diff --git a/prody/apps/prody_apps/prody_select.py b/prody/apps/prody_apps/prody_select.py index eba70f59f..ada1e9e49 100644 --- a/prody/apps/prody_apps/prody_select.py +++ b/prody/apps/prody_apps/prody_select.py @@ -35,7 +35,7 @@ def prody_select(selstr, *pdbs, **kwargs): prefix = kwargs.get('prefix', None) suffix = kwargs.get('suffix', '_selected') output = kwargs.get('output', None) - altloc = kwargs.get('altloc', None) + altloc = kwargs.get('altloc', 'all') for pdb in pdbs: pdb = parsePDB(pdb, altloc=altloc) @@ -83,7 +83,7 @@ def addCommand(commands): type=str, help=('output filename prefix (default: PDB filename)')) group.add_argument('-L', '--altloc', dest='altloc', metavar='STR', - type=str, help=('altloc (default: None (take all))')) + type=str, default='all', help=('altloc (default: %(default)s)')) group.add_argument('-x', '--suffix', dest='suffix', metavar='STR', type=str, default='_selected', diff --git a/prody/atomic/atom.py b/prody/atomic/atom.py index dd0f97462..6fdf28936 100644 --- a/prody/atomic/atom.py +++ b/prody/atomic/atom.py @@ -94,6 +94,27 @@ def setCoords(self, coords): self._ag._coords[acsi, self._index] = coords self._ag._setTimeStamp(acsi) + def getAnisou(self): + """Returns a copy of anisotropic temperature factors of the atom from the active coordinate + set.""" + + if self._ag._anisous is not None: + return self._ag._anisous[self.getACSIndex(), self._index].copy() + + def _getAnisou(self): + """Returns a view of anisotropic temperature factors of the atom from the active coordinate + set.""" + + if self._ag._anisous is not None: + return self._ag._anisous[self.getACSIndex(), self._index] + + def setAnisou(self, anisou): + """Set anisotropic temperature factors of the atom in the active coordinate set.""" + + acsi = self.getACSIndex() + self._ag._anisous[acsi, self._index] = anisou + self._ag._setTimeStamp(acsi) + def getCoordsets(self, indices=None): """Returns a copy of coordinate set(s) at given *indices*.""" diff --git a/prody/atomic/atomgroup.py b/prody/atomic/atomgroup.py index c80f67614..5bd5bbc59 100644 --- a/prody/atomic/atomgroup.py +++ b/prody/atomic/atomgroup.py @@ -9,7 +9,8 @@ from prody import LOGGER, PY2K from prody.kdtree import KDTree -from prody.utilities import checkCoords, rangeString, getDistance, copy +from prody.utilities import (checkCoords, checkAnisous, + rangeString, getDistance, copy) from .atomic import Atomic from .fields import ATOMIC_FIELDS, READONLY @@ -130,7 +131,7 @@ class AtomGroup(Atomic): '_donors', '_acceptors', '_nbexclusions', '_crossterms', '_cslabels', '_acsi', '_n_csets', '_data', '_fragments', '_flags', '_flagsts', '_subsets', - '_msa', '_sequenceMap'] + '_msa', '_sequenceMap', '_anisous'] def __init__(self, title='Unnamed'): @@ -170,6 +171,7 @@ def __init__(self, title='Unnamed'): self._subsets = None self._msa = None self._sequenceMap = None + self._anisous = None def __repr__(self): @@ -238,12 +240,20 @@ def __add__(self, other): if self._n_csets: if self._n_csets == other._n_csets: new.setCoords(np.concatenate((self._coords, other._coords), 1)) + this = self._anisous + that = other._anisous + if this is not None and that is not None: + if (isinstance(this, np.ndarray) and isinstance(that, np.ndarray) + and len(this) > 0 and len(that) > 0): + new.setAnisous(np.concatenate((self._anisous, other._anisous), 1)) if self._n_csets > 1: LOGGER.info('All {0} coordinate sets are copied to ' '{1}.'.format(self._n_csets, new.getTitle())) else: new.setCoords(np.concatenate((self._getCoords(), other._getCoords()))) + new.setAnisous(np.concatenate((self.getAnisous(), + other.getAnisous()))) LOGGER.info('Active coordinate sets are copied to {0}.' .format(new.getTitle())) elif other._n_csets: @@ -565,7 +575,101 @@ def _setCoords(self, coords, label='', overwrite=False): self._setTimeStamp(acsi) self._cslabels[acsi] = str(label) - def addCoordset(self, coords, label=None): + def getAnisous(self): + """Returns a copy of anisotropic temperature factors from active coordinate set.""" + + if self._anisous is not None: + return self._anisous[self._acsi].copy() + + def _getAnisous(self): + """Returns a view of anisotropic temperature factors from active coordinate set.""" + + if self._anisous is not None: + return self._anisous[self._acsi] + + def setAnisous(self, anisous, label=''): + """Set anisotropic temperature factors of atoms. *anisous* may be any array like object + or an object instance with :meth:`getAnisous` method. If the shape of + anisou array is ``(n_csets > 1, n_atoms, 3)``, it will replace all + coordinate sets and the active coordinate set index will reset to + zero. This situation can be avoided using :meth:`addCoordset`. + If shape of *coords* is ``(n_atoms, 3)`` or ``(1, n_atoms, 3)``, it + will replace the active coordinate set. *label* argument may be used + to label coordinate set(s). *label* may be a string or a list of + strings length equal to the number of coordinate sets.""" + + atoms = anisous + try: + if self._anisous is None and hasattr(atoms, '_getAnisous'): + anisous = atoms._getAnisous() + else: + anisous = atoms.getAnisous() + except AttributeError: + if self._anisous is None: + anisous = np.array(anisous) + else: + if anisous is None: + raise ValueError('anisous of {0} are not set' + .format(str(atoms))) + + try: + checkAnisous(anisous, csets=True, dtype=(float, np.float32)) + except TypeError: + raise TypeError('anisous must be a numpy array or an ' + 'object with `getAnisous` method') + + self._setAnisous(anisous, label=label) + + def _setAnisous(self, anisous, label='', overwrite=False): + """Set anisotropic temperature factors without data type checking. + *anisous* must be a :class:`~numpy.ndarray`, but may have data type + other than :class:`~numpy.float64`, e.g. :class:`~numpy.float32`. + *label* argument may be used to label coordinate sets. *label* may be + a string or a list of strings length equal to the number of + coordinate sets.""" + + n_atoms = self._n_atoms + if n_atoms: + if anisous.shape[-2] != n_atoms: + raise ValueError('anisous array has incorrect number of atoms') + else: + self._n_atoms = n_atoms = anisous.shape[-2] + + ndim = anisous.ndim + shape = anisous.shape + if self._anisous is None or overwrite or (ndim == 6 and shape[0] > 1): + if ndim == 2: + self._anisous = anisous.reshape((1, n_atoms, 6)) + self._cslabels = [str(label)] + self._n_csets = n_csets = 1 + + else: + self._anisous = anisous + self._n_csets = n_csets = shape[0] + + if isinstance(label, list): + if len(label) == n_csets: + self._cslabels = list(label) + + else: + self._cslabels = [''] * n_csets + LOGGER.warn('Number of labels does not match number ' + 'of coordinate sets.') + else: + self._cslabels = [str(label)] * n_csets + self._acsi = 0 + self._setTimeStamp() + + else: + acsi = self._acsi + if ndim == 2: + self._anisous[acsi] = anisous + else: + self._anisous[acsi] = anisous[0] + self._setTimeStamp(acsi) + self._cslabels[acsi] = str(label) + + def addCoordset(self, coords, label=None, anisous=None): """Add a coordinate set. *coords* argument may be an object with :meth:`getCoordsets` method.""" @@ -594,8 +698,13 @@ def addCoordset(self, coords, label=None): if coords.ndim == 2: coords = coords.reshape((1, n_atoms, 3)) + if anisous is not None and anisous.ndim == 2: + anisous = anisous.reshape((1, n_atoms, 6)) + diff = coords.shape[0] self._coords = np.concatenate((self._coords, coords), axis=0) + if anisous is not None and self._anisous is not None: + self._anisous = np.concatenate((self._anisous, anisous/10000), axis=0) self._n_csets = self._coords.shape[0] timestamps = self._timestamps self._timestamps = np.zeros(self._n_csets) diff --git a/prody/atomic/fields.py b/prody/atomic/fields.py index 2dd3288c7..26b7fa106 100644 --- a/prody/atomic/fields.py +++ b/prody/atomic/fields.py @@ -123,8 +123,6 @@ def getDocstr(self, meth, plural=True, selex=True): 'altloc': Field('altloc', DTYPE + '1', doc='alternate location indicator', selstr=('altloc A B', 'altloc _'),), - 'anisou': Field('anisou', float, doc='anisotropic temperature factor', - ndim=2), 'chain': Field('chain', DTYPE + '6', doc='chain identifier', meth='Chid', none=HVNONE, synonym='chid', selstr=('chain A', 'chid A B C', 'chain _')), diff --git a/prody/atomic/select.py b/prody/atomic/select.py index a58ad749e..9a801be19 100644 --- a/prody/atomic/select.py +++ b/prody/atomic/select.py @@ -2424,3 +2424,10 @@ def _getCoords(self): if self._coords is None: self._coords = self._atoms._getCoords() return self._coords + + def _getAnisous(self): + """Returns anisotropic temperature factors of atoms.""" + + if self._anisous is None: + self._anisous = self._atoms._getAnisous() + return self._anisous diff --git a/prody/atomic/subset.py b/prody/atomic/subset.py index b6fc466df..067ab65c2 100644 --- a/prody/atomic/subset.py +++ b/prody/atomic/subset.py @@ -63,6 +63,15 @@ def getCoords(self): _getCoords = getCoords + def getAnisous(self): + """Returns a copy of anisotropic temperature factors from the active coordinate set.""" + + if self._ag._anisous is not None: + # Since this is not slicing, a view is not returned + return self._ag._anisous[self.getACSIndex(), self._indices] + + _getAnisous = getAnisous + def setCoords(self, coords): """Set coordinates in the active coordinate set.""" @@ -70,6 +79,13 @@ def setCoords(self, coords): self._ag._coords[self.getACSIndex(), self._indices] = coords self._ag._setTimeStamp(self.getACSIndex()) + def setAnisous(self, anisous): + """Set anisotropic temperature factors in the active coordinate set.""" + + if self._ag._anisous is not None: + self._ag._anisous[self.getACSIndex(), self._indices] = anisous + self._ag._setTimeStamp(self.getACSIndex()) + def getCoordsets(self, indices=None): """Returns coordinate set(s) at given *indices*, which may be an integer or a list/array of integers.""" diff --git a/prody/database/__init__.py b/prody/database/__init__.py index fb523f789..87a736d32 100644 --- a/prody/database/__init__.py +++ b/prody/database/__init__.py @@ -10,8 +10,7 @@ * :func:`.fetchPfamMSA` - download MSA files * :func:`.searchPfam` - search for domain families of a protein - -.. _Pfam: http://pfam.sanger.ac.uk/ +.. _Pfam: https://www.ebi.ac.uk/interpro/entry/pfam/ UniProt ======== @@ -70,7 +69,14 @@ .. _GOA: https://www.ebi.ac.uk/GOA/ +Interpro +==== + +The following functions can be used to search and retrieve Pfam_ data: + + * :func:`.searchInterpro` - search for domain families of a protein +.. _Pfam: https://www.ebi.ac.uk/interpro/ """ __all__ = [] @@ -98,3 +104,7 @@ from . import quartataweb from .quartataweb import * __all__.extend(quartataweb.__all__) + +from . import interpro +from .interpro import * +__all__.extend(interpro.__all__) diff --git a/prody/database/interpro.py b/prody/database/interpro.py new file mode 100644 index 000000000..fe2d786af --- /dev/null +++ b/prody/database/interpro.py @@ -0,0 +1,102 @@ +# -*- coding: utf-8 -*- +"""This module defines functions for interfacing Interpro database.""" + +__author__ = 'James Krieger' + +import json +from os.path import isfile +from prody import LOGGER, PY3K + +__all__ = ['searchInterpro'] + +prefix = 'https://www.ebi.ac.uk/interpro/wwwapi/entry/' + +def searchInterpro(query, **kwargs): + """Returns Interpro search results in a list of dictionaries. + + Matching family accessions as keys will map to various properties, + including start and end residue positions. + + :arg query: UniProt ID or PDB identifier with or without a + chain identifier, e.g. ``'1mkp'`` or ``'1mkpA'``. + UniProt ID of the specified chain, or the first + protein chain will be used for searching the Pfam database + :type query: str + + :arg timeout: timeout for blocking connection attempt in seconds, default + is 60 + :type timeout: int + """ + import requests + + LOGGER.timeit('_interpro') + timeout = int(kwargs.get('timeout', 60)) + + if len(query) == 4: + url = prefix + "all/structure/pdb/" + query + + elif len(query) == 5: + accession = None + + from prody import parsePDBHeader + try: + polymers = parsePDBHeader(query[:4], 'polymers') + except Exception as err: + raise ValueError('failed to parse header for {0} ({1})' + .format(query[:4], str(err))) + + chid = query[4:].upper() + + for poly in polymers: + if chid and poly.chid != chid: + continue + for dbref in poly.dbrefs: + if dbref.database != 'UniProt': + continue + accession = dbref.accession + LOGGER.info('UniProt accession {0} for {1} chain ' + '{2} will be used.' + .format(accession, query[:4], poly.chid)) + break + if accession is not None: + break + + if accession is None: + raise ValueError('A UniProt accession for PDB {0} could not be ' + 'parsed.'.format(repr(query))) + else: + url = prefix + "all/protein/uniprot/" + accession + + else: + url = prefix + "all/protein/uniprot/" + query + + LOGGER.debug('Retrieving Interpro search results: ' + url) + result = None + sleep = 2 + while LOGGER.timing('_interpro') < timeout: + try: + result = requests.get(url, verify=False).content + except Exception: + pass + else: + if result not in ['PEND','RUN']: + break + + sleep = 20 if int(sleep * 1.5) >= 20 else int(sleep * 1.5) + LOGGER.sleep(int(sleep), '. Trying to reconnect...') + + if not result: + raise IOError('Interpro search timed out or failed to parse results, ' + ' check URL: ' + url) + else: + LOGGER.report('Interpro search completed in %.2fs.', '_interpro') + + if PY3K: + result = result.decode() + + try: + result = json.loads(result) + except Exception as err: + raise ValueError('failed to parse results as json, check URL: ' + url) + + return result["results"] diff --git a/prody/database/pfam.py b/prody/database/pfam.py index c8c01d583..f60654eac 100644 --- a/prody/database/pfam.py +++ b/prody/database/pfam.py @@ -1,7 +1,7 @@ # -*- coding: utf-8 -*- """This module defines functions for interfacing Pfam database.""" -__author__ = 'Anindita Dutta, Ahmet Bakan, Cihan Kaya' +__author__ = 'Anindita Dutta, Ahmet Bakan, Cihan Kaya, James Krieger' import re from numbers import Integral @@ -22,6 +22,7 @@ import urllib import urllib2 +import json __all__ = ['searchPfam', 'fetchPfamMSA', 'parsePfamPDBs'] @@ -29,186 +30,78 @@ SELEX = 'selex' STOCKHOLM = 'stockholm' -DOWNLOAD_FORMATS = set(['seed', 'full', 'ncbi', 'metagenomics', - 'rp15', 'rp35', 'rp55', 'rp75', 'uniprot']) +DOWNLOAD_FORMATS = set(['seed', 'full', 'uniprot', + #'ncbi', 'metagenomics', + #'rp15', 'rp35', 'rp55', 'rp75' + ]) FORMAT_OPTIONS = ({'format': set([FASTA, SELEX, STOCKHOLM]), 'order': set(['tree', 'alphabetical']), 'inserts': set(['lower', 'upper']), 'gaps': set(['mixed', 'dots', 'dashes', 'none'])}) -MINSEQLEN = 16 - -old_prefix = 'https://pfam.xfam.org/' -prefix = 'https://pfam-legacy.xfam.org/' +prefix = 'https://www.ebi.ac.uk/interpro/wwwapi/entry/' def searchPfam(query, **kwargs): """Returns Pfam search results in a dictionary. Matching Pfam accession as keys will map to evalue, alignment start and end residue positions. - :arg query: UniProt ID, PDB identifier, a protein sequence, or a sequence - file. Sequence queries must not contain without gaps and must be at - least 16 characters long + :arg query: UniProt ID or PDB identifier with or without a + chain identifier, e.g. ``'1mkp'`` or ``'1mkpA'``. + UniProt ID of the specified chain, or the first + protein chain will be used for searching the Pfam database :type query: str :arg timeout: timeout for blocking connection attempt in seconds, default is 60 :type timeout: int - - *query* can also be a PDB identifier, e.g. ``'1mkp'`` or ``'1mkpA'`` with - chain identifier. UniProt ID of the specified chain, or the first - protein chain will be used for searching the Pfam database.""" + """ import requests - if isfile(query): - from prody.sequence import MSAFile - try: - seq = next(MSAFile(query)) - except: - with openFile(query) as inp: - seq = ''.join(inp.read().split()) - else: - seq = seq[0][1] - if not seq.isalpha(): - raise ValueError('could not parse a sequence without gaps from ' + - query) - else: - seq = ''.join(query.split()) + seq = ''.join(query.split()) import xml.etree.cElementTree as ET LOGGER.timeit('_pfam') timeout = int(kwargs.get('timeout', 60)) - if len(seq) >= MINSEQLEN: - if not seq.isalpha(): - raise ValueError(repr(seq) + ' is not a valid sequence') - fseq = '>Seq\n' + seq - parameters = { 'hmmdb' : 'pfam', 'seq': fseq } - enc_params = urllib.urlencode(parameters).encode('utf-8') - request = urllib2.Request('https://www.ebi.ac.uk/Tools/hmmer/search/hmmscan', enc_params) - - results_url = urllib2.urlopen(request).geturl() - - #res_params = { 'output' : 'xml' } - res_params = { 'format' : 'tsv' } - enc_res_params = urllib.urlencode(res_params) - #modified_res_url = results_url + '?' + enc_res_params - modified_res_url = results_url.replace('results','download') + '?' + enc_res_params - - result_request = urllib2.Request(modified_res_url) - # url = ( urllib2.urlopen(request).geturl() + '?output=xml') - LOGGER.debug('Submitted Pfam search for sequence "{0}...".' - .format(seq[:MINSEQLEN])) + if len(seq) <= 5: + accession = None + from prody import parsePDBHeader try: - #xml = urllib2.urlopen(result_request).read() - tsv = urllib2.urlopen(result_request).read() - # openURL(url, timeout=timeout).read() - except: - raise ValueError('No matching Pfam domains were found.') - - # try: - # root = ET.XML(xml) - # except Exception as err: - # raise ValueError('failed to parse results XML, check URL: ' + modified_res_url) - - matches = {} - #for child in root[0]: - #if child.tag == 'hits': - # accession = child.get('acc') - # pfam_id = accession.split('.')[0] - # matches[pfam_id]={} - # matches[pfam_id]['accession']=accession - # matches[pfam_id]['class']='Domain' - # matches[pfam_id]['id']=child.get('name') - # matches[pfam_id]['locations']={} - # matches[pfam_id]['locations']['ali_end']=child[0].get('alisqto') - # matches[pfam_id]['locations']['ali_start']=child[0].get('alisqfrom') - # matches[pfam_id]['locations']['bitscore']=child[0].get('bitscore') - # matches[pfam_id]['locations']['end']=child[0].get('alisqto') - # matches[pfam_id]['locations']['evalue']=child.get('evalue') - # matches[pfam_id]['locations']['evidence']='hmmer v3.0' - # matches[pfam_id]['locations']['hmm_end']=child[0].get('alihmmto') - # matches[pfam_id]['locations']['hmm_start']=child[0].get('alihmmfrom') - # matches[pfam_id]['locations']['significant']=child[0].get('significant') - # matches[pfam_id]['locations']['start']=child[0].get('alisqfrom') - # matches[pfam_id]['type']='Pfam-A' - # return matches - - if PY3K: - tsv = tsv.decode() - - lines = tsv.split('\n') - keys = lines[0].split('\t') - root = {} - for i, line in enumerate(lines[1:-1]): - root[i] = {} - for j, key in enumerate(keys): - root[i][key] = line.split('\t')[j] - - for child in root.values(): - accession = child['Family Accession'] - pfam_id = accession.split('.')[0] - matches[pfam_id]={} - matches[pfam_id]['accession'] = accession - matches[pfam_id]['class'] = 'Domain' - matches[pfam_id]['id'] = child['Family id'] - matches[pfam_id]['locations'] = {} - matches[pfam_id]['locations']['ali_end'] = child['Ali. End'] - matches[pfam_id]['locations']['ali_start'] = child['Ali. Start'] - matches[pfam_id]['locations']['bitscore'] = child['Bit Score'] - matches[pfam_id]['locations']['end'] = child['Env. End'] - matches[pfam_id]['locations']['cond_evalue'] = child['Cond. E-value'] - matches[pfam_id]['locations']['ind_evalue'] = child['Ind. E-value'] - matches[pfam_id]['locations']['evidence'] = 'hmmer v3.0' - matches[pfam_id]['locations']['hmm_end'] = child['Model End'] - matches[pfam_id]['locations']['hmm_start'] = child['Model Start'] - #matches[pfam_id]['locations']['significant'] = child['significant'] - matches[pfam_id]['locations']['start'] = child['Env. Start'] - matches[pfam_id]['type'] = 'Pfam-A' - return matches + polymers = parsePDBHeader(seq[:4], 'polymers') + except Exception as err: + raise ValueError('failed to parse header for {0} ({1})' + .format(seq[:4], str(err))) + else: + chid = seq[4:].upper() - else: - if len(seq) <= 5: - idcode = None - from prody import parsePDBHeader - try: - polymers = parsePDBHeader(seq[:4], 'polymers') - except Exception as err: - LOGGER.warn('failed to parse header for {0} ({1})' - .format(seq[:4], str(err))) - else: - chid = seq[4:].upper() - - for poly in polymers: - if chid and poly.chid != chid: + for poly in polymers: + if chid and poly.chid != chid: + continue + for dbref in poly.dbrefs: + if dbref.database != 'UniProt': continue - for dbref in poly.dbrefs: - if dbref.database != 'UniProt': - continue - idcode = dbref.idcode - accession = dbref.accession - LOGGER.info('UniProt ID code {0} for {1} chain ' - '{2} will be used.' - .format(idcode, seq[:4], poly.chid)) - break - if idcode is not None: - break - if idcode is None: - LOGGER.warn('A UniProt ID code for PDB {0} could not be ' - 'parsed.'.format(repr(seq))) - url = prefix + 'protein/' + seq + '?output=xml' - else: - url = prefix + 'protein/' + idcode + '?output=xml' - + accession = dbref.accession + LOGGER.info('UniProt accession {0} for {1} chain ' + '{2} will be used.' + .format(accession, seq[:4], poly.chid)) + break + if accession is not None: + break + if accession is None: + raise ValueError('A UniProt accession for PDB {0} could not be ' + 'parsed.'.format(repr(seq))) else: - url = prefix + 'protein/' + seq + '?output=xml' + url = prefix + "all/protein/uniprot/" + accession + + else: + url = prefix + "all/protein/uniprot/" + seq LOGGER.debug('Retrieving Pfam search results: ' + url) xml = None sleep = 2 while LOGGER.timing('_pfam') < timeout: try: - # xml = openURL(url, timeout=timeout).read() xml = requests.get(url, verify=False).content except Exception: pass @@ -227,78 +120,47 @@ def searchPfam(query, **kwargs): if PY3K: xml = xml.decode() + else: + xml = xml.encode() if xml.find('There was a system error on your last request.') > 0: LOGGER.warn('No Pfam matches found for: ' + seq) return None elif xml.find('No valid UniProt accession or ID') > 0: - try: - url = prefix + 'protein/' + accession + '?output=xml' - LOGGER.debug('Retrieving Pfam search results: ' + url) - xml = openURL(url, timeout=timeout).read() - except: - raise ValueError('No valid UniProt accession or ID for: ' + seq) - - if xml.find('No valid UniProt accession or ID') > 0: - try: - ag = parsePDB(seq, subset='ca') - ag_seq = ag.getSequence() - return searchPfam(ag_seq) - except: - try: - url = 'https://uniprot.org/uniprot/' + accession + '.xml' - xml = openURL(url, timeout=timeout).read() - if len(xml) > 0: - root = ET.XML(xml) - accession = root[0][0].text - - url = prefix + 'protein/' + accession + '?output=xml' - LOGGER.debug('Retrieving Pfam search results: ' + url) - xml = openURL(url, timeout=timeout).read() - else: - raise ValueError('No valid UniProt accession or ID for: ' + seq) - except: - raise ValueError('No valid UniProt accession or ID for: ' + seq) + raise ValueError('No valid UniProt accession or ID for: ' + seq) try: - root = ET.XML(xml) + root = json.loads(xml) except Exception as err: raise ValueError('failed to parse results XML, check URL: ' + url) - if len(seq) >= MINSEQLEN: - try: - xml_matches = root[0][0][0][0] - except IndexError: - raise ValueError('failed to parse results XML, check URL: ' + url) - else: - key = '{' + old_prefix + '}' - results = dictElement(root[0], key) - try: - xml_matches = results['matches'] - except KeyError: - raise ValueError('failed to parse results XML, check URL: ' + url) - matches = dict() - for child in xml_matches: - + for entry in root["results"]: try: - accession = child.attrib['accession'][:7] + metadata = entry["metadata"] + accession = metadata["accession"] except KeyError: - raise ValueError('failed to parse results XML, check URL: ' + url) + raise ValueError('failed to parse accessions from results, check URL: ' + url) - if not re.search('^P(F|B)[0-9]{5}$', accession): - raise ValueError('{0} does not match pfam accession' - ' format'.format(accession)) - - match = matches.setdefault(accession, dict(child.items())) - locations = match.setdefault('locations', []) - for loc in child: - locations.append(dict(loc.items())) + if not re.search('PF[0-9]{5}$', accession): + continue - if len(seq) < MINSEQLEN: - query = 'Query ' + repr(query) - else: - query = 'Query sequence' + match = matches.setdefault(accession, dict(metadata.items())) + + other_data = entry["proteins"] + locations = match.setdefault("locations", []) + for item1 in other_data: + for key, value in item1.items(): + if key == "entry_protein_locations": + for item2 in value: + new_dict = {} + for item3 in value[0]["fragments"]: + new_dict["start"] = item3["start"] + new_dict["end"] = item3["end"] + new_dict["score"] = item2["score"] + locations.append(new_dict) + + query = 'Query ' + repr(query) if matches: LOGGER.info(query + ' matched {0} Pfam families.'.format(len(matches))) @@ -320,21 +182,6 @@ def fetchPfamMSA(acc, alignment='full', compressed=False, **kwargs): :arg compressed: gzip the downloaded MSA file, default is **False** - *Alignment Options* - - :arg format: a Pfam supported MSA file format, one of ``'selex'``, - (default), ``'stockholm'`` or ``'fasta'`` - - :arg order: ordering of sequences, ``'tree'`` (default) or - ``'alphabetical'`` - - :arg inserts: letter case for inserts, ``'upper'`` (default) or ``'lower'`` - - :arg gaps: gap character, one of ``'dashes'`` (default), ``'dots'``, - ``'mixed'`` or **None** for unaligned - - *Other Options* - :arg timeout: timeout for blocking connection attempt in seconds, default is 60 @@ -344,69 +191,21 @@ def fetchPfamMSA(acc, alignment='full', compressed=False, **kwargs): import requests - # url = prefix + 'family/acc?id=' + acc - # handle = openURL(url, timeout=int(kwargs.get('timeout', 60))) - orig_acc = acc - # acc = handle.readline().strip() - # if PY3K: - # acc = acc.decode() - url_flag = False - if not re.search('(?<=PF)[0-9]{5}$', acc): raise ValueError('{0} is not a valid Pfam ID or Accession Code' - .format(repr(orig_acc))) + .format(repr(acc))) if alignment not in DOWNLOAD_FORMATS: - raise ValueError('alignment must be one of full, seed, ncbi or' - ' metagenomics') - if alignment == 'ncbi' or alignment == 'metagenomics' or alignment == 'uniprot': - url = (prefix + 'family/' + acc + '/alignment/' + - alignment + '/gzipped') - url_flag = True - extension = '.sth' - else: - if not kwargs: - url = (prefix + 'family/' + acc + '/alignment/' + - alignment + '/gzipped') - url_flag = True - extension = '.sth' - else: - align_format = kwargs.get('format', 'selex').lower() - - if align_format not in FORMAT_OPTIONS['format']: - raise ValueError('alignment format must be of type selex' - ' stockholm or fasta. MSF not supported') - - if align_format == SELEX: - align_format, extension = 'pfam', '.slx' - elif align_format == FASTA: - extension = '.fasta' - else: - extension = '.sth' - - gaps = str(kwargs.get('gaps', 'dashes')).lower() - if gaps not in FORMAT_OPTIONS['gaps']: - raise ValueError('gaps must be of type mixed, dots, dashes, ' - 'or None') + raise ValueError('alignment must be one of full, seed, or uniprot') - inserts = kwargs.get('inserts', 'upper').lower() - if(inserts not in FORMAT_OPTIONS['inserts']): - raise ValueError('inserts must be of type lower or upper') - - order = kwargs.get('order', 'tree').lower() - if order not in FORMAT_OPTIONS['order']: - raise ValueError('order must be of type tree or alphabetical') - - url = (prefix + 'family/' + acc + '/alignment/' - + alignment + '/format?format=' + align_format + - '&alnType=' + alignment + '&order=' + order[0] + - '&case=' + inserts[0] + '&gaps=' + gaps + '&download=1') + url = (prefix + "/pfam/" + acc + + '/?annotation=alignment:' + alignment + '&download') + extension = '.sth' LOGGER.timeit('_pfam') timeout = kwargs.get('timeout', 60) response = None sleep = 2 - try_error = 3 while LOGGER.timing('_pfam') < timeout: try: response = requests.get(url, verify=False).content @@ -418,32 +217,22 @@ def fetchPfamMSA(acc, alignment='full', compressed=False, **kwargs): sleep = 20 if int(sleep * 1.5) >= 20 else int(sleep * 1.5) LOGGER.sleep(int(sleep), '. Trying to reconnect...') - # response = openURL(url, timeout=int(kwargs.get('timeout', 60))) outname = kwargs.get('outname', None) if not outname: - outname = orig_acc + outname = acc folder = str(kwargs.get('folder', '.')) filepath = join(makePath(folder), outname + '_' + alignment + extension) if compressed: filepath = filepath + '.gz' - if url_flag: - f_out = open(filepath, 'wb') - else: - f_out = openFile(filepath, 'wb') - # f_out.write(response.read()) + f_out = open(filepath, 'wb') f_out.write(response) f_out.close() else: - if url_flag: - gunzip(response, filepath) - else: - with open(filepath, 'wb') as f_out: - # f_out.write(response.read()) - f_out.write(response) + gunzip(response, filepath) filepath = relpath(filepath) LOGGER.info('Pfam MSA for {0} is written as {1}.' - .format(orig_acc, filepath)) + .format(acc, filepath)) return filepath @@ -471,6 +260,8 @@ def parsePfamPDBs(query, data=[], **kwargs): The PFAM domain that ends closest to this will be selected. :type end: int """ + + only_parse = kwargs.pop('only_parse', False) start = kwargs.pop('start', 1) end = kwargs.pop('end', None) @@ -478,6 +269,10 @@ def parsePfamPDBs(query, data=[], **kwargs): if len(query) > 4 and query.startswith('PF'): pfam_acc = query else: + if not isinstance(start, Integral) and not isinstance(end, Integral): + raise ValueError('Please provide an integer for start or end ' + 'when using a UniProt ID or PDB ID.') + pfam_matches = searchPfam(query, **kwargs) keys = list(pfam_matches.keys()) @@ -495,17 +290,13 @@ def parsePfamPDBs(query, data=[], **kwargs): start_diff = np.array(start_diff) pfam_acc = keys[np.where(abs(start_diff) == min(abs(start_diff)))[0][0]] - elif isinstance(end, Integral): + if isinstance(end, Integral): end_diff = [] for i, key in enumerate(pfam_matches): end_diff.append(int(pfam_matches[key]['locations'][0]['end']) - end) end_diff = np.array(end_diff) pfam_acc = keys[np.where(abs(end_diff) == min(abs(end_diff)))[0][0]] - else: - raise ValueError('Please provide an integer for start or end ' - 'when using a UniProt ID or PDB ID.') - from ftplib import FTP from .uniprot import queryUniprot @@ -552,10 +343,16 @@ def parsePfamPDBs(query, data=[], **kwargs): else: results = ags + if only_parse: + return [result for result in results if result is not None] + LOGGER.progress('Extracting Pfam domains...', len(ags)) comma_splitter = re.compile(r'\s*,\s*').split no_info = [] for i, ag in enumerate(ags): + if ag is None: + continue + LOGGER.update(i) data_dict = data_dicts[i] pfamRange = data_dict['UniprotResnumRange'].split('-') @@ -575,7 +372,7 @@ def parsePfamPDBs(query, data=[], **kwargs): pdbid = value['PDB'] except: continue - if pdbid != data_dict['PDB_ID']: + if pdbid.lower() != data_dict['PDB_ID'].lower(): continue pdbchains = value['chains'] @@ -635,5 +432,5 @@ def parsePfamPDBs(query, data=[], **kwargs): else: LOGGER.warn('data should be a list in order to get output') - return results + return [result for result in results if result is not None] diff --git a/prody/measure/contacts.py b/prody/measure/contacts.py index 93471fc6c..eb400e020 100644 --- a/prody/measure/contacts.py +++ b/prody/measure/contacts.py @@ -5,7 +5,7 @@ from prody.atomic import Atomic, Atom, AtomGroup, AtomSubset, Selection from prody.kdtree import KDTree -from prody.utilities import rangeString +from prody.utilities import rangeString, LOGGER __all__ = ['Contacts', 'iterNeighbors', 'findNeighbors'] @@ -131,16 +131,23 @@ def getUnitcell(self): return self._unitcell.copy() -def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): +def iterNeighbors(atoms, radius, atoms2=None, unitcell=None, seqsep=None): """Yield pairs of *atoms* that are within *radius* of each other and the - distance between them. If *atoms2* is also provided, one atom from *atoms* + distance between them. + + If *atoms2* is also provided, one atom from *atoms* and another from *atoms2* will be yielded. If one of *atoms* or *atoms2* is a coordinate array, pairs of indices and distances will be yielded. + When orthorhombic *unitcell* dimensions are provided, periodic boundary conditions will be taken into account (see :class:`.KDTree` and also :func:`wrapAtoms` for details). If *atoms* is a :class:`.Frame` instance and *unitcell* is not provided, unitcell information from frame will be - if available.""" + used if available. + + If *seqsep* is provided, neighbors will be kept if the sequence separation >= *seqsep*. + Note that *seqsep* will be ignored if atoms are not provided. + """ radius = float(radius) if radius <= 0: @@ -190,6 +197,9 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): if coords.ndim == 1: coords = array([coords]) + warned = False + SEQDIST_COORDS_WARNING = 'seqsep is ignored when not using Atomic objects' + if atoms2 is None: if len(coords) <= 1: raise ValueError('atoms must be more than 1') @@ -199,6 +209,9 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): _dict = {} if ag is None: for (i, j), r in zip(*kdtree(radius)): + if seqsep is not None and not warned: + LOGGER.warn(SEQDIST_COORDS_WARNING) + warned = True yield (i, j, r) else: for (i, j), r in zip(*kdtree(radius)): @@ -210,7 +223,8 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): if a2 is None: a2 = Atom(ag, index(j), acsi) _dict[j] = a2 - yield (a1, a2, r) + if seqsep is None or abs(a1.getResnum() - a2.getResnum()) >= seqsep: + yield (a1, a2, r) else: try: coords2 = atoms2._getCoords() @@ -251,6 +265,9 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): if ag is None or ag2 is None: for j, xyz in enumerate(coords2): for i, r in zip(*kdtree(radius, xyz)): + if seqsep is not None and not warned: + LOGGER.warn(SEQDIST_COORDS_WARNING) + warned = True yield (i, j, r) else: for a2 in atoms2.iterAtoms(): @@ -259,13 +276,17 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): if a1 is None: a1 = Atom(ag, index(i), acsi) _dict[i] = a1 - yield (a1, a2, r) + if seqsep is None or abs(a1.getResnum() - a2.getResnum()) < seqsep: + yield (a1, a2, r) else: kdtree = KDTree(coords2, unitcell=unitcell, none=list) _dict = {} if ag is None or ag2 is None: for i, xyz in enumerate(coords): for j, r in zip(*kdtree(radius, xyz)): + if seqsep is not None and not warned: + LOGGER.warn(SEQDIST_COORDS_WARNING) + warned = True yield (i, j, r) else: for a1 in atoms.iterAtoms(): @@ -274,11 +295,12 @@ def iterNeighbors(atoms, radius, atoms2=None, unitcell=None): if a2 is None: a2 = Atom(ag2, index2(i), acsi2) _dict[i] = a2 - yield (a1, a2, r) + if seqsep is None or abs(a1.getResnum() - a2.getResnum()) < seqsep: + yield (a1, a2, r) -def findNeighbors(atoms, radius, atoms2=None, unitcell=None): +def findNeighbors(atoms, radius, atoms2=None, unitcell=None, seqsep=None): """Returns list of neighbors that are within *radius* of each other and the distance between them. See :func:`iterNeighbors` for more details.""" - return list(iterNeighbors(atoms, radius, atoms2, unitcell)) + return list(iterNeighbors(atoms, radius, atoms2, unitcell, seqsep)) diff --git a/prody/measure/measure.py b/prody/measure/measure.py index 2f79ba1e8..9ad532d73 100644 --- a/prody/measure/measure.py +++ b/prody/measure/measure.py @@ -31,7 +31,7 @@ DISTMAT_FORMATS = set(['mat', 'rcd', 'arr']) -def buildDistMatrix(atoms1, atoms2=None, unitcell=None, format='mat'): +def buildDistMatrix(atoms1, atoms2=None, unitcell=None, format='mat', seqsep=None): """Returns distance matrix. When *atoms2* is given, a distance matrix with shape ``(len(atoms1), len(atoms2))`` is built. When *atoms2* is **None**, a symmetric matrix with shape ``(len(atoms1), len(atoms1))`` @@ -50,7 +50,16 @@ def buildDistMatrix(atoms1, atoms2=None, unitcell=None, format='mat'): :arg format: format of the resulting array, one of ``'mat'`` (matrix, default), ``'rcd'`` (arrays of row indices, column indices, and distances), or ``'arr'`` (only array of distances) - :type format: bool""" + :type format: bool + + :arg seqsep: if provided, distances will only be measured between atoms + with resnum differences that are greater than or equal to seqsep. + :type seqsep: int + """ + + spacing = 1 + if seqsep is not None: + spacing = seqsep - 1 if not isinstance(atoms1, ndarray): try: @@ -86,10 +95,10 @@ def buildDistMatrix(atoms1, atoms2=None, unitcell=None, format='mat'): raise ValueError('format must be one of mat, rcd, or arr') if format == 'mat': for i, xyz in enumerate(atoms1[:-1]): - dist[i, i+1:] = dist[i+1:, i] = getDistance(xyz, atoms2[i+1:], + dist[i, i+spacing:] = dist[i+spacing:, i] = getDistance(xyz, atoms2[i+spacing:], unitcell) else: - dist = concatenate([getDistance(xyz, atoms2[i+1:], unitcell) + dist = concatenate([getDistance(xyz, atoms2[i+spacing:], unitcell) for i, xyz in enumerate(atoms1)]) if format == 'rcd': n_atoms = len(atoms1) @@ -720,7 +729,7 @@ def calcADPAxes(atoms, **kwargs): # Make sure the direction that correlates with the previous atom # is selected vals = vals * sign((vecs * axes[(i-1)*3:(i)*3, :]).sum(0)) - axes[i*3:(i+1)*3, :] = vals * vecs + axes[i*3:(i+spacing)*3, :] = vals * vecs # Resort the columns before returning array axes = axes[:, [2, 1, 0]] torf = None @@ -802,7 +811,7 @@ def buildADPMatrix(atoms): element[0, 1] = element[1, 0] = anisou[3] element[0, 2] = element[2, 0] = anisou[4] element[1, 2] = element[2, 1] = anisou[5] - adp[i*3:(i+1)*3, i*3:(i+1)*3] = element + adp[i*3:(i+spacing)*3, i*3:(i+spacing)*3] = element return adp @@ -860,7 +869,7 @@ def calcDistanceMatrix(coords, cutoff=None): r += 1 for i in range(n_atoms): - for j in range(i+1, n_atoms): + for j in range(i+spacing, n_atoms): if dist_mat[i, j] == 0.: dist_mat[i, j] = dist_mat[j, i] = max(dists) @@ -1015,7 +1024,7 @@ def assignBlocks(atoms, res_per_block=None, secstr=False, **kwargs): block = where(blocks == i)[0] if len(block) < shortest_block: block_im1 = where(blocks == i-1)[0] - block_ip1 = where(blocks == i+1)[0] + block_ip1 = where(blocks == i+spacing)[0] dist_back = calcDistance(atoms[block_im1][-1], atoms[block][0]) dist_fwd = calcDistance(atoms[block][-1], atoms[block_ip1][0]) @@ -1025,7 +1034,7 @@ def assignBlocks(atoms, res_per_block=None, secstr=False, **kwargs): blocks[where(blocks == i)[0]] = i-1 elif dist_fwd < min_dist_cutoff: # join onto next block - blocks[where(blocks == i)[0]] = i+1 + blocks[where(blocks == i)[0]] = i+spacing blocks, amap = extendAtomicData(blocks, sel_ca, atoms) diff --git a/prody/proteins/ciffile.py b/prody/proteins/ciffile.py index 4d66dbb8a..921736ac0 100644 --- a/prody/proteins/ciffile.py +++ b/prody/proteins/ciffile.py @@ -512,7 +512,7 @@ def _parseMMCIFLines(atomgroup, lines, model, chain, subset, LOGGER.warn("No anisotropic B factors found") else: anisou = np.zeros((acount, 6), - dtype=ATOMIC_FIELDS['anisou'].dtype) + dtype=float) if "_atom_site_anisotrop.U[1][1]_esd" in data[0].keys(): siguij = np.zeros((acount, 6), diff --git a/prody/proteins/interactions.py b/prody/proteins/interactions.py index f3712d94e..a87db9e19 100644 --- a/prody/proteins/interactions.py +++ b/prody/proteins/interactions.py @@ -44,7 +44,8 @@ 'calcLigandInteractions', 'listLigandInteractions', 'showProteinInteractions_VMD', 'showLigandInteraction_VMD', 'calcHydrogenBondsTrajectory', 'calcHydrophobicOverlapingAreas', - 'Interactions', 'InteractionsTrajectory', 'LigandInteractionsTrajectory'] + 'Interactions', 'InteractionsTrajectory', 'LigandInteractionsTrajectory', + 'calcSminaBindingAffinity'] def cleanNumbers(listContacts): @@ -281,6 +282,7 @@ def calcSASA(atoms, **kwargs): else: return [ float(i[-1]) for i in output_final ] + def calcVolume(atoms, **kwargs): """Provide information about volume for each residue/molecule/chain or other selection". To use this function compiled hpb.so is needed. @@ -2014,17 +2016,24 @@ def calcDistribution(interactions, residue1, residue2=None, **kwargs): LOGGER.info(i) -def listLigandInteractions(PLIP_output): +def listLigandInteractions(PLIP_output, **kwargs): """Create a list of interactions from PLIP output created using calcLigandInteractions(). Results can be displayed in VMD. :arg PLIP_output: Results from PLIP for protein-ligand interactions. - :type PLIP_output: PLIP object obtained from calcLigandInteractions() + :type PLIP_output: PLIP object obtained from calcLigandInteractions() + + :arg output: parameter to print the interactions on the screen + while analyzing the structure (True | False) + by default is False + :type output: bool Note that five types of interactions are considered: hydrogen bonds, salt bridges, pi-stacking, cation-pi, hydrophobic and water bridges.""" Inter_list_all = [] + output = kwargs.pop('output', False) + for i in PLIP_output.all_itypes: param_inter = [method for method in dir(i) if method.startswith('_') is False] @@ -2062,13 +2071,14 @@ def listLigandInteractions(PLIP_output): Inter_list_all.append(Inter_list) - LOGGER.info("%3s%12s%10s%20s%8s <---> %6s%10s%6s%10s%16s" % ('#','Type','Residue','Atoms','Chain','','Ligand','Atoms','Chain','Distance/Angle')) - for nr_k,k in enumerate(Inter_list_all): - if k[0] == 'watBridge': - LOGGER.info("%3i%12s%10s%26s%4s <---> %8s%12s%4s%12s%14s" % (nr_k+1,k[0],k[1],k[2],k[3],k[4],k[5],k[6], - ' '.join(str(np.round(x, 2)) for x in k[7]), ' '.join(str(np.round(x, 2)) for x in k[8]))) - else: - LOGGER.info("%3i%12s%10s%26s%4s <---> %8s%12s%4s%6.1f" % (nr_k+1,k[0],k[1],k[2],k[3],k[4],k[5],k[6],k[7])) + if output == True: + LOGGER.info("%3s%12s%10s%20s%8s <---> %6s%10s%6s%10s%16s" % ('#','Type','Residue','Atoms','Chain','','Ligand','Atoms','Chain','Distance/Angle')) + for nr_k,k in enumerate(Inter_list_all): + if k[0] == 'watBridge': + LOGGER.info("%3i%12s%10s%26s%4s <---> %8s%12s%4s%12s%14s" % (nr_k+1,k[0],k[1],k[2],k[3],k[4],k[5],k[6], + ' '.join(str(np.round(x, 2)) for x in k[7]), ' '.join(str(np.round(x, 2)) for x in k[8]))) + else: + LOGGER.info("%3i%12s%10s%26s%4s <---> %8s%12s%4s%6.1f" % (nr_k+1,k[0],k[1],k[2],k[3],k[4],k[5],k[6],k[7])) return Inter_list_all @@ -2122,7 +2132,7 @@ def calcLigandInteractions(atoms, **kwargs): import tempfile with tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file: - writePDB(temp_pdb_file.name, atoms) + writePDB(temp_pdb_file.name, atoms, csets=atoms.getACSIndex()) temp_pdb_file_name = temp_pdb_file.name try: @@ -2169,7 +2179,6 @@ def calcLigandInteractions(atoms, **kwargs): LOGGER.info("Ligand not found.") - def showProteinInteractions_VMD(atoms, interactions, color='red',**kwargs): """Save information about protein interactions to a TCL file (filename) which can be further use in VMD to display all intercations in a graphical interface @@ -2223,7 +2232,7 @@ def TCLforSingleInteraction(interaction, color='blue', tcl_file=tcl_file): computed by any function which returns interactions. :arg interactions: List of interaction lists for protein interactions. - :type interactions: List + :type interactions: list :arg color: Name of the color which will be used for the visualization of interactions in VMD @@ -2349,6 +2358,181 @@ def showLigandInteraction_VMD(atoms, interactions, **kwargs): LOGGER.info("TCL file saved") +def calcSminaBindingAffinity(atoms, trajectory=None, **kwargs): + """Computing binding affinity of ligand toward protein structure + usig SMINA package [DRK13]_. + + :arg atoms: an Atomic object from which residues are selected + :type atoms: :class:`.Atomic`, :class:`.LigandInteractionsTrajectory` + + :arg protein_selection: selection string for the protein and other compoment + of the system that should be included, + e.g. "protein and chain A", + by default "protein" + :type protein_selection: str + + :arg ligand_selection: selection string for ligand, + e.g. "resname ADP", + by default "all not protein" + :type ligand_selection: str + + :arg ligand_selection: scoring function (vina or vinardo) + by default is "vina" + + :type ligand_selection: str + + SMINA installation is required to compute ligand binding affinity: + >> conda install -c conda-forge smina (for Anaconda) + + For more information on SMINA see https://sourceforge.net/projects/smina/. + If you benefited from SMINA, please consider citing [DRK13]_. + + .. [DRK13] Koes D. R., Baumgartner M. P., Camacho C. J., Lessons Learned in + Empirical Scoring with smina from the CSAR 2011 Benchmarking Exercise, + *J. Chem. Inf. Model.* **2013** 53: 1893–1904. """ + + import tempfile + import subprocess + import re + + if isinstance(atoms, LigandInteractionsTrajectory): + atoms = atoms._atoms + trajectory = atoms._traj + + try: + coords = (atoms._getCoords() if hasattr(atoms, '_getCoords') else + atoms.getCoords()) + except AttributeError: + try: + checkCoords(coords) + except TypeError: + raise TypeError('coords must be an object ' + 'with `getCoords` method') + + start_frame = kwargs.pop('start_frame', 0) + stop_frame = kwargs.pop('stop_frame', -1) + protein_selection = kwargs.pop('protein_selection', "protein") + ligand_selection = kwargs.pop('ligand_selection', "all not protein") + scoring_function = kwargs.pop('scoring_function', 'vina') + bindingAffinity = [] + + if trajectory is not None: + # Trajectory + if isinstance(trajectory, Atomic): + trajectory = Ensemble(trajectory) + + nfi = trajectory._nfi + trajectory.reset() + numFrames = trajectory._n_csets + + if stop_frame == -1: + traj = trajectory[start_frame:] + else: + traj = trajectory[start_frame:stop_frame+1] + + atoms_copy = atoms.copy() + + for j0, frame0 in enumerate(traj, start=start_frame): + atoms_copy.setCoords(frame0.getCoords()) + protein = atoms_copy.select(protein_selection) + ligand = atoms_copy.select(ligand_selection) + + with tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file, \ + tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file_lig: + + # Files are starage in the memory + writePDB(temp_pdb_file.name, protein) + writePDB(temp_pdb_file_lig.name, ligand) + + data = {} + command = "smina -r {} -l {} --score_only --scoring {}".format(temp_pdb_file.name, temp_pdb_file_lig.name, scoring_function) + result = subprocess.check_output(command, shell=True, text=True) + + result = re.sub(r".*Affinity:", "Affinity:", result, flags=re.DOTALL) + + matches = re.finditer(r'(?P[\w\s]+):\s+([0-9.-]+)\s+\(kcal/mol\)', result) + for match in matches: + key = match.group('key') + value = float(match.group(2)) + data[key] = value + + intramolecular_energy_match = re.search(r'Intramolecular energy: ([0-9.-]+)', result) + if intramolecular_energy_match: + data['Intramolecular energy'] = float(intramolecular_energy_match.group(1)) + + LOGGER.info('Frame {0}: {1} kcal/mol'.format(j0, data['Affinity'])) + bindingAffinity.append(data['Affinity']) + + trajectory._nfi = nfi + + else: + if atoms.numCoordsets() == 1: + # Single PDB + protein = atoms.select(protein_selection) + ligand = atoms.select(ligand_selection) + + with tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file, \ + tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file_lig: + + writePDB(temp_pdb_file.name, protein) + writePDB(temp_pdb_file_lig.name, ligand) + + data = {} + command = "smina -r {} -l {} --score_only --scoring {}".format(temp_pdb_file.name, temp_pdb_file_lig.name, scoring_function) + result = subprocess.check_output(command, shell=True, text=True) + + result = re.sub(r".*Affinity:", "Affinity:", result, flags=re.DOTALL) + + matches = re.finditer(r'(?P[\w\s]+):\s+([0-9.-]+)\s+\(kcal/mol\)', result) + for match in matches: + key = match.group('key') + value = float(match.group(2)) + data[key] = value + + intramolecular_energy_match = re.search(r'Intramolecular energy: ([0-9.-]+)', result) + if intramolecular_energy_match: + data['Intramolecular energy'] = float(intramolecular_energy_match.group(1)) + + bindingAffinity.append(data['Affinity']) + + if atoms.numCoordsets() > 1: + # Multi-model PDB + for i in range(len(atoms.getCoordsets()[start_frame:stop_frame])): + atoms.setACSIndex(i+start_frame) + protein = atoms.select(protein_selection) + ligand = atoms.select(ligand_selection) + + with tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file, \ + tempfile.NamedTemporaryFile(delete=False, suffix=".pdb") as temp_pdb_file_lig: + + writePDB(temp_pdb_file.name, protein, csets=atoms.getACSIndex()) + writePDB(temp_pdb_file_lig.name, ligand, csets=atoms.getACSIndex()) + + data = {} + command = "smina -r {} -l {} --score_only --scoring {}".format(temp_pdb_file.name, temp_pdb_file_lig.name, scoring_function) + result = subprocess.check_output(command, shell=True, text=True) + + result = re.sub(r".*Affinity:", "Affinity:", result, flags=re.DOTALL) + + matches = re.finditer(r'(?P[\w\s]+):\s+([0-9.-]+)\s+\(kcal/mol\)', result) + for match in matches: + key = match.group('key') + value = float(match.group(2)) + data[key] = value + + intramolecular_energy_match = re.search(r'Intramolecular energy: ([0-9.-]+)', result) + if intramolecular_energy_match: + data['Intramolecular energy'] = float(intramolecular_energy_match.group(1)) + + LOGGER.info('Model {0}: {1} kcal/mol'.format(i+start_frame, data['Affinity'])) + bindingAffinity.append(data['Affinity']) + + else: + LOGGER.info('Include trajectory or use multi-model PDB file.') + + return bindingAffinity + + class Interactions(object): """Class for Interaction analysis of proteins.""" @@ -2834,8 +3018,9 @@ def getFrequentInteractors(self, contacts_min=3): (6) Hydrophobic interactions (hp) (7) Disulfide bonds (disb) - :arg contacts_min: Minimal number of contacts which residue may form with other residues. - :type contacts_min: int, be default 3. """ + :arg contacts_min: Minimal number of contacts which residue may form with other residues, + by default 3. + :type contacts_min: int """ atoms = self._atoms interactions = self._interactions @@ -3631,7 +3816,6 @@ def getTimeInteractions(self, filename=None, **kwargs): class LigandInteractionsTrajectory(object): - """Class for protein-ligand interaction analysis of DCD trajectory or multi-model PDB (Ensemble PDB). This class is using PLIP to provide the interactions. Install PLIP before using it. @@ -3652,8 +3836,10 @@ def __init__(self, name='Unknown'): self._atoms = None self._traj = None self._interactions_traj = None + self._freq_interactors = None - def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None, **kwargs): + + def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, **kwargs): """Compute protein-ligand interactions for DCD trajectory or multi-model PDB using PLIP library. @@ -3670,7 +3856,13 @@ def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None :type start_frame: int :arg stop_frame: index of last frame to read - :type stop_frame: int """ + :type stop_frame: int + + :arg output: parameter to print the interactions on the screen + while analyzing the structure, + use 'info'. + :type output: bool + """ try: coords = (atoms._getCoords() if hasattr(atoms, '_getCoords') else @@ -3687,6 +3879,8 @@ def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None start_frame = kwargs.pop('start_frame', 0) stop_frame = kwargs.pop('stop_frame', -1) + output = kwargs.pop('output', False) + filename = kwargs.pop('filename', None) if trajectory is not None: if isinstance(trajectory, Atomic): @@ -3712,7 +3906,7 @@ def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None ligs_per_frame_interactions = [] for ligs in ligand_interactions: - LP_interactions = listLigandInteractions(ligs) + LP_interactions = listLigandInteractions(ligs, output=output) ligs_per_frame_interactions.extend(LP_interactions) interactions_all.append(ligs_per_frame_interactions) @@ -3729,7 +3923,7 @@ def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None ligs_per_frame_interactions = [] for ligs in ligand_interactions: - LP_interactions = listLigandInteractions(ligs) + LP_interactions = listLigandInteractions(ligs, output=output) ligs_per_frame_interactions.extend(LP_interactions) interactions_all.append(ligs_per_frame_interactions) @@ -3751,23 +3945,94 @@ def calcLigandInteractionsTrajectory(self, atoms, trajectory=None, filename=None return interactions_all - + def getLigandInteractions(self, **kwargs): - """Return the list of protein-ligand interactions.""" - - return self._interactions_traj - + """Return the list of protein-ligand interactions. + + :arg filters: selection string of ligand with chain ID or interaction type + e.g. 