA lm Acad +@c LocalWords: Peritz Oligoribonucleotides Lyttle uller Bonhoeffer ifclear lt +@c LocalWords: smallexample texi ifset ifhtml href ViennaRNA mailto gt noLP +@c LocalWords: initially co noindent gmlRNA gml naview Bruccoleri struc AUGC +@c LocalWords: strcmp LocalWords Hofacker Stadler noLonelyPairs GC mutli GAUA +@c LocalWords: CGCU CUU GCA GCCA termAU PostScript Zucker JMB combinatory pre diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1 new file mode 100755 index 00000000..45bb9b6b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1 @@ -0,0 +1,67 @@ +.\" .ER +.TH "RNAPDIST" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNApdist \- calculate distances between thermodynamic RNA secondary +structures ensembles +.SH "SYNOPSIS" +\fBRNApdist [\-Xp|m|f|c] [\-B\ [file]] [\-T\ temp] [\-4] [\-d] [\-noGU] [\-noCloseGU] [\-e\ e_set] [\-P\ paramfile] [\-nsp\ pairs] + +.SH "DESCRIPTION" +.I RNApdist +reads RNA sequences from stdin and calculates structure distances between +the thermodynamic ensembles of their secondary structures. +To do this the partition function and matrix of base pairing probabilities is +computed for each sequence. The probability matrix is then condensed into a +vector holding for each base the probabilities of being unpaired, paired +upstream, or paired downstream, respectively. These profiles are compared +by a standard alignment algorithm. + +The base pair probabilities are also saved as postscript "dot plots" (as in +RNAfold) in the files "name_dp.ps", where name is the name of the sequence, +or a number if unnamed. + +.SH "OPTIONS" +.IP \fB\-Xp\fP +compare the structures pairwise (p), that is first with 2nd, third +with 4th etc. This is the default. +.IP \fB\-Xm\fP +calculate the distance matrix between all structures. The output is +formatted as a lower triangle matrix. +.IP \fB\-Xf\fP +compare each structure to the first one. +.IP \fB\-Xc\fP +compare continuously, that is i\-th with (i+1)th structure. +.IP \fB\-B\ [\fI\fP] +Print an "alignment" with gaps of the profiles, using the following symbols: +.br +( ) essentially upstream (downstream) paired bases +.br +{ } weakly upstream (downstream) paired bases +.br + | strongly paired bases without preference +.br + , weakly paired bases without preference +.br + . essentially unpaired bases. +.br + +The aligned structures are written to \fI\fP, if specified. Otherwise +output is written to stdout, unless the \-Xm option is set in which case +"backtrack.file" is used. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. + +.SH "REFERENCES" +Bonhoeffer S, McCaskill J S, Stadler P F, Schuster P, (1993) +RNA multi\-structure landscapes, Euro Biophys J:22,13\-24 +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Peter F Stadler, Ivo L Hofacker, Sebastian Bonhoeffer. +.SH "BUGS" +We hoped you wouldn't find them. +.br +Comments should be sent to rna@tbi.univie.ac.at + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1.in new file mode 100755 index 00000000..24b88a42 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNApdist.1.in @@ -0,0 +1,67 @@ +.\" .ER +.TH "RNAPDIST" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNApdist \- calculate distances between thermodynamic RNA secondary +structures ensembles +.SH "SYNOPSIS" +\fBRNApdist [\-Xp|m|f|c] [\-B\ [file]] [\-T\ temp] [\-4] [\-d] [\-noGU] [\-noCloseGU] [\-e\ e_set] [\-P\ paramfile] [\-nsp\ pairs] + +.SH "DESCRIPTION" +.I RNApdist +reads RNA sequences from stdin and calculates structure distances between +the thermodynamic ensembles of their secondary structures. +To do this the partition function and matrix of base pairing probabilities is +computed for each sequence. The probability matrix is then condensed into a +vector holding for each base the probabilities of being unpaired, paired +upstream, or paired downstream, respectively. These profiles are compared +by a standard alignment algorithm. + +The base pair probabilities are also saved as postscript "dot plots" (as in +RNAfold) in the files "name_dp.ps", where name is the name of the sequence, +or a number if unnamed. + +.SH "OPTIONS" +.IP \fB\-Xp\fP +compare the structures pairwise (p), that is first with 2nd, third +with 4th etc. This is the default. +.IP \fB\-Xm\fP +calculate the distance matrix between all structures. The output is +formatted as a lower triangle matrix. +.IP \fB\-Xf\fP +compare each structure to the first one. +.IP \fB\-Xc\fP +compare continuously, that is i\-th with (i+1)th structure. +.IP \fB\-B\ [\fI\fP] +Print an "alignment" with gaps of the profiles, using the following symbols: +.br +( ) essentially upstream (downstream) paired bases +.br +{ } weakly upstream (downstream) paired bases +.br + | strongly paired bases without preference +.br + , weakly paired bases without preference +.br + . essentially unpaired bases. +.br + +The aligned structures are written to \fI\fP, if specified. Otherwise +output is written to stdout, unless the \-Xm option is set in which case +"backtrack.file" is used. +.PP +The \fB\-T\fP, \fB\-d\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. + +.SH "REFERENCES" +Bonhoeffer S, McCaskill J S, Stadler P F, Schuster P, (1993) +RNA multi\-structure landscapes, Euro Biophys J:22,13\-24 +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHORS" +Peter F Stadler, Ivo L Hofacker, Sebastian Bonhoeffer. +.SH "BUGS" +We hoped you wouldn't find them. +.br +Comments should be sent to rna@tbi.univie.ac.at + + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1 new file mode 100755 index 00000000..eea198a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1 @@ -0,0 +1,46 @@ +.\" .ER +.TH "RNAPLFOLD" "l" "1.6" "Stephan Bernhart" "ViennaRNA" +.SH "NAME" +RNAplfold \- calculate locally stable secondary structure - pair probabilities +.SH "SYNOPSIS" +\fBRNAplfold\fP [\-L span] [\-T\ \fItemp\fP] [\-4] [\-noLP] [\-noGU] +[\-noCloseGU] [\-P\ \fIparamfile\fP] [\-nsp\ \fIpairs\fP] +[\-d[0|2] [\-c \fIcutoff\fP] + +.SH "DESCRIPTION" +.I RNAplfold +computes local pair probabilities for base pairs with a maximal span +of L. The probabilities are averaged over all windows of size L that +contain the base pair. For a sequence of length n and a window size of L the +algorithm uses only O(n+L*L) memory and O(n*L*L) CPU time. Thus it is +practical to "scan" very large genomes for short stable RNA structures. + +Output consists of a dot plot in postscript file, where the averaged pair probabilities +can easily be parsed and visually inspected. + +.SH "OPTIONS" +.TP +.B \-L span +Set the window Size to span. I.e. no +pairs (i,j) with j\-i>span will be allowed. default = 70 +.PP +.B \-c cutoff +Report only base pairs with an average probability > cutoff default=0.01. +.PP +The \fB\-T\fP, \fB\-d\fP \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in +RNAfold. + +.SH "SEE ALSO" +RNALfold(1) + +.SH "REFERENCES" +S. H. Bernhart, I.L. Hofacker, and P.F. Stadler +"Local Base Pairing Probabilities in Large RNAs" +Bioinformatics (2006) in press +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Stephan H Bernhart, Ivo L Hofacker, Peter F Stadler. +.br +Send comments to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1.in new file mode 100755 index 00000000..eea198a4 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplfold.1.in @@ -0,0 +1,46 @@ +.\" .ER +.TH "RNAPLFOLD" "l" "1.6" "Stephan Bernhart" "ViennaRNA" +.SH "NAME" +RNAplfold \- calculate locally stable secondary structure - pair probabilities +.SH "SYNOPSIS" +\fBRNAplfold\fP [\-L span] [\-T\ \fItemp\fP] [\-4] [\-noLP] [\-noGU] +[\-noCloseGU] [\-P\ \fIparamfile\fP] [\-nsp\ \fIpairs\fP] +[\-d[0|2] [\-c \fIcutoff\fP] + +.SH "DESCRIPTION" +.I RNAplfold +computes local pair probabilities for base pairs with a maximal span +of L. The probabilities are averaged over all windows of size L that +contain the base pair. For a sequence of length n and a window size of L the +algorithm uses only O(n+L*L) memory and O(n*L*L) CPU time. Thus it is +practical to "scan" very large genomes for short stable RNA structures. + +Output consists of a dot plot in postscript file, where the averaged pair probabilities +can easily be parsed and visually inspected. + +.SH "OPTIONS" +.TP +.B \-L span +Set the window Size to span. I.e. no +pairs (i,j) with j\-i>span will be allowed. default = 70 +.PP +.B \-c cutoff +Report only base pairs with an average probability > cutoff default=0.01. +.PP +The \fB\-T\fP, \fB\-d\fP \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-e\fP, \fB\-P\fP, \fB\-nsp\fP, options work as in +RNAfold. + +.SH "SEE ALSO" +RNALfold(1) + +.SH "REFERENCES" +S. H. Bernhart, I.L. Hofacker, and P.F. Stadler +"Local Base Pairing Probabilities in Large RNAs" +Bioinformatics (2006) in press +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHORS" +Stephan H Bernhart, Ivo L Hofacker, Peter F Stadler. +.br +Send comments to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1 new file mode 100755 index 00000000..aafeb070 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1 @@ -0,0 +1,47 @@ +.\" .ER +.TH "RNAPLOT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAplot \- Draw RNA Secondary Structures +.SH "SYNOPSIS" +\fBRNAplot [\-t\ \fI0|1\fP] [\-o\ \fIps|gml|xrna|svg\fP] +[\-\-pre\ \fIstring\fP] [\-\-post \fIstring\fP] + +.SH "DESCRIPTION" +.I RNAplot +reads RNA sequences and structures from stdin in the format as produced by +RNAfold and produces drawings of the secondary structure graph. +The coordinates are produced using either E. Bruccoleri's naview routines, +or a simple radial layout method. + +If the sequence was preceded by a line of the form +.br +> name +.br +the output file will be named "name_ss.ps" otherwise "rna.ps" is used. +Existing files of the same name will be overwritten. + + +.SH "OPTIONS" +.TP +.B \-t\ \fI0|1\fP +Choose the layout algorithm. Simple radial layout if 0, or naview if 1. +Default is 1. +.TP +.B \-o\ \fIps|gml|xrna|svg\fP +Specify output format. Available formats are: PostScript (ps), Graph +Meta Language (gml), Scalable Vector Graphics (svg), and XRNA save file +(xrna). Output filenames will end in ".ps" ".gml" ".svg" ".ss", +respectively. Default is ps. +.TP +.B \-\-pre \fIstring\fP \-\-post \fIstring\fP +Add annotation macros to postscript file, and add the postscript code +in "string" just before (\-\-pre) or after (\-\-post) the code to draw the +structure. This is an easy way to add annotation, e.g to mark position +15 with circle use \-\-post "15 cmark" + +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. +.SH "AUTHOR" +Ivo L Hofacker +.br +Send comments and bug reports to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1.in new file mode 100755 index 00000000..7a5d02ff --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAplot.1.in @@ -0,0 +1,47 @@ +.\" .ER +.TH "RNAPLOT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAplot \- Draw RNA Secondary Structures +.SH "SYNOPSIS" +\fBRNAplot [\-t\ \fI0|1\fP] [\-o\ \fIps|gml|xrna|svg\fP] +[\-\-pre\ \fIstring\fP] [\-\-post \fIstring\fP] + +.SH "DESCRIPTION" +.I RNAplot +reads RNA sequences and structures from stdin in the format as produced by +RNAfold and produces drawings of the secondary structure graph. +The coordinates are produced using either E. Bruccoleri's naview routines, +or a simple radial layout method. + +If the sequence was preceded by a line of the form +.br +> name +.br +the output file will be named "name_ss.ps" otherwise "rna.ps" is used. +Existing files of the same name will be overwritten. + + +.SH "OPTIONS" +.TP +.B \-t\ \fI0|1\fP +Choose the layout algorithm. Simple radial layout if 0, or naview if 1. +Default is 1. +.TP +.B \-o\ \fIps|gml|xrna|svg\fP +Specify output format. Available formats are: PostScript (ps), Graph +Meta Language (gml), Scalable Vector Graphics (svg), and XRNA save file +(xrna). Output filenames will end in ".ps" ".gml" ".svg" ".ss", +respectively. Default is ps. +.TP +.B \-\-pre \fIstring\fP \-\-post \fIstring\fP +Add annotation macros to postscript file, and add the postscript code +in "string" just before (\-\-pre) or after (\-\-post) the code to draw the +structure. This is an easy way to add annotation, e.g to mark position +15 with circle use \-\-post "15 cmark" + +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. +.SH "AUTHOR" +Ivo L Hofacker +.br +Send comments and bug reports to diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1 new file mode 100755 index 00000000..3cccb2b0 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1 @@ -0,0 +1,78 @@ +.\" .ER +.TH "RNASUBOPT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAsubopt \- calculate suboptimal secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNAsubopt [\-e\ \fIrange\fP] [\-ep \fIprange\fP] [\-s] [\-p\ \fIn\fP] [\-T\ \fItemp\fP] [\-d[0|1|2|3]] [\-4] [\-noGU] [\-noCloseGU] [\-P\ paramfile] [\-logML] [\-nsp\ pairs] + +.SH "DESCRIPTION" +.I RNAsubopt +reads RNA sequences from stdin and calculates all suboptimal secondary +structures within a user defined energy range above the minimum free +energy (mfe). It prints the suboptimal structures in bracket notation +followed by the energy in kcal/mol to stdout. +Be careful, the number of structures returned grows exponentially with both +sequence length and energy range. +.SH "OPTIONS" +.TP +.B \-e\ \fIrange\fP +Calculate suboptimal structures within \fIrange\fP kcal/mol of the mfe. +Default is 1. +.TP +.B \-s +Sort the structures by energy. Since the sort in is done in memory, +this becomes impractical when the number of structures produced goes +into millions. In such cases better pipe the output through `sort +1n'. +.TP +.B \-p \fIn\fP +Instead of producing all suboptimals in a range, produce a random sample +of \fIn\fP suboptimal structures, drawn with probabilities equal to +their Boltzmann weights via stochastic backtracking in the partition +function. +.TP +.B \-d[0|1|2|3] +Change treatment of dangling ends, as in RNAfold and RNAeval. The +default is \-d2 (as in partition function folding). If \-d1 or \-d3 are +specified the structures are generated as with \-d2 but energies are +re\-evaluated before printing. +.TP +.B \-logML +re\-calculate energies of structures using a logarithmic energy function for +multi\-loops before output. This option does not effect structure +generation, only the energies that is printed out. Since logML lowers +energies somewhat, some structures may be missing. +.TP +.B \-ep \fIprange\fP +Only print structures with energy within \fIprange\fR of the mfe. Useful in +conjunction with \-logML, \-d1 or \-d3: while the \-e option specifies the +range before energies are re\-evaluated, \-ep specifies the maximum energy +after re\-evaluation. +.TP +.B \-noLP +Only produce structures without lonely pairs (helices of length 1). This +reduces the number of structures drastically and should therefore be used +for longer sequences and larger energy ranges. +.PP +The \fB\-T\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. + + +.SH "REFERENCES" +Please cite: +.br +S. Wuchty, W. Fontana, I. L. Hofacker and P. Schuster +"Complete Suboptimal Folding of RNA and the Stability of +Secondary Structures", +Biopolymers, 49, 145\-165 (1999) + +.SH "VERSION" +This man page documents version 1.6 Vienna RNA Package. + +.SH "AUTHORS" +Ivo L Hofacker, Stefan Wuchty, Walter Fontana. +.br +Send comments and bug reports to +\" LocalWords: RNASUBOPT RNAsubopt suboptimal RNAs fBRNAsubopt fIrange fP ep +\" LocalWords: prange lodos fItemp noGU noCloseGU paramfile logML nsp stdin +\" LocalWords: mfe kcal mol stdout TP RNAfold RNAeval multi fIprange noLP fB +\" LocalWords: br Wuchty Fontana Hofacker Schuster Biopolymers Ivo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1.in b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1.in new file mode 100755 index 00000000..89e34370 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/RNAsubopt.1.in @@ -0,0 +1,78 @@ +.\" .ER +.TH "RNASUBOPT" "l" "" "Ivo Hofacker" "Vienna RNA" +.SH "NAME" +RNAsubopt \- calculate suboptimal secondary structures of RNAs +.SH "SYNOPSIS" +\fBRNAsubopt [\-e\ \fIrange\fP] [\-ep \fIprange\fP] [\-s] [\-p\ \fIn\fP] [\-T\ \fItemp\fP] [\-d[0|1|2|3]] [\-4] [\-noGU] [\-noCloseGU] [\-P\ paramfile] [\-logML] [\-nsp\ pairs] + +.SH "DESCRIPTION" +.I RNAsubopt +reads RNA sequences from stdin and calculates all suboptimal secondary +structures within a user defined energy range above the minimum free +energy (mfe). It prints the suboptimal structures in bracket notation +followed by the energy in kcal/mol to stdout. +Be careful, the number of structures returned grows exponentially with both +sequence length and energy range. +.SH "OPTIONS" +.TP +.B \-e\ \fIrange\fP +Calculate suboptimal structures within \fIrange\fP kcal/mol of the mfe. +Default is 1. +.TP +.B \-s +Sort the structures by energy. Since the sort in is done in memory, +this becomes impractical when the number of structures produced goes +into millions. In such cases better pipe the output through `sort +1n'. +.TP +.B \-p \fIn\fP +Instead of producing all suboptimals in a range, produce a random sample +of \fIn\fP suboptimal structures, drawn with probabilities equal to +their Boltzmann weights via stochastic backtracking in the partition +function. +.TP +.B \-d[0|1|2|3] +Change treatment of dangling ends, as in RNAfold and RNAeval. The +default is \-d2 (as in partition function folding). If \-d1 or \-d3 are +specified the structures are generated as with \-d2 but energies are +re\-evaluated before printing. +.TP +.B \-logML +re\-calculate energies of structures using a logarithmic energy function for +multi\-loops before output. This option does not effect structure +generation, only the energies that is printed out. Since logML lowers +energies somewhat, some structures may be missing. +.TP +.B \-ep \fIprange\fP +Only print structures with energy within \fIprange\fR of the mfe. Useful in +conjunction with \-logML, \-d1 or \-d3: while the \-e option specifies the +range before energies are re\-evaluated, \-ep specifies the maximum energy +after re\-evaluation. +.TP +.B \-noLP +Only produce structures without lonely pairs (helices of length 1). This +reduces the number of structures drastically and should therefore be used +for longer sequences and larger energy ranges. +.PP +The \fB\-T\fP, \fB\-4\fP, \fB\-noGU\fP, \fB\-noCloseGU\fP, +\fB\-P\fP, \fB\-nsp\fP, options work as in RNAfold. + + +.SH "REFERENCES" +Please cite: +.br +S. Wuchty, W. Fontana, I. L. Hofacker and P. Schuster +"Complete Suboptimal Folding of RNA and the Stability of +Secondary Structures", +Biopolymers, 49, 145\-165 (1999) + +.SH "VERSION" +This man page documents version @VERSION@ Vienna RNA Package. + +.SH "AUTHORS" +Ivo L Hofacker, Stefan Wuchty, Walter Fontana. +.br +Send comments and bug reports to +\" LocalWords: RNASUBOPT RNAsubopt suboptimal RNAs fBRNAsubopt fIrange fP ep +\" LocalWords: prange lodos fItemp noGU noCloseGU paramfile logML nsp stdin +\" LocalWords: mfe kcal mol stdout TP RNAfold RNAeval multi fIprange noLP fB +\" LocalWords: br Wuchty Fontana Hofacker Schuster Biopolymers Ivo diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/texinfo.tex b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/texinfo.tex new file mode 100755 index 00000000..58bea4dd --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/man/texinfo.tex @@ -0,0 +1,7086 @@ +% texinfo.tex -- TeX macros to handle Texinfo files. +% +% Load plain if necessary, i.e., if running under initex. +\expandafter\ifx\csname fmtname\endcsname\relax\input plain\fi +% +\def\texinfoversion{2005-01-30.17} +% +% Copyright (C) 1985, 1986, 1988, 1990, 1991, 1992, 1993, 1994, 1995, +% 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005 Free Software +% Foundation, Inc. +% +% This texinfo.tex file is free software; you can redistribute it and/or +% modify it under the terms of the GNU General Public License as +% published by the Free Software Foundation; either version 2, or (at +% your option) any later version. +% +% This texinfo.tex file is distributed in the hope that it will be +% useful, but WITHOUT ANY WARRANTY; without even the implied warranty +% of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU +% General Public License for more details. +% +% You should have received a copy of the GNU General Public License +% along with this texinfo.tex file; see the file COPYING. If not, write +% to the Free Software Foundation, Inc., 59 Temple Place - Suite 330, +% Boston, MA 02111-1307, USA. +% +% As a special exception, when this file is read by TeX when processing +% a Texinfo source document, you may use the result without +% restriction. (This has been our intent since Texinfo was invented.) +% +% Please try the latest version of texinfo.tex before submitting bug +% reports; you can get the latest version from: +% http://www.gnu.org/software/texinfo/ (the Texinfo home page), or +% ftp://tug.org/tex/texinfo.tex +% (and all CTAN mirrors, see http://www.ctan.org). +% The texinfo.tex in any given distribution could well be out +% of date, so if that's what you're using, please check. +% +% Send bug reports to bug-texinfo@gnu.org. Please include including a +% complete document in each bug report with which we can reproduce the +% problem. Patches are, of course, greatly appreciated. +% +% To process a Texinfo manual with TeX, it's most reliable to use the +% texi2dvi shell script that comes with the distribution. For a simple +% manual foo.texi, however, you can get away with this: +% tex foo.texi +% texindex foo.?? +% tex foo.texi +% tex foo.texi +% dvips foo.dvi -o # or whatever; this makes foo.ps. +% The extra TeX runs get the cross-reference information correct. +% Sometimes one run after texindex suffices, and sometimes you need more +% than two; texi2dvi does it as many times as necessary. +% +% It is possible to adapt texinfo.tex for other languages, to some +% extent. You can get the existing language-specific files from the +% full Texinfo distribution. +% +% The GNU Texinfo home page is http://www.gnu.org/software/texinfo. + + +\message{Loading texinfo [version \texinfoversion]:} + +% If in a .fmt file, print the version number +% and turn on active characters that we couldn't do earlier because +% they might have appeared in the input file name. +\everyjob{\message{[Texinfo version \texinfoversion]}% + \catcode`+=\active \catcode`\_=\active} + +\message{Basics,} +\chardef\other=12 + +% We never want plain's \outer definition of \+ in Texinfo. +% For @tex, we can use \tabalign. +\let\+ = \relax + +% Save some plain tex macros whose names we will redefine. +\let\ptexb=\b +\let\ptexbullet=\bullet +\let\ptexc=\c +\let\ptexcomma=\, +\let\ptexdot=\. +\let\ptexdots=\dots +\let\ptexend=\end +\let\ptexequiv=\equiv +\let\ptexexclam=\! +\let\ptexfootnote=\footnote +\let\ptexgtr=> +\let\ptexhat=^ +\let\ptexi=\i +\let\ptexindent=\indent +\let\ptexinsert=\insert +\let\ptexlbrace=\{ +\let\ptexless=< +\let\ptexnewwrite\newwrite +\let\ptexnoindent=\noindent +\let\ptexplus=+ +\let\ptexrbrace=\} +\let\ptexslash=\/ +\let\ptexstar=\* +\let\ptext=\t + +% If this character appears in an error message or help string, it +% starts a new line in the output. +\newlinechar = `^^J + +% Use TeX 3.0's \inputlineno to get the line number, for better error +% messages, but if we're using an old version of TeX, don't do anything. +% +\ifx\inputlineno\thisisundefined + \let\linenumber = \empty % Pre-3.0. +\else + \def\linenumber{l.\the\inputlineno:\space} +\fi + +% Set up fixed words for English if not already set. +\ifx\putwordAppendix\undefined \gdef\putwordAppendix{Appendix}\fi +\ifx\putwordChapter\undefined \gdef\putwordChapter{Chapter}\fi +\ifx\putwordfile\undefined \gdef\putwordfile{file}\fi +\ifx\putwordin\undefined \gdef\putwordin{in}\fi +\ifx\putwordIndexIsEmpty\undefined \gdef\putwordIndexIsEmpty{(Index is empty)}\fi +\ifx\putwordIndexNonexistent\undefined \gdef\putwordIndexNonexistent{(Index is nonexistent)}\fi +\ifx\putwordInfo\undefined \gdef\putwordInfo{Info}\fi +\ifx\putwordInstanceVariableof\undefined \gdef\putwordInstanceVariableof{Instance Variable of}\fi +\ifx\putwordMethodon\undefined \gdef\putwordMethodon{Method on}\fi +\ifx\putwordNoTitle\undefined \gdef\putwordNoTitle{No Title}\fi +\ifx\putwordof\undefined \gdef\putwordof{of}\fi +\ifx\putwordon\undefined \gdef\putwordon{on}\fi +\ifx\putwordpage\undefined \gdef\putwordpage{page}\fi +\ifx\putwordsection\undefined \gdef\putwordsection{section}\fi +\ifx\putwordSection\undefined \gdef\putwordSection{Section}\fi +\ifx\putwordsee\undefined \gdef\putwordsee{see}\fi +\ifx\putwordSee\undefined \gdef\putwordSee{See}\fi +\ifx\putwordShortTOC\undefined \gdef\putwordShortTOC{Short Contents}\fi +\ifx\putwordTOC\undefined \gdef\putwordTOC{Table of Contents}\fi +% +\ifx\putwordMJan\undefined \gdef\putwordMJan{January}\fi +\ifx\putwordMFeb\undefined \gdef\putwordMFeb{February}\fi +\ifx\putwordMMar\undefined \gdef\putwordMMar{March}\fi +\ifx\putwordMApr\undefined \gdef\putwordMApr{April}\fi +\ifx\putwordMMay\undefined \gdef\putwordMMay{May}\fi +\ifx\putwordMJun\undefined \gdef\putwordMJun{June}\fi +\ifx\putwordMJul\undefined \gdef\putwordMJul{July}\fi +\ifx\putwordMAug\undefined \gdef\putwordMAug{August}\fi +\ifx\putwordMSep\undefined \gdef\putwordMSep{September}\fi +\ifx\putwordMOct\undefined \gdef\putwordMOct{October}\fi +\ifx\putwordMNov\undefined \gdef\putwordMNov{November}\fi +\ifx\putwordMDec\undefined \gdef\putwordMDec{December}\fi +% +\ifx\putwordDefmac\undefined \gdef\putwordDefmac{Macro}\fi +\ifx\putwordDefspec\undefined \gdef\putwordDefspec{Special Form}\fi +\ifx\putwordDefvar\undefined \gdef\putwordDefvar{Variable}\fi +\ifx\putwordDefopt\undefined \gdef\putwordDefopt{User Option}\fi +\ifx\putwordDeffunc\undefined \gdef\putwordDeffunc{Function}\fi + +% In some macros, we cannot use the `\? notation---the left quote is +% in some cases the escape char. +\chardef\colonChar = `\: +\chardef\commaChar = `\, +\chardef\dotChar = `\. +\chardef\exclamChar= `\! +\chardef\questChar = `\? +\chardef\semiChar = `\; +\chardef\underChar = `\_ + +\chardef\spaceChar = `\ % +\chardef\spacecat = 10 +\def\spaceisspace{\catcode\spaceChar=\spacecat} + +% Ignore a token. +% +\def\gobble#1{} + +% The following is used inside several \edef's. +\def\makecsname#1{\expandafter\noexpand\csname#1\endcsname} + +% Hyphenation fixes. +\hyphenation{ + Flor-i-da Ghost-script Ghost-view Mac-OS Post-Script + ap-pen-dix bit-map bit-maps + data-base data-bases eshell fall-ing half-way long-est man-u-script + man-u-scripts mini-buf-fer mini-buf-fers over-view par-a-digm + par-a-digms rath-er rec-tan-gu-lar ro-bot-ics se-vere-ly set-up spa-ces + spell-ing spell-ings + stand-alone strong-est time-stamp time-stamps which-ever white-space + wide-spread wrap-around +} + +% Margin to add to right of even pages, to left of odd pages. +\newdimen\bindingoffset +\newdimen\normaloffset +\newdimen\pagewidth \newdimen\pageheight + +% For a final copy, take out the rectangles +% that mark overfull boxes (in case you have decided +% that the text looks ok even though it passes the margin). +% +\def\finalout{\overfullrule=0pt} + +% @| inserts a changebar to the left of the current line. It should +% surround any changed text. This approach does *not* work if the +% change spans more than two lines of output. To handle that, we would +% have adopt a much more difficult approach (putting marks into the main +% vertical list for the beginning and end of each change). +% +\def\|{% + % \vadjust can only be used in horizontal mode. + \leavevmode + % + % Append this vertical mode material after the current line in the output. + \vadjust{% + % We want to insert a rule with the height and depth of the current + % leading; that is exactly what \strutbox is supposed to record. + \vskip-\baselineskip + % + % \vadjust-items are inserted at the left edge of the type. So + % the \llap here moves out into the left-hand margin. + \llap{% + % + % For a thicker or thinner bar, change the `1pt'. + \vrule height\baselineskip width1pt + % + % This is the space between the bar and the text. + \hskip 12pt + }% + }% +} + +% Sometimes it is convenient to have everything in the transcript file +% and nothing on the terminal. We don't just call \tracingall here, +% since that produces some useless output on the terminal. We also make +% some effort to order the tracing commands to reduce output in the log +% file; cf. trace.sty in LaTeX. +% +\def\gloggingall{\begingroup \globaldefs = 1 \loggingall \endgroup}% +\def\loggingall{% + \tracingstats2 + \tracingpages1 + \tracinglostchars2 % 2 gives us more in etex + \tracingparagraphs1 + \tracingoutput1 + \tracingmacros2 + \tracingrestores1 + \showboxbreadth\maxdimen \showboxdepth\maxdimen + \ifx\eTeXversion\undefined\else % etex gives us more logging + \tracingscantokens1 + \tracingifs1 + \tracinggroups1 + \tracingnesting2 + \tracingassigns1 + \fi + \tracingcommands3 % 3 gives us more in etex + \errorcontextlines16 +}% + +% add check for \lastpenalty to plain's definitions. If the last thing +% we did was a \nobreak, we don't want to insert more space. +% +\def\smallbreak{\ifnum\lastpenalty<10000\par\ifdim\lastskip<\smallskipamount + \removelastskip\penalty-50\smallskip\fi\fi} +\def\medbreak{\ifnum\lastpenalty<10000\par\ifdim\lastskip<\medskipamount + \removelastskip\penalty-100\medskip\fi\fi} +\def\bigbreak{\ifnum\lastpenalty<10000\par\ifdim\lastskip<\bigskipamount + \removelastskip\penalty-200\bigskip\fi\fi} + +% For @cropmarks command. +% Do @cropmarks to get crop marks. +% +\newif\ifcropmarks +\let\cropmarks = \cropmarkstrue +% +% Dimensions to add cropmarks at corners. +% Added by P. A. MacKay, 12 Nov. 1986 +% +\newdimen\outerhsize \newdimen\outervsize % set by the paper size routines +\newdimen\cornerlong \cornerlong=1pc +\newdimen\cornerthick \cornerthick=.3pt +\newdimen\topandbottommargin \topandbottommargin=.75in + +% Main output routine. +\chardef\PAGE = 255 +\output = {\onepageout{\pagecontents\PAGE}} + +\newbox\headlinebox +\newbox\footlinebox + +% \onepageout takes a vbox as an argument. Note that \pagecontents +% does insertions, but you have to call it yourself. +\def\onepageout#1{% + \ifcropmarks \hoffset=0pt \else \hoffset=\normaloffset \fi + % + \ifodd\pageno \advance\hoffset by \bindingoffset + \else \advance\hoffset by -\bindingoffset\fi + % + % Do this outside of the \shipout so @code etc. will be expanded in + % the headline as they should be, not taken literally (outputting ''code). + \setbox\headlinebox = \vbox{\let\hsize=\pagewidth \makeheadline}% + \setbox\footlinebox = \vbox{\let\hsize=\pagewidth \makefootline}% + % + {% + % Have to do this stuff outside the \shipout because we want it to + % take effect in \write's, yet the group defined by the \vbox ends + % before the \shipout runs. + % + \escapechar = `\\ % use backslash in output files. + \indexdummies % don't expand commands in the output. + \normalturnoffactive % \ in index entries must not stay \, e.g., if + % the page break happens to be in the middle of an example. + \shipout\vbox{% + % Do this early so pdf references go to the beginning of the page. + \ifpdfmakepagedest \pdfdest name{\the\pageno} xyz\fi + % + \ifcropmarks \vbox to \outervsize\bgroup + \hsize = \outerhsize + \vskip-\topandbottommargin + \vtop to0pt{% + \line{\ewtop\hfil\ewtop}% + \nointerlineskip + \line{% + \vbox{\moveleft\cornerthick\nstop}% + \hfill + \vbox{\moveright\cornerthick\nstop}% + }% + \vss}% + \vskip\topandbottommargin + \line\bgroup + \hfil % center the page within the outer (page) hsize. + \ifodd\pageno\hskip\bindingoffset\fi + \vbox\bgroup + \fi + % + \unvbox\headlinebox + \pagebody{#1}% + \ifdim\ht\footlinebox > 0pt + % Only leave this space if the footline is nonempty. + % (We lessened \vsize for it in \oddfootingxxx.) + % The \baselineskip=24pt in plain's \makefootline has no effect. + \vskip 2\baselineskip + \unvbox\footlinebox + \fi + % + \ifcropmarks + \egroup % end of \vbox\bgroup + \hfil\egroup % end of (centering) \line\bgroup + \vskip\topandbottommargin plus1fill minus1fill + \boxmaxdepth = \cornerthick + \vbox to0pt{\vss + \line{% + \vbox{\moveleft\cornerthick\nsbot}% + \hfill + \vbox{\moveright\cornerthick\nsbot}% + }% + \nointerlineskip + \line{\ewbot\hfil\ewbot}% + }% + \egroup % \vbox from first cropmarks clause + \fi + }% end of \shipout\vbox + }% end of group with \normalturnoffactive + \advancepageno + \ifnum\outputpenalty>-20000 \else\dosupereject\fi +} + +\newinsert\margin \dimen\margin=\maxdimen + +\def\pagebody#1{\vbox to\pageheight{\boxmaxdepth=\maxdepth #1}} +{\catcode`\@ =11 +\gdef\pagecontents#1{\ifvoid\topins\else\unvbox\topins\fi +% marginal hacks, juha@viisa.uucp (Juha Takala) +\ifvoid\margin\else % marginal info is present + \rlap{\kern\hsize\vbox to\z@{\kern1pt\box\margin \vss}}\fi +\dimen@=\dp#1 \unvbox#1 +\ifvoid\footins\else\vskip\skip\footins\footnoterule \unvbox\footins\fi +\ifr@ggedbottom \kern-\dimen@ \vfil \fi} +} + +% Here are the rules for the cropmarks. Note that they are +% offset so that the space between them is truly \outerhsize or \outervsize +% (P. A. MacKay, 12 November, 1986) +% +\def\ewtop{\vrule height\cornerthick depth0pt width\cornerlong} +\def\nstop{\vbox + {\hrule height\cornerthick depth\cornerlong width\cornerthick}} +\def\ewbot{\vrule height0pt depth\cornerthick width\cornerlong} +\def\nsbot{\vbox + {\hrule height\cornerlong depth\cornerthick width\cornerthick}} + +% Parse an argument, then pass it to #1. The argument is the rest of +% the input line (except we remove a trailing comment). #1 should be a +% macro which expects an ordinary undelimited TeX argument. +% +\def\parsearg{\parseargusing{}} +\def\parseargusing#1#2{% + \def\next{#2}% + \begingroup + \obeylines + \spaceisspace + #1% + \parseargline\empty% Insert the \empty token, see \finishparsearg below. +} + +{\obeylines % + \gdef\parseargline#1^^M{% + \endgroup % End of the group started in \parsearg. + \argremovecomment #1\comment\ArgTerm% + }% +} + +% First remove any @comment, then any @c comment. +\def\argremovecomment#1\comment#2\ArgTerm{\argremovec #1\c\ArgTerm} +\def\argremovec#1\c#2\ArgTerm{\argcheckspaces#1\^^M\ArgTerm} + +% Each occurence of `\^^M' or `\^^M' is replaced by a single space. +% +% \argremovec might leave us with trailing space, e.g., +% @end itemize @c foo +% This space token undergoes the same procedure and is eventually removed +% by \finishparsearg. +% +\def\argcheckspaces#1\^^M{\argcheckspacesX#1\^^M \^^M} +\def\argcheckspacesX#1 \^^M{\argcheckspacesY#1\^^M} +\def\argcheckspacesY#1\^^M#2\^^M#3\ArgTerm{% + \def\temp{#3}% + \ifx\temp\empty + % We cannot use \next here, as it holds the macro to run; + % thus we reuse \temp. + \let\temp\finishparsearg + \else + \let\temp\argcheckspaces + \fi + % Put the space token in: + \temp#1 #3\ArgTerm +} + +% If a _delimited_ argument is enclosed in braces, they get stripped; so +% to get _exactly_ the rest of the line, we had to prevent such situation. +% We prepended an \empty token at the very beginning and we expand it now, +% just before passing the control to \next. +% (Similarily, we have to think about #3 of \argcheckspacesY above: it is +% either the null string, or it ends with \^^M---thus there is no danger +% that a pair of braces would be stripped. +% +% But first, we have to remove the trailing space token. +% +\def\finishparsearg#1 \ArgTerm{\expandafter\next\expandafter{#1}} + +% \parseargdef\foo{...} +% is roughly equivalent to +% \def\foo{\parsearg\Xfoo} +% \def\Xfoo#1{...} +% +% Actually, I use \csname\string\foo\endcsname, ie. \\foo, as it is my +% favourite TeX trick. --kasal, 16nov03 + +\def\parseargdef#1{% + \expandafter \doparseargdef \csname\string#1\endcsname #1% +} +\def\doparseargdef#1#2{% + \def#2{\parsearg#1}% + \def#1##1% +} + +% Several utility definitions with active space: +{ + \obeyspaces + \gdef\obeyedspace{ } + + % Make each space character in the input produce a normal interword + % space in the output. Don't allow a line break at this space, as this + % is used only in environments like @example, where each line of input + % should produce a line of output anyway. + % + \gdef\sepspaces{\obeyspaces\let =\tie} + + % If an index command is used in an @example environment, any spaces + % therein should become regular spaces in the raw index file, not the + % expansion of \tie (\leavevmode \penalty \@M \ ). + \gdef\unsepspaces{\let =\space} +} + + +\def\flushcr{\ifx\par\lisppar \def\next##1{}\else \let\next=\relax \fi \next} + +% Define the framework for environments in texinfo.tex. It's used like this: +% +% \envdef\foo{...} +% \def\Efoo{...} +% +% It's the responsibility of \envdef to insert \begingroup before the +% actual body; @end closes the group after calling \Efoo. \envdef also +% defines \thisenv, so the current environment is known; @end checks +% whether the environment name matches. The \checkenv macro can also be +% used to check whether the current environment is the one expected. +% +% Non-false conditionals (@iftex, @ifset) don't fit into this, so they +% are not treated as enviroments; they don't open a group. (The +% implementation of @end takes care not to call \endgroup in this +% special case.) + + +% At runtime, environments start with this: +\def\startenvironment#1{\begingroup\def\thisenv{#1}} +% initialize +\let\thisenv\empty + +% ... but they get defined via ``\envdef\foo{...}'': +\long\def\envdef#1#2{\def#1{\startenvironment#1#2}} +\def\envparseargdef#1#2{\parseargdef#1{\startenvironment#1#2}} + +% Check whether we're in the right environment: +\def\checkenv#1{% + \def\temp{#1}% + \ifx\thisenv\temp + \else + \badenverr + \fi +} + +% Evironment mismatch, #1 expected: +\def\badenverr{% + \errhelp = \EMsimple + \errmessage{This command can appear only \inenvironment\temp, + not \inenvironment\thisenv}% +} +\def\inenvironment#1{% + \ifx#1\empty + out of any environment% + \else + in environment \expandafter\string#1% + \fi +} + +% @end foo executes the definition of \Efoo. +% But first, it executes a specialized version of \checkenv +% +\parseargdef\end{% + \if 1\csname iscond.#1\endcsname + \else + % The general wording of \badenverr may not be ideal, but... --kasal, 06nov03 + \expandafter\checkenv\csname#1\endcsname + \csname E#1\endcsname + \endgroup + \fi +} + +\newhelp\EMsimple{Press RETURN to continue.} + + +%% Simple single-character @ commands + +% @@ prints an @ +% Kludge this until the fonts are right (grr). +\def\@{{\tt\char64}} + +% This is turned off because it was never documented +% and you can use @w{...} around a quote to suppress ligatures. +%% Define @` and @' to be the same as ` and ' +%% but suppressing ligatures. +%\def\`{{`}} +%\def\'{{'}} + +% Used to generate quoted braces. +\def\mylbrace {{\tt\char123}} +\def\myrbrace {{\tt\char125}} +\let\{=\mylbrace +\let\}=\myrbrace +\begingroup + % Definitions to produce \{ and \} commands for indices, + % and @{ and @} for the aux file. + \catcode`\{ = \other \catcode`\} = \other + \catcode`\[ = 1 \catcode`\] = 2 + \catcode`\! = 0 \catcode`\\ = \other + !gdef!lbracecmd[\{]% + !gdef!rbracecmd[\}]% + !gdef!lbraceatcmd[@{]% + !gdef!rbraceatcmd[@}]% +!endgroup + +% @comma{} to avoid , parsing problems. +\let\comma = , + +% Accents: @, @dotaccent @ringaccent @ubaraccent @udotaccent +% Others are defined by plain TeX: @` @' @" @^ @~ @= @u @v @H. +\let\, = \c +\let\dotaccent = \. +\def\ringaccent#1{{\accent23 #1}} +\let\tieaccent = \t +\let\ubaraccent = \b +\let\udotaccent = \d + +% Other special characters: @questiondown @exclamdown @ordf @ordm +% Plain TeX defines: @AA @AE @O @OE @L (plus lowercase versions) @ss. +\def\questiondown{?`} +\def\exclamdown{!`} +\def\ordf{\leavevmode\raise1ex\hbox{\selectfonts\lllsize \underbar{a}}} +\def\ordm{\leavevmode\raise1ex\hbox{\selectfonts\lllsize \underbar{o}}} + +% Dotless i and dotless j, used for accents. +\def\imacro{i} +\def\jmacro{j} +\def\dotless#1{% + \def\temp{#1}% + \ifx\temp\imacro \ptexi + \else\ifx\temp\jmacro \j + \else \errmessage{@dotless can be used only with i or j}% + \fi\fi +} + +% The \TeX{} logo, as in plain, but resetting the spacing so that a +% period following counts as ending a sentence. (Idea found in latex.) +% +\edef\TeX{\TeX \spacefactor=1000 } + +% @LaTeX{} logo. Not quite the same results as the definition in +% latex.ltx, since we use a different font for the raised A; it's most +% convenient for us to use an explicitly smaller font, rather than using +% the \scriptstyle font (since we don't reset \scriptstyle and +% \scriptscriptstyle). +% +\def\LaTeX{% + L\kern-.36em + {\setbox0=\hbox{T}% + \vbox to \ht0{\hbox{\selectfonts\lllsize A}\vss}}% + \kern-.15em + \TeX +} + +% Be sure we're in horizontal mode when doing a tie, since we make space +% equivalent to this in @example-like environments. Otherwise, a space +% at the beginning of a line will start with \penalty -- and +% since \penalty is valid in vertical mode, we'd end up putting the +% penalty on the vertical list instead of in the new paragraph. +{\catcode`@ = 11 + % Avoid using \@M directly, because that causes trouble + % if the definition is written into an index file. + \global\let\tiepenalty = \@M + \gdef\tie{\leavevmode\penalty\tiepenalty\ } +} + +% @: forces normal size whitespace following. +\def\:{\spacefactor=1000 } + +% @* forces a line break. +\def\*{\hfil\break\hbox{}\ignorespaces} + +% @/ allows a line break. +\let\/=\allowbreak + +% @. is an end-of-sentence period. +\def\.{.\spacefactor=3000 } + +% @! is an end-of-sentence bang. +\def\!{!\spacefactor=3000 } + +% @? is an end-of-sentence query. +\def\?{?\spacefactor=3000 } + +% @w prevents a word break. Without the \leavevmode, @w at the +% beginning of a paragraph, when TeX is still in vertical mode, would +% produce a whole line of output instead of starting the paragraph. +\def\w#1{\leavevmode\hbox{#1}} + +% @group ... @end group forces ... to be all on one page, by enclosing +% it in a TeX vbox. We use \vtop instead of \vbox to construct the box +% to keep its height that of a normal line. According to the rules for +% \topskip (p.114 of the TeXbook), the glue inserted is +% max (\topskip - \ht (first item), 0). If that height is large, +% therefore, no glue is inserted, and the space between the headline and +% the text is small, which looks bad. +% +% Another complication is that the group might be very large. This can +% cause the glue on the previous page to be unduly stretched, because it +% does not have much material. In this case, it's better to add an +% explicit \vfill so that the extra space is at the bottom. The +% threshold for doing this is if the group is more than \vfilllimit +% percent of a page (\vfilllimit can be changed inside of @tex). +% +\newbox\groupbox +\def\vfilllimit{0.7} +% +\envdef\group{% + \ifnum\catcode`\^^M=\active \else + \errhelp = \groupinvalidhelp + \errmessage{@group invalid in context where filling is enabled}% + \fi + \startsavinginserts + % + \setbox\groupbox = \vtop\bgroup + % Do @comment since we are called inside an environment such as + % @example, where each end-of-line in the input causes an + % end-of-line in the output. We don't want the end-of-line after + % the `@group' to put extra space in the output. Since @group + % should appear on a line by itself (according to the Texinfo + % manual), we don't worry about eating any user text. + \comment +} +% +% The \vtop produces a box with normal height and large depth; thus, TeX puts +% \baselineskip glue before it, and (when the next line of text is done) +% \lineskip glue after it. Thus, space below is not quite equal to space +% above. But it's pretty close. +\def\Egroup{% + % To get correct interline space between the last line of the group + % and the first line afterwards, we have to propagate \prevdepth. + \endgraf % Not \par, as it may have been set to \lisppar. + \global\dimen1 = \prevdepth + \egroup % End the \vtop. + % \dimen0 is the vertical size of the group's box. + \dimen0 = \ht\groupbox \advance\dimen0 by \dp\groupbox + % \dimen2 is how much space is left on the page (more or less). + \dimen2 = \pageheight \advance\dimen2 by -\pagetotal + % if the group doesn't fit on the current page, and it's a big big + % group, force a page break. + \ifdim \dimen0 > \dimen2 + \ifdim \pagetotal < \vfilllimit\pageheight + \page + \fi + \fi + \box\groupbox + \prevdepth = \dimen1 + \checkinserts +} +% +% TeX puts in an \escapechar (i.e., `@') at the beginning of the help +% message, so this ends up printing `@group can only ...'. +% +\newhelp\groupinvalidhelp{% +group can only be used in environments such as @example,^^J% +where each line of input produces a line of output.} + +% @need space-in-mils +% forces a page break if there is not space-in-mils remaining. + +\newdimen\mil \mil=0.001in + +% Old definition--didn't work. +%\parseargdef\need{\par % +%% This method tries to make TeX break the page naturally +%% if the depth of the box does not fit. +%{\baselineskip=0pt% +%\vtop to #1\mil{\vfil}\kern -#1\mil\nobreak +%\prevdepth=-1000pt +%}} + +\parseargdef\need{% + % Ensure vertical mode, so we don't make a big box in the middle of a + % paragraph. + \par + % + % If the @need value is less than one line space, it's useless. + \dimen0 = #1\mil + \dimen2 = \ht\strutbox + \advance\dimen2 by \dp\strutbox + \ifdim\dimen0 > \dimen2 + % + % Do a \strut just to make the height of this box be normal, so the + % normal leading is inserted relative to the preceding line. + % And a page break here is fine. + \vtop to #1\mil{\strut\vfil}% + % + % TeX does not even consider page breaks if a penalty added to the + % main vertical list is 10000 or more. But in order to see if the + % empty box we just added fits on the page, we must make it consider + % page breaks. On the other hand, we don't want to actually break the + % page after the empty box. So we use a penalty of 9999. + % + % There is an extremely small chance that TeX will actually break the + % page at this \penalty, if there are no other feasible breakpoints in + % sight. (If the user is using lots of big @group commands, which + % almost-but-not-quite fill up a page, TeX will have a hard time doing + % good page breaking, for example.) However, I could not construct an + % example where a page broke at this \penalty; if it happens in a real + % document, then we can reconsider our strategy. + \penalty9999 + % + % Back up by the size of the box, whether we did a page break or not. + \kern -#1\mil + % + % Do not allow a page break right after this kern. + \nobreak + \fi +} + +% @br forces paragraph break (and is undocumented). + +\let\br = \par + +% @page forces the start of a new page. +% +\def\page{\par\vfill\supereject} + +% @exdent text.... +% outputs text on separate line in roman font, starting at standard page margin + +% This records the amount of indent in the innermost environment. +% That's how much \exdent should take out. +\newskip\exdentamount + +% This defn is used inside fill environments such as @defun. +\parseargdef\exdent{\hfil\break\hbox{\kern -\exdentamount{\rm#1}}\hfil\break} + +% This defn is used inside nofill environments such as @example. +\parseargdef\nofillexdent{{\advance \leftskip by -\exdentamount + \leftline{\hskip\leftskip{\rm#1}}}} + +% @inmargin{WHICH}{TEXT} puts TEXT in the WHICH margin next to the current +% paragraph. For more general purposes, use the \margin insertion +% class. WHICH is `l' or `r'. +% +\newskip\inmarginspacing \inmarginspacing=1cm +\def\strutdepth{\dp\strutbox} +% +\def\doinmargin#1#2{\strut\vadjust{% + \nobreak + \kern-\strutdepth + \vtop to \strutdepth{% + \baselineskip=\strutdepth + \vss + % if you have multiple lines of stuff to put here, you'll need to + % make the vbox yourself of the appropriate size. + \ifx#1l% + \llap{\ignorespaces #2\hskip\inmarginspacing}% + \else + \rlap{\hskip\hsize \hskip\inmarginspacing \ignorespaces #2}% + \fi + \null + }% +}} +\def\inleftmargin{\doinmargin l} +\def\inrightmargin{\doinmargin r} +% +% @inmargin{TEXT [, RIGHT-TEXT]} +% (if RIGHT-TEXT is given, use TEXT for left page, RIGHT-TEXT for right; +% else use TEXT for both). +% +\def\inmargin#1{\parseinmargin #1,,\finish} +\def\parseinmargin#1,#2,#3\finish{% not perfect, but better than nothing. + \setbox0 = \hbox{\ignorespaces #2}% + \ifdim\wd0 > 0pt + \def\lefttext{#1}% have both texts + \def\righttext{#2}% + \else + \def\lefttext{#1}% have only one text + \def\righttext{#1}% + \fi + % + \ifodd\pageno + \def\temp{\inrightmargin\righttext}% odd page -> outside is right margin + \else + \def\temp{\inleftmargin\lefttext}% + \fi + \temp +} + +% @include file insert text of that file as input. +% +\def\include{\parseargusing\filenamecatcodes\includezzz} +\def\includezzz#1{% + \pushthisfilestack + \def\thisfile{#1}% + {% + \makevalueexpandable + \def\temp{\input #1 }% + \expandafter + }\temp + \popthisfilestack +} +\def\filenamecatcodes{% + \catcode`\\=\other + \catcode`~=\other + \catcode`^=\other + \catcode`_=\other + \catcode`|=\other + \catcode`<=\other + \catcode`>=\other + \catcode`+=\other + \catcode`-=\other +} + +\def\pushthisfilestack{% + \expandafter\pushthisfilestackX\popthisfilestack\StackTerm +} +\def\pushthisfilestackX{% + \expandafter\pushthisfilestackY\thisfile\StackTerm +} +\def\pushthisfilestackY #1\StackTerm #2\StackTerm {% + \gdef\popthisfilestack{\gdef\thisfile{#1}\gdef\popthisfilestack{#2}}% +} + +\def\popthisfilestack{\errthisfilestackempty} +\def\errthisfilestackempty{\errmessage{Internal error: + the stack of filenames is empty.}} + +\def\thisfile{} + +% @center line +% outputs that line, centered. +% +\parseargdef\center{% + \ifhmode + \let\next\centerH + \else + \let\next\centerV + \fi + \next{\hfil \ignorespaces#1\unskip \hfil}% +} +\def\centerH#1{% + {% + \hfil\break + \advance\hsize by -\leftskip + \advance\hsize by -\rightskip + \line{#1}% + \break + }% +} +\def\centerV#1{\line{\kern\leftskip #1\kern\rightskip}} + +% @sp n outputs n lines of vertical space + +\parseargdef\sp{\vskip #1\baselineskip} + +% @comment ...line which is ignored... +% @c is the same as @comment +% @ignore ... @end ignore is another way to write a comment + +\def\comment{\begingroup \catcode`\^^M=\other% +\catcode`\@=\other \catcode`\{=\other \catcode`\}=\other% +\commentxxx} +{\catcode`\^^M=\other \gdef\commentxxx#1^^M{\endgroup}} + +\let\c=\comment + +% @paragraphindent NCHARS +% We'll use ems for NCHARS, close enough. +% NCHARS can also be the word `asis' or `none'. +% We cannot feasibly implement @paragraphindent asis, though. +% +\def\asisword{asis} % no translation, these are keywords +\def\noneword{none} +% +\parseargdef\paragraphindent{% + \def\temp{#1}% + \ifx\temp\asisword + \else + \ifx\temp\noneword + \defaultparindent = 0pt + \else + \defaultparindent = #1em + \fi + \fi + \parindent = \defaultparindent +} + +% @exampleindent NCHARS +% We'll use ems for NCHARS like @paragraphindent. +% It seems @exampleindent asis isn't necessary, but +% I preserve it to make it similar to @paragraphindent. +\parseargdef\exampleindent{% + \def\temp{#1}% + \ifx\temp\asisword + \else + \ifx\temp\noneword + \lispnarrowing = 0pt + \else + \lispnarrowing = #1em + \fi + \fi +} + +% @firstparagraphindent WORD +% If WORD is `none', then suppress indentation of the first paragraph +% after a section heading. If WORD is `insert', then do indent at such +% paragraphs. +% +% The paragraph indentation is suppressed or not by calling +% \suppressfirstparagraphindent, which the sectioning commands do. +% We switch the definition of this back and forth according to WORD. +% By default, we suppress indentation. +% +\def\suppressfirstparagraphindent{\dosuppressfirstparagraphindent} +\def\insertword{insert} +% +\parseargdef\firstparagraphindent{% + \def\temp{#1}% + \ifx\temp\noneword + \let\suppressfirstparagraphindent = \dosuppressfirstparagraphindent + \else\ifx\temp\insertword + \let\suppressfirstparagraphindent = \relax + \else + \errhelp = \EMsimple + \errmessage{Unknown @firstparagraphindent option `\temp'}% + \fi\fi +} + +% Here is how we actually suppress indentation. Redefine \everypar to +% \kern backwards by \parindent, and then reset itself to empty. +% +% We also make \indent itself not actually do anything until the next +% paragraph. +% +\gdef\dosuppressfirstparagraphindent{% + \gdef\indent{% + \restorefirstparagraphindent + \indent + }% + \gdef\noindent{% + \restorefirstparagraphindent + \noindent + }% + \global\everypar = {% + \kern -\parindent + \restorefirstparagraphindent + }% +} + +\gdef\restorefirstparagraphindent{% + \global \let \indent = \ptexindent + \global \let \noindent = \ptexnoindent + \global \everypar = {}% +} + + +% @asis just yields its argument. Used with @table, for example. +% +\def\asis#1{#1} + +% @math outputs its argument in math mode. +% +% One complication: _ usually means subscripts, but it could also mean +% an actual _ character, as in @math{@var{some_variable} + 1}. So make +% _ active, and distinguish by seeing if the current family is \slfam, +% which is what @var uses. +{ + \catcode\underChar = \active + \gdef\mathunderscore{% + \catcode\underChar=\active + \def_{\ifnum\fam=\slfam \_\else\sb\fi}% + } +} +% Another complication: we want \\ (and @\) to output a \ character. +% FYI, plain.tex uses \\ as a temporary control sequence (why?), but +% this is not advertised and we don't care. Texinfo does not +% otherwise define @\. +% +% The \mathchar is class=0=ordinary, family=7=ttfam, position=5C=\. +\def\mathbackslash{\ifnum\fam=\ttfam \mathchar"075C \else\backslash \fi} +% +\def\math{% + \tex + \mathunderscore + \let\\ = \mathbackslash + \mathactive + $\finishmath +} +\def\finishmath#1{#1$\endgroup} % Close the group opened by \tex. + +% Some active characters (such as <) are spaced differently in math. +% We have to reset their definitions in case the @math was an argument +% to a command which sets the catcodes (such as @item or @section). +% +{ + \catcode`^ = \active + \catcode`< = \active + \catcode`> = \active + \catcode`+ = \active + \gdef\mathactive{% + \let^ = \ptexhat + \let< = \ptexless + \let> = \ptexgtr + \let+ = \ptexplus + } +} + +% @bullet and @minus need the same treatment as @math, just above. +\def\bullet{$\ptexbullet$} +\def\minus{$-$} + +% @dots{} outputs an ellipsis using the current font. +% We do .5em per period so that it has the same spacing in a typewriter +% font as three actual period characters. +% +\def\dots{% + \leavevmode + \hbox to 1.5em{% + \hskip 0pt plus 0.25fil + .\hfil.\hfil.% + \hskip 0pt plus 0.5fil + }% +} + +% @enddots{} is an end-of-sentence ellipsis. +% +\def\enddots{% + \dots + \spacefactor=3000 +} + +% @comma{} is so commas can be inserted into text without messing up +% Texinfo's parsing. +% +\let\comma = , + +% @refill is a no-op. +\let\refill=\relax + +% If working on a large document in chapters, it is convenient to +% be able to disable indexing, cross-referencing, and contents, for test runs. +% This is done with @novalidate (before @setfilename). +% +\newif\iflinks \linkstrue % by default we want the aux files. +\let\novalidate = \linksfalse + +% @setfilename is done at the beginning of every texinfo file. +% So open here the files we need to have open while reading the input. +% This makes it possible to make a .fmt file for texinfo. +\def\setfilename{% + \fixbackslash % Turn off hack to swallow `\input texinfo'. + \iflinks + \tryauxfile + % Open the new aux file. TeX will close it automatically at exit. + \immediate\openout\auxfile=\jobname.aux + \fi % \openindices needs to do some work in any case. + \openindices + \let\setfilename=\comment % Ignore extra @setfilename cmds. + % + % If texinfo.cnf is present on the system, read it. + % Useful for site-wide @afourpaper, etc. + \openin 1 texinfo.cnf + \ifeof 1 \else \input texinfo.cnf \fi + \closein 1 + % + \comment % Ignore the actual filename. +} + +% Called from \setfilename. +% +\def\openindices{% + \newindex{cp}% + \newcodeindex{fn}% + \newcodeindex{vr}% + \newcodeindex{tp}% + \newcodeindex{ky}% + \newcodeindex{pg}% +} + +% @bye. +\outer\def\bye{\pagealignmacro\tracingstats=1\ptexend} + + +\message{pdf,} +% adobe `portable' document format +\newcount\tempnum +\newcount\lnkcount +\newtoks\filename +\newcount\filenamelength +\newcount\pgn +\newtoks\toksA +\newtoks\toksB +\newtoks\toksC +\newtoks\toksD +\newbox\boxA +\newcount\countA +\newif\ifpdf +\newif\ifpdfmakepagedest + +% when pdftex is run in dvi mode, \pdfoutput is defined (so \pdfoutput=1 +% can be set). So we test for \relax and 0 as well as \undefined, +% borrowed from ifpdf.sty. +\ifx\pdfoutput\undefined +\else + \ifx\pdfoutput\relax + \else + \ifcase\pdfoutput + \else + \pdftrue + \fi + \fi +\fi +% +\ifpdf + \input pdfcolor + \pdfcatalog{/PageMode /UseOutlines}% + \def\dopdfimage#1#2#3{% + \def\imagewidth{#2}% + \def\imageheight{#3}% + % without \immediate, pdftex seg faults when the same image is + % included twice. (Version 3.14159-pre-1.0-unofficial-20010704.) + \ifnum\pdftexversion < 14 + \immediate\pdfimage + \else + \immediate\pdfximage + \fi + \ifx\empty\imagewidth\else width \imagewidth \fi + \ifx\empty\imageheight\else height \imageheight \fi + \ifnum\pdftexversion<13 + #1.pdf% + \else + {#1.pdf}% + \fi + \ifnum\pdftexversion < 14 \else + \pdfrefximage \pdflastximage + \fi} + \def\pdfmkdest#1{{% + % We have to set dummies so commands such as @code in a section title + % aren't expanded. + \atdummies + \normalturnoffactive + \pdfdest name{#1} xyz% + }} + \def\pdfmkpgn#1{#1} + \let\linkcolor = \Blue % was Cyan, but that seems light? + \def\endlink{\Black\pdfendlink} + % Adding outlines to PDF; macros for calculating structure of outlines + % come from Petr Olsak + \def\expnumber#1{\expandafter\ifx\csname#1\endcsname\relax 0% + \else \csname#1\endcsname \fi} + \def\advancenumber#1{\tempnum=\expnumber{#1}\relax + \advance\tempnum by 1 + \expandafter\xdef\csname#1\endcsname{\the\tempnum}} + % + % #1 is the section text. #2 is the pdf expression for the number + % of subentries (or empty, for subsubsections). #3 is the node + % text, which might be empty if this toc entry had no + % corresponding node. #4 is the page number. + % + \def\dopdfoutline#1#2#3#4{% + % Generate a link to the node text if that exists; else, use the + % page number. We could generate a destination for the section + % text in the case where a section has no node, but it doesn't + % seem worthwhile, since most documents are normally structured. + \def\pdfoutlinedest{#3}% + \ifx\pdfoutlinedest\empty \def\pdfoutlinedest{#4}\fi + % + \pdfoutline goto name{\pdfmkpgn{\pdfoutlinedest}}#2{#1}% + } + % + \def\pdfmakeoutlines{% + \begingroup + % Thanh's hack / proper braces in bookmarks + \edef\mylbrace{\iftrue \string{\else}\fi}\let\{=\mylbrace + \edef\myrbrace{\iffalse{\else\string}\fi}\let\}=\myrbrace + % + % Read toc silently, to get counts of subentries for \pdfoutline. + \def\numchapentry##1##2##3##4{% + \def\thischapnum{##2}% + \def\thissecnum{0}% + \def\thissubsecnum{0}% + }% + \def\numsecentry##1##2##3##4{% + \advancenumber{chap\thischapnum}% + \def\thissecnum{##2}% + \def\thissubsecnum{0}% + }% + \def\numsubsecentry##1##2##3##4{% + \advancenumber{sec\thissecnum}% + \def\thissubsecnum{##2}% + }% + \def\numsubsubsecentry##1##2##3##4{% + \advancenumber{subsec\thissubsecnum}% + }% + \def\thischapnum{0}% + \def\thissecnum{0}% + \def\thissubsecnum{0}% + % + % use \def rather than \let here because we redefine \chapentry et + % al. a second time, below. + \def\appentry{\numchapentry}% + \def\appsecentry{\numsecentry}% + \def\appsubsecentry{\numsubsecentry}% + \def\appsubsubsecentry{\numsubsubsecentry}% + \def\unnchapentry{\numchapentry}% + \def\unnsecentry{\numsecentry}% + \def\unnsubsecentry{\numsubsecentry}% + \def\unnsubsubsecentry{\numsubsubsecentry}% + \input \jobname.toc + % + % Read toc second time, this time actually producing the outlines. + % The `-' means take the \expnumber as the absolute number of + % subentries, which we calculated on our first read of the .toc above. + % + % We use the node names as the destinations. + \def\numchapentry##1##2##3##4{% + \dopdfoutline{##1}{count-\expnumber{chap##2}}{##3}{##4}}% + \def\numsecentry##1##2##3##4{% + \dopdfoutline{##1}{count-\expnumber{sec##2}}{##3}{##4}}% + \def\numsubsecentry##1##2##3##4{% + \dopdfoutline{##1}{count-\expnumber{subsec##2}}{##3}{##4}}% + \def\numsubsubsecentry##1##2##3##4{% count is always zero + \dopdfoutline{##1}{}{##3}{##4}}% + % + % PDF outlines are displayed using system fonts, instead of + % document fonts. Therefore we cannot use special characters, + % since the encoding is unknown. For example, the eogonek from + % Latin 2 (0xea) gets translated to a | character. Info from + % Staszek Wawrykiewicz, 19 Jan 2004 04:09:24 +0100. + % + % xx to do this right, we have to translate 8-bit characters to + % their "best" equivalent, based on the @documentencoding. Right + % now, I guess we'll just let the pdf reader have its way. + \indexnofonts + \turnoffactive + \input \jobname.toc + \endgroup + } + % + \def\makelinks #1,{% + \def\params{#1}\def\E{END}% + \ifx\params\E + \let\nextmakelinks=\relax + \else + \let\nextmakelinks=\makelinks + \ifnum\lnkcount>0,\fi + \picknum{#1}% + \startlink attr{/Border [0 0 0]} + goto name{\pdfmkpgn{\the\pgn}}% + \linkcolor #1% + \advance\lnkcount by 1% + \endlink + \fi + \nextmakelinks + } + \def\picknum#1{\expandafter\pn#1} + \def\pn#1{% + \def\p{#1}% + \ifx\p\lbrace + \let\nextpn=\ppn + \else + \let\nextpn=\ppnn + \def\first{#1} + \fi + \nextpn + } + \def\ppn#1{\pgn=#1\gobble} + \def\ppnn{\pgn=\first} + \def\pdfmklnk#1{\lnkcount=0\makelinks #1,END,} + \def\skipspaces#1{\def\PP{#1}\def\D{|}% + \ifx\PP\D\let\nextsp\relax + \else\let\nextsp\skipspaces + \ifx\p\space\else\addtokens{\filename}{\PP}% + \advance\filenamelength by 1 + \fi + \fi + \nextsp} + \def\getfilename#1{\filenamelength=0\expandafter\skipspaces#1|\relax} + \ifnum\pdftexversion < 14 + \let \startlink \pdfannotlink + \else + \let \startlink \pdfstartlink + \fi + \def\pdfurl#1{% + \begingroup + \normalturnoffactive\def\@{@}% + \makevalueexpandable + \leavevmode\Red + \startlink attr{/Border [0 0 0]}% + user{/Subtype /Link /A << /S /URI /URI (#1) >>}% + \endgroup} + \def\pdfgettoks#1.{\setbox\boxA=\hbox{\toksA={#1.}\toksB={}\maketoks}} + \def\addtokens#1#2{\edef\addtoks{\noexpand#1={\the#1#2}}\addtoks} + \def\adn#1{\addtokens{\toksC}{#1}\global\countA=1\let\next=\maketoks} + \def\poptoks#1#2|ENDTOKS|{\let\first=#1\toksD={#1}\toksA={#2}} + \def\maketoks{% + \expandafter\poptoks\the\toksA|ENDTOKS|\relax + \ifx\first0\adn0 + \else\ifx\first1\adn1 \else\ifx\first2\adn2 \else\ifx\first3\adn3 + \else\ifx\first4\adn4 \else\ifx\first5\adn5 \else\ifx\first6\adn6 + \else\ifx\first7\adn7 \else\ifx\first8\adn8 \else\ifx\first9\adn9 + \else + \ifnum0=\countA\else\makelink\fi + \ifx\first.\let\next=\done\else + \let\next=\maketoks + \addtokens{\toksB}{\the\toksD} + \ifx\first,\addtokens{\toksB}{\space}\fi + \fi + \fi\fi\fi\fi\fi\fi\fi\fi\fi\fi + \next} + \def\makelink{\addtokens{\toksB}% + {\noexpand\pdflink{\the\toksC}}\toksC={}\global\countA=0} + \def\pdflink#1{% + \startlink attr{/Border [0 0 0]} goto name{\pdfmkpgn{#1}} + \linkcolor #1\endlink} + \def\done{\edef\st{\global\noexpand\toksA={\the\toksB}}\st} +\else + \let\pdfmkdest = \gobble + \let\pdfurl = \gobble + \let\endlink = \relax + \let\linkcolor = \relax + \let\pdfmakeoutlines = \relax +\fi % \ifx\pdfoutput + + +\message{fonts,} + +% Change the current font style to #1, remembering it in \curfontstyle. +% For now, we do not accumulate font styles: @b{@i{foo}} prints foo in +% italics, not bold italics. +% +\def\setfontstyle#1{% + \def\curfontstyle{#1}% not as a control sequence, because we are \edef'd. + \csname ten#1\endcsname % change the current font +} + +% Select #1 fonts with the current style. +% +\def\selectfonts#1{\csname #1fonts\endcsname \csname\curfontstyle\endcsname} + +\def\rm{\fam=0 \setfontstyle{rm}} +\def\it{\fam=\itfam \setfontstyle{it}} +\def\sl{\fam=\slfam \setfontstyle{sl}} +\def\bf{\fam=\bffam \setfontstyle{bf}}\def\bfstylename{bf} +\def\tt{\fam=\ttfam \setfontstyle{tt}} + +% Texinfo sort of supports the sans serif font style, which plain TeX does not. +% So we set up a \sf. +\newfam\sffam +\def\sf{\fam=\sffam \setfontstyle{sf}} +\let\li = \sf % Sometimes we call it \li, not \sf. + +% We don't need math for this font style. +\def\ttsl{\setfontstyle{ttsl}} + +% Default leading. +\newdimen\textleading \textleading = 13.2pt + +% Set the baselineskip to #1, and the lineskip and strut size +% correspondingly. There is no deep meaning behind these magic numbers +% used as factors; they just match (closely enough) what Knuth defined. +% +\def\lineskipfactor{.08333} +\def\strutheightpercent{.70833} +\def\strutdepthpercent {.29167} +% +\def\setleading#1{% + \normalbaselineskip = #1\relax + \normallineskip = \lineskipfactor\normalbaselineskip + \normalbaselines + \setbox\strutbox =\hbox{% + \vrule width0pt height\strutheightpercent\baselineskip + depth \strutdepthpercent \baselineskip + }% +} + +% Set the font macro #1 to the font named #2, adding on the +% specified font prefix (normally `cm'). +% #3 is the font's design size, #4 is a scale factor +\def\setfont#1#2#3#4{\font#1=\fontprefix#2#3 scaled #4} + +% Use cm as the default font prefix. +% To specify the font prefix, you must define \fontprefix +% before you read in texinfo.tex. +\ifx\fontprefix\undefined +\def\fontprefix{cm} +\fi +% Support font families that don't use the same naming scheme as CM. +\def\rmshape{r} +\def\rmbshape{bx} %where the normal face is bold +\def\bfshape{b} +\def\bxshape{bx} +\def\ttshape{tt} +\def\ttbshape{tt} +\def\ttslshape{sltt} +\def\itshape{ti} +\def\itbshape{bxti} +\def\slshape{sl} +\def\slbshape{bxsl} +\def\sfshape{ss} +\def\sfbshape{ss} +\def\scshape{csc} +\def\scbshape{csc} + +% Text fonts (11.2pt, magstep1). +\def\textnominalsize{11pt} +\edef\mainmagstep{\magstephalf} +\setfont\textrm\rmshape{10}{\mainmagstep} +\setfont\texttt\ttshape{10}{\mainmagstep} +\setfont\textbf\bfshape{10}{\mainmagstep} +\setfont\textit\itshape{10}{\mainmagstep} +\setfont\textsl\slshape{10}{\mainmagstep} +\setfont\textsf\sfshape{10}{\mainmagstep} +\setfont\textsc\scshape{10}{\mainmagstep} +\setfont\textttsl\ttslshape{10}{\mainmagstep} +\font\texti=cmmi10 scaled \mainmagstep +\font\textsy=cmsy10 scaled \mainmagstep + +% A few fonts for @defun names and args. +\setfont\defbf\bfshape{10}{\magstep1} +\setfont\deftt\ttshape{10}{\magstep1} +\setfont\defttsl\ttslshape{10}{\magstep1} +\def\df{\let\tentt=\deftt \let\tenbf = \defbf \let\tenttsl=\defttsl \bf} + +% Fonts for indices, footnotes, small examples (9pt). +\def\smallnominalsize{9pt} +\setfont\smallrm\rmshape{9}{1000} +\setfont\smalltt\ttshape{9}{1000} +\setfont\smallbf\bfshape{10}{900} +\setfont\smallit\itshape{9}{1000} +\setfont\smallsl\slshape{9}{1000} +\setfont\smallsf\sfshape{9}{1000} +\setfont\smallsc\scshape{10}{900} +\setfont\smallttsl\ttslshape{10}{900} +\font\smalli=cmmi9 +\font\smallsy=cmsy9 + +% Fonts for small examples (8pt). +\def\smallernominalsize{8pt} +\setfont\smallerrm\rmshape{8}{1000} +\setfont\smallertt\ttshape{8}{1000} +\setfont\smallerbf\bfshape{10}{800} +\setfont\smallerit\itshape{8}{1000} +\setfont\smallersl\slshape{8}{1000} +\setfont\smallersf\sfshape{8}{1000} +\setfont\smallersc\scshape{10}{800} +\setfont\smallerttsl\ttslshape{10}{800} +\font\smalleri=cmmi8 +\font\smallersy=cmsy8 + +% Fonts for title page (20.4pt): +\def\titlenominalsize{20pt} +\setfont\titlerm\rmbshape{12}{\magstep3} +\setfont\titleit\itbshape{10}{\magstep4} +\setfont\titlesl\slbshape{10}{\magstep4} +\setfont\titlett\ttbshape{12}{\magstep3} +\setfont\titlettsl\ttslshape{10}{\magstep4} +\setfont\titlesf\sfbshape{17}{\magstep1} +\let\titlebf=\titlerm +\setfont\titlesc\scbshape{10}{\magstep4} +\font\titlei=cmmi12 scaled \magstep3 +\font\titlesy=cmsy10 scaled \magstep4 +\def\authorrm{\secrm} +\def\authortt{\sectt} + +% Chapter (and unnumbered) fonts (17.28pt). +\def\chapnominalsize{17pt} +\setfont\chaprm\rmbshape{12}{\magstep2} +\setfont\chapit\itbshape{10}{\magstep3} +\setfont\chapsl\slbshape{10}{\magstep3} +\setfont\chaptt\ttbshape{12}{\magstep2} +\setfont\chapttsl\ttslshape{10}{\magstep3} +\setfont\chapsf\sfbshape{17}{1000} +\let\chapbf=\chaprm +\setfont\chapsc\scbshape{10}{\magstep3} +\font\chapi=cmmi12 scaled \magstep2 +\font\chapsy=cmsy10 scaled \magstep3 + +% Section fonts (14.4pt). +\def\secnominalsize{14pt} +\setfont\secrm\rmbshape{12}{\magstep1} +\setfont\secit\itbshape{10}{\magstep2} +\setfont\secsl\slbshape{10}{\magstep2} +\setfont\sectt\ttbshape{12}{\magstep1} +\setfont\secttsl\ttslshape{10}{\magstep2} +\setfont\secsf\sfbshape{12}{\magstep1} +\let\secbf\secrm +\setfont\secsc\scbshape{10}{\magstep2} +\font\seci=cmmi12 scaled \magstep1 +\font\secsy=cmsy10 scaled \magstep2 + +% Subsection fonts (13.15pt). +\def\ssecnominalsize{13pt} +\setfont\ssecrm\rmbshape{12}{\magstephalf} +\setfont\ssecit\itbshape{10}{1315} +\setfont\ssecsl\slbshape{10}{1315} +\setfont\ssectt\ttbshape{12}{\magstephalf} +\setfont\ssecttsl\ttslshape{10}{1315} +\setfont\ssecsf\sfbshape{12}{\magstephalf} +\let\ssecbf\ssecrm +\setfont\ssecsc\scbshape{10}{1315} +\font\sseci=cmmi12 scaled \magstephalf +\font\ssecsy=cmsy10 scaled 1315 + +% Reduced fonts for @acro in text (10pt). +\def\reducednominalsize{10pt} +\setfont\reducedrm\rmshape{10}{1000} +\setfont\reducedtt\ttshape{10}{1000} +\setfont\reducedbf\bfshape{10}{1000} +\setfont\reducedit\itshape{10}{1000} +\setfont\reducedsl\slshape{10}{1000} +\setfont\reducedsf\sfshape{10}{1000} +\setfont\reducedsc\scshape{10}{1000} +\setfont\reducedttsl\ttslshape{10}{1000} +\font\reducedi=cmmi10 +\font\reducedsy=cmsy10 + +% In order for the font changes to affect most math symbols and letters, +% we have to define the \textfont of the standard families. Since +% texinfo doesn't allow for producing subscripts and superscripts except +% in the main text, we don't bother to reset \scriptfont and +% \scriptscriptfont (which would also require loading a lot more fonts). +% +\def\resetmathfonts{% + \textfont0=\tenrm \textfont1=\teni \textfont2=\tensy + \textfont\itfam=\tenit \textfont\slfam=\tensl \textfont\bffam=\tenbf + \textfont\ttfam=\tentt \textfont\sffam=\tensf +} + +% The font-changing commands redefine the meanings of \tenSTYLE, instead +% of just \STYLE. We do this because \STYLE needs to also set the +% current \fam for math mode. Our \STYLE (e.g., \rm) commands hardwire +% \tenSTYLE to set the current font. +% +% Each font-changing command also sets the names \lsize (one size lower) +% and \lllsize (three sizes lower). These relative commands are used in +% the LaTeX logo and acronyms. +% +% This all needs generalizing, badly. +% +\def\textfonts{% + \let\tenrm=\textrm \let\tenit=\textit \let\tensl=\textsl + \let\tenbf=\textbf \let\tentt=\texttt \let\smallcaps=\textsc + \let\tensf=\textsf \let\teni=\texti \let\tensy=\textsy + \let\tenttsl=\textttsl + \def\curfontsize{text}% + \def\lsize{reduced}\def\lllsize{smaller}% + \resetmathfonts \setleading{\textleading}} +\def\titlefonts{% + \let\tenrm=\titlerm \let\tenit=\titleit \let\tensl=\titlesl + \let\tenbf=\titlebf \let\tentt=\titlett \let\smallcaps=\titlesc + \let\tensf=\titlesf \let\teni=\titlei \let\tensy=\titlesy + \let\tenttsl=\titlettsl + \def\curfontsize{title}% + \def\lsize{chap}\def\lllsize{subsec}% + \resetmathfonts \setleading{25pt}} +\def\titlefont#1{{\titlefonts\rm #1}} +\def\chapfonts{% + \let\tenrm=\chaprm \let\tenit=\chapit \let\tensl=\chapsl + \let\tenbf=\chapbf \let\tentt=\chaptt \let\smallcaps=\chapsc + \let\tensf=\chapsf \let\teni=\chapi \let\tensy=\chapsy + \let\tenttsl=\chapttsl + \def\curfontsize{chap}% + \def\lsize{sec}\def\lllsize{text}% + \resetmathfonts \setleading{19pt}} +\def\secfonts{% + \let\tenrm=\secrm \let\tenit=\secit \let\tensl=\secsl + \let\tenbf=\secbf \let\tentt=\sectt \let\smallcaps=\secsc + \let\tensf=\secsf \let\teni=\seci \let\tensy=\secsy + \let\tenttsl=\secttsl + \def\curfontsize{sec}% + \def\lsize{subsec}\def\lllsize{reduced}% + \resetmathfonts \setleading{16pt}} +\def\subsecfonts{% + \let\tenrm=\ssecrm \let\tenit=\ssecit \let\tensl=\ssecsl + \let\tenbf=\ssecbf \let\tentt=\ssectt \let\smallcaps=\ssecsc + \let\tensf=\ssecsf \let\teni=\sseci \let\tensy=\ssecsy + \let\tenttsl=\ssecttsl + \def\curfontsize{ssec}% + \def\lsize{text}\def\lllsize{small}% + \resetmathfonts \setleading{15pt}} +\let\subsubsecfonts = \subsecfonts +\def\reducedfonts{% + \let\tenrm=\reducedrm \let\tenit=\reducedit \let\tensl=\reducedsl + \let\tenbf=\reducedbf \let\tentt=\reducedtt \let\reducedcaps=\reducedsc + \let\tensf=\reducedsf \let\teni=\reducedi \let\tensy=\reducedsy + \let\tenttsl=\reducedttsl + \def\curfontsize{reduced}% + \def\lsize{small}\def\lllsize{smaller}% + \resetmathfonts \setleading{10.5pt}} +\def\smallfonts{% + \let\tenrm=\smallrm \let\tenit=\smallit \let\tensl=\smallsl + \let\tenbf=\smallbf \let\tentt=\smalltt \let\smallcaps=\smallsc + \let\tensf=\smallsf \let\teni=\smalli \let\tensy=\smallsy + \let\tenttsl=\smallttsl + \def\curfontsize{small}% + \def\lsize{smaller}\def\lllsize{smaller}% + \resetmathfonts \setleading{10.5pt}} +\def\smallerfonts{% + \let\tenrm=\smallerrm \let\tenit=\smallerit \let\tensl=\smallersl + \let\tenbf=\smallerbf \let\tentt=\smallertt \let\smallcaps=\smallersc + \let\tensf=\smallersf \let\teni=\smalleri \let\tensy=\smallersy + \let\tenttsl=\smallerttsl + \def\curfontsize{smaller}% + \def\lsize{smaller}\def\lllsize{smaller}% + \resetmathfonts \setleading{9.5pt}} + +% Set the fonts to use with the @small... environments. +\let\smallexamplefonts = \smallfonts + +% About \smallexamplefonts. If we use \smallfonts (9pt), @smallexample +% can fit this many characters: +% 8.5x11=86 smallbook=72 a4=90 a5=69 +% If we use \scriptfonts (8pt), then we can fit this many characters: +% 8.5x11=90+ smallbook=80 a4=90+ a5=77 +% For me, subjectively, the few extra characters that fit aren't worth +% the additional smallness of 8pt. So I'm making the default 9pt. +% +% By the way, for comparison, here's what fits with @example (10pt): +% 8.5x11=71 smallbook=60 a4=75 a5=58 +% +% I wish the USA used A4 paper. +% --karl, 24jan03. + + +% Set up the default fonts, so we can use them for creating boxes. +% +\textfonts \rm + +% Define these so they can be easily changed for other fonts. +\def\angleleft{$\langle$} +\def\angleright{$\rangle$} + +% Count depth in font-changes, for error checks +\newcount\fontdepth \fontdepth=0 + +% Fonts for short table of contents. +\setfont\shortcontrm\rmshape{12}{1000} +\setfont\shortcontbf\bfshape{10}{\magstep1} % no cmb12 +\setfont\shortcontsl\slshape{12}{1000} +\setfont\shortconttt\ttshape{12}{1000} + +%% Add scribe-like font environments, plus @l for inline lisp (usually sans +%% serif) and @ii for TeX italic + +% \smartitalic{ARG} outputs arg in italics, followed by an italic correction +% unless the following character is such as not to need one. +\def\smartitalicx{\ifx\next,\else\ifx\next-\else\ifx\next.\else + \ptexslash\fi\fi\fi} +\def\smartslanted#1{{\ifusingtt\ttsl\sl #1}\futurelet\next\smartitalicx} +\def\smartitalic#1{{\ifusingtt\ttsl\it #1}\futurelet\next\smartitalicx} + +% like \smartslanted except unconditionally uses \ttsl. +% @var is set to this for defun arguments. +\def\ttslanted#1{{\ttsl #1}\futurelet\next\smartitalicx} + +% like \smartslanted except unconditionally use \sl. We never want +% ttsl for book titles, do we? +\def\cite#1{{\sl #1}\futurelet\next\smartitalicx} + +\let\i=\smartitalic +\let\slanted=\smartslanted +\let\var=\smartslanted +\let\dfn=\smartslanted +\let\emph=\smartitalic + +% @b, explicit bold. +\def\b#1{{\bf #1}} +\let\strong=\b + +% @sansserif, explicit sans. +\def\sansserif#1{{\sf #1}} + +% We can't just use \exhyphenpenalty, because that only has effect at +% the end of a paragraph. Restore normal hyphenation at the end of the +% group within which \nohyphenation is presumably called. +% +\def\nohyphenation{\hyphenchar\font = -1 \aftergroup\restorehyphenation} +\def\restorehyphenation{\hyphenchar\font = `- } + +% Set sfcode to normal for the chars that usually have another value. +% Can't use plain's \frenchspacing because it uses the `\x notation, and +% sometimes \x has an active definition that messes things up. +% +\catcode`@=11 + \def\frenchspacing{% + \sfcode\dotChar =\@m \sfcode\questChar=\@m \sfcode\exclamChar=\@m + \sfcode\colonChar=\@m \sfcode\semiChar =\@m \sfcode\commaChar =\@m + } +\catcode`@=\other + +\def\t#1{% + {\tt \rawbackslash \frenchspacing #1}% + \null +} +\def\samp#1{`\tclose{#1}'\null} +\setfont\keyrm\rmshape{8}{1000} +\font\keysy=cmsy9 +\def\key#1{{\keyrm\textfont2=\keysy \leavevmode\hbox{% + \raise0.4pt\hbox{\angleleft}\kern-.08em\vtop{% + \vbox{\hrule\kern-0.4pt + \hbox{\raise0.4pt\hbox{\vphantom{\angleleft}}#1}}% + \kern-0.4pt\hrule}% + \kern-.06em\raise0.4pt\hbox{\angleright}}}} +% The old definition, with no lozenge: +%\def\key #1{{\ttsl \nohyphenation \uppercase{#1}}\null} +\def\ctrl #1{{\tt \rawbackslash \hat}#1} + +% @file, @option are the same as @samp. +\let\file=\samp +\let\option=\samp + +% @code is a modification of @t, +% which makes spaces the same size as normal in the surrounding text. +\def\tclose#1{% + {% + % Change normal interword space to be same as for the current font. + \spaceskip = \fontdimen2\font + % + % Switch to typewriter. + \tt + % + % But `\ ' produces the large typewriter interword space. + \def\ {{\spaceskip = 0pt{} }}% + % + % Turn off hyphenation. + \nohyphenation + % + \rawbackslash + \frenchspacing + #1% + }% + \null +} + +% We *must* turn on hyphenation at `-' and `_' in @code. +% Otherwise, it is too hard to avoid overfull hboxes +% in the Emacs manual, the Library manual, etc. + +% Unfortunately, TeX uses one parameter (\hyphenchar) to control +% both hyphenation at - and hyphenation within words. +% We must therefore turn them both off (\tclose does that) +% and arrange explicitly to hyphenate at a dash. +% -- rms. +{ + \catcode`\-=\active + \catcode`\_=\active + % + \global\def\code{\begingroup + \catcode`\-=\active \let-\codedash + \catcode`\_=\active \let_\codeunder + \codex + } +} + +\def\realdash{-} +\def\codedash{-\discretionary{}{}{}} +\def\codeunder{% + % this is all so @math{@code{var_name}+1} can work. In math mode, _ + % is "active" (mathcode"8000) and \normalunderscore (or \char95, etc.) + % will therefore expand the active definition of _, which is us + % (inside @code that is), therefore an endless loop. + \ifusingtt{\ifmmode + \mathchar"075F % class 0=ordinary, family 7=ttfam, pos 0x5F=_. + \else\normalunderscore \fi + \discretionary{}{}{}}% + {\_}% +} +\def\codex #1{\tclose{#1}\endgroup} + +% @kbd is like @code, except that if the argument is just one @key command, +% then @kbd has no effect. + +% @kbdinputstyle -- arg is `distinct' (@kbd uses slanted tty font always), +% `example' (@kbd uses ttsl only inside of @example and friends), +% or `code' (@kbd uses normal tty font always). +\parseargdef\kbdinputstyle{% + \def\arg{#1}% + \ifx\arg\worddistinct + \gdef\kbdexamplefont{\ttsl}\gdef\kbdfont{\ttsl}% + \else\ifx\arg\wordexample + \gdef\kbdexamplefont{\ttsl}\gdef\kbdfont{\tt}% + \else\ifx\arg\wordcode + \gdef\kbdexamplefont{\tt}\gdef\kbdfont{\tt}% + \else + \errhelp = \EMsimple + \errmessage{Unknown @kbdinputstyle option `\arg'}% + \fi\fi\fi +} +\def\worddistinct{distinct} +\def\wordexample{example} +\def\wordcode{code} + +% Default is `distinct.' +\kbdinputstyle distinct + +\def\xkey{\key} +\def\kbdfoo#1#2#3\par{\def\one{#1}\def\three{#3}\def\threex{??}% +\ifx\one\xkey\ifx\threex\three \key{#2}% +\else{\tclose{\kbdfont\look}}\fi +\else{\tclose{\kbdfont\look}}\fi} + +% For @indicateurl, @env, @command quotes seem unnecessary, so use \code. +\let\indicateurl=\code +\let\env=\code +\let\command=\code + +% @uref (abbreviation for `urlref') takes an optional (comma-separated) +% second argument specifying the text to display and an optional third +% arg as text to display instead of (rather than in addition to) the url +% itself. First (mandatory) arg is the url. Perhaps eventually put in +% a hypertex \special here. +% +\def\uref#1{\douref #1,,,\finish} +\def\douref#1,#2,#3,#4\finish{\begingroup + \unsepspaces + \pdfurl{#1}% + \setbox0 = \hbox{\ignorespaces #3}% + \ifdim\wd0 > 0pt + \unhbox0 % third arg given, show only that + \else + \setbox0 = \hbox{\ignorespaces #2}% + \ifdim\wd0 > 0pt + \ifpdf + \unhbox0 % PDF: 2nd arg given, show only it + \else + \unhbox0\ (\code{#1})% DVI: 2nd arg given, show both it and url + \fi + \else + \code{#1}% only url given, so show it + \fi + \fi + \endlink +\endgroup} + +% @url synonym for @uref, since that's how everyone uses it. +% +\let\url=\uref + +% rms does not like angle brackets --karl, 17may97. +% So now @email is just like @uref, unless we are pdf. +% +%\def\email#1{\angleleft{\tt #1}\angleright} +\ifpdf + \def\email#1{\doemail#1,,\finish} + \def\doemail#1,#2,#3\finish{\begingroup + \unsepspaces + \pdfurl{mailto:#1}% + \setbox0 = \hbox{\ignorespaces #2}% + \ifdim\wd0>0pt\unhbox0\else\code{#1}\fi + \endlink + \endgroup} +\else + \let\email=\uref +\fi + +% Check if we are currently using a typewriter font. Since all the +% Computer Modern typewriter fonts have zero interword stretch (and +% shrink), and it is reasonable to expect all typewriter fonts to have +% this property, we can check that font parameter. +% +\def\ifmonospace{\ifdim\fontdimen3\font=0pt } + +% Typeset a dimension, e.g., `in' or `pt'. The only reason for the +% argument is to make the input look right: @dmn{pt} instead of @dmn{}pt. +% +\def\dmn#1{\thinspace #1} + +\def\kbd#1{\def\look{#1}\expandafter\kbdfoo\look??