diff --git a/README.md b/README.md index f7b6a70..c15db09 100644 --- a/README.md +++ b/README.md @@ -6,7 +6,7 @@ > A tool to predict the sequencing library type from the base composition of a supplied FastQ file. -For further information, detailed installation instructions and FAQs visit the [documentation pages](https://kartva.github.io/Librarian/). For an overview of some of the technical work that went into creating Librarian, have a look at [a presentation I made when interviewing at Neuralink](Librarian Technical Presentation.pdf) +For further information, detailed installation instructions and FAQs visit the [documentation pages](https://kartva.github.io/Librarian/). For an overview of some of the technical work that went into creating Librarian, have a look at [a presentation I made when interviewing at Neuralink](./Librarian%20Technical%20Presentation.pdf) Reads from high throughput sequencing experiments show base compositions that are characteristic for their library type. For example, data from ATAC-seq, RNA-seq and WGBS-seq libraries show markedly different distributions of G, A, C and T across the reads. Librarian makes use of different composition signatures for library quality control: Test library compositions are extracted and compared against previously published data sets from **mouse** and **human**.