'SBs' (HBs, SBs, HPh, PiStack, PiCat, HPh, watBridge) + :type filters: str + + :arg include_frames: used with filters, it will leave selected keyword in orginal + lists, if False it will collect selected interactions in one list, + Use True to assign new selection using setLigandInteractions. + by default True + :type include_frames: bool + """ + + filters = kwargs.pop('filters', None) + include_frames = kwargs.pop('include_frames', True) + filtered_lists = [] + + if filters != None: + if include_frames == False: + filtered_lists = [element for group in self._interactions_traj for element in group + if filters in element] + if include_frames == True: + filtered_lists = [] + for i in self._interactions_traj: + filtered_lists.append([item for item in i if filters in item]) + + return filtered_lists + + else: + return self._interactions_traj + def getAtoms(self): """Returns associated atoms.""" return self._atoms + + def setLigandInteractions(self, atoms, interaction): + """Replace protein-ligand interactions + for example byb using getLigandInteractions() with filters to select particular ligand. + + :arg atoms: an Atomic object from which residues are selected + :type atoms: :class:`.Atomic` + + :arg interactions: list of interactions + :type interactions: list + """ + + self._interactions_traj = interaction + self._atoms = atoms + LOGGER.info('Protein-ligand interactions are replaced.') - def getLigandInteractionsNumber(self): - """Return the number of interactions in each frame.""" + + def getLigandInteractionsNumber(self, **kwargs): + """Return the number of interactions per each frame. Number of interactions can + be a total number of interactions or it can be divided into interaction types. - return self._interactions_nb_traj + :arg types: Interaction types can be included (True) or not (False). + by default is True. + :type types: bool + """ + + types = kwargs.pop('types', True) + + if types == True: + interactions = self._interactions_traj + unique_keywords = set() + + for sublist in interactions: + for sublist_item in sublist: + keyword = sublist_item[0] + unique_keywords.add(keyword) + unique_keywords_list = list(unique_keywords) + + keyword_counts = {keyword: [0] * len(interactions) for keyword in unique_keywords_list} + + for i, sublist in enumerate(interactions): + for sublist_item in sublist: + keyword = sublist_item[0] + keyword_counts[keyword][i] += 1 + + return keyword_counts + + else: + return self._interactions_nb_traj def parseLigandInteractions(self, filename): @@ -3786,3 +4051,156 @@ def parseLigandInteractions(self, filename): return data + + def getInteractionTypes(self): + """Show which interaction types were detected for ligands.""" + + interactions = self._interactions_traj + unique_keywords = set() + + for sublist in interactions: + for sublist_item in sublist: + keyword = sublist_item[0] + unique_keywords.add(keyword) + + unique_keywords_list = list(unique_keywords) + LOGGER.info("Interaction types: {0}".format(unique_keywords_list)) + + return unique_keywords_list + + + def getLigandsNames(self): + """Show which ligands are in a system.""" + + interactions = self._interactions_traj + ligands = set() + + for sublist in interactions: + for sublist_item in sublist: + keyword = sublist_item[4] + ligands.add(keyword) + + ligands_list = list(ligands) + + return ligands_list + + + def calcFrequentInteractors(self, **kwargs): + """Returns a dictonary with residues involved in the interaction with ligand + and their number of counts. + + :arg selection: selection string of ligand with chain ID + e.g. "MESA" where MES is ligand resname and A is chain ID. + Selection pointed as None will return all interactions together + without ligands separation. + :type selection: str + + :arg contacts_min: Minimal number of contacts which residue may form with ligand. + by default is 2. + :type contacts_min: int """ + + atoms = self._atoms + interactions = self._interactions_traj + contacts_min = kwargs.pop('contacts_min', 2) + selection = kwargs.pop('selection', None) + + from collections import Counter + + if selection == None: # Compute all interactions without distinguishing ligands + all_residues = [ j[1]+j[3] for i in interactions for j in i ] + dictOfInteractions = Counter(all_residues) + + else: + interactions2 = [element for group in interactions for element in group] + ligs = {} + dictOfInteractions = [] + for i in interactions2: + ligs_names = i[4]+i[6] + if ligs_names not in ligs: + ligs[ligs_names] = [] + + res_name = i[1]+i[3] + ligs[ligs_names].append(res_name) + + for i in ligs.keys(): + + if selection == None: + LOGGER.info('LIGAND: {0}'.format(i)) + aa_counter = Counter(ligs[i]) + dictOfInteractions.append(aa_counter) + + else: + if selection not in ligs.keys(): + LOGGER.info('Wrong selection. Please provide ligand name with chain ID.') + if i == selection: + LOGGER.info('LIGAND: {0}'.format(selection)) + aa_counter = Counter(ligs[selection]) + dictOfInteractions.append(aa_counter) + + self._freq_interactors = dictOfInteractions + + return dictOfInteractions + + + def saveInteractionsPDB(self, **kwargs): + """Save the number of interactions with ligand to PDB file in occupancy column + It will recognize the chains. If the system will contain one chain and many segments + the PDB file will not be created in a correct way. + + :arg filename: name of the PDB file which will be saved for visualization, + it will contain the results in occupancy column. + :type filename: str + + :arg ligand_sele: ligand selection, + by default is 'all not (protein or water or ion)'. + :type ligand_sele: str + """ + + if self._freq_interactors is None: + raise ValueError('Please calculate frequent interactors using getFrequentInteractors.') + + atoms = self._atoms + dictOfInteractions = self._freq_interactors + ligand_sele = kwargs.pop('ligand_sele', 'all not (protein or water or ion)') + + chids_list = np.unique(atoms.getChids()) + freq_contacts_list = [] + + for nr_chid, chid in enumerate(chids_list): + atoms_chid = atoms.ca.select('protein and chain '+chid) + freq_contacts_list_chids = np.zeros(atoms_chid.ca.numAtoms(), dtype=int) + firstElement = atoms_chid.ca.getResnums()[0] + dictOfInteractions_chids = dictOfInteractions[nr_chid] + + for k, v in dictOfInteractions_chids.items(): + res_index = int(k[3:-1]) + freq_contacts_list_chids[res_index - firstElement] = v + + freq_contacts_list.extend(freq_contacts_list_chids) + + freq_contacts_list = np.array(freq_contacts_list) + + from collections import Counter + lista_ext = [] + ligands = atoms.select(ligand_sele) + atoms = atoms.select("protein and noh") + ligand_occupancy = np.zeros(len(ligands.getResnums())) + + aa_counter = Counter(atoms.getResindices()) + calphas = atoms.select('name CA') + for i in range(calphas.numAtoms()): + # in PDB values are normalized to 100 (max value) + lista_ext.extend(list(aa_counter.values())[i]*[round((freq_contacts_list[i]/np.max(freq_contacts_list)*100), 8)]) + + lista_ext.extend(ligand_occupancy) + + kw = {'occupancy': lista_ext} + if 'filename' in kwargs: + writePDB(kwargs['filename'], atoms+ligands, **kw) + LOGGER.info('PDB file saved.') + else: + writePDB('filename', atoms+ligands, **kw) + LOGGER.info('PDB file saved.') + + return freq_contacts_list + diff --git a/prody/proteins/pdbfile.py b/prody/proteins/pdbfile.py index 3d0366479..5fbd270f9 100644 --- a/prody/proteins/pdbfile.py +++ b/prody/proteins/pdbfile.py @@ -769,8 +769,7 @@ def _parsePDBLines(atomgroup, lines, split, model, chain, subset, elements = np.concatenate((elements, np.zeros(asize, ATOMIC_FIELDS['element'].dtype))) if anisou is not None: - anisou = np.concatenate((anisou, np.zeros((asize, 6), - ATOMIC_FIELDS['anisou'].dtype))) + anisou = np.concatenate((anisou, np.zeros((asize, 6), float))) if siguij is not None: siguij = np.concatenate((siguij, np.zeros((asize, 6), ATOMIC_FIELDS['siguij'].dtype))) @@ -840,9 +839,12 @@ def _parsePDBLines(atomgroup, lines, split, model, chain, subset, if END: coordinates.resize((acount, 3), refcheck=False) if addcoords: - atomgroup.addCoordset(coordinates) + atomgroup.addCoordset(coordinates, anisous=anisou) else: atomgroup._setCoords(coordinates) + if isPDB and anisou is not None: + anisou.resize((acount, 6), refcheck=False) + atomgroup.setAnisous(anisou / 10000) else: coordsets = np.zeros((int(diff//acount+1), acount, 3)) coordsets[0] = coordinates[:acount] @@ -905,8 +907,7 @@ def _parsePDBLines(atomgroup, lines, split, model, chain, subset, elif isPDB and startswith == 'ANISOU': if anisou is None: anisou = True - anisou = np.zeros((alength, 6), - dtype=ATOMIC_FIELDS['anisou'].dtype) + anisou = np.zeros((alength, 6), dtype=float) alt = line[16] if alt not in which_altlocs and which_altlocs != 'all': @@ -956,7 +957,7 @@ def _parsePDBLines(atomgroup, lines, split, model, chain, subset, # this means last line was an ATOM line, so atomgroup is not decorated coordinates.resize((acount, 3), refcheck=False) if addcoords: - atomgroup.addCoordset(coordinates) + atomgroup.addCoordset(coordinates, anisous=anisou) else: atomgroup._setCoords(coordinates) atomnames.resize(acount, refcheck=False) @@ -1026,6 +1027,7 @@ def _evalAltlocs(atomgroup, altloc, chainids, resnums, resnames, atomnames): indices = {} for key in altloc_keys: xyz = atomgroup.getCoords() + anisou = atomgroup.getAnisous() success = 0 lines = altloc[key] for line, i in lines: @@ -1052,7 +1054,7 @@ def _evalAltlocs(atomgroup, altloc, chainids, resnums, resnames, atomnames): LOGGER.warn("failed to parse altloc {0} at line {1}, " "residue name mismatch (expected {2}, " "parsed {3})".format(repr(key), i+1, repr(rn), - repr(arn))) + repr(arn))) continue index = ids[(ans == aan).nonzero()[0]] if len(index) != 1: @@ -1060,21 +1062,35 @@ def _evalAltlocs(atomgroup, altloc, chainids, resnums, resnames, atomnames): " {2} not found in the residue" .format(repr(key), i+1, repr(aan))) continue - try: - xyz[index[0], 0] = float(line[30:38]) - xyz[index[0], 1] = float(line[38:46]) - xyz[index[0], 2] = float(line[46:54]) - except: - LOGGER.warn('failed to parse altloc {0} at line {1}, could' - ' not read coordinates'.format(repr(key), i+1)) - continue - success += 1 + + if line.startswith('ATOM '): + try: + xyz[index[0], 0] = float(line[30:38]) + xyz[index[0], 1] = float(line[38:46]) + xyz[index[0], 2] = float(line[46:54]) + except: + LOGGER.warn('failed to parse altloc {0} at line {1}, could' + ' not read coordinates'.format(repr(key), i+1)) + continue + success += 1 + elif line.startswith('ANISOU'): + try: + anisou[index[0], 0] = line[28:35] + anisou[index[0], 1] = line[35:42] + anisou[index[0], 2] = line[43:49] + anisou[index[0], 3] = line[49:56] + anisou[index[0], 4] = line[56:63] + anisou[index[0], 5] = line[63:70] + except: + LOGGER.warn('failed to parse altloc {0} at line {1}, could' + ' not read anisous'.format(repr(key), i+1)) + success += 1 LOGGER.info('{0} out of {1} altloc {2} lines were parsed.' .format(success, len(lines), repr(key))) if success > 0: LOGGER.info('Altloc {0} is appended as a coordinate set to ' 'atomgroup {1}.'.format(repr(key), atomgroup.getTitle())) - atomgroup.addCoordset(xyz, label='altloc ' + key) + atomgroup.addCoordset(xyz, label='altloc ' + key, anisous=anisou) #HELIXLINE = ('HELIX %3d %3s %-3s %1s %4d%1s %-3s %1s %4d%1s%2d' @@ -1227,7 +1243,11 @@ def writePDBStream(stream, atoms, csets=None, **kwargs): NB: ChimeraX seems to prefer hybrid36 and may have problems with hexadecimal. :type hybrid36: bool """ - + keepACSI = False + if hasattr(atoms, 'getACSIndex'): + initialACSI = atoms.getACSIndex() + keepACSI = True + renumber = kwargs.get('renumber', True) remark = str(atoms) @@ -1359,10 +1379,6 @@ def writePDBStream(stream, atoms, csets=None, **kwargs): if charges2[i] == '0+': charges2[i] = ' ' - anisous = atoms._getAnisous() - if anisous is not None: - anisous = np.array(anisous * 10000, dtype=int) - # write remarks stream.write('REMARK {0}\n'.format(remark)) @@ -1425,6 +1441,12 @@ def writePDBStream(stream, atoms, csets=None, **kwargs): write = stream.write num_ter_lines = 0 for m, coords in enumerate(coordsets): + + atoms.setACSIndex(m) + anisous = atoms._getAnisous() + if anisous is not None: + anisous = np.array(anisous * 10000, dtype=int) + if multi: write('MODEL{0:9d}\n'.format(m+1)) @@ -1596,6 +1618,9 @@ def writePDBStream(stream, atoms, csets=None, **kwargs): write('END ' + " "*74 + '\n') + if keepACSI: + atoms.setACSIndex(initialACSI) + writePDBStream.__doc__ += _writePDBdoc def writePDB(filename, atoms, csets=None, autoext=True, **kwargs): diff --git a/prody/tests/database/test_pfam.py b/prody/tests/database/test_pfam.py new file mode 100644 index 000000000..adaef5276 --- /dev/null +++ b/prody/tests/database/test_pfam.py @@ -0,0 +1,236 @@ +"""This module contains unit tests for :mod:`prody.database.pfam` module.""" + +from numpy import tile, array, arange, ones +from numpy.testing import assert_allclose + +from prody.tests import unittest +from prody.database.pfam import searchPfam +from prody.database.pfam import fetchPfamMSA +from prody.database.pfam import parsePfamPDBs + +from prody.atomic.selection import Selection + +import os +import shutil + +from prody import LOGGER +LOGGER.verbosity = 'none' + +class TestSearchPfam(unittest.TestCase): + + @classmethod + def setUpClass(self): + self.workdir = 'pfam_search_tests' + if not os.path.exists(self.workdir): + os.mkdir(self.workdir) + os.chdir(self.workdir) + + self.queries = ['P19491', '6qkcB', '6qkcI'] + + def testUniprotAccMulti(self): + """Test the outcome of a simple search scenario using a Uniprot Accession + for a multi-domain protein, AMPAR GluA2.""" + + a = searchPfam(self.queries[0]) + + self.assertIsInstance(a, dict, + 'searchPfam failed to return a dict instance') + + self.assertEqual(sorted(list(a.keys())), + ['PF00060', 'PF00497', 'PF01094', 'PF10613'], + 'searchPfam failed to return the right domain family IDs') + + def testPdbIdChMulti(self): + """Test the outcome of a simple search scenario using a PDB ID + and chain ID for the same multi-domain protein from specifying chain B.""" + + a = searchPfam(self.queries[1]) + + self.assertIsInstance(a, dict, + 'searchPfam failed to return a dict instance') + + self.assertEqual(sorted(list(a.keys())), ['PF00060', 'PF00497', 'PF01094', 'PF10613'], + 'searchPfam failed to return the right domain family IDs for AMPAR') + + def testPdbIdChSingle(self): + """Test the outcome of a simple search scenario using a PDB ID + and chain ID to get the single domain protein TARP g8 from chain I.""" + + a = searchPfam(self.queries[2]) + + self.assertIsInstance(a, dict, + 'searchPfam failed to return a dict instance') + + self.assertEqual(sorted(list(a.keys())), + ['PF00822'], + 'searchPfam failed to return the right domain family IDs for TARP') + + @classmethod + def tearDownClass(self): + os.chdir('..') + shutil.rmtree(self.workdir) + + +class TestFetchPfamMSA(unittest.TestCase): + + @classmethod + def setUpClass(self): + self.query = 'PF00822' + + self.workdir = 'pfam_msa_tests' + if not os.path.exists(self.workdir): + os.mkdir(self.workdir) + os.chdir(self.workdir) + + def testDefault(self): + """Test the outcome of fetching the domain MSA for claudins + with default parameters.""" + + b = fetchPfamMSA(self.query) + + self.assertIsInstance(b, str, + 'fetchPfamMSA failed to return a str instance') + + self.assertEqual(b, 'PF00822_full.sth') + + self.assertTrue(os.path.exists(b)) + + + def testSeed(self): + """Test the outcome of fetching the domain MSA for claudins + with the alignment type argument set to seed""" + + b = fetchPfamMSA(self.query, "seed") + + self.assertIsInstance(b, str, + 'fetchPfamMSA failed to return a str instance') + + self.assertEqual(b, 'PF00822_seed.sth') + + self.assertTrue(os.path.exists(b)) + + def testFolder(self): + """Test the outcome of fetching the domain MSA for claudins + with keyword folder set to a folder that is made especially.""" + + folder = "new_folder" + os.mkdir(folder) + b = fetchPfamMSA(self.query, folder=folder) + + self.assertIsInstance(b, str, + 'fetchPfamMSA failed to return a str instance') + + self.assertEqual(b, 'new_folder/PF00822_full.sth') + + self.assertTrue(os.path.exists(b)) + + @classmethod + def tearDownClass(self): + os.chdir('..') + shutil.rmtree(self.workdir) + + +class TestParsePfamPDBs(unittest.TestCase): + + @classmethod + def setUpClass(self): + self.queries = ['PF20446', 'Q57ZF2', 'P40682'] + + self.workdir = 'pfam_pdb_tests' + if not os.path.exists(self.workdir): + os.mkdir(self.workdir) + os.chdir(self.workdir) + + def testPfamIdDefault(self): + """Test the outcome of parsing PDBs for a tiny family + of ABC class ATPase N-terminal domains (5 members) + with the Pfam ID and default parameters.""" + + b = parsePfamPDBs(self.queries[0]) + + self.assertIsInstance(b, list, + 'parsePfamPDBs failed to return a list instance') + + self.assertIsInstance(b[0], Selection, + 'parsePfamPDBs failed to return a list of Selection instances') + + self.assertEqual(len(b), 5, + 'parsePfamPDBs failed to return a list of length 5') + + + def testUniprotDefault(self): + """Test the outcome of parsing PDBs for a tiny family + of ABC class ATPase N-terminal domains (5 members) + with the Uniprot long ID and default parameters.""" + + b = parsePfamPDBs(self.queries[1]) + + self.assertIsInstance(b, list, + 'parsePfamPDBs failed to return a list instance') + + self.assertIsInstance(b[0], Selection, + 'parsePfamPDBs failed to return a list of Selection instances') + + self.assertEqual(len(b), 5, + 'parsePfamPDBs failed to return a list of length 5') + + + def testMultiDomainDefault(self): + """Test the outcome of parsing PDBs using a V-type proton ATPase subunit S1, + which has two domains but few relatives. Default parameters should + return Selection objects containing the first domain.""" + + b = parsePfamPDBs(self.queries[2]) + + self.assertIsInstance(b, list, + 'parsePfamPDBs failed to return a list instance') + + self.assertIsInstance(b[0], Selection, + 'parsePfamPDBs failed to return a list of Selection instances') + + self.assertEqual(len(b), 7, + 'parsePfamPDBs failed to return a list of length 7') + + self.assertEqual(b[0].getResnums()[0], 262, + 'parsePfamPDBs failed to return a first Selection with first resnum 262') + + def testMultiDomainStart1(self): + """Test the outcome of parsing PDBs using a V-type proton ATPase subunit S1, + which has two domains but few relatives. Using start=1 should be like default and + return Selection objects containing the first domain.""" + + b = parsePfamPDBs(self.queries[2], start=1) + + self.assertIsInstance(b, list, + 'parsePfamPDBs failed to return a list instance') + + self.assertIsInstance(b[0], Selection, + 'parsePfamPDBs failed to return a list of Selection instances') + + self.assertEqual(len(b), 7, + 'parsePfamPDBs failed to return a list of length 7') + + self.assertEqual(b[0].getResnums()[0], 262, + 'parsePfamPDBs failed to return a first Selection with first resnum 262') + + def testMultiDomainStart2(self): + """Test the outcome of parsing PDBs using a V-type proton ATPase subunit S1, + which has two domains but few relatives. Setting start to 418 should + return Selection objects containing the second domain.""" + + b = parsePfamPDBs(self.queries[2], start=418) + + self.assertIsInstance(b, list, + 'parsePfamPDBs failed to return a list instance') + + self.assertIsInstance(b[0], Selection, + 'parsePfamPDBs failed to return a list of Selection instances') + + self.assertEqual(b[0].getResnums()[0], 418, + 'parsePfamPDBs failed to return a first Selection with first resnum 418') + + @classmethod + def tearDownClass(self): + os.chdir('..') + shutil.rmtree(self.workdir) + diff --git a/prody/tests/datafiles/__init__.py b/prody/tests/datafiles/__init__.py index 222e17073..c2d5f0384 100644 --- a/prody/tests/datafiles/__init__.py +++ b/prody/tests/datafiles/__init__.py @@ -270,6 +270,28 @@ 'models': 1, 'biomols': 2 }, + '6flr': { + 'pdb': '6flr', + 'file': 'pdb6flr.pdb', + 'atoms_single': 6073, + 'ca_atoms_single': 741, + 'atoms_altloc': 6086, + 'ca_atoms_altloc': 743, + 'num_altlocs': 2, + 'biomols': 1, + 'anisousA': array([[1.3327, 0.8826, 0.7048, 0.0444, 0.3365, 0.1618]]), + 'anisousB': array([[1.3306, 0.8825, 0.7058, 0.0438, 0.338 , 0.1608]]) + }, + '6flr_sel': { + 'pdb': '6flr', + 'file': 'pdb6flr_B234.pdb', + 'atoms': 1, + 'ca_atoms': 1, + 'models': 2, + 'biomols': 1, + 'anisousA': array([[1.3327, 0.8826, 0.7048, 0.0444, 0.3365, 0.1618]]), + 'anisousB': array([[1.3306, 0.8825, 0.7058, 0.0438, 0.338 , 0.1608]]) + }, 'gromacs': { 'pdb': '6fpj', 'file': 'pdb6fpj_Bb_fixed_solv_ions.pdb', diff --git a/prody/tests/datafiles/pdb6flr.pdb b/prody/tests/datafiles/pdb6flr.pdb new file mode 100644 index 000000000..2b2193618 --- /dev/null +++ b/prody/tests/datafiles/pdb6flr.pdb @@ -0,0 +1,12715 @@ +HEADER MEMBRANE PROTEIN 27-JAN-18 6FLR +TITLE SUPER-OPEN STRUCTURE OF THE AMPAR GLUA3 N-TERMINAL DOMAIN +COMPND MOL_ID: 1; +COMPND 2 MOLECULE: GLUTAMATE RECEPTOR 3; +COMPND 3 CHAIN: A, B; +COMPND 4 SYNONYM: GLUR-3,AMPA-SELECTIVE GLUTAMATE RECEPTOR 3,GLUR-C,GLUR-K3, +COMPND 5 GLUTAMATE RECEPTOR IONOTROPIC,AMPA 3,GLUA3; +COMPND 6 ENGINEERED: YES +SOURCE MOL_ID: 1; +SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; +SOURCE 3 ORGANISM_COMMON: RAT; +SOURCE 4 ORGANISM_TAXID: 10116; +SOURCE 5 GENE: GRIA3, GLUR3; +SOURCE 6 EXPRESSION_SYSTEM: HOMO SAPIENS; +SOURCE 7 EXPRESSION_SYSTEM_TAXID: 9606 +KEYWDS LIGAND-GATED ION CHANNEL, MEMBRANE PROTEIN, AMPA RECEPTOR +EXPDTA X-RAY DIFFRACTION +AUTHOR J.GARCIA-NAFRIA +REVDAT 3 29-JUL-20 6FLR 1 COMPND REMARK HETNAM LINK +REVDAT 3 2 1 SITE +REVDAT 2 13-FEB-19 6FLR 1 JRNL +REVDAT 1 19-DEC-18 6FLR 0 +JRNL AUTH J.Y.LEE,J.KRIEGER,B.HERGUEDAS,J.GARCIA-NAFRIA,A.DUTTA, +JRNL AUTH 2 S.A.SHAIKH,I.H.GREGER,I.BAHAR +JRNL TITL DRUGGABILITY SIMULATIONS AND X-RAY CRYSTALLOGRAPHY REVEAL A +JRNL TITL 2 LIGAND-BINDING SITE IN THE GLUA3 AMPA RECEPTOR N-TERMINAL +JRNL TITL 3 DOMAIN. +JRNL REF STRUCTURE V. 27 241 2019 +JRNL REFN ISSN 1878-4186 +JRNL PMID 30528594 +JRNL DOI 10.1016/J.STR.2018.10.017 +REMARK 2 +REMARK 2 RESOLUTION. 2.51 ANGSTROMS. +REMARK 3 +REMARK 3 REFINEMENT. +REMARK 3 PROGRAM : REFMAC 5.8.0207 +REMARK 3 AUTHORS : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,STEINER, +REMARK 3 : NICHOLLS,WINN,LONG,VAGIN +REMARK 3 +REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD +REMARK 3 +REMARK 3 DATA USED IN REFINEMENT. +REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.51 +REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 82.77 +REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL +REMARK 3 COMPLETENESS FOR RANGE (%) : 99.9 +REMARK 3 NUMBER OF REFLECTIONS : 26508 +REMARK 3 +REMARK 3 FIT TO DATA USED IN REFINEMENT. +REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT +REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM +REMARK 3 R VALUE (WORKING + TEST SET) : 0.220 +REMARK 3 R VALUE (WORKING SET) : 0.218 +REMARK 3 FREE R VALUE : 0.257 +REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.000 +REMARK 3 FREE R VALUE TEST SET COUNT : 1401 +REMARK 3 +REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. +REMARK 3 TOTAL NUMBER OF BINS USED : 20 +REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.51 +REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.58 +REMARK 3 REFLECTION IN BIN (WORKING SET) : 1941 +REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 99.85 +REMARK 3 BIN R VALUE (WORKING SET) : 0.3440 +REMARK 3 BIN FREE R VALUE SET COUNT : 87 +REMARK 3 BIN FREE R VALUE : 0.3840 +REMARK 3 +REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. +REMARK 3 PROTEIN ATOMS : 5958 +REMARK 3 NUCLEIC ACID ATOMS : 0 +REMARK 3 HETEROGEN ATOMS : 70 +REMARK 3 SOLVENT ATOMS : 45 +REMARK 3 +REMARK 3 B VALUES. +REMARK 3 FROM WILSON PLOT (A**2) : NULL +REMARK 3 MEAN B VALUE (OVERALL, A**2) : 55.52 +REMARK 3 OVERALL ANISOTROPIC B VALUE. +REMARK 3 B11 (A**2) : 1.53000 +REMARK 3 B22 (A**2) : -2.70000 +REMARK 3 B33 (A**2) : 1.17000 +REMARK 3 B12 (A**2) : 0.00000 +REMARK 3 B13 (A**2) : 0.00000 +REMARK 3 B23 (A**2) : 0.00000 +REMARK 3 +REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. +REMARK 3 ESU BASED ON R VALUE (A): 0.935 +REMARK 3 ESU BASED ON FREE R VALUE (A): 0.315 +REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.274 +REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 27.412 +REMARK 3 +REMARK 3 CORRELATION COEFFICIENTS. +REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.939 +REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.908 +REMARK 3 +REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT +REMARK 3 BOND LENGTHS REFINED ATOMS (A): 6186 ; 0.010 ; 0.019 +REMARK 3 BOND LENGTHS OTHERS (A): 5477 ; 0.001 ; 0.020 +REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 8392 ; 1.378 ; 1.935 +REMARK 3 BOND ANGLES OTHERS (DEGREES): 12625 ; 0.777 ; 3.000 +REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 738 ; 5.717 ; 5.000 +REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 321 ;34.069 ;23.614 +REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 981 ;13.214 ;15.000 +REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 45 ;15.500 ;15.000 +REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 923 ; 0.072 ; 0.200 +REMARK 3 GENERAL PLANES REFINED ATOMS (A): 6931 ; 0.005 ; 0.020 +REMARK 3 GENERAL PLANES OTHERS (A): 1396 ; 0.001 ; 0.020 +REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL +REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL +REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL +REMARK 3 +REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT +REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 2961 ; 1.299 ; 2.785 +REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 2960 ; 1.299 ; 2.785 +REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 3690 ; 2.367 ; 4.163 +REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): 3691 ; 2.367 ; 4.164 +REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 3225 ; 1.336 ; 3.018 +REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): 3226 ; 1.336 ; 3.018 +REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): 4700 ; 2.256 ; 4.471 +REMARK 3 LONG RANGE B REFINED ATOMS (A**2): 6752 ; 5.555 ;32.214 +REMARK 3 LONG RANGE B OTHER ATOMS (A**2): 6751 ; 5.550 ;32.204 +REMARK 3 +REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT +REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL +REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL +REMARK 3 +REMARK 3 NCS RESTRAINTS STATISTICS +REMARK 3 NCS TYPE: LOCAL +REMARK 3 NUMBER OF DIFFERENT NCS PAIRS : 1 +REMARK 3 GROUP CHAIN1 RANGE CHAIN2 RANGE COUNT RMS WEIGHT +REMARK 3 1 A 2 380 B 2 380 11619 0.08 0.05 +REMARK 3 +REMARK 3 TLS DETAILS +REMARK 3 NUMBER OF TLS GROUPS : 2 +REMARK 3 +REMARK 3 TLS GROUP : 1 +REMARK 3 NUMBER OF COMPONENTS GROUP : 1 +REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI +REMARK 3 RESIDUE RANGE : A 2 A 381 +REMARK 3 ORIGIN FOR THE GROUP (A): 12.5231 17.9827 30.4454 +REMARK 3 T TENSOR +REMARK 3 T11: 0.2949 T22: 0.1241 +REMARK 3 T33: 0.0081 T12: 0.0538 +REMARK 3 T13: 0.0199 T23: -0.0014 +REMARK 3 L TENSOR +REMARK 3 L11: 1.2416 L22: 3.0196 +REMARK 3 L33: 1.5122 L12: 0.9408 +REMARK 3 L13: 0.4041 L23: 0.4013 +REMARK 3 S TENSOR +REMARK 3 S11: 0.0391 S12: 0.0934 S13: -0.0576 +REMARK 3 S21: -0.1087 S22: -0.0188 S23: -0.0537 +REMARK 3 S31: 0.0721 S32: 0.0972 S33: -0.0203 +REMARK 3 +REMARK 3 TLS GROUP : 2 +REMARK 3 NUMBER OF COMPONENTS GROUP : 1 +REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI +REMARK 3 RESIDUE RANGE : B 2 B 380 +REMARK 3 ORIGIN FOR THE GROUP (A): 32.7795 3.6488 61.8533 +REMARK 3 T TENSOR +REMARK 3 T11: 0.3865 T22: 0.3228 +REMARK 3 T33: 0.0060 T12: 0.1216 +REMARK 3 T13: -0.0100 T23: 0.0270 +REMARK 3 L TENSOR +REMARK 3 L11: 2.4381 L22: 2.9718 +REMARK 3 L33: 1.7643 L12: 0.9827 +REMARK 3 L13: -0.9083 L23: -0.4937 +REMARK 3 S TENSOR +REMARK 3 S11: -0.1028 S12: -0.1007 S13: -0.0794 +REMARK 3 S21: 0.3126 S22: 0.0853 S23: -0.0484 +REMARK 3 S31: 0.1748 S32: 0.1583 S33: 0.0175 +REMARK 3 +REMARK 3 BULK SOLVENT MODELLING. +REMARK 3 METHOD USED : MASK +REMARK 3 PARAMETERS FOR MASK CALCULATION +REMARK 3 VDW PROBE RADIUS : 1.20 +REMARK 3 ION PROBE RADIUS : 0.80 +REMARK 3 SHRINKAGE RADIUS : 0.80 +REMARK 3 +REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING +REMARK 3 POSITIONS +REMARK 4 +REMARK 4 6FLR COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 +REMARK 100 +REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 27-JAN-18. +REMARK 100 THE DEPOSITION ID IS D_1200008557. +REMARK 200 +REMARK 200 EXPERIMENTAL DETAILS +REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION +REMARK 200 DATE OF DATA COLLECTION : 12-JUL-12 +REMARK 200 TEMPERATURE (KELVIN) : 100 +REMARK 200 PH : NULL +REMARK 200 NUMBER OF CRYSTALS USED : 1 +REMARK 200 +REMARK 200 SYNCHROTRON (Y/N) : Y +REMARK 200 RADIATION SOURCE : ESRF +REMARK 200 BEAMLINE : ID14-4 +REMARK 200 X-RAY GENERATOR MODEL : NULL +REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M +REMARK 200 WAVELENGTH OR RANGE (A) : 0.939 +REMARK 200 MONOCHROMATOR : NULL +REMARK 200 OPTICS : NULL +REMARK 200 +REMARK 200 DETECTOR TYPE : CCD +REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315 +REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS +REMARK 200 DATA SCALING SOFTWARE : SCALA +REMARK 200 +REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 26508 +REMARK 200 RESOLUTION RANGE HIGH (A) : 2.510 +REMARK 200 RESOLUTION RANGE LOW (A) : 82.770 +REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL +REMARK 200 +REMARK 200 OVERALL. +REMARK 200 COMPLETENESS FOR RANGE (%) : 99.9 +REMARK 200 DATA REDUNDANCY : 7.100 +REMARK 200 R MERGE (I) : NULL +REMARK 200 R SYM (I) : NULL +REMARK 200 FOR THE DATA SET : 11.7000 +REMARK 200 +REMARK 200 IN THE HIGHEST RESOLUTION SHELL. +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.51 +REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.57 +REMARK 200 COMPLETENESS FOR SHELL (%) : 99.9 +REMARK 200 DATA REDUNDANCY IN SHELL : 7.40 +REMARK 200 R MERGE FOR SHELL (I) : NULL +REMARK 200 R SYM FOR SHELL (I) : NULL +REMARK 200 FOR SHELL : 1.800 +REMARK 200 +REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH +REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT +REMARK 200 SOFTWARE USED: PHASER +REMARK 200 STARTING MODEL: 3O21 +REMARK 200 +REMARK 200 REMARK: NULL +REMARK 280 +REMARK 280 CRYSTAL +REMARK 280 SOLVENT CONTENT, VS (%): 44.20 +REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.20 +REMARK 280 +REMARK 280 CRYSTALLIZATION CONDITIONS: 18% PEG3350 AND 0.2 M AMMONIUM +REMARK 280 CITRATE, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 293K +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY +REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21 +REMARK 290 +REMARK 290 SYMOP SYMMETRY +REMARK 290 NNNMMM OPERATOR +REMARK 290 1555 X,Y,Z +REMARK 290 2555 -X+1/2,-Y,Z+1/2 +REMARK 290 3555 -X,Y+1/2,-Z+1/2 +REMARK 290 4555 X+1/2,-Y+1/2,-Z +REMARK 290 +REMARK 290 WHERE NNN -> OPERATOR NUMBER +REMARK 290 MMM -> TRANSLATION VECTOR +REMARK 290 +REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS +REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM +REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY +REMARK 290 RELATED MOLECULES. +REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 28.09800 +REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 +REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 67.10000 +REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 +REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 52.57250 +REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 67.10000 +REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 28.09800 +REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 52.57250 +REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 +REMARK 290 +REMARK 290 REMARK: NULL +REMARK 300 +REMARK 300 BIOMOLECULE: 1 +REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM +REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN +REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON +REMARK 300 BURIED SURFACE AREA. +REMARK 350 +REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN +REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE +REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS +REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND +REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. +REMARK 350 +REMARK 350 BIOMOLECULE: 1 +REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC +REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC +REMARK 350 SOFTWARE USED: PISA +REMARK 350 TOTAL BURIED SURFACE AREA: 2520 ANGSTROM**2 +REMARK 350 SURFACE AREA OF THE COMPLEX: 33870 ANGSTROM**2 +REMARK 350 CHANGE IN SOLVENT FREE ENERGY: 9.0 KCAL/MOL +REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B +REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 +REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 +REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 +REMARK 465 +REMARK 465 MISSING RESIDUES +REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE +REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN +REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) +REMARK 465 +REMARK 465 M RES C SSSEQI +REMARK 465 GLY A 1 +REMARK 465 ARG A 305 +REMARK 465 ARG A 306 +REMARK 465 GLY A 307 +REMARK 465 SER A 308 +REMARK 465 ALA A 309 +REMARK 465 GLY A 310 +REMARK 465 LYS A 361 +REMARK 465 VAL A 362 +REMARK 465 SER A 363 +REMARK 465 GLY A 364 +REMARK 465 GLY A 382 +REMARK 465 THR A 383 +REMARK 465 HIS A 384 +REMARK 465 HIS A 385 +REMARK 465 HIS A 386 +REMARK 465 HIS A 387 +REMARK 465 HIS A 388 +REMARK 465 HIS A 389 +REMARK 465 GLY B 1 +REMARK 465 GLN B 34 +REMARK 465 ARG B 305 +REMARK 465 ARG B 306 +REMARK 465 GLY B 307 +REMARK 465 SER B 308 +REMARK 465 ALA B 309 +REMARK 465 LYS B 361 +REMARK 465 VAL B 362 +REMARK 465 SER B 381 +REMARK 465 GLY B 382 +REMARK 465 THR B 383 +REMARK 465 HIS B 384 +REMARK 465 HIS B 385 +REMARK 465 HIS B 386 +REMARK 465 HIS B 387 +REMARK 465 HIS B 388 +REMARK 465 HIS B 389 +REMARK 470 +REMARK 470 MISSING ATOM +REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; +REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; +REMARK 470 I=INSERTION CODE): +REMARK 470 M RES CSSEQI ATOMS +REMARK 470 ARG A 14 CG CD NE CZ NH1 NH2 +REMARK 470 ASP A 51 CG OD1 OD2 +REMARK 470 ASP A 104 CG OD1 OD2 +REMARK 470 LYS A 169 CG CD CE NZ +REMARK 470 ARG A 183 CG CD NE CZ NH1 NH2 +REMARK 470 LYS A 210 CG CD CE NZ +REMARK 470 ARG A 213 CG CD NE CZ NH1 NH2 +REMARK 470 ARG A 265 CG CD NE CZ NH1 NH2 +REMARK 470 GLU A 266 CG CD OE1 OE2 +REMARK 470 ARG B 14 CG CD NE CZ NH1 NH2 +REMARK 470 GLU B 38 CG CD OE1 OE2 +REMARK 470 LYS B 39 CG CD CE NZ +REMARK 470 LYS B 129 CG CD CE NZ +REMARK 470 LYS B 169 CG CD CE NZ +REMARK 470 ARG B 183 CG CD NE CZ NH1 NH2 +REMARK 470 GLU B 203 CG CD OE1 OE2 +REMARK 470 LYS B 210 CG CD CE NZ +REMARK 470 GLU B 264 CG CD OE1 OE2 +REMARK 470 ARG B 265 CG CD NE CZ NH1 NH2 +REMARK 470 ASN B 315 CG OD1 ND2 +REMARK 470 PRO B 316 CG CD +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT +REMARK 500 +REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. +REMARK 500 +REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE +REMARK 500 ND2 ASN B 352 O5 NAG B 401 1.54 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 500 +REMARK 500 GEOMETRY AND STEREOCHEMISTRY +REMARK 500 SUBTOPIC: TORSION ANGLES +REMARK 500 +REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: +REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; +REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). +REMARK 500 +REMARK 500 STANDARD TABLE: +REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) +REMARK 500 +REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- +REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 +REMARK 500 +REMARK 500 M RES CSSEQI PSI PHI +REMARK 500 PHE A 109 33.16 70.16 +REMARK 500 ASP A 192 72.44 -110.88 +REMARK 500 SER A 212 -73.05 -119.37 +REMARK 500 LEU A 313 64.18 -110.16 +REMARK 500 ARG A 376 -143.22 61.25 +REMARK 500 ASP B 192 72.28 -110.33 +REMARK 500 SER B 212 -71.77 -121.66 +REMARK 500 ALA B 317 167.81 96.20 +REMARK 500 SER B 365 49.93 -165.48 +REMARK 500 ARG B 376 -143.17 61.08 +REMARK 500 +REMARK 500 REMARK: NULL +REMARK 610 +REMARK 610 MISSING HETEROATOM +REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; +REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; +REMARK 610 I=INSERTION CODE): +REMARK 610 M RES C SSEQI +REMARK 610 NAG A 401 +REMARK 610 NAG A 402 +REMARK 610 NAG A 403 +REMARK 610 NAG B 402 +DBREF 6FLR A 1 381 UNP P19492 GRIA3_RAT 23 403 +DBREF 6FLR B 1 381 UNP P19492 GRIA3_RAT 23 403 +SEQADV 6FLR GLY A 382 UNP P19492 EXPRESSION TAG +SEQADV 6FLR THR A 383 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 384 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 385 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 386 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 387 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 388 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS A 389 UNP P19492 EXPRESSION TAG +SEQADV 6FLR GLY B 382 UNP P19492 EXPRESSION TAG +SEQADV 6FLR THR B 383 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 384 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 385 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 386 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 387 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 388 UNP P19492 EXPRESSION TAG +SEQADV 6FLR HIS B 389 UNP P19492 EXPRESSION TAG +SEQRES 1 A 389 GLY PHE PRO ASN THR ILE SER ILE GLY GLY LEU PHE MET +SEQRES 2 A 389 ARG ASN THR VAL GLN GLU HIS SER ALA PHE ARG PHE ALA +SEQRES 3 A 389 VAL GLN LEU TYR ASN THR ASN GLN ASN THR THR GLU LYS +SEQRES 4 A 389 PRO PHE HIS LEU ASN TYR HIS VAL ASP HIS LEU ASP SER +SEQRES 5 A 389 SER ASN SER PHE SER VAL THR ASN ALA PHE CYS SER GLN +SEQRES 6 A 389 PHE SER ARG GLY VAL TYR ALA ILE PHE GLY PHE TYR ASP +SEQRES 7 A 389 GLN MET SER MET ASN THR LEU THR SER PHE CYS GLY ALA +SEQRES 8 A 389 LEU HIS THR SER PHE VAL THR PRO SER PHE PRO THR ASP +SEQRES 9 A 389 ALA ASP VAL GLN PHE VAL ILE GLN MET ARG PRO ALA LEU +SEQRES 10 A 389 LYS GLY ALA ILE LEU SER LEU LEU SER TYR TYR LYS TRP +SEQRES 11 A 389 GLU LYS PHE VAL TYR LEU TYR ASP THR GLU ARG GLY PHE +SEQRES 12 A 389 SER VAL LEU GLN ALA ILE MET GLU ALA ALA VAL GLN ASN +SEQRES 13 A 389 ASN TRP GLN VAL THR ALA ARG SER VAL GLY ASN ILE LYS +SEQRES 14 A 389 ASP VAL GLN GLU PHE ARG ARG ILE ILE GLU GLU MET ASP +SEQRES 15 A 389 ARG ARG GLN GLU LYS ARG TYR LEU ILE ASP CYS GLU VAL +SEQRES 16 A 389 GLU ARG ILE ASN THR ILE LEU GLU GLN VAL VAL ILE LEU +SEQRES 17 A 389 GLY LYS HIS SER ARG GLY TYR HIS TYR MET LEU ALA ASN +SEQRES 18 A 389 LEU GLY PHE THR ASP ILE LEU LEU GLU ARG VAL MET HIS +SEQRES 19 A 389 GLY GLY ALA ASN ILE THR GLY PHE GLN ILE VAL ASN ASN +SEQRES 20 A 389 GLU ASN PRO MET VAL GLN GLN PHE ILE GLN ARG TRP VAL +SEQRES 21 A 389 ARG LEU ASP GLU ARG GLU PHE PRO GLU ALA LYS ASN ALA +SEQRES 22 A 389 PRO LEU LYS TYR THR SER ALA LEU THR HIS ASP ALA ILE +SEQRES 23 A 389 LEU VAL ILE ALA GLU ALA PHE ARG TYR LEU ARG ARG GLN +SEQRES 24 A 389 ARG VAL ASP VAL SER ARG ARG GLY SER ALA GLY ASP CYS +SEQRES 25 A 389 LEU ALA ASN PRO ALA VAL PRO TRP SER GLN GLY ILE ASP +SEQRES 26 A 389 ILE GLU ARG ALA LEU LYS MET VAL GLN VAL GLN GLY MET +SEQRES 27 A 389 THR GLY ASN ILE GLN PHE ASP THR TYR GLY ARG ARG THR +SEQRES 28 A 389 ASN TYR THR ILE ASP VAL TYR GLU MET LYS VAL SER GLY +SEQRES 29 A 389 SER ARG LYS ALA GLY TYR TRP ASN GLU TYR GLU ARG PHE +SEQRES 30 A 389 VAL PRO PHE SER GLY THR HIS HIS HIS HIS HIS HIS +SEQRES 1 B 389 GLY PHE PRO ASN THR ILE SER ILE GLY GLY LEU PHE MET +SEQRES 2 B 389 ARG ASN THR VAL GLN GLU HIS SER ALA PHE ARG PHE ALA +SEQRES 3 B 389 VAL GLN LEU TYR ASN THR ASN GLN ASN THR THR GLU LYS +SEQRES 4 B 389 PRO PHE HIS LEU ASN TYR HIS VAL ASP HIS LEU ASP SER +SEQRES 5 B 389 SER ASN SER PHE SER VAL THR ASN ALA PHE CYS SER GLN +SEQRES 6 B 389 PHE SER ARG GLY VAL TYR ALA ILE PHE GLY PHE TYR ASP +SEQRES 7 B 389 GLN MET SER MET ASN THR LEU THR SER PHE CYS GLY ALA +SEQRES 8 B 389 LEU HIS THR SER PHE VAL THR PRO SER PHE PRO THR ASP +SEQRES 9 B 389 ALA ASP VAL GLN PHE VAL ILE GLN MET ARG PRO ALA LEU +SEQRES 10 B 389 LYS GLY ALA ILE LEU SER LEU LEU SER TYR TYR LYS TRP +SEQRES 11 B 389 GLU LYS PHE VAL TYR LEU TYR ASP THR GLU ARG GLY PHE +SEQRES 12 B 389 SER VAL LEU GLN ALA ILE MET GLU ALA ALA VAL GLN ASN +SEQRES 13 B 389 ASN TRP GLN VAL THR ALA ARG SER VAL GLY ASN ILE LYS +SEQRES 14 B 389 ASP VAL GLN GLU PHE ARG ARG ILE ILE GLU GLU MET ASP +SEQRES 15 B 389 ARG ARG GLN GLU LYS ARG TYR LEU ILE ASP CYS GLU VAL +SEQRES 16 B 389 GLU ARG ILE ASN THR ILE LEU GLU GLN VAL VAL ILE LEU +SEQRES 17 B 389 GLY LYS HIS SER ARG GLY TYR HIS TYR MET LEU ALA ASN +SEQRES 18 B 389 LEU GLY PHE THR ASP ILE LEU LEU GLU ARG VAL MET HIS +SEQRES 19 B 389 GLY GLY ALA ASN ILE THR GLY PHE GLN ILE VAL ASN ASN +SEQRES 20 B 389 GLU ASN PRO MET VAL GLN GLN PHE ILE GLN ARG TRP VAL +SEQRES 21 B 389 ARG LEU ASP GLU ARG GLU PHE PRO GLU ALA LYS ASN ALA +SEQRES 22 B 389 PRO LEU LYS TYR THR SER ALA LEU THR HIS ASP ALA ILE +SEQRES 23 B 389 LEU VAL ILE ALA GLU ALA PHE ARG TYR LEU ARG ARG GLN +SEQRES 24 B 389 ARG VAL ASP VAL SER ARG ARG GLY SER ALA GLY ASP CYS +SEQRES 25 B 389 LEU ALA ASN PRO ALA VAL PRO TRP SER GLN GLY ILE ASP +SEQRES 26 B 389 ILE GLU ARG ALA LEU LYS MET VAL GLN VAL GLN GLY MET +SEQRES 27 B 389 THR GLY ASN ILE GLN PHE ASP THR TYR GLY ARG ARG THR +SEQRES 28 B 389 ASN TYR THR ILE ASP VAL TYR GLU MET LYS VAL SER GLY +SEQRES 29 B 389 SER ARG LYS ALA GLY TYR TRP ASN GLU TYR GLU ARG PHE +SEQRES 30 B 389 VAL PRO PHE SER GLY THR HIS HIS HIS HIS HIS HIS +HET NAG A 401 14 +HET NAG A 402 14 +HET NAG A 403 14 +HET NAG B 401 14 +HET NAG B 402 14 +HETNAM NAG 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE +FORMUL 3 NAG 5(C8 H15 N O6) +FORMUL 8 HOH *45(H2 O) +HELIX 1 AA1 THR A 16 THR A 32 1 17 +HELIX 2 AA2 ASN A 54 GLY A 69 1 16 +HELIX 3 AA3 SER A 81 LEU A 92 1 12 +HELIX 4 AA4 LEU A 117 TYR A 128 1 12 +HELIX 5 AA5 PHE A 143 ASN A 157 1 15 +HELIX 6 AA6 VAL A 171 ARG A 184 1 14 +HELIX 7 AA7 GLU A 194 GLY A 209 1 16 +HELIX 8 AA8 GLY A 223 ILE A 227 5 5 +HELIX 9 AA9 LEU A 229 GLY A 235 1 7 +HELIX 10 AB1 ASN A 249 VAL A 260 1 12 +HELIX 11 AB2 LYS A 276 ARG A 300 1 25 +HELIX 12 AB3 GLN A 322 VAL A 333 1 12 +HELIX 13 AB4 THR B 16 THR B 32 1 17 +HELIX 14 AB5 ASN B 54 GLY B 69 1 16 +HELIX 15 AB6 SER B 81 HIS B 93 1 13 +HELIX 16 AB7 LEU B 117 TYR B 128 1 12 +HELIX 17 AB8 PHE B 143 ASN B 157 1 15 +HELIX 18 AB9 VAL B 171 ARG B 184 1 14 +HELIX 19 AC1 GLU B 194 GLY B 209 1 16 +HELIX 20 AC2 GLY B 223 ILE B 227 5 5 +HELIX 21 AC3 LEU B 229 GLY B 235 1 7 +HELIX 22 AC4 ASN B 249 VAL B 260 1 12 +HELIX 23 AC5 LYS B 276 ARG B 300 1 25 +HELIX 24 AC6 GLY B 323 MET B 332 1 10 +SHEET 1 AA1 5 HIS A 42 HIS A 49 0 +SHEET 2 AA1 5 THR A 5 PHE A 12 1 N ILE A 6 O HIS A 42 +SHEET 3 AA1 5 ILE A 73 GLY A 75 1 O PHE A 74 N GLY A 9 +SHEET 4 AA1 5 PHE A 96 THR A 98 1 O VAL A 97 N ILE A 73 +SHEET 5 AA1 5 VAL A 110 GLN A 112 1 O ILE A 111 N PHE A 96 +SHEET 1 AA2 8 GLN A 159 SER A 164 0 +SHEET 2 AA2 8 LYS A 132 TYR A 137 1 N TYR A 135 O ARG A 163 +SHEET 3 AA2 8 ARG A 188 ASP A 192 1 O LEU A 190 N VAL A 134 +SHEET 4 AA2 8 HIS A 216 LEU A 219 1 O MET A 218 N TYR A 189 +SHEET 5 AA2 8 ASN A 238 GLN A 243 1 O THR A 240 N LEU A 219 +SHEET 6 AA2 8 ILE A 355 MET A 360 -1 O ASP A 356 N GLN A 243 +SHEET 7 AA2 8 ARG A 366 ASN A 372 -1 O GLY A 369 N VAL A 357 +SHEET 8 AA2 8 ARG A 376 PRO A 379 -1 O VAL A 378 N TYR A 370 +SHEET 1 AA3 3 VAL A 335 GLY A 337 0 +SHEET 2 AA3 3 GLY A 340 PHE A 344 -1 O ILE A 342 N VAL A 335 +SHEET 3 AA3 3 ARG A 350 THR A 351 -1 O THR A 351 N GLN A 343 +SHEET 1 AA4 5 HIS B 42 HIS B 49 0 +SHEET 2 AA4 5 THR B 5 PHE B 12 1 N ILE B 6 O HIS B 42 +SHEET 3 AA4 5 ALA B 72 GLY B 75 1 O PHE B 74 N GLY B 9 +SHEET 4 AA4 5 PHE B 96 THR B 98 1 O VAL B 97 N ILE B 73 +SHEET 5 AA4 5 VAL B 110 GLN B 112 1 O ILE B 111 N PHE B 96 +SHEET 1 AA5 8 GLN B 159 SER B 164 0 +SHEET 2 AA5 8 LYS B 132 TYR B 137 1 N TYR B 135 O ARG B 163 +SHEET 3 AA5 8 ARG B 188 ASP B 192 1 O LEU B 190 N VAL B 134 +SHEET 4 AA5 8 HIS B 216 LEU B 219 1 O MET B 218 N TYR B 189 +SHEET 5 AA5 8 ASN B 238 GLN B 243 1 O THR B 240 N LEU B 219 +SHEET 6 AA5 8 THR B 354 MET B 360 -1 O ASP B 356 N GLN B 243 +SHEET 7 AA5 8 ARG B 366 ASN B 372 -1 O GLY B 369 N VAL B 357 +SHEET 8 AA5 8 ARG B 376 VAL B 378 -1 O VAL B 378 N TYR B 370 +SHEET 1 AA6 3 VAL B 335 GLY B 337 0 +SHEET 2 AA6 3 GLY B 340 PHE B 344 -1 O ILE B 342 N VAL B 335 +SHEET 3 AA6 3 ARG B 350 THR B 351 -1 O THR B 351 N GLN B 343 +SSBOND 1 CYS A 63 CYS A 312 1555 1555 2.05 +SSBOND 2 CYS B 63 CYS B 312 1555 1555 2.06 +LINK ND2 ASN B 352 C1 NAG B 401 1555 1555 1.37 +CRYST1 56.196 105.145 134.200 90.00 90.00 90.00 P 21 21 21 8 +ORIGX1 1.000000 0.000000 0.000000 0.00000 +ORIGX2 0.000000 1.000000 0.000000 0.00000 +ORIGX3 0.000000 0.000000 1.000000 0.00000 +SCALE1 0.017795 0.000000 0.000000 0.00000 +SCALE2 0.000000 0.009511 0.000000 0.00000 +SCALE3 0.000000 0.000000 0.007452 0.00000 +ATOM 1 N PHE A 2 18.180 51.053 34.125 1.00 45.35 N +ANISOU 1 N PHE A 2 8857 3476 4896 -714 -345 351 N +ATOM 2 CA PHE A 2 18.174 49.599 33.733 1.00 43.70 C +ANISOU 2 CA PHE A 2 8496 3486 4619 -664 -281 374 C +ATOM 3 C PHE A 2 19.246 49.327 32.667 1.00 43.81 C +ANISOU 3 C PHE A 2 8503 3614 4527 -812 -258 501 C +ATOM 4 O PHE A 2 19.359 50.093 31.704 1.00 45.19 O +ANISOU 4 O PHE A 2 8806 3680 4683 -889 -314 605 O +ATOM 5 CB PHE A 2 16.792 49.169 33.211 1.00 43.01 C +ANISOU 5 CB PHE A 2 8380 3361 4599 -480 -318 370 C +ATOM 6 CG PHE A 2 16.614 47.668 33.156 1.00 41.20 C +ANISOU 6 CG PHE A 2 7996 3337 4319 -409 -248 352 C +ATOM 7 CD1 PHE A 2 16.228 46.945 34.299 1.00 39.74 C +ANISOU 7 CD1 PHE A 2 7708 3232 4159 -327 -179 230 C +ATOM 8 CD2 PHE A 2 16.875 46.969 31.978 1.00 40.26 C +ANISOU 8 CD2 PHE A 2 7852 3326 4116 -439 -246 456 C +ATOM 9 CE1 PHE A 2 16.101 45.581 34.243 1.00 38.20 C +ANISOU 9 CE1 PHE A 2 7385 3210 3917 -274 -123 221 C +ATOM 10 CE2 PHE A 2 16.758 45.601 31.934 1.00 38.53 C +ANISOU 10 CE2 PHE A 2 7501 3283 3856 -379 -184 435 C +ATOM 11 CZ PHE A 2 16.366 44.907 33.061 1.00 37.69 C +ANISOU 11 CZ PHE A 2 7290 3244 3784 -294 -129 322 C +ATOM 12 N PRO A 3 20.037 48.249 32.832 1.00 42.90 N +ANISOU 12 N PRO A 3 8244 3709 4347 -858 -174 490 N +ATOM 13 CA PRO A 3 21.191 48.059 31.925 1.00 43.76 C +ANISOU 13 CA PRO A 3 8328 3925 4372 -1014 -123 586 C +ATOM 14 C PRO A 3 20.875 47.887 30.422 1.00 44.26 C +ANISOU 14 C PRO A 3 8458 3987 4369 -1015 -127 695 C +ATOM 15 O PRO A 3 19.797 47.444 30.064 1.00 43.14 O +ANISOU 15 O PRO A 3 8323 3826 4241 -871 -166 694 O +ATOM 16 CB PRO A 3 21.887 46.807 32.470 1.00 42.36 C +ANISOU 16 CB PRO A 3 7962 3960 4173 -1013 -43 532 C +ATOM 17 CG PRO A 3 20.942 46.193 33.430 1.00 41.10 C +ANISOU 17 CG PRO A 3 7749 3810 4055 -850 -55 433 C +ATOM 18 CD PRO A 3 20.022 47.264 33.922 1.00 41.54 C +ANISOU 18 CD PRO A 3 7936 3667 4179 -788 -122 387 C +ATOM 19 N ASN A 4 21.827 48.280 29.574 1.00 46.12 N +ANISOU 19 N ASN A 4 8752 4240 4531 -1193 -88 786 N +ATOM 20 CA ASN A 4 21.741 48.068 28.139 1.00 47.54 C +ANISOU 20 CA ASN A 4 9013 4439 4610 -1237 -70 890 C +ATOM 21 C ASN A 4 21.899 46.614 27.802 1.00 46.12 C +ANISOU 21 C ASN A 4 8680 4465 4378 -1183 28 862 C +ATOM 22 O ASN A 4 21.237 46.141 26.876 1.00 45.92 O +ANISOU 22 O ASN A 4 8710 4447 4288 -1122 11 907 O +ATOM 23 CB ASN A 4 22.813 48.865 27.380 1.00 50.46 C +ANISOU 23 CB ASN A 4 9488 4780 4902 -1471 -23 985 C +ATOM 24 CG ASN A 4 22.382 50.291 27.096 1.00 53.16 C +ANISOU 24 CG ASN A 4 10061 4879 5255 -1525 -149 1064 C +ATOM 25 OD1 ASN A 4 21.455 50.816 27.733 1.00 53.68 O +ANISOU 25 OD1 ASN A 4 10180 4792 5423 -1390 -266 1022 O +ATOM 26 ND2 ASN A 4 23.045 50.929 26.120 1.00 56.05 N +ANISOU 26 ND2 ASN A 4 10573 5201 5522 -1726 -121 1177 N +ATOM 27 N THR A 5 22.774 45.925 28.534 1.00 45.15 N +ANISOU 27 N THR A 5 8375 4494 4286 -1207 117 790 N +ATOM 28 CA THR A 5 23.012 44.510 28.317 1.00 44.40 C +ANISOU 28 CA THR A 5 8122 4584 4162 -1150 210 752 C +ATOM 29 C THR A 5 22.689 43.657 29.544 1.00 42.50 C +ANISOU 29 C THR A 5 7733 4413 3999 -1004 192 649 C +ATOM 30 O THR A 5 23.046 44.017 30.664 1.00 43.18 O +ANISOU 30 O THR A 5 7777 4479 4150 -1025 162 597 O +ATOM 31 CB THR A 5 24.469 44.261 27.886 1.00 45.76 C +ANISOU 31 CB THR A 5 8192 4890 4304 -1316 344 764 C +ATOM 32 OG1 THR A 5 24.775 45.107 26.773 1.00 47.84 O +ANISOU 32 OG1 THR A 5 8615 5083 4477 -1478 376 861 O +ATOM 33 CG2 THR A 5 24.668 42.819 27.428 1.00 45.22 C +ANISOU 33 CG2 THR A 5 7982 4992 4206 -1252 447 727 C +ATOM 34 N ILE A 6 21.989 42.547 29.317 1.00 40.39 N +ANISOU 34 N ILE A 6 7409 4220 3715 -870 204 623 N +ATOM 35 CA ILE A 6 21.789 41.527 30.321 1.00 38.49 C +ANISOU 35 CA ILE A 6 7029 4066 3525 -753 206 537 C +ATOM 36 C ILE A 6 22.575 40.271 29.908 1.00 38.23 C +ANISOU 36 C ILE A 6 6852 4204 3469 -762 303 523 C +ATOM 37 O ILE A 6 22.396 39.766 28.788 1.00 37.47 O +ANISOU 37 O ILE A 6 6782 4149 3306 -753 353 557 O +ATOM 38 CB ILE A 6 20.312 41.136 30.441 1.00 37.16 C +ANISOU 38 CB ILE A 6 6896 3846 3374 -587 147 509 C +ATOM 39 CG1 ILE A 6 19.470 42.321 30.882 1.00 37.47 C +ANISOU 39 CG1 ILE A 6 7056 3711 3470 -554 59 503 C +ATOM 40 CG2 ILE A 6 20.151 39.977 31.431 1.00 36.00 C +ANISOU 40 CG2 ILE A 6 6618 3798 3262 -488 165 427 C +ATOM 41 CD1 ILE A 6 19.830 42.885 32.234 1.00 37.73 C +ANISOU 41 CD1 ILE A 6 7076 3702 3556 -587 45 436 C +ATOM 42 N SER A 7 23.426 39.773 30.814 1.00 37.88 N +ANISOU 42 N SER A 7 6663 4246 3483 -778 320 470 N +ATOM 43 CA SER A 7 24.256 38.588 30.557 1.00 37.79 C +ANISOU 43 CA SER A 7 6490 4380 3487 -774 401 444 C +ATOM 44 C SER A 7 23.766 37.367 31.280 1.00 36.11 C +ANISOU 44 C SER A 7 6192 4223 3302 -632 369 387 C +ATOM 45 O SER A 7 23.421 37.436 32.461 1.00 35.87 O +ANISOU 45 O SER A 7 6169 4155 3305 -588 292 351 O +ATOM 46 CB SER A 7 25.701 38.844 30.962 1.00 39.13 C +ANISOU 46 CB SER A 7 6535 4606 3726 -900 429 433 C +ATOM 47 OG SER A 7 26.270 39.789 30.056 1.00 41.35 O +ANISOU 47 OG SER A 7 6880 4857 3971 -1053 495 489 O +ATOM 48 N ILE A 8 23.729 36.237 30.594 1.00 35.31 N +ANISOU 48 N ILE A 8 6026 4206 3181 -569 432 375 N +ATOM 49 CA ILE A 8 23.377 35.011 31.271 1.00 34.55 C +ANISOU 49 CA ILE A 8 5850 4160 3117 -447 400 325 C +ATOM 50 C ILE A 8 24.460 33.961 31.125 1.00 34.79 C +ANISOU 50 C ILE A 8 5713 4301 3205 -446 460 293 C +ATOM 51 O ILE A 8 25.328 34.054 30.258 1.00 35.97 O +ANISOU 51 O ILE A 8 5805 4500 3360 -526 557 300 O +ATOM 52 CB ILE A 8 21.996 34.476 30.831 1.00 34.04 C +ANISOU 52 CB ILE A 8 5869 4066 2997 -334 387 325 C +ATOM 53 CG1 ILE A 8 21.995 33.976 29.384 1.00 33.86 C +ANISOU 53 CG1 ILE A 8 5865 4088 2910 -337 469 346 C +ATOM 54 CG2 ILE A 8 20.929 35.539 31.049 1.00 34.05 C +ANISOU 54 CG2 ILE A 8 6008 3948 2982 -321 319 346 C +ATOM 55 CD1 ILE A 8 20.608 33.644 28.885 1.00 33.18 C +ANISOU 55 CD1 ILE A 8 5876 3958 2772 -245 428 356 C +ATOM 56 N GLY A 9 24.433 32.994 32.024 1.00 34.04 N +ANISOU 56 N GLY A 9 5538 4235 3159 -361 402 254 N +ATOM 57 CA GLY A 9 25.379 31.887 31.987 1.00 34.79 C +ANISOU 57 CA GLY A 9 5467 4415 3336 -331 432 219 C +ATOM 58 C GLY A 9 24.767 30.702 31.282 1.00 34.37 C +ANISOU 58 C GLY A 9 5417 4392 3248 -226 483 196 C +ATOM 59 O GLY A 9 23.556 30.566 31.224 1.00 32.40 O +ANISOU 59 O GLY A 9 5282 4100 2926 -163 455 206 O +ATOM 60 N GLY A 10 25.632 29.850 30.752 1.00 36.50 N +ANISOU 60 N GLY A 10 5552 4731 3583 -208 558 158 N +ATOM 61 CA GLY A 10 25.220 28.589 30.144 1.00 37.26 C +ANISOU 61 CA GLY A 10 5640 4854 3662 -108 605 122 C +ATOM 62 C GLY A 10 26.079 27.475 30.701 1.00 38.60 C +ANISOU 62 C GLY A 10 5638 5059 3966 -40 574 74 C +ATOM 63 O GLY A 10 27.294 27.529 30.561 1.00 40.34 O +ANISOU 63 O GLY A 10 5706 5325 4295 -85 625 47 O +ATOM 64 N LEU A 11 25.462 26.499 31.362 1.00 38.51 N +ANISOU 64 N LEU A 11 5648 5021 3961 61 483 66 N +ATOM 65 CA LEU A 11 26.150 25.264 31.752 1.00 39.90 C +ANISOU 65 CA LEU A 11 5685 5211 4262 144 440 24 C +ATOM 66 C LEU A 11 25.625 24.077 30.970 1.00 39.30 C +ANISOU 66 C LEU A 11 5634 5137 4159 237 504 -16 C +ATOM 67 O LEU A 11 24.508 23.647 31.185 1.00 37.01 O +ANISOU 67 O LEU A 11 5464 4809 3789 286 452 0 O +ATOM 68 CB LEU A 11 25.957 24.985 33.242 1.00 40.34 C +ANISOU 68 CB LEU A 11 5762 5221 4345 174 265 54 C +ATOM 69 CG LEU A 11 26.621 26.003 34.155 1.00 41.67 C +ANISOU 69 CG LEU A 11 5899 5381 4551 82 178 84 C +ATOM 70 CD1 LEU A 11 26.543 25.550 35.582 1.00 41.74 C +ANISOU 70 CD1 LEU A 11 5941 5343 4574 105 3 107 C +ATOM 71 CD2 LEU A 11 28.074 26.201 33.746 1.00 43.92 C +ANISOU 71 CD2 LEU A 11 5988 5716 4981 37 227 55 C +ATOM 72 N PHE A 12 26.460 23.535 30.095 1.00 41.34 N +ANISOU 72 N PHE A 12 5775 5437 4495 257 620 -78 N +ATOM 73 CA PHE A 12 26.085 22.411 29.220 1.00 42.15 C +ANISOU 73 CA PHE A 12 5904 5538 4571 337 700 -135 C +ATOM 74 C PHE A 12 26.880 21.168 29.558 1.00 44.83 C +ANISOU 74 C PHE A 12 6086 5865 5082 441 665 -195 C +ATOM 75 O PHE A 12 28.020 21.252 30.012 1.00 46.30 O +ANISOU 75 O PHE A 12 6098 6066 5426 438 637 -213 O +ATOM 76 CB PHE A 12 26.282 22.808 27.752 1.00 41.89 C +ANISOU 76 CB PHE A 12 5902 5554 4458 268 891 -172 C +ATOM 77 CG PHE A 12 25.326 23.864 27.302 1.00 40.62 C +ANISOU 77 CG PHE A 12 5927 5382 4122 183 899 -105 C +ATOM 78 CD1 PHE A 12 25.598 25.202 27.521 1.00 40.61 C +ANISOU 78 CD1 PHE A 12 5941 5387 4102 77 892 -51 C +ATOM 79 CD2 PHE A 12 24.115 23.519 26.744 1.00 39.82 C +ANISOU 79 CD2 PHE A 12 5986 5251 3890 214 888 -94 C +ATOM 80 CE1 PHE A 12 24.699 26.183 27.154 1.00 39.71 C +ANISOU 80 CE1 PHE A 12 5998 5240 3846 12 876 12 C +ATOM 81 CE2 PHE A 12 23.201 24.501 26.376 1.00 39.31 C +ANISOU 81 CE2 PHE A 12 6082 5161 3691 149 864 -28 C +ATOM 82 CZ PHE A 12 23.493 25.833 26.593 1.00 39.10 C +ANISOU 82 CZ PHE A 12 6069 5132 3653 53 856 25 C +ATOM 83 N MET A 13 26.258 20.012 29.363 1.00 47.15 N +ANISOU 83 N MET A 13 6441 6119 5355 534 650 -225 N +ATOM 84 CA MET A 13 26.855 18.717 29.699 1.00 50.44 C +ANISOU 84 CA MET A 13 6735 6494 5934 649 594 -279 C +ATOM 85 C MET A 13 27.252 17.971 28.449 1.00 51.92 C +ANISOU 85 C MET A 13 6868 6699 6160 697 767 -387 C +ATOM 86 O MET A 13 27.098 18.478 27.350 1.00 52.61 O +ANISOU 86 O MET A 13 7020 6836 6131 626 929 -414 O +ATOM 87 CB MET A 13 25.843 17.836 30.427 1.00 51.47 C +ANISOU 87 CB MET A 13 6991 6550 6015 717 450 -239 C +ATOM 88 CG MET A 13 25.413 18.328 31.773 1.00 52.51 C +ANISOU 88 CG MET A 13 7193 6652 6106 676 284 -148 C +ATOM 89 SD MET A 13 24.223 17.149 32.424 1.00 57.14 S +ANISOU 89 SD MET A 13 7929 7153 6626 739 163 -116 S +ATOM 90 CE MET A 13 25.382 15.889 33.030 1.00 57.55 C +ANISOU 90 CE MET A 13 7836 7136 6894 848 37 -144 C +ATOM 91 N ARG A 14 27.754 16.749 28.639 1.00 52.94 N +ANISOU 91 N ARG A 14 6889 6775 6448 815 727 -449 N +ATOM 92 CA ARG A 14 27.906 15.777 27.574 1.00 53.32 C +ANISOU 92 CA ARG A 14 6921 6811 6528 884 872 -563 C +ATOM 93 C ARG A 14 26.554 15.519 26.870 1.00 51.74 C +ANISOU 93 C ARG A 14 6954 6596 6109 864 910 -553 C +ATOM 94 O ARG A 14 25.505 15.433 27.524 1.00 50.13 O +ANISOU 94 O ARG A 14 6885 6350 5811 865 768 -471 O +ATOM 95 CB ARG A 14 28.447 14.477 28.171 1.00 54.44 C +ANISOU 95 CB ARG A 14 6939 6864 6880 1028 759 -610 C +ATOM 96 N ASN A 15 26.585 15.428 25.544 1.00 51.74 N +ANISOU 96 N ASN A 15 7000 6630 6026 