\par} + +% @l was never documented to mean ``switch to the Lisp font'', +% and it is not used as such in any manual I can find. We need it for +% Polish suppressed-l. --karl, 22sep96. +%\def\l#1{{\li #1}\null} + +% Explicit font changes: @r, @sc, undocumented @ii. +\def\r#1{{\rm #1}} % roman font +\def\sc#1{{\smallcaps#1}} % smallcaps font +\def\ii#1{{\it #1}} % italic font + +% @acronym for "FBI", "NATO", and the like. +% We print this one point size smaller, since it's intended for +% all-uppercase. +% +\def\acronym#1{\doacronym #1,,\finish} +\def\doacronym#1,#2,#3\finish{% + {\selectfonts\lsize #1}% + \def\temp{#2}% + \ifx\temp\empty \else + \space ({\unsepspaces \ignorespaces \temp \unskip})% + \fi +} + +% @abbr for "Comput. J." and the like. +% No font change, but don't do end-of-sentence spacing. +% +\def\abbr#1{\doabbr #1,,\finish} +\def\doabbr#1,#2,#3\finish{% + {\frenchspacing #1}% + \def\temp{#2}% + \ifx\temp\empty \else + \space ({\unsepspaces \ignorespaces \temp \unskip})% + \fi +} + +% @pounds{} is a sterling sign, which Knuth put in the CM italic font. +% +\def\pounds{{\it\$}} + +% @euro{} comes from a separate font, depending on the current style. +% We use the free feym* fonts from the eurosym package by Henrik +% Theiling, which support regular, slanted, bold and bold slanted (and +% "outlined" (blackboard board, sort of) versions, which we don't need). +% It is available from http://www.ctan.org/tex-archive/fonts/eurosym. +% +% Although only regular is the truly official Euro symbol, we ignore +% that. The Euro is designed to be slightly taller than the regular +% font height. +% +% feymr - regular +% feymo - slanted +% feybr - bold +% feybo - bold slanted +% +% There is no good (free) typewriter version, to my knowledge. +% A feymr10 euro is ~7.3pt wide, while a normal cmtt10 char is ~5.25pt wide. +% Hmm. +% +% Also doesn't work in math. Do we need to do math with euro symbols? +% Hope not. +% +% +\def\euro{{\eurofont e}} +\def\eurofont{% + % We set the font at each command, rather than predefining it in + % \textfonts and the other font-switching commands, so that + % installations which never need the symbol don't have to have the + % font installed. + % + % There is only one designed size (nominal 10pt), so we always scale + % that to the current nominal size. + % + % By the way, simply using "at 1em" works for cmr10 and the like, but + % does not work for cmbx10 and other extended/shrunken fonts. + % + \def\eurosize{\csname\curfontsize nominalsize\endcsname}% + % + \ifx\curfontstyle\bfstylename + % bold: + \font\thiseurofont = \ifusingit{feybo10}{feybr10} at \eurosize + \else + % regular: + \font\thiseurofont = \ifusingit{feymo10}{feymr10} at \eurosize + \fi + \thiseurofont +} + +% @registeredsymbol - R in a circle. The font for the R should really +% be smaller yet, but lllsize is the best we can do for now. +% Adapted from the plain.tex definition of \copyright. +% +\def\registeredsymbol{% + $^{{\ooalign{\hfil\raise.07ex\hbox{\selectfonts\lllsize R}% + \hfil\crcr\Orb}}% + }$% +} + +% Laurent Siebenmann reports \Orb undefined with: +% Textures 1.7.7 (preloaded format=plain 93.10.14) (68K) 16 APR 2004 02:38 +% so we'll define it if necessary. +% +\ifx\Orb\undefined +\def\Orb{\mathhexbox20D} +\fi + + +\message{page headings,} + +\newskip\titlepagetopglue \titlepagetopglue = 1.5in +\newskip\titlepagebottomglue \titlepagebottomglue = 2pc + +% First the title page. Must do @settitle before @titlepage. +\newif\ifseenauthor +\newif\iffinishedtitlepage + +% Do an implicit @contents or @shortcontents after @end titlepage if the +% user says @setcontentsaftertitlepage or @setshortcontentsaftertitlepage. +% +\newif\ifsetcontentsaftertitlepage + \let\setcontentsaftertitlepage = \setcontentsaftertitlepagetrue +\newif\ifsetshortcontentsaftertitlepage + \let\setshortcontentsaftertitlepage = \setshortcontentsaftertitlepagetrue + +\parseargdef\shorttitlepage{\begingroup\hbox{}\vskip 1.5in \chaprm \centerline{#1}% + \endgroup\page\hbox{}\page} + +\envdef\titlepage{% + % Open one extra group, as we want to close it in the middle of \Etitlepage. + \begingroup + \parindent=0pt \textfonts + % Leave some space at the very top of the page. + \vglue\titlepagetopglue + % No rule at page bottom unless we print one at the top with @title. + \finishedtitlepagetrue + % + % Most title ``pages'' are actually two pages long, with space + % at the top of the second. We don't want the ragged left on the second. + \let\oldpage = \page + \def\page{% + \iffinishedtitlepage\else + \finishtitlepage + \fi + \let\page = \oldpage + \page + \null + }% +} + +\def\Etitlepage{% + \iffinishedtitlepage\else + \finishtitlepage + \fi + % It is important to do the page break before ending the group, + % because the headline and footline are only empty inside the group. + % If we use the new definition of \page, we always get a blank page + % after the title page, which we certainly don't want. + \oldpage + \endgroup + % + % Need this before the \...aftertitlepage checks so that if they are + % in effect the toc pages will come out with page numbers. + \HEADINGSon + % + % If they want short, they certainly want long too. + \ifsetshortcontentsaftertitlepage + \shortcontents + \contents + \global\let\shortcontents = \relax + \global\let\contents = \relax + \fi + % + \ifsetcontentsaftertitlepage + \contents + \global\let\contents = \relax + \global\let\shortcontents = \relax + \fi +} + +\def\finishtitlepage{% + \vskip4pt \hrule height 2pt width \hsize + \vskip\titlepagebottomglue + \finishedtitlepagetrue +} + +%%% Macros to be used within @titlepage: + +\let\subtitlerm=\tenrm +\def\subtitlefont{\subtitlerm \normalbaselineskip = 13pt \normalbaselines} + +\def\authorfont{\authorrm \normalbaselineskip = 16pt \normalbaselines + \let\tt=\authortt} + +\parseargdef\title{% + \checkenv\titlepage + \leftline{\titlefonts\rm #1} + % print a rule at the page bottom also. + \finishedtitlepagefalse + \vskip4pt \hrule height 4pt width \hsize \vskip4pt +} + +\parseargdef\subtitle{% + \checkenv\titlepage + {\subtitlefont \rightline{#1}}% +} + +% @author should come last, but may come many times. +% It can also be used inside @quotation. +% +\parseargdef\author{% + \def\temp{\quotation}% + \ifx\thisenv\temp + \def\quotationauthor{#1}% printed in \Equotation. + \else + \checkenv\titlepage + \ifseenauthor\else \vskip 0pt plus 1filll \seenauthortrue \fi + {\authorfont \leftline{#1}}% + \fi +} + + +%%% Set up page headings and footings. + +\let\thispage=\folio + +\newtoks\evenheadline % headline on even pages +\newtoks\oddheadline % headline on odd pages +\newtoks\evenfootline % footline on even pages +\newtoks\oddfootline % footline on odd pages + +% Now make TeX use those variables +\headline={{\textfonts\rm \ifodd\pageno \the\oddheadline + \else \the\evenheadline \fi}} +\footline={{\textfonts\rm \ifodd\pageno \the\oddfootline + \else \the\evenfootline \fi}\HEADINGShook} +\let\HEADINGShook=\relax + +% Commands to set those variables. +% For example, this is what @headings on does +% @evenheading @thistitle|@thispage|@thischapter +% @oddheading @thischapter|@thispage|@thistitle +% @evenfooting @thisfile|| +% @oddfooting ||@thisfile + + +\def\evenheading{\parsearg\evenheadingxxx} +\def\evenheadingxxx #1{\evenheadingyyy #1\|\|\|\|\finish} +\def\evenheadingyyy #1\|#2\|#3\|#4\finish{% +\global\evenheadline={\rlap{\centerline{#2}}\line{#1\hfil#3}}} + +\def\oddheading{\parsearg\oddheadingxxx} +\def\oddheadingxxx #1{\oddheadingyyy #1\|\|\|\|\finish} +\def\oddheadingyyy #1\|#2\|#3\|#4\finish{% +\global\oddheadline={\rlap{\centerline{#2}}\line{#1\hfil#3}}} + +\parseargdef\everyheading{\oddheadingxxx{#1}\evenheadingxxx{#1}}% + +\def\evenfooting{\parsearg\evenfootingxxx} +\def\evenfootingxxx #1{\evenfootingyyy #1\|\|\|\|\finish} +\def\evenfootingyyy #1\|#2\|#3\|#4\finish{% +\global\evenfootline={\rlap{\centerline{#2}}\line{#1\hfil#3}}} + +\def\oddfooting{\parsearg\oddfootingxxx} +\def\oddfootingxxx #1{\oddfootingyyy #1\|\|\|\|\finish} +\def\oddfootingyyy #1\|#2\|#3\|#4\finish{% + \global\oddfootline = {\rlap{\centerline{#2}}\line{#1\hfil#3}}% + % + % Leave some space for the footline. Hopefully ok to assume + % @evenfooting will not be used by itself. + \global\advance\pageheight by -\baselineskip + \global\advance\vsize by -\baselineskip +} + +\parseargdef\everyfooting{\oddfootingxxx{#1}\evenfootingxxx{#1}} + + +% @headings double turns headings on for double-sided printing. +% @headings single turns headings on for single-sided printing. +% @headings off turns them off. +% @headings on same as @headings double, retained for compatibility. +% @headings after turns on double-sided headings after this page. +% @headings doubleafter turns on double-sided headings after this page. +% @headings singleafter turns on single-sided headings after this page. +% By default, they are off at the start of a document, +% and turned `on' after @end titlepage. + +\def\headings #1 {\csname HEADINGS#1\endcsname} + +\def\HEADINGSoff{% +\global\evenheadline={\hfil} \global\evenfootline={\hfil} +\global\oddheadline={\hfil} \global\oddfootline={\hfil}} +\HEADINGSoff +% When we turn headings on, set the page number to 1. +% For double-sided printing, put current file name in lower left corner, +% chapter name on inside top of right hand pages, document +% title on inside top of left hand pages, and page numbers on outside top +% edge of all pages. +\def\HEADINGSdouble{% +\global\pageno=1 +\global\evenfootline={\hfil} +\global\oddfootline={\hfil} +\global\evenheadline={\line{\folio\hfil\thistitle}} +\global\oddheadline={\line{\thischapter\hfil\folio}} +\global\let\contentsalignmacro = \chapoddpage +} +\let\contentsalignmacro = \chappager + +% For single-sided printing, chapter title goes across top left of page, +% page number on top right. +\def\HEADINGSsingle{% +\global\pageno=1 +\global\evenfootline={\hfil} +\global\oddfootline={\hfil} +\global\evenheadline={\line{\thischapter\hfil\folio}} +\global\oddheadline={\line{\thischapter\hfil\folio}} +\global\let\contentsalignmacro = \chappager +} +\def\HEADINGSon{\HEADINGSdouble} + +\def\HEADINGSafter{\let\HEADINGShook=\HEADINGSdoublex} +\let\HEADINGSdoubleafter=\HEADINGSafter +\def\HEADINGSdoublex{% +\global\evenfootline={\hfil} +\global\oddfootline={\hfil} +\global\evenheadline={\line{\folio\hfil\thistitle}} +\global\oddheadline={\line{\thischapter\hfil\folio}} +\global\let\contentsalignmacro = \chapoddpage +} + +\def\HEADINGSsingleafter{\let\HEADINGShook=\HEADINGSsinglex} +\def\HEADINGSsinglex{% +\global\evenfootline={\hfil} +\global\oddfootline={\hfil} +\global\evenheadline={\line{\thischapter\hfil\folio}} +\global\oddheadline={\line{\thischapter\hfil\folio}} +\global\let\contentsalignmacro = \chappager +} + +% Subroutines used in generating headings +% This produces Day Month Year style of output. +% Only define if not already defined, in case a txi-??.tex file has set +% up a different format (e.g., txi-cs.tex does this). +\ifx\today\undefined +\def\today{% + \number\day\space + \ifcase\month + \or\putwordMJan\or\putwordMFeb\or\putwordMMar\or\putwordMApr + \or\putwordMMay\or\putwordMJun\or\putwordMJul\or\putwordMAug + \or\putwordMSep\or\putwordMOct\or\putwordMNov\or\putwordMDec + \fi + \space\number\year} +\fi + +% @settitle line... specifies the title of the document, for headings. +% It generates no output of its own. +\def\thistitle{\putwordNoTitle} +\def\settitle{\parsearg{\gdef\thistitle}} + + +\message{tables,} +% Tables -- @table, @ftable, @vtable, @item(x). + +% default indentation of table text +\newdimen\tableindent \tableindent=.8in +% default indentation of @itemize and @enumerate text +\newdimen\itemindent \itemindent=.3in +% margin between end of table item and start of table text. +\newdimen\itemmargin \itemmargin=.1in + +% used internally for \itemindent minus \itemmargin +\newdimen\itemmax + +% Note @table, @ftable, and @vtable define @item, @itemx, etc., with +% these defs. +% They also define \itemindex +% to index the item name in whatever manner is desired (perhaps none). + +\newif\ifitemxneedsnegativevskip + +\def\itemxpar{\par\ifitemxneedsnegativevskip\nobreak\vskip-\parskip\nobreak\fi} + +\def\internalBitem{\smallbreak \parsearg\itemzzz} +\def\internalBitemx{\itemxpar \parsearg\itemzzz} + +\def\itemzzz #1{\begingroup % + \advance\hsize by -\rightskip + \advance\hsize by -\tableindent + \setbox0=\hbox{\itemindicate{#1}}% + \itemindex{#1}% + \nobreak % This prevents a break before @itemx. + % + % If the item text does not fit in the space we have, put it on a line + % by itself, and do not allow a page break either before or after that + % line. We do not start a paragraph here because then if the next + % command is, e.g., @kindex, the whatsit would get put into the + % horizontal list on a line by itself, resulting in extra blank space. + \ifdim \wd0>\itemmax + % + % Make this a paragraph so we get the \parskip glue and wrapping, + % but leave it ragged-right. + \begingroup + \advance\leftskip by-\tableindent + \advance\hsize by\tableindent + \advance\rightskip by0pt plus1fil + \leavevmode\unhbox0\par + \endgroup + % + % We're going to be starting a paragraph, but we don't want the + % \parskip glue -- logically it's part of the @item we just started. + \nobreak \vskip-\parskip + % + % Stop a page break at the \parskip glue coming up. However, if + % what follows is an environment such as @example, there will be no + % \parskip glue; then the negative vskip we just inserted would + % cause the example and the item to crash together. So we use this + % bizarre value of 10001 as a signal to \aboveenvbreak to insert + % \parskip glue after all. Section titles are handled this way also. + % + \penalty 10001 + \endgroup + \itemxneedsnegativevskipfalse + \else + % The item text fits into the space. Start a paragraph, so that the + % following text (if any) will end up on the same line. + \noindent + % Do this with kerns and \unhbox so that if there is a footnote in + % the item text, it can migrate to the main vertical list and + % eventually be printed. + \nobreak\kern-\tableindent + \dimen0 = \itemmax \advance\dimen0 by \itemmargin \advance\dimen0 by -\wd0 + \unhbox0 + \nobreak\kern\dimen0 + \endgroup + \itemxneedsnegativevskiptrue + \fi +} + +\def\item{\errmessage{@item while not in a list environment}} +\def\itemx{\errmessage{@itemx while not in a list environment}} + +% @table, @ftable, @vtable. +\envdef\table{% + \let\itemindex\gobble + \tablecheck{table}% +} +\envdef\ftable{% + \def\itemindex ##1{\doind {fn}{\code{##1}}}% + \tablecheck{ftable}% +} +\envdef\vtable{% + \def\itemindex ##1{\doind {vr}{\code{##1}}}% + \tablecheck{vtable}% +} +\def\tablecheck#1{% + \ifnum \the\catcode`\^^M=\active + \endgroup + \errmessage{This command won't work in this context; perhaps the problem is + that we are \inenvironment\thisenv}% + \def\next{\doignore{#1}}% + \else + \let\next\tablex + \fi + \next +} +\def\tablex#1{% + \def\itemindicate{#1}% + \parsearg\tabley +} +\def\tabley#1{% + {% + \makevalueexpandable + \edef\temp{\noexpand\tablez #1\space\space\space}% + \expandafter + }\temp \endtablez +} +\def\tablez #1 #2 #3 #4\endtablez{% + \aboveenvbreak + \ifnum 0#1>0 \advance \leftskip by #1\mil \fi + \ifnum 0#2>0 \tableindent=#2\mil \fi + \ifnum 0#3>0 \advance \rightskip by #3\mil \fi + \itemmax=\tableindent + \advance \itemmax by -\itemmargin + \advance \leftskip by \tableindent + \exdentamount=\tableindent + \parindent = 0pt + \parskip = \smallskipamount + \ifdim \parskip=0pt \parskip=2pt \fi + \let\item = \internalBitem + \let\itemx = \internalBitemx +} +\def\Etable{\endgraf\afterenvbreak} +\let\Eftable\Etable +\let\Evtable\Etable +\let\Eitemize\Etable +\let\Eenumerate\Etable + +% This is the counter used by @enumerate, which is really @itemize + +\newcount \itemno + +\envdef\itemize{\parsearg\doitemize} + +\def\doitemize#1{% + \aboveenvbreak + \itemmax=\itemindent + \advance\itemmax by -\itemmargin + \advance\leftskip by \itemindent + \exdentamount=\itemindent + \parindent=0pt + \parskip=\smallskipamount + \ifdim\parskip=0pt \parskip=2pt \fi + \def\itemcontents{#1}% + % @itemize with no arg is equivalent to @itemize @bullet. + \ifx\itemcontents\empty\def\itemcontents{\bullet}\fi + \let\item=\itemizeitem +} + +% Definition of @item while inside @itemize and @enumerate. +% +\def\itemizeitem{% + \advance\itemno by 1 % for enumerations + {\let\par=\endgraf \smallbreak}% reasonable place to break + {% + % If the document has an @itemize directly after a section title, a + % \nobreak will be last on the list, and \sectionheading will have + % done a \vskip-\parskip. In that case, we don't want to zero + % parskip, or the item text will crash with the heading. On the + % other hand, when there is normal text preceding the item (as there + % usually is), we do want to zero parskip, or there would be too much + % space. In that case, we won't have a \nobreak before. At least + % that's the theory. + \ifnum\lastpenalty<10000 \parskip=0in \fi + \noindent + \hbox to 0pt{\hss \itemcontents \kern\itemmargin}% + \vadjust{\penalty 1200}}% not good to break after first line of item. + \flushcr +} + +% \splitoff TOKENS\endmark defines \first to be the first token in +% TOKENS, and \rest to be the remainder. +% +\def\splitoff#1#2\endmark{\def\first{#1}\def\rest{#2}}% + +% Allow an optional argument of an uppercase letter, lowercase letter, +% or number, to specify the first label in the enumerated list. No +% argument is the same as `1'. +% +\envparseargdef\enumerate{\enumeratey #1 \endenumeratey} +\def\enumeratey #1 #2\endenumeratey{% + % If we were given no argument, pretend we were given `1'. + \def\thearg{#1}% + \ifx\thearg\empty \def\thearg{1}\fi + % + % Detect if the argument is a single token. If so, it might be a + % letter. Otherwise, the only valid thing it can be is a number. + % (We will always have one token, because of the test we just made. + % This is a good thing, since \splitoff doesn't work given nothing at + % all -- the first parameter is undelimited.) + \expandafter\splitoff\thearg\endmark + \ifx\rest\empty + % Only one token in the argument. It could still be anything. + % A ``lowercase letter'' is one whose \lccode is nonzero. + % An ``uppercase letter'' is one whose \lccode is both nonzero, and + % not equal to itself. + % Otherwise, we assume it's a number. + % + % We need the \relax at the end of the \ifnum lines to stop TeX from + % continuing to look for a . + % + \ifnum\lccode\expandafter`\thearg=0\relax + \numericenumerate % a number (we hope) + \else + % It's a letter. + \ifnum\lccode\expandafter`\thearg=\expandafter`\thearg\relax + \lowercaseenumerate % lowercase letter + \else + \uppercaseenumerate % uppercase letter + \fi + \fi + \else + % Multiple tokens in the argument. We hope it's a number. + \numericenumerate + \fi +} + +% An @enumerate whose labels are integers. The starting integer is +% given in \thearg. +% +\def\numericenumerate{% + \itemno = \thearg + \startenumeration{\the\itemno}% +} + +% The starting (lowercase) letter is in \thearg. +\def\lowercaseenumerate{% + \itemno = \expandafter`\thearg + \startenumeration{% + % Be sure we're not beyond the end of the alphabet. + \ifnum\itemno=0 + \errmessage{No more lowercase letters in @enumerate; get a bigger + alphabet}% + \fi + \char\lccode\itemno + }% +} + +% The starting (uppercase) letter is in \thearg. +\def\uppercaseenumerate{% + \itemno = \expandafter`\thearg + \startenumeration{% + % Be sure we're not beyond the end of the alphabet. + \ifnum\itemno=0 + \errmessage{No more uppercase letters in @enumerate; get a bigger + alphabet} + \fi + \char\uccode\itemno + }% +} + +% Call \doitemize, adding a period to the first argument and supplying the +% common last two arguments. Also subtract one from the initial value in +% \itemno, since @item increments \itemno. +% +\def\startenumeration#1{% + \advance\itemno by -1 + \doitemize{#1.}\flushcr +} + +% @alphaenumerate and @capsenumerate are abbreviations for giving an arg +% to @enumerate. +% +\def\alphaenumerate{\enumerate{a}} +\def\capsenumerate{\enumerate{A}} +\def\Ealphaenumerate{\Eenumerate} +\def\Ecapsenumerate{\Eenumerate} + + +% @multitable macros +% Amy Hendrickson, 8/18/94, 3/6/96 +% +% @multitable ... @end multitable will make as many columns as desired. +% Contents of each column will wrap at width given in preamble. Width +% can be specified either with sample text given in a template line, +% or in percent of \hsize, the current width of text on page. + +% Table can continue over pages but will only break between lines. + +% To make preamble: +% +% Either define widths of columns in terms of percent of \hsize: +% @multitable @columnfractions .25 .3 .45 +% @item ... +% +% Numbers following @columnfractions are the percent of the total +% current hsize to be used for each column. You may use as many +% columns as desired. + + +% Or use a template: +% @multitable {Column 1 template} {Column 2 template} {Column 3 template} +% @item ... +% using the widest term desired in each column. + +% Each new table line starts with @item, each subsequent new column +% starts with @tab. Empty columns may be produced by supplying @tab's +% with nothing between them for as many times as empty columns are needed, +% ie, @tab@tab@tab will produce two empty columns. + +% @item, @tab do not need to be on their own lines, but it will not hurt +% if they are. + +% Sample multitable: + +% @multitable {Column 1 template} {Column 2 template} {Column 3 template} +% @item first col stuff @tab second col stuff @tab third col +% @item +% first col stuff +% @tab +% second col stuff +% @tab +% third col +% @item first col stuff @tab second col stuff +% @tab Many paragraphs of text may be used in any column. +% +% They will wrap at the width determined by the template. +% @item@tab@tab This will be in third column. +% @end multitable + +% Default dimensions may be reset by user. +% @multitableparskip is vertical space between paragraphs in table. +% @multitableparindent is paragraph indent in table. +% @multitablecolmargin is horizontal space to be left between columns. +% @multitablelinespace is space to leave between table items, baseline +% to baseline. +% 0pt means it depends on current normal line spacing. +% +\newskip\multitableparskip +\newskip\multitableparindent +\newdimen\multitablecolspace +\newskip\multitablelinespace +\multitableparskip=0pt +\multitableparindent=6pt +\multitablecolspace=12pt +\multitablelinespace=0pt + +% Macros used to set up halign preamble: +% +\let\endsetuptable\relax +\def\xendsetuptable{\endsetuptable} +\let\columnfractions\relax +\def\xcolumnfractions{\columnfractions} +\newif\ifsetpercent + +% #1 is the @columnfraction, usually a decimal number like .5, but might +% be just 1. We just use it, whatever it is. +% +\def\pickupwholefraction#1 {% + \global\advance\colcount by 1 + \expandafter\xdef\csname col\the\colcount\endcsname{#1\hsize}% + \setuptable +} + +\newcount\colcount +\def\setuptable#1{% + \def\firstarg{#1}% + \ifx\firstarg\xendsetuptable + \let\go = \relax + \else + \ifx\firstarg\xcolumnfractions + \global\setpercenttrue + \else + \ifsetpercent + \let\go\pickupwholefraction + \else + \global\advance\colcount by 1 + \setbox0=\hbox{#1\unskip\space}% Add a normal word space as a + % separator; typically that is always in the input, anyway. + \expandafter\xdef\csname col\the\colcount\endcsname{\the\wd0}% + \fi + \fi + \ifx\go\pickupwholefraction + % Put the argument back for the \pickupwholefraction call, so + % we'll always have a period there to be parsed. + \def\go{\pickupwholefraction#1}% + \else + \let\go = \setuptable + \fi% + \fi + \go +} + +% multitable-only commands. +% +% @headitem starts a heading row, which we typeset in bold. +% Assignments have to be global since we are inside the implicit group +% of an alignment entry. Note that \everycr resets \everytab. +\def\headitem{\checkenv\multitable \crcr \global\everytab={\bf}\the\everytab}% +% +% A \tab used to include \hskip1sp. But then the space in a template +% line is not enough. That is bad. So let's go back to just `&' until +% we encounter the problem it was intended to solve again. +% --karl, nathan@acm.org, 20apr99. +\def\tab{\checkenv\multitable &\the\everytab}% + +% @multitable ... @end multitable definitions: +% +\newtoks\everytab % insert after every tab. +% +\envdef\multitable{% + \vskip\parskip + \startsavinginserts + % + % @item within a multitable starts a normal row. + % We use \def instead of \let so that if one of the multitable entries + % contains an @itemize, we don't choke on the \item (seen as \crcr aka + % \endtemplate) expanding \doitemize. + \def\item{\crcr}% + % + \tolerance=9500 + \hbadness=9500 + \setmultitablespacing + \parskip=\multitableparskip + \parindent=\multitableparindent + \overfullrule=0pt + \global\colcount=0 + % + \everycr = {% + \noalign{% + \global\everytab={}% + \global\colcount=0 % Reset the column counter. + % Check for saved footnotes, etc. + \checkinserts + % Keeps underfull box messages off when table breaks over pages. + %\filbreak + % Maybe so, but it also creates really weird page breaks when the + % table breaks over pages. Wouldn't \vfil be better? Wait until the + % problem manifests itself, so it can be fixed for real --karl. + }% + }% + % + \parsearg\domultitable +} +\def\domultitable#1{% + % To parse everything between @multitable and @item: + \setuptable#1 \endsetuptable + % + % This preamble sets up a generic column definition, which will + % be used as many times as user calls for columns. + % \vtop will set a single line and will also let text wrap and + % continue for many paragraphs if desired. + \halign\bgroup &% + \global\advance\colcount by 1 + \multistrut + \vtop{% + % Use the current \colcount to find the correct column width: + \hsize=\expandafter\csname col\the\colcount\endcsname + % + % In order to keep entries from bumping into each other + % we will add a \leftskip of \multitablecolspace to all columns after + % the first one. + % + % If a template has been used, we will add \multitablecolspace + % to the width of each template entry. + % + % If the user has set preamble in terms of percent of \hsize we will + % use that dimension as the width of the column, and the \leftskip + % will keep entries from bumping into each other. Table will start at + % left margin and final column will justify at right margin. + % + % Make sure we don't inherit \rightskip from the outer environment. + \rightskip=0pt + \ifnum\colcount=1 + % The first column will be indented with the surrounding text. + \advance\hsize by\leftskip + \else + \ifsetpercent \else + % If user has not set preamble in terms of percent of \hsize + % we will advance \hsize by \multitablecolspace. + \advance\hsize by \multitablecolspace + \fi + % In either case we will make \leftskip=\multitablecolspace: + \leftskip=\multitablecolspace + \fi + % Ignoring space at the beginning and end avoids an occasional spurious + % blank line, when TeX decides to break the line at the space before the + % box from the multistrut, so the strut ends up on a line by itself. + % For example: + % @multitable @columnfractions .11 .89 + % @item @code{#} + % @tab Legal holiday which is valid in major parts of the whole country. + % Is automatically provided with highlighting sequences respectively + % marking characters. + \noindent\ignorespaces##\unskip\multistrut + }\cr +} +\def\Emultitable{% + \crcr + \egroup % end the \halign + \global\setpercentfalse +} + +\def\setmultitablespacing{% + \def\multistrut{\strut}% just use the standard line spacing + % + % Compute \multitablelinespace (if not defined by user) for use in + % \multitableparskip calculation. We used define \multistrut based on + % this, but (ironically) that caused the spacing to be off. + % See bug-texinfo report from Werner Lemberg, 31 Oct 2004 12:52:20 +0100. +\ifdim\multitablelinespace=0pt +\setbox0=\vbox{X}\global\multitablelinespace=\the\baselineskip +\global\advance\multitablelinespace by-\ht0 +\fi +%% Test to see if parskip is larger than space between lines of +%% table. If not, do nothing. +%% If so, set to same dimension as multitablelinespace. +\ifdim\multitableparskip>\multitablelinespace +\global\multitableparskip=\multitablelinespace +\global\advance\multitableparskip-7pt %% to keep parskip somewhat smaller + %% than skip between lines in the table. +\fi% +\ifdim\multitableparskip=0pt +\global\multitableparskip=\multitablelinespace +\global\advance\multitableparskip-7pt %% to keep parskip somewhat smaller + %% than skip between lines in the table. +\fi} + + +\message{conditionals,} + +% @iftex, @ifnotdocbook, @ifnothtml, @ifnotinfo, @ifnotplaintext, +% @ifnotxml always succeed. They currently do nothing; we don't +% attempt to check whether the conditionals are properly nested. But we +% have to remember that they are conditionals, so that @end doesn't +% attempt to close an environment group. +% +\def\makecond#1{% + \expandafter\let\csname #1\endcsname = \relax + \expandafter\let\csname iscond.#1\endcsname = 1 +} +\makecond{iftex} +\makecond{ifnotdocbook} +\makecond{ifnothtml} +\makecond{ifnotinfo} +\makecond{ifnotplaintext} +\makecond{ifnotxml} + +% Ignore @ignore, @ifhtml, @ifinfo, and the like. +% +\def\direntry{\doignore{direntry}} +\def\documentdescription{\doignore{documentdescription}} +\def\docbook{\doignore{docbook}} +\def\html{\doignore{html}} +\def\ifdocbook{\doignore{ifdocbook}} +\def\ifhtml{\doignore{ifhtml}} +\def\ifinfo{\doignore{ifinfo}} +\def\ifnottex{\doignore{ifnottex}} +\def\ifplaintext{\doignore{ifplaintext}} +\def\ifxml{\doignore{ifxml}} +\def\ignore{\doignore{ignore}} +\def\menu{\doignore{menu}} +\def\xml{\doignore{xml}} + +% Ignore text until a line `@end #1', keeping track of nested conditionals. +% +% A count to remember the depth of nesting. +\newcount\doignorecount + +\def\doignore#1{\begingroup + % Scan in ``verbatim'' mode: + \catcode`\@ = \other + \catcode`\{ = \other + \catcode`\} = \other + % + % Make sure that spaces turn into tokens that match what \doignoretext wants. + \spaceisspace + % + % Count number of #1's that we've seen. + \doignorecount = 0 + % + % Swallow text until we reach the matching `@end #1'. + \dodoignore{#1}% +} + +{ \catcode`_=11 % We want to use \_STOP_ which cannot appear in texinfo source. + \obeylines % + % + \gdef\dodoignore#1{% + % #1 contains the command name as a string, e.g., `ifinfo'. + % + % Define a command to find the next `@end #1', which must be on a line + % by itself. + \long\def\doignoretext##1^^M@end #1{\doignoretextyyy##1^^M@#1\_STOP_}% + % And this command to find another #1 command, at the beginning of a + % line. (Otherwise, we would consider a line `@c @ifset', for + % example, to count as an @ifset for nesting.) + \long\def\doignoretextyyy##1^^M@#1##2\_STOP_{\doignoreyyy{##2}\_STOP_}% + % + % And now expand that command. + \obeylines % + \doignoretext ^^M% + }% +} + +\def\doignoreyyy#1{% + \def\temp{#1}% + \ifx\temp\empty % Nothing found. + \let\next\doignoretextzzz + \else % Found a nested condition, ... + \advance\doignorecount by 1 + \let\next\doignoretextyyy % ..., look for another. + % If we're here, #1 ends with ^^M\ifinfo (for example). + \fi + \next #1% the token \_STOP_ is present just after this macro. +} + +% We have to swallow the remaining "\_STOP_". +% +\def\doignoretextzzz#1{% + \ifnum\doignorecount = 0 % We have just found the outermost @end. + \let\next\enddoignore + \else % Still inside a nested condition. + \advance\doignorecount by -1 + \let\next\doignoretext % Look for the next @end. + \fi + \next +} + +% Finish off ignored text. +\def\enddoignore{\endgroup\ignorespaces} + + +% @set VAR sets the variable VAR to an empty value. +% @set VAR REST-OF-LINE sets VAR to the value REST-OF-LINE. +% +% Since we want to separate VAR from REST-OF-LINE (which might be +% empty), we can't just use \parsearg; we have to insert a space of our +% own to delimit the rest of the line, and then take it out again if we +% didn't need it. +% We rely on the fact that \parsearg sets \catcode`\ =10. +% +\parseargdef\set{\setyyy#1 \endsetyyy} +\def\setyyy#1 #2\endsetyyy{% + {% + \makevalueexpandable + \def\temp{#2}% + \edef\next{\gdef\makecsname{SET#1}}% + \ifx\temp\empty + \next{}% + \else + \setzzz#2\endsetzzz + \fi + }% +} +% Remove the trailing space \setxxx inserted. +\def\setzzz#1 \endsetzzz{\next{#1}} + +% @clear VAR clears (i.e., unsets) the variable VAR. +% +\parseargdef\clear{% + {% + \makevalueexpandable + \global\expandafter\let\csname SET#1\endcsname=\relax + }% +} + +% @value{foo} gets the text saved in variable foo. +\def\value{\begingroup\makevalueexpandable\valuexxx} +\def\valuexxx#1{\expandablevalue{#1}\endgroup} +{ + \catcode`\- = \active \catcode`\_ = \active + % + \gdef\makevalueexpandable{% + \let\value = \expandablevalue + % We don't want these characters active, ... + \catcode`\-=\other \catcode`\_=\other + % ..., but we might end up with active ones in the argument if + % we're called from @code, as @code{@value{foo-bar_}}, though. + % So \let them to their normal equivalents. + \let-\realdash \let_\normalunderscore + } +} + +% We have this subroutine so that we can handle at least some @value's +% properly in indexes (we call \makevalueexpandable in \indexdummies). +% The command has to be fully expandable (if the variable is set), since +% the result winds up in the index file. This means that if the +% variable's value contains other Texinfo commands, it's almost certain +% it will fail (although perhaps we could fix that with sufficient work +% to do a one-level expansion on the result, instead of complete). +% +\def\expandablevalue#1{% + \expandafter\ifx\csname SET#1\endcsname\relax + {[No value for ``#1'']}% + \message{Variable `#1', used in @value, is not set.}% + \else + \csname SET#1\endcsname + \fi +} + +% @ifset VAR ... @end ifset reads the `...' iff VAR has been defined +% with @set. +% +% To get special treatment of `@end ifset,' call \makeond and the redefine. +% +\makecond{ifset} +\def\ifset{\parsearg{\doifset{\let\next=\ifsetfail}}} +\def\doifset#1#2{% + {% + \makevalueexpandable + \let\next=\empty + \expandafter\ifx\csname SET#2\endcsname\relax + #1% If not set, redefine \next. + \fi + \expandafter + }\next +} +\def\ifsetfail{\doignore{ifset}} + +% @ifclear VAR ... @end ifclear reads the `...' iff VAR has never been +% defined with @set, or has been undefined with @clear. +% +% The `\else' inside the `\doifset' parameter is a trick to reuse the +% above code: if the variable is not set, do nothing, if it is set, +% then redefine \next to \ifclearfail. +% +\makecond{ifclear} +\def\ifclear{\parsearg{\doifset{\else \let\next=\ifclearfail}}} +\def\ifclearfail{\doignore{ifclear}} + +% @dircategory CATEGORY -- specify a category of the dir file +% which this file should belong to. Ignore this in TeX. +\let\dircategory=\comment + +% @defininfoenclose. +\let\definfoenclose=\comment + + +\message{indexing,} +% Index generation facilities + +% Define \newwrite to be identical to plain tex's \newwrite +% except not \outer, so it can be used within macros and \if's. +\edef\newwrite{\makecsname{ptexnewwrite}} + +% \newindex {foo} defines an index named foo. +% It automatically defines \fooindex such that +% \fooindex ...rest of line... puts an entry in the index foo. +% It also defines \fooindfile to be the number of the output channel for +% the file that accumulates this index. The file's extension is foo. +% The name of an index should be no more than 2 characters long +% for the sake of vms. +% +\def\newindex#1{% + \iflinks + \expandafter\newwrite \csname#1indfile\endcsname + \openout \csname#1indfile\endcsname \jobname.#1 % Open the file + \fi + \expandafter\xdef\csname#1index\endcsname{% % Define @#1index + \noexpand\doindex{#1}} +} + +% @defindex foo == \newindex{foo} +% +\def\defindex{\parsearg\newindex} + +% Define @defcodeindex, like @defindex except put all entries in @code. +% +\def\defcodeindex{\parsearg\newcodeindex} +% +\def\newcodeindex#1{% + \iflinks + \expandafter\newwrite \csname#1indfile\endcsname + \openout \csname#1indfile\endcsname \jobname.#1 + \fi + \expandafter\xdef\csname#1index\endcsname{% + \noexpand\docodeindex{#1}}% +} + + +% @synindex foo bar makes index foo feed into index bar. +% Do this instead of @defindex foo if you don't want it as a separate index. +% +% @syncodeindex foo bar similar, but put all entries made for index foo +% inside @code. +% +\def\synindex#1 #2 {\dosynindex\doindex{#1}{#2}} +\def\syncodeindex#1 #2 {\dosynindex\docodeindex{#1}{#2}} + +% #1 is \doindex or \docodeindex, #2 the index getting redefined (foo), +% #3 the target index (bar). +\def\dosynindex#1#2#3{% + % Only do \closeout if we haven't already done it, else we'll end up + % closing the target index. + \expandafter \ifx\csname donesynindex#2\endcsname \undefined + % The \closeout helps reduce unnecessary open files; the limit on the + % Acorn RISC OS is a mere 16 files. + \expandafter\closeout\csname#2indfile\endcsname + \expandafter\let\csname\donesynindex#2\endcsname = 1 + \fi + % redefine \fooindfile: + \expandafter\let\expandafter\temp\expandafter=\csname#3indfile\endcsname + \expandafter\let\csname#2indfile\endcsname=\temp + % redefine \fooindex: + \expandafter\xdef\csname#2index\endcsname{\noexpand#1{#3}}% +} + +% Define \doindex, the driver for all \fooindex macros. +% Argument #1 is generated by the calling \fooindex macro, +% and it is "foo", the name of the index. + +% \doindex just uses \parsearg; it calls \doind for the actual work. +% This is because \doind is more useful to call from other macros. + +% There is also \dosubind {index}{topic}{subtopic} +% which makes an entry in a two-level index such as the operation index. + +\def\doindex#1{\edef\indexname{#1}\parsearg\singleindexer} +\def\singleindexer #1{\doind{\indexname}{#1}} + +% like the previous two, but they put @code around the argument. +\def\docodeindex#1{\edef\indexname{#1}\parsearg\singlecodeindexer} +\def\singlecodeindexer #1{\doind{\indexname}{\code{#1}}} + +% Take care of Texinfo commands that can appear in an index entry. +% Since there are some commands we want to expand, and others we don't, +% we have to laboriously prevent expansion for those that we don't. +% +\def\indexdummies{% + \def\@{@}% change to @@ when we switch to @ as escape char in index files. + \def\ {\realbackslash\space }% + % Need these in case \tex is in effect and \{ is a \delimiter again. + % But can't use \lbracecmd and \rbracecmd because texindex assumes + % braces and backslashes are used only as delimiters. + \let\{ = \mylbrace + \let\} = \myrbrace + % + % \definedummyword defines \#1 as \realbackslash #1\space, thus + % effectively preventing its expansion. This is used only for control + % words, not control letters, because the \space would be incorrect + % for control characters, but is needed to separate the control word + % from whatever follows. + % + % For control letters, we have \definedummyletter, which omits the + % space. + % + % These can be used both for control words that take an argument and + % those that do not. If it is followed by {arg} in the input, then + % that will dutifully get written to the index (or wherever). + % + \def\definedummyword##1{% + \expandafter\def\csname ##1\endcsname{\realbackslash ##1\space}% + }% + \def\definedummyletter##1{% + \expandafter\def\csname ##1\endcsname{\realbackslash ##1}% + }% + \let\definedummyaccent\definedummyletter + % + % Do the redefinitions. + \commondummies +} + +% For the aux file, @ is the escape character. So we want to redefine +% everything using @ instead of \realbackslash. When everything uses +% @, this will be simpler. +% +\def\atdummies{% + \def\@{@@}% + \def\ {@ }% + \let\{ = \lbraceatcmd + \let\} = \rbraceatcmd + % + % (See comments in \indexdummies.) + \def\definedummyword##1{% + \expandafter\def\csname ##1\endcsname{@##1\space}% + }% + \def\definedummyletter##1{% + \expandafter\def\csname ##1\endcsname{@##1}% + }% + \let\definedummyaccent\definedummyletter + % + % Do the redefinitions. + \commondummies +} + +% Called from \indexdummies and \atdummies. \definedummyword and +% \definedummyletter must be defined first. +% +\def\commondummies{% + % + \normalturnoffactive + % + \commondummiesnofonts + % + \definedummyletter{_}% + % + % Non-English letters. + \definedummyword{AA}% + \definedummyword{AE}% + \definedummyword{L}% + \definedummyword{OE}% + \definedummyword{O}% + \definedummyword{aa}% + \definedummyword{ae}% + \definedummyword{l}% + \definedummyword{oe}% + \definedummyword{o}% + \definedummyword{ss}% + \definedummyword{exclamdown}% + \definedummyword{questiondown}% + \definedummyword{ordf}% + \definedummyword{ordm}% + % + % Although these internal commands shouldn't show up, sometimes they do. + \definedummyword{bf}% + \definedummyword{gtr}% + \definedummyword{hat}% + \definedummyword{less}% + \definedummyword{sf}% + \definedummyword{sl}% + \definedummyword{tclose}% + \definedummyword{tt}% + % + \definedummyword{LaTeX}% + \definedummyword{TeX}% + % + % Assorted special characters. + \definedummyword{bullet}% + \definedummyword{comma}% + \definedummyword{copyright}% + \definedummyword{registeredsymbol}% + \definedummyword{dots}% + \definedummyword{enddots}% + \definedummyword{equiv}% + \definedummyword{error}% + \definedummyword{euro}% + \definedummyword{expansion}% + \definedummyword{minus}% + \definedummyword{pounds}% + \definedummyword{point}% + \definedummyword{print}% + \definedummyword{result}% + % + % Handle some cases of @value -- where it does not contain any + % (non-fully-expandable) commands. + \makevalueexpandable + % + % Normal spaces, not active ones. + \unsepspaces + % + % No macro expansion. + \turnoffmacros +} + +% \commondummiesnofonts: common to \commondummies and \indexnofonts. +% +% Better have this without active chars. +{ + \catcode`\~=\other + \gdef\commondummiesnofonts{% + % Control letters and accents. + \definedummyletter{!}% + \definedummyaccent{"}% + \definedummyaccent{'}% + \definedummyletter{*}% + \definedummyaccent{,}% + \definedummyletter{.}% + \definedummyletter{/}% + \definedummyletter{:}% + \definedummyaccent{=}% + \definedummyletter{?}% + \definedummyaccent{^}% + \definedummyaccent{`}% + \definedummyaccent{~}% + \definedummyword{u}% + \definedummyword{v}% + \definedummyword{H}% + \definedummyword{dotaccent}% + \definedummyword{ringaccent}% + \definedummyword{tieaccent}% + \definedummyword{ubaraccent}% + \definedummyword{udotaccent}% + \definedummyword{dotless}% + % + % Texinfo font commands. + \definedummyword{b}% + \definedummyword{i}% + \definedummyword{r}% + \definedummyword{sc}% + \definedummyword{t}% + % + % Commands that take arguments. + \definedummyword{acronym}% + \definedummyword{cite}% + \definedummyword{code}% + \definedummyword{command}% + \definedummyword{dfn}% + \definedummyword{emph}% + \definedummyword{env}% + \definedummyword{file}% + \definedummyword{kbd}% + \definedummyword{key}% + \definedummyword{math}% + \definedummyword{option}% + \definedummyword{samp}% + \definedummyword{strong}% + \definedummyword{tie}% + \definedummyword{uref}% + \definedummyword{url}% + \definedummyword{var}% + \definedummyword{verb}% + \definedummyword{w}% + } +} + +% \indexnofonts is used when outputting the strings to sort the index +% by, and when constructing control sequence names. It eliminates all +% control sequences and just writes whatever the best ASCII sort string +% would be for a given command (usually its argument). +% +\def\indexnofonts{% + % Accent commands should become @asis. + \def\definedummyaccent##1{% + \expandafter\let\csname ##1\endcsname\asis + }% + % We can just ignore other control letters. + \def\definedummyletter##1{% + \expandafter\def\csname ##1\endcsname{}% + }% + % Hopefully, all control words can become @asis. + \let\definedummyword\definedummyaccent + % + \commondummiesnofonts + % + % Don't no-op \tt, since it isn't a user-level command + % and is used in the definitions of the active chars like <, >, |, etc. + % Likewise with the other plain tex font commands. + %\let\tt=\asis + % + \def\ { }% + \def\@{@}% + % how to handle braces? + \def\_{\normalunderscore}% + % + % Non-English letters. + \def\AA{AA}% + \def\AE{AE}% + \def\L{L}% + \def\OE{OE}% + \def\O{O}% + \def\aa{aa}% + \def\ae{ae}% + \def\l{l}% + \def\oe{oe}% + \def\o{o}% + \def\ss{ss}% + \def\exclamdown{!}% + \def\questiondown{?}% + \def\ordf{a}% + \def\ordm{o}% + % + \def\LaTeX{LaTeX}% + \def\TeX{TeX}% + % + % Assorted special characters. + % (The following {} will end up in the sort string, but that's ok.) + \def\bullet{bullet}% + \def\comma{,}% + \def\copyright{copyright}% + \def\registeredsymbol{R}% + \def\dots{...}% + \def\enddots{...}% + \def\equiv{==}% + \def\error{error}% + \def\euro{euro}% + \def\expansion{==>}% + \def\minus{-}% + \def\pounds{pounds}% + \def\point{.}% + \def\print{-|}% + \def\result{=>}% + % + % Don't write macro names. + \emptyusermacros +} + +\let\indexbackslash=0 %overridden during \printindex. +\let\SETmarginindex=\relax % put index entries in margin (undocumented)? + +% Most index entries go through here, but \dosubind is the general case. +% #1 is the index name, #2 is the entry text. +\def\doind#1#2{\dosubind{#1}{#2}{}} + +% Workhorse for all \fooindexes. +% #1 is name of index, #2 is stuff to put there, #3 is subentry -- +% empty if called from \doind, as we usually are (the main exception +% is with most defuns, which call us directly). +% +\def\dosubind#1#2#3{% + \iflinks + {% + % Store the main index entry text (including the third arg). + \toks0 = {#2}% + % If third arg is present, precede it with a space. + \def\thirdarg{#3}% + \ifx\thirdarg\empty \else + \toks0 = \expandafter{\the\toks0 \space #3}% + \fi + % + \edef\writeto{\csname#1indfile\endcsname}% + % + \ifvmode + \dosubindsanitize + \else + \dosubindwrite + \fi + }% + \fi +} + +% Write the entry in \toks0 to the index file: +% +\def\dosubindwrite{% + % Put the index entry in the margin if desired. + \ifx\SETmarginindex\relax\else + \insert\margin{\hbox{\vrule height8pt depth3pt width0pt \the\toks0}}% + \fi + % + % Remember, we are within a group. + \indexdummies % Must do this here, since \bf, etc expand at this stage + \escapechar=`\\ + \def\backslashcurfont{\indexbackslash}% \indexbackslash isn't defined now + % so it will be output as is; and it will print as backslash. + % + % Process the index entry with all font commands turned off, to + % get the string to sort by. + {\indexnofonts + \edef\temp{\the\toks0}% need full expansion + \xdef\indexsorttmp{\temp}% + }% + % + % Set up the complete index entry, with both the sort key and + % the original text, including any font commands. We write + % three arguments to \entry to the .?? file (four in the + % subentry case), texindex reduces to two when writing the .??s + % sorted result. + \edef\temp{% + \write\writeto{% + \string\entry{\indexsorttmp}{\noexpand\folio}{\the\toks0}}% + }% + \temp +} + +% Take care of unwanted page breaks: +% +% If a skip is the last thing on the list now, preserve it +% by backing up by \lastskip, doing the \write, then inserting +% the skip again. Otherwise, the whatsit generated by the +% \write will make \lastskip zero. The result is that sequences +% like this: +% @end defun +% @tindex whatever +% @defun ... +% will have extra space inserted, because the \medbreak in the +% start of the @defun won't see the skip inserted by the @end of +% the previous defun. +% +% But don't do any of this if we're not in vertical mode. We +% don't want to do a \vskip and prematurely end a paragraph. +% +% Avoid page breaks due to these extra skips, too. +% +% But wait, there is a catch there: +% We'll have to check whether \lastskip is zero skip. \ifdim is not +% sufficient for this purpose, as it ignores stretch and shrink parts +% of the skip. The only way seems to be to check the textual +% representation of the skip. +% +% The following is almost like \def\zeroskipmacro{0.0pt} except that +% the ``p'' and ``t'' characters have catcode \other, not 11 (letter). +% +\edef\zeroskipmacro{\expandafter\the\csname z@skip\endcsname} +% +% ..., ready, GO: +% +\def\dosubindsanitize{% + % \lastskip and \lastpenalty cannot both be nonzero simultaneously. + \skip0 = \lastskip + \edef\lastskipmacro{\the\lastskip}% + \count255 = \lastpenalty + % + % If \lastskip is nonzero, that means the last item was a + % skip. And since a skip is discardable, that means this + % -\skip0 glue we're inserting is preceded by a + % non-discardable item, therefore it is not a potential + % breakpoint, therefore no \nobreak needed. + \ifx\lastskipmacro\zeroskipmacro + \else + \vskip-\skip0 + \fi + % + \dosubindwrite + % + \ifx\lastskipmacro\zeroskipmacro + % If \lastskip was zero, perhaps the last item was a penalty, and + % perhaps it was >=10000, e.g., a \nobreak. In that case, we want + % to re-insert the same penalty (values >10000 are used for various + % signals); since we just inserted a non-discardable item, any + % following glue (such as a \parskip) would be a breakpoint. For example: + % + % @deffn deffn-whatever + % @vindex index-whatever + % Description. + % would allow a break between the index-whatever whatsit + % and the "Description." paragraph. + \ifnum\count255>9999 \penalty\count255 \fi + \else + % On the other hand, if we had a nonzero \lastskip, + % this make-up glue would be preceded by a non-discardable item + % (the whatsit from the \write), so we must insert a \nobreak. + \nobreak\vskip\skip0 + \fi +} + +% The index entry written in the file actually looks like +% \entry {sortstring}{page}{topic} +% or +% \entry {sortstring}{page}{topic}{subtopic} +% The texindex program reads in these files and writes files +% containing these kinds of lines: +% \initial {c} +% before the first topic whose initial is c +% \entry {topic}{pagelist} +% for a topic that is used without subtopics +% \primary {topic} +% for the beginning of a topic that is used with subtopics +% \secondary {subtopic}{pagelist} +% for each subtopic. + +% Define the user-accessible indexing commands +% @findex, @vindex, @kindex, @cindex. + +\def\findex {\fnindex} +\def\kindex {\kyindex} +\def\cindex {\cpindex} +\def\vindex {\vrindex} +\def\tindex {\tpindex} +\def\pindex {\pgindex} + +\def\cindexsub {\begingroup\obeylines\cindexsub} +{\obeylines % +\gdef\cindexsub "#1" #2^^M{\endgroup % +\dosubind{cp}{#2}{#1}}} + +% Define the macros used in formatting output of the sorted index material. + +% @printindex causes a particular index (the ??s file) to get printed. +% It does not print any chapter heading (usually an @unnumbered). +% +\parseargdef\printindex{\begingroup + \dobreak \chapheadingskip{10000}% + % + \smallfonts \rm + \tolerance = 9500 + \everypar = {}% don't want the \kern\-parindent from indentation suppression. + % + % See if the index file exists and is nonempty. + % Change catcode of @ here so that if the index file contains + % \initial {@} + % as its first line, TeX doesn't complain about mismatched braces + % (because it thinks @} is a control sequence). + \catcode`\@ = 11 + \openin 1 \jobname.#1s + \ifeof 1 + % \enddoublecolumns gets confused if there is no text in the index, + % and it loses the chapter title and the aux file entries for the + % index. The easiest way to prevent this problem is to make sure + % there is some text. + \putwordIndexNonexistent + \else + % + % If the index file exists but is empty, then \openin leaves \ifeof + % false. We have to make TeX try to read something from the file, so + % it can discover if there is anything in it. + \read 1 to \temp + \ifeof 1 + \putwordIndexIsEmpty + \else + % Index files are almost Texinfo source, but we use \ as the escape + % character. It would be better to use @, but that's too big a change + % to make right now. + \def\indexbackslash{\backslashcurfont}% + \catcode`\\ = 0 + \escapechar = `\\ + \begindoublecolumns + \input \jobname.#1s + \enddoublecolumns + \fi + \fi + \closein 1 +\endgroup} + +% These macros are used by the sorted index file itself. +% Change them to control the appearance of the index. + +\def\initial#1{{% + % Some minor font changes for the special characters. + \let\tentt=\sectt \let\tt=\sectt \let\sf=\sectt + % + % Remove any glue we may have, we'll be inserting our own. + \removelastskip + % + % We like breaks before the index initials, so insert a bonus. + \nobreak + \vskip 0pt plus 3\baselineskip + \penalty 0 + \vskip 0pt plus -3\baselineskip + % + % Typeset the initial. Making this add up to a whole number of + % baselineskips increases the chance of the dots lining up from column + % to column. It still won't often be perfect, because of the stretch + % we need before each entry, but it's better. + % + % No shrink because it confuses \balancecolumns. + \vskip 1.67\baselineskip plus .5\baselineskip + \leftline{\secbf #1}% + % Do our best not to break after the initial. + \nobreak + \vskip .33\baselineskip plus .1\baselineskip +}} + +% \entry typesets a paragraph consisting of the text (#1), dot leaders, and +% then page number (#2) flushed to the right margin. It is used for index +% and table of contents entries. The paragraph is indented by \leftskip. +% +% A straightforward implementation would start like this: +% \def\entry#1#2{... +% But this frozes the catcodes in the argument, and can cause problems to +% @code, which sets - active. This problem was fixed by a kludge--- +% ``-'' was active throughout whole index, but this isn't really right. +% +% The right solution is to prevent \entry from swallowing the whole text. +% --kasal, 21nov03 +\def\entry{% + \begingroup + % + % Start a new paragraph if necessary, so our assignments below can't + % affect previous text. + \par + % + % Do not fill out the last line with white space. + \parfillskip = 0in + % + % No extra space above this paragraph. + \parskip = 0in + % + % Do not prefer a separate line ending with a hyphen to fewer lines. + \finalhyphendemerits = 0 + % + % \hangindent is only relevant when the entry text and page number + % don't both fit on one line. In that case, bob suggests starting the + % dots pretty far over on the line. Unfortunately, a large + % indentation looks wrong when the entry text itself is broken across + % lines. So we use a small indentation and put up with long leaders. + % + % \hangafter is reset to 1 (which is the value we want) at the start + % of each paragraph, so we need not do anything with that. + \hangindent = 2em + % + % When the entry text needs to be broken, just fill out the first line + % with blank space. + \rightskip = 0pt plus1fil + % + % A bit of stretch before each entry for the benefit of balancing + % columns. + \vskip 0pt plus1pt + % + % Swallow the left brace of the text (first parameter): + \afterassignment\doentry + \let\temp = +} +\def\doentry{% + \bgroup % Instead of the swallowed brace. + \noindent + \aftergroup\finishentry + % And now comes the text of the entry. +} +\def\finishentry#1{% + % #1 is the page number. + % + % The following is kludged to not output a line of dots in the index if + % there are no page numbers. The next person who breaks this will be + % cursed by a Unix daemon. + \def\tempa{{\rm }}% + \def\tempb{#1}% + \edef\tempc{\tempa}% + \edef\tempd{\tempb}% + \ifx\tempc\tempd + \ % + \else + % + % If we must, put the page number on a line of its own, and fill out + % this line with blank space. (The \hfil is overwhelmed with the + % fill leaders glue in \indexdotfill if the page number does fit.) + \hfil\penalty50 + \null\nobreak\indexdotfill % Have leaders before the page number. + % + % The `\ ' here is removed by the implicit \unskip that TeX does as + % part of (the primitive) \par. Without it, a spurious underfull + % \hbox ensues. + \ifpdf + \pdfgettoks#1.% + \ \the\toksA + \else + \ #1% + \fi + \fi + \par + \endgroup +} + +% Like \dotfill except takes at least 1 em. +\def\indexdotfill{\cleaders + \hbox{$\mathsurround=0pt \mkern1.5mu ${\it .}$ \mkern1.5mu$}\hskip 1em plus 1fill} + +\def\primary #1{\line{#1\hfil}} + +\newskip\secondaryindent \secondaryindent=0.5cm +\def\secondary#1#2{{% + \parfillskip=0in + \parskip=0in + \hangindent=1in + \hangafter=1 + \noindent\hskip\secondaryindent\hbox{#1}\indexdotfill + \ifpdf + \pdfgettoks#2.\ \the\toksA % The page number ends the paragraph. + \else + #2 + \fi + \par +}} + +% Define two-column mode, which we use to typeset indexes. +% Adapted from the TeXbook, page 416, which is to say, +% the manmac.tex format used to print the TeXbook itself. +\catcode`\@=11 + +\newbox\partialpage +\newdimen\doublecolumnhsize + +\def\begindoublecolumns{\begingroup % ended by \enddoublecolumns + % Grab any single-column material above us. + \output = {% + % + % Here is a possibility not foreseen in manmac: if we accumulate a + % whole lot of material, we might end up calling this \output + % routine twice in a row (see the doublecol-lose test, which is + % essentially a couple of indexes with @setchapternewpage off). In + % that case we just ship out what is in \partialpage with the normal + % output routine. Generally, \partialpage will be empty when this + % runs and this will be a no-op. See the indexspread.tex test case. + \ifvoid\partialpage \else + \onepageout{\pagecontents\partialpage}% + \fi + % + \global\setbox\partialpage = \vbox{% + % Unvbox the main output page. + \unvbox\PAGE + \kern-\topskip \kern\baselineskip + }% + }% + \eject % run that output routine to set \partialpage + % + % Use the double-column output routine for subsequent pages. + \output = {\doublecolumnout}% + % + % Change the page size parameters. We could do this once outside this + % routine, in each of @smallbook, @afourpaper, and the default 8.5x11 + % format, but then we repeat the same computation. Repeating a couple + % of assignments once per index is clearly meaningless for the + % execution time, so we may as well do it in one place. + % + % First we halve the line length, less a little for the gutter between + % the columns. We compute the gutter based on the line length, so it + % changes automatically with the paper format. The magic constant + % below is chosen so that the gutter has the same value (well, +-<1pt) + % as it did when we hard-coded it. + % + % We put the result in a separate register, \doublecolumhsize, so we + % can restore it in \pagesofar, after \hsize itself has (potentially) + % been clobbered. + % + \doublecolumnhsize = \hsize + \advance\doublecolumnhsize by -.04154\hsize + \divide\doublecolumnhsize by 2 + \hsize = \doublecolumnhsize + % + % Double the \vsize as well. (We don't need a separate register here, + % since nobody clobbers \vsize.) + \vsize = 2\vsize +} + +% The double-column output routine for all double-column pages except +% the last. +% +\def\doublecolumnout{% + \splittopskip=\topskip \splitmaxdepth=\maxdepth + % Get the available space for the double columns -- the normal + % (undoubled) page height minus any material left over from the + % previous page. + \dimen@ = \vsize + \divide\dimen@ by 2 + \advance\dimen@ by -\ht\partialpage + % + % box0 will be the left-hand column, box2 the right. + \setbox0=\vsplit255 to\dimen@ \setbox2=\vsplit255 to\dimen@ + \onepageout\pagesofar + \unvbox255 + \penalty\outputpenalty +} +% +% Re-output the contents of the output page -- any previous material, +% followed by the two boxes we just split, in box0 and box2. +\def\pagesofar{% + \unvbox\partialpage + % + \hsize = \doublecolumnhsize + \wd0=\hsize \wd2=\hsize + \hbox to\pagewidth{\box0\hfil\box2}% +} +% +% All done with double columns. +\def\enddoublecolumns{% + \output = {% + % Split the last of the double-column material. Leave it on the + % current page, no automatic page break. + \balancecolumns + % + % If we end up splitting too much material for the current page, + % though, there will be another page break right after this \output + % invocation ends. Having called \balancecolumns once, we do not + % want to call it again. Therefore, reset \output to its normal + % definition right away. (We hope \balancecolumns will never be + % called on to balance too much material, but if it is, this makes + % the output somewhat more palatable.) + \global\output = {\onepageout{\pagecontents\PAGE}}% + }% + \eject + \endgroup % started in \begindoublecolumns + % + % \pagegoal was set to the doubled \vsize above, since we restarted + % the current page. We're now back to normal single-column + % typesetting, so reset \pagegoal to the normal \vsize (after the + % \endgroup where \vsize got restored). + \pagegoal = \vsize +} +% +% Called at the end of the double column material. +\def\balancecolumns{% + \setbox0 = \vbox{\unvbox255}% like \box255 but more efficient, see p.120. + \dimen@ = \ht0 + \advance\dimen@ by \topskip + \advance\dimen@ by-\baselineskip + \divide\dimen@ by 2 % target to split to + %debug\message{final 2-column material height=\the\ht0, target=\the\dimen@.}% + \splittopskip = \topskip + % Loop until we get a decent breakpoint. + {% + \vbadness = 10000 + \loop + \global\setbox3 = \copy0 + \global\setbox1 = \vsplit3 to \dimen@ + \ifdim\ht3>\dimen@ + \global\advance\dimen@ by 1pt + \repeat + }% + %debug\message{split to \the\dimen@, column heights: \the\ht1, \the\ht3.}% + \setbox0=\vbox to\dimen@{\unvbox1}% + \setbox2=\vbox to\dimen@{\unvbox3}% + % + \pagesofar +} +\catcode`\@ = \other + + +\message{sectioning,} +% Chapters, sections, etc. + +% \unnumberedno is an oxymoron, of course. But we count the unnumbered +% sections so that we can refer to them unambiguously in the pdf +% outlines by their "section number". We avoid collisions with chapter +% numbers by starting them at 10000. (If a document ever has 10000 +% chapters, we're in trouble anyway, I'm sure.) +\newcount\unnumberedno \unnumberedno = 10000 +\newcount\chapno +\newcount\secno \secno=0 +\newcount\subsecno \subsecno=0 +\newcount\subsubsecno \subsubsecno=0 + +% This counter is funny since it counts through charcodes of letters A, B, ... +\newcount\appendixno \appendixno = `\@ +% +% \def\appendixletter{\char\the\appendixno} +% We do the following ugly conditional instead of the above simple +% construct for the sake of pdftex, which needs the actual +% letter in the expansion, not just typeset. +% +\def\appendixletter{% + \ifnum\appendixno=`A A% + \else\ifnum\appendixno=`B B% + \else\ifnum\appendixno=`C C% + \else\ifnum\appendixno=`D D% + \else\ifnum\appendixno=`E E% + \else\ifnum\appendixno=`F F% + \else\ifnum\appendixno=`G G% + \else\ifnum\appendixno=`H H% + \else\ifnum\appendixno=`I I% + \else\ifnum\appendixno=`J J% + \else\ifnum\appendixno=`K K% + \else\ifnum\appendixno=`L L% + \else\ifnum\appendixno=`M M% + \else\ifnum\appendixno=`N N% + \else\ifnum\appendixno=`O O% + \else\ifnum\appendixno=`P P% + \else\ifnum\appendixno=`Q Q% + \else\ifnum\appendixno=`R R% + \else\ifnum\appendixno=`S S% + \else\ifnum\appendixno=`T T% + \else\ifnum\appendixno=`U U% + \else\ifnum\appendixno=`V V% + \else\ifnum\appendixno=`W W% + \else\ifnum\appendixno=`X X% + \else\ifnum\appendixno=`Y Y% + \else\ifnum\appendixno=`Z Z% + % The \the is necessary, despite appearances, because \appendixletter is + % expanded while writing the .toc file. \char\appendixno is not + % expandable, thus it is written literally, thus all appendixes come out + % with the same letter (or @) in the toc without it. + \else\char\the\appendixno + \fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi + \fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi\fi} + +% Each @chapter defines this as the name of the chapter. +% page headings and footings can use it. @section does likewise. +% However, they are not reliable, because we don't use marks. +\def\thischapter{} +\def\thissection{} + +\newcount\absseclevel % used to calculate proper heading level +\newcount\secbase\secbase=0 % @raisesections/@lowersections modify this count + +% @raisesections: treat @section as chapter, @subsection as section, etc. +\def\raisesections{\global\advance\secbase by -1} +\let\up=\raisesections % original BFox name + +% @lowersections: treat @chapter as section, @section as subsection, etc. +\def\lowersections{\global\advance\secbase by 1} +\let\down=\lowersections % original BFox name + +% we only have subsub. +\chardef\maxseclevel = 3 +% +% A numbered section within an unnumbered changes to unnumbered too. +% To achive this, remember the "biggest" unnum. sec. we are currently in: +\chardef\unmlevel = \maxseclevel +% +% Trace whether the current chapter is an appendix or not: +% \chapheadtype is "N" or "A", unnumbered chapters are ignored. +\def\chapheadtype{N} + +% Choose a heading macro +% #1 is heading type +% #2 is heading level +% #3 is text for heading +\def\genhead#1#2#3{% + % Compute the abs. sec. level: + \absseclevel=#2 + \advance\absseclevel by \secbase + % Make sure \absseclevel doesn't fall outside the range: + \ifnum \absseclevel < 0 + \absseclevel = 0 + \else + \ifnum \absseclevel > 3 + \absseclevel = 3 + \fi + \fi + % The heading type: + \def\headtype{#1}% + \if \headtype U% + \ifnum \absseclevel < \unmlevel + \chardef\unmlevel = \absseclevel + \fi + \else + % Check for appendix sections: + \ifnum \absseclevel = 0 + \edef\chapheadtype{\headtype}% + \else + \if \headtype A\if \chapheadtype N% + \errmessage{@appendix... within a non-appendix chapter}% + \fi\fi + \fi + % Check for numbered within unnumbered: + \ifnum \absseclevel > \unmlevel + \def\headtype{U}% + \else + \chardef\unmlevel = 3 + \fi + \fi + % Now print the heading: + \if \headtype U% + \ifcase\absseclevel + \unnumberedzzz{#3}% + \or \unnumberedseczzz{#3}% + \or \unnumberedsubseczzz{#3}% + \or \unnumberedsubsubseczzz{#3}% + \fi + \else + \if \headtype A% + \ifcase\absseclevel + \appendixzzz{#3}% + \or \appendixsectionzzz{#3}% + \or \appendixsubseczzz{#3}% + \or \appendixsubsubseczzz{#3}% + \fi + \else + \ifcase\absseclevel + \chapterzzz{#3}% + \or \seczzz{#3}% + \or \numberedsubseczzz{#3}% + \or \numberedsubsubseczzz{#3}% + \fi + \fi + \fi + \suppressfirstparagraphindent +} + +% an interface: +\def\numhead{\genhead N} +\def\apphead{\genhead A} +\def\unnmhead{\genhead U} + +% @chapter, @appendix, @unnumbered. Increment top-level counter, reset +% all lower-level sectioning counters to zero. +% +% Also set \chaplevelprefix, which we prepend to @float sequence numbers +% (e.g., figures), q.v. By default (before any chapter), that is empty. +\let\chaplevelprefix = \empty +% +\outer\parseargdef\chapter{\numhead0{#1}} % normally numhead0 calls chapterzzz +\def\chapterzzz#1{% + % section resetting is \global in case the chapter is in a group, such + % as an @include file. + \global\secno=0 \global\subsecno=0 \global\subsubsecno=0 + \global\advance\chapno by 1 + % + % Used for \float. + \gdef\chaplevelprefix{\the\chapno.}% + \resetallfloatnos + % + \message{\putwordChapter\space \the\chapno}% + % + % Write the actual heading. + \chapmacro{#1}{Ynumbered}{\the\chapno}% + % + % So @section and the like are numbered underneath this chapter. + \global\let\section = \numberedsec + \global\let\subsection = \numberedsubsec + \global\let\subsubsection = \numberedsubsubsec +} + +\outer\parseargdef\appendix{\apphead0{#1}} % normally apphead0 calls appendixzzz +\def\appendixzzz#1{% + \global\secno=0 \global\subsecno=0 \global\subsubsecno=0 + \global\advance\appendixno by 1 + \gdef\chaplevelprefix{\appendixletter.}% + \resetallfloatnos + % + \def\appendixnum{\putwordAppendix\space \appendixletter}% + \message{\appendixnum}% + % + \chapmacro{#1}{Yappendix}{\appendixletter}% + % + \global\let\section = \appendixsec + \global\let\subsection = \appendixsubsec + \global\let\subsubsection = \appendixsubsubsec +} + +\outer\parseargdef\unnumbered{\unnmhead0{#1}} % normally unnmhead0 calls unnumberedzzz +\def\unnumberedzzz#1{% + \global\secno=0 \global\subsecno=0 \global\subsubsecno=0 + \global\advance\unnumberedno by 1 + % + % Since an unnumbered has no number, no prefix for figures. + \global\let\chaplevelprefix = \empty + \resetallfloatnos + % + % This used to be simply \message{#1}, but TeX fully expands the + % argument to \message. Therefore, if #1 contained @-commands, TeX + % expanded them. For example, in `@unnumbered The @cite{Book}', TeX + % expanded @cite (which turns out to cause errors because \cite is meant + % to be executed, not expanded). + % + % Anyway, we don't want the fully-expanded definition of @cite to appear + % as a result of the \message, we just want `@cite' itself. We use + % \the to achieve this: TeX expands \the only once, + % simply yielding the contents of . (We also do this for + % the toc entries.) + \toks0 = {#1}% + \message{(\the\toks0)}% + % + \chapmacro{#1}{Ynothing}{\the\unnumberedno}% + % + \global\let\section = \unnumberedsec + \global\let\subsection = \unnumberedsubsec + \global\let\subsubsection = \unnumberedsubsubsec +} + +% @centerchap is like @unnumbered, but the heading is centered. +\outer\parseargdef\centerchap{% + % Well, we could do the following in a group, but that would break + % an assumption that \chapmacro is called at the outermost level. + % Thus we are safer this way: --kasal, 24feb04 + \let\centerparametersmaybe = \centerparameters + \unnmhead0{#1}% + \let\centerparametersmaybe = \relax +} + +% @top is like @unnumbered. +\let\top\unnumbered + +% Sections. +\outer\parseargdef\numberedsec{\numhead1{#1}} % normally calls seczzz +\def\seczzz#1{% + \global\subsecno=0 \global\subsubsecno=0 \global\advance\secno by 1 + \sectionheading{#1}{sec}{Ynumbered}{\the\chapno.\the\secno}% +} + +\outer\parseargdef\appendixsection{\apphead1{#1}} % normally calls appendixsectionzzz +\def\appendixsectionzzz#1{% + \global\subsecno=0 \global\subsubsecno=0 \global\advance\secno by 1 + \sectionheading{#1}{sec}{Yappendix}{\appendixletter.\the\secno}% +} +\let\appendixsec\appendixsection + +\outer\parseargdef\unnumberedsec{\unnmhead1{#1}} % normally calls unnumberedseczzz +\def\unnumberedseczzz#1{% + \global\subsecno=0 \global\subsubsecno=0 \global\advance\secno by 1 + \sectionheading{#1}{sec}{Ynothing}{\the\unnumberedno.\the\secno}% +} + +% Subsections. +\outer\parseargdef\numberedsubsec{\numhead2{#1}} % normally calls numberedsubseczzz +\def\numberedsubseczzz#1{% + \global\subsubsecno=0 \global\advance\subsecno by 1 + \sectionheading{#1}{subsec}{Ynumbered}{\the\chapno.\the\secno.\the\subsecno}% +} + +\outer\parseargdef\appendixsubsec{\apphead2{#1}} % normally calls appendixsubseczzz +\def\appendixsubseczzz#1{% + \global\subsubsecno=0 \global\advance\subsecno by 1 + \sectionheading{#1}{subsec}{Yappendix}% + {\appendixletter.\the\secno.\the\subsecno}% +} + +\outer\parseargdef\unnumberedsubsec{\unnmhead2{#1}} %normally calls unnumberedsubseczzz +\def\unnumberedsubseczzz#1{% + \global\subsubsecno=0 \global\advance\subsecno by 1 + \sectionheading{#1}{subsec}{Ynothing}% + {\the\unnumberedno.\the\secno.\the\subsecno}% +} + +% Subsubsections. +\outer\parseargdef\numberedsubsubsec{\numhead3{#1}} % normally numberedsubsubseczzz +\def\numberedsubsubseczzz#1{% + \global\advance\subsubsecno by 1 + \sectionheading{#1}{subsubsec}{Ynumbered}% + {\the\chapno.\the\secno.\the\subsecno.\the\subsubsecno}% +} + +\outer\parseargdef\appendixsubsubsec{\apphead3{#1}} % normally appendixsubsubseczzz +\def\appendixsubsubseczzz#1{% + \global\advance\subsubsecno by 1 + \sectionheading{#1}{subsubsec}{Yappendix}% + {\appendixletter.\the\secno.\the\subsecno.\the\subsubsecno}% +} + +\outer\parseargdef\unnumberedsubsubsec{\unnmhead3{#1}} %normally unnumberedsubsubseczzz +\def\unnumberedsubsubseczzz#1{% + \global\advance\subsubsecno by 1 + \sectionheading{#1}{subsubsec}{Ynothing}% + {\the\unnumberedno.\the\secno.\the\subsecno.\the\subsubsecno}% +} + +% These macros control what the section commands do, according +% to what kind of chapter we are in (ordinary, appendix, or unnumbered). +% Define them by default for a numbered chapter. +\let\section = \numberedsec +\let\subsection = \numberedsubsec +\let\subsubsection = \numberedsubsubsec + +% Define @majorheading, @heading and @subheading + +% NOTE on use of \vbox for chapter headings, section headings, and such: +% 1) We use \vbox rather than the earlier \line to permit +% overlong headings to fold. +% 2) \hyphenpenalty is set to 10000 because hyphenation in a +% heading is obnoxious; this forbids it. +% 3) Likewise, headings look best if no \parindent is used, and +% if justification is not attempted. Hence \raggedright. + + +\def\majorheading{% + {\advance\chapheadingskip by 10pt \chapbreak }% + \parsearg\chapheadingzzz +} + +\def\chapheading{\chapbreak \parsearg\chapheadingzzz} +\def\chapheadingzzz#1{% + {\chapfonts \vbox{\hyphenpenalty=10000\tolerance=5000 + \parindent=0pt\raggedright + \rm #1\hfill}}% + \bigskip \par\penalty 200\relax + \suppressfirstparagraphindent +} + +% @heading, @subheading, @subsubheading. +\parseargdef\heading{\sectionheading{#1}{sec}{Yomitfromtoc}{} + \suppressfirstparagraphindent} +\parseargdef\subheading{\sectionheading{#1}{subsec}{Yomitfromtoc}{} + \suppressfirstparagraphindent} +\parseargdef\subsubheading{\sectionheading{#1}{subsubsec}{Yomitfromtoc}{} + \suppressfirstparagraphindent} + +% These macros generate a chapter, section, etc. heading only +% (including whitespace, linebreaking, etc. around it), +% given all the information in convenient, parsed form. + +%%% Args are the skip and penalty (usually negative) +\def\dobreak#1#2{\par\ifdim\lastskip<#1\removelastskip\penalty#2\vskip#1\fi} + +%%% Define plain chapter starts, and page on/off switching for it +% Parameter controlling skip before chapter headings (if needed) + +\newskip\chapheadingskip + +\def\chapbreak{\dobreak \chapheadingskip {-4000}} +\def\chappager{\par\vfill\supereject} +\def\chapoddpage{\chappager \ifodd\pageno \else \hbox to 0pt{} \chappager\fi} + +\def\setchapternewpage #1 {\csname CHAPPAG#1\endcsname} + +\def\CHAPPAGoff{% +\global\let\contentsalignmacro = \chappager +\global\let\pchapsepmacro=\chapbreak +\global\let\pagealignmacro=\chappager} + +\def\CHAPPAGon{% +\global\let\contentsalignmacro = \chappager +\global\let\pchapsepmacro=\chappager +\global\let\pagealignmacro=\chappager +\global\def\HEADINGSon{\HEADINGSsingle}} + +\def\CHAPPAGodd{% +\global\let\contentsalignmacro = \chapoddpage +\global\let\pchapsepmacro=\chapoddpage +\global\let\pagealignmacro=\chapoddpage +\global\def\HEADINGSon{\HEADINGSdouble}} + +\CHAPPAGon + +% Chapter opening. +% +% #1 is the text, #2 is the section type (Ynumbered, Ynothing, +% Yappendix, Yomitfromtoc), #3 the chapter number. +% +% To test against our argument. +\def\Ynothingkeyword{Ynothing} +\def\Yomitfromtockeyword{Yomitfromtoc} +\def\Yappendixkeyword{Yappendix} +% +\def\chapmacro#1#2#3{% + \pchapsepmacro + {% + \chapfonts \rm + % + % Have to define \thissection before calling \donoderef, because the + % xref code eventually uses it. On the other hand, it has to be called + % after \pchapsepmacro, or the headline will change too soon. + \gdef\thissection{#1}% + \gdef\thischaptername{#1}% + % + % Only insert the separating space if we have a chapter/appendix + % number, and don't print the unnumbered ``number''. + \def\temptype{#2}% + \ifx\temptype\Ynothingkeyword + \setbox0 = \hbox{}% + \def\toctype{unnchap}% + \gdef\thischapter{#1}% + \else\ifx\temptype\Yomitfromtockeyword + \setbox0 = \hbox{}% contents like unnumbered, but no toc entry + \def\toctype{omit}% + \gdef\thischapter{}% + \else\ifx\temptype\Yappendixkeyword + \setbox0 = \hbox{\putwordAppendix{} #3\enspace}% + \def\toctype{app}% + % We don't substitute the actual chapter name into \thischapter + % because we don't want its macros evaluated now. And we don't + % use \thissection because that changes with each section. + % + \xdef\thischapter{\putwordAppendix{} \appendixletter: + \noexpand\thischaptername}% + \else + \setbox0 = \hbox{#3\enspace}% + \def\toctype{numchap}% + \xdef\thischapter{\putwordChapter{} \the\chapno: + \noexpand\thischaptername}% + \fi\fi\fi + % + % Write the toc entry for this chapter. Must come before the + % \donoderef, because we include the current node name in the toc + % entry, and \donoderef resets it to empty. + \writetocentry{\toctype}{#1}{#3}% + % + % For pdftex, we have to write out the node definition (aka, make + % the pdfdest) after any page break, but before the actual text has + % been typeset. If the destination for the pdf outline is after the + % text, then jumping from the outline may wind up with the text not + % being visible, for instance under high magnification. + \donoderef{#2}% + % + % Typeset the actual heading. + \vbox{\hyphenpenalty=10000 \tolerance=5000 \parindent=0pt \raggedright + \hangindent=\wd0 \centerparametersmaybe + \unhbox0 #1\par}% + }% + \nobreak\bigskip % no page break after a chapter title + \nobreak +} + +% @centerchap -- centered and unnumbered. +\let\centerparametersmaybe = \relax +\def\centerparameters{% + \advance\rightskip by 3\rightskip + \leftskip = \rightskip + \parfillskip = 0pt +} + + +% I don't think this chapter style is supported any more, so I'm not +% updating it with the new noderef stuff. We'll see. --karl, 11aug03. +% +\def\setchapterstyle #1 {\csname CHAPF#1\endcsname} +% +\def\unnchfopen #1{% +\chapoddpage {\chapfonts \vbox{\hyphenpenalty=10000\tolerance=5000 + \parindent=0pt\raggedright + \rm #1\hfill}}\bigskip \par\nobreak +} +\def\chfopen #1#2{\chapoddpage {\chapfonts +\vbox to 3in{\vfil \hbox to\hsize{\hfil #2} \hbox to\hsize{\hfil #1} \vfil}}% +\par\penalty 5000 % +} +\def\centerchfopen #1{% +\chapoddpage {\chapfonts \vbox{\hyphenpenalty=10000\tolerance=5000 + \parindent=0pt + \hfill {\rm #1}\hfill}}\bigskip \par\nobreak +} +\def\CHAPFopen{% + \global\let\chapmacro=\chfopen + \global\let\centerchapmacro=\centerchfopen} + + +% Section titles. These macros combine the section number parts and +% call the generic \sectionheading to do the printing. +% +\newskip\secheadingskip +\def\secheadingbreak{\dobreak \secheadingskip{-1000}} + +% Subsection titles. +\newskip\subsecheadingskip +\def\subsecheadingbreak{\dobreak \subsecheadingskip{-500}} + +% Subsubsection titles. +\def\subsubsecheadingskip{\subsecheadingskip} +\def\subsubsecheadingbreak{\subsecheadingbreak} + + +% Print any size, any type, section title. +% +% #1 is the text, #2 is the section level (sec/subsec/subsubsec), #3 is +% the section type for xrefs (Ynumbered, Ynothing, Yappendix), #4 is the +% section number. +% +\def\sectionheading#1#2#3#4{% + {% + % Switch to the right set of fonts. + \csname #2fonts\endcsname \rm + % + % Insert space above the heading. + \csname #2headingbreak\endcsname + % + % Only insert the space after the number if we have a section number. + \def\sectionlevel{#2}% + \def\temptype{#3}% + % + \ifx\temptype\Ynothingkeyword + \setbox0 = \hbox{}% + \def\toctype{unn}% + \gdef\thissection{#1}% + \else\ifx\temptype\Yomitfromtockeyword + % for @headings -- no section number, don't include in toc, + % and don't redefine \thissection. + \setbox0 = \hbox{}% + \def\toctype{omit}% + \let\sectionlevel=\empty + \else\ifx\temptype\Yappendixkeyword + \setbox0 = \hbox{#4\enspace}% + \def\toctype{app}% + \gdef\thissection{#1}% + \else + \setbox0 = \hbox{#4\enspace}% + \def\toctype{num}% + \gdef\thissection{#1}% + \fi\fi\fi + % + % Write the toc entry (before \donoderef). See comments in \chfplain. + \writetocentry{\toctype\sectionlevel}{#1}{#4}% + % + % Write the node reference (= pdf destination for pdftex). + % Again, see comments in \chfplain. + \donoderef{#3}% + % + % Output the actual section heading. + \vbox{\hyphenpenalty=10000 \tolerance=5000 \parindent=0pt \raggedright + \hangindent=\wd0 % zero if no section number + \unhbox0 #1}% + }% + % Add extra space after the heading -- half of whatever came above it. + % Don't allow stretch, though. + \kern .5 \csname #2headingskip\endcsname + % + % Do not let the kern be a potential breakpoint, as it would be if it + % was followed by glue. + \nobreak + % + % We'll almost certainly start a paragraph next, so don't let that + % glue accumulate. (Not a breakpoint because it's preceded by a + % discardable item.) + \vskip-\parskip + % + % This is purely so the last item on the list is a known \penalty > + % 10000. This is so \startdefun can avoid allowing breakpoints after + % section headings. Otherwise, it would insert a valid breakpoint between: + % + % @section sec-whatever + % @deffn def-whatever + \penalty 10001 +} + + +\message{toc,} +% Table of contents. +\newwrite\tocfile + +% Write an entry to the toc file, opening it if necessary. +% Called from @chapter, etc. +% +% Example usage: \writetocentry{sec}{Section Name}{\the\chapno.\the\secno} +% We append the current node name (if any) and page number as additional +% arguments for the \{chap,sec,...}entry macros which will eventually +% read this. The node name is used in the pdf outlines as the +% destination to jump to. +% +% We open the .toc file for writing here instead of at @setfilename (or +% any other fixed time) so that @contents can be anywhere in the document. +% But if #1 is `omit', then we don't do anything. This is used for the +% table of contents chapter openings themselves. +% +\newif\iftocfileopened +\def\omitkeyword{omit}% +% +\def\writetocentry#1#2#3{% + \edef\writetoctype{#1}% + \ifx\writetoctype\omitkeyword \else + \iftocfileopened\else + \immediate\openout\tocfile = \jobname.toc + \global\tocfileopenedtrue + \fi + % + \iflinks + \toks0 = {#2}% + \toks2 = \expandafter{\lastnode}% + \edef\temp{\write\tocfile{\realbackslash #1entry{\the\toks0}{#3}% + {\the\toks2}{\noexpand\folio}}}% + \temp + \fi + \fi + % + % Tell \shipout to create a pdf destination on each page, if we're + % writing pdf. These are used in the table of contents. We can't + % just write one on every page because the title pages are numbered + % 1 and 2 (the page numbers aren't printed), and so are the first + % two pages of the document. Thus, we'd have two destinations named + % `1', and two named `2'. + \ifpdf \global\pdfmakepagedesttrue \fi +} + +\newskip\contentsrightmargin \contentsrightmargin=1in +\newcount\savepageno +\newcount\lastnegativepageno \lastnegativepageno = -1 + +% Prepare to read what we've written to \tocfile. +% +\def\startcontents#1{% + % If @setchapternewpage on, and @headings double, the contents should + % start on an odd page, unlike chapters. Thus, we maintain + % \contentsalignmacro in parallel with \pagealignmacro. + % From: Torbjorn Granlund + \contentsalignmacro + \immediate\closeout\tocfile + % + % Don't need to put `Contents' or `Short Contents' in the headline. + % It is abundantly clear what they are. + \def\thischapter{}% + \chapmacro{#1}{Yomitfromtoc}{}% + % + \savepageno = \pageno + \begingroup % Set up to handle contents files properly. + \catcode`\\=0 \catcode`\{=1 \catcode`\}=2 \catcode`\@=11 + % We can't do this, because then an actual ^ in a section + % title fails, e.g., @chapter ^ -- exponentiation. --karl, 9jul97. + %\catcode`\^=7 % to see ^^e4 as \"a etc. juha@piuha.ydi.vtt.fi + \raggedbottom % Worry more about breakpoints than the bottom. + \advance\hsize by -\contentsrightmargin % Don't use the full line length. + % + % Roman numerals for page numbers. + \ifnum \pageno>0 \global\pageno = \lastnegativepageno \fi +} + + +% Normal (long) toc. +\def\contents{% + \startcontents{\putwordTOC}% + \openin 1 \jobname.toc + \ifeof 1 \else + \input \jobname.toc + \fi + \vfill \eject + \contentsalignmacro % in case @setchapternewpage odd is in effect + \ifeof 1 \else + \pdfmakeoutlines + \fi + \closein 1 + \endgroup + \lastnegativepageno = \pageno + \global\pageno = \savepageno +} + +% And just the chapters. +\def\summarycontents{% + \startcontents{\putwordShortTOC}% + % + \let\numchapentry = \shortchapentry + \let\appentry = \shortchapentry + \let\unnchapentry = \shortunnchapentry + % We want a true roman here for the page numbers. + \secfonts + \let\rm=\shortcontrm \let\bf=\shortcontbf + \let\sl=\shortcontsl \let\tt=\shortconttt + \rm + \hyphenpenalty = 10000 + \advance\baselineskip by 1pt % Open it up a little. + \def\numsecentry##1##2##3##4{} + \let\appsecentry = \numsecentry + \let\unnsecentry = \numsecentry + \let\numsubsecentry = \numsecentry + \let\appsubsecentry = \numsecentry + \let\unnsubsecentry = \numsecentry + \let\numsubsubsecentry = \numsecentry + \let\appsubsubsecentry = \numsecentry + \let\unnsubsubsecentry = \numsecentry + \openin 1 \jobname.toc + \ifeof 1 \else + \input \jobname.toc + \fi + \closein 1 + \vfill \eject + \contentsalignmacro % in case @setchapternewpage odd is in effect + \endgroup + \lastnegativepageno = \pageno + \global\pageno = \savepageno +} +\let\shortcontents = \summarycontents + +% Typeset the label for a chapter or appendix for the short contents. +% The arg is, e.g., `A' for an appendix, or `3' for a chapter. +% +\def\shortchaplabel#1{% + % This space should be enough, since a single number is .5em, and the + % widest letter (M) is 1em, at least in the Computer Modern fonts. + % But use \hss just in case. + % (This space doesn't include the extra space that gets added after + % the label; that gets put in by \shortchapentry above.) + % + % We'd like to right-justify chapter numbers, but that looks strange + % with appendix letters. And right-justifying numbers and + % left-justifying letters looks strange when there is less than 10 + % chapters. Have to read the whole toc once to know how many chapters + % there are before deciding ... + \hbox to 1em{#1\hss}% +} + +% These macros generate individual entries in the table of contents. +% The first argument is the chapter or section name. +% The last argument is the page number. +% The arguments in between are the chapter number, section number, ... + +% Chapters, in the main contents. +\def\numchapentry#1#2#3#4{\dochapentry{#2\labelspace#1}{#4}} +% +% Chapters, in the short toc. +% See comments in \dochapentry re vbox and related settings. +\def\shortchapentry#1#2#3#4{% + \tocentry{\shortchaplabel{#2}\labelspace #1}{\doshortpageno\bgroup#4\egroup}% +} + +% Appendices, in the main contents. +% Need the word Appendix, and a fixed-size box. +% +\def\appendixbox#1{% + % We use M since it's probably the widest letter. + \setbox0 = \hbox{\putwordAppendix{} M}% + \hbox to \wd0{\putwordAppendix{} #1\hss}} +% +\def\appentry#1#2#3#4{\dochapentry{\appendixbox{#2}\labelspace#1}{#4}} + +% Unnumbered chapters. +\def\unnchapentry#1#2#3#4{\dochapentry{#1}{#4}} +\def\shortunnchapentry#1#2#3#4{\tocentry{#1}{\doshortpageno\bgroup#4\egroup}} + +% Sections. +\def\numsecentry#1#2#3#4{\dosecentry{#2\labelspace#1}{#4}} +\let\appsecentry=\numsecentry +\def\unnsecentry#1#2#3#4{\dosecentry{#1}{#4}} + +% Subsections. +\def\numsubsecentry#1#2#3#4{\dosubsecentry{#2\labelspace#1}{#4}} +\let\appsubsecentry=\numsubsecentry +\def\unnsubsecentry#1#2#3#4{\dosubsecentry{#1}{#4}} + +% And subsubsections. +\def\numsubsubsecentry#1#2#3#4{\dosubsubsecentry{#2\labelspace#1}{#4}} +\let\appsubsubsecentry=\numsubsubsecentry +\def\unnsubsubsecentry#1#2#3#4{\dosubsubsecentry{#1}{#4}} + +% This parameter controls the indentation of the various levels. +% Same as \defaultparindent. +\newdimen\tocindent \tocindent = 15pt + +% Now for the actual typesetting. In all these, #1 is the text and #2 is the +% page number. +% +% If the toc has to be broken over pages, we want it to be at chapters +% if at all possible; hence the \penalty. +\def\dochapentry#1#2{% + \penalty-300 \vskip1\baselineskip plus.33\baselineskip minus.25\baselineskip + \begingroup + \chapentryfonts + \tocentry{#1}{\dopageno\bgroup#2\egroup}% + \endgroup + \nobreak\vskip .25\baselineskip plus.1\baselineskip +} + +\def\dosecentry#1#2{\begingroup + \secentryfonts \leftskip=\tocindent + \tocentry{#1}{\dopageno\bgroup#2\egroup}% +\endgroup} + +\def\dosubsecentry#1#2{\begingroup + \subsecentryfonts \leftskip=2\tocindent + \tocentry{#1}{\dopageno\bgroup#2\egroup}% +\endgroup} + +\def\dosubsubsecentry#1#2{\begingroup + \subsubsecentryfonts \leftskip=3\tocindent + \tocentry{#1}{\dopageno\bgroup#2\egroup}% +\endgroup} + +% We use the same \entry macro as for the index entries. +\let\tocentry = \entry + +% Space between chapter (or whatever) number and the title. +\def\labelspace{\hskip1em \relax} + +\def\dopageno#1{{\rm #1}} +\def\doshortpageno#1{{\rm #1}} + +\def\chapentryfonts{\secfonts \rm} +\def\secentryfonts{\textfonts} +\def\subsecentryfonts{\textfonts} +\def\subsubsecentryfonts{\textfonts} + + +\message{environments,} +% @foo ... @end foo. + +% @point{}, @result{}, @expansion{}, @print{}, @equiv{}. +% +% Since these characters are used in examples, it should be an even number of +% \tt widths. Each \tt character is 1en, so two makes it 1em. +% +\def\point{$\star$} +\def\result{\leavevmode\raise.15ex\hbox to 1em{\hfil$\Rightarrow$\hfil}} +\def\expansion{\leavevmode\raise.1ex\hbox to 1em{\hfil$\mapsto$\hfil}} +\def\print{\leavevmode\lower.1ex\hbox to 1em{\hfil$\dashv$\hfil}} +\def\equiv{\leavevmode\lower.1ex\hbox to 1em{\hfil$\ptexequiv$\hfil}} + +% The @error{} command. +% Adapted from the TeXbook's \boxit. +% +\newbox\errorbox +% +{\tentt \global\dimen0 = 3em}% Width of the box. +\dimen2 = .55pt % Thickness of rules +% The text. (`r' is open on the right, `e' somewhat less so on the left.) +\setbox0 = \hbox{\kern-.75pt \tensf error\kern-1.5pt} +% +\setbox\errorbox=\hbox to \dimen0{\hfil + \hsize = \dimen0 \advance\hsize by -5.8pt % Space to left+right. + \advance\hsize by -2\dimen2 % Rules. + \vbox{% + \hrule height\dimen2 + \hbox{\vrule width\dimen2 \kern3pt % Space to left of text. + \vtop{\kern2.4pt \box0 \kern2.4pt}% Space above/below. + \kern3pt\vrule width\dimen2}% Space to right. + \hrule height\dimen2} + \hfil} +% +\def\error{\leavevmode\lower.7ex\copy\errorbox} + +% @tex ... @end tex escapes into raw Tex temporarily. +% One exception: @ is still an escape character, so that @end tex works. +% But \@ or @@ will get a plain tex @ character. + +\envdef\tex{% + \catcode `\\=0 \catcode `\{=1 \catcode `\}=2 + \catcode `\$=3 \catcode `\&=4 \catcode `\#=6 + \catcode `\^=7 \catcode `\_=8 \catcode `\~=\active \let~=\tie + \catcode `\%=14 + \catcode `\+=\other + \catcode `\"=\other + \catcode `\|=\other + \catcode `\<=\other + \catcode `\>=\other + \escapechar=`\\ + % + \let\b=\ptexb + \let\bullet=\ptexbullet + \let\c=\ptexc + \let\,=\ptexcomma + \let\.=\ptexdot + \let\dots=\ptexdots + \let\equiv=\ptexequiv + \let\!=\ptexexclam + \let\i=\ptexi + \let\indent=\ptexindent + \let\noindent=\ptexnoindent + \let\{=\ptexlbrace + \let\+=\tabalign + \let\}=\ptexrbrace + \let\/=\ptexslash + \let\*=\ptexstar + \let\t=\ptext + % + \def\endldots{\mathinner{\ldots\ldots\ldots\ldots}}% + \def\enddots{\relax\ifmmode\endldots\else$\mathsurround=0pt \endldots\,$\fi}% + \def\@{@}% +} +% There is no need to define \Etex. + +% Define @lisp ... @end lisp. +% @lisp environment forms a group so it can rebind things, +% including the definition of @end lisp (which normally is erroneous). + +% Amount to narrow the margins by for @lisp. +\newskip\lispnarrowing \lispnarrowing=0.4in + +% This is the definition that ^^M gets inside @lisp, @example, and other +% such environments. \null is better than a space, since it doesn't +% have any width. +\def\lisppar{\null\endgraf} + +% This space is always present above and below environments. +\newskip\envskipamount \envskipamount = 0pt + +% Make spacing and below environment symmetrical. We use \parskip here +% to help in doing that, since in @example-like environments \parskip +% is reset to zero; thus the \afterenvbreak inserts no space -- but the +% start of the next paragraph will insert \parskip. +% +\def\aboveenvbreak{{% + % =10000 instead of <10000 because of a special case in \itemzzz and + % \sectionheading, q.v. + \ifnum \lastpenalty=10000 \else + \advance\envskipamount by \parskip + \endgraf + \ifdim\lastskip<\envskipamount + \removelastskip + % it's not a good place to break if the last penalty was \nobreak + % or better ... + \ifnum\lastpenalty<10000 \penalty-50 \fi + \vskip\envskipamount + \fi + \fi +}} + +\let\afterenvbreak = \aboveenvbreak + +% \nonarrowing is a flag. If "set", @lisp etc don't narrow margins. +\let\nonarrowing=\relax + +% @cartouche ... @end cartouche: draw rectangle w/rounded corners around +% environment contents. +\font\circle=lcircle10 +\newdimen\circthick +\newdimen\cartouter\newdimen\cartinner +\newskip\normbskip\newskip\normpskip\newskip\normlskip +\circthick=\fontdimen8\circle +% +\def\ctl{{\circle\char'013\hskip -6pt}}% 6pt from pl file: 1/2charwidth +\def\ctr{{\hskip 6pt\circle\char'010}} +\def\cbl{{\circle\char'012\hskip -6pt}} +\def\cbr{{\hskip 6pt\circle\char'011}} +\def\carttop{\hbox to \cartouter{\hskip\lskip + \ctl\leaders\hrule height\circthick\hfil\ctr + \hskip\rskip}} +\def\cartbot{\hbox to \cartouter{\hskip\lskip + \cbl\leaders\hrule height\circthick\hfil\cbr + \hskip\rskip}} +% +\newskip\lskip\newskip\rskip + +\envdef\cartouche{% + \ifhmode\par\fi % can't be in the midst of a paragraph. + \startsavinginserts + \lskip=\leftskip \rskip=\rightskip + \leftskip=0pt\rightskip=0pt % we want these *outside*. + \cartinner=\hsize \advance\cartinner by-\lskip + \advance\cartinner by-\rskip + \cartouter=\hsize + \advance\cartouter by 18.4pt % allow for 3pt kerns on either + % side, and for 6pt waste from + % each corner char, and rule thickness + \normbskip=\baselineskip \normpskip=\parskip \normlskip=\lineskip + % Flag to tell @lisp, etc., not to narrow margin. + \let\nonarrowing=\comment + \vbox\bgroup + \baselineskip=0pt\parskip=0pt\lineskip=0pt + \carttop + \hbox\bgroup + \hskip\lskip + \vrule\kern3pt + \vbox\bgroup + \kern3pt + \hsize=\cartinner + \baselineskip=\normbskip + \lineskip=\normlskip + \parskip=\normpskip + \vskip -\parskip + \comment % For explanation, see the end of \def\group. +} +\def\Ecartouche{% + \ifhmode\par\fi + \kern3pt + \egroup + \kern3pt\vrule + \hskip\rskip + \egroup + \cartbot + \egroup + \checkinserts +} + + +% This macro is called at the beginning of all the @example variants, +% inside a group. +\def\nonfillstart{% + \aboveenvbreak + \hfuzz = 12pt % Don't be fussy + \sepspaces % Make spaces be word-separators rather than space tokens. + \let\par = \lisppar % don't ignore blank lines + \obeylines % each line of input is a line of output + \parskip = 0pt + \parindent = 0pt + \emergencystretch = 0pt % don't try to avoid overfull boxes + % @cartouche defines \nonarrowing to inhibit narrowing + % at next level down. + \ifx\nonarrowing\relax + \advance \leftskip by \lispnarrowing + \exdentamount=\lispnarrowing + \fi + \let\exdent=\nofillexdent +} + +% If you want all examples etc. small: @set dispenvsize small. +% If you want even small examples the full size: @set dispenvsize nosmall. +% This affects the following displayed environments: +% @example, @display, @format, @lisp +% +\def\smallword{small} +\def\nosmallword{nosmall} +\let\SETdispenvsize\relax +\def\setnormaldispenv{% + \ifx\SETdispenvsize\smallword + \smallexamplefonts \rm + \fi +} +\def\setsmalldispenv{% + \ifx\SETdispenvsize\nosmallword + \else + \smallexamplefonts \rm + \fi +} + +% We often define two environments, @foo and @smallfoo. +% Let's do it by one command: +\def\makedispenv #1#2{ + \expandafter\envdef\csname#1\endcsname {\setnormaldispenv #2} + \expandafter\envdef\csname small#1\endcsname {\setsmalldispenv #2} + \expandafter\let\csname E#1\endcsname \afterenvbreak + \expandafter\let\csname Esmall#1\endcsname \afterenvbreak +} + +% Define two synonyms: +\def\maketwodispenvs #1#2#3{ + \makedispenv{#1}{#3} + \makedispenv{#2}{#3} +} + +% @lisp: indented, narrowed, typewriter font; @example: same as @lisp. +% +% @smallexample and @smalllisp: use smaller fonts. +% Originally contributed by Pavel@xerox. +% +\maketwodispenvs {lisp}{example}{% + \nonfillstart + \tt + \let\kbdfont = \kbdexamplefont % Allow @kbd to do something special. + \gobble % eat return +} + +% @display/@smalldisplay: same as @lisp except keep current font. +% +\makedispenv {display}{% + \nonfillstart + \gobble +} + +% @format/@smallformat: same as @display except don't narrow margins. +% +\makedispenv{format}{% + \let\nonarrowing = t% + \nonfillstart + \gobble +} + +% @flushleft: same as @format, but doesn't obey \SETdispenvsize. +\envdef\flushleft{% + \let\nonarrowing = t% + \nonfillstart + \gobble +} +\let\Eflushleft = \afterenvbreak + +% @flushright. +% +\envdef\flushright{% + \let\nonarrowing = t% + \nonfillstart + \advance\leftskip by 0pt plus 1fill + \gobble +} +\let\Eflushright = \afterenvbreak + + +% @quotation does normal linebreaking (hence we can't use \nonfillstart) +% and narrows the margins. We keep \parskip nonzero in general, since +% we're doing normal filling. So, when using \aboveenvbreak and +% \afterenvbreak, temporarily make \parskip 0. +% +\envdef\quotation{% + {\parskip=0pt \aboveenvbreak}% because \aboveenvbreak inserts \parskip + \parindent=0pt + % + % @cartouche defines \nonarrowing to inhibit narrowing at next level down. + \ifx\nonarrowing\relax + \advance\leftskip by \lispnarrowing + \advance\rightskip by \lispnarrowing + \exdentamount = \lispnarrowing + \let\nonarrowing = \relax + \fi + \parsearg\quotationlabel +} + +% We have retained a nonzero parskip for the environment, since we're +% doing normal filling. +% +\def\Equotation{% + \par + \ifx\quotationauthor\undefined\else + % indent a bit. + \leftline{\kern 2\leftskip \sl ---\quotationauthor}% + \fi + {\parskip=0pt \afterenvbreak}% +} + +% If we're given an argument, typeset it in bold with a colon after. +\def\quotationlabel#1{% + \def\temp{#1}% + \ifx\temp\empty \else + {\bf #1: }% + \fi +} + + +% LaTeX-like @verbatim...