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Add (optionally) information on butyrate producers to rowData in importing the taxonomic abundances #621

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antagomir opened this issue Aug 6, 2024 · 0 comments

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antagomir commented Aug 6, 2024

The following taxa are identified as key butyrate producers (reference: Kullberg et al. 2024).
"Butyricimonas", "Odoribacter", "Alistipes", "Eubacterium", "Anaerostipes","Butyrivibrio", "Coprococcus_2", "Coprococcus_3", "Roseburia", "Shuttleworthia", "Butyricicoccus", "Faecalibacterium", "Flavonifractor", "Pseudoflavonifractor", "Oscillibacter", "Ruminococcus_2", "Subdoligranulum"

These can be mapped to the given taxonomy (manually) and could be provided as an optional rowData field with the metaphlan, GG2 etc importers, or as an additional post-import enrichment function. This can be useful for some data interpretation and analyses.

On the other hand, such manual listing will remain controversial and a more customized utility package might be better for such purpose. However, mia could provide a suitable initial home for testing also this kind approaches for data enrichment.

Reference:

Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: Results from two observational, population-based microbiome studies
Kullberg R, Wikki I, Haak B, Kauko A, Galenkamp H, Peters-Sengers H, Butler J, Havulinna A, Palmu J, McDonald D, Benchraka C, Abdel-Aziz M, Prins M, Maitland van der Zee A, Born B, Jousilahti P, Vos W, Salomaa V, Knight R, Lahti L, Nieuwdorp M, Niiranen T & Wiersinga W.
The Lancet Microbe 2024
https://doi.org/10.1016/S2666-5247(24)00079-X

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