835 1103 -638 N +ATOM 97 CA ASN A 15 25.386 15.121 24.751 1.00 51.53 C +ANISOU 97 CA ASN A 15 7191 6587 5802 813 1132 -639 C +ATOM 98 C ASN A 15 24.264 16.147 24.906 1.00 48.17 C +ANISOU 98 C ASN A 15 6928 6181 5192 717 1051 -522 C +ATOM 99 O ASN A 15 23.121 15.786 25.144 1.00 45.90 O +ANISOU 99 O ASN A 15 6769 5847 4820 734 943 -476 O +ATOM 100 CB ASN A 15 24.831 13.703 25.054 1.00 53.63 C +ANISOU 100 CB ASN A 15 7506 6756 6112 926 1028 -668 C +ATOM 101 CG ASN A 15 23.700 13.288 24.077 1.00 54.72 C +ANISOU 101 CG ASN A 15 7854 6876 6062 897 1071 -691 C +ATOM 102 OD1 ASN A 15 23.866 13.329 22.842 1.00 56.96 O +ANISOU 102 OD1 ASN A 15 8195 7194 6251 852 1241 -771 O +ATOM 103 ND2 ASN A 15 22.545 12.910 24.630 1.00 52.89 N +ANISOU 103 ND2 ASN A 15 7738 6589 5767 911 918 -621 N +ATOM 104 N THR A 16 24.604 17.425 24.755 1.00 46.36 N +ANISOU 104 N THR A 16 6684 6014 4915 615 1108 -478 N +ATOM 105 CA THR A 16 23.624 18.502 24.741 1.00 43.78 C +ANISOU 105 CA THR A 16 6507 5698 4428 525 1049 -379 C +ATOM 106 C THR A 16 23.962 19.456 23.588 1.00 42.89 C +ANISOU 106 C THR A 16 6455 5643 4197 405 1206 -387 C +ATOM 107 O THR A 16 23.769 20.656 23.680 1.00 41.65 O +ANISOU 107 O THR A 16 6351 5501 3971 317 1179 -308 O +ATOM 108 CB THR A 16 23.579 19.288 26.090 1.00 43.87 C +ANISOU 108 CB THR A 16 6466 5701 4499 512 905 -287 C +ATOM 109 OG1 THR A 16 24.863 19.871 26.364 1.00 45.26 O +ANISOU 109 OG1 THR A 16 6483 5920 4793 476 956 -299 O +ATOM 110 CG2 THR A 16 23.143 18.392 27.272 1.00 43.67 C +ANISOU 110 CG2 THR A 16 6424 5614 4553 605 746 -265 C +ATOM 111 N VAL A 17 24.469 18.898 22.502 1.00 42.87 N +ANISOU 111 N VAL A 17 6457 5663 4168 396 1374 -486 N +ATOM 112 CA VAL A 17 24.885 19.671 21.335 1.00 43.34 C +ANISOU 112 CA VAL A 17 6589 5776 4099 266 1550 -506 C +ATOM 113 C VAL A 17 23.701 20.392 20.676 1.00 41.69 C +ANISOU 113 C VAL A 17 6626 5550 3664 176 1490 -418 C +ATOM 114 O VAL A 17 23.806 21.570 20.382 1.00 41.72 O +ANISOU 114 O VAL A 17 6693 5575 3582 60 1519 -353 O +ATOM 115 CB VAL A 17 25.587 18.749 20.297 1.00 45.29 C +ANISOU 115 CB VAL A 17 6811 6045 4352 279 1759 -653 C +ATOM 116 CG1 VAL A 17 25.801 19.476 19.005 1.00 46.56 C +ANISOU 116 CG1 VAL A 17 7110 6255 4325 122 1943 -669 C +ATOM 117 CG2 VAL A 17 26.918 18.225 20.836 1.00 46.57 C +ANISOU 117 CG2 VAL A 17 6699 6224 4769 359 1834 -746 C +ATOM 118 N GLN A 18 22.583 19.699 20.452 1.00 40.24 N +ANISOU 118 N GLN A 18 6576 5317 3395 226 1394 -414 N +ATOM 119 CA GLN A 18 21.420 20.332 19.841 1.00 39.32 C +ANISOU 119 CA GLN A 18 6674 5173 3092 152 1307 -331 C +ATOM 120 C GLN A 18 20.885 21.477 20.725 1.00 37.05 C +ANISOU 120 C GLN A 18 6380 4863 2831 135 1156 -210 C +ATOM 121 O GLN A 18 20.572 22.578 20.242 1.00 36.28 O +ANISOU 121 O GLN A 18 6405 4757 2619 37 1135 -134 O +ATOM 122 CB GLN A 18 20.294 19.325 19.592 1.00 38.97 C +ANISOU 122 CB GLN A 18 6740 5076 2989 216 1207 -350 C +ATOM 123 CG GLN A 18 19.272 19.848 18.574 1.00 39.72 C +ANISOU 123 CG GLN A 18 7067 5146 2879 124 1142 -290 C +ATOM 124 CD GLN A 18 18.042 18.975 18.466 1.00 39.63 C +ANISOU 124 CD GLN A 18 7146 5079 2831 179 1006 -294 C +ATOM 125 OE1 GLN A 18 17.180 18.994 19.347 1.00 38.38 O +ANISOU 125 OE1 GLN A 18 6940 4885 2755 239 849 -236 O +ATOM 126 NE2 GLN A 18 17.943 18.217 17.356 1.00 40.83 N +ANISOU 126 NE2 GLN A 18 7436 5223 2854 147 1072 -368 N +ATOM 127 N GLU A 19 20.778 21.185 22.010 1.00 35.13 N +ANISOU 127 N GLU A 19 6007 4602 2737 228 1050 -196 N +ATOM 128 CA GLU A 19 20.324 22.162 23.006 1.00 33.91 C +ANISOU 128 CA GLU A 19 5834 4424 2625 222 923 -105 C +ATOM 129 C GLU A 19 21.210 23.401 23.056 1.00 33.72 C +ANISOU 129 C GLU A 19 5769 4431 2612 129 986 -68 C +ATOM 130 O GLU A 19 20.708 24.516 23.147 1.00 32.49 O +ANISOU 130 O GLU A 19 5695 4244 2405 73 916 10 O +ATOM 131 CB GLU A 19 20.244 21.524 24.386 1.00 33.13 C +ANISOU 131 CB GLU A 19 5613 4305 2669 321 826 -110 C +ATOM 132 CG GLU A 19 19.211 20.428 24.488 1.00 32.91 C +ANISOU 132 CG GLU A 19 5636 4234 2631 397 744 -128 C +ATOM 133 CD GLU A 19 19.762 19.011 24.226 1.00 34.58 C +ANISOU 133 CD GLU A 19 5793 4446 2898 466 809 -220 C +ATOM 134 OE1 GLU A 19 20.639 18.781 23.323 1.00 35.82 O +ANISOU 134 OE1 GLU A 19 5933 4637 3039 445 950 -290 O +ATOM 135 OE2 GLU A 19 19.287 18.105 24.956 1.00 35.26 O +ANISOU 135 OE2 GLU A 19 5858 4491 3047 540 721 -227 O +ATOM 136 N HIS A 20 22.517 23.187 22.942 1.00 34.74 N +ANISOU 136 N HIS A 20 5770 4612 2816 110 1121 -131 N +ATOM 137 CA HIS A 20 23.461 24.278 22.783 1.00 35.96 C +ANISOU 137 CA HIS A 20 5883 4803 2976 -1 1212 -110 C +ATOM 138 C HIS A 20 23.110 25.120 21.541 1.00 36.14 C +ANISOU 138 C HIS A 20 6106 4819 2806 -128 1272 -63 C +ATOM 139 O HIS A 20 23.059 26.349 21.608 1.00 36.11 O +ANISOU 139 O HIS A 20 6164 4792 2761 -216 1234 16 O +ATOM 140 CB HIS A 20 24.910 23.745 22.757 1.00 37.90 C +ANISOU 140 CB HIS A 20 5932 5109 3357 4 1361 -205 C +ATOM 141 CG HIS A 20 25.952 24.801 22.554 1.00 40.13 C +ANISOU 141 CG HIS A 20 6150 5436 3660 -124 1473 -193 C +ATOM 142 ND1 HIS A 20 26.499 25.524 23.595 1.00 40.50 N +ANISOU 142 ND1 HIS A 20 6071 5485 3832 -145 1398 -151 N +ATOM 143 CD2 HIS A 20 26.546 25.259 21.423 1.00 42.10 C +ANISOU 143 CD2 HIS A 20 6453 5728 3814 -256 1660 -218 C +ATOM 144 CE1 HIS A 20 27.383 26.383 23.111 1.00 42.18 C +ANISOU 144 CE1 HIS A 20 6250 5738 4037 -281 1528 -149 C +ATOM 145 NE2 HIS A 20 27.435 26.236 21.798 1.00 42.98 N +ANISOU 145 NE2 HIS A 20 6457 5866 4005 -353 1696 -189 N +ATOM 146 N SER A 21 22.820 24.463 20.426 1.00 36.42 N +ANISOU 146 N SER A 21 6261 4859 2715 -142 1348 -108 N +ATOM 147 CA SER A 21 22.430 25.180 19.211 1.00 36.75 C +ANISOU 147 CA SER A 21 6528 4885 2550 -271 1382 -57 C +ATOM 148 C SER A 21 21.125 25.918 19.387 1.00 35.25 C +ANISOU 148 C SER A 21 6481 4615 2294 -265 1177 55 C +ATOM 149 O SER A 21 21.023 27.089 18.998 1.00 35.46 O +ANISOU 149 O SER A 21 6634 4609 2230 -373 1151 140 O +ATOM 150 CB SER A 21 22.341 24.240 18.031 1.00 37.75 C +ANISOU 150 CB SER A 21 6771 5027 2543 -288 1492 -136 C +ATOM 151 OG SER A 21 23.647 23.865 17.673 1.00 39.75 O +ANISOU 151 OG SER A 21 6908 5351 2844 -327 1720 -242 O +ATOM 152 N ALA A 22 20.131 25.244 19.972 1.00 33.55 N +ANISOU 152 N ALA A 22 6245 4362 2137 -143 1034 54 N +ATOM 153 CA ALA A 22 18.840 25.872 20.227 1.00 32.51 C +ANISOU 153 CA ALA A 22 6211 4155 1987 -120 843 143 C +ATOM 154 C ALA A 22 18.988 27.075 21.155 1.00 32.25 C +ANISOU 154 C ALA A 22 6116 4093 2042 -136 783 208 C +ATOM 155 O ALA A 22 18.282 28.077 20.982 1.00 32.41 O +ANISOU 155 O ALA A 22 6253 4043 2016 -173 675 290 O +ATOM 156 CB ALA A 22 17.882 24.892 20.832 1.00 31.22 C +ANISOU 156 CB ALA A 22 5995 3968 1898 5 732 115 C +ATOM 157 N PHE A 23 19.914 26.983 22.109 1.00 31.70 N +ANISOU 157 N PHE A 23 5872 4068 2104 -110 844 169 N +ATOM 158 CA PHE A 23 20.169 28.073 23.036 1.00 31.51 C +ANISOU 158 CA PHE A 23 5792 4018 2161 -136 794 218 C +ATOM 159 C PHE A 23 20.728 29.281 22.302 1.00 33.22 C +ANISOU 159 C PHE A 23 6107 4222 2290 -280 855 274 C +ATOM 160 O PHE A 23 20.221 30.388 22.433 1.00 32.83 O +ANISOU 160 O PHE A 23 6150 4099 2223 -316 758 350 O +ATOM 161 CB PHE A 23 21.133 27.610 24.141 1.00 30.94 C +ANISOU 161 CB PHE A 23 5519 3997 2239 -90 834 163 C +ATOM 162 CG PHE A 23 21.581 28.693 25.088 1.00 30.57 C +ANISOU 162 CG PHE A 23 5416 3930 2269 -134 791 201 C +ATOM 163 CD1 PHE A 23 20.794 29.055 26.151 1.00 29.44 C +ANISOU 163 CD1 PHE A 23 5279 3730 2177 -79 662 228 C +ATOM 164 CD2 PHE A 23 22.817 29.291 24.939 1.00 31.44 C +ANISOU 164 CD2 PHE A 23 5460 4080 2405 -237 891 199 C +ATOM 165 CE1 PHE A 23 21.220 30.023 27.044 1.00 29.53 C +ANISOU 165 CE1 PHE A 23 5253 3716 2250 -124 625 252 C +ATOM 166 CE2 PHE A 23 23.241 30.254 25.819 1.00 31.52 C +ANISOU 166 CE2 PHE A 23 5422 4066 2485 -286 842 231 C +ATOM 167 CZ PHE A 23 22.453 30.616 26.881 1.00 30.36 C +ANISOU 167 CZ PHE A 23 5300 3856 2377 -228 705 256 C +ATOM 168 N ARG A 24 21.766 29.062 21.516 1.00 35.22 N +ANISOU 168 N ARG A 24 6346 4541 2492 -366 1023 234 N +ATOM 169 CA ARG A 24 22.371 30.156 20.767 1.00 37.38 C +ANISOU 169 CA ARG A 24 6723 4808 2668 -529 1106 286 C +ATOM 170 C ARG A 24 21.385 30.781 19.779 1.00 37.45 C +ANISOU 170 C ARG A 24 6987 4736 2503 -591 1015 374 C +ATOM 171 O ARG A 24 21.336 31.986 19.620 1.00 38.20 O +ANISOU 171 O ARG A 24 7196 4766 2551 -686 965 460 O +ATOM 172 CB ARG A 24 23.626 29.670 20.061 1.00 39.90 C +ANISOU 172 CB ARG A 24 6971 5221 2966 -612 1331 207 C +ATOM 173 CG ARG A 24 24.738 29.404 21.063 1.00 40.87 C +ANISOU 173 CG ARG A 24 6832 5406 3289 -574 1394 141 C +ATOM 174 CD ARG A 24 26.023 28.968 20.389 1.00 44.25 C +ANISOU 174 CD ARG A 24 7150 5924 3736 -651 1628 49 C +ATOM 175 NE ARG A 24 26.534 29.936 19.412 1.00 47.39 N +ANISOU 175 NE ARG A 24 7676 6331 3999 -848 1765 88 N +ATOM 176 CZ ARG A 24 27.165 29.609 18.279 1.00 50.44 C +ANISOU 176 CZ ARG A 24 8102 6776 4284 -952 1986 21 C +ATOM 177 NH1 ARG A 24 27.366 28.332 17.948 1.00 51.45 N +ANISOU 177 NH1 ARG A 24 8148 6955 4442 -865 2096 -96 N +ATOM 178 NH2 ARG A 24 27.581 30.570 17.461 1.00 52.69 N +ANISOU 178 NH2 ARG A 24 8527 7061 4431 -1151 2103 71 N +ATOM 179 N PHE A 25 20.571 29.953 19.160 1.00 36.79 N +ANISOU 179 N PHE A 25 6997 4645 2336 -535 971 356 N +ATOM 180 CA PHE A 25 19.615 30.417 18.176 1.00 37.27 C +ANISOU 180 CA PHE A 25 7300 4626 2235 -591 858 438 C +ATOM 181 C PHE A 25 18.462 31.184 18.792 1.00 35.98 C +ANISOU 181 C PHE A 25 7170 4353 2145 -517 635 519 C +ATOM 182 O PHE A 25 18.013 32.174 18.228 1.00 36.95 O +ANISOU 182 O PHE A 25 7470 4385 2182 -592 532 616 O +ATOM 183 CB PHE A 25 19.086 29.238 17.359 1.00 37.50 C +ANISOU 183 CB PHE A 25 7410 4677 2159 -555 865 385 C +ATOM 184 CG PHE A 25 18.108 29.628 16.294 1.00 38.48 C +ANISOU 184 CG PHE A 25 7792 4718 2109 -619 725 471 C +ATOM 185 CD1 PHE A 25 18.456 30.513 15.294 1.00 40.38 C +ANISOU 185 CD1 PHE A 25 8245 4926 2170 -790 764 545 C +ATOM 186 CD2 PHE A 25 16.836 29.095 16.279 1.00 37.94 C +ANISOU 186 CD2 PHE A 25 7760 4598 2056 -517 546 480 C +ATOM 187 CE1 PHE A 25 17.553 30.862 14.293 1.00 41.48 C +ANISOU 187 CE1 PHE A 25 8644 4976 2140 -855 605 635 C +ATOM 188 CE2 PHE A 25 15.926 29.437 15.279 1.00 39.02 C +ANISOU 188 CE2 PHE A 25 8130 4650 2043 -576 387 562 C +ATOM 189 CZ PHE A 25 16.286 30.331 14.292 1.00 40.72 C +ANISOU 189 CZ PHE A 25 8570 4826 2073 -742 406 644 C +ATOM 190 N ALA A 26 17.974 30.744 19.940 1.00 34.11 N +ANISOU 190 N ALA A 26 6772 4117 2071 -375 560 479 N +ATOM 191 CA ALA A 26 16.864 31.423 20.614 1.00 33.17 C +ANISOU 191 CA ALA A 26 6658 3897 2045 -296 376 531 C +ATOM 192 C ALA A 26 17.261 32.822 21.086 1.00 33.69 C +ANISOU 192 C ALA A 26 6740 3901 2158 -359 355 590 C +ATOM 193 O ALA A 26 16.437 33.746 21.082 1.00 33.82 O +ANISOU 193 O ALA A 26 6850 3803 2196 -347 208 658 O +ATOM 194 CB ALA A 26 16.411 30.610 21.791 1.00 31.68 C +ANISOU 194 CB ALA A 26 6294 3736 2006 -156 345 463 C +ATOM 195 N VAL A 27 18.522 32.965 21.504 1.00 33.69 N +ANISOU 195 N VAL A 27 6640 3969 2190 -424 495 558 N +ATOM 196 CA VAL A 27 19.045 34.236 21.961 1.00 34.27 C +ANISOU 196 CA VAL A 27 6724 3990 2306 -501 489 605 C +ATOM 197 C VAL A 27 19.141 35.190 20.778 1.00 36.51 C +ANISOU 197 C VAL A 27 7224 4205 2441 -648 480 700 C +ATOM 198 O VAL A 27 18.812 36.380 20.874 1.00 36.98 O +ANISOU 198 O VAL A 27 7386 4149 2515 -684 372 776 O +ATOM 199 CB VAL A 27 20.431 34.047 22.636 1.00 34.08 C +ANISOU 199 CB VAL A 27 6526 4064 2358 -546 635 545 C +ATOM 200 CG1 VAL A 27 21.131 35.381 22.868 1.00 34.73 C +ANISOU 200 CG1 VAL A 27 6640 4096 2458 -668 646 597 C +ATOM 201 CG2 VAL A 27 20.265 33.301 23.958 1.00 32.57 C +ANISOU 201 CG2 VAL A 27 6154 3908 2311 -409 599 473 C +ATOM 202 N GLN A 28 19.602 34.647 19.660 1.00 37.93 N +ANISOU 202 N GLN A 28 7486 4451 2473 -738 597 692 N +ATOM 203 CA GLN A 28 19.690 35.378 18.412 1.00 40.29 C +ANISOU 203 CA GLN A 28 8024 4693 2588 -897 601 782 C +ATOM 204 C GLN A 28 18.316 35.853 17.930 1.00 40.74 C +ANISOU 204 C GLN A 28 8272 4612 2594 -855 371 874 C +ATOM 205 O GLN A 28 18.219 36.953 17.405 1.00 42.28 O +ANISOU 205 O GLN A 28 8656 4698 2710 -960 289 979 O +ATOM 206 CB GLN A 28 20.345 34.493 17.365 1.00 41.53 C +ANISOU 206 CB GLN A 28 8230 4957 2593 -987 785 729 C +ATOM 207 CG GLN A 28 20.466 35.087 15.991 1.00 44.00 C +ANISOU 207 CG GLN A 28 8818 5224 2673 -1175 816 813 C +ATOM 208 CD GLN A 28 21.215 34.158 15.060 1.00 45.56 C +ANISOU 208 CD GLN A 28 9044 5538 2726 -1267 1042 731 C +ATOM 209 OE1 GLN A 28 20.835 33.994 13.893 1.00 47.27 O +ANISOU 209 OE1 GLN A 28 9497 5731 2732 -1354 1031 766 O +ATOM 210 NE2 GLN A 28 22.304 33.555 15.563 1.00 45.30 N +ANISOU 210 NE2 GLN A 28 8774 5627 2808 -1252 1248 618 N +ATOM 211 N LEU A 29 17.270 35.036 18.100 1.00 39.49 N +ANISOU 211 N LEU A 29 8063 4449 2490 -707 258 839 N +ATOM 212 CA LEU A 29 15.878 35.460 17.829 1.00 39.49 C +ANISOU 212 CA LEU A 29 8187 4314 2505 -638 15 914 C +ATOM 213 C LEU A 29 15.386 36.548 18.796 1.00 38.55 C +ANISOU 213 C LEU A 29 8012 4075 2560 -564 -117 949 C +ATOM 214 O LEU A 29 14.631 37.421 18.432 1.00 39.68 O +ANISOU 214 O LEU A 29 8295 4074 2706 -564 -298 1037 O +ATOM 215 CB LEU A 29 14.916 34.269 17.865 1.00 38.62 C +ANISOU 215 CB LEU A 29 7999 4236 2436 -503 -57 854 C +ATOM 216 CG LEU A 29 15.096 33.265 16.728 1.00 39.86 C +ANISOU 216 CG LEU A 29 8269 4470 2406 -571 19 829 C +ATOM 217 CD1 LEU A 29 14.222 32.045 16.946 1.00 38.90 C +ANISOU 217 CD1 LEU A 29 8043 4383 2353 -436 -43 757 C +ATOM 218 CD2 LEU A 29 14.769 33.889 15.371 1.00 42.09 C +ANISOU 218 CD2 LEU A 29 8845 4658 2486 -703 -95 941 C +ATOM 219 N TYR A 30 15.809 36.499 20.032 1.00 37.06 N +ANISOU 219 N TYR A 30 7626 3937 2518 -499 -34 875 N +ATOM 220 CA TYR A 30 15.488 37.573 20.961 1.00 36.51 C +ANISOU 220 CA TYR A 30 7519 3755 2597 -449 -127 892 C +ATOM 221 C TYR A 30 16.122 38.887 20.439 1.00 38.65 C +ANISOU 221 C TYR A 30 7964 3933 2786 -605 -136 990 C +ATOM 222 O TYR A 30 15.453 39.921 20.367 1.00 39.39 O +ANISOU 222 O TYR A 30 8171 3866 2927 -590 -299 1062 O +ATOM 223 CB TYR A 30 15.914 37.231 22.407 1.00 34.25 C +ANISOU 223 CB TYR A 30 7012 3546 2454 -374 -30 791 C +ATOM 224 CG TYR A 30 15.830 38.431 23.258 1.00 34.02 C +ANISOU 224 CG TYR A 30 6980 3405 2540 -364 -93 804 C +ATOM 225 CD1 TYR A 30 14.612 38.880 23.705 1.00 33.72 C +ANISOU 225 CD1 TYR A 30 6938 3245 2628 -244 -239 799 C +ATOM 226 CD2 TYR A 30 16.952 39.199 23.521 1.00 34.44 C +ANISOU 226 CD2 TYR A 30 7046 3460 2577 -484 -9 820 C +ATOM 227 CE1 TYR A 30 14.506 40.056 24.406 1.00 34.16 C +ANISOU 227 CE1 TYR A 30 7013 3176 2788 -235 -295 803 C +ATOM 228 CE2 TYR A 30 16.850 40.383 24.220 1.00 34.78 C +ANISOU 228 CE2 TYR A 30 7118 3379 2715 -486 -79 834 C +ATOM 229 CZ TYR A 30 15.624 40.803 24.648 1.00 34.70 C +ANISOU 229 CZ TYR A 30 7117 3242 2824 -358 -219 823 C +ATOM 230 OH TYR A 30 15.519 41.991 25.334 1.00 35.69 O +ANISOU 230 OH TYR A 30 7278 3232 3050 -356 -279 823 O +ATOM 231 N ASN A 31 17.393 38.822 20.043 1.00 39.89 N +ANISOU 231 N ASN A 31 8140 4185 2828 -755 39 990 N +ATOM 232 CA ASN A 31 18.177 40.011 19.683 1.00 41.94 C +ANISOU 232 CA ASN A 31 8541 4377 3018 -927 70 1072 C +ATOM 233 C ASN A 31 17.889 40.596 18.292 1.00 44.91 C +ANISOU 233 C ASN A 31 9204 4649 3208 -1055 -19 1198 C +ATOM 234 O ASN A 31 18.175 41.755 18.056 1.00 46.71 O +ANISOU 234 O ASN A 31 9583 4764 3398 -1176 -62 1287 O +ATOM 235 CB ASN A 31 19.679 39.722 19.789 1.00 41.84 C +ANISOU 235 CB ASN A 31 8418 4509 2969 -1053 306 1018 C +ATOM 236 CG ASN A 31 20.173 39.729 21.216 1.00 40.62 C +ANISOU 236 CG ASN A 31 8037 4401 2994 -985 351 936 C +ATOM 237 OD1 ASN A 31 19.727 40.551 22.025 1.00 40.48 O +ANISOU 237 OD1 ASN A 31 8018 4272 3090 -929 233 949 O +ATOM 238 ND2 ASN A 31 21.086 38.798 21.549 1.00 39.80 N +ANISOU 238 ND2 ASN A 31 7745 4453 2922 -986 515 845 N +ATOM 239 N THR A 32 17.342 39.807 17.374 1.00 46.35 N +ANISOU 239 N THR A 32 9480 4861 3267 -1041 -56 1209 N +ATOM 240 CA THR A 32 17.076 40.268 16.036 1.00 49.63 C +ANISOU 240 CA THR A 32 10192 5183 3481 -1175 -152 1329 C +ATOM 241 C THR A 32 15.589 40.526 15.799 1.00 51.33 C +ANISOU 241 C THR A 32 10511 5241 3751 -1052 -445 1399 C +ATOM 242 O THR A 32 15.141 40.621 14.652 1.00 53.62 O +ANISOU 242 O THR A 32 11042 5457 3872 -1132 -571 1494 O +ATOM 243 CB THR A 32 17.538 39.234 14.997 1.00 50.43 C +ANISOU 243 CB THR A 32 10371 5418 3370 -1277 5 1296 C +ATOM 244 OG1 THR A 32 16.815 38.013 15.210 1.00 49.31 O +ANISOU 244 OG1 THR A 32 10093 5348 3294 -1110 -30 1208 O +ATOM 245 CG2 THR A 32 19.047 39.010 15.089 1.00 50.38 C +ANISOU 245 CG2 THR A 32 10260 5560 3321 -1409 304 1224 C +ATOM 246 N ASN A 33 14.822 40.646 16.867 1.00 51.54 N +ANISOU 246 N ASN A 33 10358 5211 4012 -865 -558 1350 N +ATOM 247 CA ASN A 33 13.401 40.901 16.753 1.00 53.23 C +ANISOU 247 CA ASN A 33 10618 5275 4331 -732 -828 1398 C +ATOM 248 C ASN A 33 13.170 42.281 16.178 1.00 56.45 C +ANISOU 248 C ASN A 33 11269 5474 4703 -815 -1019 1542 C +ATOM 249 O ASN A 33 13.702 43.269 16.658 1.00 55.97 O +ANISOU 249 O ASN A 33 11225 5340 4699 -868 -987 1566 O +ATOM 250 CB ASN A 33 12.710 40.764 18.126 1.00 51.73 C +ANISOU 250 CB ASN A 33 10163 5077 4413 -524 -862 1293 C +ATOM 251 CG ASN A 33 11.201 40.749 18.027 1.00 51.89 C +ANISOU 251 CG ASN A 33 10168 4976 4571 -370 -1109 1310 C +ATOM 252 OD1 ASN A 33 10.626 41.148 17.021 1.00 55.64 O +ANISOU 252 OD1 ASN A 33 10842 5327 4972 -409 -1310 1420 O +ATOM 253 ND2 ASN A 33 10.557 40.304 19.064 1.00 50.17 N +ANISOU 253 ND2 ASN A 33 9716 4787 4557 -204 -1100 1202 N +ATOM 254 N GLN A 34 12.343 42.303 15.142 1.00 60.71 N +ANISOU 254 N GLN A 34 12004 5911 5150 -828 -1234 1639 N +ATOM 255 CA GLN A 34 11.948 43.501 14.423 1.00 65.17 C +ANISOU 255 CA GLN A 34 12836 6255 5668 -900 -1473 1795 C +ATOM 256 C GLN A 34 11.142 44.467 15.301 1.00 67.11 C +ANISOU 256 C GLN A 34 12979 6314 6204 -732 -1660 1795 C +ATOM 257 O GLN A 34 11.008 45.641 14.965 1.00 70.05 O +ANISOU 257 O GLN A 34 13546 6486 6583 -786 -1833 1914 O +ATOM 258 CB GLN A 34 11.116 43.058 13.225 1.00 67.55 C +ANISOU 258 CB GLN A 34 13330 6505 5829 -920 -1683 1879 C +ATOM 259 CG GLN A 34 10.758 44.127 12.199 1.00 71.17 C +ANISOU 259 CG GLN A 34 14130 6740 6171 -1032 -1953 2065 C +ATOM 260 CD GLN A 34 10.119 43.518 10.960 1.00 73.01 C +ANISOU 260 CD GLN A 34 14572 6957 6209 -1089 -2133 2140 C +ATOM 261 OE1 GLN A 34 9.239 44.121 10.333 1.00 76.06 O +ANISOU 261 OE1 GLN A 34 15146 7142 6609 -1073 -2463 2269 O +ATOM 262 NE2 GLN A 34 10.545 42.302 10.613 1.00 72.06 N +ANISOU 262 NE2 GLN A 34 14421 7041 5915 -1150 -1930 2056 N +ATOM 263 N ASN A 35 10.601 43.961 16.411 1.00 66.58 N +ANISOU 263 N ASN A 35 12616 6306 6373 -535 -1621 1659 N +ATOM 264 CA ASN A 35 9.867 44.762 17.389 1.00 66.90 C +ANISOU 264 CA ASN A 35 12521 6194 6703 -366 -1741 1617 C +ATOM 265 C ASN A 35 10.810 45.265 18.479 1.00 65.81 C +ANISOU 265 C ASN A 35 12278 6096 6629 -397 -1535 1543 C +ATOM 266 O ASN A 35 11.381 44.479 19.217 1.00 65.41 O +ANISOU 266 O ASN A 35 12040 6231 6579 -385 -1314 1428 O +ATOM 267 CB ASN A 35 8.746 43.906 18.006 1.00 65.66 C +ANISOU 267 CB ASN A 35 12106 6085 6754 -155 -1790 1501 C +ATOM 268 CG ASN A 35 7.688 44.736 18.712 1.00 66.46 C +ANISOU 268 CG ASN A 35 12095 5993 7161 25 -1965 1467 C +ATOM 269 OD1 ASN A 35 7.887 45.906 19.012 1.00 67.86 O +ANISOU 269 OD1 ASN A 35 12350 6015 7418 14 -2012 1501 O +ATOM 270 ND2 ASN A 35 6.545 44.120 18.972 1.00 65.86 N +ANISOU 270 ND2 ASN A 35 11832 5921 7267 192 -2057 1393 N +ATOM 271 N THR A 36 10.977 46.574 18.565 1.00 67.21 N +ANISOU 271 N THR A 36 12588 6089 6859 -443 -1625 1613 N +ATOM 272 CA THR A 36 11.853 47.204 19.564 1.00 66.52 C +ANISOU 272 CA THR A 36 12430 6010 6832 -488 -1461 1552 C +ATOM 273 C THR A 36 11.323 47.100 21.019 1.00 64.32 C +ANISOU 273 C THR A 36 11885 5740 6811 -293 -1410 1392 C +ATOM 274 O THR A 36 12.100 47.097 21.961 1.00 62.17 O +ANISOU 274 O THR A 36 11501 5561 6559 -324 -1226 1304 O +ATOM 275 CB THR A 36 12.083 48.698 19.211 1.00 69.62 C +ANISOU 275 CB THR A 36 13064 6170 7215 -593 -1597 1676 C +ATOM 276 OG1 THR A 36 12.290 48.846 17.790 1.00 71.92 O +ANISOU 276 OG1 THR A 36 13638 6415 7271 -763 -1694 1838 O +ATOM 277 CG2 THR A 36 13.288 49.253 19.981 1.00 69.34 C +ANISOU 277 CG2 THR A 36 13002 6177 7166 -713 -1402 1634 C +ATOM 278 N THR A 37 10.005 47.017 21.189 1.00 64.54 N +ANISOU 278 N THR A 37 11815 5671 7034 -103 -1572 1352 N +ATOM 279 CA THR A 37 9.365 46.900 22.509 1.00 63.52 C +ANISOU 279 CA THR A 37 11443 5544 7147 75 -1515 1194 C +ATOM 280 C THR A 37 9.676 45.584 23.220 1.00 60.96 C +ANISOU 280 C THR A 37 10909 5468 6783 98 -1295 1070 C +ATOM 281 O THR A 37 9.790 45.550 24.451 1.00 58.96 O +ANISOU 281 O THR A 37 10503 5260 6637 157 -1162 946 O +ATOM 282 CB THR A 37 7.835 46.995 22.360 1.00 65.30 C +ANISOU 282 CB THR A 37 11596 5619 7594 265 -1736 1180 C +ATOM 283 OG1 THR A 37 7.525 48.170 21.607 1.00 69.93 O +ANISOU 283 OG1 THR A 37 12391 5960 8220 248 -1976 1310 O +ATOM 284 CG2 THR A 37 7.123 47.059 23.708 1.00 65.23 C +ANISOU 284 CG2 THR A 37 11351 5582 7849 441 -1667 1010 C +ATOM 285 N GLU A 38 9.783 44.505 22.440 1.00 60.06 N +ANISOU 285 N GLU A 38 10803 5502 6513 50 -1267 1106 N +ATOM 286 CA GLU A 38 10.131 43.192 22.969 1.00 57.83 C +ANISOU 286 CA GLU A 38 10348 5445 6179 63 -1075 1005 C +ATOM 287 C GLU A 38 11.650 42.964 23.086 1.00 54.02 C +ANISOU 287 C GLU A 38 9889 5112 5523 -95 -870 1005 C +ATOM 288 O GLU A 38 12.068 41.898 23.510 1.00 51.23 O +ANISOU 288 O GLU A 38 9401 4936 5128 -91 -718 929 O +ATOM 289 CB GLU A 38 9.461 42.100 22.131 1.00 60.66 C +ANISOU 289 CB GLU A 38 10691 5878 6477 100 -1145 1025 C +ATOM 290 CG GLU A 38 7.980 41.950 22.471 1.00 64.59 C +ANISOU 290 CG GLU A 38 11045 6293 7200 283 -1284 965 C +ATOM 291 CD GLU A 38 7.174 41.090 21.472 1.00 67.70 C +ANISOU 291 CD GLU A 38 11457 6713 7551 311 -1422 1008 C +ATOM 292 OE1 GLU A 38 7.589 39.939 21.163 1.00 68.12 O +ANISOU 292 OE1 GLU A 38 11495 6937 7451 254 -1310 991 O +ATOM 293 OE2 GLU A 38 6.088 41.557 21.023 1.00 70.53 O +ANISOU 293 OE2 GLU A 38 11839 6914 8046 397 -1653 1054 O +ATOM 294 N LYS A 39 12.463 43.971 22.754 1.00 52.83 N +ANISOU 294 N LYS A 39 9899 4882 5291 -233 -870 1088 N +ATOM 295 CA LYS A 39 13.927 43.875 22.802 1.00 51.69 C +ANISOU 295 CA LYS A 39 9768 4866 5004 -398 -683 1091 C +ATOM 296 C LYS A 39 14.613 45.144 23.397 1.00 50.69 C +ANISOU 296 C LYS A 39 9701 4631 4925 -482 -665 1104 C +ATOM 297 O LYS A 39 15.545 45.687 22.813 1.00 52.11 O +ANISOU 297 O LYS A 39 10019 4801 4978 -658 -620 1185 O +ATOM 298 CB LYS A 39 14.372 43.615 21.369 1.00 53.81 C +ANISOU 298 CB LYS A 39 10210 5178 5055 -543 -678 1198 C +ATOM 299 CG LYS A 39 15.845 43.455 21.079 1.00 55.34 C +ANISOU 299 CG LYS A 39 10430 5506 5090 -730 -478 1210 C +ATOM 300 CD LYS A 39 16.112 44.037 19.688 1.00 58.28 C +ANISOU 300 CD LYS A 39 11073 5801 5270 -904 -531 1350 C +ATOM 301 CE LYS A 39 17.583 44.365 19.522 1.00 60.56 C +ANISOU 301 CE LYS A 39 11400 6167 5441 -1114 -340 1369 C +ATOM 302 NZ LYS A 39 17.966 44.437 18.077 1.00 62.98 N +ANISOU 302 NZ LYS A 39 11946 6473 5508 -1304 -311 1477 N +ATOM 303 N PRO A 40 14.163 45.612 24.579 1.00 48.42 N +ANISOU 303 N PRO A 40 9314 4263 4818 -369 -688 1015 N +ATOM 304 CA PRO A 40 14.697 46.850 25.158 1.00 48.26 C +ANISOU 304 CA PRO A 40 9365 4117 4851 -442 -691 1019 C +ATOM 305 C PRO A 40 16.102 46.769 25.782 1.00 46.38 C +ANISOU 305 C PRO A 40 9062 4013 4547 -580 -516 978 C +ATOM 306 O PRO A 40 16.597 47.780 26.237 1.00 47.61 O +ANISOU 306 O PRO A 40 9282 4067 4738 -659 -521 983 O +ATOM 307 CB PRO A 40 13.666 47.193 26.239 1.00 48.28 C +ANISOU 307 CB PRO A 40 9270 4006 5067 -262 -754 910 C +ATOM 308 CG PRO A 40 13.186 45.868 26.701 1.00 47.18 C +ANISOU 308 CG PRO A 40 8939 4031 4956 -145 -674 813 C +ATOM 309 CD PRO A 40 13.205 44.961 25.494 1.00 47.05 C +ANISOU 309 CD PRO A 40 8955 4122 4797 -184 -686 893 C +ATOM 310 N PHE A 41 16.707 45.583 25.837 1.00 44.02 N +ANISOU 310 N PHE A 41 8629 3927 4170 -604 -375 935 N +ATOM 311 CA PHE A 41 18.115 45.390 26.240 1.00 42.63 C +ANISOU 311 CA PHE A 41 8373 3888 3936 -741 -222 908 C +ATOM 312 C PHE A 41 18.743 44.322 25.338 1.00 42.04 C +ANISOU 312 C PHE A 41 8258 3988 3724 -812 -108 934 C +ATOM 313 O PHE A 41 18.034 43.484 24.798 1.00 40.84 O +ANISOU 313 O PHE A 41 8095 3883 3538 -722 -134 935 O +ATOM 314 CB PHE A 41 18.210 44.937 27.701 1.00 40.80 C +ANISOU 314 CB PHE A 41 7963 3732 3805 -657 -163 780 C +ATOM 315 CG PHE A 41 17.411 43.711 27.986 1.00 39.10 C +ANISOU 315 CG PHE A 41 7618 3614 3622 -501 -150 710 C +ATOM 316 CD1 PHE A 41 17.922 42.454 27.737 1.00 37.81 C +ANISOU 316 CD1 PHE A 41 7345 3632 3387 -511 -50 692 C +ATOM 317 CD2 PHE A 41 16.122 43.811 28.471 1.00 38.75 C +ANISOU 317 CD2 PHE A 41 7559 3471 3691 -345 -234 657 C +ATOM 318 CE1 PHE A 41 17.151 41.323 27.967 1.00 36.67 C +ANISOU 318 CE1 PHE A 41 7096 3563 3271 -375 -46 633 C +ATOM 319 CE2 PHE A 41 15.353 42.672 28.711 1.00 37.30 C +ANISOU 319 CE2 PHE A 41 7256 3377 3539 -217 -217 594 C +ATOM 320 CZ PHE A 41 15.868 41.435 28.460 1.00 36.16 C +ANISOU 320 CZ PHE A 41 7021 3406 3310 -235 -128 587 C +ATOM 321 N HIS A 42 20.062 44.348 25.196 1.00 42.75 N +ANISOU 321 N HIS A 42 8320 4174 3747 -974 19 946 N +ATOM 322 CA HIS A 42 20.779 43.316 24.477 1.00 43.41 C +ANISOU 322 CA HIS A 42 8336 4431 3727 -1039 160 942 C +ATOM 323 C HIS A 42 21.029 42.086 25.384 1.00 41.73 C +ANISOU 323 C HIS A 42 7889 4376 3589 -933 239 828 C +ATOM 324 O HIS A 42 21.521 42.222 26.492 1.00 40.45 O +ANISOU 324 O HIS A 42 7614 4236 3520 -931 254 769 O +ATOM 325 CB HIS A 42 22.107 43.848 23.926 1.00 45.52 C +ANISOU 325 CB HIS A 42 8647 4734 3912 -1262 281 991 C +ATOM 326 CG HIS A 42 22.746 42.933 22.927 1.00 47.01 C +ANISOU 326 CG HIS A 42 8807 5073 3980 -1342 437 990 C +ATOM 327 ND1 HIS A 42 22.406 42.937 21.583 1.00 49.39 N +ANISOU 327 ND1 HIS A 42 9303 5343 4120 -1411 435 1071 N +ATOM 328 CD2 HIS A 42 23.690 41.971 23.069 1.00 47.05 C +ANISOU 328 CD2 HIS A 42 8617 5253 4005 -1362 598 910 C +ATOM 329 CE1 HIS A 42 23.119 42.025 20.941 1.00 49.66 C +ANISOU 329 CE1 HIS A 42 9269 5531 4068 -1477 609 1032 C +ATOM 330 NE2 HIS A 42 23.899 41.418 21.821 1.00 49.00 N +ANISOU 330 NE2 HIS A 42 8938 5571 4106 -1439 711 932 N +ATOM 331 N LEU A 43 20.678 40.901 24.883 1.00 41.51 N +ANISOU 331 N LEU A 43 7811 4447 3513 -854 277 802 N +ATOM 332 CA LEU A 43 20.929 39.628 25.573 1.00 40.86 C +ANISOU 332 CA LEU A 43 7529 4507 3488 -760 349 707 C +ATOM 333 C LEU A 43 22.216 38.947 25.141 1.00 41.78 C +ANISOU 333 C LEU A 43 7538 4770 3564 -858 511 680 C +ATOM 334 O LEU A 43 22.420 38.690 23.968 1.00 43.76 O +ANISOU 334 O LEU A 43 7865 5059 3701 -931 590 712 O +ATOM 335 CB LEU A 43 19.770 38.668 25.352 1.00 39.89 C +ANISOU 335 CB LEU A 43 7402 4398 3357 -610 293 683 C +ATOM 336 CG LEU A 43 19.703 37.480 26.302 1.00 38.58 C +ANISOU 336 CG LEU A 43 7057 4331 3269 -490 321 590 C +ATOM 337 CD1 LEU A 43 19.687 37.972 27.723 1.00 37.89 C +ANISOU 337 CD1 LEU A 43 6904 4199 3290 -455 274 546 C +ATOM 338 CD2 LEU A 43 18.480 36.632 26.004 1.00 38.19 C +ANISOU 338 CD2 LEU A 43 7020 4278 3210 -361 260 575 C +ATOM 339 N ASN A 44 23.039 38.621 26.113 1.00 42.31 N +ANISOU 339 N ASN A 44 7429 4914 3730 -855 557 616 N +ATOM 340 CA ASN A 44 24.415 38.221 25.930 1.00 44.15 C +ANISOU 340 CA ASN A 44 7524 5268 3983 -955 699 583 C +ATOM 341 C ASN A 44 24.653 36.955 26.791 1.00 42.56 C +ANISOU 341 C ASN A 44 7119 5169 3882 -832 707 494 C +ATOM 342 O ASN A 44 23.866 36.650 27.670 1.00 39.72 O +ANISOU 342 O ASN A 44 6747 4776 3567 -707 605 469 O +ATOM 343 CB ASN A 44 25.257 39.387 26.435 1.00 47.01 C +ANISOU 343 CB ASN A 44 7877 5585 4399 -1094 693 607 C +ATOM 344 CG ASN A 44 26.717 39.199 26.197 1.00 49.58 C +ANISOU 344 CG ASN A 44 8051 6021 4765 -1224 838 578 C +ATOM 345 OD1 ASN A 44 27.168 39.159 25.064 1.00 53.01 O +ANISOU 345 OD1 ASN A 44 8525 6499 5115 -1330 972 598 O +ATOM 346 ND2 ASN A 44 27.475 39.065 27.276 1.00 51.24 N +ANISOU 346 ND2 ASN A 44 8082 6277 5108 -1220 813 526 N +ATOM 347 N TYR A 45 25.717 36.201 26.538 1.00 43.45 N +ANISOU 347 N TYR A 45 7076 5397 4035 -867 830 445 N +ATOM 348 CA TYR A 45 25.947 34.966 27.274 1.00 43.29 C +ANISOU 348 CA TYR A 45 6876 5455 4115 -746 820 370 C +ATOM 349 C TYR A 45 27.367 34.463 27.200 1.00 45.51 C +ANISOU 349 C TYR A 45 6952 5841 4497 -803 936 314 C +ATOM 350 O TYR A 45 28.079 34.731 26.255 1.00 46.64 O +ANISOU 350 O TYR A 45 7089 6025 4607 -924 1079 316 O +ATOM 351 CB TYR A 45 25.019 33.839 26.790 1.00 42.25 C +ANISOU 351 CB TYR A 45 6786 5342 3923 -615 821 346 C +ATOM 352 CG TYR A 45 25.198 33.472 25.336 1.00 43.39 C +ANISOU 352 CG TYR A 45 6988 5533 3964 -669 961 343 C +ATOM 353 CD1 TYR A 45 26.180 32.575 24.929 1.00 44.20 C +ANISOU 353 CD1 TYR A 45 6940 5736 4114 -678 1105 271 C +ATOM 354 CD2 TYR A 45 24.376 34.034 24.357 1.00 43.85 C +ANISOU 354 CD2 TYR A 45 7259 5524 3874 -714 946 409 C +ATOM 355 CE1 TYR A 45 26.335 32.245 23.588 1.00 45.56 C +ANISOU 355 CE1 TYR A 45 7184 5949 4174 -739 1254 254 C +ATOM 356 CE2 TYR A 45 24.540 33.734 23.015 1.00 45.15 C +ANISOU 356 CE2 TYR A 45 7512 5727 3913 -786 1072 408 C +ATOM 357 CZ TYR A 45 25.517 32.855 22.623 1.00 45.94 C +ANISOU 357 CZ TYR A 45 7475 5934 4045 -804 1238 327 C +ATOM 358 OH TYR A 45 25.629 32.575 21.274 1.00 46.91 O +ANISOU 358 OH TYR A 45 7711 6090 4022 -885 1378 315 O +ATOM 359 N HIS A 46 27.761 33.714 28.224 1.00 46.76 N +ANISOU 359 N HIS A 46 6944 6038 4784 -717 871 263 N +ATOM 360 CA HIS A 46 28.993 32.948 28.204 1.00 49.16 C +ANISOU 360 CA HIS A 46 7019 6435 5221 -722 957 196 C +ATOM 361 C HIS A 46 28.699 31.494 28.597 1.00 47.17 C +ANISOU 361 C HIS A 46 6682 6212 5027 -552 909 141 C +ATOM 362 O HIS A 46 27.976 31.242 29.554 1.00 45.87 O +ANISOU 362 O HIS A 46 6565 6002 4862 -460 765 155 O +ATOM 363 CB HIS A 46 30.047 33.550 29.138 1.00 52.57 C +ANISOU 363 CB HIS A 46 7307 6875 5793 -806 893 194 C +ATOM 364 CG HIS A 46 31.412 32.953 28.946 1.00 57.07 C +ANISOU 364 CG HIS A 46 7620 7537 6526 -834 992 126 C +ATOM 365 ND1 HIS A 46 32.015 32.136 29.882 1.00 58.58 N +ANISOU 365 ND1 HIS A 46 7613 7754 6888 -746 889 80 N +ATOM 366 CD2 HIS A 46 32.266 33.010 27.890 1.00 61.27 C +ANISOU 366 CD2 HIS A 46 8058 8135 7084 -936 1192 90 C +ATOM 367 CE1 HIS A 46 33.188 31.732 29.421 1.00 62.19 C +ANISOU 367 CE1 HIS A 46 7845 8288 7495 -779 1012 15 C +ATOM 368 NE2 HIS A 46 33.365 32.247 28.214 1.00 63.58 N +ANISOU 368 NE2 HIS A 46 8074 8495 7585 -898 1213 13 N +ATOM 369 N VAL A 47 29.280 30.558 27.860 1.00 46.76 N +ANISOU 369 N VAL A 47 6510 6230 5025 -521 1040 76 N +ATOM 370 CA VAL A 47 28.984 29.151 27.963 1.00 46.11 C +ANISOU 370 CA VAL A 47 6370 6162 4985 -367 1018 22 C +ATOM 371 C VAL A 47 30.185 28.408 28.532 1.00 47.94 C +ANISOU 371 C VAL A 47 6344 6439 5430 -321 1005 -43 C +ATOM 372 O VAL A 47 31.320 28.712 28.181 1.00 50.20 O +ANISOU 372 O VAL A 47 6474 6777 5820 -410 1115 -79 O +ATOM 373 CB VAL A 47 28.686 28.581 26.556 1.00 46.41 C +ANISOU 373 CB VAL A 47 6486 6231 4916 -359 1183 -16 C +ATOM 374 CG1 VAL A 47 28.611 27.059 26.572 1.00 46.47 C +ANISOU 374 CG1 VAL A 47 6408 6253 4993 -209 1184 -90 C +ATOM 375 CG2 VAL A 47 27.391 29.151 26.023 1.00 45.28 C +ANISOU 375 CG2 VAL A 47 6598 6031 4576 -381 1151 52 C +ATOM 376 N ASP A 48 29.942 27.445 29.418 1.00 48.15 N +ANISOU 376 N ASP A 48 6324 6440 5531 -189 865 -56 N +ATOM 377 CA ASP A 48 30.948 26.449 29.793 1.00 50.71 C +ANISOU 377 CA ASP A 48 6414 6789 6062 -108 839 -123 C +ATOM 378 C ASP A 48 30.385 25.043 29.542 1.00 50.29 C +ANISOU 378 C ASP A 48 6386 6718 6003 41 842 -168 C +ATOM 379 O ASP A 48 29.195 24.800 29.670 1.00 46.96 O +ANISOU 379 O ASP A 48 6145 6253 5443 92 779 -131 O +ATOM 380 CB ASP A 48 31.385 26.590 31.259 1.00 52.35 C +ANISOU 380 CB ASP A 48 6537 6964 6389 -101 625 -87 C +ATOM 381 CG ASP A 48 32.138 27.905 31.540 1.00 55.06 C +ANISOU 381 CG ASP A 48 6822 7322 6772 -254 614 -56 C +ATOM 382 OD1 ASP A 48 32.992 28.316 30.714 1.00 59.09 O +ANISOU 382 OD1 ASP A 48 7211 7891 7349 -346 776 -94 O +ATOM 383 OD2 ASP A 48 31.887 28.538 32.591 1.00 54.89 O +ANISOU 383 OD2 ASP A 48 6885 7254 6714 -295 451 1 O +ATOM 384 N HIS A 49 31.253 24.126 29.145 1.00 53.47 N +ANISOU 384 N HIS A 49 6600 7149 6566 108 925 -258 N +ATOM 385 CA HIS A 49 30.892 22.726 28.974 1.00 54.52 C +ANISOU 385 CA HIS A 49 6735 7250 6728 254 918 -311 C +ATOM 386 C HIS A 49 31.497 21.929 30.116 1.00 55.43 C +ANISOU 386 C HIS A 49 6689 7322 7050 358 729 -318 C +ATOM 387 O HIS A 49 32.642 22.150 30.496 1.00 57.33 O +ANISOU 387 O HIS A 49 6719 7582 7481 335 696 -339 O +ATOM 388 CB HIS A 49 31.413 22.198 27.640 1.00 57.03 C +ANISOU 388 CB HIS A 49 6970 7615 7081 263 1156 -423 C +ATOM 389 CG HIS A 49 30.807 22.863 26.451 1.00 58.19 C +ANISOU 389 CG HIS A 49 7307 7797 7004 155 1329 -413 C +ATOM 390 ND1 HIS A 49 29.666 22.389 25.839 1.00 58.02 N +ANISOU 390 ND1 HIS A 49 7492 7747 6803 195 1350 -408 N +ATOM 391 CD2 HIS A 49 31.188 23.955 25.745 1.00 60.47 C +ANISOU 391 CD2 HIS A 49 7619 8139 7218 0 1478 -402 C +ATOM 392 CE1 HIS A 49 29.363 23.163 24.810 1.00 59.34 C +ANISOU 392 CE1 HIS A 49 7808 7946 6792 74 1488 -390 C +ATOM 393 NE2 HIS A 49 30.271 24.122 24.731 1.00 61.17 N +ANISOU 393 NE2 HIS A 49 7940 8224 7075 -47 1572 -384 N +ATOM 394 N LEU A 50 30.708 21.026 30.678 1.00 55.10 N +ANISOU 394 N LEU A 50 6753 7213 6969 463 593 -292 N +ATOM 395 CA LEU A 50 31.164 20.125 31.722 1.00 56.16 C +ANISOU 395 CA LEU A 50 6778 7283 7274 567 395 -288 C +ATOM 396 C LEU A 50 31.463 18.766 31.125 1.00 58.29 C +ANISOU 396 C LEU A 50 6947 7523 7676 702 461 -384 C +ATOM 397 O LEU A 50 30.543 18.031 30.740 1.00 58.49 O +ANISOU 397 O LEU A 50 7124 7513 7586 763 491 -395 O +ATOM 398 CB LEU A 50 30.085 19.967 32.783 1.00 54.62 C +ANISOU 398 CB LEU A 50 6788 7022 6943 581 204 -196 C +ATOM 399 CG LEU A 50 29.622 21.286 33.381 1.00 53.38 C +ANISOU 399 CG LEU A 50 6759 6881 6641 455 152 -115 C +ATOM 400 CD1 LEU A 50 28.447 21.075 34.335 1.00 51.84 C +ANISOU 400 CD1 LEU A 50 6772 6623 6299 466 10 -45 C +ATOM 401 CD2 LEU A 50 30.798 21.917 34.092 1.00 54.84 C +ANISOU 401 CD2 LEU A 50 6782 7079 6975 394 49 -100 C +ATOM 402 N ASP A 51 32.752 18.433 31.031 1.00 60.72 N +ANISOU 402 N ASP A 51 6992 7840 8237 750 485 -461 N +ATOM 403 CA ASP A 51 33.173 17.074 30.669 1.00 61.77 C +ANISOU 403 CA ASP A 51 7000 7920 8551 902 512 -561 C +ATOM 404 C ASP A 51 32.567 16.030 31.631 1.00 60.25 C +ANISOU 404 C ASP A 51 6920 7611 8361 1013 270 -501 C +ATOM 405 O ASP A 51 32.167 14.944 31.194 1.00 61.71 O +ANISOU 405 O ASP A 51 7160 7737 8547 1117 307 -555 O +ATOM 406 CB ASP A 51 34.706 16.963 30.656 1.00 64.50 C +ANISOU 406 CB ASP A 51 7010 8280 9215 941 535 -648 C +ATOM 407 N SER A 52 32.493 16.362 32.923 1.00 57.92 N +ANISOU 407 N SER A 52 6675 7278 8053 978 28 -390 N +ATOM 408 CA SER A 52 31.989 15.425 33.925 1.00 56.18 C +ANISOU 408 CA SER A 52 6576 6944 7824 1057 -207 -321 C +ATOM 409 C SER A 52 31.031 16.078 34.924 1.00 52.48 C +ANISOU 409 C SER A 52 6344 6468 7128 953 -345 -196 C +ATOM 410 O SER A 52 30.808 17.276 34.898 1.00 51.40 O +ANISOU 410 O SER A 52 6263 6404 6862 833 -276 -164 O +ATOM 411 CB SER A 52 33.154 14.745 34.652 1.00 58.27 C +ANISOU 411 CB SER A 52 6627 7130 8382 1156 -414 -331 C +ATOM 412 OG SER A 52 33.764 15.637 35.553 1.00 58.92 O +ANISOU 412 OG SER A 52 6639 7236 8513 1066 -569 -262 O +ATOM 413 N SER A 53 30.430 15.245 35.758 1.00 50.72 N +ANISOU 413 N SER A 53 6268 6148 6853 999 -524 -133 N +ATOM 414 CA SER A 53 29.510 15.694 36.790 1.00 48.71 C +ANISOU 414 CA SER A 53 6242 5874 6389 904 -648 -28 C +ATOM 415 C SER A 53 30.137 15.586 38.208 1.00 49.79 C +ANISOU 415 C SER A 53 6371 5937 6607 887 -933 51 C +ATOM 416 O SER A 53 29.454 15.810 39.200 1.00 49.22 O +ANISOU 416 O SER A 53 6502 5833 6364 807 -1052 135 O +ATOM 417 CB SER A 53 28.209 14.889 36.697 1.00 47.04 C +ANISOU 417 CB SER A 53 6243 5612 6017 932 -622 -11 C +ATOM 418 OG SER A 53 27.659 14.892 35.376 1.00 45.77 O +ANISOU 418 OG SER A 53 6093 5507 5788 949 -390 -84 O +ATOM 419 N ASN A 54 31.431 15.247 38.281 1.00 51.06 N +ANISOU 419 N ASN A 54 6299 6069 7031 960 -1040 20 N +ATOM 420 CA ASN A 54 32.245 15.310 39.511 1.00 51.55 C +ANISOU 420 CA ASN A 54 6313 6070 7204 935 -1326 92 C +ATOM 421 C ASN A 54 32.160 16.685 40.205 1.00 49.50 C +ANISOU 421 C ASN A 54 6144 5872 6792 771 -1365 152 C +ATOM 422 O ASN A 54 32.201 17.711 39.556 1.00 48.84 O +ANISOU 422 O ASN A 54 5999 5888 6667 701 -1178 111 O +ATOM 423 CB ASN A 54 33.707 14.945 39.165 1.00 54.29 C +ANISOU 423 CB ASN A 54 6328 6403 7897 1039 -1376 20 C +ATOM 424 CG ASN A 54 34.714 15.547 40.118 1.00 56.55 C +ANISOU 424 CG ASN A 54 6493 6678 8313 975 -1610 74 C +ATOM 425 OD1 ASN A 54 34.936 16.753 40.099 1.00 56.63 O +ANISOU 425 OD1 ASN A 54 6466 6780 8269 853 -1538 74 O +ATOM 426 ND2 ASN A 54 35.370 14.698 40.935 1.00 58.76 N +ANISOU 426 ND2 ASN A 54 6710 6836 8778 1056 -1907 119 N +ATOM 427 N SER A 55 32.092 16.683 41.529 1.00 48.37 N +ANISOU 427 N SER A 55 6152 5657 6566 706 -1616 248 N +ATOM 428 CA SER A 55 31.627 17.848 42.271 1.00 46.46 C +ANISOU 428 CA SER A 55 6089 5453 6108 546 -1636 302 C +ATOM 429 C SER A 55 32.558 19.065 42.158 1.00 45.96 C +ANISOU 429 C SER A 55 5851 5467 6144 462 -1615 277 C +ATOM 430 O SER A 55 32.113 20.201 42.178 1.00 43.89 O +ANISOU 430 O SER A 55 5691 5264 5721 346 -1508 280 O +ATOM 431 CB SER A 55 31.412 17.461 43.736 1.00 47.42 C +ANISOU 431 CB SER A 55 6430 5472 6114 487 -1913 404 C +ATOM 432 OG SER A 55 30.688 18.456 44.447 1.00 47.00 O +ANISOU 432 OG SER A 55 6603 5446 5808 334 -1892 441 O +ATOM 433 N PHE A 56 33.845 18.812 42.027 1.00 47.64 N +ANISOU 433 N PHE A 56 5791 5670 6636 523 -1719 248 N +ATOM 434 CA PHE A 56 34.814 19.879 41.915 1.00 49.05 C +ANISOU 434 CA PHE A 56 5777 5919 6940 438 -1707 222 C +ATOM 435 C PHE A 56 34.770 20.573 40.550 1.00 48.36 C +ANISOU 435 C PHE A 56 5571 5945 6859 420 -1376 135 C +ATOM 436 O PHE A 56 34.743 21.804 40.427 1.00 47.71 O +ANISOU 436 O PHE A 56 5517 5928 6683 293 -1277 135 O +ATOM 437 CB PHE A 56 36.204 19.313 42.109 1.00 51.91 C +ANISOU 437 CB PHE A 56 5848 6236 7636 517 -1906 205 C +ATOM 438 CG PHE A 56 37.269 20.345 42.053 1.00 53.55 C +ANISOU 438 CG PHE A 56 5832 6511 8001 421 -1914 178 C +ATOM 439 CD1 PHE A 56 37.398 21.261 43.071 1.00 53.82 C +ANISOU 439 CD1 PHE A 56 5984 6536 7928 270 -2096 247 C +ATOM 440 CD2 PHE A 56 38.135 20.407 40.979 1.00 55.05 C +ANISOU 440 CD2 PHE A 56 5702 6773 8441 469 -1727 76 C +ATOM 441 CE1 PHE A 56 38.395 22.217 43.038 1.00 55.59 C +ANISOU 441 CE1 PHE A 56 6001 6816 8303 169 -2115 224 C +ATOM 442 CE2 PHE A 56 39.142 21.358 40.934 1.00 56.57 C +ANISOU 442 CE2 PHE A 56 5676 7028 8790 365 -1729 50 C +ATOM 443 CZ PHE A 56 39.274 22.264 41.965 1.00 56.81 C +ANISOU 443 CZ PHE A 56 5819 7044 8722 215 -1932 128 C +ATOM 444 N SER A 57 34.799 19.751 39.521 1.00 48.45 N +ANISOU 444 N SER A 57 5459 5968 6980 546 -1213 61 N +ATOM 445 CA SER A 57 34.660 20.224 38.176 1.00 47.60 C +ANISOU 445 CA SER A 57 5282 5955 6845 531 -899 -18 C +ATOM 446 C SER A 57 33.412 21.089 38.079 1.00 44.69 C +ANISOU 446 C SER A 57 5186 5622 6171 429 -774 22 C +ATOM 447 O SER A 57 33.467 22.205 37.558 1.00 44.63 O +ANISOU 447 O SER A 57 5167 5685 6104 324 -624 7 O +ATOM 448 CB SER A 57 34.631 19.011 37.242 1.00 48.45 C +ANISOU 448 CB SER A 57 5297 6046 7064 685 -769 -99 C +ATOM 449 OG SER A 57 34.356 19.382 35.917 1.00 48.82 O +ANISOU 449 OG SER A 57 5331 6179 7039 662 -465 -173 O +ATOM 450 N VAL A 58 32.301 20.618 38.633 1.00 42.78 N +ANISOU 450 N VAL A 58 5187 5322 5744 451 -847 75 N +ATOM 451 CA VAL A 58 31.023 21.377 38.587 1.00 40.52 C +ANISOU 451 CA VAL A 58 5147 5058 5189 369 -734 104 C +ATOM 452 C VAL A 58 31.025 22.693 39.350 1.00 40.01 C +ANISOU 452 C VAL A 58 5176 5005 5021 225 -800 150 C +ATOM 453 O VAL A 58 30.410 23.660 38.927 1.00 38.67 O +ANISOU 453 O VAL A 58 5104 4872 4713 151 -654 146 O +ATOM 454 CB VAL A 58 29.838 20.522 39.096 1.00 39.35 C +ANISOU 454 CB VAL A 58 5222 4843 4885 418 -795 144 C +ATOM 455 CG1 VAL A 58 28.561 21.347 39.242 1.00 37.83 C +ANISOU 455 CG1 VAL A 58 5258 4666 4450 332 -704 169 C +ATOM 456 CG2 VAL A 58 29.563 19.391 38.125 1.00 39.19 C +ANISOU 456 CG2 VAL A 58 5154 4814 4920 544 -680 90 C +ATOM 457 N THR A 59 31.676 22.707 40.497 1.00 41.42 N +ANISOU 457 N THR A 59 5340 5137 5260 184 -1034 194 N +ATOM 458 CA THR A 59 31.701 23.877 41.348 1.00 41.68 C +ANISOU 458 CA THR A 59 5482 5165 5187 42 -1121 232 C +ATOM 459 C THR A 59 32.555 24.939 40.670 1.00 43.24 C +ANISOU 459 C THR A 59 5501 5432 5496 -34 -1013 196 C +ATOM 460 O THR A 59 32.153 26.104 40.580 1.00 41.96 O +ANISOU 460 O THR A 59 5447 5291 5205 -139 -919 199 O +ATOM 461 CB THR A 59 32.254 23.516 42.740 1.00 42.40 C +ANISOU 461 CB THR A 59 5612 5182 5315 12 -1424 291 C +ATOM 462 OG1 THR A 59 31.460 22.463 43.281 1.00 41.27 O +ANISOU 462 OG1 THR A 59 5645 4971 5063 75 -1507 328 O +ATOM 463 CG2 THR A 59 32.225 24.713 43.680 1.00 42.20 C +ANISOU 463 CG2 THR A 59 5736 5144 5153 -146 -1517 323 C +ATOM 464 N ASN A 60 33.720 24.506 40.182 1.00 46.16 N +ANISOU 464 N ASN A 60 5593 5829 6114 17 -1021 157 N +ATOM 465 CA ASN A 60 34.634 25.360 39.429 1.00 48.35 C +ANISOU 465 CA ASN A 60 5665 6178 6526 -57 -893 113 C +ATOM 466 C ASN A 60 33.916 26.049 38.257 1.00 46.89 C +ANISOU 466 C ASN A 60 5567 6051 6197 -96 -609 84 C +ATOM 467 O ASN A 60 34.044 27.246 38.040 1.00 47.19 O +ANISOU 467 O ASN A 60 5626 6118 6184 -222 -531 89 O +ATOM 468 CB ASN A 60 35.791 24.513 38.903 1.00 51.65 C +ANISOU 468 CB ASN A 60 5766 6618 7239 38 -889 52 C +ATOM 469 CG ASN A 60 37.087 25.283 38.783 1.00 55.47 C +ANISOU 469 CG ASN A 60 5995 7152 7929 -60 -892 22 C +ATOM 470 OD1 ASN A 60 37.318 26.277 39.487 1.00 57.56 O +ANISOU 470 OD1 ASN A 60 6314 7409 8147 -197 -1009 66 O +ATOM 471 ND2 ASN A 60 37.969 24.805 37.897 1.00 58.43 N +ANISOU 471 ND2 ASN A 60 6082 7574 8544 2 -760 -60 N +ATOM 472 N ALA A 61 33.137 25.287 37.515 1.00 45.84 N +ANISOU 472 N ALA A 61 5501 5923 5993 6 -474 59 N +ATOM 473 CA ALA A 61 32.440 25.821 36.378 1.00 44.76 C +ANISOU 473 CA ALA A 61 5456 5830 5719 -22 -235 38 C +ATOM 474 C ALA A 61 31.383 26.832 36.788 1.00 43.74 C +ANISOU 474 C ALA A 61 5579 5671 5368 -107 -242 90 C +ATOM 475 O ALA A 61 31.310 27.927 36.219 1.00 43.38 O +ANISOU 475 O ALA A 61 5575 5650 5257 -205 -121 94 O +ATOM 476 CB ALA A 61 31.815 24.689 35.592 1.00 43.95 C +ANISOU 476 CB ALA A 61 5381 5728 5589 106 -124 0 C +ATOM 477 N PHE A 62 30.553 26.469 37.756 1.00 43.67 N +ANISOU 477 N PHE A 62 5742 5603 5247 -73 -375 127 N +ATOM 478 CA PHE A 62 29.529 27.374 38.266 1.00 43.87 C +ANISOU 478 CA PHE A 62 5996 5590 5080 -144 -380 160 C +ATOM 479 C PHE A 62 30.126 28.680 38.771 1.00 46.58 C +ANISOU 479 C PHE A 62 6341 5926 5430 -283 -437 176 C +ATOM 480 O PHE A 62 29.585 29.747 38.506 1.00 45.48 O +ANISOU 480 O PHE A 62 6320 5776 5185 -354 -348 181 O +ATOM 481 CB PHE A 62 28.761 26.732 39.416 1.00 43.64 C +ANISOU 481 CB PHE A 62 6129 5500 4950 -107 -521 188 C +ATOM 482 CG PHE A 62 27.684 27.609 39.990 1.00 42.62 C +ANISOU 482 CG PHE A 62 6223 5331 4639 -174 -505 201 C +ATOM 483 CD1 PHE A 62 26.380 27.493 39.558 1.00 41.58 C +ANISOU 483 CD1 PHE A 62 6219 5189 4389 -125 -387 191 C +ATOM 484 CD2 PHE A 62 27.983 28.561 40.955 1.00 43.70 C +ANISOU 484 CD2 PHE A 62 6435 5434 4735 -287 -609 214 C +ATOM 485 CE1 PHE A 62 25.399 28.311 40.065 1.00 40.83 C +ANISOU 485 CE1 PHE A 62 6301 5051 4159 -176 -362 188 C +ATOM 486 CE2 PHE A 62 27.006 29.393 41.460 1.00 43.25 C +ANISOU 486 CE2 PHE A 62 6577 5331 4522 -343 -576 208 C +ATOM 487 CZ PHE A 62 25.708 29.264 41.006 1.00 41.74 C +ANISOU 487 CZ PHE A 62 6491 5131 4236 -282 -446 192 C +ATOM 488 N CYS A 63 31.222 28.602 39.523 1.00 50.72 N +ANISOU 488 N CYS A 63 6740 6446 6084 -323 -601 184 N +ATOM 489 CA CYS A 63 31.781 29.799 40.134 1.00 54.62 C +ANISOU 489 CA CYS A 63 7249 6922 6579 -466 -685 200 C +ATOM 490 C CYS A 63 32.430 30.703 39.106 1.00 55.81 C +ANISOU 490 C CYS A 63 7271 7125 6809 -549 -531 180 C +ATOM 491 O CYS A 63 32.369 31.921 39.261 1.00 56.90 O +ANISOU 491 O CYS A 63 7505 7237 6877 -669 -520 192 O +ATOM 492 CB CYS A 63 32.771 29.458 41.248 1.00 58.87 C +ANISOU 492 CB CYS A 63 7695 7435 7235 -495 -933 219 C +ATOM 493 SG CYS A 63 31.998 28.800 42.752 1.00 63.45 S +ANISOU 493 SG CYS A 63 8519 7934 7655 -472 -1143 260 S +ATOM 494 N SER A 64 33.054 30.132 38.073 1.00 56.22 N +ANISOU 494 N SER A 64 7117 7241 7002 -497 -408 145 N +ATOM 495 CA SER A 64 33.654 30.947 37.033 1.00 57.77 C +ANISOU 495 CA SER A 64 7204 7489 7256 -593 -234 125 C +ATOM 496 C SER A 64 32.577 31.822 36.396 1.00 55.89 C +ANISOU 496 C SER A 64 7188 7227 6818 -637 -90 147 C +ATOM 497 O SER A 64 32.816 32.996 36.130 1.00 57.46 O +ANISOU 497 O SER A 64 7420 7418 6992 -768 -34 162 O +ATOM 498 CB SER A 64 34.350 30.097 35.971 1.00 59.80 C +ANISOU 498 CB SER A 64 7230 7818 7671 -524 -87 69 C +ATOM 499 OG SER A 64 33.394 29.504 35.104 1.00 60.57 O +ANISOU 499 OG SER A 64 7439 7924 7648 -426 61 54 O +ATOM 500 N GLN A 65 31.389 31.267 36.205 1.00 53.37 N +ANISOU 500 N GLN A 65 7022 6886 6367 -530 -49 151 N +ATOM 501 CA GLN A 65 30.278 32.034 35.657 1.00 51.60 C +ANISOU 501 CA GLN A 65 7003 6626 5973 -553 53 173 C +ATOM 502 C GLN A 65 29.652 32.994 36.624 1.00 49.41 C +ANISOU 502 C GLN A 65 6912 6270 5591 -613 -48 199 C +ATOM 503 O GLN A 65 29.222 34.099 36.243 1.00 48.80 O +ANISOU 503 O GLN A 65 6958 6150 5433 -686 15 217 O +ATOM 504 CB GLN A 65 29.194 31.108 35.125 1.00 51.31 C +ANISOU 504 CB GLN A 65 7052 6592 5849 -421 121 164 C +ATOM 505 CG GLN A 65 29.649 30.454 33.856 1.00 52.73 C +ANISOU 505 CG GLN A 65 7102 6840 6090 -386 275 130 C +ATOM 506 CD GLN A 65 28.537 29.871 33.061 1.00 51.88 C +ANISOU 506 CD GLN A 65 7113 6729 5869 -295 364 125 C +ATOM 507 OE1 GLN A 65 27.382 29.897 33.464 1.00 51.49 O +ANISOU 507 OE1 GLN A 65 7223 6627 5712 -250 308 147 O +ATOM 508 NE2 GLN A 65 28.900 29.263 31.946 1.00 52.61 N +ANISOU 508 NE2 GLN A 65 7118 6876 5995 -268 504 87 N +ATOM 509 N PHE A 66 29.574 32.576 37.873 1.00 48.19 N +ANISOU 509 N PHE A 66 6794 6085 5432 -586 -207 198 N +ATOM 510 CA PHE A 66 29.070 33.463 38.897 1.00 47.52 C +ANISOU 510 CA PHE A 66 6887 5922 5244 -654 -298 206 C +ATOM 511 C PHE A 66 29.948 34.712 38.986 1.00 49.28 C +ANISOU 511 C PHE A 66 7079 6127 5516 -806 -324 214 C +ATOM 512 O PHE A 66 29.441 35.826 39.119 1.00 47.79 O +ANISOU 512 O PHE A 66 7046 5870 5241 -875 -305 217 O +ATOM 513 CB PHE A 66 29.007 32.758 40.248 1.00 46.48 C +ANISOU 513 CB PHE A 66 6807 5765 5089 -625 -468 204 C +ATOM 514 CG PHE A 66 28.479 33.625 41.327 1.00 45.62 C +ANISOU 514 CG PHE A 66 6897 5577 4858 -703 -542 196 C +ATOM 515 CD1 PHE A 66 27.125 33.839 41.449 1.00 44.21 C +ANISOU 515 CD1 PHE A 66 6903 5348 4546 -660 -466 176 C +ATOM 516 CD2 PHE A 66 29.342 34.264 42.195 1.00 47.04 C +ANISOU 516 CD2 PHE A 66 7077 5729 5065 -825 -683 199 C +ATOM 517 CE1 PHE A 66 26.630 34.660 42.443 1.00 44.87 C +ANISOU 517 CE1 PHE A 66 7170 5353 4524 -731 -510 149 C +ATOM 518 CE2 PHE A 66 28.864 35.096 43.182 1.00 47.64 C +ANISOU 518 CE2 PHE A 66 7356 5725 5017 -905 -740 179 C +ATOM 519 CZ PHE A 66 27.504 35.301 43.304 1.00 46.72 C +ANISOU 519 CZ PHE A 66 7425 5558 4767 -856 -643 149 C +ATOM 520 N SER A 67 31.260 34.513 38.882 1.00 52.41 N +ANISOU 520 N SER A 67 7265 6579 6067 -857 -364 213 N +ATOM 521 CA SER A 67 32.214 35.614 39.010 1.00 55.70 C +ANISOU 521 CA SER A 67 7623 6985 6554 -1017 -401 220 C +ATOM 522 C SER A 67 32.144 36.623 37.857 1.00 56.67 C +ANISOU 522 C SER A 67 7781 7103 6647 -1100 -226 233 C +ATOM 523 O SER A 67 32.387 37.796 38.074 1.00 58.31 O +ANISOU 523 O SER A 67 8059 7256 6838 -1233 -252 245 O +ATOM 524 CB SER A 67 33.645 35.079 39.162 1.00 57.80 C +ANISOU 524 CB SER A 67 7621 7316 7025 -1047 -489 210 C +ATOM 525 OG SER A 67 34.057 34.315 38.041 1.00 58.24 O +ANISOU 525 OG SER A 67 7482 7453 7191 -977 -341 189 O +ATOM 526 N ARG A 68 31.806 36.172 36.651 1.00 56.75 N +ANISOU 526 N ARG A 68 7760 7160 6641 -1031 -60 233 N +ATOM 527 CA ARG A 68 31.615 37.064 35.499 1.00 56.91 C +ANISOU 527 CA ARG A 68 7856 7166 6600 -1111 98 258 C +ATOM 528 C ARG A 68 30.482 38.068 35.654 1.00 54.65 C +ANISOU 528 C ARG A 68 7827 6768 6168 -1125 83 283 C +ATOM 529 O ARG A 68 30.446 39.075 34.956 1.00 55.36 O +ANISOU 529 O ARG A 68 8003 6813 6216 -1223 159 315 O +ATOM 530 CB ARG A 68 31.357 36.248 34.240 1.00 58.35 C +ANISOU 530 CB ARG A 68 7989 7414 6764 -1026 261 250 C +ATOM 531 CG ARG A 68 32.612 35.622 33.655 1.00 61.55 C +ANISOU 531 CG ARG A 68 8137 7922 7325 -1054 352 214 C +ATOM 532 CD ARG A 68 32.255 34.602 32.599 1.00 62.77 C +ANISOU 532 CD ARG A 68 8263 8134 7450 -945 498 188 C +ATOM 533 NE ARG A 68 33.204 34.650 31.490 1.00 66.93 N +ANISOU 533 NE ARG A 68 8643 8737 8049 -1038 685 160 N +ATOM 534 CZ ARG A 68 34.424 34.121 31.505 1.00 69.95 C +ANISOU 534 CZ ARG A 68 8758 9194 8626 -1052 719 105 C +ATOM 535 NH1 ARG A 68 34.881 33.468 32.567 1.00 71.38 N +ANISOU 535 NH1 ARG A 68 8789 9378 8954 -974 550 81 N +ATOM 536 NH2 ARG A 68 35.197 34.246 30.439 1.00 72.52 N +ANISOU 536 NH2 ARG A 68 8964 9586 9001 -1151 924 71 N +ATOM 537 N GLY A 69 29.552 37.780 36.548 1.00 52.80 N +ANISOU 537 N GLY A 69 7713 6483 5862 -1029 -9 267 N +ATOM 538 CA GLY A 69 28.480 38.711 36.873 1.00 51.79 C +ANISOU 538 CA GLY A 69 7808 6242 5627 -1030 -29 270 C +ATOM 539 C GLY A 69 27.181 38.467 36.134 1.00 49.85 C +ANISOU 539 C GLY A 69 7673 5970 5296 -913 54 278 C +ATOM 540 O GLY A 69 26.393 39.395 35.933 1.00 53.52 O +ANISOU 540 O GLY A 69 8293 6336 5702 -922 68 291 O +ATOM 541 N VAL A 70 26.933 37.227 35.743 1.00 45.91 N +ANISOU 541 N VAL A 70 7094 5548 4801 -799 95 270 N +ATOM 542 CA VAL A 70 25.683 36.876 35.085 1.00 43.45 C +ANISOU 542 CA VAL A 70 6875 5216 4416 -688 155 275 C +ATOM 543 C VAL A 70 24.480 37.112 35.995 1.00 41.08 C +ANISOU 543 C VAL A 70 6717 4829 4060 -622 95 246 C +ATOM 544 O VAL A 70 24.605 37.059 37.192 1.00 41.51 O +ANISOU 544 O VAL A 70 6786 4869 4115 -635 16 214 O +ATOM 545 CB VAL A 70 25.687 35.403 34.639 1.00 43.60 C +ANISOU 545 CB VAL A 70 6781 5329 4454 -583 198 261 C +ATOM 546 CG1 VAL A 70 26.849 35.138 33.678 1.00 44.66 C +ANISOU 546 CG1 VAL A 70 6766 5549 4652 -642 289 269 C +ATOM 547 CG2 VAL A 70 25.731 34.452 35.846 1.00 43.32 C +ANISOU 547 CG2 VAL A 70 6695 5317 4447 -518 100 228 C +ATOM 548 N TYR A 71 23.320 37.356 35.409 1.00 39.32 N +ANISOU 548 N TYR A 71 6598 4549 3792 -555 134 254 N +ATOM 549 CA TYR A 71 22.082 37.639 36.141 1.00 37.83 C +ANISOU 549 CA TYR A 71 6526 4273 3574 -486 105 213 C +ATOM 550 C TYR A 71 21.158 36.434 36.257 1.00 35.47 C +ANISOU 550 C TYR A 71 6204 4016 3256 -362 121 186 C +ATOM 551 O TYR A 71 20.126 36.507 36.917 1.00 35.22 O +ANISOU 551 O TYR A 71 6245 3928 3209 -307 115 141 O +ATOM 552 CB TYR A 71 21.294 38.737 35.425 1.00 38.96 C +ANISOU 552 CB TYR A 71 6785 4305 3710 -483 121 236 C +ATOM 553 CG TYR A 71 21.977 40.074 35.411 1.00 41.33 C +ANISOU 553 CG TYR A 71 7150 4528 4024 -608 98 261 C +ATOM 554 CD1 TYR A 71 21.702 41.017 36.395 1.00 42.59 C +ANISOU 554 CD1 TYR A 71 7410 4579 4193 -637 52 214 C +ATOM 555 CD2 TYR A 71 22.870 40.425 34.393 1.00 42.20 C +ANISOU 555 CD2 TYR A 71 7232 4666 4134 -707 133 326 C +ATOM 556 CE1 TYR A 71 22.290 42.281 36.352 1.00 44.40 C +ANISOU 556 CE1 TYR A 71 7713 4720 4436 -757 25 237 C +ATOM 557 CE2 TYR A 71 23.479 41.671 34.364 1.00 43.62 C +ANISOU 557 CE2 TYR A 71 7480 4768 4326 -838 113 353 C +ATOM 558 CZ TYR A 71 23.179 42.594 35.339 1.00 44.61 C +ANISOU 558 CZ TYR A 71 7706 4776 4465 -859 51 312 C +ATOM 559 OH TYR A 71 23.776 43.838 35.359 1.00 47.32 O +ANISOU 559 OH TYR A 71 8128 5027 4823 -994 23 335 O +ATOM 560 N ALA A 72 21.484 35.361 35.550 1.00 33.89 N +ANISOU 560 N ALA A 72 5905 3908 3061 -322 153 207 N +ATOM 561 CA ALA A 72 20.791 34.098 35.666 1.00 32.40 C +ANISOU 561 CA ALA A 72 5686 3763 2859 -219 161 185 C +ATOM 562 C ALA A 72 21.643 33.093 34.945 1.00 32.47 C +ANISOU 562 C ALA A 72 5575 3869 2893 -208 191 204 C +ATOM 563 O ALA A 72 22.542 33.465 34.193 1.00 34.26 O +ANISOU 563 O ALA A 72 5750 4124 3141 -273 230 230 O +ATOM 564 CB ALA A 72 19.398 34.147 35.061 1.00 31.59 C +ANISOU 564 CB ALA A 72 5651 3611 2738 -138 190 182 C +ATOM 565 N ILE A 73 21.385 31.822 35.187 1.00 31.56 N +ANISOU 565 N ILE A 73 5415 3797 2779 -130 182 184 N +ATOM 566 CA ILE A 73 22.165 30.762 34.588 1.00 31.50 C +ANISOU 566 CA ILE A 73 5290 3867 2811 -102 209 186 C +ATOM 567 C ILE A 73 21.227 29.745 33.983 1.00 30.34 C +ANISOU 567 C ILE A 73 5161 3733 2633 -6 244 175 C +ATOM 568 O ILE A 73 20.355 29.234 34.674 1.00 29.73 O +ANISOU 568 O ILE A 73 5130 3631 2533 44 208 158 O +ATOM 569 CB ILE A 73 23.057 30.058 35.617 1.00 31.69 C +ANISOU 569 CB ILE A 73 5226 3921 2892 -105 129 173 C +ATOM 570 CG1 ILE A 73 24.118 31.032 36.110 1.00 33.05 C +ANISOU 570 CG1 ILE A 73 5361 4086 3107 -212 84 183 C +ATOM 571 CG2 ILE A 73 23.743 28.866 34.979 1.00 31.70 C +ANISOU 571 CG2 ILE A 73 5097 3987 2959 -49 159 162 C +ATOM 572 CD1 ILE A 73 25.085 30.444 37.126 1.00 33.78 C +ANISOU 572 CD1 ILE A 73 5365 4200 3269 -226 -28 178 C +ATOM 573 N PHE A 74 21.412 29.463 32.702 1.00 30.01 N +ANISOU 573 N PHE A 74 5090 3729 2583 3 318 182 N +ATOM 574 CA PHE A 74 20.692 28.388 32.045 1.00 29.54 C +ANISOU 574 CA PHE A 74 5041 3685 2495 85 345 167 C +ATOM 575 C PHE A 74 21.588 27.149 32.092 1.00 29.96 C +ANISOU 575 C PHE A 74 4977 3794 2610 126 355 137 C +ATOM 576 O PHE A 74 22.790 27.240 31.867 1.00 31.11 O +ANISOU 576 O PHE A 74 5022 3980 2816 86 391 129 O +ATOM 577 CB PHE A 74 20.391 28.757 30.593 1.00 29.65 C +ANISOU 577 CB PHE A 74 5117 3700 2449 65 413 187 C +ATOM 578 CG PHE A 74 19.782 27.642 29.816 1.00 29.22 C +ANISOU 578 CG PHE A 74 5078 3664 2359 134 438 167 C +ATOM 579 CD1 PHE A 74 18.434 27.381 29.915 1.00 28.43 C +ANISOU 579 CD1 PHE A 74 5046 3522 2233 191 387 168 C +ATOM 580 CD2 PHE A 74 20.551 26.833 29.023 1.00 29.86 C +ANISOU 580 CD2 PHE A 74 5099 3801 2444 140 516 137 C +ATOM 581 CE1 PHE A 74 17.857 26.343 29.227 1.00 28.00 C +ANISOU 581 CE1 PHE A 74 5009 3479 2148 245 397 149 C +ATOM 582 CE2 PHE A 74 19.978 25.785 28.331 1.00 29.69 C +ANISOU 582 CE2 PHE A 74 5106 3787 2384 200 535 111 C +ATOM 583 CZ PHE A 74 18.625 25.548 28.433 1.00 28.54 C +ANISOU 583 CZ PHE A 74 5040 3599 2205 248 467 121 C +ATOM 584 N GLY A 75 21.029 25.991 