@end verbatim and @verb{...} +% If we want to allow any as delimiter, +% we need the curly braces so that makeinfo sees the @verb command, eg: +% `@verbx...x' would look like the '@verbx' command. --janneke@gnu.org +% +% [Knuth]: Donald Ervin Knuth, 1996. The TeXbook. +% +% [Knuth] p.344; only we need to do the other characters Texinfo sets +% active too. Otherwise, they get lost as the first character on a +% verbatim line. +\def\dospecials{% + \do\ \do\\\do\{\do\}\do\$\do\&% + \do\#\do\^\do\^^K\do\_\do\^^A\do\%\do\~% + \do\<\do\>\do\|\do\@\do+\do\"% +} +% +% [Knuth] p. 380 +\def\uncatcodespecials{% + \def\do##1{\catcode`##1=\other}\dospecials} +% +% [Knuth] pp. 380,381,391 +% Disable Spanish ligatures ?` and !` of \tt font +\begingroup + \catcode`\`=\active\gdef`{\relax\lq} +\endgroup +% +% Setup for the @verb command. +% +% Eight spaces for a tab +\begingroup + \catcode`\^^I=\active + \gdef\tabeightspaces{\catcode`\^^I=\active\def^^I{\ \ \ \ \ \ \ \ }} +\endgroup +% +\def\setupverb{% + \tt % easiest (and conventionally used) font for verbatim + \def\par{\leavevmode\endgraf}% + \catcode`\`=\active + \tabeightspaces + % Respect line breaks, + % print special symbols as themselves, and + % make each space count + % must do in this order: + \obeylines \uncatcodespecials \sepspaces +} + +% Setup for the @verbatim environment +% +% Real tab expansion +\newdimen\tabw \setbox0=\hbox{\tt\space} \tabw=8\wd0 % tab amount +% +\def\starttabbox{\setbox0=\hbox\bgroup} +\begingroup + \catcode`\^^I=\active + \gdef\tabexpand{% + \catcode`\^^I=\active + \def^^I{\leavevmode\egroup + \dimen0=\wd0 % the width so far, or since the previous tab + \divide\dimen0 by\tabw + \multiply\dimen0 by\tabw % compute previous multiple of \tabw + \advance\dimen0 by\tabw % advance to next multiple of \tabw + \wd0=\dimen0 \box0 \starttabbox + }% + } +\endgroup +\def\setupverbatim{% + \nonfillstart + \advance\leftskip by -\defbodyindent + % Easiest (and conventionally used) font for verbatim + \tt + \def\par{\leavevmode\egroup\box0\endgraf}% + \catcode`\`=\active + \tabexpand + % Respect line breaks, + % print special symbols as themselves, and + % make each space count + % must do in this order: + \obeylines \uncatcodespecials \sepspaces + \everypar{\starttabbox}% +} + +% Do the @verb magic: verbatim text is quoted by unique +% delimiter characters. Before first delimiter expect a +% right brace, after last delimiter expect closing brace: +% +% \def\doverb'{'#1'}'{#1} +% +% [Knuth] p. 382; only eat outer {} +\begingroup + \catcode`[=1\catcode`]=2\catcode`\{=\other\catcode`\}=\other + \gdef\doverb{#1[\def\next##1#1}[##1\endgroup]\next] +\endgroup +% +\def\verb{\begingroup\setupverb\doverb} +% +% +% Do the @verbatim magic: define the macro \doverbatim so that +% the (first) argument ends when '@end verbatim' is reached, ie: +% +% \def\doverbatim#1@end verbatim{#1} +% +% For Texinfo it's a lot easier than for LaTeX, +% because texinfo's \verbatim doesn't stop at '\end{verbatim}': +% we need not redefine '\', '{' and '}'. +% +% Inspired by LaTeX's verbatim command set [latex.ltx] +% +\begingroup + \catcode`\ =\active + \obeylines % + % ignore everything up to the first ^^M, that's the newline at the end + % of the @verbatim input line itself. Otherwise we get an extra blank + % line in the output. + \xdef\doverbatim#1^^M#2@end verbatim{#2\noexpand\end\gobble verbatim}% + % We really want {...\end verbatim} in the body of the macro, but + % without the active space; thus we have to use \xdef and \gobble. +\endgroup +% +\envdef\verbatim{% + \setupverbatim\doverbatim +} +\let\Everbatim = \afterenvbreak + + +% @verbatiminclude FILE - insert text of file in verbatim environment. +% +\def\verbatiminclude{\parseargusing\filenamecatcodes\doverbatiminclude} +% +\def\doverbatiminclude#1{% + {% + \makevalueexpandable + \setupverbatim + \input #1 + \afterenvbreak + }% +} + +% @copying ... @end copying. +% Save the text away for @insertcopying later. +% +% We save the uninterpreted tokens, rather than creating a box. +% Saving the text in a box would be much easier, but then all the +% typesetting commands (@smallbook, font changes, etc.) have to be done +% beforehand -- and a) we want @copying to be done first in the source +% file; b) letting users define the frontmatter in as flexible order as +% possible is very desirable. +% +\def\copying{\checkenv{}\begingroup\scanargctxt\docopying} +\def\docopying#1@end copying{\endgroup\def\copyingtext{#1}} +% +\def\insertcopying{% + \begingroup + \parindent = 0pt % paragraph indentation looks wrong on title page + \scanexp\copyingtext + \endgroup +} + +\message{defuns,} +% @defun etc. + +\newskip\defbodyindent \defbodyindent=.4in +\newskip\defargsindent \defargsindent=50pt +\newskip\deflastargmargin \deflastargmargin=18pt + +% Start the processing of @deffn: +\def\startdefun{% + \ifnum\lastpenalty<10000 + \medbreak + \else + % If there are two @def commands in a row, we'll have a \nobreak, + % which is there to keep the function description together with its + % header. But if there's nothing but headers, we need to allow a + % break somewhere. Check specifically for penalty 10002, inserted + % by \defargscommonending, instead of 10000, since the sectioning + % commands also insert a nobreak penalty, and we don't want to allow + % a break between a section heading and a defun. + % + \ifnum\lastpenalty=10002 \penalty2000 \fi + % + % Similarly, after a section heading, do not allow a break. + % But do insert the glue. + \medskip % preceded by discardable penalty, so not a breakpoint + \fi + % + \parindent=0in + \advance\leftskip by \defbodyindent + \exdentamount=\defbodyindent +} + +\def\dodefunx#1{% + % First, check whether we are in the right environment: + \checkenv#1% + % + % As above, allow line break if we have multiple x headers in a row. + % It's not a great place, though. + \ifnum\lastpenalty=10002 \penalty3000 \fi + % + % And now, it's time to reuse the body of the original defun: + \expandafter\gobbledefun#1% +} +\def\gobbledefun#1\startdefun{} + +% \printdefunline \deffnheader{text} +% +\def\printdefunline#1#2{% + \begingroup + % call \deffnheader: + #1#2 \endheader + % common ending: + \interlinepenalty = 10000 + \advance\rightskip by 0pt plus 1fil + \endgraf + \nobreak\vskip -\parskip + \penalty 10002 % signal to \startdefun and \dodefunx + % Some of the @defun-type tags do not enable magic parentheses, + % rendering the following check redundant. But we don't optimize. + \checkparencounts + \endgroup +} + +\def\Edefun{\endgraf\medbreak} + +% \makedefun{deffn} creates \deffn, \deffnx and \Edeffn; +% the only thing remainnig is to define \deffnheader. +% +\def\makedefun#1{% + \expandafter\let\csname E#1\endcsname = \Edefun + \edef\temp{\noexpand\domakedefun + \makecsname{#1}\makecsname{#1x}\makecsname{#1header}}% + \temp +} + +% \domakedefun \deffn \deffnx \deffnheader +% +% Define \deffn and \deffnx, without parameters. +% \deffnheader has to be defined explicitly. +% +\def\domakedefun#1#2#3{% + \envdef#1{% + \startdefun + \parseargusing\activeparens{\printdefunline#3}% + }% + \def#2{\dodefunx#1}% + \def#3% +} + +%%% Untyped functions: + +% @deffn category name args +\makedefun{deffn}{\deffngeneral{}} + +% @deffn category class name args +\makedefun{defop}#1 {\defopon{#1\ \putwordon}} + +% \defopon {category on}class name args +\def\defopon#1#2 {\deffngeneral{\putwordon\ \code{#2}}{#1\ \code{#2}} } + +% \deffngeneral {subind}category name args +% +\def\deffngeneral#1#2 #3 #4\endheader{% + % Remember that \dosubind{fn}{foo}{} is equivalent to \doind{fn}{foo}. + \dosubind{fn}{\code{#3}}{#1}% + \defname{#2}{}{#3}\magicamp\defunargs{#4\unskip}% +} + +%%% Typed functions: + +% @deftypefn category type name args +\makedefun{deftypefn}{\deftypefngeneral{}} + +% @deftypeop category class type name args +\makedefun{deftypeop}#1 {\deftypeopon{#1\ \putwordon}} + +% \deftypeopon {category on}class type name args +\def\deftypeopon#1#2 {\deftypefngeneral{\putwordon\ \code{#2}}{#1\ \code{#2}} } + +% \deftypefngeneral {subind}category type name args +% +\def\deftypefngeneral#1#2 #3 #4 #5\endheader{% + \dosubind{fn}{\code{#4}}{#1}% + \defname{#2}{#3}{#4}\defunargs{#5\unskip}% +} + +%%% Typed variables: + +% @deftypevr category type var args +\makedefun{deftypevr}{\deftypecvgeneral{}} + +% @deftypecv category class type var args +\makedefun{deftypecv}#1 {\deftypecvof{#1\ \putwordof}} + +% \deftypecvof {category of}class type var args +\def\deftypecvof#1#2 {\deftypecvgeneral{\putwordof\ \code{#2}}{#1\ \code{#2}} } + +% \deftypecvgeneral {subind}category type var args +% +\def\deftypecvgeneral#1#2 #3 #4 #5\endheader{% + \dosubind{vr}{\code{#4}}{#1}% + \defname{#2}{#3}{#4}\defunargs{#5\unskip}% +} + +%%% Untyped variables: + +% @defvr category var args +\makedefun{defvr}#1 {\deftypevrheader{#1} {} } + +% @defcv category class var args +\makedefun{defcv}#1 {\defcvof{#1\ \putwordof}} + +% \defcvof {category of}class var args +\def\defcvof#1#2 {\deftypecvof{#1}#2 {} } + +%%% Type: +% @deftp category name args +\makedefun{deftp}#1 #2 #3\endheader{% + \doind{tp}{\code{#2}}% + \defname{#1}{}{#2}\defunargs{#3\unskip}% +} + +% Remaining @defun-like shortcuts: +\makedefun{defun}{\deffnheader{\putwordDeffunc} } +\makedefun{defmac}{\deffnheader{\putwordDefmac} } +\makedefun{defspec}{\deffnheader{\putwordDefspec} } +\makedefun{deftypefun}{\deftypefnheader{\putwordDeffunc} } +\makedefun{defvar}{\defvrheader{\putwordDefvar} } +\makedefun{defopt}{\defvrheader{\putwordDefopt} } +\makedefun{deftypevar}{\deftypevrheader{\putwordDefvar} } +\makedefun{defmethod}{\defopon\putwordMethodon} +\makedefun{deftypemethod}{\deftypeopon\putwordMethodon} +\makedefun{defivar}{\defcvof\putwordInstanceVariableof} +\makedefun{deftypeivar}{\deftypecvof\putwordInstanceVariableof} + +% \defname, which formats the name of the @def (not the args). +% #1 is the category, such as "Function". +% #2 is the return type, if any. +% #3 is the function name. +% +% We are followed by (but not passed) the arguments, if any. +% +\def\defname#1#2#3{% + % Get the values of \leftskip and \rightskip as they were outside the @def... + \advance\leftskip by -\defbodyindent + % + % How we'll format the type name. Putting it in brackets helps + % distinguish it from the body text that may end up on the next line + % just below it. + \def\temp{#1}% + \setbox0=\hbox{\kern\deflastargmargin \ifx\temp\empty\else [\rm\temp]\fi} + % + % Figure out line sizes for the paragraph shape. + % The first line needs space for \box0; but if \rightskip is nonzero, + % we need only space for the part of \box0 which exceeds it: + \dimen0=\hsize \advance\dimen0 by -\wd0 \advance\dimen0 by \rightskip + % The continuations: + \dimen2=\hsize \advance\dimen2 by -\defargsindent + % (plain.tex says that \dimen1 should be used only as global.) + \parshape 2 0in \dimen0 \defargsindent \dimen2 + % + % Put the type name to the right margin. + \noindent + \hbox to 0pt{% + \hfil\box0 \kern-\hsize + % \hsize has to be shortened this way: + \kern\leftskip + % Intentionally do not respect \rightskip, since we need the space. + }% + % + % Allow all lines to be underfull without complaint: + \tolerance=10000 \hbadness=10000 + \exdentamount=\defbodyindent + {% + % defun fonts. We use typewriter by default (used to be bold) because: + % . we're printing identifiers, they should be in tt in principle. + % . in languages with many accents, such as Czech or French, it's + % common to leave accents off identifiers. The result looks ok in + % tt, but exceedingly strange in rm. + % . we don't want -- and --- to be treated as ligatures. + % . this still does not fix the ?` and !` ligatures, but so far no + % one has made identifiers using them :). + \df \tt + \def\temp{#2}% return value type + \ifx\temp\empty\else \tclose{\temp} \fi + #3% output function name + }% + {\rm\enskip}% hskip 0.5 em of \tenrm + % + \boldbrax + % arguments will be output next, if any. +} + +% Print arguments in slanted roman (not ttsl), inconsistently with using +% tt for the name. This is because literal text is sometimes needed in +% the argument list (groff manual), and ttsl and tt are not very +% distinguishable. Prevent hyphenation at `-' chars. +% +\def\defunargs#1{% + % use sl by default (not ttsl), + % tt for the names. + \df \sl \hyphenchar\font=0 + % + % On the other hand, if an argument has two dashes (for instance), we + % want a way to get ttsl. Let's try @var for that. + \let\var=\ttslanted + #1% + \sl\hyphenchar\font=45 +} + +% We want ()&[] to print specially on the defun line. +% +\def\activeparens{% + \catcode`\(=\active \catcode`\)=\active + \catcode`\[=\active \catcode`\]=\active + \catcode`\&=\active +} + +% Make control sequences which act like normal parenthesis chars. +\let\lparen = ( \let\rparen = ) + +% Be sure that we always have a definition for `(', etc. For example, +% if the fn name has parens in it, \boldbrax will not be in effect yet, +% so TeX would otherwise complain about undefined control sequence. +{ + \activeparens + \global\let(=\lparen \global\let)=\rparen + \global\let[=\lbrack \global\let]=\rbrack + \global\let& = \& + + \gdef\boldbrax{\let(=\opnr\let)=\clnr\let[=\lbrb\let]=\rbrb} + \gdef\magicamp{\let&=\amprm} +} + +\newcount\parencount + +% If we encounter &foo, then turn on ()-hacking afterwards +\newif\ifampseen +\def\amprm#1 {\ampseentrue{\bf\ }} + +\def\parenfont{% + \ifampseen + % At the first level, print parens in roman, + % otherwise use the default font. + \ifnum \parencount=1 \rm \fi + \else + % The \sf parens (in \boldbrax) actually are a little bolder than + % the contained text. This is especially needed for [ and ] . + \sf + \fi +} +\def\infirstlevel#1{% + \ifampseen + \ifnum\parencount=1 + #1% + \fi + \fi +} +\def\bfafterword#1 {#1 \bf} + +\def\opnr{% + \global\advance\parencount by 1 + {\parenfont(}% + \infirstlevel \bfafterword +} +\def\clnr{% + {\parenfont)}% + \infirstlevel \sl + \global\advance\parencount by -1 +} + +\newcount\brackcount +\def\lbrb{% + \global\advance\brackcount by 1 + {\bf[}% +} +\def\rbrb{% + {\bf]}% + \global\advance\brackcount by -1 +} + +\def\checkparencounts{% + \ifnum\parencount=0 \else \badparencount \fi + \ifnum\brackcount=0 \else \badbrackcount \fi +} +\def\badparencount{% + \errmessage{Unbalanced parentheses in @def}% + \global\parencount=0 +} +\def\badbrackcount{% + \errmessage{Unbalanced square braces in @def}% + \global\brackcount=0 +} + + +\message{macros,} +% @macro. + +% To do this right we need a feature of e-TeX, \scantokens, +% which we arrange to emulate with a temporary file in ordinary TeX. +\ifx\eTeXversion\undefined + \newwrite\macscribble + \def\scantokens#1{% + \toks0={#1}% + \immediate\openout\macscribble=\jobname.tmp + \immediate\write\macscribble{\the\toks0}% + \immediate\closeout\macscribble + \input \jobname.tmp + } +\fi + +\def\scanmacro#1{% + \begingroup + \newlinechar`\^^M + \let\xeatspaces\eatspaces + % Undo catcode changes of \startcontents and \doprintindex + % When called from @insertcopying or (short)caption, we need active + % backslash to get it printed correctly. Previously, we had + % \catcode`\\=\other instead. We'll see whether a problem appears + % with macro expansion. --kasal, 19aug04 + \catcode`\@=0 \catcode`\\=\active \escapechar=`\@ + % ... and \example + \spaceisspace + % + % Append \endinput to make sure that TeX does not see the ending newline. + % + % I've verified that it is necessary both for e-TeX and for ordinary TeX + % --kasal, 29nov03 + \scantokens{#1\endinput}% + \endgroup +} + +\def\scanexp#1{% + \edef\temp{\noexpand\scanmacro{#1}}% + \temp +} + +\newcount\paramno % Count of parameters +\newtoks\macname % Macro name +\newif\ifrecursive % Is it recursive? +\def\macrolist{} % List of all defined macros in the form + % \do\macro1\do\macro2... + +% Utility routines. +% This does \let #1 = #2, with \csnames; that is, +% \let \csname#1\endcsname = \csname#2\endcsname +% (except of course we have to play expansion games). +% +\def\cslet#1#2{% + \expandafter\let + \csname#1\expandafter\endcsname + \csname#2\endcsname +} + +% Trim leading and trailing spaces off a string. +% Concepts from aro-bend problem 15 (see CTAN). +{\catcode`\@=11 +\gdef\eatspaces #1{\expandafter\trim@\expandafter{#1 }} +\gdef\trim@ #1{\trim@@ @#1 @ #1 @ @@} +\gdef\trim@@ #1@ #2@ #3@@{\trim@@@\empty #2 @} +\def\unbrace#1{#1} +\unbrace{\gdef\trim@@@ #1 } #2@{#1} +} + +% Trim a single trailing ^^M off a string. +{\catcode`\^^M=\other \catcode`\Q=3% +\gdef\eatcr #1{\eatcra #1Q^^MQ}% +\gdef\eatcra#1^^MQ{\eatcrb#1Q}% +\gdef\eatcrb#1Q#2Q{#1}% +} + +% Macro bodies are absorbed as an argument in a context where +% all characters are catcode 10, 11 or 12, except \ which is active +% (as in normal texinfo). It is necessary to change the definition of \. + +% It's necessary to have hard CRs when the macro is executed. This is +% done by making ^^M (\endlinechar) catcode 12 when reading the macro +% body, and then making it the \newlinechar in \scanmacro. + +\def\scanctxt{% + \catcode`\"=\other + \catcode`\+=\other + \catcode`\<=\other + \catcode`\>=\other + \catcode`\@=\other + \catcode`\^=\other + \catcode`\_=\other + \catcode`\|=\other + \catcode`\~=\other +} + +\def\scanargctxt{% + \scanctxt + \catcode`\\=\other + \catcode`\^^M=\other +} + +\def\macrobodyctxt{% + \scanctxt + \catcode`\{=\other + \catcode`\}=\other + \catcode`\^^M=\other + \usembodybackslash +} + +\def\macroargctxt{% + \scanctxt + \catcode`\\=\other +} + +% \mbodybackslash is the definition of \ in @macro bodies. +% It maps \foo\ => \csname macarg.foo\endcsname => #N +% where N is the macro parameter number. +% We define \csname macarg.\endcsname to be \realbackslash, so +% \\ in macro replacement text gets you a backslash. + +{\catcode`@=0 @catcode`@\=@active + @gdef@usembodybackslash{@let\=@mbodybackslash} + @gdef@mbodybackslash#1\{@csname macarg.#1@endcsname} +} +\expandafter\def\csname macarg.\endcsname{\realbackslash} + +\def\macro{\recursivefalse\parsearg\macroxxx} +\def\rmacro{\recursivetrue\parsearg\macroxxx} + +\def\macroxxx#1{% + \getargs{#1}% now \macname is the macname and \argl the arglist + \ifx\argl\empty % no arguments + \paramno=0% + \else + \expandafter\parsemargdef \argl;% + \fi + \if1\csname ismacro.\the\macname\endcsname + \message{Warning: redefining \the\macname}% + \else + \expandafter\ifx\csname \the\macname\endcsname \relax + \else \errmessage{Macro name \the\macname\space already defined}\fi + \global\cslet{macsave.\the\macname}{\the\macname}% + \global\expandafter\let\csname ismacro.\the\macname\endcsname=1% + % Add the macroname to \macrolist + \toks0 = \expandafter{\macrolist\do}% + \xdef\macrolist{\the\toks0 + \expandafter\noexpand\csname\the\macname\endcsname}% + \fi + \begingroup \macrobodyctxt + \ifrecursive \expandafter\parsermacbody + \else \expandafter\parsemacbody + \fi} + +\parseargdef\unmacro{% + \if1\csname ismacro.#1\endcsname + \global\cslet{#1}{macsave.#1}% + \global\expandafter\let \csname ismacro.#1\endcsname=0% + % Remove the macro name from \macrolist: + \begingroup + \expandafter\let\csname#1\endcsname \relax + \let\do\unmacrodo + \xdef\macrolist{\macrolist}% + \endgroup + \else + \errmessage{Macro #1 not defined}% + \fi +} + +% Called by \do from \dounmacro on each macro. The idea is to omit any +% macro definitions that have been changed to \relax. +% +\def\unmacrodo#1{% + \ifx#1\relax + % remove this + \else + \noexpand\do \noexpand #1% + \fi +} + +% This makes use of the obscure feature that if the last token of a +% is #, then the preceding argument is delimited by +% an opening brace, and that opening brace is not consumed. +\def\getargs#1{\getargsxxx#1{}} +\def\getargsxxx#1#{\getmacname #1 \relax\getmacargs} +\def\getmacname #1 #2\relax{\macname={#1}} +\def\getmacargs#1{\def\argl{#1}} + +% Parse the optional {params} list. Set up \paramno and \paramlist +% so \defmacro knows what to do. Define \macarg.blah for each blah +% in the params list, to be ##N where N is the position in that list. +% That gets used by \mbodybackslash (above). + +% We need to get `macro parameter char #' into several definitions. +% The technique used is stolen from LaTeX: let \hash be something +% unexpandable, insert that wherever you need a #, and then redefine +% it to # just before using the token list produced. +% +% The same technique is used to protect \eatspaces till just before +% the macro is used. + +\def\parsemargdef#1;{\paramno=0\def\paramlist{}% + \let\hash\relax\let\xeatspaces\relax\parsemargdefxxx#1,;,} +\def\parsemargdefxxx#1,{% + \if#1;\let\next=\relax + \else \let\next=\parsemargdefxxx + \advance\paramno by 1% + \expandafter\edef\csname macarg.\eatspaces{#1}\endcsname + {\xeatspaces{\hash\the\paramno}}% + \edef\paramlist{\paramlist\hash\the\paramno,}% + \fi\next} + +% These two commands read recursive and nonrecursive macro bodies. +% (They're different since rec and nonrec macros end differently.) + +\long\def\parsemacbody#1@end macro% +{\xdef\temp{\eatcr{#1}}\endgroup\defmacro}% +\long\def\parsermacbody#1@end rmacro% +{\xdef\temp{\eatcr{#1}}\endgroup\defmacro}% + +% This defines the macro itself. There are six cases: recursive and +% nonrecursive macros of zero, one, and many arguments. +% Much magic with \expandafter here. +% \xdef is used so that macro definitions will survive the file +% they're defined in; @include reads the file inside a group. +\def\defmacro{% + \let\hash=##% convert placeholders to macro parameter chars + \ifrecursive + \ifcase\paramno + % 0 + \expandafter\xdef\csname\the\macname\endcsname{% + \noexpand\scanmacro{\temp}}% + \or % 1 + \expandafter\xdef\csname\the\macname\endcsname{% + \bgroup\noexpand\macroargctxt + \noexpand\braceorline + \expandafter\noexpand\csname\the\macname xxx\endcsname}% + \expandafter\xdef\csname\the\macname xxx\endcsname##1{% + \egroup\noexpand\scanmacro{\temp}}% + \else % many + \expandafter\xdef\csname\the\macname\endcsname{% + \bgroup\noexpand\macroargctxt + \noexpand\csname\the\macname xx\endcsname}% + \expandafter\xdef\csname\the\macname xx\endcsname##1{% + \expandafter\noexpand\csname\the\macname xxx\endcsname ##1,}% + \expandafter\expandafter + \expandafter\xdef + \expandafter\expandafter + \csname\the\macname xxx\endcsname + \paramlist{\egroup\noexpand\scanmacro{\temp}}% + \fi + \else + \ifcase\paramno + % 0 + \expandafter\xdef\csname\the\macname\endcsname{% + \noexpand\norecurse{\the\macname}% + \noexpand\scanmacro{\temp}\egroup}% + \or % 1 + \expandafter\xdef\csname\the\macname\endcsname{% + \bgroup\noexpand\macroargctxt + \noexpand\braceorline + \expandafter\noexpand\csname\the\macname xxx\endcsname}% + \expandafter\xdef\csname\the\macname xxx\endcsname##1{% + \egroup + \noexpand\norecurse{\the\macname}% + \noexpand\scanmacro{\temp}\egroup}% + \else % many + \expandafter\xdef\csname\the\macname\endcsname{% + \bgroup\noexpand\macroargctxt + \expandafter\noexpand\csname\the\macname xx\endcsname}% + \expandafter\xdef\csname\the\macname xx\endcsname##1{% + \expandafter\noexpand\csname\the\macname xxx\endcsname ##1,}% + \expandafter\expandafter + \expandafter\xdef + \expandafter\expandafter + \csname\the\macname xxx\endcsname + \paramlist{% + \egroup + \noexpand\norecurse{\the\macname}% + \noexpand\scanmacro{\temp}\egroup}% + \fi + \fi} + +\def\norecurse#1{\bgroup\cslet{#1}{macsave.#1}} + +% \braceorline decides whether the next nonwhitespace character is a +% {. If so it reads up to the closing }, if not, it reads the whole +% line. Whatever was read is then fed to the next control sequence +% as an argument (by \parsebrace or \parsearg) +\def\braceorline#1{\let\next=#1\futurelet\nchar\braceorlinexxx} +\def\braceorlinexxx{% + \ifx\nchar\bgroup\else + \expandafter\parsearg + \fi \next} + +% We want to disable all macros during \shipout so that they are not +% expanded by \write. +\def\turnoffmacros{\begingroup \def\do##1{\let\noexpand##1=\relax}% + \edef\next{\macrolist}\expandafter\endgroup\next} + +% For \indexnofonts, we need to get rid of all macros, leaving only the +% arguments (if present). Of course this is not nearly correct, but it +% is the best we can do for now. makeinfo does not expand macros in the +% argument to @deffn, which ends up writing an index entry, and texindex +% isn't prepared for an index sort entry that starts with \. +% +% Since macro invocations are followed by braces, we can just redefine them +% to take a single TeX argument. The case of a macro invocation that +% goes to end-of-line is not handled. +% +\def\emptyusermacros{\begingroup + \def\do##1{\let\noexpand##1=\noexpand\asis}% + \edef\next{\macrolist}\expandafter\endgroup\next} + + +% @alias. +% We need some trickery to remove the optional spaces around the equal +% sign. Just make them active and then expand them all to nothing. +\def\alias{\parseargusing\obeyspaces\aliasxxx} +\def\aliasxxx #1{\aliasyyy#1\relax} +\def\aliasyyy #1=#2\relax{% + {% + \expandafter\let\obeyedspace=\empty + \xdef\next{\global\let\makecsname{#1}=\makecsname{#2}}% + }% + \next +} + + +\message{cross references,} + +\newwrite\auxfile + +\newif\ifhavexrefs % True if xref values are known. +\newif\ifwarnedxrefs % True if we warned once that they aren't known. + +% @inforef is relatively simple. +\def\inforef #1{\inforefzzz #1,,,,**} +\def\inforefzzz #1,#2,#3,#4**{\putwordSee{} \putwordInfo{} \putwordfile{} \file{\ignorespaces #3{}}, + node \samp{\ignorespaces#1{}}} + +% @node's only job in TeX is to define \lastnode, which is used in +% cross-references. The @node line might or might not have commas, and +% might or might not have spaces before the first comma, like: +% @node foo , bar , ... +% We don't want such trailing spaces in the node name. +% +\parseargdef\node{\checkenv{}\donode #1 ,\finishnodeparse} +% +% also remove a trailing comma, in case of something like this: +% @node Help-Cross, , , Cross-refs +\def\donode#1 ,#2\finishnodeparse{\dodonode #1,\finishnodeparse} +\def\dodonode#1,#2\finishnodeparse{\gdef\lastnode{#1}} + +\let\nwnode=\node +\let\lastnode=\empty + +% Write a cross-reference definition for the current node. #1 is the +% type (Ynumbered, Yappendix, Ynothing). +% +\def\donoderef#1{% + \ifx\lastnode\empty\else + \setref{\lastnode}{#1}% + \global\let\lastnode=\empty + \fi +} + +% @anchor{NAME} -- define xref target at arbitrary point. +% +\newcount\savesfregister +% +\def\savesf{\relax \ifhmode \savesfregister=\spacefactor \fi} +\def\restoresf{\relax \ifhmode \spacefactor=\savesfregister \fi} +\def\anchor#1{\savesf \setref{#1}{Ynothing}\restoresf \ignorespaces} + +% \setref{NAME}{SNT} defines a cross-reference point NAME (a node or an +% anchor), which consists of three parts: +% 1) NAME-title - the current sectioning name taken from \thissection, +% or the anchor name. +% 2) NAME-snt - section number and type, passed as the SNT arg, or +% empty for anchors. +% 3) NAME-pg - the page number. +% +% This is called from \donoderef, \anchor, and \dofloat. In the case of +% floats, there is an additional part, which is not written here: +% 4) NAME-lof - the text as it should appear in a @listoffloats. +% +\def\setref#1#2{% + \pdfmkdest{#1}% + \iflinks + {% + \atdummies % preserve commands, but don't expand them + \turnoffactive + \otherbackslash + \edef\writexrdef##1##2{% + \write\auxfile{@xrdef{#1-% #1 of \setref, expanded by the \edef + ##1}{##2}}% these are parameters of \writexrdef + }% + \toks0 = \expandafter{\thissection}% + \immediate \writexrdef{title}{\the\toks0 }% + \immediate \writexrdef{snt}{\csname #2\endcsname}% \Ynumbered etc. + \writexrdef{pg}{\folio}% will be written later, during \shipout + }% + \fi +} + +% @xref, @pxref, and @ref generate cross-references. For \xrefX, #1 is +% the node name, #2 the name of the Info cross-reference, #3 the printed +% node name, #4 the name of the Info file, #5 the name of the printed +% manual. All but the node name can be omitted. +% +\def\pxref#1{\putwordsee{} \xrefX[#1,,,,,,,]} +\def\xref#1{\putwordSee{} \xrefX[#1,,,,,,,]} +\def\ref#1{\xrefX[#1,,,,,,,]} +\def\xrefX[#1,#2,#3,#4,#5,#6]{\begingroup + \unsepspaces + \def\printedmanual{\ignorespaces #5}% + \def\printedrefname{\ignorespaces #3}% + \setbox1=\hbox{\printedmanual\unskip}% + \setbox0=\hbox{\printedrefname\unskip}% + \ifdim \wd0 = 0pt + % No printed node name was explicitly given. + \expandafter\ifx\csname SETxref-automatic-section-title\endcsname\relax + % Use the node name inside the square brackets. + \def\printedrefname{\ignorespaces #1}% + \else + % Use the actual chapter/section title appear inside + % the square brackets. Use the real section title if we have it. + \ifdim \wd1 > 0pt + % It is in another manual, so we don't have it. + \def\printedrefname{\ignorespaces #1}% + \else + \ifhavexrefs + % We know the real title if we have the xref values. + \def\printedrefname{\refx{#1-title}{}}% + \else + % Otherwise just copy the Info node name. + \def\printedrefname{\ignorespaces #1}% + \fi% + \fi + \fi + \fi + % + % Make link in pdf output. + \ifpdf + \leavevmode + \getfilename{#4}% + {\turnoffactive \otherbackslash + \ifnum\filenamelength>0 + \startlink attr{/Border [0 0 0]}% + goto file{\the\filename.pdf} name{#1}% + \else + \startlink attr{/Border [0 0 0]}% + goto name{\pdfmkpgn{#1}}% + \fi + }% + \linkcolor + \fi + % + % Float references are printed completely differently: "Figure 1.2" + % instead of "[somenode], p.3". We distinguish them by the + % LABEL-title being set to a magic string. + {% + % Have to otherify everything special to allow the \csname to + % include an _ in the xref name, etc. + \indexnofonts + \turnoffactive + \otherbackslash + \expandafter\global\expandafter\let\expandafter\Xthisreftitle + \csname XR#1-title\endcsname + }% + \iffloat\Xthisreftitle + % If the user specified the print name (third arg) to the ref, + % print it instead of our usual "Figure 1.2". + \ifdim\wd0 = 0pt + \refx{#1-snt}% + \else + \printedrefname + \fi + % + % if the user also gave the printed manual name (fifth arg), append + % "in MANUALNAME". + \ifdim \wd1 > 0pt + \space \putwordin{} \cite{\printedmanual}% + \fi + \else + % node/anchor (non-float) references. + % + % If we use \unhbox0 and \unhbox1 to print the node names, TeX does not + % insert empty discretionaries after hyphens, which means that it will + % not find a line break at a hyphen in a node names. Since some manuals + % are best written with fairly long node names, containing hyphens, this + % is a loss. Therefore, we give the text of the node name again, so it + % is as if TeX is seeing it for the first time. + \ifdim \wd1 > 0pt + \putwordsection{} ``\printedrefname'' \putwordin{} \cite{\printedmanual}% + \else + % _ (for example) has to be the character _ for the purposes of the + % control sequence corresponding to the node, but it has to expand + % into the usual \leavevmode...\vrule stuff for purposes of + % printing. So we \turnoffactive for the \refx-snt, back on for the + % printing, back off for the \refx-pg. + {\turnoffactive \otherbackslash + % Only output a following space if the -snt ref is nonempty; for + % @unnumbered and @anchor, it won't be. + \setbox2 = \hbox{\ignorespaces \refx{#1-snt}{}}% + \ifdim \wd2 > 0pt \refx{#1-snt}\space\fi + }% + % output the `[mynode]' via a macro so it can be overridden. + \xrefprintnodename\printedrefname + % + % But we always want a comma and a space: + ,\space + % + % output the `page 3'. + \turnoffactive \otherbackslash \putwordpage\tie\refx{#1-pg}{}% + \fi + \fi + \endlink +\endgroup} + +% This macro is called from \xrefX for the `[nodename]' part of xref +% output. It's a separate macro only so it can be changed more easily, +% since square brackets don't work well in some documents. Particularly +% one that Bob is working on :). +% +\def\xrefprintnodename#1{[#1]} + +% Things referred to by \setref. +% +\def\Ynothing{} +\def\Yomitfromtoc{} +\def\Ynumbered{% + \ifnum\secno=0 + \putwordChapter@tie \the\chapno + \else \ifnum\subsecno=0 + \putwordSection@tie \the\chapno.\the\secno + \else \ifnum\subsubsecno=0 + \putwordSection@tie \the\chapno.\the\secno.\the\subsecno + \else + \putwordSection@tie \the\chapno.\the\secno.\the\subsecno.\the\subsubsecno + \fi\fi\fi +} +\def\Yappendix{% + \ifnum\secno=0 + \putwordAppendix@tie @char\the\appendixno{}% + \else \ifnum\subsecno=0 + \putwordSection@tie @char\the\appendixno.\the\secno + \else \ifnum\subsubsecno=0 + \putwordSection@tie @char\the\appendixno.\the\secno.\the\subsecno + \else + \putwordSection@tie + @char\the\appendixno.\the\secno.\the\subsecno.\the\subsubsecno + \fi\fi\fi +} + +% Define \refx{NAME}{SUFFIX} to reference a cross-reference string named NAME. +% If its value is nonempty, SUFFIX is output afterward. +% +\def\refx#1#2{% + {% + \indexnofonts + \otherbackslash + \expandafter\global\expandafter\let\expandafter\thisrefX + \csname XR#1\endcsname + }% + \ifx\thisrefX\relax + % If not defined, say something at least. + \angleleft un\-de\-fined\angleright + \iflinks + \ifhavexrefs + \message{\linenumber Undefined cross reference `#1'.}% + \else + \ifwarnedxrefs\else + \global\warnedxrefstrue + \message{Cross reference values unknown; you must run TeX again.}% + \fi + \fi + \fi + \else + % It's defined, so just use it. + \thisrefX + \fi + #2% Output the suffix in any case. +} + +% This is the macro invoked by entries in the aux file. Usually it's +% just a \def (we prepend XR to the control sequence name to avoid +% collisions). But if this is a float type, we have more work to do. +% +\def\xrdef#1#2{% + \expandafter\gdef\csname XR#1\endcsname{#2}% remember this xref value. + % + % Was that xref control sequence that we just defined for a float? + \expandafter\iffloat\csname XR#1\endcsname + % it was a float, and we have the (safe) float type in \iffloattype. + \expandafter\let\expandafter\floatlist + \csname floatlist\iffloattype\endcsname + % + % Is this the first time we've seen this float type? + \expandafter\ifx\floatlist\relax + \toks0 = {\do}% yes, so just \do + \else + % had it before, so preserve previous elements in list. + \toks0 = \expandafter{\floatlist\do}% + \fi + % + % Remember this xref in the control sequence \floatlistFLOATTYPE, + % for later use in \listoffloats. + \expandafter\xdef\csname floatlist\iffloattype\endcsname{\the\toks0{#1}}% + \fi +} + +% Read the last existing aux file, if any. No error if none exists. +% +\def\tryauxfile{% + \openin 1 \jobname.aux + \ifeof 1 \else + \readauxfile + \global\havexrefstrue + \fi + \closein 1 +} + +\def\readauxfile{\begingroup + \catcode`\^^@=\other + \catcode`\^^A=\other + \catcode`\^^B=\other + \catcode`\^^C=\other + \catcode`\^^D=\other + \catcode`\^^E=\other + \catcode`\^^F=\other + \catcode`\^^G=\other + \catcode`\^^H=\other + \catcode`\^^K=\other + \catcode`\^^L=\other + \catcode`\^^N=\other + \catcode`\^^P=\other + \catcode`\^^Q=\other + \catcode`\^^R=\other + \catcode`\^^S=\other + \catcode`\^^T=\other + \catcode`\^^U=\other + \catcode`\^^V=\other + \catcode`\^^W=\other + \catcode`\^^X=\other + \catcode`\^^Z=\other + \catcode`\^^[=\other + \catcode`\^^\=\other + \catcode`\^^]=\other + \catcode`\^^^=\other + \catcode`\^^_=\other + % It was suggested to set the catcode of ^ to 7, which would allow ^^e4 etc. + % in xref tags, i.e., node names. But since ^^e4 notation isn't + % supported in the main text, it doesn't seem desirable. Furthermore, + % that is not enough: for node names that actually contain a ^ + % character, we would end up writing a line like this: 'xrdef {'hat + % b-title}{'hat b} and \xrdef does a \csname...\endcsname on the first + % argument, and \hat is not an expandable control sequence. It could + % all be worked out, but why? Either we support ^^ or we don't. + % + % The other change necessary for this was to define \auxhat: + % \def\auxhat{\def^{'hat }}% extra space so ok if followed by letter + % and then to call \auxhat in \setq. + % + \catcode`\^=\other + % + % Special characters. Should be turned off anyway, but... + \catcode`\~=\other + \catcode`\[=\other + \catcode`\]=\other + \catcode`\"=\other + \catcode`\_=\other + \catcode`\|=\other + \catcode`\<=\other + \catcode`\>=\other + \catcode`\$=\other + \catcode`\#=\other + \catcode`\&=\other + \catcode`\%=\other + \catcode`+=\other % avoid \+ for paranoia even though we've turned it off + % + % This is to support \ in node names and titles, since the \ + % characters end up in a \csname. It's easier than + % leaving it active and making its active definition an actual \ + % character. What I don't understand is why it works in the *value* + % of the xrdef. Seems like it should be a catcode12 \, and that + % should not typeset properly. But it works, so I'm moving on for + % now. --karl, 15jan04. + \catcode`\\=\other + % + % Make the characters 128-255 be printing characters. + {% + \count 1=128 + \def\loop{% + \catcode\count 1=\other + \advance\count 1 by 1 + \ifnum \count 1<256 \loop \fi + }% + }% + % + % @ is our escape character in .aux files, and we need braces. + \catcode`\{=1 + \catcode`\}=2 + \catcode`\@=0 + % + \input \jobname.aux +\endgroup} + + +\message{insertions,} +% including footnotes. + +\newcount \footnoteno + +% The trailing space in the following definition for supereject is +% vital for proper filling; pages come out unaligned when you do a +% pagealignmacro call if that space before the closing brace is +% removed. (Generally, numeric constants should always be followed by a +% space to prevent strange expansion errors.) +\def\supereject{\par\penalty -20000\footnoteno =0 } + +% @footnotestyle is meaningful for info output only. +\let\footnotestyle=\comment + +{\catcode `\@=11 +% +% Auto-number footnotes. Otherwise like plain. +\gdef\footnote{% + \let\indent=\ptexindent + \let\noindent=\ptexnoindent + \global\advance\footnoteno by \@ne + \edef\thisfootno{$^{\the\footnoteno}$}% + % + % In case the footnote comes at the end of a sentence, preserve the + % extra spacing after we do the footnote number. + \let\@sf\empty + \ifhmode\edef\@sf{\spacefactor\the\spacefactor}\ptexslash\fi + % + % Remove inadvertent blank space before typesetting the footnote number. + \unskip + \thisfootno\@sf + \dofootnote +}% + +% Don't bother with the trickery in plain.tex to not require the +% footnote text as a parameter. Our footnotes don't need to be so general. +% +% Oh yes, they do; otherwise, @ifset (and anything else that uses +% \parseargline) fails inside footnotes because the tokens are fixed when +% the footnote is read. --karl, 16nov96. +% +\gdef\dofootnote{% + \insert\footins\bgroup + % We want to typeset this text as a normal paragraph, even if the + % footnote reference occurs in (for example) a display environment. + % So reset some parameters. + \hsize=\pagewidth + \interlinepenalty\interfootnotelinepenalty + \splittopskip\ht\strutbox % top baseline for broken footnotes + \splitmaxdepth\dp\strutbox + \floatingpenalty\@MM + \leftskip\z@skip + \rightskip\z@skip + \spaceskip\z@skip + \xspaceskip\z@skip + \parindent\defaultparindent + % + \smallfonts \rm + % + % Because we use hanging indentation in footnotes, a @noindent appears + % to exdent this text, so make it be a no-op. makeinfo does not use + % hanging indentation so @noindent can still be needed within footnote + % text after an @example or the like (not that this is good style). + \let\noindent = \relax + % + % Hang the footnote text off the number. Use \everypar in case the + % footnote extends for more than one paragraph. + \everypar = {\hang}% + \textindent{\thisfootno}% + % + % Don't crash into the line above the footnote text. Since this + % expands into a box, it must come within the paragraph, lest it + % provide a place where TeX can split the footnote. + \footstrut + \futurelet\next\fo@t +} +}%end \catcode `\@=11 + +% In case a @footnote appears in a vbox, save the footnote text and create +% the real \insert just after the vbox finished. Otherwise, the insertion +% would be lost. +% Similarily, if a @footnote appears inside an alignment, save the footnote +% text to a box and make the \insert when a row of the table is finished. +% And the same can be done for other insert classes. --kasal, 16nov03. + +% Replace the \insert primitive by a cheating macro. +% Deeper inside, just make sure that the saved insertions are not spilled +% out prematurely. +% +\def\startsavinginserts{% + \ifx \insert\ptexinsert + \let\insert\saveinsert + \else + \let\checkinserts\relax + \fi +} + +% This \insert replacement works for both \insert\footins{foo} and +% \insert\footins\bgroup foo\egroup, but it doesn't work for \insert27{foo}. +% +\def\saveinsert#1{% + \edef\next{\noexpand\savetobox \makeSAVEname#1}% + \afterassignment\next + % swallow the left brace + \let\temp = +} +\def\makeSAVEname#1{\makecsname{SAVE\expandafter\gobble\string#1}} +\def\savetobox#1{\global\setbox#1 = \vbox\bgroup \unvbox#1} + +\def\checksaveins#1{\ifvoid#1\else \placesaveins#1\fi} + +\def\placesaveins#1{% + \ptexinsert \csname\expandafter\gobblesave\string#1\endcsname + {\box#1}% +} + +% eat @SAVE -- beware, all of them have catcode \other: +{ + \def\dospecials{\do S\do A\do V\do E} \uncatcodespecials % ;-) + \gdef\gobblesave @SAVE{} +} + +% initialization: +\def\newsaveins #1{% + \edef\next{\noexpand\newsaveinsX \makeSAVEname#1}% + \next +} +\def\newsaveinsX #1{% + \csname newbox\endcsname #1% + \expandafter\def\expandafter\checkinserts\expandafter{\checkinserts + \checksaveins #1}% +} + +% initialize: +\let\checkinserts\empty +\newsaveins\footins +\newsaveins\margin + + +% @image. We use the macros from epsf.tex to support this. +% If epsf.tex is not installed and @image is used, we complain. +% +% Check for and read epsf.tex up front. If we read it only at @image +% time, we might be inside a group, and then its definitions would get +% undone and the next image would fail. +\openin 1 = epsf.tex +\ifeof 1 \else + % Do not bother showing banner with epsf.tex v2.7k (available in + % doc/epsf.tex and on ctan). + \def\epsfannounce{\toks0 = }% + \input epsf.tex +\fi +\closein 1 +% +% We will only complain once about lack of epsf.tex. +\newif\ifwarnednoepsf +\newhelp\noepsfhelp{epsf.tex must be installed for images to + work. It is also included in the Texinfo distribution, or you can get + it from ftp://tug.org/tex/epsf.tex.} +% +\def\image#1{% + \ifx\epsfbox\undefined + \ifwarnednoepsf \else + \errhelp = \noepsfhelp + \errmessage{epsf.tex not found, images will be ignored}% + \global\warnednoepsftrue + \fi + \else + \imagexxx #1,,,,,\finish + \fi +} +% +% Arguments to @image: +% #1 is (mandatory) image filename; we tack on .eps extension. +% #2 is (optional) width, #3 is (optional) height. +% #4 is (ignored optional) html alt text. +% #5 is (ignored optional) extension. +% #6 is just the usual extra ignored arg for parsing this stuff. +\newif\ifimagevmode +\def\imagexxx#1,#2,#3,#4,#5,#6\finish{\begingroup + \catcode`\^^M = 5 % in case we're inside an example + \normalturnoffactive % allow _ et al. in names + % If the image is by itself, center it. + \ifvmode + \imagevmodetrue + \nobreak\bigskip + % Usually we'll have text after the image which will insert + % \parskip glue, so insert it here too to equalize the space + % above and below. + \nobreak\vskip\parskip + \nobreak + \line\bgroup\hss + \fi + % + % Output the image. + \ifpdf + \dopdfimage{#1}{#2}{#3}% + \else + % \epsfbox itself resets \epsf?size at each figure. + \setbox0 = \hbox{\ignorespaces #2}\ifdim\wd0 > 0pt \epsfxsize=#2\relax \fi + \setbox0 = \hbox{\ignorespaces #3}\ifdim\wd0 > 0pt \epsfysize=#3\relax \fi + \epsfbox{#1.eps}% + \fi + % + \ifimagevmode \hss \egroup \bigbreak \fi % space after the image +\endgroup} + + +% @float FLOATTYPE,LABEL,LOC ... @end float for displayed figures, tables, +% etc. We don't actually implement floating yet, we always include the +% float "here". But it seemed the best name for the future. +% +\envparseargdef\float{\eatcommaspace\eatcommaspace\dofloat#1, , ,\finish} + +% There may be a space before second and/or third parameter; delete it. +\def\eatcommaspace#1, {#1,} + +% #1 is the optional FLOATTYPE, the text label for this float, typically +% "Figure", "Table", "Example", etc. Can't contain commas. If omitted, +% this float will not be numbered and cannot be referred to. +% +% #2 is the optional xref label. Also must be present for the float to +% be referable. +% +% #3 is the optional positioning argument; for now, it is ignored. It +% will somehow specify the positions allowed to float to (here, top, bottom). +% +% We keep a separate counter for each FLOATTYPE, which we reset at each +% chapter-level command. +\let\resetallfloatnos=\empty +% +\def\dofloat#1,#2,#3,#4\finish{% + \let\thiscaption=\empty + \let\thisshortcaption=\empty + % + % don't lose footnotes inside @float. + % + % BEWARE: when the floats start float, we have to issue warning whenever an + % insert appears inside a float which could possibly float. --kasal, 26may04 + % + \startsavinginserts + % + % We can't be used inside a paragraph. + \par + % + \vtop\bgroup + \def\floattype{#1}% + \def\floatlabel{#2}% + \def\floatloc{#3}% we do nothing with this yet. + % + \ifx\floattype\empty + \let\safefloattype=\empty + \else + {% + % the floattype might have accents or other special characters, + % but we need to use it in a control sequence name. + \indexnofonts + \turnoffactive + \xdef\safefloattype{\floattype}% + }% + \fi + % + % If label is given but no type, we handle that as the empty type. + \ifx\floatlabel\empty \else + % We want each FLOATTYPE to be numbered separately (Figure 1, + % Table 1, Figure 2, ...). (And if no label, no number.) + % + \expandafter\getfloatno\csname\safefloattype floatno\endcsname + \global\advance\floatno by 1 + % + {% + % This magic value for \thissection is output by \setref as the + % XREFLABEL-title value. \xrefX uses it to distinguish float + % labels (which have a completely different output format) from + % node and anchor labels. And \xrdef uses it to construct the + % lists of floats. + % + \edef\thissection{\floatmagic=\safefloattype}% + \setref{\floatlabel}{Yfloat}% + }% + \fi + % + % start with \parskip glue, I guess. + \vskip\parskip + % + % Don't suppress indentation if a float happens to start a section. + \restorefirstparagraphindent +} + +% we have these possibilities: +% @float Foo,lbl & @caption{Cap}: Foo 1.1: Cap +% @float Foo,lbl & no caption: Foo 1.1 +% @float Foo & @caption{Cap}: Foo: Cap +% @float Foo & no caption: Foo +% @float ,lbl & Caption{Cap}: 1.1: Cap +% @float ,lbl & no caption: 1.1 +% @float & @caption{Cap}: Cap +% @float & no caption: +% +\def\Efloat{% + \let\floatident = \empty + % + % In all cases, if we have a float type, it comes first. + \ifx\floattype\empty \else \def\floatident{\floattype}\fi + % + % If we have an xref label, the number comes next. + \ifx\floatlabel\empty \else + \ifx\floattype\empty \else % if also had float type, need tie first. + \appendtomacro\floatident{\tie}% + \fi + % the number. + \appendtomacro\floatident{\chaplevelprefix\the\floatno}% + \fi + % + % Start the printed caption with what we've constructed in + % \floatident, but keep it separate; we need \floatident again. + \let\captionline = \floatident + % + \ifx\thiscaption\empty \else + \ifx\floatident\empty \else + \appendtomacro\captionline{: }% had ident, so need a colon between + \fi + % + % caption text. + \appendtomacro\captionline{\scanexp\thiscaption}% + \fi + % + % If we have anything to print, print it, with space before. + % Eventually this needs to become an \insert. + \ifx\captionline\empty \else + \vskip.5\parskip + \captionline + % + % Space below caption. + \vskip\parskip + \fi + % + % If have an xref label, write the list of floats info. Do this + % after the caption, to avoid chance of it being a breakpoint. + \ifx\floatlabel\empty \else + % Write the text that goes in the lof to the aux file as + % \floatlabel-lof. Besides \floatident, we include the short + % caption if specified, else the full caption if specified, else nothing. + {% + \atdummies \turnoffactive \otherbackslash + % since we read the caption text in the macro world, where ^^M + % is turned into a normal character, we have to scan it back, so + % we don't write the literal three characters "^^M" into the aux file. + \scanexp{% + \xdef\noexpand\gtemp{% + \ifx\thisshortcaption\empty + \thiscaption + \else + \thisshortcaption + \fi + }% + }% + \immediate\write\auxfile{@xrdef{\floatlabel-lof}{\floatident + \ifx\gtemp\empty \else : \gtemp \fi}}% + }% + \fi + \egroup % end of \vtop + % + % place the captured inserts + % + % BEWARE: when the floats start float, we have to issue warning whenever an + % insert appears inside a float which could possibly float. --kasal, 26may04 + % + \checkinserts +} + +% Append the tokens #2 to the definition of macro #1, not expanding either. +% +\def\appendtomacro#1#2{% + \expandafter\def\expandafter#1\expandafter{#1#2}% +} + +% @caption, @shortcaption +% +\def\caption{\docaption\thiscaption} +\def\shortcaption{\docaption\thisshortcaption} +\def\docaption{\checkenv\float \bgroup\scanargctxt\defcaption} +\def\defcaption#1#2{\egroup \def#1{#2}} + +% The parameter is the control sequence identifying the counter we are +% going to use. Create it if it doesn't exist and assign it to \floatno. +\def\getfloatno#1{% + \ifx#1\relax + % Haven't seen this figure type before. + \csname newcount\endcsname #1% + % + % Remember to reset this floatno at the next chap. + \expandafter\gdef\expandafter\resetallfloatnos + \expandafter{\resetallfloatnos #1=0 }% + \fi + \let\floatno#1% +} + +% \setref calls this to get the XREFLABEL-snt value. We want an @xref +% to the FLOATLABEL to expand to "Figure 3.1". We call \setref when we +% first read the @float command. +% +\def\Yfloat{\floattype@tie \chaplevelprefix\the\floatno}% + +% Magic string used for the XREFLABEL-title value, so \xrefX can +% distinguish floats from other xref types. +\def\floatmagic{!!float!!} + +% #1 is the control sequence we are passed; we expand into a conditional +% which is true if #1 represents a float ref. That is, the magic +% \thissection value which we \setref above. +% +\def\iffloat#1{\expandafter\doiffloat#1==\finish} +% +% #1 is (maybe) the \floatmagic string. If so, #2 will be the +% (safe) float type for this float. We set \iffloattype to #2. +% +\def\doiffloat#1=#2=#3\finish{% + \def\temp{#1}% + \def\iffloattype{#2}% + \ifx\temp\floatmagic +} + +% @listoffloats FLOATTYPE - print a list of floats like a table of contents. +% +\parseargdef\listoffloats{% + \def\floattype{#1}% floattype + {% + % the floattype might have accents or other special characters, + % but we need to use it in a control sequence name. + \indexnofonts + \turnoffactive + \xdef\safefloattype{\floattype}% + }% + % + % \xrdef saves the floats as a \do-list in \floatlistSAFEFLOATTYPE. + \expandafter\ifx\csname floatlist\safefloattype\endcsname \relax + \ifhavexrefs + % if the user said @listoffloats foo but never @float foo. + \message{\linenumber No `\safefloattype' floats to list.}% + \fi + \else + \begingroup + \leftskip=\tocindent % indent these entries like a toc + \let\do=\listoffloatsdo + \csname floatlist\safefloattype\endcsname + \endgroup + \fi +} + +% This is called on each entry in a list of floats. We're passed the +% xref label, in the form LABEL-title, which is how we save it in the +% aux file. We strip off the -title and look up \XRLABEL-lof, which +% has the text we're supposed to typeset here. +% +% Figures without xref labels will not be included in the list (since +% they won't appear in the aux file). +% +\def\listoffloatsdo#1{\listoffloatsdoentry#1\finish} +\def\listoffloatsdoentry#1-title\finish{{% + % Can't fully expand XR#1-lof because it can contain anything. Just + % pass the control sequence. On the other hand, XR#1-pg is just the + % page number, and we want to fully expand that so we can get a link + % in pdf output. + \toksA = \expandafter{\csname XR#1-lof\endcsname}% + % + % use the same \entry macro we use to generate the TOC and index. + \edef\writeentry{\noexpand\entry{\the\toksA}{\csname XR#1-pg\endcsname}}% + \writeentry +}} + +\message{localization,} +% and i18n. + +% @documentlanguage is usually given very early, just after +% @setfilename. If done too late, it may not override everything +% properly. Single argument is the language abbreviation. +% It would be nice if we could set up a hyphenation file here. +% +\parseargdef\documentlanguage{% + \tex % read txi-??.tex file in plain TeX. + % Read the file if it exists. + \openin 1 txi-#1.tex + \ifeof 1 + \errhelp = \nolanghelp + \errmessage{Cannot read language file txi-#1.tex}% + \else + \input txi-#1.tex + \fi + \closein 1 + \endgroup +} +\newhelp\nolanghelp{The given language definition file cannot be found or +is empty. Maybe you need to install it? In the current directory +should work if nowhere else does.} + + +% @documentencoding should change something in TeX eventually, most +% likely, but for now just recognize it. +\let\documentencoding = \comment + + +% Page size parameters. +% +\newdimen\defaultparindent \defaultparindent = 15pt + +\chapheadingskip = 15pt plus 4pt minus 2pt +\secheadingskip = 12pt plus 3pt minus 2pt +\subsecheadingskip = 9pt plus 2pt minus 2pt + +% Prevent underfull vbox error messages. +\vbadness = 10000 + +% Don't be so finicky about underfull hboxes, either. +\hbadness = 2000 + +% Following George Bush, just get rid of widows and orphans. +\widowpenalty=10000 +\clubpenalty=10000 + +% Use TeX 3.0's \emergencystretch to help line breaking, but if we're +% using an old version of TeX, don't do anything. We want the amount of +% stretch added to depend on the line length, hence the dependence on +% \hsize. We call this whenever the paper size is set. +% +\def\setemergencystretch{% + \ifx\emergencystretch\thisisundefined + % Allow us to assign to \emergencystretch anyway. + \def\emergencystretch{\dimen0}% + \else + \emergencystretch = .15\hsize + \fi +} + +% Parameters in order: 1) textheight; 2) textwidth; 3) voffset; +% 4) hoffset; 5) binding offset; 6) topskip; 7) physical page height; 8) +% physical page width. +% +% We also call \setleading{\textleading}, so the caller should define +% \textleading. The caller should also set \parskip. +% +\def\internalpagesizes#1#2#3#4#5#6#7#8{% + \voffset = #3\relax + \topskip = #6\relax + \splittopskip = \topskip + % + \vsize = #1\relax + \advance\vsize by \topskip + \outervsize = \vsize + \advance\outervsize by 2\topandbottommargin + \pageheight = \vsize + % + \hsize = #2\relax + \outerhsize = \hsize + \advance\outerhsize by 0.5in + \pagewidth = \hsize + % + \normaloffset = #4\relax + \bindingoffset = #5\relax + % + \ifpdf + \pdfpageheight #7\relax + \pdfpagewidth #8\relax + \fi + % + \setleading{\textleading} + % + \parindent = \defaultparindent + \setemergencystretch +} + +% @letterpaper (the default). +\def\letterpaper{{\globaldefs = 1 + \parskip = 3pt plus 2pt minus 1pt + \textleading = 13.2pt + % + % If page is nothing but text, make it come out even. + \internalpagesizes{46\baselineskip}{6in}% + {\voffset}{.25in}% + {\bindingoffset}{36pt}% + {11in}{8.5in}% +}} + +% Use @smallbook to reset parameters for 7x9.5 (or so) format. +\def\smallbook{{\globaldefs = 1 + \parskip = 2pt plus 1pt + \textleading = 12pt + % + \internalpagesizes{7.5in}{5in}% + {\voffset}{.25in}% + {\bindingoffset}{16pt}% + {9.25in}{7in}% + % + \lispnarrowing = 0.3in + \tolerance = 700 + \hfuzz = 1pt + \contentsrightmargin = 0pt + \defbodyindent = .5cm +}} + +% Use @afourpaper to print on European A4 paper. +\def\afourpaper{{\globaldefs = 1 + \parskip = 3pt plus 2pt minus 1pt + \textleading = 13.2pt + % + % Double-side printing via postscript on Laserjet 4050 + % prints double-sided nicely when \bindingoffset=10mm and \hoffset=-6mm. + % To change the settings for a different printer or situation, adjust + % \normaloffset until the front-side and back-side texts align. Then + % do the same for \bindingoffset. You can set these for testing in + % your texinfo source file like this: + % @tex + % \global\normaloffset = -6mm + % \global\bindingoffset = 10mm + % @end tex + \internalpagesizes{51\baselineskip}{160mm} + {\voffset}{\hoffset}% + {\bindingoffset}{44pt}% + {297mm}{210mm}% + % + \tolerance = 700 + \hfuzz = 1pt + \contentsrightmargin = 0pt + \defbodyindent = 5mm +}} + +% Use @afivepaper to print on European A5 paper. +% From romildo@urano.iceb.ufop.br, 2 July 2000. +% He also recommends making @example and @lisp be small. +\def\afivepaper{{\globaldefs = 1 + \parskip = 2pt plus 1pt minus 0.1pt + \textleading = 12.5pt + % + \internalpagesizes{160mm}{120mm}% + {\voffset}{\hoffset}% + {\bindingoffset}{8pt}% + {210mm}{148mm}% + % + \lispnarrowing = 0.2in + \tolerance = 800 + \hfuzz = 1.2pt + \contentsrightmargin = 0pt + \defbodyindent = 2mm + \tableindent = 12mm +}} + +% A specific text layout, 24x15cm overall, intended for A4 paper. +\def\afourlatex{{\globaldefs = 1 + \afourpaper + \internalpagesizes{237mm}{150mm}% + {\voffset}{4.6mm}% + {\bindingoffset}{7mm}% + {297mm}{210mm}% + % + % Must explicitly reset to 0 because we call \afourpaper. + \globaldefs = 0 +}} + +% Use @afourwide to print on A4 paper in landscape format. +\def\afourwide{{\globaldefs = 1 + \afourpaper + \internalpagesizes{241mm}{165mm}% + {\voffset}{-2.95mm}% + {\bindingoffset}{7mm}% + {297mm}{210mm}% + \globaldefs = 0 +}} + +% @pagesizes TEXTHEIGHT[,TEXTWIDTH] +% Perhaps we should allow setting the margins, \topskip, \parskip, +% and/or leading, also. Or perhaps we should compute them somehow. +% +\parseargdef\pagesizes{\pagesizesyyy #1,,\finish} +\def\pagesizesyyy#1,#2,#3\finish{{% + \setbox0 = \hbox{\ignorespaces #2}\ifdim\wd0 > 0pt \hsize=#2\relax \fi + \globaldefs = 1 + % + \parskip = 3pt plus 2pt minus 1pt + \setleading{\textleading}% + % + \dimen0 = #1 + \advance\dimen0 by \voffset + % + \dimen2 = \hsize + \advance\dimen2 by \normaloffset + % + \internalpagesizes{#1}{\hsize}% + {\voffset}{\normaloffset}% + {\bindingoffset}{44pt}% + {\dimen0}{\dimen2}% +}} + +% Set default to letter. +% +\letterpaper + + +\message{and turning on texinfo input format.} + +% Define macros to output various characters with catcode for normal text. +\catcode`\"=\other +\catcode`\~=\other +\catcode`\^=\other +\catcode`\_=\other +\catcode`\|=\other +\catcode`\<=\other +\catcode`\>=\other +\catcode`\+=\other +\catcode`\$=\other +\def\normaldoublequote{"} +\def\normaltilde{~} +\def\normalcaret{^} +\def\normalunderscore{_} +\def\normalverticalbar{|} +\def\normalless{<} +\def\normalgreater{>} +\def\normalplus{+} +\def\normaldollar{$}%$ font-lock fix + +% This macro is used to make a character print one way in \tt +% (where it can probably be output as-is), and another way in other fonts, +% where something hairier probably needs to be done. +% +% #1 is what to print if we are indeed using \tt; #2 is what to print +% otherwise. Since all the Computer Modern typewriter fonts have zero +% interword stretch (and shrink), and it is reasonable to expect all +% typewriter fonts to have this, we can check that font parameter. +% +\def\ifusingtt#1#2{\ifdim \fontdimen3\font=0pt #1\else #2\fi} + +% Same as above, but check for italic font. Actually this also catches +% non-italic slanted fonts since it is impossible to distinguish them from +% italic fonts. But since this is only used by $ and it uses \sl anyway +% this is not a problem. +\def\ifusingit#1#2{\ifdim \fontdimen1\font>0pt #1\else #2\fi} + +% Turn off all special characters except @ +% (and those which the user can use as if they were ordinary). +% Most of these we simply print from the \tt font, but for some, we can +% use math or other variants that look better in normal text. + +\catcode`\"=\active +\def\activedoublequote{{\tt\char34}} +\let"=\activedoublequote +\catcode`\~=\active +\def~{{\tt\char126}} +\chardef\hat=`\^ +\catcode`\^=\active +\def^{{\tt \hat}} + +\catcode`\_=\active +\def_{\ifusingtt\normalunderscore\_} +% Subroutine for the previous macro. +\def\_{\leavevmode \kern.07em \vbox{\hrule width.3em height.1ex}\kern .07em } + +\catcode`\|=\active +\def|{{\tt\char124}} +\chardef \less=`\< +\catcode`\<=\active +\def<{{\tt \less}} +\chardef \gtr=`\> +\catcode`\>=\active +\def>{{\tt \gtr}} +\catcode`\+=\active +\def+{{\tt \char 43}} +\catcode`\$=\active +\def${\ifusingit{{\sl\$}}\normaldollar}%$ font-lock fix + +% If a .fmt file is being used, characters that might appear in a file +% name cannot be active until we have parsed the command line. +% So turn them off again, and have \everyjob (or @setfilename) turn them on. +% \otherifyactive is called near the end of this file. +\def\otherifyactive{\catcode`+=\other \catcode`\_=\other} + +\catcode`\@=0 + +% \backslashcurfont outputs one backslash character in current font, +% as in \char`\\. +\global\chardef\backslashcurfont=`\\ +\global\let\rawbackslashxx=\backslashcurfont % let existing .??s files work + +% \rawbackslash defines an active \ to do \backslashcurfont. +% \otherbackslash defines an active \ to be a literal `\' character with +% catcode other. +{\catcode`\\=\active + @gdef@rawbackslash{@let\=@backslashcurfont} + @gdef@otherbackslash{@let\=@realbackslash} +} + +% \realbackslash is an actual character `\' with catcode other. +{\catcode`\\=\other @gdef@realbackslash{\}} + +% \normalbackslash outputs one backslash in fixed width font. +\def\normalbackslash{{\tt\backslashcurfont}} + +\catcode`\\=\active + +% Used sometimes to turn off (effectively) the active characters +% even after parsing them. +@def@turnoffactive{% + @let"=@normaldoublequote + @let\=@realbackslash + @let~=@normaltilde + @let^=@normalcaret + @let_=@normalunderscore + @let|=@normalverticalbar + @let<=@normalless + @let>=@normalgreater + @let+=@normalplus + @let$=@normaldollar %$ font-lock fix + @unsepspaces +} + +% Same as @turnoffactive except outputs \ as {\tt\char`\\} instead of +% the literal character `\'. (Thus, \ is not expandable when this is in +% effect.) +% +@def@normalturnoffactive{@turnoffactive @let\=@normalbackslash} + +% Make _ and + \other characters, temporarily. +% This is canceled by @fixbackslash. +@otherifyactive + +% If a .fmt file is being used, we don't want the `\input texinfo' to show up. +% That is what \eatinput is for; after that, the `\' should revert to printing +% a backslash. +% +@gdef@eatinput input texinfo{@fixbackslash} +@global@let\ = @eatinput + +% On the other hand, perhaps the file did not have a `\input texinfo'. Then +% the first `\{ in the file would cause an error. This macro tries to fix +% that, assuming it is called before the first `\' could plausibly occur. +% Also back turn on active characters that might appear in the input +% file name, in case not using a pre-dumped format. +% +@gdef@fixbackslash{% + @ifx\@eatinput @let\ = @normalbackslash @fi + @catcode`+=@active + @catcode`@_=@active +} + +% Say @foo, not \foo, in error messages. +@escapechar = `@@ + +% These look ok in all fonts, so just make them not special. +@catcode`@& = @other +@catcode`@# = @other +@catcode`@% = @other + + +@c Local variables: +@c eval: (add-hook 'write-file-hooks 'time-stamp) +@c page-delimiter: "^\\\\message" +@c time-stamp-start: "def\\\\texinfoversion{" +@c time-stamp-format: "%:y-%02m-%02d.%02H" +@c time-stamp-end: "}" +@c End: + +@c vim:sw=2: + +@ignore + arch-tag: e1b36e32-c96e-4135-a41a-0b2efa2ea115 +@end ignore diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/missing b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/missing new file mode 100755 index 00000000..e7ef83a1 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/missing @@ -0,0 +1,360 @@ +#! /bin/sh +# Common stub for a few missing GNU programs while installing. + +scriptversion=2003-09-02.23 + +# Copyright (C) 1996, 1997, 1999, 2000, 2002, 2003 +# Free Software Foundation, Inc. +# Originally by Fran,cois Pinard , 1996. + +# This program is free software; you can redistribute it and/or modify +# it under the terms of the GNU General Public License as published by +# the Free Software Foundation; either version 2, or (at your option) +# any later version. + +# This program is distributed in the hope that it will be useful, +# but WITHOUT ANY WARRANTY; without even the implied warranty of +# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the +# GNU General Public License for more details. + +# You should have received a copy of the GNU General Public License +# along with this program; if not, write to the Free Software +# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA +# 02111-1307, USA. + +# As a special exception to the GNU General Public License, if you +# distribute this file as part of a program that contains a +# configuration script generated by Autoconf, you may include it under +# the same distribution terms that you use for the rest of that program. + +if test $# -eq 0; then + echo 1>&2 "Try \`$0 --help' for more information" + exit 1 +fi + +run=: + +# In the cases where this matters, `missing' is being run in the +# srcdir already. +if test -f configure.ac; then + configure_ac=configure.ac +else + configure_ac=configure.in +fi + +msg="missing on your system" + +case "$1" in +--run) + # Try to run requested program, and just exit if it succeeds. + run= + shift + "$@" && exit 0 + # Exit code 63 means version mismatch. This often happens + # when the user try to use an ancient version of a tool on + # a file that requires a minimum version. In this case we + # we should proceed has if the program had been absent, or + # if --run hadn't been passed. + if test $? = 63; then + run=: + msg="probably too old" + fi + ;; +esac + +# If it does not exist, or fails to run (possibly an outdated version), +# try to emulate it. +case "$1" in + + -h|--h|--he|--hel|--help) + echo "\ +$0 [OPTION]... PROGRAM [ARGUMENT]... + +Handle \`PROGRAM [ARGUMENT]...' for when PROGRAM is missing, or return an +error status if there is no known handling for PROGRAM. + +Options: + -h, --help display this help and exit + -v, --version output version information and exit + --run try to run the given command, and emulate it if it fails + +Supported PROGRAM values: + aclocal touch file \`aclocal.m4' + autoconf touch file \`configure' + autoheader touch file \`config.h.in' + automake touch all \`Makefile.in' files + bison create \`y.tab.[ch]', if possible, from existing .[ch] + flex create \`lex.yy.c', if possible, from existing .c + help2man touch the output file + lex create \`lex.yy.c', if possible, from existing .c + makeinfo touch the output file + tar try tar, gnutar, gtar, then tar without non-portable flags + yacc create \`y.tab.[ch]', if possible, from existing .[ch] + +Send bug reports to ." + ;; + + -v|--v|--ve|--ver|--vers|--versi|--versio|--version) + echo "missing $scriptversion (GNU Automake)" + ;; + + -*) + echo 1>&2 "$0: Unknown \`$1' option" + echo 1>&2 "Try \`$0 --help' for more information" + exit 1 + ;; + + aclocal*) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified \`acinclude.m4' or \`${configure_ac}'. You might want + to install the \`Automake' and \`Perl' packages. Grab them from + any GNU archive site." + touch aclocal.m4 + ;; + + autoconf) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified \`${configure_ac}'. You might want to install the + \`Autoconf' and \`GNU m4' packages. Grab them from any GNU + archive site." + touch configure + ;; + + autoheader) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified \`acconfig.h' or \`${configure_ac}'. You might want + to install the \`Autoconf' and \`GNU m4' packages. Grab them + from any GNU archive site." + files=`sed -n 's/^[ ]*A[CM]_CONFIG_HEADER(\([^)]*\)).*/\1/p' ${configure_ac}` + test -z "$files" && files="config.h" + touch_files= + for f in $files; do + case "$f" in + *:*) touch_files="$touch_files "`echo "$f" | + sed -e 's/^[^:]*://' -e 's/:.*//'`;; + *) touch_files="$touch_files $f.in";; + esac + done + touch $touch_files + ;; + + automake*) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified \`Makefile.am', \`acinclude.m4' or \`${configure_ac}'. + You might want to install the \`Automake' and \`Perl' packages. + Grab them from any GNU archive site." + find . -type f -name Makefile.am -print | + sed 's/\.am$/.in/' | + while read f; do touch "$f"; done + ;; + + autom4te) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is needed, but is $msg. + You might have modified some files without having the + proper tools for further handling them. + You can get \`$1' as part of \`Autoconf' from any GNU + archive site." + + file=`echo "$*" | sed -n 's/.*--output[ =]*\([^ ]*\).*/\1/p'` + test -z "$file" && file=`echo "$*" | sed -n 's/.*-o[ ]*\([^ ]*\).*/\1/p'` + if test -f "$file"; then + touch $file + else + test -z "$file" || exec >$file + echo "#! /bin/sh" + echo "# Created by GNU Automake missing as a replacement of" + echo "# $ $@" + echo "exit 0" + chmod +x $file + exit 1 + fi + ;; + + bison|yacc) + echo 1>&2 "\ +WARNING: \`$1' $msg. You should only need it if + you modified a \`.y' file. You may need the \`Bison' package + in order for those modifications to take effect. You can get + \`Bison' from any GNU archive site." + rm -f y.tab.c y.tab.h + if [ $# -ne 1 ]; then + eval LASTARG="\${$#}" + case "$LASTARG" in + *.y) + SRCFILE=`echo "$LASTARG" | sed 's/y$/c/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" y.tab.c + fi + SRCFILE=`echo "$LASTARG" | sed 's/y$/h/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" y.tab.h + fi + ;; + esac + fi + if [ ! -f y.tab.h ]; then + echo >y.tab.h + fi + if [ ! -f y.tab.c ]; then + echo 'main() { return 0; }' >y.tab.c + fi + ;; + + lex|flex) + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified a \`.l' file. You may need the \`Flex' package + in order for those modifications to take effect. You can get + \`Flex' from any GNU archive site." + rm -f lex.yy.c + if [ $# -ne 1 ]; then + eval LASTARG="\${$#}" + case "$LASTARG" in + *.l) + SRCFILE=`echo "$LASTARG" | sed 's/l$/c/'` + if [ -f "$SRCFILE" ]; then + cp "$SRCFILE" lex.yy.c + fi + ;; + esac + fi + if [ ! -f lex.yy.c ]; then + echo 'main() { return 0; }' >lex.yy.c + fi + ;; + + help2man) + if test -z "$run" && ($1 --version) > /dev/null 2>&1; then + # We have it, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified a dependency of a manual page. You may need the + \`Help2man' package in order for those modifications to take + effect. You can get \`Help2man' from any GNU archive site." + + file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'` + if test -z "$file"; then + file=`echo "$*" | sed -n 's/.*--output=\([^ ]*\).*/\1/p'` + fi + if [ -f "$file" ]; then + touch $file + else + test -z "$file" || exec >$file + echo ".ab help2man is required to generate this page" + exit 1 + fi + ;; + + makeinfo) + if test -z "$run" && (makeinfo --version) > /dev/null 2>&1; then + # We have makeinfo, but it failed. + exit 1 + fi + + echo 1>&2 "\ +WARNING: \`$1' is $msg. You should only need it if + you modified a \`.texi' or \`.texinfo' file, or any other file + indirectly affecting the aspect of the manual. The spurious + call might also be the consequence of using a buggy \`make' (AIX, + DU, IRIX). You might want to install the \`Texinfo' package or + the \`GNU make' package. Grab either from any GNU archive site." + file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'` + if test -z "$file"; then + file=`echo "$*" | sed 's/.* \([^ ]*\) *$/\1/'` + file=`sed -n '/^@setfilename/ { s/.* \([^ ]*\) *$/\1/; p; q; }' $file` + fi + touch $file + ;; + + tar) + shift + if test -n "$run"; then + echo 1>&2 "ERROR: \`tar' requires --run" + exit 1 + fi + + # We have already tried tar in the generic part. + # Look for gnutar/gtar before invocation to avoid ugly error + # messages. + if (gnutar --version > /dev/null 2>&1); then + gnutar "$@" && exit 0 + fi + if (gtar --version > /dev/null 2>&1); then + gtar "$@" && exit 0 + fi + firstarg="$1" + if shift; then + case "$firstarg" in + *o*) + firstarg=`echo "$firstarg" | sed s/o//` + tar "$firstarg" "$@" && exit 0 + ;; + esac + case "$firstarg" in + *h*) + firstarg=`echo "$firstarg" | sed s/h//` + tar "$firstarg" "$@" && exit 0 + ;; + esac + fi + + echo 1>&2 "\ +WARNING: I can't seem to be able to run \`tar' with the given arguments. + You may want to install GNU tar or Free paxutils, or check the + command line arguments." + exit 1 + ;; + + *) + echo 1>&2 "\ +WARNING: \`$1' is needed, and is $msg. + You might have modified some files without having the + proper tools for further handling them. Check the \`README' file, + it often tells you about the needed prerequisites for installing + this package. You may also peek at any GNU archive site, in case + some other package would contain this missing \`$1' program." + exit 1 + ;; +esac + +exit 0 + +# Local variables: +# eval: (add-hook 'write-file-hooks 'time-stamp) +# time-stamp-start: "scriptversion=" +# time-stamp-format: "%:y-%02m-%02d.%02H" +# time-stamp-end: "$" +# End: diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/stamp-h1 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/stamp-h1 new file mode 100755 index 00000000..4547fe1b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/stamp-h1 @@ -0,0 +1 @@ +timestamp for config.h diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/vienna13.par b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/vienna13.par new file mode 100755 index 00000000..7df1b601 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/vienna13.par @@ -0,0 +1,11705 @@ +## RNAfold parameter file + +# stack_energies +/* CG GC GU UG AU UA @ */ + -200 -290 -190 -120 -170 -180 0 + -290 -340 -210 -140 -210 -230 0 + -190 -210 150 -40 -100 -110 0 + -120 -140 -40 -20 -50 -80 0 + -170 -210 -100 -50 -90 -90 0 + -180 -230 -110 -80 -90 -110 0 + 0 0 0 0 0 0 0 + +# stack_enthalpies +/* CG GC GU UG AU UA @ */ + -800 -1220 -1120 -310 -760 -1050 0 + -1220 -1420 -950 -630 -1020 -1330 0 + -1120 -950 -1605 -2000 -400 -1360 0 + -310 -630 -2000 -1110 -270 -850 0 + -760 -1020 -400 -270 -570 -660 0 + -1050 -1330 -1360 -850 -660 -810 0 + 0 0 0 0 0 0 0 + +# mismatch_hairpin + 0 0 0 0 0 + DEF -140 -200 -210 -190 + DEF -100 -110 -100 -80 + DEF -210 -190 -140 -190 + DEF -140 -150 -140 -120 + 0 0 0 0 0 + DEF -110 -130 -200 -130 + DEF -110 -60 -60 -50 + DEF -230 -150 -140 -150 + DEF -80 -80 -80 -70 + 0 0 0 0 0 + DEF -80 -100 -170 -100 + DEF -70 -70 -70 -70 + DEF -150 -100 -100 -100 + DEF -80 -80 -80 -80 + 0 0 0 0 0 + DEF -120 -140 -200 -140 + DEF -90 -90 -70 -70 + DEF -200 -140 -130 -140 + DEF -90 -110 -90 -90 + 0 0 0 0 0 + DEF -80 -100 -170 -100 + DEF -70 -70 -70 -70 + DEF -150 -100 -100 -100 + DEF -80 -80 -80 -80 + 0 0 0 0 0 + DEF -100 -80 -180 -90 + DEF -70 -60 -30 -50 + DEF -180 -90 -120 -90 + DEF -30 -60 -30 -50 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + +# mismatch_interior + 0 0 0 0 0 + DEF -150 -150 -270 -190 + DEF -150 -150 -100 -150 + DEF -270 -190 -150 -190 + DEF -140 -150 -140 -250 + 0 0 0 0 0 + DEF -150 -150 -270 -130 + DEF -150 -150 -60 -150 + DEF -270 -150 -150 -150 + DEF -80 -150 -80 -250 + 0 0 0 0 0 + DEF -150 -150 -270 -130 + DEF -150 -150 -60 -150 + DEF -270 -150 -150 -150 + DEF -80 -150 -80 -250 + 0 0 0 0 0 + DEF -100 -100 -220 -40 + DEF -100 -100 20 -100 + DEF -220 -40 -100 -40 + DEF 20 -100 20 -200 + 0 0 0 0 0 + DEF -100 -100 -220 -50 + DEF -100 -100 -20 -100 + DEF -220 -50 -100 -50 + DEF -30 -100 -30 -200 + 0 0 0 0 0 + DEF -100 -100 -220 -40 + DEF -100 -100 20 -100 + DEF -220 -40 -100 -40 + DEF 20 -100 20 -200 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + +# mismatch_multi + -50 -70 -80 -50 -50 + -170 -190 -200 -170 -170 + -80 -100 -110 -80 -80 + -170 -190 -200 -170 -170 + -120 -140 -150 -120 -120 + -50 -100 -80 -70 -60 + -110 -160 -140 -130 -120 + -40 -90 -70 -60 -50 + -130 -180 -160 -150 -140 + -60 -110 -90 -80 -70 + -50 -70 -70 -70 -70 + -80 -100 -100 -100 -100 + -50 -70 -70 -70 -70 + -80 -100 -100 -100 -100 + -60 -80 -80 -80 -80 + -50 -70 -70 -70 -70 + -120 -140 -140 -140 -140 + -50 -70 -70 -70 -70 + -120 -140 -140 -140 -140 + -70 -90 -90 -90 -90 + -50 -80 -60 -70 -70 + -80 -110 -90 -100 -100 + -50 -80 -60 -70 -70 + -80 -110 -90 -100 -100 + -60 -90 -70 -80 -80 + -50 -80 -80 -90 -70 + -70 -100 -100 -110 -90 + -10 -40 -40 -50 -30 + -70 -100 -100 -110 -90 + -10 -40 -40 -50 -30 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + 0 0 0 0 0 + +# mismatch_enthalpies + 0 0 0 0 0 + DEF -1030 -950 -1030 -1030 + DEF -520 -450 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-130 -60 + DEF -170 -80 -170 -120 + DEF -120 -50 -120 -70 + DEF -80 -50 -80 -60 + DEF -70 -10 -70 -10 + DEF -80 -50 -80 -60 + 0 0 0 0 0 + +# dangle5_enthalpies +/* @ A C G U */ + INF INF INF INF INF + 0 -240 330 80 -140 + 0 -160 70 -460 -40 + 0 160 220 70 310 + 0 -150 510 10 100 + 0 160 220 70 310 + 0 -50 690 -60 -60 + 0 0 0 0 0 + +# dangle3_enthalpies +/* @ A C G U */ + INF INF INF INF INF + 0 -740 -280 -640 -360 + 0 -900 -410 -860 -750 + 0 -740 -240 -720 -490 + 0 -490 -90 -550 -230 + 0 -570 -70 -580 -220 + 0 -490 -90 -550 -230 + 0 0 0 0 0 + +# int11_energies +/* GC..GC */ + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 +/* GC..CG */ + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 +/* GC..GU */ + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 +/* GC..UG */ + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 + 80 80 80 80 80 +/* GC..AU */ + 80 80 80 80 80 + 80 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-1029 + -769 -1748 -1668 -1748 -1748 + -529 -1508 -1428 -1508 -1508 + -709 -1688 -1608 -1688 -1688 + -599 -1578 -1498 -1578 -1578 +/* CG.C..UG */ + DEF -519 -449 -519 -669 + -839 -1308 -1238 -1308 -1458 + -529 -998 -928 -998 -1148 + -859 -1328 -1258 -1328 -1478 + -489 -958 -888 -958 -1108 +/* CG.G..UG */ + DEF -939 -939 -939 -939 + -1009 -1898 -1898 -1898 -1898 + -409 -1298 -1298 -1298 -1298 + -969 -1858 -1858 -1858 -1858 + -599 -1488 -1488 -1488 -1488 +/* CG.U..UG */ + DEF -809 -739 -809 -859 + -859 -1618 -1548 -1618 -1668 + -529 -1288 -1218 -1288 -1338 + -859 -1618 -1548 -1618 -1668 + -409 -1168 -1098 -1168 -1218 +/* CG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* CG.A..AU */ + DEF -1029 -949 -1029 -1029 + -479 -1458 -1378 -1458 -1458 + -309 -1288 -1208 -1288 -1288 + -389 -1368 -1288 -1368 -1368 + -379 -1358 -1278 -1358 -1358 +/* CG.C..AU */ + DEF -519 -449 -519 -669 + -649 -1118 -1048 -1118 -1268 + -289 -758 -688 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0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..AU */ + DEF -519 -879 -559 -879 + -479 -948 -1308 -988 -1308 + -309 -778 -1138 -818 -1138 + -389 -858 -1218 -898 -1218 + -379 -848 -1208 -888 -1208 +/* GC.C..AU */ + DEF -719 -309 -309 -389 + -649 -1318 -908 -908 -988 + -289 -958 -548 -548 -628 + -739 -1408 -998 -998 -1078 + -379 -1048 -638 -638 -718 +/* GC.G..AU */ + DEF -709 -739 -619 -739 + -649 -1308 -1338 -1218 -1338 + -289 -948 -978 -858 -978 + -739 -1398 -1428 -1308 -1428 + -379 -1038 -1068 -948 -1068 +/* GC.U..AU */ + DEF -499 -499 -499 -569 + -649 -1098 -1098 -1098 -1168 + -289 -738 -738 -738 -808 + -739 -1188 -1188 -1188 -1258 + -379 -828 -828 -828 -898 +/* GC.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GC.A..UA */ + DEF -519 -879 -559 -879 + -449 -918 -1278 -958 -1278 + -479 -948 -1308 -988 -1308 + -429 -898 -1258 -938 -1258 + -329 -798 -1158 -838 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-789 + -100 -759 -789 -669 -789 + -100 -759 -789 -669 -789 +/* GC.U.. @ */ + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 + -100 -549 -549 -549 -619 +/* GU.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..CG */ + DEF -429 -599 -599 -599 + -1079 -1458 -1628 -1628 -1628 + -569 -948 -1118 -1118 -1118 + -989 -1368 -1538 -1538 -1538 + -859 -1238 -1408 -1408 -1408 +/* GU.C..CG */ + DEF -259 -239 -239 -239 + -999 -1208 -1188 -1188 -1188 + -499 -708 -688 -688 -688 + -989 -1198 -1178 -1178 -1178 + -789 -998 -978 -978 -978 +/* GU.G..CG */ + DEF -339 -689 -689 -689 + -1079 -1368 -1718 -1718 -1718 + -569 -858 -1208 -1208 -1208 + -989 -1278 -1628 -1628 -1628 + -859 -1148 -1498 -1498 -1498 +/* GU.U..CG */ + DEF -329 -329 -329 -329 + -1079 -1358 -1358 -1358 -1358 + -719 -998 -998 -998 -998 + -989 -1268 -1268 -1268 -1268 + -909 -1188 -1188 -1188 -1188 +/* GU.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GC */ + DEF -429 -599 -599 -599 + -569 -948 -1118 -1118 -1118 + -769 -1148 -1318 -1318 -1318 + -759 -1138 -1308 -1308 -1308 + -549 -928 -1098 -1098 -1098 +/* GU.C..GC */ + DEF -259 -239 -239 -239 + -929 -1138 -1118 -1118 -1118 + -359 -568 -548 -548 -548 + -789 -998 -978 -978 -978 + -549 -758 -738 -738 -738 +/* GU.G..GC */ + DEF -339 -689 -689 -689 + -609 -898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* GU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* GU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* GU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 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-289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 + -100 -309 -289 -289 -289 +/* GU.G.. @ */ + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 + -100 -389 -739 -739 -739 +/* GU.U.. @ */ + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 + -100 -379 -379 -379 -379 +/* UG.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..CG */ + DEF -719 -789 -959 -809 + -1079 -1748 -1818 -1988 -1838 + -569 -1238 -1308 -1478 -1328 + -989 -1658 -1728 -1898 -1748 + -859 -1528 -1598 -1768 -1618 +/* UG.C..CG */ + DEF -479 -479 -359 -479 + -999 -1428 -1428 -1308 -1428 + -499 -928 -928 -808 -928 + -989 -1418 -1418 -1298 -1418 + -789 -1218 -1218 -1098 -1218 +/* UG.G..CG */ + DEF -659 -809 -919 -809 + -1079 -1688 -1838 -1948 -1838 + -569 -1178 -1328 -1438 -1328 + -989 -1598 -1748 -1858 -1748 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DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..GU */ + DEF -719 -789 -959 -809 + -479 -1148 -1218 -1388 -1238 + -309 -978 -1048 -1218 -1068 + -389 -1058 -1128 -1298 -1148 + -379 -1048 -1118 -1288 -1138 +/* UG.C..GU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..GU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..GU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UG */ + DEF -719 -789 -959 -809 + -769 -1438 -1508 -1678 -1528 + -529 -1198 -1268 -1438 -1288 + -709 -1378 -1448 -1618 -1468 + -599 -1268 -1338 -1508 -1358 +/* UG.C..UG */ + DEF -479 -479 -359 -479 + -839 -1268 -1268 -1148 -1268 + -529 -958 -958 -838 -958 + -859 -1288 -1288 -1168 -1288 + -489 -918 -918 -798 -918 +/* UG.G..UG */ + DEF -659 -809 -919 -809 + -1009 -1618 -1768 -1878 -1768 + -409 -1018 -1168 -1278 -1168 + -969 -1578 -1728 -1838 -1728 + -599 -1208 -1358 -1468 -1358 +/* UG.U..UG */ + DEF -549 -439 -549 -359 + -859 -1358 -1248 -1358 -1168 + -529 -1028 -918 -1028 -838 + -859 -1358 -1248 -1358 -1168 + -409 -908 -798 -908 -718 +/* UG.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..AU */ + DEF -719 -789 -959 -809 + -479 -1148 -1218 -1388 -1238 + -309 -978 -1048 -1218 -1068 + -389 -1058 -1128 -1298 -1148 + -379 -1048 -1118 -1288 -1138 +/* UG.C..AU */ + DEF -479 -479 -359 -479 + -649 -1078 -1078 -958 -1078 + -289 -718 -718 -598 -718 + -739 -1168 -1168 -1048 -1168 + -379 -808 -808 -688 -808 +/* UG.G..AU */ + DEF -659 -809 -919 -809 + -649 -1258 -1408 -1518 -1408 + -289 -898 -1048 -1158 -1048 + -739 -1348 -1498 -1608 -1498 + -379 -988 -1138 -1248 -1138 +/* UG.U..AU */ + DEF -549 -439 -549 -359 + -649 -1148 -1038 -1148 -958 + -289 -788 -678 -788 -598 + -739 -1238 -1128 -1238 -1048 + -379 -878 -768 -878 -688 +/* UG.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A..UA */ + DEF -719 -789 -959 -809 + -449 -1118 -1188 -1358 -1208 + -479 -1148 -1218 -1388 -1238 + -429 -1098 -1168 -1338 -1188 + -329 -998 -1068 -1238 -1088 +/* UG.C..UA */ + DEF -479 -479 -359 -479 + -679 -1108 -1108 -988 -1108 + -559 -988 -988 -868 -988 + -729 -1158 -1158 -1038 -1158 + -189 -618 -618 -498 -618 +/* UG.G..UA */ + DEF -659 -809 -919 -809 + -939 -1548 -1698 -1808 -1698 + -249 -858 -1008 -1118 -1008 + -939 -1548 -1698 -1808 -1698 + -329 -938 -1088 -1198 -1088 +/* UG.U..UA */ + DEF -549 -439 -549 -359 + -639 -1138 -1028 -1138 -948 + -229 -728 -618 -728 -538 + -729 -1228 -1118 -1228 -1038 + -190 -689 -579 -689 -499 +/* UG.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UG.A.. @ */ + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 + -100 -769 -839 -1009 -859 +/* UG.C.. @ */ + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 + -100 -529 -529 -409 -529 +/* UG.G.. @ */ + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 + -100 -709 -859 -969 -859 +/* UG.U.. @ */ + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 + -100 -599 -489 -599 -409 +/* AU.@..CG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..CG */ + DEF -429 -599 -599 -599 + -1079 -1458 -1628 -1628 -1628 + -569 -948 -1118 -1118 -1118 + -989 -1368 -1538 -1538 -1538 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-898 -1248 -1248 -1248 + -359 -648 -998 -998 -998 + -669 -958 -1308 -1308 -1308 + -549 -838 -1188 -1188 -1188 +/* AU.U..GC */ + DEF -329 -329 -329 -329 + -929 -1208 -1208 -1208 -1208 + -439 -718 -718 -718 -718 + -789 -1068 -1068 -1068 -1068 + -619 -898 -898 -898 -898 +/* AU.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..GU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 -938 + -379 -758 -928 -928 -928 +/* AU.C..GU */ + DEF -259 -239 -239 -239 + -649 -858 -838 -838 -838 + -289 -498 -478 -478 -478 + -739 -948 -928 -928 -928 + -379 -588 -568 -568 -568 +/* AU.G..GU */ + DEF -339 -689 -689 -689 + -649 -938 -1288 -1288 -1288 + -289 -578 -928 -928 -928 + -739 -1028 -1378 -1378 -1378 + -379 -668 -1018 -1018 -1018 +/* AU.U..GU */ + DEF -329 -329 -329 -329 + -649 -928 -928 -928 -928 + -289 -568 -568 -568 -568 + -739 -1018 -1018 -1018 -1018 + -379 -658 -658 -658 -658 +/* AU.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..UG */ + DEF -429 -599 -599 -599 + -769 -1148 -1318 -1318 -1318 + -529 -908 -1078 -1078 -1078 + -709 -1088 -1258 -1258 -1258 + -599 -978 -1148 -1148 -1148 +/* AU.C..UG */ + DEF -259 -239 -239 -239 + -839 -1048 -1028 -1028 -1028 + -529 -738 -718 -718 -718 + -859 -1068 -1048 -1048 -1048 + -489 -698 -678 -678 -678 +/* AU.G..UG */ + DEF -339 -689 -689 -689 + -1009 -1298 -1648 -1648 -1648 + -409 -698 -1048 -1048 -1048 + -969 -1258 -1608 -1608 -1608 + -599 -888 -1238 -1238 -1238 +/* AU.U..UG */ + DEF -329 -329 -329 -329 + -859 -1138 -1138 -1138 -1138 + -529 -808 -808 -808 -808 + -859 -1138 -1138 -1138 -1138 + -409 -688 -688 -688 -688 +/* AU.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* AU.A..AU */ + DEF -429 -599 -599 -599 + -479 -858 -1028 -1028 -1028 + -309 -688 -858 -858 -858 + -389 -768 -938 -938 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DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..CG */ + DEF -399 -629 -889 -589 + -1079 -1428 -1658 -1918 -1618 + -569 -918 -1148 -1408 -1108 + -989 -1338 -1568 -1828 -1528 + -859 -1208 -1438 -1698 -1398 +/* UA.C..CG */ + DEF -429 -509 -199 -179 + -999 -1378 -1458 -1148 -1128 + -499 -878 -958 -648 -628 + -989 -1368 -1448 -1138 -1118 + -789 -1168 -1248 -938 -918 +/* UA.G..CG */ + DEF -379 -679 -889 -679 + -1079 -1408 -1708 -1918 -1708 + -569 -898 -1198 -1408 -1198 + -989 -1318 -1618 -1828 -1618 + -859 -1188 -1488 -1698 -1488 +/* UA.U..CG */ + DEF -279 -139 -279 -140 + -1079 -1308 -1168 -1308 -1169 + -719 -948 -808 -948 -809 + -989 -1218 -1078 -1218 -1079 + -909 -1138 -998 -1138 -999 +/* UA.@..GC */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GC */ + DEF -399 -629 -889 -589 + -569 -918 -1148 -1408 -1108 + -769 -1118 -1348 -1608 -1308 + -759 -1108 -1338 -1598 -1298 + -549 -898 -1128 -1388 -1088 +/* UA.C..GC */ + DEF -429 -509 -199 -179 + -929 -1308 -1388 -1078 -1058 + -359 -738 -818 -508 -488 + -789 -1168 -1248 -938 -918 + -549 -928 -1008 -698 -678 +/* UA.G..GC */ + DEF -379 -679 -889 -679 + -609 -938 -1238 -1448 -1238 + -359 -688 -988 -1198 -988 + -669 -998 -1298 -1508 -1298 + -549 -878 -1178 -1388 -1178 +/* UA.U..GC */ + DEF -279 -139 -279 -140 + -929 -1158 -1018 -1158 -1019 + -439 -668 -528 -668 -529 + -789 -1018 -878 -1018 -879 + -619 -848 -708 -848 -709 +/* UA.@..GU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..GU */ + DEF -399 -629 -889 -589 + -479 -828 -1058 -1318 -1018 + -309 -658 -888 -1148 -848 + -389 -738 -968 -1228 -928 + -379 -728 -958 -1218 -918 +/* UA.C..GU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..GU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..GU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 +/* UA.@..UG */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..UG */ + DEF -399 -629 -889 -589 + -769 -1118 -1348 -1608 -1308 + -529 -878 -1108 -1368 -1068 + -709 -1058 -1288 -1548 -1248 + -599 -948 -1178 -1438 -1138 +/* UA.C..UG */ + DEF -429 -509 -199 -179 + -839 -1218 -1298 -988 -968 + -529 -908 -988 -678 -658 + -859 -1238 -1318 -1008 -988 + -489 -868 -948 -638 -618 +/* UA.G..UG */ + DEF -379 -679 -889 -679 + -1009 -1338 -1638 -1848 -1638 + -409 -738 -1038 -1248 -1038 + -969 -1298 -1598 -1808 -1598 + -599 -928 -1228 -1438 -1228 +/* UA.U..UG */ + DEF -279 -139 -279 -140 + -859 -1088 -948 -1088 -949 + -529 -758 -618 -758 -619 + -859 -1088 -948 -1088 -949 + -409 -638 -498 -638 -499 +/* UA.@..AU */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..AU */ + DEF -399 -629 -889 -589 + -479 -828 -1058 -1318 -1018 + -309 -658 -888 -1148 -848 + -389 -738 -968 -1228 -928 + -379 -728 -958 -1218 -918 +/* UA.C..AU */ + DEF -429 -509 -199 -179 + -649 -1028 -1108 -798 -778 + -289 -668 -748 -438 -418 + -739 -1118 -1198 -888 -868 + -379 -758 -838 -528 -508 +/* UA.G..AU */ + DEF -379 -679 -889 -679 + -649 -978 -1278 -1488 -1278 + -289 -618 -918 -1128 -918 + -739 -1068 -1368 -1578 -1368 + -379 -708 -1008 -1218 -1008 +/* UA.U..AU */ + DEF -279 -139 -279 -140 + -649 -878 -738 -878 -739 + -289 -518 -378 -518 -379 + -739 -968 -828 -968 -829 + -379 -608 -468 -608 -469 +/* UA.@..UA */ + 0 0 0 0 0 + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A..UA */ + DEF -399 -629 -889 -589 + -449 -798 -1028 -1288 -988 + -479 -828 -1058 -1318 -1018 + -429 -778 -1008 -1268 -968 + -329 -678 -908 -1168 -868 +/* UA.C..UA */ + DEF -429 -509 -199 -179 + -679 -1058 -1138 -828 -808 + -559 -938 -1018 -708 -688 + -729 -1108 -1188 -878 -858 + -189 -568 -648 -338 -318 +/* UA.G..UA */ + DEF -379 -679 -889 -679 + -939 -1268 -1568 -1778 -1568 + -249 -578 -878 -1088 -878 + -939 -1268 -1568 -1778 -1568 + -329 -658 -958 -1168 -958 +/* UA.U..UA */ + DEF -279 -139 -279 -140 + -639 -868 -728 -868 -729 + -229 -458 -318 -458 -319 + -729 -958 -818 -958 -819 + -190 -419 -279 -419 -280 +/* UA.@.. @ */ + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF + DEF DEF DEF DEF DEF +/* UA.A.. @ */ + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 + -100 -449 -679 -939 -639 +/* UA.C.. @ */ + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 + -100 -479 -559 -249 -229 +/* UA.G.. @ */ + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + -100 -429 -729 -939 -729 + 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CG.GG..AU */ + -1538 -1538 -1538 -1538 + -1178 -1178 -1178 -1178 + -1628 -1628 -1628 -1628 + -1268 -1268 -1268 -1268 +/* CG.GU..AU */ + -1538 -1538 -1538 -1538 + -1178 -1178 -1178 -1178 + -1628 -1628 -1628 -1628 + -1268 -1268 -1268 -1268 +/* CG.UA..AU */ + -1238 -1168 -1238 -1288 + -1068 -998 -1068 -1118 + -1148 -1078 -1148 -1198 + -1138 -1068 -1138 -1188 +/* CG.UC..AU */ + -1408 -1338 -1408 -1458 + -1048 -978 -1048 -1098 + -1498 -1428 -1498 -1548 + -1138 -1068 -1138 -1188 +/* CG.UG..AU */ + -1408 -1338 -1408 -1458 + -1048 -978 -1048 -1098 + -1498 -1428 -1498 -1548 + -1138 -1068 -1138 -1188 +/* CG.UU..AU */ + -1408 -1338 -1408 -1458 + -1048 -978 -1048 -1098 + -1498 -1428 -1498 -1548 + -1138 -1068 -1138 -1188 +/* CG.AA..UA */ + -1428 -1348 -1428 -1428 + -1458 -1378 -1458 -1458 + -1408 -1328 -1408 -1408 + -1308 -1228 -1308 -1308 +/* CG.AC..UA */ + -1658 -1578 -1658 -1658 + -1538 -1458 -1538 -1538 + -1708 -1628 -1708 -1708 + -1168 -1088 -1168 -1168 +/* CG.AG..UA */ + -1918 -1838 -1918 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-909 + -859 -789 -859 -909 +/* CG.UC.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* CG.UG.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* CG.UU.. @ */ + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 + -859 -789 -859 -909 +/* GC.AA..CG */ + -1548 -1908 -1588 -1908 + -1038 -1398 -1078 -1398 + -1458 -1818 -1498 -1818 + -1328 -1688 -1368 -1688 +/* GC.AC..CG */ + -1468 -1828 -1508 -1828 + -968 -1328 -1008 -1328 + -1458 -1818 -1498 -1818 + -1258 -1618 -1298 -1618 +/* GC.AG..CG */ + -1548 -1908 -1588 -1908 + -1038 -1398 -1078 -1398 + -1458 -1818 -1498 -1818 + -1328 -1688 -1368 -1688 +/* GC.AU..CG */ + -1548 -1908 -1588 -1908 + -1188 -1548 -1228 -1548 + -1458 -1818 -1498 -1818 + -1378 -1738 -1418 -1738 +/* GC.CA..CG */ + -1748 -1338 -1338 -1418 + -1238 -828 -828 -908 + -1658 -1248 -1248 -1328 + -1528 -1118 -1118 -1198 +/* GC.CC..CG */ + -1668 -1258 -1258 -1338 + -1168 -758 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-1238 -1238 -1238 -1308 +/* GC.UG..CG */ + -1528 -1528 -1528 -1598 + -1018 -1018 -1018 -1088 + -1438 -1438 -1438 -1508 + -1308 -1308 -1308 -1378 +/* GC.UU..CG */ + -1528 -1528 -1528 -1598 + -1168 -1168 -1168 -1238 + -1438 -1438 -1438 -1508 + -1358 -1358 -1358 -1428 +/* GC.AA..GC */ + -1038 -1398 -1078 -1398 + -1238 -1598 -1278 -1598 + -1228 -1588 -1268 -1588 + -1018 -1378 -1058 -1378 +/* GC.AC..GC */ + -1398 -1758 -1438 -1758 + -828 -1188 -868 -1188 + -1258 -1618 -1298 -1618 + -1018 -1378 -1058 -1378 +/* GC.AG..GC */ + -1078 -1438 -1118 -1438 + -828 -1188 -868 -1188 + -1138 -1498 -1178 -1498 + -1018 -1378 -1058 -1378 +/* GC.AU..GC */ + -1398 -1758 -1438 -1758 + -908 -1268 -948 -1268 + -1258 -1618 -1298 -1618 + -1088 -1448 -1128 -1448 +/* GC.CA..GC */ + -1238 -828 -828 -908 + -1438 -1028 -1028 -1108 + -1428 -1018 -1018 -1098 + -1218 -808 -808 -888 +/* GC.CC..GC */ + -1598 -1188 -1188 -1268 + -1028 -618 -618 -698 + -1458 -1048 -1048 -1128 + -1218 -808 -808 -888 +/* GC.CG..GC */ + -1278 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-1408 -998 -998 -1078 + -1048 -638 -638 -718 +/* GC.GA..GU */ + -1138 -1168 -1048 -1168 + -968 -998 -878 -998 + -1048 -1078 -958 -1078 + -1038 -1068 -948 -1068 +/* GC.GC..GU */ + -1308 -1338 -1218 -1338 + -948 -978 -858 -978 + -1398 -1428 -1308 -1428 + -1038 -1068 -948 -1068 +/* GC.GG..GU */ + -1308 -1338 -1218 -1338 + -948 -978 -858 -978 + -1398 -1428 -1308 -1428 + -1038 -1068 -948 -1068 +/* GC.GU..GU */ + -1308 -1338 -1218 -1338 + -948 -978 -858 -978 + -1398 -1428 -1308 -1428 + -1038 -1068 -948 -1068 +/* GC.UA..GU */ + -928 -928 -928 -998 + -758 -758 -758 -828 + -838 -838 -838 -908 + -828 -828 -828 -898 +/* GC.UC..GU */ + -1098 -1098 -1098 -1168 + -738 -738 -738 -808 + -1188 -1188 -1188 -1258 + -828 -828 -828 -898 +/* GC.UG..GU */ + -1098 -1098 -1098 -1168 + -738 -738 -738 -808 + -1188 -1188 -1188 -1258 + -828 -828 -828 -898 +/* GC.UU..GU */ + -1098 -1098 -1098 -1168 + -738 -738 -738 -808 + -1188 -1188 -1188 -1258 + -828 -828 -828 -898 +/* GC.AA..UG */ + -1238 -1598 -1278 -1598 + -998 -1358 -1038 -1358 + -1178 -1538 -1218 -1538 + -1068 -1428 -1108 -1428 +/* GC.AC..UG */ + -1308 -1668 -1348 -1668 + -998 -1358 -1038 -1358 + -1328 -1688 -1368 -1688 + -958 -1318 -998 -1318 +/* GC.AG..UG */ + -1478 -1838 -1518 -1838 + -878 -1238 -918 -1238 + -1438 -1798 -1478 -1798 + -1068 -1428 -1108 -1428 +/* GC.AU..UG */ + -1328 -1688 -1368 -1688 + -998 -1358 -1038 -1358 + -1328 -1688 -1368 -1688 + -878 -1238 -918 -1238 +/* GC.CA..UG */ + -1438 -1028 -1028 -1108 + -1198 -788 -788 -868 + -1378 -968 -968 -1048 + -1268 -858 -858 -938 +/* GC.CC..UG */ + -1508 -1098 -1098 -1178 + -1198 -788 -788 -868 + -1528 -1118 -1118 -1198 + -1158 -748 -748 -828 +/* GC.CG..UG */ + -1678 -1268 -1268 -1348 + -1078 -668 -668 -748 + -1638 -1228 -1228 -1308 + -1268 -858 -858 -938 +/* GC.CU..UG */ + -1528 -1118 -1118 -1198 + -1198 -788 -788 -868 + -1528 -1118 -1118 -1198 + -1078 -668 -668 -748 +/* GC.GA..UG */ + -1428 -1458 -1338 -1458 + -1188 -1218 -1098 -1218 + -1368 -1398 -1278 -1398 + -1258 -1288 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GC.AU..UA */ + -1108 -1468 -1148 -1468 + -698 -1058 -738 -1058 + -1198 -1558 -1238 -1558 + -659 -1019 -699 -1019 +/* GC.CA..UA */ + -1118 -708 -708 -788 + -1148 -738 -738 -818 + -1098 -688 -688 -768 + -998 -588 -588 -668 +/* GC.CC..UA */ + -1348 -938 -938 -1018 + -1228 -818 -818 -898 + -1398 -988 -988 -1068 + -858 -448 -448 -528 +/* GC.CG..UA */ + -1608 -1198 -1198 -1278 + -918 -508 -508 -588 + -1608 -1198 -1198 -1278 + -998 -588 -588 -668 +/* GC.CU..UA */ + -1308 -898 -898 -978 + -898 -488 -488 -568 + -1398 -988 -988 -1068 + -859 -449 -449 -529 +/* GC.GA..UA */ + -1108 -1138 -1018 -1138 + -1138 -1168 -1048 -1168 + -1088 -1118 -998 -1118 + -988 -1018 -898 -1018 +/* GC.GC..UA */ + -1338 -1368 -1248 -1368 + -1218 -1248 -1128 -1248 + -1388 -1418 -1298 -1418 + -848 -878 -758 -878 +/* GC.GG..UA */ + -1598 -1628 -1508 -1628 + -908 -938 -818 -938 + -1598 -1628 -1508 -1628 + -988 -1018 -898 -1018 +/* GC.GU..UA */ + -1298 -1328 -1208 -1328 + -888 -918 -798 -918 + -1388 -1418 -1298 -1418 + -849 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AU.UA..CG */ + -1358 -1358 -1358 -1358 + -848 -848 -848 -848 + -1268 -1268 -1268 -1268 + -1138 -1138 -1138 -1138 +/* AU.UC..CG */ + -1278 -1278 -1278 -1278 + -778 -778 -778 -778 + -1268 -1268 -1268 -1268 + -1068 -1068 -1068 -1068 +/* AU.UG..CG */ + -1358 -1358 -1358 -1358 + -848 -848 -848 -848 + -1268 -1268 -1268 -1268 + -1138 -1138 -1138 -1138 +/* AU.UU..CG */ + -1358 -1358 -1358 -1358 + -998 -998 -998 -998 + -1268 -1268 -1268 -1268 + -1188 -1188 -1188 -1188 +/* AU.AA..GC */ + -948 -1118 -1118 -1118 + -1148 -1318 -1318 -1318 + -1138 -1308 -1308 -1308 + -928 -1098 -1098 -1098 +/* AU.AC..GC */ + -1308 -1478 -1478 -1478 + -738 -908 -908 -908 + -1168 -1338 -1338 -1338 + -928 -1098 -1098 -1098 +/* AU.AG..GC */ + -988 -1158 -1158 -1158 + -738 -908 -908 -908 + -1048 -1218 -1218 -1218 + -928 -1098 -1098 -1098 +/* AU.AU..GC */ + -1308 -1478 -1478 -1478 + -818 -988 -988 -988 + -1168 -1338 -1338 -1338 + -998 -1168 -1168 -1168 +/* AU.CA..GC */ + -778 -758 -758 -758 + -978 -958 -958 -958 + -968 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-758 -758 -758 -758 + -708 -708 -708 -708 + -608 -608 -608 -608 +/* AU.UC..UA */ + -958 -958 -958 -958 + -838 -838 -838 -838 + -1008 -1008 -1008 -1008 + -468 -468 -468 -468 +/* AU.UG..UA */ + -1218 -1218 -1218 -1218 + -528 -528 -528 -528 + -1218 -1218 -1218 -1218 + -608 -608 -608 -608 +/* AU.UU..UA */ + -918 -918 -918 -918 + -508 -508 -508 -508 + -1008 -1008 -1008 -1008 + -469 -469 -469 -469 +/* AU.AA.. @ */ + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 +/* AU.AC.. @ */ + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 +/* AU.AG.. @ */ + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 +/* AU.AU.. @ */ + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 + -479 -649 -649 -649 +/* AU.CA.. @ */ + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 +/* AU.CC.. @ */ + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 +/* AU.CG.. @ */ + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 +/* AU.CU.. @ */ + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 + -309 -289 -289 -289 +/* AU.GA.. @ */ + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 +/* AU.GC.. @ */ + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 +/* AU.GG.. @ */ + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 +/* AU.GU.. @ */ + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 + -389 -739 -739 -739 +/* AU.UA.. @ */ + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 +/* AU.UC.. @ */ + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 +/* AU.UG.. @ */ + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 + -379 -379 -379 -379 +/* AU.UU.. @ */ + -379 -379 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-1288 -1368 -1058 -1038 +/* UA.GA..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 -1198 + -1318 -1618 -1828 -1618 + -1188 -1488 -1698 -1488 +/* UA.GC..CG */ + -1328 -1628 -1838 -1628 + -828 -1128 -1338 -1128 + -1318 -1618 -1828 -1618 + -1118 -1418 -1628 -1418 +/* UA.GG..CG */ + -1408 -1708 -1918 -1708 + -898 -1198 -1408 -1198 + -1318 -1618 -1828 -1618 + -1188 -1488 -1698 -1488 +/* UA.GU..CG */ + -1408 -1708 -1918 -1708 + -1048 -1348 -1558 -1348 + -1318 -1618 -1828 -1618 + -1238 -1538 -1748 -1538 +/* UA.UA..CG */ + -1308 -1168 -1308 -1169 + -798 -658 -798 -659 + -1218 -1078 -1218 -1079 + -1088 -948 -1088 -949 +/* UA.UC..CG */ + -1228 -1088 -1228 -1089 + -728 -588 -728 -589 + -1218 -1078 -1218 -1079 + -1018 -878 -1018 -879 +/* UA.UG..CG */ + -1308 -1168 -1308 -1169 + -798 -658 -798 -659 + -1218 -1078 -1218 -1079 + -1088 -948 -1088 -949 +/* UA.UU..CG */ + -1308 -1168 -1308 -1169 + -948 -808 -948 -809 + -1218 -1078 -1218 -1079 + -1138 -998 -1138 -999 +/* UA.AA..GC */ + -918 -1148 -1408 -1108 + -1118 -1348 -1608 -1308 + -1108 -1338 -1598 -1298 + -898 -1128 -1388 -1088 +/* UA.AC..GC */ + -1278 -1508 -1768 -1468 + -708 -938 -1198 -898 + -1138 -1368 -1628 -1328 + -898 -1128 -1388 -1088 +/* UA.AG..GC */ + -958 -1188 -1448 -1148 + -708 -938 -1198 -898 + -1018 -1248 -1508 -1208 + -898 -1128 -1388 -1088 +/* UA.AU..GC */ + -1278 -1508 -1768 -1468 + -788 -1018 -1278 -978 + -1138 -1368 -1628 -1328 + -968 -1198 -1458 -1158 +/* UA.CA..GC */ + -948 -1028 -718 -698 + -1148 -1228 -918 -898 + -1138 -1218 -908 -888 + -928 -1008 -698 -678 +/* UA.CC..GC */ + -1308 -1388 -1078 -1058 + -738 -818 -508 -488 + -1168 -1248 -938 -918 + -928 -1008 -698 -678 +/* UA.CG..GC */ + -988 -1068 -758 -738 + -738 -818 -508 -488 + -1048 -1128 -818 -798 + -928 -1008 -698 -678 +/* UA.CU..GC */ + -1308 -1388 -1078 -1058 + -818 -898 -588 -568 + -1168 -1248 -938 -918 + -998 -1078 -768 -748 +/* UA.GA..GC */ + -898 -1198 -1408 -1198 + -1098 -1398 -1608 -1398 + -1088 -1388 -1598 -1388 + -878 -1178 -1388 -1178 +/* UA.GC..GC */ + -1258 -1558 -1768 -1558 + -688 -988 -1198 -988 + -1118 -1418 -1628 -1418 + -878 -1178 -1388 -1178 +/* UA.GG..GC */ + -938 -1238 -1448 -1238 + -688 -988 -1198 -988 + -998 -1298 -1508 -1298 + -878 -1178 -1388 -1178 +/* UA.GU..GC */ + -1258 -1558 -1768 -1558 + -768 -1068 -1278 -1068 + -1118 -1418 -1628 -1418 + -948 -1248 -1458 -1248 +/* UA.UA..GC */ + -798 -658 -798 -659 + -998 -858 -998 -859 + -988 -848 -988 -849 + -778 -638 -778 -639 +/* UA.UC..GC */ + -1158 -1018 -1158 -1019 + -588 -448 -588 -449 + -1018 -878 -1018 -879 + -778 -638 -778 -639 +/* UA.UG..GC */ + -838 -698 -838 -699 + -588 -448 -588 -449 + -898 -758 -898 -759 + -778 -638 -778 -639 +/* UA.UU..GC */ + -1158 -1018 -1158 -1019 + -668 -528 -668 -529 + -1018 -878 -1018 -879 + -848 -708 -848 -709 +/* UA.AA..GU */ + -828 -1058 -1318 -1018 + -658 -888 -1148 -848 + -738 -968 -1228 -928 + -728 -958 -1218 -918 +/* UA.AC..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AG..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AU..GU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.CA..GU */ + -858 -938 -628 -608 + -688 -768 -458 -438 + -768 -848 -538 -518 + -758 -838 -528 -508 +/* UA.CC..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CG..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CU..GU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.GA..GU */ + -808 -1108 -1318 -1108 + -638 -938 -1148 -938 + -718 -1018 -1228 -1018 + -708 -1008 -1218 -1008 +/* UA.GC..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GG..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GU..GU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.UA..GU */ + -708 -568 -708 -569 + -538 -398 -538 -399 + -618 -478 -618 -479 + -608 -468 -608 -469 +/* UA.UC..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UG..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UU..GU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.AA..UG */ + -1118 -1348 -1608 -1308 + -878 -1108 -1368 -1068 + -1058 -1288 -1548 -1248 + -948 -1178 -1438 -1138 +/* UA.AC..UG */ + -1188 -1418 -1678 -1378 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -838 -1068 -1328 -1028 +/* UA.AG..UG */ + -1358 -1588 -1848 -1548 + -758 -988 -1248 -948 + -1318 -1548 -1808 -1508 + -948 -1178 -1438 -1138 +/* UA.AU..UG */ + -1208 -1438 -1698 -1398 + -878 -1108 -1368 -1068 + -1208 -1438 -1698 -1398 + -758 -988 -1248 -948 +/* UA.CA..UG */ + -1148 -1228 -918 -898 + -908 -988 -678 -658 + -1088 -1168 -858 -838 + -978 -1058 -748 -728 +/* UA.CC..UG */ + -1218 -1298 -988 -968 + -908 -988 -678 -658 + -1238 -1318 -1008 -988 + -868 -948 -638 -618 +/* UA.CG..UG */ + -1388 -1468 -1158 -1138 + -788 -868 -558 -538 + -1348 -1428 -1118 -1098 + -978 -1058 -748 -728 +/* UA.CU..UG */ + -1238 -1318 -1008 -988 + -908 -988 -678 -658 + -1238 -1318 -1008 -988 + -788 -868 -558 -538 +/* UA.GA..UG */ + -1098 -1398 -1608 -1398 + -858 -1158 -1368 -1158 + -1038 -1338 -1548 -1338 + -928 -1228 -1438 -1228 +/* UA.GC..UG */ + -1168 -1468 -1678 -1468 + -858 -1158 -1368 -1158 + -1188 -1488 -1698 -1488 + -818 -1118 -1328 -1118 +/* UA.GG..UG */ + -1338 -1638 -1848 -1638 + -738 -1038 -1248 -1038 + -1298 -1598 -1808 -1598 + -928 -1228 -1438 -1228 +/* UA.GU..UG */ + -1188 -1488 -1698 -1488 + -858 -1158 -1368 -1158 + -1188 -1488 -1698 -1488 + -738 -1038 -1248 -1038 +/* UA.UA..UG */ + -998 -858 -998 -859 + -758 -618 -758 -619 + -938 -798 -938 -799 + -828 -688 -828 -689 +/* UA.UC..UG */ + -1068 -928 -1068 -929 + -758 -618 -758 -619 + -1088 -948 -1088 -949 + -718 -578 -718 -579 +/* UA.UG..UG */ + -1238 -1098 -1238 -1099 + -638 -498 -638 -499 + -1198 -1058 -1198 -1059 + -828 -688 -828 -689 +/* UA.UU..UG */ + -1088 -948 -1088 -949 + -758 -618 -758 -619 + -1088 -948 -1088 -949 + -638 -498 -638 -499 +/* UA.AA..AU */ + -828 -1058 -1318 -1018 + -658 -888 -1148 -848 + -738 -968 -1228 -928 + -728 -958 -1218 -918 +/* UA.AC..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AG..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.AU..AU */ + -998 -1228 -1488 -1188 + -638 -868 -1128 -828 + -1088 -1318 -1578 -1278 + -728 -958 -1218 -918 +/* UA.CA..AU */ + -858 -938 -628 -608 + -688 -768 -458 -438 + -768 -848 -538 -518 + -758 -838 -528 -508 +/* UA.CC..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CG..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.CU..AU */ + -1028 -1108 -798 -778 + -668 -748 -438 -418 + -1118 -1198 -888 -868 + -758 -838 -528 -508 +/* UA.GA..AU */ + -808 -1108 -1318 -1108 + -638 -938 -1148 -938 + -718 -1018 -1228 -1018 + -708 -1008 -1218 -1008 +/* UA.GC..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GG..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.GU..AU */ + -978 -1278 -1488 -1278 + -618 -918 -1128 -918 + -1068 -1368 -1578 -1368 + -708 -1008 -1218 -1008 +/* UA.UA..AU */ + -708 -568 -708 -569 + -538 -398 -538 -399 + -618 -478 -618 -479 + -608 -468 -608 -469 +/* UA.UC..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UG..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.UU..AU */ + -878 -738 -878 -739 + -518 -378 -518 -379 + -968 -828 -968 -829 + -608 -468 -608 -469 +/* UA.AA..UA */ + -798 -1028 -1288 -988 + -828 -1058 -1318 -1018 + -778 -1008 -1268 -968 + -678 -908 -1168 -868 +/* UA.AC..UA */ + -1028 -1258 -1518 -1218 + -908 -1138 -1398 -1098 + -1078 -1308 -1568 -1268 + -538 -768 -1028 -728 +/* UA.AG..UA */ + -1288 -1518 -1778 -1478 + -598 -828 -1088 -788 + -1288 -1518 -1778 -1478 + -678 -908 -1168 -868 +/* UA.AU..UA */ + -988 -1218 -1478 -1178 + -578 -808 -1068 -768 + -1078 -1308 -1568 -1268 + -539 -769 -1029 -729 +/* UA.CA..UA */ + -828 -908 -598 -578 + -858 -938 -628 -608 + -808 -888 -578 -558 + -708 -788 -478 -458 +/* UA.CC..UA */ + -1058 -1138 -828 -808 + -938 -1018 -708 -688 + -1108 -1188 -878 -858 + -568 -648 -338 -318 +/* UA.CG..UA */ + -1318 -1398 -1088 -1068 + -628 -708 -398 -378 + -1318 -1398 -1088 -1068 + -708 -788 -478 -458 +/* UA.CU..UA */ + -1018 -1098 -788 -768 + -608 -688 -378 -358 + -1108 -1188 -878 -858 + -569 -649 -339 -319 +/* UA.GA..UA */ + -778 -1078 -1288 -1078 + -808 -1108 -1318 -1108 + -758 -1058 -1268 -1058 + -658 -958 -1168 -958 +/* UA.GC..UA */ + -1008 -1308 -1518 -1308 + -888 -1188 -1398 -1188 + -1058 -1358 -1568 -1358 + -518 -818 -1028 -818 +/* UA.GG..UA */ + -1268 -1568 -1778 -1568 + -578 -878 -1088 -878 + -1268 -1568 -1778 -1568 + -658 -958 -1168 -958 +/* UA.GU..UA */ + -968 -1268 -1478 -1268 + -558 -858 -1068 -858 + -1058 -1358 -1568 -1358 + -519 -819 -1029 -819 +/* UA.UA..UA */ + -678 -538 -678 -539 + -708 -568 -708 -569 + -658 -518 -658 -519 + -558 -418 -558 -419 +/* UA.UC..UA */ + -908 -768 -908 -769 + -788 -648 -788 -649 + -958 -818 -958 -819 + -418 -278 -418 -279 +/* UA.UG..UA */ + -1168 -1028 -1168 -1029 + -478 -338 -478 -339 + -1168 -1028 -1168 -1029 + -558 -418 -558 -419 +/* UA.UU..UA */ + -868 -728 -868 -729 + -458 -318 -458 -319 + -958 -818 -958 -819 + -419 -279 -419 -280 +/* UA.AA.. @ */ + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 +/* UA.AC.. @ */ + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 +/* UA.AG.. @ */ + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 +/* UA.AU.. @ */ + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 + -449 -679 -939 -639 +/* UA.CA.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CC.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CG.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.CU.. @ */ + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 + -479 -559 -249 -229 +/* UA.GA.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GC.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GG.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.GU.. @ */ + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 + -429 -729 -939 -729 +/* UA.UA.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UC.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UG.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* UA.UU.. @ */ + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 + -329 -189 -329 -190 +/* @.AA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.AC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.AG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.AU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.CA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.CC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.CG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.CU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.GA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.GC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.GG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.GU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.UA..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.UC..CG */ + -999 -999 -999 -999 + -499 -499 -499 -499 + -989 -989 -989 -989 + -789 -789 -789 -789 +/* @.UG..CG */ + -1079 -1079 -1079 -1079 + -569 -569 -569 -569 + -989 -989 -989 -989 + -859 -859 -859 -859 +/* @.UU..CG */ + -1079 -1079 -1079 -1079 + -719 -719 -719 -719 + -989 -989 -989 -989 + -909 -909 -909 -909 +/* @.AA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.AC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.AG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.AU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.CA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.CC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.CG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.CU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.GA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.GC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.GG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.GU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.UA..GC */ + -569 -569 -569 -569 + -769 -769 -769 -769 + -759 -759 -759 -759 + -549 -549 -549 -549 +/* @.UC..GC */ + -929 -929 -929 -929 + -359 -359 -359 -359 + -789 -789 -789 -789 + -549 -549 -549 -549 +/* @.UG..GC */ + -609 -609 -609 -609 + -359 -359 -359 -359 + -669 -669 -669 -669 + -549 -549 -549 -549 +/* @.UU..GC */ + -929 -929 -929 -929 + -439 -439 -439 -439 + -789 -789 -789 -789 + -619 -619 -619 -619 +/* @.AA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.AC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.CC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.GC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UA..GU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.UC..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UG..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UU..GU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.AC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.AG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.AU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.CA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.CC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.CG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.CU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.GA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.GC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.GG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.GU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.UA..UG */ + -769 -769 -769 -769 + -529 -529 -529 -529 + -709 -709 -709 -709 + -599 -599 -599 -599 +/* @.UC..UG */ + -839 -839 -839 -839 + -529 -529 -529 -529 + -859 -859 -859 -859 + -489 -489 -489 -489 +/* @.UG..UG */ + -1009 -1009 -1009 -1009 + -409 -409 -409 -409 + -969 -969 -969 -969 + -599 -599 -599 -599 +/* @.UU..UG */ + -859 -859 -859 -859 + -529 -529 -529 -529 + -859 -859 -859 -859 + -409 -409 -409 -409 +/* @.AA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.AC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.CC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.CU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.GC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.GU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UA..AU */ + -479 -479 -479 -479 + -309 -309 -309 -309 + -389 -389 -389 -389 + -379 -379 -379 -379 +/* @.UC..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UG..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.UU..AU */ + -649 -649 -649 -649 + -289 -289 -289 -289 + -739 -739 -739 -739 + -379 -379 -379 -379 +/* @.AA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.AC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.AG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.AU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.CA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.CC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.CG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.CU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.GA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.GC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.GG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.GU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.UA..UA */ + -449 -449 -449 -449 + -479 -479 -479 -479 + -429 -429 -429 -429 + -329 -329 -329 -329 +/* @.UC..UA */ + -679 -679 -679 -679 + -559 -559 -559 -559 + -729 -729 -729 -729 + -189 -189 -189 -189 +/* @.UG..UA */ + -939 -939 -939 -939 + -249 -249 -249 -249 + -939 -939 -939 -939 + -329 -329 -329 -329 +/* @.UU..UA */ + -639 -639 -639 -639 + -229 -229 -229 -229 + -729 -729 -729 -729 + -190 -190 -190 -190 +/* @.AA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.AU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.CU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.GU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UA.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UC.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UG.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 +/* @.UU.. @ */ + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + -100 -100 -100 -100 + +# hairpin + INF INF INF 410 490 440 470 500 510 520 + 531 542 551 560 568 575 582 589 595 601 + 606 611 616 621 626 630 634 638 642 646 + 650 + +# bulge + INF 390 310 350 420 480 500 516 531 543 + 555 565 574 583 591 598 605 612 618 624 + 630 635 640 645 649 654 658 662 666 670 + 673 + +# internal_loop + INF INF 410 510 490 530 570 587 601 614 + 625 635 645 653 661 669 676 682 688 694 + 700 705 710 715 720 724 728 732 736 740 + 744 + +# ML_params +/* F = cu*n_unpaired + cc + ci*loop_degree (+TermAU) */ +/* cu cc ci TerminalAU */ + 40 460 10 0 + +# NINIO +/* Ninio = MIN(max, m*|n1-n2| */ +/* m max */ + 30 300 + +# Tetraloops + GGAAAC -200 + GGCAAC -200 + GGAGAC -200 + GGUGAC -200 + GGGAAC -200 + GUUCGC -200 + GUACGC -200 + GGCGAC -200 + GUCCGC -200 + GGUAAC -200 + GCUUGC -200 + GAUUUC -200 + GUUUAC -200 + CGAAAG -200 + CGCAAG -200 + CGAGAG -200 + CGUGAG -200 + CGGAAG -200 + CUUCGG -200 + CUACGG -200 + CGCGAG -200 + CUCCGG -200 + CGUAAG -200 + CCUUGG -200 + CAUUUG -200 + CUUUAG -200 + GGAAAU -200 + GGCAAU -200 + GGAGAU -200 + GGUGAU -200 + GGGAAU -200 + GUUCGU -200 + GUACGU -200 + GGCGAU -200 + GUCCGU -200 + GGUAAU -200 + GCUUGU -200 + GAUUUU -200 + GUUUAU -200 + UGAAAG -200 + UGCAAG -200 + UGAGAG -200 + UGUGAG -200 + UGGAAG -200 + UUUCGG -200 + UUACGG -200 + UGCGAG -200 + UUCCGG -200 + UGUAAG -200 + UCUUGG -200 + UAUUUG -200 + UUUUAG -200 + AGAAAU -200 + AGCAAU -200 + AGAGAU -200 + AGUGAU -200 + AGGAAU -200 + AUUCGU -200 + AUACGU -200 + AGCGAU -200 + AUCCGU -200 + AGUAAU -200 + ACUUGU -200 + AAUUUU -200 + AUUUAU -200 + UGAAAA -200 + UGCAAA -200 + UGAGAA -200 + UGUGAA -200 + UGGAAA -200 + UUUCGA -200 + UUACGA -200 + UGCGAA -200 + UUCCGA -200 + UGUAAA -200 + UCUUGA -200 + UAUUUA -200 + UUUUAA -200 + +# Triloops + +#END diff --git a/modules/local/pita/templates/known_mirs/fly_mirs.fasta b/modules/local/pita/templates/known_mirs/fly_mirs.fasta new file mode 100644 index 00000000..86a9b0a3 --- /dev/null +++ b/modules/local/pita/templates/known_mirs/fly_mirs.fasta @@ -0,0 +1,294 @@ +>dme-miR-1 +UGGAAUGUAAAGAAGUAUGGAG +>dme-miR-2a +UAUCACAGCCAGCUUUGAUGAGC +>dme-miR-2b +UAUCACAGCCAGCUUUGAGGAGC +>dme-miR-3 +UCACUGGGCAAAGUGUGUCUCA +>dme-miR-4 +AUAAAGCUAGACAACCAUUGA +>dme-miR-5 +AAAGGAACGAUCGUUGUGAUAUG +>dme-miR-6 +UAUCACAGUGGCUGUUCUUUUU +>dme-miR-7 +UGGAAGACUAGUGAUUUUGUUGU +>dme-miR-8 +UAAUACUGUCAGGUAAAGAUGUC +>dme-miR-9a +UCUUUGGUUAUCUAGCUGUAUGA +>dme-miR-10 +ACCCUGUAGAUCCGAAUUUGU +>dme-miR-11 +CAUCACAGUCUGAGUUCUUGC +>dme-miR-12 +UGAGUAUUACAUCAGGUACUGGU +>dme-miR-13a +UAUCACAGCCAUUUUGAUGAGU +>dme-miR-13b +UAUCACAGCCAUUUUGACGAGU +>dme-miR-14 +UCAGUCUUUUUCUCUCUCCUA +>dme-miR-263a +GUUAAUGGCACUGGAAGAAUUCAC +>dme-miR-184 +UGGACGGAGAACUGAUAAGGGC +>dme-miR-274 +UUUUGUGACCGACACUAACGGGUAAU +>dme-miR-275 +UCAGGUACCUGAAGUAGCGCGCG +>dme-miR-92a +CAUUGCACUUGUCCCGGCCUAU +>dme-miR-219 +UGAUUGUCCAAACGCAAUUCUUG +>dme-miR-276a +UAGGAACUUCAUACCGUGCUCU +>dme-miR-277 +UAAAUGCACUAUCUGGUACGACA +>dme-miR-278 +UCGGUGGGACUUUCGUCCGUUU +>dme-miR-133 +UUGGUCCCCUUCAACCAGCUGU +>dme-miR-279 +UGACUAGAUCCACACUCAUUAA +>dme-miR-33 +AGGUGCAUUGUAGUCGCAUUG +>dme-miR-280 +UGUAUUUACGUUGCAUAUGAAAUGAUA +>dme-miR-281 +UGUCAUGGAAUUGCUCUCUUUGU +>dme-miR-282 +AAUCUAGCCUCUACUAGGCUUUGUCUGU +>dme-miR-283 +UAAAUAUCAGCUGGUAAUUCU +>dme-miR-284 +UGAAGUCAGCAACUUGAUUCCAGCAAUUG +>dme-miR-34 +UGGCAGUGUGGUUAGCUGGUUGUG +>dme-miR-124 +UAAGGCACGCGGUGAAUGCCAAG +>dme-miR-79 +UAAAGCUAGAUUACCAAAGCAU +>dme-miR-276b +UAGGAACUUAAUACCGUGCUCU +>dme-miR-210 +UUGUGCGUGUGACAGCGGCUA +>dme-miR-285 +UAGCACCAUUCGAAAUCAGUGC +>dme-miR-100 +AACCCGUAAAUCCGAACUUGUG +>dme-miR-92b +AAUUGCACUAGUCCCGGCCUGC +>dme-miR-286 +UGACUAGACCGAACACUCGUGCU +>dme-miR-287 +UGUGUUGAAAAUCGUUUGCAC +>dme-miR-87 +UUGAGCAAAAUUUCAGGUGUG +>dme-miR-263b +CUUGGCACUGGGAGAAUUCAC +>dme-miR-288 +UUUCAUGUCGAUUUCAUUUCAUG +>dme-miR-289 +UAAAUAUUUAAGUGGAGCCUGCGACU +>dme-bantam +UGAGAUCAUUUUGAAAGCUGAUU +>dme-miR-303 +UUUAGGUUUCACAGGAAACUGGU +>dme-miR-31b +UGGCAAGAUGUCGGAAUAGCUG +>dme-miR-304 +UAAUCUCAAUUUGUAAAUGUGAG +>dme-miR-305 +AUUGUACUUCAUCAGGUGCUCUG +>dme-miR-9c +UCUUUGGUAUUCUAGCUGUAGA +>dme-miR-306 +UCAGGUACUUAGUGACUCUCAA +>dme-miR-9b +UCUUUGGUGAUUUUAGCUGUAUG +>dme-let-7 +UGAGGUAGUAGGUUGUAUAGU +>dme-miR-125 +UCCCUGAGACCCUAACUUGUGA +>dme-miR-307 +UCACAACCUCCUUGAGUGAG +>dme-miR-308 +AAUCACAGGAUUAUACUGUGAG +>dme-miR-31a +UGGCAAGAUGUCGGCAUAGCUGA +>dme-miR-309 +GCACUGGGUAAAGUUUGUCCUA +>dme-miR-310 +UAUUGCACACUUCCCGGCCUUU +>dme-miR-311 +UAUUGCACAUUCACCGGCCUGA +>dme-miR-312 +UAUUGCACUUGAGACGGCCUGA +>dme-miR-313 +UAUUGCACUUUUCACAGCCCGA +>dme-miR-314 +UAUUCGAGCCAAUAAGUUCGG +>dme-miR-315 +UUUUGAUUGUUGCUCAGAAAGC +>dme-miR-316 +UGUCUUUUUCCGCUUACUGGCG +>dme-miR-317 +UGAACACAGCUGGUGGUAUCCAGU +>dme-miR-318 +UCACUGGGCUUUGUUUAUCUCA +>dme-miR-2c +UAUCACAGCCAGCUUUGAUGGGC +>dme-miR-iab-4-5p +ACGUAUACUGAAUGUAUCCUGA +>dme-miR-iab-4-3p +CGGUAUACCUUCAGUAUACGUAAC +>dme-miR-iab-4as-5p +UUACGUAUACUGAAGGUAUACCG +>dme-miR-iab-4as-3p +GGAUACAUUCAGUAUACGUUUA +>dme-miR-954 +UCUGGGUGUUGCGUUGUGUGU +>dme-miR-955 +CAUCGUGCAGAGGUUUGAGUGUC +>dme-miR-190 +AGAUAUGUUUGAUAUUCUUGGUUG +>dme-miR-193 +UACUGGCCUACUAAGUCCCAAC +>dme-miR-956 +UUUCGAGACCACUCUAAUCCAUU +>dme-miR-957 +UGAAACCGUCCAAAACUGAGGC +>dme-miR-958 +UGAGAUUCUUCUAUUCUACUUU +>dme-miR-375 +UUUGUUCGUUUGGCUUAAGUUA +>dme-miR-959 +UUGUCAUCGGGGGUAUUAUGAA +>dme-miR-960 +UGAGUAUUCCAGAUUGCAUAGC +>dme-miR-961 +UUUGAUCACCAGUAACUGAGAU +>dme-miR-962 +AUAAGGUAGAGAAAUUGAUGCUGUC +>dme-miR-963 +ACAAGGUAAAUAUCAGGUUGUUUC +>dme-miR-964 +UUAGAAUAGGGGAGCUUAACUU +>dme-miR-932 +UCAAUUCCGUAGUGCAUUGCAG +>dme-miR-965 +UAAGCGUAUAGCUUUUCCCCUU +>dme-miR-966 +UGUGGGUUGUGGGCUGUGUGG +>dme-miR-967 +AGAGAUACCUCUGGAGAAGCG +>dme-miR-1002 +UUAAGUAGUGGAUACAAAGGGCGA +>dme-miR-968 +UAAGUAGUAUCCAUUAAAGGGUUG +>dme-miR-969 +GAGUUCCACUAAGCAAGUUUU +>dme-miR-970 +UCAUAAGACACACGCGGCUAU +>dme-miR-971 +UUGGUGUUACUUCUUACAGUGA +>dme-miR-972 +UGUACAAUACGAAUAUUUAGGC +>dme-miR-973 +UGGUUGGUGGUUGAACUUCGAUUUU +>dme-miR-974 +AAGCGAGCAAAGAAGUAGUAUU +>dme-miR-975 +UAAACACUUCCUACAUCCUGUAU +>dme-miR-976 +UUGGAUUAGUUAUCAUCAAUGC +>dme-miR-977 +UGAGAUAUUCACGUUGUCUAA +>dme-miR-978 +UGUCCAGUGCCGUAAAUUGCAG +>dme-miR-979 +UUCUUCCCGAACUCAGGCUAA +>dme-miR-980 +UAGCUGCCUUGUGAAGGGCUUA +>dme-miR-981 +UUCGUUGUCGACGAAACCUGCA +>dme-miR-982 +UCCUGGACAAAUAUGAAGUAAAU +>dme-miR-983 +AUAAUACGUUUCGAACUAAUGA +>dme-miR-984 +UGAGGUAAAUACGGUUGGAAUUU +>dme-miR-927 +UUUAGAAUUCCUACGCUUUACC +>dme-miR-985 +CAAAUGUUCCAAUGGUCGGGCA +>dme-miR-986 +UCUCGAAUAGCGUUGUGACUGA +>dme-miR-987 +UAAAGUAAAUAGUCUGGAUUGAUG +>dme-miR-988 +CCCCUUGUUGCAAACCUCACGC +>dme-miR-989 +UGUGAUGUGACGUAGUGGAAC +>dme-miR-137 +UAUUGCUUGAGAAUACACGUAG +>dme-miR-990 +AUUCACCGUUCUGAGUUGGCC +>dme-miR-991 +UUAAAGUUGUAGUUUGGAAAGU +>dme-miR-992 +AGUACACGUUUCUGGUACUAAG +>dme-miR-929 +CUCCCUAACGGAGUCAGAUUG +>dme-miR-993 +GAAGCUCGUCUCUACAGGUAUCU +>dme-miR-994 +CUAAGGAAAUAGUAGCCGUGAU +>dme-miR-995 +UAGCACCACAUGAUUCGGCUU +>dme-miR-996 +UGACUAGAUUUCAUGCUCGUCU +>dme-miR-252 +CUAAGUACUAGUGCCGCAGGAG +>dme-miR-997 +CCCAAACUCGAAGGAGUUUCA +>dme-miR-998 +UAGCACCAUGAGAUUCAGCUC +>dme-miR-999 +UGUUAACUGUAAGACUGUGUCU +>dme-miR-1000 +AUAUUGUCCUGUCACAGCAGU +>dme-miR-1001 +UGGGUAAACUCCCAAGGAUCA +>dme-miR-1003 +UCUCACAUUUACAUAUUCACAG +>dme-miR-1004 +UCUCACAUCACUUCCCUCACAG +>dme-miR-1005 +UCUGGAAUCUUUAAUUCGCAG +>dme-miR-1006 +UAAAUUCGAUUUCUUAUUCAUAG +>dme-miR-1007 +UAAGCUCAAUUAACUGUUUGCA +>dme-miR-1008 +UCACAGCUUUUUGUGUUUACA +>dme-miR-1009 +UCUCAAAAAUUGUUACAUUUCAG +>dme-miR-1010 +UUUCACCUAUCGUUCCAUUUGCAG +>dme-miR-1011 +UUAUUGGUUCAAAUCGCUCGCAG +>dme-miR-1012 +UUAGUCAAAGAUUUUCCCCAUAG +>dme-miR-1013 +AUAAAAGUAUGCCGAACUCG +>dme-miR-1014 +AAAAUUCAUUUUCAUUUGCAG +>dme-miR-1015 +UCCUGGGACAUCUCUCUUGCAG +>dme-miR-1016 +UUCACCUCUCUCCAUACUUAG +>dme-miR-1017 +GAAAGCUCUACCCAAACUCAUCC diff --git a/modules/local/pita/templates/known_mirs/human_mirs.fasta b/modules/local/pita/templates/known_mirs/human_mirs.fasta new file mode 100644 index 00000000..5accdc5f --- /dev/null +++ b/modules/local/pita/templates/known_mirs/human_mirs.fasta @@ -0,0 +1,1354 @@ +>hsa-let-7a +UGAGGUAGUAGGUUGUAUAGUU +>hsa-let-7b +UGAGGUAGUAGGUUGUGUGGUU +>hsa-let-7c +UGAGGUAGUAGGUUGUAUGGUU +>hsa-let-7d +AGAGGUAGUAGGUUGCAUAGUU +>hsa-let-7e +UGAGGUAGGAGGUUGUAUAGUU +>hsa-let-7f +UGAGGUAGUAGAUUGUAUAGUU +>hsa-miR-15a +UAGCAGCACAUAAUGGUUUGUG +>hsa-miR-16 +UAGCAGCACGUAAAUAUUGGCG +>hsa-miR-17 +CAAAGUGCUUACAGUGCAGGUAG +>hsa-miR-18a +UAAGGUGCAUCUAGUGCAGAUAG +>hsa-miR-19a +UGUGCAAAUCUAUGCAAAACUGA +>hsa-miR-19b +UGUGCAAAUCCAUGCAAAACUGA +>hsa-miR-20a +UAAAGUGCUUAUAGUGCAGGUAG +>hsa-miR-21 +UAGCUUAUCAGACUGAUGUUGA +>hsa-miR-22 +AAGCUGCCAGUUGAAGAACUGU +>hsa-miR-23a +AUCACAUUGCCAGGGAUUUCC +>hsa-miR-24 +UGGCUCAGUUCAGCAGGAACAG +>hsa-miR-25 +CAUUGCACUUGUCUCGGUCUGA +>hsa-miR-26a +UUCAAGUAAUCCAGGAUAGGCU +>hsa-miR-26b +UUCAAGUAAUUCAGGAUAGGU +>hsa-miR-27a +UUCACAGUGGCUAAGUUCCGC +>hsa-miR-28-5p +AAGGAGCUCACAGUCUAUUGAG +>hsa-miR-28-3p +CACUAGAUUGUGAGCUCCUGGA +>hsa-miR-29a +UAGCACCAUCUGAAAUCGGUUA +>hsa-miR-30a +UGUAAACAUCCUCGACUGGAAG +>hsa-miR-31 +AGGCAAGAUGCUGGCAUAGCU +>hsa-miR-32 +UAUUGCACAUUACUAAGUUGCA +>hsa-miR-33a +GUGCAUUGUAGUUGCAUUGCA +>hsa-miR-92a +UAUUGCACUUGUCCCGGCCUGU +>hsa-miR-93 +CAAAGUGCUGUUCGUGCAGGUAG +>hsa-miR-95 +UUCAACGGGUAUUUAUUGAGCA +>hsa-miR-96 +UUUGGCACUAGCACAUUUUUGCU +>hsa-miR-98 +UGAGGUAGUAAGUUGUAUUGUU +>hsa-miR-99a +AACCCGUAGAUCCGAUCUUGUG +>hsa-miR-100 +AACCCGUAGAUCCGAACUUGUG +>hsa-miR-101 +UACAGUACUGUGAUAACUGAA +>hsa-miR-29b +UAGCACCAUUUGAAAUCAGUGUU +>hsa-miR-103 +AGCAGCAUUGUACAGGGCUAUGA +>hsa-miR-105 +UCAAAUGCUCAGACUCCUGUGGU +>hsa-miR-106a +AAAAGUGCUUACAGUGCAGGUAG +>hsa-miR-107 +AGCAGCAUUGUACAGGGCUAUCA +>hsa-miR-192 +CUGACCUAUGAAUUGACAGCC +>hsa-miR-196a +UAGGUAGUUUCAUGUUGUUGGG +>hsa-miR-197 +UUCACCACCUUCUCCACCCAGC +>hsa-miR-198 +GGUCCAGAGGGGAGAUAGGUUC +>hsa-miR-199a-5p +CCCAGUGUUCAGACUACCUGUUC +>hsa-miR-199a-3p +ACAGUAGUCUGCACAUUGGUUA +>hsa-miR-208a +AUAAGACGAGCAAAAAGCUUGU +>hsa-miR-129-5p +CUUUUUGCGGUCUGGGCUUGC +>hsa-miR-148a +UCAGUGCACUACAGAACUUUGU +>hsa-miR-30c +UGUAAACAUCCUACACUCUCAGC +>hsa-miR-30d +UGUAAACAUCCCCGACUGGAAG +>hsa-miR-139-5p +UCUACAGUGCACGUGUCUCCAG +>hsa-miR-139-3p +GGAGACGCGGCCCUGUUGGAGU +>hsa-miR-147 +GUGUGUGGAAAUGCUUCUGC +>hsa-miR-7 +UGGAAGACUAGUGAUUUUGUUGU +>hsa-miR-10a +UACCCUGUAGAUCCGAAUUUGUG +>hsa-miR-10b +UACCCUGUAGAACCGAAUUUGUG +>hsa-miR-34a +UGGCAGUGUCUUAGCUGGUUGU +>hsa-miR-181a +AACAUUCAACGCUGUCGGUGAGU +>hsa-miR-181b +AACAUUCAUUGCUGUCGGUGGGU +>hsa-miR-181c +AACAUUCAACCUGUCGGUGAGU +>hsa-miR-182 +UUUGGCAAUGGUAGAACUCACACU +>hsa-miR-183 +UAUGGCACUGGUAGAAUUCACU +>hsa-miR-187 +UCGUGUCUUGUGUUGCAGCCGG +>hsa-miR-199b-5p +CCCAGUGUUUAGACUAUCUGUUC +>hsa-miR-199b-3p +ACAGUAGUCUGCACAUUGGUUA +>hsa-miR-203 +GUGAAAUGUUUAGGACCACUAG +>hsa-miR-204 +UUCCCUUUGUCAUCCUAUGCCU +>hsa-miR-205 +UCCUUCAUUCCACCGGAGUCUG +>hsa-miR-210 +CUGUGCGUGUGACAGCGGCUGA +>hsa-miR-211 +UUCCCUUUGUCAUCCUUCGCCU +>hsa-miR-212 +UAACAGUCUCCAGUCACGGCC +>hsa-miR-214 +ACAGCAGGCACAGACAGGCAGU +>hsa-miR-215 +AUGACCUAUGAAUUGACAGAC +>hsa-miR-216a +UAAUCUCAGCUGGCAACUGUGA +>hsa-miR-217 +UACUGCAUCAGGAACUGAUUGGA +>hsa-miR-218 +UUGUGCUUGAUCUAACCAUGU +>hsa-miR-219-5p +UGAUUGUCCAAACGCAAUUCU +>hsa-miR-219-1-3p +AGAGUUGAGUCUGGACGUCCCG +>hsa-miR-220a +CCACACCGUAUCUGACACUUU +>hsa-miR-221 +AGCUACAUUGUCUGCUGGGUUUC +>hsa-miR-222 +AGCUACAUCUGGCUACUGGGU +>hsa-miR-223 +UGUCAGUUUGUCAAAUACCCCA +>hsa-miR-224 +CAAGUCACUAGUGGUUCCGUU +>hsa-miR-200b +UAAUACUGCCUGGUAAUGAUGA +>hsa-let-7g +UGAGGUAGUAGUUUGUACAGUU +>hsa-let-7i +UGAGGUAGUAGUUUGUGCUGUU +>hsa-miR-1 +UGGAAUGUAAAGAAGUAUGUAU +>hsa-miR-15b +UAGCAGCACAUCAUGGUUUACA +>hsa-miR-23b +AUCACAUUGCCAGGGAUUACC +>hsa-miR-27b +UUCACAGUGGCUAAGUUCUGC +>hsa-miR-30b +UGUAAACAUCCUACACUCAGCU +>hsa-miR-122 +UGGAGUGUGACAAUGGUGUUUG +>hsa-miR-124 +UAAGGCACGCGGUGAAUGCC +>hsa-miR-125b +UCCCUGAGACCCUAACUUGUGA +>hsa-miR-128 +UCACAGUGAACCGGUCUCUUU +>hsa-miR-130a +CAGUGCAAUGUUAAAAGGGCAU +>hsa-miR-132 +UAACAGUCUACAGCCAUGGUCG +>hsa-miR-133a +UUUGGUCCCCUUCAACCAGCUG +>hsa-miR-135a +UAUGGCUUUUUAUUCCUAUGUGA +>hsa-miR-137 +UUAUUGCUUAAGAAUACGCGUAG +>hsa-miR-138 +AGCUGGUGUUGUGAAUCAGGCCG +>hsa-miR-140-5p +CAGUGGUUUUACCCUAUGGUAG +>hsa-miR-140-3p +UACCACAGGGUAGAACCACGG +>hsa-miR-141 +UAACACUGUCUGGUAAAGAUGG +>hsa-miR-142-5p +CAUAAAGUAGAAAGCACUACU +>hsa-miR-142-3p +UGUAGUGUUUCCUACUUUAUGGA +>hsa-miR-143 +UGAGAUGAAGCACUGUAGCUC +>hsa-miR-144 +UACAGUAUAGAUGAUGUACU +>hsa-miR-145 +GUCCAGUUUUCCCAGGAAUCCCU +>hsa-miR-152 +UCAGUGCAUGACAGAACUUGG +>hsa-miR-153 +UUGCAUAGUCACAAAAGUGAUC +>hsa-miR-191 +CAACGGAAUCCCAAAAGCAGCUG +>hsa-miR-9 +UCUUUGGUUAUCUAGCUGUAUGA +>hsa-miR-125a-5p +UCCCUGAGACCCUUUAACCUGUGA +>hsa-miR-125a-3p +ACAGGUGAGGUUCUUGGGAGCC +>hsa-miR-126 +UCGUACCGUGAGUAAUAAUGCG +>hsa-miR-127-5p +CUGAAGCUCAGAGGGCUCUGAU +>hsa-miR-127-3p +UCGGAUCCGUCUGAGCUUGGCU +>hsa-miR-129-3p +AAGCCCUUACCCCAAAAAGCAU +>hsa-miR-134 +UGUGACUGGUUGACCAGAGGGG +>hsa-miR-136 +ACUCCAUUUGUUUUGAUGAUGGA +>hsa-miR-146a +UGAGAACUGAAUUCCAUGGGUU +>hsa-miR-149 +UCUGGCUCCGUGUCUUCACUCCC +>hsa-miR-150 +UCUCCCAACCCUUGUACCAGUG +>hsa-miR-154 +UAGGUUAUCCGUGUUGCCUUCG +>hsa-miR-184 +UGGACGGAGAACUGAUAAGGGU +>hsa-miR-185 +UGGAGAGAAAGGCAGUUCCUGA +>hsa-miR-186 +CAAAGAAUUCUCCUUUUGGGCU +>hsa-miR-188-5p +CAUCCCUUGCAUGGUGGAGGG +>hsa-miR-188-3p +CUCCCACAUGCAGGGUUUGCA +>hsa-miR-190 +UGAUAUGUUUGAUAUAUUAGGU +>hsa-miR-193a-5p +UGGGUCUUUGCGGGCGAGAUGA +>hsa-miR-193a-3p +AACUGGCCUACAAAGUCCCAGU +>hsa-miR-194 +UGUAACAGCAACUCCAUGUGGA +>hsa-miR-195 +UAGCAGCACAGAAAUAUUGGC +>hsa-miR-206 +UGGAAUGUAAGGAAGUGUGUGG +>hsa-miR-320a +AAAAGCUGGGUUGAGAGGGCGA +>hsa-miR-200c +UAAUACUGCCGGGUAAUGAUGGA +>hsa-miR-155 +UUAAUGCUAAUCGUGAUAGGGGU +>hsa-miR-106b +UAAAGUGCUGACAGUGCAGAU +>hsa-miR-29c +UAGCACCAUUUGAAAUCGGUUA +>hsa-miR-200a +UAACACUGUCUGGUAACGAUGU +>hsa-miR-302a +UAAGUGCUUCCAUGUUUUGGUGA +>hsa-miR-219-2-3p +AGAAUUGUGGCUGGACAUCUGU +>hsa-miR-34b +CAAUCACUAACUCCACUGCCAU +>hsa-miR-34c-5p +AGGCAGUGUAGUUAGCUGAUUGC +>hsa-miR-34c-3p +AAUCACUAACCACACGGCCAGG +>hsa-miR-299-5p +UGGUUUACCGUCCCACAUACAU +>hsa-miR-299-3p +UAUGUGGGAUGGUAAACCGCUU +>hsa-miR-301a +CAGUGCAAUAGUAUUGUCAAAGC +>hsa-miR-99b +CACCCGUAGAACCGACCUUGCG +>hsa-miR-296-5p +AGGGCCCCCCCUCAAUCCUGU +>hsa-miR-296-3p +GAGGGUUGGGUGGAGGCUCUCC +>hsa-miR-130b +CAGUGCAAUGAUGAAAGGGCAU +>hsa-miR-30e +UGUAAACAUCCUUGACUGGAAG +>hsa-miR-361-5p +UUAUCAGAAUCUCCAGGGGUAC +>hsa-miR-361-3p +UCCCCCAGGUGUGAUUCUGAUUU +>hsa-miR-362-5p +AAUCCUUGGAACCUAGGUGUGAGU +>hsa-miR-362-3p +AACACACCUAUUCAAGGAUUCA +>hsa-miR-363 +AAUUGCACGGUAUCCAUCUGUA +>hsa-miR-365 +UAAUGCCCCUAAAAAUCCUUAU +>hsa-miR-302b +UAAGUGCUUCCAUGUUUUAGUAG +>hsa-miR-302c +UAAGUGCUUCCAUGUUUCAGUGG +>hsa-miR-302d +UAAGUGCUUCCAUGUUUGAGUGU +>hsa-miR-367 +AAUUGCACUUUAGCAAUGGUGA +>hsa-miR-376c +AACAUAGAGGAAAUUCCACGU +>hsa-miR-369-5p +AGAUCGACCGUGUUAUAUUCGC +>hsa-miR-369-3p +AAUAAUACAUGGUUGAUCUUU +>hsa-miR-370 +GCCUGCUGGGGUGGAACCUGGU +>hsa-miR-371-5p +ACUCAAACUGUGGGGGCACU +>hsa-miR-371-3p +AAGUGCCGCCAUCUUUUGAGUGU +>hsa-miR-372 +AAAGUGCUGCGACAUUUGAGCGU +>hsa-miR-373 +GAAGUGCUUCGAUUUUGGGGUGU +>hsa-miR-374a +UUAUAAUACAACCUGAUAAGUG +>hsa-miR-375 +UUUGUUCGUUCGGCUCGCGUGA +>hsa-miR-376a +AUCAUAGAGGAAAAUCCACGU +>hsa-miR-377 +AUCACACAAAGGCAACUUUUGU +>hsa-miR-378 +ACUGGACUUGGAGUCAGAAGG +>hsa-miR-379 +UGGUAGACUAUGGAACGUAGG +>hsa-miR-380 +UAUGUAAUAUGGUCCACAUCUU +>hsa-miR-381 +UAUACAAGGGCAAGCUCUCUGU +>hsa-miR-382 +GAAGUUGUUCGUGGUGGAUUCG +>hsa-miR-383 +AGAUCAGAAGGUGAUUGUGGCU +>hsa-miR-340 +UUAUAAAGCAAUGAGACUGAUU +>hsa-miR-330-5p +UCUCUGGGCCUGUGUCUUAGGC +>hsa-miR-330-3p +GCAAAGCACACGGCCUGCAGAGA +>hsa-miR-328 +CUGGCCCUCUCUGCCCUUCCGU +>hsa-miR-342-5p +AGGGGUGCUAUCUGUGAUUGA +>hsa-miR-342-3p +UCUCACACAGAAAUCGCACCCGU +>hsa-miR-337-5p +GAACGGCUUCAUACAGGAGUU +>hsa-miR-337-3p +CUCCUAUAUGAUGCCUUUCUUC +>hsa-miR-323-5p +AGGUGGUCCGUGGCGCGUUCGC +>hsa-miR-323-3p +CACAUUACACGGUCGACCUCU +>hsa-miR-326 +CCUCUGGGCCCUUCCUCCAG +>hsa-miR-151-5p +UCGAGGAGCUCACAGUCUAGU +>hsa-miR-151-3p +CUAGACUGAAGCUCCUUGAGG +>hsa-miR-135b +UAUGGCUUUUCAUUCCUAUGUGA +>hsa-miR-148b +UCAGUGCAUCACAGAACUUUGU +>hsa-miR-331-5p +CUAGGUAUGGUCCCAGGGAUCC +>hsa-miR-331-3p +GCCCCUGGGCCUAUCCUAGAA +>hsa-miR-324-5p +CGCAUCCCCUAGGGCAUUGGUGU +>hsa-miR-324-3p +ACUGCCCCAGGUGCUGCUGG +>hsa-miR-338-5p +AACAAUAUCCUGGUGCUGAGUG +>hsa-miR-338-3p +UCCAGCAUCAGUGAUUUUGUUG +>hsa-miR-339-5p +UCCCUGUCCUCCAGGAGCUCACG +>hsa-miR-339-3p +UGAGCGCCUCGACGACAGAGCCG +>hsa-miR-335 +UCAAGAGCAAUAACGAAAAAUGU +>hsa-miR-133b +UUUGGUCCCCUUCAACCAGCUA +>hsa-miR-325 +CCUAGUAGGUGUCCAGUAAGUGU +>hsa-miR-345 +GCUGACUCCUAGUCCAGGGCUC +>hsa-miR-346 +UGUCUGCCCGCAUGCCUGCCUCU +>hsa-miR-384 +AUUCCUAGAAAUUGUUCAUA +>hsa-miR-196b +UAGGUAGUUUCCUGUUGUUGGG +>hsa-miR-422a +ACUGGACUUAGGGUCAGAAGGC +>hsa-miR-423-5p +UGAGGGGCAGAGAGCGAGACUUU +>hsa-miR-423-3p +AGCUCGGUCUGAGGCCCCUCAGU +>hsa-miR-424 +CAGCAGCAAUUCAUGUUUUGAA +>hsa-miR-425 +AAUGACACGAUCACUCCCGUUGA +>hsa-miR-18b +UAAGGUGCAUCUAGUGCAGUUAG +>hsa-miR-20b +CAAAGUGCUCAUAGUGCAGGUAG +>hsa-miR-448 +UUGCAUAUGUAGGAUGUCCCAU +>hsa-miR-429 +UAAUACUGUCUGGUAAAACCGU +>hsa-miR-449a +UGGCAGUGUAUUGUUAGCUGGU +>hsa-miR-450a +UUUUGCGAUGUGUUCCUAAUAU +>hsa-miR-431 +UGUCUUGCAGGCCGUCAUGCA +>hsa-miR-433 +AUCAUGAUGGGCUCCUCGGUGU +>hsa-miR-329 +AACACACCUGGUUAACCUCUUU +>hsa-miR-453 +AGGUUGUCCGUGGUGAGUUCGCA +>hsa-miR-451 +AAACCGUUACCAUUACUGAGUU +>hsa-miR-452 +AACUGUUUGCAGAGGAAACUGA +>hsa-miR-409-5p +AGGUUACCCGAGCAACUUUGCAU +>hsa-miR-409-3p +GAAUGUUGCUCGGUGAACCCCU +>hsa-miR-412 +ACUUCACCUGGUCCACUAGCCGU +>hsa-miR-410 +AAUAUAACACAGAUGGCCUGU +>hsa-miR-376b +AUCAUAGAGGAAAAUCCAUGUU +>hsa-miR-483-5p +AAGACGGGAGGAAAGAAGGGAG +>hsa-miR-483-3p +UCACUCCUCUCCUCCCGUCUU +>hsa-miR-484 +UCAGGCUCAGUCCCCUCCCGAU +>hsa-miR-485-5p +AGAGGCUGGCCGUGAUGAAUUC +>hsa-miR-485-3p +GUCAUACACGGCUCUCCUCUCU +>hsa-miR-486-5p +UCCUGUACUGAGCUGCCCCGAG +>hsa-miR-486-3p +CGGGGCAGCUCAGUACAGGAU +>hsa-miR-487a +AAUCAUACAGGGACAUCCAGUU +>hsa-miR-488 +UUGAAAGGCUAUUUCUUGGUC +>hsa-miR-489 +GUGACAUCACAUAUACGGCAGC +>hsa-miR-490-5p +CCAUGGAUCUCCAGGUGGGU +>hsa-miR-490-3p +CAACCUGGAGGACUCCAUGCUG +>hsa-miR-491-5p +AGUGGGGAACCCUUCCAUGAGG +>hsa-miR-491-3p +CUUAUGCAAGAUUCCCUUCUAC +>hsa-miR-511 +GUGUCUUUUGCUCUGCAGUCA +>hsa-miR-146b-5p +UGAGAACUGAAUUCCAUAGGCU +>hsa-miR-146b-3p +UGCCCUGUGGACUCAGUUCUGG +>hsa-miR-202 +AGAGGUAUAGGGCAUGGGAA +>hsa-miR-492 +AGGACCUGCGGGACAAGAUUCUU +>hsa-miR-493 +UGAAGGUCUACUGUGUGCCAGG +>hsa-miR-432 +UCUUGGAGUAGGUCAUUGGGUGG +>hsa-miR-494 +UGAAACAUACACGGGAAACCUC +>hsa-miR-495 +AAACAAACAUGGUGCACUUCUU +>hsa-miR-496 +UGAGUAUUACAUGGCCAAUCUC +>hsa-miR-193b +AACUGGCCCUCAAAGUCCCGCU +>hsa-miR-497 +CAGCAGCACACUGUGGUUUGU +>hsa-miR-181d +AACAUUCAUUGUUGUCGGUGGGU +>hsa-miR-512-5p +CACUCAGCCUUGAGGGCACUUUC +>hsa-miR-512-3p +AAGUGCUGUCAUAGCUGAGGUC +>hsa-miR-498 +UUUCAAGCCAGGGGGCGUUUUUC +>hsa-miR-520e +AAAGUGCUUCCUUUUUGAGGG +>hsa-miR-515-5p +UUCUCCAAAAGAAAGCACUUUCUG +>hsa-miR-515-3p +GAGUGCCUUCUUUUGGAGCGUU +>hsa-miR-519e +AAGUGCCUCCUUUUAGAGUGUU +>hsa-miR-520f +AAGUGCUUCCUUUUAGAGGGUU 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+>hsa-miR-1200 +CUCCUGAGCCAUUCUGAGCCUC +>hsa-miR-1201 +AGCCUGAUUAAACACAUGCUCUGA +>hsa-miR-1202 +GUGCCAGCUGCAGUGGGGGAG +>hsa-miR-1203 +CCCGGAGCCAGGAUGCAGCUC +>hsa-miR-663b +GGUGGCCCGGCCGUGCCUGAGG +>hsa-miR-1204 +UCGUGGCCUGGUCUCCAUUAU +>hsa-miR-1205 +UCUGCAGGGUUUGCUUUGAG +>hsa-miR-1206 +UGUUCAUGUAGAUGUUUAAGC +>hsa-miR-1207-5p +UGGCAGGGAGGCUGGGAGGGG +>hsa-miR-1207-3p +UCAGCUGGCCCUCAUUUC +>hsa-miR-1208 +UCACUGUUCAGACAGGCGGA +>hsa-miR-548e +AAAAACUGAGACUACUUUUGCA +>hsa-miR-548j +AAAAGUAAUUGCGGUCUUUGGU +>hsa-miR-1285 +UCUGGGCAACAAAGUGAGACCU +>hsa-miR-1286 +UGCAGGACCAAGAUGAGCCCU +>hsa-miR-1287 +UGCUGGAUCAGUGGUUCGAGUC +>hsa-miR-1289 +UGGAGUCCAGGAAUCUGCAUUUU +>hsa-miR-1290 +UGGAUUUUUGGAUCAGGGA +>hsa-miR-1291 +UGGCCCUGACUGAAGACCAGCAGU +>hsa-miR-548k +AAAAGUACUUGCGGAUUUUGCU +>hsa-miR-1293 +UGGGUGGUCUGGAGAUUUGUGC +>hsa-miR-1294 +UGUGAGGUUGGCAUUGUUGUCU +>hsa-miR-1295 +UUAGGCCGCAGAUCUGGGUGA +>hsa-miR-1297 +UUCAAGUAAUUCAGGUG +>hsa-miR-1299 +UUCUGGAAUUCUGUGUGAGGGA +>hsa-miR-1300 +UUGAGAAGGAGGCUGCUG +>hsa-miR-548l +AAAAGUAUUUGCGGGUUUUGUC +>hsa-miR-1302 +UUGGGACAUACUUAUGCUAAA +>hsa-miR-1303 +UUUAGAGACGGGGUCUUGCUCU +>hsa-miR-1304 +UUUGAGGCUACAGUGAGAUGUG +>hsa-miR-1305 +UUUUCAACUCUAAUGGGAGAGA +>hsa-miR-1243 +AACUGGAUCAAUUAUAGGAGUG +>hsa-miR-548f +AAAAACUGUAAUUACUUUU +>hsa-miR-1244 +AAGUAGUUGGUUUGUAUGAGAUGGUU +>hsa-miR-1245 +AAGUGAUCUAAAGGCCUACAU +>hsa-miR-1246 +AAUGGAUUUUUGGAGCAGG +>hsa-miR-1247 +ACCCGUCCCGUUCGUCCCCGGA +>hsa-miR-1248 +ACCUUCUUGUAUAAGCACUGUGCUAAA +>hsa-miR-1249 +ACGCCCUUCCCCCCCUUCUUCA +>hsa-miR-1250 +ACGGUGCUGGAUGUGGCCUUU +>hsa-miR-1251 +ACUCUAGCUGCCAAAGGCGCU +>hsa-miR-1253 +AGAGAAGAAGAUCAGCCUGCA +>hsa-miR-1254 +AGCCUGGAAGCUGGAGCCUGCAGU +>hsa-miR-1255a +AGGAUGAGCAAAGAAAGUAGAUU +>hsa-miR-1256 +AGGCAUUGACUUCUCACUAGCU +>hsa-miR-1257 +AGUGAAUGAUGGGUUCUGACC +>hsa-miR-1258 +AGUUAGGAUUAGGUCGUGGAA +>hsa-miR-1259 +AUAUAUGAUGACUUAGCUUUU +>hsa-miR-1260 +AUCCCACCUCUGCCACCA +>hsa-miR-548g +AAAACUGUAAUUACUUUUGUAC +>hsa-miR-1261 +AUGGAUAAGGCUUUGGCUU +>hsa-miR-1262 +AUGGGUGAAUUUGUAGAAGGAU +>hsa-miR-1263 +AUGGUACCCUGGCAUACUGAGU +>hsa-miR-548n +CAAAAGUAAUUGUGGAUUUUGU +>hsa-miR-548m +CAAAGGUAUUUGUGGUUUUUG +>hsa-miR-1265 +CAGGAUGUGGUCAAGUGUUGUU +>hsa-miR-548o +CCAAAACUGCAGUUACUUUUGC +>hsa-miR-1266 +CCUCAGGGCUGUAGAACAGGGCU +>hsa-miR-1267 +CCUGUUGAAGUGUAAUCCCCA +>hsa-miR-1268 +CGGGCGUGGUGGUGGGGG +>hsa-miR-1269 +CUGGACUGAGCCGUGCUACUGG +>hsa-miR-1270 +CUGGAGAUAUGGAAGAGCUGUGU +>hsa-miR-1272 +GAUGAUGAUGGCAGCAAAUUCUGAAA +>hsa-miR-1273 +GGGCGACAAAGCAAGACUCUUUCUU +>hsa-miR-1274a +GUCCCUGUUCAGGCGCCA +>hsa-miR-548h +AAAAGUAAUCGCGGUUUUUGUC +>hsa-miR-1275 +GUGGGGGAGAGGCUGUC +>hsa-miR-1276 +UAAAGAGCCCUGUGGAGACA +>hsa-miR-302e +UAAGUGCUUCCAUGCUU +>hsa-miR-302f +UAAUUGCUUCCAUGUUU +>hsa-miR-1277 +UACGUAGAUAUAUAUGUAUUUU +>hsa-miR-548p +UAGCAAAAACUGCAGUUACUUU +>hsa-miR-548i +AAAAGUAAUUGCGGAUUUUGCC +>hsa-miR-1278 +UAGUACUGUGCAUAUCAUCUAU +>hsa-miR-1279 +UCAUAUUGCUUCUUUCU +>hsa-miR-1274b +UCCCUGUUCGGGCGCCA +>hsa-miR-1281 +UCGCCUCCUCCUCUCCC +>hsa-miR-1282 +UCGUUUGCCUUUUUCUGCUU +>hsa-miR-1284 +UCUAUACAGACCCUGGCUUUUC +>hsa-miR-1288 +UGGACUGCCCUGAUCUGGAGA +>hsa-miR-1292 +UGGGAACGGGUUCCGGCAGACGCUG +>hsa-miR-1252 +AGAAGGAAAUUGAAUUCAUUUA +>hsa-miR-1255b +CGGAUGAGCAAAGAAAGUGGUU +>hsa-miR-1280 +UCCCACCGCUGCCACCC +>hsa-miR-1308 +GCAUGGGUGGUUCAGUGG +>hsa-miR-664 +UAUUCAUUUAUCCCCAGCCUACA +>hsa-miR-1306 +ACGUUGGCUCUGGUGGUG +>hsa-miR-1307 +ACUCGGCGUGGCGUCGGUCGUG +>hsa-miR-513b +UUCACAAGGAGGUGUCAUUUAU +>hsa-miR-513c +UUCUCAAGGAGGUGUCGUUUAU +>hsa-miR-1321 +CAGGGAGGUGAAUGUGAU +>hsa-miR-1322 +GAUGAUGCUGCUGAUGCUG +>hsa-miR-720 +UCUCGCUGGGGCCUCCA +>hsa-miR-1197 +UAGGACACAUGGUCUACUUCU +>hsa-miR-1324 +CCAGACAGAAUUCUAUGCACUUUC +>hsa-miR-320d +AAAAGCUGGGUUGAGAGGA +>hsa-miR-1825 +UCCAGUGCCCUCCUCUCC +>hsa-miR-1826 +AUUGAUCAUCGACACUUCGAACGCAAU +>hsa-miR-1827 +UGAGGCAGUAGAUUGAAU diff --git a/modules/local/pita/templates/known_mirs/mouse_mirs.fasta b/modules/local/pita/templates/known_mirs/mouse_mirs.fasta new file mode 100644 index 00000000..c6c57b41 --- /dev/null +++ b/modules/local/pita/templates/known_mirs/mouse_mirs.fasta @@ -0,0 +1,982 @@ +>mmu-let-7g +UGAGGUAGUAGUUUGUACAGUU +>mmu-let-7i +UGAGGUAGUAGUUUGUGCUGUU +>mmu-miR-1 +UGGAAUGUAAAGAAGUAUGUAU +>mmu-miR-15b +UAGCAGCACAUCAUGGUUUACA +>mmu-miR-23b +AUCACAUUGCCAGGGAUUACC +>mmu-miR-27b +UUCACAGUGGCUAAGUUCUGC +>mmu-miR-29b +UAGCACCAUUUGAAAUCAGUGUU +>mmu-miR-30a +UGUAAACAUCCUCGACUGGAAG +>mmu-miR-30b +UGUAAACAUCCUACACUCAGCU +>mmu-miR-99a +AACCCGUAGAUCCGAUCUUGUG +>mmu-miR-99b +CACCCGUAGAACCGACCUUGCG +>mmu-miR-101a +UACAGUACUGUGAUAACUGAA +>mmu-miR-124 +UAAGGCACGCGGUGAAUGCC +>mmu-miR-125a-5p +UCCCUGAGACCCUUUAACCUGUGA +>mmu-miR-125a-3p +ACAGGUGAGGUUCUUGGGAGCC +>mmu-miR-125b-5p +UCCCUGAGACCCUAACUUGUGA +>mmu-miR-126-5p +CAUUAUUACUUUUGGUACGCG +>mmu-miR-126-3p +UCGUACCGUGAGUAAUAAUGCG +>mmu-miR-127 +UCGGAUCCGUCUGAGCUUGGCU +>mmu-miR-128 +UCACAGUGAACCGGUCUCUUU +>mmu-miR-130a +CAGUGCAAUGUUAAAAGGGCAU +>mmu-miR-9 +UCUUUGGUUAUCUAGCUGUAUGA +>mmu-miR-132 +UAACAGUCUACAGCCAUGGUCG +>mmu-miR-133a +UUUGGUCCCCUUCAACCAGCUG +>mmu-miR-134 +UGUGACUGGUUGACCAGAGGGG +>mmu-miR-135a +UAUGGCUUUUUAUUCCUAUGUGA +>mmu-miR-136 +ACUCCAUUUGUUUUGAUGAUGG +>mmu-miR-137 +UUAUUGCUUAAGAAUACGCGUAG +>mmu-miR-138 +AGCUGGUGUUGUGAAUCAGGCCG +>mmu-miR-140 +CAGUGGUUUUACCCUAUGGUAG +>mmu-miR-141 +UAACACUGUCUGGUAAAGAUGG +>mmu-miR-142-5p +CAUAAAGUAGAAAGCACUACU +>mmu-miR-142-3p +UGUAGUGUUUCCUACUUUAUGGA +>mmu-miR-144 +UACAGUAUAGAUGAUGUACU +>mmu-miR-145 +GUCCAGUUUUCCCAGGAAUCCCU +>mmu-miR-146a +UGAGAACUGAAUUCCAUGGGUU +>mmu-miR-149 +UCUGGCUCCGUGUCUUCACUCCC +>mmu-miR-150 +UCUCCCAACCCUUGUACCAGUG +>mmu-miR-151-5p +UCGAGGAGCUCACAGUCUAGU +>mmu-miR-151-3p +CUAGACUGAGGCUCCUUGAGG +>mmu-miR-152 +UCAGUGCAUGACAGAACUUGG +>mmu-miR-153 +UUGCAUAGUCACAAAAGUGAUC +>mmu-miR-154 +UAGGUUAUCCGUGUUGCCUUCG +>mmu-miR-155 +UUAAUGCUAAUUGUGAUAGGGGU +>mmu-miR-10b +UACCCUGUAGAACCGAAUUUGUG +>mmu-miR-129-5p +CUUUUUGCGGUCUGGGCUUGC +>mmu-miR-181a +AACAUUCAACGCUGUCGGUGAGU +>mmu-miR-182 +UUUGGCAAUGGUAGAACUCACACCG +>mmu-miR-183 +UAUGGCACUGGUAGAAUUCACU +>mmu-miR-184 +UGGACGGAGAACUGAUAAGGGU +>mmu-miR-185 +UGGAGAGAAAGGCAGUUCCUGA +>mmu-miR-186 +CAAAGAAUUCUCCUUUUGGGCU +>mmu-miR-187 +UCGUGUCUUGUGUUGCAGCCGG +>mmu-miR-188-5p +CAUCCCUUGCAUGGUGGAGGG +>mmu-miR-188-3p +CUCCCACAUGCAGGGUUUGCA +>mmu-miR-24 +UGGCUCAGUUCAGCAGGAACAG +>mmu-miR-190 +UGAUAUGUUUGAUAUAUUAGGU +>mmu-miR-191 +CAACGGAAUCCCAAAAGCAGCUG +>mmu-miR-193 +AACUGGCCUACAAAGUCCCAGU +>mmu-miR-194 +UGUAACAGCAACUCCAUGUGGA +>mmu-miR-195 +UAGCAGCACAGAAAUAUUGGC +>mmu-miR-199a-5p +CCCAGUGUUCAGACUACCUGUUC +>mmu-miR-199a-3p +ACAGUAGUCUGCACAUUGGUUA +>mmu-miR-200b +UAAUACUGCCUGGUAAUGAUGA +>mmu-miR-201 +UACUCAGUAAGGCAUUGUUCUU +>mmu-miR-202-5p +UUCCUAUGCAUAUACUUCUUU +>mmu-miR-202-3p +AGAGGUAUAGCGCAUGGGAAGA +>mmu-miR-203 +GUGAAAUGUUUAGGACCACUAG +>mmu-miR-204 +UUCCCUUUGUCAUCCUAUGCCU +>mmu-miR-205 +UCCUUCAUUCCACCGGAGUCUG +>mmu-miR-206 +UGGAAUGUAAGGAAGUGUGUGG +>mmu-miR-207 +GCUUCUCCUGGCUCUCCUCCCUC +>mmu-miR-122 +UGGAGUGUGACAAUGGUGUUUG +>mmu-miR-143 +UGAGAUGAAGCACUGUAGCUC +>mmu-miR-30e +UGUAAACAUCCUUGACUGGAAG +>mmu-miR-290-5p +ACUCAAACUAUGGGGGCACUUU +>mmu-miR-290-3p +AAAGUGCCGCCUAGUUUUAAGCCC +>mmu-miR-291a-5p +CAUCAAAGUGGAGGCCCUCUCU +>mmu-miR-291a-3p +AAAGUGCUUCCACUUUGUGUGC +>mmu-miR-292-5p +ACUCAAACUGGGGGCUCUUUUG +>mmu-miR-292-3p +AAAGUGCCGCCAGGUUUUGAGUGU +>mmu-miR-293 +AGUGCCGCAGAGUUUGUAGUGU +>mmu-miR-294 +AAAGUGCUUCCCUUUUGUGUGU +>mmu-miR-295 +AAAGUGCUACUACUUUUGAGUCU +>mmu-miR-296-5p +AGGGCCCCCCCUCAAUCCUGU +>mmu-miR-296-3p +GAGGGUUGGGUGGAGGCUCUCC +>mmu-miR-297a +AUGUAUGUGUGCAUGUGCAUGU +>mmu-miR-298 +GGCAGAGGAGGGCUGUUCUUCCC +>mmu-miR-299 +UAUGUGGGACGGUAAACCGCUU +>mmu-miR-300 +UAUGCAAGGGCAAGCUCUCUUC +>mmu-miR-301a +CAGUGCAAUAGUAUUGUCAAAGC +>mmu-miR-302a +UAAGUGCUUCCAUGUUUUGGUGA +>mmu-miR-34c +AGGCAGUGUAGUUAGCUGAUUGC +>mmu-miR-34b-5p +AGGCAGUGUAAUUAGCUGAUUGU +>mmu-miR-34b-3p +AAUCACUAACUCCACUGCCAUC +>mmu-let-7d +AGAGGUAGUAGGUUGCAUAGUU +>mmu-miR-106a +CAAAGUGCUAACAGUGCAGGUAG +>mmu-miR-106b +UAAAGUGCUGACAGUGCAGAU +>mmu-miR-130b +CAGUGCAAUGAUGAAAGGGCAU +>mmu-miR-19b +UGUGCAAAUCCAUGCAAAACUGA +>mmu-miR-30c +UGUAAACAUCCUACACUCUCAGC +>mmu-miR-30d +UGUAAACAUCCCCGACUGGAAG +>mmu-miR-148a +UCAGUGCACUACAGAACUUUGU +>mmu-miR-192 +CUGACCUAUGAAUUGACAGCC +>mmu-miR-196a +UAGGUAGUUUCAUGUUGUUGGG +>mmu-miR-200a +UAACACUGUCUGGUAACGAUGU +>mmu-miR-208a +AUAAGACGAGCAAAAAGCUUGU +>mmu-let-7a +UGAGGUAGUAGGUUGUAUAGUU +>mmu-let-7b +UGAGGUAGUAGGUUGUGUGGUU +>mmu-let-7c +UGAGGUAGUAGGUUGUAUGGUU +>mmu-let-7e +UGAGGUAGGAGGUUGUAUAGUU +>mmu-let-7f +UGAGGUAGUAGAUUGUAUAGUU +>mmu-miR-15a +UAGCAGCACAUAAUGGUUUGUG +>mmu-miR-16 +UAGCAGCACGUAAAUAUUGGCG +>mmu-miR-18a +UAAGGUGCAUCUAGUGCAGAUAG +>mmu-miR-20a +UAAAGUGCUUAUAGUGCAGGUAG +>mmu-miR-21 +UAGCUUAUCAGACUGAUGUUGA +>mmu-miR-22 +AAGCUGCCAGUUGAAGAACUGU +>mmu-miR-23a +AUCACAUUGCCAGGGAUUUCC +>mmu-miR-26a +UUCAAGUAAUCCAGGAUAGGCU +>mmu-miR-26b +UUCAAGUAAUUCAGGAUAGGU +>mmu-miR-29a +UAGCACCAUCUGAAAUCGGUUA +>mmu-miR-29c +UAGCACCAUUUGAAAUCGGUUA +>mmu-miR-27a +UUCACAGUGGCUAAGUUCCGC +>mmu-miR-31 +AGGCAAGAUGCUGGCAUAGCUG +>mmu-miR-92a +UAUUGCACUUGUCCCGGCCUG +>mmu-miR-93 +CAAAGUGCUGUUCGUGCAGGUAG +>mmu-miR-96 +UUUGGCACUAGCACAUUUUUGCU +>mmu-miR-34a +UGGCAGUGUCUUAGCUGGUUGU +>mmu-miR-129-3p +AAGCCCUUACCCCAAAAAGCAU +>mmu-miR-98 +UGAGGUAGUAAGUUGUAUUGUU +>mmu-miR-103 +AGCAGCAUUGUACAGGGCUAUGA +>mmu-miR-322 +CAGCAGCAAUUCAUGUUUUGGA +>mmu-miR-323-5p +AGGUGGUCCGUGGCGCGUUCGC +>mmu-miR-323-3p +CACAUUACACGGUCGACCUCU +>mmu-miR-324-5p +CGCAUCCCCUAGGGCAUUGGUGU +>mmu-miR-324-3p +CCACUGCCCCAGGUGCUGCU +>mmu-miR-325 +UUUAUUGAGCACCUCCUAUCAA +>mmu-miR-326 +CCUCUGGGCCCUUCCUCCAGU +>mmu-miR-328 +CUGGCCCUCUCUGCCCUUCCGU +>mmu-miR-329 +AACACACCCAGCUAACCUUUUU +>mmu-miR-330 +UCUCUGGGCCUGUGUCUUAGGC +>mmu-miR-331-5p +CUAGGUAUGGUCCCAGGGAUCC +>mmu-miR-331-3p +GCCCCUGGGCCUAUCCUAGAA +>mmu-miR-337-5p +GAACGGCGUCAUGCAGGAGUU +>mmu-miR-337-3p +UUCAGCUCCUAUAUGAUGCCU +>mmu-miR-148b +UCAGUGCAUCACAGAACUUUGU +>mmu-miR-338-5p +AACAAUAUCCUGGUGCUGAGUG +>mmu-miR-338-3p +UCCAGCAUCAGUGAUUUUGUUG +>mmu-miR-339-5p +UCCCUGUCCUCCAGGAGCUCACG +>mmu-miR-339-3p +UGAGCGCCUCGGCGACAGAGCCG +>mmu-miR-340-5p +UUAUAAAGCAAUGAGACUGAUU +>mmu-miR-340-3p +UCCGUCUCAGUUACUUUAUAGC +>mmu-miR-341 +UCGGUCGAUCGGUCGGUCGGU +>mmu-miR-342-5p +AGGGGUGCUAUCUGUGAUUGAG +>mmu-miR-342-3p +UCUCACACAGAAAUCGCACCCGU +>mmu-miR-344 +UGAUCUAGCCAAAGCCUGACUGU +>mmu-miR-345-5p +GCUGACCCCUAGUCCAGUGCUU +>mmu-miR-345-3p +CCUGAACUAGGGGUCUGGAGAC +>mmu-miR-346 +UGUCUGCCCGAGUGCCUGCCUCU +>mmu-miR-350 +UUCACAAAGCCCAUACACUUUC +>mmu-miR-351 +UCCCUGAGGAGCCCUUUGAGCCUG +>mmu-miR-135b +UAUGGCUUUUCAUUCCUAUGUGA +>mmu-miR-101b +UACAGUACUGUGAUAGCUGAA +>mmu-miR-107 +AGCAGCAUUGUACAGGGCUAUCA +>mmu-miR-10a +UACCCUGUAGAUCCGAAUUUGUG +>mmu-miR-17 +CAAAGUGCUUACAGUGCAGGUAG +>mmu-miR-19a +UGUGCAAAUCUAUGCAAAACUGA +>mmu-miR-25 +CAUUGCACUUGUCUCGGUCUGA +>mmu-miR-28 +AAGGAGCUCACAGUCUAUUGAG +>mmu-miR-32 +UAUUGCACAUUACUAAGUUGCA +>mmu-miR-100 +AACCCGUAGAUCCGAACUUGUG +>mmu-miR-139-5p +UCUACAGUGCACGUGUCUCCAG +>mmu-miR-139-3p +UGGAGACGCGGCCCUGUUGGAG +>mmu-miR-200c +UAAUACUGCCGGGUAAUGAUGGA +>mmu-miR-210 +CUGUGCGUGUGACAGCGGCUGA +>mmu-miR-212 +UAACAGUCUCCAGUCACGGCCA +>mmu-miR-214 +ACAGCAGGCACAGACAGGCAGU +>mmu-miR-216a +UAAUCUCAGCUGGCAACUGUGA +>mmu-miR-218 +UUGUGCUUGAUCUAACCAUGU +>mmu-miR-219 +UGAUUGUCCAAACGCAAUUCU +>mmu-miR-223 +UGUCAGUUUGUCAAAUACCCCA +>mmu-miR-320 +AAAAGCUGGGUUGAGAGGGCGA +>mmu-miR-33 +GUGCAUUGUAGUUGCAUUGCA +>mmu-miR-211 +UUCCCUUUGUCAUCCUUUGCCU +>mmu-miR-221 +AGCUACAUUGUCUGCUGGGUUUC +>mmu-miR-222 +AGCUACAUCUGGCUACUGGGU +>mmu-miR-224 +UAAGUCACUAGUGGUUCCGUU +>mmu-miR-199b +ACAGUAGUCUGCACAUUGGUUA +>mmu-miR-181b +AACAUUCAUUGCUGUCGGUGGGU +>mmu-miR-181c +AACAUUCAACCUGUCGGUGAGU +>mmu-miR-125b-3p +ACGGGUUAGGCUCUUGGGAGCU +>mmu-miR-7a +UGGAAGACUAGUGAUUUUGUUGU +>mmu-miR-7b +UGGAAGACUUGUGAUUUUGUUGU +>mmu-miR-217 +UACUGCAUCAGGAACUGACUGGA +>mmu-miR-361 +UUAUCAGAAUCUCCAGGGGUAC +>mmu-miR-362-5p +AAUCCUUGGAACCUAGGUGUGAAU +>mmu-miR-362-3p +AACACACCUGUUCAAGGAUUCA +>mmu-miR-363 +AAUUGCACGGUAUCCAUCUGUA +>mmu-miR-365 +UAAUGCCCCUAAAAAUCCUUAU +>mmu-miR-375 +UUUGUUCGUUCGGCUCGCGUGA 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+AAACAAACAAACAGACCAAAUU +>mmu-miR-1193 +UAGGUCACCCGUUUUACUAUC +>mmu-miR-1194 +GAAUGAGUAACUGCUAGAUCCU +>mmu-miR-669e +UGUCUUGUGUGUGCAUGUUCAU +>mmu-miR-467g +UAUACAUACACACACAUAUAU +>mmu-miR-467h +AUAAGUGUGUGCAUGUAUAUGU +>mmu-miR-1195 +UGAGUUCGAGGCCAGCCUGCUCA +>mmu-miR-1196 +AAAUCUACCUGCCUCUGCCU +>mmu-miR-1197 +UAGGACACAUGGUCUACUUCU +>mmu-miR-1198 +UAUGUGUUCCUGGCUGGCUUGG +>mmu-miR-1199 +UCUGAGUCCCGGUCGCGCGG diff --git a/modules/local/pita/templates/known_mirs/worm_mirs.fasta b/modules/local/pita/templates/known_mirs/worm_mirs.fasta new file mode 100644 index 00000000..1e70dc83 --- /dev/null +++ b/modules/local/pita/templates/known_mirs/worm_mirs.fasta @@ -0,0 +1,308 @@ +>cel-let-7 +UGAGGUAGUAGGUUGUAUAGUU +>cel-lin-4 +UCCCUGAGACCUCAAGUGUGA +>cel-miR-1 +UGGAAUGUAAAGAAGUAUGUA +>cel-miR-2 +UAUCACAGCCAGCUUUGAUGUGC +>cel-miR-34 +AGGCAGUGUGGUUAGCUGGUUG +>cel-miR-35 +UCACCGGGUGGAAACUAGCAGU +>cel-miR-36 +UCACCGGGUGAAAAUUCGCAUG +>cel-miR-37 +UCACCGGGUGAACACUUGCAGU +>cel-miR-38 +UCACCGGGAGAAAAACUGGAGU +>cel-miR-39 +UCACCGGGUGUAAAUCAGCUUG +>cel-miR-40 +UCACCGGGUGUACAUCAGCUAA +>cel-miR-41 +UCACCGGGUGAAAAAUCACCUA +>cel-miR-42 +UCACCGGGUUAACAUCUACAGA +>cel-miR-43 +UAUCACAGUUUACUUGCUGUCGC +>cel-miR-44 +UGACUAGAGACACAUUCAGCU +>cel-miR-45 +UGACUAGAGACACAUUCAGCU +>cel-miR-46 +UGUCAUGGAGUCGCUCUCUUCA +>cel-miR-47 +UGUCAUGGAGGCGCUCUCUUCA +>cel-miR-48 +UGAGGUAGGCUCAGUAGAUGCGA +>cel-miR-49 +AAGCACCACGAGAAGCUGCAGA +>cel-miR-50 +UGAUAUGUCUGGUAUUCUUGGG +>cel-miR-51 +UACCCGUAGCUCCUAUCCAUGUU +>cel-miR-52 +CACCCGUACAUAUGUUUCCGUGCU +>cel-miR-53 +CACCCGUACAUUUGUUUCCGUGCU +>cel-miR-54 +UACCCGUAAUCUUCAUAAUCCGAG +>cel-miR-55 +UACCCGUAUAAGUUUCUGCUGAG +>cel-miR-56 +UACCCGUAAUGUUUCCGCUGAG +>cel-miR-57 +UACCCUGUAGAUCGAGCUGUGUGU +>cel-miR-58 +UGAGAUCGUUCAGUACGGCAAU +>cel-miR-59 +UCGAAUCGUUUAUCAGGAUGAUG +>cel-miR-60 +UAUUAUGCACAUUUUCUAGUUCA +>cel-miR-61 +UGACUAGAACCGUUACUCAUC +>cel-miR-62 +UGAUAUGUAAUCUAGCUUACAG +>cel-miR-63 +UAUGACACUGAAGCGAGUUGGAAA +>cel-miR-64 +UAUGACACUGAAGCGUUACCGAA +>cel-miR-65 +UAUGACACUGAAGCGUAACCGAA +>cel-miR-66 +CAUGACACUGAUUAGGGAUGUGA +>cel-miR-67 +UCACAACCUCCUAGAAAGAGUAGA +>cel-miR-70 +UAAUACGUCGUUGGUGUUUCCAU +>cel-miR-71 +UGAAAGACAUGGGUAGUGA +>cel-miR-72 +AGGCAAGAUGUUGGCAUAGCUGA +>cel-miR-73 +UGGCAAGAUGUAGGCAGUUCAGU +>cel-miR-74 +UGGCAAGAAAUGGCAGUCUACA +>cel-miR-75 +UUAAAGCUACCAACCGGCUUCA +>cel-miR-76 +UUCGUUGUUGAUGAAGCCUUGA +>cel-miR-77 +UUCAUCAGGCCAUAGCUGUCCA +>cel-miR-78 +UGGAGGCCUGGUUGUUUGUGC +>cel-miR-79 +AUAAAGCUAGGUUACCAAAGCU +>cel-miR-227 +AGCUUUCGACAUGAUUCUGAAC +>cel-miR-80 +UGAGAUCAUUAGUUGAAAGCCGA +>cel-miR-81 +UGAGAUCAUCGUGAAAGCUAGU +>cel-miR-82 +UGAGAUCAUCGUGAAAGCCAGU +>cel-miR-83 +UAGCACCAUAUAAAUUCAGUAA +>cel-miR-84 +UGAGGUAGUAUGUAAUAUUGUA +>cel-miR-85 +UACAAAGUAUUUGAAAAGUCGUGC +>cel-miR-86 +UAAGUGAAUGCUUUGCCACAGUC +>cel-miR-87 +GUGAGCAAAGUUUCAGGUGUGC +>cel-miR-90 +UGAUAUGUUGUUUGAAUGCCCCU +>cel-miR-124 +UAAGGCACGCGGUGAAUGCCA +>cel-miR-228 +AAUGGCACUGCAUGAAUUCACGG +>cel-miR-229 +AAUGACACUGGUUAUCUUUUCCAUCG +>cel-miR-230 +GUAUUAGUUGUGCGACCAGGAGA +>cel-miR-231 +UAAGCUCGUGAUCAACAGGCAGAA +>cel-miR-232 +UAAAUGCAUCUUAACUGCGGUGA +>cel-miR-233 +UUGAGCAAUGCGCAUGUGCGG +>cel-miR-234 +UUAUUGCUCGAGAAUACCCUU +>cel-miR-235 +UAUUGCACUCUCCCCGGCCUGA +>cel-miR-236 +UAAUACUGUCAGGUAAUGACGCU +>cel-miR-237 +UCCCUGAGAAUUCUCGAACAGCU +>cel-miR-238 +UUUGUACUCCGAUGCCAUUCAGA +>cel-miR-239a +UUUGUACUACACAUAGGUACUGG +>cel-miR-239b +UUUGUACUACACAAAAGUACUG +>cel-miR-240 +UACUGGCCCCCAAAUCUUCGCU +>cel-miR-241 +UGAGGUAGGUGCGAGAAAUGA +>cel-miR-242 +UUGCGUAGGCCUUUGCUUCGA +>cel-miR-243 +CGGUACGAUCGCGGCGGGAUAUC +>cel-miR-244 +UCUUUGGUUGUACAAAGUGGUAUG +>cel-miR-245 +AUUGGUCCCCUCCAAGUAGCUC +>cel-miR-246 +UUACAUGUUUCGGGUAGGAGC +>cel-miR-247 +UGACUAGAGCCUAUUCUCUUCU +>cel-miR-248 +AUACACGUGCACGGAUAACGCUCA +>cel-miR-249 +UCACAGGACUUUUGAGCGUUGCC +>cel-miR-250 +AAUCACAGUCAACUGUUGGCA +>cel-miR-251 +UUAAGUAGUGGUGCCGCUCUUAUU +>cel-miR-252 +AUAAGUAGUAGUGCCGCAGGUAA +>cel-miR-253 +UUAGUAGGCGUUGUGGGAAGG +>cel-miR-254 +UGCAAAUCUUUCGCGACUGUAGG +>cel-miR-255 +AAACUGAAGAGAUUUUUUACAG +>cel-miR-256 +UGGAAUGCAUAGAAGACUGUA +>cel-miR-257 +GAGUAUCAGGAGUACCCAGUGA +>cel-miR-258 +GGUUUUGAGAGGAAUCCUUUU +>cel-miR-259 +AAAUCUCAUCCUAAUCUGGUAGCA +>cel-miR-260 +GUGAUGUCGAACUCUUGUAG +>cel-miR-261 +UAGCUUUUUAGUUUUCACG +>cel-miR-262 +GUUUCUCGAUGUUUUCUGAU +>cel-miR-264 +GGCGGGUGGUUGUUGUUAUG +>cel-miR-265 +UGAGGGAGGAAGGGUGGUAU +>cel-miR-266 +AGGCAAGACUUUGGCAAAGC +>cel-miR-267 +CCCGUGAAGUGUCUGCUGCA +>cel-miR-268 +GGCAAGAAUUAGAAGCAGUUUGGU +>cel-miR-269 +GGCAAGACUCUGGCAAAACU +>cel-miR-270 +GGCAUGAUGUAGCAGUGGAG +>cel-miR-271 +UCGCCGGGUGGGAAAGCAUU +>cel-miR-272 +UGUAGGCAUGGGUGUUUG +>cel-miR-273 +UGCCCGUACUGUGUCGGCUG +>cel-miR-353 +CAAUUGCCAUGUGUUGGUAUU +>cel-miR-354 +ACCUUGUUUGUUGCUGCUCCU +>cel-miR-355 +UUUGUUUUAGCCUGAGCUAUG +>cel-miR-356 +UUGAGCAACGCGAACAAAUCA +>cel-miR-357 +UAAAUGCCAGUCGUUGCAGGAGU +>cel-miR-358 +AUUGGUAUCCCUGUCAAGGUC +>cel-miR-359 +UCACUGGUCUUUCUCUGACGAA +>cel-miR-360 +UGACCGUAAUCCCGUUCACAA +>cel-lsy-6 +UUUUGUAUGAGACGCAUUUCG +>cel-miR-392 +UAUCAUCGAUCACGUGUGAUGA +>cel-miR-784 +UGGCACAAUCUGCGUACGUAGA +>cel-miR-785 +UAAGUGAAUUGUUUUGUGUAGA +>cel-miR-786 +UAAUGCCCUGAAUGAUGUUCAAU +>cel-miR-787 +UAAGCUCGUUUUAGUAUCUUUCG +>cel-miR-788 +UCCGCUUCUAACUUCCAUUUGCAG +>cel-miR-789 +UCCCUGCCUGGGUCACCAAUUGU +>cel-miR-790 +CUUGGCACUCGCGAACACCGCG +>cel-miR-791 +UUUGGCACUCCGCAGAUAAGGCA +>cel-miR-792 +UUGAAAUCUCUUCAACUUUCAGA +>cel-miR-793 +UGAGGUAUCUUAGUUAGACAGA +>cel-miR-794 +UGAGGUAAUCAUCGUUGUCACU +>cel-miR-795 +UGAGGUAGAUUGAUCAGCGAGCUU +>cel-miR-796 +UGGAAUGUAGUUGAGGUUAGUAA +>cel-miR-797 +UAUCACAGCAAUCACAAUGAGAAGA +>cel-miR-798 +UAAGCCUUACAUAUUGACUGA +>cel-miR-799 +UGAACCCUGAUAAAGCUAGUGG +>cel-miR-800 +CAAACUCGGAAAUUGUCUGCCG +>cel-miR-1018 +AGAGAGAUCAUUGGACUUACAG +>cel-miR-1019 +CUGUAAUUCCACAUUGCUUUCCAG +>cel-miR-1020 +AUUAUUCUGUGACACUUUCAG +>cel-miR-1021 +AAGUGAGAUCAUGUGAAAUCCUCGG +>cel-miR-1022 +AAGAUCAUUGUUAGGACGCCAUC +>cel-miR-1817 +UAGCCAAUGUCUUCUCUAUCAUG +>cel-miR-1818 +UGUGGUCUUCAUGCCAUGAUUUU +>cel-miR-1819 +UGGAAUGAUUGAGCUUGAUGGA +>cel-miR-1820 +UUUUGAUUGUUUUUCGAUGAUGUUC +>cel-miR-1821 +UGAGGUCUUAUAGUUAGGUAG +>cel-miR-1822 +GAGCUGCCCUCAGAAAAACUCU +>cel-miR-1823 +UACUGGAAGUGUUUAGGAGUAA +>cel-miR-1824 +UGGCAGUGUUUCUCCCCCAACUU +>cel-miR-1828 +ACUGGAAGCAUUUAAGUGAUAGU +>cel-miR-1829a +CAACCAUUGGAAUUUCUCUAUU +>cel-miR-1829b +AAGCGAUCUUCUAGAUGGUUGUA +>cel-miR-1829c +AAGCGAAAUUCAAGAUGGUUGUA +>cel-miR-1830 +CGAGGUUUCACGUUUUCUAGGC +>cel-miR-1831 +ACCUGGCUGGGGGUAUCUCGUG +>cel-miR-1832 +UGGGCGGAGCGAAUCGAUGAU +>cel-miR-1833 +CGAGGCUUGCGAAAUAAGUGUGC +>cel-miR-1834 +AGAGAUCAACCAUUGAGAUCCAA diff --git a/modules/local/pita/templates/lib/RNAddG_compute.pl b/modules/local/pita/templates/lib/RNAddG_compute.pl new file mode 100755 index 00000000..451874d2 --- /dev/null +++ b/modules/local/pita/templates/lib/RNAddG_compute.pl @@ -0,0 +1,336 @@ +#!/usr/bin/perl + +use strict; +use List::Util qw[shuffle min max]; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/sequence_helpers.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/format_number.pl"; + +my $RNAHYBRID_EXE_DIR = "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/Bin/RNAHybrid/RNAhybrid-2.1/src"; +my $RNAddG_EXE_DIR = "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/"; + + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $ddG_area = get_arg("ddgarea", "70", \%args); +my $FULL_TL = get_arg("tl", "50", \%args); +my $DDG_OPEN = get_arg("dgtl", "25", \%args); +my $include_3max = get_arg("3max", 0, \%args); +my $include_ddG_v4 = get_arg("ddG_v4", 0, \%args); +my $components = get_arg("components", "", \%args); + +my $upstream_rest = get_arg("upstream_rest", 0, \%args); +my $downstream_rest = get_arg("downstream_rest", 0, \%args); +my $no_force = get_arg("noforce", 0, \%args); + +# Step over all Locations ########################################################### + +my $done = 0; +my $bunch_size = 1000; + +while (!$done) +{ + my @dGduplexesInputArray = (); + my @ddGInputArray = (); + my @headerInputArray = (); + my $record; + + for (my $nlines=0; $nlines < $bunch_size; $nlines++) + { + if (!($record = <$file_ref>)) + { + $done = 1; + last; + } + + chomp ($record); + my @row = split(/\t/, $record); + my $endpos = $row[2]; + my $miRNA = $row[8]; + my $utr = $row[11]; + my $force_binding_i =""; + my $force_binding_j =""; + + if (!$no_force) + { + # $force_binding = "-i $row[9] -j $row[10]"; + $force_binding_i = $row[9]; + $force_binding_j = $row[10]; + } + + # Calculate begining of target but make sure we're still in the UTR + + my $startpos = max ($endpos - $FULL_TL + 1, 1); + + my $maxtargetLen = $endpos - $startpos + 1; + my $target = substr ($utr, $startpos - 1, $maxtargetLen); + my $real_start = max ($endpos - $DDG_OPEN + 1, 1); + + push (@headerInputArray, join ("\t", splice(@row, 0, 8))); + push (@dGduplexesInputArray, join ("\t", $miRNA, $target, $force_binding_i, $force_binding_j)); + push (@ddGInputArray, join ("\t", $miRNA, $utr, $real_start, $endpos, $upstream_rest, $downstream_rest, $ddG_area)); + } + + my $arraySize = @headerInputArray; + + print STDERR "\nComputing $arraySize results: "; + + my @dGduplexesOutputArray = &getdGduplexes (@dGduplexesInputArray); + my @ddGOutputArray = &getddG (@ddGInputArray); + + for (my $i=0; $i < $arraySize; $i++) + { + my ($target_length, $dGall, $dG5, $dG3) = split (/\t/, $dGduplexesOutputArray[$i]); + my ($ddGall, $dG0, $dG1) = split (/\t/, $ddGOutputArray[$i]); + + $ddGall = $dGall + ($dG1 - $dG0); + + my $ddG_v4 = 0; + my $dG3max = 0; + my $dG3ratio = 0; + + print $headerInputArray[$i] . "\t$target_length\t$dGall\t$dG5\t$dG3\t$ddGall\t$dG0\t$dG1\t$ddG_v4\t$dG3max\t$dG3ratio\n"; + } +} + +print STDERR " Done.\n"; +# system ("rm tmp_seqfile1 tmp_seqfile2"); + + +################################################################################ + +sub getdGduplexes { + + my @inArray = @_; + my @outArray = (); + + open (SEQFILE, ">tmp_seqfile1") or die ("Could not open temporary sequence file.\n"); + + my $insize = @inArray; + + foreach my $oneTarget (@inArray) + { + (my $miRNA, my $target, my $force_binding_i, my $force_binding_j) = split (/\t/, $oneTarget); + print SEQFILE "$miRNA\n$target\n$force_binding_i\n$force_binding_j\n"; + } + + close (SEQFILE); + + + # Call RNAduplex and extract result dGs and length + + my $cmd = "$RNAddG_EXE_DIR/RNAduplex -5 0 < tmp_seqfile1"; + print STDERR "Calling RNAduplex with " . @inArray . " targets... "; + + my $result_of_cmd = `$cmd`; + + my @resArray = split (/\n/, $result_of_cmd); + + my $outsize = @resArray; + + if ($insize ne $outsize) + { + die "RNAduplex failure. Result was $result_of_cmd\n"; + } + + foreach my $resline (@resArray) + { + my ($ret_structure, $ret_start_miR, $ret_end_miR, $ret_start_target, $ret_end_target, $ret_miR_len, $ret_target_len, $ret_dGall, $ret_dG5, $ret_dG3) = split (/\t/, $resline); + push (@outArray, join ("\t", $ret_target_len, $ret_dGall, $ret_dG5, $ret_dG3)); + } + + return @outArray; +} + + +################################################################################ + +sub getddG { + + my @inArray = @_; + my @outArray = (); + my $upstream_rest; + my @seq_area; + + open (SEQFILE, ">tmp_seqfile2") or die ("Could not open temporary sequence file.\n"); + + foreach my $oneTarget (@inArray) + { + (my $miRNA, my $utr, my $startpos, my $endpos, $upstream_rest, my $downstream_rest, my $ddG_area) = split (/\t/, $oneTarget); + + # Extract area around sequence + @seq_area = &extract_sequence ($startpos, $endpos, $downstream_rest + $ddG_area, $upstream_rest + $ddG_area, $utr); + + print SEQFILE "$seq_area[2]\n"; + } + + close (SEQFILE); + + if ($upstream_rest != "0") + { + $upstream_rest =~ s/^0*//; # Because we're gonna call C with this argument and sscanf is problematic with leading zeros + } + + my $seq = $seq_area[2]; + my $bindStart = $seq_area[0]; + my $bindEnd = $seq_area[1]; + + my $target_len = $bindEnd - $bindStart + 1 + $downstream_rest; + + my $cmd = "$RNAddG_EXE_DIR/RNAddG4 -u $upstream_rest -s $bindEnd -f $target_len -t $target_len < tmp_seqfile2"; + + print STDERR "Calling RNAddG with " . @inArray . " targets... "; + + my @resArray = split (/\n/, `$cmd`); + + foreach my $resline (@resArray) + { + my @ddG_values = split (/\t/, $resline); + push (@outArray, join ("\t", $ddG_values[6], $ddG_values[3], $ddG_values[4])); + } + + return @outArray; +} + +################################################################################ + +sub extract_sequence { + + my $start_location = $_[0]; + my $end_location = $_[1]; + my $cur_us = $_[2]; + my $cur_ds = $_[3]; + my $sequence = $_[4]; + + #QQQ print STDERR "start = $start_location, end=$end_location; cur_us=$cur_us; cur_ds=$cur_ds\n"; + + my $us_start = $start_location > $cur_us ? $start_location - $cur_us : 1; + my $ds_end = $end_location + $cur_ds < length($sequence) ? $end_location + $cur_ds : length($sequence); + my $actual_start = $start_location - $us_start + 1; + + my $string = substr($sequence, $us_start - 1, ($ds_end - $us_start) + 1); + + my $actual_end = $actual_start + abs($end_location - $start_location); + + my @result = ($actual_start, $actual_end, $string); + + #QQQ print STDERR "string=$string length=" . length($string) . "\n"; + + return @result; +} + +# +# ################################################################################ +# +# sub getdG { +# +# print "getdG OBSOLETE. Please use getdGduplex.\n"; exit; +# +# my ($miRNA, $miR_start, $miR_len, $target, $target_start, $target_len) = @_ ; +# +# # Build miR and target substrings +# +# my $submiR = substr ($miRNA, $miR_start-1, $miR_len); +# my $subtarget = reverse (substr (reverse($target), $target_start-1, $target_len)); +# +# # Call RNAHybrid and extract result dG +# +# my $prog_line = "$RNAHYBRID_EXE_DIR/RNAhybrid -c -s 3utr_fly -b 1 $subtarget $submiR"; +# my @prog_result = split (/\n/, `$prog_line`); +# if (@prog_result != 1) +# { +# print STDERR "Cound not hybrid.\n"; +# print STDERR "Program call was: $prog_line\n"; +# print STDERR "Result was: " . join ("\n", @prog_result); +# exit; +# } +# +# +# #QQQ print STDERR "Program call was: $prog_line\n"; +# +# my @result = split (/:/, $prog_result[0]); +# my $dG = $result[4]; +# +# return $dG; +# } +# +# ################################################################################ +# +# sub getdGduplex { +# +# print "getdGduplex OBSOLETE. Please use getdGduplexes.\n"; exit; +# +# my ($miRNA, $miR_start, $miR_len, $target, $target_start, $target_len) = @_ ; +# +# # Build miR and target substrings +# +# my $submiR = substr ($miRNA, $miR_start-1, $miR_len); +# my $subtarget = reverse (substr (reverse($target), $target_start-1, $target_len)); +# +# # Call RNAduplex and extract result dG +# +# open (SEQFILE, ">tmp_seqfile1") or die ("Could not open temporary sequence file.\n"); +# print SEQFILE "$subtarget\n$submiR\n"; +# close (SEQFILE); +# +# print STDERR "\nCalling duplex with subtarget=$subtarget; submiR=$submiR\n"; +# +# my $resline = `$RNAddG_EXE_DIR/RNAduplex < tmp_seqfile1`; +# chomp ($resline); +# +# print STDERR "Result is: $resline\n"; +# +# $resline =~ m/ \((.*)\)/; +# return $1; +# } + + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/RNAddG_compute.pl + + Compute the dG energies of potential target sites whose seed is given in the external + tab file. + + Output consists of the input ID, followed by the following: + + Type miRNA coordinates Target coordinates + ==== ================= ================== + target_length + dG all nt 1 and up nt 1-FULL_TL + dG 5' nt 1-9 computed + dG 3' nt 10 and up computed + dG0 + dG1 + ddG_v4 + dG 3' max nt 10 and up Reverse complement of + miRNA bases 10 and up + dG 3' ratio + + -tl : Maximal target length (default: 50) + -dgtl : Target length when opening for ddG calculation (default: 25) + -ddgarea : Area upstream and downstream around target to fold (default: 70) + -no3max: Do not compute 3' max value and ratio (saves time) + -components : Print the components of the ddG calculation into the given file. + + + diff --git a/modules/local/pita/templates/lib/add_column.pl b/modules/local/pita/templates/lib/add_column.pl new file mode 100755 index 00000000..219cb933 --- /dev/null +++ b/modules/local/pita/templates/lib/add_column.pl @@ -0,0 +1,276 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/format_number.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/sequence_helpers.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $beginning = get_arg("b", 0, \%args); +my $column_location = get_arg("c", -1, \%args); +my $start_counter = get_arg("n", 0, \%args); +my $column_string = get_arg("s", "", \%args); +my $empty_string = get_arg("e", 0, \%args); +my $divide_columns_string = get_arg("d", "", \%args); +my $multiply_columns_string = get_arg("m", "", \%args); +my $subtract_columns_string = get_arg("u", "", \%args); +my $add_columns_string = get_arg("a", "", \%args); +my $min_columns_string = get_arg("min", "", \%args); +my $max_columns_string = get_arg("max", "", \%args); +my $count_columns_string = get_arg("count", "", \%args); +my $average_columns_string = get_arg("ave", "", \%args); +my $qauntile_range_string = get_arg("quant", "0,1", \%args); +my $concat_columns_string = get_arg("cat","", \%args); + +my $add_file = get_arg("f", "", \%args); +my $significant_nums = get_arg("sn", "2", \%args); + +$column_string =~ s/\"//g; + +my @divide_columns = split(/\,/, $divide_columns_string); +my @concat_columns = split(/\,/, $concat_columns_string); +my @multiply_columns = &ParseRanges($multiply_columns_string); +my @subtract_columns = split(/\,/, $subtract_columns_string); +my @add_columns = &ParseRanges($add_columns_string); +my @min_columns = &ParseRanges($min_columns_string); +my @max_columns = &ParseRanges($max_columns_string); +my @count_columns = &ParseRanges($count_columns_string); +my @average_columns = &ParseRanges($average_columns_string); +my @qauntile_range = split(/\,/, $qauntile_range_string); + +my @columns; +if (length($add_file) > 0) +{ + open(FILE, "<$add_file"); + while() + { + chomp; + + push(@columns, $_); + } +} + +my $row_counter = 0; +while (<$file_ref>) +{ + chomp; + + my $str = ""; + if (length($add_file) > 0) { $str = $columns[$row_counter]; } + elsif (length($column_string) > 0) { $str = $column_string; } + elsif ( $empty_string ) { $str = ""; } + elsif (length($divide_columns_string) > 0) + { + my @row = split(/\t/); + + $str = (length($row[$divide_columns[0]]) > 0 and length($row[$divide_columns[1]]) > 0 and $row[$divide_columns[1]] != 0) ? &format_number($row[$divide_columns[0]] / $row[$divide_columns[1]], $significant_nums) : ""; + } + elsif (length($concat_columns_string) > 0) +{ + my @row = split(/\t/); + $str=""; + for(my $k=0; $k < @concat_columns; $k++) + { + $str = $str . $row[$concat_columns[$k]]; + } +} + + elsif (length($multiply_columns_string) > 0) + { + my @row = split(/\t/); + $str = 1; + my $not_all_empty = 0; + for(my $k=0; $k < @multiply_columns; $k++) + { + if (length($row[$multiply_columns[$k]]) > 0) + { + $not_all_empty = 1; + $str = $str * $row[$multiply_columns[$k]]; + } + } + $str = ($not_all_empty == 1) ? &format_number($str, $significant_nums) : ""; + } + elsif (length($subtract_columns_string) > 0) + { + my @row = split(/\t/); + + $str = (length($row[$subtract_columns[0]]) > 0 and length($row[$subtract_columns[1]]) > 0) ? &format_number($row[$subtract_columns[0]] - $row[$subtract_columns[1]], $significant_nums) : ""; + } + elsif (length($add_columns_string) > 0) + { + my @row = split(/\t/); + $str = 0; + my $not_all_empty = 0; + for(my $k=0; $k < @add_columns; $k++) + { + if (length($add_columns[$k]) > 0) + { + $not_all_empty = 1; + $str = $str + $row[$add_columns[$k]]; + } + } + $str = ($not_all_empty == 1) ? &format_number($str, $significant_nums) : ""; + } + elsif (length($min_columns_string) > 0) + { + my @row = split(/\t/); + + $str = 100000000000000000; + my $not_all_empty = 0; + + for(my $k=0; $k < @min_columns; $k++) + { + if (length($row[$min_columns[$k]]) > 0) + { + $not_all_empty = 1; + $str = ($str < $row[$min_columns[$k]]) ? $str : $row[$min_columns[$k]]; + } + } + $str = ($not_all_empty == 1) ? &format_number($str, $significant_nums) : ""; + } + elsif (length($max_columns_string) > 0) + { + my @row = split(/\t/); + + $str = -100000000000000000; + my $not_all_empty = 0; + + for(my $k=0; $k < @max_columns; $k++) + { + if (length($row[$max_columns[$k]]) > 0) + { + $not_all_empty = 1; + $str = ($str > $row[$max_columns[$k]]) ? $str : $row[$max_columns[$k]]; + } + } + $str = ($not_all_empty == 1) ? &format_number($str, $significant_nums) : ""; + } + elsif (length($count_columns_string) > 0) + { + my @row = split(/\t/); + + $str = 0; + + for(my $k=0; $k < @count_columns; $k++) + { + if (length($row[$count_columns[$k]]) > 0) + { + $str = $str + 1; + } + } + } + elsif (length($average_columns_string) > 0) + { + my @row = split(/\t/); + + $str = ""; + my $not_all_empty = 0; + my @tmp_list = (); + + for(my $k=0; $k < @average_columns; $k++) + { + if (length($row[$average_columns[$k]]) > 0) + { + $not_all_empty = 1; + push(@tmp_list,$row[$average_columns[$k]]); + } + } + + if ($not_all_empty == 1) + { + if (($qauntile_range[0] > 0) or ($qauntile_range[1] < 1)) + { + @tmp_list = sort {$a <=> $b} @tmp_list; + } + my $first = int($qauntile_range[0] * @tmp_list); + $first = ($first < 0) ? 0 : $first; + my $last = int($qauntile_range[1] * @tmp_list); + $last = ($last > (@tmp_list - 1)) ? (@tmp_list - 1) : $last; + $first = ($first > $last) ? $last : $first; + + if (($last >= $first) and ($last < @tmp_list)) + { + $str = 0; + for (my $k = $first; $k <= $last; $k++) + { + $str = $str + $tmp_list[$k]; + } + $str = $str / ($last - $first +1); + } + } + $str = (($not_all_empty == 1) and (length($str) > 0)) ? &format_number($str, $significant_nums) : ""; + } + elsif ($start_counter == 1) { $str = $row_counter; } + + if ($column_location != -1) + { + my @row = split(/\t/); + + for (my $i = 0; $i < @row; $i++) + { + if ($i == $column_location) + { + if ($i == 0) { print "$str\t"; } + else { print "\t$str"; } + } + + if ($i > 0) { print "\t"; } + + print "$row[$i]"; + } + print "\n"; + } + elsif ($beginning == 1) { print "$str\t$_\n"; } + else { print "$_\t$str\n"; } + + $row_counter++; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/add_column.pl + + Adds a column to each of the lines of a file. + Operations on more than two columns can be specified using the ',-' notation (e.g., 1,4-6,23 means columns 1,4,5,6,23) + + -b: add the column as the first in the file (default: add at the end) + -c : add the column before column number + -e: add an empty column. + -n add a column counter, starting at num. + -s add a column with the specified string + -d add a column which is the value of column1 / column2 + -u add a column which is the value of column1 - column2 + -cat add a column which is the value of column1 . column2 . ... . columnk + -m add a column which is the value of column1 * column2 *..* columnk + -a add a column which is the value of column1 + column2 +..+ columnk + -min add a column which is the value of min(column1,column2,..,columnk) + -max add a column which is the value of max(column1,column2,..,columnk) + -count add a column which is the count of non empty entries over column1,column2,..,columnk. + -ave add a column which is the value of average(column1,column2,..,columnk) !! + -quant the quantile range of values on which to perform the operation (default: 0,1) + !! currently works only with -ave !! + e.g., to compute a trimmed mean in quantiles range 0.1 to 0.8 use: -ave c1,..,ck -quant 0.1,0.8 + -f : add the column from the specified file + -sn : The significant numbers to print (default: 2). + diff --git a/modules/local/pita/templates/lib/average_rows.pl b/modules/local/pita/templates/lib/average_rows.pl new file mode 100755 index 00000000..024d0fcb --- /dev/null +++ b/modules/local/pita/templates/lib/average_rows.pl @@ -0,0 +1,316 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/format_number.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libstats.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/vector_ops.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $source_key_str = get_arg("k", 0, \%args); +my $print_num_averaged_rows = get_arg("n", 0, \%args); +my $skip_num = get_arg("skip", 0, \%args); +my $min = get_arg("min", "", \%args); +my $max = get_arg("max", "", \%args); +my $take_max = get_arg("take_max", "", \%args); +my $take_min = get_arg("take_min", "", \%args); +my $take_true_med = get_arg("take_true_med", "", \%args); +my $take_sum = get_arg("take_sum", "", \%args); +my $take_last = get_arg("take_last", 0, \%args); +my $take_first = get_arg("take_first", -1, \%args); +my $precision = get_arg("precision", 3, \%args); +my $std = get_arg("std", "", \%args); +my $losoe = get_arg("losoe", "", \%args); +my $list = get_arg("list", "", \%args); +my $size = get_arg("size", 0, \%args); +my $delim = get_arg("delim", "\t", \%args); +my $weights_col = get_arg("w", -1, \%args); + + +my @source_key = split(/\,/, $source_key_str); +my %source_key_hash; +foreach my $key (@source_key) +{ + $source_key_hash{$key} = "1"; +} + +my %key2id; +my %occurences_by_id; +my $key_counter = 0; +my @averaged_data; +my @averaged_counts; +my @row_counts; +my $max_columns = 0; + +for (my $i = 0; $i < $skip_num; $i++) { my $line = <$file_ref>; print "$line"; } + +while(<$file_ref>) +{ + chomp; + + my @row = split(/\t/); + + if (@row > $max_columns) { $max_columns = @row; } + + my $key = &GetKey(\@row); + my $id = $key2id{$key}; + if (length($id) == 0) + { + $id = $key_counter++; + $key2id{$key} = $id; + #$averaged_data[$id][0] = $key; + } + + if ($take_first != -1) + { + my $occurences = $occurences_by_id{$id}; + + if (length($occurences) == 0 or $occurences < $take_first) + { + print "$_\n"; + + $occurences_by_id{$id} = $occurences + 1; + } + } + else + { + for (my $i = 0; $i < @row; $i++) + { + if (length($row[$i]) > 0 and length($source_key_hash{$i}) == 0) + { + if (length($min) > 0 and $row[$i] < $min) { $row[$i] = $min; } + if (length($max) > 0 and $row[$i] > $max) { $row[$i] = $max; } + + if ($take_max == 1) + { + if (length($averaged_data[$id][$i]) == 0 or $averaged_data[$id][$i] < $row[$i]) + { + $averaged_data[$id][$i] = $row[$i]; + } + } + elsif ($take_min == 1) + { + if (length($averaged_data[$id][$i]) == 0 or $averaged_data[$id][$i] > $row[$i]) + { + $averaged_data[$id][$i] = $row[$i]; + } + } + elsif ($take_last == 1) + { + $averaged_data[$id][$i] = $row[$i]; + } + elsif ($take_sum == 1) + { + if (length($averaged_data[$id][$i]) == 0) + { + $averaged_data[$id][$i] = $row[$i]; + } + else + { + $averaged_data[$id][$i] += $row[$i]; + } + } + elsif ($losoe == 1) + { + if (length($averaged_counts[$id][$i]) == 0) + { + $averaged_counts[$id][$i] = 0; + } + $averaged_data[$id][$i][$averaged_counts[$id][$i]] = $row[$i]; + + } + elsif ($std == 1) + { + if (length($averaged_counts[$id][$i]) == 0) + { + $averaged_counts[$id][$i] = 0; + } + $averaged_data[$id][$i][$averaged_counts[$id][$i]] = $row[$i]; + } + elsif ($list == 1) + { + if (length($averaged_counts[$id][$i]) == 0) + { + $averaged_counts[$id][$i] = 0; + } + $averaged_data[$id][$i][$averaged_counts[$id][$i]] = $row[$i]; + + } + elsif ($take_true_med == 1) + { + if (length($averaged_counts[$id][$i]) == 0) + { + $averaged_counts[$id][$i] = 0; + } + $averaged_data[$id][$i][$averaged_counts[$id][$i]] = $row[$i]; + } + elsif ($weights_col > -1){ + $averaged_data[$id][$i] += $row[$i]*$row[$weights_col]; + } + else + { + $averaged_data[$id][$i] += $row[$i]; + } + + if($weights_col > -1){ + $averaged_counts[$id][$i]+=$row[$weights_col] ; + } + else{ + $averaged_counts[$id][$i]++; + } + $row_counts[$id][$i]++; + } + elsif (length($source_key_hash{$i}) > 0) + { + $averaged_data[$id][$i] = $row[$i]; + } + } + } +} + +if ($take_first == -1) +{ + for (my $i = 0; $i < $key_counter; $i++) + { + if ($print_num_averaged_rows == 1) + { + my $max = 0; + for (my $j = 1; $j < $max_columns; $j++) + { + if (length($row_counts[$i][$j]) > 0 and $row_counts[$i][$j] > $max) + { + $max = $row_counts[$i][$j]; + } + } + print "$max\t"; + } + + #print "$averaged_data[$i][0]\t"; + + for (my $j = 0; $j < $max_columns; $j++) + { + if ($j > 0) { print "\t"; } + + if (length($source_key_hash{$j}) == 0) + { + if ($take_max == 1) + { + print &format_number($averaged_data[$i][$j], $precision); + } + elsif ($take_min == 1) + { + print &format_number($averaged_data[$i][$j], $precision); + } + elsif ($take_sum == 1) + { + print &format_number($averaged_data[$i][$j], $precision); + } + elsif ($take_last == 1) + { + print $averaged_data[$i][$j]; + } + elsif ($losoe == 1) + { + #for(my $k=0; $k<$averaged_counts[$i][$j]; $k++) + #{ + #print $averaged_data[$i][$j][$k].", "; + #} + print LogOfSumOfExps($averaged_data[$i][$j]); + } + elsif ($std == 1) + { + print &format_number(&vec_std($averaged_data[$i][$j]), $precision); + } + elsif ($list == 1) + { + my @arr = @{$averaged_data[$i][$j]}; + if ( ($size == 0) || ($size > length (@arr)) ) + { + print join($delim, @arr); + } + else + { + print join($delim, @arr[0..($size-1)]); + } + } + elsif ($take_true_med == 1) + { + print &format_number(&vec_true_median($averaged_data[$i][$j]), $precision); + } + elsif (length($averaged_counts[$i][$j]) > 0 and $averaged_counts[$i][$j]>0) + { + print &format_number($averaged_data[$i][$j] / $averaged_counts[$i][$j], $precision); + } + + } + else + { + print $averaged_data[$i][$j]; + } + } + + print "\n"; + } +} + +sub GetKey (\@) +{ + my ($row_str) = @_; + + my @row = @{$row_str}; + + my $res = $row[$source_key[0]]; + + for (my $i = 1; $i < @source_key; $i++) + { + $res .= "\t$row[$source_key[$i]]"; + } + + return $res; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/average_rows.pl + + Average rows in that have the same key + + -k : Column of the key (default is 0) + NOTE: an index of multiple keys may be specified with commas (e.g., -k 1,4,5) + -n: Add the number of rows that went into the averaging + -skip : Skip num rows in the source file and just print them (default: 0) + -min : Values below num are converted to num + -max : Values above num are converted to num + -precision : Precision of the numbers printed (default: 3 digits) + -take_max: Instead of taking average for same key, take max + -take_min: Instead of taking average for same key, take min + -take_sum: Instead of taking average for same key, take sum of values + -take_true_med: Instead of taking average for same key, take the true median (if number of items is even, average two middle ones) + -take_last: Instead of taking average for same key, take last occurence + -take_first : Instead of taking average for same key, take first occurences + -losoe: calculate Log Of Sum Of Exps for every key + -std: calculate standard deviation for every key + -list: outputs for each key the list of values (comma seperated) + -size : if -list is used, print only the first on the list (default: print all) + -delim : if -list is used, print the list using as delimiter (default is tab) + -w : calculate weighted average using column as weights diff --git a/modules/local/pita/templates/lib/body.pl b/modules/local/pita/templates/lib/body.pl new file mode 100755 index 00000000..dcdc494a --- /dev/null +++ b/modules/local/pita/templates/lib/body.pl @@ -0,0 +1,155 @@ +#!/usr/bin/perl + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; + +use strict; + +my $beg = undef; +my $end = undef; +my $count_blanks = 1; +my $quiet = 0; +my @skip_lines; +my @select_lines; +my $fin = \*STDIN; +my $fraction=0; +while(@ARGV) +{ + my $arg = shift @ARGV; + if($arg eq '--help') + { + print STDOUT ; + exit(0); + } + elsif($arg eq '-f') + { + $fraction = 1; + } + elsif($arg eq '-b') + { + $count_blanks = 0; + } + elsif(not(defined($beg))) + { + $beg = $fraction?