32.378 1.00 29.47 N +ANISOU 584 N GLY A 75 4919 3727 2550 204 323 118 N +ATOM 585 CA GLY A 75 21.853 24.792 32.366 1.00 30.11 C +ANISOU 585 CA GLY A 75 4894 3840 2705 255 322 88 C +ATOM 586 C GLY A 75 21.193 23.469 32.634 1.00 29.33 C +ANISOU 586 C GLY A 75 4819 3720 2604 336 281 71 C +ATOM 587 O GLY A 75 19.982 23.378 32.812 1.00 28.41 O +ANISOU 587 O GLY A 75 4797 3571 2423 352 262 80 O +ATOM 588 N PHE A 76 22.035 22.448 32.686 1.00 30.07 N +ANISOU 588 N PHE A 76 4815 3824 2784 387 265 44 N +ATOM 589 CA PHE A 76 21.600 21.067 32.826 1.00 30.23 C +ANISOU 589 CA PHE A 76 4854 3814 2818 466 226 26 C +ATOM 590 C PHE A 76 22.229 20.441 34.010 1.00 30.97 C +ANISOU 590 C PHE A 76 4899 3876 2991 489 104 40 C +ATOM 591 O PHE A 76 23.349 20.757 34.340 1.00 32.35 O +ANISOU 591 O PHE A 76 4971 4066 3254 470 67 41 O +ATOM 592 CB PHE A 76 22.021 20.271 31.592 1.00 30.68 C +ANISOU 592 CB PHE A 76 4850 3893 2911 519 320 -29 C +ATOM 593 CG PHE A 76 21.332 20.705 30.359 1.00 30.35 C +ANISOU 593 CG PHE A 76 4889 3873 2767 491 422 -38 C +ATOM 594 CD1 PHE A 76 21.768 21.837 29.674 1.00 30.83 C +ANISOU 594 CD1 PHE A 76 4943 3974 2796 418 504 -30 C +ATOM 595 CD2 PHE A 76 20.213 20.029 29.912 1.00 29.96 C +ANISOU 595 CD2 PHE A 76 4936 3797 2648 525 420 -48 C +ATOM 596 CE1 PHE A 76 21.124 22.258 28.534 1.00 30.92 C +ANISOU 596 CE1 PHE A 76 5054 3993 2698 382 575 -26 C +ATOM 597 CE2 PHE A 76 19.550 20.440 28.757 1.00 30.17 C +ANISOU 597 CE2 PHE A 76 5049 3837 2576 494 484 -49 C +ATOM 598 CZ PHE A 76 20.007 21.559 28.069 1.00 30.56 C +ANISOU 598 CZ PHE A 76 5105 3920 2584 423 556 -35 C +ATOM 599 N TYR A 77 21.510 19.534 34.648 1.00 31.53 N +ANISOU 599 N TYR A 77 5049 3896 3032 521 32 53 N +ATOM 600 CA TYR A 77 22.102 18.692 35.686 1.00 32.89 C +ANISOU 600 CA TYR A 77 5199 4020 3275 549 -103 74 C +ATOM 601 C TYR A 77 21.687 17.260 35.486 1.00 33.27 C +ANISOU 601 C TYR A 77 5281 4018 3341 624 -125 58 C +ATOM 602 O TYR A 77 20.767 16.963 34.730 1.00 32.27 O +ANISOU 602 O TYR A 77 5214 3894 3151 639 -43 35 O +ATOM 603 CB TYR A 77 21.762 19.205 37.084 1.00 32.72 C +ANISOU 603 CB TYR A 77 5282 3970 3179 473 -203 125 C +ATOM 604 CG TYR A 77 20.306 19.411 37.370 1.00 32.15 C +ANISOU 604 CG TYR A 77 5353 3884 2976 431 -159 134 C +ATOM 605 CD1 TYR A 77 19.416 18.364 37.329 1.00 32.08 C +ANISOU 605 CD1 TYR A 77 5415 3839 2932 461 -156 131 C +ATOM 606 CD2 TYR A 77 19.822 20.653 37.747 1.00 32.61 C +ANISOU 606 CD2 TYR A 77 5471 3957 2960 357 -122 139 C +ATOM 607 CE1 TYR A 77 18.078 18.529 37.638 1.00 31.85 C +ANISOU 607 CE1 TYR A 77 5495 3800 2807 417 -109 131 C +ATOM 608 CE2 TYR A 77 18.468 20.839 38.052 1.00 32.25 C +ANISOU 608 CE2 TYR A 77 5534 3894 2823 325 -72 133 C +ATOM 609 CZ TYR A 77 17.601 19.761 37.993 1.00 31.85 C +ANISOU 609 CZ TYR A 77 5533 3818 2748 353 -63 128 C +ATOM 610 OH TYR A 77 16.269 19.901 38.280 1.00 31.74 O +ANISOU 610 OH TYR A 77 5601 3791 2668 318 -5 114 O +ATOM 611 N ASP A 78 22.411 16.370 36.135 1.00 35.49 N +ANISOU 611 N ASP A 78 5524 4244 3717 670 -249 71 N +ATOM 612 CA ASP A 78 22.052 14.966 36.183 1.00 37.43 C +ANISOU 612 CA ASP A 78 5822 4414 3983 734 -303 68 C +ATOM 613 C ASP A 78 22.011 14.549 37.661 1.00 38.54 C +ANISOU 613 C ASP A 78 6065 4480 4097 696 -478 140 C +ATOM 614 O ASP A 78 22.246 15.370 38.528 1.00 38.22 O +ANISOU 614 O ASP A 78 6049 4454 4015 622 -541 180 O +ATOM 615 CB ASP A 78 23.034 14.136 35.350 1.00 39.16 C +ANISOU 615 CB ASP A 78 5899 4615 4363 843 -282 4 C +ATOM 616 CG ASP A 78 24.448 14.082 35.953 1.00 41.59 C +ANISOU 616 CG ASP A 78 6064 4899 4840 879 -407 13 C +ATOM 617 OD1 ASP A 78 24.769 14.805 36.932 1.00 41.62 O +ANISOU 617 OD1 ASP A 78 6077 4910 4825 810 -511 71 O +ATOM 618 OD2 ASP A 78 25.263 13.305 35.416 1.00 44.67 O +ANISOU 618 OD2 ASP A 78 6323 5256 5391 979 -402 -45 O +ATOM 619 N GLN A 79 21.722 13.281 37.935 1.00 40.20 N +ANISOU 619 N GLN A 79 6349 4604 4320 737 -559 156 N +ATOM 620 CA AGLN A 79 21.589 12.769 39.299 0.50 41.19 C +ANISOU 620 CA AGLN A 79 6610 4645 4393 685 -727 234 C +ATOM 621 CA BGLN A 79 21.569 12.830 39.317 0.50 40.95 C +ANISOU 621 CA BGLN A 79 6583 4619 4357 680 -724 234 C +ATOM 622 C GLN A 79 22.820 13.121 40.136 1.00 42.54 C +ANISOU 622 C GLN A 79 6716 4798 4649 677 -889 274 C +ATOM 623 O GLN A 79 22.712 13.443 41.304 1.00 41.95 O +ANISOU 623 O GLN A 79 6765 4698 4475 583 -996 338 O +ATOM 624 CB AGLN A 79 21.370 11.247 39.250 0.50 42.06 C +ANISOU 624 CB AGLN A 79 6783 4648 4547 749 -800 241 C +ATOM 625 CB BGLN A 79 21.182 11.353 39.387 0.50 41.45 C +ANISOU 625 CB BGLN A 79 6735 4576 4437 726 -795 249 C +ATOM 626 CG AGLN A 79 20.893 10.587 40.537 0.50 43.11 C +ANISOU 626 CG AGLN A 79 7112 4685 4581 671 -946 327 C +ATOM 627 CG BGLN A 79 19.676 11.112 39.340 0.50 40.60 C +ANISOU 627 CG BGLN A 79 6775 4469 4181 656 -697 252 C +ATOM 628 CD AGLN A 79 20.588 9.112 40.339 0.50 43.91 C +ANISOU 628 CD AGLN A 79 7283 4674 4725 728 -1001 332 C +ATOM 629 CD BGLN A 79 18.961 11.415 40.653 0.50 40.52 C +ANISOU 629 CD BGLN A 79 6940 4442 4012 521 -743 319 C +ATOM 630 OE1AGLN A 79 20.985 8.515 39.334 0.50 44.50 O +ANISOU 630 OE1AGLN A 79 7243 4730 4934 846 -962 267 O +ATOM 631 OE1BGLN A 79 18.737 12.571 40.999 0.50 40.22 O +ANISOU 631 OE1BGLN A 79 6912 4474 3893 446 -681 318 O +ATOM 632 NE2AGLN A 79 19.854 8.527 41.276 0.50 44.23 N +ANISOU 632 NE2AGLN A 79 7523 4638 4644 635 -1079 403 N +ATOM 633 NE2BGLN A 79 18.609 10.372 41.395 0.50 41.36 N +ANISOU 633 NE2BGLN A 79 7195 4448 4070 481 -846 374 N +ATOM 634 N MET A 80 23.996 13.056 39.511 1.00 44.90 N +ANISOU 634 N MET A 80 6817 5107 5133 771 -902 230 N +ATOM 635 CA MET A 80 25.268 13.354 40.205 1.00 47.84 C +ANISOU 635 CA MET A 80 7085 5462 5631 773 -1070 262 C +ATOM 636 C MET A 80 25.521 14.832 40.524 1.00 45.34 C +ANISOU 636 C MET A 80 6742 5232 5253 671 -1039 271 C +ATOM 637 O MET A 80 26.137 15.124 41.530 1.00 45.57 O +ANISOU 637 O MET A 80 6787 5231 5294 618 -1212 325 O +ATOM 638 CB MET A 80 26.460 12.830 39.408 1.00 52.14 C +ANISOU 638 CB MET A 80 7392 5992 6424 906 -1075 195 C +ATOM 639 CG MET A 80 26.698 11.341 39.572 1.00 57.08 C +ANISOU 639 CG MET A 80 8026 6486 7174 1015 -1219 204 C +ATOM 640 SD MET A 80 28.134 10.719 38.644 1.00 65.73 S +ANISOU 640 SD MET A 80 8818 7556 8601 1187 -1207 101 S +ATOM 641 CE MET A 80 29.485 11.819 39.129 1.00 66.01 C +ANISOU 641 CE MET A 80 8644 7652 8783 1147 -1306 113 C +ATOM 642 N SER A 81 25.069 15.746 39.662 1.00 42.53 N +ANISOU 642 N SER A 81 6353 4971 4832 642 -835 221 N +ATOM 643 CA SER A 81 25.398 17.170 39.781 1.00 41.58 C +ANISOU 643 CA SER A 81 6192 4925 4680 555 -793 221 C +ATOM 644 C SER A 81 24.261 18.028 40.335 1.00 40.17 C +ANISOU 644 C SER A 81 6201 4766 4294 444 -735 246 C +ATOM 645 O SER A 81 24.467 19.191 40.652 1.00 38.36 O +ANISOU 645 O SER A 81 5974 4573 4024 363 -727 251 O +ATOM 646 CB SER A 81 25.860 17.731 38.415 1.00 40.73 C +ANISOU 646 CB SER A 81 5911 4901 4661 590 -612 149 C +ATOM 647 OG SER A 81 24.805 17.791 37.460 1.00 38.22 O +ANISOU 647 OG SER A 81 5664 4619 4237 598 -434 115 O +ATOM 648 N MET A 82 23.074 17.447 40.460 1.00 41.23 N +ANISOU 648 N MET A 82 6484 4869 4312 439 -694 255 N +ATOM 649 CA MET A 82 21.870 18.191 40.804 1.00 42.55 C +ANISOU 649 CA MET A 82 6798 5057 4311 351 -600 256 C +ATOM 650 C MET A 82 22.005 18.936 42.123 1.00 42.37 C +ANISOU 650 C MET A 82 6888 5015 4193 239 -696 293 C +ATOM 651 O MET A 82 21.796 20.136 42.184 1.00 41.23 O +ANISOU 651 O MET A 82 6763 4909 3992 176 -622 273 O +ATOM 652 CB MET A 82 20.684 17.248 40.842 1.00 45.68 C +ANISOU 652 CB MET A 82 7316 5414 4626 360 -561 260 C +ATOM 653 CG MET A 82 19.342 17.927 41.049 1.00 48.72 C +ANISOU 653 CG MET A 82 7816 5821 4873 284 -438 242 C +ATOM 654 SD MET A 82 18.819 17.844 42.771 1.00 58.49 S +ANISOU 654 SD MET A 82 9268 7001 5954 156 -517 285 S +ATOM 655 CE MET A 82 18.366 16.091 42.886 1.00 57.81 C +ANISOU 655 CE MET A 82 9264 6839 5861 185 -579 321 C +ATOM 656 N ASN A 83 22.374 18.203 43.166 1.00 42.74 N +ANISOU 656 N ASN A 83 7023 4992 4222 212 -872 347 N +ATOM 657 CA ASN A 83 22.530 18.741 44.498 1.00 43.75 C +ANISOU 657 CA ASN A 83 7294 5089 4238 93 -988 387 C +ATOM 658 C ASN A 83 23.571 19.870 44.580 1.00 42.22 C +ANISOU 658 C ASN A 83 6998 4933 4111 57 -1042 379 C +ATOM 659 O ASN A 83 23.315 20.859 45.237 1.00 41.57 O +ANISOU 659 O ASN A 83 7023 4858 3912 -47 -1023 371 O +ATOM 660 CB ASN A 83 22.866 17.595 45.481 1.00 47.17 C +ANISOU 660 CB ASN A 83 7843 5427 4651 76 -1201 460 C +ATOM 661 CG ASN A 83 22.795 18.005 46.944 1.00 50.11 C +ANISOU 661 CG ASN A 83 8432 5758 4850 -73 -1317 505 C +ATOM 662 OD1 ASN A 83 22.328 19.079 47.298 1.00 51.80 O +ANISOU 662 OD1 ASN A 83 8728 6009 4944 -166 -1216 470 O +ATOM 663 ND2 ASN A 83 23.261 17.112 47.820 1.00 56.13 N +ANISOU 663 ND2 ASN A 83 9305 6429 5593 -100 -1540 583 N +ATOM 664 N THR A 84 24.732 19.725 43.943 1.00 40.96 N +ANISOU 664 N THR A 84 6631 4791 4141 135 -1103 374 N +ATOM 665 CA THR A 84 25.713 20.821 43.886 1.00 40.53 C +ANISOU 665 CA THR A 84 6453 4779 4167 93 -1132 361 C +ATOM 666 C THR A 84 25.122 22.108 43.236 1.00 38.72 C +ANISOU 666 C THR A 84 6223 4615 3870 50 -926 311 C +ATOM 667 O THR A 84 25.188 23.196 43.816 1.00 37.98 O +ANISOU 667 O THR A 84 6200 4524 3705 -49 -942 309 O +ATOM 668 CB THR A 84 27.006 20.406 43.140 1.00 41.20 C +ANISOU 668 CB THR A 84 6279 4880 4493 189 -1186 347 C +ATOM 669 OG1 THR A 84 27.621 19.291 43.795 1.00 42.38 O +ANISOU 669 OG1 THR A 84 6418 4950 4732 237 -1407 395 O +ATOM 670 CG2 THR A 84 28.016 21.563 43.095 1.00 41.93 C +ANISOU 670 CG2 THR A 84 6236 5020 4675 125 -1208 333 C +ATOM 671 N LEU A 85 24.530 21.981 42.049 1.00 37.23 N +ANISOU 671 N LEU A 85 5973 4467 3703 124 -749 271 N +ATOM 672 CA LEU A 85 24.043 23.165 41.332 1.00 36.61 C +ANISOU 672 CA LEU A 85 5890 4437 3582 93 -582 234 C +ATOM 673 C LEU A 85 22.886 23.865 42.073 1.00 35.87 C +ANISOU 673 C LEU A 85 5990 4318 3321 14 -532 226 C +ATOM 674 O LEU A 85 22.880 25.099 42.213 1.00 35.49 O +ANISOU 674 O LEU A 85 5973 4275 3236 -55 -493 210 O +ATOM 675 CB LEU A 85 23.654 22.835 39.889 1.00 36.03 C +ANISOU 675 CB LEU A 85 5729 4404 3555 180 -426 200 C +ATOM 676 CG LEU A 85 24.839 22.523 38.973 1.00 37.30 C +ANISOU 676 CG LEU A 85 5687 4604 3881 239 -411 181 C +ATOM 677 CD1 LEU A 85 24.408 21.816 37.695 1.00 36.73 C +ANISOU 677 CD1 LEU A 85 5570 4555 3830 328 -278 144 C +ATOM 678 CD2 LEU A 85 25.607 23.794 38.652 1.00 38.00 C +ANISOU 678 CD2 LEU A 85 5687 4734 4014 167 -368 172 C +ATOM 679 N THR A 86 21.927 23.079 42.565 1.00 35.32 N +ANISOU 679 N THR A 86 6047 4214 3158 20 -527 232 N +ATOM 680 CA THR A 86 20.755 23.661 43.227 1.00 34.58 C +ANISOU 680 CA THR A 86 6118 4098 2922 -49 -447 207 C +ATOM 681 C THR A 86 21.131 24.288 44.574 1.00 34.64 C +ANISOU 681 C THR A 86 6255 4069 2836 -167 -550 216 C +ATOM 682 O THR A 86 20.566 25.279 44.985 1.00 34.36 O +ANISOU 682 O THR A 86 6315 4021 2717 -234 -473 176 O +ATOM 683 CB THR A 86 19.598 22.652 43.386 1.00 34.26 C +ANISOU 683 CB THR A 86 6170 4035 2810 -28 -394 204 C +ATOM 684 OG1 THR A 86 19.965 21.563 44.251 1.00 35.87 O +ANISOU 684 OG1 THR A 86 6453 4194 2981 -51 -538 254 O +ATOM 685 CG2 THR A 86 19.186 22.111 42.036 1.00 33.27 C +ANISOU 685 CG2 THR A 86 5932 3942 2768 76 -300 188 C +ATOM 686 N SER A 87 22.134 23.726 45.212 1.00 35.52 N +ANISOU 686 N SER A 87 6364 4156 2973 -189 -732 267 N +ATOM 687 CA SER A 87 22.628 24.218 46.492 1.00 36.89 C +ANISOU 687 CA SER A 87 6670 4290 3054 -309 -870 285 C +ATOM 688 C SER A 87 23.408 25.529 46.403 1.00 37.41 C +ANISOU 688 C SER A 87 6667 4375 3171 -362 -887 265 C +ATOM 689 O SER A 87 23.208 26.421 47.209 1.00 38.09 O +ANISOU 689 O SER A 87 6895 4433 3142 -467 -886 239 O +ATOM 690 CB SER A 87 23.524 23.171 47.108 1.00 38.29 C +ANISOU 690 CB SER A 87 6851 4426 3269 -308 -1095 356 C +ATOM 691 OG SER A 87 24.198 23.716 48.204 1.00 40.57 O +ANISOU 691 OG SER A 87 7245 4679 3490 -425 -1259 380 O +ATOM 692 N PHE A 88 24.308 25.635 45.431 1.00 37.78 N +ANISOU 692 N PHE A 88 6501 4465 3388 -296 -895 272 N +ATOM 693 CA PHE A 88 24.990 26.888 45.135 1.00 38.37 C +ANISOU 693 CA PHE A 88 6492 4561 3524 -349 -880 252 C +ATOM 694 C PHE A 88 24.060 27.983 44.641 1.00 38.10 C +ANISOU 694 C PHE A 88 6515 4532 3427 -364 -692 200 C +ATOM 695 O PHE A 88 24.242 29.148 44.983 1.00 38.59 O +ANISOU 695 O PHE A 88 6633 4573 3456 -451 -694 179 O +ATOM 696 CB PHE A 88 26.112 26.680 44.114 1.00 38.29 C +ANISOU 696 CB PHE A 88 6232 4601 3713 -283 -897 264 C +ATOM 697 CG PHE A 88 27.414 26.303 44.740 1.00 39.45 C +ANISOU 697 CG PHE A 88 6287 4733 3967 -310 -1116 303 C +ATOM 698 CD1 PHE A 88 27.596 25.039 45.268 1.00 40.01 C +ANISOU 698 CD1 PHE A 88 6373 4766 4060 -259 -1266 344 C +ATOM 699 CD2 PHE A 88 28.432 27.222 44.832 1.00 40.41 C +ANISOU 699 CD2 PHE A 88 6312 4867 4172 -390 -1187 302 C +ATOM 700 CE1 PHE A 88 28.791 24.683 45.846 1.00 41.87 C +ANISOU 700 CE1 PHE A 88 6517 4975 4415 -275 -1497 384 C +ATOM 701 CE2 PHE A 88 29.633 26.891 45.418 1.00 42.27 C +ANISOU 701 CE2 PHE A 88 6445 5087 4529 -416 -1409 337 C +ATOM 702 CZ PHE A 88 29.813 25.613 45.925 1.00 43.09 C +ANISOU 702 CZ PHE A 88 6555 5150 4667 -352 -1572 379 C +ATOM 703 N CYS A 89 23.077 27.626 43.833 1.00 37.98 N +ANISOU 703 N CYS A 89 6488 4535 3407 -279 -545 181 N +ATOM 704 CA CYS A 89 22.103 28.618 43.389 1.00 38.48 C +ANISOU 704 CA CYS A 89 6607 4587 3426 -281 -390 135 C +ATOM 705 C CYS A 89 21.287 29.208 44.514 1.00 37.99 C +ANISOU 705 C CYS A 89 6737 4469 3229 -359 -366 91 C +ATOM 706 O CYS A 89 21.052 30.408 44.528 1.00 38.24 O +ANISOU 706 O CYS A 89 6816 4468 3244 -402 -305 52 O +ATOM 707 CB CYS A 89 21.182 28.026 42.347 1.00 38.74 C +ANISOU 707 CB CYS A 89 6589 4644 3484 -177 -266 126 C +ATOM 708 SG CYS A 89 22.115 27.982 40.802 1.00 43.93 S +ANISOU 708 SG CYS A 89 7046 5362 4283 -115 -234 149 S +ATOM 709 N GLY A 90 20.845 28.361 45.438 1.00 37.54 N +ANISOU 709 N GLY A 90 6797 4391 3072 -382 -404 94 N +ATOM 710 CA GLY A 90 20.055 28.787 46.572 1.00 37.30 C +ANISOU 710 CA GLY A 90 6963 4311 2896 -470 -358 42 C +ATOM 711 C GLY A 90 20.857 29.612 47.550 1.00 38.79 C +ANISOU 711 C GLY A 90 7255 4462 3018 -593 -471 36 C +ATOM 712 O GLY A 90 20.321 30.527 48.183 1.00 40.36 O +ANISOU 712 O GLY A 90 7592 4614 3126 -665 -397 -31 O +ATOM 713 N ALA A 91 22.140 29.300 47.714 1.00 39.10 N +ANISOU 713 N ALA A 91 7229 4515 3110 -620 -654 99 N +ATOM 714 CA ALA A 91 22.936 30.014 48.701 1.00 40.20 C +ANISOU 714 CA ALA A 91 7472 4615 3184 -749 -793 99 C +ATOM 715 C ALA A 91 23.359 31.384 48.161 1.00 40.13 C +ANISOU 715 C ALA A 91 7388 4602 3257 -773 -750 67 C +ATOM 716 O ALA A 91 23.381 32.360 48.903 1.00 42.24 O +ANISOU 716 O ALA A 91 7794 4817 3438 -879 -764 22 O +ATOM 717 CB ALA A 91 24.136 29.190 49.127 1.00 41.04 C +ANISOU 717 CB ALA A 91 7528 4727 3336 -771 -1029 179 C +ATOM 718 N LEU A 92 23.673 31.473 46.883 1.00 39.04 N +ANISOU 718 N LEU A 92 7050 4510 3272 -686 -693 88 N +ATOM 719 CA LEU A 92 24.086 32.740 46.266 1.00 39.20 C +ANISOU 719 CA LEU A 92 7003 4522 3368 -719 -649 70 C +ATOM 720 C LEU A 92 22.950 33.520 45.535 1.00 38.36 C +ANISOU 720 C LEU A 92 6929 4388 3259 -664 -457 19 C +ATOM 721 O LEU A 92 23.201 34.511 44.848 1.00 38.79 O +ANISOU 721 O LEU A 92 6931 4425 3379 -680 -414 16 O +ATOM 722 CB LEU A 92 25.224 32.455 45.299 1.00 39.47 C +ANISOU 722 CB LEU A 92 6807 4619 3568 -681 -701 125 C +ATOM 723 CG LEU A 92 26.431 31.790 45.946 1.00 40.81 C +ANISOU 723 CG LEU A 92 6907 4806 3793 -724 -908 172 C +ATOM 724 CD1 LEU A 92 27.323 31.155 44.890 1.00 40.90 C +ANISOU 724 CD1 LEU A 92 6664 4886 3989 -645 -914 207 C +ATOM 725 CD2 LEU A 92 27.207 32.805 46.754 1.00 42.37 C +ANISOU 725 CD2 LEU A 92 7168 4961 3968 -868 -1035 164 C +ATOM 726 N HIS A 93 21.710 33.060 45.671 1.00 37.99 N +ANISOU 726 N HIS A 93 6961 4329 3143 -605 -351 -17 N +ATOM 727 CA HIS A 93 20.541 33.785 45.178 1.00 37.63 C +ANISOU 727 CA HIS A 93 6951 4240 3104 -552 -194 -74 C +ATOM 728 C HIS A 93 20.597 34.001 43.657 1.00 36.22 C +ANISOU 728 C HIS A 93 6622 4091 3047 -470 -137 -36 C +ATOM 729 O HIS A 93 20.128 34.989 43.127 1.00 36.82 O +ANISOU 729 O HIS A 93 6716 4115 3158 -456 -65 -61 O +ATOM 730 CB HIS A 93 20.371 35.105 45.938 1.00 38.98 C +ANISOU 730 CB HIS A 93 7269 4324 3218 -642 -174 -145 C +ATOM 731 CG HIS A 93 19.937 34.931 47.358 1.00 40.79 C +ANISOU 731 CG HIS A 93 7682 4516 3300 -719 -174 -206 C +ATOM 732 ND1 HIS A 93 19.223 35.892 48.045 1.00 42.12 N +ANISOU 732 ND1 HIS A 93 8002 4599 3401 -767 -81 -307 N +ATOM 733 CD2 HIS A 93 20.088 33.897 48.215 1.00 41.35 C +ANISOU 733 CD2 HIS A 93 7825 4617 3269 -763 -249 -183 C +ATOM 734 CE1 HIS A 93 18.968 35.459 49.264 1.00 42.79 C +ANISOU 734 CE1 HIS A 93 8249 4673 3336 -848 -84 -349 C +ATOM 735 NE2 HIS A 93 19.467 34.245 49.386 1.00 42.24 N +ANISOU 735 NE2 HIS A 93 8141 4670 3236 -850 -192 -267 N +ATOM 736 N THR A 94 21.162 33.040 42.961 1.00 35.14 N +ANISOU 736 N THR A 94 6351 4028 2971 -419 -172 21 N +ATOM 737 CA THR A 94 21.315 33.098 41.521 1.00 33.97 C +ANISOU 737 CA THR A 94 6077 3917 2913 -358 -115 56 C +ATOM 738 C THR A 94 20.349 32.130 40.878 1.00 32.20 C +ANISOU 738 C THR A 94 5820 3721 2690 -249 -42 57 C +ATOM 739 O THR A 94 20.403 30.952 41.133 1.00 32.23 O +ANISOU 739 O THR A 94 5797 3764 2683 -215 -76 70 O +ATOM 740 CB THR A 94 22.738 32.724 41.180 1.00 34.81 C +ANISOU 740 CB THR A 94 6044 4084 3095 -387 -193 105 C +ATOM 741 OG1 THR A 94 23.589 33.714 41.750 1.00 36.40 O +ANISOU 741 OG1 THR A 94 6271 4255 3304 -500 -266 104 O +ATOM 742 CG2 THR A 94 22.935 32.712 39.687 1.00 35.21 C +ANISOU 742 CG2 THR A 94 5980 4179 3219 -340 -111 133 C +ATOM 743 N SER A 95 19.426 32.621 40.086 1.00 31.28 N +ANISOU 743 N SER A 95 5717 3574 2592 -197 43 43 N +ATOM 744 CA SER A 95 18.403 31.759 39.542 1.00 30.96 C +ANISOU 744 CA SER A 95 5654 3553 2554 -104 101 37 C +ATOM 745 C SER A 95 18.983 30.854 38.442 1.00 30.40 C +ANISOU 745 C SER A 95 5469 3555 2526 -56 98 85 C +ATOM 746 O SER A 95 19.674 31.314 37.538 1.00 30.34 O +ANISOU 746 O SER A 95 5406 3566 2555 -74 109 115 O +ATOM 747 CB SER A 95 17.247 32.588 39.013 1.00 31.11 C +ANISOU 747 CB SER A 95 5713 3508 2598 -61 168 9 C +ATOM 748 OG SER A 95 16.539 33.169 40.091 1.00 32.10 O +ANISOU 748 OG SER A 95 5933 3567 2695 -86 196 -57 O +ATOM 749 N PHE A 96 18.711 29.573 38.574 1.00 29.78 N +ANISOU 749 N PHE A 96 5367 3511 2435 -5 90 84 N +ATOM 750 CA PHE A 96 19.130 28.533 37.642 1.00 29.88 C +ANISOU 750 CA PHE A 96 5284 3581 2486 51 95 110 C +ATOM 751 C PHE A 96 17.914 28.121 36.805 1.00 28.67 C +ANISOU 751 C PHE A 96 5143 3423 2324 123 156 100 C +ATOM 752 O PHE A 96 16.942 27.631 37.343 1.00 27.99 O +ANISOU 752 O PHE A 96 5103 3316 2213 146 166 76 O +ATOM 753 CB PHE A 96 19.671 27.328 38.436 1.00 30.65 C +ANISOU 753 CB PHE A 96 5359 3701 2586 59 19 118 C +ATOM 754 CG PHE A 96 20.324 26.263 37.589 1.00 31.74 C +ANISOU 754 CG PHE A 96 5386 3885 2786 120 17 132 C +ATOM 755 CD1 PHE A 96 21.562 26.498 36.978 1.00 32.77 C +ANISOU 755 CD1 PHE A 96 5404 4055 2991 104 19 142 C +ATOM 756 CD2 PHE A 96 19.743 25.009 37.427 1.00 31.38 C +ANISOU 756 CD2 PHE A 96 5346 3842 2734 187 22 126 C +ATOM 757 CE1 PHE A 96 22.183 25.517 36.211 1.00 32.79 C +ANISOU 757 CE1 PHE A 96 5298 4096 3063 164 38 135 C +ATOM 758 CE2 PHE A 96 20.368 24.027 36.658 1.00 31.44 C +ANISOU 758 CE2 PHE A 96 5259 3881 2806 248 25 126 C +ATOM 759 CZ PHE A 96 21.577 24.287 36.037 1.00 32.14 C +ANISOU 759 CZ PHE A 96 5232 4008 2971 241 40 124 C +ATOM 760 N VAL A 97 17.927 28.373 35.498 1.00 28.38 N +ANISOU 760 N VAL A 97 5076 3401 2305 144 197 118 N +ATOM 761 CA VAL A 97 16.815 27.933 34.641 1.00 27.66 C +ANISOU 761 CA VAL A 97 5000 3303 2206 206 229 113 C +ATOM 762 C VAL A 97 17.229 26.657 33.914 1.00 27.51 C +ANISOU 762 C VAL A 97 4924 3337 2191 249 239 117 C +ATOM 763 O VAL A 97 18.271 26.642 33.298 1.00 27.44 O +ANISOU 763 O VAL A 97 4862 3365 2197 232 260 129 O +ATOM 764 CB VAL A 97 16.457 29.030 33.646 1.00 27.69 C +ANISOU 764 CB VAL A 97 5040 3270 2208 197 247 134 C +ATOM 765 CG1 VAL A 97 15.126 28.716 32.977 1.00 27.41 C +ANISOU 765 CG1 VAL A 97 5029 3210 2176 257 245 128 C +ATOM 766 CG2 VAL A 97 16.410 30.366 34.367 1.00 27.92 C +ANISOU 766 CG2 VAL A 97 5120 3238 2251 149 233 127 C +ATOM 767 N THR A 98 16.421 25.599 33.981 1.00 27.66 N +ANISOU 767 N THR A 98 4952 3354 2203 299 234 100 N +ATOM 768 CA THR A 98 16.844 24.260 33.509 1.00 28.24 C +ANISOU 768 CA THR A 98 4981 3462 2287 342 235 94 C +ATOM 769 C THR A 98 15.760 23.450 32.792 1.00 28.48 C +ANISOU 769 C THR A 98 5037 3483 2298 389 247 80 C +ATOM 770 O THR A 98 14.612 23.468 33.186 1.00 28.83 O +ANISOU 770 O THR A 98 5117 3497 2338 394 237 71 O +ATOM 771 CB THR A 98 17.356 23.414 34.703 1.00 27.96 C +ANISOU 771 CB THR A 98 4929 3424 2271 344 180 91 C +ATOM 772 OG1 THR A 98 18.010 22.236 34.229 1.00 28.48 O +ANISOU 772 OG1 THR A 98 4937 3509 2373 393 173 82 O +ATOM 773 CG2 THR A 98 16.246 22.996 35.595 1.00 27.62 C +ANISOU 773 CG2 THR A 98 4953 3346 2195 340 163 82 C +ATOM 774 N PRO A 99 16.119 22.731 31.734 1.00 29.58 N +ANISOU 774 N PRO A 99 5157 3648 2432 419 272 71 N +ATOM 775 CA PRO A 99 15.162 21.777 31.173 1.00 29.76 C +ANISOU 775 CA PRO A 99 5212 3658 2437 457 266 53 C +ATOM 776 C PRO A 99 15.416 20.350 31.619 1.00 29.78 C +ANISOU 776 C PRO A 99 5195 3655 2465 494 246 33 C +ATOM 777 O PRO A 99 14.763 19.448 31.132 1.00 30.15 O +ANISOU 777 O PRO A 99 5268 3686 2500 520 240 15 O +ATOM 778 CB PRO A 99 15.386 21.900 29.677 1.00 30.15 C +ANISOU 778 CB PRO A 99 5282 3728 2445 455 308 50 C +ATOM 779 CG PRO A 99 16.825 22.270 29.545 1.00 30.95 C +ANISOU 779 CG PRO A 99 5329 3867 2563 431 358 49 C +ATOM 780 CD PRO A 99 17.240 22.988 30.813 1.00 30.88 C +ANISOU 780 CD PRO A 99 5285 3852 2597 403 324 70 C +ATOM 781 N SER A 100 16.338 20.148 32.546 1.00 30.13 N +ANISOU 781 N SER A 100 5199 3699 2547 492 218 40 N +ATOM 782 CA SER A 100 16.535 18.844 33.173 1.00 30.66 C +ANISOU 782 CA SER A 100 5265 3739 2645 525 168 33 C +ATOM 783 C SER A 100 15.361 18.411 34.032 1.00 31.52 C +ANISOU 783 C SER A 100 5445 3809 2721 501 136 43 C +ATOM 784 O SER A 100 14.424 19.166 34.274 1.00 32.90 O +ANISOU 784 O SER A 100 5651 3982 2866 465 158 45 O +ATOM 785 CB SER A 100 17.764 18.864 34.052 1.00 30.94 C +ANISOU 785 CB SER A 100 5247 3773 2733 520 114 49 C +ATOM 786 OG SER A 100 18.905 19.197 33.318 1.00 31.46 O +ANISOU 786 OG SER A 100 5223 3878 2852 535 155 32 O +ATOM 787 N PHE A 101 15.451 17.196 34.533 1.00 32.44 N +ANISOU 787 N PHE A 101 5584 3887 2852 520 85 47 N +ATOM 788 CA PHE A 101 14.359 16.590 35.261 1.00 33.01 C +ANISOU 788 CA PHE A 101 5732 3920 2889 483 68 55 C +ATOM 789 C PHE A 101 14.029 17.403 36.513 1.00 34.60 C +ANISOU 789 C PHE A 101 5979 4119 3045 410 69 73 C +ATOM 790 O PHE A 101 14.931 17.878 37.202 1.00 34.25 O +ANISOU 790 O PHE A 101 5933 4079 3000 391 28 93 O +ATOM 791 CB PHE A 101 14.697 15.128 35.617 1.00 33.06 C +ANISOU 791 CB PHE A 101 5772 3869 2917 508 0 65 C +ATOM 792 CG PHE A 101 15.815 14.972 36.619 1.00 33.20 C +ANISOU 792 CG PHE A 101 5793 3861 2959 506 -90 101 C +ATOM 793 CD1 PHE A 101 15.554 15.025 37.978 1.00 33.80 C +ANISOU 793 CD1 PHE A 101 5962 3907 2974 429 -139 140 C +ATOM 794 CD2 PHE A 101 17.101 14.707 36.207 1.00 33.80 C +ANISOU 794 CD2 PHE A 101 5784 3936 3122 575 -129 92 C +ATOM 795 CE1 PHE A 101 16.576 14.871 38.908 1.00 34.59 C +ANISOU 795 CE1 PHE A 101 6081 3972 3087 418 -253 182 C +ATOM 796 CE2 PHE A 101 18.125 14.547 37.123 1.00 34.67 C +ANISOU 796 CE2 PHE A 101 5881 4014 3278 577 -240 128 C +ATOM 797 CZ PHE A 101 17.865 14.617 38.475 1.00 35.17 C +ANISOU 797 CZ PHE A 101 6052 4042 3269 498 -317 179 C +ATOM 798 N PRO A 102 12.731 17.593 36.794 1.00 36.53 N +ANISOU 798 N PRO A 102 6261 4357 3260 366 120 56 N +ATOM 799 CA PRO A 102 12.361 18.352 37.983 1.00 38.71 C +ANISOU 799 CA PRO A 102 6589 4627 3491 292 148 54 C +ATOM 800 C PRO A 102 12.693 17.591 39.272 1.00 42.89 C +ANISOU 800 C PRO A 102 7217 5118 3961 232 92 85 C +ATOM 801 O PRO A 102 12.572 16.357 39.345 1.00 43.18 O +ANISOU 801 O PRO A 102 7295 5118 3992 232 51 105 O +ATOM 802 CB PRO A 102 10.860 18.529 37.845 1.00 37.59 C +ANISOU 802 CB PRO A 102 6438 4483 3360 270 227 15 C +ATOM 803 CG PRO A 102 10.434 17.397 36.999 1.00 37.30 C +ANISOU 803 CG PRO A 102 6383 4435 3351 305 208 14 C +ATOM 804 CD PRO A 102 11.547 17.175 36.030 1.00 36.59 C +ANISOU 804 CD PRO A 102 6257 4360 3284 377 157 30 C +ATOM 805 N THR A 103 13.109 18.366 40.262 1.00 46.20 N +ANISOU 805 N THR A 103 7687 5535 4329 173 80 93 N +ATOM 806 CA THR A 103 13.596 17.850 41.514 1.00 51.04 C +ANISOU 806 CA THR A 103 8415 6109 4868 104 1 133 C +ATOM 807 C THR A 103 12.471 17.333 42.405 1.00 52.58 C +ANISOU 807 C THR A 103 8729 6273 4976 6 62 123 C +ATOM 808 O THR A 103 11.282 17.682 42.263 1.00 50.07 O +ANISOU 808 O THR A 103 8389 5972 4663 -16 187 70 O +ATOM 809 CB THR A 103 14.376 18.937 42.317 1.00 54.23 C +ANISOU 809 CB THR A 103 8855 6520 5230 53 -35 139 C +ATOM 810 OG1 THR A 103 13.462 19.791 43.015 1.00 55.14 O +ANISOU 810 OG1 THR A 103 9039 6636 5273 -26 72 90 O +ATOM 811 CG2 THR A 103 15.282 19.801 41.384 1.00 54.40 C +ANISOU 811 CG2 THR A 103 8746 6582 5341 126 -50 133 C +ATOM 812 N ASP A 104 12.889 16.495 43.346 1.00 56.74 N +ANISOU 812 N ASP A 104 9382 6749 5428 -54 -31 177 N +ATOM 813 CA ASP A 104 12.002 15.907 44.350 1.00 59.09 C +ANISOU 813 CA ASP A 104 9829 7007 5612 -177 17 181 C +ATOM 814 C ASP A 104 11.739 16.963 45.417 1.00 60.40 C +ANISOU 814 C ASP A 104 10090 7186 5672 -285 97 144 C +ATOM 815 O ASP A 104 10.589 17.362 45.671 1.00 62.65 O +ANISOU 815 O ASP A 104 10386 7487 5928 -347 258 78 O +ATOM 816 CB ASP A 104 12.657 14.669 44.953 1.00 59.96 C +ANISOU 816 CB ASP A 104 10064 7042 5673 -208 -137 265 C +ATOM 817 N ALA A 105 12.833 17.446 45.999 1.00 60.41 N +ANISOU 817 N ALA A 105 10147 7176 5629 -303 -14 179 N +ATOM 818 CA ALA A 105 12.804 18.459 47.037 1.00 60.22 C +ANISOU 818 CA ALA A 105 10235 7154 5492 -408 34 144 C +ATOM 819 C ALA A 105 12.266 19.788 46.513 1.00 58.10 C +ANISOU 819 C ALA A 105 9850 6933 5293 -365 179 55 C +ATOM 820 O ALA A 105 12.405 20.103 45.347 1.00 55.32 O +ANISOU 820 O ALA A 105 9333 6612 5072 -248 180 45 O +ATOM 821 CB ALA A 105 14.204 18.651 47.615 1.00 60.93 C +ANISOU 821 CB ALA A 105 10388 7217 5542 -426 -154 206 C +ATOM 822 N ASP A 106 11.659 20.549 47.420 1.00 58.83 N +ANISOU 822 N ASP A 106 10045 7019 5289 -468 299 -11 N +ATOM 823 CA ASP A 106 11.211 21.908 47.165 1.00 56.54 C +ANISOU 823 CA ASP A 106 9675 6748 5059 -437 423 -100 C +ATOM 824 C ASP A 106 12.374 22.853 47.427 1.00 53.96 C +ANISOU 824 C ASP A 106 9376 6414 4710 -442 318 -84 C +ATOM 825 O ASP A 106 12.717 23.113 48.559 1.00 55.51 O +ANISOU 825 O ASP A 106 9737 6583 4769 -556 289 -88 O +ATOM 826 CB ASP A 106 10.035 22.273 48.087 1.00 59.08 C +ANISOU 826 CB ASP A 106 10094 7055 5296 -547 616 -198 C +ATOM 827 CG ASP A 106 8.826 21.352 47.906 1.00 61.20 C +ANISOU 827 CG ASP A 106 10325 7333 5595 -565 733 -221 C +ATOM 828 OD1 ASP A 106 8.610 20.849 46.778 1.00 62.46 O +ANISOU 828 OD1 ASP A 106 10333 7512 5886 -458 700 -194 O +ATOM 829 OD2 ASP A 106 8.083 21.133 48.892 1.00 62.82 O +ANISOU 829 OD2 ASP A 106 10658 7523 5688 -697 865 -271 O +ATOM 830 N VAL A 107 12.977 23.361 46.367 1.00 50.34 N +ANISOU 830 N VAL A 107 8765 5980 4379 -332 261 -66 N +ATOM 831 CA VAL A 107 14.112 24.268 46.483 1.00 49.51 C +ANISOU 831 CA VAL A 107 8661 5872 4278 -338 162 -49 C +ATOM 832 C VAL A 107 13.757 25.660 45.966 1.00 46.39 C +ANISOU 832 C VAL A 107 8190 5475 3960 -297 261 -118 C +ATOM 833 O VAL A 107 12.768 25.842 45.257 1.00 45.52 O +ANISOU 833 O VAL A 107 7990 5371 3934 -231 373 -164 O +ATOM 834 CB VAL A 107 15.365 23.740 45.741 1.00 49.88 C +ANISOU 834 CB VAL A 107 8599 5941 4411 -262 1 35 C +ATOM 835 CG1 VAL A 107 15.849 22.450 46.378 1.00 51.45 C +ANISOU 835 CG1 VAL A 107 8885 6116 4546 -300 -130 105 C +ATOM 836 CG2 VAL A 107 15.090 23.500 44.263 1.00 49.76 C +ANISOU 836 CG2 VAL A 107 8413 5961 4530 -138 48 37 C +ATOM 837 N GLN A 108 14.564 26.630 46.369 1.00 44.30 N +ANISOU 837 N GLN A 108 7970 5192 3668 -342 203 -124 N +ATOM 838 CA GLN A 108 14.474 27.976 45.871 1.00 43.76 C +ANISOU 838 CA GLN A 108 7842 5106 3676 -308 261 -173 C +ATOM 839 C GLN A 108 15.510 28.194 44.758 1.00 40.62 C +ANISOU 839 C GLN A 108 7308 4738 3385 -237 162 -107 C +ATOM 840 O GLN A 108 16.535 27.520 44.708 1.00 40.00 O +ANISOU 840 O GLN A 108 7198 4688 3311 -239 39 -38 O +ATOM 841 CB GLN A 108 14.727 28.975 46.995 1.00 47.02 C +ANISOU 841 CB GLN A 108 8402 5471 3991 -416 267 -228 C +ATOM 842 CG GLN A 108 13.769 28.888 48.181 1.00 50.26 C +ANISOU 842 CG GLN A 108 8971 5849 4273 -509 391 -311 C +ATOM 843 CD GLN A 108 12.307 28.854 47.771 1.00 51.53 C +ANISOU 843 CD GLN A 108 9057 6008 4514 -446 571 -388 C +ATOM 844 OE1 GLN A 108 11.890 29.513 46.811 1.00 51.24 O +ANISOU 844 OE1 GLN A 108 8886 5960 4620 -345 617 -413 O +ATOM 845 NE2 GLN A 108 11.518 28.077 48.506 1.00 53.55 N +ANISOU 845 NE2 GLN A 108 9400 6268 4679 -514 667 -422 N +ATOM 846 N PHE A 109 15.216 29.161 43.893 1.00 37.64 N +ANISOU 846 N PHE A 109 6853 4347 3099 -181 221 -133 N +ATOM 847 CA PHE A 109 16.124 29.663 42.830 1.00 35.34 C +ANISOU 847 CA PHE A 109 6456 4075 2894 -140 160 -82 C +ATOM 848 C PHE A 109 16.356 28.683 41.694 1.00 33.64 C +ANISOU 848 C PHE A 109 6121 3916 2742 -59 135 -26 C +ATOM 849 O PHE A 109 17.416 28.642 41.112 1.00 32.47 O +ANISOU 849 O PHE A 109 5897 3801 2639 -51 72 20 O +ATOM 850 CB PHE A 109 17.443 30.184 43.406 1.00 35.31 C +ANISOU 850 CB PHE A 109 6485 4067 2861 -223 54 -56 C +ATOM 851 CG PHE A 109 17.278 31.379 44.305 1.00 35.54 C +ANISOU 851 CG PHE A 109 6636 4030 2834 -304 81 -119 C +ATOM 852 CD1 PHE A 109 17.152 32.654 43.769 1.00 35.22 C +ANISOU 852 CD1 PHE A 109 6581 3943 2856 -292 125 -146 C +ATOM 853 CD2 PHE A 109 17.231 31.229 45.675 1.00 35.79 C +ANISOU 853 CD2 PHE A 109 6816 4037 2743 -397 62 -153 C +ATOM 854 CE1 PHE A 109 16.972 33.744 44.577 1.00 35.64 C +ANISOU 854 CE1 PHE A 109 6751 3922 2866 -360 154 -215 C +ATOM 855 CE2 PHE A 109 17.053 32.312 46.487 1.00 36.47 C +ANISOU 855 CE2 PHE A 109 7028 4059 2769 -475 100 -226 C +ATOM 856 CZ PHE A 109 16.926 33.572 45.933 1.00 36.95 C +ANISOU 856 CZ PHE A 109 7060 4070 2910 -450 148 -261 C +ATOM 857 N VAL A 110 15.345 27.890 41.374 1.00 32.83 N +ANISOU 857 N VAL A 110 6001 3824 2650 -5 193 -39 N +ATOM 858 CA VAL A 110 15.497 26.895 40.334 1.00 32.07 C +ANISOU 858 CA VAL A 110 5811 3770 2600 66 172 3 C +ATOM 859 C VAL A 110 14.219 26.892 39.532 1.00 31.71 C +ANISOU 859 C VAL A 110 5732 3716 2600 128 249 -24 C +ATOM 860 O VAL A 110 13.178 26.550 40.054 1.00 33.43 O +ANISOU 860 O VAL A 110 5984 3915 2800 122 305 -64 O +ATOM 861 CB VAL A 110 15.755 25.482 40.896 1.00 32.04 C +ANISOU 861 CB VAL A 110 5831 3784 2557 58 114 30 C +ATOM 862 CG1 VAL A 110 15.999 24.525 39.741 1.00 31.84 C +ANISOU 862 CG1 VAL A 110 5710 3794 2593 138 98 61 C +ATOM 863 CG2 VAL A 110 16.948 25.461 41.846 1.00 32.28 C +ANISOU 863 CG2 VAL A 110 5905 3810 2549 -6 6 60 C +ATOM 864 N ILE A 111 14.293 27.288 38.272 1.00 30.64 N +ANISOU 864 N ILE A 111 5532 3588 2519 178 251 -2 N +ATOM 865 CA ILE A 111 13.130 27.288 37.414 1.00 30.18 C +ANISOU 865 CA ILE A 111 5442 3515 2509 237 289 -18 C +ATOM 866 C ILE A 111 13.180 26.037 36.535 1.00 29.87 C +ANISOU 866 C ILE A 111 5356 3519 2472 282 268 10 C +ATOM 867 O ILE A 111 14.066 25.888 35.696 1.00 29.42 O +ANISOU 867 O ILE A 111 5267 3494 2416 295 243 46 O +ATOM 868 CB ILE A 111 13.069 28.544 36.548 1.00 29.96 C +ANISOU 868 CB ILE A 111 5405 3450 2526 254 285 -7 C +ATOM 869 CG1 ILE A 111 12.667 29.739 37.408 1.00 30.80 C +ANISOU 869 CG1 ILE A 111 5561 3490 2651 225 316 -56 C +ATOM 870 CG2 ILE A 111 12.008 28.379 35.492 1.00 29.81 C +ANISOU 870 CG2 ILE A 111 5352 3416 2557 317 284 -6 C +ATOM 871 CD1 ILE A 111 13.732 30.224 38.342 1.00 31.01 C +ANISOU 871 CD1 ILE A 111 5641 3516 2626 149 298 -56 C +ATOM 872 N GLN A 112 12.215 25.149 36.728 1.00 30.10 N +ANISOU 872 N GLN A 112 5384 3545 2504 299 289 -12 N +ATOM 873 CA GLN A 112 12.223 23.843 36.086 1.00 30.13 C +ANISOU 873 CA GLN A 112 5363 3578 2504 333 267 6 C +ATOM 874 C GLN A 112 11.302 23.878 34.891 1.00 29.23 C +ANISOU 874 C GLN A 112 5216 3457 2433 379 269 2 C +ATOM 875 O GLN A 112 10.077 23.829 35.052 1.00 28.53 O +ANISOU 875 O GLN A 112 5113 3343 2383 385 291 -30 O +ATOM 876 CB GLN A 112 11.771 22.777 37.100 1.00 31.75 C +ANISOU 876 CB GLN A 112 5607 3777 2679 302 277 -8 C +ATOM 877 CG GLN A 112 12.804 22.588 38.211 1.00 33.38 C +ANISOU 877 CG GLN A 112 5866 3984 2831 252 237 11 C +ATOM 878 CD GLN A 112 12.211 22.116 39.523 1.00 35.14 C +ANISOU 878 CD GLN A 112 6173 4182 2993 184 262 -6 C +ATOM 879 OE1 GLN A 112 11.926 20.936 39.693 1.00 37.89 O +ANISOU 879 OE1 GLN A 112 6549 4524 3322 176 248 5 O +ATOM 880 NE2 GLN A 112 12.049 23.040 40.473 1.00 36.08 N +ANISOU 880 NE2 GLN A 112 6351 4282 3074 124 303 -38 N +ATOM 881 N MET A 113 11.886 23.975 33.692 1.00 28.48 N +ANISOU 881 N MET A 113 5109 3380 2330 404 245 32 N +ATOM 882 CA MET A 113 11.103 24.057 32.460 1.00 28.43 C +ANISOU 882 CA MET A 113 5099 3361 2342 436 222 38 C +ATOM 883 C MET A 113 10.338 22.790 32.129 1.00 27.48 C +ANISOU 883 C MET A 113 4967 3245 2226 457 207 22 C +ATOM 884 O MET A 113 9.297 22.857 31.491 1.00 26.96 O +ANISOU 884 O MET A 113 4890 3155 2196 475 176 16 O +ATOM 885 CB MET A 113 11.986 24.401 31.247 1.00 29.01 C +ANISOU 885 CB MET A 113 5193 3455 2374 433 212 73 C +ATOM 886 CG MET A 113 12.706 25.736 31.357 1.00 29.50 C +ANISOU 886 CG MET A 113 5270 3505 2433 399 221 97 C +ATOM 887 SD MET A 113 11.559 27.122 31.445 1.00 30.18 S +ANISOU 887 SD MET A 113 5377 3511 2579 408 187 96 S +ATOM 888 CE MET A 113 10.685 26.906 29.882 1.00 30.15 C +ANISOU 888 CE MET A 113 5401 3485 2567 438 120 124 C +ATOM 889 N ARG A 114 10.854 21.646 32.556 1.00 27.03 N +ANISOU 889 N ARG A 114 4915 3209 2143 454 216 17 N +ATOM 890 CA ARG A 114 10.224 20.357 32.220 1.00 27.72 C +ANISOU 890 CA ARG A 114 5006 3291 2232 467 199 2 C +ATOM 891 C ARG A 114 9.055 20.020 33.152 1.00 28.29 C +ANISOU 891 C ARG A 114 5066 3340 2341 439 217 -23 C +ATOM 892 O ARG A 114 9.258 19.834 34.336 1.00 28.66 O +ANISOU 892 O ARG A 114 5134 3384 2371 403 246 -27 O +ATOM 893 CB ARG A 114 11.248 19.225 32.301 1.00 27.27 C +ANISOU 893 CB ARG A 114 4965 3249 2147 479 195 6 C +ATOM 894 CG ARG A 114 10.698 17.916 31.806 1.00 27.51 C +ANISOU 894 CG ARG A 114 5014 3262 2177 493 174 -11 C +ATOM 895 CD ARG A 114 11.658 16.755 32.007 1.00 27.94 C +ANISOU 895 CD ARG A 114 5084 3306 2225 516 162 -13 C +ATOM 896 NE ARG A 114 12.960 17.029 31.408 1.00 28.34 N +ANISOU 896 NE ARG A 114 5108 3385 2273 548 180 -15 N +ATOM 897 CZ ARG A 114 13.931 16.140 31.277 1.00 28.35 C +ANISOU 897 CZ ARG A 114 5096 3378 2298 588 176 -32 C +ATOM 898 NH1 ARG A 114 13.757 14.892 31.705 1.00 28.84 N +ANISOU 898 NH1 ARG A 114 5187 3391 2379 603 137 -38 N +ATOM 899 NH2 ARG A 114 15.087 16.510 30.728 1.00 28.50 N +ANISOU 899 NH2 ARG A 114 5068 3429 2331 609 215 -44 N +ATOM 900 N PRO A 115 7.836 19.869 32.616 1.00 28.98 N +ANISOU 900 N PRO A 115 5124 3411 2477 444 199 -42 N +ATOM 901 CA PRO A 115 6.762 19.491 33.522 1.00 29.36 C +ANISOU 901 CA PRO A 115 5143 3441 2570 405 239 -76 C +ATOM 902 C PRO A 115 6.935 18.079 34.096 1.00 30.06 C +ANISOU 902 C PRO A 115 5280 3527 2615 368 248 -72 C +ATOM 903 O PRO A 115 7.588 17.216 33.490 1.00 30.30 O +ANISOU 903 O PRO A 115 5346 3558 2608 392 204 -53 O +ATOM 904 CB PRO A 115 5.514 19.547 32.632 1.00 29.68 C +ANISOU 904 CB PRO A 115 5122 3463 2692 423 196 -94 C +ATOM 905 CG PRO A 115 5.959 19.970 31.270 1.00 29.39 C +ANISOU 905 CG PRO A 115 5110 3428 2626 466 121 -61 C +ATOM 906 CD PRO A 115 7.422 19.838 31.201 1.00 28.86 C +ANISOU 906 CD PRO A 115 5105 3389 2469 473 138 -34 C +ATOM 907 N ALA A 116 6.332 17.846 35.251 1.00 31.01 N +ANISOU 907 N ALA A 116 5408 3635 2739 306 308 -94 N +ATOM 908 CA ALA A 116 6.343 16.533 35.870 1.00 32.02 C +ANISOU 908 CA ALA A 116 5599 3745 2823 253 310 -83 C +ATOM 909 C ALA A 116 5.438 15.580 35.090 1.00 32.78 C +ANISOU 909 C ALA A 116 5665 3823 2963 248 281 -96 C +ATOM 910 O ALA A 116 4.383 15.993 34.560 1.00 34.62 O +ANISOU 910 O ALA A 116 5815 4061 3279 253 285 -128 O +ATOM 911 CB ALA A 116 5.873 16.635 37.321 1.00 32.46 C +ANISOU 911 CB ALA A 116 5691 3790 2850 163 397 -103 C +ATOM 912 N LEU A 117 5.845 14.315 35.039 1.00 32.73 N +ANISOU 912 N LEU A 117 5729 3791 2916 238 239 -74 N +ATOM 913 CA LEU A 117 5.100 13.257 34.354 1.00 33.11 C +ANISOU 913 CA LEU A 117 5774 3811 2994 221 202 -86 C +ATOM 914 C LEU A 117 4.150 12.441 35.235 1.00 34.11 C +ANISOU 914 C LEU A 117 5922 3907 3128 116 250 -96 C +ATOM 915 O LEU A 117 3.182 11.867 34.707 1.00 35.63 O +ANISOU 915 O LEU A 117 6074 4084 3376 85 234 -119 O +ATOM 916 CB LEU A 117 6.075 12.279 33.720 1.00 33.33 C +ANISOU 916 CB LEU A 117 5872 3810 2980 271 133 -67 C +ATOM 917 CG LEU A 117 6.475 12.517 32.269 1.00 33.58 C +ANISOU 917 CG LEU A 117 5885 3860 3013 348 87 -80 C +ATOM 918 CD1 LEU A 117 7.484 11.451 31.880 1.00 33.53 C +ANISOU 918 CD1 LEU A 117 5948 3817 2975 392 50 -80 C +ATOM 919 CD2 LEU A 117 5.261 12.391 31.366 1.00 34.28 C +ANISOU 919 CD2 LEU A 117 5936 3944 3145 328 53 -107 C +ATOM 920 N LYS A 118 4.409 12.367 36.547 1.00 33.62 N +ANISOU 920 N LYS A 118 5931 3834 3007 50 304 -78 N +ATOM 921 CA LYS A 118 3.701 11.427 37.418 1.00 34.20 C +ANISOU 921 CA LYS A 118 6067 3869 3055 -69 351 -75 C +ATOM 922 C LYS A 118 2.199 11.594 37.453 1.00 33.52 C +ANISOU 922 C LYS A 118 5877 3801 3057 -142 439 -131 C +ATOM 923 O LYS A 118 1.489 10.607 37.607 1.00 34.07 O +ANISOU 923 O LYS A 118 5969 3837 3137 -231 454 -134 O +ATOM 924 CB LYS A 118 4.238 11.487 38.836 1.00 36.02 C +ANISOU 924 CB LYS A 118 6414 4085 3184 -142 393 -43 C +ATOM 925 CG LYS A 118 3.964 12.775 39.568 1.00 37.58 C +ANISOU 925 CG LYS A 118 6572 4329 3378 -171 500 -83 C +ATOM 926 CD LYS A 118 4.246 12.633 41.042 1.00 40.11 C +ANISOU 926 CD LYS A 118 7040 4626 3573 -285 551 -58 C +ATOM 927 CE LYS A 118 4.390 14.023 41.656 1.00 41.48 C +ANISOU 927 CE LYS A 118 7195 4839 3727 -285 630 -98 C +ATOM 928 NZ LYS A 118 4.672 13.913 43.102 1.00 43.75 N +ANISOU 928 NZ LYS A 118 7653 5102 3868 -411 674 -76 N +ATOM 929 N GLY A 119 1.707 12.821 37.323 1.00 32.13 N +ANISOU 929 N GLY A 119 5580 3669 2957 -107 494 -179 N +ATOM 930 CA GLY A 119 0.265 13.053 37.328 1.00 32.63 C +ANISOU 930 CA GLY A 119 5508 3745 3144 -161 574 -244 C +ATOM 931 C GLY A 119 -0.398 12.374 36.144 1.00 32.32 C +ANISOU 931 C GLY A 119 5396 3691 3192 -143 478 -249 C +ATOM 932 O GLY A 119 -1.425 11.703 36.282 1.00 33.54 O +ANISOU 932 O GLY A 119 5499 3832 3412 -235 517 -278 O +ATOM 933 N ALA A 120 0.211 12.541 34.980 1.00 31.20 N +ANISOU 933 N ALA A 120 5261 3550 3044 -36 355 -223 N +ATOM 934 CA ALA A 120 -0.295 11.976 33.751 1.00 31.35 C +ANISOU 934 CA ALA A 120 5241 3552 3119 -17 245 -227 C +ATOM 935 C ALA A 120 -0.197 10.464 33.769 1.00 31.34 C +ANISOU 935 C ALA A 120 5346 3503 3059 -82 213 -206 C +ATOM 936 O ALA A 120 -1.124 9.783 33.407 1.00 31.46 O +ANISOU 936 O ALA A 120 5316 3496 3140 -144 184 -227 O +ATOM 937 CB ALA A 120 0.477 12.537 32.570 1.00 30.58 C +ANISOU 937 CB ALA A 120 5164 3464 2988 96 140 -204 C +ATOM 938 N ILE A 121 0.949 9.949 34.191 1.00 31.30 N +ANISOU 938 N ILE A 121 5479 3474 2940 -67 208 -163 N +ATOM 939 CA ILE A 121 1.141 8.497 34.324 1.00 31.86 C +ANISOU 939 CA ILE A 121 5670 3477 2958 -123 170 -139 C +ATOM 940 C ILE A 121 0.102 7.857 35.236 1.00 32.58 C +ANISOU 940 C ILE A 121 5760 3543 3074 -272 249 -148 C +ATOM 941 O ILE A 121 -0.479 6.852 34.876 1.00 33.49 O +ANISOU 941 O ILE A 121 5895 3612 3218 -335 208 -154 O +ATOM 942 CB ILE A 121 2.558 8.176 34.819 1.00 31.68 C +ANISOU 942 CB ILE A 121 5779 3423 2834 -76 146 -90 C +ATOM 943 CG1 ILE A 121 3.556 8.472 33.687 1.00 31.59 C +ANISOU 943 CG1 ILE A 121 5767 3426 2810 57 72 -93 C +ATOM 944 CG2 ILE A 121 2.701 6.724 35.228 1.00 32.49 C +ANISOU 944 CG2 ILE A 121 6014 3436 2894 -141 108 -59 C +ATOM 945 CD1 ILE A 121 4.990 8.548 34.176 1.00 31.60 C +ANISOU 945 CD1 ILE A 121 5838 3416 2750 120 58 -57 C +ATOM 946 N LEU A 122 -0.150 8.445 36.400 1.00 32.59 N +ANISOU 946 N LEU A 122 5744 3574 3061 -340 371 -154 N +ATOM 947 CA LEU A 122 -1.132 7.885 37.335 1.00 33.51 C +ANISOU 947 CA LEU A 122 5868 3673 3189 -504 480 -170 C +ATOM 948 C LEU A 122 -2.536 7.921 36.784 1.00 34.11 C +ANISOU 948 C LEU A 122 5769 3771 3417 -553 506 -233 C +ATOM 949 O LEU A 122 -3.297 6.990 37.001 1.00 35.50 O +ANISOU 949 O LEU A 122 5956 3912 3619 -680 535 -239 O +ATOM 950 CB LEU A 122 -1.076 8.585 38.681 1.00 33.62 C +ANISOU 950 CB LEU A 122 5915 3717 3140 -572 622 -177 C +ATOM 951 CG LEU A 122 0.200 8.351 39.500 1.00 33.32 C +ANISOU 951 CG LEU A 122 6073 3642 2942 -570 588 -105 C +ATOM 952 CD1 LEU A 122 0.264 9.335 40.661 1.00 33.45 C +ANISOU 952 CD1 LEU A 122 6111 3700 2895 -622 718 -126 C +ATOM 953 CD2 LEU A 122 0.320 6.922 40.000 1.00 34.21 C +ANISOU 953 CD2 LEU A 122 6360 3668 2968 -680 547 -45 C +ATOM 954 N SER A 123 -2.887 8.992 36.093 1.00 33.54 N +ANISOU 954 N SER A 123 5537 3749 3455 -459 485 -276 N +ATOM 955 CA SER A 123 -4.188 9.069 35.432 1.00 34.64 C +ANISOU 955 CA SER A 123 5492 3901 3767 -485 466 -333 C +ATOM 956 C SER A 123 -4.367 7.983 34.368 1.00 34.76 C +ANISOU 956 C SER A 123 5544 3870 3794 -496 319 -315 C +ATOM 957 O SER A 123 -5.443 7.406 34.256 1.00 36.17 O +ANISOU 957 O SER A 123 5633 4032 4075 -597 322 -347 O +ATOM 958 CB SER A 123 -4.377 10.415 34.754 1.00 34.61 C +ANISOU 958 CB SER A 123 5336 3939 3874 -361 422 -366 C +ATOM 959 OG SER A 123 -4.757 11.369 35.709 1.00 35.64 O +ANISOU 959 OG SER A 123 5373 4103 4063 -380 576 -417 O +ATOM 960 N LEU A 124 -3.334 7.713 33.577 1.00 33.51 N +ANISOU 960 N LEU A 124 5510 3685 3535 -397 196 -273 N +ATOM 961 CA LEU A 124 -3.453 6.671 32.560 1.00 34.18 C +ANISOU 961 CA LEU A 124 5653 3717 3616 -408 65 -268 C +ATOM 962 C LEU A 124 -3.414 5.262 33.122 1.00 34.13 C +ANISOU 962 C LEU A 124 5783 3636 3546 -522 83 -244 C +ATOM 963 O LEU A 124 -4.037 4.388 32.564 1.00 34.90 O +ANISOU 963 O LEU A 124 5884 3687 3686 -589 12 -259 O +ATOM 964 CB LEU A 124 -2.424 6.821 31.446 1.00 33.92 C +ANISOU 964 CB LEU A 124 5708 3677 3501 -274 -52 -249 C +ATOM 965 CG LEU A 124 -2.901 7.910 30.487 1.00 34.77 C +ANISOU 965 CG LEU A 124 5686 3831 3693 -202 -128 -273 C +ATOM 966 CD1 LEU A 124 -1.718 8.507 29.773 1.00 34.50 C +ANISOU 966 CD1 LEU A 124 5736 3813 3558 -77 -177 -249 C +ATOM 967 CD2 LEU A 124 -3.914 7.387 29.492 1.00 36.04 C +ANISOU 967 CD2 LEU A 124 5791 3963 3937 -252 -253 -300 C +ATOM 968 N LEU A 125 -2.703 5.046 34.220 1.00 33.18 N +ANISOU 968 N LEU A 125 5784 3497 3324 -551 164 -203 N +ATOM 969 CA LEU A 125 -2.773 3.769 34.905 1.00 33.65 C +ANISOU 969 CA LEU A 125 5983 3475 3327 -678 183 -170 C +ATOM 970 C LEU A 125 -4.195 3.536 35.372 1.00 35.09 C +ANISOU 970 C LEU A 125 6056 3667 3606 -847 278 -206 C +ATOM 971 O LEU A 125 -4.735 2.455 35.195 1.00 36.20 O +ANISOU 971 O LEU A 125 6241 3743 3769 -954 240 -204 O +ATOM 972 CB LEU A 125 -1.767 3.666 36.039 1.00 32.84 C +ANISOU 972 CB LEU A 125 6038 3343 3095 -684 231 -111 C +ATOM 973 CG LEU A 125 -0.294 3.686 35.570 1.00 31.50 C +ANISOU 973 CG LEU A 125 5968 3148 2853 -522 126 -78 C +ATOM 974 CD1 LEU A 125 0.670 3.789 36.720 1.00 31.22 C +ANISOU 974 CD1 LEU A 125 6055 3092 2713 -522 155 -19 C +ATOM 975 CD2 LEU A 125 0.100 2.477 34.751 1.00 31.86 C +ANISOU 975 CD2 LEU A 125 6120 3095 2888 -486 2 -72 C +ATOM 976 N SER A 126 -4.833 4.565 35.887 1.00 35.49 N +ANISOU 976 N SER A 126 5951 3798 3734 -870 402 -249 N +ATOM 977 CA SER A 126 -6.211 4.437 36.341 1.00 37.23 C +ANISOU 977 CA SER A 126 6031 4039 4076 -1029 519 -301 C +ATOM 978 C SER A 126 -7.201 4.278 35.172 1.00 37.93 C +ANISOU 978 C SER A 126 5949 4130 4333 -1028 410 -349 C +ATOM 979 O SER A 126 -8.073 3.423 35.222 1.00 38.88 O +ANISOU 979 O SER A 126 6036 4215 4518 -1175 424 -365 O +ATOM 980 CB SER A 126 -6.580 5.616 37.250 1.00 37.41 C +ANISOU 980 CB SER A 126 5929 4138 4144 -1045 700 -351 C +ATOM 981 OG SER A 126 -7.953 5.594 37.578 1.00 39.34 O +ANISOU 981 OG SER A 126 5993 4409 4542 -1183 827 -423 O +ATOM 982 N TYR A 127 -7.033 5.076 34.115 1.00 37.66 N +ANISOU 982 N TYR A 127 5823 4129 4357 -873 288 -365 N +ATOM 983 CA TYR A 127 -7.942 5.051 32.952 1.00 38.80 C +ANISOU 983 CA TYR A 127 5814 4272 4653 -865 150 -404 C +ATOM 984 C TYR A 127 -7.908 3.722 32.189 1.00 39.25 C +ANISOU 984 C TYR A 127 6003 4249 4660 -920 10 -382 C +ATOM 985 O TYR A 127 -8.941 3.248 31.759 1.00 40.36 O +ANISOU 985 O TYR A 127 6037 4372 4925 -1015 -49 -416 O +ATOM 986 CB TYR A 127 -7.622 6.201 31.994 1.00 38.29 C +ANISOU 986 CB TYR A 127 5677 4247 4623 -692 34 -409 C +ATOM 987 CG TYR A 127 -8.338 6.117 30.658 1.00 39.32 C +ANISOU 987 CG TYR A 127 5714 4361 4865 -674 -158 -429 C +ATOM 988 CD1 TYR A 127 -9.667 6.507 30.529 1.00 41.15 C +ANISOU 988 CD1 TYR A 127 5699 4614 5320 -724 -177 -484 C +ATOM 989 CD2 TYR A 127 -7.681 5.641 29.535 1.00 39.04 C +ANISOU 989 CD2 TYR A 127 5836 4284 4713 -612 -322 -400 C +ATOM 990 CE1 TYR A 127 -10.326 6.432 29.308 1.00 42.39 C +ANISOU 990 CE1 TYR A 127 5777 4748 5579 -713 -385 -496 C +ATOM 991 CE2 TYR A 127 -8.322 5.536 28.312 1.00 40.28 C +ANISOU 991 CE2 TYR A 127 5941 4420 4944 -612 -511 -417 C +ATOM 992 CZ TYR A 127 -9.643 5.939 28.196 1.00 42.04 C +ANISOU 992 CZ TYR A 127 5925 4661 5385 -664 -557 -458 C +ATOM 993 OH TYR A 127 -10.260 5.850 26.957 1.00 43.74 O +ANISOU 993 OH TYR A 127 6098 4848 5670 -666 -778 -467 O +ATOM 994 N TYR A 128 -6.718 3.151 32.017 1.00 38.75 N +ANISOU 994 N TYR A 128 6162 4133 4427 -855 -44 -334 N +ATOM 995 CA TYR A 128 -6.540 1.819 31.447 1.00 39.88 C +ANISOU 995 CA TYR A 128 6464 4181 4508 -903 -154 -320 C +ATOM 996 C TYR A 128 -6.744 0.670 32.436 1.00 40.42 C +ANISOU 996 C TYR A 128 6643 4175 4537 -1068 -71 -293 C +ATOM 997 O TYR A 128 -6.593 -0.466 32.053 1.00 40.94 O +ANISOU 997 O TYR A 128 6852 4145 4557 -1112 -159 -281 O +ATOM 998 CB TYR A 128 -5.121 1.664 30.893 1.00 39.72 C +ANISOU 998 CB TYR A 128 6629 4122 4339 -757 -232 -291 C +ATOM 999 CG TYR A 128 -4.783 2.472 29.666 1.00 40.31 C +ANISOU 999 CG TYR A 128 6666 4241 4408 -615 -339 -312 C +ATOM 1000 CD1 TYR A 128 -5.723 2.725 28.674 1.00 42.24 C +ANISOU 1000 CD1 TYR A 128 6794 4504 4752 -633 -454 -349 C +ATOM 1001 CD2 TYR A 128 -3.494 2.913 29.463 1.00 40.00 C +ANISOU 1001 CD2 TYR A 128 6723 4215 4258 -475 -338 -292 C +ATOM 1002 CE1 TYR A 128 -5.392 3.441 27.551 1.00 43.01 C +ANISOU 1002 CE1 TYR A 128 6893 4630 4817 -520 -562 -357 C +ATOM 1003 CE2 TYR A 128 -3.139 3.613 28.322 1.00 40.41 C +ANISOU 1003 CE2 TYR A 128 6767 4302 4282 -365 -424 -308 C +ATOM 1004 CZ TYR A 128 -4.087 3.876 27.381 1.00 42.24 C +ANISOU 1004 CZ TYR A 128 6907 4548 4591 -391 -535 -336 C +ATOM 1005 OH TYR A 128 -3.738 4.590 26.252 1.00 44.58 O +ANISOU 1005 OH TYR A 128 7226 4873 4838 -298 -629 -342 O +ATOM 1006 N LYS A 129 -7.055 0.968 33.699 1.00 40.55 N +ANISOU 1006 N LYS A 129 6616 4229 4563 -1163 99 -284 N +ATOM 1007 CA LYS A 129 -7.249 -0.022 34.744 1.00 41.41 C +ANISOU 1007 CA LYS A 129 6850 4269 4613 -1340 193 -249 C +ATOM 1008 C LYS A 129 -6.081 -0.983 34.946 1.00 40.44 C +ANISOU 1008 C LYS A 129 7001 4034 4329 -1310 122 -178 C +ATOM 1009 O LYS A 129 -6.283 -2.164 35.196 1.00 41.42 O +ANISOU 1009 O LYS A 129 7259 4055 4423 -1442 100 -149 O +ATOM 1010 CB LYS A 129 -8.539 -0.775 34.493 1.00 43.66 C +ANISOU 1010 CB LYS A 129 7038 4524 5024 -1514 184 -286 C +ATOM 1011 CG LYS A 129 -9.772 0.101 34.636 1.00 45.13 C +ANISOU 1011 CG LYS A 129 6936 4812 5397 -1575 290 -358 C +ATOM 1012 CD LYS A 129 -10.920 -0.672 35.277 1.00 47.82 C +ANISOU 1012 CD LYS A 129 7215 5129 5823 -1820 405 -380 C +ATOM 1013 CE LYS A 129 -12.181 0.159 35.402 1.00 49.53 C +ANISOU 1013 CE LYS A 129 7111 5443 6264 -1877 520 -468 C +ATOM 1014 NZ LYS A 129 -12.724 0.536 34.057 1.00 49.99 N +ANISOU 1014 NZ LYS A 129 6974 5523 6495 -1775 327 -515 N +ATOM 1015 N TRP A 130 -4.860 -0.470 34.879 1.00 38.65 N +ANISOU 1015 N TRP A 130 6852 3820 4013 -1141 84 -151 N +ATOM 1016 CA TRP A 130 -3.664 -1.285 35.088 1.00 38.45 C +ANISOU 1016 CA TRP A 130 7057 3687 3864 -1086 8 -90 C +ATOM 1017 C TRP A 130 -3.490 -1.585 36.561 1.00 39.85 C +ANISOU 1017 C TRP A 130 7371 3823 3946 -1211 105 -22 C +ATOM 1018 O TRP A 130 -3.002 -0.753 37.322 1.00 39.85 O +ANISOU 1018 O TRP A 130 7368 3884 3886 -1173 182 -1 O +ATOM 1019 CB TRP A 130 -2.405 -0.565 34.592 1.00 36.42 C +ANISOU 1019 CB TRP A 130 6811 3465 3560 -872 -50 -88 C +ATOM 1020 CG TRP A 130 -2.183 -0.594 33.069 1.00 35.45 C +ANISOU 1020 CG TRP A 130 6655 3340 3474 -743 -172 -140 C +ATOM 1021 CD1 TRP A 130 -3.140 -0.652 32.117 1.00 35.74 C +ANISOU 1021 CD1 TRP A 130 6591 3395 3594 -783 -225 -194 C +ATOM 1022 CD2 TRP A 130 -0.932 -0.501 32.376 1.00 33.78 C +ANISOU 1022 CD2 TRP A 130 6513 3111 3210 -569 -245 -146 C +ATOM 1023 NE1 TRP A 130 -2.571 -0.627 30.887 1.00 35.02 N +ANISOU 1023 NE1 TRP A 130 6530 3293 3480 -653 -328 -229 N +ATOM 1024 CE2 TRP A 130 -1.216 -0.530 31.018 1.00 33.82 C +ANISOU 1024 CE2 TRP A 130 6478 3123 3248 -522 -327 -206 C +ATOM 1025 CE3 TRP A 130 0.393 -0.426 32.787 1.00 33.06 C +ANISOU 1025 CE3 TRP A 130 6513 2994 3052 -458 -249 -110 C +ATOM 1026 CZ2 TRP A 130 -0.227 -0.493 30.039 1.00 33.30 C +ANISOU 1026 CZ2 TRP A 130 6470 3044 3135 -375 -388 -237 C +ATOM 1027 CZ3 TRP A 130 1.385 -0.397 31.829 1.00 32.51 C +ANISOU 1027 CZ3 TRP A 130 6473 2913 2966 -303 -311 -144 C +ATOM 1028 CH2 TRP A 130 1.069 -0.421 30.466 1.00 32.64 C +ANISOU 1028 CH2 TRP A 130 6457 2941 3001 -266 -366 -210 C +ATOM 1029 N GLU A 131 -3.902 -2.761 36.980 1.00 42.12 N +ANISOU 1029 N GLU A 131 7792 4002 4209 -1372 97 12 N +ATOM 1030 CA GLU A 131 -3.759 -3.155 38.374 1.00 44.20 C +ANISOU 1030 CA GLU A 131 8227 4208 4358 -1518 175 89 C +ATOM 1031 C GLU A 131 -2.671 -4.206 38.560 1.00 44.61 C +ANISOU 1031 C GLU A 131 8534 4097 4316 -1473 29 170 C +ATOM 1032 O GLU A 131 -2.284 -4.521 39.675 1.00 45.62 O +ANISOU 1032 O GLU A 131 8842 4159 4331 -1561 44 252 O +ATOM 1033 CB GLU A 131 -5.078 -3.698 38.899 1.00 46.59 C +ANISOU 1033 CB GLU A 131 8510 4497 4693 -1771 293 80 C +ATOM 1034 CG GLU A 131 -6.225 -2.716 38.773 1.00 46.98 C +ANISOU 1034 CG GLU A 131 8282 4695 4870 -1820 440 -9 C +ATOM 1035 CD GLU A 131 -7.572 -3.369 38.996 1.00 49.73 C +ANISOU 1035 CD GLU A 131 8567 5026 5299 -2060 537 -37 C +ATOM 1036 OE1 GLU A 131 -7.686 -4.627 39.167 1.00 51.04 O +ANISOU 1036 OE1 GLU A 131 8912 5062 5416 -2202 485 14 O +ATOM 1037 OE2 GLU A 131 -8.531 -2.580 38.986 1.00 51.00 O +ANISOU 1037 OE2 GLU A 131 8485 5303 5589 -2103 666 -117 O +ATOM 1038 N LYS A 132 -2.167 -4.722 37.455 1.00 44.30 N +ANISOU 1038 N LYS A 132 8513 3990 4328 -1331 -115 144 N +ATOM 1039 CA LYS A 132 -1.088 -5.674 37.488 1.00 45.04 C +ANISOU 1039 CA LYS A 132 8815 3923 4373 -1250 -260 200 C +ATOM 1040 C LYS A 132 -0.207 -5.334 36.310 1.00 42.71 C +ANISOU 1040 C LYS A 132 8442 3652 4130 -1011 -350 139 C +ATOM 1041 O LYS A 132 -0.692 -5.366 35.164 1.00 42.77 O +ANISOU 1041 O LYS A 132 8350 3688 4210 -977 -373 61 O +ATOM 1042 CB LYS A 132 -1.649 -7.085 37.354 1.00 47.51 C +ANISOU 1042 CB LYS A 132 9271 4078 4703 -1391 -328 217 C +ATOM 1043 CG LYS A 132 -0.584 -8.149 37.193 1.00 49.07 C +ANISOU 1043 CG LYS A 132 9673 4084 4887 -1285 -496 256 C +ATOM 1044 CD LYS A 132 -1.201 -9.463 36.686 1.00 51.28 C +ANISOU 1044 CD LYS A 132 10063 4210 5211 -1394 -573 241 C +ATOM 1045 CE LYS A 132 -0.120 -10.450 36.275 1.00 52.08 C +ANISOU 1045 CE LYS A 132 10336 4119 5334 -1245 -742 247 C +ATOM 1046 NZ LYS A 132 -0.672 -11.823 36.215 1.00 54.81 N +ANISOU 1046 NZ LYS A 132 10853 4275 5694 -1392 -819 265 N +ATOM 1047 N PHE A 133 1.052 -4.985 36.582 1.00 40.78 N +ANISOU 1047 N PHE A 133 8242 3400 3850 -859 -397 171 N +ATOM 1048 CA PHE A 133 1.985 -4.600 35.527 1.00 39.32 C +ANISOU 1048 CA PHE A 133 7980 3247 3712 -639 -455 109 C +ATOM 1049 C PHE A 133 3.436 -4.592 35.962 1.00 39.29 C +ANISOU 1049 C PHE A 133 8053 3185 3689 -496 -530 155 C +ATOM 1050 O PHE A 133 3.718 -4.627 37.141 1.00 40.13 O +ANISOU 1050 O PHE A 133 8258 3253 3733 -561 -542 241 O +ATOM 1051 CB PHE A 133 1.631 -3.237 34.937 1.00 37.30 C +ANISOU 1051 CB PHE A 133 7514 3176 3481 -584 -363 48 C +ATOM 1052 CG PHE A 133 1.742 -2.081 35.908 1.00 36.04 C +ANISOU 1052 CG PHE A 133 7285 3132 3276 -601 -267 86 C +ATOM 1053 CD1 PHE A 133 0.662 -1.714 36.685 1.00 36.39 C +ANISOU 1053 CD1 PHE A 133 7281 3240 3305 -769 -151 99 C +ATOM 1054 CD2 PHE A 133 2.898 -1.327 35.986 1.00 34.70 C +ANISOU 1054 CD2 PHE A 133 7087 3009 3087 -452 -282 97 C +ATOM 1055 CE1 PHE A 133 0.733 -0.630 37.552 1.00 35.81 C +ANISOU 1055 CE1 PHE A 133 7152 3268 3186 -787 -50 117 C +ATOM 1056 CE2 PHE A 133 2.975 -0.235 36.832 1.00 34.07 C +ANISOU 1056 CE2 PHE A 133 6951 3030 2962 -473 -198 124 C +ATOM 1057 CZ PHE A 133 1.894 0.110 37.632 1.00 34.55 C +ANISOU 1057 CZ PHE A 133 6983 3147 2997 -639 -81 132 C +ATOM 1058 N VAL A 134 4.335 -4.533 34.983 1.00 38.96 N +ANISOU 1058 N VAL A 134 7962 3138 3702 -308 -581 92 N +ATOM 1059 CA VAL A 134 5.758 -4.515 35.214 1.00 39.11 C +ANISOU 1059 CA VAL A 134 8010 3105 3742 -151 -654 114 C +ATOM 1060 C VAL A 134 6.193 -3.094 35.110 1.00 38.09 C +ANISOU 1060 C VAL A 134 7722 3147 3603 -65 -576 93 C +ATOM 1061 O VAL A 134 5.693 -2.332 34.285 1.00 37.77 O +ANISOU 1061 O VAL A 134 7552 3230 3567 -51 -497 29 O +ATOM 1062 CB VAL A 134 6.534 -5.294 34.137 1.00 39.96 C +ANISOU 1062 CB VAL A 134 8142 3105 3933 6 -729 35 C +ATOM 1063 CG1 VAL A 134 8.042 -5.272 34.411 1.00 40.17 C +ANISOU 1063 CG1 VAL A 134 8166 3077 4018 175 -802 50 C +ATOM 1064 CG2 VAL A 134 6.058 -6.738 34.071 1.00 41.71 C +ANISOU 1064 CG2 VAL A 134 8528 3143 4176 -73 -811 39 C +ATOM 1065 N TYR A 135 7.161 -2.728 35.920 1.00 38.29 N +ANISOU 1065 N TYR A 135 7761 3168 3617 -6 -615 151 N +ATOM 1066 CA TYR A 135 7.652 -1.388 35.919 1.00 37.06 C +ANISOU 1066 CA TYR A 135 7467 3161 3451 66 -550 138 C +ATOM 1067 C TYR A 135 9.159 -1.456 35.845 1.00 37.44 C +ANISOU 1067 C TYR A 135 7498 3158 3567 234 -635 136 C +ATOM 1068 O TYR A 135 9.831 -1.819 36.818 1.00 38.35 O +ANISOU 1068 O TYR A 135 7705 3182 3684 237 -737 213 O +ATOM 1069 CB TYR A 135 7.170 -0.698 37.179 1.00 37.06 C +ANISOU 1069 CB TYR A 135 7491 3227 3362 -70 -494 211 C +ATOM 1070 