$arg:int($arg); + } + elsif(not(defined($end))) + { + $end = $fraction?$arg:int($arg); + } + elsif($arg eq '-skip') + { + my $lines_str = shift @ARGV; + @skip_lines = sort {$a <=> $b} parseRanges($lines_str); + } + elsif($arg eq '-select') + { + my $lines_str = shift @ARGV; + @select_lines = sort {$a <=> $b} parseRanges($lines_str); + } + elsif($arg eq '-quiet') + { + $quiet = 1; + } + elsif(-f $arg or -l $arg) + { + open($fin, $arg) or die("Could not open file '$arg'"); + } + else + { + die("/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/body.pl: Bad argument '$arg' given. Use --help for help."); + } +} + +if(not(defined($beg))) +{ + $beg = 1; +} + +if(not(defined($end))) +{ + $end = -1; +} + +my $num_lines = undef; +my $tmp_file = undef; +if($end < -1 or ($beg<1 and $beg>0) or ($end>-1 and $end<0) or ($end<1 and $end>0)) +{ + $tmp_file = 'tmp_' . time . '.' . rand() . './nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/body.pl'; + open(TMP, ">$tmp_file") or die("Could not open temporary file '$tmp_file' for writing"); + while(<$fin>) + { print TMP; } + close(TMP); + + my $wc = `wc -l $tmp_file`; + my @tuple = split(/\s+/,$wc); + $num_lines = $tuple[0]; + print STDERR "The file has $num_lines number of lines.\n" unless ( $quiet ); + + open($fin, "<$tmp_file") or die("Could not open the temporary file '$tmp_file' for reading"); + +} + +my $line = 0; +my $skip_counter = 0; +my $select_counter = 0; +if(defined($num_lines)){ + if ($end<-1){ + $end=$num_lines + $end + 1; + } + if (($end>-1 and $end<0)){ + $end = $num_lines + sprintf("%.f",$end*$num_lines); + } + if (($end<1 and $end>0)){ + $end = sprintf("%.f",$end*$num_lines); + } + if ($beg<1 and $beg>0){ + $beg = sprintf("%.f",$beg*$num_lines) + 1; + } +} +while(<$fin>) +{ + if($count_blanks or /\S/) + { + $line++; + if (@skip_lines >= $skip_counter and $line == $skip_lines[$skip_counter]) + { + $skip_counter++; + next; + } + if (@select_lines>0 and $line != $select_lines[$select_counter]) + { + next; + } + $select_counter++; + + + if($line >= $beg and ($end == -1 or $line <= $end)) + { + print; + } + } +} + +if(defined($tmp_file)) +{ + system("rm -f $tmp_file"); +} + +exit(0); + +__DATA__ +Syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/body.pl BEG END < FILE + +BEG, END are the beginning and end lines (inclusive) to select from +the file. If END=-1 then the rest of the file is included for example BEG=2 END=-1 +returns the whole file except the first row. + +OPTIONS are: + +-b: Do *not* include blank lines when counting (default counts them). +-skip : Exclude line numbers n1,n2... +-select : Select line numbers n1,n2... +-quiet: Do not print any message to STDERR. +-f: Allow giving BEG and END as fractions of number of lines in file (for example /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/body.pl 4 -0.2) + + diff --git a/modules/local/pita/templates/lib/cap.pl b/modules/local/pita/templates/lib/cap.pl new file mode 100755 index 00000000..3abef361 --- /dev/null +++ b/modules/local/pita/templates/lib/cap.pl @@ -0,0 +1,86 @@ +#!/usr/bin/perl + +use strict; + +if($#ARGV==-1) +{ + print STDERR ; + exit(1); +} + +my $file = \*STDIN; +my $header = ''; +my $serial; +my @header; +while(@ARGV) +{ + my $arg = shift @ARGV; + if($arg eq '--help') + { + print STDOUT ; + exit(0); + } + elsif($arg eq '-f') + { + $arg = shift @ARGV; + (-f $arg) or die("Could not open header file '$arg'."); + $header = `cat $arg`; + chomp($header); + @header = split("\t",$header); + } + elsif($arg eq '-n') + { + $serial = 1; + } + elsif(-f $arg) + { + open($file,$arg) or die("Could not open file '$arg' for reading."); + } + else + { + $header .= (length($header)>0 ? " " : "") . $arg; + @header = split(',',$header); + } +} + +# Parse the list +if ($serial == 1) +{ + my $line = <$file>; + my @r=split(/\t/, $line); + for (my $i = 0; $i <= $#r; $i++) + { + if ($i > 0) + { + print "\t".($i+1); + } + else + { + print ($i+1); + } + } + print "\n$line"; +} +else +{ + print join("\t", @header), "\n"; +} + +while(<$file>) +{ + print; +} + +__DATA__ +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cap.pl [OPTIONS] COMMA-SEPERATED-LIST FILE + +TAB_FILE - a tab-delimited file (can also be passed into standard input. + +Sticks a header line onto the file. The comma-seperated list gives +a field name for the first columns in FILE. + +OPTIONS are: + +-f FILE: read the header from FILE. In this case, no comma-seperated list is expected. + +-n : print serial headers (1,2,3....) diff --git a/modules/local/pita/templates/lib/cut.pl b/modules/local/pita/templates/lib/cut.pl new file mode 100755 index 00000000..07b9a534 --- /dev/null +++ b/modules/local/pita/templates/lib/cut.pl @@ -0,0 +1,227 @@ +#!/usr/bin/perl + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; + + +use strict; + +my @cols; +my $col; +my $col_max=10000; +my @append_cols; +my @prepend_cols; + + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); +my $verbose = get_arg("q", 0, \%args); +if ($verbose) {$verbose=0} else {$verbose=1} +my $skip_col= get_arg("sk",0, \%args); +my $headers= get_arg("h", 0, \%args); +my $delim_in= get_arg("d", "\t", \%args); +my $delim_out=$delim_in; +if (get_arg("di", "", \%args)) {$delim_in= get_arg("di", "\t", \%args)} +if (get_arg("do", "", \%args)) {$delim_out= get_arg("do", "\t", \%args)} +my $col_ranges= get_arg("f", "1", \%args); +my $multiple_delim_ins= get_arg("m", 0, \%args); +my $suppress_blanks= get_arg("s", 0, \%args); +my $tight= get_arg("t", 0, \%args); +my $invert= get_arg("i", 0, \%args); +my $get_cols_by_header=get_arg("n","",\%args); +my $zerobased= get_arg("0", 0, \%args); +my $preserve_empty_values = get_arg("e", 0, \%args); +my $name_file = get_arg("file", "", \%args); +my $line=0; + +# print STDERR join(",",@cols), "\n"; +# @cols = (@prepend_cols, @cols, @append_cols); + +if ($name_file ne ""){ + open (NFILE,$name_file); + my @n; + while(){ + chomp; + push @n,$_; + } + close NFILE; + $get_cols_by_header=join(",",@n); +} + +my $first_line=""; +if ($get_cols_by_header ne ""){ + $first_line=<$file_ref>; + my $l=$first_line; + chomp $l; + my @header=split /\t/,$l,-1; + my %heads; + for (my $i=0;$i0){ $col_ranges="1-$skip_col,".$col_ranges } + +@cols = &parseRanges($col_ranges); + + +my $data_line=0; +my @tuple; +my @tuple_all; +my $value; +my $beg; +my $end; +my $fixed_cols=0; +my $cols_ref; +my $max_cols = 0; +while($first_line ne "" or $_=<$file_ref>) +{ + if ($first_line ne ""){ + $_=$first_line; + $first_line=""; + } + + $line++; + + if ($headers >= $line) + { + print; + } + else + { + if(defined($col_ranges)) + { + my $num_cols = &numTokens($delim_in); + if($num_cols > $max_cols or ($tight and $num_cols != $max_cols)) + { + $max_cols = $num_cols; + @cols = &parseRanges($col_ranges, $max_cols); + # print STDERR join(',',@cols), "\n"; + if (!$zerobased){ + for(my $i = 0; $i < scalar(@cols); $i++) + { + $cols[$i]--; + } + } + } + } + + if(/\S/ and not(/^\s*#/)) + { + if($multiple_delim_ins) + { + @tuple_all = split(/[$delim_in]+/,$_,-1); + } + else + { + @tuple_all = split($delim_in,$_,-1); + } + if($#tuple_all >= 0) + { chomp($tuple_all[$#tuple_all]); } + + @tuple=(); + + if (not $invert) + { + foreach my $i (@cols) + { + if($preserve_empty_values or $i <= $#tuple_all) + { + push(@tuple,$tuple_all[$i]); + } + } + } + else + { + my %cols_hash; + for my $i (@cols) + { + $cols_hash{$i}=1; + } + for my $i (0..$#tuple_all) + { + if($i <= $#tuple_all and not $cols_hash{$i}) + { + push(@tuple,$tuple_all[$i]); + } + } + } + + my $result = join($delim_out,@tuple); + + if(not($suppress_blanks) or $result =~ /\S/) + { + print $result, "\n"; + } + } + elsif(not($suppress_blanks) or /\S/) + { + print; + } + } +} + +exit(0); + +__DATA__ + +syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cut.pl [OPTIONS] TAB_FILE + +TAB_FILE is any tab-delim_inited file. Can also be passed into standard + input. + +OPTIONS are: + +-q: Quiet mode: turn verbosity off (default verbose) +-h NUM: Set the number of row headers to NUM (default 0). +-d DELIM: Change the input and output delimiter to DELIM (default ). +-di DELIM: Change the input delimiter to DELIM (default ). +-do DELIM: Change the output delimiter to DELIM (default ). +-s: Suppress blanks +-i: Invert. Use the complement of the fields specified in -f. +-t: Tight. Tell the script to expect different number of columns in + each row so that it needs to recompute the column boundaries for + each row. Note this option slows the script down somewhat. +-f RANGES: specify column ranges to include. RANGES are comma- + seperated lists of single columns or a range of columns + for example: + + 5-6,2,1-3 + + would select columns 1 through 6 except column 4. Note + that 2 is redundantly specified by no error results. +-n : specify columns by names (instead of by numbers with -f). Assumes + the first line is a header, and translates column names in + into their respective column numbers in the header. Supports + multiple ranges. Column names are assumed to be unique and not to + contain any commas. +-file : get column names (as in -n) from specified file. each column name + should appear on a separate line. +-0: zero-based column numbers. +-e: preserve empty values. +-sk: number of header columns (default 0) + diff --git a/modules/local/pita/templates/lib/dos2unix.pl b/modules/local/pita/templates/lib/dos2unix.pl new file mode 100755 index 00000000..074b078b --- /dev/null +++ b/modules/local/pita/templates/lib/dos2unix.pl @@ -0,0 +1,56 @@ +#!/usr/bin/perl + +use strict; + +my $arg; +my $verbose=1; + +while(@ARGV) +{ + $arg = shift @ARGV; + + if($arg eq '--help') + { + &printSyntax(); + exit(0); + } + elsif($arg eq '-q') + { + $verbose = 0; + } + else + { + &printSyntax(); + exit(1); + } +} + +if(not(-T STDIN)) +{ + if($verbose) + { + print STDERR "File is not a text file, skipping.\n"; + } + exit(1); +} + +while() +{ + s/ //g; + print; +} + +exit(0); + +sub printSyntax +{ + print STDERR "Syntax: $0 [OPTIONS] < FILE\n", + "\n", + "where FILE is any text file", + "\n", + "where OPTIONS are\n", + "\n", + "-q: Quiet mode (default is verbose)\n", + "\n"; +} + diff --git a/modules/local/pita/templates/lib/extract_sequence.pl b/modules/local/pita/templates/lib/extract_sequence.pl new file mode 100755 index 00000000..592f264b --- /dev/null +++ b/modules/local/pita/templates/lib/extract_sequence.pl @@ -0,0 +1,180 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/sequence_helpers.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $key_name = get_arg("k", "EXTRACT_ALL_KEYS", \%args); +my $start_location = get_arg("s", 1, \%args); +my $end_location = get_arg("e", -1, \%args); +my $cur_strand = get_arg("st", "", \%args); +my $locations_file = get_arg("f", "", \%args); +my $print_location_description = get_arg("d", 0, \%args); +my $print_location_name = get_arg("dn", 0, \%args); +my $print_location_description_chr = get_arg("dc", 0, \%args); +my $zero_based_coordinates = get_arg("0", 0, \%args); +my $gap = get_arg("g", 1, \%args); +my $minplus = get_arg("mp", 0, \%args); + +if ($cur_strand ne "") { $minplus = 1; } + +if ($gap<1) { $gap=1 } + +my $subtraction_coordinates = $zero_based_coordinates == 1 ? 0 : 1; + +my %key_starts; +my %key_ends; +my %key_strands; +my %key_output_names; +if (length($locations_file) > 0) +{ + open(LOCATIONS, "<$locations_file"); + while() + { + chop; + + my @row = split(/\t/); + + $key_starts{$row[0]} .= "$row[2]\t"; + $key_ends{$row[0]} .= "$row[3]\t"; + $key_output_names{$row[0]} .= "$row[1]\t"; + if ($minplus) + { + $key_strands{$row[0]} .= "$row[4]\t"; + } + + #print STDERR "key_starts{$row[0]}=$key_starts{$row[0]}\n"; + #print STDERR "key_ends{$row[0]}=$key_ends{$row[0]}\n"; + #print STDERR "key_output_names{$row[0]}=$key_output_names{$row[0]}\n"; + } +} +else +{ + $key_starts{$key_name} = $start_location; + $key_ends{$key_name} = $end_location; + $key_strands{$key_name} = $cur_strand; + $key_output_names{$key_name} = $key_name; +} + +while(<$file_ref>) +{ + chop; + + my @row = split(/\t/); + + if ((length($locations_file) == 0 and $key_name eq "EXTRACT_ALL_KEYS") or length($key_starts{$row[0]}) > 0) + { + my $key = length($key_starts{$row[0]}) > 0 ? $row[0] : "EXTRACT_ALL_KEYS"; + my @starts = split(/\t/, $key_starts{$key}); + my @ends = split(/\t/, $key_ends{$key}); + my @strands = split(/\t/, $key_strands{$key}); + my @output_names = split(/\t/, $key_output_names{$key}); + + for (my $i = 0; $i < @starts; $i++) + { + my $start_location = $starts[$i]; + my $end_location = $ends[$i]; + my $strand = $strands[$i]; + + my $output_name = length($output_names[$i]) > 0 ? $output_names[$i] : $row[0]; + + if ($print_location_description == 1) + { + + print "$output_name from $start_location to $end_location\t"; + } + elsif ($print_location_name == 1) + { + print "$output_name\t"; + } + elsif ($print_location_description_chr == 1){ + print "$row[0]\t$output_name\t$start_location\t$end_location\t"; + } + else + { + print "$row[0]\t"; + } + + if ($start_location == 0 and $zero_based_coordinates != 1) { $end_location = length($row[1]); } + if ($end_location == -1) { $end_location = length($row[1]); } + + my $sequence_start = $start_location < $end_location ? $start_location : $end_location; + + my $string = substr($row[1], $sequence_start - $subtraction_coordinates, abs($end_location - $start_location) + 1); + + if ($gap>1) { + my $new_string; + for (my $j=0;$j $end_location) + { + $string = &ReverseComplement($string); + } + } + print "$string\n"; + } + } +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/extract_sequence.pl + + Extracts a sequence from a given stab file + + NOTE: Locations here are specified in 1-based coordinates (change with -0) + + -0: Zero-based coordinates (default: 1-based coordinates) + + -k : Key to extract (default: extract from all keys) + -s : Start location (default: 1) + -e : End location (default: end of sequence) + -st : Strand ('"+"' or '"-"') to force, otherwise determined by start>end. + + -f : File containing the locations to extract in the format: + keynamestartend + + -mp: Take the fifth column of the input location files as the strand (+ or -) + and disregard the ordering of start, end. Good especially when extracting + a sequence of length 1 (strand is anbigous when start=end). + + -d: Print the full description of the location of the extracted sequence + -dn: Print only the name of the extracted sequence + -dc: Print description in chr format + + -g : Extract only every nth letter (default: 1). + diff --git a/modules/local/pita/templates/lib/fasta2stab.pl b/modules/local/pita/templates/lib/fasta2stab.pl new file mode 100755 index 00000000..e19c13e4 --- /dev/null +++ b/modules/local/pita/templates/lib/fasta2stab.pl @@ -0,0 +1,86 @@ +#!/usr/bin/perl + +use strict; +my $arg; + +my $fin = \*STDIN; +my $line_to_extract = -1; +my $ignore_N = 0; +while(@ARGV) +{ + $arg = shift @ARGV; + + if ($arg eq '--help') + { + print STDOUT ; + exit(0); + } + elsif (-f $arg) + { + open($fin,$arg) or die("Can't open file '$arg' for reading."); + } + elsif($arg eq '-l') + { + $line_to_extract = shift @ARGV; + } + elsif ($arg eq '-ignore_N') + { + $ignore_N = 1; + } + else + { + die("Bad argument '$arg' given."); + } +} + +my $name = ""; +my $seq = ""; +my $line; +while(<$fin>) +{ + chomp; + if(/\S/) + { + if(/^[ ]*>/) + { + $line = 0; + s/^[ ]*>[ ]*//; + if (length($name) > 0 and length($seq) > 0) + { + $seq = uc ($seq); + if ($ignore_N == 0 or index($seq, "N") == -1) + { + print "$name\t$seq\n"; + } + } + $name = $_; + $seq = ""; + } + else + { + $line++; + + if ($line_to_extract == -1 or $line == $line_to_extract) + { + s/[ ]//g; + $seq .= $_; + } + } + } +} + +if (length($seq) > 0) +{ + $seq = uc ($seq); + print "$name\t$seq\n"; +} + +__DATA__ + +syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/fasta2stab.pl [OPTIONS] < FASTA + + -l : Extract only line of the fasta from each sequence + (useful for parsing alignments given in fasta) + + -ignore_N: Do not print sequences that contain N. + diff --git a/modules/local/pita/templates/lib/find_potential_mirna_targets.pl b/modules/local/pita/templates/lib/find_potential_mirna_targets.pl new file mode 100755 index 00000000..25ae8f12 --- /dev/null +++ b/modules/local/pita/templates/lib/find_potential_mirna_targets.pl @@ -0,0 +1,389 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/sequence_helpers.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $microrna_file = get_arg("f", "", \%args); +my $lengths_str = get_arg("l", "6-8", \%args); +my $gu_wobble_str = get_arg("gu", "6;0,7;1,8;1", \%args); +my $mismatches_str = get_arg("m", "6;0,7;0,8;1", \%args); +my $loops_str = get_arg("loop", "", \%args); +my $microrna_start_pairing = get_arg("mb", 2, \%args); +my $min_target_length = get_arg("min_len", 22, \%args); +my $output_random_locations = get_arg("random", 0, \%args); +my $plm = get_arg("plm", 0, \%args); + + +my @lengths; +if ($lengths_str =~ /[\-]/) +{ + @lengths = split(/\-/, $lengths_str); +} +else +{ + $lengths[0] = $lengths_str; + $lengths[1] = $lengths_str; +} +my @allowed_lengths; +for (my $i = $lengths[0]; $i <= $lengths[1]; $i++) +{ + push(@allowed_lengths, $i); +} +my $num_allowed_lengths = @allowed_lengths; +print STDERR "allowed lengths = @allowed_lengths\n"; + +my %allowed_gu_wobbles; +my @gu_wobble = split(/\,/, $gu_wobble_str); +for (my $i = 0; $i < @gu_wobble; $i++) +{ + my @row = split(/\;/, $gu_wobble[$i]); + $allowed_gu_wobbles{$row[0]} = $row[1]; + + print STDERR "allowed_gu_wobbles{$row[0]} = $allowed_gu_wobbles{$row[0]}\n"; +} + +my %allowed_mismatches; +my @mismatches = split(/\,/, $mismatches_str); +for (my $i = 0; $i < @mismatches; $i++) +{ + my @row = split(/\;/, $mismatches[$i]); + $allowed_mismatches{$row[0]} = $row[1]; + + print STDERR "allowed_mismatches{$row[0]} = $allowed_mismatches{$row[0]}\n"; +} + +my @allowed_loops; +my @loops = split(/\,/, $loops_str); +for (my $i = 0; $i < @loops; $i++) +{ + push(@allowed_loops, $loops[$i]); +} +print STDERR "allowed_loops = @allowed_loops\n"; + +my @microrna_names; +my @microrna_sequences; +open(INPUT_FILE, "<$microrna_file"); +while() +{ + chop; + + my @row = split(/\t/); + + push(@microrna_names, $row[0]); + $row[1] =~ s/U/T/g; + push(@microrna_sequences, $row[1]); +} +print STDERR "MicroRNA Names: @microrna_names\n"; +print STDERR "MicroRNA Sequences: @microrna_sequences\n"; + +my $curr_row_num = 0; + +while(<$file_ref>) +{ + chop; + + my @row = split(/\t/); + + $row[1] =~ s/U/T/g; + my $rc_sequence = &ReverseComplement($row[1]); + my $sequence_length = length($rc_sequence); + + #print STDERR "$row[1] --> \n"; + #print STDERR "$rc_sequence\n\n"; + + $curr_row_num++; + print STDERR $curr_row_num."\n"; + + if ($output_random_locations == 0) + { + for (my $i = $microrna_start_pairing - 1; $i <= length($rc_sequence) - $min_target_length; $i++) + { + #print STDERR "i = $i\n"; + + my $subsequence = substr($rc_sequence, $i, $allowed_lengths[$num_allowed_lengths - 1]); + + for (my $j = 0; $j < @microrna_sequences; $j++) + { + my @target = &IsPotentialTarget($subsequence, $microrna_sequences[$j]); + if ($target[0] > 0) + { + for (my $k = 0; $k < @target; $k += 7) + { + my $rc_start = ($i - ($microrna_start_pairing - 1)); + my $rc_length = $target[$k] + ($microrna_start_pairing - 1); + my $start = $sequence_length - 1 - $rc_start; + my $end = $sequence_length - 1 - ($rc_start + $rc_length - 1); + $start++; # 1-based coordinate correction + $end++; # 1-based coordinate correction + my $subsequence = substr($rc_sequence, $rc_start, $rc_length); + print "$microrna_names[$j]\t"; + print "$row[0]\t"; + print "$start\t"; + print "$end\t"; + print "$target[$k]\t"; + print $target[$k + 1] . "\t"; + print $target[$k + 2] . "\t"; + print ( ($target[$k + 3] + $target[$k + 4]) > 0 ? "1" : "0" ); + print "\t$microrna_sequences[$j]\t"; + print "$subsequence\t"; + print $target[$k + 6] . "\t"; + print $target[$k + 5] . "\n"; + } + } + } + } + } + else + { + my $random_length = length($rc_sequence) - $min_target_length; + if ($random_length >= 0) + { + my $sequence_position = int(rand($random_length + 1)); + + my $subsequence = substr($rc_sequence, $sequence_position, $allowed_lengths[$num_allowed_lengths - 1]); + + for (my $j = 0; $j < @microrna_sequences; $j++) + { + my $start = $sequence_length - 1 - $sequence_position + 1; + my $end = $sequence_length - 1 - ($sequence_position + $allowed_lengths[$num_allowed_lengths - 1] - 1) + 1; + my $length = $allowed_lengths[$num_allowed_lengths - 1]; + + print "$microrna_names[$j]\t$row[0]\t$start\t$end\t$length\t0\t0\t0\t$microrna_sequences[$j]\t$subsequence\t0\t0\n"; + } + } + } +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub IsPotentialTarget +{ + my ($subsequence, $microrna_sequence) = @_; + + my @res; + + # print STDERR " Subseq:$subsequence MicroRNA:$microrna_sequence\n"; + + for (my $i = $allowed_lengths[$num_allowed_lengths - 1]; $i >= $allowed_lengths[0]; $i--) + { + my $subseq = substr($subsequence, 0, $i); + if (length($subseq) == $i) + { + my @comparison_stats = &AlignSequenceOntoSequence($subseq, $microrna_sequence, $microrna_start_pairing - 1); + my $mismatches = $comparison_stats[0] - $comparison_stats[1]; + my $gu_wobbles = $comparison_stats[1]; + + my $last_pos = $comparison_stats[2]; + if (($i == $allowed_lengths[0]) or ($last_pos == 0) or ($plm == 1)) + { + + if (($mismatches <= $allowed_mismatches{$i}) and ($gu_wobbles <= $allowed_gu_wobbles{$i})) + { + push(@res, $i); + push(@res, $mismatches); + push(@res, $gu_wobbles); + push(@res, 0); + push(@res, 0); + + my @pairings = &FindPairings($subseq, $microrna_sequence, $microrna_start_pairing - 1, -1, -1); + push(@res, $pairings[0]); + push(@res, $pairings[1]); + + last; + } + } + } + } + + for (my $i = 0; $i < @allowed_loops; $i++) + { + my $seq_length = $allowed_loops[$i]; + for (my $j = 1; $j < $seq_length - 1; $j++) + { + my $subseq = substr($subsequence, 0, $j) . substr($subsequence, $j + 1, $seq_length - ($j + 1)); + if (length($subseq) == $seq_length - 1) + { + my @comparison_stats = &AlignSequenceOntoSequence($subseq, $microrna_sequence, $microrna_start_pairing - 1); + my $mismatches = $comparison_stats[0] - $comparison_stats[1]; + my $gu_wobbles = $comparison_stats[1]; + + if (($mismatches <= $allowed_mismatches{$seq_length}) and ($gu_wobbles <= $allowed_gu_wobbles{$seq_length})) + { + push(@res, $seq_length); + push(@res, $mismatches); + push(@res, $gu_wobbles); + push(@res, 0); + push(@res, 1); + + my @pairings = &FindPairings(substr($subsequence, 0, $seq_length), $microrna_sequence, $microrna_start_pairing - 1, $j, -1); + push(@res, $pairings[0]); + push(@res, $pairings[1]); + + #print STDERR "Found loop in target at bp " . ($j + 1) . "\n"; + } + } + + my $subseq = substr($subsequence, 0, $seq_length); + if (length($subseq) == $seq_length) + { + my $microrna_subseq = substr($microrna_sequence, 0, $j + $microrna_start_pairing - 1); + $microrna_subseq .= substr($microrna_sequence, $j + $microrna_start_pairing); + my @comparison_stats = &AlignSequenceOntoSequence($subseq, $microrna_subseq, $microrna_start_pairing - 1); + my $mismatches = $comparison_stats[0] - $comparison_stats[1]; + my $gu_wobbles = $comparison_stats[1]; + + if (($mismatches <= $allowed_mismatches{$seq_length}) and ($gu_wobbles <= $allowed_gu_wobbles{$seq_length})) + { + push(@res, $seq_length); + push(@res, $mismatches); + push(@res, $gu_wobbles); + push(@res, 1); + push(@res, 0); + + my @pairings = &FindPairings($subseq, $microrna_sequence, $microrna_start_pairing - 1, -1, $j); + push(@res, $pairings[0]); + push(@res, $pairings[1]); + + #print STDERR "Found loop in mirna at bp " . ($j + 1) . "\n"; + } + } + } + } + + return @res; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub FindPairings +{ + my ($target_sequence, $mirna_sequence, $mirna_skip_start, $target_skip_bp, $mirna_skip_bp) = @_; + + my @pairings; + + my $target_zeros = ""; + my $mirna_zeros = ""; + for (my $i = 0; $i < $mirna_skip_start; $i++) + { + if (length($target_zeros) > 0) { $target_zeros .= ","; } + if (length($mirna_zeros) > 0) { $mirna_zeros .= ","; } + + $target_zeros .= "0"; + $mirna_zeros .= "0"; + } + + my $mirna_index = $mirna_skip_start; + for (my $seq_index = 0; $seq_index < length($target_sequence); $seq_index++) + { + if ($mirna_index - $mirna_skip_start == $mirna_skip_bp) + { + if (length($pairings[1]) > 0 or length($mirna_zeros) > 0) { $mirna_zeros .= ","; } + $mirna_zeros .= "0"; + + $mirna_index++; + } + + if ($seq_index == $target_skip_bp) + { + if (length($pairings[0]) > 0 or length($target_zeros) > 0) { $target_zeros .= ","; } + $target_zeros .= "0"; + } + else + { + my $s1 = substr($target_sequence, $seq_index, 1); + my $s2 = substr($mirna_sequence, $mirna_index, 1); + + my $mismatch = $s1 ne $s2 ? 1 : 0; + #my $gu_wobble = (($s1 eq "G" and $s2 eq "A") or ($s1 eq "A" and $s2 eq "G")) ? 1 : 0; + my $gu_wobble = (($s1 eq "C" and $s2 eq "T") or ($s1 eq "A" and $s2 eq "G")) ? 1 : 0; + + if ($mismatch == 0 or $gu_wobble == 1) + { + $pairings[0] .= $target_zeros; + $pairings[1] .= $mirna_zeros; + $target_zeros = ""; + $mirna_zeros = ""; + + if (length($pairings[0]) > 0 or length($target_zeros) > 0) { $pairings[0] .= ","; } + if (length($pairings[1]) > 0 or length($mirna_zeros) > 0) { $pairings[1] .= ","; } + + $pairings[0] .= $mirna_index + 1; + $pairings[1] .= $seq_index + $mirna_skip_start + 1; + } + else + { + if (length($pairings[0]) > 0 or length($target_zeros) > 0) { $target_zeros .= ","; } + if (length($pairings[1]) > 0 or length($mirna_zeros) > 0) { $mirna_zeros .= ","; } + + $target_zeros .= "0"; + $mirna_zeros .= "0"; + } + + $mirna_index++; + } + } + + return @pairings; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/find_potential_mirna_targets.pl + + Takes in a stab file of targets and a stab file of mirnas, + and outputs locations of potential start sites within the input stab + file, where a mirna-rna interaction may occur. + + Output format: + <# mismatches> <#G:U wobbles> + + -f : The file of the MicroRNAs + + -l : Search for seed lengths of num1,...,num2 to the MicroRNA (default: 6-8) + + -gu : Lengths for which G:U wobbles are allowed and number of allowed wobbles. + Format of nums: ,,... (default: 6;0,7;1,8;1) + + -m : Lengths for which mismatches are allowed and number of allowed mismatches + Format of nums: ,,... + (default: 6;0,7;0,8;1) + + -loop : Lengths for which a single loop in either the target or the microrna is allowed + Format of nums: ,,... (default: none) + + -mb : MicroRNA basepair at which pairing should start (default: 2) + + -min_len : Minimum length of the target when extended beyond the seed (default: 22) + + -random: Output a single random location from each target sequence + + -plm: "Prefer Long Mismatch". If given, then ambigious seeds are reported + as longer seeds with a mismatch. For example, an 8-mer seed with one + G:U wobble at the last position will be reported as an 8-mer with a + G:U wobble rather than the default reporting of a complete match 7-mer. + + diff --git a/modules/local/pita/templates/lib/format_number.pl b/modules/local/pita/templates/lib/format_number.pl new file mode 100755 index 00000000..03fae340 --- /dev/null +++ b/modules/local/pita/templates/lib/format_number.pl @@ -0,0 +1,38 @@ +#!/usr/bin/perl + +use strict; + +sub format_number +{ + my $number = $_[0]; + my $sig_digits = $_[1]; + + my @num = split(/\./, $number); + + my $suffix = ""; + if ($num[1] =~ /(.*)e(.*)/) { $num[1] = $1; $suffix = "e$2"; } + + my $decimal = ""; + + if ($num[0] == 0) + { + my $lsb_len = length($num[1]); + + $num[1] =~ /([1-9].*)/; + + my $significant_len = length($1); + + $decimal = substr($num[1], 0, $lsb_len - $significant_len + $sig_digits); + } + else + { + $decimal = substr($num[1], 0, $sig_digits); + } + + if (length("$decimal$suffix") > 0) { return "$num[0].$decimal$suffix"; } + else { return "$num[0]"; } +} + +#print format_number($ARGV[0],$ARGV[1]) . "\n"; + +1 diff --git a/modules/local/pita/templates/lib/join.pl b/modules/local/pita/templates/lib/join.pl new file mode 100755 index 00000000..b5a40935 --- /dev/null +++ b/modules/local/pita/templates/lib/join.pl @@ -0,0 +1,689 @@ +#!/usr/bin/perl + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libtable.pl"; + +use strict; + +################# BEGIN MAIN ########################### + +my $arg=''; +my (@key1) = (1); +my (@key2) = (1); +my ($beg,$end) = (0,0); +my ($i,$j) = (0,0); +my ($file1,$file2) = ('',''); +my ($key)=''; +my (%values)={}; +my (%exists)={}; +my $delim = "\t"; +my ($delim_in1, $delim_in2) = ("\t","\t"); +my ($delim_out) = ("\t"); +my $delim_syn = "\t"; +my (@tmp) = (); +my ($value1, $value2) = ('',''); +my ($printable, $printable1, $printable2) = ('','',''); +my ($suppress1, $suppress2, $suppressk) = (0,0,0); +my $negate=0; +my ($numeric) = 0; +my $empty = ''; +my $fill = ''; +my ($outer) = 0; +my ($outer_id) = 0; +my ($reverse) = 0; +my ($uppercase) = 0; +my $no_ladder=0; +my $hit = 0; +my $tmp; +my @fill_lines; +my $merge=0; +my $syn_file = "$ENV{JOIN_SYNONYMS}"; +my %syn_pairs; +my $syn_pair; +my @syns_remaining; +my @syn_list; +my %syn_seen; +my $verbose=1; +my $header=0; +my $skip = 0; +my $ignore_missing_file=0; + +while(@ARGV) +{ + $arg = shift @ARGV; + if($arg eq '--help') + { + print STDOUT ; + exit(0); + } + elsif($arg eq '-q') + { + $verbose = 0; + } + elsif($arg eq '-1') + { + $arg = shift @ARGV; + @key1 = &parseRanges($arg); + } + elsif($arg eq '-2') + { + $arg = shift @ARGV; + @key2 = &parseRanges($arg); + } + elsif($arg eq '-o' or $arg eq '--outer') + { + $fill = shift @ARGV; + $outer = 1; + } + elsif($arg eq '-imf') + { + $ignore_missing_file = 1; + } + elsif($arg eq '-of') + { + $arg = shift @ARGV; + if(not(open(FILE, $arg))) + { + print STDERR "Could not open file '$arg' to find outer text, skipping.\n"; + } + else + { + while() + { + if(/\S/) + { + chomp; + push(@fill_lines, $_); + } + } + } + $outer = 1; + } + elsif($arg eq '-oid') + { + $outer_id = 1; + } + elsif($arg eq '-skip') + { + $skip = shift @ARGV; + } + elsif($arg eq '-no_ladder') + { + $no_ladder = 1; + } + elsif($arg eq '-h1') + { + $header = 1; + } + elsif($arg eq '-h2') + { + $header = 2; + } + elsif($arg eq '-e' or $arg eq '--empty') + { + $empty = shift @ARGV; + } + elsif($arg eq '-m') + { + $merge = 1; + } + elsif($arg eq '-num') + { + $numeric = 1; + } + elsif($arg eq '-neg') + { + $negate = 1; + } + elsif($arg eq '-di1') + { + $delim_in1 = shift @ARGV; + } + elsif($arg eq '-di2') + { + $delim_in2 = shift @ARGV; + } + elsif($arg eq '-di') + { + $delim_in1 = shift @ARGV; + $delim_in2 = $delim_in1; + } + elsif($arg eq '-do') + { + $delim_out = shift @ARGV; + } + elsif($arg eq '-ds') + { + $delim_syn = shift @ARGV; + } + elsif($arg eq '-syn') + { + $syn_file = shift @ARGV; + } + elsif($arg eq '-nosyn') + { + $syn_file = ''; + } + + # Suppress printing of values from table 1 (key will be printed however). + elsif($arg eq '-s1') + { + $suppress1 = 1; + } + # Suppress printing of values from table 2 (key will be printed however). + elsif($arg eq '-s2') + { + $suppress2 = 1; + } + elsif($arg eq '-sk') + { + $suppressk = 1; + } + elsif($arg eq '-r' or $arg eq '--reverse' or $arg eq '-rev') + { + $reverse = 1; + } + elsif($arg eq '-u') + { $uppercase = 1; } + + elsif(length($file1)<1) + { + $file1 = $arg; + } + elsif(length($file2)<1) + { + $file2 = $arg; + } +} + +# open(SYN,">tmp_syns"); + +if(@fill_lines and $#fill_lines>=0) +{ + $fill = join($delim_out, @fill_lines); +} + +if($reverse) +{ + $tmp = $suppress1; + $suppress1 = $suppress2; + $suppress2 = $tmp; +} + +# See if the user supplied a synonyms file. If so, extract synonyms for +# keys from the file and load it into a hash. +my %syns; +my $syn; +if(length($syn_file)>0) +{ + if(not(open(FILE, $syn_file))) + { + print STDERR "Could not open the synonyms file, '$syn_file' skipping.\n"; + } + else + { + if($verbose) + { print STDERR "Reading in synonyms from '$syn_file'..."; } + while() + { + chomp; + @tmp = split($delim_syn,$_,-1); + if($uppercase) + { + for($i=0; $i<=$#tmp; $i++) + { + $tmp[$i] =~ tr/a-z/A-Z/; + } + } + if($numeric) + { + for($i=0; $i<=$#tmp; $i++) + { + $tmp[$i] =~ int($tmp[$i]); + } + } + for($i=0; $i<=$#tmp; $i++) + { + if($tmp[$i] =~ /\S/) + { + for($j=0; $j<=$#tmp; $j++) + { + if($tmp[$j] =~ /\S/) + { + $syns{$tmp[$i]} .= $tmp[$j] . $delim_syn; + $syn_pairs{$tmp[$i] . $delim_syn . $tmp[$j]} = 1; + } + } + } + } + } + # Post-process the synonyms: If there are synonyms of synonyms, then make + # sure these are united etc.. + foreach $syn_pair (keys(%syn_pairs)) + { + (@syns_remaining) = split($delim_syn,$syn_pair,-1); + @syn_list=(); + # print SYN '[', join($delim_syn, @syns_remaining), "]: "; + while(@syns_remaining) + { + $syn = shift @syns_remaining; + if(not($syn_seen{$syn})) + { + $syn_seen{$syn} = 1; + push(@syn_list,$syn); + # print SYN "$syn "; + @tmp = split($delim_syn, $syns{$syn},-1); + # Add new synonyms to the list to be processed. + for($j=0; $j<=$#tmp; $j++) + { + push(@syns_remaining, $tmp[$j]); + } + } + } + # print SYN "]\n"; + for($i=0; $i<=$#syn_list; $i++) + { + $syns{$syn_list[$i]} = ''; + for($j=0; $j<=$#syn_list; $j++) + { + $syns{$syn_list[$i]} .= $syn_list[$j]; + if($j<$#syn_list) + { + $syns{$syn_list[$i]} .= $delim_syn; + } + } + # print SYN "[$syn_list[$i]] <=> [$syns{$syn_list[$i]}]\n"; + } + } + + close(FILE); + if($verbose) + { print STDERR " done.\n"; } + } +} + +# $arg = $syns{'F27B3.1'}; +# print "[$arg]\n"; + +if(length($file1)<1 or length($file2)<1) +{ + print STDERR ; + exit(1); +} + +if ($ignore_missing_file and !(-e $file1) and ($file1 ne "-")){ + open(F2,$file2); + while(my $line=){ + my %check; + chomp $line; + my @tmp=split /$delim_in2/,$line,-1; + my @out; + for my $i (@key2){ + push @out,$tmp[$i-1]; + $check{$i-1}=1; + } + for (my $i=0;$i){ + my %check; + chomp $line; + my @tmp=split /$delim_in1/,$line,-1; + my @out; + for my $i (@key1){ + push @out,$tmp[$i-1]; + $check{$i-1}=1; + } + for (my $i=0;$i $b} @key1; +@key2 = sort {$a <=> $b} @key2; + +# print STDERR "Key 1: [", join(',', @key1), "]\n", +# "Key 2: [", join(',', @key2), "]\n", +# "Input delimiter 1: [$delim_in1]\n", +# "Input delimiter 2: [$delim_in2]\n", +# "Output delimiter 1: [$delim_out1]\n", +# "Output delimiter 2: [$delim_out2]\n", +# "\n", +# ; + +# Read in the key-printable pairs from the second file: +my ($loops) = 0; +my ($passify) = 10000; +my $file_ref; +if($file2 =~ /\.gz$/) +{ + open(FILE, "zcat < $file2 |") or die("Could not open file '$file2'."); + $file_ref = \*FILE; +} +elsif($file2 eq '-') +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file2) or die("Could not open file '$file2'."); + $file_ref = \*FILE; +} +if($verbose) +{ + print STDERR "Reading relations from ", $file2 eq '-' ? "standard input" + : "file $file2"; +} +my $header_data=''; +my $line=0; +while(<$file_ref>) +{ + if(/\S/ and (!(/^\s*#/) or $no_ladder)) + { + $line++; + if($line==1 and $header==2) + { $header_data = $_; } + chomp; + @tmp = split($delim_in2,$_,-1); +# print STDERR "\n2: tmp: [", join('|',@tmp), "]\n"; +# print STDERR "2: key cols: [", join('|',@key2), "]\n"; + $key=''; + for($i=$#key2; $i>=0; $i--) + { + my $key_part = splice(@tmp,$key2[$i], 1); + # $key .= length($key)>0 ? ($delim_out . $key_part) : $key_part; + $key = length($key)>0 ? ($key_part . $delim_out . $key) : $key_part; +# print STDERR "1: key: [$key]\n"; +# print STDERR "Before splice: [", join('|',@tmp), "] [$key]\n"; +# print STDERR "After splice: [", join('|',@tmp), "] [$key]\n"; + # $key .= splice(@tmp, $i-1, 1) . $delim_out; + } + # Get rid of the last delimiter we added: + if($numeric) + { $key = int($key); } + if($uppercase) + { $key =~ tr/a-z/A-Z/; } +# print STDERR "2: tmp: [", join('|',@tmp), "]\n"; +# print STDERR "2: key: [$key]\n"; + $tmp = join($delim_out, @tmp); + if ($#tmp<0){$tmp="--BLANKNOPRINT--"} + $values{$key} = $tmp; + $exists{$key} = 1; + + # Record this value with all the synonym keys as well. + + @tmp = split($delim_syn, $syns{$key},-1); + # foreach $key (@tmp) + for($j=0; $j<=$#tmp; $j++) + { + if($numeric) + { $key = int($key); } + if($uppercase) + { $key =~ tr/a-z/A-Z/; } + $values{$key} = $tmp; + $exists{$key} = 1; + } + + $loops++; + if($verbose and $loops%$passify==$passify-1) + { + print STDERR '.'; + } + } +} +if($verbose) + { print STDERR " done.\n"; } +close($file_ref); + +# $arg = $syn{'F15G10.1'}; +# print STDERR "[$arg]\n"; + +# Read in the key-printable pairs from the first file and print out +# the joined key: +my $file_ref; +if($file1 =~ /\.gz$/) +{ + open(FILE, "zcat < $file1 |") or die("Could not open file '$file1'."); + $file_ref = \*FILE; +} +elsif($file1 eq '-') +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file1) or die("Could not open file '$file1'."); + $file_ref = \*FILE; +} +if($verbose) + { print STDERR "Joining on file $file1"; } +$loops=0; +my $found; +while(<$file_ref>) + { + if ($skip > $loops) + { + $loops++; + print; + } + elsif(/\S/ and (!(/^\s*#/) or $no_ladder)) + { + chomp; + @tmp = split($delim_in1,$_,-1); + $key=''; + for($i=$#key1; $i>=0; $i--) + { + my $key_part = splice(@tmp,$key1[$i], 1); + $key = length($key)>0 ? ($key_part . $delim_out . $key) : $key_part; + } + # Get rid of the last delimiter we added: + if($numeric) + { $key = int($key); } + if($uppercase) + { $key =~ tr/a-z/A-Z/; } + + $value1 = join($delim_out, @tmp); + if ($#tmp<0){$value1="--BLANKNOPRINT--"} + $value2 = $values{$key}; + $found = $exists{$key}; + +# print STDERR "1: key: [$key]\n"; +# print STDERR "1: value1: [$value1]\n"; +# print STDERR "1: value2: [$value2]\n"; +# print STDERR "1: found: [$found]\n"; + + # See if this key matches any of the key's synonyms + if(not($found)) + { + + @tmp = split($delim_syn, $syns{$key},-1); + while(@tmp and not($found)) + { + $tmp = shift @tmp; + $found = $exists{$tmp}; + if($found) + { + $value2 = $values{$tmp}; + } + } + } + + if((not($negate) and $found)) + { + $hit = 1; + } + elsif($negate and not($found)) + { + $hit=1 ; + $value2 = "--BLANKNOPRINT--"; + } + elsif($outer) + { + $value2 = $fill; + if ($value2 eq ""){$value2 = "--BLANKNOPRINT--"} + $hit = 1; + } + elsif($outer_id) + { + $value2 = $key; + $hit = 1; + } + else + { + $hit = 0; + } + + if($merge & $hit) + { + $value1 = $value2; + $value2 = "--BLANKNOPRINT--"; + } + elsif($merge & not($hit)) + { + $hit = 1; + $value2 = "--BLANKNOPRINT--"; + } + + if($hit) + { + # Swap the two values if we're supposed to print the second value + # before the first value. + if($reverse) + { + $tmp = $value1; + $value1 = $value2; + $value2 = $tmp; + } + + my @printed; + + if(!$suppressk){push @printed,$key} + if(!$suppress1 and $value1 ne "--BLANKNOPRINT--"){push @printed,length($value1)<1?$empty:$value1} + if(!$suppress2 and $value2 ne "--BLANKNOPRINT--"){push @printed,length($value2)<1?$empty:$value2} + print join($delim,@printed),"\n"; + } + + $loops++; + if($verbose and $loops%$passify==$passify-1) + { + print STDERR '.'; + } + } + } +if($verbose) + { print STDERR " done.\n"; } +close(FILE); + +exit(0); + +################# END MAIN ############################# + +__DATA__ +syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/join.pl [OPTIONS] FILE1 FILE2 + +This script takes two tables, contained in delimited files, as input and +produces a new table that is a join of FILE1 and FILE2. The script assumes +the keys can be found in the first column of the two files and that columns +are delimited by single tabs (both of these assumptions can be changed, see +OPTIONS). If FILE1 contains the tuple (A, W, X) and FILE2 contains the +tuple (A, Y, Z) then (A, W, X, Y, Z) will be contained in the output. +NOTE: FILE2 will be loaded into memory. + +OPTIONS are: + +-m: Merge - if key exists in file 2, use value from file 2 else + use the value from file 1. +-q: Quiet mode: turn verbosity off (default is verbose) + +-1 COL: Include column COL from FILE1 as part of the key (default is 1). + Multiple columns may be specified in which case keys are constructed + by concaternating each column in the order specified (delimiting + character used equal to the output delimiter, see -do flag). + +-2 COL: Include column COL from FILE2 as part of the key (default is 1). + See -1 option for discussion of multiple columns. + +-skip NUM: Skip the first NUM lines of FILE1 and print them as they are (first line + is 1, default value is 0). +-o FILL: Do a left outer join. If a key in FILE1 is not in FILE2, then the +--outer tuple from FILE1 is printed along with the text in FILL in place of + a tuple from FILE2 (by default these tuples are not reported in the + result). See -of option also to supply FILL from a file, and -oid to replace + FILL with the id from FILE1. + +-of FILE: Same as -o, but use the text in FILE as the text to FILL. + +-oid: Same as -o, but use the id from FILE1 as the text to FILL. + +-e EMPTY: Set the empty string to EMPTY (default is blank). If both keys + exist in FILE1 and FILE2 but one tuple is blank, then the empty + character EMPTY will be printed. + +-num: Treat the keys as numeric quantities (default is off: treat keys as + strings). If this is turned on, each key will be forced into an + integer quantity. + +-neg: Negative output -- print out the keys from FILE1 that are not in FILE2. + These are equivalent to those keys that would be left out of the join + or those that would have a FILL tuple in a left outer join (see -o + option). + +-di1 DELIM: Set the input delimiter for FILE1 to DELIM (default is tab). + +-di2 DELIM: Set the input delimiter for FILE2 to DELIM (default is tab). + +-di DELIM: Set the input delimiters for both FILE1 and FILE2 to DELIM (default + is tab). Equivalent to using both the -di1 and -di2 options. + +-do DELIM: Set the output delimiter to DELIM. Note there is only one output + delimiter (not two: one for FILE1 and FILE2); this forces the + output to a common delimitation (default is tab). + +-ds DELIM: Set the delimiter for synonyms to DELIM. This is used for reading + synonyms for keys (see the -syn option) (default is tab). + +-syn FILE: Specify that synonyms for keys can be found in the file FILE. + Each line in FILE should contain synonyms for only one key, seperated + by the delimiter specified with the -ds option). + +-nosyn: Ignore synonym file in the JOIN_SYNONYMS environment variable if it + exists. + +-s1: Suppress printing of tuples from FILE1. The key is printed, followed by + the tuple found in FILE2. + +-s2: Suppress printing of tuples from FILE2. + +-sk: Suppress printing of keys. + +-r: Reverse -- Instead of printing , print + where is the key, is a tuple + found from FILE1 and is a tuple found in FILE2. + +-u: Uppercase. For non-numeric keys, force any letter to be uppercase before + attempting to do key lookups. Keys from both FILE1 and FILE2 will be + converted to uppercase before attempting the join. + +-imf: Ignore missing file. If file1 does not exist, simply print file2 (and + vice versa). +-no_ladder: Turn off default behavior of ignoring lines with # + diff --git a/modules/local/pita/templates/lib/libfile.pl b/modules/local/pita/templates/lib/libfile.pl new file mode 100755 index 00000000..495d7c52 --- /dev/null +++ b/modules/local/pita/templates/lib/libfile.pl @@ -0,0 +1,1672 @@ +use strict; + +sub fileFriendlyName +{ + my ($name) = @_; + + $name =~ s/\//_/g; + $name =~ s/\\/_/g; + $name =~ s/"/_/g; + $name =~ s/'/_/g; + $name =~ s/\(/_/g; + $name =~ s/\)/_/g; + $name =~ s/\[/_/g; + $name =~ s/\]/_/g; + $name =~ s/\{/_/g; + $name =~ s/\}/_/g; + $name =~ s/ +/_/g; + + $name =~ s/_[_]+/_/g; + + return $name; +} + +sub readFile +{ + my ($file) = @_; + my @lines; + while(my $line = <$file>) + { + chomp($line); + push(@lines, $line); + } + return \@lines; +} + +sub readFileName +{ + my ($file_name) = @_; + my $file = &openFile($file_name, "r"); + my $lines = &readFile($file); + close($file); + return $lines; +} + +##------------------------------------------------------------------------ +## \*FILE openFile ($string file_name=undef, $string purpose="r") +##------------------------------------------------------------------------ +sub openFile +{ + my $file_name = shift; + my $purpose = shift; + $file_name = defined($file_name) ? $file_name : '-'; + $purpose = defined($purpose) ? $purpose : 'r'; + my $file = undef; + if($file_name eq '-') + { + # Read-only files + if($purpose =~ /^ *r/i) + { + $file = \*STDIN; + } + # Overwrite the file + elsif($purpose =~ /^ *w/i or $purpose =~ /^ *a/i) + { + $file = \*STDOUT; + } + } + else + { + # Read-only files + if($purpose =~ /^ *r/i or not(defined($purpose))) + { + if($file_name =~ /\.gz$/ or $file_name =~ /\.Z$/) + { + $file_name = "zcat $file_name |"; + } + else + { + $file_name = "<$file_name"; + } + } + # Overwrite + elsif($purpose =~ /^ *w/i) + { + $file_name = ">$file_name"; + } + # Append + elsif($purpose =~ /^ *a/i) + { + $file_name = ">>$file_name"; + } + + if(not(open($file, $file_name))) + { + $file = undef; + } + } + return $file; +} + +sub printFilep +{ + my ($file_in, $file_out) = @_; + $file_in = defined($file_in) ? $file_in : \*STDIN; + $file_out = defined($file_out) ? $file_out : \*STDOUT; + + while(my $line = <$file_in>) + { + print $file_out $line; + } +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub GetNumColumns +{ + my ($file_name) = @_; + + my $rows = `head -1 $file_name | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/transpose.pl | wc -l`; + + $rows =~ /^ *([^ ]+)/; + + return $1; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub GetNumRows +{ + my ($file_name) = @_; + + my $rows = `wc -l $file_name`; + + $rows =~ /^ *([^ ]+)/; + + return $1; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub GetAllDirs +{ + return &getAllDirs(@_); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getAllDirs +{ + my @dirs = @_; + my @subdirs; + foreach my $dir (@dirs) + { + my $dirp; + if(opendir($dirp, $dir)) + { + my @files = readdir($dirp); + foreach my $file (@files) + { + my $path = $dir . '/' . $file; + if ((-d $path) and (not($file =~ /^\.\.$/)) and (not($file =~ /^\.$/))) + { + push(@subdirs, $path); + } + } + closedir($dirp); + } + } + return @subdirs; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getAllFiles +{ + my @dirs = @_; + my @paths; + foreach my $dir (@dirs) + { + my $dirp; + if(opendir($dirp,$dir)) + { + my @files = readdir($dirp); + foreach my $file (@files) + { + push(@paths, $dir . '/' . $file); + } + closedir($dirp); + } + } + return @paths; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getAllFilesRecursively # ($follow_links,@dirs) +{ + my $follow_links = shift; + my @dirs = @_; + my @files = (); + my @allEntries; + my @entries; + my $entry; + my $subEntry; + + foreach $entry (@dirs) + { + if(-d $entry and ($follow_links or not(-l $entry))) + { + if(opendir(DIR,$entry)) + { + @allEntries = readdir(DIR); + @entries = (); + while(@allEntries) + { + $subEntry = shift @allEntries; + if($subEntry ne '..' and $subEntry ne '.') + { + if($entry =~ /\/$/) + { + push(@entries, $entry . $subEntry); + } + else + { + push(@entries, $entry . '/' . $subEntry); + } + } + } + closedir(DIR); + push(@files, &getAllFilesRecursively($follow_links,@entries)); + } + else + { + print STDERR "Could not open directory -->$entry<-- skipping.\n"; + } + } + elsif(-f $entry) + { + push(@files,$entry); + } + } + return @files; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getAllCodeRecursively # ($follow_links,@dirs) +{ + my $follow_links = shift; + my @dirs = @_; + my @files = (); + my @allEntries; + my @entries; + my $entry; + my $subEntry; + + foreach $entry (@dirs) + { + if(-d $entry and ($follow_links or not(-l $entry))) + { + if(opendir(DIR,$entry)) + { + @allEntries = readdir(DIR); + # print STDERR "[[$allEntries[0] $allEntries[1]]]\n"; + @entries = (); + while(@allEntries) + { + $subEntry = shift @allEntries; + if($subEntry ne '..' and $subEntry ne '.') + { + if($entry =~ /\/$/) + { + push(@entries, $entry . $subEntry); + } + else + { + push(@entries, $entry . '/' . $subEntry); + } + } + } + closedir(DIR); + push(@files, &getAllCodeRecursively($follow_links,@entries)); + } + else + { + print STDERR "Could not open directory -->$entry<-- skipping.\n"; + } + } + elsif(-f $entry and isCodeFile($entry)) + { + push(@files,$entry); + } + } + return @files; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getPathPrefix +{ + my $path = shift @_; + + $path =~ s/[^\/]*[\/]*$//; + return $path; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getPathSuffix +{ + my $path = shift @_; + + while($path =~ /\/$/) + { + chop($path); + } + if($path =~ /([^\/]+)$/) + { + $path = $1; + } + return $path; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub remPathExt +{ + my $path = shift @_; + + $path =~ s/\.[^\.]*$//; + + return $path; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getPathExt +{ + my $path = shift @_; + + my $ext = ''; + if($path =~ /(\.[^\.]*)$/) + { + $ext = $1; + } + + return $ext; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub expandPath +{ + my $file = shift @_; + my $home = "$ENV{HOME}"; + + # print STDERR "'$file' --> "; + $file =~ s/^ +//; + $file =~ s/ +$//; + $file =~ s/~/$home/ge; + $file =~ s/\$HOME/$home/ge; + $file =~ s/\$\(HOME\)/$home/ge; + $file =~ s/\$\{HOME\}/$home/ge; + # print STDERR "'$file'\n"; + + return $file; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub resolvePath # ($file,$pwd) +{ + my $file = &expandPath(shift); + my $pwd = shift; + $pwd =~ s/[\/]+ *$//; + + $file = &isRelative($file) ? ($pwd . '/' . $file) : $file; + + return $file; +} + +##------------------------------------------------------------------------ +## Returns the depth of the file from the root directory. +##------------------------------------------------------------------------ +sub getPathDepth +{ + my $file = &expandPath(shift); + # Remove any leading ./ that indicate "current" directory. + while($file =~ s/^\.\///) {} + + my $depth=0; + for(; $file =~ /\S/; $file = &getPathPrefix($file)) + { $depth++; } + + return $depth; +} + + +##------------------------------------------------------------------------ +## Returns 1 if the file is an absolute path, 0 otherwise. +##------------------------------------------------------------------------ +sub isAbsolute # ($file) +{ + my $file = &expandPath(shift); + + # If the first symbol is /, it's absolute. + return ($file =~ /^ *\//); +} + +##------------------------------------------------------------------------ +## Returns 1 if the file is a relative path, 0 otherwise. +##------------------------------------------------------------------------ +sub isRelative # ($file) +{ + my $file = shift; + return not(&isAbsolute($file)); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub dos2unix +{ + my $file = shift @_; + + $file =~ s/\\/\//g; + $file =~ s/[Cc]:/\/cygdrive\/c/; + + return $file; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub isCodeFile +{ + my $file = shift; + + if(not(-f $file)) + { + return 0; + } + + if($file =~ /\.c$/i) { return 1; } + if($file =~ /\.cc$/i) { return 1; } + if($file =~ /\.cpp$/i) { return 1; } + if($file =~ /\.h$/i) { return 1; } + if($file =~ /\.hh$/i) { return 1; } + if($file =~ /\.htm$/i) { return 1; } + if($file =~ /\.html$/i) { return 1; } + if($file =~ /\.hpp$/i) { return 1; } + if($file =~ /\.java$/i) { return 1; } + if($file =~ /\.mak$/i) { return 1; } + if($file =~ /\.map$/i) { return 1; } + if($file =~ /\.pl$/i) { return 1; } + if($file =~ /\.pm$/i) { return 1; } + if($file =~ /\.py$/i) { return 1; } + if($file =~ /\.m$/i) { return 1; } + if($file =~ /\.s$/i) { return 1; } + if($file =~ /\.y$/i) { return 1; } + if($file =~ /Makefile/) { return 1; } + if($file =~ /Makefile\.common/) { return 1; } + + return 0; +} + + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub isObjectFile +{ + my $file = shift; + + if(not(-f $file)) + { + return 0; + } + + if($file =~ /\.o$/i) { return 1; } + if($file =~ /\.so$/i) { return 1; } + + return 0; +} + + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub protectFromShell # ($file) +{ + my $file = shift; + $file =~ s/([ ~"')(&])/\\$1/g; + return $file; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub deprotectFromShell # ($file) +{ + my $file = shift; + $file =~ s/\\([^\\])/$1/g; + return $file; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub getFileText # ($file_name) +{ + my $file_name = shift; + + if (defined($file_name)) + { + my $file = &openFile($file_name,'r'); + my @text = <$file>; + my $text = join("",@text); + return $text; + } + else + { + return ""; + } +} + +##------------------------------------------------------------------------ +## $int numRows ($string file_name, $int blanks=1) +##------------------------------------------------------------------------ +sub numRows +{ + my ($file_name, $blanks) = @_; + + $blanks = defined($blanks) ? $blanks : 1; + + my $num_rows = 0; + + if(-f $file_name) + { + my $wc = $blanks ? (`wc $file_name`) : (`grep -v '^[ ][ ]*\$' $file_name | wc`); + + my @wc = split(/ +/, $wc); + + $num_rows = $wc[1]; + } + return $num_rows; +} + +sub pad +{ + my ($list, $filler) = @_; + + my @padded; + + for(my $i = 0; $i < scalar(@{$filler}); $i++) + { + push(@padded, defined($$list[$i]) ? $$list[$i] : $$filler[$i]); + } + + return \@padded; +} + +##------------------------------------------------------------------------ +## $string fill ($int max_cols, \@list filling=[''], $int pad=0, +## $string delim="\t", $string line=$_) +##------------------------------------------------------------------------ +sub fill +{ + my ($max_cols, $filling, $pad, $delim, $line) = @_; + $pad = defined($pad) ? $pad : 0; + $delim = defined($delim) ? $delim : "\t"; + $line = defined($line) ? $line : $_; + + my $chomped = 0; + if($line =~ /\n$/) + { + chomp($line); + $chomped = 1; + } + + my @tuple = split($delim, $line); + my $num_cols = scalar(@tuple); + my $num_fill = defined($filling) ? scalar(@{$filling}) : 0; + + if(not($pad)) + { + for(my $i = 0; $i < $num_cols; $i++) + { + if(length($tuple[$i]) == 0 and $num_fill > 0) + { + $tuple[$i] = $$filling[$i % $num_fill]; + } + } + } + + for(my $i = $num_cols; $i < $max_cols; $i++) + { + my $filler = $num_fill > 0 ? $$filling[$i % $num_fill] : ''; + push(@tuple, $filler); + } + + my $filled = join($delim, @tuple); + + if($chomped) + { + $filled .= "\n"; + } + + return $filled; +} + +##------------------------------------------------------------------------ +## $int numTokens ($string delim="\t", $string line=$_) +##------------------------------------------------------------------------ +sub numTokens +{ + my ($delim, $line) = @_; + $delim = defined($delim) ? $delim : "\t"; + $line = defined($line) ? $line : $_; + return scalar(split($delim, $line)); +} + +##------------------------------------------------------------------------ +## $int numCols ($string file='-', $string delim="\t", \$string eaten=undef) +## +## Takes a file name as an argument. If the file is STDIN then it has to +## eat a line to determine the columns. This eaten line is saved in +## eaten if supplied. +##------------------------------------------------------------------------ +sub numCols +{ + my ($file, $delim, $eaten) = @_; + $file = defined($file) ? $file : '-'; + $delim = defined($delim) ? $delim : "\t"; + + my $filep; + open($filep, $file) or die("Could not open file '$file'"); + my $num_cols = &numCols2($filep, $delim, $eaten); + + if($file ne '-') + { + close($filep); + $$eaten = undef; + } + + return $num_cols; +} + +##----------------------------------------------------------------------------- +## $int numCols2 (\*FILE file=\*STDIN, $string delim="\t", \$string eaten=undef) +## +## Takes a file pointer as an argument. +## +## Eats a line of the file to figure out how many columns there are. +##----------------------------------------------------------------------------- +sub numCols2 +{ + my ($file, $delim, $eaten) = @_; + + $file = defined($file) ? $file : \*STDIN; + $delim = defined($delim) ? $delim : "\t"; + + my $line = <$file>; + my $num_cols = &numTokens($delim, $line); + + if(defined($eaten)) + { + $$eaten = $line; + } + + return $num_cols; +} + +##------------------------------------------------------------------------ +## $int maxCols ($string file='-', $string delim="\t", \@list eaten=undef) +## +## Takes a file name as an argument. If the file is STDIN then it has to +## eat a line to determine the columns. This eaten line is saved in +## eaten if supplied. +##------------------------------------------------------------------------ +sub maxCols +{ + my ($delim, $file, $eaten) = @_; + + $file = defined($file) ? $file : '-'; + + $delim = defined($delim) ? $delim : "\t"; + + my $filep; + + open($filep, $file) or die("Could not open file '$file'"); + + my $max_cols = 0; + + while(my $line = <$filep>) + { + my $num_cols = &numTokens($delim, $line); + + if($num_cols > $max_cols) + { + $max_cols = $num_cols; + } + + if($file eq '-' and defined($eaten)) + { + push(@{$eaten}, $line); + } + } + close($filep); + + return $max_cols; +} + +##---------------------------------------------------------------------------- +## \@list &readHeader(\*FILE file=\*STDIN, $int num_rows=1, $string delim="\t") +# +# Read columns from the file. Returns a list containing each column +# where the elements in the column are seperated by delim. +##---------------------------------------------------------------------------- +sub readHeader +{ + my ($file, $num_rows, $delim_in, $delim_out) = @_; + $file = defined($file) ? $file : \*STDIN; + $num_rows = defined($num_rows) ? $num_rows : 1; + $delim_in = defined($delim_in) ? $delim_in : "\t"; + $delim_out = defined($delim_out) ? $delim_out : $delim_in; + + my @column; + + for(my $i = 0; ($i < $num_rows) and not(eof($file)); $i++) + { + my $line = <$file>; + + my @tuple = split($delim_in, $line); + + chomp($tuple[$#tuple]); + + for(my $j = 0; $j < scalar(@tuple); $j++) + { + $column[$j] .= ($i == 0) ? $tuple[$j] : ($delim_out . $tuple[$j]); + } + } + + return \@column; +} + +sub duplicate +{ + my ($num_copies, @entries) = @_; + + $num_copies = defined($num_copies) ? $num_copies : 1; + + if(scalar(@entries) == 0) + { + push(@entries, ''); + } + + my @tuple; + + for(my $i = 0; $i < $num_copies; $i++) + { + push(@tuple, @entries); + } + + return \@tuple; +} + +##---------------------------------------------------------------------------- +## \@list &getCols(\@list, $string ranges, \$int max_cols) +##---------------------------------------------------------------------------- +sub getCols +{ + my ($list, $ranges, $max_cols) = @_; + + if(defined($list) and defined($ranges) and defined($max_cols)) + { + my $num_cols = scalar(@{$list}); + my $updated = 0; + if($num_cols > $$max_cols) + { + $$max_cols = $num_cols; + if(defined($ranges)) + { + my @cols = &parseRanges($ranges, $$max_cols); + for(my $i = 0; $i < scalar(@cols); $i++) + { + $cols[$i]--; + } + return \@cols; + } + } + } + return undef; +} + + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub fileExists +{ + my ($file) = @_; + return (-f $file); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub dirExists +{ + my ($dir) = @_; + return (-d $dir); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub linkExists +{ + my ($link) = @_; + return (-l $link); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub pathExists +{ + my ($path) = @_; + return ((-f $path) or (-d $path) or (-l $path)); +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub allFilesExist +{ + foreach my $file (@_) + { + if(not(&fileExists($file))) + { + return 0; + } + } + return 1; +} + +##------------------------------------------------------------------------ +## +##------------------------------------------------------------------------ +sub allPathsExist +{ + foreach my $path (@_) + { + if(not(&pathExists($path))) + { + return 0; + } + } + return 1; +} + +##------------------------------------------------------------------------ +## \@list getHeader ($string file, $int num_lines=1, $string delim="\t" +## \$FILE* filep) +## +## \$FILE* filep - If supplied gets a copy of the file pointer (and +## the file is *not* closed but kept open). +##------------------------------------------------------------------------ +sub getHeader +{ + my ($file, $num_lines, $delim, $filep) = @_; + $num_lines = defined($num_lines) ? $num_lines : 1; + $delim = defined($delim) ? $delim : "\t"; + + my $fp; + open($fp, $file) or die("Could not open file '$file'"); + + my @header; + for(my $i = 0; $i < $num_lines; $i++) + { + my $line = <$fp>; + my @line = split($delim, $line); + chomp($line[$#line]); + + for(my $j = 0; $j < scalar(@line); $j++) + { + $header[$j] .= length($header[$j]) > 0 ? " $line[$j]" : $line[$j]; + } + } + + if(not(defined($filep))) + { + close($fp); + } + else + { + $$filep = $fp; + } + + return \@header; +} + +#------------------------------------------------------------------------ +# @list parseRanges ($string ranges, $int last_col, $int offset=0) +#------------------------------------------------------------------------ +sub parseRanges +{ + my ($ranges, $last_col, $offset) = @_; + $offset = defined($offset) ? $offset : 0; + + my @segments = (); + my @range = (); + my @fields = (); + my ($i,$beg,$end,$inc) = (0,-1,-1,1); + my $seg; + @segments = split(",", $ranges); + foreach $seg (@segments) + { + $beg = undef; + $end = undef; + $inc = undef; + + if($seg =~ /^([-]{0,1}\d+)[-:](\d+)[-:]([-\d]*)/) + { + $beg = $1; + $inc = $2; + $end = $3; + } + elsif($seg =~ /^([-]{0,1}\d+)[:-]([-\d]*)/) + { + $beg = $1; + $end = $2; + $inc = 1; + } + elsif($seg =~ /^([-\d]+)/) + { + $beg = $1; + $end = $1; + $inc = 1; + } + + $beg = (defined($beg) and $beg =~ /\S/) ? $beg : 0; + $beg = (defined($beg) and $beg < 0) ? (defined($last_col) ? $last_col + $beg + 1 : undef) : $beg; + $end = (defined($end) and $end =~ /\S/) ? $end : (defined($last_col) ? $last_col : undef); + $end = (defined($end) and $end < 0) ? (defined($last_col) ? $last_col + $end + 1 : undef) : $end; + $inc = $inc =~ /\S/ ? $inc : 1; + + if(defined($beg) and defined($end) and defined($inc)) + { + for($i = $beg; $i <= $end; $i += $inc) + { + push(@fields, $i); + } + } + } + + if($offset != 0) + { + for(my $i = 0; $i < scalar(@fields); $i++) + { + $fields[$i] += $offset; + } + } + + return @fields; +} + +##-------------------------------------------------------------------------------------- +## $int evalRegex ($string value=$_, $string regex='/\S/', +## $string op='=~', $string hardop=undef, $int negate=0) +## +## Returns 1 if the regular expression evaluates to true. +## +## hardop - supplies a specific operation. Valid are: +## 'gt' for $value > $regex +## 'gte' for $value >= $regex +## 'lt' for $value < $regex +## 'lte' for $value <= $regex +##-------------------------------------------------------------------------------------- +sub evalRegex +{ + my ($value, $regex, $op, $hardop, $negate) = @_; + $value = defined($value) ? $value : $_; + $regex = defined($regex) ? $regex : '/\S/'; + $op = defined($op) ? $op : '=~'; + $hardop = defined($hardop) ? $hardop : undef; + $negate = defined($negate) ? $negate : 0; + + my $result = 0; + + if(not(defined($hardop))) + { + $result = $negate ? eval("not(\$value $op $regex);") : + eval("\$value $op $regex;"); + $result = (defined($result) and $result) ? 1 : 0; + } + elsif($hardop eq 'eq') + { + $result = $value eq $regex ? 1 : 0; + } + elsif($hardop eq 'ne') + { + $result = $value ne $regex ? 1 : 0; + } + elsif($hardop eq 'gt') + { + $result = $value gt $regex ? 1 : 0; + } + elsif($hardop eq 'lt') + { + $result = $value lt $regex ? 1 : 0; + } + elsif($hardop eq 'gte') + { + $result = (($value gt $regex) or ($value eq $regex)) ? 1 : 0; + } + elsif($hardop eq 'lte') + { + $result = (($value lt $regex) or ($value eq $regex)) ? 1 : 0; + } + elsif($hardop eq '=') + { + $result = $value == $regex ? 1 : 0; + } + elsif($hardop eq '==') + { + $result = $value == $regex ? 1 : 0; + } + elsif($hardop eq '!=') + { + $result = $value != $regex ? 1 : 0; + } + elsif($hardop eq '>') + { + $result = $value > $regex ? 1 : 0; + } + elsif($hardop eq '>=') + { + $result = $value >= $regex ? 1 : 0; + } + elsif($hardop eq '<') + { + $result = $value < $regex ? 1 : 0; + } + elsif($hardop eq '<=') + { + $result = $value <= $regex ? 1 : 0; + } + return $result; +} + +##------------------------------------------------------------------------ +## \%attrib parseArgs (\@list args, \@list flag_tuples, $int store_extra=0) +## +## \@args - list of arguments (from @ARGV usually) +## +## \@flag_tuples - a list of triples where each triple gives: +## +## (FLAG,TYPE,DEFAULT,EATS) +## +## for each option. FLAG is the string (or regular expression) +## that indicates use of the option (including the dash if +## dashes are being used!). DEFAULT is the default value for +## the option used when the option's flag is not found in the +## argument list. If EATS is defined then the next argument in +## \@args is "eaten" to retrieve the value for the option; if +## EATS is undef then it does *not* eat the next character +## but fills in the string contained in EATS for the option +## when its flag is encountered. TYPE can be any of: +## +## 'scalar' - the option is a scalar quantity +## 'list' - the option is a list +## 'set' - the option is a set +## 'map' - the option is an associative array +## 'file' - the option is the name of a file +## +## +## The special FLAG '--file' reads a file from the arguments. +## +## $store_extra - If 1 stores unrecognized arguments in a list that can +## be accessed with '--extra'. Otherwise the function +## dies if an unrecognized argument is encountered (default) +## +##------------------------------------------------------------------------ +sub parseArgs +{ + my ($args, $flag_tuples, $store_extra) = @_; + $store_extra = defined($store_extra) ? $store_extra : 0; + + my @args = defined($args) ? @{$args} : (); + my @f = defined($flag_tuples) ? @{$flag_tuples} : (); + my %options; + my %option_overwritten; + my @extra; + + # Store the defaults in the options. + for(my $i = 0; $i < scalar(@f); $i++) + { + my ($flag, $type, $default, $eats) = ($f[$i][0],$f[$i][1],$f[$i][2],$f[$i][3]); + $options{$flag} = $default; + } + + while(@args) + { + my $arg = shift @args; + if($arg eq '--help') + { + @args = (); + $options{'--help'} = 1; + } + else + { + my $matched_arg = 0; + for(my $i = 0; $i < scalar(@f); $i++) + { + my ($flag, $type, $default, $eats) = ($f[$i][0],$f[$i][1],$f[$i][2],$f[$i][3]); + + if(($flag =~ /^--file/ and ((-f $arg) or ($arg eq '-'))) or + ($arg eq $flag)) + { + $matched_arg = 1; + my $value = $arg; + if(defined($eats)) + { + $value = $eats; + } + elsif(not($flag =~ /^--file/)) + { + $value = shift @args; + } + + if($type eq 'scalar') + { + $options{$flag} = $value; + } + elsif($type eq 'list') + { + if(not(defined($option_overwritten{$flag}))) + { + my @empty_list; + $options{$flag} = \@empty_list; + } + my $list = $options{$flag}; + push(@{$list}, $value); + } + elsif($type eq 'set') + { + if(not(defined($option_overwritten{$flag}))) + { + my %empty_set; + $options{$flag} = \%empty_set; + } + my $set = $options{$flag}; + $$set{$value} = 1; + } + elsif($type eq 'map') + { + if(not(defined($option_overwritten{$flag}))) + { + my %empty_map; + $options{$flag} = \%empty_map; + } + my ($attrib,$val) = split('=',$value); + my $map = $options{$flag}; + $$map{$attrib} = $val; + } + $option_overwritten{$flag} = 1; + } + } + if(not($matched_arg)) + { + if($store_extra) + { + push(@extra, $arg); + } + else + { + die("Bad argument '$arg' given"); + } + } + } + } + + # If we picked up any extra arguments put them in the hash. + $options{'--extra'} = \@extra; + + return \%options; +} + +sub readKeyedTuples +{ + my ($file, $delim, $key_col, $headers) = @_; + $file = defined($file) ? $file : $_; + $delim = defined($delim) ? $delim : "\t"; + $key_col = defined($key_col) ? $key_col : 0; + $headers = defined($headers) ? $headers : 0; + + my %set; + + my $filep = &openFile($file); + my $line_no = 0; + while(<$filep>) + { + $line_no++; + if($line_no > $headers) + { + my @x = split($delim); + chomp($x[$#x]); + my $key = splice(@x, $key_col, 1); + $set{$key} = \@x; + } + } + + return \%set; +} + +sub download +{ + my ($url, $dir, $pattern) = @_; + $dir = defined($dir) ? $dir : '.'; + + my $wget = "wget --retr-symlinks --passive-ftp --follow-ftp -Q 0 -N -nd -t 1 -P $dir"; + + my $cmd = defined($pattern) ? "$wget '$url/*' -A$pattern" : + "$wget '$url'"; + + `$cmd`; + + my $downloaded_file = undef; + + if($url =~ /\/([^\/]+) *$/) + { + $downloaded_file = $dir . '/' . $1; + } + + return $downloaded_file; +} + +sub downloadMultiple +{ + my ($url, $dir, $pattern) = @_; + $dir = defined($dir) ? $dir : '.'; + + my $wget = "wget --retr-symlinks --passive-ftp -Q 0 -N -nd -t 1 -P $dir"; + + my $cmd = "$wget $url"; + + `$cmd`; + + my $downloaded_file = undef; + + if($url =~ /\/([^\/]+) *$/) + { + $downloaded_file = $dir . '/' . $1; + } + + return $downloaded_file; +} + +sub copyFile +{ + my ($source, $destination) = @_; + + my $s = &openFile($source, "r"); + + my $d = &openFile($destination, "w"); + + (defined($s) and defined($d)) or die("Could not copy '$source' to '$destination'"); + + while(my $line = <$s>) + { + print $d $line; + } + + close($s); + + close($d); +} + +sub deleteFile +{ + my ($file) = @_; + + system("rm -f $file"); +} + +sub makeTmpFile +{ + my ($prefix, $file) = @_; + + $prefix = defined($prefix) ? $prefix : ''; + + my $suffix = '.tmp'; + + my $tmpname = ''; + + my $tmpfile = undef; + + my $maxtries = 1000000; + + for(my $i = 0; not(defined($tmpfile)) and ($i < $maxtries); $i++) + { + my $time = time; + + my $rand = int(rand(1000000)); + + $tmpname = $prefix . '_' . $time . '_' . $rand . $suffix; + + if(&pathExists($tmpname)) + { + $tmpfile = undef; + } + + else + { + if(defined($file)) + { + ©File($file, $tmpname); + } + return $tmpname; + } + } + + die("Could not open a temporary file"); + + return $tmpname; +} + +sub findLine +{ + my ($filep, $patterns, $logic) = @_; + + $logic = defined($logic) ? $logic : 'and'; + + my $result = undef; + + if(($logic =~ /and/i) or ($logic =~ /all/i)) + { + $result = &findLineWhereAllMatch($filep, $patterns); + } + + if(($logic =~ /or/i) or ($logic =~ /any/i)) + { + $result = &findLineWhereAnyMatch($filep, $patterns); + } + + return $result; +} + +sub findLineWhereAllMatch +{ + my ($filep, $patterns) = @_; + + while(my $line = <$filep>) + { + my $match = 1; + + foreach my $pattern (@{$patterns}) + { + if(not($line =~ /$pattern/)) + { + $match = 0; + } + } + + if($match) + { + return $line; + } + } + + return undef; +} + +sub findLineWhereAnyMatch +{ + my ($filep, $patterns) = @_; + + while(my $line = <$filep>) + { + my $match = 0; + + foreach my $pattern (@{$patterns}) + { + if($line =~ /$pattern/) + { + $match = 1; + } + } + + if($match) + { + return $line; + } + } + + return undef; +} + +sub printMatrix +{ + my ($matrix, $file, $delim_col, $delim_row) = @_; + + $file = defined($file) ? $file : \*STDOUT; + + $delim_col = defined($delim_col) ? $delim_col : "\t"; + + $delim_row = defined($delim_row) ? $delim_row : "\n"; + + my $n = scalar(@{$matrix}); + + for(my $i = 0; $i < $n; $i++) + { + print $file join($delim_col, @{$$matrix[$i]}), $delim_row; + } +} + +sub readIds +{ + my ($file, $column, $delim) = @_; + + $column = defined($column) ? $column : 0; + + $delim = defined($delim) ? $delim : "\t"; + + my $filep = &openFile($file); + + my $num_keys = 0; + + my %seen; + + my @ids; + + my @rows; + + my $row = 0; + + while(my $line = <$filep>) + { + my @tuple = split($delim, $line); + + if($column <= $#tuple) + { + my $key = $tuple[$column]; + + if(not(exists($seen{$key}))) + { + $ids[$num_keys] = $key; + + $rows[$num_keys] = [$row]; + + $seen{$key} = $num_keys; + + $num_keys++; + } + else + { + my $first_row = $seen{$key}; + + push(@{$rows[$first_row]}, $row); + } + } + + $row++; + } + + close($filep); + + return (\@ids, \@rows); +} + +sub readDataMatrix +{ + my ($file, $key_col, $delim, $max_cols) = @_; + + $file = defined($file) ? $file : $_; + + $key_col = defined($key_col) ? $key_col : 0; + + $delim = defined($delim) ? $delim : "\t"; + + my $filep = &openFile($file); + + my @data; + + if(defined($max_cols)) + { + $$max_cols = 0; + } + + while(my $line = <$filep>) + { + my @tuple = split($delim, $line); + + chomp($tuple[$#tuple]); + + my $key = splice(@tuple, $key_col, 1); + + unshift(@tuple, $key); + + push(@data, \@tuple); + + if(defined($max_cols) and scalar(@tuple) > $$max_cols) + { + $$max_cols = scalar(@tuple); + } + } + + close($filep); + + return \@data; +} + +sub getFilesFromList +{ + my ($args) = @_; + + my @files; + + foreach my $arg (@{$args}) + { + if((-f $arg) or (-l $arg)) + { + push(@files, $arg); + } + } + + return \@files; +} + +sub getColumn +{ + my ($file, $col, $delim, $blank) = @_; + + $file = defined($file) ? $file : $_; + + $col = defined($col) ? $col : 0; + + $delim = defined($delim) ? $delim : "\t"; + + my @list; + + my $filep = &openFile($file); + + while(my $line = <$filep>) + { + my @x = split($delim, $line); + + chomp($x[$#x]); + + my $val = $col < scalar(@x) ? $x[$col] : + (defined($blank) ? $blank : undef); + + if(defined($val)) + { + push(@list, $val); + } + } + + close($filep); + + return \@list; +} + + +##-------------------------------------------------------------------------------------- +## ExtractFileLinesBetweenRegexps +##-------------------------------------------------------------------------------------- +sub ExtractFileLinesBetweenRegexps +{ + my ($in_file_ref, $out_file_ref, $regexp_from, $regexp_to, $from_inclusive, $to_inclusive) = @_; + + if ( $regexp_from eq $regexp_to ) { + die "(/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl) ExtractFileLinesBetweenRegexps() - 'from' and 'to' regexps are identical. Give me a break, use grep.\n"; + } + + my $reached_from = 0; + if ( $regexp_from eq "" ) { + $reached_from = 1; + } + + while (<$in_file_ref>) { + chomp; + + if ( $reached_from == 0 ) { + if ( $_ =~ /$regexp_from/ ) { + $reached_from = 1; + next unless ( $from_inclusive ); + } + } + + if ( $reached_from == 1 ) { + if ( $regexp_to ne "" and $_ =~ /$regexp_to/ ) { + print $out_file_ref "$_\n" if ( $to_inclusive ); + last; # break from while loop, and end. + } + else { + print $out_file_ref "$_\n"; + } + } + } +} + + +##-------------------------------------------------------------------------------------- +## ExtractAllFileLinesNotBetweenRegexps +##-------------------------------------------------------------------------------------- +sub ExtractAllFileLinesNotBetweenRegexps +{ + my ($in_file_ref, $out_file_ref, $regexp_from, $regexp_to, $from_inclusive, $to_inclusive) = @_; + + if ( $regexp_from eq $regexp_to ) { + die "(/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl) ExtractAllFileLinesNotBetweenRegexps() - 'from' and 'to' regexps are identical. Give me a break, use grep.\n"; + } + + my $print_flag = 1; + if ( $regexp_from eq "" ) { + $print_flag = 0; + } + + while (<$in_file_ref>) { + chomp; + + if ( $print_flag == 1 ) { + if ( $_ =~ /$regexp_from/ ) { + $print_flag = 0; + next unless ( $from_inclusive ); + } + print $out_file_ref "$_\n"; + } + + if ( $print_flag == 0 ) { + last if ( $regexp_to eq "" ); # break from while loop, and end. + + if ( $_ =~ /$regexp_to/ ) { + $print_flag = 1; + print $out_file_ref "$_\n" if ( $to_inclusive ); + } + } + } +} + + +##-------------------------------------------------------------------------------------- +## ReplaceStringInFile +##-------------------------------------------------------------------------------------- +sub ReplaceStringInFile +{ + my ($in_file_ref, $out_file_ref, $to_replace, $replace_with) = @_; + + while (<$in_file_ref>) { + chomp; + $_ =~ s/$to_replace/$replace_with/g; + print $out_file_ref "$_\n"; + } +} + +1 diff --git a/modules/local/pita/templates/lib/libstats.pl b/modules/local/pita/templates/lib/libstats.pl new file mode 100755 index 00000000..92f24422 --- /dev/null +++ b/modules/local/pita/templates/lib/libstats.pl @@ -0,0 +1,816 @@ +#!/usr/bin/perl + +use strict; +use POSIX; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/ltqnorm.pl"; + +my $MAXDOUBLE = 1e200; + +my $LOG10 = log(10); + +my $PI = 3.141592654; + +my $MIN_NUMBER_TO_EXPONENTIATE = -100; + +#print ComputeHyperPValue($ARGV[0], $ARGV[1], $ARGV[2], $ARGV[3]) . "\n"; +#print NormalStd2Pvalue($ARGV[0]); + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeBinomial +{ + my ($p, $n, $r) = @_; + + my $binom = -$MAXDOUBLE; + my $x=1; + for (my $i = $r; $i <= $n; $i++) + { + $binom = &AddLog($binom, lchoose($i, $n) + $i * log($p) + ($n - $i) * log(1-$p)); + } + + return exp($binom); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeBinomial2 +{ + my ($p, $n, $r) = @_; + + my $binom = -$MAXDOUBLE; + my $x=1; + for (my $i = $r; $i <= $n; $i++) + { + $binom = &AddLog($binom, lchoose_Stanica($i, $n) + $i * log($p) + ($n - $i) * log(1-$p)); + } + + return exp($binom); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Log +{ + my ($x) = @_; + + if ($x == 0.0) + { + return -$MAXDOUBLE; + } + else + { + return log($x); + } +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeTTest +{ + my ($x, $dof) = @_; + + my $u = $dof / ($dof + $x * $x); + + my $val = 0.5 * &BetaCDF($u, 0.5 * $dof, 0.5); + + return $x > 0 ? 1 - $val : $val; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeTValue +{ + my ($n1, $m1, $s1, $n2, $m2, $s2) = @_; + + my $se = sqrt ((($s1 * $s1) / $n1) + (($s2 * $s2) / $n2)); + + my $val = ($m1 - $m2) / $se; + + return $val < 0 ? $val : -$val; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub BetaCDF +{ + my ($x, $a, $b) = @_; + + my $bt; + + if ($x == 0 or $x == 1) { $bt = 0; } + else + { + $bt = exp(&lgamma($a + $b) - &lgamma($a) - &lgamma($b) + $a * log($x) + $b * log(1 - $x)); + } + + return $x < (($a + 1) / ($a + $b + 2)) ? return ($bt * &BetaCF($x, $a, $b) / $a) : 1 - ($bt * &BetaCF(1 - $x, $a, $b) / $b) +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub BetaCF +{ + my ($x, $a, $b) = @_; + + my $maxit = 100; + + my $eps = 0.0000003; + my $am = 1; + my $bm = 1; + my $az = 1; + my $qab = $a + $b; + my $qap = $a + 1; + my $qam = $a - 1; + my $bz = 1 - $qab * $x / $qap; + my $tem; + my $em; + my $d; + my $bpp; + my $bp; + my $app; + my $aOld; + my $ap; + + for (my $m = 1; $m <= $maxit; $m++) + { + $em = $m; + $tem = $em + $em; + $d = $em * ($b - $m) * $x / (($qam + $tem) * ($a + $tem)); + $ap = $az + $d * $am; + $bp = $bz + $d * $bm; + $d = -($a + $em) *($qab + $em) * $x / (($a + $tem) * ($qap + $tem)); + $app = $ap + $d * $az; + $bpp = $bp + $d * $bz; + $aOld = $az; + $am = $ap / $bpp; + $bm = $bp / $bpp; + $az = $app / $bpp; + $bz = 1; + if (&Abs($az - $aOld) < $eps * &Abs($az)) + { + last; + } + } + + return $az; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Abs +{ + my ($x) = @_; + + return $x > 0 ? $x : -$x; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeLog10HyperPValue +{ + my ($k, $n, $K, $N) = @_; + + my $p = $K / $N; + + if ($k < $p * $n) + { + return 0; + } + + + if ($N == 0 or $n == 0 or ($k > $n) or ($K > $N)) + { + return undef; + } + + my $pvalue = &lchoose($k, $K) + &lchoose($n - $k, $N - $K) - &lchoose($n, $N); + + return $pvalue / $LOG10; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeHyperPValue +{ + my ($k, $n, $K, $N) = @_; + + my $p = $K / $N; + + my $d = ($k < $p * $n) ? -1 : +1; + + my $PVal = 0; + + if ($d == 1) + { + $PVal = -$MAXDOUBLE; + + for (; $k >= 0 and $k <= $n and $k <= $K ; $k += $d) + { + my $x = &lchoose($k, $K) + &lchoose($n - $k, $N - $K) - &lchoose($n, $N); + +# my $x = &log_bincoef_approx($k, $K) + &log_bincoef_approx($n - $k, $N - $K) - &log_bincoef_approx($n, $N); + + $PVal = &AddLog($PVal, $x); + } + } + + return exp($PVal); +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeHyperPValue2 +{ + my ($k, $n, $K, $N) = @_; + my $p = $K / $N; + my $d = ($k < $p * $n) ? -1 : +1; + my $PVal = 0; + if ($d == 1) + { + $PVal = -$MAXDOUBLE; + for (; $k >= 0 and $k<=$n and $k<=$K; $k += $d) + { + my $x = &lchoose_Stanica($k, $K) + &lchoose_Stanica($n - $k, $N - $K) - &lchoose_Stanica($n, $N); + $PVal = &AddLog($PVal, $x); + } + } + return exp($PVal); +} + +# bound formulas taken from "Good lower and upper bounds on binomial coefficients" JIPAM (2001) by Stanica +sub lchoose_Stanica{ + my $n=shift; + my $k=shift; + return (lchoose_Stanica_upperb($n,$k)+lchoose_Stanica_lowerb($n,$k))/2; +} + +#upper bound +sub lchoose_Stanica_upperb{ + my $n=shift; + my $k=shift; + if ($k==$n or $n==0){return 0}; + my $m=$k/$n; + return log(1/sqrt(2*(4*atan2(1,1))))-0.5*log($n)+($m*$n+0.5)*log($m)-(($m-1)*$n+0.5)*log($m-1)-($n+0.5)*log(1) ; +} + +#lower bound +sub lchoose_Stanica_lowerb{ + my $n=shift; + my $k=shift; + if ($k==$n or $n==0){return 0}; + my $m=$k/$n; + return log(1/sqrt(2*(4*atan2(1,1))))+1-1/(8*$n)-0.5*log($n)+($m*($n-1)+1)*log($m)-($m-1)*($n-1)*log($m-1)-($n+0.5)*log(1) ; +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub log_bincoef_approx + { + my ($k,$n); + + my $MY_PI = 4 * atan2(1, 1); + + if ($k==$n or $k==0){ + return 0; + } + + my $m = $n/$k; + + my $const = (1 / sqrt(2 * $MY_PI)); + + return log($const) + log($k)*(-0.5) + log($m)*($m*($k-1)+1) - log($m-1)*($m-1)*($k-1); + +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub log10 { + my $n = shift; + return log($n)/log(10); +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeHyperPValueOneTailed +{ + my ($k, $n, $K, $N) = @_; + + my $p = $K / $N; + + my $d = ($k < $p * $n) ? -1 : +1; + + my $PVal = 0; + + if ($d == 1) + { + $PVal = -$MAXDOUBLE; + + for (; $k >= 0 and $k <= $n; $k += $d) + { + my $x = &lchoose($k, $K) + &lchoose($n - $k, $N - $K) - &lchoose($n, $N); + + $PVal = &AddLog($PVal, $x); + } + } + + return exp($PVal); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeWilcoxonSumRankTest +{ + my ($m, $n, $w) = @_; + + # m = number of items in sample 1 + # n = number of items in sample 2 + # w = sum of the ranks in sample 2 + + my $mean = $n * ($m + $n + 1) / 2; + my $std = sqrt($m * $n * ($m + $n + 1) / 12); + + my $num_std = abs(($w - $mean) / $std); + + #print "m=$m n=$n w=$w $mean\t$std\t$num_std\n"; + + return &NormalStd2Pvalue($num_std); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeMannWhitneyUTest +{ + my ($n1, $n2, $r1) = @_; + + my $U = $n1*$n2 + ($n1*($n1+1)/2) - $r1; + return ($U / ($n1*$n2)); +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ComputeWilcoxonSumRankTestOneTailed +{ + my ($m, $n, $w) = @_; + + # m = number of items in sample 1 + # n = number of items in sample 2 + # w = sum of the ranks in sample 2 + # + # Checking hypothesis that sample 1 has sum of ranks lower than + # sample 2. + + my $mean = $n * ($m + $n + 1) / 2; + my $std = sqrt($m * $n * ($m + $n + 1) / 12); + + my $num_std = abs(($w - $mean) / $std); + + #print "m=$m n=$n w=$w $mean\t$std\t$num_std\n"; + + my $twoTailed = &NormalStd2Pvalue($num_std); + + return ($w > $mean ? $twoTailed : (1-$twoTailed)); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub lchoose +{ + my ($k, $N) = @_; + + return $k > $N ? 0 : &lgamma($N + 1) - &lgamma($k + 1) - &lgamma($N - $k + 1); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub AddLog +{ + my ($x, $y) = @_; + + if ($x == -$MAXDOUBLE) { return $y }; + if ($y == -$MAXDOUBLE) { return $x }; + if ($x >= $y) + { + $y -= $x; + } + else + { + my $t = $x; + $x = $y; + $y = $t - $x; + } + + return $x + log(1 + exp($y)); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub lgamma +{ + # per code from numerical recipies + my $xx = $_[0]; + + my ($j, $ser, $stp, $tmp, $x, $y); + my @cof = (0.0, 76.18009172947146, -86.50532032941677, 24.01409824083091, -1.231739572450155, 0.1208650973866179e-2, -0.5395239384953e-5); + my $stp = 2.5066282746310005; + + $x = $xx; + $y = $x; + $tmp = $x + 5.5; + $tmp = ($x+0.5)*log($tmp)-$tmp; + $ser = 1.000000000190015; + foreach $j ( 1 .. 6 ) + { + $y+=1.0; + $ser+=$cof[$j]/$y; + } + return $tmp + log($stp*$ser/$x); +} + +#----------------------------------------------------------------------------- +# $double ComputeSymmetricUniformCdf(\@list reals, $int already_sorted=0) +#----------------------------------------------------------------------------- +sub ComputeSymmetricUniformCdf +{ + my ($reals, $already_sorted) = @_; + $already_sorted = defined($already_sorted) ? $already_sorted : 0; + + my $list; + if(not($already_sorted)) + { + my @list = sort {$b <=> $a} @{$reals}; + push(@list, 0.0); + $list = \@list; + } + else + { + $list = $reals; + } + + if(scalar(@{$list}) == 1) + { + return 1.0; + } + else + { + my $cummulative_probability = 0.0; + + for(my $i = 0; $i < scalar(@{$list}) - 1; $i++) + { + my $range = $$list[$i] - $$list[$i + 1]; + + my @list = @{$list}; + + splice(@list, $i, 1); + + $cummulative_probability += $range * &ComputeSymmetricUniformCdf(\@list, 1); + } + + return $cummulative_probability; + } +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Pearson2FisherZ +{ + my ($r) = @_; + + my $z = defined($r) ? 0.5 * (log(1 + $r) - log(1 - $r)) : undef; + + return $z; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Pearson2FisherZscore +{ + my ($r, $dimensions) = @_; + + my $z = &Pearson2FisherZ($r); + my $zscore = (defined($z) and $dimensions > 3) ? $z * sqrt($dimensions - 3) : undef; + + return $zscore; +} + +my $TWICE_A = 1.7155277699214135; + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub sample_normal +{ + while (1) + { + my $u = rand(); + if ($u != 0.0) + { + my $v = (rand() - 0.5) * $TWICE_A; + my $x = $v / $u; + my $sqr_x = $x*$x; + if ($sqr_x <= 6 - 8*$u + 2*$u*$u) + { + return $x; + } + if (!($sqr_x >= 2 / $u - 2 * $u)) + { + if ($sqr_x <= -4 * log($u)) + { + return $x; + } + } + } + } +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub sample_normal_general +{ + my ($mean, $std) = @_; + + my $normal = &sample_normal(); + + return ($std * $normal) + $mean; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub compute_normal_general +{ + my ($normal, $mean, $std) = @_; + + return (1 / (sqrt(2 * $PI) * $std)) * exp(-($normal - $mean) * ($normal - $mean) / (2 * $std * $std)); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub compute_log_normal_general +{ + my ($normal, $mean, $std) = @_; + + my $prob = &compute_normal_general($normal, $mean, $std); + + return $prob == 0 ? -$MAXDOUBLE : log($prob); +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub NormalStd2Pvalue +{ + my ($std) = @_; + + my $max = 1; + my $min = 0; + my $res = ($min + $max) / 2; + + while ($max - $min > 0.000000000000001) + { + my $qnorm = <qnorm($res); + + if ($qnorm < $std) + { + $min = $res; + } + else + { + $max = $res; + } + + $res = ($max + $min) / 2; + } + + return 1 - $res; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub IntersectNormals +{ + my ($mean1, $var1, $mean2, $var2, $lower_solution) = @_; + + my $a = $var1 - $var2; + my $b = 2 * $mean1 * $var2 - 2 * $mean2 * $var1; + my $c = $mean2 * $mean2 * $var1 - $mean1 * $mean1 * $var2 + $var1 * $var2 * 0.5 * log($var2 / $var1); + + my $res = 0; + + if ($a == 0) + { + $res = -$c / $b; + } + else + { + my $solution1 = (-$b + sqrt($b * $b - 4 * $a * $c)) / (2 * $a); + my $solution2 = (-$b - sqrt($b * $b - 4 * $a * $c)) / (2 * $a); + + $res = $lower_solution == 1 ? &Min($solution1, $solution2) : &Max($solution1, $solution2); + } + + return $res; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Min +{ + my ($num1, $num2) = @_; + + return $num1 < $num2 ? $num1 : $num2; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Max +{ + my ($num1, $num2) = @_; + + return $num1 > $num2 ? $num1 : $num2; +} + +#----------------------------------------------------------------------------- +# compute log(exp(a_1)+exp(a_2)+...exp(a_n)) using: +# max(a_1,a_2,..a_n) + log(1+exp(a_2-max(a_1,a_2,..a_n))+...exp(a_n-max(a_1,a_2,..a_n))) +#----------------------------------------------------------------------------- +sub LogOfSumOfExps +{ + my ($ref_exps) = @_; + + my @exps = @$ref_exps; + my $num_exps = scalar(@exps); + my $max_index = 0; + my $max = $exps[0]; + my $i = 0; + + for ($i=1; $i<$num_exps; $i++) + { + if ($exps[$i] > $max) + { + $max = $exps[$i]; + $max_index = $i; + } + } + + my $remaining_summand = 1.0; + + for ($i = 0; $i < $num_exps; $i++) + { + if ($i != $max_index) + { + my $difference = $exps[$i] - $max; + if ($difference > $MIN_NUMBER_TO_EXPONENTIATE){ + $remaining_summand += exp($difference); + } + } + } + + my $result = $max + log($remaining_summand); + + return $result; +} + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub KolmogorovSmirnovProbability +{ + my ($size1, $size2, $res_d_statistic) = @_; + + my $dtmp1 = sqrt(($size1 * $size2)/($size1 + $size2)); + + my $x = ($dtmp1 + 0.12 + 0.11 / $dtmp1) * $res_d_statistic; + + my $x2 = -2.0 * $x * $x; + my $eps1 = 10 * DBL_EPSILON; + my $eps2 = DBL_EPSILON; + + my $i = 1; + my $fac = 2.0; + my $sum = 0.0; + my $term = 0.0; + my $absterm = 0.0; + + do + { + $absterm = abs($term); + $term = $fac * exp($x2 * $i * $i); + $sum += $term; + $fac = -1 * $fac; + $i++; + } + while (abs($term) > $eps1 * $absterm && abs($term) > $eps2 * $sum); + + return $sum; + +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ArrayRefMean { + my $array_ref = shift; + my $num_elements = scalar @$array_ref; + my $sum = 0; + + foreach (@$array_ref) { + $sum += $_; + } + return $sum / $num_elements; +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub ArrayRefStd { + my $array_ref = shift; + my $num_elements = scalar @$array_ref; + my $sum = 0; + my $sumsq = 0; + + foreach (@$array_ref) { + $sum += $_; + $sumsq += ($_ **2); + } + return sqrt( $sumsq/$num_elements - + (($sum/$num_elements) ** 2)); +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Bonferroni { + my ($alpha,$num_pvalues) = @_; + if ( $num_pvalues == 0 ) { return $alpha; } + return $alpha/$num_pvalues; +} + + +#----------------------------------------------------------------------------- +# +#----------------------------------------------------------------------------- +sub Fdr { + my ($alpha,$num_pvalues,$pvalues_ref) = @_; + if ( $num_pvalues == 0 ) { return 0; } + + my @sorted_pvalues = sort { $a <=> $b } @$pvalues_ref; + + for ( my $i = $num_pvalues-1 ; $i >= 0 ; $i-- ) { + my $randomly_expected = $sorted_pvalues[$i] * $num_pvalues; + my $current_pvalue = $randomly_expected / ($i+1); + if ( $current_pvalue <= $alpha ) { return $sorted_pvalues[$i]; } + } + return 0; +} + + + +#print NormalStd2Pvalue($ARGV[0]) . "\n"; +#print ComputeWilcoxonSumRankTest($ARGV[0], $ARGV[1], $ARGV[2]) . "\n"; +#print ComputeBinomial($ARGV[0], $ARGV[1], $ARGV[2]) . "\n"; +#print ComputeHyperPValue($ARGV[0], $ARGV[1], $ARGV[2], $ARGV[3]) . "\n"; #(k, n, K, N) +#print ComputeLog10HyperPValue($ARGV[0], $ARGV[1], $ARGV[2], $ARGV[3]) . "\n"; #(k, n, K, N) +#print &ComputeTTest($ARGV[0], $ARGV[1]) . "\n"; +#print &compute_normal_general($ARGV[0], $ARGV[1], $ARGV[2]) . "\n"; +#print &compute_log_normal_general($ARGV[0], $ARGV[1], $ARGV[2]) . "\n"; +#print &IntersectNormals(0, 1, 2, 4, 1); +#print "\n"; +#for(my$i=0;$i<=256;$i++){print "$i\t" . chr($i) . "A\n";} + +1 + diff --git a/modules/local/pita/templates/lib/libtable.pl b/modules/local/pita/templates/lib/libtable.pl new file mode 100755 index 00000000..9364ce9f --- /dev/null +++ b/modules/local/pita/templates/lib/libtable.pl @@ -0,0 +1,288 @@ +use strict; + +#------------------------------------------------------------------------ +# $int getNumCols($string file, $string delim="\t") +#------------------------------------------------------------------------ +sub getNumCols +{ + my ($file, $delim) = @_; + $delim = not(defined($delim)) ? "\t" : $delim; + my $fp; + open($fp, $file) or die("Could not open file '$file'"); + my $done = 0; + my $num_cols = undef; + while(not(defined($num_cols)) and not(eof($fp))) + { + my $line = <$fp>; + if($line =~ /\S/) + { + my @tuple = split($delim, $line); + $num_cols = scalar(@tuple); + # print STDERR "$num_cols : ", join("-", @tuple), "'\n"; + } + } + return $num_cols; +} + +#------------------------------------------------------------------------ +# ($string, \@list) splitKeyAndValue ($string line, \@list key_cols, +# \@list sorted_key_cols, $string delim) +#------------------------------------------------------------------------ +sub splitKeyAndValue +{ + my ($line,$key_cols,$sorted_key_cols,$delim) = @_; + $sorted_key_cols = defined($sorted_key_cols) ? $sorted_key_cols : $key_cols; + $delim = defined($delim) ? $delim : "\t"; + my @tuple = split($delim, $line); + my @tuple_copy = @tuple; + + if($#tuple == -1) + { return (undef,undef); } + + chomp($tuple[$#tuple]); + chomp($tuple_copy[$#tuple]); + + # Remove key entries from the tuple in reverse order to + # preserve the indexing. + my @key; + my $j=0; + for(my $i=scalar(@{$sorted_key_cols})-1; $i>=0; $i--) + { + $j++; + push(@key, $tuple_copy[$$key_cols[$j]]); + splice(@tuple,$$sorted_key_cols[$i], 1); + } + return (join($delim,@key),\@tuple); +} + +#--------------------------------------------------------------------------- +# \@list listRead ($string file, $string delim="\t", \@list key_cols=(1)) +#--------------------------------------------------------------------------- +sub tableRead +{ + my ($file, $delim, $key_cols) = @_; + $delim = not(defined($delim)) ? "\t" : $delim; + if(not(defined($key_cols))) + { + my @key_cols = (1); + $key_cols = \@key_cols; + } + my @sorted_key_cols = sort { $a <=> $b; } @{$key_cols}; + my $filep; + open($filep, $file) or die("Could not open file '$file'"); + my @tuples; + while(<$filep>) + { + chomp; + my $line = $_; + my ($key, $tuple) = &splitKeyAndValue($line, $key_cols, \@sorted_key_cols, $delim); + my @key_tuple = ($key); + push(@key_tuple, @{$tuple}); + push(@tuples, \@key_tuple); + } + close($filep); + + return \@tuples; +} + +#------------------------------------------------------------------------ +# \@list emptyTuple ($int n) +#------------------------------------------------------------------------ +sub emptyTuple +{ + my $n = shift; + my @blanks = (); + + for(my $i=0; $i<$n; $i++) + { push(@blanks,''); } + + return \@blanks; +} + +#------------------------------------------------------------------------ +# $int getTupleLength ($string line, $string delim) +#------------------------------------------------------------------------ +sub getTupleLength +{ + my ($line, $delim) = @_; + $line = defined($line) ? $line : $_; + $delim = defined($delim) ? $delim : "\t"; + + my @tuple = split($delim, $line); + return ($#tuple + 1); +} + +#------------------------------------------------------------------------ +# $int compareKeys ($string key1, $string key2) +#------------------------------------------------------------------------ +sub compareKeys +{ + my ($key1, $key2) = @_; + + if(not(defined($key1)) or length($key1)==0) + { return 1; } + + if(not(defined($key2)) or length($key2)==0) + { return -1; } + + return($key1 cmp $key2); +} + +#------------------------------------------------------------------------ +# $string getSubTupleString ($string line, \@list cols, $string delim) +#------------------------------------------------------------------------ +sub getSubTupleString +{ + my ($line,$cols,$delim) = @_; + $delim = defined($delim) ? $delim : "\t"; + my @tuple = split($delim, $line); + + if($#tuple==-1 or scalar(@{$cols})<=0) + { return undef; } + + chomp($tuple[$#tuple]); + + my $sub = $tuple[$$cols[0]]; + for(my $i=1; $i $precision) + { $precision = $num; } + } + return $precision; +} + +#------------------------------------------------------------------------ +# (\@list lines, $string last_line) +# getLinesWithIdenticalKeys ($fp file, \@list key_cols, +# $string last_line, string $delim) +#------------------------------------------------------------------------ +sub getLinesWithIdenticalKeys +{ + my ($file,$key_cols,$last_line,$delim) = @_; + my $key = undef; + my $first_key = undef; + my @lines = (); + my $done = 0; + + if(eof($file)) + { + @lines = ($last_line); + return (\@lines,undef); + } + + while(not($done)) + { + my $line = defined($last_line) ? $last_line : <$file>; + $last_line = undef; + $key = &getSubTupleString($line,$key_cols,$delim); + $first_key = defined($first_key) ? $first_key : $key; + my $order = &compareKeys($key,$first_key); + if($order == 0) + { push(@lines, $line); } + else + { + $done = 1; + $last_line = $line; + } + + if(eof($file)) + { $done = 1; } + } + return (\@lines,$last_line); +} + +##------------------------------------------------------------------------ +## void sequentialJoin ($string out_file, @list in_files) +##------------------------------------------------------------------------ +sub sequentialJoin +{ + my ($out_file, @in_files) = @_; + my $in_file = $in_files[0]; + my $join = "cat $in_file "; + for(my $i = 1; $i <= $#in_files; $i++) + { + my $in_file = $in_files[$i]; + $join .= "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/join.pl -q - $in_file "; + } + $join .= "> $out_file"; + + print STDERR "--> $join <--\n"; + `$join`; + print STDERR "--> Done. <--\n"; +} + + +1 diff --git a/modules/local/pita/templates/lib/lin.pl b/modules/local/pita/templates/lib/lin.pl new file mode 100755 index 00000000..d1633ac0 --- /dev/null +++ b/modules/local/pita/templates/lib/lin.pl @@ -0,0 +1,48 @@ +#!/usr/bin/perl + +use strict; + +my $arg=''; +my $delim="\t"; +my $i=1; +my $after=0; +my $neg = ''; +my $inc=1; + +while(@ARGV) + { + $arg = shift @ARGV; + if($arg =~ /-([-]*\d+)/) + { + # Start counting from the number they pass in: + $i=int($1); + } + elsif($arg eq '-d') + { + $delim = shift @ARGV; + } + elsif($arg eq '-a') + { + $after=1; + } + elsif($arg eq '-n') + { + $neg = '-'; + } + elsif($arg eq '-i') + { + $inc = shift @ARGV; + } + } + +# Add line numbers to the file. +while() + { + chop; + if(not($after)) + { print STDOUT $neg, "$i", $delim, "$_\n"; } + else + { print STDOUT "$_", $delim, $neg, "$i\n"; } + + $i += $inc; + } diff --git a/modules/local/pita/templates/lib/load_args.pl b/modules/local/pita/templates/lib/load_args.pl new file mode 100755 index 00000000..a379713c --- /dev/null +++ b/modules/local/pita/templates/lib/load_args.pl @@ -0,0 +1,142 @@ +#!/usr/bin/perl + +#--------------------------------------------------------- +# load_args +#--------------------------------------------------------- +sub load_args (\@) +{ + my @args = @{@_[0]}; + + my %result; + + my $num_args = @args; + + for (my $current_arg = 0; $current_arg < $num_args; $current_arg++) + { + my $arg = $args[$current_arg]; + + if ($arg =~ /-([^\s]+)/) + { + my $arg_name = $1; + + my $next_arg = $args[$current_arg + 1]; + + if ($next_arg =~ /^-([^\s])/ || length($next_arg) == 0) + { + $result{$arg_name} = "1"; + } + else + { + $next_arg =~ s/[\']//g; + $next_arg =~ s/[\"]//g; + + $result{$arg_name} = $next_arg; + $current_arg++; + } + + #print "load_args: result{$arg_name}=$result{$arg_name}\n"; + } + } + + return %result; +} + +#--------------------------------------------------------- +# get_arg +#--------------------------------------------------------- +sub get_arg ($$\%) +{ + my ($arg, $default, $str_args) = @_; + my %args = %$str_args; + + if (length($args{$arg}) > 0) { return $args{$arg}; } + else { return $default; } +} + +#--------------------------------------------------------- +# echo_arg +#--------------------------------------------------------- +sub echo_arg ($$\%) +{ + my ($arg, $str_args) = @_; + my %args = %$str_args; + + if (length($args{$arg}) > 0) { return "-$arg $args{$arg} "; } + else { return ""; } +} + +sub echo_arg_quoted ($$\%) +{ + my ($arg, $str_args) = @_; + my %args = %$str_args; + + if (length($args{$arg}) > 0) { return "-$arg \"$args{$arg}\" "; } + else { return ""; } +} +#--------------------------------------------------------- +# echo_arg_equals +#--------------------------------------------------------- +sub echo_arg_equals ($$\%) +{ + my ($arg, $str_args) = @_; + my %args = %$str_args; + + if (length($args{$arg}) > 0) { return "$arg" . "=" ."\"$args{$arg}\" "; } + else { return ""; } +} +#--------------------------------------------------------- +# get_extended_arg +#--------------------------------------------------------- +sub get_extended_arg ($\%) +{ + my ($arg, $str_args) = @_; + my %args = %$str_args; + + my @res; + my $id = 1; + my $done = 0; + while ($done == 0) + { + my $extended_arg = &get_arg("$arg$id", "", \%args); + if (length($extended_arg) > 0) + { + push(@res, $extended_arg); + + $id++; + } + else + { + $done = 1; + } + } + + return @res; +} + +#--------------------------------------------------------- +# get_full_arg_command +#--------------------------------------------------------- +sub get_full_arg_command (\@) +{ + my @args = @{@_[0]}; + + my $res = ""; + + for (my $current_arg = 0; $current_arg < @args; $current_arg++) + { + my $arg = $args[$current_arg]; + + if ($arg =~ /-([^\s]+)/) + { + $res .= "$arg "; + } + else + { + $res .= "'$arg' "; + } + } + + return $res; +} + +1 diff --git a/modules/local/pita/templates/lib/ltqnorm.pl b/modules/local/pita/templates/lib/ltqnorm.pl new file mode 100755 index 00000000..ddf749ad --- /dev/null +++ b/modules/local/pita/templates/lib/ltqnorm.pl @@ -0,0 +1,70 @@ +#!/usr/bin/perl + +sub ltqnorm ($) { + # + # Lower tail quantile for standard normal distribution function. + # + # This function returns an approximation of the inverse cumulative + # standard normal distribution function. I.e., given P, it returns + # an approximation to the X satisfying P = Pr{Z <= X} where Z is a + # random variable from the standard normal distribution. + # + # The algorithm uses a minimax approximation by rational functions + # and the result has a relative error whose absolute value is less + # than 1.15e-9. + # + # Author: Peter J. Acklam + # Time-stamp: 2000-07-19 18:26:14 + # E-mail: pjacklam@online.no + # WWW URL: http://home.online.no/~pjacklam + + my $p = shift; + die "input argument must be in (0,1)\n" unless 0 < $p && $p < 1; + + # Coefficients in rational approximations. + my @a = (-3.969683028665376e+01, 2.209460984245205e+02, + -2.759285104469687e+02, 1.383577518672690e+02, + -3.066479806614716e+01, 2.506628277459239e+00); + my @b = (-5.447609879822406e+01, 1.615858368580409e+02, + -1.556989798598866e+02, 6.680131188771972e+01, + -1.328068155288572e+01 ); + my @c = (-7.784894002430293e-03, -3.223964580411365e-01, + -2.400758277161838e+00, -2.549732539343734e+00, + 4.374664141464968e+00, 2.938163982698783e+00); + my @d = ( 7.784695709041462e-03, 3.224671290700398e-01, + 2.445134137142996e+00, 3.754408661907416e+00); + + # Define break-points. + my $plow = 0.02425; + my $phigh = 1 - $plow; + + # Rational approximation for lower region: + if ( $p < $plow ) { + my $q = sqrt(-2*log($p)); + return ((((($c[0]*$q+$c[1])*$q+$c[2])*$q+$c[3])*$q+$c[4])*$q+$c[5]) / + (((($d[0]*$q+$d[1])*$q+$d[2])*$q+$d[3])*$q+1); + } + + # Rational approximation for upper region: + if ( $phigh < $p ) { + my $q = sqrt(-2*log(1-$p)); + return -((((($c[0]*$q+$c[1])*$q+$c[2])*$q+$c[3])*$q+$c[4])*$q+$c[5]) / + (((($d[0]*$q+$d[1])*$q+$d[2])*$q+$d[3])*$q+1); + } + + # Rational approximation for central region: + my $q = $p - 0.5; + my $r = $q*$q; + return ((((($a[0]*$r+$a[1])*$r+$a[2])*$r+$a[3])*$r+$a[4])*$r+$a[5])*$q / + ((((($b[0]*$r+$b[1])*$r+$b[2])*$r+$b[3])*$r+$b[4])*$r+1); +} + +sub normalprob +{ + +} + +#print ltqnorm($ARGV[0]) . "\n"; + +1 + diff --git a/modules/local/pita/templates/lib/merge_columns.pl b/modules/local/pita/templates/lib/merge_columns.pl new file mode 100755 index 00000000..b65f3b0c --- /dev/null +++ b/modules/local/pita/templates/lib/merge_columns.pl @@ -0,0 +1,94 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $column_1 = get_arg("1", 0, \%args); +my $column_2 = get_arg("2", 1, \%args); +my $delimiter = get_arg("d", "", \%args); +my $reverse = get_arg("r", 0, \%args); +my $sort_by_strings = get_arg("s", 0, \%args); +my $sort_by_numbers = get_arg("sn", 0, \%args); +my $unique_merge = get_arg("u", 0, \%args); + +while (<$file_ref>) +{ + chop; + + my @row = split(/\t/); + + my $first = 1; + for (my $i = 0; $i < @row; $i++) + { + if ($i == $column_1) + { + if ($first == 1) { $first = 0; } else { print "\t"; } + + if ($unique_merge == 1 and $row[$column_2] eq $row[$column_1]) + { + print "$row[$column_1]"; + } + elsif ($reverse == 1) + { + print "$row[$column_2]$delimiter$row[$column_1]"; + } + elsif ($sort_by_strings == 1) + { + if ($row[$column_1] lt $row[$column_2]) { print "$row[$column_1]$delimiter$row[$column_2]"; } else { print "$row[$column_2]$delimiter$row[$column_1]"; } + } + elsif ($sort_by_numbers == 1) + { + if ($row[$column_1] < $row[$column_2]) { print "$row[$column_1]$delimiter$row[$column_2]"; } else { print "$row[$column_2]$delimiter$row[$column_1]"; } + } + else + { + print "$row[$column_1]$delimiter$row[$column_2]"; + } + } + elsif ($i != $column_2) + { + if ($first == 1) { $first = 0; } else { print "\t"; } + + print "$row[$i]"; + } + } + + print "\n"; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/merge_columns.pl + + Merges 2 columns with a specified delimiter + + -1 First column (default: 0) + -2 Second column (default: 1) + -d Delimiter (default: "") + -r Reverse: column 2 goes before column 1 + -s: Print the merged columns in sorted order (sort: by strings) + -sn: Print the merged columns in sorted order (sort: by numbers) + -u: If the two columns to be merged are identical, print only one item in the resulting column + diff --git a/modules/local/pita/templates/lib/modify_column.pl b/modules/local/pita/templates/lib/modify_column.pl new file mode 100755 index 00000000..4b09b369 --- /dev/null +++ b/modules/local/pita/templates/lib/modify_column.pl @@ -0,0 +1,568 @@ +#!/usr/bin/perl + +use strict; +use Scalar::Util qw(looks_like_number); +use POSIX qw(floor ceil); + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/format_number.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; + + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $LOG10 = log(10); +my $LOG2 = log(2); + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $columns = get_arg("c", 0, \%args); +my $rows = get_arg("r", "All", \%args); +my $apply_to_all_columns = get_arg("A", 0, \%args); +my $min_filter = get_arg("min", "None", \%args); +my $max_filter = get_arg("max", "None", \%args); +my $mins_filter = get_arg("mins", "None", \%args); +my $maxs_filter = get_arg("maxs", "None", \%args); +my $abs_filter = get_arg("abs", "None", \%args); +my $below_abs_filter = get_arg("babs", "None", \%args); +my $str_filter = get_arg("str", "None", \%args); +my $equal_str_filter = get_arg("estr", "None", \%args); +my $equal_str_list_filter_str = get_arg("estr_list", "None", \%args); +my $not_equal_str_filter = get_arg("nstr", "None", \%args); +my $non_empty_filter = get_arg("ne", "None", \%args); +my $empty_filter = get_arg("empty", "None", \%args); +my $pairs_file = get_arg("pairs", "", \%args); +my $range_filter = get_arg("rng", "None", \%args); +my $range_strict_filter = get_arg("rngs", "None", \%args); +my $reverse_c = get_arg("reverse", 0, \%args); +my $inverse = get_arg("inv", 0, \%args); +my $add_number = get_arg("a", 0, \%args); +my $subtract_number = get_arg("s", 0, \%args); +my $multiply_number = get_arg("m", 1, \%args); +my $divide_number = get_arg("d", 1, \%args); + +my $modulo_number = get_arg("mod", "", \%args); + +my $absolute_value = get_arg("ab", "", \%args); +my $floor = get_arg("floor", 0, \%args); +my $ceil = get_arg("ceil", 0, \%args); +my $round = get_arg("round", 0, \%args); +my $sign = get_arg("sign", 0, \%args); +my $take_length = get_arg("len", 0, \%args); +my $take_log = get_arg("log", 0, \%args); +my $take_log2 = get_arg("log2", 0, \%args); +my $take_log10 = get_arg("log10", 0, \%args); +my $nonpos_log = get_arg("nonpl", "0", \%args); +my $take_exp_by_e = get_arg("e", 0, \%args); +my $take_exp = get_arg("exp", "", \%args); +my $take_pow = get_arg("pow", "", \%args); +my $divide_by_column = get_arg("dc", "", \%args); +my $multiply_by_column = get_arg("mc", "", \%args); +my $subtract_column = get_arg("sc", "", \%args); +my $negative_to_positive = get_arg("neg2pos", "", \%args); +my $add_column = get_arg("ac", "", \%args); +my $accumulate = get_arg("cumul", 0, \%args); +my $zero_div_value = get_arg("zero", "999999", \%args); +my $min_column = get_arg("minc", "", \%args); +my $max_column = get_arg("maxc", "", \%args); + +my $set_min = get_arg("set_min", "", \%args); +my $set_max = get_arg("set_max", "", \%args); +my $skip = get_arg("skip", 0, \%args); +my $skip_columns = get_arg("skipc", 0, \%args); +my $substr = get_arg("substr", 0, \%args); +my $type = get_arg("type", "Number", \%args); +my $rm_regexp = get_arg("rmre", "", \%args); +my $to_regexp = get_arg("tore", "", \%args); +my $split_char = get_arg("splt_char", "", \%args); +my $pivot = get_arg("pv", 0, \%args); +my $pivot_val = get_arg("pv_val", 0.05, \%args); +my $pivot_high = get_arg("pv_high", 0, \%args); +my $pivot_low = get_arg("pv_low", 1, \%args); +my $split_del = get_arg("splt_d", "", \%args); +my $resolution = get_arg("res", "", \%args); +my $bins= get_arg("bins", "", \%args); +my $rescale= get_arg("rescale", "", \%args); +my $rescale_limits_set= get_arg("rescale_limits", "", \%args); +my $probdist= get_arg("pd", "", \%args); +my $subtract_mean= get_arg("z", "", \%args); +my $divide_mean= get_arg("dz", "", \%args); + +my @accumulator; +my %columns_hash; +my @columns_list; + +my $range_max; +my $range_min; +if ($range_filter ne "None"){ + ($range_min,$range_max)=($range_filter=~/^(\S+)\s*,\s*(\S+)/); +} +if ($range_strict_filter ne "None"){ + ($range_min,$range_max)=($range_strict_filter=~/^(\S+)\s*,\s*(\S+)/); +} + +my %rows_hash; +my @rows_list = split(/\,/, $rows,-1); +foreach my $r (@rows_list) { $rows_hash{$r} = "1"; } + +my $precision = get_arg("p", "", \%args); +my $add_str = get_arg("astr", "", \%args); +my $add_prefix_str = get_arg("bstr", "", \%args); +my $set_str = get_arg("set", "None", \%args); +my $quote = get_arg("quote", 0, \%args); + +if ($quote) +{ + $add_prefix_str = "\""; + $add_str = "\""; +} + +my %pairs; +if (length($pairs_file) > 0) +{ + open(PAIRS_FILE, "<$pairs_file"); + while() + { + chop; + + my @row = split(/\t/,-1); + + $pairs{$row[0]}{$row[1]} = "1"; + } +} + +my %equal_str_list_filter; +if (length($equal_str_list_filter_str) > 0) +{ + my @row = split(/;/, $equal_str_list_filter_str); + for (my $i = 0; $i < @row; $i++) + { + $equal_str_list_filter{$row[$i]} = "1"; + } +} + +my @headers; + + +my @col_max_array; +my @col_min_array; +my @col_sum_array; +my @col_possum_array; +my @col_count_array; +my $rescale_top; +my $rescale_bottom; +my $tmp_id=int(rand(100000000)); +my $prescan_file=0; +if ($bins ne "" or $rescale ne "" or $probdist ne "" or $subtract_mean ne "" or $divide_mean ne ""){ $prescan_file=1 } +my $rescale_limits_set_max ; +my $rescale_limits_set_min ; +if ($rescale ne ""){ + ($rescale_bottom, $rescale_top)=(split /\s*,\s*/,$rescale,-1); +} +if ($rescale_limits_set ne ""){ + $prescan_file=0; + ($rescale_limits_set_min, $rescale_limits_set_max)=(split /\s*,\s*/,$rescale_limits_set,-1); +} +if ($skip >= 1) +{ + my $line = <$file_ref>; + print "$line"; + chomp $line; + @headers = split(/\t/, $line,-1); +} + +for (my $i = 1; $i < $skip; $i++) +{ + my $line = <$file_ref>; + print "$line"; +} + + +if ($prescan_file){ + open (TMP,">tmp_$tmp_id"); + while (my $r=<$file_ref>){ + print TMP $r; + chomp $r; + my @row=split /\t/,$r,-1; + if ($#columns_list==-1){ + @columns_list=parseRanges($columns,$#row); + foreach my $c (@columns_list) { $columns_hash{$c} = "1"; } + } + for (my $i = 0; $i < scalar(@row); $i++) { + if (($columns_hash{$i} eq "1" or $apply_to_all_columns == 1) and pass_filter($row[0], $headers[$i], $row[$i])){ + $col_sum_array[$i]+=$row[$i]; + $col_count_array[$i]++; + if ($row[$i]>0){ + $col_possum_array[$i]+=$row[$i]; + } + if (!defined($col_max_array[$i]) or $col_max_array[$i]<$row[$i]){ + $col_max_array[$i]=$row[$i]; + } + if (!defined($col_min_array[$i]) or $col_min_array[$i]>$row[$i]){ + $col_min_array[$i]=$row[$i]; + } + } + } + } + close (TMP); + open (TMP,"tmp_$tmp_id"); + $file_ref=\*TMP; +} + +my $row_count=$skip-1; + +while (my $line=<$file_ref>) +{ + chomp $line; + $row_count++; + + if (!$rows_hash{All} and !$rows_hash{$row_count}) { + print "$line\n"; + next; + } + + my @row = split /\t/,$line,-1; + if ($#columns_list==-1){ + @columns_list=parseRanges($columns,$#row); + foreach my $c (@columns_list) { $columns_hash{$c} = "1"; } + } + + + for (my $i = 0; $i < $skip_columns; $i++) + { + print "$row[$i]\t"; + } + + + for (my $i = $skip_columns; $i < scalar(@row); $i++) + { + if (($columns_hash{$i} eq "1" or $apply_to_all_columns == 1) and &pass_filter($row[0], $headers[$i], $row[$i])) + { + my $num = $row[$i]; + + if ($substr != 0 ) + { + if (length($num) > $substr) + { + $num = substr($num, 0, $substr); + } + } + elsif (length($divide_by_column) > 0) + { + if (length($num) > 0) + { + if ($row[$divide_by_column] != 0) { $num /= $row[$divide_by_column]; } + elsif ($num == 0) { $num = 0; } + else { $num = $zero_div_value; } + } + } + elsif (length($multiply_by_column) > 0) + { + if (length($num) > 0) { $num *= $row[$multiply_by_column]; } + } + elsif ($inverse) + { + if (length($num) > 0) { + if ($num==0){ $num=$zero_div_value } + else{ $num=1/$num } + } + } + elsif (length($rescale) > 0) + { + if (length($num) > 0) { + if ($rescale_limits_set ne ""){ + $col_max_array[$i]=$rescale_limits_set_max; + $col_min_array[$i]=$rescale_limits_set_min; + } + if ($col_max_array[$i]==$col_min_array[$i]){ + $num=$rescale_bottom; + } + else{ + $num = ( $num-$col_min_array[$i]) * ( ($rescale_top-$rescale_bottom)/($col_max_array[$i]-$col_min_array[$i]) ) + $rescale_bottom; + } + } + } + elsif (length($bins) > 0) + { + if (length($num) > 0) { + my $binsize=($col_max_array[$i]-$col_min_array[$i])/$bins; + my $f = 0.5; + if ($num==$col_max_array[$i]){ + $f = -0.5 + } + $num = (int( ($num-$col_min_array[$i])/$binsize )+$f) * $binsize + $col_min_array[$i]; + } + } + elsif (length($probdist) > 0) + { + if (length($num) > 0) { + if ($num<0) { + $num=0; + } + else{ + $num = ($col_possum_array[$i] == 0 ? 0 : $num/$col_possum_array[$i]); + } + } + } + elsif (length($subtract_mean) > 0) + { + if (length($num) > 0) { + $num -= $col_sum_array[$i]/$col_count_array[$i]; + } + } + elsif (length($divide_mean) > 0) + { + if (length($num) > 0) { + $num /= $col_sum_array[$i]/$col_count_array[$i]; + } + } + elsif (length($subtract_column) > 0) + { + if (length($num) > 0) { $num -= $row[$subtract_column]; } + } + elsif (length($add_column) > 0) + { + if (length($num) > 0) { $num += $row[$add_column]; } + } + elsif (length($min_column) > 0) + { + $num = ($num < $row[$min_column]) ? $num : $row[$min_column]; + } + elsif (length($max_column) > 0) + { + $num = ($num < $row[$max_column]) ? $row[$max_column] : $num; + } + elsif ($take_length){ + $num = length($num); + } + elsif ($reverse_c) { + $num = reverse ($num); + } + elsif ($pivot == 1) + { + if (length($num) > 0 && $num =~ /^[0-9\.-]*[Ee]?[+0-9\.-]*$/) + { + if ($num > $pivot_val) + { + $num = $pivot_high; + } + else + { + $num = $pivot_low; + } + } + } + elsif (length($num) > 0 and $type eq "Number" and length($add_str) == 0 and length($add_prefix_str) == 0 and $set_str eq "None" && length($rm_regexp) == 0 && length($split_del) == 0 && length($split_char) == 0) + { + if ($accumulate){ $accumulator[$i] += $num; $num = $accumulator[$i] } + $num += $add_number; + $num -= $subtract_number; + $num *= $multiply_number; + $num = ($divide_number == 0 ? $zero_div_value : $num/$divide_number); + if ($modulo_number) { $num %= $modulo_number ; } + if ($take_log == 1) { $num = $num > 0 ? log($num) : $nonpos_log; } + if ($take_log2 == 1) { $num = $num > 0 ? log($num) / $LOG2 : $nonpos_log; } + if ($take_log10 == 1) { $num = $num > 0 ? log($num) / $LOG10 : $nonpos_log; } + if ($absolute_value ne "" and $num<0) { $num=$num*(-1); } + if ($floor == 1) { $num = floor($num); } + if ($ceil == 1) { $num = ceil($num); } +# if ($round == 1) { $num = int($num) + (($num - int($num)))/0.5 >=1 ? 1 : 0); } + if ($round == 1) { $num = abs(floor($num) - $num) < abs(ceil($num) - $num) ? floor($num) : ceil($num); } + if ($sign == 1) { $num = $num == 0 ? 0 : $num / abs($num); } + if ($take_exp_by_e == 1) { $num = exp($num); } + if (length($take_exp) > 0) { $num = $take_exp ** $num; } + if (length($take_pow) > 0) { $num = $num == 0 ? 0 : $num ** $take_pow; } + if (length($set_min) > 0 and $num < $set_min) { $num = $set_min; } + if (length($set_max) > 0 and $num > $set_max) { $num = $set_max; } + if (length($negative_to_positive) > 0 and $num < 0) { $num = -$num; } + if (length($resolution) > 0) { + my $tmp = $resolution * &format_number($num / $resolution, 0); $num = $num - $tmp < $tmp + $resolution - $num ? $tmp : $tmp + $resolution; } + } + elsif (length($rm_regexp) > 0) + { + $num =~ s/$rm_regexp/$to_regexp/g; + } + elsif (length($split_char) > 0) + { + my @split_col = split (//, $num); + $num = join ("$split_char", @split_col); + } + elsif (length($split_del) > 0) + { + my @split_col = split (/$split_del/, $num,-1); + $num = join ("\t", @split_col); + } + else + { + if ($set_str ne "None") + { + if ($set_str eq "EMPTY") { $num = ""; } + else { $num = $set_str; } + } + else + { + $num = "$add_prefix_str$num$add_str"; + } + } + + if ( length($precision) > 0 and looks_like_number($num) ) { $num = &format_number($num, $precision); } + + print "$num"; + + #print STDERR "MODIFYING [$row[0], $headers[$i]] --> VALUE [$row[$i]] --> [$num]\n"; + } + else + { + print "$row[$i]"; + } + + if ($i < scalar(@row) - 1) { print "\t"; } + } + + print "\n"; +} + +sub pass_filter +{ + my ($row_name, $column_name, $num) = @_; + + my $pass = 1; + + my $sci_number = $num =~ /^[\-]?[0-9\.]+[Ee][\-]?[0-9]+/; + + if ($num =~ /[A-Z]/ and $sci_number != 1) { if ($min_filter ne "None" or $max_filter ne "None" or $mins_filter ne "None" or $maxs_filter ne "None" or $range_filter ne "None" or $range_strict_filter ne "None") { $pass = 0; } } + + if ($min_filter ne "None" and $num < $min_filter) { $pass = 0; } + if ($max_filter ne "None" and $num > $max_filter) { $pass = 0; } + if ($mins_filter ne "None" and $num <= $mins_filter) { $pass = 0; } + if ($maxs_filter ne "None" and $num >= $maxs_filter) { $pass = 0; } + if ($range_filter ne "None" and ($range_max<$num or $range_min>$num)) { $pass = 0; } + if ($range_strict_filter ne "None" and ($range_max<=$num or $range_min>=$num)) { $pass = 0; } + if ($abs_filter ne "None" and abs($num) < $abs_filter) { $pass = 0; } + if ($below_abs_filter ne "None" and abs($num) > $below_abs_filter) { $pass = 0; } + if ($str_filter ne "None" and not($num =~ /$str_filter/)) { $pass = 0; } + if ($equal_str_filter ne "None" and $num ne $equal_str_filter) { $pass = 0; } + if ($equal_str_list_filter_str ne "None" and $equal_str_list_filter{$num} ne "1") { $pass = 0; } + if ($not_equal_str_filter ne "None" and $num eq $not_equal_str_filter) { $pass = 0; } + if ($non_empty_filter ne "None" and length($num) == 0) { $pass = 0; } + if ($empty_filter ne "None" and length($num) > 0) { $pass = 0; } + if (length($pairs_file) > 0 and $pairs{$row_name}{$column_name} ne "1") { $pass = 0; } + + return $pass; +} + +if ($prescan_file){ + close TMP; + unlink "tmp_$tmp_id"; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl + + Modifies a column according to predefined operations + + WHAT TO MODIFY: + + -c The column to modify (default: 0; specify multiple columns using commas) (zero-based) + -r The rows to modify (default: All except -skipped; specify multiple rows using commas) (zero-based) + -A Apply transformation to ALL columns + -min Apply transformation only if entry is above (or equal) num + -max Apply transformation only if entry is below (or equal) num + -mins Apply transformation only if entry is strictly above num + -maxs Apply transformation only if entry is strictly below num + -rng Apply transformation only if num1<=entry<=num2 + -rngs Apply transformation only if num1: Apply transformation only if entry is above or below - + -babs : Apply transformation only if entry is above - and below + -str : Apply transformation only if entry contains + -estr : Apply transformation only if entry is equal to + -nstr : Apply transformation only if entry is *not* equal to + -ne: Apply transormation only if entry is not empty + -empty: Apply transormation only if entry is empty + -pairs : Apply transformation only if the entry is from a row and column + that appear in a line of as + -skip : Skip num rows in the file (default: 0) + -skipc : Skip num columns (when applying to all columns, can skip the first few) (default: 0) + + HOW TO MODIFY: + + -a Add to the column (default: 0) + -s Substract to the column (default: 0) + -m Multiply column by (default: 1) (write '"-1"' to pass negative numbers) + -d Divide column by (default: 1) (write '"-1"' to pass negative numbers) + -mod Modulo column by (default: 1) (write '"-1"' to pass negative numbers) + -inv Inverse of column + -ab Absolute value of column + -floor Floor of column values + -ceil Ceiling of column values + -round Round to the nearest integer. Numbers that are halfway between two integers are rounded down (like int()) + -sign Sign of column values (+1 for positive, -1 for negative, 0 for zero) + -neg2pos Convert negative numbers to positive + -log Take log (natural base) of the column + -log2 Take log (base 2) of the column + -log10 Take log (base 10) of the column + -nonpl String to print out in case of non-positive log (default: "0") + -exp Take num ** (value of the column) + -e Take e=2.1782... ** (value of column) + -pow Raise vaule to the power of num (value of the column) + -substr If the column has more than num chars, then substr the first num + -set_min If the column has a value less than num, set it to num + -set_max If the column has a value greater than num, set it to num + -type : (default: Number) + -len Replace value (treated as a string) by its length in characters + -reverse Reverse the string (ABC becomes CBA) + + -dc Divide the column by the number in column + -mc Multiply the column by the number in column + -ac Add the number in column to the column + -sc Subtract the number in column from the column + -minc Take the min of the column and + -maxc Take the max of the column and + + -bins : discretize the column into bins. + -rescale given as 'bottom,top'. linearly rescales the data in the column so that the smallest value will + be and the largest will be . If the data is equal in all entries, all entries + will be set to . + -rescale_limits : given as 'min,max'. when used with -rescale assumes that the maximal value of the column is + max and the minimal value is min. + -pd makes the column a probability distribution by changing negative values to zero and + then dividing by the sum of the column. + -z Subtract mean + -dz Divide by mean + + -p Precision (take only sig. digits. default: don't fix) + -res Convert numbers to a resolution (e.g., 0.05) + -astr Add to the end of the column (default: "") + -bstr Add to the beginning of the column (default: "") + -quote Quote the column (add quotes before and after string) + -set Set the entry to (put EMPTY for getting an empty entry) + -rmre Remove string that matches the regular expression from column + + -pv Set numerical values around a given pivot (see -pv_val, -pv_high, -pv_low). Activated when = 1. + Non numerical values are not modified. + -pv_val The pivot value (default: 0.05) + -pv_high The number to set values greater then the pivot value (default: 0) + -pv_low The number to set values smaller equal then the pivot value (default: 1) + + -splt_d Split the column by the delimiter (default: none). + -cumul Accumulate (row i = row 1 + .. + row i) + -zero When dividing by zero, uses instead of giving an error (default: 999999) + + diff --git a/modules/local/pita/templates/lib/pita_run.pl b/modules/local/pita/templates/lib/pita_run.pl new file mode 100755 index 00000000..9b108222 --- /dev/null +++ b/modules/local/pita/templates/lib/pita_run.pl @@ -0,0 +1,197 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + + +my $CDS_FLANK = 200; +my $SITE_LENGTH = 25; + +my $POLY_A = "A" x $CDS_FLANK; + +my %args = load_args(\@ARGV); + +my $prefix = get_arg("prefix", "", \%args); +my $debug = get_arg("debug", 0, \%args); +my $utr_fn = get_arg("utr", "", \%args); +my $upstream_fn = get_arg("upstream", "", \%args); +my $mir_fn = get_arg("mir", "", \%args); +my $FLANK_UP = get_arg("flank_up", 0, \%args); +my $FLANK_DOWN = get_arg("flank_down", 0, \%args); +my $output_dir = get_arg("output", "", \%args); +my $DDG_AREA = get_arg("ddG_context", 70, \%args); +my $use_stab = get_arg("stab", 0, \%args); +my $limit = get_arg("limit", "", \%args); + +if ($output_dir ne "") +{ + $output_dir .= "/"; +} + + +my $echoed_pt_args = + echo_arg_quoted("l", \%args) . + echo_arg_quoted("gu", \%args) . + echo_arg_quoted("m", \%args) . + echo_arg_quoted("loop", \%args); + +my $r = int(rand(100000)); + +if ($utr_fn eq "") { die "Must provide UTR fasta file.\n"; } +if ($mir_fn eq "") { die "Must provide microRNA fasta file.\n";} + +## Step 0: Prepare extended UTR sequences + +if ($use_stab) +{ + dsystem ("cp $utr_fn tmp_utr_stab_$r"); + dsystem ("cp $mir_fn tmp_mir_stab_$r"); +} +else +{ + dsystem ("cat $utr_fn | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/dos2unix.pl | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/fasta2stab.pl > tmp_utr_stab_$r"); + dsystem ("cat $mir_fn | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/dos2unix.pl | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/fasta2stab.pl > tmp_mir_stab_$r"); +} + +if ($upstream_fn eq "") +{ + dsystem ("cat tmp_utr_stab_$r " . + "| cut -f 1 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/add_column.pl -s $POLY_A " . + "> tmp_prefix_$r;"); +} +else +{ + if ($use_stab) + { + dsystem ("cp $upstream_fn tmp_upstream_stab_$r"); + } + else + { + dsystem ("cat $upstream_fn | /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/fasta2stab.pl > tmp_upstream_stab_$r"); + } + + dsystem ("cat tmp_utr_stab_$r " . + "| cut -f 1 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/add_column.pl -s $POLY_A " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/join.pl -o A - tmp_upstream_stab_$r " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/merge_columns.pl -1 1 -2 2 " . + "> tmp_ext_utr_$r;"); + + dsystem ("cat tmp_ext_utr_$r " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/stab2length.pl " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cut.pl -f 1,1,2,2 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 2 -s " . ($CDS_FLANK-1) . " " . + ">tmp_ext_utr_pos_$r"); + + dsystem ("cat tmp_ext_utr_$r " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/extract_sequence.pl -f tmp_ext_utr_pos_$r " . + "> tmp_prefix_$r"); +} + +my $ext_utr_fn = $output_dir . $prefix . "ext_utr.stab"; + +dsystem ("/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/join.pl tmp_prefix_$r tmp_utr_stab_$r " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/add_column.pl -s $POLY_A " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/merge_columns.pl -1 1 -2 2 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/merge_columns.pl -1 1 -2 2 " . + "> " . $ext_utr_fn); + + + +## Step 1: Search potential targets + +print STDERR "Finding potential targets...\n"; +dsystem ("/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/find_potential_mirna_targets.pl tmp_utr_stab_$r -f tmp_mir_stab_$r $echoed_pt_args > tmp_pt_$r"); + +my $n_potential_targets = `wc -l tmp_pt_$r | sed 's/^ *//g' | cut -f 1 -d ' '`; +if (length($limit) > 0 and $n_potential_targets > $limit) +{ + dsystem ("/bin/rm -rf tmp_prefix_$r tmp_ext_utr_$r tmp_ext_utr_pos_$r tmp_prefix_$r tmp_pt_$r tmp_utr_stab_$r tmp_mir_stab_$r tmp_upstream_stab_$r"); + exit(1); +} + +## Step 2: Compute site scores + +print STDERR "Computing site scores...\n"; +dsystem ("cat tmp_pt_$r " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/join.pl -1 2 - $ext_utr_fn " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cut.pl -f 1-9,11- " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 2,3 -a $CDS_FLANK " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/RNAddG_compute.pl -ddgarea $DDG_AREA -upstream_rest $FLANK_UP -downstream_rest $FLANK_DOWN " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 2,3 -s $CDS_FLANK " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 9,10,11,12,13,14 -m '\"-1\"' " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cut.pl -f 1-15,14 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 15 -sc 14 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cut.pl -f 1-12,14-16,13 " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/modify_column.pl -c 9,10,11,12,13,14,15 -p 2 -m '\"-1\"' " . + "| /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/cap.pl \"UTR,microRNA,Start,End,Seed,Mismatchs,G:U,Loop,Site size,dGduplex,dG5,dG3,dG0,dG1,dGopen,ddG\" " . + "> " . $output_dir . $prefix . "pita_results.tab"); + + +## Clean up +if (not ($debug)) +{ + dsystem ("/bin/rm -rf tmp_prefix_$r tmp_ext_utr_$r tmp_ext_utr_pos_$r tmp_prefix_$r tmp_pt_$r tmp_utr_stab_$r tmp_mir_stab_$r tmp_upstream_stab_$r"); +} + +exit (0); + + +sub dsystem { + + my $cmd = $_[0]; + + if ($debug) { print STDERR "Executing $cmd\n"; } + system ($cmd); + +} + + +__DATA__ +syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/pita_run.pl [OPTIONS] + +Execute the PITA algorithm for identifying and scoring microRNA target sites. + +options: + -utr : fasta file containing the UTRs to be scanned + -mir : fasta file containing the microRNA sequences + -upstream : fasta file containing the upstream sequence for each UTR. The IDs + in should match the IDs found int the UTR file. If less 200 bp are + given (or if no file is given), it is padded with Poly-A. + -stab: All input files (utr, mir, upstream) are assumed to be stab files + rather than fasta files + + -flank_up + -flank_down : Flank requirement in basepairs (default: zero for both) + + -ddG_context : Number of bases upstream and downstream for target site that are + taken into account when folding the UTR (default: 70) + + -output : Path to where output files should be placed (default: current directory) + -prefix : Add the string as a prefix to the output files (pita_results.tab and ext_utr.stab) + -limit : Limit the run to potential targets (optional, no limit by default). Exits if limit is reached. + -debug Run in debug mode (leave untouched tmp files) + + + + Seed matching parameters: + + -l : Search for seed lengths of num1,...,num2 to the MicroRNA (default: 6-8) + + -gu : Lengths for which G:U wobbles are allowed and number of allowed wobbles. + Format of nums: ,,... (default: 6;0,7;1,8;1) + + -m : Lengths for which mismatches are allowed and number of allowed mismatches + Format of nums: ,,... + (default: 6;0,7;0,8;1) + + -loop : Lengths for which a single loop in either the target or the microrna is allowed + Format of nums: ,,... (default: none) diff --git a/modules/local/pita/templates/lib/sequence_helpers.pl b/modules/local/pita/templates/lib/sequence_helpers.pl new file mode 100755 index 00000000..58488398 --- /dev/null +++ b/modules/local/pita/templates/lib/sequence_helpers.pl @@ -0,0 +1,615 @@ +#!/usr/bin/perl + +use strict; +use POSIX; + +#------------------------------------------------------------------------------------------ +# SIGMA Calculation based on: http://proligo2.proligo.com/Calculation/calculation.html +#------------------------------------------------------------------------------------------ + +#------------------------------------------------------------------------------------------ +# GLOBALS +#------------------------------------------------------------------------------------------ +my @ALIGNMENT_HTML_COLORS = ( "cyan", "lime", "yellow", "red", "darkred" ); + +my %DNA; +$DNA{"A"} = 0; +$DNA{"C"} = 1; +$DNA{"G"} = 2; +$DNA{"T"} = 3; + +my %H; +$H{"AA"} = -7.9; +$H{"AC"} = -8.4; +$H{"AG"} = -7.8; +$H{"AT"} = -7.2; +$H{"CA"} = -8.5; +$H{"CC"} = -8; +$H{"CG"} = -10.6; +$H{"CT"} = -7.8; +$H{"GA"} = -8.2; +$H{"GC"} = -9.8; +$H{"GG"} = -8; +$H{"GT"} = -8.4; +$H{"TA"} = -7.2; +$H{"TC"} = -8.2; +$H{"TG"} = -8.5; +$H{"TT"} = -7.9; + +my %S; +$S{"AA"} = -22.2; +$S{"AC"} = -22.4; +$S{"AG"} = -21; +$S{"AT"} = -20.4; +$S{"CA"} = -22.7; +$S{"CC"} = -19.9; +$S{"CG"} = -27.2; +$S{"CT"} = -21; +$S{"GA"} = -22.2; +$S{"GC"} = -24.4; +$S{"GG"} = -19.9; +$S{"GT"} = -22.4; +$S{"TA"} = -21.3; +$S{"TC"} = -22.2; +$S{"TG"} = -22.7; +$S{"TT"} = -22.2; + +my %H_End; +$H_End{"A"} = 2.3; +$H_End{"C"} = 0.1; +$H_End{"G"} = 0.1; +$H_End{"T"} = 2.3; + +my %S_End; +$S_End{"A"} = 4.1; +$S_End{"C"} = -2.8; +$S_End{"G"} = -2.8; +$S_End{"T"} = 4.1; + +my $S_Symmetry = -1.4; + +my %epsilon1 = ('A' => 15.4, 'C' => 7.4, 'G' => 11.5, 'T' => 8.7); +my %epsilon2 = ( + 'A' => {'A' => 13.7, 'C' => 10.6, 'G' => 12.5, 'T' => 11.4}, + 'C' => {'A' => 10.6, 'C' => 7.3, 'G' => 9, 'T' => 7.6}, + 'G' => {'A' => 12.6, 'C' => 8.8, 'G' => 10.8, 'T' => 10}, + 'T' => {'A' => 11.7, 'C' => 8.1, 'G' => 9.5, 'T' => 9.4} + ); + +my %deltaS = ( + 'A' => {'A' => 24, 'C' => 17.3, 'G' => 20.8, 'T' => 23.9}, + 'C' => {'A' => 12.9, 'C' => 26.6, 'G' => 27.8, 'T' => 20.8}, + 'G' => {'A' => 13.5, 'C' => 26.7, 'G' => 26.6, 'T' => 17.3}, + 'T' => {'A' => 16.9, 'C' => 13.5, 'G' => 12.9, 'T' => 24}); +my %deltaH = ( + 'A' => {'A' => 9.1, 'C' => 6.5, 'G' => 7.8, 'T' => 8.6}, + 'C' => {'A' => 5.8, 'C' => 11, 'G' => 11.9, 'T' => 7.8}, + 'G' => {'A' => 5.6, 'C' => 11.1, 'G' => 11, 'T' => 6.5}, + 'T' => {'A' => 6, 'C' => 5.6, 'G' => 5.8, 'T' => 9.1}); + +# For cycle restriction + my %nimblegen_cycle_table = ( + "A" => 1, + "C" => 2, + "G" => 3, + "T" => 4, + "AA" => 4, + "AC" => 1, + "AG" => 2, + "AT" => 3, + "CA" => 3, + "CC" => 4, + "CG" => 1, + "CT" => 2, + "GA" => 2, + "GC" => 3, + "GG" => 4, + "GT" => 1, + "TA" => 1, + "TC" => 2, + "TG" => 3, + "TT" => 4); + +#------------------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------------------ +sub Reverse +{ + my ($sequence) = @_; + + my $res = ""; + + for (my $i = length($sequence) - 1; $i >= 0; $i--) + { + $res .= substr($sequence, $i, 1); + } + + return $res; +} + +#------------------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------------------ +sub ReverseComplement +{ + my ($sequence) = @_; + + my $res = reverse($sequence); + + $res =~ tr/ACGT/TGCA/; + + return $res; +} + +#------------------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------------------ +sub OLD_ReverseComplement +{ + my ($sequence) = @_; + + my $res = ""; + + my %complement; + $complement{"A"} = "T"; + $complement{"C"} = "G"; + $complement{"G"} = "C"; + $complement{"T"} = "A"; + + for (my $i = length($sequence) - 1; $i >= 0; $i--) + { + my $char = substr($sequence, $i, 1); + + my $char_complement = $complement{$char}; + + if (length($char_complement) > 0) { $res .= $char_complement; } + else { $res .= $char; } + } + + return $res; +} + +#------------------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------------------ +sub AlignmentFractionToHTMLColor +{ + my ($fraction, $str) = @_; + + my $res; + + if ($fraction > 0.2) + { + my $color; + if ($fraction < 0.3) { $color = $ALIGNMENT_HTML_COLORS[0]; } + elsif ($fraction > 0.8) { $color = $ALIGNMENT_HTML_COLORS[@ALIGNMENT_HTML_COLORS]; } + else { $color = $ALIGNMENT_HTML_COLORS[int(($fraction - 0.3) / 0.1)]; } + + #print STDERR "frac=$fraction "; + #print STDERR ($fraction - 0.3) / 0.1; + #print STDERR " "; + #print STDERR (int(($fraction - 0.3) / 0.1)); + #print STDERR "\n"; + + $res = "
        $str
        "; + } + else + { + $res = $str; + } + + return $res; +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeBackgroundToMatricesRatio +{ + my ($matrix_length) = @_; + + my $min = 0.00001; + my $max = 0.99999; + my $res = ($min + $max) / 2; + while ($max - $min > 0.00001) + { + my $value = log(1 - $res) - $matrix_length * log($res); + + if ($value > 0) + { + $min = $res; + } + else + { + $max = $res; + } + + $res = ($min + $max) / 2; + } + + return $res / (1.0 - $res); +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeNucleotideSetFraction () +{ + my ($sequence, $nucleotide_set, $raw_counts) = @_; + + my $sequence_length = length($sequence); + + my $eval_str = "(\$sequence =~ tr/[$nucleotide_set]//)"; + my $fraction = eval($eval_str); + + return $raw_counts == 1 ? $fraction : ($fraction / $sequence_length); +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeGCFraction () +{ + my ($sequence, $raw_counts) = @_; + + my $sequence_length = length($sequence); + my $gc_fraction = ($sequence =~ tr/[GC]//); + + return $raw_counts == 1 ? $gc_fraction : ($gc_fraction / $sequence_length); +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeMeltingTemperature +{ + my ($sequence, $TMMethod, $salt_concentration, $oligo_concentration) = @_; + + my $res = ""; + + my $sequence_length = length($sequence); + if ($sequence_length > 5) + { + my $gc_fraction = &ComputeGCFraction($sequence); + + if ($TMMethod eq "IDTDNA") + { + my $local_H; + $local_H += $H_End{substr($sequence, 0, 1)}; + $local_H += $H_End{substr($sequence, $sequence_length - 1, 1)}; + + my $local_S; + $local_S += $S_End{substr($sequence, 0, 1)}; + $local_S += $S_End{substr($sequence, $sequence_length - 1, 1)}; + + for (my $i = 0; $i < $sequence_length - 1; $i++) + { + my $dinucleotide = substr($sequence, $i, 2); + + $local_H += $H{$dinucleotide}; + $local_S += $S{$dinucleotide}; + } + + $local_H *= 1000; + + if (($sequence_length % 2 == 0 and substr($sequence, 0, $sequence_length / 2) eq substr($sequence, $sequence_length / 2, $sequence_length / 2)) or + (substr($sequence, 0, int($sequence_length / 2)) eq substr($sequence, int($sequence_length / 2) + 1, int($sequence_length / 2)))) + { + $local_S += $S_Symmetry; + } + + my $TM_1M_Na = $local_H / ($local_S + 1.987 * log($oligo_concentration / 2)); # Division by 2 is a hack to fit + + my $TM_final = 1 / ((1 / $TM_1M_Na) + (4.29 * $gc_fraction - 3.95) * 1e-5 * log($salt_concentration) + 9.4 * 1e-6 * log($salt_concentration) * log($salt_concentration)); + + $TM_final = &format_number($TM_final - 273.15, 3); + + $res = "$TM_final"; + } + elsif ($TMMethod eq "SIGMA") + { + my $seq = $sequence; + my ($aCount, $cCount, $gCount, $tCount) = GetCounts($seq); + my $GC = POSIX::floor(0.5 + (100 * ( $gCount + $cCount / 2) / length($seq))); + my $MW = (252 * $aCount + 228 * $cCount + 268 * $gCount + 243 * $tCount + 61 * (length($seq) - 1)); + my $epsilon = 0; + my @s = split(//, $seq); + for (my $i = 0; $i < length($seq) - 1; $i++) + { + $epsilon += 2 * $epsilon2{$s[$i]}{$s[$i+1]} - $epsilon1{$s[$i+1]}; + } + $epsilon += $epsilon1{$s[$#s]}; + my $quantity = 1000 / $epsilon; + my $ug = $quantity * $MW /1000; + + my $TM; + if (length($seq) <= 20) + { + $TM = (2 * ($aCount + $tCount) + 4 * ($gCount + $cCount)); + } + else + { + my $sigma_dH = 0; + my $sigma_dS = 0; + for (my $i = 0; $i < (length($seq) - 1); $i++) + { + $sigma_dH += $deltaH{$s[$i]}{$s[$i+1]}; + $sigma_dS += $deltaS{$s[$i]}{$s[$i+1]}; + } + $TM = (-1000 * $sigma_dH / (-10.8 - $sigma_dS + 1.987 * -23.5) + -273.15 + 16.6 * log($salt_concentration) / log(10)); + } + + $res = &format_number($TM, 3); + #print "SALT=$salt_concentration\n"; + #print "GC = $gc_fraction\n"; + #print "SeqLength = $sequence_length\n"; + } + elsif ($TMMethod eq "Nimblegen") + { + $res = &format_number(81.5 + 16.6 * log($salt_concentration) / log(10) + 41 * $gc_fraction - 600 / $sequence_length, 3); + #print "SALT=$salt_concentration\n"; + #print "GC = $gc_fraction\n"; + #print "SeqLength = $sequence_length\n"; + } + else + { + die ("TM Method $TMMethod not recognized\n"); + } + } + else + { + $res = "Too short"; + } + + return $res; +} + +sub GetCounts +{ + my $seq = shift; + my ($aCount,$cCount, $gCount, $tCount) = (0,0,0,0); + my @s = split(//, $seq, -1); + for (my $i = 0; $i < $#s; $i++) + { + if ($s[$i] eq "A") { $aCount++; } + elsif ($s[$i] eq "C") { $cCount++; } + elsif ($s[$i] eq "G") { $gCount++; } + elsif ($s[$i] eq "T") { $tCount++; } + else{ die ("probe contains illegal characters: $s[$i]\n"); } + } + return ($aCount,$cCount, $gCount, $tCount); +} + +#------------------------------------------------------------------------ +# @list ParseRanges (@ranges) +#------------------------------------------------------------------------ +sub ParseRanges +{ + my @segments = split(",", "@_"); + my @fields = (); + my ($i,$beg,$end,$inc) = (0,-1,-1,1); + my $seg; + + foreach $seg (@segments) + { + $beg = undef; + $end = undef; + $inc = undef; + + if($seg =~ /^(\d+)[-](\d+)$/) + { + $beg = $1; + $end = $2; + $inc = $beg <= $end ? +1 : -1; + } + elsif($seg =~ /^(\d+)$/) + { + $beg = $1; + $end = $1; + $inc = 1; + } + + if(defined($beg) and defined($end) and defined($inc)) + { + if ($inc > 0) + { + for($i = $beg; $i <= $end; $i += $inc) + { + push(@fields, $i); + } + } + else + { + for($i = $beg; $i >= $end; $i += $inc) + { + push(@fields, $i); + } + } + } + else + { + die("\nParseRanges() error: flag expected <\,><\-><\,>...<\,>, found: @_. Exit process.\n"); + } + } + @fields; +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeSynthesisCycles +{ + my ($seq) = @_; + + my $res = 1; + my $prev_id = -1; + for (my $i = length($seq) - 1; $i >= 0; $i--) + { + my $id = $DNA{substr($seq, $i, 1)}; + + if ($prev_id == -1) + { + $res += $id; + } + else + { + $res += $id > $prev_id ? ($id - $prev_id) : ($id - $prev_id + 4) + } + + $prev_id = $id; + } + + return $res; +} + +#-------------------------------------------------------------------------------------------------------- +# $DNA_sequence_verified_for_not_exceeding_probe_cycle_limit ProbeNotExceedsCycleLimit ($sequence) +#-------------------------------------------------------------------------------------------------------- +sub ComputeNimblegenCycles +{ + my $seq = $_[0]; + my $current_cycle = 0; + + my $prev_letter = ""; + for (my $i = 0; $i < length($seq); $i++) + { + my $c = substr($seq,$i,1); + $current_cycle += $nimblegen_cycle_table{$prev_letter.$c}; + $prev_letter = $c; + } + + return $current_cycle; +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub AlignSequenceOntoSequence +{ + my ($seq1, $seq2, $seq2_offset) = @_; + + my @res; + $res[0] = 0; + $res[1] = 0; + $res[2] = 0; + + for (my $i = 0; $i < length($seq1); $i++) + { + my $s1 = substr($seq1, $i, 1); + my $s2 = substr($seq2, $i + $seq2_offset, 1); + + if ($s1 ne $s2) + { + $res[0]++; + if ($i == length($seq1) - 1) + { + $res[2]=1; # Mismatch was at last position + } + } + + if (($s1 eq "C" and $s2 eq "T") or ($s1 eq "A" and $s2 eq "G")) + { + $res[1]++; + } + } + + #print STDERR "Aligning s1=$seq1 s2=$seq2 s2_offset=$seq2_offset Mismatches=$res[0] NonGUMismatches=" . ($res[0]-$res[1]) . " GU_Wobbles=$res[1]\n"; + + return @res; # res[0]=#Mismatches, res[1]=#G:U wobbles +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub AlignSequences +{ + my ($seq1, $seq2, $max_offset, $max_mutations, $max_non_aligned) = @_; + + my $seq1_length = length($seq1); + my $seq2_length = length($seq2); + + my @res; + + for (my $i = 0; $i <= $max_offset; $i++) + { + my $mutations = &ComputeMismatchesBetweenAlignedSequences($seq1, 0, $seq1_length - 1, $seq2, $i, $max_mutations, $max_non_aligned); + + if ($mutations != -1) + { + $res[0] = $i; + $res[1] = $mutations; + + last; + } + } + + if (length($res[0]) == 0) + { + for (my $i = 1; $i <= $max_offset; $i++) + { + my $mutations = &ComputeMismatchesBetweenAlignedSequences($seq2, 0, $seq2_length - 1, $seq1, $i, $max_mutations, $max_non_aligned); + + if ($mutations != -1) + { + $res[0] = -$i; + $res[1] = $mutations; + + last; + } + } + } + + #print STDERR "AlignSequences between seq1=$seq1 and seq2=$seq2 max_offset=$max_offset max_mutations=$max_mutations max_non_aligned=$max_non_aligned res=[offset=$res[0] mutations=$res[1]]\n"; + + return @res; # res[0]=offset_by_which_seq1_moves res[1]=#Mismatches res[0]="" if not found +} + +#------------------------------------------------------------------------------ +# +#------------------------------------------------------------------------------ +sub ComputeMismatchesBetweenAlignedSequences +{ + my ($seq1, $seq1_start, $seq1_end, $seq2, $seq2_start, $max_mutations, $max_non_aligned) = @_; + + my $res = 0; + my $non_aligned = 0; + + for (my $i = $seq1_start; $i <= $seq1_end; $i++) + { + my $s1 = substr($seq1, $i, 1); + my $s2 = substr($seq2, $i + $seq2_start, 1); + + if (length($s2) == 0) + { + $non_aligned++; + + if ($non_aligned > $max_non_aligned) + { + $res = -1; + + last; + } + } + elsif ($s1 ne $s2) + { + $res++; + + if ($res > $max_mutations) + { + $res = -1; + + last; + } + } + } + + #print STDERR "ComputeMismatchesBetweenAlignedSequences between seq1=$seq1($seq1_start,$seq1_end) and seq2=$seq2($seq2_start,...) max_mutations=$max_mutations max_non_aligned=$max_non_aligned res=$res\n"; + + return $res; +} + +#print ComputeBackgroundToMatricesRatio(157) . "\n"; +#print ComputeMeltingTemperature("ACCCTTCAGCAGTTCCACACACCCTTCAGCAGTTCCACACACCCTTCAGCAGTTCCACAC", "Nimblegen", 0.2, 0) . "\n"; +#print AlignSequences($ARGV[0], $ARGV[1], $ARGV[2], $ARGV[3], $ARGV[4]); + +1 diff --git a/modules/local/pita/templates/lib/stab2length.pl b/modules/local/pita/templates/lib/stab2length.pl new file mode 100755 index 00000000..6503a3d5 --- /dev/null +++ b/modules/local/pita/templates/lib/stab2length.pl @@ -0,0 +1,65 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/format_number.pl"; +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/system.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $include_sequence = get_arg("s", 0, \%args); +my $print_all = get_arg("a", 0, \%args); + +while(<$file_ref>) +{ + chop; + + my @row = split(/\t/); + + print "$row[0]\t"; + print length($row[1]); + + if ($include_sequence == 1) + { + print "\t$row[1]"; + } + elsif ($print_all == 1) + { + for (my $i = 1; $i <= @row; $i++) + { + print "\t$row[$i]"; + } + } + + print "\n"; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/stab2length.pl + + Outputs the length of each sequence + + -s: Include the sequence in the output file + + -a: Prints additional fields if exist + diff --git a/modules/local/pita/templates/lib/system.pl b/modules/local/pita/templates/lib/system.pl new file mode 100755 index 00000000..87db6079 --- /dev/null +++ b/modules/local/pita/templates/lib/system.pl @@ -0,0 +1,104 @@ +#!/usr/bin/perl + +use strict; + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub AppendToFile +{ + system("echo \"$_[1]\" >> $_[0]"); +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub CreateDir +{ + my $dir = $_[0]; + if (!(-d $dir)) { system("mkdir $dir"); } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub CopyFile +{ + if (FileExists($_[0])) + { + system("cp $_[0] $_[1]"); + } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub DeleteFile +{ + if (FileExists($_[0])) + { + system("rm $_[0]"); + } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub FileExists +{ + if (-e $_[0]) { return 1; } + else { return 0; } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub FileIsADirectory +{ + if (-d $_[0]) { return 1; } + else { return 0; } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub GetNumLinesInFile +{ + my $r = int(rand 1000000000); + + system("wc $_[0] > tmp.$r"); + + open(TMP, "; + chop $line; + + $line =~ /([^\s]+)/; + + &DeleteFile("tmp.$r"); + + return $1; +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub LinkFile +{ + if (!(-l $_[1])) + { + system("ln -s $_[0] $_[1]"); + } +} + +#------------------------------------------------------------------------------------- +# +#------------------------------------------------------------------------------------- +sub MoveFile +{ + if (FileExists($_[0])) + { + system("mv $_[0] $_[1]"); + } +} + +1 diff --git a/modules/local/pita/templates/lib/tab2feature_gxt.pl b/modules/local/pita/templates/lib/tab2feature_gxt.pl new file mode 100755 index 00000000..d30b9966 --- /dev/null +++ b/modules/local/pita/templates/lib/tab2feature_gxt.pl @@ -0,0 +1,281 @@ +#!/usr/bin/perl + +use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $name = get_arg("n", "Gene names", \%args); +my $desc = get_arg("d", "", \%args); +my $org = get_arg("o", "", \%args); +my $genome_ver = get_arg("gv", "NA", \%args); +my $fixed_positive_color = get_arg("c", "", \%args); +my $fixed_positive_color_by_list_str = get_arg("cs", "", \%args); +my $fixed_negative_color = get_arg("mc", "", \%args); +my $zero_color_intensity = get_arg("zeroc", "", \%args); +my $min_color_intensity = get_arg("minc", "-10", \%args); +my $max_color_intensity = get_arg("maxc", "", \%args); +my $display_mode = get_arg("m", "By Types", \%args); +my $location_display_mode = get_arg("l", "Color gradient", \%args); +my $location_height = get_arg("lh", 10, \%args); +my $use_fixed_type_ordering = get_arg("fixed_order", 0, \%args); +my $display_track_information = get_arg("dt", 0, \%args); +my $add_feature_name_to_id = get_arg("af", 0, \%args); +my $add_counter_to_id = get_arg("ai", "", \%args); +my $feature_vector = get_arg("v", 0, \%args); +my $chromosome_starts = get_arg("chr_starts", "", \%args); +my $chromosome_ends = get_arg("chr_ends", "", \%args); +my $footer_pixels = get_arg("fp", 5, \%args); + +if (length($chromosome_starts) > 0) { $chromosome_starts = "ChromosomesStarts=\"$chromosome_starts\""; } +if (length($chromosome_ends) > 0) { $chromosome_ends = "ChromosomesEnds=\"$chromosome_ends\""; } + +my $type = $feature_vector == 1 ? "ChromosomeFeatureVectorTrack" : "ChromosomeFeatureTrack"; + +if (length($desc) > 0) +{ + $desc = &remove_illegal_xml_chars($desc); + $desc =~ s/\t/ /g; +} + +print " 0) +{ + my @row = split(/\;/, $fixed_positive_color_by_list_str); + for (my $i = 0; $i < @row; $i += 2) + { + $fixed_positive_color_by_list{$row[$i]} = $row[$i + 1]; + } +} + +my @features; +my %feature_types2id; +my @feature_types; +my $feature_counter = 0; + +my $curr_type; +while(<$file_ref>) +{ + chop; + + my @row = split(/\t/); + $curr_type = &remove_illegal_xml_chars($row[4]); + if (length($feature_types2id{$curr_type}) == 0) + { + $feature_types2id{$curr_type} = $feature_counter++; + push(@feature_types, $curr_type); + } + + push(@features, $_); +} + +print "NumLocations=\"".($#features+1)."\" FeatureTypes=\""; +for (my $i = 0; $i < @feature_types; $i++) +{ + if ($i > 0) { print ";" } + + print "$feature_types[$i]"; +} +print "\" "; + +for (my $i = 0; $i < @feature_types; $i++) +{ + print "ColorGradientMaxPositiveColor_$i=\"" . &get_positive_color($i, $feature_types[$i]) . "\" "; + print "ColorGradientMinNegativeColor_$i=\"" . &get_negative_color($i) . "\" "; + + if (length(get_arg("zeroc$i", "", \%args)) > 0) + { + print "ColorGradientZeroValue_$i=\"" . get_arg("zeroc$i", "", \%args) . "\" "; + } + elsif (length($zero_color_intensity) > 0) + { + print "ColorGradientZeroValue_$i=\"$zero_color_intensity\" "; + } + + if (length(get_arg("minc$i", "", \%args)) > 0) + { + print "ColorGradientMinNegativeValue_$i=\"" . get_arg("minc$i", "", \%args) . "\" "; + } + elsif (length($min_color_intensity) > 0) + { + print "ColorGradientMinNegativeValue_$i=\"$min_color_intensity\" "; + } + + if (length(get_arg("maxc$i", "", \%args)) > 0) + { + print "ColorGradientMaxPositiveValue_$i=\"" . get_arg("maxc$i", "", \%args) . "\" "; + } + elsif (length($max_color_intensity) > 0) + { + print "ColorGradientMaxPositiveValue_$i=\"$max_color_intensity\" "; + } +} + +print ">\n"; + +my $counter = 1; +for (my $i = 0; $i < @features; $i++) +{ + my @row = split(/\t/, $features[$i], 6); + $curr_type = &remove_illegal_xml_chars($row[4]); + if ($add_feature_name_to_id == 1) { $row[1] .= " ($feature_types2id{$curr_type})"; } + if ($add_counter_to_id == 1) { $row[1] .= " (ID$counter)"; $counter++;} + + print "$row[0]\t$row[1]\t$row[2]\t$row[3]\t$feature_types2id{$curr_type}\t$row[5]\n"; +} + +print "\n"; + +sub get_positive_color () +{ + my ($color_index, $feature_name) = @_; + + my $res = $fixed_positive_color; + + if (length($res) == 0) + { + $res = get_arg("c$color_index", "", \%args); + + if (length($res) == 0 and length($fixed_positive_color_by_list_str) > 0) + { + foreach my $str (keys %fixed_positive_color_by_list) + { + if ($feature_name =~ /$str/) + { + $res = $fixed_positive_color_by_list{$str}; + last; + } + } + } + + if (length($res) == 0) + { + if ($color_index % 18 == 0) { $res = "255,0,0,1"; } + if ($color_index % 18 == 1) { $res = "0,0,255,1"; } + if ($color_index % 18 == 2) { $res = "255,128,128,1"; } + if ($color_index % 18 == 3) { $res = "128,0,64,1"; } + if ($color_index % 18 == 4) { $res = "128,255,128,1"; } + if ($color_index % 18 == 5) { $res = "50,1,131,1"; } + if ($color_index % 18 == 6) { $res = "0,0,0,1"; } + if ($color_index % 18 == 7) { $res = "0,128,255,1"; } + if ($color_index % 18 == 8) { $res = "255,128,192,1"; } + if ($color_index % 18 == 9) { $res = "128,128,192,1"; } + if ($color_index % 18 == 10) { $res = "255,128,64,1"; } + if ($color_index % 18 == 11) { $res = "255,255,128,1"; } + if ($color_index % 18 == 12) { $res = "128,0,255,1"; } + if ($color_index % 18 == 13) { $res = "128,128,0,1"; } + if ($color_index % 18 == 14) { $res = "0,89,45,1"; } + if ($color_index % 18 == 15) { $res = "0,255,128,1"; } + if ($color_index % 18 == 16) { $res = "0,255,0,1"; } + if ($color_index % 18 == 17) { $res = "128,255,255,1"; } + } + } + + return $res; +} + +sub get_negative_color () +{ + my ($color_index) = @_; + + my $res = $fixed_negative_color; + + if (length($res) == 0) + { + $res = get_arg("mc$color_index", "", \%args); + + if (length($res) == 0) + { + $res = "0,255,0,1"; + } + } + + return $res; +} + +sub remove_illegal_xml_chars +{ + my $str = $_[0]; + $str =~ s/\&/&/g; + $str =~ s/\"/"/g; + $str =~ s/\'/'/g; + $str =~ s/\/>/g; + $str =~ s/;/,/g; + return $str; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/tab2feature_gxt.pl + + Creates a feature gxt file from a tab file + + -n : Name of the chromosome track (default: Features ) + -o : Organism + -gv : Genome Version (default: NA) + -d : Track description (Tabs will be converted to spaces, default: empty) + + -c : Fix the max color for all features to be str (e.g., '255,0,0,1') + -c: Fix the max color for feature to be str (e.g., '255,0,0,1') + -cs : Fix the max color for features that contain words from the list to colors + specified in the list. The format of list is: + for specifying that features whose name contain str1 are set to color1 + -mc : Fix the min color for all features to be str (e.g., '255,0,0,1') + -mc : Fix the min color for feature to be str (e.g., '255,0,0,1') + + -zeroc : Fix the zero color intensity for all features to be num + -minc : Fix the min color intensity for all features to be num + -maxc : Fix the max color intensity for all features to be num + -minc : Fix the min color intensity for feature to be + -maxc : Fix the max color intensity for feature to be + -zeroc :Fix the zero color intensity for feature to be + + -m : Display mode (Full/Packed/Dense/By Types) (default: By Types) + -l : Location Display mode (Color gradient/Filled box/Unfilled box/Filled oval/Unfilled oval/Directed filled box/Directed unfilled box) (default: Color gradient) + -lh : Location height (default: 10) + + -fixed_order: Use a fixed ordering on the feature types + + -dt: Display track information + -fp : Footer pixels (spacing below the track). + + -af: Add the id of the feature to the name/id of the feature + -ai: Add a counter id to each instance + + -v: Feature vector + + -chr_starts Chromosome start locations (optional format: ;...) + -chr_ends Chromosome end locations (optional format: ;...) + diff --git a/modules/local/pita/templates/lib/transpose.pl b/modules/local/pita/templates/lib/transpose.pl new file mode 100755 index 00000000..1dfe99b8 --- /dev/null +++ b/modules/local/pita/templates/lib/transpose.pl @@ -0,0 +1,125 @@ +#!/usr/bin/perl + +############################################################################## +############################################################################## +## +## /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/transpose.pl +## +############################################################################## +############################################################################## +## +## Written by Josh Stuart in the lab of Stuart Kim, Stanford University. +## +## Email address: jstuart@stanford.edu +## Phone: (650) 725-7612 +## +## Postal address: Department of Developmental Biology +## Beckman Center Room B314 +## 279 Campus Dr. +## Stanford, CA 94305 +## +## Web site: http://www.smi.stanford.edu/people/stuart +## +############################################################################## +############################################################################## +## +## Written: 00/00/02 +## Updated: 00/00/02 +## +############################################################################## +############################################################################## + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/libfile.pl"; + +use strict; +use warnings; + +# Flush output to STDOUT immediately. +$| = 1; + +my @flags = ( + [ '-q', 'scalar', 0, 1] + , [ '-d', 'scalar', "\t", undef] + , ['--file', 'scalar', '-', undef] + , [ '-nd', 'scalar', "\t", undef] + ); + +my %args = %{&parseArgs(\@ARGV, \@flags)}; + +if(exists($args{'--help'})) +{ + print STDOUT ; + exit(0); +} + +my $verbose = not($args{'-q'}); +my $delim = $args{'-d'}; +my $newDelim= $args{'-nd'}; +my $file = $args{'--file'}; +my $r = 0; +my $c = 0; +my $ncols = -1; +my @x; +my $filep; + +$verbose and print STDERR "Reading in table from '$file'..."; +open($filep, $file) or die("Could not open file '$file' for reading"); +while(<$filep>) +{ + chomp; + my @row = split($delim,$_,-1); + + for($c = 0; scalar(@row) > 0; $c++) + { + $x[$r][$c] = shift @row; + } + if($c > $ncols) + { + $ncols = $c; + } + $r++; +} +close($filep); + +my $nrows = $r; + +$verbose and print STDERR " done ($nrows by $ncols).\n"; + +$verbose and print STDERR "Transposing to $ncols by $nrows...\n"; +for($c = 0; $c < $ncols; $c++) +{ + for($r = 0; $r < $nrows; $r++) + { + my $x = defined($x[$r][$c]) ? $x[$r][$c] : ''; + print "$x"; + if($r < $nrows - 1) + { print $newDelim; } + } + print "\n"; +} +$verbose and print STDERR " done.\n"; + +exit(0); + +__DATA__ +syntax: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/transpose.pl [OPTIONS] [FILE | < FILE] + +Transposes a table -- flips the rows and columns so that what +were columns in the original table become the rows and what +were rows in the original table become the columns. The original +file is assumed to have rows delimited by newlines and columns +delimited by tabs (the column delimiter can actually be set with +the -d flag; see below). + +FILE: a file containing a table with each row containing a tuple + and each field in the tuple seperated by a delimiter. By + default, the delimiter is assumed to be tab. + +OPTIONS are: +-d DELIM: set the delimiter for the columns to DELIM (default is + tab). + +-nd NEWDELIM set the delimiter for the columns in the output to NEWDELIM (default is tab). + + + diff --git a/modules/local/pita/templates/lib/uniquify.pl b/modules/local/pita/templates/lib/uniquify.pl new file mode 100755 index 00000000..4074965b --- /dev/null +++ b/modules/local/pita/templates/lib/uniquify.pl @@ -0,0 +1,120 @@ +#!/usr/bin/perl + +#use strict; + +require "/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/load_args.pl"; + +if ($ARGV[0] eq "--help") +{ + print STDOUT ; + exit; +} + +my $file_ref; +my $file = $ARGV[0]; +if (length($file) < 1 or $file =~ /^-/) +{ + $file_ref = \*STDIN; +} +else +{ + open(FILE, $file) or die("Could not open file '$file'.\n"); + $file_ref = \*FILE; +} + +my %args = load_args(\@ARGV); + +my $uniquify_columns = get_arg("c", 0, \%args); +my $force_numbers_on_all = get_arg("f", 0, \%args); +my $delim = get_arg("d", "-", \%args); +my $group_columns = get_arg("g", "0",\%args); + +my %counters; + +my @columns = (); +if ($uniquify_columns =~ /\d/) +{ + for (split /,/, $uniquify_columns) + { + if (/(\d+)-(\d+)/) + { + push @columns, ($1..$2); + } + else + { + push @columns, $_ ; + } + } + my %unique = (); + @columns = grep { ! $unique{$_}++ } @columns; +} + + +my %unique = map { $_ => (); } @columns; + + +while(<$file_ref>) +{ + chop; + + my @values = split(/\t/); + + if ($group_columns) + { + my $con_value=""; + foreach my $col (@columns) + { + $con_value = $con_value . "**" . $values[$col]; + #delete $values[$col]; + } + #print "con value: $con_value\n"; + + my $value = $con_value; + if ($force_numbers_on_all) + { + $unique{$con_value} or $unique{$con_value}++ ; + } + if (my $suffix = $unique{$con_value}++) + { + $unique{$con_value = sprintf "%s${delim}%i", $value, $suffix}++; + } + + my $length= @columns; + my $last_val= $columns[$length-1]; + my @uniq_vals= split(/\*\*/, $con_value); + my $len_uniq= @uniq_vals; + $values[$last_val]= $uniq_vals[$len_uniq-1]; + } + + else + { + for my $column (@columns) + { + my $value = $values[$column]; + if ($force_numbers_on_all) + { + $unique{$column}{$value} or $unique{$column}{$value}++ ; + } + if (my $suffix = $unique{$column}{$value}++) + { + $unique{$column}{$values[$column] = sprintf "%s${delim}%i", $value, $suffix}++; + } + } + } + print join ("\t", @values) . "\n"; +} + +__DATA__ + +/nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/uniquify.pl + + Takes in a tab delimited file and uniquifies a column: whenever + encountering an entry that already appeared, appends a number + to that column "-1", "-2", ... + + -c : Columns to uniquify (zero based, default: 0), may be several columns, e.g. -c 0,2-4,7 + -g <1/0>: Group colums inorder to uniquify them together. Default is 0.Forexamle running: /nfs/data3/CIRCEST/pipeline_sponging/modules/local/pita/templates/lib/uniquify.pl -c 1-3 -g 1 will treat coloumns 1-3 as one and uniquify their concatenation. -f: Force a number even on first occurrence + (default: first occurrence does not get a number appended) + + + -d : Use as delimiter instead of the default '-' character. diff --git a/modules/local/pita/templates/lib/vector_ops.pl b/modules/local/pita/templates/lib/vector_ops.pl new file mode 100755 index 00000000..e4caff45 --- /dev/null +++ b/modules/local/pita/templates/lib/vector_ops.pl @@ -0,0 +1,869 @@ +#!/usr/bin/perl + +use strict; + +my $MUTUAL_INFORMATION = "mi"; +my $DOT_PRODUCT = "dot"; +my $CORRELATION_COEFFICIENT = "cor"; +my $LOG2 = log(2); + +#-------------------------------------------------------------------------------- +# DEBUG_VO +#-------------------------------------------------------------------------------- +sub DEBUG_VO +{ +# print $_[0]; +} + +#--------------------------------------------------------- +# vec_avg +#--------------------------------------------------------- +sub vec_avg($) +{ + my $vec = shift; + + my $sum = vec_sum($vec); + + my $entries = vec_count_full_entries($vec); + #print "sum=$sum entries=$entries\n"; + return $entries > 0 ? $sum / $entries : ""; +} + +#--------------------------------------------------------- +# best_dot_product +#--------------------------------------------------------- +sub vec_best_dot_product($$) +{ + my ($vecX, $vecY) = @_; + + my $best_dot = ""; + + my $sizeX = @$vecX; + my $sizeY = @$vecY; + + if ($sizeX >= $sizeY) + { + for (my $X_offset = 0; $sizeX - $X_offset >= $sizeY; $X_offset++) + { + my $dot = 0; + for (my $i = 0; $i < $sizeY; $i++) + { + $dot += ($$vecX[$i + $X_offset] * $$vecY[$i]); + } + + if (length($best_dot) == 0 or $dot > $best_dot) + { + $best_dot = $dot; + } + } + } + else + { + for (my $Y_offset = 0; $sizeY - $Y_offset >= $sizeX; $Y_offset++) + { + my $dot = 0; + for (my $i = 0; $i < $sizeX; $i++) + { + $dot += ($$vecY[$i + $Y_offset] * $$vecX[$i]); + } + + if (length($best_dot) == 0 or $dot > $best_dot) + { + $best_dot = $dot; + } + } + } + + return $best_dot; +} + +#--------------------------------------------------------- +# center +#--------------------------------------------------------- +sub vec_center($) +{ + my $vec = shift; + + my $avg = vec_avg($vec); + my $std = vec_std($vec); + + my @res; + for (my $i = 0; $i < @$vec; $i++) + { + $res[$i] = (length($$vec[$i]) > 0 and $std > 0) ? (($$vec[$i] - $avg) / $std) : ""; + } + + return @res; +} + +#--------------------------------------------------------- +# center (by reference) +#--------------------------------------------------------- +sub vec_center_by_ref($) +{ + my $vec = shift; + + my $avg = vec_avg($vec); + my $std = vec_std($vec); + + for (my $i = 0; $i < @$vec; $i++) + { + $$vec[$i] = (length($$vec[$i]) > 0 and $std > 0) ? (($$vec[$i] - $avg) / $std) : ""; + } + +} + +#--------------------------------------------------------- +# vec_compute_score +#--------------------------------------------------------- +sub vec_compute_score ($$$) +{ + my ($vecX, $vecY, $op) = @_; + + if ($op eq $MUTUAL_INFORMATION) { return vec_mutual_information($vecX, $vecY); } + elsif ($op eq $DOT_PRODUCT) { return vec_dot_product($vecX, $vecY); } + elsif ($op eq $CORRELATION_COEFFICIENT) { return vec_correlation($vecX, $vecY); } +} + +#--------------------------------------------------------- +# vec_correlation +#--------------------------------------------------------- +sub vec_correlation ($$) +{ + my ($vecX, $vecY) = @_; + + my $total = @$vecX; + + my $sum_X = 0; + my $sum_XX = 0; + my $sum_Y = 0; + my $sum_YY = 0; + my $sum_XY = 0; + my $num = 0; + + for (my $i = 0; $i < $total; $i++) + { + my $p_X = $$vecX[$i]; + my $p_Y = $$vecY[$i]; + + if($p_X =~ /\S/ and $p_Y =~ /\S/) + { + $sum_X += $p_X; + $sum_XX += $p_X * $p_X; + $sum_Y += $p_Y; + $sum_YY += $p_Y * $p_Y; + $sum_XY += $p_X * $p_Y; + $num++; + } + } + + my $correlation = undef; + + my $numerator = ($num * $sum_XY) - ($sum_X * $sum_Y); + my $var_X = ($num * $sum_XX) - ($sum_X * $sum_X); + my $var_Y = ($num * $sum_YY) - ($sum_Y * $sum_Y); + + if ($var_X > 0 && $var_Y > 0) + { + my $denominator = sqrt($var_X * $var_Y); + $correlation = $numerator / $denominator; + } + + return $correlation; +} + +#--------------------------------------------------------- +# vec_count_full_entries +#--------------------------------------------------------- +sub vec_count_full_entries($) +{ + my $vec = shift; + + my $entries = 0; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0) { $entries++; } } + + return $entries; +} + +#--------------------------------------------------------- +# dot_product +#--------------------------------------------------------- +sub vec_dot_product ($$) +{ + my ($vecX, $vecY) = @_; + + my $dot = 0; + for (my $i = 0; $i < @$vecX; $i++) + { + $dot += ($$vecX[$i] * $$vecY[$i]); + } + return $dot; +} + +#--------------------------------------------------------- +# dot_product_normedX +#--------------------------------------------------------- +sub vec_dot_product_normedX ($$) +{ + my ($vecX, $vecY) = @_; + + my $dot = 0; + my $norm = 0; + for (my $i = 0; $i < @$vecX; $i++) + { + $dot += ($$vecX[$i] * $$vecY[$i]); + $norm += abs($$vecX[$i]); + } + + return ($norm > 0) ? ($dot/$norm) : ""; +} + +#--------------------------------------------------------- +# entropy +#--------------------------------------------------------- +sub vec_entropy ($) +{ + my $vecX = shift; + + DEBUG_VO("entropy for\n"); + DEBUG_VO(" Vec: @$vecX\n"); + + my $total = @$vecX; + + my %COUNTS_X; + for (my $i = 0; $i < $total; $i++) + { + my $key_X = $$vecX[$i]; + + if (length($COUNTS_X{$key_X} == 0)) { $COUNTS_X{$key_X} = 1; } else { $COUNTS_X{$key_X} = $COUNTS_X{$key_X} + 1; } + } + + my $entropy = 0; + foreach my $key_X (keys %COUNTS_X) + { + my $p_X = $COUNTS_X{$key_X} / $total; + + DEBUG_VO(" PX($key_X) = $p_X\n"); + + $entropy -= ($p_X) * log($p_X) / $LOG2; + } + + return $entropy; +} + +#--------------------------------------------------------- +# intersect +#--------------------------------------------------------- +sub vec_intersect ($$) +{ + my ($vecX, $vecY) = @_; + + my @res; + my $counter = 0; + + my %h1; + for (my $i = 0; $i < @$vecX; $i++) { $h1{$$vecX[$i]} = "1"; } + + for (my $i = 0; $i < @$vecY; $i++) { if ($h1{$$vecY[$i]} eq "1") { $res[$counter++] = $$vecY[$i]; $h1{$$vecY[$i]} = ""; } } + + return @res; +} + +#--------------------------------------------------------- +# kl distance +#--------------------------------------------------------- +sub vec_kl_distance ($$$) +{ + my ($vecX, $vecY, $variable_dimension) = @_; + + my $res = 0; + + for (my $i = 0; $i < @$vecX; $i += $variable_dimension) + { + for (my $j = 0; $j < $variable_dimension; $j++) + { + $res += $$vecX[$i + $j] * log($$vecX[$i + $j] / $$vecY[$i + $j]); + $res += $$vecY[$i + $j] * log($$vecY[$i + $j] / $$vecX[$i + $j]); + } + } + + return $res; +} + +#--------------------------------------------------------- +# vec_min +#--------------------------------------------------------- +sub vec_min ($) +{ + my $vec = shift; + + my $min = 1e300; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] < $min) { $min = $$vec[$i]; } } + + return $min; +} + +#--------------------------------------------------------- +# vec_first_entry_ge_ind +#--------------------------------------------------------- +sub vec_first_entry_ge_ind($) +{ + my $vec = shift; + my $val = $_[1]; + + my $ind = ""; + for (my $i = 0; $i < @$vec; $i++) { + if ($$vec[$i]>=$val){$ind=$i;last;} + } + + return $ind; +} + +#--------------------------------------------------------- +# vec_first_entry_le_ind +#--------------------------------------------------------- +sub vec_first_entry_le_ind($) +{ + my $vec = shift; + my $val = $_[1]; + + my $ind = ""; + for (my $i = 0; $i < @$vec; $i++) { + if ($$vec[$i]<=$val){$ind=$i;last;} + } + + return $ind; +} + + +#--------------------------------------------------------- +# vec_first_nonempty_entry_ind +#--------------------------------------------------------- +sub vec_first_nonempty_entry_ind ($) +{ + my $vec = shift; + + my $ind = ""; + for (my $i = 0; $i < @$vec; $i++) { + if ($$vec[$i] ne ""){$ind=$i;last;} + } + + return $ind; +} + +#--------------------------------------------------------- +# vec_max_ind +#--------------------------------------------------------- +sub vec_max_ind ($) +{ + my $vec = shift; + my $ind = ""; + my $max = -1e300; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] > $max) { $max = $$vec[$i]; $ind = $i} } + + return $ind; +} + +#--------------------------------------------------------- +# vec_min_ind +#--------------------------------------------------------- +sub vec_min_ind ($) +{ + my $vec = shift; + my $ind = ""; + my $min = 1e300; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] < $min) { $min = $$vec[$i]; $ind = $i} } + + return $ind; +} + +#--------------------------------------------------------- +# vec_max +#--------------------------------------------------------- +sub vec_max ($) +{ + my $vec = shift; + + my $max = -1e300; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] > $max) { $max = $$vec[$i]; } } + + return $max; +} + +#--------------------------------------------------------- +# vec_median +#--------------------------------------------------------- +sub vec_median ($) +{ + my $vec = shift; + + my @full_vec; + foreach my $num (@$vec) + { + if (length($num) > 0) + { + push(@full_vec, $num); + } + } + + @full_vec = sort { $a <=> $b } @full_vec; + + my $counts = @full_vec; + + # BEFORE WAS: return ($counts % 2 == 1) ? $full_vec[int($counts / 2)] : ($full_vec[int($counts / 2) - 1] + $full_vec[int($counts / 2)]) / 2 + # CHANGED NOV18,2007 because one property of median (e.g., comparing to mean) is that it is an original value of the set, and the above solution (for the even set size case) doesnt respect it... + return $full_vec[int($counts / 2)]; +} + +#--------------------------------------------------------- +# vec_true_median - here if the vec has even number of members +# we compute the mean of the two center members +#--------------------------------------------------------- +sub vec_true_median ($) +{ + my $vec = shift; + + my @full_vec; + foreach my $num (@$vec) + { + if (length($num) > 0) + { + push(@full_vec, $num); + } + } + + @full_vec = sort { $a <=> $b } @full_vec; + + my $counts = @full_vec; + + return ($counts % 2 == 1) ? ($full_vec[int($counts / 2)]) + : (($full_vec[int($counts / 2) - 1] + $full_vec[int($counts / 2)]) / 2); +} + +#--------------------------------------------------------- +# vec_quantile +#--------------------------------------------------------- +sub vec_quantile ($$) +{ + my $vec = @_[0]; + my $quantile = @_[1]; + + my @full_vec; + foreach my $num (@$vec) + { + if (length($num) > 0) + { + push(@full_vec, $num); + } + } + + @full_vec = sort { $a <=> $b } @full_vec; + + my $counts = @full_vec; + + my $save_quantile = $quantile; + if ($quantile < 0) + { + $quantile = 0; + } + elsif ($quantile >= 1) + { + $save_quantile = (($counts - 1)/$counts); + } + + return $full_vec[int($save_quantile * $counts)]; +} + +#--------------------------------------------------------- +# vec_num_above_or_equal_min +#--------------------------------------------------------- +sub vec_num_above_or_equal_min ($$) +{ + my $vec = @_[0]; + my $min = @_[1]; + + my $res = 0; + + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] >= $min) { $res++; } } + + return $res; +} + +#--------------------------------------------------------- +# vec_num_below_or_equal_max +#--------------------------------------------------------- +sub vec_num_below_or_equal_max ($$) +{ + my $vec = @_[0]; + my $max = @_[1]; + + my $res = 0; + + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0 && $$vec[$i] <= $max) { $res++; } } + + return $res; +} + +#--------------------------------------------------------- +# mutual_information +#--------------------------------------------------------- +sub vec_mutual_information ($$) +{ + my ($vecX, $vecY) = @_; + + + + DEBUG_VO("mutual_information between\n"); + DEBUG_VO(" X: @$vecX\n"); + DEBUG_VO(" Y: @$vecY\n"); + + my $total = @$vecX; + + my %COUNTS_X; + my %COUNTS_Y; + my %COUNTS_XY; + for (my $i = 0; $i < $total; $i++) + { + my $key_X = $$vecX[$i]; + my $key_Y = $$vecY[$i]; + my $key_XY = $$vecX[$i] . " " . $$vecY[$i]; + + if (length($COUNTS_X{$key_X} == 0)) { $COUNTS_X{$key_X} = 1; } else { $COUNTS_X{$key_X} = $COUNTS_X{$key_X} + 1; } + if (length($COUNTS_Y{$key_Y} == 0)) { $COUNTS_Y{$key_Y} = 1; } else { $COUNTS_Y{$key_Y} = $COUNTS_Y{$key_Y} + 1; } + if (length($COUNTS_XY{$key_XY} == 0)) { $COUNTS_XY{$key_XY} = 1; } else { $COUNTS_XY{$key_XY} = $COUNTS_XY{$key_XY} + 1; } + + #DEBUG_VO(" $i: X[$key_X]=$COUNTS_X{$key_X}\n"); + #DEBUG_VO(" Y[$key_Y]=$COUNTS_Y{$key_Y}\n"); + #DEBUG_VO(" XY[$key_XY]=$COUNTS_XY{$key_XY}\n"); + } + + my $mi = 0; + foreach my $key_XY (keys %COUNTS_XY) + { + my ($key_X, $key_Y) = split(" ", $key_XY); + + my $p_X = $COUNTS_X{$key_X} / $total; + my $p_Y = $COUNTS_Y{$key_Y} / $total; + my $p_XY = $COUNTS_XY{$key_XY} / $total; + + DEBUG_VO(" PX($key_X) = $p_X\n"); + DEBUG_VO(" PY($key_Y) = $p_Y\n"); + DEBUG_VO(" PXY($key_XY) = $p_XY\n"); + + $mi += ($p_XY) * log($p_XY / ($p_X * $p_Y)); + } + + return $mi; +} + +#--------------------------------------------------------- +# vec_nth_statistic +#--------------------------------------------------------- +sub vec_nth_statistic ($$) +{ + my $vec = @_[0]; + my $nth_statistic = @_[1]; + + my @sorted_vec = sort { $a <=> $b } @$vec; + + return $sorted_vec[$nth_statistic]; +} + +#--------------------------------------------------------- +# pearson +#--------------------------------------------------------- +sub vec_pearson ($$) +{ + my ($vecX, $vecY) = @_; + + my $dot = 0; + my $num = 0; + for (my $i = 0; $i < @$vecX; $i++) + { + if (length($$vecX[$i]) > 0 and length($$vecY[$i]) > 0) + { + $dot += ($$vecX[$i] * $$vecY[$i]); + $num++; + } + } + + my $pearson = $num > 0 ? $dot / $num : -1000; + + return $pearson; +} + +#--------------------------------------------------------- +# vec_stats +#--------------------------------------------------------- +sub vec_permute (\@$) +{ + my ($vec_str) = @_; + + my @vec = @{$vec_str}; + + my $n = @vec; + + while($n>1){ + $n--; + my $new_index = int(rand($n+1)); + + my $tmp = $vec[$n]; + $vec[$n] = $vec[$new_index]; + $vec[$new_index] = $tmp; + } + + return @vec; +} + +#--------------------------------------------------------- +# vec_stats +#--------------------------------------------------------- +sub vec_stats ($) +{ + my $vec = @_[0]; + + my %stats = 0; + for (my $i = 0; $i < @$vec; $i++) { if (length($stats{$$vec[$i]}) > 0) { $stats{$$vec[$i]} = $stats{$$vec[$i]} + 1; } else { $stats{$$vec[$i]} = 1; } } + + return %stats; +} + +#--------------------------------------------------------- +# vec_mad +#--------------------------------------------------------- +sub vec_mad ($) +{ + my $vec = shift; + + my $true_med = vec_true_median($vec); + # print "\n"; + my @diff_vec = (); + for (my $i = 0; $i < @$vec; $i++) { push(@diff_vec, abs($$vec[$i] - $true_med));} + #print "\n"; + #for (my $i = 0; $i < @$vec; $i++) { print "diff\t".$diff_vec[$i]."