CG TYR A 135 7.773 0.658 37.397 1.00 36.43 C +ANISOU 1070 CG TYR A 135 7297 3276 3266 -4 -445 209 C +ATOM 1071 CD1 TYR A 135 7.722 1.630 36.413 1.00 35.06 C +ANISOU 1071 CD1 TYR A 135 6965 3228 3126 75 -366 136 C +ATOM 1072 CD2 TYR A 135 8.369 0.977 38.608 1.00 36.75 C +ANISOU 1072 CD2 TYR A 135 7407 3305 3249 -37 -487 286 C +ATOM 1073 CE1 TYR A 135 8.264 2.879 36.631 1.00 34.54 C +ANISOU 1073 CE1 TYR A 135 6807 3270 3047 124 -323 138 C +ATOM 1074 CE2 TYR A 135 8.906 2.224 38.830 1.00 35.99 C +ANISOU 1074 CE2 TYR A 135 7216 3321 3138 11 -446 281 C +ATOM 1075 CZ TYR A 135 8.856 3.174 37.851 1.00 34.92 C +ANISOU 1075 CZ TYR A 135 6916 3304 3045 92 -360 207 C +ATOM 1076 OH TYR A 135 9.403 4.420 38.105 1.00 34.29 O +ANISOU 1076 OH TYR A 135 6753 3323 2950 131 -324 207 O +ATOM 1077 N LEU A 136 9.683 -1.138 34.667 1.00 36.86 N +ANISOU 1077 N LEU A 136 7311 3137 3554 368 -596 45 N +ATOM 1078 CA LEU A 136 11.114 -1.129 34.439 1.00 37.51 C +ANISOU 1078 CA LEU A 136 7336 3188 3726 533 -646 18 C +ATOM 1079 C LEU A 136 11.557 0.305 34.568 1.00 36.48 C +ANISOU 1079 C LEU A 136 7073 3214 3572 562 -576 24 C +ATOM 1080 O LEU A 136 10.960 1.167 33.949 1.00 35.54 O +ANISOU 1080 O LEU A 136 6875 3221 3407 532 -471 -15 O +ATOM 1081 CB LEU A 136 11.445 -1.638 33.042 1.00 37.87 C +ANISOU 1081 CB LEU A 136 7346 3199 3843 648 -616 -97 C +ATOM 1082 CG LEU A 136 10.917 -3.017 32.647 1.00 39.38 C +ANISOU 1082 CG LEU A 136 7667 3238 4055 621 -670 -130 C +ATOM 1083 CD1 LEU A 136 11.248 -3.317 31.199 1.00 39.83 C +ANISOU 1083 CD1 LEU A 136 7689 3284 4159 727 -614 -263 C +ATOM 1084 CD2 LEU A 136 11.492 -4.114 33.537 1.00 41.04 C +ANISOU 1084 CD2 LEU A 136 7997 3259 4337 648 -817 -66 C +ATOM 1085 N TYR A 137 12.601 0.567 35.350 1.00 37.60 N +ANISOU 1085 N TYR A 137 7193 3339 3753 617 -648 74 N +ATOM 1086 CA TYR A 137 13.020 1.955 35.603 1.00 37.34 C +ANISOU 1086 CA TYR A 137 7048 3446 3693 625 -591 86 C +ATOM 1087 C TYR A 137 14.519 2.098 35.763 1.00 38.17 C +ANISOU 1087 C TYR A 137 7070 3528 3904 752 -666 86 C +ATOM 1088 O TYR A 137 15.210 1.154 36.146 1.00 39.54 O +ANISOU 1088 O TYR A 137 7293 3563 4165 815 -797 111 O +ATOM 1089 CB TYR A 137 12.313 2.516 36.849 1.00 37.16 C +ANISOU 1089 CB TYR A 137 7098 3465 3556 476 -586 173 C +ATOM 1090 CG TYR A 137 12.758 1.848 38.120 1.00 38.85 C +ANISOU 1090 CG TYR A 137 7447 3557 3756 435 -731 269 C +ATOM 1091 CD1 TYR A 137 12.227 0.621 38.509 1.00 40.43 C +ANISOU 1091 CD1 TYR A 137 7807 3619 3934 361 -805 313 C +ATOM 1092 CD2 TYR A 137 13.733 2.422 38.939 1.00 39.70 C +ANISOU 1092 CD2 TYR A 137 7537 3676 3870 461 -812 322 C +ATOM 1093 CE1 TYR A 137 12.647 -0.012 39.677 1.00 41.94 C +ANISOU 1093 CE1 TYR A 137 8152 3682 4101 314 -959 414 C +ATOM 1094 CE2 TYR A 137 14.154 1.796 40.110 1.00 41.37 C +ANISOU 1094 CE2 TYR A 137 7893 3763 4059 415 -975 420 C +ATOM 1095 CZ TYR A 137 13.608 0.574 40.474 1.00 42.67 C +ANISOU 1095 CZ TYR A 137 8231 3786 4193 342 -1050 469 C +ATOM 1096 OH TYR A 137 14.028 -0.062 41.641 1.00 44.91 O +ANISOU 1096 OH TYR A 137 8687 3932 4442 287 -1231 580 O +ATOM 1097 N ASP A 138 15.011 3.288 35.440 1.00 38.22 N +ANISOU 1097 N ASP A 138 6941 3663 3915 789 -587 57 N +ATOM 1098 CA ASP A 138 16.332 3.736 35.880 1.00 40.07 C +ANISOU 1098 CA ASP A 138 7081 3905 4235 867 -655 75 C +ATOM 1099 C ASP A 138 16.132 4.992 36.717 1.00 40.26 C +ANISOU 1099 C ASP A 138 7100 4036 4161 770 -632 136 C +ATOM 1100 O ASP A 138 15.020 5.482 36.846 1.00 39.25 O +ANISOU 1100 O ASP A 138 7023 3972 3917 664 -549 148 O +ATOM 1101 CB ASP A 138 17.309 3.935 34.706 1.00 40.62 C +ANISOU 1101 CB ASP A 138 6992 4017 4424 1002 -579 -26 C +ATOM 1102 CG ASP A 138 16.869 5.048 33.710 1.00 39.64 C +ANISOU 1102 CG ASP A 138 6793 4045 4222 972 -408 -84 C +ATOM 1103 OD1 ASP A 138 16.214 6.026 34.120 1.00 38.99 O +ANISOU 1103 OD1 ASP A 138 6726 4053 4035 877 -369 -38 O +ATOM 1104 OD2 ASP A 138 17.226 4.961 32.511 1.00 39.93 O +ANISOU 1104 OD2 ASP A 138 6762 4105 4304 1045 -315 -179 O +ATOM 1105 N THR A 139 17.195 5.501 37.304 1.00 43.27 N +ANISOU 1105 N THR A 139 7414 4428 4596 806 -708 167 N +ATOM 1106 CA THR A 139 17.073 6.585 38.271 1.00 45.37 C +ANISOU 1106 CA THR A 139 7707 4768 4763 706 -712 228 C +ATOM 1107 C THR A 139 17.529 7.930 37.722 1.00 45.83 C +ANISOU 1107 C THR A 139 7616 4959 4837 732 -608 182 C +ATOM 1108 O THR A 139 17.585 8.909 38.460 1.00 45.69 O +ANISOU 1108 O THR A 139 7607 4998 4754 662 -612 221 O +ATOM 1109 CB THR A 139 17.884 6.254 39.558 1.00 47.82 C +ANISOU 1109 CB THR A 139 8089 4984 5094 692 -907 317 C +ATOM 1110 OG1 THR A 139 19.230 5.886 39.203 1.00 49.35 O +ANISOU 1110 OG1 THR A 139 8150 5126 5472 834 -1003 289 O +ATOM 1111 CG2 THR A 139 17.229 5.085 40.345 1.00 48.85 C +ANISOU 1111 CG2 THR A 139 8423 4982 5155 614 -1010 389 C +ATOM 1112 N GLU A 140 17.816 8.007 36.434 1.00 47.74 N +ANISOU 1112 N GLU A 140 7741 5246 5151 818 -509 100 N +ATOM 1113 CA GLU A 140 18.438 9.211 35.881 1.00 50.35 C +ANISOU 1113 CA GLU A 140 7935 5687 5507 841 -420 62 C +ATOM 1114 C GLU A 140 17.558 10.449 35.817 1.00 48.51 C +ANISOU 1114 C GLU A 140 7721 5557 5153 750 -314 69 C +ATOM 1115 O GLU A 140 18.060 11.551 35.619 1.00 49.30 O +ANISOU 1115 O GLU A 140 7736 5736 5260 745 -263 58 O +ATOM 1116 CB GLU A 140 19.021 8.945 34.491 1.00 53.39 C +ANISOU 1116 CB GLU A 140 8208 6090 5987 942 -327 -32 C +ATOM 1117 CG GLU A 140 20.120 7.891 34.421 1.00 57.95 C +ANISOU 1117 CG GLU A 140 8715 6571 6732 1060 -410 -66 C +ATOM 1118 CD GLU A 140 20.818 7.581 35.762 1.00 63.88 C +ANISOU 1118 CD GLU A 140 9476 7238 7556 1067 -603 13 C +ATOM 1119 OE1 GLU A 140 21.008 8.499 36.623 1.00 64.53 O +ANISOU 1119 OE1 GLU A 140 9557 7370 7590 996 -654 76 O +ATOM 1120 OE2 GLU A 140 21.179 6.374 35.958 1.00 69.97 O +ANISOU 1120 OE2 GLU A 140 10270 7879 8433 1143 -719 14 O +ATOM 1121 N ARG A 141 16.252 10.281 35.958 1.00 47.27 N +ANISOU 1121 N ARG A 141 7666 5393 4899 677 -280 82 N +ATOM 1122 CA ARG A 141 15.343 11.420 36.012 1.00 44.72 C +ANISOU 1122 CA ARG A 141 7355 5150 4487 599 -191 85 C +ATOM 1123 C ARG A 141 14.761 11.572 37.400 1.00 42.65 C +ANISOU 1123 C ARG A 141 7197 4865 4143 496 -228 140 C +ATOM 1124 O ARG A 141 13.684 12.133 37.571 1.00 40.46 O +ANISOU 1124 O ARG A 141 6950 4624 3799 424 -151 133 O +ATOM 1125 CB ARG A 141 14.256 11.287 34.935 1.00 45.14 C +ANISOU 1125 CB ARG A 141 7413 5225 4513 596 -106 40 C +ATOM 1126 CG ARG A 141 14.684 11.822 33.562 1.00 46.72 C +ANISOU 1126 CG ARG A 141 7526 5484 4738 656 -32 -13 C +ATOM 1127 CD ARG A 141 14.192 10.979 32.382 1.00 48.63 C +ANISOU 1127 CD ARG A 141 7794 5702 4980 688 -2 -65 C +ATOM 1128 NE ARG A 141 14.552 9.598 32.667 1.00 51.13 N +ANISOU 1128 NE ARG A 141 8151 5924 5349 730 -71 -70 N +ATOM 1129 CZ ARG A 141 13.701 8.635 32.980 1.00 50.97 C +ANISOU 1129 CZ ARG A 141 8220 5835 5311 692 -115 -57 C +ATOM 1130 NH1 ARG A 141 12.381 8.844 32.962 1.00 51.99 N +ANISOU 1130 NH1 ARG A 141 8389 5986 5378 612 -85 -49 N +ATOM 1131 NH2 ARG A 141 14.180 7.447 33.283 1.00 50.95 N +ANISOU 1131 NH2 ARG A 141 8261 5732 5365 735 -191 -55 N +ATOM 1132 N GLY A 142 15.495 11.089 38.397 1.00 43.88 N +ANISOU 1132 N GLY A 142 7407 4957 4306 486 -348 192 N +ATOM 1133 CA GLY A 142 15.074 11.166 39.789 1.00 44.38 C +ANISOU 1133 CA GLY A 142 7604 4990 4266 371 -390 248 C +ATOM 1134 C GLY A 142 14.182 10.038 40.242 1.00 44.74 C +ANISOU 1134 C GLY A 142 7785 4958 4255 304 -409 276 C +ATOM 1135 O GLY A 142 13.977 9.065 39.536 1.00 43.09 O +ANISOU 1135 O GLY A 142 7571 4701 4100 354 -418 258 O +ATOM 1136 N PHE A 143 13.638 10.217 41.438 1.00 46.89 N +ANISOU 1136 N PHE A 143 8188 5216 4410 176 -405 315 N +ATOM 1137 CA PHE A 143 12.834 9.210 42.132 1.00 49.63 C +ANISOU 1137 CA PHE A 143 8693 5484 4676 71 -420 355 C +ATOM 1138 C PHE A 143 11.364 9.596 42.181 1.00 48.11 C +ANISOU 1138 C PHE A 143 8514 5347 4418 -30 -250 311 C +ATOM 1139 O PHE A 143 10.561 8.890 42.768 1.00 49.72 O +ANISOU 1139 O PHE A 143 8838 5501 4549 -141 -226 334 O +ATOM 1140 CB PHE A 143 13.342 9.021 43.576 1.00 53.22 C +ANISOU 1140 CB PHE A 143 9320 5870 5029 -24 -544 438 C +ATOM 1141 CG PHE A 143 14.820 8.747 43.662 1.00 56.79 C +ANISOU 1141 CG PHE A 143 9744 6265 5569 73 -736 484 C +ATOM 1142 CD1 PHE A 143 15.331 7.492 43.311 1.00 58.91 C +ANISOU 1142 CD1 PHE A 143 10019 6425 5937 160 -867 512 C +ATOM 1143 CD2 PHE A 143 15.707 9.751 44.055 1.00 58.41 C +ANISOU 1143 CD2 PHE A 143 9899 6516 5776 85 -787 491 C +ATOM 1144 CE1 PHE A 143 16.696 7.242 43.360 1.00 60.91 C +ANISOU 1144 CE1 PHE A 143 10214 6620 6309 265 -1043 542 C +ATOM 1145 CE2 PHE A 143 17.076 9.502 44.106 1.00 60.38 C +ANISOU 1145 CE2 PHE A 143 10091 6714 6137 177 -969 527 C +ATOM 1146 CZ PHE A 143 17.568 8.244 43.767 1.00 61.34 C +ANISOU 1146 CZ PHE A 143 10203 6729 6374 272 -1097 552 C +ATOM 1147 N SER A 144 11.016 10.708 41.573 1.00 45.39 N +ANISOU 1147 N SER A 144 8040 5097 4107 4 -138 248 N +ATOM 1148 CA SER A 144 9.665 11.238 41.691 1.00 46.01 C +ANISOU 1148 CA SER A 144 8102 5225 4152 -81 15 198 C +ATOM 1149 C SER A 144 8.585 10.239 41.204 1.00 44.52 C +ANISOU 1149 C SER A 144 7915 5005 3993 -115 58 181 C +ATOM 1150 O SER A 144 7.597 9.977 41.899 1.00 44.48 O +ANISOU 1150 O SER A 144 7982 4987 3929 -243 141 176 O +ATOM 1151 CB SER A 144 9.578 12.572 40.913 1.00 46.86 C +ANISOU 1151 CB SER A 144 8058 5420 4323 -8 94 139 C +ATOM 1152 OG SER A 144 8.362 13.240 41.198 1.00 49.70 O +ANISOU 1152 OG SER A 144 8393 5817 4671 -82 232 86 O +ATOM 1153 N VAL A 145 8.776 9.700 40.003 1.00 42.08 N +ANISOU 1153 N VAL A 145 7529 4685 3772 -11 9 166 N +ATOM 1154 CA VAL A 145 7.826 8.761 39.437 1.00 41.14 C +ANISOU 1154 CA VAL A 145 7411 4533 3688 -40 29 146 C +ATOM 1155 C VAL A 145 7.873 7.424 40.180 1.00 40.84 C +ANISOU 1155 C VAL A 145 7533 4387 3597 -119 -44 206 C +ATOM 1156 O VAL A 145 6.841 6.854 40.491 1.00 39.51 O +ANISOU 1156 O VAL A 145 7419 4191 3401 -234 11 205 O +ATOM 1157 CB VAL A 145 8.080 8.565 37.933 1.00 40.25 C +ANISOU 1157 CB VAL A 145 7198 4430 3664 85 -6 108 C +ATOM 1158 CG1 VAL A 145 7.251 7.417 37.354 1.00 40.28 C +ANISOU 1158 CG1 VAL A 145 7228 4379 3697 53 -18 91 C +ATOM 1159 CG2 VAL A 145 7.784 9.869 37.217 1.00 39.41 C +ANISOU 1159 CG2 VAL A 145 6959 4419 3595 132 65 59 C +ATOM 1160 N LEU A 146 9.067 6.948 40.469 1.00 40.99 N +ANISOU 1160 N LEU A 146 7623 4339 3611 -61 -175 259 N +ATOM 1161 CA LEU A 146 9.218 5.722 41.229 1.00 42.78 C +ANISOU 1161 CA LEU A 146 8021 4443 3790 -131 -277 330 C +ATOM 1162 C LEU A 146 8.386 5.714 42.515 1.00 43.47 C +ANISOU 1162 C LEU A 146 8253 4518 3744 -322 -207 367 C +ATOM 1163 O LEU A 146 7.732 4.747 42.805 1.00 43.98 O +ANISOU 1163 O LEU A 146 8429 4509 3772 -426 -206 395 O +ATOM 1164 CB LEU A 146 10.689 5.484 41.536 1.00 43.53 C +ANISOU 1164 CB LEU A 146 8155 4471 3911 -38 -443 384 C +ATOM 1165 CG LEU A 146 11.046 4.227 42.320 1.00 46.40 C +ANISOU 1165 CG LEU A 146 8705 4683 4242 -87 -597 471 C +ATOM 1166 CD1 LEU A 146 12.515 3.981 42.033 1.00 47.87 C +ANISOU 1166 CD1 LEU A 146 8835 4809 4541 72 -759 488 C +ATOM 1167 CD2 LEU A 146 10.840 4.283 43.830 1.00 47.48 C +ANISOU 1167 CD2 LEU A 146 9036 4784 4219 -259 -620 551 C +ATOM 1168 N GLN A 147 8.415 6.797 43.280 1.00 44.54 N +ANISOU 1168 N GLN A 147 8395 4723 3804 -378 -138 361 N +ATOM 1169 CA GLN A 147 7.722 6.869 44.579 1.00 45.97 C +ANISOU 1169 CA GLN A 147 8732 4896 3837 -571 -51 385 C +ATOM 1170 C GLN A 147 6.229 7.024 44.433 1.00 44.88 C +ANISOU 1170 C GLN A 147 8525 4814 3710 -671 142 313 C +ATOM 1171 O GLN A 147 5.481 6.481 45.218 1.00 46.50 O +ANISOU 1171 O GLN A 147 8861 4981 3823 -839 214 332 O +ATOM 1172 CB GLN A 147 8.270 8.012 45.431 1.00 47.80 C +ANISOU 1172 CB GLN A 147 9001 5178 3982 -598 -37 388 C +ATOM 1173 CG GLN A 147 9.678 7.720 45.918 1.00 50.50 C +ANISOU 1173 CG GLN A 147 9449 5445 4293 -550 -249 475 C +ATOM 1174 CD GLN A 147 10.312 8.858 46.711 1.00 53.12 C +ANISOU 1174 CD GLN A 147 9817 5823 4543 -577 -261 478 C +ATOM 1175 OE1 GLN A 147 11.503 8.778 47.081 1.00 54.71 O +ANISOU 1175 OE1 GLN A 147 10074 5972 4738 -532 -446 544 O +ATOM 1176 NE2 GLN A 147 9.524 9.914 47.008 1.00 53.60 N +ANISOU 1176 NE2 GLN A 147 9844 5971 4548 -653 -72 404 N +ATOM 1177 N ALA A 148 5.790 7.776 43.441 1.00 42.29 N +ANISOU 1177 N ALA A 148 7993 4575 3500 -575 224 232 N +ATOM 1178 CA ALA A 148 4.373 7.910 43.136 1.00 41.88 C +ANISOU 1178 CA ALA A 148 7834 4572 3507 -645 382 158 C +ATOM 1179 C ALA A 148 3.774 6.551 42.806 1.00 42.24 C +ANISOU 1179 C ALA A 148 7926 4544 3578 -707 350 180 C +ATOM 1180 O ALA A 148 2.677 6.220 43.265 1.00 43.42 O +ANISOU 1180 O ALA A 148 8099 4691 3707 -860 470 158 O +ATOM 1181 CB ALA A 148 4.178 8.877 41.976 1.00 40.72 C +ANISOU 1181 CB ALA A 148 7469 4509 3493 -507 413 85 C +ATOM 1182 N ILE A 149 4.511 5.750 42.045 1.00 41.44 N +ANISOU 1182 N ILE A 149 7843 4377 3524 -598 195 218 N +ATOM 1183 CA ILE A 149 4.083 4.394 41.701 1.00 42.54 C +ANISOU 1183 CA ILE A 149 8049 4424 3688 -647 141 240 C +ATOM 1184 C ILE A 149 4.095 3.448 42.919 1.00 44.99 C +ANISOU 1184 C ILE A 149 8594 4628 3871 -809 109 325 C +ATOM 1185 O ILE A 149 3.202 2.636 43.064 1.00 45.52 O +ANISOU 1185 O ILE A 149 8721 4647 3927 -944 157 330 O +ATOM 1186 CB ILE A 149 4.976 3.793 40.584 1.00 41.61 C +ANISOU 1186 CB ILE A 149 7903 4251 3653 -477 -11 245 C +ATOM 1187 CG1 ILE A 149 4.850 4.589 39.280 1.00 39.99 C +ANISOU 1187 CG1 ILE A 149 7499 4141 3553 -346 21 166 C +ATOM 1188 CG2 ILE A 149 4.650 2.328 40.348 1.00 42.74 C +ANISOU 1188 CG2 ILE A 149 8151 4274 3813 -530 -82 271 C +ATOM 1189 CD1 ILE A 149 3.535 4.396 38.575 1.00 40.20 C +ANISOU 1189 CD1 ILE A 149 7431 4193 3648 -404 89 108 C +ATOM 1190 N MET A 150 5.108 3.531 43.776 1.00 47.59 N +ANISOU 1190 N MET A 150 9063 4913 4103 -805 15 396 N +ATOM 1191 CA MET A 150 5.147 2.738 45.006 1.00 51.75 C +ANISOU 1191 CA MET A 150 9844 5333 4484 -973 -31 489 C +ATOM 1192 C MET A 150 3.939 3.054 45.908 1.00 51.48 C +ANISOU 1192 C MET A 150 9864 5352 4342 -1195 178 461 C +ATOM 1193 O MET A 150 3.252 2.153 46.376 1.00 51.18 O +ANISOU 1193 O MET A 150 9964 5242 4239 -1365 217 496 O +ATOM 1194 CB MET A 150 6.427 3.015 45.787 1.00 56.30 C +ANISOU 1194 CB MET A 150 10545 5869 4977 -931 -177 565 C +ATOM 1195 CG MET A 150 7.695 2.293 45.326 1.00 60.32 C +ANISOU 1195 CG MET A 150 11075 6269 5572 -765 -412 623 C +ATOM 1196 SD MET A 150 9.085 2.619 46.490 1.00 69.86 S +ANISOU 1196 SD MET A 150 12441 7422 6681 -758 -600 722 S +ATOM 1197 CE MET A 150 10.029 1.079 46.352 1.00 71.30 C +ANISOU 1197 CE MET A 150 12746 7396 6945 -666 -877 818 C +ATOM 1198 N GLU A 151 3.689 4.342 46.134 1.00 50.25 N +ANISOU 1198 N GLU A 151 9598 5318 4177 -1193 323 389 N +ATOM 1199 CA GLU A 151 2.581 4.805 46.978 1.00 51.24 C +ANISOU 1199 CA GLU A 151 9744 5503 4219 -1386 553 333 C +ATOM 1200 C GLU A 151 1.212 4.395 46.432 1.00 49.75 C +ANISOU 1200 C GLU A 151 9420 5340 4140 -1464 695 264 C +ATOM 1201 O GLU A 151 0.359 3.944 47.187 1.00 51.84 O +ANISOU 1201 O GLU A 151 9787 5585 4322 -1674 832 263 O +ATOM 1202 CB GLU A 151 2.636 6.333 47.174 1.00 52.46 C +ANISOU 1202 CB GLU A 151 9780 5773 4379 -1332 671 252 C +ATOM 1203 CG GLU A 151 3.726 6.801 48.160 1.00 54.50 C +ANISOU 1203 CG GLU A 151 10220 6008 4478 -1349 582 313 C +ATOM 1204 CD GLU A 151 4.146 8.290 48.033 1.00 55.36 C +ANISOU 1204 CD GLU A 151 10193 6212 4628 -1231 625 243 C +ATOM 1205 OE1 GLU A 151 5.020 8.743 48.829 1.00 55.80 O +ANISOU 1205 OE1 GLU A 151 10389 6253 4558 -1251 550 286 O +ATOM 1206 OE2 GLU A 151 3.636 9.026 47.138 1.00 56.57 O +ANISOU 1206 OE2 GLU A 151 10108 6447 4938 -1121 716 152 O +ATOM 1207 N ALA A 152 1.008 4.561 45.130 1.00 46.51 N +ANISOU 1207 N ALA A 152 8785 4975 3911 -1307 662 207 N +ATOM 1208 CA ALA A 152 -0.260 4.202 44.480 1.00 45.45 C +ANISOU 1208 CA ALA A 152 8498 4864 3905 -1364 760 140 C +ATOM 1209 C ALA A 152 -0.515 2.686 44.461 1.00 45.29 C +ANISOU 1209 C ALA A 152 8620 4727 3859 -1477 684 206 C +ATOM 1210 O ALA A 152 -1.660 2.242 44.533 1.00 46.03 O +ANISOU 1210 O ALA A 152 8673 4823 3993 -1630 805 170 O +ATOM 1211 CB ALA A 152 -0.293 4.758 43.059 1.00 43.67 C +ANISOU 1211 CB ALA A 152 8031 4702 3858 -1166 702 76 C +ATOM 1212 N ALA A 153 0.552 1.908 44.351 1.00 44.09 N +ANISOU 1212 N ALA A 153 8626 4468 3657 -1399 483 297 N +ATOM 1213 CA ALA A 153 0.459 0.461 44.410 1.00 45.29 C +ANISOU 1213 CA ALA A 153 8948 4481 3777 -1497 387 369 C +ATOM 1214 C ALA A 153 -0.020 -0.033 45.782 1.00 47.78 C +ANISOU 1214 C ALA A 153 9490 4739 3923 -1759 485 429 C +ATOM 1215 O ALA A 153 -0.883 -0.901 45.859 1.00 49.34 O +ANISOU 1215 O ALA A 153 9742 4881 4123 -1924 542 437 O +ATOM 1216 CB ALA A 153 1.800 -0.161 44.066 1.00 44.50 C +ANISOU 1216 CB ALA A 153 8961 4269 3677 -1337 148 445 C +ATOM 1217 N VAL A 154 0.543 0.498 46.862 1.00 48.42 N +ANISOU 1217 N VAL A 154 9720 4829 3849 -1813 503 473 N +ATOM 1218 CA VAL A 154 0.050 0.163 48.193 1.00 50.89 C +ANISOU 1218 CA VAL A 154 10265 5100 3971 -2082 622 522 C +ATOM 1219 C VAL A 154 -1.415 0.569 48.340 1.00 51.90 C +ANISOU 1219 C VAL A 154 10243 5335 4143 -2247 911 411 C +ATOM 1220 O VAL A 154 -2.239 -0.241 48.737 1.00 53.48 O +ANISOU 1220 O VAL A 154 10541 5483 4294 -2462 1007 428 O +ATOM 1221 CB VAL A 154 0.887 0.822 49.331 1.00 51.47 C +ANISOU 1221 CB VAL A 154 10525 5175 3854 -2118 598 575 C +ATOM 1222 CG1 VAL A 154 0.216 0.624 50.679 1.00 53.47 C +ANISOU 1222 CG1 VAL A 154 11015 5407 3892 -2421 770 602 C +ATOM 1223 CG2 VAL A 154 2.304 0.260 49.373 1.00 51.11 C +ANISOU 1223 CG2 VAL A 154 10650 5001 3768 -1991 297 700 C +ATOM 1224 N GLN A 155 -1.725 1.814 48.012 1.00 51.27 N +ANISOU 1224 N GLN A 155 9918 5395 4167 -2146 1045 295 N +ATOM 1225 CA GLN A 155 -3.052 2.409 48.235 1.00 53.14 C +ANISOU 1225 CA GLN A 155 9981 5739 4470 -2278 1328 171 C +ATOM 1226 C GLN A 155 -4.185 1.788 47.423 1.00 53.59 C +ANISOU 1226 C GLN A 155 9850 5801 4708 -2327 1384 116 C +ATOM 1227 O GLN A 155 -5.339 1.801 47.858 1.00 55.52 O +ANISOU 1227 O GLN A 155 10021 6091 4982 -2516 1614 42 O +ATOM 1228 CB GLN A 155 -2.955 3.892 47.870 1.00 52.69 C +ANISOU 1228 CB GLN A 155 9692 5806 4521 -2100 1395 67 C +ATOM 1229 CG GLN A 155 -4.242 4.691 47.691 1.00 54.48 C +ANISOU 1229 CG GLN A 155 9641 6144 4913 -2136 1639 -83 C +ATOM 1230 CD GLN A 155 -3.979 6.164 47.319 1.00 54.28 C +ANISOU 1230 CD GLN A 155 9421 6212 4989 -1940 1662 -168 C +ATOM 1231 OE1 GLN A 155 -4.816 7.040 47.577 1.00 56.98 O +ANISOU 1231 OE1 GLN A 155 9596 6633 5419 -1977 1876 -291 O +ATOM 1232 NE2 GLN A 155 -2.814 6.444 46.730 1.00 52.81 N +ANISOU 1232 NE2 GLN A 155 9253 6011 4798 -1735 1447 -108 N +ATOM 1233 N ASN A 156 -3.857 1.295 46.222 1.00 51.94 N +ANISOU 1233 N ASN A 156 9552 5550 4630 -2157 1181 140 N +ATOM 1234 CA ASN A 156 -4.852 0.711 45.306 1.00 51.92 C +ANISOU 1234 CA ASN A 156 9372 5547 4807 -2185 1190 89 C +ATOM 1235 C ASN A 156 -4.816 -0.812 45.254 1.00 53.14 C +ANISOU 1235 C ASN A 156 9726 5557 4908 -2297 1064 183 C +ATOM 1236 O ASN A 156 -5.644 -1.419 44.582 1.00 54.34 O +ANISOU 1236 O ASN A 156 9764 5692 5190 -2352 1065 148 O +ATOM 1237 CB ASN A 156 -4.669 1.268 43.906 1.00 49.67 C +ANISOU 1237 CB ASN A 156 8845 5318 4706 -1933 1065 33 C +ATOM 1238 CG ASN A 156 -5.107 2.707 43.775 1.00 49.08 C +ANISOU 1238 CG ASN A 156 8523 5379 4744 -1847 1202 -75 C +ATOM 1239 OD1 ASN A 156 -6.089 3.102 44.385 1.00 50.83 O +ANISOU 1239 OD1 ASN A 156 8646 5661 5005 -1990 1419 -152 O +ATOM 1240 ND2 ASN A 156 -4.408 3.486 42.933 1.00 47.20 N +ANISOU 1240 ND2 ASN A 156 8177 5182 4572 -1614 1078 -89 N +ATOM 1241 N ASN A 157 -3.869 -1.422 45.972 1.00 53.53 N +ANISOU 1241 N ASN A 157 10073 5491 4772 -2334 944 303 N +ATOM 1242 CA ASN A 157 -3.676 -2.874 46.008 1.00 54.46 C +ANISOU 1242 CA ASN A 157 10419 5440 4830 -2427 796 407 C +ATOM 1243 C ASN A 157 -3.242 -3.459 44.661 1.00 53.04 C +ANISOU 1243 C ASN A 157 10162 5194 4795 -2226 580 406 C +ATOM 1244 O ASN A 157 -3.710 -4.531 44.256 1.00 54.15 O +ANISOU 1244 O ASN A 157 10351 5237 4985 -2311 522 423 O +ATOM 1245 CB ASN A 157 -4.938 -3.577 46.532 1.00 57.21 C +ANISOU 1245 CB ASN A 157 10815 5763 5157 -2724 971 398 C +ATOM 1246 CG ASN A 157 -4.927 -3.784 48.040 1.00 59.20 C +ANISOU 1246 CG ASN A 157 11357 5966 5169 -2973 1085 476 C +ATOM 1247 OD1 ASN A 157 -4.158 -3.160 48.771 1.00 59.07 O +ANISOU 1247 OD1 ASN A 157 11466 5967 5007 -2936 1074 513 O +ATOM 1248 ND2 ASN A 157 -5.798 -4.663 48.509 1.00 61.49 N +ANISOU 1248 ND2 ASN A 157 11763 6191 5408 -3245 1195 502 N +ATOM 1249 N TRP A 158 -2.318 -2.766 44.000 1.00 50.52 N +ANISOU 1249 N TRP A 158 9739 4922 4531 -1971 466 385 N +ATOM 1250 CA TRP A 158 -1.810 -3.186 42.705 1.00 49.00 C +ANISOU 1250 CA TRP A 158 9475 4680 4461 -1770 285 368 C +ATOM 1251 C TRP A 158 -0.695 -4.198 42.883 1.00 49.69 C +ANISOU 1251 C TRP A 158 9809 4592 4477 -1712 76 472 C +ATOM 1252 O TRP A 158 0.060 -4.102 43.851 1.00 50.34 O +ANISOU 1252 O TRP A 158 10063 4631 4431 -1731 33 554 O +ATOM 1253 CB TRP A 158 -1.198 -2.001 41.964 1.00 46.61 C +ANISOU 1253 CB TRP A 158 8976 4496 4235 -1532 261 304 C +ATOM 1254 CG TRP A 158 -2.138 -0.918 41.514 1.00 45.54 C +ANISOU 1254 CG TRP A 158 8573 4520 4210 -1521 414 197 C +ATOM 1255 CD1 TRP A 158 -3.505 -0.966 41.461 1.00 46.47 C +ANISOU 1255 CD1 TRP A 158 8559 4685 4412 -1673 551 135 C +ATOM 1256 CD2 TRP A 158 -1.757 0.345 40.984 1.00 43.28 C +ANISOU 1256 CD2 TRP A 158 8109 4350 3984 -1340 423 140 C +ATOM 1257 NE1 TRP A 158 -3.999 0.212 40.950 1.00 45.23 N +ANISOU 1257 NE1 TRP A 158 8147 4663 4374 -1585 635 42 N +ATOM 1258 CE2 TRP A 158 -2.945 1.032 40.646 1.00 43.53 C +ANISOU 1258 CE2 TRP A 158 7913 4488 4137 -1384 557 48 C +ATOM 1259 CE3 TRP A 158 -0.523 0.961 40.754 1.00 41.71 C +ANISOU 1259 CE3 TRP A 158 7919 4171 3759 -1149 328 159 C +ATOM 1260 CZ2 TRP A 158 -2.937 2.312 40.097 1.00 42.50 C +ANISOU 1260 CZ2 TRP A 158 7584 4471 4094 -1240 586 -17 C +ATOM 1261 CZ3 TRP A 158 -0.505 2.232 40.226 1.00 40.70 C +ANISOU 1261 CZ3 TRP A 158 7598 4162 3701 -1022 373 93 C +ATOM 1262 CH2 TRP A 158 -1.713 2.903 39.897 1.00 41.07 C +ANISOU 1262 CH2 TRP A 158 7438 4303 3862 -1065 496 9 C +ATOM 1263 N GLN A 159 -0.565 -5.110 41.920 1.00 49.81 N +ANISOU 1263 N GLN A 159 9835 4504 4584 -1630 -60 463 N +ATOM 1264 CA GLN A 159 0.590 -6.003 41.815 1.00 50.16 C +ANISOU 1264 CA GLN A 159 10061 4378 4619 -1510 -273 533 C +ATOM 1265 C GLN A 159 1.577 -5.437 40.792 1.00 47.63 C +ANISOU 1265 C GLN A 159 9591 4110 4395 -1231 -362 472 C +ATOM 1266 O GLN A 159 1.505 -5.708 39.594 1.00 47.76 O +ANISOU 1266 O GLN A 159 9509 4118 4520 -1123 -406 398 O +ATOM 1267 CB GLN A 159 0.176 -7.410 41.393 1.00 52.02 C +ANISOU 1267 CB GLN A 159 10419 4448 4898 -1592 -364 549 C +ATOM 1268 CG GLN A 159 -0.665 -8.166 42.398 1.00 55.07 C +ANISOU 1268 CG GLN A 159 10995 4747 5182 -1880 -299 625 C +ATOM 1269 CD GLN A 159 -0.923 -9.606 41.975 1.00 57.29 C +ANISOU 1269 CD GLN A 159 11421 4835 5508 -1950 -418 650 C +ATOM 1270 OE1 GLN A 159 -0.791 -9.961 40.800 1.00 57.84 O +ANISOU 1270 OE1 GLN A 159 11405 4868 5700 -1806 -507 579 O +ATOM 1271 NE2 GLN A 159 -1.277 -10.451 42.935 1.00 60.20 N +ANISOU 1271 NE2 GLN A 159 12032 5071 5768 -2182 -421 751 N +ATOM 1272 N VAL A 160 2.512 -4.659 41.284 1.00 46.07 N +ANISOU 1272 N VAL A 160 9390 3962 4151 -1129 -385 502 N +ATOM 1273 CA VAL A 160 3.564 -4.103 40.480 1.00 44.48 C +ANISOU 1273 CA VAL A 160 9063 3806 4030 -884 -460 455 C +ATOM 1274 C VAL A 160 4.839 -4.910 40.665 1.00 45.22 C +ANISOU 1274 C VAL A 160 9310 3733 4139 -767 -657 522 C +ATOM 1275 O VAL A 160 5.300 -5.094 41.761 1.00 46.27 O +ANISOU 1275 O VAL A 160 9606 3789 4184 -832 -730 620 O +ATOM 1276 CB VAL A 160 3.821 -2.637 40.887 1.00 43.11 C +ANISOU 1276 CB VAL A 160 8767 3797 3816 -842 -362 439 C +ATOM 1277 CG1 VAL A 160 4.853 -2.018 39.967 1.00 41.67 C +ANISOU 1277 CG1 VAL A 160 8440 3671 3721 -605 -421 385 C +ATOM 1278 CG2 VAL A 160 2.526 -1.839 40.841 1.00 42.69 C +ANISOU 1278 CG2 VAL A 160 8564 3891 3764 -960 -168 373 C +ATOM 1279 N THR A 161 5.410 -5.398 39.584 1.00 45.41 N +ANISOU 1279 N THR A 161 9281 3693 4279 -595 -747 463 N +ATOM 1280 CA THR A 161 6.699 -6.059 39.634 1.00 46.31 C +ANISOU 1280 CA THR A 161 9487 3654 4453 -444 -927 501 C +ATOM 1281 C THR A 161 7.738 -5.061 39.136 1.00 44.92 C +ANISOU 1281 C THR A 161 9132 3591 4344 -240 -921 445 C +ATOM 1282 O THR A 161 7.823 -4.788 37.943 1.00 43.54 O +ANISOU 1282 O THR A 161 8807 3485 4248 -118 -868 341 O +ATOM 1283 CB THR A 161 6.690 -7.302 38.733 1.00 47.65 C +ANISOU 1283 CB THR A 161 9717 3665 4722 -383 -1013 453 C +ATOM 1284 OG1 THR A 161 5.591 -8.151 39.117 1.00 49.26 O +ANISOU 1284 OG1 THR A 161 10072 3779 4865 -596 -999 498 O +ATOM 1285 CG2 THR A 161 8.024 -8.046 38.846 1.00 48.76 C +ANISOU 1285 CG2 THR A 161 9946 3624 4953 -219 -1204 485 C +ATOM 1286 N ALA A 162 8.510 -4.496 40.056 1.00 44.97 N +ANISOU 1286 N ALA A 162 9162 3616 4306 -221 -975 515 N +ATOM 1287 CA ALA A 162 9.464 -3.447 39.703 1.00 43.71 C +ANISOU 1287 CA ALA A 162 8828 3575 4204 -56 -960 469 C +ATOM 1288 C ALA A 162 10.849 -4.022 39.485 1.00 44.80 C +ANISOU 1288 C ALA A 162 8963 3584 4473 131 -1126 469 C +ATOM 1289 O ALA A 162 11.278 -4.879 40.245 1.00 46.16 O +ANISOU 1289 O ALA A 162 9298 3587 4652 113 -1291 558 O +ATOM 1290 CB ALA A 162 9.499 -2.396 40.791 1.00 42.88 C +ANISOU 1290 CB ALA A 162 8732 3575 3985 -147 -918 531 C +ATOM 1291 N ARG A 163 11.533 -3.557 38.443 1.00 44.76 N +ANISOU 1291 N ARG A 163 8775 3653 4577 306 -1083 369 N +ATOM 1292 CA ARG A 163 12.912 -3.943 38.165 1.00 46.61 C +ANISOU 1292 CA ARG A 163 8952 3789 4966 500 -1207 344 C +ATOM 1293 C ARG A 163 13.726 -2.739 37.737 1.00 45.90 C +ANISOU 1293 C ARG A 163 8656 3856 4926 618 -1133 285 C +ATOM 1294 O ARG A 163 13.335 -1.993 36.843 1.00 43.92 O +ANISOU 1294 O ARG A 163 8283 3752 4653 628 -977 202 O +ATOM 1295 CB ARG A 163 12.973 -4.982 37.047 1.00 48.12 C +ANISOU 1295 CB ARG A 163 9144 3866 5273 606 -1215 247 C +ATOM 1296 CG ARG A 163 12.447 -6.352 37.431 1.00 50.73 C +ANISOU 1296 CG ARG A 163 9685 3993 5595 520 -1328 303 C +ATOM 1297 CD ARG A 163 13.436 -7.154 38.282 1.00 53.44 C +ANISOU 1297 CD ARG A 163 10140 4133 6031 592 -1553 391 C +ATOM 1298 NE ARG A 163 12.947 -8.516 38.466 1.00 55.73 N +ANISOU 1298 NE ARG A 163 10639 4211 6324 521 -1660 434 N +ATOM 1299 CZ ARG A 163 12.019 -8.878 39.358 1.00 57.07 C +ANISOU 1299 CZ ARG A 163 11008 4328 6347 306 -1688 547 C +ATOM 1300 NH1 ARG A 163 11.465 -7.979 40.189 1.00 56.09 N +ANISOU 1300 NH1 ARG A 163 10903 4350 6058 143 -1607 621 N +ATOM 1301 NH2 ARG A 163 11.647 -10.164 39.424 1.00 58.83 N +ANISOU 1301 NH2 ARG A 163 11422 4343 6589 248 -1790 580 N +ATOM 1302 N SER A 164 14.868 -2.583 38.389 1.00 47.98 N +ANISOU 1302 N SER A 164 8890 4077 5262 699 -1262 335 N +ATOM 1303 CA SER A 164 15.758 -1.453 38.223 1.00 48.01 C +ANISOU 1303 CA SER A 164 8709 4212 5318 790 -1219 300 C +ATOM 1304 C SER A 164 16.797 -1.773 37.185 1.00 49.72 C +ANISOU 1304 C SER A 164 8772 4391 5726 988 -1217 190 C +ATOM 1305 O SER A 164 17.771 -2.461 37.483 1.00 51.59 O +ANISOU 1305 O SER A 164 9002 4486 6112 1099 -1376 206 O +ATOM 1306 CB SER A 164 16.473 -1.167 39.529 1.00 48.94 C +ANISOU 1306 CB SER A 164 8878 4293 5422 762 -1381 413 C +ATOM 1307 OG SER A 164 17.504 -0.231 39.327 1.00 49.76 O +ANISOU 1307 OG SER A 164 8792 4497 5616 866 -1367 374 O +ATOM 1308 N VAL A 165 16.633 -1.214 35.995 1.00 49.19 N +ANISOU 1308 N VAL A 165 8577 4452 5660 1031 -1038 78 N +ATOM 1309 CA VAL A 165 17.439 -1.595 34.853 1.00 51.20 C +ANISOU 1309 CA VAL A 165 8708 4674 6069 1195 -987 -49 C +ATOM 1310 C VAL A 165 18.532 -0.575 34.500 1.00 51.83 C +ANISOU 1310 C VAL A 165 8579 4877 6236 1291 -916 -103 C +ATOM 1311 O VAL A 165 19.179 -0.674 33.449 1.00 51.47 O +ANISOU 1311 O VAL A 165 8413 4843 6301 1409 -820 -226 O +ATOM 1312 CB VAL A 165 16.519 -1.839 33.630 1.00 51.60 C +ANISOU 1312 CB VAL A 165 8793 4762 6050 1166 -838 -147 C +ATOM 1313 CG1 VAL A 165 15.511 -2.928 33.962 1.00 52.58 C +ANISOU 1313 CG1 VAL A 165 9111 4752 6113 1069 -915 -99 C +ATOM 1314 CG2 VAL A 165 15.777 -0.573 33.198 1.00 49.57 C +ANISOU 1314 CG2 VAL A 165 8480 4705 5649 1070 -683 -157 C +ATOM 1315 N GLY A 166 18.739 0.407 35.374 1.00 52.49 N +ANISOU 1315 N GLY A 166 8627 5051 6266 1228 -954 -18 N +ATOM 1316 CA GLY A 166 19.651 1.504 35.069 1.00 53.21 C +ANISOU 1316 CA GLY A 166 8527 5271 6419 1286 -878 -61 C +ATOM 1317 C GLY A 166 21.100 1.126 34.861 1.00 55.70 C +ANISOU 1317 C GLY A 166 8681 5513 6966 1452 -942 -123 C +ATOM 1318 O GLY A 166 21.802 1.792 34.126 1.00 55.79 O +ANISOU 1318 O GLY A 166 8520 5625 7050 1513 -818 -209 O +ATOM 1319 N ASN A 167 21.552 0.063 35.505 1.00 59.64 N +ANISOU 1319 N ASN A 167 9234 5833 7592 1520 -1135 -82 N +ATOM 1320 CA ASN A 167 22.966 -0.311 35.494 1.00 63.52 C +ANISOU 1320 CA ASN A 167 9554 6234 8343 1686 -1234 -131 C +ATOM 1321 C ASN A 167 23.309 -1.413 34.483 1.00 66.09 C +ANISOU 1321 C ASN A 167 9831 6439 8838 1835 -1178 -270 C +ATOM 1322 O ASN A 167 24.487 -1.707 34.255 1.00 67.82 O +ANISOU 1322 O ASN A 167 9871 6593 9302 1991 -1212 -349 O +ATOM 1323 CB ASN A 167 23.381 -0.727 36.905 1.00 65.31 C +ANISOU 1323 CB ASN A 167 9861 6322 8628 1680 -1519 7 C +ATOM 1324 CG ASN A 167 23.113 0.368 37.932 1.00 65.05 C +ANISOU 1324 CG ASN A 167 9889 6404 8422 1527 -1569 131 C +ATOM 1325 OD1 ASN A 167 23.230 1.571 37.636 1.00 63.62 O +ANISOU 1325 OD1 ASN A 167 9587 6397 8185 1488 -1427 99 O +ATOM 1326 ND2 ASN A 167 22.726 -0.041 39.141 1.00 65.96 N +ANISOU 1326 ND2 ASN A 167 10210 6413 8437 1430 -1765 270 N +ATOM 1327 N ILE A 168 22.297 -2.005 33.859 1.00 66.45 N +ANISOU 1327 N ILE A 168 10027 6454 8766 1788 -1087 -311 N +ATOM 1328 CA ILE A 168 22.522 -3.104 32.933 1.00 68.11 C +ANISOU 1328 CA ILE A 168 10230 6534 9114 1915 -1036 -446 C +ATOM 1329 C ILE A 168 23.332 -2.611 31.725 1.00 70.77 C +ANISOU 1329 C ILE A 168 10355 6979 9555 2015 -817 -616 C +ATOM 1330 O ILE A 168 22.926 -1.678 31.024 1.00 71.07 O +ANISOU 1330 O ILE A 168 10369 7196 9437 1931 -626 -654 O +ATOM 1331 CB ILE A 168 21.193 -3.717 32.455 1.00 66.08 C +ANISOU 1331 CB ILE A 168 10183 6240 8681 1817 -974 -457 C +ATOM 1332 CG1 ILE A 168 20.423 -4.312 33.635 1.00 65.46 C +ANISOU 1332 CG1 ILE A 168 10317 6040 8512 1708 -1174 -298 C +ATOM 1333 CG2 ILE A 168 21.436 -4.789 31.398 1.00 67.49 C +ANISOU 1333 CG2 ILE A 168 10364 6289 8989 1942 -903 -617 C +ATOM 1334 CD1 ILE A 168 19.008 -4.757 33.284 1.00 64.52 C +ANISOU 1334 CD1 ILE A 168 10391 5911 8211 1575 -1110 -293 C +ATOM 1335 N LYS A 169 24.494 -3.214 31.513 1.00 75.12 N +ANISOU 1335 N LYS A 169 10749 7417 10374 2190 -848 -716 N +ATOM 1336 CA LYS A 169 25.294 -2.945 30.320 1.00 77.56 C +ANISOU 1336 CA LYS A 169 10862 7804 10800 2287 -617 -901 C +ATOM 1337 C LYS A 169 25.219 -4.130 29.326 1.00 80.48 C +ANISOU 1337 C LYS A 169 11295 8035 11248 2387 -521 -1065 C +ATOM 1338 O LYS A 169 25.641 -3.992 28.180 1.00 81.54 O +ANISOU 1338 O LYS A 169 11327 8234 11419 2436 -289 -1236 O +ATOM 1339 CB LYS A 169 26.746 -2.637 30.715 1.00 79.03 C +ANISOU 1339 CB LYS A 169 10779 7986 11260 2412 -680 -926 C +ATOM 1340 N ASP A 170 24.654 -5.266 29.762 1.00 81.48 N +ANISOU 1340 N ASP A 170 11608 7968 11383 2399 -693 -1013 N +ATOM 1341 CA ASP A 170 24.529 -6.479 28.928 1.00 82.47 C +ANISOU 1341 CA ASP A 170 11822 7928 11583 2489 -633 -1160 C +ATOM 1342 C ASP A 170 23.084 -6.649 28.415 1.00 80.06 C +ANISOU 1342 C ASP A 170 11766 7657 10995 2331 -560 -1145 C +ATOM 1343 O ASP A 170 22.182 -6.993 29.177 1.00 79.45 O +ANISOU 1343 O ASP A 170 11873 7512 10800 2226 -723 -1001 O +ATOM 1344 CB ASP A 170 24.966 -7.712 29.753 1.00 85.48 C +ANISOU 1344 CB ASP A 170 12240 8038 12200 2620 -897 -1117 C +ATOM 1345 CG ASP A 170 25.038 -9.016 28.932 1.00 88.29 C +ANISOU 1345 CG ASP A 170 12663 8190 12691 2745 -847 -1288 C +ATOM 1346 OD1 ASP A 170 24.721 -9.027 27.721 1.00 89.60 O +ANISOU 1346 OD1 ASP A 170 12866 8424 12753 2723 -607 -1445 O +ATOM 1347 OD2 ASP A 170 25.432 -10.060 29.509 1.00 88.66 O +ANISOU 1347 OD2 ASP A 170 12740 7993 12951 2868 -1061 -1266 O +ATOM 1348 N VAL A 171 22.872 -6.406 27.127 1.00 79.08 N +ANISOU 1348 N VAL A 171 11648 7636 10762 2304 -318 -1293 N +ATOM 1349 CA VAL A 171 21.551 -6.577 26.495 1.00 78.11 C +ANISOU 1349 CA VAL A 171 11745 7542 10389 2160 -254 -1297 C +ATOM 1350 C VAL A 171 20.930 -7.974 26.657 1.00 77.61 C +ANISOU 1350 C VAL A 171 11884 7251 10352 2168 -395 -1295 C +ATOM 1351 O VAL A 171 19.719 -8.131 26.611 1.00 77.75 O +ANISOU 1351 O VAL A 171 12087 7276 10177 2023 -427 -1231 O +ATOM 1352 CB VAL A 171 21.582 -6.261 24.975 1.00 79.48 C +ANISOU 1352 CB VAL A 171 11911 7826 10461 2147 15 -1480 C +ATOM 1353 CG1 VAL A 171 21.970 -4.795 24.735 1.00 78.10 C +ANISOU 1353 CG1 VAL A 171 11582 7886 10204 2092 163 -1465 C +ATOM 1354 CG2 VAL A 171 22.491 -7.247 24.223 1.00 81.85 C +ANISOU 1354 CG2 VAL A 171 12157 7972 10970 2319 114 -1692 C +ATOM 1355 N GLN A 172 21.750 -8.990 26.836 1.00 78.21 N +ANISOU 1355 N GLN A 172 11920 7117 10679 2336 -485 -1365 N +ATOM 1356 CA GLN A 172 21.238 -10.320 27.161 1.00 79.49 C +ANISOU 1356 CA GLN A 172 12279 7037 10887 2345 -655 -1340 C +ATOM 1357 C GLN A 172 20.439 -10.322 28.476 1.00 77.32 C +ANISOU 1357 C GLN A 172 12141 6730 10504 2208 -882 -1104 C +ATOM 1358 O GLN A 172 19.518 -11.105 28.647 1.00 77.59 O +ANISOU 1358 O GLN A 172 12386 6643 10451 2114 -977 -1051 O +ATOM 1359 CB GLN A 172 22.400 -11.334 27.212 1.00 82.92 C +ANISOU 1359 CB GLN A 172 12619 7235 11649 2573 -733 -1452 C +ATOM 1360 CG GLN A 172 21.997 -12.803 27.373 1.00 85.19 C +ANISOU 1360 CG GLN A 172 13116 7238 12014 2608 -895 -1458 C +ATOM 1361 CD GLN A 172 21.427 -13.457 26.108 1.00 86.08 C +ANISOU 1361 CD GLN A 172 13378 7296 12032 2583 -729 -1639 C +ATOM 1362 OE1 GLN A 172 21.223 -12.800 25.086 1.00 85.82 O +ANISOU 1362 OE1 GLN A 172 13317 7448 11842 2521 -496 -1751 O +ATOM 1363 NE2 GLN A 172 21.161 -14.753 26.185 1.00 86.43 N +ANISOU 1363 NE2 GLN A 172 13598 7077 12162 2622 -862 -1664 N +ATOM 1364 N GLU A 173 20.788 -9.441 29.403 1.00 76.11 N +ANISOU 1364 N GLU A 173 11877 6689 10353 2183 -959 -968 N +ATOM 1365 CA GLU A 173 20.147 -9.407 30.722 1.00 74.95 C +ANISOU 1365 CA GLU A 173 11862 6513 10102 2050 -1162 -752 C +ATOM 1366 C GLU A 173 18.722 -8.826 30.707 1.00 70.64 C +ANISOU 1366 C GLU A 173 11449 6123 9267 1826 -1086 -669 C +ATOM 1367 O GLU A 173 17.934 -9.096 31.622 1.00 69.11 O +ANISOU 1367 O GLU A 173 11416 5872 8970 1693 -1221 -521 O +ATOM 1368 CB GLU A 173 21.026 -8.633 31.698 1.00 77.05 C +ANISOU 1368 CB GLU A 173 11973 6844 10459 2093 -1269 -647 C +ATOM 1369 CG GLU A 173 20.731 -8.904 33.169 1.00 78.80 C +ANISOU 1369 CG GLU A 173 12343 6958 10637 2002 -1524 -439 C +ATOM 1370 CD GLU A 173 21.741 -8.239 34.091 1.00 80.55 C +ANISOU 1370 CD GLU A 173 12416 7216 10970 2060 -1656 -350 C +ATOM 1371 OE1 GLU A 173 21.327 -7.555 35.060 1.00 79.45 O +ANISOU 1371 OE1 GLU A 173 12347 7169 10670 1914 -1730 -194 O +ATOM 1372 OE2 GLU A 173 22.958 -8.398 33.834 1.00 83.92 O +ANISOU 1372 OE2 GLU A 173 12650 7579 11654 2251 -1682 -444 O +ATOM 1373 N PHE A 174 18.395 -8.030 29.685 1.00 67.80 N +ANISOU 1373 N PHE A 174 11023 5954 8782 1781 -873 -764 N +ATOM 1374 CA PHE A 174 17.007 -7.590 29.468 1.00 64.94 C +ANISOU 1374 CA PHE A 174 10775 5718 8180 1589 -804 -714 C +ATOM 1375 C PHE A 174 16.125 -8.779 29.094 1.00 65.58 C +ANISOU 1375 C PHE A 174 11055 5640 8221 1528 -847 -749 C +ATOM 1376 O PHE A 174 14.955 -8.844 29.484 1.00 63.89 O +ANISOU 1376 O PHE A 174 10970 5440 7864 1360 -893 -652 O +ATOM 1377 CB PHE A 174 16.900 -6.535 28.361 1.00 62.52 C +ANISOU 1377 CB PHE A 174 10369 5625 7761 1563 -592 -810 C +ATOM 1378 CG PHE A 174 17.402 -5.174 28.751 1.00 60.86 C +ANISOU 1378 CG PHE A 174 9994 5600 7529 1559 -541 -749 C +ATOM 1379 CD1 PHE A 174 16.787 -4.453 29.770 1.00 59.20 C +ANISOU 1379 CD1 PHE A 174 9803 5479 7209 1433 -612 -592 C +ATOM 1380 CD2 PHE A 174 18.474 -4.588 28.082 1.00 61.05 C +ANISOU 1380 CD2 PHE A 174 9845 5710 7640 1670 -408 -857 C +ATOM 1381 CE1 PHE A 174 17.242 -3.192 30.123 1.00 57.43 C +ANISOU 1381 CE1 PHE A 174 9440 5415 6965 1426 -568 -543 C +ATOM 1382 CE2 PHE A 174 18.936 -3.321 28.440 1.00 59.30 C +ANISOU 1382 CE2 PHE A 174 9477 5653 7400 1655 -365 -799 C +ATOM 1383 CZ PHE A 174 18.311 -2.623 29.454 1.00 57.64 C +ANISOU 1383 CZ PHE A 174 9299 5521 7080 1535 -452 -642 C +ATOM 1384 N ARG A 175 16.690 -9.711 28.330 1.00 67.58 N +ANISOU 1384 N ARG A 175 11327 5740 8607 1661 -824 -897 N +ATOM 1385 CA ARG A 175 15.956 -10.904 27.935 1.00 69.49 C +ANISOU 1385 CA ARG A 175 11765 5808 8828 1614 -872 -945 C +ATOM 1386 C ARG A 175 15.605 -11.751 29.140 1.00 69.36 C +ANISOU 1386 C ARG A 175 11897 5605 8850 1554 -1090 -794 C +ATOM 1387 O ARG A 175 14.490 -12.243 29.250 1.00 67.22 O +ANISOU 1387 O ARG A 175 11795 5282 8464 1398 -1137 -739 O +ATOM 1388 CB ARG A 175 16.757 -11.760 26.958 1.00 73.58 C +ANISOU 1388 CB ARG A 175 12276 6176 9503 1785 -805 -1145 C +ATOM 1389 CG ARG A 175 17.006 -11.105 25.626 1.00 75.18 C +ANISOU 1389 CG ARG A 175 12388 6539 9637 1816 -572 -1314 C +ATOM 1390 CD ARG A 175 17.744 -12.067 24.727 1.00 79.14 C +ANISOU 1390 CD ARG A 175 12906 6871 10291 1975 -495 -1523 C +ATOM 1391 NE ARG A 175 18.106 -11.372 23.501 1.00 80.82 N +ANISOU 1391 NE ARG A 175 13032 7245 10427 1996 -254 -1685 N +ATOM 1392 CZ ARG A 175 18.645 -11.938 22.429 1.00 83.58 C +ANISOU 1392 CZ ARG A 175 13401 7512 10843 2098 -106 -1902 C +ATOM 1393 NH1 ARG A 175 18.916 -13.243 22.393 1.00 86.01 N +ANISOU 1393 NH1 ARG A 175 13796 7563 11318 2210 -177 -1999 N +ATOM 1394 NH2 ARG A 175 18.916 -11.180 21.373 1.00 84.91 N +ANISOU 1394 NH2 ARG A 175 13509 7850 10902 2082 120 -2027 N +ATOM 1395 N ARG A 176 16.562 -11.927 30.043 1.00 71.20 N +ANISOU 1395 N ARG A 176 12072 5733 9246 1669 -1229 -724 N +ATOM 1396 CA ARG A 176 16.325 -12.752 31.214 1.00 73.41 C +ANISOU 1396 CA ARG A 176 12518 5817 9555 1610 -1454 -571 C +ATOM 1397 C ARG A 176 15.202 -12.151 32.069 1.00 69.66 C +ANISOU 1397 C ARG A 176 12134 5473 8861 1375 -1473 -399 C +ATOM 1398 O ARG A 176 14.375 -12.887 32.616 1.00 68.96 O +ANISOU 1398 O ARG A 176 12241 5257 8700 1235 -1577 -304 O +ATOM 1399 CB ARG A 176 17.612 -12.958 32.016 1.00 78.06 C +ANISOU 1399 CB ARG A 176 13022 6273 10361 1779 -1623 -522 C +ATOM 1400 CG ARG A 176 17.609 -14.220 32.884 1.00 83.09 C +ANISOU 1400 CG ARG A 176 13861 6615 11092 1779 -1876 -415 C +ATOM 1401 CD ARG A 176 18.997 -14.879 33.001 1.00 89.15 C +ANISOU 1401 CD ARG A 176 14534 7169 12167 2029 -2024 -473 C +ATOM 1402 NE ARG A 176 20.062 -13.915 33.344 1.00 92.43 N +ANISOU 1402 NE ARG A 176 14708 7719 12689 2141 -2027 -459 N +ATOM 1403 CZ ARG A 176 21.098 -13.574 32.563 1.00 94.97 C +ANISOU 1403 CZ ARG A 176 14783 8102 13198 2333 -1899 -626 C +ATOM 1404 NH1 ARG A 176 21.271 -14.114 31.355 1.00 97.47 N +ANISOU 1404 NH1 ARG A 176 15061 8358 13613 2448 -1743 -835 N +ATOM 1405 NH2 ARG A 176 21.980 -12.678 32.997 1.00 94.73 N +ANISOU 1405 NH2 ARG A 176 14544 8195 13253 2401 -1920 -591 N +ATOM 1406 N ILE A 177 15.146 -10.818 32.138 1.00 65.89 N +ANISOU 1406 N ILE A 177 11513 5243 8279 1327 -1359 -370 N +ATOM 1407 CA ILE A 177 14.081 -10.124 32.874 1.00 63.03 C +ANISOU 1407 CA ILE A 177 11206 5021 7718 1115 -1341 -235 C +ATOM 1408 C ILE A 177 12.708 -10.304 32.220 1.00 60.92 C +ANISOU 1408 C ILE A 177 11032 4802 7310 955 -1244 -272 C +ATOM 1409 O ILE A 177 11.729 -10.578 32.898 1.00 60.07 O +ANISOU 1409 O ILE A 177 11058 4664 7100 777 -1293 -167 O +ATOM 1410 CB ILE A 177 14.389 -8.621 33.023 1.00 61.58 C +ANISOU 1410 CB ILE A 177 10840 5080 7475 1117 -1237 -213 C +ATOM 1411 CG1 ILE A 177 15.566 -8.421 33.971 1.00 62.41 C +ANISOU 1411 CG1 ILE A 177 10878 5138 7696 1221 -1371 -136 C +ATOM 1412 CG2 ILE A 177 13.177 -7.872 33.562 1.00 60.00 C +ANISOU 1412 CG2 ILE A 177 10684 5032 7079 906 -1178 -114 C +ATOM 1413 CD1 ILE A 177 16.109 -7.014 33.972 1.00 61.20 C +ANISOU 1413 CD1 ILE A 177 10529 5199 7522 1255 -1272 -142 C +ATOM 1414 N ILE A 178 12.640 -10.145 30.907 1.00 59.81 N +ANISOU 1414 N ILE A 178 10822 4736 7165 1010 -1109 -422 N +ATOM 1415 CA ILE A 178 11.380 -10.336 30.180 1.00 59.61 C +ANISOU 1415 CA ILE A 178 10880 4748 7020 867 -1042 -466 C +ATOM 1416 C ILE A 178 10.878 -11.783 30.273 1.00 62.11 C +ANISOU 1416 C ILE A 178 11399 4828 7369 805 -1157 -461 C +ATOM 1417 O ILE A 178 9.695 -12.006 30.513 1.00 61.16 O +ANISOU 1417 O ILE A 178 11379 4710 7149 617 -1172 -399 O +ATOM 1418 CB ILE A 178 11.519 -9.901 28.701 1.00 58.25 C +ANISOU 1418 CB ILE A 178 10619 4687 6824 940 -891 -630 C +ATOM 1419 CG1 ILE A 178 11.672 -8.380 28.621 1.00 56.38 C +ANISOU 1419 CG1 ILE A 178 10209 4696 6514 941 -777 -612 C +ATOM 1420 CG2 ILE A 178 10.325 -10.354 27.884 1.00 57.97 C +ANISOU 1420 CG2 ILE A 178 10696 4639 6689 807 -867 -688 C +ATOM 1421 CD1 ILE A 178 12.276 -7.871 27.325 1.00 56.32 C +ANISOU 1421 CD1 ILE A 178 10106 4786 6505 1047 -634 -761 C +ATOM 1422 N GLU A 179 11.775 -12.754 30.088 1.00 65.67 N +ANISOU 1422 N GLU A 179 11904 5072 7973 961 -1235 -531 N +ATOM 1423 CA GLU A 179 11.427 -14.189 30.194 1.00 68.92 C +ANISOU 1423 CA GLU A 179 12524 5224 8438 920 -1362 -528 C +ATOM 1424 C GLU A 179 10.832 -14.534 31.561 1.00 69.40 C +ANISOU 1424 C GLU A 179 12725 5199 8442 753 -1500 -335 C +ATOM 1425 O GLU A 179 9.885 -15.314 31.664 1.00 69.31 O +ANISOU 1425 O GLU A 179 12881 5078 8375 594 -1551 -299 O +ATOM 1426 CB GLU A 179 12.646 -15.084 29.882 1.00 71.88 C +ANISOU 1426 CB GLU A 179 12911 5379 9021 1146 -1432 -633 C +ATOM 1427 CG GLU A 179 12.947 -15.215 28.378 1.00 73.45 C +ANISOU 1427 CG GLU A 179 13061 5591 9256 1263 -1286 -855 C +ATOM 1428 CD GLU A 179 14.271 -15.912 28.065 1.00 76.51 C +ANISOU 1428 CD GLU A 179 13405 5790 9874 1510 -1313 -984 C +ATOM 1429 OE1 GLU A 179 14.694 -16.774 28.860 1.00 79.98 O +ANISOU 1429 OE1 GLU A 179 13930 5999 10458 1574 -1494 -913 O +ATOM 1430 OE2 GLU A 179 14.889 -15.610 27.015 1.00 77.49 O +ANISOU 1430 OE2 GLU A 179 13413 5987 10039 1636 -1153 -1159 O +ATOM 1431 N GLU A 180 11.384 -13.924 32.600 1.00 70.36 N +ANISOU 1431 N GLU A 180 12786 5377 8570 774 -1556 -215 N +ATOM 1432 CA GLU A 180 10.873 -14.067 33.962 1.00 72.18 C +ANISOU 1432 CA GLU A 180 13155 5556 8713 600 -1666 -28 C +ATOM 1433 C GLU A 180 9.431 -13.531 34.081 1.00 70.40 C +ANISOU 1433 C GLU A 180 12942 5501 8304 355 -1548 19 C +ATOM 1434 O GLU A 180 8.579 -14.155 34.722 1.00 71.59 O +ANISOU 1434 O GLU A 180 13263 5556 8381 164 -1603 115 O +ATOM 1435 CB GLU A 180 11.813 -13.331 34.924 1.00 73.89 C +ANISOU 1435 CB GLU A 180 13286 5831 8957 678 -1732 69 C +ATOM 1436 CG GLU A 180 11.744 -13.754 36.379 1.00 77.45 C +ANISOU 1436 CG GLU A 180 13924 6146 9355 554 -1906 257 C +ATOM 1437 CD GLU A 180 12.909 -13.186 37.207 1.00 80.40 C +ANISOU 1437 CD GLU A 180 14221 6534 9792 671 -2018 335 C +ATOM 1438 OE1 GLU A 180 13.309 -12.017 36.958 1.00 79.40 O +ANISOU 1438 OE1 GLU A 180 13887 6622 9659 743 -1901 286 O +ATOM 1439 OE2 GLU A 180 13.434 -13.914 38.098 1.00 84.10 O +ANISOU 1439 OE2 GLU A 180 14842 6789 10320 687 -2237 449 O +ATOM 1440 N MET A 181 9.163 -12.391 33.438 1.00 67.14 N +ANISOU 1440 N MET A 181 12347 5333 7830 360 -1385 -50 N +ATOM 1441 CA MET A 181 7.853 -11.737 33.515 1.00 64.85 C +ANISOU 1441 CA MET A 181 12022 5217 7400 156 -1273 -17 C +ATOM 1442 C MET A 181 6.805 -12.452 32.682 1.00 64.31 C +ANISOU 1442 C MET A 181 12028 5094 7311 44 -1250 -90 C +ATOM 1443 O MET A 181 5.618 -12.288 32.920 1.00 63.30 O +ANISOU 1443 O MET A 181 11909 5042 7098 -153 -1198 -46 O +ATOM 1444 CB MET A 181 7.934 -10.282 33.059 1.00 63.24 C +ANISOU 1444 CB MET A 181 11603 5271 7154 210 -1131 -67 C +ATOM 1445 CG MET A 181 8.944 -9.419 33.818 1.00 63.30 C +ANISOU 1445 CG MET A 181 11516 5357 7176 310 -1142 -5 C +ATOM 1446 SD MET A 181 8.580 -9.025 35.535 1.00 63.12 S +ANISOU 1446 SD MET A 181 11573 5363 7044 136 -1179 172 S +ATOM 1447 CE MET A 181 9.486 -10.314 36.385 1.00 66.34 C +ANISOU 1447 CE MET A 181 12182 5487 7536 193 -1403 264 C +ATOM 1448 N ASP A 182 7.234 -13.228 31.696 1.00 65.34 N +ANISOU 1448 N ASP A 182 12205 5093 7526 167 -1284 -210 N +ATOM 1449 CA ASP A 182 6.320 -14.111 30.969 1.00 66.83 C +ANISOU 1449 CA ASP A 182 12508 5183 7701 56 -1298 -277 C +ATOM 1450 C ASP A 182 5.799 -15.234 31.845 1.00 68.73 C +ANISOU 1450 C ASP A 182 12955 5215 7940 -100 -1417 -170 C +ATOM 1451 O ASP A 182 4.628 -15.608 31.739 1.00 69.26 O +ANISOU 1451 O ASP A 182 13089 5274 7953 -297 -1405 -160 O +ATOM 1452 CB ASP A 182 6.995 -14.697 29.731 1.00 68.43 C +ANISOU 1452 CB ASP A 182 12734 5278 7987 229 -1300 -443 C +ATOM 1453 CG ASP A 182 7.059 -13.706 28.580 1.00 67.56 C +ANISOU 1453 CG ASP A 182 12464 5375 7829 303 -1163 -565 C +ATOM 1454 OD1 ASP A 182 6.665 -12.538 28.772 1.00 66.17 O +ANISOU 1454 OD1 ASP A 182 12149 5417 7575 242 -1084 -513 O +ATOM 1455 OD2 ASP A 182 7.494 -14.096 27.478 1.00 69.25 O +ANISOU 1455 OD2 ASP A 182 12705 5528 8079 415 -1134 -714 O +ATOM 1456 N ARG A 183 6.658 -15.757 32.717 1.00 70.55 N +ANISOU 1456 N ARG A 183 13291 5279 8237 -23 -1539 -85 N +ATOM 1457 CA ARG A 183 6.252 -16.795 33.663 1.00 72.85 C +ANISOU 1457 CA ARG A 183 13807 5358 8513 -180 -1667 39 C +ATOM 1458 C ARG A 183 5.179 -16.300 34.648 1.00 72.85 C +ANISOU 1458 C ARG A 183 13821 5486 8370 -440 -1602 172 C +ATOM 1459 O ARG A 183 4.462 -17.112 35.217 1.00 74.89 O +ANISOU 1459 O ARG A 183 14260 5609 8586 -638 -1658 256 O +ATOM 1460 CB ARG A 183 7.472 -17.353 34.405 1.00 74.30 C +ANISOU 1460 CB ARG A 183 14094 5335 8799 -30 -1835 112 C +ATOM 1461 N ARG A 184 5.067 -14.982 34.838 1.00 71.60 N +ANISOU 1461 N ARG A 184 13477 5582 8144 -446 -1475 183 N +ATOM 1462 CA ARG A 184 3.988 -14.384 35.641 1.00 71.59 C +ANISOU 1462 CA ARG A 184 13451 5728 8020 -684 -1372 273 C +ATOM 1463 C ARG A 184 2.798 -13.879 34.805 1.00 69.00 C +ANISOU 1463 C ARG A 184 12972 5577 7668 -792 -1234 183 C +ATOM 1464 O ARG A 184 1.882 -13.279 35.359 1.00 67.02 O +ANISOU 1464 O ARG A 184 12653 5466 7345 -969 -1128 231 O +ATOM 1465 CB ARG A 184 4.522 -13.214 36.494 1.00 72.51 C +ANISOU 1465 CB ARG A 184 13466 6005 8077 -640 -1320 344 C +ATOM 1466 CG ARG A 184 5.586 -13.580 37.519 1.00 75.59 C +ANISOU 1466 CG ARG A 184 14003 6240 8474 -572 -1472 459 C +ATOM 1467 CD ARG A 184 5.975 -12.368 38.388 1.00 76.42 C +ANISOU 1467 CD ARG A 184 14017 6517 8500 -566 -1417 528 C +ATOM 1468 NE ARG A 184 7.228 -12.599 39.132 1.00 78.90 N +ANISOU 1468 NE ARG A 184 14430 6695 8853 -443 -1590 614 N +ATOM 1469 CZ ARG A 184 7.735 -11.805 40.080 1.00 78.15 C +ANISOU 1469 CZ ARG A 184 14324 6682 8687 -447 -1606 699 C +ATOM 1470 NH1 ARG A 184 7.112 -10.688 40.450 1.00 77.31 N +ANISOU 1470 NH1 ARG A 184 14117 6795 8462 -565 -1440 705 N +ATOM 1471 NH2 ARG A 184 8.888 -12.123 40.663 1.00 79.27 N +ANISOU 1471 NH2 ARG A 184 14553 6678 8887 -327 -1799 774 N +ATOM 1472 N GLN A 185 2.813 -14.101 33.489 1.00 68.47 N +ANISOU 1472 N GLN A 185 12852 5500 7664 -688 -1239 49 N +ATOM 1473 CA GLN A 185 1.680 -13.735 32.604 1.00 67.36 C +ANISOU 1473 CA GLN A 185 12588 5497 7508 -792 -1153 -34 C +ATOM 1474 C GLN A 185 1.591 -12.211 32.354 1.00 63.75 C +ANISOU 1474 C GLN A 185 11893 5306 7021 -734 -1030 -65 C +ATOM 1475 O GLN A 185 0.512 -11.690 32.038 1.00 62.80 O +ANISOU 1475 O GLN A 185 11650 5322 6886 -856 -958 -91 O +ATOM 1476 CB GLN A 185 0.341 -14.235 33.199 1.00 70.17 C +ANISOU 1476 CB GLN A 185 13011 5820 7829 -1076 -1134 33 C +ATOM 1477 CG GLN A 185 -0.675 -14.732 32.182 1.00 71.37 C +ANISOU 1477 CG GLN A 185 13150 5953 8013 -1186 -1147 -58 C +ATOM 1478 CD GLN A 185 -0.494 -16.211 31.860 1.00 73.87 C +ANISOU 1478 CD GLN A 185 13694 6002 8370 -1198 -1279 -82 C +ATOM 1479 OE1 GLN A 185 0.252 -16.935 32.541 1.00 74.49 O +ANISOU 1479 OE1 GLN A 185 13949 5895 8459 -1153 -1364 -11 O +ATOM 1480 NE2 GLN A 185 -1.187 -16.675 30.815 1.00 74.38 N +ANISOU 1480 NE2 GLN A 185 13764 6034 8460 -1261 -1311 -182 N +ATOM 1481 N GLU A 186 2.714 -11.500 32.480 1.00 60.05 N +ANISOU 1481 N GLU A 186 11355 4903 6558 -548 -1015 -63 N +ATOM 1482 CA GLU A 186 2.705 -10.044 32.396 1.00 57.18 C +ANISOU 1482 CA GLU A 186 10790 4773 6163 -499 -906 -75 C +ATOM 1483 C GLU A 186 2.644 -9.565 30.957 1.00 54.43 C +ANISOU 1483 C GLU A 186 10327 4523 5829 -402 -873 -200 C +ATOM 1484 O GLU A 186 3.509 -9.877 30.154 1.00 53.91 O +ANISOU 1484 O GLU A 186 10297 4392 5795 -243 -906 -281 O +ATOM 1485 CB GLU A 186 3.940 -9.459 33.078 1.00 57.43 C +ANISOU 1485 CB GLU A 186 10794 4831 6193 -352 -910 -23 C +ATOM 1486 CG GLU A 186 4.060 -9.827 34.558 1.00 59.48 C +ANISOU 1486 CG GLU A 186 11188 4996 6413 -454 -959 111 C +ATOM 1487 CD GLU A 186 3.264 -8.899 35.474 1.00 59.67 C +ANISOU 1487 CD GLU A 186 11138 5179 6354 -615 -846 180 C +ATOM 1488 OE1 GLU A 186 2.459 -8.081 34.968 1.00 59.46 O +ANISOU 1488 OE1 GLU A 186 10949 5318 6324 -660 -738 124 O +ATOM 1489 OE2 GLU A 186 3.451 -8.978 36.708 1.00 62.07 O +ANISOU 1489 OE2 GLU A 186 11551 5435 6596 -698 -867 288 O +ATOM 1490 N LYS A 187 1.604 -8.807 30.646 1.00 51.83 N +ANISOU 1490 N LYS A 187 9865 4349 5479 -504 -808 -216 N +ATOM 1491 CA LYS A 187 1.414 -8.237 29.325 1.00 50.16 C +ANISOU 1491 CA LYS A 187 9555 4240 5262 -439 -792 -317 C +ATOM 1492 C LYS A 187 1.563 -6.701 29.295 1.00 45.76 C +ANISOU 1492 C LYS A 187 8816 3886 4683 -369 -707 -309 C +ATOM 1493 O LYS A 187 1.729 -6.132 28.230 1.00 44.46 O +ANISOU 1493 O LYS A 187 8591 3801 4500 -284 -698 -381 O +ATOM 1494 CB LYS A 187 0.026 -8.626 28.796 1.00 52.26 C +ANISOU 1494 CB LYS A 187 9812 4501 5541 -611 -826 -349 C +ATOM 1495 CG LYS A 187 -0.245 -10.122 28.724 1.00 54.83 C +ANISOU 1495 CG LYS A 187 10320 4623 5888 -703 -914 -363 C +ATOM 1496 CD LYS A 187 0.685 -10.835 27.743 1.00 56.24 C +ANISOU 1496 CD LYS A 187 10631 4673 6065 -552 -974 -461 C +ATOM 1497 CE LYS A 187 0.318 -12.299 27.584 1.00 58.56 C +ANISOU 1497 CE LYS A 187 11110 4754 6384 -649 -1068 -487 C +ATOM 1498 NZ LYS A 187 -0.985 -12.433 26.872 1.00 59.50 N +ANISOU 1498 NZ LYS A 187 11200 4906 6499 -816 -1107 -531 N +ATOM 1499 N ARG A 188 1.519 -6.051 30.450 1.00 42.78 N +ANISOU 1499 N ARG A 188 8372 3583 4298 -411 -645 -224 N +ATOM 1500 CA ARG A 188 1.583 -4.595 30.540 1.00 39.94 C +ANISOU 1500 CA ARG A 188 7847 3401 3923 -359 -565 -214 C +ATOM 1501 C ARG A 188 2.865 -4.098 31.204 1.00 38.61 C +ANISOU 1501 C ARG A 188 7681 3251 3736 -230 -539 -172 C +ATOM 1502 O ARG A 188 3.237 -4.530 32.280 1.00 39.12 O +ANISOU 1502 O ARG A 188 7832 3238 3791 -259 -557 -100 O +ATOM 1503 CB ARG A 188 0.360 -4.072 31.275 1.00 39.20 C +ANISOU 1503 CB ARG A 188 7650 3396 3845 -522 -497 -171 C +ATOM 1504 CG ARG A 188 -0.937 -4.508 30.620 1.00 39.52 C +ANISOU 1504 CG ARG A 188 7656 3427 3933 -654 -532 -215 C +ATOM 1505 CD ARG A 188 -2.134 -4.170 31.474 1.00 39.58 C +ANISOU 1505 CD ARG A 188 7554 3501 3983 -826 -451 -180 C +ATOM 1506 NE ARG A 188 -3.297 -3.901 30.653 1.00 39.96 N +ANISOU 1506 NE ARG A 188 7463 3612 4107 -896 -478 -236 N +ATOM 1507 CZ ARG A 188 -4.518 -3.661 31.114 1.00 40.92 C +ANISOU 1507 CZ ARG A 188 7447 3790 4308 -1048 -416 -234 C +ATOM 1508 NH1 ARG A 188 -4.779 -3.692 32.432 1.00 41.68 N +ANISOU 1508 NH1 ARG A 188 7547 3890 4396 -1166 -299 -182 N +ATOM 1509 NH2 ARG A 188 -5.496 -3.414 30.253 1.00 41.25 N +ANISOU 1509 NH2 ARG A 188 7351 3880 4439 -1090 -474 -287 N +ATOM 1510 N TYR A 189 3.539 -3.182 30.528 1.00 37.33 N +ANISOU 1510 N TYR A 189 7428 3189 3567 -95 -508 -215 N +ATOM 1511 CA TYR A 189 4.847 -2.719 30.918 1.00 36.66 C +ANISOU 1511 CA TYR A 189 7327 3121 3480 38 -493 -194 C +ATOM 1512 C TYR A 189 4.894 -1.195 30.944 1.00 35.46 C +ANISOU 1512 C TYR A 189 7027 3139 3306 71 -414 -184 C +ATOM 1513 O TYR A 189 4.628 -0.566 29.942 1.00 34.34 O +ANISOU 1513 O TYR A 189 6812 3080 3154 99 -392 -238 O +ATOM 1514 CB TYR A 189 5.845 -3.167 29.895 1.00 36.86 C +ANISOU 1514 CB TYR A 189 7392 3085 3528 185 -519 -276 C +ATOM 1515 CG TYR A 189 6.303 -4.572 29.995 1.00 38.21 C +ANISOU 1515 CG TYR A 189 7705 3068 3745 215 -599 -289 C +ATOM 1516 CD1 TYR A 189 5.550 -5.629 29.484 1.00 39.52 C +ANISOU 1516 CD1 TYR A 189 7978 3124 3914 135 -650 -329 C +ATOM 1517 CD2 TYR A 189 7.539 -4.851 30.522 1.00 38.71 C +ANISOU 1517 CD2 TYR A 189 7794 3052 3862 334 -636 -268 C +ATOM 1518 CE1 TYR A 189 6.015 -6.938 29.564 1.00 40.91 C +ANISOU 1518 CE1 TYR A 189 8296 3105 4141 172 -730 -345 C +ATOM 1519 CE2 TYR A 189 8.002 -6.137 30.607 1.00 40.43 C +ANISOU 1519 CE2 TYR A 189 8139 3078 4144 380 -725 -281 C +ATOM 1520 CZ TYR A 189 7.251 -7.171 30.112 1.00 41.34 C +ANISOU 1520 CZ TYR A 189 8371 3078 4257 303 -766 -322 C +ATOM 1521 OH TYR A 189 7.803 -8.417 30.218 1.00 43.32 O +ANISOU 1521 OH TYR A 189 8752 3122 4584 363 -859 -338 O +ATOM 1522 N LEU A 190 5.225 -0.625 32.100 1.00 35.79 N +ANISOU 1522 N LEU A 190 7044 3219 3334 58 -384 -114 N +ATOM 1523 CA LEU A 190 5.570 0.787 32.209 1.00 35.10 C +ANISOU 1523 CA LEU A 190 6836 3269 3230 112 -319 -106 C +ATOM 1524 C LEU A 190 7.075 0.895 32.181 1.00 35.50 C +ANISOU 1524 C LEU A 190 6889 3302 3297 256 -340 -109 C +ATOM 1525 O LEU A 190 7.745 0.293 32.998 1.00 35.32 O +ANISOU 1525 O LEU A 190 6941 3188 3289 273 -397 -63 O +ATOM 1526 CB LEU A 190 5.046 1.364 33.509 1.00 35.03 C +ANISOU 1526 CB LEU A 190 6806 3309 3194 4 -266 -40 C +ATOM 1527 CG LEU A 190 5.338 2.833 33.812 1.00 33.96 C +ANISOU 1527 CG LEU A 190 6560 3299 3041 44 -198 -30 C +ATOM 1528 CD1 LEU A 190 4.732 3.725 32.769 1.00 33.25 C +ANISOU 1528 CD1 LEU A 190 6349 3308 2974 68 -160 -84 C +ATOM 1529 CD2 LEU A 190 4.749 3.183 35.172 1.00 34.49 C +ANISOU 1529 CD2 LEU A 190 6641 3390 3072 -81 -137 21 C +ATOM 1530 N ILE A 191 7.602 1.655 31.223 1.00 36.33 N +ANISOU 1530 N ILE A 191 6910 3487 3403 352 -301 -164 N +ATOM 1531 CA ILE A 191 9.038 1.795 31.047 1.00 37.96 C +ANISOU 1531 CA ILE A 191 7091 3689 3644 487 -302 -185 C +ATOM 1532 C ILE A 191 9.448 3.249 31.290 1.00 38.39 C +ANISOU 1532 C ILE A 191 7035 3872 3678 511 -243 -160 C +ATOM 1533 O ILE A 191 9.185 4.132 30.476 1.00 38.66 O +ANISOU 1533 O ILE A 191 7003 4001 3682 516 -187 -193 O +ATOM 1534 CB ILE A 191 9.461 1.351 29.648 1.00 38.74 C +ANISOU 1534 CB ILE A 191 7203 3760 3756 572 -286 -283 C +ATOM 1535 CG1 ILE A 191 9.192 -0.145 29.470 1.00 40.49 C +ANISOU 1535 CG1 ILE A 191 7546 3831 4007 558 -352 -314 C +ATOM 1536 CG2 ILE A 191 10.938 1.642 29.405 1.00 39.09 C +ANISOU 1536 CG2 ILE A 191 7183 3818 3850 706 -253 -320 C +ATOM 1537 CD1 ILE A 191 9.437 -0.635 28.059 1.00 41.22 C +ANISOU 1537 CD1 ILE A 191 7677 3890 4095 621 -326 -428 C +ATOM 