\n";} + my $res = vec_true_median(\@diff_vec); + + return $res; +} + +#--------------------------------------------------------- +# vec_std +#--------------------------------------------------------- +sub vec_std($) +{ + my $vec = shift; + + my $sum_x = 0; + my $sum_xx = 0; + for (my $i = 0; $i < @$vec; $i++) { $sum_x += $$vec[$i]; $sum_xx += $$vec[$i] * $$vec[$i]; } + + my $entries = vec_count_full_entries($vec); + + my $std = $entries > 0 ? $sum_xx / $entries - (($sum_x / $entries) * ($sum_x / $entries)) : ""; + + return $std > 0 ? sqrt($std) : 0; +} + + +#--------------------------------------------------------- +# vec_std +#--------------------------------------------------------- +sub vec_stderr ($) +{ + my $vec = @_[0]; + + my $sum_x = 0; + my $sum_xx = 0; + for (my $i = 0; $i < @$vec; $i++) { $sum_x += $$vec[$i]; $sum_xx += $$vec[$i] * $$vec[$i]; } + + my $entries = vec_count_full_entries($vec); + + my $stderr = $entries > 0 ? $sum_xx / $entries - (($sum_x / $entries) * ($sum_x / $entries)) : ""; + $stderr = $entries > 0 ? $stderr / $entries : $stderr; + + return sqrt($stderr); +} + +#--------------------------------------------------------- +# vec_sum +#--------------------------------------------------------- +sub vec_sum($) +{ + my $vec = shift; + + my $sum = 0; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0) { $sum += $$vec[$i]; } } + + return $sum; +} + +#--------------------------------------------------------- +# vec_product +#--------------------------------------------------------- +sub vec_product($) +{ + my $vec = shift; + + my $product = 1; + for (my $i = 0; $i < @$vec; $i++) { if (length($$vec[$i]) > 0) { $product *= $$vec[$i]; } } + + return $product; +} + +#--------------------------------------------------------- +# vec_sum_log +#--------------------------------------------------------- +sub vec_sum_log($) +{ + my $vec = shift; + + my $sum = 0; + my $not_done = 1; + my $first_val = -1; + + for (my $i = 0; ($i < @$vec) && ($not_done == 1); $i++) + { + if (length($$vec[$i]) > 0) + { + $sum = $$vec[$i]; + $first_val = $i; + $not_done = 0; + } + } + + for (my $i = ($first_val + 1); $i < @$vec; $i++) + { + if (length($$vec[$i]) > 0) + { + my $x = $$vec[$i]; + my $y = $sum; + if ($x >= $y) + { + $y -= $x; + } + else + { + my $t = $x; + $x = $y; + $y = $t - $x; + } + $sum = $x + log(1 + exp($y)); + } + } + + return $sum; +} + +#--------------------------------------------------------- +# vec_union +#--------------------------------------------------------- +sub vec_union ($$) +{ + my ($vecX, $vecY) = @_; + + my @res; + my $counter = 0; + + my %h1; + for (my $i = 0; $i < @$vecX; $i++) { $h1{$$vecX[$i]} = "1"; } + for (my $i = 0; $i < @$vecY; $i++) { $h1{$$vecY[$i]} = "1"; } + + for my $key (keys %h1) + { + $res[$counter++] = $key; + } + + return @res; +} + +#--------------------------------------------------------- +# vec_window_average +#--------------------------------------------------------- +sub vec_window_average ($$) +{ + my $vec = @_[0]; + my $window_size = @_[1]; + + my @res; + + for (my $i = 0; $i < @$vec; $i++) + { + my $start = $i - $window_size >= 0 ? $i - $window_size : 0; + my $end = $i + $window_size < @$vec ? $i + $window_size : @$vec - 1; + my $sum = 0; + my $count = 0; + for (my $j = $start; $j <= $end; $j++) + { + if (length($$vec[$j])>0){ + $sum += $$vec[$j]; + $count++; + } + } + if ($count>0){ + $res[$i] = $sum / $count; + } + else{ + $res[$i] = ""; + } + } + + return @res; +} + +#--------------------------------------------------------- +# vec_window_max +#--------------------------------------------------------- +sub vec_window_max ($$) +{ + my $vec = @_[0]; + my $window_size = @_[1]; + + my @res; + + for (my $i = 0; $i < @$vec; $i++) + { + my $start = $i - $window_size >= 0 ? $i - $window_size : 0; + my $end = $i + $window_size < @$vec ? $i + $window_size : @$vec - 1; + my $max = ""; + for (my $j = $start; $j <= $end; $j++) + { + if (length($max) == 0 or $$vec[$j] > $max) + { + $max = $$vec[$j]; + } + } + $res[$i] = $max; + } + + return @res; +} + +#--------------------------------------------------------- +# vec_window_min +#--------------------------------------------------------- +sub vec_window_min ($$) +{ + my $vec = @_[0]; + my $window_size = @_[1]; + + my @res; + + for (my $i = 0; $i < @$vec; $i++) + { + my $start = $i - $window_size >= 0 ? $i - $window_size : 0; + my $end = $i + $window_size < @$vec ? $i + $window_size : @$vec - 1; + my $min = ""; + for (my $j = $start; $j <= $end; $j++) + { + if (length($min) == 0 or $$vec[$j] < $min) + { + $min = $$vec[$j]; + } + } + $res[$i] = $min; + } + + return @res; +} + +1 From 41f29deefa5b1bd9e123a68dbd3f752d837de278 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:23:00 +0200 Subject: [PATCH 29/53] removing artifact in sponge.R --- modules/local/sponge/templates/sponge.R | 1 - 1 file changed, 1 deletion(-) diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/templates/sponge.R index f1ab5fad..8d42276a 100644 --- a/modules/local/sponge/templates/sponge.R +++ b/modules/local/sponge/templates/sponge.R @@ -21,7 +21,6 @@ bindingsites_matrix <- as.matrix(bindingsites) # load gene expression genes <- read.csv("${gene_expr}", sep = "\\t", row.names = "tx") -genes <- subset(genes, select = -gene_id) gene_expr <- t(as.matrix(genes)) From 17313919b9c34ff99f850a373c59f60ce4f9eea1 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:24:07 +0200 Subject: [PATCH 30/53] adding tarpmir process --- modules/local/tarpmir/main.nf | 12 ++++++------ modules/local/tarpmir/templates/TarPmiR_threading.py | 7 +++++-- 2 files changed, 11 insertions(+), 8 deletions(-) diff --git a/modules/local/tarpmir/main.nf b/modules/local/tarpmir/main.nf index 3b5c6e63..08f70a6c 100644 --- a/modules/local/tarpmir/main.nf +++ b/modules/local/tarpmir/main.nf @@ -1,25 +1,25 @@ process TARPMIR { tag "$meta.id" - label 'process_medium' + label 'process_high' conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? - 'oras://community.wave.seqera.io/library/miranda_viennarna_pip_numpy_pruned:d46fd1a59195bfaf' : - 'community.wave.seqera.io/library/miranda_viennarna_pip_numpy_pruned:f4624328aba4ca2b' }" + 'oras://community.wave.seqera.io/library/miranda_viennarna_numpy_scikit-learn_pruned:57cdf91f9c9e30b0' : + 'community.wave.seqera.io/library/miranda_viennarna_numpy_scikit-learn_pruned:f0d4942abcefbe2f' }" input: tuple val(meta) , path(fasta) tuple val(meta2), path(mature) output: - tuple val(meta), path("${prefix}.txt") , emit: bindings - tuple val(meta), path("*.txt") , emit: txt - path "versions.yml" , emit: versions + tuple val(meta), path("${prefix}.bindings.bp"), emit: bindings + path "versions.yml" , emit: versions when: task.ext.when == null || task.ext.when script: + prefix = task.ext.prefix ?: "${meta.id}" template 'TarPmiR_threading.py' stub: diff --git a/modules/local/tarpmir/templates/TarPmiR_threading.py b/modules/local/tarpmir/templates/TarPmiR_threading.py index d6aa942f..6ec80c45 100644 --- a/modules/local/tarpmir/templates/TarPmiR_threading.py +++ b/modules/local/tarpmir/templates/TarPmiR_threading.py @@ -14,6 +14,8 @@ import urllib import subprocess import pickle +import sklearn +import platform import uuid import pymysql import ssl @@ -655,8 +657,8 @@ def main(): mir_path="${mature}" mrna_path="${fasta}" mode_path="${moduleDir}/Human_sklearn_0.22.pkl" - pb_cut=float(0.8) # TODO MALTE - n_threads_input=10 # TODO MALTE + pb_cut=float(0.8) # TODO: make param in nextflow.config + n_threads_input=12 output_file="${meta.id}.bindings.tsv" global sessionID @@ -748,6 +750,7 @@ def main(): "RNAplfold": rnaplfold_version, "RNAduplex": rnaduplex_version, "miranda": miranda_version, + "sklearn": sklearn.__version__, } } From b0fb25bd2e816c71c6401f7d102745120edf10e3 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:24:38 +0200 Subject: [PATCH 31/53] ordering imports --- subworkflows/local/mirna/mirna_bindingsites.nf | 11 ++++++----- 1 file changed, 6 insertions(+), 5 deletions(-) diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index e5b905a8..11f5f7e4 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -1,13 +1,14 @@ include { BIOAWK as ADD_BACKSPLICE } from '../../../modules/nf-core/bioawk' -include { MIRANDA } from '../../../modules/nf-core/miranda' +include { CAT_CAT as COMBINE_BINDINGSITES } from '../../../modules/nf-core/cat/cat' include { GAWK as UNIFY_MIRANDA } from '../../../modules/nf-core/gawk' -include { TARGETSCAN } from '../../../modules/local/targetscan/predict' include { GAWK as UNIFY_TARGETSCAN } from '../../../modules/nf-core/gawk' -include { TARPMIR } from '../../../modules/local/tarpmir' include { GAWK as UNIFY_TARPMIR } from '../../../modules/nf-core/gawk' -include { MIRNA_TARGETS } from '../../../modules/local/mirna_targets' -include { CAT_CAT as COMBINE_BINDINGSITES } from '../../../modules/nf-core/cat/cat' include { MAJORITY_VOTE } from '../../../modules/local/majority_vote' +include { MIRANDA } from '../../../modules/nf-core/miranda' +include { MIRNA_TARGETS } from '../../../modules/local/mirna_targets' +include { PITA } from '../../../modules/local/pita' +include { TARGETSCAN } from '../../../modules/local/targetscan/predict' +include { TARPMIR } from '../../../modules/local/tarpmir' workflow MIRNA_BINDINGSITES { take: From 25e71a805997f16bae7a476688dc3dd25cdbfd1c Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:25:54 +0200 Subject: [PATCH 32/53] adding pita and tarpmir to tool selection --- nextflow_schema.json | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/nextflow_schema.json b/nextflow_schema.json index 68ad3992..ab08cdc7 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -178,8 +178,8 @@ "fa_icon": "fas fa-wrench", "description": "Comma separated list of miRNA bindingsite prediction tools to use. Supported tools: miranda, targetscan.", "help_text": "Select one or a combination of miRNA bindingsite prediction tools for the pipeline e.g:\n--mirna_tools 'miranda,targetscan'", - "default": "miranda,targetscan,tarpmir", - "pattern": "^((miranda|targetscan|tarpmir)?,?)*[^,]+$" + "default": "miranda,targetscan,tarpmir,pita", + "pattern": "^((miranda|targetscan|tarpmir,pita)?,?)*[^,]+$" }, "mirna_tool_filter": { "type": "integer", From 1373e395f8a8403673f44d34615c54a178473696 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:33:21 +0200 Subject: [PATCH 33/53] reformatting --- modules/local/sponge_effects/main.nf | 5 +++-- 1 file changed, 3 insertions(+), 2 deletions(-) diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge_effects/main.nf index e2047f21..933fce8a 100644 --- a/modules/local/sponge_effects/main.nf +++ b/modules/local/sponge_effects/main.nf @@ -11,8 +11,8 @@ process SPONGE_EFFECTS { tuple val(meta), path(sponge_data) output: - // TODO - path "versions.yml" , emit: versions + // TODO: script can't be executed yet + path "versions.yml", emit: versions when: @@ -22,6 +22,7 @@ process SPONGE_EFFECTS { template 'sponge_effects.R' stub: + // TODO """ touch "test.txt" From e4840587d4324cb907483aa0dddb3f918ea9d535 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:33:47 +0200 Subject: [PATCH 34/53] adding SPONGE_EFFECTS versions --- subworkflows/local/mirna_prediction.nf | 5 +++-- 1 file changed, 3 insertions(+), 2 deletions(-) diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index fd2892cb..3c47df47 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -89,13 +89,14 @@ workflow MIRNA_PREDICTION { ch_tx_normalized = TX_NORMALIZATION(tx_counts).normalized ch_versions = ch_versions.mix(TX_NORMALIZATION.out.versions) - + SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_tx_normalized, ch_mirna_filtered) ch_versions = ch_versions.mix(SPONGE.out.versions) SPONGE_EFFECTS(SPONGE.out.sponge_data) - + + ch_versions = ch_versions.mix(SPONGE_EFFECTS.out.versions) emit: versions = ch_versions From 76464710e520b1c4b27764e7ad51deef13d1592c Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 11:34:15 +0200 Subject: [PATCH 35/53] adding pita in mirna_prediction for testing --- .../local/mirna/mirna_bindingsites.nf | 24 +++++++++++++------ 1 file changed, 17 insertions(+), 7 deletions(-) diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index 11f5f7e4..adea18db 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -1,5 +1,4 @@ include { BIOAWK as ADD_BACKSPLICE } from '../../../modules/nf-core/bioawk' -include { CAT_CAT as COMBINE_BINDINGSITES } from '../../../modules/nf-core/cat/cat' include { GAWK as UNIFY_MIRANDA } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARGETSCAN } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARPMIR } from '../../../modules/nf-core/gawk' @@ -30,8 +29,7 @@ workflow MIRNA_BINDINGSITES { .splitFasta(by: 100, file: true) .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} - // - // MIRNA PREDICTION TOOLS: + // // MIRNA PREDICTION TOOLS: // tools_selected = params.mirna_tools.split(',').collect{it.trim().toLowerCase()} @@ -76,17 +74,29 @@ workflow MIRNA_BINDINGSITES { ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) } + if (tools_selected.contains('pita')) { + // + // TARPMIR WORKFLOW: + // + + PITA( ch_transcriptome_batches, mirna_fasta.collect() ) + // UNIFY_TARPMIR( TARPMIR.out.bindings, [] ) + + ch_versions = ch_versions.mix(PITA.out.versions) + // ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) + // ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) + } + // // CONSOLIDATE PREDICTIONS WORKFLOW: // // TODO: This is an artifact and should be removed if we have a replacement - // consolidate_targets = TARGETSCAN.out.txt.join(MIRANDA.out.txt).join(circrna_bed12) - consolidate_targets = TARGETSCAN.out.txt.join(MIRANDA.out.txt) + // consolidate_targets = TARGETSCAN.out.txt.join(MIRANDA.out.txt) - MIRNA_TARGETS( consolidate_targets ) + // MIRNA_TARGETS( consolidate_targets ) - ch_versions = ch_versions.mix(MIRNA_TARGETS.out.versions) + // ch_versions = ch_versions.mix(MIRNA_TARGETS.out.versions) // // MAJORITY VOTING: From c07f510e788724de88d502802e47cfcdeef9b496 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 15:24:31 +0200 Subject: [PATCH 36/53] adding pita params --- .../local/pita/templates/pita_prediction.pl | 6 ++--- nextflow.config | 4 ++++ nextflow_schema.json | 24 +++++++++++++++++++ 3 files changed, 31 insertions(+), 3 deletions(-) diff --git a/modules/local/pita/templates/pita_prediction.pl b/modules/local/pita/templates/pita_prediction.pl index 803f8e64..8de04b72 100755 --- a/modules/local/pita/templates/pita_prediction.pl +++ b/modules/local/pita/templates/pita_prediction.pl @@ -13,9 +13,9 @@ my \$mir_fn = '${mature}'; my \$flank_up = get_arg("flank_up", "", \\%args); my \$flank_down = get_arg("flank_down", "", \\%args); -my \$lengths = '6-8'; -my \$gu = '6;0,7;1,8;1'; -my \$mismatches = '6;0,7;0.8;1'; +my \$lengths = '${params.pita_lengths}' +my \$gu = '${params.pita_wobbles}' +my \$mismatches = '${params.pita_mismatches}' my \$loop = get_arg("loop", "", \\%args); my \$gxp = get_arg("gxp", "", \\%args); diff --git a/nextflow.config b/nextflow.config index e48c366a..e2ad891f 100644 --- a/nextflow.config +++ b/nextflow.config @@ -89,6 +89,10 @@ params { mirna_tool_filter = 1 mirna_correlation = 'pearson' + //> PITA options + pita_lengths = '6-8' + pita_wobbles = '6;0,7;1,8;1' + pita_mismatches = '6;0,7;0,8;1' //> SPONGE sponge_fdr = 0.01 diff --git a/nextflow_schema.json b/nextflow_schema.json index ab08cdc7..5cbe7a35 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -190,6 +190,30 @@ "minimum": 1, "maximum": 4 }, + "pita_lengths": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "A parameter for PITA which controls the range of seed lengths for microRNA interactions.", + "help_text": "Search for seed lengths of num1,...,num2 to the MicroRNA (default: 6-8), where the values represent the minimum and maximum number of nucleotides in the seed sequence.", + "default": "6-8", + "pattern": "^(\\d*-\\d*)" + }, + "pita_wobbles": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "A parameter for PITA that defines the seed lengths where G:U wobbles (mismatched pairs) are allowed.", + "help_text": "Lengths for which G:U wobbles are allowed and number of allowed wobbles. Format of nums: ,,... (default: 6;0,7;1,8;1)", + "default": "6;0,7;1,8;1", + "pattern": "^((\\d*;\\d*),)?(\\d*;\\d*)" + }, + "pita_mismatches": { + "type": "string", + "fa_icon": "fas fa-wrench", + "description": "A parameter for PITA that defines the seed lengths where mismatches are allowed and the number of permitted mismatches.", + "help_text": "Lengths for which mismatches are allowed and number of allowed mismatches. Format of nums: ,,... (default: 6;0,7;0,8;1)", + "default": "6;0,7;0,8;1", + "pattern": "^((\\d*;\\d*),)?(\\d*;\\d*)" + }, "sponge_fdr": { "type": "number", "fa_icon": "fas fa-circle-notch", From ad001a429c0ed947e294e0076ccc01cd0df40fbe Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 15:24:44 +0200 Subject: [PATCH 37/53] adding tarpmir params --- .../local/tarpmir/templates/TarPmiR_threading.py | 4 ++-- nextflow.config | 4 ++++ nextflow_schema.json | 14 ++++++++++++++ 3 files changed, 20 insertions(+), 2 deletions(-) diff --git a/modules/local/tarpmir/templates/TarPmiR_threading.py b/modules/local/tarpmir/templates/TarPmiR_threading.py index 6ec80c45..8955094b 100644 --- a/modules/local/tarpmir/templates/TarPmiR_threading.py +++ b/modules/local/tarpmir/templates/TarPmiR_threading.py @@ -657,8 +657,8 @@ def main(): mir_path="${mature}" mrna_path="${fasta}" mode_path="${moduleDir}/Human_sklearn_0.22.pkl" - pb_cut=float(0.8) # TODO: make param in nextflow.config - n_threads_input=12 + pb_cut=float(${params.tarpmir_cut}) + n_threads_input=${params.tarpmir_threads} output_file="${meta.id}.bindings.tsv" global sessionID diff --git a/nextflow.config b/nextflow.config index e2ad891f..051a7530 100644 --- a/nextflow.config +++ b/nextflow.config @@ -89,6 +89,10 @@ params { mirna_tool_filter = 1 mirna_correlation = 'pearson' + //> TARPMIR options + tarpmir_threads = 12 + tarpmir_cut = 0.8 + //> PITA options pita_lengths = '6-8' pita_wobbles = '6;0,7;1,8;1' diff --git a/nextflow_schema.json b/nextflow_schema.json index 5cbe7a35..b20f9647 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -190,6 +190,20 @@ "minimum": 1, "maximum": 4 }, + "tarpmir_cut": { + "type": "number", + "fa_icon": "fas fa-circle-notch", + "description": "Probability cut, which defines a true miRNA-mRNA binding site. (e.g. 0.5, means that it's a true binding site if the prediction proability >0.5)", + "help_text": "A float number which defines the cutoff for a true miRNA-mRNA binding site.", + "default": 0.8 + }, + "tarpmir_threads": { + "type": "integer", + "fa_icon": "fas fa-intersection", + "description": "Defines the number of threads used by tarpmir to parallelize the processing of mRNA sequences for miRNA target prediction.", + "help_text": "Set the number of threads to be used for parallel processing. A higher number of threads will increase the speed but may consume more system resources. (default: 12)", + "default": 12 + }, "pita_lengths": { "type": "string", "fa_icon": "fas fa-wrench", From 3c4acc96435209f3a7ab8686f2a5a6070e715ce7 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Thu, 26 Sep 2024 15:27:43 +0200 Subject: [PATCH 38/53] adding missing ; --- modules/local/pita/templates/pita_prediction.pl | 6 +++--- 1 file changed, 3 insertions(+), 3 deletions(-) diff --git a/modules/local/pita/templates/pita_prediction.pl b/modules/local/pita/templates/pita_prediction.pl index 8de04b72..42a4356f 100755 --- a/modules/local/pita/templates/pita_prediction.pl +++ b/modules/local/pita/templates/pita_prediction.pl @@ -13,9 +13,9 @@ my \$mir_fn = '${mature}'; my \$flank_up = get_arg("flank_up", "", \\%args); my \$flank_down = get_arg("flank_down", "", \\%args); -my \$lengths = '${params.pita_lengths}' -my \$gu = '${params.pita_wobbles}' -my \$mismatches = '${params.pita_mismatches}' +my \$lengths = '${params.pita_lengths}'; +my \$gu = '${params.pita_wobbles}'; +my \$mismatches = '${params.pita_mismatches}'; my \$loop = get_arg("loop", "", \\%args); my \$gxp = get_arg("gxp", "", \\%args); From 533af26a91f7b0cd6f0eb6e64c171516d7c30cd3 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Mon, 30 Sep 2024 13:27:10 +0200 Subject: [PATCH 39/53] fixing output of pita --- modules/local/pita/main.nf | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/modules/local/pita/main.nf b/modules/local/pita/main.nf index f8358d35..447f42b4 100644 --- a/modules/local/pita/main.nf +++ b/modules/local/pita/main.nf @@ -12,8 +12,8 @@ process PITA { tuple val(meta2), path(mature) output: - tuple val(meta), path("*_pita_results.tab"), emit: tsv - path "versions.yml" , emit: versions + tuple val(meta), path("*.tab"), emit: tsv + path "versions.yml" , emit: versions when: task.ext.when == null || task.ext.when From f79c6f4268e3f9dbc2261d6d14cf4633076df93f Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Mon, 30 Sep 2024 13:27:34 +0200 Subject: [PATCH 40/53] adding versios.yml for pita_predict --- .../local/pita/templates/pita_prediction.pl | 29 ++++++++++++++++++- 1 file changed, 28 insertions(+), 1 deletion(-) diff --git a/modules/local/pita/templates/pita_prediction.pl b/modules/local/pita/templates/pita_prediction.pl index 42a4356f..241aab8e 100755 --- a/modules/local/pita/templates/pita_prediction.pl +++ b/modules/local/pita/templates/pita_prediction.pl @@ -7,7 +7,7 @@ my %args = load_args(\\@ARGV); -my \$prefix = 'circRNA'; +my \$prefix = '${meta.id}.pita'; my \$utr_fn = '${fasta}'; my \$upstream_fn = get_arg("upstream", "", \\%args); my \$mir_fn = '${mature}'; @@ -97,6 +97,33 @@ sub removeIllegalXMLChars return \$res_str; } +######################## +####### VERSIONS ####### +######################## + +# TODO: hardcoded for now, waiting for conda container +my \$viennarna_version = "1.6"; +my \$perl_version = "\$^V"; + +my \$str = <', \$filename) or die \$!; + +print FH \$str; + +close(FH); + +######################## +######################## +######################## + + __DATA__ syntax: pita_prediction.pl [OPTIONS] From f7141df3fbdc78250ee4c1cd4db2a7dff13ca8d6 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Mon, 30 Sep 2024 13:27:53 +0200 Subject: [PATCH 41/53] adding unify pita in conf --- conf/modules.config | 10 ++++++++++ 1 file changed, 10 insertions(+) diff --git a/conf/modules.config b/conf/modules.config index 12213309..73bdfb4f 100644 --- a/conf/modules.config +++ b/conf/modules.config @@ -828,6 +828,16 @@ process { saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, ] } + + withName: UNIFY_PITA { + ext.args = "-v FS='\\t' -v OFS='\\t' 'NR>1 { print \$2, \$1, \$3, \$4, \"pita\" }'" + ext.suffix = "pita.tsv" + publishDir = [ + path: { "${params.outdir}/mirna_prediction/binding_sites/tools/pita/unified" }, + mode: params.publish_dir_mode, + saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, + ] + } withName: COMBINE_BINDINGSITES { ext.prefix = "bindingsites.tsv" From 8412b1c4900001e3c97866035f4aa78e6d362fb9 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Mon, 30 Sep 2024 13:31:23 +0200 Subject: [PATCH 42/53] adding pita to mirna_bindingsites subworkflow --- subworkflows/local/mirna/mirna_bindingsites.nf | 15 ++++++++------- 1 file changed, 8 insertions(+), 7 deletions(-) diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index adea18db..e44a57df 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -1,5 +1,6 @@ include { BIOAWK as ADD_BACKSPLICE } from '../../../modules/nf-core/bioawk' include { GAWK as UNIFY_MIRANDA } from '../../../modules/nf-core/gawk' +include { GAWK as UNIFY_PITA } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARGETSCAN } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARPMIR } from '../../../modules/nf-core/gawk' include { MAJORITY_VOTE } from '../../../modules/local/majority_vote' @@ -66,8 +67,8 @@ workflow MIRNA_BINDINGSITES { // TARPMIR WORKFLOW: // - TARPMIR( ch_transcriptome_batches, mirna_fasta.collect() ) - UNIFY_TARPMIR( TARPMIR.out.bindings, [] ) + TARPMIR(ch_transcriptome_batches, mirna_fasta.collect()) + UNIFY_TARPMIR(TARPMIR.out.bindings, []) ch_versions = ch_versions.mix(TARPMIR.out.versions) ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) @@ -76,15 +77,15 @@ workflow MIRNA_BINDINGSITES { if (tools_selected.contains('pita')) { // - // TARPMIR WORKFLOW: + // PITA WORKFLOW: // - PITA( ch_transcriptome_batches, mirna_fasta.collect() ) - // UNIFY_TARPMIR( TARPMIR.out.bindings, [] ) + PITA(ch_transcriptome_batches, mirna_fasta.collect()) + UNIFY_PITA(PITA.out.tsv, []) ch_versions = ch_versions.mix(PITA.out.versions) - // ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) - // ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) + ch_versions = ch_versions.mix(UNIFY_PITA.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_PITA.out.output) } // From 8d0b8f268938ebda5b3efdab77a43594fb07f31a Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sun, 6 Oct 2024 12:13:17 +0200 Subject: [PATCH 43/53] formatting --- modules/local/pita/main.nf | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/modules/local/pita/main.nf b/modules/local/pita/main.nf index 447f42b4..b64d1951 100644 --- a/modules/local/pita/main.nf +++ b/modules/local/pita/main.nf @@ -13,7 +13,7 @@ process PITA { output: tuple val(meta), path("*.tab"), emit: tsv - path "versions.yml" , emit: versions + path "versions.yml", emit: versions when: task.ext.when == null || task.ext.when From 09b4d7efaf9518ab5057a07e66b43c52a99e2106 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sun, 6 Oct 2024 12:54:31 +0200 Subject: [PATCH 44/53] adjusting mirna tool filter param --- nextflow.config | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/nextflow.config b/nextflow.config index 051a7530..11fe52a2 100644 --- a/nextflow.config +++ b/nextflow.config @@ -86,7 +86,7 @@ params { mirna_min_reads = 5 mirna_min_sample_percentage = 0.2 mirna_tools = 'miranda,targetscan,tarpmir' - mirna_tool_filter = 1 + mirna_min_tools = 1 mirna_correlation = 'pearson' //> TARPMIR options From cb2afbacdfb2a4515560939e9110670db317e8d6 Mon Sep 17 00:00:00 2001 From: Malte Weyrich Date: Sun, 6 Oct 2024 12:56:32 +0200 Subject: [PATCH 45/53] removing outdated params --- nextflow_schema.json | 17 ----------------- 1 file changed, 17 deletions(-) diff --git a/nextflow_schema.json b/nextflow_schema.json index b20f9647..7d52b02e 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -173,23 +173,6 @@ "default": "pearson", "pattern": "^(pearson|spearman)$" }, - "mirna_tools": { - "type": "string", - "fa_icon": "fas fa-wrench", - "description": "Comma separated list of miRNA bindingsite prediction tools to use. Supported tools: miranda, targetscan.", - "help_text": "Select one or a combination of miRNA bindingsite prediction tools for the pipeline e.g:\n--mirna_tools 'miranda,targetscan'", - "default": "miranda,targetscan,tarpmir,pita", - "pattern": "^((miranda|targetscan|tarpmir,pita)?,?)*[^,]+$" - }, - "mirna_tool_filter": { - "type": "integer", - "fa_icon": "fas fa-intersection", - "description": "Specify the number of votes required for a miRNA to be further considered in downstream analysis.'", - "help_text": "Controls the number of votes required for a binding site prediction to be considered valid. If a miRNA binding site was predicted by two different tools (e.g., miRanda and TargetScan), it receives two votes. By specifying additional tools for miRNA binding site prediction (using the 'mirna_tool_filter' parameter), you can adjust the number of votes required for a binding site to be considered valid.", - "default": 1, - "minimum": 1, - "maximum": 4 - }, "tarpmir_cut": { "type": "number", "fa_icon": "fas fa-circle-notch", From 2e66b0637ad8b7ee7397fc0d780978205860bf7a Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Thu, 16 Jan 2025 09:50:25 +0100 Subject: [PATCH 46/53] Latest changes from Malte --- .../combinebeds/filter/templates/filter.py | 1 + .../main.nf | 4 +- .../templates/gene_deseq_normalization.R} | 0 modules/local/majority_vote/main.nf | 4 +- .../local/majority_vote/templates/majority.py | 16 ++- modules/local/sponge/main.nf | 4 +- modules/local/sponge/templates/sponge.R | 17 +-- modules/local/tarpmir/main.nf | 5 +- .../tarpmir/templates/TarPmiR_threading.py | 2 +- nextflow.config | 2 +- .../local/mirna/mirna_bindingsites.nf | 109 ++++++++++-------- subworkflows/local/mirna_prediction.nf | 33 +++--- subworkflows/local/quantification.nf | 1 + workflows/circrna/main.nf | 2 +- 14 files changed, 106 insertions(+), 94 deletions(-) rename modules/local/deseq2/{tx_normalization => gene_normalization}/main.nf (92%) rename modules/local/deseq2/{tx_normalization/templates/tx_deseq_normalization.R => gene_normalization/templates/gene_deseq_normalization.R} (100%) diff --git a/modules/local/combinebeds/filter/templates/filter.py b/modules/local/combinebeds/filter/templates/filter.py index be352590..a2999121 100644 --- a/modules/local/combinebeds/filter/templates/filter.py +++ b/modules/local/combinebeds/filter/templates/filter.py @@ -74,6 +74,7 @@ def format_yaml_like(data: dict, indent: int = 0) -> str: continue memberships = series.to_list() dataset = upsetplot.from_memberships(memberships) + # TODO: Make this more robust for large datasets upsetplot.plot(dataset, orientation='horizontal', show_counts=True, diff --git a/modules/local/deseq2/tx_normalization/main.nf b/modules/local/deseq2/gene_normalization/main.nf similarity index 92% rename from modules/local/deseq2/tx_normalization/main.nf rename to modules/local/deseq2/gene_normalization/main.nf index 6f322e16..390a042d 100644 --- a/modules/local/deseq2/tx_normalization/main.nf +++ b/modules/local/deseq2/gene_normalization/main.nf @@ -1,4 +1,4 @@ -process TX_NORMALIZATION { +process GENE_NORMALIZATION { tag "$meta.id" label 'process_single' @@ -18,7 +18,7 @@ process TX_NORMALIZATION { task.ext.when == null || task.ext.when script: - template 'tx_deseq_normalization.R' + template 'gene_deseq_normalization.R' stub: """ diff --git a/modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R b/modules/local/deseq2/gene_normalization/templates/gene_deseq_normalization.R similarity index 100% rename from modules/local/deseq2/tx_normalization/templates/tx_deseq_normalization.R rename to modules/local/deseq2/gene_normalization/templates/gene_deseq_normalization.R diff --git a/modules/local/majority_vote/main.nf b/modules/local/majority_vote/main.nf index c77ecb0f..48bbeea6 100644 --- a/modules/local/majority_vote/main.nf +++ b/modules/local/majority_vote/main.nf @@ -1,6 +1,6 @@ process MAJORITY_VOTE { tag "$meta.id" - label 'process_medium' + label 'process_high' conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? @@ -13,7 +13,6 @@ process MAJORITY_VOTE { output: tuple val(meta), path("${meta.id}.majority.tsv") , emit: tsv tuple val(meta), path("${meta.id}.targets.tsv") , emit: targets - tuple val(meta), path("${meta.id}.binding_sites.tsv") , emit: binding_sites path "versions.yml" , emit: versions when: @@ -26,6 +25,7 @@ process MAJORITY_VOTE { stub: """ touch ${meta.id}.majority.tsv + touch ${meta.id}.targets.tsv cat <<-END_VERSIONS > versions.yml "${task.process}": diff --git a/modules/local/majority_vote/templates/majority.py b/modules/local/majority_vote/templates/majority.py index 2869cb37..e47c5e08 100644 --- a/modules/local/majority_vote/templates/majority.py +++ b/modules/local/majority_vote/templates/majority.py @@ -3,7 +3,18 @@ import polars as pl import yaml -paths = "${bindingsites}".split(" ") +# paths = "${bindingsites}".split(" ") +paths = [] +bindingsites = "${bindingsites}" + +j = 0 +for i in range(len(bindingsites)): + if bindingsites[i] == " " or i == len(bindingsites) - 1: + paths.append(bindingsites[j : i + 1]) + j = i + 1 + +print(paths[1:3]) +print(len(paths)) df = pl.scan_csv(paths, separator="\\t", @@ -14,7 +25,7 @@ df = df.group_by(['mirna', 'target']).agg(pl.col("tool").n_unique()) -df = df.filter(pl.col("tool") > int("${min_tools}")) \ +df = df.filter(pl.col("tool") >= int("${min_tools}")) \ .select(["mirna", "target"]) df = df.collect() @@ -37,3 +48,4 @@ with open("versions.yml", "w") as f: f.write(yaml.dump(versions)) + diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/main.nf index 071d500a..f7aac8f4 100644 --- a/modules/local/sponge/main.nf +++ b/modules/local/sponge/main.nf @@ -4,8 +4,8 @@ process SPONGE { conda "${moduleDir}/environment.yml" container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ? - 'oras://community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:086ecad7b1034ff0' : - 'community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:e79cb4c59aecf7ba' }" + 'oras://community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:b65c26ac28f443f5' : + 'community.wave.seqera.io/library/bioconductor-sponge_r-doparallel_r-foreach_r-visnetwork:44865af735ff0e33' }" input: tuple val(meta), path(binding_sites) diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/templates/sponge.R index 8d42276a..025e17d6 100644 --- a/modules/local/sponge/templates/sponge.R +++ b/modules/local/sponge/templates/sponge.R @@ -13,11 +13,9 @@ circ_mRNA_subnetwork <- function(interactions, pattern) { } # load binding sites matrix -bindingsites <- read.table("${binding_sites}", sep = "\\t", header = TRUE, check.names = FALSE) -rownames(bindingsites) <- bindingsites[, 1] -bindingsites <- bindingsites[, -1] -bindingsites_matrix <- as.matrix(bindingsites) - +bindingsites <- read.table("${binding_sites}", sep = "\t", header = FALSE, col.names = c("mirna", "gene")) +bindingsites_matrix <- table(bindingsites[, 2], bindingsites[, 1]) +bindingsites_matrix[bindingsites_matrix > 0] <- 1 # load gene expression genes <- read.csv("${gene_expr}", sep = "\\t", row.names = "tx") @@ -52,16 +50,9 @@ gene_expriRNA_candidates <- SPONGE::sponge_gene_miRNA_interaction_filter( gene_expr = gene_expr, mir_expr = mir_expr, mir_predicted_targets = bindingsites_matrix, - F.test = FALSE, - coefficient.threshold = -0.01, - coefficient.direction = NULL + coefficient.threshold = -0.001 ) - - # F.test.p.adj.threshold = ${params.sponge_f_test_pval}, - # coefficient.threshold = ${params.sponge_coeff_threshold}, - # elastic.net = ("${params.sponge_elastic_net}" == "true") - ###################################### # B # ###################################### diff --git a/modules/local/tarpmir/main.nf b/modules/local/tarpmir/main.nf index 08f70a6c..6fbe6761 100644 --- a/modules/local/tarpmir/main.nf +++ b/modules/local/tarpmir/main.nf @@ -12,14 +12,13 @@ process TARPMIR { tuple val(meta2), path(mature) output: - tuple val(meta), path("${prefix}.bindings.bp"), emit: bindings - path "versions.yml" , emit: versions + tuple val(meta), path("*.bindings.bp"), emit: bindings + path "versions.yml" , emit: versions when: task.ext.when == null || task.ext.when script: - prefix = task.ext.prefix ?: "${meta.id}" template 'TarPmiR_threading.py' stub: diff --git a/modules/local/tarpmir/templates/TarPmiR_threading.py b/modules/local/tarpmir/templates/TarPmiR_threading.py index 8955094b..f2411017 100644 --- a/modules/local/tarpmir/templates/TarPmiR_threading.py +++ b/modules/local/tarpmir/templates/TarPmiR_threading.py @@ -659,7 +659,7 @@ def main(): mode_path="${moduleDir}/Human_sklearn_0.22.pkl" pb_cut=float(${params.tarpmir_cut}) n_threads_input=${params.tarpmir_threads} - output_file="${meta.id}.bindings.tsv" + output_file="${meta.id}.bindings.bp" global sessionID sessionID= 'fn_'+str(uuid.uuid1()) diff --git a/nextflow.config b/nextflow.config index 11fe52a2..5fa57cc7 100644 --- a/nextflow.config +++ b/nextflow.config @@ -86,7 +86,7 @@ params { mirna_min_reads = 5 mirna_min_sample_percentage = 0.2 mirna_tools = 'miranda,targetscan,tarpmir' - mirna_min_tools = 1 + mirna_min_tools = 1 mirna_correlation = 'pearson' //> TARPMIR options diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index e44a57df..35d90421 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -38,55 +38,56 @@ workflow MIRNA_BINDINGSITES { error 'No tools selected for miRNA discovery.' } - if (tools_selected.contains('targetscan')) { - // - // TARGETSCAN WORKFLOW: - // - TARGETSCAN( ch_transcriptome_batches, formatMiRNAForTargetScan( mirna_fasta ).collect() ) - UNIFY_TARGETSCAN( TARGETSCAN.out.txt, [] ) - - ch_versions = ch_versions.mix(TARGETSCAN.out.versions) - ch_versions = ch_versions.mix(UNIFY_TARGETSCAN.out.versions) - ch_predictions = ch_predictions.mix(UNIFY_TARGETSCAN.out.output) - } - - if (tools_selected.contains('miranda')) { - // - // MIRANDA WORKFLOW: - // - MIRANDA( ch_transcriptome_batches, mirna_fasta.map{meta, mature -> mature}.collect() ) - UNIFY_MIRANDA( MIRANDA.out.txt, [] ) - - ch_versions = ch_versions.mix(MIRANDA.out.versions) - ch_versions = ch_versions.mix(UNIFY_MIRANDA.out.versions) - ch_predictions = ch_predictions.mix(UNIFY_MIRANDA.out.output) - } - - if (tools_selected.contains('tarpmir')) { - // - // TARPMIR WORKFLOW: - // - - TARPMIR(ch_transcriptome_batches, mirna_fasta.collect()) - UNIFY_TARPMIR(TARPMIR.out.bindings, []) - - ch_versions = ch_versions.mix(TARPMIR.out.versions) - ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) - ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) - } - - if (tools_selected.contains('pita')) { - // - // PITA WORKFLOW: - // - - PITA(ch_transcriptome_batches, mirna_fasta.collect()) - UNIFY_PITA(PITA.out.tsv, []) - - ch_versions = ch_versions.mix(PITA.out.versions) - ch_versions = ch_versions.mix(UNIFY_PITA.out.versions) - ch_predictions = ch_predictions.mix(UNIFY_PITA.out.output) - } + // TODO: uncomment next time + // if (tools_selected.contains('targetscan')) { + // // + // // TARGETSCAN WORKFLOW: + // // + // TARGETSCAN( ch_transcriptome_batches, formatMiRNAForTargetScan( mirna_fasta ).collect() ) + // UNIFY_TARGETSCAN( TARGETSCAN.out.txt, [] ) + + // ch_versions = ch_versions.mix(TARGETSCAN.out.versions) + // ch_versions = ch_versions.mix(UNIFY_TARGETSCAN.out.versions) + // ch_predictions = ch_predictions.mix(UNIFY_TARGETSCAN.out.output) + // } + + // if (tools_selected.contains('miranda')) { + // // + // // MIRANDA WORKFLOW: + // // + // MIRANDA( ch_transcriptome_batches, mirna_fasta.map{meta, mature -> mature}.collect() ) + // UNIFY_MIRANDA( MIRANDA.out.txt, [] ) + + // ch_versions = ch_versions.mix(MIRANDA.out.versions) + // ch_versions = ch_versions.mix(UNIFY_MIRANDA.out.versions) + // ch_predictions = ch_predictions.mix(UNIFY_MIRANDA.out.output) + // } + + // if (tools_selected.contains('tarpmir')) { + // // + // // TARPMIR WORKFLOW: + // // + + // TARPMIR(ch_transcriptome_batches, mirna_fasta.collect()) + // UNIFY_TARPMIR(TARPMIR.out.bindings, []) + + // ch_versions = ch_versions.mix(TARPMIR.out.versions) + // ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) + // ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) + // } + + // if (tools_selected.contains('pita')) { + // // + // // PITA WORKFLOW: + // // + + // PITA(ch_transcriptome_batches, mirna_fasta.collect()) + // UNIFY_PITA(PITA.out.tsv, []) + + // ch_versions = ch_versions.mix(PITA.out.versions) + // ch_versions = ch_versions.mix(UNIFY_PITA.out.versions) + // ch_predictions = ch_predictions.mix(UNIFY_PITA.out.output) + // } // // CONSOLIDATE PREDICTIONS WORKFLOW: @@ -102,12 +103,18 @@ workflow MIRNA_BINDINGSITES { // // MAJORITY VOTING: // - MAJORITY_VOTE( ch_predictions.map{meta, file -> file}.collect().map{[[id: "mirna"], it]} ) + + // TODO: uncomment next time + // ch_combined_predictions = ch_predictions.map{meta, file -> file}.collect().map{[[id: "mirna"], it]}.collect() + + ch_combined_predictions = Channel.fromPath('/nfs/home/students/mweyrich/tool.paths').splitText().collectFile().flatMap { it.text.split(/\s+/) }.collect().map{[[id: "mirna"], it]}.collect() + + MAJORITY_VOTE(ch_combined_predictions) ch_versions = ch_versions.mix(MAJORITY_VOTE.out.versions) emit: targets = MAJORITY_VOTE.out.targets - binding_sites = MAJORITY_VOTE.out.binding_sites + binding_sites = MAJORITY_VOTE.out.tsv versions = ch_versions } diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index 3c47df47..2684cc39 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -1,7 +1,7 @@ // MODULES include { BIOAWK as ADD_BACKSPLICE } from '../../modules/nf-core/bioawk' include { MIRNA_NORMALIZATION } from '../../modules/local/deseq2/mirna_normalization' -include { TX_NORMALIZATION } from '../../modules/local/deseq2/tx_normalization' +include { GENE_NORMALIZATION } from '../../modules/local/deseq2/gene_normalization' include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' include { SPONGE } from '../../modules/local/sponge' @@ -17,8 +17,8 @@ workflow MIRNA_PREDICTION { circrna_annotation ch_mature ch_mirna - quantification_rds tx_counts + quantification_rds main: ch_versions = Channel.empty() @@ -69,34 +69,35 @@ workflow MIRNA_PREDICTION { // // COMPUTE CORRELATION: // - ch_binding_site_batches = MIRNA_BINDINGSITES.out.targets - .splitText(by: 100, file: true) - .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} + // TODO: uncomment + // ch_binding_site_batches = MIRNA_BINDINGSITES.out.targets + // .splitText(by: 100, file: true) + // .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} - COMPUTE_CORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) + // COMPUTE_CORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) - ch_correlation_results = COMPUTE_CORRELATIONS.out.correlations - .map{meta, results -> results} - .flatten().collect() - .map{results -> [[id: 'correlation'], results]} + // ch_correlation_results = COMPUTE_CORRELATIONS.out.correlations + // .map{meta, results -> results} + // .flatten().collect() + // .map{results -> [[id: 'correlation'], results]} - ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) + // ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) } // if (params.sponge) - ch_tx_normalized = TX_NORMALIZATION(tx_counts).normalized + ch_gene_normalized = GENE_NORMALIZATION(tx_counts).normalized - ch_versions = ch_versions.mix(TX_NORMALIZATION.out.versions) + ch_versions = ch_versions.mix(GENE_NORMALIZATION.out.versions) - SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_tx_normalized, ch_mirna_filtered) + SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_gene_normalized, ch_mirna_filtered) ch_versions = ch_versions.mix(SPONGE.out.versions) - SPONGE_EFFECTS(SPONGE.out.sponge_data) + // SPONGE_EFFECTS(SPONGE.out.sponge_data) - ch_versions = ch_versions.mix(SPONGE_EFFECTS.out.versions) + // ch_versions = ch_versions.mix(SPONGE_EFFECTS.out.versions) emit: versions = ch_versions diff --git a/subworkflows/local/quantification.nf b/subworkflows/local/quantification.nf index a5540a81..afd8a1ba 100644 --- a/subworkflows/local/quantification.nf +++ b/subworkflows/local/quantification.nf @@ -86,6 +86,7 @@ workflow QUANTIFICATION { ciriquant = ch_ciriquant stringtie = ch_stringtie rds = ch_rds + tx = PSIRC_QUANT.out.tx_counts versions = ch_versions } diff --git a/workflows/circrna/main.nf b/workflows/circrna/main.nf index 0da695ff..7a8d8d3a 100644 --- a/workflows/circrna/main.nf +++ b/workflows/circrna/main.nf @@ -176,7 +176,7 @@ workflow CIRCRNA { BSJ_DETECTION.out.bed12, ch_mature, ch_mirna, - QUANTIFICATION.out.tx_counts, + QUANTIFICATION.out.tx, QUANTIFICATION.out.rds ) ch_versions = ch_versions.mix(MIRNA_PREDICTION.out.versions) From d1525e7293c4d27c60956bf9698c398e7e8690eb Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Thu, 16 Jan 2025 11:28:26 +0100 Subject: [PATCH 47/53] Re-enable everything in mirna_bindingsites subworkflow --- .../local/mirna/mirna_bindingsites.nf | 110 +++++++++--------- 1 file changed, 53 insertions(+), 57 deletions(-) diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index 35d90421..bc128baf 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -38,76 +38,72 @@ workflow MIRNA_BINDINGSITES { error 'No tools selected for miRNA discovery.' } - // TODO: uncomment next time - // if (tools_selected.contains('targetscan')) { - // // - // // TARGETSCAN WORKFLOW: - // // - // TARGETSCAN( ch_transcriptome_batches, formatMiRNAForTargetScan( mirna_fasta ).collect() ) - // UNIFY_TARGETSCAN( TARGETSCAN.out.txt, [] ) - - // ch_versions = ch_versions.mix(TARGETSCAN.out.versions) - // ch_versions = ch_versions.mix(UNIFY_TARGETSCAN.out.versions) - // ch_predictions = ch_predictions.mix(UNIFY_TARGETSCAN.out.output) - // } - - // if (tools_selected.contains('miranda')) { - // // - // // MIRANDA WORKFLOW: - // // - // MIRANDA( ch_transcriptome_batches, mirna_fasta.map{meta, mature -> mature}.collect() ) - // UNIFY_MIRANDA( MIRANDA.out.txt, [] ) - - // ch_versions = ch_versions.mix(MIRANDA.out.versions) - // ch_versions = ch_versions.mix(UNIFY_MIRANDA.out.versions) - // ch_predictions = ch_predictions.mix(UNIFY_MIRANDA.out.output) - // } - - // if (tools_selected.contains('tarpmir')) { - // // - // // TARPMIR WORKFLOW: - // // - - // TARPMIR(ch_transcriptome_batches, mirna_fasta.collect()) - // UNIFY_TARPMIR(TARPMIR.out.bindings, []) - - // ch_versions = ch_versions.mix(TARPMIR.out.versions) - // ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) - // ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) - // } - - // if (tools_selected.contains('pita')) { - // // - // // PITA WORKFLOW: - // // - - // PITA(ch_transcriptome_batches, mirna_fasta.collect()) - // UNIFY_PITA(PITA.out.tsv, []) - - // ch_versions = ch_versions.mix(PITA.out.versions) - // ch_versions = ch_versions.mix(UNIFY_PITA.out.versions) - // ch_predictions = ch_predictions.mix(UNIFY_PITA.out.output) - // } + if (tools_selected.contains('targetscan')) { + // + // TARGETSCAN WORKFLOW: + // + TARGETSCAN( ch_transcriptome_batches, formatMiRNAForTargetScan( mirna_fasta ).collect() ) + UNIFY_TARGETSCAN( TARGETSCAN.out.txt, [] ) + + ch_versions = ch_versions.mix(TARGETSCAN.out.versions) + ch_versions = ch_versions.mix(UNIFY_TARGETSCAN.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_TARGETSCAN.out.output) + } + + if (tools_selected.contains('miranda')) { + // + // MIRANDA WORKFLOW: + // + MIRANDA( ch_transcriptome_batches, mirna_fasta.map{meta, mature -> mature}.collect() ) + UNIFY_MIRANDA( MIRANDA.out.txt, [] ) + + ch_versions = ch_versions.mix(MIRANDA.out.versions) + ch_versions = ch_versions.mix(UNIFY_MIRANDA.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_MIRANDA.out.output) + } + + if (tools_selected.contains('tarpmir')) { + // + // TARPMIR WORKFLOW: + // + + TARPMIR(ch_transcriptome_batches, mirna_fasta.collect()) + UNIFY_TARPMIR(TARPMIR.out.bindings, []) + + ch_versions = ch_versions.mix(TARPMIR.out.versions) + ch_versions = ch_versions.mix(UNIFY_TARPMIR.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_TARPMIR.out.output) + } + + if (tools_selected.contains('pita')) { + // + // PITA WORKFLOW: + // + + PITA(ch_transcriptome_batches, mirna_fasta.collect()) + UNIFY_PITA(PITA.out.tsv, []) + + ch_versions = ch_versions.mix(PITA.out.versions) + ch_versions = ch_versions.mix(UNIFY_PITA.out.versions) + ch_predictions = ch_predictions.mix(UNIFY_PITA.out.output) + } // // CONSOLIDATE PREDICTIONS WORKFLOW: // // TODO: This is an artifact and should be removed if we have a replacement - // consolidate_targets = TARGETSCAN.out.txt.join(MIRANDA.out.txt) + consolidate_targets = TARGETSCAN.out.txt.join(MIRANDA.out.txt) - // MIRNA_TARGETS( consolidate_targets ) + MIRNA_TARGETS( consolidate_targets ) - // ch_versions = ch_versions.mix(MIRNA_TARGETS.out.versions) + ch_versions = ch_versions.mix(MIRNA_TARGETS.out.versions) // // MAJORITY VOTING: // - // TODO: uncomment next time - // ch_combined_predictions = ch_predictions.map{meta, file -> file}.collect().map{[[id: "mirna"], it]}.collect() - - ch_combined_predictions = Channel.fromPath('/nfs/home/students/mweyrich/tool.paths').splitText().collectFile().flatMap { it.text.split(/\s+/) }.collect().map{[[id: "mirna"], it]}.collect() + ch_combined_predictions = ch_predictions.map{meta, file -> file}.collect().map{[[id: "mirna"], it]}.collect() MAJORITY_VOTE(ch_combined_predictions) ch_versions = ch_versions.mix(MAJORITY_VOTE.out.versions) From 2075095f035f9b6a1992f046c0dbb6f203c9fa32 Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Thu, 16 Jan 2025 23:36:24 +0100 Subject: [PATCH 48/53] Improve mirna majority vote script --- .../local/majority_vote/templates/majority.py | 32 +++++-------------- 1 file changed, 8 insertions(+), 24 deletions(-) diff --git a/modules/local/majority_vote/templates/majority.py b/modules/local/majority_vote/templates/majority.py index e47c5e08..f8940bcd 100644 --- a/modules/local/majority_vote/templates/majority.py +++ b/modules/local/majority_vote/templates/majority.py @@ -3,39 +3,23 @@ import polars as pl import yaml -# paths = "${bindingsites}".split(" ") -paths = [] -bindingsites = "${bindingsites}" +df = pl.scan_csv("*.tsv", + separator="\\t", + has_header=False, + new_columns=['mirna', 'target', 'start', 'end', 'tool']) -j = 0 -for i in range(len(bindingsites)): - if bindingsites[i] == " " or i == len(bindingsites) - 1: - paths.append(bindingsites[j : i + 1]) - j = i + 1 +df = df.select("mirna", "target", "tool") +df = df.group_by('mirna', 'target').agg(pl.col("tool").n_unique()) -print(paths[1:3]) -print(len(paths)) - -df = pl.scan_csv(paths, - separator="\\t", - has_header=False, - new_columns=['mirna', 'target', 'start', 'end', 'tool']) - -df = df.select(["mirna", "target", "tool"]) - -df = df.group_by(['mirna', 'target']).agg(pl.col("tool").n_unique()) - -df = df.filter(pl.col("tool") >= int("${min_tools}")) \ - .select(["mirna", "target"]) +df = df.filter(pl.col("tool") >= int("${min_tools}")) +df = df.select("mirna", "target") df = df.collect() - df.write_csv('${meta.id}.majority.tsv', separator='\\t', include_header=False) # Create targets file df = df.group_by('mirna').agg(pl.col("target").str.concat(",")) - df.write_csv('${meta.id}.targets.tsv', separator='\\t', include_header=False) # Create version file From bc7b7dec0f1e95e5fcd5d9b04067ae78d8acb62f Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Fri, 17 Jan 2025 00:01:34 +0100 Subject: [PATCH 49/53] Improve SPONGE script --- modules/local/sponge/templates/sponge.R | 5 ++++- 1 file changed, 4 insertions(+), 1 deletion(-) diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/templates/sponge.R index 025e17d6..2ae00805 100644 --- a/modules/local/sponge/templates/sponge.R +++ b/modules/local/sponge/templates/sponge.R @@ -67,9 +67,12 @@ ceRNA_interactions <- SPONGE::sponge( # C # ###################################### +n_samples <- nrow(gene_expr) + mscor_null_model <- SPONGE::sponge_build_null_model( number_of_datasets = 100, - number_of_samples = nrow(gene_expr) + number_of_samples = n_samples, + m_max = min(8, n_samples - 4) # Reconstructed based on https://github.com/daisybio/SPONGE/blob/d2592800cd2b72b92fe59aba2183f1dffcac3465/R/fn_significance.R#L253 ) sim_plot <- SPONGE::sponge_plot_simulation_results(mscor_null_model) From 705f2f4b97d22ed9b4c104e0b03757eefab0515c Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Fri, 17 Jan 2025 00:11:58 +0100 Subject: [PATCH 50/53] Re-enable commented-out sections from mirna prediction --- subworkflows/local/mirna_prediction.nf | 49 ++++++++++++-------------- 1 file changed, 23 insertions(+), 26 deletions(-) diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index 2684cc39..0be16b8c 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -24,7 +24,7 @@ workflow MIRNA_PREDICTION { ch_versions = Channel.empty() // - // MIRNA NORMALIZATION WORKFLOW: + // MIRNA NORMALIZATION WORKFLOW // if (params.mirna_expression) { @@ -41,7 +41,7 @@ workflow MIRNA_PREDICTION { ch_versions = ch_versions.mix(MIRNA_FILTERING.out.versions) // - // MIRNA BINDING SITES: + // MIRNA BINDING SITES // // Filtering miRNAs from ch_mature if they are not in ch_mirna_filtered. @@ -66,38 +66,35 @@ workflow MIRNA_PREDICTION { ch_versions = ch_versions.mix(MIRNA_BINDINGSITES.out.versions) if (params.mirna_expression) { + // - // COMPUTE CORRELATION: + // COMPUTE CORRELATION // - // TODO: uncomment - // ch_binding_site_batches = MIRNA_BINDINGSITES.out.targets - // .splitText(by: 100, file: true) - // .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} - - // COMPUTE_CORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) - - // ch_correlation_results = COMPUTE_CORRELATIONS.out.correlations - // .map{meta, results -> results} - // .flatten().collect() - // .map{results -> [[id: 'correlation'], results]} - - // ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) - } + ch_binding_site_batches = MIRNA_BINDINGSITES.out.targets + .splitText(by: 100, file: true) + .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} - // if (params.sponge) + COMPUTE_CORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) + ch_correlation_results = COMPUTE_CORRELATIONS.out.correlations + .map{meta, results -> results} + .flatten().collect() + .map{results -> [[id: 'correlation'], results]} - ch_gene_normalized = GENE_NORMALIZATION(tx_counts).normalized + ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) - ch_versions = ch_versions.mix(GENE_NORMALIZATION.out.versions) - - SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_gene_normalized, ch_mirna_filtered) - - ch_versions = ch_versions.mix(SPONGE.out.versions) + // + // SPONGE + // + ch_gene_normalized = GENE_NORMALIZATION(tx_counts).normalized + ch_versions = ch_versions.mix(GENE_NORMALIZATION.out.versions) - // SPONGE_EFFECTS(SPONGE.out.sponge_data) + SPONGE(MIRNA_BINDINGSITES.out.binding_sites, ch_gene_normalized, ch_mirna_filtered) + ch_versions = ch_versions.mix(SPONGE.out.versions) - // ch_versions = ch_versions.mix(SPONGE_EFFECTS.out.versions) + SPONGE_EFFECTS(SPONGE.out.sponge_data) + ch_versions = ch_versions.mix(SPONGE_EFFECTS.out.versions) + } emit: versions = ch_versions From 7b93466dc147a01a9ae7e2ff5a76a8037cc83d62 Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Sun, 19 Jan 2025 11:16:01 +0100 Subject: [PATCH 51/53] Improve mirna module structure --- conf/modules.config | 8 ++++---- .../computecorrelations}/environment.yml | 0 .../computecorrelations}/main.nf | 2 +- .../templates/compute_correlations.R | 0 .../{mirna_filtering => mirna/filtering}/main.nf | 0 .../filtering}/templates/mirna_filtering.R | 0 .../majorityvote}/environment.yml | 0 .../{majority_vote => mirna/majorityvote}/main.nf | 2 +- .../majorityvote}/templates/majority.py | 0 .../local/{mirna_targets => mirna/targets}/main.nf | 0 modules/local/sponge/{ => sponge}/main.nf | 2 +- .../local/sponge/{ => sponge}/templates/sponge.R | 0 .../spongeffects}/main.nf | 2 +- .../spongeffects}/templates/sponge_effects.R | 0 subworkflows/local/mirna/mirna_bindingsites.nf | 12 ++++++------ subworkflows/local/mirna_prediction.nf | 14 +++++++------- 16 files changed, 21 insertions(+), 21 deletions(-) rename modules/local/{compute_correlations => mirna/computecorrelations}/environment.yml (100%) rename modules/local/{compute_correlations => mirna/computecorrelations}/main.nf (95%) rename modules/local/{compute_correlations => mirna/computecorrelations}/templates/compute_correlations.R (100%) rename modules/local/{mirna_filtering => mirna/filtering}/main.nf (100%) rename modules/local/{mirna_filtering => mirna/filtering}/templates/mirna_filtering.R (100%) rename modules/local/{majority_vote => mirna/majorityvote}/environment.yml (100%) rename modules/local/{majority_vote => mirna/majorityvote}/main.nf (97%) rename modules/local/{majority_vote => mirna/majorityvote}/templates/majority.py (100%) rename modules/local/{mirna_targets => mirna/targets}/main.nf (100%) rename modules/local/sponge/{ => sponge}/main.nf (98%) rename modules/local/sponge/{ => sponge}/templates/sponge.R (100%) rename modules/local/{sponge_effects => sponge/spongeffects}/main.nf (98%) rename modules/local/{sponge_effects => sponge/spongeffects}/templates/sponge_effects.R (100%) diff --git a/conf/modules.config b/conf/modules.config index 73bdfb4f..70a8ceca 100644 --- a/conf/modules.config +++ b/conf/modules.config @@ -828,7 +828,7 @@ process { saveAs: { filename -> filename.equals('versions.yml') ? null : filename }, ] } - + withName: UNIFY_PITA { ext.args = "-v FS='\\t' -v OFS='\\t' 'NR>1 { print \$2, \$1, \$3, \$4, \"pita\" }'" ext.suffix = "pita.tsv" @@ -1071,7 +1071,7 @@ process { pattern: "*.bp" ] } - + withName: PITA { ext.prefix = { "${meta.id}.pita" } publishDir = [ @@ -1099,7 +1099,7 @@ process { ] } - withName: MAJORITY_VOTE { + withName: MIRNA_MAJORITYVOTE { publishDir = [ path: { "${params.outdir}/mirna_prediction/binding_sites/majority_vote" }, mode: params.publish_dir_mode, @@ -1107,7 +1107,7 @@ process { ] } - withName: '.*:MIRNA_PREDICTION:COMPUTE_CORRELATIONS' { + withName: '.*:MIRNA_PREDICTION:MIRNA_COMPUTECORRELATIONS' { publishDir = [ path: { "${params.outdir}/mirna_prediction/correlation" }, mode: params.publish_dir_mode, diff --git a/modules/local/compute_correlations/environment.yml b/modules/local/mirna/computecorrelations/environment.yml similarity index 100% rename from modules/local/compute_correlations/environment.yml rename to modules/local/mirna/computecorrelations/environment.yml diff --git a/modules/local/compute_correlations/main.nf b/modules/local/mirna/computecorrelations/main.nf similarity index 95% rename from modules/local/compute_correlations/main.nf rename to modules/local/mirna/computecorrelations/main.nf index 4a72b5eb..b44b8fd4 100644 --- a/modules/local/compute_correlations/main.nf +++ b/modules/local/mirna/computecorrelations/main.nf @@ -1,4 +1,4 @@ -process COMPUTE_CORRELATIONS { +process MIRNA_COMPUTECORRELATIONS { tag "$meta.id" label 'process_single' diff --git a/modules/local/compute_correlations/templates/compute_correlations.R b/modules/local/mirna/computecorrelations/templates/compute_correlations.R similarity index 100% rename from modules/local/compute_correlations/templates/compute_correlations.R rename to modules/local/mirna/computecorrelations/templates/compute_correlations.R diff --git a/modules/local/mirna_filtering/main.nf b/modules/local/mirna/filtering/main.nf similarity index 100% rename from modules/local/mirna_filtering/main.nf rename to modules/local/mirna/filtering/main.nf diff --git a/modules/local/mirna_filtering/templates/mirna_filtering.R b/modules/local/mirna/filtering/templates/mirna_filtering.R similarity index 100% rename from modules/local/mirna_filtering/templates/mirna_filtering.R rename to modules/local/mirna/filtering/templates/mirna_filtering.R diff --git a/modules/local/majority_vote/environment.yml b/modules/local/mirna/majorityvote/environment.yml similarity index 100% rename from modules/local/majority_vote/environment.yml rename to modules/local/mirna/majorityvote/environment.yml diff --git a/modules/local/majority_vote/main.nf b/modules/local/mirna/majorityvote/main.nf similarity index 97% rename from modules/local/majority_vote/main.nf rename to modules/local/mirna/majorityvote/main.nf index 48bbeea6..241c59f5 100644 --- a/modules/local/majority_vote/main.nf +++ b/modules/local/mirna/majorityvote/main.nf @@ -1,4 +1,4 @@ -process MAJORITY_VOTE { +process MIRNA_MAJORITYVOTE { tag "$meta.id" label 'process_high' diff --git a/modules/local/majority_vote/templates/majority.py b/modules/local/mirna/majorityvote/templates/majority.py similarity index 100% rename from modules/local/majority_vote/templates/majority.py rename to modules/local/mirna/majorityvote/templates/majority.py diff --git a/modules/local/mirna_targets/main.nf b/modules/local/mirna/targets/main.nf similarity index 100% rename from modules/local/mirna_targets/main.nf rename to modules/local/mirna/targets/main.nf diff --git a/modules/local/sponge/main.nf b/modules/local/sponge/sponge/main.nf similarity index 98% rename from modules/local/sponge/main.nf rename to modules/local/sponge/sponge/main.nf index f7aac8f4..2cf4c1d9 100644 --- a/modules/local/sponge/main.nf +++ b/modules/local/sponge/sponge/main.nf @@ -1,4 +1,4 @@ -process SPONGE { +process SPONGE_SPONGE { tag "$meta.id" label 'process_high' diff --git a/modules/local/sponge/templates/sponge.R b/modules/local/sponge/sponge/templates/sponge.R similarity index 100% rename from modules/local/sponge/templates/sponge.R rename to modules/local/sponge/sponge/templates/sponge.R diff --git a/modules/local/sponge_effects/main.nf b/modules/local/sponge/spongeffects/main.nf similarity index 98% rename from modules/local/sponge_effects/main.nf rename to modules/local/sponge/spongeffects/main.nf index 933fce8a..3e477092 100644 --- a/modules/local/sponge_effects/main.nf +++ b/modules/local/sponge/spongeffects/main.nf @@ -1,4 +1,4 @@ -process SPONGE_EFFECTS { +process SPONGE_SPONGEFFECTS { tag "$meta.id" label 'process_high' diff --git a/modules/local/sponge_effects/templates/sponge_effects.R b/modules/local/sponge/spongeffects/templates/sponge_effects.R similarity index 100% rename from modules/local/sponge_effects/templates/sponge_effects.R rename to modules/local/sponge/spongeffects/templates/sponge_effects.R diff --git a/subworkflows/local/mirna/mirna_bindingsites.nf b/subworkflows/local/mirna/mirna_bindingsites.nf index bc128baf..37acef94 100644 --- a/subworkflows/local/mirna/mirna_bindingsites.nf +++ b/subworkflows/local/mirna/mirna_bindingsites.nf @@ -3,9 +3,9 @@ include { GAWK as UNIFY_MIRANDA } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_PITA } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARGETSCAN } from '../../../modules/nf-core/gawk' include { GAWK as UNIFY_TARPMIR } from '../../../modules/nf-core/gawk' -include { MAJORITY_VOTE } from '../../../modules/local/majority_vote' +include { MIRNA_MAJORITYVOTE } from '../../../modules/local/mirna/majorityvote' include { MIRANDA } from '../../../modules/nf-core/miranda' -include { MIRNA_TARGETS } from '../../../modules/local/mirna_targets' +include { MIRNA_TARGETS } from '../../../modules/local/mirna/targets' include { PITA } from '../../../modules/local/pita' include { TARGETSCAN } from '../../../modules/local/targetscan/predict' include { TARPMIR } from '../../../modules/local/tarpmir' @@ -105,12 +105,12 @@ workflow MIRNA_BINDINGSITES { ch_combined_predictions = ch_predictions.map{meta, file -> file}.collect().map{[[id: "mirna"], it]}.collect() - MAJORITY_VOTE(ch_combined_predictions) - ch_versions = ch_versions.mix(MAJORITY_VOTE.out.versions) + MIRNA_MAJORITYVOTE(ch_combined_predictions) + ch_versions = ch_versions.mix(MIRNA_MAJORITYVOTE.out.versions) emit: - targets = MAJORITY_VOTE.out.targets - binding_sites = MAJORITY_VOTE.out.tsv + targets = MIRNA_MAJORITYVOTE.out.targets + binding_sites = MIRNA_MAJORITYVOTE.out.tsv versions = ch_versions } diff --git a/subworkflows/local/mirna_prediction.nf b/subworkflows/local/mirna_prediction.nf index 0be16b8c..d551668d 100644 --- a/subworkflows/local/mirna_prediction.nf +++ b/subworkflows/local/mirna_prediction.nf @@ -2,10 +2,10 @@ include { BIOAWK as ADD_BACKSPLICE } from '../../modules/nf-core/bioawk' include { MIRNA_NORMALIZATION } from '../../modules/local/deseq2/mirna_normalization' include { GENE_NORMALIZATION } from '../../modules/local/deseq2/gene_normalization' -include { MIRNA_FILTERING } from '../../modules/local/mirna_filtering' -include { COMPUTE_CORRELATIONS } from '../../modules/local/compute_correlations' -include { SPONGE } from '../../modules/local/sponge' -include { SPONGE_EFFECTS } from '../../modules/local/sponge_effects' +include { MIRNA_FILTERING } from '../../modules/local/mirna/filtering' +include { MIRNA_COMPUTECORRELATIONS } from '../../modules/local/mirna/computecorrelations' +include { SPONGE_SPONGE } from '../../modules/local/sponge/sponge' +include { SPONGE_SPONGEFFECTS } from '../../modules/local/sponge/spongeffects' // SUBWORKFLOWS include { MIRNA_BINDINGSITES } from './mirna/mirna_bindingsites' @@ -74,14 +74,14 @@ workflow MIRNA_PREDICTION { .splitText(by: 100, file: true) .map{ meta, file -> [[id: "batch_" + file.baseName.split("\\.").last()], file]} - COMPUTE_CORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) + MIRNA_COMPUTECORRELATIONS(ch_binding_site_batches, ch_mirna_filtered, quantification_rds) - ch_correlation_results = COMPUTE_CORRELATIONS.out.correlations + ch_correlation_results = MIRNA_COMPUTECORRELATIONS.out.correlations .map{meta, results -> results} .flatten().collect() .map{results -> [[id: 'correlation'], results]} - ch_versions = ch_versions.mix(COMPUTE_CORRELATIONS.out.versions) + ch_versions = ch_versions.mix(MIRNA_COMPUTECORRELATIONS.out.versions) // // SPONGE From c4b52a292727a5fafbe948c357bf78a4e954a4ce Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Sun, 19 Jan 2025 12:19:37 +0100 Subject: [PATCH 52/53] Add note on SPONGE execution --- nextflow_schema.json | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/nextflow_schema.json b/nextflow_schema.json index 7d52b02e..df731e04 100644 --- a/nextflow_schema.json +++ b/nextflow_schema.json @@ -138,7 +138,7 @@ "title": "miRNA options", "type": "object", "fa_icon": "fas fa-terminal", - "description": "Define paths and threasholds for miRNA analysis.", + "description": "Define thresholds for miRNA analysis. SPONGE is only run if the `mirna_expression` parameter is provided.", "properties": { "mirna_expression": { "type": "string", From 5a35f9909083e7d93778c342b0956b7949d74f1d Mon Sep 17 00:00:00 2001 From: Nico Trummer Date: Sun, 19 Jan 2025 12:40:11 +0100 Subject: [PATCH 53/53] Make ciriquant_de output optional --- modules/local/ciriquant/de/main.nf | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/modules/local/ciriquant/de/main.nf b/modules/local/ciriquant/de/main.nf index 0e3eb14a..3795151e 100644 --- a/modules/local/ciriquant/de/main.nf +++ b/modules/local/ciriquant/de/main.nf @@ -8,8 +8,8 @@ process CIRIQUANT_DE { tuple val(meta), path(library), path(expression), path(gene) output: - tuple val(meta), path("${circ_path}"), emit: circ - tuple val(meta), path("${gene_path}"), emit: gene + tuple val(meta), path("${circ_path}"), emit: circ, optional: true + tuple val(meta), path("${gene_path}"), emit: gene, optional: true path "versions.yml", emit: versions when:

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(A) : (B)) + +PRIVATE const paramT *P; + +PRIVATE int *indx; /* index for moving in the triangle matrices c[] and fMl[]*/ + +PRIVATE int *c; /* energy array, given that i-j pair */ +PRIVATE int *cc; /* linear array for calculating canonical structures */ +PRIVATE int *cc1; /* " " */ +PRIVATE int *f5; /* energy of 5' end */ +PRIVATE int *fML; /* multi-loop auxiliary energy array */ + +PRIVATE int *Fmi; /* holds row i of fML (avoids jumps in memory) */ +PRIVATE int *DMLi; /* DMLi[j] holds MIN(fML[i,k]+fML[k+1,j]) */ +PRIVATE int *DMLi1; /* MIN(fML[i+1,k]+fML[k+1,j]) */ +PRIVATE int *DMLi2; /* MIN(fML[i+2,k]+fML[k+1,j]) */ +PRIVATE int *pscore; /* precomputed array of pair types */ +PRIVATE int init_length=-1; + +/*--------------------------------------------------------------------------*/ + +PRIVATE void init_alifold(int length) +{ + unsigned int n; + if (length<1) nrerror("initialize_fold: argument must be greater 0"); + if (init_length>0) free_alifold_arrays(); + get_arrays((unsigned) length); + make_pair_matrix(); + init_length=length; + + for (n = 1; n <= (unsigned) length; n++) + indx[n] = (n*(n-1)) >> 1; /* n(n-1)/2 */ + + update_fold_params(); +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int size) +{ + indx = (int *) space(sizeof(int)*(size+1)); + c = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + fML = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + + pscore = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + f5 = (int *) space(sizeof(int)*(size+2)); + cc = (int *) space(sizeof(int)*(size+2)); + cc1 = (int *) space(sizeof(int)*(size+2)); + Fmi = (int *) space(sizeof(int)*(size+1)); + DMLi = (int *) space(sizeof(int)*(size+1)); + DMLi1 = (int *) space(sizeof(int)*(size+1)); + DMLi2 = (int *) space(sizeof(int)*(size+1)); + base_pair = (struct bond *) space(sizeof(struct bond)*(1+size/2)); +} + +/*--------------------------------------------------------------------------*/ + +void free_alifold_arrays(void) +{ + free(indx); free(c); free(fML); free(f5); free(cc); free(cc1); + free(pscore); + free(base_pair); free(Fmi); + free(DMLi); free(DMLi1);free(DMLi2); + init_length=0; +} + +/*--------------------------------------------------------------------------*/ +#define UNIT 100 +#define MINPSCORE -2 * UNIT +float alifold(char **strings, char *structure) +{ + struct sect { + int i; + int j; + int ml; + } + sector[MAXSECTORS]; /* backtracking sectors */ + + int i, j, k, p, q, length, energy, new_c; + int decomp, MLenergy, new_fML; + int s, b, mm, max_separation; + int n_seq, *type, type_2, tt; + short **S; + int cov_en = 0; + + length = (int) strlen(strings[0]); + if (length>init_length) init_alifold(length); + if ((P==NULL)||(fabs(P->temperature - temperature)>1e-6)) { + update_fold_params(); P = scale_parameters(); + } + for (s=0; strings[s]!=NULL; s++); + n_seq = s; + S = (short **) space(n_seq*sizeof(short *)); + type = (int *) space(n_seq*sizeof(int)); + for (s=0; sTURN?(j-TURN):1); i= 1; i--) { /* i,j in [1..length] */ + + for (j = i+TURN+1; j <= length; j++) { + int ij, psc; + ij = indx[j]+i; + + for (s=0; s=cv_fact*MINPSCORE) { /* a pair to consider */ + int stackEnergy = INF; + /* hairpin ----------------------------------------------*/ + + + for (new_c=s=0; sdangle3[tt][S[s][i+1]]; + d5 = P->dangle5[tt][S[s][j-1]]; + decomp += d5 + d3; + } + } + + MLenergy = decomp + n_seq*P->MLclosing; + for (s=0; sMLintern[type[s]]; + + new_c = MLenergy < new_c ? MLenergy : new_c; + + new_c = MIN2(new_c, cc1[j-1]+stackEnergy); + cc[j] = new_c - psc; /* add covariance bonnus/penalty */ + if (noLonelyPairs) + c[ij] = cc1[j-1]+stackEnergy-psc; + else + c[ij] = cc[j]; + + } /* end >> if (pair) << */ + + else c[ij] = INF; + + + /* done with c[i,j], now compute fML[i,j] */ + /* free ends ? -----------------------------------------*/ + + new_fML = fML[ij+1]+n_seq*P->MLbase; + new_fML = MIN2(fML[indx[j-1]+i]+n_seq*P->MLbase, new_fML); + energy = c[ij]; + for (s=0; sMLintern[type[s]]; + if (dangles) { /* double dangles */ + if (i>1) energy += P->dangle5[type[s]][S[s][i-1]]; + if (jdangle3[type[s]][S[s][j+1]]; + } + } + new_fML = MIN2(energy, new_fML); + + + /* modular decomposition -------------------------------*/ + + for (decomp = INF, k = i+1+TURN; k <= j-2-TURN; k++) + decomp = MIN2(decomp, Fmi[k]+fML[indx[j]+k+1]); + + DMLi[j] = decomp; /* store for use in ML decompositon */ + new_fML = MIN2(new_fML,decomp); + + /* coaxial stacking deleted */ + + fML[ij] = Fmi[j] = new_fML; /* substring energy */ + + } + + { + int *FF; /* rotate the auxilliary arrays */ + FF = DMLi2; DMLi2 = DMLi1; DMLi1 = DMLi; DMLi = FF; + FF = cc1; cc1=cc; cc=FF; + for (j=1; j<=length; j++) {cc[j]=Fmi[j]=DMLi[j]=INF; } + } + } + /* calculate energies of 5' and 3' fragments */ + + f5[TURN+1]=0; + for (j=TURN+2; j<=length; j++) { + f5[j] = f5[j-1]; + if (c[indx[j]+1]2) energy += TerminalAU; + if ((dangles)&&(jdangle3[type][S[s][j+1]]; + } + f5[j] = MIN2(f5[j], energy); + } + for (i=j-TURN-1; i>1; i--) { + if (c[indx[j]+i]2) energy += TerminalAU; + if (dangles) { + energy += P->dangle5[type][S[s][i-1]]; + if (jdangle3[type][S[s][j+1]]; + } + } + f5[j] = MIN2(f5[j], energy); + } + } + } + + + /*------------------------------------------------------------------ + trace back through the "c", "f5" and "fML" arrays to get the + base pairing list. No search for equivalent structures is done. + This inverts the folding procedure, hence it's very fast. + ------------------------------------------------------------------*/ + + b = s = 0; + sector[++s].i = 1; + sector[s].j = length; + sector[s].ml = (backtrack_type=='M') ? 1 : ((backtrack_type=='C')?2:0); + + while (s>0) { + int ss, ml, fij, fi, cij, traced, i1, j1, d3, d5, jj=0; + int canonical = 1; /* (i,j) closes a canonical structure */ + i = sector[s].i; + j = sector[s].j; + ml = sector[s--].ml; /* ml is a flag indicating if backtracking is to + occur in the fML- (1) or in the f-array (0) */ + if (ml==2) { + base_pair[++b].i = i; + base_pair[b].j = j; + cov_en += pscore[indx[j]+i]; + goto repeat1; + } + + if (j < i+TURN+1) continue; /* no more pairs in this interval */ + + fij = (ml)? fML[indx[j]+i] : f5[j]; + fi = (ml)?(fML[indx[j-1]+i]+n_seq*P->MLbase):f5[j-1]; + + if (fij == fi) { /* 3' end is unpaired */ + sector[++s].i = i; + sector[s].j = j-1; + sector[s].ml = ml; + continue; + } + + if (ml == 0) { /* backtrack in f5 */ + /* j or j-1 is paired. Find pairing partner */ + for (i=j-TURN-1,traced=0; i>=1; i--) { + int cc, en; + jj = i-1; + if (c[indx[j]+i]2) cc += TerminalAU; + } + en = cc + f5[i-1]; + if (dangles) { + for (ss=0; ss1) en += P->dangle5[type[ss]][S[ss][i-1]]; + if (jdangle3[type[ss]][S[ss][j+1]]; + } + } + if (fij == en) traced=j; + } + if (traced) break; + } + + if (!traced) nrerror("backtrack failed in f5"); + sector[++s].i = 1; + sector[s].j = jj; + sector[s].ml = ml; + + j=traced; + base_pair[++b].i = i; + base_pair[b].j = j; + cov_en += pscore[indx[j]+i]; + goto repeat1; + } + else { /* trace back in fML array */ + int cij1=INF, ci1j=INF, ci1j1=INF; + if (fML[indx[j]+i+1]+n_seq*P->MLbase == fij) { /* 5' end is unpaired */ + sector[++s].i = i+1; + sector[s].j = j; + sector[s].ml = ml; + continue; + } + + cij = c[indx[j]+i]; + for (ss=0; ssMLintern[tt]; + if (dangles) { /* double dangles */ + if (i>1) cij += P->dangle5[tt][S[ss][i-1]]; + if (jdangle3[tt][S[ss][j+1]]; + } + } + + if ((fij==cij)||(fij==ci1j)||(fij==cij1)||(fij==ci1j1)) { + /* found a pair */ + if (fij==ci1j) i++; + else if (fij==cij1) j--; + else if (fij==ci1j1) {i++; j--;} + base_pair[++b].i = i; + base_pair[b].j = j; + cov_en += pscore[indx[j]+i]; + goto repeat1; + } + + for (k = i+1+TURN; k <= j-2-TURN; k++) + if (fij == (fML[indx[k]+i]+fML[indx[j]+k+1])) + break; + + sector[++s].i = i; + sector[s].j = k; + sector[s].ml = ml; + sector[++s].i = k+1; + sector[s].j = j; + sector[s].ml = ml; + + if (k>j-2-TURN) nrerror("backtrack failed in fML"); + continue; + } + + repeat1: + + /*----- begin of "repeat:" -----*/ + if (canonical) cij = c[indx[j]+i]; + + for (ss=0; ssstack[type[ss]][type_2]; + } + cij += pscore[indx[j]+i]; + base_pair[++b].i = i+1; + base_pair[b].j = j-1; + cov_en += pscore[indx[j-1]+i+1]; + i++; j--; + canonical=0; + goto repeat1; + } + canonical = 1; + cij += pscore[indx[j]+i]; + + {int cc=0; + for (ss=0; ss= minq; q--) { + + if (c[indx[q]+p]>=INF) continue; + + for (ss=energy=0; ssMLclosing; + for (ss=d3=d5=0; ssMLintern[tt]; + d5 += P->dangle5[tt][S[ss][j-1]]; + d3 += P->dangle3[tt][S[ss][i+1]]; + } + i1 = i+1; j1 = j-1; + sector[s+1].ml = sector[s+2].ml = 1; + + for (k = i+2+TURN; k < j-2-TURN; k++) { + int en; + en = fML[indx[k]+i+1]+fML[indx[j-1]+k+1]+mm; + if (dangles) /* double dangles */ + en += d5+d3; + if (cij == en) + break; + + } + if (k<=j-3-TURN) { /* found the decomposition */ + sector[++s].i = i1; + sector[s].j = k; + sector[++s].i = k+1; + sector[s].j = j1; + } else { + nrerror("backtracking failed in repeat"); + } + + } + + base_pair[0].i = b; /* save the total number of base pairs */ + + parenthesis_structure(structure, length); + + free(type); + for (s=0; s0 for good pairs */ +#define NONE -10000 /* score for forbidden pairs */ + int n,i,j,k,l,s,score; + int dm[7][7]={{0,0,0,0,0,0,0}, /* hamming distance between pairs */ + {0,0,2,2,1,2,2} /* CG */, + {0,2,0,1,2,2,2} /* GC */, + {0,2,1,0,2,1,2} /* GU */, + {0,1,2,2,0,2,1} /* UG */, + {0,2,2,1,2,0,2} /* AU */, + {0,2,2,2,1,2,0} /* UA */}; + n=S[0][0]; /* length of seqs */ + for (i=1; in_seq) { pscore[indx[j]+i] = NONE; continue;} + for (k=1,score=0; k<=6; k++) /* ignore pairtype 7 (gap-gap) */ + for (l=k+1; l<=6; l++) + /* scores for replacements between pairtypes */ + /* consistent or compensatory mutations score 1 or 2 */ + score += pfreq[k]*pfreq[l]*dm[k][l]; + /* counter examples score -1, gap-gap scores -0.25 */ + pscore[indx[j]+i] = cv_fact * + ((UNIT*score)/n_seq - nc_fact*UNIT*(pfreq[0] + pfreq[7]*0.25)); + } + } + + if (noLonelyPairs) /* remove unwanted pairs */ + for (k=1; k=1)&&(j<=n)) { + if ((i>1)&&(j0) ? psij : 0; + /* fallthrough */ + case '>': /* pairs downstream */ + for (l=j+TURN+1; l<=n; l++) pscore[indx[l]+j] = NONE; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in constraint string"); + } + free(stack); + } +} diff --git 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zIUi^^%1KT}Zp-?daPHUq!_j{=aQ;=EuQfT?E*yV&BbDv&HOX&78>}q@Wl8`SUmf=XF`Ffmf0K4;lDJr2pdv&hd6vEBLDhzL5Ot zT?6OmKL2Ro^Qb?bH*go>DYPzOJ5)%sSvMFs*LRMAbNf~qcnQf58MvG5^HT%AoXY)$ zf%87hlLp?Eo7Qb?w`6LUjs|{=+P$ZN zXOVx7Gw{x&=TyQ`J?i?xLRkj?_ar}0<40(L;I^z=4gLn=zeD4vB1H~fk8-_u-;JM7 zLw%5cqTsfy=MDM%9QHmcg?4E}Cp|KkQfe-HPJ!G9(3^ZV=APx$+}ZD>D( z^|_q-ODDpazlQX=!r=cswON0SAB&tw_;xy@9BL|o(6Up^qvD7MPfVNq */ +/* + partiton function and base pair probabilities + for RNA secvondary structures + of a set of aligned sequences + + Ivo L Hofacker + Vienna RNA package +*/ + +#include +#include +#include +#include +#include /* #defines FLT_MIN */ +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "alifold.h" +/*@unused@*/ +static char rcsid[] = "$Id: alipfold.c,v 1.10 2005/09/09 08:03:16 ivo Exp $"; + +#define MAX(x,y) (((x)>(y)) ? (x) : (y)) +#define MIN(x,y) (((x)<(y)) ? (x) : (y)) +#define PUBLIC +#define PRIVATE static +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define NEW_NINIO 1 /* new asymetry penalty */ + + + +PUBLIC float alipf_fold(char **sequences, char *structure, pair_info **pi); +PRIVATE void init_alipf_fold(int length, int n_seq); +PRIVATE void free_alipf_arrays(void); +/* PRIVATE void update_alipf_params(int length); */ +PRIVATE void sprintf_bppm(int length, char *structure); +PRIVATE void scale_pf_params(unsigned int length, int n_seq); +PRIVATE void get_arrays(unsigned int length); +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1); +PRIVATE void make_pscores(const short *const *S, const char *const* AS, + int n_seq, const char *structure); +PRIVATE pair_info *make_pairinfo(const short *const* S, char **AS, + int n_seq); +PRIVATE short * encode_seq(const char *sequence); +PRIVATE FLT_OR_DBL expMLclosing, expMLintern[NBPAIRS+1], *expMLbase; +PRIVATE FLT_OR_DBL expTermAU; +PRIVATE FLT_OR_DBL expdangle5[NBPAIRS+1][5], expdangle3[NBPAIRS+1][5]; +PRIVATE FLT_OR_DBL lxc, exptetra[40], expTriloop[40]; +PRIVATE FLT_OR_DBL expstack[NBPAIRS+1][NBPAIRS+1]; +PRIVATE FLT_OR_DBL expmismatchI[NBPAIRS+1][5][5], + expmismatchH[NBPAIRS+1][5][5], expmismatchM[NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint11[NBPAIRS+1][NBPAIRS+1][5][5]; +PRIVATE FLT_OR_DBL expint21[NBPAIRS+1][NBPAIRS+1][5][5][5]; +PRIVATE FLT_OR_DBL expint22[NBPAIRS+1][NBPAIRS+1][5][5][5][5]; +PRIVATE FLT_OR_DBL *exphairpin; +PRIVATE FLT_OR_DBL expbulge[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expinternal[MAXLOOP+1]; +PRIVATE FLT_OR_DBL expninio[5][MAXLOOP+1]; +PRIVATE FLT_OR_DBL *q, *qb, *qm, *qqm, *qqm1, *qq, *qq1; +PRIVATE FLT_OR_DBL *prml, *prm_l, *prm_l1, *q1k, *qln; +PRIVATE FLT_OR_DBL *scale; +PRIVATE short *pscore; /* precomputed array of covariance bonus/malus */ +PRIVATE int init_length; /* length in last call to init_pf_fold() */ +#define ISOLATED 256.0 + +#define UNIT 100 +#define MINPSCORE -2 * UNIT + +extern double cv_fact /* =1 */; +extern double nc_fact /* =1 */; + +/*-----------------------------------------------------------------*/ +PUBLIC float alipf_fold(char **sequences, char *structure, pair_info **pi) +{ + short **S; + int s, *type; + int n, n_seq, i,j,k,l, ij, kl, u,u1,d,ii,ll, type_2, tt, ov=0; + FLT_OR_DBL temp, Q, Qmax=0, prm_MLb; + FLT_OR_DBL prmt,prmt1; + FLT_OR_DBL qbt1, *tmp; + + double free_energy, kTn; + + n = (int) strlen(sequences[0]); + for (s=0; sequences[s]!=NULL; s++); + n_seq = s; + init_alipf_fold(n, n_seq); /* (re)allocate space */ + kTn = (temperature+K0)*GASCONST*n_seq/10.; /* kT in cal/mol */ + + S = (short **) space(sizeof(short *)*(n_seq+1)); + type = (int *) space(n_seq*sizeof(int)); + for (s=0; s=1; i--) { + int ij, psc; + /* construction of partition function for segment i,j */ + /* calculate pf given that i and j pair: qb(i,j) */ + u = j-i-1; ij = iindx[i]-j; + + for (s=0; s=cv_fact*MINPSCORE) { /* otherwise ignore this pair */ + + /* hairpin contribution */ + for (qbt1=1,s=0; s2) + qbt1 *= expTermAU; + } + else /* no mismatches for tri-loops */ + qbt1 *= expmismatchH[type[s]][S[s][i+1]][S[s][j-1]]; + } + qbt1 *= scale[u+2]; + + /* interior loops with interior pair k,l */ + for (k=i+1; k<=MIN(i+MAXLOOP+1,j-TURN-2); k++) { + u1 = k-i-1; + for (l=MAX(k+TURN+1,j-1-MAXLOOP+u1); l<=j-1; l++) { + double qloop=1; + if (qb[iindx[k]-l]==0) {qloop=0; continue;} + for (s=0; s1) qbt1 *= expdangle5[type[s]][S[s][i-1]]; + if (j2) qbt1 *= expTermAU; + } + qqm[i] += qb[ij]*qbt1; + /* construction of qm matrix containing multiple loop + partition function contributions from segment i,j */ + temp = 0.0; + ii = iindx[i]; /* ii-k=[i,k-1] */ + for (k=i+1; k<=j; k++) + temp += (qm[ii-(k-1)]+expMLbase[k-i])*qqm[k]; + qm[ij] = (temp + qqm[i]); + + /* auxiliary matrix qq for cubic order q calculation below */ + qbt1 = qb[ij]; + if (qbt1>0) + for (s=0; s1) qbt1 *= expdangle5[type[s]][S[s][i-1]]; + if (j2) qbt1 *= expTermAU; + } + qq[i] = qq1[i]*scale[1] + qbt1; + + /* construction of partition function for segment i,j */ + temp = 1.0*scale[1+j-i] + qq[i]; + for (k=i; k<=j-1; k++) temp += q[ii-k]*qq[k+1]; + q[ij] = temp; + +#ifndef LARGE_PF + if (temp>Qmax) { + Qmax = temp; + if (Qmax>FLT_MAX/10.) + fprintf(stderr, "%d %d %g\n", i,j,temp); + } + if (temp>FLT_MAX) { + PRIVATE char msg[128]; + sprintf(msg, "overflow in pf_fold while calculating q[%d,%d]\n" + "use larger pf_scale", i,j); + nrerror(msg); + } +#endif + } + tmp = qq1; qq1 =qq; qq =tmp; + tmp = qqm1; qqm1=qqm; qqm=tmp; + } + if (backtrack_type=='C') Q = qb[iindx[1]-n]; + else if (backtrack_type=='M') Q = qm[iindx[1]-n]; + else Q = q[iindx[1]-n]; + + /* ensemble free energy in Kcal/mol */ + if (Q<=FLT_MIN) fprintf(stderr, "pf_scale too large\n"); + free_energy = (-log(Q)-n*log(pf_scale))*(temperature+K0)*GASCONST/1000.0; + /* in case we abort because of floating point errors */ + if (n>1600) fprintf(stderr, "free energy = %8.2f\n", free_energy); + + /* backtracking to construct binding probabilities of pairs*/ + + if (do_backtrack) { + Qmax=0; + + for (k=1; k<=n; k++) { + q1k[k] = q[iindx[1] - k]; + qln[k] = q[iindx[k] -n]; + } + q1k[0] = 1.0; + qln[n+1] = 1.0; + + pr = q; /* recycling */ + + /* 1. exterior pair i,j and initialization of pr array */ + for (i=1; i<=n; i++) { + for (j=i; j<=MIN(i+TURN,n); j++) pr[iindx[i]-j] = 0; + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + if (qb[ij]>0.) { + pr[ij] = q1k[i-1]*qln[j+1]/q1k[n] * exp(pscore[ij]/kTn); + for (s=0; s1) pr[ij] *= expdangle5[typ][S[s][i-1]]; + if (j2) pr[ij] *= expTermAU; + } + } else + pr[ij] = 0; + } + } + + for (l=n; l>TURN+1; l--) { + + /* 2. bonding k,l as substem of 2:loop enclosed by i,j */ + for (k=1; k0)) { + double qloop=1; + for (s=0; s1) temp *= expdangle5[tt][S[s][k-1]]; + if (l2) temp *= expTermAU; + } + pr[kl] += temp * scale[2] * exp(pscore[kl]/kTn); + +#ifndef LARGE_PF + if (pr[kl]>Qmax) { + Qmax = pr[kl]; + if (Qmax>FLT_MAX/10.) + fprintf(stderr, "%d %d %g %g\n", i,j,pr[kl],qb[kl]); + } + if (pr[kl]>FLT_MAX) { + ov++; + pr[kl]=FLT_MAX; + } +#endif + } /* end for (k=..) */ + tmp = prm_l1; prm_l1=prm_l; prm_l=tmp; + + } /* end for (l=..) */ + + for (i=1; i<=n; i++) + for (j=i+TURN+1; j<=n; j++) { + ij = iindx[i]-j; + pr[ij] *= qb[ij] *exp(-pscore[ij]/kTn); + } + + if (pi != NULL) + *pi = make_pairinfo((const short **)S, sequences, n_seq); + + if (structure!=NULL) + sprintf_bppm(n, structure); + } /* end if (do_backtrack)*/ + + for (i=0; i0) fprintf(stderr, "%d overflows occurred while backtracking;\n" + "you might try a smaller pf_scale than %g\n", + ov, pf_scale); + free(type); + free_alipf_arrays(); + return (free_energy); +} + +/*------------------------------------------------------------------------*/ +/* dangling ends should never be destabilizing, i.e. expdangle>=1 */ +/* specific heat needs smooth function (2nd derivative) */ +/* we use a*(sin(x+b)+1)^2, with a=2/(3*sqrt(3)), b=Pi/6-sqrt(3)/2, */ +/* in the interval b0.8660254)?(X):\ + SCALE*0.38490018*(sin((X)/SCALE-0.34242663)+1)*(sin((X)/SCALE-0.34242663)+1)) + +PRIVATE void scale_pf_params(unsigned int length, int n_seq) +{ + /* scale energy parameters and pre-calculate Boltzmann weights */ + unsigned int i, j, k, l; + double kT, TT, kTn; + double GT; + + + + kT = (temperature+K0)*GASCONST; /* kT in cal/mol */ + kTn = kT*n_seq; + TT = (temperature+K0)/(Tmeasure); + + /* scaling factors (to avoid overflows) */ + if (pf_scale==-1) { /* mean energy for random sequences: 184.3*length cal */ + pf_scale = exp(-(-185+(temperature-37.)*7.27)/kT); + if (pf_scale<1) pf_scale=1; + } + scale[0] = 1.; + for (i=1; i<=length; i++) { + scale[i] = scale[i-1]/pf_scale; + } + + /* loop energies: hairpins, bulges, interior, mulit-loops */ + for (i=0; i<=MIN(30,length); i++) { + GT = hairpin37[i]*TT; + exphairpin[i] = exp( -GT*10./kTn); + } + for (i=0; i<=MIN(30, MAXLOOP); i++) { + GT = bulge37[i]*TT; + expbulge[i] = exp( -GT*10./kTn); + GT = internal_loop37[i]*TT; + expinternal[i] = exp( -GT*10./kTn); + } + /* special case of size 2 interior loops (single mismatch) */ + if (james_rule) expinternal[2] = exp ( -80*10/kTn); + + lxc = lxc37*TT; + for (i=31; i2) GT += TerminalAU; */ + expMLintern[i] = exp( -GT*10./kTn); + } + expTermAU = exp(-TerminalAU*10/kTn); + + GT = ML_BASE37*TT; + for (i=0; i 0 (at large temps), + but make sure go smoothly to 0 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=4; j++) { + GT = dangle5_H[i][j] - (dangle5_H[i][j] - dangle5_37[i][j])*TT; + expdangle5[i][j] = dangles?exp(SMOOTH(-GT)*10./kTn):1.; + GT = dangle3_H[i][j] - (dangle3_H[i][j] - dangle3_37[i][j])*TT; + expdangle3[i][j] = dangles?exp(SMOOTH(-GT)*10./kTn):1.; + if (i>2) /* add TermAU penalty into dangle3 */ + expdangle3[i][j] *= expTermAU; + } + + /* stacking energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) { + GT = enthalpies[i][j] - (enthalpies[i][j] - stack37[i][j])*TT; + expstack[i][j] = exp( -GT*10/kTn); + } + + /* mismatch energies */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<5; j++) + for (k=0; k<5; k++) { + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchI37[i][j][k])*TT; + expmismatchI[i][j][k] = exp(-GT*10.0/kTn); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchH37[i][j][k])*TT; + expmismatchH[i][j][k] = exp(-GT*10.0/kTn); + GT = mism_H[i][j][k] - (mism_H[i][j][k] - mismatchM37[i][j][k])*TT; + expmismatchM[i][j][k] = exp(-GT*10.0/kTn); + } + + /* interior lops of length 2 */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + GT = int11_H[i][j][k][l] - + (int11_H[i][j][k][l] - int11_37[i][j][k][l])*TT; + expint11[i][j][k][l] = exp(-GT*10./kTn); + } + /* interior 2x1 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m; + for (m=0; m<5; m++) { + GT = int21_H[i][j][k][l][m] - + (int21_H[i][j][k][l][m] - int21_37[i][j][k][l][m])*TT; + expint21[i][j][k][l][m] = exp(-GT*10./kTn); + } + } + /* interior 2x2 loops */ + for (i=0; i<=NBPAIRS; i++) + for (j=0; j<=NBPAIRS; j++) + for (k=0; k<5; k++) + for (l=0; l<5; l++) { + int m,n; + for (m=0; m<5; m++) + for (n=0; n<5; n++) { + GT = int22_H[i][j][k][l][m][n] - + (int22_H[i][j][k][l][m][n]-int22_37[i][j][k][l][m][n])*TT; + expint22[i][j][k][l][m][n] = exp(-GT*10./kTn); + } + } +} + +/*----------------------------------------------------------------------*/ + +PRIVATE double expLoopEnergy(int u1, int u2, int type, int type2, + short si1, short sj1, short sp1, short sq1) { + double z=0; + int no_close = 0; + + if ((no_closingGU) && ((type2==3)||(type2==4)||(type==2)||(type==4))) + no_close = 1; + + if ((u1==0) && (u2==0)) /* stack */ + z = expstack[type][type2]; + else if (no_close==0) { + if ((u1==0)||(u2==0)) { /* bulge */ + int u; + u = (u1==0)?u2:u1; + z = expbulge[u]; + if (u2+u1==1) z *= expstack[type][type2]; + else { + if (type>2) z *= expTermAU; + if (type2>2) z *= expTermAU; + } + } + else { /* interior loop */ + if (u1+u2==2) /* size 2 is special */ + z = expint11[type][type2][si1][sj1]; + else if ((u1==1) && (u2==2)) + z = expint21[type][type2][si1][sq1][sj1]; + else if ((u1==2) && (u2==1)) + z = expint21[type2][type][sq1][si1][sp1]; + else if ((u1==2) && (u2==2)) + z = expint22[type][type2][si1][sp1][sq1][sj1]; + else { + z = expinternal[u1+u2]* + expmismatchI[type][si1][sj1]* + expmismatchI[type2][sq1][sp1]; + z *= expninio[2][abs(u1-u2)]; + } + } + } + return z; +} + +/*----------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int length) +{ + unsigned int size,i; + + size = sizeof(FLT_OR_DBL) * ((length+1)*(length+2)/2); + q = (FLT_OR_DBL *) space(size); + qb = (FLT_OR_DBL *) space(size); + qm = (FLT_OR_DBL *) space(size); + pscore = (short *) space(sizeof(short)*((length+1)*(length+2)/2)); + q1k = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + qln = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qq1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + qqm1 = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prm_l1 =(FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + prml = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+2)); + exphairpin = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + expMLbase = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + scale = (FLT_OR_DBL *) space(sizeof(FLT_OR_DBL)*(length+1)); + iindx = (int *) space(sizeof(int)*(length+1)); + for (i=1; i<=length; i++) { + iindx[i] = ((length+1-i)*(length-i))/2 +length+1; + } +} + +/*----------------------------------------------------------------------*/ + +PUBLIC void init_alipf_fold(int length, int n_seq) +{ + if (length<1) nrerror("init_pf_fold: length must be greater 0"); + if (init_length>0) free_alipf_arrays(); /* free previous allocation */ +#ifdef SUN4 + nonstandard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(1); +#endif +#endif + make_pair_matrix(); + get_arrays((unsigned) length); + scale_pf_params((unsigned) length, n_seq); + init_length=length; +} + +PRIVATE void free_alipf_arrays(void) +{ + free(q); + free(qb); + free(qm); + free(pscore); + free(qq); free(qq1); + free(qqm); free(qqm1); + free(q1k); free(qln); + free(prm_l); free(prm_l1); free(prml); + free(exphairpin); + free(expMLbase); + free(scale); + free(iindx); +#ifdef SUN4 + standard_arithmetic(); +#else +#ifdef HP9 + fpsetfastmode(0); +#endif +#endif + init_length=0; +} +/*---------------------------------------------------------------------------*/ +#define PMIN 0.0008 +PRIVATE int compare_pair_info(const void *pi1, const void *pi2) { + pair_info *p1, *p2; + int i, nc1, nc2; + p1 = (pair_info *)pi1; p2 = (pair_info *)pi2; + for (nc1=nc2=0, i=1; i<=6; i++) { + if (p1->bp[i]>0) nc1++; + if (p2->bp[i]>0) nc2++; + } + /* sort mostly by probability, add + epsilon * comp_mutations/(non-compatible+1) to break ties */ + return (p1->p + 0.01*nc1/(p1->bp[0]+1.)) < + (p2->p + 0.01*nc2/(p2->bp[0]+1.)) ? 1 : -1; +} + +pair_info *make_pairinfo(const short *const* S, char **AS, int n_seq) { + int i,j,n, num_p=0, max_p = 64; + pair_info *pi; + double *duck, p; + n = S[0][0]; + max_p = 64; pi = space(max_p*sizeof(pair_info)); + duck = (double *) space((n+1)*sizeof(double)); + for (i=1; i0) { + duck[i] -= p * log(p); + duck[j] -= p * log(p); + } + + for (i=1; i=PMIN) { + int type, s; + pi[num_p].i = i; + pi[num_p].j = j; + pi[num_p].p = p; + pi[num_p].ent = duck[i]+duck[j]-p*log(p); + for (type=0; type<8; type++) pi[num_p].bp[type]=0; + for (s=0; s=max_p) { + max_p *= 2; + pi = realloc(pi, max_p * sizeof(pair_info)); + if (pi==NULL) nrerror("out of memory in alipf_fold"); + } + } + } + free(duck); + pi = realloc(pi, (num_p+1)*sizeof(pair_info)); + pi[num_p].i=0; + qsort(pi, num_p, sizeof(pair_info), compare_pair_info ); + return pi; +} +/*---------------------------------------------------------------------------*/ + +#define L 3 +PRIVATE void sprintf_bppm(int length, char *structure) +{ + extern char bppm_symbol(float *x); + int i,j; + float P[L]; /* P[][0] unpaired, P[][1] upstream p, P[][2] downstream p */ + + for( j=1; j<=length; j++ ) { + P[0] = 1.0; + P[1] = P[2] = 0.0; + for( i=1; i0 for good pairs */ +#define NONE -10000 /* score for forbidden pairs */ + int n,i,j,k,l,s,score; + int dm[7][7]={{0,0,0,0,0,0,0}, /* hamming distance between pairs */ + {0,0,2,2,1,2,2} /* CG */, + {0,2,0,1,2,2,2} /* GC */, + {0,2,1,0,2,1,2} /* GU */, + {0,1,2,2,0,2,1} /* UG */, + {0,2,2,1,2,0,2} /* AU */, + {0,2,2,2,1,2,0} /* UA */}; + + n=S[0][0]; /* length of seqs */ + for (i=1; in_seq) { pscore[iindx[i]-j] = NONE; continue;} + for (k=1,score=0; k<=6; k++) /* ignore pairtype 7 (gap-gap) */ + for (l=k+1; l<=6; l++) + /* scores for replacements between pairtypes */ + /* consistent mutations (if l==k+2) score 1 */ + /* compensatory (all else) score 2 */ + score += pfreq[k]*pfreq[l]*dm[k][l]; + /* counter examples score -1, gap-gap scores -0.25 */ + pscore[iindx[i]-j] = cv_fact * + ((UNIT*score)/n_seq - nc_fact*UNIT*(pfreq[0] + pfreq[7]*0.25)); + } + } + + if (noLonelyPairs) /* remove unwanted pairs */ + for (k=1; k<=n-TURN-1; k++) + for (l=1; l<=2; l++) { + int type,ntype=0,otype=0; + i=k; j = i+TURN+l; + type = pscore[iindx[i]-j]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j0) ? psij : 0; + /* fallthrough */ + case '>': /* j pairs downstream */ + for (l=j+TURN+1; l<=n; l++) pscore[iindx[j]-l] = NONE; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in constraint string"); + } + free(stack); + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/alipfold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/alipfold.o new file mode 100755 index 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F{{U5JkBtBT literal 0 HcmV?d00001 diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/aln_util.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/aln_util.c new file mode 100755 index 00000000..2ef82832 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/aln_util.c @@ -0,0 +1,151 @@ +/* + aln_util.c + Helper functions frelated to alignments +*/ +/* Last changed Time-stamp: <2006-01-16 11:42:38 ivo> */ + +#include +#include +#include +#include +#include +#include +#include +#include "utils.h" +#include "fold_vars.h" +#include "pair_mat.h" +/*@unused@*/ +static char rcsid[] = "$Id: aln_util.c,v 1.2 2006/01/18 13:00:30 ivo Exp $"; + +#define MAX_NUM_NAMES 500 +int read_clustal(FILE *clust, char *AlignedSeqs[], char *names[]) { + char *line, name[100]="", *seq; + int n, nn=0, num_seq = 0; + + if ((line=get_line(clust)) == NULL) { + fprintf(stderr, "Empty CLUSTAL file\n"); return 0; + } + + if (strncmp(line,"CLUSTAL", 7) !=0) { + fprintf(stderr, "This doesn't look like a CLUSTAL file, sorry\n"); + free(line); return 0; + } + free(line); + line = get_line(clust); + + while (line!=NULL) { + if (((n=strlen(line))<4) || isspace((int)line[0])) { + /* skip non-sequence line */ + free(line); line = get_line(clust); + nn=0; /* reset seqence number */ + continue; + } + + seq = (char *) space( (n+1)*sizeof(char) ); + sscanf(line,"%99s %s", name, seq); + if (nn == num_seq) { /* first time */ + names[nn] = strdup(name); + AlignedSeqs[nn] = strdup(seq); + } + else { + if (strcmp(name, names[nn])!=0) { + /* name doesn't match */ + fprintf(stderr, + "Sorry, your file is fucked up (inconsitent seq-names)\n"); + free(line); free(seq); + return 0; + } + AlignedSeqs[nn] = (char *) + xrealloc(AlignedSeqs[nn], strlen(seq)+strlen(AlignedSeqs[nn])+1); + strcat(AlignedSeqs[nn], seq); + } + nn++; + if (nn>num_seq) num_seq = nn; + free(seq); + free(line); + if (num_seq>=MAX_NUM_NAMES) { + fprintf(stderr, "Too many sequences in CLUSTAL file"); + return 0; + } + + line = get_line(clust); + } + + AlignedSeqs[num_seq] = NULL; + if (num_seq == 0) { + fprintf(stderr, "No sequences found in CLSUATL file\n"); + return 0; + } + n = strlen(AlignedSeqs[0]); + for (nn=1; nnfm) {c=s, fm=freq[c];} + if (s>4) s++; /* skip T */ + string[i]=Law_and_Order[c]; + } + return string; +} + +/* IUP nucleotide classes indexed by a bit string of the present bases */ +/* A C AC G AG CG ACG U AU CU ACU GU AGU CGU ACGU */ +static char IUP[17] = "-ACMGRSVUWYHKDBN"; +char *consens_mis(const char*AS[]) { + /* MIS displays the 'most informative sequence' (Freyhult et al 2004), + elements in columns with frequency greater than the background + frequency are projected into iupac notation. Columns where gaps are + over-represented are in lower case. */ + + char *cons; + int i, s, n, N, c; + int bgfreq[8] = {0,0,0,0,0,0,0,0}; + + n = strlen(AS[0]); + for (N=0; AS[N]!=NULL; N++); + cons = (char *) space((n+1)*sizeof(char)); + + for (i=0; i4) c=5; + bgfreq[c]++; + } + + for (i=0; i4) c=5; + freq[c]++; + } + for (c=4; c>0; c--) { + code <<=1; + if (freq[c]*n>=bgfreq[c]) code++; + } + cons[i] = IUP[code]; + if (freq[0]*n>=bgfreq[0]) + cons[i] = tolower(IUP[code]); + } + return cons; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/aln_util.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/aln_util.o new file mode 100755 index 0000000000000000000000000000000000000000..9d367064c2a27bfde9ec16ed4685972872db45cd GIT binary patch literal 17584 zcmcIr3wYdBmB0V_C+)ONGilP7w8%hHNFkYI+Cr1ig``c}NeLz9Q7U~*CX>m-CNt?g z`hd~~(<)<{wkRq}@k7}a&_zMrT9B=wPmp!3Y|$dRU|rWL6hsvH05^Niz32Sr<|ff^ z{l2|l^S|f(?s?sF@BiMpcc!~n)U9+`mf&KE8$^aYPY>1)rOyQVPq>e_x3?bz#7<_q}nzYy3v6i7dl{Ka54^64KeIOZSf ze=pnfz!0h|IF>#m)j(7ItG=~1JzTxEy1BZkxiN6p>-T|{=de@`4DKwvJdjQn&JLuT z3iJH$JQaqwniyAKx`wwR?^>i@<<*r>5TWdiG%cSPX(-6C4bf zN#WQ{n8r&jn6r9m5DcdmcvZfg0%4K)F;!Jsc4bbf=G3G!^FDxi}EM zfWcrqU?@i#2@EVfrhHXg@a+9}P#K0Mu;i|Qdgo6-9|Zpay`*0{ij{vz%A-i&t`nHq z^&6`DoEEqq-hV{VJVrxra~_acy0O=x#Y}n zV4giMg2B3Q8%9@Cn1`e4T|Kb)RjI#s$g_7Ic&tnRS=qyM)uvCb9+-PRkbXsC)q^$J zknmRqd&y_|v`k=K`kmG3rOJ*>1tbvcU;Sax^KKM3%- z^B}AWMRn`ykcP3uV9OvjoDcA-sTT_07B_S(&|fKD%TwI& z$=dMAK>yNXBK1b~;4W*0U%j_0DsZ?8J%b*Y73kT2v8LkUo!15iU_fsU|K?y|z+MKu z^MR;+1O-h_O3&d)8F zV&~4u6~Z-B*twNcuAfp1uYz3&%#LQI^hRI_Uf z$|noqMlm5KT`ADiWVS2B6p{lQD3@b_6%?6zIY^d*O0G}ZMXOik)D}#$@~x@~Fs#`S zf(p$AY~ErgQe>x1v6`XE2UHU(KvOs7s4nTorh_r+Cu+~oj6qB@r$AEjVb;yc;6lvK zFgNBbh0X0l8DK8t?h;_xHy9D;z%cA{P~2c@?BX;?!3i&xgP4t??uoLp+_G{hE{nhk z3e3*xiY7%?wo=HJCbAE7fwm$KBB>fDX1j4lNyeHWn{D4e0WzUlG7zop!>w3ksD+&v3ZIuAa=H5rxWW{>vp&2$Yw@6MPA*@Se)KbxSc*4+%cCqB)!~xfM%|KBs#0uOAN3+tcYbLvpACX-%CxEbh z&zW8MiO3dM=(sgMDqOQT!u+VtDLYQ%Oyw-|oQ0%oQ3*UX5_9=QfU@1_B4;MJb@Ch* z1&;%-db>eRVvreCJk^cDwP6j61r`;?CMV!7;RDKfW!NrI-Ucb5LU@PC`Wzo0y|9 z*45Zy%gV7}#m5&`CUBCF;aOQT0i8ti7O1x%t2uta(1J=eC0x!SD|-&K<;2rx@Ra9R%jYW%h|*LdUfLB6cc?Xm8*;MPzao8-Kn1Zt|-AF@{4lm24g{^;4J z%Hl&GukmHM?AV*`%EO2Lu;eXwf%~I<_WVcfO@pqhrn!sl%XY6@yK?Q-eI2I`7ysV< z$jk1&fL-I>?LK7BuCV7d+qZA=+YOKQ?W#O~&V9kPc-oTMTLXde^K1Lg+8#GF-|t>; 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+ int *fM_d3, *fM_d5, Md3i, Md5i, FcMd3, FcMd5; + int i,j, p,q,length, energy, bonus=0, bonus_cnt=0; + int s=0; + /* if (!uniq_ML) {uniq_ML=1; init_length=-1;} */ + length = (int) strlen(string); + if (length>init_length) initialize_fold(length); + if (fabs(P->temperature - temperature)>1e-6) update_fold_params(); + + encode_seq(string); + + BP = (int *)space(sizeof(int)*(length+2)); + make_ptypes(S, structure); + + /* compute all arrays used by fold() for linear RNA */ + energy = fill_arrays(string); + + /* extra arrays for circfold() */ + fM2 = (int *) space(sizeof(int)*(length+2)); + FcH = FcI= FcM = FcMd3= FcMd5= Fc = INF; + for (i=1; i max_separation) type = 0; */ /* forces locality degree */ + + type=rtype[type]; + if (!type) continue; + if (no_close) new_c = FORBIDDEN; + else { + char loopseq[10]; + int si1, sj1; + if (u<7) { + strcpy(loopseq , string+j-1); + strncat(loopseq, string, i); + } + si1 = (i==1)?S1[length] : S1[i-1]; + sj1 = (j==length)?S1[1] : S1[j+1]; + new_c = HairpinE(u, type, sj1, si1, loopseq)+bonus+c[ij]; + } + if (new_cMAXLOOP) break; + qmin = u1+i-1+length-MAXLOOP; + if (qminMAXLOOP) continue; + si1 = (i==1)? S1[length] : S1[i-1]; + sq1 = (q==length)? S1[1] : S1[q+1]; + energy = LoopEnergy(u1, u2, type, type_2, + S1[j+1], si1, S1[p-1], sq1); + new_c = c[ij] + c[indx[q]+p] + energy; + if (new_cMLclosing; + if (fmMLclosing+P->MLintern[type]+P->dangle3[type][S1[1]]; + if (fmMLclosing+P->MLintern[type]+P->dangle3[type][S1[1]]+P->dangle5[type][S1[i]]; + if (fmdangle5[type][S1[length]]+c[indx[i]+1]+fM_d5[i+1]+P->MLclosing+P->MLintern[type]; + if (fmdangle5[type][S1[length]]+c[indx[i]+1]+P->dangle3[type][S1[i+1]]+ + fM_d5[i+2]+P->MLclosing+P->MLintern[type]; + if (fm0)?Md5i:-Md5i; + sector[s].ml = 2; + i = (Md5i>0)?Md5i+1 : -Md5i+2; /* let's backtrack fm_d5[Md5i+1] */ + for (u=i+TURN; u0)?Md3i+1:-Md3i+1; + sector[s].j = length; + sector[s].ml = 2; + i = (Md3i>0)? Md3i : -Md3i-1; /* let's backtrack fm_d3[Md3i] */ + for (u=2+TURN; u-4)) { + bonus_cnt++; + if((BP[i]==-3)&&(structure[i-1]==')')) bonus++; + if((BP[i]==-2)&&(structure[i-1]=='(')) bonus++; + if((BP[i]==-1)&&(structure[i-1]!='.')) bonus++; + } + + if(BP[i]>i) { + int l; + bonus_cnt++; + for(l=1; l<=base_pair[0].i; l++) + if((i==base_pair[l].i)&&(BP[i]==base_pair[l].j)) bonus++; + } + } + + if (bonus_cnt>bonus) fprintf(stderr,"\ncould not enforce all constraints\n"); + bonus*=BONUS; + + free(fM2); free(S); free(S1); free(BP); + + energy = Fc + bonus; /*remove bonus energies from result */ + + return (float) energy/100.; +} + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/cofold.c b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/cofold.c new file mode 100755 index 00000000..02b3706b --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/cofold.c @@ -0,0 +1,1284 @@ +/* Last changed Time-stamp: <2004-12-10 17:32:10 ivo> */ +/* + minimum free energy + RNA secondary structure prediction + + c Ivo Hofacker, Chrisoph Flamm + original implementation by + Walter Fontana + + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "params.h" + +/*@unused@*/ +static char rcsid[] UNUSED = "$Id: cofold.c,v 1.7 2004/12/10 16:32:57 ivo Exp $"; + +#define PAREN + +#define PUBLIC +#define PRIVATE static + +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define NEW_NINIO 1 /* new asymetry penalty */ +#define free_arrays free_co_arrays +#define initialize_fold initialize_cofold +#define update_fold_params update_cofold_params +PUBLIC float cofold(const char *string, char *structure); +PUBLIC void free_arrays(void); +PUBLIC void initialize_fold(int length); +PUBLIC void update_fold_params(void); +PUBLIC float *get_monomer_mfes(); +extern int logML; /* if nonzero use logarithmic ML energy in + energy_of_struct */ +extern int uniq_ML; /* do ML decomposition uniquely (for subopt) */ +/*@unused@*/ +PRIVATE void letter_structure(char *structure, int length) UNUSED; +PRIVATE void parenthesis_structure(char *structure, int length); +PRIVATE void get_arrays(unsigned int size); +/* PRIVATE void scale_parameters(void); */ +PRIVATE void make_ptypes(const short *S, const char *structure); +PRIVATE void encode_seq(const char *sequence); +PRIVATE void backtrack(const char *sequence); +PRIVATE int fill_arrays(const char *sequence); +/*@unused@*/ +inline PRIVATE int oldLoopEnergy(int i, int j, int p, int q, int type, int type_2); +inline PRIVATE int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1); +inline PRIVATE int HairpinE(int size, int type, int si1, int sj1, const char *string); +PRIVATE void free_end(int *array, int i, int start); + +#define MAXSECTORS 500 /* dimension for a backtrack array */ +#define LOCALITY 0. /* locality parameter for base-pairs */ + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) +#define SAME_STRAND(I,J) (((I)>=cut_point)||((J)cut) */ +PRIVATE int *fML; /* multi-loop auxiliary energy array */ +PRIVATE int *fM1; /* second ML array, only for subopt */ +PRIVATE int *Fmi; /* holds row i of fML (avoids jumps in memory) */ +PRIVATE int *DMLi; /* DMLi[j] holds MIN(fML[i,k]+fML[k+1,j]) */ +PRIVATE int *DMLi1; /* MIN(fML[i+1,k]+fML[k+1,j]) */ +PRIVATE int *DMLi2; /* MIN(fML[i+2,k]+fML[k+1,j]) */ +PRIVATE char *ptype; /* precomputed array of pair types */ +PRIVATE short *S, *S1; +PRIVATE int init_length=-1; + +PRIVATE char alpha[] = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz"; +#undef TURN +#define TURN 0 +extern int cut_point; /* set to first pos of second seq for cofolding */ +extern int eos_debug; /* verbose info from energy_of_struct */ + +/*--------------------------------------------------------------------------*/ +static float mfe1, mfe2; /* minimum free energies of the monomers */ +PUBLIC void initialize_fold(int length) +{ + unsigned int n; + if (length<1) nrerror("initialize_fold: argument must be greater 0"); + if (init_length>0) free_arrays(); + get_arrays((unsigned) length); + init_length=length; + + for (n = 1; n <= (unsigned) length; n++) + indx[n] = (n*(n-1)) >> 1; /* n(n-1)/2 */ + + update_fold_params(); +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int size) +{ + indx = (int *) space(sizeof(int)*(size+1)); + c = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + fML = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + if (uniq_ML) + fM1 = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + + ptype = (char *) space(sizeof(char)*((size*(size+1))/2+2)); + f5 = (int *) space(sizeof(int)*(size+2)); + fc = (int *) space(sizeof(int)*(size+2)); + cc = (int *) space(sizeof(int)*(size+2)); + cc1 = (int *) space(sizeof(int)*(size+2)); + Fmi = (int *) space(sizeof(int)*(size+1)); + DMLi = (int *) space(sizeof(int)*(size+1)); + DMLi1 = (int *) space(sizeof(int)*(size+1)); + DMLi2 = (int *) space(sizeof(int)*(size+1)); + base_pair = (struct bond *) space(sizeof(struct bond)*(1+size/2)); +} + +/*--------------------------------------------------------------------------*/ + +PUBLIC void free_arrays(void) +{ + free(indx); free(c); free(fML); free(f5); free(cc); free(cc1); + free(fc); + free(ptype); + if (uniq_ML) free(fM1); + + free(base_pair); free(Fmi); + free(DMLi); free(DMLi1);free(DMLi2); + init_length=0; +} + + +/*--------------------------------------------------------------------------*/ + +void export_cofold_arrays(int **f5_p, int **c_p, int **fML_p, int **fM1_p, + int **fc_p, int **indx_p, char **ptype_p) { + /* make the DP arrays available to routines such as subopt() */ + *f5_p = f5; *c_p = c; + *fML_p = fML; *fM1_p = fM1; + *indx_p = indx; *ptype_p = ptype; + *fc_p =fc; +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE int *BP; /* contains the structure constrainsts: BP[i] + -1: | = base must be paired + -2: < = base must be paired with j = base must be paired with j>i + -4: x = base must not pair + positive int: base is paired with int */ + +float cofold(const char *string, char *structure) { + int i, length, energy, bonus=0, bonus_cnt=0; + + length = (int) strlen(string); + if (length>init_length) initialize_fold(length); + if (fabs(P->temperature - temperature)>1e-6) update_fold_params(); + + encode_seq(string); + + BP = (int *)space(sizeof(int)*(length+2)); + make_ptypes(S, structure); + + energy = fill_arrays(string); + + backtrack(string); + +#ifdef PAREN + parenthesis_structure(structure, length); +#else + letter_structure(structure, length); +#endif + + /* check constraints */ + for(i=1;i<=length;i++) { + if((BP[i]<0)&&(BP[i]>-4)) { + bonus_cnt++; + if((BP[i]==-3)&&(structure[i-1]==')')) bonus++; + if((BP[i]==-2)&&(structure[i-1]=='(')) bonus++; + if((BP[i]==-1)&&(structure[i-1]!='.')) bonus++; + } + + if(BP[i]>i) { + int l; + bonus_cnt++; + for(l=1; l<=base_pair[0].i; l++) + if((i==base_pair[l].i)&&(BP[i]==base_pair[l].j)) bonus++; + } + } + + if (bonus_cnt>bonus) fprintf(stderr,"\ncould not enforce all constraints\n"); + bonus*=BONUS; + + free(S); free(S1); free(BP); + + energy += bonus; /*remove bonus energies from result */ + + if (backtrack_type=='C') + return (float) c[indx[length]+1]/100.; + else if (backtrack_type=='M') + return (float) fML[indx[length]+1]/100.; + else + return (float) energy/100.; +} + +PRIVATE int fill_arrays(const char *string) { + /* fill "c", "fML" and "f5" arrays and return optimal energy */ + + int i, j, k, length, energy; + int decomp, new_fML, max_separation; + int no_close, type, type_2, tt; + int bonus=0; + + length = (int) strlen(string); + + max_separation = (int) ((1.-LOCALITY)*(double)(length-2)); /* not in use */ + + for (j=1; j<=length; j++) { + Fmi[j]=DMLi[j]=DMLi1[j]=DMLi2[j]=INF; + fc[j]=0; + } + + for (j = 1; j<=length; j++) + for (i=1; i<=j; i++) { + c[indx[j]+i] = fML[indx[j]+i] = INF; + if (uniq_ML) fM1[indx[j]+i] = INF; + } + + for (i = length-TURN-1; i >= 1; i--) { /* i,j in [1..length] */ + + for (j = i+TURN+1; j <= length; j++) { + int p, q, ij; + ij = indx[j]+i; + bonus = 0; + type = ptype[ij]; + + /* enforcing structure constraints */ + if ((BP[i]==j)||(BP[i]==-1)||(BP[i]==-2)) bonus -= BONUS; + if ((BP[j]==-1)||(BP[j]==-3)) bonus -= BONUS; + if ((BP[i]==-4)||(BP[j]==-4)) type=0; + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + + if (j-i-1 > max_separation) type = 0; /* forces locality degree */ + + if (type) { /* we have a pair */ + int new_c=0, stackEnergy=INF; + /* hairpin ----------------------------------------------*/ + + if (SAME_STRAND(i,j)) { + if (no_close) new_c = FORBIDDEN; + else + new_c = HairpinE(j-i-1, type, S1[i+1], S1[j-1], string+i-1); + } + else { + if (dangles) { + if (SAME_STRAND(i,i+1)) new_c += P->dangle3[rtype[type]][S1[i+1]]; + if (SAME_STRAND(j-1,j)) new_c += P->dangle5[rtype[type]][S1[j-1]]; + } + if (type>2) new_c += P->TerminalAU; + } + + /*-------------------------------------------------------- + check for elementary structures involving more than one + closing pair. + --------------------------------------------------------*/ + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1) ; p++) { + int minq = j-i+p-MAXLOOP-2; + if (minqi+1)||(qdangle3[rtype[type]][S1[i+1]] : 0; + dj = (SAME_STRAND(j-1,j)) ? + P->dangle5[rtype[type]][S1[j-1]] : 0; + dp = (SAME_STRAND(p-1,p)) ? + P->dangle5[rtype[type_2]][S1[p-1]] : 0; + dq = (SAME_STRAND(q,q+1)) ? + P->dangle3[rtype[type_2]][S1[q+1]] : 0; + if (dangles == 2) energy = di + dj + dp + dq; + else { /* no double dangles */ + if (i+1 < p-1) energy = di + dp; + if (i+1 == p-1) energy = MIN2(di, dp); + if (q+1 < j-1) energy += dj + dq; + if (q+1 == j-1) energy += MIN2(dj, dq); + } + } + if (type>2) energy += P->TerminalAU; + if (type_2>2) energy += P->TerminalAU; + } +#else + /* duplicated code is faster than function call */ + +#endif + new_c = MIN2(energy+c[indx[q]+p], new_c); + if ((p==i+1)&&(j==q+1)) stackEnergy = energy; /* remember stack energy */ + + } /* end q-loop */ + } /* end p-loop */ + + /* multi-loop decomposition ------------------------*/ + + + if (!no_close) { + int MLenergy; + decomp = DMLi1[j-1]; + if (SAME_STRAND(i,i+1) && SAME_STRAND(j-1,j)) { + if (dangles) { + int d3, d5; + tt = rtype[type]; + d3 = P->dangle3[tt][S1[i+1]]; + d5 = P->dangle5[tt][S1[j-1]]; + if (dangles==2) /* double dangles */ + decomp += d5 + d3; + else { /* normal dangles */ + decomp = MIN2(DMLi2[j-1]+d3+P->MLbase, decomp); + decomp = MIN2(DMLi1[j-2]+d5+P->MLbase, decomp); + decomp = MIN2(DMLi2[j-2]+d5+d3+2*P->MLbase, decomp); + } + } + MLenergy = P->MLclosing+P->MLintern[type]+decomp; + new_c = MLenergy < new_c ? MLenergy : new_c; + } + + if (!SAME_STRAND(i,j)) { /* cut is somewhere in the multiloop*/ + int d3=0, d5=0; + tt = rtype[type]; + decomp = fc[i+1]+fc[j-1]; + if (SAME_STRAND(i,i+1)) d3 = P->dangle3[tt][S1[i+1]]; + if (SAME_STRAND(j-1,j)) d5 = P->dangle5[tt][S1[j-1]]; + if (dangles==2) + decomp+=d5+d3; + else { + decomp = MIN2(fc[i+2]+fc[j-1]+d3, decomp); + decomp = MIN2(fc[i+1]+fc[j-2]+d5, decomp); + decomp = MIN2(fc[i+2]+fc[j-2]+d3+d5, decomp); + } + if (type>2) decomp+=P->TerminalAU; + new_c = MIN2(new_c, decomp); + } + } /* end >> if (!no_close) << */ + + /* coaxial stacking of (i.j) with (i+1.k) or (k+1.j-1) */ + + if (dangles==3) { + decomp = INF; + for (k = i+2+TURN; k < j-2-TURN; k++) { + type_2 = ptype[indx[k]+i+1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[indx[k]+i+1]+P->stack[type][type_2]+ + fML[indx[j-1]+k+1]); + type_2 = ptype[indx[j-1]+k+1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[indx[j-1]+k+1]+P->stack[type][type_2]+ + fML[indx[k]+i+1]); + } + /* no TermAU penalty if coax stack */ + decomp += 2*P->MLintern[1] + P->MLclosing; + new_c = MIN2(new_c, decomp); + } + + new_c = MIN2(new_c, cc1[j-1]+stackEnergy); + cc[j] = new_c + bonus; + if (noLonelyPairs) + c[ij] = cc1[j-1]+stackEnergy+bonus; + else + c[ij] = cc[j]; + + } /* end >> if (pair) << */ + + else c[ij] = INF; + + + /* done with c[i,j], now compute fML[i,j] */ + /* free ends ? -----------------------------------------*/ + new_fML=INF; + if (SAME_STRAND(i-1,i)) { + if (SAME_STRAND(i,i+1)) new_fML = fML[ij+1]+P->MLbase; + if (SAME_STRAND(j-1,j)) new_fML = MIN2(fML[indx[j-1]+i]+P->MLbase, new_fML); + if (SAME_STRAND(j,j+1)) { + energy = c[ij]+P->MLintern[type]; + if (dangles==2) { /* double dangles */ + if (i>1) energy += P->dangle5[type][S1[i-1]]; + if (jdangle3[type][S1[j+1]]; + } + new_fML = MIN2(energy, new_fML); + if (uniq_ML) fM1[ij]=energy; + if ((uniq_ML)&&(SAME_STRAND(j-1,j))) + fM1[ij] = MIN2(fM1[indx[j-1]+i] + P->MLbase, energy); + } + if (dangles%2==1) { /* normal dangles */ + if (SAME_STRAND(i,i+1)) { + tt = ptype[ij+1]; /* i+1,j */ + new_fML = MIN2(c[ij+1]+P->dangle5[tt][S1[i]] + +P->MLintern[tt]+P->MLbase,new_fML); + } + if (SAME_STRAND(j-1,j)) { + tt = ptype[indx[j-1]+i]; + new_fML = MIN2(c[indx[j-1]+i]+P->dangle3[tt][S1[j]] + +P->MLintern[tt]+P->MLbase, new_fML); + } + if ((SAME_STRAND(j-1,j))&&(SAME_STRAND(i,i+1))) { + tt = ptype[indx[j-1]+i+1]; + new_fML = MIN2(c[indx[j-1]+i+1]+P->dangle5[tt][S1[i]]+ + P->dangle3[tt][S1[j]]+P->MLintern[tt]+2*P->MLbase, new_fML); + } + } + } + + /* modular decomposition -------------------------------*/ + + { + int stopp; /*loop 1 up to cut, then loop 2*/ + stopp=(cut_point>0)? (cut_point):(j-2-TURN); + for (decomp=INF, k = i+1+TURN; k0)? (cut_point):(j-2-TURN); + /* additional ML decomposition as two coaxially stacked helices */ + for (decomp = INF, k = i+1+TURN; kstack[type][type_2]); + } + k++; + for (;k <= j-2-TURN; k++) { + type = ptype[indx[k]+i]; type = rtype[type]; + type_2 = ptype[indx[j]+k+1]; type_2 = rtype[type_2]; + if (type && type_2) + decomp = MIN2(decomp, + c[indx[k]+i]+c[indx[j]+k+1]+P->stack[type][type_2]); + } + + decomp += 2*P->MLintern[1]; + +#if 0 + /* This is needed for Y shaped ML loops with coax stacking of + interior pairs, but backtracking will fail if activated */ + DMLi[j] = MIN2(DMLi[j], decomp); + if (SAME_STRAND(j-1,j)) DMLi[j] = MIN2(DMLi[j], DMLi[j-1]+P->MLbase); + if (SAME_STRAND(i,i+1)) DMLi[j] = MIN2(DMLi[j], DMLi1[j]+P->MLbase); + new_fML = MIN2(new_fML, DMLi[j]); +#endif + new_fML = MIN2(new_fML, decomp); + } + + fML[ij] = Fmi[j] = new_fML; /* substring energy */ + + } + + if (i==cut_point) + for (j=i; j<=length; j++) + free_end(fc, j, cut_point); + if (i0) { + mfe1=f5[cut_point-1]; + mfe2=fc[length]; + /* add DuplexInit, check whether duplex*/ + for (i=cut_point; i<=length; i++) { + f5[i]=MIN2(f5[i]+P->DuplexInit, fc[i]+fc[1]); + } + } + + energy = f5[length]; + if (cut_point<1) mfe1=mfe2=energy; + return energy; +} + +PRIVATE void backtrack(const char *string) { + + /*------------------------------------------------------------------ + trace back through the "c", "fc", "f5" and "fML" arrays to get the + base pairing list. No search for equivalent structures is done. + This is fast, since only few structure elements are recalculated. + ------------------------------------------------------------------*/ + struct sect { + int i; + int j; + int ml; + } + sector[MAXSECTORS]; /* backtracking sectors */ + + int i, j, k, length, energy, new; + int no_close, type, type_2, tt; + int bonus; + int s=0, b=0; + + length = strlen(string); + sector[++s].i = 1; + sector[s].j = length; + sector[s].ml = (backtrack_type=='M') ? 1 : ((backtrack_type=='C')?2:0); + + while (s>0) { + int ml, fij, fi, cij, traced, i1, j1, d3, d5, mm, p, q, jj=0; + int canonical = 1; /* (i,j) closes a canonical structure */ + i = sector[s].i; + j = sector[s].j; + ml = sector[s--].ml; /* ml is a flag indicating if backtracking is to + occur in the fML- (1) or in the f-array (0) */ + if (ml==2) { + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + + if (j < i+TURN+1) continue; /* no more pairs in this interval */ + + + if (ml==0) {fij = f5[j]; fi = f5[j-1];} + else if (ml==1) {fij = fML[indx[j]+i]; fi = fML[indx[j-1]+i]+P->MLbase;} + else /* 3 or 4 */ { + fij = fc[j]; + fi = (ml==3) ? INF : fc[j-1]; + } + if (fij == fi) { /* 3' end is unpaired */ + sector[++s].i = i; + sector[s].j = j-1; + sector[s].ml = ml; + continue; + } + + if (ml==0 || ml==4) { /* backtrack in f5 or fc[i=cut,j>cut] */ + int *ff; + ff = (ml==4) ? fc : f5; + /* j or j-1 is paired. Find pairing partner */ + for (k=j-TURN-1,traced=0; k>=i; k--) { + int cc, en; + jj = k-1; + type = ptype[indx[j-1]+k]; + if((type)&&(dangles%2==1)&&SAME_STRAND(j-1,j)) { + cc = c[indx[j-1]+k]+P->dangle3[type][S1[j]]; + if (!SAME_STRAND(k,j-1)) cc += P->DuplexInit; /*???*/ + if (type>2) cc += P->TerminalAU; + if (fij == cc + ff[k-1]) + traced=j-1; + if (k>i) { + d5 = SAME_STRAND(k-1,k) ? P->dangle5[type][S1[k-1]] : 0; + if (fij == ff[k-2] + cc + d5) { + traced=j-1; jj=k-2; + } + } + } + type = ptype[indx[j]+k]; + if (type) { + cc = c[indx[j]+k]; + if (!SAME_STRAND(k,j)) cc += P->DuplexInit; + if (type>2) cc += P->TerminalAU; + en = cc + ff[k-1]; + if (dangles==2) { + if (k>1 &&SAME_STRAND(k-1,k)) en += P->dangle5[type][S1[k-1]]; + if (jdangle3[type][S1[j+1]]; + } + if (fij == en) traced=j; + if ((dangles%2==1) && (k>1) && SAME_STRAND(k-1,k)) + if (fij == ff[k-2]+cc+P->dangle5[type][S1[k-1]]) { + traced=j; jj=k-2; + } + } + if (traced) break; + } + + if (!traced) nrerror("backtrack failed in f5 (or fc)"); + sector[++s].i = i; + sector[s].j = jj; + sector[s].ml = ml; + + i=k; j=traced; + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + else if (ml==3) { /* backtrack in fc[i1 && SAME_STRAND(i-1,i)) ? P->dangle5[type][S1[i-1]] : 0; + d3 = (SAME_STRAND(k,k+1)) ? P->dangle3[type][S1[k+1]] : 0; + en = fc[k+1]+c[indx[k]+i]; + if (type>2) en+=P->TerminalAU; + + if (dangles==2) en += d5+d3; + if (fc[i]==en) traced=i; + else if (dangles%2==1) { + int tau; + tau = (type>2) ? P->TerminalAU : 0; + if (fc[i]==fc[k+2]+c[indx[k]+i]+d3+tau) { + traced=i; jj=k+2; + } + } + } + if (traced) break; + + if (dangles%2==1) { + int tau; + type = ptype[indx[k]+i+1]; + tau = (type>2) ? P->TerminalAU : 0; + if (type) { + d5 = (SAME_STRAND(i, i+1)) ? P->dangle5[type][S1[i]] : 0; + if (fc[i] == fc[k+1]+c[indx[k]+i+1]+d5+tau) + traced=i+1; + if (kdangle3[type][S1[k+1]] : 0; + if (fc[i] == fc[k+2]+c[indx[k]+i+1]+d5+d3+tau) { + traced=i+1; jj=k+2; + } + } + } + } + if (traced) break; + } + + if (!traced) nrerror("backtrack failed in fc[] 5' of cut"); + + sector[++s].i = jj; + sector[s].j = j; + sector[s].ml = ml; + + j=k; i=traced; + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + + else { /* true multi-loop backtrack in fML */ + int cij1=INF, ci1j=INF, ci1j1=INF; + if (fML[indx[j]+i+1]+P->MLbase == fij) { /* 5' end is unpaired */ + sector[++s].i = i+1; + sector[s].j = j; + sector[s].ml = ml; + continue; + } + + tt = ptype[indx[j]+i]; + cij = c[indx[j]+i] + P->MLintern[tt]; + if (dangles==2) { /* double dangles */ + if (i>1) cij += P->dangle5[tt][S1[i-1]]; + if (jdangle3[tt][S1[j+1]]; + } + else if (dangles%2==1) { /* normal dangles */ + tt = ptype[indx[j]+i+1]; + ci1j = c[indx[j]+i+1]+P->dangle5[tt][S1[i]]+P->MLintern[tt]+P->MLbase; + tt = ptype[indx[j-1]+i]; + cij1 = c[indx[j-1]+i]+P->dangle3[tt][S1[j]]+P->MLintern[tt]+P->MLbase; + tt = ptype[indx[j-1]+i+1]; + ci1j1 = c[indx[j-1]+i+1]+P->dangle5[tt][S1[i]]+P->dangle3[tt][S1[j]] + + P->MLintern[tt]+2*P->MLbase; + } + + if ((fij==cij)||(fij==ci1j)||(fij==cij1)||(fij==ci1j1)) { + /* found a pair */ + if (fij==ci1j) i++; + else if (fij==cij1) j--; + else if (fij==ci1j1) {i++; j--;} + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + + /* find next component of multiloop */ + for (k = i+1+TURN; k <= j-2-TURN; k++) + if (fij == (fML[indx[k]+i]+fML[indx[j]+k+1])) + break; + + if ((dangles==3)&&(k>j-2-TURN)) { /* must be coax stack */ + ml = 2; + for (k = i+1+TURN; k <= j-2-TURN; k++) { + type = ptype[indx[k]+i]; type= rtype[type]; + type_2 = ptype[indx[j]+k+1]; type_2= rtype[type_2]; + if (type && type_2) + if (fij == c[indx[k]+i]+c[indx[j]+k+1]+P->stack[type][type_2]+ + 2*P->MLintern[1]) + break; + } + } + + sector[++s].i = i; + sector[s].j = k; + sector[s].ml = ml; + sector[++s].i = k+1; + sector[s].j = j; + sector[s].ml = ml; + + if (k>j-2-TURN) nrerror("backtrack failed in fML"); + continue; + } + + repeat1: + + /*----- begin of "repeat:" -----*/ + if (canonical) cij = c[indx[j]+i]; + + type = ptype[indx[j]+i]; + + bonus = 0; + + if ((BP[i]==j)||(BP[i]==-1)||(BP[i]==-2)) bonus -= BONUS; + if ((BP[j]==-1)||(BP[j]==-3)) bonus -= BONUS; + + if (noLonelyPairs) + if (cij == c[indx[j]+i]) { + /* (i.j) closes canonical structures, thus + (i+1.j-1) must be a pair */ + type_2 = ptype[indx[j-1]+i+1]; type_2 = rtype[type_2]; + cij -= P->stack[type][type_2] + bonus; + base_pair[++b].i = i+1; + base_pair[b].j = j-1; + i++; j--; + canonical=0; + goto repeat1; + } + canonical = 1; + + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + if (SAME_STRAND(i,j)) { + if (no_close) { + if (cij == FORBIDDEN) continue; + } else + if (cij == HairpinE(j-i-1, type, S1[i+1], S1[j-1],string+i-1)+bonus) + continue; + } + else { + int ee = 0; + if (dangles) { + if (SAME_STRAND(i,i+1)) ee = P->dangle3[rtype[type]][S1[i+1]]; + if (SAME_STRAND(j-1,j)) ee += P->dangle5[rtype[type]][S1[j-1]]; + } + if (type>2) ee += P->TerminalAU; + if (cij == ee) continue; + } + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1); p++) { + int minq; + minq = j-i+p-MAXLOOP-2; + if (minq= minq; q--) { + + type_2 = ptype[indx[q]+p]; + if (type_2==0) continue; + type_2 = rtype[type_2]; + if (no_closingGU) + if (no_close||(type_2==3)||(type_2==4)) + if ((p>i+1)||(qdangle3[rtype[type]][S1[i+1]] : 0; + dj = (SAME_STRAND(j-1,j)) ? P->dangle5[rtype[type]][S1[j-1]] : 0; + dp = (SAME_STRAND(p-1,p)) ? P->dangle5[rtype[type_2]][S1[p-1]] : 0; + dq = (SAME_STRAND(q,q+1)) ? P->dangle3[rtype[type_2]][S1[q+1]] : 0; + if (dangles == 2) energy = di + dj + dp + dq; + else { /* no double dangles */ + if (i+1 < p-1) energy = di + dp; + if (i+1 == p-1) energy = MIN2(di, dp); + if (q+1 < j-1) energy += dj + dq; + if (q+1 == j-1) energy += MIN2(dj, dq); + } + } + if (type>2) energy += P->TerminalAU; + if (type_2>2) energy += P->TerminalAU; + } + + new = energy+c[indx[q]+p]+bonus; + traced = (cij == new); + if (traced) { + base_pair[++b].i = p; + base_pair[b].j = q; + i = p, j = q; + goto repeat1; + } + } + } + + /* end of repeat: --------------------------------------------------*/ + + /* (i.j) must close a fake or true multi-loop */ + tt = rtype[type]; + mm = bonus+P->MLclosing+P->MLintern[tt]; + d5 = (SAME_STRAND(j-1,j) && dangles) ? P->dangle5[tt][S1[j-1]] : 0; + d3 = (SAME_STRAND(i,i+1) && dangles) ? P->dangle3[tt][S1[i+1]] : 0; + i1 = i+1; j1 = j-1; + sector[s+1].ml = sector[s+2].ml = 1; + + /* fake multi-loop */ + if (!SAME_STRAND(i,j)) { + int ii=0, jj=0, decomp=0; + decomp = fc[i+1]+fc[j-1]; + if (type>2) decomp+=P->TerminalAU; + if (dangles==2) /* double dangles */ + decomp+=d5+d3; + if (decomp==cij) ii=i+1, jj=j-1; + else { + if (dangles%2==1) { /* normal dangles */ + int tau; + tau = (type>2) ? P->TerminalAU : 0; + if (cij == fc[i+2]+fc[j-1]+d3+tau) ii=i+2, jj=j-1; + if (cij == fc[i+1]+fc[j-2]+d5+tau) ii=i+1, jj=j-2; + if (cij == fc[i+2]+fc[j-2]+d3+d5+tau) ii=i+2, jj=j-2; + } + } + if (ii) { + sector[++s].i = ii; + sector[s].j = cut_point-1; + sector[s].ml = 3; + sector[++s].i = cut_point; + sector[s].j = jj; + sector[s].ml = 4; + continue; + } + } + + /* true multi-loop */ + for (k = i+2+TURN; k < j-2-TURN; k++) { + int en; + en = fML[indx[k]+i+1]+fML[indx[j-1]+k+1]+mm; + if (dangles==2) /* double dangles */ + en += d5+d3; + if (cij == en) + break; + if (dangles%2==1) { /* normal dangles */ + if (cij == (fML[indx[k]+i+2]+fML[indx[j-1]+k+1]+mm+d3+P->MLbase)) { + i1 = i+2; + break; + } + if (cij == (fML[indx[k]+i+1]+fML[indx[j-2]+k+1]+mm+d5+P->MLbase)) { + j1 = j-2; + break; + } + if (cij == (fML[indx[k]+i+2]+fML[indx[j-2]+k+1]+mm+d3+d5+P->MLbase+P->MLbase)) { + i1 = i+2; j1 = j-2; + break; + } + } + /* coaxial stacking of (i.j) with (i+1.k) or (k.j-1) */ + /* use MLintern[1] since coax stacked pairs don't get TerminalAU */ + if (dangles==3) { + type_2 = ptype[indx[k]+i+1]; type_2 = rtype[type_2]; + if (type_2) { + en = c[indx[k]+i+1]+P->stack[type][type_2]+fML[indx[j-1]+k+1]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + ml = 2; + sector[s+1].ml = 2; + break; + } + } + type_2 = ptype[indx[j-1]+k+1]; type_2 = rtype[type_2]; + if (type_2) { + en = c[indx[j-1]+k+1]+P->stack[type][type_2]+fML[indx[k]+i+1]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + sector[s+2].ml = 2; + break; + } + } + } + } + + if (k<=j-3-TURN) { /* found the decomposition */ + sector[++s].i = i1; + sector[s].j = k; + sector[++s].i = k+1; + sector[s].j = j1; + } else { +#if 0 + /* Y shaped ML loops don't work yet */ + if (dangles==3) { + /* (i,j) must close a Y shaped ML loop with coax stacking */ + if (cij == fML[indx[j-2]+i+2] + mm + d3 + d5 + P->MLbase + P->MLbase) { + i1 = i+2; + j1 = j-2; + } else if (cij == fML[indx[j-2]+i+1] + mm + d5 + P->MLbase) + j1 = j-2; + else if (cij == fML[indx[j-1]+i+2] + mm + d3 + P->MLbase) + i1 = i+2; + else /* last chance */ + if (cij != fML[indx[j-1]+i+1] + mm + P->MLbase) + fprintf(stderr, "backtracking failed in repeat"); + /* if we arrive here we can express cij via fML[i1,j1]+dangles */ + sector[++s].i = i1; + sector[s].j = j1; + } + else +#endif + nrerror("backtracking failed in repeat"); + } + + } /* end >> while (s>0) << */ + + base_pair[0].i = b; /* save the total number of base pairs */ +} + +PRIVATE void free_end(int *array, int i, int start) { + int inc, type, energy, length, j, ii, jj; + inc = (i>start)? 1:-1; + length = S[0]; + + if (i==start) array[i]=0; + else array[i] = array[i-inc]; + if (i>start) { + ii = start; jj=i; + } else { + ii = i; jj = start; + } + for (j=start; inc*(i-j)>TURN; j+=inc) { + int d3, d5; + if (i>j) { ii = j; jj = i;} /* inc>0 */ + else { ii = i; jj = j;} /* inc<0 */ + type = ptype[indx[jj]+ii]; + if (type) { + d5 = (ii>1 && SAME_STRAND(ii-1,ii))? P->dangle5[type][S1[ii-1]]:0; + d3 = (jjdangle3[type][S1[jj+1]]:0; + + energy = c[indx[jj]+ii]; + if (type>2) energy += P->TerminalAU; + if (dangles==2) energy += d3 + d5; + array[i] = MIN2(array[i], array[j-inc]+energy); + + if (dangles%2==1) { + if (inc>0) { + if (j>1) energy += array[j-2] + d5; + } else + if (j0) {iii = ii; jjj=jj-1;} + else {iii = ii+1; jjj = jj;} + type = ptype[indx[jjj]+iii]; + if (!type) continue; + d5 = (iii>1 && SAME_STRAND(iii-1,iii)) ? + P->dangle5[type][S1[iii-1]] : 0; + d3 = (jjjdangle3[type][S1[jjj+1]] : 0; + energy = c[indx[jjj]+iii] + ((inc>0)?d3:d5); + if (type>2) energy += P->TerminalAU; + array[i] = MIN2(array[i], array[j-inc]+energy); + if (j!=start) { /* dangles on both sides */ + energy += (inc>0)?d5:d3; + array[i] = MIN2(array[i], array[j-2*inc]+energy); + } + } + } +} + +/*---------------------------------------------------------------------------*/ + +inline int HairpinE(int size, int type, int si1, int sj1, const char *string) { + int energy; + energy = (size <= 30) ? P->hairpin[size] : + P->hairpin[30]+(int)(P->lxc*log((size)/30.)); + if (tetra_loop) + if (size == 4) { /* check for tetraloop bonus */ + char tl[7]={0}, *ts; + strncpy(tl, string, 6); + if ((ts=strstr(P->Tetraloops, tl))) + energy += P->TETRA_ENERGY[(ts-P->Tetraloops)/7]; + } + if (size == 3) { + char tl[6]={0,0,0,0,0,0}, *ts; + strncpy(tl, string, 5); + if ((ts=strstr(P->Triloops, tl))) + energy += P->Triloop_E[(ts-P->Triloops)/6]; + + if (type>2) /* neither CG nor GC */ + energy += P->TerminalAU; /* penalty for closing AU GU pair */ + } + else /* no mismatches for tri-loops */ + energy += P->mismatchH[type][si1][sj1]; + + return energy; +} + +/*---------------------------------------------------------------------------*/ + +inline PRIVATE int oldLoopEnergy(int i, int j, int p, int q, int type, int type_2) { + /* compute energy of degree 2 loop (stack bulge or interior) */ + int n1, n2, m, energy; + n1 = p-i-1; + n2 = j-q-1; + + if (n1>n2) { m=n1; n1=n2; n2=m; } /* so that n2>=n1 */ + + if (n2 == 0) + energy = P->stack[type][type_2]; /* stack */ + + else if (n1==0) { /* bulge */ + energy = (n2<=MAXLOOP)?P->bulge[n2]: + (P->bulge[30]+(int)(P->lxc*log(n2/30.))); + +#if STACK_BULGE1 + if (n2==1) energy+=P->stack[type][type_2]; +#endif + } else { /* interior loop */ + + if ((n1+n2==2)&&(james_rule)) + /* special case for loop size 2 */ + energy = P->int11[type][type_2][S1[i+1]][S1[j-1]]; + else { + energy = (n1+n2<=MAXLOOP)?(P->internal_loop[n1+n2]): + (P->internal_loop[30]+(int)(P->lxc*log((n1+n2)/30.))); + +#if NEW_NINIO + energy += MIN2(MAX_NINIO, (n2-n1)*P->F_ninio[2]); +#else + m = MIN2(4, n1); + energy += MIN2(MAX_NINIO,((n2-n1)*P->F_ninio[m])); +#endif + energy += P->mismatchI[type][S1[i+1]][S1[j-1]]+ + P->mismatchI[type_2][S1[q+1]][S1[p-1]]; + } + } + return energy; +} + +/*--------------------------------------------------------------------------*/ + +inline int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1) { + /* compute energy of degree 2 loop (stack bulge or interior) */ + int nl, ns, energy; + + if (n1>n2) { nl=n1; ns=n2;} + else {nl=n2; ns=n1;} + + if (nl == 0) + return P->stack[type][type_2]; /* stack */ + + if (ns==0) { /* bulge */ + energy = (nl<=MAXLOOP)?P->bulge[nl]: + (P->bulge[30]+(int)(P->lxc*log(nl/30.))); + if (nl==1) energy += P->stack[type][type_2]; + else { + if (type>2) energy += P->TerminalAU; + if (type_2>2) energy += P->TerminalAU; + } + return energy; + } + else { /* interior loop */ + if (ns==1) { + if (nl==1) /* 1x1 loop */ + return P->int11[type][type_2][si1][sj1]; + if (nl==2) { /* 2x1 loop */ + if (n1==1) + energy = P->int21[type][type_2][si1][sq1][sj1]; + else + energy = P->int21[type_2][type][sq1][si1][sp1]; + return energy; + } + } + else if (n1==2 && n2==2) /* 2x2 loop */ + return P->int22[type][type_2][si1][sp1][sq1][sj1]; + { /* generic interior loop (no else here!)*/ + energy = (n1+n2<=MAXLOOP)?(P->internal_loop[n1+n2]): + (P->internal_loop[30]+(int)(P->lxc*log((n1+n2)/30.))); + + energy += MIN2(MAX_NINIO, (nl-ns)*P->F_ninio[2]); + + energy += P->mismatchI[type][si1][sj1]+ + P->mismatchI[type_2][sq1][sp1]; + } + } + return energy; +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE void encode_seq(const char *sequence) { + unsigned int i,l; + + l = strlen(sequence); + S = (short *) space(sizeof(short)*(l+1)); + S1= (short *) space(sizeof(short)*(l+1)); + /* S1 exists only for the special X K and I bases and energy_set!=0 */ + S[0] = S1[0] = (short) l; + + for (i=1; i<=l; i++) { /* make numerical encoding of sequence */ + S[i]= (short) encode_char(toupper(sequence[i-1])); + S1[i] = alias[S[i]]; /* for mismatches of nostandard bases */ + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void letter_structure(char *structure, int length) +{ + int n, k, x, y; + + for (n = 0; n <= length-1; structure[n++] = ' ') ; + structure[length] = '\0'; + + for (n = 0, k = 1; k <= base_pair[0].i; k++) { + y = base_pair[k].j; + x = base_pair[k].i; + if (x-1 > 0 && y+1 <= length) { + if (structure[x-2] != ' ' && structure[y] == structure[x-2]) { + structure[x-1] = structure[x-2]; + structure[y-1] = structure[x-1]; + continue; + } + } + if (structure[x] != ' ' && structure[y-2] == structure[x]) { + structure[x-1] = structure[x]; + structure[y-1] = structure[x-1]; + continue; + } + n++; + structure[x-1] = alpha[n-1]; + structure[y-1] = alpha[n-1]; + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void parenthesis_structure(char *structure, int length) +{ + int n, k; + + for (n = 0; n <= length-1; structure[n++] = '.') ; + structure[length] = '\0'; + + for (k = 1; k <= base_pair[0].i; k++) { + structure[base_pair[k].i-1] = '('; + structure[base_pair[k].j-1] = ')'; + } +} +/*---------------------------------------------------------------------------*/ + +PUBLIC void update_fold_params(void) +{ + P = scale_parameters(); + make_pair_matrix(); + if (init_length < 0) init_length=0; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void make_ptypes(const short *S, const char *structure) { + int n,i,j,k,l; + + n=S[0]; + for (k=1; kn) continue; + type = pair[S[i]][S[j]]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j': /* pairs downstream */ + for (l=j+TURN+1; l<=n; l++) ptype[indx[l]+j] = 0; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in constraint string"); + } + free(stack); + } +} + +PUBLIC void get_monomere_mfes(float *e1, float *e2) { + /*exports monomere free energies*/ + *e1 = mfe1; + *e2 = mfe2; +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/cofold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/cofold.o new file mode 100755 index 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zBFXnS!*QK-g5j_qGyF9vSJH4Chp#Xk=OZ^5j^p9m4aa!My@u~8`ED?LkkrdlhGTsA z1;bIU*9^yb^rwd7IQ)k)-ii1>$b$-$h8cdo#Cd|@81L#Zd}ViMXOrRki=F2~_$P)x zi}*80IQ(%|>33s{zK__MWb{+^bZg8ryi$0p;rLyQ^9-*O{Z)oH3%}iP zoR2?h_+rs-GrU9iyM|vR{3GFrXF}@t8>7EM^m`uCIsRQFKKlztJn_35hZ+4uiGP2i zUn%xWjs9siNa+Nlzg6^=hOZUAz;OH?N5 */ +/* Global variables for Distance-Package */ + +int edit_backtrack = 0; /* calculate aligned representation */ + +char *aligned_line[4]; /* containes the aligned string representations */ + +int cost_matrix = 0; /* 0 for usual costs, 1 for Shapiro's costs */ + diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/dist_vars.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/dist_vars.o new file mode 100755 index 0000000000000000000000000000000000000000..1c43c3526f5b1b26471637c9c10fff53fbbb6bc3 GIT binary patch literal 1744 zcma)6Ur*Ce6hB?N4k?U{`G6tDk%*2&S`pM_CKw??Fb0hYJgCXiZWpL*9cep)zW6U{ z;)9>VkK)HsUwy#eY42rsBqpBZp5OU@&b__8Zy!G1Fbsnf8D!E>Bl=#*Ju4YBs6vxu 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PUBLIC +#define PRIVATE static + +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define NEW_NINIO 1 /* new asymetry penalty */ + +PRIVATE void encode_seq(const char *s1, const char *s2); +PRIVATE char * backtrack(int i, int j); +PRIVATE void update_dfold_params(void); +PRIVATE int compare(const void *sub1, const void *sub2); + +extern int subopt_sorted; /* from subopt.c */ + +/*@unused@*/ + +#define MAXSECTORS 500 /* dimension for a backtrack array */ +#define LOCALITY 0. /* locality parameter for base-pairs */ + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) +#define MAX2(A, B) ((A) > (B) ? (A) : (B)) + +PRIVATE paramT *P = NULL; + +PRIVATE int **c; /* energy array, given that i-j pair */ +PRIVATE short *S1, *SS1, *S2, *SS2; +PRIVATE int n1,n2; /* sequence lengths */ +extern int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1); + + +PRIVATE int bonus_given = 0; +#define BONUS_SIZE 10000 + +extern int array_size_i; +extern int array_size_j; +extern int *array_i; +extern int *array_j; +extern int five_prime_length; +extern int auto_five_prime_length; + + +extern int E5p, E3p; +extern int debug_mode; + +PRIVATE int delay_free=0; +/*--------------------------------------------------------------------------*/ + + +duplexT duplexfold(const char *s1, const char *s2) { + int i, j, l1, Emin=INF, i_min=0, j_min=0; + char *struc; + duplexT mfe; + int dangle_energy = 0; + + int print_i, print_j; + + bonus_given = 0; + + if (auto_five_prime_length == 1) + { + + five_prime_length = array_size_i; + if (debug_mode) + printf ("five prime length set to array size = %i\n", five_prime_length); + } + + if (debug_mode) + { + printf ("array_size_i = %d, array_size_j=%i\n", array_size_i, array_size_j); + + printf ("array_i = [ "); + for (print_i = 0; print_i < array_size_i; print_i++) + printf ("%i ", array_i[print_i]); + printf ("]\narray_j = [ "); + for (print_j = 0; print_j < array_size_j; print_j++) + printf ("%i ", array_j[print_j]); + printf ("]\n"); + } + + n1 = (int) strlen(s1); + n2 = (int) strlen(s2); + + if ((!P) || (fabs(P->temperature - temperature)>1e-6)) + update_dfold_params(); + + c = (int **) space(sizeof(int *) * (n1+1)); + for (i=1; i<=n1; i++) c[i] = (int *) space(sizeof(int) * (n2+1)); + + encode_seq(s1, s2); + + for (i=1; i<=n1; i++) + { + + for (j=n2; j>0; j--) + { + int type, type2, E, k,l; + type = pair[S1[i]][S2[j]]; + c[i][j] = type ? P->DuplexInit : INF; + + if (!type) + { + if ( (i <= array_size_i) && (array_i[i-1] == n2-j+1) ) + printf ("ERROR: Wrong constraint given at %i, %i\n", i, j); + + continue; + } + + if (array_size_i) + { + if ( (i <= array_size_i) && (array_i[i-1] == n2-j+1) ) + { + c[i][j] -= BONUS_SIZE; + bonus_given = BONUS_SIZE; + + if (debug_mode) + printf ("Gave bonus to %i, %i\n", i, j); + } + + if ( (i <= array_size_i && (array_i[i-1] != n2-j+1) ) || + (n2-j+1 <= array_size_j && (array_j[n2-j] != i) ) ) + { + if (debug_mode > 1) + printf ("> Skipping: i=%i, j=%i\n", i,j); + + c[i][j] = INF; + continue; + } + } + + if (i>1) c[i][j] += P->dangle5[type][SS1[i-1]]; + if (jdangle3[type][SS2[j+1]]; + if (type>2) c[i][j] += P->TerminalAU; + + for (k=i-1; k>0 && k>i-MAXLOOP-2; k--) + { + for (l=j+1; l<=n2; l++) + { + if (i-k+l-j-2>MAXLOOP) break; + type2 = pair[S1[k]][S2[l]]; + + if (!type2) continue; + + E = LoopEnergy(i-k-1, l-j-1, type2, rtype[type], SS1[k+1], SS2[l-1], SS1[i-1], SS2[j+1]); + c[i][j] = MIN2(c[i][j], c[k][l]+E); + } + } + + E = c[i][j]; + + if (idangle3[rtype[type]][SS1[i+1]]; + if (j>1) E += P->dangle5[rtype[type]][SS2[j-1]]; + if (type>2) E += P->TerminalAU; + + if (E1 ) j_min--; + + l1 = strchr(struc, '&')-struc; + + /* + printf("%s %3d,%-3d : %3d,%-3d (%5.2f)\n", struc, i_min+1-l1, i_min, + j_min, j_min+strlen(struc)-l1-2, Emin*0.01); + */ + mfe.i = i_min; + mfe.j = j_min; + + if (array_size_i) Emin += bonus_given; + + mfe.energy = (float) (Emin) / 100.; + + if (five_prime_length) + { + dangle_energy = Emin - (E3p + E5p); + + if (debug_mode) + printf ("Dangle energy: %i\n", dangle_energy); + + if (i_min > five_prime_length) + E3p += dangle_energy; + else + E5p += dangle_energy; + } + + + + mfe.structure = struc; + if (!delay_free) { + for (i=1; i<=n1; i++) free(c[i]); + free(c); + free(S1); free(S2); free(SS1); free(SS2); + } + return mfe; +} + +PUBLIC duplexT *duplex_subopt(const char *s1, const char *s2, int delta, int w) { + int i,j, n1, n2, thresh, E, n_subopt=0, n_max; + char *struc; + duplexT mfe; + duplexT *subopt; + + n_max=16; + subopt = (duplexT *) space(n_max*sizeof(duplexT)); + delay_free=1; + mfe = duplexfold(s1, s2); + free(mfe.structure); + + thresh = (int) mfe.energy*100+0.1 + delta; + n1 = strlen(s1); n2=strlen(s2); + for (i=n1; i>0; i--) { + for (j=1; j<=n2; j++) { + int type; + type = pair[S2[j]][S1[i]]; + if (!type) continue; + E = c[i][j]; + if (idangle3[type][SS1[i+1]]; + if (j>1) E += P->dangle5[type][SS2[j-1]]; + if (type>2) E += P->TerminalAU; + if (E<=thresh) { + struc = backtrack(i,j); +#if 0 + int l1; + l1 = strchr(struc, '&')-struc; + printf("%s %3d,%-3d : %3d,%-3d (%5.2f)\n", struc, i+2-l1, i+1, + j-1, j+strlen(struc)-l1-3, E*0.01); +#endif + if (n_subopt+1>=n_max) { + n_max *= 2; + subopt = (duplexT *) xrealloc(subopt, n_max*sizeof(duplexT)); + } + subopt[n_subopt].i = MIN2(i+1,n1); + subopt[n_subopt].j = MAX2(j-1,1); + subopt[n_subopt].energy = E * 0.01; + subopt[n_subopt++].structure = struc; + } + } + } + + for (i=1; i<=n1; i++) free(c[i]); + free(c); + free(S1); free(S2); free(SS1); free(SS2); + delay_free=0; + + if (subopt_sorted) qsort(subopt, n_subopt, sizeof(duplexT), compare); + subopt[n_subopt].i =0; + subopt[n_subopt].j =0; + subopt[n_subopt].structure = NULL; + return subopt; +} + +PRIVATE char *backtrack(int i, int j) { + + /* backtrack structure going backwards from i, and forwards from j + return structure in bracket notation with & as separator */ + + int k, l, type, type2, E, traced, i0, j0; + char *st1, *st2, *struc, *sc1, *sc2; + + int first_time_five_prime = 1; + + int e_min; + + st1 = (char *) space(sizeof(char)*(n1+1)); + st2 = (char *) space(sizeof(char)*(n2+1)); + + sc1 = (char *) space(sizeof(char)*(n1+1)); + sc2 = (char *) space(sizeof(char)*(n2+1)); + + e_min = c[i][j]; + + if (debug_mode) + printf ("Starting backtrack at %i, %i with %i\n", i, j, c[i][j]); + + i0=MIN2(i+1,n1); j0=MAX2(j-1,1); + + while (i>0 && j<=n2) + { + E = c[i][j]; traced=0; + st1[i-1] = '('; + st2[j-1] = ')'; + + /* + sc1[i-1] = S1[i]; + sc2[j-1] = S2[j]; + */ + + type = pair[S1[i]][S2[j]]; + + if (!type) nrerror("backtrack failed in fold duplex"); + + for (k=i-1; k>0 && k>i-MAXLOOP-2; k--) + { + for (l=j+1; l<=n2; l++) + { + int LE; + if (i-k+l-j-2>MAXLOOP) break; + + type2 = pair[S1[k]][S2[l]]; + + if (!type2) continue; + + if (array_size_i) + { + if ( (k <= array_size_i && (array_i[k-1] != n2-l+1) ) || + (n2-l+1 <= array_size_j && (array_j[n2-l] != k) ) ) + { + /* printf ("Skipping in backtrack: k=%i, l=%i.\n", k, l); */ + continue; + } + } + + LE = LoopEnergy(i-k-1, l-j-1, type2, rtype[type], SS1[k+1], SS2[l-1], SS1[i-1], SS2[j+1]); + if (E == c[k][l]+LE) + { + traced=1; + i=k; j=l; + if (debug_mode) + printf ("Traced: k=%i, l=%i, E=%d.\n", k, l, E); + + if (five_prime_length) + { + if (k < five_prime_length && first_time_five_prime) + { + first_time_five_prime = 0; + E3p = e_min - E; + E5p = E + (bonus_given * (array_size_i > 0)); + + if (debug_mode) + printf ("Reached five prime border (%i) at k=%i. Thus, E3p = %i, E5p = %i\n", five_prime_length, k, E3p, E5p); + } + } + + break; + } + } + + if (traced) break; + } + + if (!traced) + { + if (i>1) E -= P->dangle5[type][SS1[i-1]]; + if (jdangle3[type][SS2[j+1]]; + if (type>2) E -= P->TerminalAU; + + if (E != P->DuplexInit - (bonus_given * (array_size_i > 0))) + { + printf ("E=%i\n", E); + nrerror("Fail2: backtrack failed in fold duplex. 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prediction + + c Ivo Hofacker, Chrisoph Flamm + original implementation by + Walter Fontana + + Vienna RNA package +*/ + +#include +#include +#include +#include +#include +#include +#include "utils.h" +#include "energy_par.h" +#include "fold_vars.h" +#include "pair_mat.h" +#include "params.h" + +/*@unused@*/ +static char rcsid[] UNUSED = "$Id: fold.c,v 1.33 2005/08/07 11:44:43 ivo Exp $"; + +#define PAREN + +#define PUBLIC +#define PRIVATE static + +#define STACK_BULGE1 1 /* stacking energies for bulges of size 1 */ +#define NEW_NINIO 1 /* new asymetry penalty */ + +PUBLIC float fold(const char *string, char *structure); +PUBLIC float energy_of_struct(const char *string, const char *structure); +PUBLIC int energy_of_struct_pt(const char *string, short *ptable, + short *s, short *s1); +PUBLIC void free_arrays(void); +PUBLIC void initialize_fold(int length); +PUBLIC void update_fold_params(void); + +PUBLIC int logML=0; /* if nonzero use logarithmic ML energy in + energy_of_struct */ +PUBLIC int uniq_ML=0; /* do ML decomposition uniquely (for subopt) */ +/*@unused@*/ +PRIVATE void letter_structure(char *structure, int length) UNUSED; +PRIVATE void parenthesis_structure(char *structure, int length); +PRIVATE void get_arrays(unsigned int size); +/* PRIVATE void scale_parameters(void); */ +PRIVATE int stack_energy(int i, const char *string); +PRIVATE int ML_Energy(int i, int is_extloop); +PRIVATE void make_ptypes(const short *S, const char *structure); +PRIVATE void encode_seq(const char *sequence); +PRIVATE void backtrack(const char *sequence, int s); +PRIVATE int fill_arrays(const char *sequence); +/*@unused@*/ +inline PRIVATE int oldLoopEnergy(int i, int j, int p, int q, int type, int type_2); +inline int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1); +inline int HairpinE(int size, int type, int si1, int sj1, const char *string); + +#define MAXSECTORS 500 /* dimension for a backtrack array */ +#define LOCALITY 0. /* locality parameter for base-pairs */ + +#define MIN2(A, B) ((A) < (B) ? (A) : (B)) +#define SAME_STRAND(I,J) (((I)>=cut_point)||((J)0) free_arrays(); + get_arrays((unsigned) length); + init_length=length; + + for (n = 1; n <= (unsigned) length; n++) + indx[n] = (n*(n-1)) >> 1; /* n(n-1)/2 */ + + update_fold_params(); +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE void get_arrays(unsigned int size) +{ + indx = (int *) space(sizeof(int)*(size+1)); + c = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + fML = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + if (uniq_ML) + fM1 = (int *) space(sizeof(int)*((size*(size+1))/2+2)); + + ptype = (char *) space(sizeof(char)*((size*(size+1))/2+2)); + f5 = (int *) space(sizeof(int)*(size+2)); + cc = (int *) space(sizeof(int)*(size+2)); + cc1 = (int *) space(sizeof(int)*(size+2)); + Fmi = (int *) space(sizeof(int)*(size+1)); + DMLi = (int *) space(sizeof(int)*(size+1)); + DMLi1 = (int *) space(sizeof(int)*(size+1)); + DMLi2 = (int *) space(sizeof(int)*(size+1)); + base_pair = (struct bond *) space(sizeof(struct bond)*(1+size/2)); +} + +/*--------------------------------------------------------------------------*/ + +void free_arrays(void) +{ + free(indx); free(c); free(fML); free(f5); free(cc); free(cc1); + free(ptype); + if (fM1) { + free(fM1); fM1=NULL; + } + + free(base_pair); base_pair=NULL; free(Fmi); + free(DMLi); free(DMLi1);free(DMLi2); + init_length=0; +} + +/*--------------------------------------------------------------------------*/ + +void export_fold_arrays(int **f5_p, int **c_p, int **fML_p, int **fM1_p, + int **indx_p, char **ptype_p) { + /* make the DP arrays available to routines such as subopt() */ + *f5_p = f5; *c_p = c; + *fML_p = fML; *fM1_p = fM1; + *indx_p = indx; *ptype_p = ptype; +} + +/*--------------------------------------------------------------------------*/ + +PRIVATE int *BP; /* contains the structure constrainsts: BP[i] + -1: | = base must be paired + -2: < = base must be paired with j = base must be paired with j>i + -4: x = base must not pair + positive int: base is paired with int */ + +float fold(const char *string, char *structure) { + int i, length, energy, bonus=0, bonus_cnt=0; + + length = (int) strlen(string); + if (length>init_length) initialize_fold(length); + if (fabs(P->temperature - temperature)>1e-6) update_fold_params(); + + encode_seq(string); + + BP = (int *)space(sizeof(int)*(length+2)); + make_ptypes(S, structure); + + energy = fill_arrays(string); + + backtrack(string, 0); + +#ifdef PAREN + parenthesis_structure(structure, length); +#else + letter_structure(structure, length); +#endif + + /* check constraints */ + for(i=1;i<=length;i++) { + if((BP[i]<0)&&(BP[i]>-4)) { + bonus_cnt++; + if((BP[i]==-3)&&(structure[i-1]==')')) bonus++; + if((BP[i]==-2)&&(structure[i-1]=='(')) bonus++; + if((BP[i]==-1)&&(structure[i-1]!='.')) bonus++; + } + + if(BP[i]>i) { + int l; + bonus_cnt++; + for(l=1; l<=base_pair[0].i; l++) + if((i==base_pair[l].i)&&(BP[i]==base_pair[l].j)) bonus++; + } + } + + if (bonus_cnt>bonus) fprintf(stderr,"\ncould not enforce all constraints\n"); + bonus*=BONUS; + + free(S); free(S1); free(BP); + + energy += bonus; /*remove bonus energies from result */ + + if (backtrack_type=='C') + return (float) c[indx[length]+1]/100.; + else if (backtrack_type=='M') + return (float) fML[indx[length]+1]/100.; + else + return (float) energy/100.; +} + +PRIVATE int fill_arrays(const char *string) { + /* fill "c", "fML" and "f5" arrays and return optimal energy */ + + int i, j, k, length, energy; + int decomp, new_fML, max_separation; + int no_close, type, type_2, tt; + int bonus=0; + + length = (int) strlen(string); + + max_separation = (int) ((1.-LOCALITY)*(double)(length-2)); /* not in use */ + + for (j=1; j<=length; j++) { + Fmi[j]=DMLi[j]=DMLi1[j]=DMLi2[j]=INF; + } + + for (j = 1; j<=length; j++) + for (i=(j>TURN?(j-TURN):1); i= 1; i--) { /* i,j in [1..length] */ + + for (j = i+TURN+1; j <= length; j++) { + int p, q, ij; + ij = indx[j]+i; + bonus = 0; + type = ptype[ij]; + + /* enforcing structure constraints */ + if ((BP[i]==j)||(BP[i]==-1)||(BP[i]==-2)) bonus -= BONUS; + if ((BP[j]==-1)||(BP[j]==-3)) bonus -= BONUS; + if ((BP[i]==-4)||(BP[j]==-4)) type=0; + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + + if (j-i-1 > max_separation) type = 0; /* forces locality degree */ + + if (type) { /* we have a pair */ + int new_c=0, stackEnergy=INF; + /* hairpin ----------------------------------------------*/ + + if (no_close) new_c = FORBIDDEN; + else + new_c = HairpinE(j-i-1, type, S1[i+1], S1[j-1], string+i-1); + + /*-------------------------------------------------------- + check for elementary structures involving more than one + closing pair. + --------------------------------------------------------*/ + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1) ; p++) { + int minq = j-i+p-MAXLOOP-2; + if (minqi+1)||(qdangle3[tt][S1[i+1]]; + d5 = P->dangle5[tt][S1[j-1]]; + if (dangles==2) /* double dangles */ + decomp += d5 + d3; + else { /* normal dangles */ + decomp = MIN2(DMLi2[j-1]+d3+P->MLbase, decomp); + decomp = MIN2(DMLi1[j-2]+d5+P->MLbase, decomp); + decomp = MIN2(DMLi2[j-2]+d5+d3+2*P->MLbase, decomp); + } + } + + MLenergy = P->MLclosing+P->MLintern[type]+decomp; + + new_c = MLenergy < new_c ? MLenergy : new_c; + } + + /* coaxial stacking of (i.j) with (i+1.k) or (k+1.j-1) */ + + if (dangles==3) { + decomp = INF; + for (k = i+2+TURN; k < j-2-TURN; k++) { + type_2 = ptype[indx[k]+i+1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[indx[k]+i+1]+P->stack[type][type_2]+ + fML[indx[j-1]+k+1]); + type_2 = ptype[indx[j-1]+k+1]; type_2 = rtype[type_2]; + if (type_2) + decomp = MIN2(decomp, c[indx[j-1]+k+1]+P->stack[type][type_2]+ + fML[indx[k]+i+1]); + } + /* no TermAU penalty if coax stack */ + decomp += 2*P->MLintern[1] + P->MLclosing; + new_c = MIN2(new_c, decomp); + } + + new_c = MIN2(new_c, cc1[j-1]+stackEnergy); + cc[j] = new_c + bonus; + if (noLonelyPairs) + c[ij] = cc1[j-1]+stackEnergy+bonus; + else + c[ij] = cc[j]; + + } /* end >> if (pair) << */ + + else c[ij] = INF; + + + /* done with c[i,j], now compute fML[i,j] */ + /* free ends ? -----------------------------------------*/ + + new_fML = fML[ij+1]+P->MLbase; + new_fML = MIN2(fML[indx[j-1]+i]+P->MLbase, new_fML); + energy = c[ij]+P->MLintern[type]; + if (dangles==2) { /* double dangles */ + energy += (i==1) ? /* works also for circfold */ + P->dangle5[type][S1[length]] : P->dangle5[type][S1[i-1]]; + /* if (jdangle3[type][S1[j+1]]; + } + new_fML = MIN2(energy, new_fML); + if (uniq_ML) + fM1[ij] = MIN2(fM1[indx[j-1]+i] + P->MLbase, energy); + + if (dangles%2==1) { /* normal dangles */ + tt = ptype[ij+1]; /* i+1,j */ + new_fML = MIN2(c[ij+1]+P->dangle5[tt][S1[i]] + +P->MLintern[tt]+P->MLbase,new_fML); + tt = ptype[indx[j-1]+i]; + new_fML = MIN2(c[indx[j-1]+i]+P->dangle3[tt][S1[j]] + +P->MLintern[tt]+P->MLbase, new_fML); + tt = ptype[indx[j-1]+i+1]; + new_fML = MIN2(c[indx[j-1]+i+1]+P->dangle5[tt][S1[i]]+ + P->dangle3[tt][S1[j]]+P->MLintern[tt]+2*P->MLbase, new_fML); + } + + /* modular decomposition -------------------------------*/ + + for (decomp = INF, k = i+1+TURN; k <= j-2-TURN; k++) + decomp = MIN2(decomp, Fmi[k]+fML[indx[j]+k+1]); + + DMLi[j] = decomp; /* store for use in ML decompositon */ + new_fML = MIN2(new_fML,decomp); + + /* coaxial stacking */ + if (dangles==3) { + /* additional ML decomposition as two coaxially stacked helices */ + for (decomp = INF, k = i+1+TURN; k <= j-2-TURN; k++) { + type = ptype[indx[k]+i]; type = rtype[type]; + type_2 = ptype[indx[j]+k+1]; type_2 = rtype[type_2]; + if (type && type_2) + decomp = MIN2(decomp, + c[indx[k]+i]+c[indx[j]+k+1]+P->stack[type][type_2]); + } + + decomp += 2*P->MLintern[1]; /* no TermAU penalty if coax stack */ +#if 0 + /* This is needed for Y shaped ML loops with coax stacking of + interior pairts, but backtracking will fail if activated */ + DMLi[j] = MIN2(DMLi[j], decomp); + DMLi[j] = MIN2(DMLi[j], DMLi[j-1]+P->MLbase); + DMLi[j] = MIN2(DMLi[j], DMLi1[j]+P->MLbase); + new_fML = MIN2(new_fML, DMLi[j]); +#endif + new_fML = MIN2(new_fML, decomp); + } + + fML[ij] = Fmi[j] = new_fML; /* substring energy */ + + } + + { + int *FF; /* rotate the auxilliary arrays */ + FF = DMLi2; DMLi2 = DMLi1; DMLi1 = DMLi; DMLi = FF; + FF = cc1; cc1=cc; cc=FF; + for (j=1; j<=length; j++) {cc[j]=Fmi[j]=DMLi[j]=INF; } + } + } + + /* calculate energies of 5' and 3' fragments */ + + f5[TURN+1]=0; + for (j=TURN+2; j<=length; j++) { + f5[j] = f5[j-1]; + type=ptype[indx[j]+1]; + if (type) { + energy = c[indx[j]+1]; + if (type>2) energy += P->TerminalAU; + if ((dangles==2)&&(jdangle3[type][S1[j+1]]; + f5[j] = MIN2(f5[j], energy); + } + type=ptype[indx[j-1]+1]; + if ((type)&&(dangles%2==1)) { + energy = c[indx[j-1]+1]+P->dangle3[type][S1[j]]; + if (type>2) energy += P->TerminalAU; + f5[j] = MIN2(f5[j], energy); + } + for (i=j-TURN-1; i>1; i--) { + type = ptype[indx[j]+i]; + if (type) { + energy = f5[i-1]+c[indx[j]+i]; + if (type>2) energy += P->TerminalAU; + if (dangles==2) { + energy += P->dangle5[type][S1[i-1]]; + if (jdangle3[type][S1[j+1]]; + } + f5[j] = MIN2(f5[j], energy); + if (dangles%2==1) { + energy = f5[i-2]+c[indx[j]+i]+P->dangle5[type][S1[i-1]]; + if (type>2) energy += P->TerminalAU; + f5[j] = MIN2(f5[j], energy); + } + } + type = ptype[indx[j-1]+i]; + if ((type)&&(dangles%2==1)) { + energy = c[indx[j-1]+i]+P->dangle3[type][S1[j]]; + if (type>2) energy += P->TerminalAU; + f5[j] = MIN2(f5[j], f5[i-1]+energy); + f5[j] = MIN2(f5[j], f5[i-2]+energy+P->dangle5[type][S1[i-1]]); + } + } + } + + return f5[length]; +} + +struct sect { + int i; + int j; + int ml; +} +static sector[MAXSECTORS]; /* stack of partial structures for backtracking */ + +#include "circfold.inc" + +PRIVATE void backtrack(const char *string, int s) { + + /*------------------------------------------------------------------ + trace back through the "c", "f5" and "fML" arrays to get the + base pairing list. No search for equivalent structures is done. + This is fast, since only few structure elements are recalculated. + ------------------------------------------------------------------*/ + + /* normally s=0. + If s>0 then s items have been already pushed onto the sector stack */ + int i, j, k, length, energy, new; + int no_close, type, type_2, tt; + int bonus; + int b=0; + + length = strlen(string); + if (s==0) { + sector[++s].i = 1; + sector[s].j = length; + sector[s].ml = (backtrack_type=='M') ? 1 : ((backtrack_type=='C')?2:0); + } + while (s>0) { + int ml, fij, fi, cij, traced, i1, j1, d3, d5, mm, p, q, jj=0; + int canonical = 1; /* (i,j) closes a canonical structure */ + i = sector[s].i; + j = sector[s].j; + ml = sector[s--].ml; /* ml is a flag indicating if backtracking is to + occur in the fML- (1) or in the f-array (0) */ + if (ml==2) { + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + + if (j < i+TURN+1) continue; /* no more pairs in this interval */ + + fij = (ml)? fML[indx[j]+i] : f5[j]; + fi = (ml)?(fML[indx[j-1]+i]+P->MLbase):f5[j-1]; + + if (fij == fi) { /* 3' end is unpaired */ + sector[++s].i = i; + sector[s].j = j-1; + sector[s].ml = ml; + continue; + } + + if (ml == 0) { /* backtrack in f5 */ + /* j or j-1 is paired. Find pairing partner */ + for (k=j-TURN-1,traced=0; k>=1; k--) { + int cc, en; + jj = k-1; + type = ptype[indx[j-1]+k]; + if((type)&&(dangles%2==1)) { + cc = c[indx[j-1]+k]+P->dangle3[type][S1[j]]; + if (type>2) cc += P->TerminalAU; + if (fij == cc + f5[k-1]) + traced=j-1; + if (k>i) + if (fij == f5[k-2] + cc + P->dangle5[type][S1[k-1]]) { + traced=j-1; jj=k-2; + } + } + type = ptype[indx[j]+k]; + if (type) { + cc = c[indx[j]+k]; + if (type>2) cc += P->TerminalAU; + en = cc + f5[k-1]; + if (dangles==2) { + if (k>1) en += P->dangle5[type][S1[k-1]]; + if (jdangle3[type][S1[j+1]]; + } + if (fij == en) traced=j; + if ((dangles%2==1) && (k>1)) + if (fij == f5[k-2]+cc+P->dangle5[type][S1[k-1]]) { + traced=j; jj=k-2; + } + } + if (traced) break; + } + + if (!traced) nrerror("backtrack failed in f5"); + sector[++s].i = 1; + sector[s].j = jj; + sector[s].ml = ml; + + i=k; j=traced; + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + else { /* trace back in fML array */ + int cij1=INF, ci1j=INF, ci1j1=INF; + if (fML[indx[j]+i+1]+P->MLbase == fij) { /* 5' end is unpaired */ + sector[++s].i = i+1; + sector[s].j = j; + sector[s].ml = ml; + continue; + } + + tt = ptype[indx[j]+i]; + cij = c[indx[j]+i] + P->MLintern[tt]; + if (dangles==2) { /* double dangles, works also for circfold */ + cij += (i==1) ? + P->dangle5[tt][S1[length]] : P->dangle5[tt][S1[i-1]]; + /* if (jdangle3[tt][S1[j+1]]; + } + else if (dangles%2==1) { /* normal dangles */ + tt = ptype[indx[j]+i+1]; + ci1j= c[indx[j]+i+1] + P->dangle5[tt][S1[i]] + P->MLintern[tt]+P->MLbase; + tt = ptype[indx[j-1]+i]; + cij1= c[indx[j-1]+i] + P->dangle3[tt][S1[j]] + P->MLintern[tt]+P->MLbase; + tt = ptype[indx[j-1]+i+1]; + ci1j1=c[indx[j-1]+i+1] + P->dangle5[tt][S1[i]] + P->dangle3[tt][S1[j]] + + P->MLintern[tt] + 2*P->MLbase; + } + + if ((fij==cij)||(fij==ci1j)||(fij==cij1)||(fij==ci1j1)) { + /* found a pair */ + if (fij==ci1j) i++; + else if (fij==cij1) j--; + else if (fij==ci1j1) {i++; j--;} + base_pair[++b].i = i; + base_pair[b].j = j; + goto repeat1; + } + + for (k = i+1+TURN; k <= j-2-TURN; k++) + if (fij == (fML[indx[k]+i]+fML[indx[j]+k+1])) + break; + + if ((dangles==3)&&(k>j-2-TURN)) { /* must be coax stack */ + ml = 2; + for (k = i+1+TURN; k <= j-2-TURN; k++) { + type = ptype[indx[k]+i]; type= rtype[type]; + type_2 = ptype[indx[j]+k+1]; type_2= rtype[type_2]; + if (type && type_2) + if (fij == c[indx[k]+i]+c[indx[j]+k+1]+P->stack[type][type_2]+ + 2*P->MLintern[1]) + break; + } + } + + sector[++s].i = i; + sector[s].j = k; + sector[s].ml = ml; + sector[++s].i = k+1; + sector[s].j = j; + sector[s].ml = ml; + + if (k>j-2-TURN) nrerror("backtrack failed in fML"); + continue; + } + + repeat1: + + /*----- begin of "repeat:" -----*/ + if (canonical) cij = c[indx[j]+i]; + + type = ptype[indx[j]+i]; + + bonus = 0; + + if ((BP[i]==j)||(BP[i]==-1)||(BP[i]==-2)) bonus -= BONUS; + if ((BP[j]==-1)||(BP[j]==-3)) bonus -= BONUS; + + if (noLonelyPairs) + if (cij == c[indx[j]+i]) { + /* (i.j) closes canonical structures, thus + (i+1.j-1) must be a pair */ + type_2 = ptype[indx[j-1]+i+1]; type_2 = rtype[type_2]; + cij -= P->stack[type][type_2] + bonus; + base_pair[++b].i = i+1; + base_pair[b].j = j-1; + i++; j--; + canonical=0; + goto repeat1; + } + canonical = 1; + + + no_close = (((type==3)||(type==4))&&no_closingGU&&(bonus==0)); + if (no_close) { + if (cij == FORBIDDEN) continue; + } else + if (cij == HairpinE(j-i-1, type, S1[i+1], S1[j-1],string+i-1)+bonus) + continue; + + for (p = i+1; p <= MIN2(j-2-TURN,i+MAXLOOP+1); p++) { + int minq; + minq = j-i+p-MAXLOOP-2; + if (minq= minq; q--) { + + type_2 = ptype[indx[q]+p]; + if (type_2==0) continue; + type_2 = rtype[type_2]; + if (no_closingGU) + if (no_close||(type_2==3)||(type_2==4)) + if ((p>i+1)||(qMLclosing+P->MLintern[tt]; + d5 = P->dangle5[tt][S1[j-1]]; + d3 = P->dangle3[tt][S1[i+1]]; + i1 = i+1; j1 = j-1; + sector[s+1].ml = sector[s+2].ml = 1; + + for (k = i+2+TURN; k < j-2-TURN; k++) { + int en; + en = fML[indx[k]+i+1]+fML[indx[j-1]+k+1]+mm; + if (dangles==2) /* double dangles */ + en += d5+d3; + if (cij == en) + break; + if (dangles%2==1) { /* normal dangles */ + if (cij == (fML[indx[k]+i+2]+fML[indx[j-1]+k+1]+mm+d3+P->MLbase)) { + i1 = i+2; + break; + } + if (cij == (fML[indx[k]+i+1]+fML[indx[j-2]+k+1]+mm+d5+P->MLbase)) { + j1 = j-2; + break; + } + if (cij == (fML[indx[k]+i+2]+fML[indx[j-2]+k+1]+mm+d3+d5+P->MLbase+P->MLbase)) { + i1 = i+2; j1 = j-2; + break; + } + } + /* coaxial stacking of (i.j) with (i+1.k) or (k.j-1) */ + /* use MLintern[1] since coax stacked pairs don't get TerminalAU */ + if (dangles==3) { + type_2 = ptype[indx[k]+i+1]; type_2 = rtype[type_2]; + if (type_2) { + en = c[indx[k]+i+1]+P->stack[type][type_2]+fML[indx[j-1]+k+1]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + ml = 2; + sector[s+1].ml = 2; + break; + } + } + type_2 = ptype[indx[j-1]+k+1]; type_2 = rtype[type_2]; + if (type_2) { + en = c[indx[j-1]+k+1]+P->stack[type][type_2]+fML[indx[k]+i+1]; + if (cij == en+2*P->MLintern[1]+P->MLclosing) { + sector[s+2].ml = 2; + break; + } + } + } + + } + if (k<=j-3-TURN) { /* found the decomposition */ + sector[++s].i = i1; + sector[s].j = k; + sector[++s].i = k+1; + sector[s].j = j1; + } else { +#if 0 + /* Y shaped ML loops fon't work yet */ + if (dangles==3) { + /* (i,j) must close a Y shaped ML loop with coax stacking */ + if (cij == fML[indx[j-2]+i+2] + mm + d3 + d5 + P->MLbase + P->MLbase) { + i1 = i+2; + j1 = j-2; + } else if (cij == fML[indx[j-2]+i+1] + mm + d5 + P->MLbase) + j1 = j-2; + else if (cij == fML[indx[j-1]+i+2] + mm + d3 + P->MLbase) + i1 = i+2; + else /* last chance */ + if (cij != fML[indx[j-1]+i+1] + mm + P->MLbase) + fprintf(stderr, "backtracking failed in repeat"); + /* if we arrive here we can express cij via fML[i1,j1]+dangles */ + sector[++s].i = i1; + sector[s].j = j1; + } + else +#endif + nrerror("backtracking failed in repeat"); + } + + } + + base_pair[0].i = b; /* save the total number of base pairs */ +} + +/*---------------------------------------------------------------------------*/ + +inline int HairpinE(int size, int type, int si1, int sj1, const char *string) { + int energy; + energy = (size <= 30) ? P->hairpin[size] : + P->hairpin[30]+(int)(P->lxc*log((size)/30.)); + if (tetra_loop) + if (size == 4) { /* check for tetraloop bonus */ + char tl[7]={0}, *ts; + strncpy(tl, string, 6); + if ((ts=strstr(P->Tetraloops, tl))) + energy += P->TETRA_ENERGY[(ts - P->Tetraloops)/7]; + } + if (size == 3) { + char tl[6]={0,0,0,0,0,0}, *ts; + strncpy(tl, string, 5); + if ((ts=strstr(P->Triloops, tl))) + energy += P->Triloop_E[(ts - P->Triloops)/6]; + + if (type>2) /* neither CG nor GC */ + energy += P->TerminalAU; /* penalty for closing AU GU pair */ + } + else /* no mismatches for tri-loops */ + energy += P->mismatchH[type][si1][sj1]; + + return energy; +} + +/*---------------------------------------------------------------------------*/ + +inline PRIVATE int oldLoopEnergy(int i, int j, int p, int q, int type, int type_2) { + /* compute energy of degree 2 loop (stack bulge or interior) */ + int n1, n2, m, energy; + n1 = p-i-1; + n2 = j-q-1; + + if (n1>n2) { m=n1; n1=n2; n2=m; } /* so that n2>=n1 */ + + if (n2 == 0) + energy = P->stack[type][type_2]; /* stack */ + + else if (n1==0) { /* bulge */ + energy = (n2<=MAXLOOP)?P->bulge[n2]: + (P->bulge[30]+(int)(P->lxc*log(n2/30.))); + +#if STACK_BULGE1 + if (n2==1) energy+=P->stack[type][type_2]; +#endif + } else { /* interior loop */ + + if ((n1+n2==2)&&(james_rule)) + /* special case for loop size 2 */ + energy = P->int11[type][type_2][S1[i+1]][S1[j-1]]; + else { + energy = (n1+n2<=MAXLOOP)?(P->internal_loop[n1+n2]): + (P->internal_loop[30]+(int)(P->lxc*log((n1+n2)/30.))); + +#if NEW_NINIO + energy += MIN2(MAX_NINIO, (n2-n1)*P->F_ninio[2]); +#else + m = MIN2(4, n1); + energy += MIN2(MAX_NINIO,((n2-n1)*P->F_ninio[m])); +#endif + energy += P->mismatchI[type][S1[i+1]][S1[j-1]]+ + P->mismatchI[type_2][S1[q+1]][S1[p-1]]; + } + } + return energy; +} + +/*--------------------------------------------------------------------------*/ + +inline int LoopEnergy(int n1, int n2, int type, int type_2, + int si1, int sj1, int sp1, int sq1) { + /* compute energy of degree 2 loop (stack bulge or interior) */ + int nl, ns, energy; + + if (n1>n2) { nl=n1; ns=n2;} + else {nl=n2; ns=n1;} + + if (nl == 0) + return P->stack[type][type_2]; /* stack */ + + if (ns==0) { /* bulge */ + energy = (nl<=MAXLOOP)?P->bulge[nl]: + (P->bulge[30]+(int)(P->lxc*log(nl/30.))); + if (nl==1) energy += P->stack[type][type_2]; + else { + if (type>2) energy += P->TerminalAU; + if (type_2>2) energy += P->TerminalAU; + } + return energy; + } + else { /* interior loop */ + if (ns==1) { + if (nl==1) /* 1x1 loop */ + return P->int11[type][type_2][si1][sj1]; + if (nl==2) { /* 2x1 loop */ + if (n1==1) + energy = P->int21[type][type_2][si1][sq1][sj1]; + else + energy = P->int21[type_2][type][sq1][si1][sp1]; + return energy; + } + } + else if (n1==2 && n2==2) /* 2x2 loop */ + return P->int22[type][type_2][si1][sp1][sq1][sj1]; + { /* generic interior loop (no else here!)*/ + energy = (n1+n2<=MAXLOOP)?(P->internal_loop[n1+n2]): + (P->internal_loop[30]+(int)(P->lxc*log((n1+n2)/30.))); + + energy += MIN2(MAX_NINIO, (nl-ns)*P->F_ninio[2]); + + energy += P->mismatchI[type][si1][sj1]+ + P->mismatchI[type_2][sq1][sp1]; + } + } + return energy; +} + + +/*---------------------------------------------------------------------------*/ + +PRIVATE void encode_seq(const char *sequence) { + unsigned int i,l; + + l = strlen(sequence); + S = (short *) space(sizeof(short)*(l+2)); + S1= (short *) space(sizeof(short)*(l+2)); + /* S1 exists only for the special X K and I bases and energy_set!=0 */ + S[0] = S1[0] = (short) l; + + for (i=1; i<=l; i++) { /* make numerical encoding of sequence */ + S[i]= (short) encode_char(toupper(sequence[i-1])); + S1[i] = alias[S[i]]; /* for mismatches of nostandard bases */ + } + /* for circular folding add first base at position n+1 */ + S[l+1] = S[1]; S1[l+1]=S1[1]; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void letter_structure(char *structure, int length) +{ + int n, k, x, y; + + for (n = 0; n <= length-1; structure[n++] = ' ') ; + structure[length] = '\0'; + + for (n = 0, k = 1; k <= base_pair[0].i; k++) { + y = base_pair[k].j; + x = base_pair[k].i; + if (x-1 > 0 && y+1 <= length) { + if (structure[x-2] != ' ' && structure[y] == structure[x-2]) { + structure[x-1] = structure[x-2]; + structure[y-1] = structure[x-1]; + continue; + } + } + if (structure[x] != ' ' && structure[y-2] == structure[x]) { + structure[x-1] = structure[x]; + structure[y-1] = structure[x-1]; + continue; + } + n++; + structure[x-1] = alpha[n-1]; + structure[y-1] = alpha[n-1]; + } +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void parenthesis_structure(char *structure, int length) +{ + int n, k; + + for (n = 0; n <= length-1; structure[n++] = '.') ; + structure[length] = '\0'; + + for (k = 1; k <= base_pair[0].i; k++) { + structure[base_pair[k].i-1] = '('; + structure[base_pair[k].j-1] = ')'; + } +} +/*---------------------------------------------------------------------------*/ + +PUBLIC void update_fold_params(void) +{ + P = scale_parameters(); + make_pair_matrix(); + if (init_length < 0) init_length=0; +} + +/*---------------------------------------------------------------------------*/ +PRIVATE short *pair_table; + +float energy_of_struct(const char *string, const char *structure) +{ + int energy; + short *ss, *ss1; + + if ((init_length<0)||(P==NULL)) update_fold_params(); + if (fabs(P->temperature - temperature)>1e-6) update_fold_params(); + + if (strlen(structure)!=strlen(string)) + nrerror("energy_of_struct: string and structure have unequal length"); + + /* save the S and S1 pointers in case they were already in use */ + ss = S; ss1 = S1; + encode_seq(string); + + pair_table = make_pair_table(structure); + + energy = energy_of_struct_pt(string, pair_table, S, S1); + + free(pair_table); + free(S); free(S1); + S=ss; S1=ss1; + return (float) energy/100.; +} + +int energy_of_struct_pt(const char *string, short * ptable, + short *s, short *s1) { + /* auxiliary function for kinfold, + for most purposes call energy_of_struct instead */ + + int i, length, energy; + + pair_table = ptable; + S = s; + S1 = s1; + + length = S[0]; + energy = backtrack_type=='M' ? ML_Energy(0, 0) : ML_Energy(0, 1); + if (eos_debug>0) + printf("External loop : %5d\n", energy); + for (i=1; i<=length; i++) { + if (pair_table[i]==0) continue; + energy += stack_energy(i, string); + i=pair_table[i]; + } + for (i=1; !SAME_STRAND(i,length); i++) { + if (!SAME_STRAND(i,pair_table[i])) { + energy+=P->DuplexInit; + break; + } + } + return energy; +} + +/*---------------------------------------------------------------------------*/ +PRIVATE int stack_energy(int i, const char *string) +{ + /* calculate energy of substructure enclosed by (i,j) */ + int ee, energy = 0; + int j, p, q, type; + + j=pair_table[i]; + type = pair[S[i]][S[j]]; + if (type==0) { + type=7; + if (eos_debug>=0) + fprintf(stderr,"WARNING: bases %d and %d (%c%c) can't pair!\n", i, j, + string[i-1],string[j-1]); + } + + p=i; q=j; + while (pq)) break; + type_2 = pair[S[q]][S[p]]; + if (type_2==0) { + type_2=7; + if (eos_debug>=0) + fprintf(stderr,"WARNING: bases %d and %d (%c%c) can't pair!\n", p, q, + string[p-1],string[q-1]); + } + /* energy += LoopEnergy(i, j, p, q, type, type_2); */ + if ( SAME_STRAND(i,p) && SAME_STRAND(q,j) ) + ee = LoopEnergy(p-i-1, j-q-1, type, type_2, + S1[i+1], S1[j-1], S1[p-1], S1[q+1]); + else + ee = ML_Energy(cut_in_loop(i), 1); + if (eos_debug>0) + printf("Interior loop (%3d,%3d) %c%c; (%3d,%3d) %c%c: %5d\n", + i,j,string[i-1],string[j-1],p,q,string[p-1],string[q-1], ee); + energy += ee; + i=p; j=q; type = rtype[type_2]; + } /* end while */ + + /* p,q don't pair must have found hairpin or multiloop */ + + if (p>q) { /* hair pin */ + if (SAME_STRAND(i,j)) + ee = HairpinE(j-i-1, type, S1[i+1], S1[j-1], string+i-1); + else + ee = ML_Energy(cut_in_loop(i), 1); + energy += ee; + if (eos_debug>0) + printf("Hairpin loop (%3d,%3d) %c%c : %5d\n", + i, j, string[i-1],string[j-1], ee); + + return energy; + } + + /* (i,j) is exterior pair of multiloop */ + while (p0) + printf("Multi loop (%3d,%3d) %c%c : %5d\n", + i,j,string[i-1],string[j-1],ee); + + return energy; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int ML_Energy(int i, int is_extloop) { + /* i is the 5'-base of the closing pair (or 0 for exterior loop) + loop is scored as ML if extloop==0 else as exterior loop + + since each helix can coaxially stack with at most one of its + neighbors we need an auxiliarry variable cx_energy + which contains the best energy given that the last two pairs stack. + energy holds the best energy given the previous two pairs do not + stack (i.e. the two current helices may stack) + We don't allow the last helix to stack with the first, thus we have to + walk around the Loop twice with two starting points and take the minimum + */ + + int energy, cx_energy, best_energy=INF; + int i1, j, p, q, u, x, type, count; + int mlintern[NBPAIRS+1], mlclosing, mlbase; + + if (is_extloop) { + for (x = 0; x <= NBPAIRS; x++) + mlintern[x] = P->MLintern[x]-P->MLintern[1]; /* 0 or TerminalAU */ + mlclosing = mlbase = 0; + } else { + for (x = 0; x <= NBPAIRS; x++) mlintern[x] = P->MLintern[x]; + mlclosing = P->MLclosing; mlbase = P->MLbase; + } + + for (count=0; count<2; count++) { /* do it twice */ + int ld5 = 0; /* 5' dangle energy on prev pair (type) */ + if ( i==0 ) { + j = pair_table[0]+1; + type = 0; /* no pair */ + } + else { + j = pair_table[i]; + type = pair[S[j]][S[i]]; if (type==0) type=7; + + if (dangles==3) { /* prime the ld5 variable */ + if (SAME_STRAND(j-1,j)) { + ld5 = P->dangle5[type][S1[j-1]]; + if ((p=pair_table[j-2]) && SAME_STRAND(j-2, j-1)) + if (P->dangle3[pair[S[p]][S[j-2]]][S1[j-1]]q */ + tt = pair[S[p]][S[q]]; if (tt==0) tt=7; + } + + energy += mlintern[tt]; + cx_energy += mlintern[tt]; + + if (dangles) { + int dang5=0, dang3=0, dang; + if ((SAME_STRAND(p-1,p))&&(p>1)) + dang5=P->dangle5[tt][S1[p-1]]; /* 5'dangle of pq pair */ + if ((SAME_STRAND(i1,i1+1))&&(i1dangle3[type][S1[i1+1]]; /* 3'dangle of previous pair */ + + switch (p-i1-1) { + case 0: /* adjacent helices */ + if (dangles==2) + energy += dang3+dang5; + else if (dangles==3 && i1!=0) { + if (SAME_STRAND(i1,p)) { + new_cx = energy + P->stack[rtype[type]][rtype[tt]]; + /* subtract 5'dangle and TerminalAU penalty */ + new_cx += -ld5 - mlintern[tt]-mlintern[type]+2*mlintern[1]; + } + ld5=0; + energy = MIN2(energy, cx_energy); + } + break; + case 1: /* 1 unpaired base between helices */ + dang = (dangles==2)?(dang3+dang5):MIN2(dang3, dang5); + if (dangles==3) { + energy = energy +dang; ld5 = dang - dang3; + /* may be problem here: Suppose + cx_energy>energy, cx_energy+dang56) ) + energy += 6*mlbase+(int)(P->lxc*log((double)u/6.)); + else + energy += mlbase*u; + /* fprintf(stderr, "\n"); */ + return energy; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE int cut_in_loop(int i) { + /* walk around the loop; return j pos of pair after cut if + cut_point in loop else 0 */ + int p, j; + p = j = pair_table[i]; + do { + i = pair_table[p]; p = i+1; + while ( pair_table[p]==0 ) p++; + } while (p!=j && SAME_STRAND(i,p)); + return SAME_STRAND(i,p) ? 0 : pair_table[p]; +} + +/*---------------------------------------------------------------------------*/ + +PRIVATE void make_ptypes(const short *S, const char *structure) { + int n,i,j,k,l; + + n=S[0]; + for (k=1; kn) continue; + type = pair[S[i]][S[j]]; + while ((i>=1)&&(j<=n)) { + if ((i>1)&&(j': /* pairs downstream */ + for (l=j+TURN+1; l<=n; l++) ptype[indx[l]+j] = 0; + break; + } + } + if (hx!=0) { + fprintf(stderr, "%s\n", structure); + nrerror("unbalanced brackets in constraint string"); + } + free(stack); + } +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/fold.o b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/lib/fold.o new file mode 100755 index 0000000000000000000000000000000000000000..7b0aff8274ecfe11e1bf698075242db19f2ff0dc GIT binary patch literal 124184 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zkyz;HJ7RuIf4_`bJSbcT!yb3Z2KQvQd */ +/* + * Ineractive Access to folding Routines + * + * c Ivo L Hofacker Vienna RNA package + */ + +#include +#include +#include +#include +#include +#include +#include "fold.h" +#include "part_func.h" +#include "fold_vars.h" +#include "PS_dot.h" +#include "utils.h" +/* @unused@ */ +static char rcsid[] = "$Id: RNAfold.c,v 1.18 2005/10/30 20:07:12 ivo Exp $"; + +#define PRIVATE static + +static char scale1[] = "....,....1....,....2....,....3....,....4"; +static char scale2[] = "....,....5....,....6....,....7....,....8"; + +PRIVATE void usage(void); + +/*--------------------------------------------------------------------------*/ + +int +main(int argc, char *argv[]) +{ + char *string, *line; + char *structure = NULL, *cstruc = NULL; + char *ParamFile = NULL; + char *ns_bases = NULL, *c; + int i, length, l, sym, r; + double energy, min_en; + double kT, sfact = 1.07; + int noconv = 0; + + float dG2; + double dG0, dG1, ddG, P; + + string = NULL; + for (i = 1; i < argc; i++) { + if (argv[i][0] == '-') + switch (argv[i][1]) { + case 'T': + if (argv[i][2] != '\0') + usage(); + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%lf", &temperature); + if (!r) + usage(); + break; + case 'n': + if (strcmp(argv[i], "-noGU") == 0) + noGU = 1; + if (strcmp(argv[i], "-noCloseGU") == 0) + no_closingGU = 1; + if (strcmp(argv[i], "-noLP") == 0) + noLonelyPairs = 1; + if (strcmp(argv[i], "-nsp") == 0) { + if (i == argc - 1) + usage(); + ns_bases = argv[++i]; + } + if (strcmp(argv[i], "-noconv") == 0) + noconv = 1; + break; + case '4': + tetra_loop = 0; + break; + case 'e': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%d", &energy_set); + if (!r) + usage(); + break; + case 'S': + if (i == argc - 1) + usage(); + r = sscanf(argv[++i], "%lf", &sfact); + if (!r) + usage(); + break; + case 'd': + dangles = 0; + if (argv[i][2] != '\0') { + r = sscanf(argv[i] + 2, "%d", &dangles); + if (r != 1) + usage(); + } + break; + case 'P': + if (i == argc - 1) + usage(); + ParamFile = argv[++i]; + break; + default: + usage(); + } + } + + if (ParamFile != NULL) + read_parameter_file(ParamFile); + + if (ns_bases != NULL) { + nonstandards = space(33); + c = ns_bases; + i = sym = 0; + if (*c == '-') { + sym = 1; + c++; + } + while (*c != '\0') { + if (*c != ',') { + nonstandards[i++] = *c++; + nonstandards[i++] = *c; + if ((sym) && (*c != *(c - 1))) { + nonstandards[i++] = *c; + nonstandards[i++] = *(c - 1); + } + } + c++; + } + } + + /* Some global parameters for the folding routines */ + do_backtrack = 0; + dangles = 2; + fold_constrained = 0; + + /* main loop: continue until end of file */ + + do { + + /* Read and prepare sequence and constraint ***************************/ + + if ((line = get_line(stdin)) == NULL) + break; + + string = (char *) space(strlen(line) + 1); + (void) sscanf(line, "%s", string); + free(line); + length = (int) strlen(string); + + structure = (char *) space((unsigned) length + 1); + + /* Always read folding constraint */ + if ((cstruc = get_line(stdin)) == NULL) + fprintf(stderr, "RNAdGG error: constraints missing\n"); + + if ((line = get_line(stdin)) == NULL) + fprintf (stderr, "RNAdGG error: dG2 missing\n"); + else + { + sscanf (line, "%f", &dG2); + free (line); + } + + for (l = 0; l < length; l++) { + string[l] = toupper(string[l]); + if (!noconv && string[l] == 'T') + string[l] = 'U'; + } + + /* Fold with no constraint ********************************************/ + + min_en = fold(string, structure); + printf ("%s\t", structure); + + kT = (temperature + 273.15) * 1.98717 / 1000.; /* in Kcal */ + pf_scale = exp(-(sfact * min_en) / kT / length); + init_pf_fold(length); + + dG0 = pf_fold(string, structure); + + free_pf_arrays(); + + /* Fold with constraint ***********************************************/ + + fold_constrained = 1; + strncpy(structure, cstruc, length + 1); + + min_en = fold(string, structure); + printf ("%s\t", structure); + + pf_scale = exp(-(sfact * min_en) / kT / length); + init_pf_fold(length); + + strncpy(structure, cstruc, length + 1); + dG1 = pf_fold(string, structure); + + free_pf_arrays(); + + /* Calculate and output ***********************************************/ + + ddG = dG1 + dG2 - dG0; + P = 1 / ( 1 + exp(ddG / kT) ); /* Probability of being bound */ + + printf ("%5.2f\t%5.2f\t%5.2f\t%5.2f\t%g\n", dG0, dG1, dG2, ddG, P); + + /* Free everything */ + + if (cstruc != NULL) + free(cstruc); + if (length >= 2000) + free(base_pair); + (void) fflush(stdout); + free(string); + free(structure); + } while (1); + return 0; +} + +PRIVATE void +usage(void) +{ + nrerror("usage:\n" + "RNAfold [-p[0]] [-C] [-T temp] [-4] [-d[2|3]] [-noGU] [-noCloseGU]\n" + " [-noLP] [-e e_set] [-P paramfile] [-nsp pairs] [-S scale]\n" + " [-noconv] \n"); +} diff --git a/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAddG4 b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Progs/RNAddG4 new file mode 100755 index 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mode 100755 index 00000000..6e6ab568 --- /dev/null +++ b/modules/local/pita/templates/Bin/ViennaRNA/ViennaRNA-1.6/Perl/RNAfold.cgi @@ -0,0 +1,386 @@ +#!/usr/bin/perl +# -*-Perl-*- +# Last changed Time-stamp: <2002-11-19 15:40:22 ivo> +# CGI script for a Web-based RNA fold server +# you need to have the perl5 RNA module installed +# that comes as part of the Vienna RNA package + +use strict; +use CGI qw/ :standard /; +use CGI::Carp qw(fatalsToBrowser); +use HTML::Entities; +use URI::Escape; +use RNA; +use Chart::Lines; +use vars qw/$hdir $maxlength $ssv_home $ssv_url $paramdir $serverroot/; + +# please configure these variables for your site + +$paramdir = '/var/www/RNA'; # directory where parameters files etc are stored +$serverroot = '/u/html'; # where your web pages lie +$hdir = "/RNAfold_dir"; # output directory (relative to $serverroot) +$maxlength = 500; # only process sequences up to this length +$ssv_home = "http://smi-web.stanford.edu/projects/helix/sstructview/home.html"; +$ssv_url = "/~ivo/RNA/SStructView.zip"; + +my $query = new CGI; + +if ($query->param) { + &do_work($query); +} else { + &print_header($query); +} + +&print_tail; +print $query->end_html,"\n"; + +sub print_header { + my($query, $cookie) = @_; + if ($cookie) { + print $query->header(-expires=>'+1m', + -cookie=>$cookie); + } else { + print $query->header(-expires=>'+1m'); + } + print $query->start_html(-title=>"RNAfold input form", + -author=>'ivo@tbi.univie.ac.at', + -BGCOLOR=>'#f8f8ff'); + print "\n

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