1538 N ASP A 192 10.105 3.468 32.424 1.00 40.14 N +ANISOU 1538 N ASP A 192 7252 4085 3914 519 -270 -98 N +ATOM 1539 CA ASP A 192 10.475 4.790 32.931 1.00 40.37 C +ANISOU 1539 CA ASP A 192 7198 4218 3923 522 -227 -65 C +ATOM 1540 C ASP A 192 11.983 4.854 32.812 1.00 40.95 C +ANISOU 1540 C ASP A 192 7220 4280 4058 641 -249 -81 C +ATOM 1541 O ASP A 192 12.681 4.769 33.808 1.00 42.78 O +ANISOU 1541 O ASP A 192 7465 4473 4316 653 -315 -28 O +ATOM 1542 CB ASP A 192 10.007 4.877 34.403 1.00 41.46 C +ANISOU 1542 CB ASP A 192 7392 4341 4018 415 -249 13 C +ATOM 1543 CG ASP A 192 10.448 6.162 35.149 1.00 42.03 C +ANISOU 1543 CG ASP A 192 7406 4500 4063 407 -218 48 C +ATOM 1544 OD1 ASP A 192 10.618 7.252 34.545 1.00 42.37 O +ANISOU 1544 OD1 ASP A 192 7352 4638 4109 448 -157 17 O +ATOM 1545 OD2 ASP A 192 10.576 6.068 36.397 1.00 42.80 O +ANISOU 1545 OD2 ASP A 192 7576 4561 4123 345 -259 111 O +ATOM 1546 N CYS A 193 12.488 4.976 31.590 1.00 41.36 N +ANISOU 1546 N CYS A 193 7216 4363 4134 722 -196 -157 N +ATOM 1547 CA CYS A 193 13.921 4.994 31.335 1.00 42.77 C +ANISOU 1547 CA CYS A 193 7321 4535 4395 835 -191 -194 C +ATOM 1548 C CYS A 193 14.286 6.160 30.455 1.00 42.09 C +ANISOU 1548 C CYS A 193 7142 4567 4281 856 -87 -235 C +ATOM 1549 O CYS A 193 13.405 6.862 29.960 1.00 40.32 O +ANISOU 1549 O CYS A 193 6928 4415 3975 793 -39 -234 O +ATOM 1550 CB CYS A 193 14.349 3.707 30.626 1.00 45.45 C +ANISOU 1550 CB CYS A 193 7698 4763 4804 918 -208 -270 C +ATOM 1551 SG CYS A 193 14.134 2.224 31.613 1.00 48.69 S +ANISOU 1551 SG CYS A 193 8232 5000 5266 906 -351 -218 S +ATOM 1552 N GLU A 194 15.592 6.352 30.265 1.00 43.96 N +ANISOU 1552 N GLU A 194 7288 4817 4596 941 -60 -270 N +ATOM 1553 CA GLU A 194 16.111 7.267 29.238 1.00 45.34 C +ANISOU 1553 CA GLU A 194 7388 5090 4749 960 56 -325 C +ATOM 1554 C GLU A 194 15.763 6.711 27.872 1.00 45.82 C +ANISOU 1554 C GLU A 194 7512 5136 4762 970 126 -415 C +ATOM 1555 O GLU A 194 15.590 5.503 27.727 1.00 45.98 O +ANISOU 1555 O GLU A 194 7599 5056 4815 1002 89 -455 O +ATOM 1556 CB GLU A 194 17.640 7.425 29.324 1.00 47.10 C +ANISOU 1556 CB GLU A 194 7483 5320 5091 1045 81 -357 C +ATOM 1557 CG GLU A 194 18.157 8.194 30.535 1.00 48.22 C +ANISOU 1557 CG GLU A 194 7554 5493 5273 1027 11 -275 C +ATOM 1558 CD GLU A 194 17.702 9.657 30.577 1.00 48.36 C +ANISOU 1558 CD GLU A 194 7563 5622 5189 941 62 -228 C +ATOM 1559 OE1 GLU A 194 17.794 10.374 29.538 1.00 49.86 O +ANISOU 1559 OE1 GLU A 194 7725 5886 5330 927 172 -271 O +ATOM 1560 OE2 GLU A 194 17.255 10.099 31.666 1.00 47.72 O +ANISOU 1560 OE2 GLU A 194 7513 5545 5072 881 -6 -151 O +ATOM 1561 N VAL A 195 15.702 7.600 26.879 1.00 45.67 N +ANISOU 1561 N VAL A 195 7487 5206 4657 937 222 -444 N +ATOM 1562 CA VAL A 195 15.363 7.239 25.500 1.00 46.69 C +ANISOU 1562 CA VAL A 195 7703 5332 4705 924 290 -527 C +ATOM 1563 C VAL A 195 16.217 6.090 24.955 1.00 48.87 C +ANISOU 1563 C VAL A 195 7982 5528 5058 1013 343 -639 C +ATOM 1564 O VAL A 195 15.681 5.103 24.440 1.00 48.66 O +ANISOU 1564 O VAL A 195 8059 5425 5003 1012 324 -693 O +ATOM 1565 CB VAL A 195 15.457 8.461 24.550 1.00 46.24 C +ANISOU 1565 CB VAL A 195 7646 5380 4543 873 385 -535 C +ATOM 1566 CG1 VAL A 195 15.403 8.032 23.105 1.00 47.74 C +ANISOU 1566 CG1 VAL A 195 7939 5560 4638 858 466 -632 C +ATOM 1567 CG2 VAL A 195 14.312 9.412 24.806 1.00 45.94 C +ANISOU 1567 CG2 VAL A 195 7636 5390 4427 789 319 -444 C +ATOM 1568 N GLU A 196 17.536 6.214 25.076 1.00 51.26 N +ANISOU 1568 N GLU A 196 8162 5842 5469 1089 408 -680 N +ATOM 1569 CA GLU A 196 18.451 5.229 24.483 1.00 54.16 C +ANISOU 1569 CA GLU A 196 8503 6137 5937 1186 486 -807 C +ATOM 1570 C GLU A 196 18.244 3.853 25.095 1.00 52.45 C +ANISOU 1570 C GLU A 196 8335 5773 5821 1249 365 -812 C +ATOM 1571 O GLU A 196 18.407 2.845 24.423 1.00 53.56 O +ANISOU 1571 O GLU A 196 8529 5825 5996 1305 406 -920 O +ATOM 1572 CB GLU A 196 19.915 5.649 24.653 1.00 58.60 C +ANISOU 1572 CB GLU A 196 8886 6737 6640 1258 566 -846 C +ATOM 1573 CG GLU A 196 20.271 6.957 23.946 1.00 61.54 C +ANISOU 1573 CG GLU A 196 9216 7246 6919 1187 707 -854 C +ATOM 1574 CD GLU A 196 20.201 8.186 24.865 1.00 64.09 C +ANISOU 1574 CD GLU A 196 9472 7649 7229 1129 636 -725 C +ATOM 1575 OE1 GLU A 196 19.266 8.299 25.725 1.00 63.69 O +ANISOU 1575 OE1 GLU A 196 9482 7582 7135 1089 499 -620 O +ATOM 1576 OE2 GLU A 196 21.091 9.051 24.713 1.00 65.74 O +ANISOU 1576 OE2 GLU A 196 9569 7936 7471 1116 729 -737 O +ATOM 1577 N ARG A 197 17.882 3.814 26.372 1.00 49.53 N +ANISOU 1577 N ARG A 197 7960 5369 5489 1233 218 -696 N +ATOM 1578 CA ARG A 197 17.611 2.558 27.024 1.00 49.31 C +ANISOU 1578 CA ARG A 197 8004 5194 5537 1269 90 -678 C +ATOM 1579 C ARG A 197 16.220 2.017 26.652 1.00 47.02 C +ANISOU 1579 C ARG A 197 7876 4865 5122 1181 56 -671 C +ATOM 1580 O ARG A 197 16.032 0.797 26.537 1.00 47.07 O +ANISOU 1580 O ARG A 197 7970 4739 5172 1213 5 -716 O +ATOM 1581 CB ARG A 197 17.786 2.695 28.536 1.00 50.11 C +ANISOU 1581 CB ARG A 197 8065 5268 5707 1266 -51 -555 C +ATOM 1582 CG ARG A 197 17.619 1.372 29.266 1.00 52.18 C +ANISOU 1582 CG ARG A 197 8417 5361 6047 1298 -196 -524 C +ATOM 1583 CD ARG A 197 18.131 1.443 30.687 1.00 53.81 C +ANISOU 1583 CD ARG A 197 8585 5524 6333 1310 -341 -415 C +ATOM 1584 NE ARG A 197 19.592 1.411 30.706 1.00 55.91 N +ANISOU 1584 NE ARG A 197 8697 5763 6781 1441 -351 -466 N +ATOM 1585 CZ ARG A 197 20.379 2.443 31.003 1.00 56.40 C +ANISOU 1585 CZ ARG A 197 8618 5927 6884 1451 -329 -443 C +ATOM 1586 NH1 ARG A 197 19.870 3.640 31.358 1.00 54.68 N +ANISOU 1586 NH1 ARG A 197 8406 5840 6529 1339 -299 -367 N +ATOM 1587 NH2 ARG A 197 21.694 2.260 30.961 1.00 57.90 N +ANISOU 1587 NH2 ARG A 197 8651 6078 7269 1574 -341 -502 N +ATOM 1588 N ILE A 198 15.248 2.898 26.447 1.00 44.09 N +ANISOU 1588 N ILE A 198 7540 4597 4612 1073 75 -619 N +ATOM 1589 CA ILE A 198 13.967 2.450 25.909 1.00 43.78 C +ANISOU 1589 CA ILE A 198 7631 4532 4471 988 46 -628 C +ATOM 1590 C ILE A 198 14.182 1.743 24.548 1.00 45.61 C +ANISOU 1590 C ILE A 198 7939 4715 4673 1024 124 -764 C +ATOM 1591 O ILE A 198 13.671 0.640 24.357 1.00 47.09 O +ANISOU 1591 O ILE A 198 8234 4791 4864 1015 70 -803 O +ATOM 1592 CB ILE A 198 12.933 3.588 25.798 1.00 41.88 C +ANISOU 1592 CB ILE A 198 7391 4408 4112 879 48 -560 C +ATOM 1593 CG1 ILE A 198 12.495 4.038 27.187 1.00 41.02 C +ANISOU 1593 CG1 ILE A 198 7238 4319 4026 830 -24 -444 C +ATOM 1594 CG2 ILE A 198 11.706 3.116 25.038 1.00 42.14 C +ANISOU 1594 CG2 ILE A 198 7540 4413 4058 799 13 -587 C +ATOM 1595 CD1 ILE A 198 11.751 5.355 27.250 1.00 40.23 C +ANISOU 1595 CD1 ILE A 198 7097 4333 3852 753 -7 -385 C +ATOM 1596 N ASN A 199 14.965 2.346 23.638 1.00 45.22 N +ANISOU 1596 N ASN A 199 7846 4742 4592 1056 257 -841 N +ATOM 1597 CA ASN A 199 15.257 1.723 22.340 1.00 46.82 C +ANISOU 1597 CA ASN A 199 8134 4904 4751 1081 360 -986 C +ATOM 1598 C ASN A 199 15.954 0.384 22.481 1.00 47.98 C +ANISOU 1598 C ASN A 199 8283 4900 5047 1195 354 -1078 C +ATOM 1599 O ASN A 199 15.587 -0.577 21.820 1.00 49.63 O +ANISOU 1599 O ASN A 199 8620 5013 5224 1192 354 -1166 O +ATOM 1600 CB ASN A 199 16.098 2.646 21.438 1.00 47.28 C +ANISOU 1600 CB ASN A 199 8141 5073 4750 1084 528 -1052 C +ATOM 1601 CG ASN A 199 15.382 3.928 21.083 1.00 45.85 C +ANISOU 1601 CG ASN A 199 7992 5019 4410 970 526 -971 C +ATOM 1602 OD1 ASN A 199 14.182 3.935 20.859 1.00 44.81 O +ANISOU 1602 OD1 ASN A 199 7965 4884 4174 884 435 -926 O +ATOM 1603 ND2 ASN A 199 16.125 5.028 21.046 1.00 45.97 N +ANISOU 1603 ND2 ASN A 199 7909 5137 4420 968 618 -950 N +ATOM 1604 N THR A 200 16.964 0.314 23.340 1.00 48.40 N +ANISOU 1604 N THR A 200 8197 4921 5269 1298 336 -1059 N +ATOM 1605 CA THR A 200 17.623 -0.960 23.641 1.00 49.69 C +ANISOU 1605 CA THR A 200 8350 4919 5610 1420 292 -1129 C +ATOM 1606 C THR A 200 16.574 -2.004 24.070 1.00 49.13 C +ANISOU 1606 C THR A 200 8432 4715 5520 1374 140 -1080 C +ATOM 1607 O THR A 200 16.480 -3.081 23.498 1.00 50.53 O +ANISOU 1607 O THR A 200 8714 4765 5720 1407 145 -1181 O +ATOM 1608 CB THR A 200 18.702 -0.774 24.738 1.00 50.19 C +ANISOU 1608 CB THR A 200 8239 4966 5863 1520 232 -1073 C +ATOM 1609 OG1 THR A 200 19.656 0.204 24.315 1.00 50.31 O +ANISOU 1609 OG1 THR A 200 8105 5108 5903 1548 378 -1122 O +ATOM 1610 CG2 THR A 200 19.444 -2.075 25.014 1.00 52.31 C +ANISOU 1610 CG2 THR A 200 8487 5047 6341 1663 166 -1145 C +ATOM 1611 N ILE A 201 15.766 -1.662 25.059 1.00 47.72 N +ANISOU 1611 N ILE A 201 8271 4565 5295 1285 18 -930 N +ATOM 1612 CA ILE A 201 14.787 -2.598 25.594 1.00 48.11 C +ANISOU 1612 CA ILE A 201 8452 4493 5331 1221 -116 -871 C +ATOM 1613 C ILE A 201 13.845 -3.060 24.498 1.00 48.81 C +ANISOU 1613 C ILE A 201 8683 4561 5299 1142 -85 -948 C +ATOM 1614 O ILE A 201 13.571 -4.251 24.365 1.00 50.19 O +ANISOU 1614 O ILE A 201 8974 4584 5509 1149 -145 -996 O +ATOM 1615 CB ILE A 201 14.004 -1.996 26.781 1.00 46.55 C +ANISOU 1615 CB ILE A 201 8246 4357 5082 1113 -212 -707 C +ATOM 1616 CG1 ILE A 201 14.912 -1.975 28.019 1.00 47.14 C +ANISOU 1616 CG1 ILE A 201 8238 4388 5283 1186 -295 -629 C +ATOM 1617 CG2 ILE A 201 12.742 -2.798 27.087 1.00 46.19 C +ANISOU 1617 CG2 ILE A 201 8342 4223 4983 1000 -310 -657 C +ATOM 1618 CD1 ILE A 201 14.450 -1.053 29.132 1.00 45.95 C +ANISOU 1618 CD1 ILE A 201 8055 4333 5068 1090 -344 -488 C +ATOM 1619 N LEU A 202 13.361 -2.121 23.707 1.00 48.13 N +ANISOU 1619 N LEU A 202 8598 4617 5072 1065 -7 -959 N +ATOM 1620 CA LEU A 202 12.420 -2.435 22.651 1.00 48.58 C +ANISOU 1620 CA LEU A 202 8794 4665 4999 974 -3 -1021 C +ATOM 1621 C LEU A 202 13.039 -3.289 21.549 1.00 50.89 C +ANISOU 1621 C LEU A 202 9174 4863 5298 1046 86 -1192 C +ATOM 1622 O LEU A 202 12.352 -4.135 20.998 1.00 50.40 O +ANISOU 1622 O LEU A 202 9258 4708 5182 992 41 -1249 O +ATOM 1623 CB LEU A 202 11.806 -1.152 22.064 1.00 47.04 C +ANISOU 1623 CB LEU A 202 8581 4635 4655 878 36 -982 C +ATOM 1624 CG LEU A 202 10.853 -0.378 22.976 1.00 44.93 C +ANISOU 1624 CG LEU A 202 8252 4448 4371 786 -51 -835 C +ATOM 1625 CD1 LEU A 202 10.381 0.862 22.235 1.00 44.33 C +ANISOU 1625 CD1 LEU A 202 8161 4512 4169 716 -16 -816 C +ATOM 1626 CD2 LEU A 202 9.673 -1.204 23.470 1.00 44.78 C +ANISOU 1626 CD2 LEU A 202 8308 4340 4363 695 -173 -787 C +ATOM 1627 N GLU A 203 14.316 -3.082 21.235 1.00 53.61 N +ANISOU 1627 N GLU A 203 9428 5229 5712 1160 217 -1281 N +ATOM 1628 CA GLU A 203 15.004 -3.975 20.291 1.00 57.75 C +ANISOU 1628 CA GLU A 203 10022 5648 6272 1243 324 -1464 C +ATOM 1629 C GLU A 203 15.000 -5.408 20.792 1.00 58.57 C +ANISOU 1629 C GLU A 203 10192 5542 6518 1312 217 -1493 C +ATOM 1630 O GLU A 203 14.814 -6.323 19.984 1.00 61.66 O +ANISOU 1630 O GLU A 203 10728 5821 6878 1311 242 -1620 O +ATOM 1631 CB GLU A 203 16.455 -3.572 20.057 1.00 60.97 C +ANISOU 1631 CB GLU A 203 10281 6103 6783 1364 489 -1557 C +ATOM 1632 CG GLU A 203 16.658 -2.306 19.254 1.00 63.14 C +ANISOU 1632 CG GLU A 203 10523 6559 6908 1297 639 -1573 C +ATOM 1633 CD GLU A 203 17.980 -1.624 19.602 1.00 65.86 C +ANISOU 1633 CD GLU A 203 10656 6978 7389 1394 750 -1585 C +ATOM 1634 OE1 GLU A 203 18.964 -2.371 19.884 1.00 69.30 O +ANISOU 1634 OE1 GLU A 203 10992 7306 8032 1536 781 -1673 O +ATOM 1635 OE2 GLU A 203 18.031 -0.355 19.601 1.00 65.57 O +ANISOU 1635 OE2 GLU A 203 10549 7096 7265 1328 797 -1507 O +ATOM 1636 N GLN A 204 15.208 -5.611 22.101 1.00 56.74 N +ANISOU 1636 N GLN A 204 9876 5249 6433 1363 91 -1378 N +ATOM 1637 CA GLN A 204 15.202 -6.961 22.680 1.00 57.96 C +ANISOU 1637 CA GLN A 204 10108 5187 6724 1421 -36 -1381 C +ATOM 1638 C GLN A 204 13.828 -7.604 22.623 1.00 58.17 C +ANISOU 1638 C GLN A 204 10317 5143 6641 1279 -146 -1338 C +ATOM 1639 O GLN A 204 13.712 -8.811 22.420 1.00 60.92 O +ANISOU 1639 O GLN A 204 10794 5309 7045 1303 -199 -1412 O +ATOM 1640 CB GLN A 204 15.684 -6.959 24.131 1.00 57.06 C +ANISOU 1640 CB GLN A 204 9889 5026 6764 1483 -167 -1246 C +ATOM 1641 CG GLN A 204 17.129 -6.537 24.313 1.00 57.35 C +ANISOU 1641 CG GLN A 204 9732 5093 6962 1636 -97 -1290 C +ATOM 1642 CD GLN A 204 18.097 -7.304 23.425 1.00 59.67 C +ANISOU 1642 CD GLN A 204 10004 5273 7393 1786 18 -1492 C +ATOM 1643 OE1 GLN A 204 18.028 -8.551 23.277 1.00 60.56 O +ANISOU 1643 OE1 GLN A 204 10233 5186 7590 1841 -41 -1568 O +ATOM 1644 NE2 GLN A 204 19.013 -6.557 22.814 1.00 60.01 N +ANISOU 1644 NE2 GLN A 204 9898 5437 7464 1849 196 -1589 N +ATOM 1645 N VAL A 205 12.795 -6.798 22.803 1.00 56.59 N +ANISOU 1645 N VAL A 205 10120 5081 6301 1133 -182 -1224 N +ATOM 1646 CA VAL A 205 11.412 -7.264 22.677 1.00 57.05 C +ANISOU 1646 CA VAL A 205 10320 5098 6258 980 -278 -1186 C +ATOM 1647 C VAL A 205 11.178 -7.860 21.281 1.00 58.33 C +ANISOU 1647 C VAL A 205 10629 5202 6331 957 -222 -1346 C +ATOM 1648 O VAL A 205 10.602 -8.936 21.135 1.00 58.77 O +ANISOU 1648 O VAL A 205 10829 5107 6391 908 -303 -1382 O +ATOM 1649 CB VAL A 205 10.423 -6.101 22.962 1.00 55.44 C +ANISOU 1649 CB VAL A 205 10052 5073 5936 843 -300 -1060 C +ATOM 1650 CG1 VAL A 205 9.007 -6.402 22.495 1.00 55.74 C +ANISOU 1650 CG1 VAL A 205 10205 5102 5871 684 -374 -1052 C +ATOM 1651 CG2 VAL A 205 10.446 -5.757 24.445 1.00 53.72 C +ANISOU 1651 CG2 VAL A 205 9739 4877 5794 835 -369 -907 C +ATOM 1652 N VAL A 206 11.658 -7.160 20.266 1.00 58.64 N +ANISOU 1652 N VAL A 206 10645 5355 6281 985 -81 -1442 N +ATOM 1653 CA VAL A 206 11.477 -7.602 18.904 1.00 60.76 C +ANISOU 1653 CA VAL A 206 11071 5583 6430 948 -15 -1596 C +ATOM 1654 C VAL A 206 12.322 -8.854 18.657 1.00 63.41 C +ANISOU 1654 C VAL A 206 11477 5722 6893 1079 32 -1752 C +ATOM 1655 O VAL A 206 11.784 -9.887 18.289 1.00 64.14 O +ANISOU 1655 O VAL A 206 11735 5666 6966 1034 -32 -1820 O +ATOM 1656 CB VAL A 206 11.853 -6.509 17.886 1.00 60.12 C +ANISOU 1656 CB VAL A 206 10968 5670 6204 933 136 -1658 C +ATOM 1657 CG1 VAL A 206 11.794 -7.065 16.459 1.00 61.89 C +ANISOU 1657 CG1 VAL A 206 11388 5835 6289 894 217 -1836 C +ATOM 1658 CG2 VAL A 206 10.936 -5.308 18.044 1.00 58.23 C +ANISOU 1658 CG2 VAL A 206 10677 5600 5847 807 68 -1510 C +ATOM 1659 N ILE A 207 13.634 -8.749 18.880 1.00 64.78 N +ANISOU 1659 N ILE A 207 11514 5886 7210 1240 140 -1809 N +ATOM 1660 CA ILE A 207 14.566 -9.840 18.568 1.00 67.14 C +ANISOU 1660 CA ILE A 207 11846 6001 7661 1390 208 -1981 C +ATOM 1661 C ILE A 207 14.143 -11.123 19.280 1.00 67.62 C +ANISOU 1661 C ILE A 207 12010 5838 7845 1402 30 -1942 C +ATOM 1662 O ILE A 207 14.087 -12.182 18.664 1.00 70.88 O +ANISOU 1662 O ILE A 207 12576 6081 8272 1422 36 -2081 O +ATOM 1663 CB ILE A 207 16.033 -9.468 18.910 1.00 68.12 C +ANISOU 1663 CB ILE A 207 11756 6153 7971 1567 324 -2025 C +ATOM 1664 CG1 ILE A 207 16.576 -8.420 17.928 1.00 68.81 C +ANISOU 1664 CG1 ILE A 207 11780 6427 7936 1552 544 -2117 C +ATOM 1665 CG2 ILE A 207 16.926 -10.694 18.860 1.00 70.56 C +ANISOU 1665 CG2 ILE A 207 12068 6238 8500 1740 349 -2180 C +ATOM 1666 CD1 ILE A 207 17.845 -7.721 18.394 1.00 69.11 C +ANISOU 1666 CD1 ILE A 207 11571 6548 8137 1679 644 -2113 C +ATOM 1667 N LEU A 208 13.811 -11.014 20.562 1.00 66.44 N +ANISOU 1667 N LEU A 208 11793 5684 7766 1375 -126 -1754 N +ATOM 1668 CA LEU A 208 13.314 -12.143 21.337 1.00 66.81 C +ANISOU 1668 CA LEU A 208 11953 5527 7904 1352 -306 -1684 C +ATOM 1669 C LEU A 208 12.064 -12.724 20.696 1.00 67.50 C +ANISOU 1669 C LEU A 208 12244 5559 7843 1188 -362 -1714 C +ATOM 1670 O LEU A 208 11.911 -13.936 20.593 1.00 69.97 O +ANISOU 1670 O LEU A 208 12706 5658 8219 1197 -435 -1781 O +ATOM 1671 CB LEU A 208 13.007 -11.701 22.766 1.00 64.82 C +ANISOU 1671 CB LEU A 208 11616 5325 7688 1298 -441 -1465 C +ATOM 1672 CG LEU A 208 12.605 -12.757 23.787 1.00 65.59 C +ANISOU 1672 CG LEU A 208 11824 5218 7877 1263 -629 -1360 C +ATOM 1673 CD1 LEU A 208 13.691 -13.813 23.949 1.00 67.70 C +ANISOU 1673 CD1 LEU A 208 12108 5249 8363 1452 -675 -1447 C +ATOM 1674 CD2 LEU A 208 12.339 -12.056 25.109 1.00 64.33 C +ANISOU 1674 CD2 LEU A 208 11578 5158 7706 1190 -718 -1153 C +ATOM 1675 N GLY A 209 11.164 -11.856 20.267 1.00 66.74 N +ANISOU 1675 N GLY A 209 12151 5646 7561 1037 -343 -1663 N +ATOM 1676 CA GLY A 209 10.009 -12.281 19.504 1.00 67.46 C +ANISOU 1676 CA GLY A 209 12416 5707 7508 878 -397 -1703 C +ATOM 1677 C GLY A 209 8.864 -12.729 20.383 1.00 67.36 C +ANISOU 1677 C GLY A 209 12456 5630 7508 732 -570 -1555 C +ATOM 1678 O GLY A 209 9.037 -13.045 21.581 1.00 65.79 O +ANISOU 1678 O GLY A 209 12213 5350 7434 763 -654 -1440 O +ATOM 1679 N LYS A 210 7.691 -12.773 19.751 1.00 68.20 N +ANISOU 1679 N LYS A 210 12664 5769 7479 562 -626 -1562 N +ATOM 1680 CA LYS A 210 6.437 -13.159 20.394 1.00 68.84 C +ANISOU 1680 CA LYS A 210 12788 5807 7558 388 -772 -1441 C +ATOM 1681 C LYS A 210 6.014 -12.163 21.483 1.00 66.72 C +ANISOU 1681 C LYS A 210 12346 5702 7301 327 -793 -1258 C +ATOM 1682 O LYS A 210 5.200 -12.509 22.326 1.00 66.94 O +ANISOU 1682 O LYS A 210 12386 5685 7364 205 -888 -1146 O +ATOM 1683 CB LYS A 210 6.525 -14.593 20.963 1.00 71.22 C +ANISOU 1683 CB LYS A 210 13225 5849 7984 402 -868 -1446 C +ATOM 1684 N HIS A 211 6.528 -10.929 21.433 1.00 64.20 N +ANISOU 1684 N HIS A 211 11876 5568 6946 399 -696 -1234 N +ATOM 1685 CA HIS A 211 6.223 -9.918 22.438 1.00 61.79 C +ANISOU 1685 CA HIS A 211 11410 5415 6651 356 -701 -1079 C +ATOM 1686 C HIS A 211 5.621 -8.634 21.860 1.00 60.09 C +ANISOU 1686 C HIS A 211 11098 5410 6322 285 -664 -1058 C +ATOM 1687 O HIS A 211 5.968 -7.539 22.311 1.00 57.99 O +ANISOU 1687 O HIS A 211 10687 5286 6057 331 -605 -988 O +ATOM 1688 CB HIS A 211 7.476 -9.614 23.266 1.00 61.42 C +ANISOU 1688 CB HIS A 211 11260 5373 6703 514 -647 -1039 C +ATOM 1689 CG HIS A 211 7.822 -10.709 24.215 1.00 62.85 C +ANISOU 1689 CG HIS A 211 11515 5356 7009 551 -734 -995 C +ATOM 1690 ND1 HIS A 211 8.587 -11.794 23.843 1.00 65.91 N +ANISOU 1690 ND1 HIS A 211 12008 5550 7485 669 -745 -1107 N +ATOM 1691 CD2 HIS A 211 7.442 -10.937 25.494 1.00 62.28 C +ANISOU 1691 CD2 HIS A 211 11448 5235 6980 474 -821 -853 C +ATOM 1692 CE1 HIS A 211 8.696 -12.625 24.865 1.00 66.04 C +ANISOU 1692 CE1 HIS A 211 12089 5399 7604 672 -854 -1026 C +ATOM 1693 NE2 HIS A 211 7.995 -12.137 25.871 1.00 64.14 N +ANISOU 1693 NE2 HIS A 211 11800 5244 7324 544 -901 -868 N +ATOM 1694 N SER A 212 4.700 -8.780 20.901 1.00 60.07 N +ANISOU 1694 N SER A 212 11181 5413 6228 170 -717 -1112 N +ATOM 1695 CA SER A 212 3.878 -7.657 20.426 1.00 59.24 C +ANISOU 1695 CA SER A 212 10994 5481 6034 78 -735 -1071 C +ATOM 1696 C SER A 212 2.363 -7.835 20.619 1.00 59.62 C +ANISOU 1696 C SER A 212 11027 5529 6094 -103 -859 -1007 C +ATOM 1697 O SER A 212 1.780 -7.170 21.483 1.00 61.48 O +ANISOU 1697 O SER A 212 11116 5859 6383 -159 -869 -895 O +ATOM 1698 CB SER A 212 4.161 -7.351 18.973 1.00 59.32 C +ANISOU 1698 CB SER A 212 11096 5532 5908 100 -694 -1188 C +ATOM 1699 OG SER A 212 5.444 -6.799 18.839 1.00 58.68 O +ANISOU 1699 OG SER A 212 10969 5509 5816 246 -555 -1229 O +ATOM 1700 N ARG A 213 1.730 -8.697 19.825 1.00 59.90 N +ANISOU 1700 N ARG A 213 11207 5462 6088 -198 -948 -1083 N +ATOM 1701 CA ARG A 213 0.268 -8.759 19.794 1.00 59.54 C +ANISOU 1701 CA ARG A 213 11129 5433 6058 -379 -1074 -1036 C +ATOM 1702 C ARG A 213 -0.074 -9.152 21.205 1.00 58.30 C +ANISOU 1702 C ARG A 213 10895 5231 6024 -435 -1074 -933 C +ATOM 1703 O ARG A 213 0.578 -10.041 21.755 1.00 59.93 O +ANISOU 1703 O ARG A 213 11193 5299 6277 -380 -1050 -940 O +ATOM 1704 CB ARG A 213 -0.254 -9.783 18.765 1.00 61.36 C +ANISOU 1704 CB ARG A 213 11549 5533 6229 -477 -1179 -1141 C +ATOM 1705 N GLY A 214 -1.036 -8.467 21.811 1.00 56.03 N +ANISOU 1705 N GLY A 214 10442 5053 5790 -538 -1096 -839 N +ATOM 1706 CA GLY A 214 -1.443 -8.766 23.199 1.00 54.99 C +ANISOU 1706 CA GLY A 214 10243 4892 5757 -619 -1074 -740 C +ATOM 1707 C GLY A 214 -0.682 -8.031 24.301 1.00 52.26 C +ANISOU 1707 C GLY A 214 9795 4624 5436 -519 -964 -658 C +ATOM 1708 O GLY A 214 -1.141 -8.012 25.444 1.00 52.57 O +ANISOU 1708 O GLY A 214 9766 4675 5533 -606 -935 -570 O +ATOM 1709 N TYR A 215 0.440 -7.395 23.958 1.00 49.37 N +ANISOU 1709 N TYR A 215 9420 4316 5021 -352 -899 -688 N +ATOM 1710 CA TYR A 215 1.225 -6.618 24.913 1.00 47.04 C +ANISOU 1710 CA TYR A 215 9026 4099 4745 -255 -808 -616 C +ATOM 1711 C TYR A 215 0.949 -5.125 24.823 1.00 44.83 C +ANISOU 1711 C TYR A 215 8576 4008 4447 -242 -763 -583 C +ATOM 1712 O TYR A 215 0.470 -4.637 23.811 1.00 45.13 O +ANISOU 1712 O TYR A 215 8590 4113 4444 -262 -803 -626 O +ATOM 1713 CB TYR A 215 2.706 -6.860 24.681 1.00 47.05 C +ANISOU 1713 CB TYR A 215 9105 4039 4733 -79 -761 -670 C +ATOM 1714 CG TYR A 215 3.122 -8.239 25.075 1.00 48.65 C +ANISOU 1714 CG TYR A 215 9455 4043 4986 -64 -806 -685 C +ATOM 1715 CD1 TYR A 215 2.727 -9.345 24.328 1.00 50.21 C +ANISOU 1715 CD1 TYR A 215 9800 4099 5175 -121 -876 -766 C +ATOM 1716 CD2 TYR A 215 3.903 -8.454 26.206 1.00 48.66 C +ANISOU 1716 CD2 TYR A 215 9460 3981 5045 2 -794 -614 C +ATOM 1717 CE1 TYR A 215 3.094 -10.628 24.699 1.00 51.61 C +ANISOU 1717 CE1 TYR A 215 10124 4074 5411 -106 -927 -778 C +ATOM 1718 CE2 TYR A 215 4.279 -9.736 26.572 1.00 50.32 C +ANISOU 1718 CE2 TYR A 215 9816 3987 5313 19 -860 -618 C +ATOM 1719 CZ TYR A 215 3.870 -10.813 25.818 1.00 51.70 C +ANISOU 1719 CZ TYR A 215 10134 4019 5488 -31 -922 -701 C +ATOM 1720 OH TYR A 215 4.236 -12.083 26.186 1.00 54.68 O +ANISOU 1720 OH TYR A 215 10665 4177 5932 -12 -995 -704 O +ATOM 1721 N HIS A 216 1.281 -4.408 25.882 1.00 42.61 N +ANISOU 1721 N HIS A 216 8195 3801 4194 -208 -691 -505 N +ATOM 1722 CA HIS A 216 1.071 -2.964 25.947 1.00 41.01 C +ANISOU 1722 CA HIS A 216 7832 3761 3987 -189 -643 -470 C +ATOM 1723 C HIS A 216 2.243 -2.319 26.677 1.00 39.21 C +ANISOU 1723 C HIS A 216 7565 3581 3752 -69 -559 -430 C +ATOM 1724 O HIS A 216 2.504 -2.635 27.831 1.00 38.95 O +ANISOU 1724 O HIS A 216 7548 3502 3747 -84 -536 -370 O +ATOM 1725 CB HIS A 216 -0.232 -2.652 26.675 1.00 41.16 C +ANISOU 1725 CB HIS A 216 7731 3834 4073 -333 -642 -415 C +ATOM 1726 CG HIS A 216 -0.677 -1.233 26.555 1.00 40.39 C +ANISOU 1726 CG HIS A 216 7467 3883 3995 -319 -616 -398 C +ATOM 1727 ND1 HIS A 216 -1.977 -0.845 26.799 1.00 41.05 N +ANISOU 1727 ND1 HIS A 216 7413 4021 4163 -434 -628 -382 N +ATOM 1728 CD2 HIS A 216 -0.001 -0.102 26.231 1.00 39.46 C +ANISOU 1728 CD2 HIS A 216 7294 3860 3838 -206 -578 -397 C +ATOM 1729 CE1 HIS A 216 -2.084 0.467 26.628 1.00 40.37 C +ANISOU 1729 CE1 HIS A 216 7196 4048 4094 -380 -609 -372 C +ATOM 1730 NE2 HIS A 216 -0.901 0.939 26.275 1.00 39.07 N +ANISOU 1730 NE2 HIS A 216 7089 3908 3845 -247 -581 -376 N +ATOM 1731 N TYR A 217 2.967 -1.449 25.978 1.00 38.00 N +ANISOU 1731 N TYR A 217 7374 3510 3553 38 -523 -461 N +ATOM 1732 CA TYR A 217 4.085 -0.704 26.550 1.00 36.85 C +ANISOU 1732 CA TYR A 217 7172 3421 3406 148 -448 -429 C +ATOM 1733 C TYR A 217 3.688 0.757 26.703 1.00 36.24 C +ANISOU 1733 C TYR A 217 6956 3488 3323 135 -410 -386 C +ATOM 1734 O TYR A 217 3.296 1.399 25.738 1.00 36.14 O +ANISOU 1734 O TYR A 217 6914 3539 3277 131 -430 -415 O +ATOM 1735 CB TYR A 217 5.354 -0.847 25.707 1.00 36.12 C +ANISOU 1735 CB TYR A 217 7139 3305 3280 280 -415 -502 C +ATOM 1736 CG TYR A 217 5.737 -2.272 25.518 1.00 37.26 C +ANISOU 1736 CG TYR A 217 7414 3293 3448 306 -451 -560 C +ATOM 1737 CD1 TYR A 217 6.548 -2.922 26.421 1.00 37.34 C +ANISOU 1737 CD1 TYR A 217 7455 3206 3525 369 -458 -532 C +ATOM 1738 CD2 TYR A 217 5.250 -3.004 24.416 1.00 38.25 C +ANISOU 1738 CD2 TYR A 217 7647 3351 3532 265 -495 -643 C +ATOM 1739 CE1 TYR A 217 6.872 -4.261 26.245 1.00 38.84 C +ANISOU 1739 CE1 TYR A 217 7770 3231 3756 401 -504 -586 C +ATOM 1740 CE2 TYR A 217 5.573 -4.318 24.234 1.00 39.36 C +ANISOU 1740 CE2 TYR A 217 7918 3335 3701 290 -528 -706 C +ATOM 1741 CZ TYR A 217 6.380 -4.943 25.140 1.00 39.84 C +ANISOU 1741 CZ TYR A 217 7998 3294 3843 363 -530 -678 C +ATOM 1742 OH TYR A 217 6.711 -6.250 24.930 1.00 41.91 O +ANISOU 1742 OH TYR A 217 8391 3381 4149 399 -572 -743 O +ATOM 1743 N MET A 218 3.765 1.254 27.928 1.00 36.36 N +ANISOU 1743 N MET A 218 6903 3542 3370 122 -363 -318 N +ATOM 1744 CA MET A 218 3.526 2.658 28.231 1.00 36.26 C +ANISOU 1744 CA MET A 218 6762 3650 3362 123 -315 -283 C +ATOM 1745 C MET A 218 4.888 3.260 28.518 1.00 35.67 C +ANISOU 1745 C MET A 218 6676 3611 3266 235 -263 -268 C +ATOM 1746 O MET A 218 5.560 2.850 29.449 1.00 35.37 O +ANISOU 1746 O MET A 218 6672 3525 3240 255 -253 -235 O +ATOM 1747 CB MET A 218 2.601 2.793 29.436 1.00 36.80 C +ANISOU 1747 CB MET A 218 6768 3734 3479 14 -284 -232 C +ATOM 1748 CG MET A 218 2.258 4.220 29.809 1.00 37.29 C +ANISOU 1748 CG MET A 218 6696 3906 3563 15 -227 -210 C +ATOM 1749 SD MET A 218 1.129 4.294 31.220 1.00 39.72 S +ANISOU 1749 SD MET A 218 6934 4227 3928 -125 -154 -177 S +ATOM 1750 CE MET A 218 -0.329 3.531 30.534 1.00 40.00 C +ANISOU 1750 CE MET A 218 6934 4226 4035 -238 -218 -216 C +ATOM 1751 N LEU A 219 5.288 4.233 27.704 1.00 35.91 N +ANISOU 1751 N LEU A 219 6661 3720 3262 298 -240 -290 N +ATOM 1752 CA LEU A 219 6.643 4.773 27.728 1.00 36.03 C +ANISOU 1752 CA LEU A 219 6659 3768 3260 400 -187 -291 C +ATOM 1753 C LEU A 219 6.627 6.122 28.419 1.00 36.02 C +ANISOU 1753 C LEU A 219 6557 3859 3266 395 -144 -238 C +ATOM 1754 O LEU A 219 6.226 7.114 27.838 1.00 35.68 O +ANISOU 1754 O LEU A 219 6464 3886 3206 389 -139 -239 O +ATOM 1755 CB LEU A 219 7.168 4.914 26.298 1.00 36.39 C +ANISOU 1755 CB LEU A 219 6744 3833 3249 456 -172 -357 C +ATOM 1756 CG LEU A 219 7.029 3.639 25.446 1.00 37.93 C +ANISOU 1756 CG LEU A 219 7054 3936 3423 449 -210 -428 C +ATOM 1757 CD1 LEU A 219 7.525 3.862 24.029 1.00 38.81 C +ANISOU 1757 CD1 LEU A 219 7222 4071 3450 487 -176 -501 C +ATOM 1758 CD2 LEU A 219 7.743 2.444 26.074 1.00 38.51 C +ANISOU 1758 CD2 LEU A 219 7179 3898 3553 497 -215 -443 C +ATOM 1759 N ALA A 220 7.087 6.150 29.662 1.00 36.94 N +ANISOU 1759 N ALA A 220 6661 3966 3406 396 -125 -192 N +ATOM 1760 CA ALA A 220 7.019 7.344 30.505 1.00 36.74 C +ANISOU 1760 CA ALA A 220 6559 4015 3385 377 -82 -148 C +ATOM 1761 C ALA A 220 8.237 8.210 30.282 1.00 37.32 C +ANISOU 1761 C ALA A 220 6593 4140 3444 461 -49 -148 C +ATOM 1762 O ALA A 220 9.162 8.228 31.079 1.00 39.75 O +ANISOU 1762 O ALA A 220 6900 4438 3763 492 -46 -121 O +ATOM 1763 CB ALA A 220 6.922 6.951 31.973 1.00 37.16 C +ANISOU 1763 CB ALA A 220 6644 4028 3445 316 -79 -99 C +ATOM 1764 N ASN A 221 8.226 8.948 29.192 1.00 37.28 N +ANISOU 1764 N ASN A 221 6562 4189 3414 486 -34 -174 N +ATOM 1765 CA ASN A 221 9.348 9.764 28.817 1.00 36.78 C +ANISOU 1765 CA ASN A 221 6466 4176 3331 548 8 -179 C +ATOM 1766 C ASN A 221 8.866 10.744 27.761 1.00 37.07 C +ANISOU 1766 C ASN A 221 6491 4267 3325 535 13 -186 C +ATOM 1767 O ASN A 221 8.272 10.327 26.773 1.00 37.88 O +ANISOU 1767 O ASN A 221 6645 4351 3396 516 -21 -217 O +ATOM 1768 CB ASN A 221 10.466 8.890 28.251 1.00 37.41 C +ANISOU 1768 CB ASN A 221 6583 4215 3416 618 23 -227 C +ATOM 1769 CG ASN A 221 11.752 9.653 28.077 1.00 37.38 C +ANISOU 1769 CG ASN A 221 6522 4263 3417 674 82 -235 C +ATOM 1770 OD1 ASN A 221 11.789 10.624 27.339 1.00 37.57 O +ANISOU 1770 OD1 ASN A 221 6532 4349 3392 663 122 -238 O +ATOM 1771 ND2 ASN A 221 12.810 9.242 28.790 1.00 37.43 N +ANISOU 1771 ND2 ASN A 221 6495 4238 3488 727 78 -231 N +ATOM 1772 N LEU A 222 9.123 12.033 27.973 1.00 36.63 N +ANISOU 1772 N LEU A 222 6381 4268 3267 538 42 -155 N +ATOM 1773 CA LEU A 222 8.640 13.079 27.072 1.00 37.07 C +ANISOU 1773 CA LEU A 222 6436 4361 3289 522 27 -146 C +ATOM 1774 C LEU A 222 9.356 13.090 25.722 1.00 37.95 C +ANISOU 1774 C LEU A 222 6614 4485 3318 540 51 -177 C +ATOM 1775 O LEU A 222 8.901 13.755 24.789 1.00 40.00 O +ANISOU 1775 O LEU A 222 6914 4760 3525 513 16 -167 O +ATOM 1776 CB LEU A 222 8.745 14.461 27.752 1.00 35.97 C +ANISOU 1776 CB LEU A 222 6231 4260 3174 519 51 -104 C +ATOM 1777 CG LEU A 222 7.880 14.621 28.995 1.00 35.12 C +ANISOU 1777 CG LEU A 222 6068 4142 3134 487 47 -88 C +ATOM 1778 CD1 LEU A 222 8.250 15.863 29.783 1.00 34.74 C +ANISOU 1778 CD1 LEU A 222 5974 4122 3102 488 86 -62 C +ATOM 1779 CD2 LEU A 222 6.422 14.697 28.618 1.00 35.48 C +ANISOU 1779 CD2 LEU A 222 6086 4170 3221 454 -7 -95 C +ATOM 1780 N GLY A 223 10.460 12.354 25.617 1.00 38.65 N +ANISOU 1780 N GLY A 223 6720 4564 3401 581 108 -218 N +ATOM 1781 CA GLY A 223 11.161 12.150 24.354 1.00 39.78 C +ANISOU 1781 CA GLY A 223 6931 4715 3466 592 163 -272 C +ATOM 1782 C GLY A 223 10.541 11.113 23.432 1.00 41.43 C +ANISOU 1782 C GLY A 223 7243 4875 3622 573 125 -325 C +ATOM 1783 O GLY A 223 11.262 10.440 22.680 1.00 42.69 O +ANISOU 1783 O GLY A 223 7461 5017 3739 595 189 -397 O +ATOM 1784 N PHE A 224 9.212 11.018 23.439 1.00 41.86 N +ANISOU 1784 N PHE A 224 7316 4907 3682 526 25 -299 N +ATOM 1785 CA PHE A 224 8.484 10.068 22.609 1.00 44.10 C +ANISOU 1785 CA PHE A 224 7697 5139 3918 492 -37 -344 C +ATOM 1786 C PHE A 224 8.967 9.987 21.142 1.00 45.77 C +ANISOU 1786 C PHE A 224 8038 5354 3997 475 1 -403 C +ATOM 1787 O PHE A 224 9.156 8.893 20.634 1.00 45.80 O +ANISOU 1787 O PHE A 224 8124 5308 3969 482 20 -478 O +ATOM 1788 CB PHE A 224 6.996 10.419 22.650 1.00 45.81 C +ANISOU 1788 CB PHE A 224 7890 5349 4164 433 -157 -299 C +ATOM 1789 CG PHE A 224 6.107 9.465 21.884 1.00 48.47 C +ANISOU 1789 CG PHE A 224 8314 5631 4468 383 -249 -338 C +ATOM 1790 CD1 PHE A 224 5.880 8.190 22.361 1.00 49.45 C +ANISOU 1790 CD1 PHE A 224 8447 5694 4645 378 -257 -372 C +ATOM 1791 CD2 PHE A 224 5.472 9.859 20.716 1.00 50.35 C +ANISOU 1791 CD2 PHE A 224 8636 5869 4623 331 -343 -334 C +ATOM 1792 CE1 PHE A 224 5.035 7.323 21.690 1.00 51.44 C +ANISOU 1792 CE1 PHE A 224 8779 5889 4873 320 -348 -408 C +ATOM 1793 CE2 PHE A 224 4.628 9.008 20.033 1.00 52.42 C +ANISOU 1793 CE2 PHE A 224 8980 6078 4856 274 -446 -369 C +ATOM 1794 CZ PHE A 224 4.413 7.731 20.523 1.00 53.26 C +ANISOU 1794 CZ PHE A 224 9085 6127 5022 268 -444 -410 C +ATOM 1795 N THR A 225 9.192 11.128 20.482 1.00 46.33 N +ANISOU 1795 N THR A 225 8141 5477 3984 447 19 -373 N +ATOM 1796 CA THR A 225 9.486 11.148 19.046 1.00 48.39 C +ANISOU 1796 CA THR A 225 8557 5742 4088 401 50 -419 C +ATOM 1797 C THR A 225 10.911 10.707 18.667 1.00 49.96 C +ANISOU 1797 C THR A 225 8781 5953 4246 437 223 -508 C +ATOM 1798 O THR A 225 11.199 10.552 17.484 1.00 51.84 O +ANISOU 1798 O THR A 225 9161 6189 4344 391 280 -569 O +ATOM 1799 CB THR A 225 9.205 12.541 18.392 1.00 48.87 C +ANISOU 1799 CB THR A 225 8673 5841 4056 340 -1 -347 C +ATOM 1800 OG1 THR A 225 10.083 13.544 18.921 1.00 46.94 O +ANISOU 1800 OG1 THR A 225 8339 5648 3845 365 92 -307 O +ATOM 1801 CG2 THR A 225 7.759 12.973 18.600 1.00 48.50 C +ANISOU 1801 CG2 THR A 225 8592 5768 4066 312 -182 -274 C +ATOM 1802 N ASP A 226 11.796 10.535 19.653 1.00 51.40 N +ANISOU 1802 N ASP A 226 8829 6145 4554 514 306 -518 N +ATOM 1803 CA ASP A 226 13.136 9.959 19.442 1.00 53.21 C +ANISOU 1803 CA ASP A 226 9038 6372 4805 569 460 -614 C +ATOM 1804 C ASP A 226 13.154 8.446 19.709 1.00 51.67 C +ANISOU 1804 C ASP A 226 8849 6091 4691 631 449 -691 C +ATOM 1805 O ASP A 226 14.198 7.814 19.620 1.00 52.92 O +ANISOU 1805 O ASP A 226 8975 6226 4906 696 561 -781 O +ATOM 1806 CB ASP A 226 14.177 10.633 20.356 1.00 55.55 C +ANISOU 1806 CB ASP A 226 9173 6718 5212 620 533 -581 C +ATOM 1807 CG ASP A 226 14.243 12.173 20.173 1.00 59.79 C +ANISOU 1807 CG ASP A 226 9704 7330 5682 557 547 -504 C +ATOM 1808 OD1 ASP A 226 14.406 12.667 19.009 1.00 61.02 O +ANISOU 1808 OD1 ASP A 226 9974 7515 5694 487 612 -523 O +ATOM 1809 OD2 ASP A 226 14.143 12.899 21.221 1.00 61.83 O +ANISOU 1809 OD2 ASP A 226 9857 7610 6026 571 493 -423 O +ATOM 1810 N ILE A 227 12.011 7.866 20.043 1.00 49.76 N +ANISOU 1810 N ILE A 227 8642 5794 4469 610 315 -659 N +ATOM 1811 CA ILE A 227 11.945 6.445 20.324 1.00 50.60 C +ANISOU 1811 CA ILE A 227 8771 5804 4649 655 288 -720 C +ATOM 1812 C ILE A 227 11.641 5.669 19.059 1.00 51.35 C +ANISOU 1812 C ILE A 227 9035 5848 4627 614 297 -817 C +ATOM 1813 O ILE A 227 10.642 5.937 18.398 1.00 50.60 O +ANISOU 1813 O ILE A 227 9040 5762 4422 526 208 -790 O +ATOM 1814 CB ILE A 227 10.874 6.139 21.395 1.00 49.78 C +ANISOU 1814 CB ILE A 227 8624 5662 4628 635 151 -639 C +ATOM 1815 CG1 ILE A 227 11.254 6.803 22.718 1.00 48.52 C +ANISOU 1815 CG1 ILE A 227 8320 5542 4571 671 152 -556 C +ATOM 1816 CG2 ILE A 227 10.733 4.636 21.575 1.00 50.85 C +ANISOU 1816 CG2 ILE A 227 8816 5682 4822 661 113 -696 C +ATOM 1817 CD1 ILE A 227 10.208 6.659 23.793 1.00 48.18 C +ANISOU 1817 CD1 ILE A 227 8240 5474 4590 632 48 -479 C +ATOM 1818 N LEU A 228 12.487 4.692 18.749 1.00 53.16 N +ANISOU 1818 N LEU A 228 9295 6013 4889 678 395 -933 N +ATOM 1819 CA LEU A 228 12.304 3.829 17.577 1.00 55.52 C +ANISOU 1819 CA LEU A 228 9768 6247 5077 644 422 -1050 C +ATOM 1820 C LEU A 228 11.319 2.713 17.867 1.00 55.23 C +ANISOU 1820 C LEU A 228 9797 6104 5082 625 282 -1050 C +ATOM 1821 O LEU A 228 11.664 1.742 18.527 1.00 54.85 O +ANISOU 1821 O LEU A 228 9708 5966 5165 702 279 -1084 O +ATOM 1822 CB LEU A 228 13.646 3.215 17.144 1.00 58.06 C +ANISOU 1822 CB LEU A 228 10085 6533 5439 729 603 -1195 C +ATOM 1823 CG LEU A 228 14.836 4.160 16.936 1.00 58.97 C +ANISOU 1823 CG LEU A 228 10106 6747 5552 754 774 -1216 C +ATOM 1824 CD1 LEU A 228 16.047 3.343 16.477 1.00 60.94 C +ANISOU 1824 CD1 LEU A 228 10339 6942 5872 841 957 -1386 C +ATOM 1825 CD2 LEU A 228 14.484 5.253 15.937 1.00 59.04 C +ANISOU 1825 CD2 LEU A 228 10234 6847 5348 629 801 -1182 C +ATOM 1826 N LEU A 229 10.100 2.835 17.360 1.00 56.03 N +ANISOU 1826 N LEU A 229 10001 6209 5079 519 157 -1012 N +ATOM 1827 CA LEU A 229 9.068 1.889 17.742 1.00 58.01 C +ANISOU 1827 CA LEU A 229 10287 6369 5385 482 17 -996 C +ATOM 1828 C LEU A 229 8.254 1.317 16.589 1.00 59.84 C +ANISOU 1828 C LEU A 229 10708 6546 5480 385 -61 -1061 C +ATOM 1829 O LEU A 229 7.168 0.810 16.803 1.00 59.12 O +ANISOU 1829 O LEU A 229 10639 6403 5420 320 -203 -1027 O +ATOM 1830 CB LEU A 229 8.163 2.523 18.811 1.00 58.18 C +ANISOU 1830 CB LEU A 229 10175 6436 5492 447 -97 -856 C +ATOM 1831 CG LEU A 229 7.721 3.964 18.569 1.00 58.56 C +ANISOU 1831 CG LEU A 229 10180 6596 5474 395 -132 -771 C +ATOM 1832 CD1 LEU A 229 6.843 4.028 17.327 1.00 59.87 C +ANISOU 1832 CD1 LEU A 229 10494 6756 5498 293 -233 -792 C +ATOM 1833 CD2 LEU A 229 7.018 4.543 19.793 1.00 57.36 C +ANISOU 1833 CD2 LEU A 229 9871 6480 5440 386 -205 -657 C +ATOM 1834 N GLU A 230 8.811 1.345 15.382 1.00 62.51 N +ANISOU 1834 N GLU A 230 11190 6892 5668 367 36 -1163 N +ATOM 1835 CA GLU A 230 8.149 0.791 14.205 1.00 64.50 C +ANISOU 1835 CA GLU A 230 11657 7088 5762 267 -34 -1239 C +ATOM 1836 C GLU A 230 8.201 -0.737 14.218 1.00 64.07 C +ANISOU 1836 C GLU A 230 11685 6889 5766 297 -31 -1351 C +ATOM 1837 O GLU A 230 7.211 -1.386 13.892 1.00 65.16 O +ANISOU 1837 O GLU A 230 11935 6956 5866 209 -173 -1362 O +ATOM 1838 CB GLU A 230 8.805 1.352 12.935 1.00 69.05 C +ANISOU 1838 CB GLU A 230 12384 7718 6134 224 91 -1315 C +ATOM 1839 CG GLU A 230 7.994 1.161 11.661 1.00 73.69 C +ANISOU 1839 CG GLU A 230 13214 8272 6509 86 -16 -1357 C +ATOM 1840 CD GLU A 230 8.693 1.720 10.417 1.00 77.55 C +ANISOU 1840 CD GLU A 230 13883 8814 6768 26 124 -1432 C +ATOM 1841 OE1 GLU A 230 9.886 1.396 10.228 1.00 81.99 O +ANISOU 1841 OE1 GLU A 230 14451 9368 7330 95 352 -1556 O +ATOM 1842 OE2 GLU A 230 8.055 2.462 9.618 1.00 78.53 O +ANISOU 1842 OE2 GLU A 230 14146 8979 6714 -95 7 -1369 O +ATOM 1843 N ARG A 231 9.342 -1.310 14.607 1.00 62.33 N +ANISOU 1843 N ARG A 231 11408 6619 5656 421 116 -1434 N +ATOM 1844 CA ARG A 231 9.484 -2.753 14.679 1.00 62.35 C +ANISOU 1844 CA ARG A 231 11485 6465 5739 469 118 -1542 C +ATOM 1845 C ARG A 231 8.571 -3.412 15.713 1.00 60.89 C +ANISOU 1845 C ARG A 231 11244 6200 5691 447 -51 -1449 C +ATOM 1846 O ARG A 231 8.073 -4.515 15.491 1.00 62.99 O +ANISOU 1846 O ARG A 231 11635 6338 5960 408 -126 -1512 O +ATOM 1847 CB ARG A 231 10.937 -3.123 14.957 1.00 63.44 C +ANISOU 1847 CB ARG A 231 11538 6562 6003 623 299 -1640 C +ATOM 1848 CG ARG A 231 11.838 -3.025 13.736 1.00 65.99 C +ANISOU 1848 CG ARG A 231 11969 6907 6196 634 500 -1801 C +ATOM 1849 CD ARG A 231 13.306 -3.141 14.113 1.00 67.27 C +ANISOU 1849 CD ARG A 231 11979 7057 6522 792 685 -1884 C +ATOM 1850 NE ARG A 231 14.091 -3.803 13.073 1.00 70.98 N +ANISOU 1850 NE ARG A 231 12571 7458 6939 827 875 -2098 N +ATOM 1851 CZ ARG A 231 14.140 -5.125 12.859 1.00 73.30 C +ANISOU 1851 CZ ARG A 231 12971 7583 7296 879 878 -2234 C +ATOM 1852 NH1 ARG A 231 13.431 -5.973 13.601 1.00 72.24 N +ANISOU 1852 NH1 ARG A 231 12848 7326 7273 891 690 -2171 N +ATOM 1853 NH2 ARG A 231 14.900 -5.609 11.870 1.00 76.48 N +ANISOU 1853 NH2 ARG A 231 13479 7933 7644 910 1082 -2445 N +ATOM 1854 N VAL A 232 8.353 -2.751 16.839 1.00 58.38 N +ANISOU 1854 N VAL A 232 10749 5952 5478 462 -103 -1306 N +ATOM 1855 CA VAL A 232 7.434 -3.252 17.862 1.00 57.35 C +ANISOU 1855 CA VAL A 232 10565 5763 5461 416 -245 -1210 C +ATOM 1856 C VAL A 232 5.975 -3.140 17.418 1.00 57.23 C +ANISOU 1856 C VAL A 232 10611 5766 5365 265 -397 -1165 C +ATOM 1857 O VAL A 232 5.185 -4.030 17.700 1.00 56.73 O +ANISOU 1857 O VAL A 232 10593 5606 5355 197 -503 -1158 O +ATOM 1858 CB VAL A 232 7.642 -2.503 19.211 1.00 56.20 C +ANISOU 1858 CB VAL A 232 10223 5695 5436 465 -239 -1078 C +ATOM 1859 CG1 VAL A 232 6.522 -2.784 20.197 1.00 55.23 C +ANISOU 1859 CG1 VAL A 232 10050 5541 5392 380 -367 -972 C +ATOM 1860 CG2 VAL A 232 8.962 -2.918 19.824 1.00 56.39 C +ANISOU 1860 CG2 VAL A 232 10186 5660 5578 608 -143 -1115 C +ATOM 1861 N MET A 233 5.614 -2.051 16.746 1.00 58.51 N +ANISOU 1861 N MET A 233 10772 6045 5413 207 -419 -1130 N +ATOM 1862 CA MET A 233 4.233 -1.857 16.282 1.00 60.42 C +ANISOU 1862 CA MET A 233 11053 6304 5599 70 -588 -1084 C +ATOM 1863 C MET A 233 3.821 -2.870 15.225 1.00 60.43 C +ANISOU 1863 C MET A 233 11266 6198 5495 -11 -661 -1194 C +ATOM 1864 O MET A 233 2.674 -3.313 15.225 1.00 59.61 O +ANISOU 1864 O MET A 233 11181 6048 5421 -118 -817 -1167 O +ATOM 1865 CB MET A 233 4.007 -0.445 15.737 1.00 63.37 C +ANISOU 1865 CB MET A 233 11394 6807 5875 35 -616 -1021 C +ATOM 1866 CG MET A 233 3.706 0.590 16.812 1.00 64.84 C +ANISOU 1866 CG MET A 233 11364 7088 6183 59 -631 -890 C +ATOM 1867 SD MET A 233 3.151 2.205 16.203 1.00 71.77 S +ANISOU 1867 SD MET A 233 12204 8085 6980 8 -717 -804 S +ATOM 1868 CE MET A 233 4.005 2.385 14.627 1.00 72.42 C +ANISOU 1868 CE MET A 233 12519 8175 6820 -5 -644 -896 C +ATOM 1869 N HIS A 234 4.759 -3.237 14.355 1.00 59.91 N +ANISOU 1869 N HIS A 234 11354 6091 5315 34 -540 -1323 N +ATOM 1870 CA HIS A 234 4.523 -4.230 13.303 1.00 61.41 C +ANISOU 1870 CA HIS A 234 11776 6170 5387 -37 -582 -1452 C +ATOM 1871 C HIS A 234 3.924 -5.511 13.861 1.00 59.97 C +ANISOU 1871 C HIS A 234 11614 5844 5327 -68 -679 -1467 C +ATOM 1872 O HIS A 234 3.065 -6.127 13.228 1.00 60.74 O +ANISOU 1872 O HIS A 234 11852 5868 5357 -187 -813 -1509 O +ATOM 1873 CB HIS A 234 5.839 -4.551 12.581 1.00 63.86 C +ANISOU 1873 CB HIS A 234 12212 6444 5605 49 -379 -1608 C +ATOM 1874 CG HIS A 234 5.672 -5.339 11.318 1.00 67.68 C +ANISOU 1874 CG HIS A 234 12965 6832 5918 -34 -394 -1756 C +ATOM 1875 ND1 HIS A 234 5.346 -4.751 10.113 1.00 68.83 N +ANISOU 1875 ND1 HIS A 234 13281 7037 5833 -150 -436 -1778 N +ATOM 1876 CD2 HIS A 234 5.799 -6.666 11.070 1.00 70.03 C +ANISOU 1876 CD2 HIS A 234 13406 6969 6232 -24 -376 -1892 C +ATOM 1877 CE1 HIS A 234 5.268 -5.683 9.179 1.00 71.29 C +ANISOU 1877 CE1 HIS A 234 13836 7236 6014 -215 -440 -1925 C +ATOM 1878 NE2 HIS A 234 5.539 -6.852 9.733 1.00 72.04 N +ANISOU 1878 NE2 HIS A 234 13914 7195 6262 -137 -399 -2001 N +ATOM 1879 N GLY A 235 4.368 -5.902 15.057 1.00 56.97 N +ANISOU 1879 N GLY A 235 11102 5419 5122 26 -623 -1427 N +ATOM 1880 CA GLY A 235 3.883 -7.120 15.686 1.00 56.14 C +ANISOU 1880 CA GLY A 235 11026 5167 5135 -7 -708 -1428 C +ATOM 1881 C GLY A 235 2.484 -7.018 16.265 1.00 54.24 C +ANISOU 1881 C GLY A 235 10693 4952 4963 -142 -873 -1308 C +ATOM 1882 O GLY A 235 1.852 -8.034 16.561 1.00 54.59 O +ANISOU 1882 O GLY A 235 10792 4874 5074 -220 -963 -1313 O +ATOM 1883 N GLY A 236 1.999 -5.799 16.454 1.00 51.88 N +ANISOU 1883 N GLY A 236 10246 4803 4661 -173 -906 -1202 N +ATOM 1884 CA GLY A 236 0.644 -5.580 16.960 1.00 51.23 C +ANISOU 1884 CA GLY A 236 10044 4758 4663 -299 -1047 -1100 C +ATOM 1885 C GLY A 236 0.538 -5.047 18.385 1.00 49.39 C +ANISOU 1885 C GLY A 236 9597 4593 4574 -270 -1002 -979 C +ATOM 1886 O GLY A 236 -0.541 -5.042 18.947 1.00 49.46 O +ANISOU 1886 O GLY A 236 9501 4615 4676 -374 -1087 -910 O +ATOM 1887 N ALA A 237 1.645 -4.608 18.974 1.00 48.04 N +ANISOU 1887 N ALA A 237 9363 4464 4424 -137 -866 -958 N +ATOM 1888 CA ALA A 237 1.662 -4.131 20.366 1.00 46.29 C +ANISOU 1888 CA ALA A 237 8969 4298 4319 -111 -817 -850 C +ATOM 1889 C ALA A 237 1.027 -2.767 20.489 1.00 44.46 C +ANISOU 1889 C ALA A 237 8577 4216 4098 -142 -839 -770 C +ATOM 1890 O ALA A 237 1.223 -1.937 19.628 1.00 44.18 O +ANISOU 1890 O ALA A 237 8555 4257 3972 -114 -840 -787 O +ATOM 1891 CB ALA A 237 3.101 -4.051 20.872 1.00 45.85 C +ANISOU 1891 CB ALA A 237 8901 4238 4281 40 -686 -858 C +ATOM 1892 N ASN A 238 0.287 -2.539 21.569 1.00 43.59 N +ANISOU 1892 N ASN A 238 8324 4138 4098 -203 -850 -685 N +ATOM 1893 CA ASN A 238 -0.175 -1.199 21.918 1.00 42.54 C +ANISOU 1893 CA ASN A 238 8018 4138 4006 -206 -842 -614 C +ATOM 1894 C ASN A 238 0.990 -0.416 22.482 1.00 40.17 C +ANISOU 1894 C ASN A 238 7667 3904 3691 -81 -717 -582 C +ATOM 1895 O ASN A 238 1.838 -0.967 23.159 1.00 39.02 O +ANISOU 1895 O ASN A 238 7559 3703 3561 -21 -646 -582 O +ATOM 1896 CB ASN A 238 -1.335 -1.229 22.923 1.00 43.42 C +ANISOU 1896 CB ASN A 238 7988 4261 4247 -317 -865 -553 C +ATOM 1897 CG ASN A 238 -2.575 -1.868 22.349 1.00 45.85 C +ANISOU 1897 CG ASN A 238 8309 4518 4594 -454 -999 -581 C +ATOM 1898 OD1 ASN A 238 -2.632 -3.052 22.175 1.00 48.14 O +ANISOU 1898 OD1 ASN A 238 8725 4695 4870 -509 -1037 -622 O +ATOM 1899 ND2 ASN A 238 -3.574 -1.069 22.042 1.00 48.19 N +ANISOU 1899 ND2 ASN A 238 8469 4888 4952 -509 -1081 -561 N +ATOM 1900 N ILE A 239 1.052 0.871 22.152 1.00 39.13 N +ANISOU 1900 N ILE A 239 7455 3881 3529 -42 -706 -556 N +ATOM 1901 CA ILE A 239 2.064 1.749 22.715 1.00 37.58 C +ANISOU 1901 CA ILE A 239 7194 3755 3328 59 -595 -520 C +ATOM 1902 C ILE A 239 1.428 3.051 23.129 1.00 35.98 C +ANISOU 1902 C ILE A 239 6836 3654 3181 42 -602 -454 C +ATOM 1903 O ILE A 239 0.707 3.629 22.371 1.00 35.99 O +ANISOU 1903 O ILE A 239 6812 3689 3170 5 -689 -452 O +ATOM 1904 CB ILE A 239 3.209 1.963 21.717 1.00 38.00 C +ANISOU 1904 CB ILE A 239 7348 3821 3266 146 -542 -578 C +ATOM 1905 CG1 ILE A 239 4.056 0.701 21.641 1.00 39.25 C +ANISOU 1905 CG1 ILE A 239 7626 3872 3412 195 -496 -650 C +ATOM 1906 CG2 ILE A 239 4.140 3.077 22.150 1.00 36.98 C +ANISOU 1906 CG2 ILE A 239 7133 3780 3135 233 -442 -538 C +ATOM 1907 CD1 ILE A 239 4.801 0.574 20.325 1.00 40.74 C +ANISOU 1907 CD1 ILE A 239 7948 4049 3481 237 -455 -746 C +ATOM 1908 N THR A 240 1.693 3.482 24.352 1.00 34.86 N +ANISOU 1908 N THR A 240 6595 3547 3100 68 -519 -403 N +ATOM 1909 CA THR A 240 1.220 4.756 24.853 1.00 33.79 C +ANISOU 1909 CA THR A 240 6314 3499 3023 66 -501 -353 C +ATOM 1910 C THR A 240 2.424 5.634 25.114 1.00 32.45 C +ANISOU 1910 C THR A 240 6134 3386 2809 165 -411 -331 C +ATOM 1911 O THR A 240 3.435 5.184 25.643 1.00 31.19 O +ANISOU 1911 O THR A 240 6020 3200 2631 216 -345 -333 O +ATOM 1912 CB THR A 240 0.436 4.607 26.152 1.00 34.02 C +ANISOU 1912 CB THR A 240 6242 3526 3158 -7 -463 -319 C +ATOM 1913 OG1 THR A 240 -0.738 3.838 25.919 1.00 35.40 O +ANISOU 1913 OG1 THR A 240 6405 3654 3391 -113 -541 -340 O +ATOM 1914 CG2 THR A 240 0.010 5.973 26.675 1.00 33.70 C +ANISOU 1914 CG2 THR A 240 6050 3570 3184 2 -425 -286 C +ATOM 1915 N GLY A 241 2.292 6.901 24.737 1.00 32.28 N +ANISOU 1915 N GLY A 241 6047 3434 2782 188 -424 -309 N +ATOM 1916 CA GLY A 241 3.384 7.842 24.799 1.00 32.09 C +ANISOU 1916 CA GLY A 241 6016 3464 2711 267 -349 -289 C +ATOM 1917 C GLY A 241 2.879 9.212 25.174 1.00 32.21 C +ANISOU 1917 C GLY A 241 5912 3540 2784 268 -351 -245 C +ATOM 1918 O GLY A 241 1.671 9.432 25.191 1.00 31.77 O +ANISOU 1918 O GLY A 241 5777 3483 2811 217 -418 -239 O +ATOM 1919 N PHE A 242 3.818 10.103 25.500 1.00 32.84 N +ANISOU 1919 N PHE A 242 5974 3666 2838 326 -277 -221 N +ATOM 1920 CA PHE A 242 3.508 11.461 25.969 1.00 33.66 C +ANISOU 1920 CA PHE A 242 5974 3815 2998 337 -265 -184 C +ATOM 1921 C PHE A 242 4.351 12.520 25.266 1.00 33.70 C +ANISOU 1921 C PHE A 242 6017 3857 2929 384 -254 -164 C +ATOM 1922 O PHE A 242 5.555 12.331 25.076 1.00 33.79 O +ANISOU 1922 O PHE A 242 6092 3880 2865 419 -189 -176 O +ATOM 1923 CB PHE A 242 3.759 11.550 27.451 1.00 33.56 C +ANISOU 1923 CB PHE A 242 5900 3814 3036 337 -173 -168 C +ATOM 1924 CG PHE A 242 3.016 10.526 28.247 1.00 35.10 C +ANISOU 1924 CG PHE A 242 6077 3970 3285 272 -164 -180 C +ATOM 1925 CD1 PHE A 242 3.568 9.264 28.494 1.00 36.18 C +ANISOU 1925 CD1 PHE A 242 6302 4058 3383 264 -152 -189 C +ATOM 1926 CD2 PHE A 242 1.773 10.800 28.750 1.00 36.32 C +ANISOU 1926 CD2 PHE A 242 6129 4131 3541 214 -164 -184 C +ATOM 1927 CE1 PHE A 242 2.880 8.298 29.220 1.00 36.42 C +ANISOU 1927 CE1 PHE A 242 6340 4043 3454 187 -148 -191 C +ATOM 1928 CE2 PHE A 242 1.090 9.852 29.505 1.00 37.05 C +ANISOU 1928 CE2 PHE A 242 6210 4190 3677 133 -137 -196 C +ATOM 1929 CZ PHE A 242 1.632 8.591 29.717 1.00 36.83 C +ANISOU 1929 CZ PHE A 242 6293 4110 3590 112 -134 -193 C +ATOM 1930 N GLN A 243 3.721 13.618 24.871 1.00 34.67 N +ANISOU 1930 N GLN A 243 6098 3992 3083 381 -318 -137 N +ATOM 1931 CA GLN A 243 4.454 14.765 24.329 1.00 35.20 C +ANISOU 1931 CA GLN A 243 6204 4085 3082 410 -308 -106 C +ATOM 1932 C GLN A 243 3.942 16.080 24.869 1.00 34.44 C +ANISOU 1932 C GLN A 243 6009 3995 3081 425 -325 -71 C +ATOM 1933 O GLN A 243 2.778 16.199 25.257 1.00 33.62 O +ANISOU 1933 O GLN A 243 5805 3870 3096 413 -376 -77 O +ATOM 1934 CB GLN A 243 4.372 14.829 22.809 1.00 37.16 C +ANISOU 1934 CB GLN A 243 6573 4319 3226 386 -400 -101 C +ATOM 1935 CG GLN A 243 5.112 13.734 22.076 1.00 38.60 C +ANISOU 1935 CG GLN A 243 6881 4495 3288 375 -359 -150 C +ATOM 1936 CD GLN A 243 4.970 13.908 20.585 1.00 40.72 C +ANISOU 1936 CD GLN A 243 7293 4748 3428 331 -446 -147 C +ATOM 1937 OE1 GLN A 243 4.299 13.114 19.889 1.00 43.22 O +ANISOU 1937 OE1 GLN A 243 7683 5028 3710 289 -539 -175 O +ATOM 1938 NE2 GLN A 243 5.583 14.958 20.084 1.00 41.22 N +ANISOU 1938 NE2 GLN A 243 7413 4836 3411 328 -423 -110 N +ATOM 1939 N ILE A 244 4.834 17.061 24.859 1.00 33.94 N +ANISOU 1939 N ILE A 244 5969 3954 2969 449 -276 -42 N +ATOM 1940 CA ILE A 244 4.484 18.424 25.250 1.00 34.70 C +ANISOU 1940 CA ILE A 244 5997 4042 3145 468 -295 -11 C +ATOM 1941 C ILE A 244 4.701 19.421 24.127 1.00 35.44 C +ANISOU 1941 C ILE A 244 6178 4119 3167 465 -371 35 C +ATOM 1942 O ILE A 244 4.414 20.583 24.293 1.00 35.07 O +ANISOU 1942 O ILE A 244 6092 4047 3186 483 -408 66 O +ATOM 1943 CB ILE A 244 5.264 18.905 26.503 1.00 33.40 C +ANISOU 1943 CB ILE A 244 5782 3905 3004 487 -174 -13 C +ATOM 1944 CG1 ILE A 244 6.768 18.686 26.342 1.00 32.93 C +ANISOU 1944 CG1 ILE A 244 5795 3881 2833 490 -95 -8 C +ATOM 1945 CG2 ILE A 244 4.818 18.138 27.732 1.00 33.42 C +ANISOU 1945 CG2 ILE A 244 5708 3909 3078 475 -114 -48 C +ATOM 1946 CD1 ILE A 244 7.586 19.400 27.388 1.00 32.59 C +ANISOU 1946 CD1 ILE A 244 5712 3861 2809 501 -13 1 C +ATOM 1947 N VAL A 245 5.247 18.982 23.011 1.00 37.73 N +ANISOU 1947 N VAL A 245 6598 4417 3318 436 -387 39 N +ATOM 1948 CA VAL A 245 5.377 19.827 21.819 1.00 40.83 C +ANISOU 1948 CA VAL A 245 7111 4788 3611 407 -469 89 C +ATOM 1949 C VAL A 245 4.332 19.380 20.819 1.00 44.09 C +ANISOU 1949 C VAL A 245 7588 5158 4005 375 -631 95 C +ATOM 1950 O VAL A 245 4.315 18.218 20.428 1.00 46.64 O +ANISOU 1950 O VAL A 245 7964 5489 4266 350 -625 51 O +ATOM 1951 CB VAL A 245 6.757 19.685 21.156 1.00 40.54 C +ANISOU 1951 CB VAL A 245 7201 4793 3409 374 -358 82 C +ATOM 1952 CG1 VAL A 245 6.876 20.655 19.997 1.00 41.92 C +ANISOU 1952 CG1 VAL A 245 7520 4941 3465 321 -432 143 C +ATOM 1953 CG2 VAL A 245 7.857 19.929 22.181 1.00 39.87 C +ANISOU 1953 CG2 VAL A 245 7035 4753 3358 403 -208 69 C +ATOM 1954 N ASN A 246 3.448 20.288 20.426 1.00 47.31 N +ANISOU 1954 N ASN A 246 7989 5509 4476 377 -789 147 N +ATOM 1955 CA ASN A 246 2.421 20.000 19.436 1.00 50.71 C +ANISOU 1955 CA ASN A 246 8480 5888 4898 342 -984 164 C +ATOM 1956 C ASN A 246 2.891 20.551 18.103 1.00 54.43 C +ANISOU 1956 C ASN A 246 9168 6334 5176 281 -1063 223 C +ATOM 1957 O ASN A 246 3.188 21.737 17.979 1.00 55.07 O +ANISOU 1957 O ASN A 246 9292 6390 5243 283 -1086 285 O +ATOM 1958 CB ASN A 246 1.109 20.648 19.858 1.00 52.29 C +ANISOU 1958 CB ASN A 246 8520 6029 5317 387 -1128 182 C +ATOM 1959 CG ASN A 246 0.020 20.517 18.820 1.00 55.01 C +ANISOU 1959 CG ASN A 246 8911 6309 5680 355 -1370 211 C +ATOM 1960 OD1 ASN A 246 -0.034 19.553 18.052 1.00 56.52 O +ANISOU 1960 OD1 ASN A 246 9216 6508 5752 295 -1420 193 O +ATOM 1961 ND2 ASN A 246 -0.866 21.507 18.788 1.00 57.31 N +ANISOU 1961 ND2 ASN A 246 9115 6528 6132 395 -1535 255 N +ATOM 1962 N ASN A 247 2.981 19.686 17.094 1.00 58.99 N +ANISOU 1962 N ASN A 247 9903 6915 5592 215 -1099 202 N +ATOM 1963 CA ASN A 247 3.584 20.077 15.823 1.00 62.75 C +ANISOU 1963 CA ASN A 247 10622 7379 5841 133 -1129 245 C +ATOM 1964 C ASN A 247 2.669 20.910 14.958 1.00 64.25 C +ANISOU 1964 C ASN A 247 10910 7482 6020 97 -1391 335 C +ATOM 1965 O ASN A 247 3.140 21.620 14.089 1.00 64.28 O +ANISOU 1965 O ASN A 247 11109 7460 5852 28 -1427 398 O +ATOM 1966 CB ASN A 247 4.078 18.854 15.088 1.00 66.20 C +ANISOU 1966 CB ASN A 247 11206 7847 6098 72 -1049 174 C +ATOM 1967 CG ASN A 247 5.052 18.049 15.926 1.00 67.53 C +ANISOU 1967 CG ASN A 247 11277 8086 6294 119 -806 89 C +ATOM 1968 OD1 ASN A 247 5.576 18.536 16.944 1.00 68.94 O +ANISOU 1968 OD1 ASN A 247 11315 8298 6579 178 -689 94 O +ATOM 1969 ND2 ASN A 247 5.286 16.799 15.523 1.00 71.68 N +ANISOU 1969 ND2 ASN A 247 11879 8623 6731 93 -744 8 N +ATOM 1970 N GLU A 248 1.368 20.845 15.221 1.00 66.60 N +ANISOU 1970 N GLU A 248 11067 7727 6510 139 -1575 342 N +ATOM 1971 CA GLU A 248 0.395 21.670 14.500 1.00 69.29 C +ANISOU 1971 CA GLU A 248 11461 7967 6896 125 -1861 431 C +ATOM 1972 C GLU A 248 0.378 23.115 15.031 1.00 67.43 C +ANISOU 1972 C GLU A 248 11138 7682 6798 191 -1890 496 C +ATOM 1973 O GLU A 248 -0.176 23.994 14.385 1.00 68.06 O +ANISOU 1973 O GLU A 248 11298 7666 6896 181 -2119 584 O +ATOM 1974 CB GLU A 248 -1.016 21.068 14.583 1.00 73.13 C +ANISOU 1974 CB GLU A 248 11798 8413 7574 149 -2055 405 C +ATOM 1975 CG GLU A 248 -1.153 19.623 14.112 1.00 76.73 C +ANISOU 1975 CG GLU A 248 12330 8901 7922 81 -2052 337 C +ATOM 1976 CD GLU A 248 -0.969 19.435 12.606 1.00 81.96 C +ANISOU 1976 CD GLU A 248 13304 9529 8309 -35 -2189 375 C +ATOM 1977 OE1 GLU A 248 -1.703 20.066 11.791 1.00 86.75 O +ANISOU 1977 OE1 GLU A 248 14005 10047 8906 -72 -2467 460 O +ATOM 1978 OE2 GLU A 248 -0.091 18.624 12.236 1.00 83.74 O +ANISOU 1978 OE2 GLU A 248 13684 9809 8324 -94 -2019 315 O +ATOM 1979 N ASN A 249 0.971 23.358 16.204 1.00 63.83 N +ANISOU 1979 N ASN A 249 10530 7281 6440 256 -1674 455 N +ATOM 1980 CA ASN A 249 1.108 24.718 16.756 1.00 62.58 C +ANISOU 1980 CA ASN A 249 10307 7075 6393 312 -1670 504 C +ATOM 1981 C ASN A 249 1.953 25.577 15.812 1.00 62.86 C +ANISOU 1981 C ASN A 249 10594 7078 6212 232 -1695 593 C +ATOM 1982 O ASN A 249 3.122 25.257 15.574 1.00 60.51 O +ANISOU 1982 O ASN A 249 10421 6855 5713 165 -1508 575 O +ATOM 1983 CB ASN A 249 1.761 24.672 18.147 1.00 59.85 C +ANISOU 1983 CB ASN A 249 9793 6804 6140 371 -1416 434 C +ATOM 1984 CG ASN A 249 2.055 26.054 18.733 1.00 59.40 C +ANISOU 1984 CG ASN A 249 9695 6701 6173 417 -1387 473 C +ATOM 1985 OD1 ASN A 249 1.907 27.084 18.077 1.00 60.10 O +ANISOU 1985 OD1 ASN A 249 9892 6698 6243 403 -1542 558 O +ATOM 1986 ND2 ASN A 249 2.552 26.063 19.971 1.00 57.98 N +ANISOU 1986 ND2 ASN A 249 9378 6578 6074 461 -1190 414 N +ATOM 1987 N PRO A 250 1.372 26.679 15.288 1.00 64.77 N +ANISOU 1987 N PRO A 250 10907 7201 6501 235 -1924 690 N +ATOM 1988 CA PRO A 250 2.092 27.482 14.300 1.00 65.91 C +ANISOU 1988 CA PRO A 250 11324 7300 6419 135 -1969 789 C +ATOM 1989 C PRO A 250 3.414 28.072 14.817 1.00 64.39 C +ANISOU 1989 C PRO A 250 11154 7163 6149 113 -1721 785 C +ATOM 1990 O PRO A 250 4.337 28.245 14.032 1.00 64.50 O +ANISOU 1990 O PRO A 250 11390 7197 5920 -1 -1646 827 O +ATOM 1991 CB PRO A 250 1.081 28.577 13.914 1.00 68.22 C +ANISOU 1991 CB PRO A 250 11638 7433 6847 172 -2281 891 C +ATOM 1992 CG PRO A 250 0.103 28.629 15.029 1.00 68.13 C +ANISOU 1992 CG PRO A 250 11312 7397 7177 316 -2314 826 C +ATOM 1993 CD PRO A 250 0.046 27.247 15.601 1.00 66.59 C +ANISOU 1993 CD PRO A 250 10965 7325 7009 331 -2146 709 C +ATOM 1994 N MET A 251 3.516 28.352 16.117 1.00 63.12 N +ANISOU 1994 N MET A 251 10770 7026 6184 210 -1589 731 N +ATOM 1995 CA MET A 251 4.784 28.805 16.709 1.00 61.61 C +ANISOU 1995 CA MET A 251 10577 6896 5934 187 -1356 717 C +ATOM 1996 C MET A 251 5.894 27.751 16.554 1.00 57.49 C +ANISOU 1996 C MET A 251 10107 6506 5228 119 -1127 651 C +ATOM 1997 O MET A 251 7.057 28.084 16.310 1.00 55.59 O +ANISOU 1997 O MET A 251 9975 6307 4840 41 -980 667 O +ATOM 1998 CB MET A 251 4.593 29.159 18.198 1.00 63.16 C +ANISOU 1998 CB MET A 251 10528 7096 6374 300 -1268 657 C +ATOM 1999 CG MET A 251 5.824 29.751 18.888 1.00 64.74 C +ANISOU 1999 CG MET A 251 10718 7340 6536 278 -1066 648 C +ATOM 2000 SD MET A 251 5.630 30.116 20.662 1.00 69.30 S +ANISOU 2000 SD MET A 251 11045 7923 7363 391 -957 568 S +ATOM 2001 CE MET A 251 4.196 31.215 20.640 1.00 69.59 C +ANISOU 2001 CE MET A 251 11026 7791 7622 479 -1202 609 C +ATOM 2002 N VAL A 252 5.537 26.479 16.708 1.00 53.78 N +ANISOU 2002 N VAL A 252 9551 6096 4784 150 -1094 572 N +ATOM 2003 CA VAL A 252 6.508 25.416 16.551 1.00 52.07 C +ANISOU 2003 CA VAL A 252 9376 5985 4422 104 -894 500 C +ATOM 2004 C VAL A 252 6.892 25.319 15.086 1.00 53.51 C +ANISOU 2004 C VAL A 252 9824 6161 4345 -20 -922 537 C +ATOM 2005 O VAL A 252 8.069 25.284 14.753 1.00 52.08 O +ANISOU 2005 O VAL A 252 9738 6040 4009 -94 -739 518 O +ATOM 2006 CB VAL A 252 5.967 24.061 17.058 1.00 49.97 C +ANISOU 2006 CB VAL A 252 8970 5764 4249 164 -871 410 C +ATOM 2007 CG1 VAL A 252 6.915 22.918 16.697 1.00 48.75 C +ANISOU 2007 CG1 VAL A 252 8887 5693 3941 119 -694 335 C +ATOM 2008 CG2 VAL A 252 5.715 24.130 18.553 1.00 47.51 C +ANISOU 2008 CG2 VAL A 252 8421 5469 4161 264 -806 369 C +ATOM 2009 N GLN A 253 5.883 25.297 14.222 1.00 56.81 N +ANISOU 2009 N GLN A 253 10361 6502 4720 -50 -1155 588 N +ATOM 2010 CA GLN A 253 6.077 25.256 12.758 1.00 59.85 C +ANISOU 2010 CA GLN A 253 11042 6863 4835 -187 -1221 633 C +ATOM 2011 C GLN A 253 6.992 26.361 12.242 1.00 60.11 C +ANISOU 2011 C GLN A 253 11256 6876 4705 -290 -1154 712 C +ATOM 2012 O GLN A 253 7.934 26.079 11.526 1.00 60.85 O +ANISOU 2012 O GLN A 253 11518 7026 4574 -403 -990 686 O +ATOM 2013 CB GLN A 253 4.726 25.309 12.021 1.00 62.50 C +ANISOU 2013 CB GLN A 253 11469 7094 5184 -198 -1544 700 C +ATOM 2014 CG GLN A 253 3.911 24.034 12.182 1.00 63.84 C +ANISOU 2014 CG GLN A 253 11523 7287 5444 -148 -1602 617 C +ATOM 2015 CD GLN A 253 2.646 24.015 11.342 1.00 68.59 C +ANISOU 2015 CD GLN A 253 12223 7790 6047 -178 -1929 679 C +ATOM 2016 OE1 GLN A 253 2.041 25.064 11.068 1.00 70.34 O +ANISOU 2016 OE1 GLN A 253 12488 7905 6330 -173 -2158 785 O +ATOM 2017 NE2 GLN A 253 2.227 22.802 10.939 1.00 70.33 N +ANISOU 2017 NE2 GLN A 253 12477 8033 6212 -208 -1969 611 N +ATOM 2018 N GLN A 254 6.724 27.609 12.613 1.00 60.13 N +ANISOU 2018 N GLN A 254 11222 6797 4827 -257 -1269 801 N +ATOM 2019 CA GLN A 254 7.548 28.733 12.151 1.00 61.58 C +ANISOU 2019 CA GLN A 254 11586 6946 4865 -365 -1220 887 C +ATOM 2020 C GLN A 254 8.949 28.701 12.773 1.00 58.55 C +ANISOU 2020 C GLN A 254 11107 6674 4464 -384 -903 819 C +ATOM 2021 O GLN A 254 9.906 29.167 12.156 1.00 59.46 O +ANISOU 2021 O GLN A 254 11393 6806 4390 -516 -779 851 O +ATOM 2022 CB GLN A 254 6.873 30.089 12.399 1.00 64.24 C +ANISOU 2022 CB GLN A 254 11913 7145 5351 -318 -1441 999 C +ATOM 2023 CG GLN A 254 6.906 30.562 13.853 1.00 65.62 C +ANISOU 2023 CG GLN A 254 11811 7327 5795 -185 -1357 957 C +ATOM 2024 CD GLN A 254 6.118 31.858 14.066 1.00 68.55 C +ANISOU 2024 CD GLN A 254 12169 7541 6335 -123 -1586 1050 C +ATOM 2025 OE1 GLN A 254 5.730 32.546 13.094 1.00 69.94 O +ANISOU 2025 OE1 GLN A 254 12564 7596 6414 -193 -1806 1166 O +ATOM 2026 NE2 GLN A 254 5.855 32.185 15.349 1.00 67.38 N +ANISOU 2026 NE2 GLN A 254 11772 7384 6444 7 -1542 996 N +ATOM 2027 N PHE A 255 9.087 28.155 13.978 1.00 54.31 N +ANISOU 2027 N PHE A 255 10305 6210 4120 -264 -776 725 N +ATOM 2028 CA PHE A 255 10.411 27.992 14.545 1.00 52.17 C +ANISOU 2028 CA PHE A 255 9937 6042 3842 -279 -502 656 C +ATOM 2029 C PHE A 255 11.200 26.928 13.763 1.00 52.98 C +ANISOU 2029 C PHE A 255 10140 6237 3754 -361 -320 575 C +ATOM 2030 O PHE A 255 12.379 27.128 13.440 1.00 53.02 O +ANISOU 2030 O PHE A 255 10208 6297 3637 -458 -122 558 O +ATOM 2031 CB PHE A 255 10.340 27.629 16.024 1.00 49.57 C +ANISOU 2031 CB PHE A 255 9324 5758 3752 -139 -435 583 C +ATOM 2032 CG PHE A 255 11.676 27.325 16.617 1.00 47.42 C +ANISOU 2032 CG PHE A 255 8941 5587 3486 -147 -185 511 C +ATOM 2033 CD1 PHE A 255 12.503 28.347 17.046 1.00 47.27 C +ANISOU 2033 CD1 PHE A 255 8895 5569 3493 -186 -100 546 C +ATOM 2034 CD2 PHE A 255 12.135 26.031 16.663 1.00 46.06 C +ANISOU 2034 CD2 PHE A 255 8704 5501 3294 -124 -46 410 C +ATOM 2035 CE1 PHE A 255 13.745 28.055 17.567 1.00 46.91 C +ANISOU 2035 CE1 PHE A 255 8735 5617 3470 -198 110 479 C +ATOM 2036 CE2 PHE A 255 13.383 25.733 17.151 1.00 45.54 C +ANISOU 2036 CE2 PHE A 255 8529 5520 3254 -126 164 343 C +ATOM 2037 CZ PHE A 255 14.190 26.735 17.611 1.00 46.01 C +ANISOU 2037 CZ PHE A 255 8541 5587 3351 -163 240 377 C +ATOM 2038 N ILE A 256 10.540 25.811 13.454 1.00 53.38 N +ANISOU 2038 N ILE A 256 10200 6296 3785 -326 -383 519 N +ATOM 2039 CA ILE A 256 11.168 24.705 12.726 1.00 54.40 C +ANISOU 2039 CA ILE A 256 10426 6496 3748 -389 -219 424 C +ATOM 2040 C ILE A 256 11.657 25.167 11.349 1.00 55.75 C +ANISOU 2040 C ILE A 256 10896 6652 3634 -567 -180 469 C +ATOM 2041 O ILE A 256 12.772 24.857 10.940 1.00 54.60 O +ANISOU 2041 O ILE A 256 10803 6579 3360 -647 62 397 O +ATOM 2042 CB ILE A 256 10.195 23.509 12.577 1.00 55.50 C +ANISOU 2042 CB ILE A 256 10552 6621 3912 -330 -339 367 C +ATOM 2043 CG1 ILE A 256 9.817 22.909 13.960 1.00 54.81 C +ANISOU 2043 CG1 ILE A 256 10179 6557 4086 -176 -335 311 C +ATOM 2044 CG2 ILE A 256 10.787 22.426 11.684 1.00 57.22 C +ANISOU 2044 CG2 ILE A 256 10912 6890 3937 -405 -184 266 C +ATOM 2045 CD1 ILE A 256 10.761 21.859 14.526 1.00 53.78 C +ANISOU 2045 CD1 ILE A 256 9915 6513 4004 -125 -106 191 C +ATOM 2046 N GLN A 257 10.810 25.915 10.651 1.00 57.63 N +ANISOU 2046 N GLN A 257 11326 6789 3781 -630 -421 587 N +ATOM 2047 CA GLN A 257 11.123 26.457 9.332 1.00 60.50 C +ANISOU 2047 CA GLN A 257 12016 7115 3853 -817 -429 657 C +ATOM 2048 C GLN A 257 12.469 27.175 9.291 1.00 60.36 C +ANISOU 2048 C GLN A 257 12033 7151 3750 -923 -180 661 C +ATOM 2049 O GLN A 257 13.271 26.944 8.405 1.00 62.25 O +ANISOU 2049 O GLN A 257 12454 7439 3759 -1068 7 618 O +ATOM 2050 CB GLN A 257 10.001 27.397 8.855 1.00 62.87 C +ANISOU 2050 CB GLN A 257 12481 7275 4132 -845 -770 811 C +ATOM 2051 CG GLN A 257 8.784 26.658 8.286 1.00 64.50 C +ANISOU 2051 CG GLN A 257 12775 7425 4306 -825 -1019 813 C +ATOM 2052 CD GLN A 257 7.853 27.558 7.488 1.00 67.27 C +ANISOU 2052 CD GLN A 257 13354 7629 4574 -895 -1358 969 C +ATOM 2053 OE1 GLN A 257 7.778 28.767 7.736 1.00 67.94 O +ANISOU 2053 OE1 GLN A 257 13441 7633 4740 -887 -1464 1079 O +ATOM 2054 NE2 GLN A 257 7.144 26.969 6.513 1.00 68.70 N +ANISOU 2054 NE2 GLN A 257 13742 7767 4594 -966 -1544 981 N +ATOM 2055 N ARG A 258 12.707 28.039 10.263 1.00 59.31 N +ANISOU 2055 N ARG A 258 11721 7006 3806 -856 -173 706 N +ATOM 2056 CA ARG A 258 13.961 28.796 10.356 1.00 59.15 C +ANISOU 2056 CA ARG A 258 11700 7032 3743 -955 45 715 C +ATOM 2057 C ARG A 258 15.104 27.890 10.848 1.00 57.72 C +ANISOU 2057 C ARG A 258 11314 6987 3628 -918 353 563 C +ATOM 2058 O ARG A 258 16.226 27.946 10.360 1.00 58.61 O +ANISOU 2058 O ARG A 258 11489 7165 3612 -1044 594 518 O +ATOM 2059 CB ARG A 258 13.786 29.980 11.312 1.00 58.65 C +ANISOU 2059 CB ARG A 258 11506 6901 3878 -887 -67 804 C +ATOM 2060 CG ARG A 258 12.549 30.845 11.059 1.00 59.80 C +ANISOU 2060 CG ARG A 258 11784 6892 4042 -870 -398 943 C +ATOM 2061 CD ARG A 258 12.332 31.870 12.186 1.00 58.76 C +ANISOU 2061 CD ARG A 258 11477 6693 4154 -766 -488 995 C +ATOM 2062 NE ARG A 258 13.146 33.054 11.934 1.00 60.41 N +ANISOU 2062 NE ARG A 258 11822 6862 4269 -905 -420 1079 N +ATOM 2063 CZ ARG A 258 12.987 34.233 12.526 1.00 59.74 C +ANISOU 2063 CZ ARG A 258 11701 6676 4320 -874 -529 1157 C +ATOM 2064 NH1 ARG A 258 12.035 34.397 13.437 1.00 58.73 N +ANISOU 2064 NH1 ARG A 258 11394 6483 4438 -700 -698 1152 N +ATOM 2065 NH2 ARG A 258 13.792 35.243 12.204 1.00 60.29 N +ANISOU 2065 NH2 ARG A 258 11916 6709 4282 -1024 -456 1233 N +ATOM 2066 N TRP A 259 14.787 27.051 11.823 1.00 55.44 N +ANISOU 2066 N TRP A 259 10778 6734 3552 -747 338 483 N +ATOM 2067 CA TRP A 259 15.748 26.150 12.465 1.00 54.37 C +ANISOU 2067 CA TRP A 259 10421 6706 3530 -677 576 346 C +ATOM 2068 C TRP A 259 16.470 25.239 11.469 1.00 56.83 C +ANISOU 2068 C TRP A 259 10849 7083 3659 -768 791 235 C +ATOM 2069 O TRP A 259 17.689 25.135 11.489 1.00 57.20 O +ANISOU 2069 O TRP A 259 10811 7209 3713 -813 1043 156 O +ATOM 2070 CB TRP A 259 14.980 25.360 13.517 1.00 51.68 C +ANISOU 2070 CB TRP A 259 9868 6361 3407 -494 460 303 C +ATOM 2071 CG TRP A 259 15.653 24.237 14.216 1.00 50.10 C +ANISOU 2071 CG TRP A 259 9456 6241 3338 -396 627 174 C +ATOM 2072 CD1 TRP A 259 15.317 22.929 14.128 1.00 49.79 C +ANISOU 2072 CD1 TRP A 259 9393 6214 3310 -327 631 84 C +ATOM 2073 CD2 TRP A 259 16.702 24.321 15.195 1.00 48.58 C +ANISOU 2073 CD2 TRP A 259 9041 6110 3305 -348 779 129 C +ATOM 2074 NE1 TRP A 259 16.110 22.175 14.965 1.00 49.40 N +ANISOU 2074 NE1 TRP A 259 9128 6223 3416 -235 777 -12 N +ATOM 2075 CE2 TRP A 259 16.958 23.004 15.647 1.00 47.73 C +ANISOU 2075 CE2 TRP A 259 8786 6045 3303 -243 861 14 C +ATOM 2076 CE3 TRP A 259 17.454 25.371 15.725 1.00 47.89 C +ANISOU 2076 CE3 TRP A 259 8871 6038 3286 -387 840 176 C +ATOM 2077 CZ2 TRP A 259 17.953 22.705 16.572 1.00 46.15 C +ANISOU 2077 CZ2 TRP A 259 8364 5901 3271 -176 990 -49 C +ATOM 2078 CZ3 TRP A 259 18.441 25.073 16.645 1.00 47.02 C +ANISOU 2078 CZ3 TRP A 259 8533 5991 3338 -327 974 106 C +ATOM 2079 CH2 TRP A 259 18.678 23.745 17.062 1.00 46.23 C +ANISOU 2079 CH2 TRP A 259 8290 5931 3342 -219 1040 -2 C +ATOM 2080 N VAL A 260 15.720 24.613 10.574 1.00 59.21 N +ANISOU 2080 N VAL A 260 11346 7348 3800 -802 693 223 N +ATOM 2081 CA VAL A 260 16.307 23.679 9.598 1.00 62.21 C +ANISOU 2081 CA VAL A 260 11861 7780 3996 -887 897 100 C +ATOM 2082 C VAL A 260 17.132 24.335 8.462 1.00 65.97 C +ANISOU 2082 C VAL A 260 12582 8276 4207 -1105 1076 115 C +ATOM 2083 O VAL A 260 17.844 23.643 7.737 1.00 66.66 O +ANISOU 2083 O VAL A 260 12751 8419 4155 -1184 1312 -8 O +ATOM 2084 CB VAL A 260 15.237 22.716 9.018 1.00 62.86 C +ANISOU 2084 CB VAL A 260 12085 7813 3984 -862 732 71 C +ATOM 2085 CG1 VAL A 260 14.499 22.008 10.175 1.00 60.75 C +ANISOU 2085 CG1 VAL A 260 11564 7533 3983 -664 592 46 C +ATOM 2086 CG2 VAL A 260 14.263 23.430 8.071 1.00 63.42 C +ANISOU 2086 CG2 VAL A 260 12458 7791 3848 -982 482 207 C +ATOM 2087 N ARG A 261 17.071 25.657 8.337 1.00 68.83 N +ANISOU 2087 N ARG A 261 13057 8589 4506 -1204 981 259 N +ATOM 2088 CA ARG A 261 17.904 26.392 7.378 1.00 73.09 C +ANISOU 2088 CA ARG A 261 13823 9144 4804 -1427 1158 288 C +ATOM 2089 C ARG A 261 19.290 26.762 7.922 1.00 73.41 C +ANISOU 2089 C ARG A 261 13651 9274 4968 -1455 1442 229 C +ATOM 2090 O ARG A 261 20.118 27.288 7.189 1.00 74.19 O +ANISOU 2090 O ARG A 261 13898 9402 4888 -1647 1642 231 O +ATOM 2091 CB ARG A 261 17.206 27.690 6.965 1.00 76.35 C +ANISOU 2091 CB ARG A 261 14476 9441 5090 -1534 906 483 C +ATOM 2092 CG ARG A 261 15.841 27.503 6.346 1.00 79.47 C +ANISOU 2092 CG ARG A 261 15094 9733 5365 -1528 591 562 C +ATOM 2093 CD ARG A 261 15.189 28.843 5.997 1.00 82.46 C +ANISOU 2093 CD ARG A 261 15691 9981 5656 -1618 320 761 C +ATOM 2094 NE ARG A 261 13.737 28.691 5.943 1.00 84.99 N +ANISOU 2094 NE ARG A 261 16066 10197 6027 -1520 -40 835 N +ATOM 2095 CZ ARG A 261 13.062 28.069 4.967 1.00 89.14 C +ANISOU 2095 CZ ARG A 261 16834 10685 6349 -1587 -176 833 C +ATOM 2096 NH1 ARG A 261 13.682 27.552 3.898 1.00 90.07 N +ANISOU 2096 NH1 ARG A 261 17201 10854 6167 -1762 25 759 N +ATOM 2097 NH2 ARG A 261 11.736 27.977 5.048 1.00 90.48 N +ANISOU 2097 NH2 ARG A 261 16999 10760 6618 -1485 -518 901 N +ATOM 2098 N LEU A 262 19.543 26.505 9.206 1.00 72.51 N +ANISOU 2098 N LEU A 262 13195 9200 5155 -1277 1456 180 N +ATOM 2099 CA LEU A 262 20.774 26.970 9.847 1.00 73.44 C +ANISOU 2099 CA LEU A 262 13091 9389 5422 -1295 1665 144 C +ATOM 2100 C LEU A 262 21.978 26.096 9.487 1.00 76.27 C +ANISOU 2100 C LEU A 262 13347 9855 5775 -1332 2007 -34 C +ATOM 2101 O LEU A 262 21.872 24.880 9.402 1.00 75.89 O +ANISOU 2101 O LEU A 262 13245 9831 5757 -1233 2059 -157 O +ATOM 2102 CB LEU A 262 20.592 27.021 11.360 1.00 70.78 C +ANISOU 2102 CB LEU A 262 12448 9049 5395 -1101 1535 161 C +ATOM 2103 CG LEU A 262 19.476 27.948 11.856 1.00 69.50 C +ANISOU 2103 CG LEU A 262 12342 8781 5284 -1051 1229 316 C +ATOM 2104 CD1 LEU A 262 19.190 27.689 13.325 1.00 66.53 C +ANISOU 2104 CD1 LEU A 262 11678 8407 5193 -851 1123 297 C +ATOM 2105 CD2 LEU A 262 19.823 29.413 11.638 1.00 70.50 C +ANISOU 2105 CD2 LEU A 262 12593 8861 5332 -1204 1220 439 C +ATOM 2106 N ASP A 263 23.124 26.742 9.297 1.00 80.40 N +ANISOU 2106 N ASP A 263 13834 10435 6279 -1475 2239 -51 N +ATOM 2107 CA ASP A 263 24.366 26.086 8.888 1.00 84.24 C +ANISOU 2107 CA ASP A 263 14211 11022 6773 -1533 2594 -225 C +ATOM 2108 C ASP A 263 24.830 24.984 9.858 1.00 84.47 C +ANISOU 2108 C ASP A 263 13881 11105 7107 -1316 2660 -369 C +ATOM 2109 O ASP A 263 24.823 25.182 11.069 1.00 80.46 O +ANISOU 2109 O ASP A 263 13133 10592 6845 -1180 2525 -325 O +ATOM 2110 CB ASP A 263 25.460 27.150 8.765 1.00 87.54 C +ANISOU 2110 CB ASP A 263 14597 11486 7177 -1716 2794 -196 C +ATOM 2111 CG ASP A 263 26.825 26.561 8.473 1.00 90.87 C +ANISOU 2111 CG ASP A 263 14840 12018 7667 -1770 3175 -384 C +ATOM 2112 OD1 ASP A 263 27.023 26.023 7.363 1.00 94.53 O +ANISOU 2112 OD1 ASP A 263 15490 12509 7917 -1884 3383 -489 O +ATOM 2113 OD2 ASP A 263 27.703 26.653 9.362 1.00 93.37 O +ANISOU 2113 OD2 ASP A 263 14828 12390 8257 -1701 3262 -433 O +ATOM 2114 N GLU A 264 25.265 23.845 9.308 1.00 87.69 N +ANISOU 2114 N GLU A 264 14268 11557 7491 -1293 2871 -543 N +ATOM 2115 CA GLU A 264 25.749 22.686 10.093 1.00 87.91 C +ANISOU 2115 CA GLU A 264 13979 11619 7801 -1090 2940 -691 C +ATOM 2116 C GLU A 264 26.944 23.001 11.022 1.00 86.12 C +ANISOU 2116 C GLU A 264 13402 11457 7862 -1046 3061 -729 C +ATOM 2117 O GLU A 264 26.990 22.501 12.145 1.00 85.11 O +ANISOU 2117 O GLU A 264 13016 11322 8000 -857 2945 -748 O +ATOM 2118 CB GLU A 264 26.091 21.509 9.141 1.00 93.23 C +ANISOU 2118 CB GLU A 264 14729 12317 8375 -1102 3179 -884 C +ATOM 2119 CG GLU A 264 26.687 20.241 9.782 1.00 95.35 C +ANISOU 2119 CG GLU A 264 14690 12604 8931 -899 3276 -1056 C +ATOM 2120 CD GLU A 264 25.650 19.288 10.388 1.00 95.11 C +ANISOU 2120 CD GLU A 264 14646 12501 8991 -702 3015 -1042 C +ATOM 2121 OE1 GLU A 264 25.014 18.534 9.606 1.00 97.37 O +ANISOU 2121 OE1 GLU A 264 15149 12746 9101 -712 3006 -1101 O +ATOM 2122 OE2 GLU A 264 25.499 19.266 11.646 1.00 91.08 O +ANISOU 2122 OE2 GLU A 264 13911 11971 8722 -547 2827 -978 O +ATOM 2123 N ARG A 265 27.904 23.804 10.556 1.00 86.21 N +ANISOU 2123 N ARG A 265 13410 11526 7818 -1228 3287 -740 N +ATOM 2124 CA ARG A 265 29.040 24.237 11.393 1.00 84.41 C +ANISOU 2124 CA ARG A 265 12854 11357 7860 -1215 3387 -764 C +ATOM 2125 C ARG A 265 28.581 25.128 12.566 1.00 80.44 C +ANISOU 2125 C ARG A 265 12271 10809 7482 -1153 3097 -594 C +ATOM 2126 O ARG A 265 28.798 24.784 13.734 1.00 80.46 O +ANISOU 2126 O ARG A 265 12001 10814 7756 -986 2989 -611 O +ATOM 2127 CB ARG A 265 30.105 24.961 10.559 1.00 86.25 C +ANISOU 2127 CB ARG A 265 13121 11659 7987 -1454 3699 -808 C +ATOM 2128 N GLU A 266 27.928 26.248 12.261 1.00 77.49 N +ANISOU 2128 N GLU A 266 12149 10385 6909 -1286 2965 -433 N +ATOM 2129 CA GLU A 266 27.517 27.213 13.299 1.00 74.01 C +ANISOU 2129 CA GLU A 266 11652 9891 6575 -1245 2715 -281 C +ATOM 2130 C GLU A 266 26.454 26.689 14.287 1.00 68.76 C +ANISOU 2130 C GLU A 266 10926 9165 6033 -1026 2427 -238 C +ATOM 2131 O GLU A 266 26.453 27.084 15.442 1.00 67.17 O +ANISOU 2131 O GLU A 266 10559 8947 6015 -942 2282 -183 O +ATOM 2132 CB GLU A 266 27.030 28.520 12.652 1.00 74.64 C +ANISOU 2132 CB GLU A 266 12034 9910 6414 -1436 2637 -124 C +ATOM 2133 N PHE A 267 25.564 25.814 13.820 1.00 66.88 N +ANISOU 2133 N PHE A 267 10831 8893 5684 -950 2354 -267 N +ATOM 2134 CA PHE A 267 24.454 25.284 14.625 1.00 63.81 C +ANISOU 2134 CA PHE A 267 10412 8446 5386 -767 2095 -227 C +ATOM 2135 C PHE A 267 24.226 23.770 14.415 1.00 63.13 C +ANISOU 2135 C PHE A 267 10297 8367 5323 -642 2132 -354 C +ATOM 2136 O PHE A 267 23.177 23.367 13.884 1.00 60.53 O +ANISOU 2136 O PHE A 267 10164 7985 4846 -627 2014 -331 O +ATOM 2137 CB PHE A 267 23.148 25.999 14.269 1.00 63.01 C +ANISOU 2137 CB PHE A 267 10576 8257 5107 -812 1869 -83 C +ATOM 2138 CG PHE A 267 23.138 27.463 14.573 1.00 62.69 C +ANISOU 2138 CG PHE A 267 10581 8176 5059 -905 1778 51 C +ATOM 2139 CD1 PHE A 267 22.904 27.919 15.862 1.00 60.38 C +ANISOU 2139 CD1 PHE A 267 10128 7853 4960 -800 1617 108 C +ATOM 2140 CD2 PHE A 267 23.320 28.397 13.559 1.00 64.65 C +ANISOU 2140 CD2 PHE A 267 11063 8406 5095 -1106 1847 122 C +ATOM 2141 CE1 PHE A 267 22.890 29.276 16.141 1.00 60.55 C +ANISOU 2141 CE1 PHE A 267 10202 7824 4978 -884 1534 222 C +ATOM 2142 CE2 PHE A 267 23.287 29.760 13.828 1.00 64.46 C +ANISOU 2142 CE2 PHE A 267 11098 8324 5068 -1193 1749 250 C +ATOM 2143 CZ PHE A 267 23.074 30.199 15.122 1.00 62.35 C +ANISOU 2143 CZ PHE A 267 10654 8025 5010 -1076 1594 296 C +ATOM 2144 N PRO A 268 25.183 22.924 14.848 1.00 64.35 N +ANISOU 2144 N PRO A 268 10203 8572 5675 -550 2278 -486 N +ATOM 2145 CA PRO A 268 25.060 21.471 14.605 1.00 65.25 C +ANISOU 2145 CA PRO A 268 10294 8678 5820 -434 2328 -617 C +ATOM 2146 C PRO A 268 23.751 20.852 15.139 1.00 63.58 C +ANISOU 2146 C PRO A 268 10141 8394 5623 -298 2069 -564 C +ATOM 2147 O PRO A 268 23.128 21.399 16.043 1.00 61.81 O +ANISOU 2147 O PRO A 268 9878 8136 5469 -249 1864 -449 O +ATOM 2148 CB PRO A 268 26.283 20.873 15.326 1.00 65.61 C +ANISOU 2148 CB PRO A 268 10015 8767 6144 -331 2458 -735 C +ATOM 2149 CG PRO A 268 26.796 21.950 16.229 1.00 64.79 C +ANISOU 2149 CG PRO A 268 9754 8687 6173 -363 2398 -642 C +ATOM 2150 CD PRO A 268 26.402 23.255 15.611 1.00 64.89 C +ANISOU 2150 CD PRO A 268 9995 8695 5965 -542 2381 -519 C +ATOM 2151 N GLU A 269 23.346 19.736 14.542 1.00 64.28 N +ANISOU 2151 N GLU A 269 10326 8456 5638 -251 2094 -655 N +ATOM 2152 CA GLU A 269 22.152 18.974 14.929 1.00 63.18 C +ANISOU 2152 CA GLU A 269 10240 8250 5515 -136 1878 -627 C +ATOM 2153 C GLU A 269 20.795 19.681 14.739 1.00 59.94 C +ANISOU 2153 C GLU A 269 10036 7788 4948 -191 1653 -483 C +ATOM 2154 O GLU A 269 19.787 19.238 15.273 1.00 56.21 O +ANISOU 2154 O GLU A 269 9562 7265 4529 -98 1460 -444 O +ATOM 2155 CB GLU A 269 22.304 18.402 16.351 1.00 64.79 C +ANISOU 2155 CB GLU A 269 10190 8439 5988 32 1777 -635 C +ATOM 2156 CG GLU A 269 23.513 17.474 16.531 1.00 69.28 C +ANISOU 2156 CG GLU A 269 10552 9031 6740 118 1952 -784 C +ATOM 2157 CD GLU A 269 23.384 16.484 17.708 1.00 72.01 C +ANISOU 2157 CD GLU A 269 10728 9325 7304 293 1813 -801 C +ATOM 2158 OE1 GLU A 269 22.566 16.713 18.651 1.00 73.14 O +ANISOU 2158 OE1 GLU A 269 10864 9435 7488 338 1602 -690 O +ATOM 2159 OE2 GLU A 269 24.094 15.439 17.670 1.00 74.73 O +ANISOU 2159 OE2 GLU A 269 10956 9655 7781 383 1921 -932 O +ATOM 2160 N ALA A 270 20.763 20.740 13.934 1.00 60.64 N +ANISOU 2160 N ALA A 270 10306 7884 4850 -346 1678 -409 N +ATOM 2161 CA ALA A 270 19.508 21.398 13.539 1.00 60.33 C +ANISOU 2161 CA ALA A 270 10484 7782 4655 -405 1461 -279 C +ATOM 2162 C ALA A 270 18.959 20.912 12.170 1.00 63.59 C +ANISOU 2162 C ALA A 270 11178 8166 4816 -499 1463 -313 C +ATOM 2163 O ALA A 270 17.749 20.830 11.984 1.00 63.23 O +ANISOU 2163 O ALA A 270 11263 8057 4703 -485 1246 -246 O +ATOM 2164 CB ALA A 270 19.707 22.893 13.530 1.00 59.50 C +ANISOU 2164 CB ALA A 270 10432 7675 4500 -517 1438 -159 C +ATOM 2165 N LYS A 271 19.838 20.590 11.222 1.00 67.41 N +ANISOU 2165 N LYS A 271 11753 8694 5163 -600 1709 -421 N +ATOM 2166 CA LYS A 271 19.419 19.959 9.957 1.00 71.23 C +ANISOU 2166 CA LYS A 271 12509 9153 5400 -690 1738 -482 C +ATOM 2167 C LYS A 271 19.318 18.436 10.081 1.00 72.02 C +ANISOU 2167 C LYS A 271 12532 9241 5591 -561 1773 -626 C +ATOM 2168 O LYS A 271 18.272 17.848 9.802 1.00 72.16 O +ANISOU 2168 O LYS A 271 12682 9199 5534 -538 1599 -616 O +ATOM 2169 CB LYS A 271 20.400 20.282 8.817 1.00 74.37 C +ANISOU 2169 CB LYS A 271 13073 9601 5582 -876 2015 -549 C +ATOM 2170 CG LYS A 271 20.036 21.489 7.969 1.00 76.09 C +ANISOU 2170 CG LYS A 271 13582 9788 5539 -1072 1933 -406 C +ATOM 2171 CD LYS A 271 20.935 21.633 6.747 1.00 78.54 C +ANISOU 2171 CD LYS A 271 14099 10144 5595 -1279 2225 -487 C +ATOM 2172 CE LYS A 271 22.315 22.165 7.120 1.00 79.36 C +ANISOU 2172 CE LYS A 271 13988 10332 5830 -1321 2496 -534 C +ATOM 2173 NZ LYS A 271 23.387 21.842 6.134 1.00 82.55 N +ANISOU 2173 NZ LYS A 271 14480 10804 6081 -1470 2866 -692 N +ATOM 2174 N ASN A 272 20.421 17.809 10.490 1.00 73.60 N +ANISOU 2174 N ASN A 272 12512 9488 5961 -481 1992 -761 N +ATOM 2175 CA ASN A 272 20.563 16.340 10.450 1.00 74.45 C +ANISOU 2175 CA ASN A 272 12562 9576 6149 -371 2075 -923 C +ATOM 2176 C ASN A 272 19.724 15.540 11.474 1.00 69.44 C +ANISOU 2176 C ASN A 272 11796 8881 5707 -198 1848 -897 C +ATOM 2177 O ASN A 272 19.510 14.335 11.295 1.00 69.91 O +ANISOU 2177 O ASN A 272 11883 8896 5783 -129 1857 -1006 O +ATOM 2178 CB ASN A 272 22.048 15.946 10.591 1.00 78.10 C +ANISOU 2178 CB ASN A 272 12808 10095 6771 -328 2371 -1078 C +ATOM 2179 CG ASN A 272 22.661 16.403 11.920 1.00 78.35 C +ANISOU 2179 CG ASN A 272 12524 10159 7085 -223 2337 -1022 C +ATOM 2180 OD1 ASN A 272 22.970 17.588 12.095 1.00 80.44 O +ANISOU 2180 OD1 ASN A 272 12759 10466 7337 -309 2344 -922 O +ATOM 2181 ND2 ASN A 272 22.852 15.464 12.852 1.00 76.48 N +ANISOU 2181 ND2 ASN A 272 12066 9893 7098 -46 2292 -1084 N +ATOM 2182 N ALA A 273 19.246 16.192 12.537 1.00 64.16 N +ANISOU 2182 N ALA A 273 10995 8206 5175 -137 1656 -760 N +ATOM 2183 CA ALA A 273 18.570 15.479 13.628 1.00 60.16 C +ANISOU 2183 CA ALA A 273 10345 7651 4860 13 1475 -738 C +ATOM 2184 C ALA A 273 17.186 16.035 13.972 1.00 56.57 C +ANISOU 2184 C ALA A 273 9961 7155 4377 5 1204 -591 C +ATOM 2185 O ALA A 273 16.956 17.232 13.907 1.00 56.67 O +ANISOU 2185 O ALA A 273 10026 7179 4324 -69 1135 -478 O +ATOM 2186 CB ALA A 273 19.462 15.471 14.860 1.00 58.70 C +ANISOU 2186 CB ALA A 273 9874 7495 4932 125 1528 -751 C +ATOM 2187 N PRO A 274 16.252 15.157 14.355 1.00 53.98 N +ANISOU 2187 N PRO A 274 9625 6771 4114 84 1051 -596 N +ATOM 2188 CA PRO A 274 14.938 15.663 14.783 1.00 51.74 C +ANISOU 2188 CA PRO A 274 9362 6449 3847 87 806 -469 C +ATOM 2189 C PRO A 274 15.020 16.518 16.043 1.00 49.71 C +ANISOU 2189 C PRO A 274 8914 6213 3760 144 750 -377 C +ATOM 2190 O PRO A 274 15.924 16.338 16.880 1.00 49.07 O +ANISOU 2190 O PRO A 274 8655 6162 3827 215 852 -415 O +ATOM 2191 CB PRO A 274 14.119 14.389 15.059 1.00 51.22 C +ANISOU 2191 CB PRO A 274 9286 6326 3850 160 698 -516 C +ATOM 2192 CG PRO A 274 15.110 13.280 15.179 1.00 52.06 C +ANISOU 2192 CG PRO A 274 9312 6432 4035 232 869 -652 C +ATOM 2193 CD PRO A 274 16.396 13.697 14.520 1.00 53.52 C +ANISOU 2193 CD PRO A 274 9514 6675 4146 178 1097 -718 C +ATOM 2194 N LEU A 275 14.070 17.437 16.183 1.00 47.93 N +ANISOU 2194 N LEU A 275 8727 5963 3519 114 580 -262 N +ATOM 2195 CA LEU A 275 14.081 18.365 17.289 1.00 45.16 C +ANISOU 2195 CA LEU A 275 8227 5623 3306 153 530 -181 C +ATOM 2196 C LEU A 275 13.738 17.625 18.564 1.00 43.40 C +ANISOU 2196 C LEU A 275 7836 5385 3267 264 474 -198 C +ATOM 2197 O LEU A 275 12.631 17.119 18.688 1.00 43.54 O +ANISOU 2197 O LEU A 275 7872 5360 3310 287 342 -188 O +ATOM 2198 CB LEU A 275 13.072 19.477 17.059 1.00 44.76 C +ANISOU 2198 CB LEU A 275 8266 5533 3207 103 359 -68 C +ATOM 2199 CG LEU A 275 13.054 20.535 18.164 1.00 44.25 C +ANISOU 2199 CG LEU A 275 8065 5468 3280 140 314 5 C +ATOM 2200 CD1 LEU A 275 14.321 21.384 18.110 1.00 44.57 C +ANISOU 2200 CD1 LEU A 275 8090 5553 3289 84 461 16 C +ATOM 2201 CD2 LEU A 275 11.807 21.400 18.101 1.00 44.36 C +ANISOU 2201 CD2 LEU A 275 8131 5418 3304 129 117 99 C +ATOM 2202 N LYS A 276 14.665 17.595 19.521 1.00 41.73 N +ANISOU 2202 N LYS A 276 7467 5206 3182 320 564 -219 N +ATOM 2203 CA LYS A 276 14.407 16.951 20.805 1.00 40.33 C +ANISOU 2203 CA LYS A 276 7152 5008 3161 409 506 -224 C +ATOM 2204 C LYS A 276 13.551 17.889 21.637 1.00 37.62 C +ANISOU 2204 C LYS A 276 6763 4650 2879 409 386 -134 C +ATOM 2205 O LYS A 276 13.629 19.127 21.490 1.00 37.78 O +ANISOU 2205 O LYS A 276 6806 4681 2865 362 377 -74 O +ATOM 2206 CB LYS A 276 15.707 16.605 21.535 1.00 42.02 C +ANISOU 2206 CB LYS A 276 7224 5250 3488 464 617 -271 C +ATOM 2207 CG LYS A 276 16.749 15.872 20.677 1.00 45.36 C +ANISOU 2207 CG LYS A 276 7663 5691 3878 468 771 -376 C +ATOM 2208 CD LYS A 276 18.037 15.559 21.426 1.00 47.64 C +ANISOU 2208 CD LYS A 276 7780 5999 4318 534 859 -423 C +ATOM 2209 CE LYS A 276 17.762 14.461 22.450 1.00 50.57 C +ANISOU 2209 CE LYS A 276 8080 6314 4819 629 765 -435 C +ATOM 2210 NZ LYS A 276 18.913 14.070 23.337 1.00 52.66 N +ANISOU 2210 NZ LYS A 276 8179 6575 5251 705 794 -466 N +ATOM 2211 N TYR A 277 12.713 17.314 22.492 1.00 34.44 N +ANISOU 2211 N TYR A 277 6304 4215 2566 456 299 -129 N +ATOM 2212 CA TYR A 277 11.825 18.108 23.320 1.00 32.76 C +ANISOU 2212 CA TYR A 277 6038 3985 2424 458 205 -66 C +ATOM 2213 C TYR A 277 12.651 18.985 24.299 1.00 31.54 C +ANISOU 2213 C TYR A 277 5791 3858 2334 467 258 -37 C +ATOM 2214 O TYR A 277 12.175 20.029 24.730 1.00 30.49 O +ANISOU 2214 O TYR A 277 5639 3712 2231 454 209 11 O +ATOM 2215 CB TYR A 277 10.809 17.199 24.074 1.00 32.47 C +ANISOU 2215 CB TYR A 277 5956 3913 2468 491 133 -79 C +ATOM 2216 CG TYR A 277 11.373 16.556 25.330 1.00 31.91 C +ANISOU 2216 CG TYR A 277 5795 3844 2483 532 177 -98 C +ATOM 2217 CD1 TYR A 277 12.072 15.362 25.270 1.00 32.34 C +ANISOU 2217 CD1 TYR A 277 5853 3888 2544 566 222 -151 C +ATOM 2218 CD2 TYR A 277 11.225 17.157 26.571 1.00 31.32 C +ANISOU 2218 CD2 TYR A 277 5645 3771 2481 536 165 -64 C +ATOM 2219 CE1 TYR A 277 12.594 14.778 26.416 1.00 32.29 C +ANISOU 2219 CE1 TYR A 277 5779 3868 2619 603 232 -156 C +ATOM 2220 CE2 TYR A 277 11.752 16.577 27.719 1.00 31.12 C +ANISOU 2220 CE2 TYR A 277 5567 3741 2513 560 186 -71 C +ATOM 2221 CZ TYR A 277 12.437 15.404 27.634 1.00 31.59 C +ANISOU 2221 CZ TYR A 277 5633 3786 2582 594 208 -110 C +ATOM 2222 OH TYR A 277 12.964 14.837 28.770 1.00 32.83 O +ANISOU 2222 OH TYR A 277 5749 3924 2799 617 198 -105 O +ATOM 2223 N THR A 278 13.874 18.570 24.643 1.00 30.74 N +ANISOU 2223 N THR A 278 5629 3786 2263 489 348 -73 N +ATOM 2224 CA THR A 278 14.719 19.389 25.506 1.00 30.40 C +ANISOU 2224 CA THR A 278 5501 3768 2279 485 383 -47 C +ATOM 2225 C THR A 278 15.302 20.631 24.805 1.00 31.09 C +ANISOU 2225 C THR A 278 5626 3882 2304 422 434 -16 C +ATOM 2226 O THR A 278 15.662 21.618 25.474 1.00 31.27 O +ANISOU 2226 O THR A 278 5602 3911 2367 401 432 20 O +ATOM 2227 CB THR A 278 15.864 18.576 26.166 1.00 30.27 C +ANISOU 2227 CB THR A 278 5390 3767 2342 530 435 -90 C +ATOM 2228 OG1 THR A 278 16.411 17.648 25.220 1.00 31.17 O +ANISOU 2228 OG1 THR A 278 5524 3887 2429 550 508 -157 O +ATOM 2229 CG2 THR A 278 15.357 17.814 27.344 1.00 29.16 C +ANISOU 2229 CG2 THR A 278 5215 3591 2272 572 362 -85 C +ATOM 2230 N SER A 279 15.394 20.595 23.480 1.00 31.88 N +ANISOU 2230 N SER A 279 5824 3991 2296 379 478 -31 N +ATOM 2231 CA SER A 279 15.750 21.782 22.718 1.00 32.66 C +ANISOU 2231 CA SER A 279 5998 4102 2309 297 514 11 C +ATOM 2232 C SER A 279 14.563 22.732 22.607 1.00 32.70 C +ANISOU 2232 C SER A 279 6083 4053 2288 276 385 86 C +ATOM 2233 O SER A 279 14.739 23.936 22.432 1.00 33.95 O +ANISOU 2233 O SER A 279 6284 4198 2417 220 377 142 O +ATOM 2234 CB SER A 279 16.248 21.393 21.339 1.00 33.89 C +ANISOU 2234 CB SER A 279 6256 4281 2337 243 615 -31 C +ATOM 2235 OG SER A 279 17.319 20.468 21.423 1.00 34.42 O +ANISOU 2235 OG SER A 279 6231 4389 2458 278 741 -117 O +ATOM 2236 N ALA A 280 13.348 22.203 22.702 1.00 31.84 N +ANISOU 2236 N ALA A 280 5988 3906 2204 319 278 85 N +ATOM 2237 CA ALA A 280 12.158 23.037 22.707 1.00 31.26 C +ANISOU 2237 CA ALA A 280 5951 3773 2153 317 145 144 C +ATOM 2238 C ALA A 280 12.035 23.769 24.019 1.00 29.82 C +ANISOU 2238 C ALA A 280 5663 3575 2092 351 130 162 C +ATOM 2239 O ALA A 280 11.651 24.927 24.041 1.00 30.26 O +ANISOU 2239 O ALA A 280 5744 3584 2169 336 69 211 O +ATOM 2240 CB ALA A 280 10.910 22.208 22.459 1.00 31.44 C +ANISOU 2240 CB ALA A 280 5991 3762 2191 349 41 128 C +ATOM 2241 N LEU A 281 12.332 23.073 25.103 1.00 28.44 N +ANISOU 2241 N LEU A 281 5385 3428 1993 393 178 120 N +ATOM 2242 CA LEU A 281 12.341 23.653 26.455 1.00 27.07 C +ANISOU 2242 CA LEU A 281 5128 3244 1912 411 179 125 C +ATOM 2243 C LEU A 281 13.432 24.695 26.627 1.00 27.14 C +ANISOU 2243 C LEU A 281 5132 3268 1910 368 232 150 C +ATOM 2244 O LEU A 281 13.270 25.660 27.355 1.00 26.13 O +ANISOU 2244 O LEU A 281 4986 3108 1832 362 209 169 O +ATOM 2245 CB LEU A 281 12.548 22.560 27.475 1.00 26.13 C +ANISOU 2245 CB LEU A 281 4933 3149 1845 447 211 82 C +ATOM 2246 CG LEU A 281 11.322 21.679 27.707 1.00 26.01 C +ANISOU 2246 CG LEU A 281 4908 3108 1867 478 159 59 C +ATOM 2247 CD1 LEU A 281 11.690 20.432 28.501 1.00 25.71 C +ANISOU 2247 CD1 LEU A 281 4829 3085 1852 500 188 26 C +ATOM 2248 CD2 LEU A 281 10.216 22.429 28.413 1.00 25.88 C +ANISOU 2248 CD2 LEU A 281 4858 3051 1924 483 114 67 C +ATOM 2249 N THR A 282 14.551 24.472 25.947 1.00 27.85 N +ANISOU 2249 N THR A 282 5237 3404 1940 333 311 141 N +ATOM 2250 CA THR A 282 15.635 25.427 25.911 1.00 28.25 C +ANISOU 2250 CA THR A 282 5281 3473 1977 272 371 165 C +ATOM 2251 C THR A 282 15.219 26.720 25.192 1.00 29.48 C +ANISOU 2251 C THR A 282 5546 3577 2077 215 323 228 C +ATOM 2252 O THR A 282 15.469 27.826 25.693 1.00 30.58 O +ANISOU 2252 O THR A 282 5681 3687 2250 183 312 260 O +ATOM 2253 CB THR A 282 16.826 24.794 25.220 1.00 28.67 C +ANISOU 2253 CB THR A 282 5314 3588 1989 244 484 127 C +ATOM 2254 OG1 THR A 282 17.329 23.751 26.060 1.00 27.69 O +ANISOU 2254 OG1 THR A 282 5077 3493 1950 305 505 76 O +ATOM 2255 CG2 THR A 282 17.917 25.815 24.944 1.00 29.52 C +ANISOU 2255 CG2 THR A 282 5419 3718 2075 157 560 151 C +ATOM 2256 N HIS A 283 14.591 26.599 24.030 1.00 30.20 N +ANISOU 2256 N HIS A 283 5747 3645 2081 198 282 249 N +ATOM 2257 CA HIS A 283 13.943 27.745 23.399 1.00 30.95 C +ANISOU 2257 CA HIS A 283 5958 3665 2135 158 188 320 C +ATOM 2258 C HIS A 283 12.995 28.468 24.356 1.00 30.24 C +ANISOU 2258 C HIS A 283 5818 3503 2168 216 88 335 C +ATOM 2259 O HIS A 283 13.042 29.691 24.454 1.00 31.70 O +ANISOU 2259 O HIS A 283 6044 3628 2371 185 53 380 O +ATOM 2260 CB HIS A 283 13.169 27.310 22.190 1.00 32.05 C +ANISOU 2260 CB HIS A 283 6218 3780 2179 146 114 338 C +ATOM 2261 CG HIS A 283 12.377 28.405 21.539 1.00 33.46 C +ANISOU 2261 CG HIS A 283 6520 3863 2328 116 -25 419 C +ATOM 2262 ND1 HIS A 283 11.061 28.667 21.868 1.00 33.84 N +ANISOU 2262 ND1 HIS A 283 6537 3834 2486 188 -174 435 N +ATOM 2263 CD2 HIS A 283 12.690 29.265 20.541 1.00 34.67 C +ANISOU 2263 CD2 HIS A 283 6834 3977 2361 19 -47 490 C +ATOM 2264 CE1 HIS A 283 10.608 29.654 21.114 1.00 34.51 C +ANISOU 2264 CE1 HIS A 283 6749 3828 2533 151 -299 514 C +ATOM 2265 NE2 HIS A 283 11.577 30.034 20.303 1.00 35.16 N +ANISOU 2265 NE2 HIS A 283 6964 3929 2464 43 -229 555 N +ATOM 2266 N ASP A 284 12.138 27.734 25.054 1.00 28.71 N +ANISOU 2266 N ASP A 284 5541 3308 2060 293 52 291 N +ATOM 2267 CA ASP A 284 11.148 28.342 25.946 1.00 27.98 C +ANISOU 2267 CA ASP A 284 5391 3149 2090 348 -17 284 C +ATOM 2268 C ASP A 284 11.806 28.981 27.198 1.00 27.05 C +ANISOU 2268 C ASP A 284 5212 3035 2030 340 47 264 C +ATOM 2269 O ASP A 284 11.319 29.977 27.728 1.00 27.22 O +ANISOU 2269 O ASP A 284 5229 2984 2127 355 8 268 O +ATOM 2270 CB ASP A 284 10.099 27.328 26.358 1.00 27.73 C +ANISOU 2270 CB ASP A 284 5283 3123 2127 411 -47 236 C +ATOM 2271 CG ASP A 284 9.153 26.896 25.192 1.00 28.79 C +ANISOU 2271 CG ASP A 284 5476 3229 2234 420 -154 256 C +ATOM 2272 OD1 ASP A 284 9.142 27.493 24.065 1.00 30.32 O +ANISOU 2272 OD1 ASP A 284 5784 3381 2352 381 -229 315 O +ATOM 2273 OD2 ASP A 284 8.388 25.927 25.423 1.00 28.29 O +ANISOU 2273 OD2 ASP A 284 5350 3178 2219 457 -172 215 O +ATOM 2274 N ALA A 285 12.926 28.428 27.648 1.00 26.01 N +ANISOU 2274 N ALA A 285 5036 2977 1867 314 139 240 N +ATOM 2275 CA ALA A 285 13.719 29.048 28.698 1.00 25.36 C +ANISOU 2275 CA ALA A 285 4915 2901 1821 286 182 230 C +ATOM 2276 C ALA A 285 14.137 30.490 28.329 1.00 25.74 C +ANISOU 2276 C ALA A 285 5032 2894 1852 224 167 280 C +ATOM 2277 O ALA A 285 14.100 31.379 29.170 1.00 25.61 O +ANISOU 2277 O ALA A 285 5012 2828 1891 217 154 273 O +ATOM 2278 CB ALA A 285 14.958 28.217 28.982 1.00 25.15 C +ANISOU 2278 CB ALA A 285 4827 2957 1771 265 256 207 C +ATOM 2279 N ILE A 286 14.551 30.705 27.082 1.00 25.81 N +ANISOU 2279 N ILE A 286 5121 2909 1776 169 173 328 N +ATOM 2280 CA ILE A 286 14.947 32.035 26.632 1.00 26.45 C +ANISOU 2280 CA ILE A 286 5291 2930 1827 92 156 387 C +ATOM 2281 C ILE A 286 13.760 32.982 26.540 1.00 26.45 C +ANISOU 2281 C ILE A 286 5359 2807 1881 131 37 420 C +ATOM 2282 O ILE A 286 13.906 34.146 26.869 1.00 26.57 O +ANISOU 2282 O ILE A 286 5413 2747 1933 100 12 443 O +ATOM 2283 CB ILE A 286 15.687 31.978 25.274 1.00 27.53 C +ANISOU 2283 CB ILE A 286 5517 3104 1838 2 209 430 C +ATOM 2284 CG1 ILE A 286 16.951 31.114 25.420 1.00 27.42 C +ANISOU 2284 CG1 ILE A 286 5405 3205 1808 -26 340 382 C +ATOM 2285 CG2 ILE A 286 16.089 33.374 24.797 1.00 28.69 C +ANISOU 2285 CG2 ILE A 286 5778 3180 1942 -97 191 502 C +ATOM 2286 CD1 ILE A 286 17.809 31.435 26.638 1.00 26.96 C +ANISOU 2286 CD1 ILE A 286 5238 3169 1835 -42 377 355 C +ATOM 2287 N LEU A 287 12.595 32.489 26.100 1.00 26.19 N +ANISOU 2287 N LEU A 287 5334 2746 1870 199 -43 417 N +ATOM 2288 CA LEU A 287 11.330 33.260 26.221 1.00 26.47 C +ANISOU 2288 CA LEU A 287 5383 2661 2013 265 -166 427 C +ATOM 2289 C LEU A 287 11.039 33.701 27.641 1.00 25.86 C +ANISOU 2289 C LEU A 287 5214 2549 2063 316 -136 362 C +ATOM 2290 O LEU A 287 10.664 34.841 27.864 1.00 26.35 O +ANISOU 2290 O LEU A 287 5307 2500 2202 332 -193 371 O +ATOM 2291 CB LEU A 287 10.120 32.468 25.754 1.00 26.50 C +ANISOU 2291 CB LEU A 287 5358 2656 2053 336 -251 415 C +ATOM 2292 CG LEU A 287 9.996 32.133 24.259 1.00 27.54 C +ANISOU 2292 CG LEU A 287 5610 2788 2065 294 -328 479 C +ATOM 2293 CD1 LEU A 287 8.630 31.526 23.987 1.00 27.84 C +ANISOU 2293 CD1 LEU A 287 5604 2794 2180 370 -445 462 C +ATOM 2294 CD2 LEU A 287 10.190 33.332 23.358 1.00 28.72 C +ANISOU 2294 CD2 LEU A 287 5919 2842 2150 227 -417 574 C +ATOM 2295 N VAL A 288 11.186 32.770 28.588 1.00 24.79 N +ANISOU 2295 N VAL A 288 4979 2498 1942 339 -50 293 N +ATOM 2296 CA VAL A 288 10.933 33.020 30.011 1.00 24.29 C +ANISOU 2296 CA VAL A 288 4847 2413 1966 369 -3 221 C +ATOM 2297 C VAL A 288 11.925 33.990 30.570 1.00 24.58 C +ANISOU 2297 C VAL A 288 4926 2428 1985 303 32 228 C +ATOM 2298 O VAL A 288 11.538 34.918 31.254 1.00 25.32 O +ANISOU 2298 O VAL A 288 5029 2434 2156 320 21 195 O +ATOM 2299 CB VAL A 288 11.014 31.717 30.826 1.00 23.28 C +ANISOU 2299 CB VAL A 288 4638 2382 1822 382 72 164 C +ATOM 2300 CG1 VAL A 288 11.230 31.986 32.314 1.00 22.99 C +ANISOU 2300 CG1 VAL A 288 4576 2343 1816 367 136 103 C +ATOM 2301 CG2 VAL A 288 9.745 30.910 30.606 1.00 23.19 C +ANISOU 2301 CG2 VAL A 288 4572 2368 1868 449 39 136 C +ATOM 2302 N ILE A 289 13.206 33.782 30.314 1.00 24.46 N +ANISOU 2302 N ILE A 289 4926 2487 1879 227 78 262 N +ATOM 2303 CA ILE A 289 14.213 34.735 30.740 1.00 25.20 C +ANISOU 2303 CA ILE A 289 5055 2559 1959 147 101 276 C +ATOM 2304 C ILE A 289 14.006 36.142 30.143 1.00 26.63 C +ANISOU 2304 C ILE A 289 5339 2616 2160 119 34 328 C +ATOM 2305 O ILE A 289 14.013 37.138 30.881 1.00 27.10 O +ANISOU 2305 O ILE A 289 5428 2594 2275 106 23 305 O +ATOM 2306 CB ILE A 289 15.641 34.249 30.448 1.00 25.07 C +ANISOU 2306 CB ILE A 289 5012 2646 1867 67 163 301 C +ATOM 2307 CG1 ILE A 289 16.030 33.152 31.425 1.00 24.31 C +ANISOU 2307 CG1 ILE A 289 4820 2638 1778 89 206 246 C +ATOM 2308 CG2 ILE A 289 16.636 35.395 30.574 1.00 25.84 C +ANISOU 2308 CG2 ILE A 289 5152 2709 1955 -33 172 331 C +ATOM 2309 CD1 ILE A 289 17.124 32.223 30.932 1.00 24.22 C +ANISOU 2309 CD1 ILE A 289 4747 2730 1723 58 259 257 C +ATOM 2310 N ALA A 290 13.821 36.248 28.838 1.00 27.66 N +ANISOU 2310 N ALA A 290 5544 2722 2242 105 -18 399 N +ATOM 2311 CA ALA A 290 13.530 37.573 28.245 1.00 29.44 C +ANISOU 2311 CA ALA A 290 5889 2808 2487 79 -109 463 C +ATOM 2312 C ALA A 290 12.301 38.232 28.876 1.00 30.38 C +ANISOU 2312 C ALA A 290 5993 2799 2752 182 -184 416 C +ATOM 2313 O ALA A 290 12.356 39.401 29.237 1.00 31.18 O +ANISOU 2313 O ALA A 290 6150 2785 2908 165 -215 417 O +ATOM 2314 CB ALA A 290 13.363 37.472 26.749 1.00 30.08 C +ANISOU 2314 CB ALA A 290 6074 2877 2479 48 -173 549 C +ATOM 2315 N GLU A 291 11.223 37.469 29.072 1.00 30.63 N +ANISOU 2315 N GLU A 291 5936 2846 2856 285 -201 363 N +ATOM 2316 CA GLU A 291 9.983 38.019 29.645 1.00 31.91 C +ANISOU 2316 CA GLU A 291 6050 2890 3182 389 -254 301 C +ATOM 2317 C GLU A 291 10.191 38.549 31.062 1.00 31.58 C +ANISOU 2317 C GLU A 291 5977 2821 3198 387 -167 210 C +ATOM 2318 O GLU A 291 9.654 39.618 31.419 1.00 32.71 O +ANISOU 2318 O GLU A 291 6145 2825 3459 430 -205 175 O +ATOM 2319 CB GLU A 291 8.830 37.000 29.633 1.00 32.33 C +ANISOU 2319 CB GLU A 291 5993 2983 3308 483 -268 253 C +ATOM 2320 CG GLU A 291 7.510 37.488 30.219 1.00 34.06 C +ANISOU 2320 CG GLU A 291 6127 3089 3723 592 -302 172 C +ATOM 2321 CD GLU A 291 6.899 38.647 29.422 1.00 37.33 C +ANISOU 2321 CD GLU A 291 6607 3331 4244 640 -464 229 C +ATOM 2322 OE1 GLU A 291 6.467 38.375 28.257 1.00 38.74 O +ANISOU 2322 OE1 GLU A 291 6818 3493 4407 654 -596 308 O +ATOM 2323 OE2 GLU A 291 6.849 39.836 29.943 1.00 39.36 O +ANISOU 2323 OE2 GLU A 291 6896 3457 4599 661 -474 196 O +ATOM 2324 N ALA A 292 10.974 37.830 31.859 1.00 30.13 N +ANISOU 2324 N ALA A 292 5752 2759 2934 335 -59 171 N +ATOM 2325 CA ALA A 292 11.232 38.246 33.226 1.00 29.95 C +ANISOU 2325 CA ALA A 292 5724 2719 2935 313 15 87 C +ATOM 2326 C ALA A 292 12.031 39.505 33.289 1.00 30.64 C +ANISOU 2326 C ALA A 292 5911 2721 3008 236 -8 117 C +ATOM 2327 O ALA A 292 11.727 40.364 34.104 1.00 31.31 O +ANISOU 2327 O ALA A 292 6025 2704 3167 252 5 47 O +ATOM 2328 CB ALA A 292 11.946 37.163 33.999 1.00 29.07 C +ANISOU 2328 CB ALA A 292 5564 2749 2732 265 101 57 C +ATOM 2329 N PHE A 293 13.062 39.632 32.448 1.00 30.59 N +ANISOU 2329 N PHE A 293 5961 2751 2908 146 -33 212 N +ATOM 2330 CA PHE A 293 13.880 40.843 32.458 1.00 31.44 C +ANISOU 2330 CA PHE A 293 6166 2776 3000 52 -55 248 C +ATOM 2331 C PHE A 293 13.165 42.033 31.861 1.00 32.35 C +ANISOU 2331 C PHE A 293 6377 2712 3200 89 -156 284 C +ATOM 2332 O PHE A 293 13.395 43.136 32.293 1.00 33.22 O +ANISOU 2332 O PHE A 293 6562 2708 3351 51 -174 269 O +ATOM 2333 CB PHE A 293 15.275 40.628 31.850 1.00 31.51 C +ANISOU 2333 CB PHE A 293 6192 2886 2894 -74 -26 327 C +ATOM 2334 CG PHE A 293 16.199 39.929 32.783 1.00 30.97 C +ANISOU 2334 CG PHE A 293 6042 2942 2783 -125 48 280 C +ATOM 2335 CD1 PHE A 293 16.865 40.640 33.771 1.00 31.91 C +ANISOU 2335 CD1 PHE A 293 6187 3026 2911 -199 56 242 C +ATOM 2336 CD2 PHE A 293 16.343 38.567 32.741 1.00 30.19 C +ANISOU 2336 CD2 PHE A 293 5846 2979 2643 -94 93 269 C +ATOM 2337 CE1 PHE A 293 17.705 39.980 34.692 1.00 31.63 C +ANISOU 2337 CE1 PHE A 293 6080 3096 2840 -247 94 203 C +ATOM 2338 CE2 PHE A 293 17.147 37.901 33.657 1.00 29.99 C +ANISOU 2338 CE2 PHE A 293 5748 3051 2594 -131 134 230 C +ATOM 2339 CZ PHE A 293 17.841 38.610 34.628 1.00 30.52 C +ANISOU 2339 CZ PHE A 293 5841 3087 2667 -209 127 201 C +ATOM 2340 N ARG A 294 12.300 41.822 30.889 1.00 32.55 N +ANISOU 2340 N ARG A 294 6406 2701 3258 162 -236 332 N +ATOM 2341 CA ARG A 294 11.450 42.927 30.381 1.00 33.88 C +ANISOU 2341 CA ARG A 294 6656 2675 3539 223 -365 364 C +ATOM 2342 C ARG A 294 10.516 43.401 31.488 1.00 34.23 C +ANISOU 2342 C ARG A 294 6638 2615 3753 332 -347 237 C +ATOM 2343 O ARG A 294 10.301 44.577 31.648 1.00 35.24 O +ANISOU 2343 O ARG A 294 6839 2574 3976 350 -404 225 O +ATOM 2344 CB ARG A 294 10.621 42.503 29.179 1.00 34.14 C +ANISOU 2344 CB ARG A 294 6695 2690 3583 285 -478 436 C +ATOM 2345 CG ARG A 294 11.421 42.327 27.882 1.00 34.32 C +ANISOU 2345 CG ARG A 294 6834 2769 3436 168 -512 567 C +ATOM 2346 CD ARG A 294 10.516 42.375 26.661 1.00 35.21 C +ANISOU 2346 CD ARG A 294 7019 2793 3564 217 -677 652 C +ATOM 2347 NE ARG A 294 9.620 41.245 26.690 1.00 34.44 N +ANISOU 2347 NE ARG A 294 6789 2778 3518 321 -678 596 N +ATOM 2348 CZ ARG A 294 9.815 40.090 26.059 1.00 33.86 C +ANISOU 2348 CZ ARG A 294 6699 2845 3320 288 -643 621 C +ATOM 2349 NH1 ARG A 294 10.869 39.879 25.267 1.00 33.87 N +ANISOU 2349 NH1 ARG A 294 6806 2927 3136 158 -594 697 N +ATOM 2350 NH2 ARG A 294 8.925 39.128 26.201 1.00 33.17 N +ANISOU 2350 NH2 ARG A 294 6488 2813 3301 383 -651 563 N +ATOM 2351 N TYR A 295 9.966 42.461 32.245 1.00 33.61 N +ANISOU 2351 N TYR A 295 6428 2631 3708 399 -257 139 N +ATOM 2352 CA TYR A 295 9.121 42.761 33.399 1.00 34.34 C +ANISOU 2352 CA TYR A 295 6453 2651 3942 485 -192 -2 C +ATOM 2353 C TYR A 295 9.864 43.625 34.438 1.00 34.41 C +ANISOU 2353 C TYR A 295 6542 2605 3924 410 -124 -65 C +ATOM 2354 O TYR A 295 9.345 44.640 34.858 1.00 35.29 O +ANISOU 2354 O TYR A 295 6687 2556 4164 463 -138 -135 O +ATOM 2355 CB TYR A 295 8.617 41.458 34.039 1.00 33.77 C +ANISOU 2355 CB TYR A 295 6248 2721 3862 526 -84 -84 C +ATOM 2356 CG TYR A 295 7.857 41.646 35.330 1.00 34.86 C +ANISOU 2356 CG TYR A 295 6324 2811 4109 582 27 -242 C +ATOM 2357 CD1 TYR A 295 6.489 41.865 35.327 1.00 36.30 C +ANISOU 2357 CD1 TYR A 295 6408 2892 4491 710 13 -321 C +ATOM 2358 CD2 TYR A 295 8.521 41.594 36.559 1.00 35.11 C +ANISOU 2358 CD2 TYR A 295 6397 2897 4045 501 147 -318 C +ATOM 2359 CE1 TYR A 295 5.797 42.061 36.504 1.00 37.71 C +ANISOU 2359 CE1 TYR A 295 6528 3026 4772 754 145 -481 C +ATOM 2360 CE2 TYR A 295 7.847 41.764 37.757 1.00 36.28 C +ANISOU 2360 CE2 TYR A 295 6516 3003 4265 532 269 -470 C +ATOM 2361 CZ TYR A 295 6.480 41.998 37.734 1.00 37.84 C +ANISOU 2361 CZ TYR A 295 6612 3103 4662 658 284 -558 C +ATOM 2362 OH TYR A 295 5.770 42.163 38.932 1.00 39.15 O +ANISOU 2362 OH TYR A 295 6741 3228 4905 685 438 -729 O +ATOM 2363 N LEU A 296 11.079 43.232 34.809 1.00 33.35 N +ANISOU 2363 N LEU A 296 6439 2597 3635 288 -62 -40 N +ATOM 2364 CA LEU A 296 11.898 43.999 35.769 1.00 34.03 C +ANISOU 2364 CA LEU A 296 6608 2640 3680 194 -18 -89 C +ATOM 2365 C LEU A 296 12.213 45.408 35.326 1.00 35.25 C +ANISOU 2365 C LEU A 296 6889 2625 3877 153 -106 -38 C +ATOM 2366 O LEU A 296 12.208 46.319 36.130 1.00 35.83 O +ANISOU 2366 O LEU A 296 7030 2580 4003 140 -87 -120 O +ATOM 2367 CB LEU A 296 13.216 43.288 36.106 1.00 33.20 C +ANISOU 2367 CB LEU A 296 6497 2700 3417 68 29 -53 C +ATOM 2368 CG LEU A 296 13.085 41.949 36.833 1.00 32.31 C +ANISOU 2368 CG LEU A 296 6289 2738 3247 87 113 -111 C +ATOM 2369 CD1 LEU A 296 14.376 41.140 36.749 1.00 31.82 C +ANISOU 2369 CD1 LEU A 296 6199 2830 3058 -12 118 -43 C +ATOM 2370 CD2 LEU A 296 12.683 42.126 38.269 1.00 32.75 C +ANISOU 2370 CD2 LEU A 296 6367 2757 3318 92 196 -247 C +ATOM 2371 N ARG A 297 12.489 45.588 34.042 1.00 35.75 N +ANISOU 2371 N ARG A 297 7002 2670 3911 122 -202 95 N +ATOM 2372 CA ARG A 297 12.709 46.916 33.512 1.00 37.48 C +ANISOU 2372 CA ARG A 297 7359 2711 4168 76 -300 161 C +ATOM 2373 C ARG A 297 11.447 47.748 33.684 1.00 39.19 C +ANISOU 2373 C ARG A 297 7588 2723 4578 218 -364 88 C +ATOM 2374 O ARG A 297 11.509 48.903 34.111 1.00 41.01 O +ANISOU 2374 O ARG A 297 7915 2785 4879 204 -389 48 O +ATOM 2375 CB ARG A 297 13.121 46.835 32.051 1.00 37.59 C +ANISOU 2375 CB ARG A 297 7437 2749 4096 10 -384 321 C +ATOM 2376 CG ARG A 297 13.251 48.178 31.334 1.00 39.18 C +ANISOU 2376 CG ARG A 297 7808 2752 4326 -43 -506 414 C +ATOM 2377 CD ARG A 297 13.616 47.996 29.860 1.00 39.31 C +ANISOU 2377 CD ARG A 297 7907 2802 4225 -126 -576 572 C +ATOM 2378 NE ARG A 297 13.554 49.288 29.175 1.00 41.23 N +ANISOU 2378 NE ARG A 297 8333 2830 4501 -171 -713 668 N +ATOM 2379 CZ ARG A 297 12.452 49.820 28.642 1.00 42.39 C +ANISOU 2379 CZ ARG A 297 8539 2794 4771 -54 -871 701 C +ATOM 2380 NH1 ARG A 297 11.287 49.173 28.679 1.00 41.91 N +ANISOU 2380 NH1 ARG A 297 8352 2747 4822 114 -906 642 N +ATOM 2381 NH2 ARG A 297 12.515 51.011 28.077 1.00 44.14 N +ANISOU 2381 NH2 ARG A 297 8945 2810 5015 -109 -1003 796 N +ATOM 2382 N ARG A 298 10.305 47.149 33.401 1.00 39.45 N +ANISOU 2382 N ARG A 298 7513 2764 4709 356 -386 61 N +ATOM 2383 CA ARG A 298 9.031 47.813 33.589 1.00 41.67 C +ANISOU 2383 CA ARG A 298 7760 2861 5212 509 -440 -24 C +ATOM 2384 C ARG A 298 8.699 48.198 35.053 1.00 42.83 C +ANISOU 2384 C ARG A 298 7871 2950 5449 551 -307 -210 C +ATOM 2385 O ARG A 298 8.083 49.232 35.297 1.00 43.94 O +ANISOU 2385 O ARG A 298 8044 2887 5762 634 -345 -284 O +ATOM 2386 CB ARG A 298 7.904 46.972 32.980 1.00 41.64 C +ANISOU 2386 CB ARG A 298 7620 2900 5301 636 -491 -16 C +ATOM 2387 CG ARG A 298 7.656 47.297 31.521 1.00 42.85 C +ANISOU 2387 CG ARG A 298 7849 2955 5474 654 -692 137 C +ATOM 2388 CD ARG A 298 6.324 46.773 31.037 1.00 43.55 C +ANISOU 2388 CD ARG A 298 7804 3021 5720 803 -781 121 C +ATOM 2389 NE ARG A 298 6.566 45.534 30.332 1.00 42.58 N +ANISOU 2389 NE ARG A 298 7649 3090 5439 749 -777 204 N +ATOM 2390 CZ ARG A 298 6.341 44.326 30.819 1.00 41.68 C +ANISOU 2390 CZ ARG A 298 7393 3149 5293 768 -652 130 C +ATOM 2391 NH1 ARG A 298 5.823 44.145 32.031 1.00 42.08 N +ANISOU 2391 NH1 ARG A 298 7319 3219 5450 831 -511 -27 N +ATOM 2392 NH2 ARG A 298 6.653 43.292 30.084 1.00 40.75 N +ANISOU 2392 NH2 ARG A 298 7273 3182 5028 713 -662 212 N +ATOM 2393 N GLN A 299 9.112 47.362 36.002 1.00 42.72 N +ANISOU 2393 N GLN A 299 7805 3108 5319 491 -155 -287 N +ATOM 2394 CA GLN A 299 8.930 47.648 37.421 1.00 44.67 C +ANISOU 2394 CA GLN A 299 8054 3319 5598 494 -16 -460 C +ATOM 2395 C GLN A 299 9.988 48.617 37.982 1.00 46.31 C +ANISOU 2395 C GLN A 299 8422 3451 5721 365 -14 -469 C +ATOM 2396 O GLN A 299 9.847 49.089 39.091 1.00 46.77 O +ANISOU 2396 O GLN A 299 8523 3439 5806 361 80 -613 O +ATOM 2397 CB GLN A 299 8.919 46.358 38.245 1.00 43.38 C +ANISOU 2397 CB GLN A 299 7799 3357 5327 467 128 -531 C +ATOM 2398 CG GLN A 299 7.830 45.366 37.859 1.00 43.18 C +ANISOU 2398 CG GLN A 299 7611 3405 5388 581 146 -544 C +ATOM 2399 CD GLN A 299 6.404 45.866 38.095 1.00 45.19 C +ANISOU 2399 CD GLN A 299 7772 3510 5886 733 176 -677 C +ATOM 2400 OE1 GLN A 299 5.534 45.710 37.243 1.00 46.22 O +ANISOU 2400 OE1 GLN A 299 7799 3599 6161 844 84 -638 O +ATOM 2401 NE2 GLN A 299 6.156 46.435 39.259 1.00 46.33 N +ANISOU 2401 NE2 GLN A 299 7947 3575 6081 737 307 -841 N +ATOM 2402 N ARG A 300 11.023 48.903 37.197 1.00 47.94 N +ANISOU 2402 N ARG A 300 8719 3670 5826 253 -113 -319 N +ATOM 2403 CA ARG A 300 12.110 49.837 37.554 1.00 50.63 C +ANISOU 2403 CA ARG A 300 9206 3938 6092 111 -134 -303 C +ATOM 2404 C ARG A 300 12.927 49.338 38.714 1.00 51.65 C +ANISOU 2404 C ARG A 300 9340 4207 6076 -3 -27 -375 C +ATOM 2405 O ARG A 300 13.299 50.092 39.626 1.00 51.93 O +ANISOU 2405 O ARG A 300 9479 4156 6096 -74 1 -462 O +ATOM 2406 CB ARG A 300 11.601 51.268 37.798 1.00 52.77 C +ANISOU 2406 CB ARG A 300 9585 3946 6519 166 -179 -380 C +ATOM 2407 CG ARG A 300 10.726 51.758 36.666 1.00 53.91 C +ANISOU 2407 CG ARG A 300 9725 3932 6826 293 -316 -305 C +ATOM 2408 CD ARG A 300 10.474 53.244 36.691 1.00 56.44 C +ANISOU 2408 CD ARG A 300 10177 3972 7295 327 -402 -339 C +ATOM 2409 NE ARG A 300 10.157 53.816 38.009 1.00 57.95 N +ANISOU 2409 NE ARG A 300 10394 4057 7567 362 -287 -540 N +ATOM 2410 CZ ARG A 300 9.110 53.474 38.763 1.00 58.27 C +ANISOU 2410 CZ ARG A 300 10314 4097 7727 497 -166 -711 C +ATOM 2411 NH1 ARG A 300 8.246 52.491 38.376 1.00 56.92 N +ANISOU 2411 NH1 ARG A 300 9968 4038 7620 613 -148 -706 N +ATOM 2412 NH2 ARG A 300 8.939 54.123 39.922 1.00 59.07 N +ANISOU 2412 NH2 ARG A 300 10476 4085 7880 503 -54 -896 N +ATOM 2413 N VAL A 301 13.223 48.044 38.647 1.00 53.20 N +ANISOU 2413 N VAL A 301 9433 4613 6165 -25 14 -332 N +ATOM 2414 CA VAL A 301 14.013 47.375 39.654 1.00 55.80 C +ANISOU 2414 CA VAL A 301 9757 5088 6355 -129 85 -375 C +ATOM 2415 C VAL A 301 15.479 47.510 39.290 1.00 60.38 C +ANISOU 2415 C VAL A 301 10376 5734 6830 -288 20 -260 C +ATOM 2416 O VAL A 301 15.871 47.397 38.121 1.00 58.88 O +ANISOU 2416 O VAL A 301 10159 5582 6630 -309 -38 -130 O +ATOM 2417 CB VAL A 301 13.632 45.897 39.747 1.00 54.35 C +ANISOU 2417 CB VAL A 301 9443 5083 6122 -74 150 -381 C +ATOM 2418 CG1 VAL A 301 14.580 45.144 40.673 1.00 53.67 C +ANISOU 2418 CG1 VAL A 301 9361 5144 5885 -189 187 -395 C +ATOM 2419 CG2 VAL A 301 12.179 45.764 40.186 1.00 54.54 C +ANISOU 2419 CG2 VAL A 301 9414 5048 6260 64 234 -507 C +ATOM 2420 N ASP A 302 16.279 47.746 40.325 1.00 68.20 N +ANISOU 2420 N ASP A 302 11432 6738 7741 -407 34 -315 N +ATOM 2421 CA ASP A 302 17.729 47.852 40.200 1.00 74.34 C +ANISOU 2421 CA ASP A 302 12224 7585 8436 -570 -23 -228 C +ATOM 2422 C ASP A 302 18.325 46.451 40.052 1.00 76.22 C +ANISOU 2422 C ASP A 302 12327 8038 8592 -589 -10 -166 C +ATOM 2423 O ASP A 302 17.930 45.530 40.778 1.00 76.70 O +ANISOU 2423 O ASP A 302 12342 8186 8611 -539 40 -230 O +ATOM 2424 CB ASP A 302 18.309 48.549 41.447 1.00 77.58 C +ANISOU 2424 CB ASP A 302 12751 7929 8797 -688 -32 -318 C +ATOM 2425 CG ASP A 302 19.672 49.176 41.191 1.00 81.19 C +ANISOU 2425 CG ASP A 302 13244 8380 9224 -861 -113 -234 C +ATOM 2426 OD1 ASP A 302 20.509 48.507 40.542 1.00 82.92 O +ANISOU 2426 OD1 ASP A 302 13352 8743 9409 -918 -134 -128 O +ATOM 2427 OD2 ASP A 302 19.907 50.339 41.642 1.00 82.44 O +ANISOU 2427 OD2 ASP A 302 13537 8386 9398 -944 -148 -281 O +ATOM 2428 N VAL A 303 19.253 46.294 39.107 1.00 77.31 N +ANISOU 2428 N VAL A 303 12407 8254 8712 -664 -47 -47 N +ATOM 2429 CA VAL A 303 19.995 45.040 38.931 1.00 76.82 C +ANISOU 2429 CA VAL A 303 12210 8383 8592 -690 -37 4 C +ATOM 2430 C VAL A 303 21.461 45.352 38.585 1.00 80.06 C +ANISOU 2430 C VAL A 303 12589 8841 8987 -849 -77 81 C +ATOM 2431 O VAL A 303 21.746 46.340 37.912 1.00 81.28 O +ANISOU 2431 O VAL A 303 12810 8903 9168 -922 -98 135 O +ATOM 2432 CB VAL A 303 19.340 44.146 37.852 1.00 75.73 C +ANISOU 2432 CB VAL A 303 11984 8320 8468 -573 -3 60 C +ATOM 2433 CG1 VAL A 303 17.937 43.727 38.268 1.00 74.41 C +ANISOU 2433 CG1 VAL A 303 11817 8122 8333 -427 37 -21 C +ATOM 2434 CG2 VAL A 303 19.269 44.857 36.510 1.00 77.19 C +ANISOU 2434 CG2 VAL A 303 12215 8427 8685 -584 -27 152 C +ATOM 2435 N SER A 304 22.391 44.538 39.073 1.00 84.75 N +ANISOU 2435 N SER A 304 13081 9571 9548 -910 -93 84 N +ATOM 2436 CA SER A 304 23.823 44.745 38.763 1.00 88.48 C +ANISOU 2436 CA SER A 304 13481 10102 10035 -1060 -125 147 C +ATOM 2437 C SER A 304 24.657 43.457 38.818 1.00 91.07 C +ANISOU 2437 C SER A 304 13633 10604 10364 -1064 -128 167 C +ATOM 2438 O SER A 304 25.827 43.456 38.426 1.00 93.08 O +ANISOU 2438 O SER A 304 13782 10927 10658 -1171 -137 214 O +ATOM 2439 CB SER A 304 24.425 45.803 39.690 1.00 87.65 C +ANISOU 2439 CB SER A 304 13471 9900 9928 -1196 -195 106 C +ATOM 2440 OG SER A 304 23.826 47.057 39.453 1.00 84.45 O +ANISOU 2440 OG SER A 304 13221 9322 9543 -1203 -193 97 O +ATOM 2441 N ASP A 311 32.275 37.300 44.363 1.00 82.03 N +ANISOU 2441 N ASP A 311 11512 10045 9610 -1327 -1106 199 N +ATOM 2442 CA ASP A 311 33.126 36.222 44.876 1.00 83.98 C +ANISOU 2442 CA ASP A 311 11603 10338 9966 -1298 -1286 223 C +ATOM 2443 C ASP A 311 32.316 35.022 45.425 1.00 79.86 C +ANISOU 2443 C ASP A 311 11191 9811 9341 -1173 -1329 230 C +ATOM 2444 O ASP A 311 31.432 35.170 46.274 1.00 79.40 O +ANISOU 2444 O ASP A 311 11380 9689 9098 -1189 -1351 212 O +ATOM 2445 CB ASP A 311 34.076 36.752 45.952 1.00 88.89 C +ANISOU 2445 CB ASP A 311 12235 10918 10619 -1451 -1521 229 C +ATOM 2446 CG ASP A 311 35.201 35.764 46.303 1.00 93.65 C +ANISOU 2446 CG ASP A 311 12616 11566 11400 -1430 -1730 261 C +ATOM 2447 OD1 ASP A 311 35.386 34.727 45.609 1.00 94.94 O +ANISOU 2447 OD1 ASP A 311 12584 11793 11693 -1297 -1673 271 O +ATOM 2448 OD2 ASP A 311 35.910 36.040 47.299 1.00 97.72 O +ANISOU 2448 OD2 ASP A 311 13157 12041 11931 -1547 -1966 274 O +ATOM 2449 N CYS A 312 32.668 33.832 44.945 1.00 76.43 N +ANISOU 2449 N CYS A 312 10568 9437 9032 -1057 -1336 250 N +ATOM 2450 CA CYS A 312 31.819 32.629 45.075 1.00 73.84 C +ANISOU 2450 CA CYS A 312 10319 9110 8626 -921 -1320 258 C +ATOM 2451 C CYS A 312 31.842 31.929 46.449 1.00 73.98 C +ANISOU 2451 C CYS A 312 10471 9076 8561 -939 -1553 287 C +ATOM 2452 O CYS A 312 30.802 31.611 47.019 1.00 69.85 O +ANISOU 2452 O CYS A 312 10167 8513 7857 -917 -1531 282 O +ATOM 2453 CB CYS A 312 32.199 31.620 43.976 1.00 72.06 C +ANISOU 2453 CB CYS A 312 9850 8957 8571 -790 -1233 261 C +ATOM 2454 SG CYS A 312 30.962 30.346 43.606 1.00 69.39 S +ANISOU 2454 SG CYS A 312 9600 8624 8139 -622 -1121 260 S +ATOM 2455 N LEU A 313 33.037 31.652 46.953 1.00 77.52 N +ANISOU 2455 N LEU A 313 10781 9522 9148 -983 -1779 317 N +ATOM 2456 CA LEU A 313 33.207 30.853 48.158 1.00 80.82 C +ANISOU 2456 CA LEU A 313 11309 9886 9511 -996 -2035 361 C +ATOM 2457 C LEU A 313 33.693 31.787 49.232 1.00 85.05 C +ANISOU 2457 C LEU A 313 11978 10367 9968 -1171 -2224 365 C +ATOM 2458 O LEU A 313 34.810 31.657 49.707 1.00 87.36 O +ANISOU 2458 O LEU A 313 12147 10647 10396 -1226 -2467 399 O +ATOM 2459 CB LEU A 313 34.227 29.723 47.938 1.00 81.96 C +ANISOU 2459 CB LEU A 313 11189 10052 9897 -898 -2192 397 C +ATOM 2460 CG LEU A 313 33.834 28.700 46.861 1.00 80.54 C +ANISOU 2460 CG LEU A 313 10873 9919 9807 -721 -2014 383 C +ATOM 2461 CD1 LEU A 313 35.022 27.910 46.311 1.00 81.45 C +ANISOU 2461 CD1 LEU A 313 10654 10066 10225 -627 -2099 385 C +ATOM 2462 CD2 LEU A 313 32.763 27.782 47.418 1.00 79.50 C +ANISOU 2462 CD2 LEU A 313 10977 9739 9491 -659 -2032 410 C +ATOM 2463 N ALA A 314 32.855 32.750 49.592 1.00 89.07 N +ANISOU 2463 N ALA A 314 12734 10838 10270 -1260 -2112 324 N +ATOM 2464 CA ALA A 314 33.120 33.639 50.723 1.00 94.74 C +ANISOU 2464 CA ALA A 314 13648 11488 10861 -1435 -2276 314 C +ATOM 2465 C ALA A 314 32.646 32.945 52.014 1.00101.25 C +ANISOU 2465 C ALA A 314 14746 12248 11474 -1472 -2440 340 C +ATOM 2466 O ALA A 314 31.580 32.319 52.032 1.00101.58 O +ANISOU 2466 O ALA A 314 14925 12287 11382 -1393 -2308 333 O +ATOM 2467 CB ALA A 314 32.413 34.973 50.529 1.00 92.96 C +ANISOU 2467 CB ALA A 314 13572 11234 10514 -1507 -2073 246 C +ATOM 2468 N ASN A 315 33.457 33.028 53.067 1.00110.83 N +ANISOU 2468 N ASN A 315 16038 13411 12661 -1602 -2733 375 N +ATOM 2469 CA ASN A 315 33.112 32.444 54.372 1.00117.75 C +ANISOU 2469 CA ASN A 315 17211 14216 13311 -1674 -2917 408 C +ATOM 2470 C ASN A 315 32.011 33.269 55.058 1.00123.28 C +ANISOU 2470 C ASN A 315 18262 14864 13712 -1783 -2760 332 C +ATOM 2471 O ASN A 315 31.019 32.693 55.526 1.00123.61 O +ANISOU 2471 O ASN A 315 18526 14882 13555 -1767 -2675 324 O +ATOM 2472 CB ASN A 315 34.362 32.302 55.262 1.00120.02 C +ANISOU 2472 CB ASN A 315 17479 14457 13664 -1786 -3306 474 C +ATOM 2473 CG ASN A 315 34.160 31.342 56.426 1.00121.22 C +ANISOU 2473 CG ASN A 315 17893 14538 13626 -1830 -3537 541 C +ATOM 2474 OD1 ASN A 315 33.286 30.471 56.402 1.00119.41 O +ANISOU 2474 OD1 ASN A 315 17774 14308 13289 -1742 -3423 556 O +ATOM 2475 ND2 ASN A 315 34.989 31.491 57.451 1.00123.45 N +ANISOU 2475 ND2 ASN A 315 18283 14755 13865 -1978 -3875 588 N +ATOM 2476 N PRO A 316 32.175 34.617 55.113 1.00129.52 N +ANISOU 2476 N PRO A 316 19101 15630 14479 -1898 -2710 268 N +ATOM 2477 CA PRO A 316 31.034 35.504 55.384 1.00130.26 C +ANISOU 2477 CA PRO A 316 19456 15678 14358 -1952 -2476 168 C +ATOM 2478 C PRO A 316 30.331 35.829 54.054 1.00130.10 C +ANISOU 2478 C PRO A 316 19267 15709 14455 -1808 -2161 125 C +ATOM 2479 O PRO A 316 30.488 36.940 53.509 1.00130.80 O +ANISOU 2479 O PRO A 316 19286 15787 14622 -1839 -2063 81 O +ATOM 2480 CB PRO A 316 31.694 36.743 55.988 1.00131.81 C +ANISOU 2480 CB PRO A 316 19757 15813 14512 -2135 -2605 128 C +ATOM 2481 CG PRO A 316 33.029 36.811 55.327 1.00131.68 C +ANISOU 2481 CG PRO A 316 19409 15845 14778 -2127 -2764 189 C +ATOM 2482 CD PRO A 316 33.428 35.397 54.981 1.00131.37 C +ANISOU 2482 CD PRO A 316 19157 15866 14891 -1991 -2874 279 C +ATOM 2483 N ALA A 317 29.603 34.827 53.542 1.00128.36 N +ANISOU 2483 N ALA A 317 18987 15534 14246 -1659 -2029 145 N +ATOM 2484 CA ALA A 317 29.021 34.850 52.187 1.00124.89 C +ANISOU 2484 CA ALA A 317 18363 15152 13937 -1507 -1774 126 C +ATOM 2485 C ALA A 317 27.953 35.922 52.121 1.00122.46 C +ANISOU 2485 C ALA A 317 18215 14796 13517 -1525 -1544 30 C +ATOM 2486 O ALA A 317 26.952 35.834 52.831 1.00121.19 O +ANISOU 2486 O ALA A 317 18283 14593 13169 -1545 -1454 -24 O +ATOM 2487 CB ALA A 317 28.421 33.493 51.826 1.00122.59 C +ANISOU 2487 CB ALA A 317 18015 14906 13654 -1363 -1709 164 C +ATOM 2488 N VAL A 318 28.167 36.922 51.264 1.00122.24 N +ANISOU 2488 N VAL A 318 18066 14767 13612 -1520 -1447 8 N +ATOM 2489 CA VAL A 318 27.252 38.064 51.124 1.00122.11 C +ANISOU 2489 CA VAL A 318 18184 14683 13528 -1530 -1252 -80 C +ATOM 2490 C VAL A 318 26.103 37.718 50.169 1.00120.59 C +ANISOU 2490 C VAL A 318 17924 14520 13372 -1368 -1022 -97 C +ATOM 2491 O VAL A 318 26.351 37.405 48.995 1.00118.49 O +ANISOU 2491 O VAL A 318 17441 14320 13260 -1271 -973 -44 O +ATOM 2492 CB VAL A 318 28.000 39.313 50.596 1.00121.24 C +ANISOU 2492 CB VAL A 318 17987 14541 13534 -1606 -1267 -85 C +ATOM 2493 CG1 VAL A 318 27.032 40.466 50.334 1.00120.20 C +ANISOU 2493 CG1 VAL A 318 17984 14323 13361 -1595 -1074 -170 C +ATOM 2494 CG2 VAL A 318 29.101 39.723 51.566 1.00122.16 C +ANISOU 2494 CG2 VAL A 318 18173 14622 13620 -1781 -1504 -76 C +ATOM 2495 N PRO A 319 24.841 37.769 50.660 1.00118.72 N +ANISOU 2495 N PRO A 319 17872 14236 12998 -1344 -879 -175 N +ATOM 2496 CA PRO A 319 23.713 37.433 49.779 1.00112.60 C +ANISOU 2496 CA PRO A 319 17024 13486 12272 -1193 -679 -192 C +ATOM 2497 C PRO A 319 23.484 38.514 48.705 1.00104.31 C +ANISOU 2497 C PRO A 319 15890 12399 11343 -1143 -561 -212 C +ATOM 2498 O PRO A 319 23.808 39.692 48.933 1.00103.64 O +ANISOU 2498 O PRO A 319 15884 12237 11256 -1234 -583 -250 O +ATOM 2499 CB PRO A 319 22.520 37.331 50.741 1.00116.36 C +ANISOU 2499 CB PRO A 319 17719 13912 12580 -1209 -565 -284 C +ATOM 2500 CG PRO A 319 22.906 38.135 51.941 1.00118.15 C +ANISOU 2500 CG PRO A 319 18160 14060 12671 -1372 -651 -344 C +ATOM 2501 CD PRO A 319 24.406 38.080 52.038 1.00120.24 C +ANISOU 2501 CD PRO A 319 18342 14353 12988 -1460 -890 -256 C +ATOM 2502 N TRP A 320 22.981 38.098 47.538 1.00 92.92 N +ANISOU 2502 N TRP A 320 14301 11004 10000 -1009 -453 -179 N +ATOM 2503 CA TRP A 320 22.740 39.020 46.441 1.00 84.88 C +ANISOU 2503 CA TRP A 320 13217 9948 9087 -961 -359 -179 C +ATOM 2504 C TRP A 320 21.359 39.638 46.650 1.00 78.91 C +ANISOU 2504 C TRP A 320 12591 9098 8291 -909 -214 -276 C +ATOM 2505 O TRP A 320 20.329 38.951 46.793 1.00 74.20 O +ANISOU 2505 O TRP A 320 12013 8518 7658 -826 -120 -313 O +ATOM 2506 CB TRP A 320 22.870 38.327 45.089 1.00 84.69 C +ANISOU 2506 CB TRP A 320 12994 10009 9173 -857 -322 -101 C +ATOM 2507 CG TRP A 320 22.744 39.250 43.914 1.00 84.29 C +ANISOU 2507 CG TRP A 320 12895 9919 9212 -830 -248 -83 C +ATOM 2508 CD1 TRP A 320 22.956 40.610 43.888 1.00 85.46 C +ANISOU 2508 CD1 TRP A 320 13120 9970 9380 -909 -253 -103 C +ATOM 2509 CD2 TRP A 320 22.418 38.876 42.575 1.00 81.40 C +ANISOU 2509 CD2 TRP A 320 12411 9597 8917 -729 -172 -33 C +ATOM 2510 NE1 TRP A 320 22.757 41.099 42.617 1.00 83.50 N +ANISOU 2510 NE1 TRP A 320 12814 9701 9210 -864 -188 -61 N +ATOM 2511 CE2 TRP A 320 22.425 40.059 41.793 1.00 81.44 C +ANISOU 2511 CE2 TRP A 320 12438 9528 8974 -756 -138 -18 C +ATOM 2512 CE3 TRP A 320 22.109 37.663 41.957 1.00 79.07 C +ANISOU 2512 CE3 TRP A 320 12011 9390 8640 -626 -134 0 C +ATOM 2513 CZ2 TRP A 320 22.142 40.054 40.438 1.00 78.40 C +ANISOU 2513 CZ2 TRP A 320 11985 9157 8643 -691 -75 33 C +ATOM 2514 CZ3 TRP A 320 21.824 37.667 40.600 1.00 77.48 C +ANISOU 2514 CZ3 TRP A 320 11736 9205 8495 -559 -64 41 C +ATOM 2515 CH2 TRP A 320 21.844 38.854 39.861 1.00 76.64 C +ANISOU 2515 CH2 TRP A 320 11665 9027 8425 -595 -38 60 C +ATOM 2516 N SER A 321 21.357 40.959 46.705 1.00 75.95 N +ANISOU 2516 N SER A 321 12303 8617 7936 -962 -199 -324 N +ATOM 2517 CA SER A 321 20.168 41.737 47.066 1.00 73.00 C +ANISOU 2517 CA SER A 321 12063 8128 7546 -923 -74 -438 C +ATOM 2518 C SER A 321 19.042 41.548 46.016 1.00 67.68 C +ANISOU 2518 C SER A 321 11290 7452 6974 -763 43 -434 C +ATOM 2519 O SER A 321 17.898 41.183 46.343 1.00 65.92 O +ANISOU 2519 O SER A 321 11096 7216 6734 -689 153 -508 O +ATOM 2520 CB SER A 321 20.603 43.206 47.226 1.00 74.52 C +ANISOU 2520 CB SER A 321 12359 8196 7760 -1017 -111 -477 C +ATOM 2521 OG SER A 321 19.513 44.113 47.294 1.00 76.94 O +ANISOU 2521 OG SER A 321 12762 8369 8103 -956 6 -582 O +ATOM 2522 N GLN A 322 19.414 41.737 44.755 1.00 61.98 N +ANISOU 2522 N GLN A 322 10447 6747 6353 -724 15 -343 N +ATOM 2523 CA GLN A 322 18.472 41.774 43.650 1.00 58.58 C +ANISOU 2523 CA GLN A 322 9942 6292 6020 -593 89 -326 C +ATOM 2524 C GLN A 322 18.062 40.383 43.158 1.00 52.87 C +ANISOU 2524 C GLN A 322 9099 5689 5299 -499 120 -282 C +ATOM 2525 O GLN A 322 17.104 40.252 42.397 1.00 49.84 O +ANISOU 2525 O GLN A 322 8663 5290 4984 -387 178 -281 O +ATOM 2526 CB GLN A 322 19.089 42.577 42.495 1.00 61.09 C +ANISOU 2526 CB GLN A 322 10219 6573 6418 -617 40 -241 C +ATOM 2527 CG GLN A 322 19.538 43.996 42.871 1.00 64.87 C +ANISOU 2527 CG GLN A 322 10820 6920 6906 -719 0 -274 C +ATOM 2528 CD GLN A 322 21.052 44.129 43.049 1.00 66.95 C +ANISOU 2528 CD GLN A 322 11062 7236 7137 -871 -99 -215 C +ATOM 2529 OE1 GLN A 322 21.829 43.974 42.077 1.00 68.10 O +ANISOU 2529 OE1 GLN A 322 11098 7450 7326 -901 -128 -116 O +ATOM 2530 NE2 GLN A 322 21.481 44.424 44.281 1.00 65.77 N +ANISOU 2530 NE2 GLN A 322 11018 7056 6915 -975 -148 -280 N +ATOM 2531 N GLY A 323 18.784 39.347 43.585 1.00 49.28 N +ANISOU 2531 N GLY A 323 8604 5343 4776 -543 66 -244 N +ATOM 2532 CA GLY A 323 18.469 37.957 43.219 1.00 45.59 C +ANISOU 2532 CA GLY A 323 8036 4980 4304 -463 86 -205 C +ATOM 2533 C GLY A 323 17.036 37.536 43.486 1.00 43.36 C +ANISOU 2533 C GLY A 323 7780 4678 4017 -376 192 -276 C +ATOM 2534 O GLY A 323 16.444 36.782 42.719 1.00 40.79 O +ANISOU 2534 O GLY A 323 7362 4399 3735 -284 227 -247 O +ATOM 2535 N ILE A 324 16.472 38.058 44.559 1.00 42.88 N +ANISOU 2535 N ILE A 324 7843 4543 3905 -414 250 -378 N +ATOM 2536 CA ILE A 324 15.120 37.710 44.961 1.00 43.02 C +ANISOU 2536 CA ILE A 324 7881 4541 3923 -352 374 -466 C +ATOM 2537 C ILE A 324 14.095 38.239 43.957 1.00 41.47 C +ANISOU 2537 C ILE A 324 7603 4280 3872 -229 435 -486 C +ATOM 2538 O ILE A 324 13.142 37.546 43.624 1.00 40.49 O +ANISOU 2538 O ILE A 324 7401 4186 3796 -145 498 -499 O +ATOM 2539 CB ILE A 324 14.849 38.217 46.397 1.00 45.98 C +ANISOU 2539 CB ILE A 324 8423 4848 4198 -440 441 -587 C +ATOM 2540 CG1 ILE A 324 13.552 37.663 46.962 1.00 46.72 C +ANISOU 2540 CG1 ILE A 324 8535 4943 4274 -404 591 -684 C +ATOM 2541 CG2 ILE A 324 14.857 39.745 46.466 1.00 48.36 C +ANISOU 2541 CG2 ILE A 324 8800 5019 4554 -458 453 -653 C +ATOM 2542 CD1 ILE A 324 13.693 36.217 47.404 1.00 46.97 C +ANISOU 2542 CD1 ILE A 324 8574 5080 4191 -445 572 -634 C +ATOM 2543 N ASP A 325 14.308 39.441 43.438 1.00 41.65 N +ANISOU 2543 N ASP A 325 7643 4210 3970 -223 399 -478 N +ATOM 2544 CA ASP A 325 13.384 39.996 42.443 1.00 41.72 C +ANISOU 2544 CA ASP A 325 7587 4139 4123 -108 420 -481 C +ATOM 2545 C ASP A 325 13.525 39.264 41.124 1.00 39.06 C +ANISOU 2545 C ASP A 325 7135 3884 3820 -50 360 -363 C +ATOM 2546 O ASP A 325 12.540 39.011 40.462 1.00 38.65 O +ANISOU 2546 O ASP A 325 7010 3820 3855 50 382 -365 O +ATOM 2547 CB ASP A 325 13.579 41.494 42.255 1.00 44.19 C +ANISOU 2547 CB ASP A 325 7975 4310 4503 -124 383 -497 C +ATOM 2548 CG ASP A 325 13.194 42.294 43.510 1.00 47.29 C +ANISOU 2548 CG ASP A 325 8489 4596 4883 -160 463 -642 C +ATOM 2549 OD1 ASP A 325 12.551 41.746 44.446 1.00 48.72 O +ANISOU 2549 OD1 ASP A 325 8689 4805 5015 -161 570 -741 O +ATOM 2550 OD2 ASP A 325 13.531 43.507 43.570 1.00 49.89 O +ANISOU 2550 OD2 ASP A 325 8907 4803 5245 -198 428 -664 O +ATOM 2551 N ILE A 326 14.741 38.896 40.768 1.00 36.89 N +ANISOU 2551 N ILE A 326 6842 3694 3480 -118 288 -269 N +ATOM 2552 CA ILE A 326 14.953 38.141 39.565 1.00 35.97 C +ANISOU 2552 CA ILE A 326 6628 3660 3378 -76 251 -172 C +ATOM 2553 C ILE A 326 14.216 36.796 39.653 1.00 35.42 C +ANISOU 2553 C ILE A 326 6489 3671 3294 -10 296 -189 C +ATOM 2554 O ILE A 326 13.512 36.442 38.718 1.00 33.22 O +ANISOU 2554 O ILE A 326 6147 3400 3074 71 297 -162 O +ATOM 2555 CB ILE A 326 16.453 37.982 39.246 1.00 35.21 C +ANISOU 2555 CB ILE A 326 6508 3639 3230 -165 188 -88 C +ATOM 2556 CG1 ILE A 326 17.050 39.374 38.958 1.00 36.19 C +ANISOU 2556 CG1 ILE A 326 6696 3671 3380 -236 149 -64 C +ATOM 2557 CG2 ILE A 326 16.658 37.028 38.084 1.00 33.76 C +ANISOU 2557 CG2 ILE A 326 6226 3549 3049 -122 179 -11 C +ATOM 2558 CD1 ILE A 326 18.558 39.421 38.899 1.00 36.18 C +ANISOU 2558 CD1 ILE A 326 6669 3732 3344 -350 99 -5 C +ATOM 2559 N GLU A 327 14.368 36.077 40.784 1.00 36.59 N +ANISOU 2559 N GLU A 327 6667 3872 3362 -56 323 -231 N +ATOM 2560 CA GLU A 327 13.658 34.810 41.027 1.00 36.72 C +ANISOU 2560 CA GLU A 327 6642 3954 3357 -15 370 -250 C +ATOM 2561 C GLU A 327 12.167 35.017 40.918 1.00 36.92 C +ANISOU 2561 C GLU A 327 6638 3918 3471 67 452 -323 C +ATOM 2562 O GLU A 327 11.477 34.306 40.213 1.00 36.75 O +ANISOU 2562 O GLU A 327 6533 3929 3500 138 459 -303 O +ATOM 2563 CB GLU A 327 13.954 34.241 42.431 1.00 38.39 C +ANISOU 2563 CB GLU A 327 6934 4197 3454 -99 386 -290 C +ATOM 2564 CG GLU A 327 13.362 32.854 42.713 1.00 39.21 C +ANISOU 2564 CG GLU A 327 7014 4365 3518 -79 425 -294 C +ATOM 2565 CD GLU A 327 13.380 32.397 44.182 1.00 41.26 C +ANISOU 2565 CD GLU A 327 7394 4631 3650 -174 454 -341 C +ATOM 2566 OE1 GLU A 327 13.295 31.151 44.423 1.00 40.76 O +ANISOU 2566 OE1 GLU A 327 7330 4624 3531 -184 446 -312 O +ATOM 2567 OE2 GLU A 327 13.467 33.248 45.107 1.00 45.73 O +ANISOU 2567 OE2 GLU A 327 8073 5140 4160 -247 483 -407 O +ATOM 2568 N ARG A 328 11.660 35.992 41.637 1.00 37.97 N +ANISOU 2568 N ARG A 328 6833 3957 3635 57 513 -417 N +ATOM 2569 CA ARG A 328 10.240 36.225 41.664 1.00 39.32 C +ANISOU 2569 CA ARG A 328 6955 4063 3919 138 601 -507 C +ATOM 2570 C ARG A 328 9.723 36.570 40.238 1.00 37.37 C +ANISOU 2570 C ARG A 328 6615 3771 3810 243 532 -452 C +ATOM 2571 O ARG A 328 8.630 36.169 39.863 1.00 36.38 O +ANISOU 2571 O ARG A 328 6398 3642 3783 323 560 -480 O +ATOM 2572 CB ARG A 328 9.940 37.309 42.715 1.00 43.02 C +ANISOU 2572 CB ARG A 328 7518 4427 4400 105 686 -631 C +ATOM 2573 CG ARG A 328 8.540 37.876 42.742 1.00 47.35 C +ANISOU 2573 CG ARG A 328 8003 4877 5110 198 782 -747 C +ATOM 2574 CD ARG A 328 8.522 38.978 43.812 1.00 53.07 C +ANISOU 2574 CD ARG A 328 8845 5495 5824 151 866 -873 C +ATOM 2575 NE ARG A 328 7.704 40.157 43.506 1.00 58.35 N +ANISOU 2575 NE ARG A 328 9474 6012 6684 251 888 -955 N +ATOM 2576 CZ ARG A 328 7.945 41.046 42.522 1.00 61.99 C +ANISOU 2576 CZ ARG A 328 9925 6381 7246 310 761 -882 C +ATOM 2577 NH1 ARG A 328 8.978 40.910 41.667 1.00 62.11 N +ANISOU 2577 NH1 ARG A 328 9960 6451 7187 272 621 -728 N +ATOM 2578 NH2 ARG A 328 7.128 42.092 42.379 1.00 63.96 N +ANISOU 2578 NH2 ARG A 328 10147 6474 7681 406 777 -967 N +ATOM 2579 N ALA A 329 10.512 37.293 39.452 1.00 36.32 N +ANISOU 2579 N ALA A 329 6514 3604 3681 232 435 -370 N +ATOM 2580 CA ALA A 329 10.118 37.673 38.089 1.00 36.50 C +ANISOU 2580 CA ALA A 329 6490 3575 3803 309 351 -302 C +ATOM 2581 C ALA A 329 10.047 36.470 37.126 1.00 35.40 C +ANISOU 2581 C ALA A 329 6274 3539 3636 340 310 -222 C +ATOM 2582 O ALA A 329 9.118 36.333 36.354 1.00 34.81 O +ANISOU 2582 O ALA A 329 6136 3434 3653 420 274 -213 O +ATOM 2583 CB ALA A 329 11.053 38.724 37.546 1.00 36.50 C +ANISOU 2583 CB ALA A 329 6569 3513 3785 260 271 -230 C +ATOM 2584 N LEU A 330 11.036 35.599 37.206 1.00 34.93 N +ANISOU 2584 N LEU A 330 6221 3592 3458 275 310 -172 N +ATOM 2585 CA LEU A 330 11.047 34.367 36.434 1.00 34.21 C +ANISOU 2585 CA LEU A 330 6069 3597 3332 299 287 -114 C +ATOM 2586 C LEU A 330 9.855 33.477 36.790 1.00 34.69 C +ANISOU 2586 C LEU A 330 6062 3679 3439 352 341 -176 C +ATOM 2587 O LEU A 330 9.250 32.885 35.921 1.00 34.36 O +ANISOU 2587 O LEU A 330 5963 3656 3436 405 306 -147 O +ATOM 2588 CB LEU A 330 12.343 33.600 36.674 1.00 33.33 C +ANISOU 2588 CB LEU A 330 5968 3588 3109 227 285 -70 C +ATOM 2589 CG LEU A 330 13.624 34.219 36.123 1.00 33.64 C +ANISOU 2589 CG LEU A 330 6037 3633 3109 165 239 -2 C +ATOM 2590 CD1 LEU A 330 14.863 33.602 36.762 1.00 33.42 C +ANISOU 2590 CD1 LEU A 330 5999 3688 3008 95 237 11 C +ATOM 2591 CD2 LEU A 330 13.686 34.065 34.622 1.00 33.11 C +ANISOU 2591 CD2 LEU A 330 5953 3584 3043 189 201 71 C +ATOM 2592 N LYS A 331 9.527 33.377 38.070 1.00 35.24 N +ANISOU 2592 N LYS A 331 6148 3745 3495 324 429 -262 N +ATOM 2593 CA LYS A 331 8.419 32.530 38.497 1.00 35.94 C +ANISOU 2593 CA LYS A 331 6174 3856 3622 350 503 -326 C +ATOM 2594 C LYS A 331 7.047 33.049 38.128 1.00 37.70 C +ANISOU 2594 C LYS A 331 6312 3999 4012 437 518 -385 C +ATOM 2595 O LYS A 331 6.122 32.258 37.991 1.00 38.67 O +ANISOU 2595 O LYS A 331 6349 4148 4193 470 545 -411 O +ATOM 2596 CB LYS A 331 8.482 32.264 40.004 1.00 35.82 C +ANISOU 2596 CB LYS A 331 6225 3861 3523 272 606 -401 C +ATOM 2597 CG LYS A 331 9.424 31.127 40.298 1.00 35.04 C +ANISOU 2597 CG LYS A 331 6170 3855 3288 207 574 -338 C +ATOM 2598 CD LYS A 331 9.869 31.044 41.736 1.00 35.43 C +ANISOU 2598 CD LYS A 331 6330 3912 3219 107 624 -381 C +ATOM 2599 CE LYS A 331 11.104 30.182 41.807 1.00 35.09 C +ANISOU 2599 CE LYS A 331 6323 3939 3069 58 533 -294 C +ATOM 2600 NZ LYS A 331 11.205 29.450 43.103 1.00 36.20 N +ANISOU 2600 NZ LYS A 331 6566 4100 3087 -32 563 -316 N +ATOM 2601 N MET A 332 6.896 34.353 37.947 1.00 39.87 N +ANISOU 2601 N MET A 332 6602 4167 4378 476 489 -407 N +ATOM 2602 CA MET A 332 5.576 34.893 37.664 1.00 42.43 C +ANISOU 2602 CA MET A 332 6830 4396 4893 571 490 -472 C +ATOM 2603 C MET A 332 5.241 35.035 36.164 1.00 40.54 C +ANISOU 2603 C MET A 332 6544 4118 4741 646 337 -382 C +ATOM 2604 O MET A 332 4.140 35.435 35.831 1.00 40.05 O +ANISOU 2604 O MET A 332 6389 3970 4855 733 301 -423 O +ATOM 2605 CB MET A 332 5.363 36.209 38.414 1.00 47.68 C +ANISOU 2605 CB MET A 332 7532 4941 5642 586 550 -570 C +ATOM 2606 CG MET A 332 6.078 37.406 37.845 1.00 51.54 C +ANISOU 2606 CG MET A 332 8109 5337 6137 590 442 -506 C +ATOM 2607 SD MET A 332 5.801 38.844 38.889 1.00 61.49 S +ANISOU 2607 SD MET A 332 9424 6446 7492 603 528 -643 S +ATOM 2608 CE MET A 332 4.060 39.195 38.595 1.00 64.34 C +ANISOU 2608 CE MET A 332 9618 6691 8137 754 538 -743 C +ATOM 2609 N VAL A 333 6.143 34.650 35.264 1.00 38.64 N +ANISOU 2609 N VAL A 333 6363 3938 4381 610 246 -264 N +ATOM 2610 CA VAL A 333 5.871 34.826 33.856 1.00 39.14 C +ANISOU 2610 CA VAL A 333 6419 3959 4491 659 103 -177 C +ATOM 2611 C VAL A 333 4.742 33.895 33.411 1.00 39.01 C +ANISOU 2611 C VAL A 333 6288 3971 4561 714 73 -193 C +ATOM 2612 O VAL A 333 4.607 32.791 33.918 1.00 37.71 O +ANISOU 2612 O VAL A 333 6077 3899 4351 686 157 -229 O +ATOM 2613 CB VAL A 333 7.103 34.617 32.937 1.00 38.42 C +ANISOU 2613 CB VAL A 333 6427 3930 4241 594 37 -58 C +ATOM 2614 CG1 VAL A 333 8.317 35.368 33.437 1.00 38.03 C +ANISOU 2614 CG1 VAL A 333 6471 3873 4104 519 75 -43 C +ATOM 2615 CG2 VAL A 333 7.446 33.158 32.809 1.00 38.19 C +ANISOU 2615 CG2 VAL A 333 6373 4033 4102 560 73 -37 C +ATOM 2616 N GLN A 334 3.916 34.383 32.490 1.00 39.71 N +ANISOU 2616 N GLN A 334 6338 3967 4783 788 -58 -165 N +ATOM 2617 CA GLN A 334 2.990 33.555 31.746 1.00 40.27 C +ANISOU 2617 CA GLN A 334 6318 4059 4922 829 -140 -150 C +ATOM 2618 C GLN A 334 3.275 33.820 30.271 1.00 39.58 C +ANISOU 2618 C GLN A 334 6329 3933 4774 827 -320 -24 C +ATOM 2619 O GLN A 334 2.994 34.886 29.783 1.00 40.71 O +ANISOU 2619 O GLN A 334 6504 3952 5010 872 -438 8 O +ATOM 2620 CB GLN A 334 1.528 33.861 32.091 1.00 42.26 C +ANISOU 2620 CB GLN A 334 6408 4225 5421 919 -142 -248 C +ATOM 2621 CG GLN A 334 0.551 33.071 31.236 1.00 43.83 C +ANISOU 2621 CG GLN A 334 6505 4436 5710 956 -258 -226 C +ATOM 2622 CD GLN A 334 -0.910 33.283 31.587 1.00 47.16 C +ANISOU 2622 CD GLN A 334 6729 4783 6406 1043 -255 -332 C +ATOM 2623 OE1 GLN A 334 -1.289 34.282 32.226 1.00 50.05 O +ANISOU 2623 OE1 GLN A 334 7037 5050 6929 1103 -203 -417 O +ATOM 2624 NE2 GLN A 334 -1.756 32.349 31.140 1.00 48.73 N +ANISOU 2624 NE2 GLN A 334 6813 5022 6679 1051 -313 -336 N +ATOM 2625 N VAL A 335 3.865 32.851 29.588 1.00 38.21 N +ANISOU 2625 N VAL A 335 6218 3860 4438 769 -336 41 N +ATOM 2626 CA VAL A 335 4.153 32.979 28.166 1.00 38.10 C +ANISOU 2626 CA VAL A 335 6320 3822 4333 745 -486 153 C +ATOM 2627 C VAL A 335 3.750 31.716 27.405 1.00 36.90 C +ANISOU 2627 C VAL A 335 6150 3742 4128 734 -540 173 C +ATOM 2628 O VAL A 335 3.708 30.609 27.975 1.00 35.83 O +ANISOU 2628 O VAL A 335 5942 3701 3969 721 -435 118 O +ATOM 2629 CB VAL A 335 5.649 33.243 27.886 1.00 38.05 C +ANISOU 2629 CB VAL A 335 6461 3862 4134 656 -437 222 C +ATOM 2630 CG1 VAL A 335 6.062 34.567 28.450 1.00 39.11 C +ANISOU 2630 CG1 VAL A 335 6637 3909 4311 652 -415 217 C +ATOM 2631 CG2 VAL A 335 6.533 32.169 28.480 1.00 36.95 C +ANISOU 2631 CG2 VAL A 335 6306 3862 3871 602 -288 190 C +ATOM 2632 N GLN A 336 3.457 31.911 26.125 1.00 36.46 N +ANISOU 2632 N GLN A 336 6176 3629 4047 733 -713 256 N +ATOM 2633 CA GLN A 336 3.177 30.832 25.204 1.00 36.10 C +ANISOU 2633 CA GLN A 336 6158 3637 3921 706 -789 285 C +ATOM 2634 C GLN A 336 4.459 30.478 24.461 1.00 35.18 C +ANISOU 2634 C GLN A 336 6209 3596 3562 613 -741 349 C +ATOM 2635 O GLN A 336 5.131 31.342 23.906 1.00 35.59 O +ANISOU 2635 O GLN A 336 6394 3603 3523 568 -776 420 O +ATOM 2636 CB GLN A 336 2.042 31.194 24.250 1.00 37.11 C +ANISOU 2636 CB GLN A 336 6285 3655 4160 750 -1020 333 C +ATOM 2637 CG GLN A 336 0.759 31.603 24.951 1.00 38.03 C +ANISOU 2637 CG GLN A 336 6204 3688 4555 852 -1064 258 C +ATOM 2638 CD GLN A 336 0.278 30.572 25.969 1.00 37.49 C +ANISOU 2638 CD GLN A 336 5962 3712 4570 865 -909 146 C +ATOM 2639 OE1 GLN A 336 0.006 29.407 25.630 1.00 37.00 O +ANISOU 2639 OE1 GLN A 336 5879 3721 4458 833 -922 140 O +ATOM 2640 NE2 GLN A 336 0.181 30.996 27.240 1.00 37.29 N +ANISOU 2640 NE2 GLN A 336 5828 3679 4660 901 -758 56 N +ATOM 2641 N GLY A 337 4.807 29.195 24.489 1.00 33.95 N +ANISOU 2641 N GLY A 337 6041 3549 3310 581 -649 316 N +ATOM 2642 CA GLY A 337 6.058 28.742 23.912 1.00 33.55 C +ANISOU 2642 CA GLY A 337 6114 3575 3056 503 -567 347 C +ATOM 2643 C GLY A 337 5.820 27.494 23.125 1.00 33.69 C +ANISOU 2643 C GLY A 337 6169 3643 2988 480 -600 340 C +ATOM 2644 O GLY A 337 4.676 27.065 22.938 1.00 33.78 O +ANISOU 2644 O GLY A 337 6121 3623 3090 515 -710 324 O +ATOM 2645 N MET A 338 6.907 26.886 22.690 1.00 34.01 N +ANISOU 2645 N MET A 338 6297 3760 2865 420 -499 340 N +ATOM 2646 CA MET A 338 6.804 25.645 21.937 1.00 34.92 C +ANISOU 2646 CA MET A 338 6464 3919 2884 395 -510 319 C +ATOM 2647 C MET A 338 6.204 24.507 22.786 1.00 33.50 C +ANISOU 2647 C MET A 338 6145 3775 2809 444 -472 245 C +ATOM 2648 O MET A 338 5.688 23.538 22.236 1.00 34.22 O +ANISOU 2648 O MET A 338 6258 3873 2870 434 -527 225 O +ATOM 2649 CB MET A 338 8.170 25.242 21.426 1.00 36.15 C +ANISOU 2649 CB MET A 338 6719 4146 2869 330 -375 313 C +ATOM 2650 CG MET A 338 8.757 26.181 20.384 1.00 38.54 C +ANISOU 2650 CG MET A 338 7190 4420 3031 249 -398 385 C +ATOM 2651 SD MET A 338 10.386 25.601 19.819 1.00 42.20 S +ANISOU 2651 SD MET A 338 7736 4980 3315 168 -194 349 S +ATOM 2652 CE MET A 338 9.872 24.454 18.546 1.00 41.85 C +ANISOU 2652 CE MET A 338 7830 4939 3132 132 -255 324 C +ATOM 2653 N THR A 339 6.268 24.626 24.110 1.00 31.31 N +ANISOU 2653 N THR A 339 5742 3514 2640 483 -381 206 N +ATOM 2654 CA THR A 339 5.704 23.602 24.994 1.00 30.14 C +ANISOU 2654 CA THR A 339 5478 3393 2578 510 -335 143 C +ATOM 2655 C THR A 339 4.425 24.078 25.696 1.00 30.22 C +ANISOU 2655 C THR A 339 5361 3351 2770 554 -389 118 C +ATOM 2656 O THR A 339 4.216 23.767 26.849 1.00 29.54 O +ANISOU 2656 O THR A 339 5178 3284 2761 566 -298 67 O +ATOM 2657 CB THR A 339 6.731 23.072 26.026 1.00 28.25 C +ANISOU 2657 CB THR A 339 5205 3217 2309 506 -184 107 C +ATOM 2658 OG1 THR A 339 7.137 24.093 26.947 1.00 27.51 O +ANISOU 2658 OG1 THR A 339 5073 3115 2263 515 -127 111 O +ATOM 2659 CG2 THR A 339 7.939 22.553 25.304 1.00 28.34 C +ANISOU 2659 CG2 THR A 339 5309 3276 2180 475 -127 115 C +ATOM 2660 N GLY A 340 3.585 24.824 24.982 1.00 30.70 N +ANISOU 2660 N GLY A 340 5426 3337 2899 574 -536 153 N +ATOM 2661 CA GLY A 340 2.290 25.216 25.495 1.00 30.94 C +ANISOU 2661 CA GLY A 340 5312 3310 3133 624 -596 118 C +ATOM 2662 C GLY A 340 2.403 26.419 26.399 1.00 30.90 C +ANISOU 2662 C GLY A 340 5253 3264 3224 662 -533 101 C +ATOM 2663 O GLY A 340 3.399 27.149 26.377 1.00 30.93 O +ANISOU 2663 O GLY A 340 5349 3265 3136 645 -494 139 O +ATOM 2664 N ASN A 341 1.359 26.620 27.202 1.00 31.11 N +ANISOU 2664 N ASN A 341 5124 3254 3441 707 -515 36 N +ATOM 2665 CA ASN A 341 1.332 27.608 28.237 1.00 31.01 C +ANISOU 2665 CA ASN A 341 5048 3202 3532 742 -426 -10 C +ATOM 2666 C ASN A 341 2.433 27.326 29.246 1.00 29.88 C +ANISOU 2666 C ASN A 341 4954 3135 3264 695 -249 -34 C +ATOM 2667 O ASN A 341 2.572 26.184 29.699 1.00 29.30 O +ANISOU 2667 O ASN A 341 4867 3134 3129 656 -165 -61 O +ATOM 2668 CB ASN A 341 -0.032 27.571 28.905 1.00 32.21 C +ANISOU 2668 CB ASN A 341 5012 3318 3906 785 -405 -99 C +ATOM 2669 CG ASN A 341 -0.154 28.568 30.057 1.00 32.94 C +ANISOU 2669 CG ASN A 341 5036 3364 4114 821 -286 -173 C +ATOM 2670 OD1 ASN A 341 -0.144 29.788 29.851 1.00 33.40 O +ANISOU 2670 OD1 ASN A 341 5114 3331 4245 872 -356 -156 O +ATOM 2671 ND2 ASN A 341 -0.264 28.034 31.294 1.00 32.57 N +ANISOU 2671 ND2 ASN A 341 4926 3373 4074 785 -104 -259 N +ATOM 2672 N ILE A 342 3.212 28.357 29.592 1.00 29.87 N +ANISOU 2672 N ILE A 342 5015 3107 3228 694 -210 -19 N +ATOM 2673 CA ILE A 342 4.329 28.234 30.532 1.00 29.12 C +ANISOU 2673 CA ILE A 342 4971 3073 3020 647 -73 -34 C +ATOM 2674 C ILE A 342 4.084 29.116 31.756 1.00 30.00 C +ANISOU 2674 C ILE A 342 5033 3137 3225 661 18 -106 C +ATOM 2675 O ILE A 342 4.066 30.343 31.636 1.00 31.92 O +ANISOU 2675 O ILE A 342 5296 3298 3532 692 -24 -98 O +ATOM 2676 CB ILE A 342 5.650 28.651 29.890 1.00 28.63 C +ANISOU 2676 CB ILE A 342 5034 3027 2815 610 -96 41 C +ATOM 2677 CG1 ILE A 342 5.993 27.743 28.725 1.00 28.89 C +ANISOU 2677 CG1 ILE A 342 5130 3110 2735 585 -153 95 C +ATOM 2678 CG2 ILE A 342 6.791 28.566 30.873 1.00 27.82 C +ANISOU 2678 CG2 ILE A 342 4963 2982 2626 563 19 25 C +ATOM 2679 CD1 ILE A 342 6.917 28.382 27.688 1.00 29.33 C +ANISOU 2679 CD1 ILE A 342 5308 3155 2678 549 -202 172 C +ATOM 2680 N GLN A 343 3.867 28.498 32.904 1.00 29.62 N +ANISOU 2680 N GLN A 343 4938 3133 3182 633 143 -177 N +ATOM 2681 CA GLN A 343 3.769 29.196 34.193 1.00 30.34 C +ANISOU 2681 CA GLN A 343 5014 3193 3319 623 261 -258 C +ATOM 2682 C GLN A 343 4.395 28.333 35.262 1.00 29.52 C +ANISOU 2682 C GLN A 343 4961 3167 3087 545 375 -279 C +ATOM 2683 O GLN A 343 4.488 27.111 35.113 1.00 29.17 O +ANISOU 2683 O GLN A 343 4919 3186 2974 516 372 -253 O +ATOM 2684 CB GLN A 343 2.325 29.418 34.659 1.00 31.61 C +ANISOU 2684 CB GLN A 343 5039 3300 3671 665 314 -358 C +ATOM 2685 CG GLN A 343 1.465 30.249 33.768 1.00 33.09 C +ANISOU 2685 CG GLN A 343 5145 3389 4035 755 189 -353 C +ATOM 2686 CD GLN A 343 0.012 30.198 34.204 1.00 35.01 C +ANISOU 2686 CD GLN A 343 5214 3595 4492 797 247 -461 C +ATOM 2687 OE1 GLN A 343 -0.803 29.505 33.593 1.00 35.79 O +ANISOU 2687 OE1 GLN A 343 5214 3706 4676 815 175 -454 O +ATOM 2688 NE2 GLN A 343 -0.313 30.901 35.289 1.00 36.41 N +ANISOU 2688 NE2 GLN A 343 5349 3726 4756 805 387 -571 N +ATOM 2689 N PHE A 344 4.751 28.958 36.361 1.00 29.38 N +ANISOU 2689 N PHE A 344 4990 3132 3039 510 466 -329 N +ATOM 2690 CA PHE A 344 5.407 28.269 37.426 1.00 29.15 C +ANISOU 2690 CA PHE A 344 5035 3162 2877 428 548 -339 C +ATOM 2691 C PHE A 344 4.714 28.534 38.771 1.00 30.92 C +ANISOU 2691 C PHE A 344 5256 3361 3130 385 694 -450 C +ATOM 2692 O PHE A 344 4.040 29.531 38.957 1.00 31.36 O +ANISOU 2692 O PHE A 344 5262 3346 3305 425 740 -524 O +ATOM 2693 CB PHE A 344 6.867 28.707 37.515 1.00 27.94 C +ANISOU 2693 CB PHE A 344 4984 3023 2606 393 506 -281 C +ATOM 2694 CG PHE A 344 7.617 28.575 36.239 1.00 26.80 C +ANISOU 2694 CG PHE A 344 4848 2904 2431 421 397 -188 C +ATOM 2695 CD1 PHE A 344 8.215 27.369 35.891 1.00 26.06 C +ANISOU 2695 CD1 PHE A 344 4766 2880 2254 404 368 -137 C +ATOM 2696 CD2 PHE A 344 7.753 29.655 35.395 1.00 26.84 C +ANISOU 2696 CD2 PHE A 344 4860 2855 2482 458 330 -154 C +ATOM 2697 CE1 PHE A 344 8.900 27.238 34.709 1.00 25.42 C +ANISOU 2697 CE1 PHE A 344 4694 2822 2139 424 295 -69 C +ATOM 2698 CE2 PHE A 344 8.439 29.548 34.206 1.00 26.44 C +ANISOU 2698 CE2 PHE A 344 4834 2828 2382 464 250 -73 C +ATOM 2699 CZ PHE A 344 9.013 28.342 33.858 1.00 25.93 C +ANISOU 2699 CZ PHE A 344 4774 2842 2236 446 243 -37 C +ATOM 2700 N ASP A 345 4.897 27.595 39.697 1.00 32.23 N +ANISOU 2700 N ASP A 345 5483 3578 3182 300 768 -461 N +ATOM 2701 CA ASP A 345 4.470 27.750 41.056 1.00 34.25 C +ANISOU 2701 CA ASP A 345 5785 3820 3405 226 917 -558 C +ATOM 2702 C ASP A 345 5.661 28.265 41.837 1.00 34.30 C +ANISOU 2702 C ASP A 345 5938 3823 3269 163 907 -541 C +ATOM 2703 O ASP A 345 6.725 28.501 41.264 1.00 32.30 O +ANISOU 2703 O ASP A 345 5717 3579 2974 185 789 -458 O +ATOM 2704 CB ASP A 345 3.981 26.420 41.627 1.00 35.60 C +ANISOU 2704 CB ASP A 345 5969 4040 3515 147 993 -569 C +ATOM 2705 CG ASP A 345 5.116 25.441 41.920 1.00 36.02 C +ANISOU 2705 CG ASP A 345 6151 4143 3392 80 919 -477 C +ATOM 2706 OD1 ASP A 345 6.295 25.829 41.820 1.00 37.76 O +ANISOU 2706 OD1 ASP A 345 6439 4365 3540 88 828 -417 O +ATOM 2707 OD2 ASP A 345 4.850 24.265 42.249 1.00 37.27 O +ANISOU 2707 OD2 ASP A 345 6337 4330 3491 18 946 -461 O +ATOM 2708 N THR A 346 5.483 28.396 43.154 1.00 35.89 N +ANISOU 2708 N THR A 346 6232 4013 3392 72 1034 -622 N +ATOM 2709 CA THR A 346 6.488 29.023 43.983 1.00 36.62 C +ANISOU 2709 CA THR A 346 6470 4088 3355 3 1021 -622 C +ATOM 2710 C THR A 346 7.807 28.237 44.129 1.00 35.78 C +ANISOU 2710 C THR A 346 6464 4034 3096 -53 895 -510 C +ATOM 2711 O THR A 346 8.833 28.822 44.445 1.00 35.03 O +ANISOU 2711 O THR A 346 6453 3926 2929 -87 827 -483 O +ATOM 2712 CB THR A 346 5.920 29.356 45.355 1.00 38.54 C +ANISOU 2712 CB THR A 346 6807 4299 3534 -91 1192 -745 C +ATOM 2713 OG1 THR A 346 6.819 30.283 45.957 1.00 40.52 O +ANISOU 2713 OG1 THR A 346 7188 4513 3695 -139 1162 -757 O +ATOM 2714 CG2 THR A 346 5.762 28.083 46.261 1.00 38.83 C +ANISOU 2714 CG2 THR A 346 6945 4386 3420 -214 1260 -738 C +ATOM 2715 N TYR A 347 7.791 26.936 43.878 1.00 36.14 N +ANISOU 2715 N TYR A 347 6492 4129 3108 -60 855 -448 N +ATOM 2716 CA TYR A 347 9.031 26.154 43.852 1.00 37.01 C +ANISOU 2716 CA TYR A 347 6667 4276 3119 -86 719 -343 C +ATOM 2717 C TYR A 347 9.636 25.977 42.472 1.00 35.77 C +ANISOU 2717 C TYR A 347 6403 4145 3040 12 602 -263 C +ATOM 2718 O TYR A 347 10.475 25.116 42.273 1.00 36.48 O +ANISOU 2718 O TYR A 347 6507 4266 3087 12 507 -189 O +ATOM 2719 CB TYR A 347 8.826 24.798 44.526 1.00 39.03 C +ANISOU 2719 CB TYR A 347 7000 4552 3275 -164 734 -319 C +ATOM 2720 CG TYR A 347 8.321 24.969 45.930 1.00 42.29 C +ANISOU 2720 CG TYR A 347 7549 4940 3576 -288 859 -396 C +ATOM 2721 CD1 TYR A 347 9.117 25.587 46.904 1.00 44.50 C +ANISOU 2721 CD1 TYR A 347 7977 5198 3731 -371 831 -403 C +ATOM 2722 CD2 TYR A 347 7.031 24.574 46.294 1.00 44.86 C +ANISOU 2722 CD2 TYR A 347 7860 5264 3918 -334 1017 -471 C +ATOM 2723 CE1 TYR A 347 8.654 25.781 48.200 1.00 46.57 C +ANISOU 2723 CE1 TYR A 347 8393 5435 3866 -500 957 -483 C +ATOM 2724 CE2 TYR A 347 6.572 24.756 47.607 1.00 46.94 C +ANISOU 2724 CE2 TYR A 347 8263 5508 4064 -465 1162 -554 C +ATOM 2725 CZ TYR A 347 7.388 25.375 48.532 1.00 47.91 C +ANISOU 2725 CZ TYR A 347 8551 5606 4044 -546 1133 -560 C +ATOM 2726 OH TYR A 347 6.943 25.600 49.802 1.00 53.25 O +ANISOU 2726 OH TYR A 347 9387 6259 4584 -685 1283 -651 O +ATOM 2727 N GLY A 348 9.228 26.817 41.524 1.00 35.36 N +ANISOU 2727 N GLY A 348 6256 4074 3105 92 609 -281 N +ATOM 2728 CA GLY A 348 9.757 26.795 40.187 1.00 33.72 C +ANISOU 2728 CA GLY A 348 5974 3886 2952 168 515 -212 C +ATOM 2729 C GLY A 348 9.306 25.631 39.344 1.00 32.97 C +ANISOU 2729 C GLY A 348 5814 3824 2889 212 490 -181 C +ATOM 2730 O GLY A 348 9.947 25.338 38.341 1.00 33.69 O +ANISOU 2730 O GLY A 348 5872 3940 2987 256 416 -123 O +ATOM 2731 N ARG A 349 8.218 24.973 39.718 1.00 32.35 N +ANISOU 2731 N ARG A 349 5720 3743 2829 194 559 -224 N +ATOM 2732 CA ARG A 349 7.678 23.875 38.937 1.00 32.26 C +ANISOU 2732 CA ARG A 349 5649 3752 2853 227 533 -201 C +ATOM 2733 C ARG A 349 6.634 24.369 37.933 1.00 29.81 C +ANISOU 2733 C ARG A 349 5233 3420 2673 297 530 -228 C +ATOM 2734 O ARG A 349 5.907 25.319 38.193 1.00 29.45 O +ANISOU 2734 O ARG A 349 5146 3334 2709 310 586 -289 O +ATOM 2735 CB ARG A 349 7.052 22.825 39.846 1.00 35.20 C +ANISOU 2735 CB ARG A 349 6063 4131 3180 153 600 -227 C +ATOM 2736 CG ARG A 349 8.071 22.038 40.638 1.00 38.51 C +ANISOU 2736 CG ARG A 349 6598 4561 3472 90 555 -176 C +ATOM 2737 CD ARG A 349 7.399 20.993 41.517 1.00 43.05 C +ANISOU 2737 CD ARG A 349 7239 5129 3987 1 617 -191 C +ATOM 2738 NE ARG A 349 8.376 20.373 42.420 1.00 46.78 N +ANISOU 2738 NE ARG A 349 7849 5593 4331 -66 553 -136 N +ATOM 2739 CZ ARG A 349 8.429 20.575 43.741 1.00 51.96 C +ANISOU 2739 CZ ARG A 349 8634 6231 4875 -173 602 -156 C +ATOM 2740 NH1 ARG A 349 7.526 21.338 44.369 1.00 53.22 N +ANISOU 2740 NH1 ARG A 349 8802 6383 5034 -228 748 -244 N +ATOM 2741 NH2 ARG A 349 9.370 19.957 44.468 1.00 55.01 N +ANISOU 2741 NH2 ARG A 349 9151 6601 5150 -231 502 -90 N +ATOM 2742 N ARG A 350 6.560 23.715 36.789 1.00 27.35 N +ANISOU 2742 N ARG A 350 4880 3125 2386 342 456 -186 N +ATOM 2743 CA ARG A 350 5.575 24.078 35.787 1.00 26.99 C +ANISOU 2743 CA ARG A 350 4746 3052 2455 401 418 -199 C +ATOM 2744 C ARG A 350 4.185 23.858 36.366 1.00 27.37 C +ANISOU 2744 C ARG A 350 4715 3082 2600 381 498 -274 C +ATOM 2745 O ARG A 350 3.926 22.856 37.017 1.00 27.35 O +ANISOU 2745 O ARG A 350 4730 3103 2557 320 556 -290 O +ATOM 2746 CB ARG A 350 5.723 23.260 34.508 1.00 26.06 C +ANISOU 2746 CB ARG A 350 4625 2957 2320 432 324 -145 C +ATOM 2747 CG ARG A 350 6.982 23.542 33.703 1.00 25.52 C +ANISOU 2747 CG ARG A 350 4614 2906 2175 452 263 -84 C +ATOM 2748 CD ARG A 350 6.871 24.780 32.829 1.00 25.87 C +ANISOU 2748 CD ARG A 350 4651 2911 2265 491 206 -63 C +ATOM 2749 NE ARG A 350 5.862 24.726 31.758 1.00 26.17 N +ANISOU 2749 NE ARG A 350 4648 2920 2373 528 125 -56 N +ATOM 2750 CZ ARG A 350 6.082 24.329 30.493 1.00 25.97 C +ANISOU 2750 CZ ARG A 350 4665 2906 2295 536 46 -11 C +ATOM 2751 NH1 ARG A 350 7.267 23.899 30.090 1.00 25.20 N +ANISOU 2751 NH1 ARG A 350 4636 2853 2084 517 60 21 N +ATOM 2752 NH2 ARG A 350 5.087 24.369 29.622 1.00 26.34 N +ANISOU 2752 NH2 ARG A 350 4684 2916 2407 562 -47 -4 N +ATOM 2753 N THR A 351 3.295 24.790 36.125 1.00 27.66 N +ANISOU 2753 N THR A 351 4662 3071 2775 429 500 -321 N +ATOM 2754 CA THR A 351 1.944 24.623 36.503 1.00 29.18 C +ANISOU 2754 CA THR A 351 4742 3245 3097 420 575 -400 C +ATOM 2755 C THR A 351 1.058 25.055 35.336 1.00 30.33 C +ANISOU 2755 C THR A 351 4770 3346 3406 503 463 -398 C +ATOM 2756 O THR A 351 1.491 25.822 34.486 1.00 30.22 O +ANISOU 2756 O THR A 351 4785 3299 3396 561 353 -345 O +ATOM 2757 CB THR A 351 1.656 25.412 37.808 1.00 30.24 C +ANISOU 2757 CB THR A 351 4876 3353 3261 386 727 -495 C +ATOM 2758 OG1 THR A 351 0.479 24.894 38.403 1.00 31.83 O +ANISOU 2758 OG1 THR A 351 4983 3559 3551 341 846 -580 O +ATOM 2759 CG2 THR A 351 1.432 26.861 37.578 1.00 30.72 C +ANISOU 2759 CG2 THR A 351 4885 3341 3444 464 706 -532 C +ATOM 2760 N ASN A 352 -0.158 24.534 35.285 1.00 32.05 N +ANISOU 2760 N ASN A 352 4861 3559 3755 497 482 -449 N +ATOM 2761 CA ASN A 352 -1.105 24.844 34.222 1.00 33.83 C +ANISOU 2761 CA ASN A 352 4962 3736 4155 570 352 -448 C +ATOM 2762 C ASN A 352 -0.521 24.488 32.825 1.00 33.05 C +ANISOU 2762 C ASN A 352 4947 3646 3961 595 171 -340 C +ATOM 2763 O ASN A 352 -0.609 25.241 31.865 1.00 33.80 O +ANISOU 2763 O ASN A 352 5040 3689 4113 658 31 -298 O +ATOM 2764 CB ASN A 352 -1.512 26.313 34.327 1.00 35.77 C +ANISOU 2764 CB ASN A 352 5133 3900 4558 649 348 -498 C +ATOM 2765 CG ASN A 352 -2.864 26.604 33.711 1.00 38.45 C +ANISOU 2765 CG ASN A 352 5286 4174 5146 718 255 -539 C +ATOM 2766 OD1 ASN A 352 -3.562 25.706 33.233 1.00 39.73 O +ANISOU 2766 OD1 ASN A 352 5367 4361 5367 697 197 -534 O +ATOM 2767 ND2 ASN A 352 -3.231 27.894 33.689 1.00 40.81 N +ANISOU 2767 ND2 ASN A 352 5517 4380 5607 804 223 -579 N +ATOM 2768 N TYR A 353 0.075 23.314 32.747 1.00 32.26 N +ANISOU 2768 N TYR A 353 4936 3607 3713 538 179 -300 N +ATOM 2769 CA TYR A 353 0.604 22.743 31.520 1.00 31.80 C +ANISOU 2769 CA TYR A 353 4963 3564 3552 544 47 -221 C +ATOM 2770 C TYR A 353 -0.332 21.670 30.972 1.00 32.86 C +ANISOU 2770 C TYR A 353 5034 3704 3747 519 -17 -232 C +ATOM 2771 O TYR A 353 -1.284 21.259 31.617 1.00 34.08 O +ANISOU 2771 O TYR A 353 5076 3860 4012 486 51 -294 O +ATOM 2772 CB TYR A 353 1.992 22.136 31.759 1.00 30.35 C +ANISOU 2772 CB TYR A 353 4917 3434 3178 507 98 -179 C +ATOM 2773 CG TYR A 353 2.057 21.048 32.839 1.00 29.79 C +ANISOU 2773 CG TYR A 353 4863 3400 3054 439 211 -209 C +ATOM 2774 CD1 TYR A 353 2.010 19.721 32.504 1.00 29.53 C +ANISOU 2774 CD1 TYR A 353 4861 3386 2973 405 182 -195 C +ATOM 2775 CD2 TYR A 353 2.201 21.380 34.177 1.00 29.51 C +ANISOU 2775 CD2 TYR A 353 4834 3370 3006 402 337 -249 C +ATOM 2776 CE1 TYR A 353 2.105 18.737 33.471 1.00 29.56 C +ANISOU 2776 CE1 TYR A 353 4901 3406 2921 337 267 -209 C +ATOM 2777 CE2 TYR A 353 2.275 20.430 35.160 1.00 29.55 C +ANISOU 2777 CE2 TYR A 353 4884 3398 2944 326 425 -265 C +ATOM 2778 CZ TYR A 353 2.231 19.100 34.813 1.00 29.69 C +ANISOU 2778 CZ TYR A 353 4932 3428 2919 294 386 -239 C +ATOM 2779 OH TYR A 353 2.318 18.142 35.793 1.00 29.86 O +ANISOU 2779 OH TYR A 353 5018 3458 2869 212 459 -243 O +ATOM 2780 N THR A 354 -0.036 21.228 29.763 1.00 33.17 N +ANISOU 2780 N THR A 354 5151 3745 3705 525 -146 -174 N +ATOM 2781 CA THR A 354 -0.795 20.178 29.099 1.00 34.02 C +ANISOU 2781 CA THR A 354 5229 3852 3844 494 -232 -178 C +ATOM 2782 C THR A 354 0.178 19.134 28.598 1.00 32.87 C +ANISOU 2782 C THR A 354 5232 3740 3514 462 -240 -140 C +ATOM 2783 O THR A 354 1.222 19.462 28.076 1.00 31.97 O +ANISOU 2783 O THR A 354 5231 3638 3278 483 -256 -97 O +ATOM 2784 CB THR A 354 -1.622 20.702 27.916 1.00 35.28 C +ANISOU 2784 CB THR A 354 5342 3957 4106 533 -421 -154 C +ATOM 2785 OG1 THR A 354 -2.514 21.721 28.373 1.00 37.45 O +ANISOU 2785 OG1 THR A 354 5461 4184 4584 581 -422 -196 O +ATOM 2786 CG2 THR A 354 -2.448 19.592 27.328 1.00 36.18 C +ANISOU 2786 CG2 THR A 354 5420 4069 4258 487 -514 -165 C +ATOM 2787 N ILE A 355 -0.187 17.882 28.799 1.00 33.10 N +ANISOU 2787 N ILE A 355 5254 3782 3540 408 -217 -165 N +ATOM 2788 CA ILE A 355 0.553 16.763 28.266 1.00 33.40 C +ANISOU 2788 CA ILE A 355 5420 3834 3435 384 -236 -144 C +ATOM 2789 C ILE A 355 -0.334 16.065 27.252 1.00 35.36 C +ANISOU 2789 C ILE A 355 5660 4054 3718 355 -368 -150 C +ATOM 2790 O ILE A 355 -1.484 15.758 27.532 1.00 36.59 O +ANISOU 2790 O ILE A 355 5699 4195 4007 318 -386 -184 O +ATOM 2791 CB ILE A 355 1.003 15.819 29.376 1.00 32.15 C +ANISOU 2791 CB ILE A 355 5293 3693 3227 340 -113 -161 C +ATOM 2792 CG1 ILE A 355 2.015 16.569 30.232 1.00 31.43 C +ANISOU 2792 CG1 ILE A 355 5233 3626 3082 366 -16 -147 C +ATOM 2793 CG2 ILE A 355 1.606 14.569 28.769 1.00 31.73 C +ANISOU 2793 CG2 ILE A 355 5357 3633 3065 325 -148 -152 C +ATOM 2794 CD1 ILE A 355 2.718 15.741 31.291 1.00 31.21 C +ANISOU 2794 CD1 ILE A 355 5268 3608 2981 328 73 -146 C +ATOM 2795 N ASP A 356 0.186 15.861 26.056 1.00 37.18 N +ANISOU 2795 N ASP A 356 6016 4279 3832 364 -460 -123 N +ATOM 2796 CA ASP A 356 -0.613 15.214 25.021 1.00 39.83 C +ANISOU 2796 CA ASP A 356 6372 4582 4177 328 -604 -128 C +ATOM 2797 C ASP A 356 -0.304 13.723 25.112 1.00 37.89 C +ANISOU 2797 C ASP A 356 6206 4335 3853 280 -557 -157 C +ATOM 2798 O ASP A 356 0.845 13.342 25.321 1.00 35.23 O +ANISOU 2798 O ASP A 356 5966 4016 3404 298 -464 -156 O +ATOM 2799 CB ASP A 356 -0.286 15.790 23.634 1.00 42.32 C +ANISOU 2799 CB ASP A 356 6811 4881 4388 345 -733 -86 C +ATOM 2800 CG ASP A 356 -0.633 17.289 23.505 1.00 46.64 C +ANISOU 2800 CG ASP A 356 7293 5406 5021 391 -807 -48 C +ATOM 2801 OD1 ASP A 356 -1.835 17.643 23.575 1.00 50.94 O +ANISOU 2801 OD1 ASP A 356 7698 5915 5739 398 -906 -56 O +ATOM 2802 OD2 ASP A 356 0.293 18.138 23.298 1.00 50.37 O +ANISOU 2802 OD2 ASP A 356 7851 5888 5398 421 -773 -10 O +ATOM 2803 N VAL A 357 -1.330 12.894 24.973 1.00 38.37 N +ANISOU 2803 N VAL A 357 6219 4368 3991 221 -628 -183 N +ATOM 2804 CA VAL A 357 -1.167 11.457 25.115 1.00 38.75 C +ANISOU 2804 CA VAL A 357 6343 4397 3984 169 -592 -211 C +ATOM 2805 C VAL A 357 -1.364 10.791 23.771 1.00 39.99 C +ANISOU 2805 C VAL A 357 6614 4516 4063 137 -732 -223 C +ATOM 2806 O VAL A 357 -2.373 11.020 23.133 1.00 41.53 O +ANISOU 2806 O VAL A 357 6753 4691 4333 107 -875 -220 O +ATOM 2807 CB VAL A 357 -2.182 10.886 26.116 1.00 38.98 C +ANISOU 2807 CB VAL A 357 6243 4415 4152 98 -544 -238 C +ATOM 2808 CG1 VAL A 357 -1.966 9.402 26.295 1.00 38.96 C +ANISOU 2808 CG1 VAL A 357 6339 4376 4086 38 -515 -257 C +ATOM 2809 CG2 VAL A 357 -2.070 11.596 27.462 1.00 38.21 C +ANISOU 2809 CG2 VAL A 357 6048 4353 4117 114 -397 -236 C +ATOM 2810 N TYR A 358 -0.412 9.957 23.363 1.00 40.30 N +ANISOU 2810 N TYR A 358 6811 4540 3960 142 -694 -241 N +ATOM 2811 CA TYR A 358 -0.430 9.309 22.049 1.00 42.39 C +ANISOU 2811 CA TYR A 358 7222 4767 4117 109 -804 -266 C +ATOM 2812 C TYR A 358 -0.590 7.809 22.135 1.00 43.92 C +ANISOU 2812 C TYR A 358 7479 4906 4302 54 -801 -313 C +ATOM 2813 O TYR A 358 0.118 7.166 22.879 1.00 42.74 O +ANISOU 2813 O TYR A 358 7356 4744 4138 75 -685 -326 O +ATOM 2814 CB TYR A 358 0.857 9.637 21.274 1.00 42.20 C +ANISOU 2814 CB TYR A 358 7349 4761 3923 160 -753 -268 C +ATOM 2815 CG TYR A 358 0.856 11.046 20.738 1.00 42.44 C +ANISOU 2815 CG TYR A 358 7371 4822 3928 185 -811 -218 C +ATOM 2816 CD1 TYR A 358 1.116 12.104 21.585 1.00 41.94 C +ANISOU 2816 CD1 TYR A 358 7196 4800 3939 237 -735 -179 C +ATOM 2817 CD2 TYR A 358 0.549 11.323 19.410 1.00 43.41 C +ANISOU 2817 CD2 TYR A 358 7614 4925 3955 147 -955 -206 C +ATOM 2818 CE1 TYR A 358 1.097 13.404 21.129 1.00 42.56 C +ANISOU 2818 CE1 TYR A 358 7273 4890 4005 258 -796 -130 C +ATOM 2819 CE2 TYR A 358 0.532 12.626 18.937 1.00 44.02 C +ANISOU 2819 CE2 TYR A 358 7702 5015 4009 163 -1025 -147 C +ATOM 2820 CZ TYR A 358 0.800 13.666 19.807 1.00 43.85 C +ANISOU 2820 CZ TYR A 358 7558 5027 4076 222 -944 -109 C +ATOM 2821 OH TYR A 358 0.796 14.989 19.422 1.00 44.63 O +ANISOU 2821 OH TYR A 358 7667 5124 4166 241 -1013 -49 O +ATOM 2822 N GLU A 359 -1.533 7.267 21.376 1.00 47.99 N +ANISOU 2822 N GLU A 359 8021 5378 4832 -19 -944 -334 N +ATOM 2823 CA GLU A 359 -1.726 5.822 21.278 1.00 52.18 C +ANISOU 2823 CA GLU A 359 8638 5842 5346 -84 -963 -382 C +ATOM 2824 C GLU A 359 -1.334 5.360 19.895 1.00 53.89 C +ANISOU 2824 C GLU A 359 9057 6018 5400 -97 -1040 -425 C +ATOM 2825 O GLU A 359 -1.838 5.882 18.930 1.00 56.01 O +ANISOU 2825 O GLU A 359 9361 6290 5627 -128 -1180 -414 O +ATOM 2826 CB GLU A 359 -3.188 5.447 21.551 1.00 55.25 C +ANISOU 2826 CB GLU A 359 8896 6205 5890 -183 -1063 -383 C +ATOM 2827 CG GLU A 359 -3.574 5.513 23.033 1.00 56.41 C +ANISOU 2827 CG GLU A 359 8872 6377 6184 -200 -944 -364 C +ATOM 2828 CD GLU A 359 -5.058 5.256 23.301 1.00 60.27 C +ANISOU 2828 CD GLU A 359 9199 6851 6847 -306 -1019 -374 C +ATOM 2829 OE1 GLU A 359 -5.859 5.081 22.334 1.00 61.99 O +ANISOU 2829 OE1 GLU A 359 9417 7040 7095 -362 -1193 -390 O +ATOM 2830 OE2 GLU A 359 -5.422 5.237 24.508 1.00 61.85 O +ANISOU 2830 OE2 GLU A 359 9272 7070 7157 -342 -900 -369 O +ATOM 2831 N MET A 360 -0.429 4.403 19.787 1.00 55.95 N +ANISOU 2831 N MET A 360 9458 6234 5566 -75 -954 -479 N +ATOM 2832 CA MET A 360 0.022 3.932 18.473 1.00 59.94 C +ANISOU 2832 CA MET A 360 10170 6698 5904 -89 -993 -541 C +ATOM 2833 C MET A 360 -0.327 2.468 18.280 1.00 59.47 C +ANISOU 2833 C MET A 360 10213 6541 5842 -156 -1040 -607 C +ATOM 2834 O MET A 360 -0.750 1.820 19.240 1.00 58.63 O +ANISOU 2834 O MET A 360 10018 6398 5858 -184 -1023 -596 O +ATOM 2835 CB MET A 360 1.527 4.153 18.302 1.00 62.00 C +ANISOU 2835 CB MET A 360 10519 6984 6052 3 -835 -571 C +ATOM 2836 CG MET A 360 2.057 5.478 18.843 1.00 63.73 C +ANISOU 2836 CG MET A 360 10621 7292 6299 73 -753 -504 C +ATOM 2837 SD MET A 360 2.258 6.951 17.776 1.00 71.57 S +ANISOU 2837 SD MET A 360 11676 8351 7164 73 -797 -463 S +ATOM 2838 CE MET A 360 3.196 6.307 16.370 1.00 72.35 C +ANISOU 2838 CE MET A 360 12032 8417 7039 54 -737 -560 C +ATOM 2839 N SER A 365 -1.702 5.530 15.071 1.00 76.90 N +ANISOU 2839 N SER A 365 12568 8849 7800 -264 -1492 -494 N +ATOM 2840 CA SER A 365 -0.819 6.573 15.623 1.00 76.93 C +ANISOU 2840 CA SER A 365 12495 8925 7807 -167 -1341 -448 C +ATOM 2841 C SER A 365 -1.568 7.896 15.964 1.00 75.00 C +ANISOU 2841 C SER A 365 12074 8722 7698 -148 -1446 -355 C +ATOM 2842 O SER A 365 -1.096 9.003 15.652 1.00 74.76 O +ANISOU 2842 O SER A 365 12077 8729 7598 -112 -1435 -306 O +ATOM 2843 CB SER A 365 0.367 6.818 14.672 1.00 77.85 C +ANISOU 2843 CB SER A 365 12825 9057 7696 -153 -1245 -481 C +ATOM 2844 OG SER A 365 1.161 7.928 15.067 1.00 78.81 O +ANISOU 2844 OG SER A 365 12879 9247 7817 -79 -1125 -430 O +ATOM 2845 N ARG A 366 -2.716 7.763 16.633 1.00 71.52 N +ANISOU 2845 N ARG A 366 11442 8269 7461 -174 -1535 -337 N +ATOM 2846 CA ARG A 366 -3.537 8.918 16.998 1.00 69.18 C +ANISOU 2846 CA ARG A 366 10954 7998 7334 -149 -1633 -270 C +ATOM 2847 C ARG A 366 -3.185 9.513 18.358 1.00 61.71 C +ANISOU 2847 C ARG A 366 9825 7105 6516 -67 -1451 -249 C +ATOM 2848 O ARG A 366 -2.780 8.826 19.293 1.00 58.32 O +ANISOU 2848 O ARG A 366 9354 6685 6117 -54 -1290 -281 O +ATOM 2849 CB ARG A 366 -5.037 8.583 16.939 1.00 74.44 C +ANISOU 2849 CB ARG A 366 11483 8623 8177 -224 -1829 -272 C +ATOM 2850 CG ARG A 366 -5.563 7.648 18.020 1.00 78.50 C +ANISOU 2850 CG ARG A 366 11840 9132 8853 -259 -1736 -313 C +ATOM 2851 CD ARG A 366 -7.039 7.310 17.813 1.00 83.50 C +ANISOU 2851 CD ARG A 366 12338 9726 9662 -350 -1935 -321 C +ATOM 2852 NE ARG A 366 -7.703 7.004 19.090 1.00 87.46 N +ANISOU 2852 NE ARG A 366 12604 10244 10381 -373 -1823 -341 N +ATOM 2853 CZ ARG A 366 -8.343 7.890 19.863 1.00 90.18 C +ANISOU 2853 CZ ARG A 366 12703 10624 10936 -336 -1794 -323 C +ATOM 2854 NH1 ARG A 366 -8.439 9.172 19.513 1.00 91.09 N +ANISOU 2854 NH1 ARG A 366 12760 10752 11096 -260 -1888 -279 N +ATOM 2855 NH2 ARG A 366 -8.885 7.498 21.015 1.00 91.28 N +ANISOU 2855 NH2 ARG A 366 12660 10779 11242 -378 -1661 -353 N +ATOM 2856 N LYS A 367 -3.322 10.826 18.433 1.00 57.45 N +ANISOU 2856 N LYS A 367 9198 6589 6041 -16 -1491 -193 N +ATOM 2857 CA LYS A 367 -3.389 11.538 19.685 1.00 53.87 C +ANISOU 2857 CA LYS A 367 8544 6172 5749 46 -1370 -177 C +ATOM 2858 C LYS A 367 -4.680 11.114 20.393 1.00 51.68 C +ANISOU 2858 C LYS A 367 8057 5881 5696 1 -1410 -204 C +ATOM 2859 O LYS A 367 -5.772 11.457 19.971 1.00 52.80 O +ANISOU 2859 O LYS A 367 8095 5993 5972 -21 -1590 -192 O +ATOM 2860 CB LYS A 367 -3.402 13.025 19.402 1.00 54.58 C +ANISOU 2860 CB LYS A 367 8603 6267 5866 102 -1444 -117 C +ATOM 2861 CG LYS A 367 -3.350 13.890 20.639 1.00 55.48 C +ANISOU 2861 CG LYS A 367 8538 6414 6125 171 -1310 -108 C +ATOM 2862 CD LYS A 367 -3.226 15.356 20.266 1.00 56.57 C +ANISOU 2862 CD LYS A 367 8682 6540 6271 228 -1386 -48 C +ATOM 2863 CE LYS A 367 -3.492 16.237 21.462 1.00 57.33 C +ANISOU 2863 CE LYS A 367 8578 6650 6554 291 -1286 -54 C +ATOM 2864 NZ LYS A 367 -2.988 17.614 21.209 1.00 58.85 N +ANISOU 2864 NZ LYS A 367 8819 6828 6712 350 -1313 2 N +ATOM 2865 N ALA A 368 -4.546 10.340 21.452 1.00 47.85 N +ANISOU 2865 N ALA A 368 7514 5411 5254 -16 -1246 -239 N +ATOM 2866 CA ALA A 368 -5.694 9.750 22.124 1.00 47.09 C +ANISOU 2866 CA ALA A 368 7244 5302 5346 -87 -1251 -272 C +ATOM 2867 C ALA A 368 -6.377 10.682 23.132 1.00 45.92 C +ANISOU 2867 C ALA A 368 6855 5184 5409 -56 -1181 -273 C +ATOM 2868 O ALA A 368 -7.496 10.410 23.574 1.00 47.04 O +ANISOU 2868 O ALA A 368 6817 5317 5738 -117 -1195 -306 O +ATOM 2869 CB ALA A 368 -5.253 8.503 22.841 1.00 46.50 C +ANISOU 2869 CB ALA A 368 7237 5219 5211 -136 -1106 -304 C +ATOM 2870 N GLY A 369 -5.708 11.771 23.514 1.00 43.27 N +ANISOU 2870 N GLY A 369 6512 4879 5048 31 -1093 -247 N +ATOM 2871 CA GLY A 369 -6.277 12.718 24.463 1.00 41.94 C +ANISOU 2871 CA GLY A 369 6134 4731 5070 68 -1012 -261 C +ATOM 2872 C GLY A 369 -5.224 13.626 25.037 1.00 39.61 C +ANISOU 2872 C GLY A 369 5890 4468 4690 149 -875 -238 C +ATOM 2873 O GLY A 369 -4.062 13.604 24.604 1.00 38.98 O +ANISOU 2873 O GLY A 369 5992 4399 4417 180 -858 -205 O +ATOM 2874 N TYR A 370 -5.640 14.444 25.992 1.00 38.51 N +ANISOU 2874 N TYR A 370 5586 4343 4703 179 -775 -263 N +ATOM 2875 CA TYR A 370 -4.732 15.301 26.732 1.00 36.78 C +ANISOU 2875 CA TYR A 370 5401 4151 4421 241 -633 -251 C +ATOM 2876 C TYR A 370 -4.937 15.188 28.256 1.00 35.90 C +ANISOU 2876 C TYR A 370 5186 4067 4383 203 -424 -302 C +ATOM 2877 O TYR A 370 -5.996 14.777 28.740 1.00 35.99 O +ANISOU 2877 O TYR A 370 5050 4077 4548 139 -383 -354 O +ATOM 2878 CB TYR A 370 -4.879 16.753 26.260 1.00 37.17 C +ANISOU 2878 CB TYR A 370 5397 4172 4552 328 -734 -225 C +ATOM 2879 CG TYR A 370 -6.210 17.392 26.546 1.00 38.69 C +ANISOU 2879 CG TYR A 370 5353 4332 5014 349 -777 -272 C +ATOM 2880 CD1 TYR A 370 -7.255 17.331 25.630 1.00 40.34 C +ANISOU 2880 CD1 TYR A 370 5469 4495 5363 343 -989 -268 C +ATOM 2881 CD2 TYR A 370 -6.421 18.087 27.731 1.00 39.00 C +ANISOU 2881 CD2 TYR A 370 5258 4382 5177 375 -609 -327 C +ATOM 2882 CE1 TYR A 370 -8.483 17.925 25.897 1.00 42.10 C +ANISOU 2882 CE1 TYR A 370 5442 4682 5870 372 -1033 -319 C +ATOM 2883 CE2 TYR A 370 -7.636 18.690 28.008 1.00 40.55 C +ANISOU 2883 CE2 TYR A 370 5217 4543 5644 403 -627 -388 C +ATOM 2884 CZ TYR A 370 -8.659 18.598 27.094 1.00 42.43 C +ANISOU 2884 CZ TYR A 370 5340 4736 6045 406 -839 -385 C +ATOM 2885 OH TYR A 370 -9.854 19.203 27.394 1.00 45.04 O +ANISOU 2885 OH TYR A 370 5407 5027 6677 444 -857 -454 O +ATOM 2886 N TRP A 371 -3.888 15.539 28.989 1.00 34.42 N +ANISOU 2886 N TRP A 371 5089 3907 4079 230 -291 -288 N +ATOM 2887 CA TRP A 371 -3.906 15.583 30.444 1.00 34.59 C +ANISOU 2887 CA TRP A 371 5062 3954 4127 190 -96 -329 C +ATOM 2888 C TRP A 371 -3.496 16.968 30.926 1.00 34.35 C +ANISOU 2888 C TRP A 371 5008 3928 4116 262 -31 -335 C +ATOM 2889 O TRP A 371 -2.534 17.531 30.433 1.00 32.74 O +ANISOU 2889 O TRP A 371 4911 3724 3805 324 -84 -285 O +ATOM 2890 CB TRP A 371 -2.940 14.525 31.006 1.00 33.53 C +ANISOU 2890 CB TRP A 371 5091 3836 3813 135 -10 -304 C +ATOM 2891 CG TRP A 371 -2.952 14.414 32.536 1.00 33.31 C +ANISOU 2891 CG TRP A 371 5054 3825 3775 66 177 -336 C +ATOM 2892 CD1 TRP A 371 -3.649 13.508 33.283 1.00 34.07 C +ANISOU 2892 CD1 TRP A 371 5121 3918 3905 -46 269 -368 C +ATOM 2893 CD2 TRP A 371 -2.242 15.226 33.466 1.00 32.38 C +ANISOU 2893 CD2 TRP A 371 4979 3726 3597 89 289 -337 C +ATOM 2894 NE1 TRP A 371 -3.423 13.704 34.602 1.00 33.80 N +ANISOU 2894 NE1 TRP A 371 5121 3900 3821 -99 433 -387 N +ATOM 2895 CE2 TRP A 371 -2.558 14.752 34.755 1.00 33.19 C +ANISOU 2895 CE2 TRP A 371 5088 3836 3685 -15 444 -370 C +ATOM 2896 CE3 TRP A 371 -1.363 16.300 33.342 1.00 31.60 C +ANISOU 2896 CE3 TRP A 371 4924 3635 3446 175 272 -312 C +ATOM 2897 CZ2 TRP A 371 -2.027 15.333 35.935 1.00 32.81 C +ANISOU 2897 CZ2 TRP A 371 5100 3802 3563 -35 576 -383 C +ATOM 2898 CZ3 TRP A 371 -0.846 16.881 34.502 1.00 31.50 C +ANISOU 2898 CZ3 TRP A 371 4952 3636 3378 160 399 -326 C +ATOM 2899 CH2 TRP A 371 -1.178 16.389 35.782 1.00 31.98 C +ANISOU 2899 CH2 TRP A 371 5030 3704 3417 56 544 -362 C +ATOM 2900 N ASN A 372 -4.246 17.525 31.868 1.00 36.81 N +ANISOU 2900 N ASN A 372 5178 4238 4570 249 90 -402 N +ATOM 2901 CA ASN A 372 -3.784 18.680 32.662 1.00 37.15 C +ANISOU 2901 CA ASN A 372 5224 4282 4609 294 199 -424 C +ATOM 2902 C ASN A 372 -4.146 18.489 34.123 1.00 38.50 C +ANISOU 2902 C ASN A 372 5353 4473 4800 209 412 -496 C +ATOM 2903 O ASN A 372 -4.826 17.533 34.479 1.00 38.48 O +ANISOU 2903 O ASN A 372 5304 4484 4832 115 475 -528 O +ATOM 2904 CB ASN A 372 -4.317 20.007 32.103 1.00 38.18 C +ANISOU 2904 CB ASN A 372 5233 4364 4907 393 105 -440 C +ATOM 2905 CG ASN A 372 -5.825 20.128 32.170 1.00 40.39 C +ANISOU 2905 CG ASN A 372 5282 4616 5448 391 105 -521 C +ATOM 2906 OD1 ASN A 372 -6.425 20.051 33.233 1.00 41.76 O +ANISOU 2906 OD1 ASN A 372 5350 4803 5710 336 284 -607 O +ATOM 2907 ND2 ASN A 372 -6.442 20.382 31.030 1.00 41.58 N +ANISOU 2907 ND2 ASN A 372 5349 4721 5726 449 -97 -496 N +ATOM 2908 N GLU A 373 -3.702 19.418 34.962 1.00 40.55 N +ANISOU 2908 N GLU A 373 5642 4733 5031 230 525 -525 N +ATOM 2909 CA GLU A 373 -3.792 19.267 36.417 1.00 42.28 C +ANISOU 2909 CA GLU A 373 5886 4973 5204 134 737 -587 C +ATOM 2910 C GLU A 373 -5.211 19.286 36.945 1.00 44.43 C +ANISOU 2910 C GLU A 373 5965 5240 5675 81 869 -697 C +ATOM 2911 O GLU A 373 -5.491 18.639 37.940 1.00 44.93 O +ANISOU 2911 O GLU A 373 6056 5326 5686 -41 1035 -739 O +ATOM 2912 CB GLU A 373 -2.968 20.343 37.128 1.00 43.50 C +ANISOU 2912 CB GLU A 373 6128 5121 5276 168 813 -598 C +ATOM 2913 CG GLU A 373 -1.490 20.283 36.808 1.00 43.75 C +ANISOU 2913 CG GLU A 373 6341 5166 5114 199 714 -499 C +ATOM 2914 CD GLU A 373 -0.678 21.342 37.539 1.00 45.44 C +ANISOU 2914 CD GLU A 373 6638 5373 5253 217 778 -510 C +ATOM 2915 OE1 GLU A 373 -0.983 22.552 37.377 1.00 46.39 O +ANISOU 2915 OE1 GLU A 373 6677 5455 5493 291 776 -553 O +ATOM 2916 OE2 GLU A 373 0.272 20.962 38.276 1.00 47.53 O +ANISOU 2916 OE2 GLU A 373 7053 5659 5344 157 818 -474 O +ATOM 2917 N TYR A 374 -6.108 20.001 36.275 1.00 46.54 N +ANISOU 2917 N TYR A 374 6037 5472 6173 167 794 -743 N +ATOM 2918 CA TYR A 374 -7.481 20.156 36.749 1.00 49.69 C +ANISOU 2918 CA TYR A 374 6208 5860 6810 134 923 -865 C +ATOM 2919 C TYR A 374 -8.429 19.120 36.172 1.00 50.99 C +ANISOU 2919 C TYR A 374 6244 6035 7095 74 851 -866 C +ATOM 2920 O TYR A 374 -9.197 18.498 36.897 1.00 52.29 O +ANISOU 2920 O TYR A 374 6321 6223 7322 -44 1016 -939 O +ATOM 2921 CB TYR A 374 -7.950 21.577 36.452 1.00 51.51 C +ANISOU 2921 CB TYR A 374 6278 6030 7261 270 879 -926 C +ATOM 2922 CG TYR A 374 -6.922 22.611 36.900 1.00 51.83 C +ANISOU 2922 CG TYR A 374 6469 6052 7172 327 921 -914 C +ATOM 2923 CD1 TYR A 374 -6.791 22.976 38.264 1.00 53.45 C +ANISOU 2923 CD1 TYR A 374 6724 6268 7313 263 1163 -1003 C +ATOM 2924 CD2 TYR A 374 -6.058 23.201 35.984 1.00 50.51 C +ANISOU 2924 CD2 TYR A 374 6408 5854 6927 427 726 -813 C +ATOM 2925 CE1 TYR A 374 -5.844 23.916 38.671 1.00 52.92 C +ANISOU 2925 CE1 TYR A 374 6801 6180 7127 306 1188 -993 C +ATOM 2926 CE2 TYR A 374 -5.120 24.141 36.380 1.00 50.61 C +ANISOU 2926 CE2 TYR A 374 6551 5848 6830 467 761 -801 C +ATOM 2927 CZ TYR A 374 -5.015 24.505 37.714 1.00 51.72 C +ANISOU 2927 CZ TYR A 374 6731 5996 6924 410 982 -891 C +ATOM 2928 OH TYR A 374 -4.060 25.432 38.078 1.00 50.86 O +ANISOU 2928 OH TYR A 374 6758 5862 6702 442 998 -877 O +ATOM 2929 N GLU A 375 -8.364 18.919 34.861 1.00 52.03 N +ANISOU 2929 N GLU A 375 6377 6145 7246 140 606 -786 N +ATOM 2930 CA GLU A 375 -9.249 17.972 34.178 1.00 52.91 C +ANISOU 2930 CA GLU A 375 6375 6256 7472 85 499 -782 C +ATOM 2931 C GLU A 375 -8.732 16.553 34.270 1.00 51.66 C +ANISOU 2931 C GLU A 375 6395 6130 7100 -32 512 -720 C +ATOM 2932 O GLU A 375 -9.477 15.617 34.042 1.00 51.87 O +ANISOU 2932 O GLU A 375 6347 6160 7201 -119 484 -732 O +ATOM 2933 CB GLU A 375 -9.419 18.381 32.715 1.00 54.00 C +ANISOU 2933 CB GLU A 375 6463 6347 7705 197 215 -724 C +ATOM 2934 CG GLU A 375 -10.048 19.768 32.522 1.00 56.63 C +ANISOU 2934 CG GLU A 375 6606 6622 8287 322 158 -778 C +ATOM 2935 CD GLU A 375 -9.776 20.385 31.147 1.00 57.35 C +ANISOU 2935 CD GLU A 375 6752 6656 8381 437 -129 -686 C +ATOM 2936 OE1 GLU A 375 -10.434 19.962 30.165 1.00 58.80 O +ANISOU 2936 OE1 GLU A 375 6861 6815 8666 434 -333 -657 O +ATOM 2937 OE2 GLU A 375 -8.917 21.298 31.052 1.00 56.38 O +ANISOU 2937 OE2 GLU A 375 6756 6510 8155 518 -153 -642 O +ATOM 2938 N ARG A 376 -7.458 16.386 34.613 1.00 50.77 N +ANISOU 2938 N ARG A 376 6517 6036 6737 -35 547 -654 N +ATOM 2939 CA ARG A 376 -6.814 15.059 34.548 1.00 50.95 C +ANISOU 2939 CA ARG A 376 6726 6069 6561 -117 517 -584 C +ATOM 2940 C ARG A 376 -6.833 14.541 33.081 1.00 48.04 C +ANISOU 2940 C ARG A 376 6377 5677 6198 -74 282 -526 C +ATOM 2941 O ARG A 376 -6.668 15.335 32.168 1.00 46.55 O +ANISOU 2941 O ARG A 376 6168 5471 6046 35 136 -499 O +ATOM 2942 CB ARG A 376 -7.452 14.078 35.544 1.00 55.14 C +ANISOU 2942 CB ARG A 376 7241 6614 7096 -281 688 -629 C +ATOM 2943 CG ARG A 376 -7.710 14.670 36.932 1.00 59.40 C +ANISOU 2943 CG ARG A 376 7739 7174 7654 -342 934 -710 C +ATOM 2944 CD ARG A 376 -8.283 13.643 37.899 1.00 64.06 C +ANISOU 2944 CD ARG A 376 8350 7777 8213 -530 1110 -744 C +ATOM 2945 NE ARG A 376 -7.291 12.655 38.356 1.00 65.79 N +ANISOU 2945 NE ARG A 376 8835 7985 8174 -610 1109 -655 N +ATOM 2946 CZ ARG A 376 -7.076 11.449 37.812 1.00 67.34 C +ANISOU 2946 CZ ARG A 376 9135 8154 8294 -653 985 -584 C +ATOM 2947 NH1 ARG A 376 -7.749 11.035 36.730 1.00 68.89 N +ANISOU 2947 NH1 ARG A 376 9209 8336 8628 -634 843 -587 N +ATOM 2948 NH2 ARG A 376 -6.154 10.653 38.342 1.00 66.94 N +ANISOU 2948 NH2 ARG A 376 9322 8081 8031 -713 987 -510 N +ATOM 2949 N PHE A 377 -7.020 13.248 32.846 1.00 46.37 N +ANISOU 2949 N PHE A 377 6221 5457 5938 -166 241 -506 N +ATOM 2950 CA PHE A 377 -7.040 12.726 31.477 1.00 45.47 C +ANISOU 2950 CA PHE A 377 6148 5316 5811 -137 26 -462 C +ATOM 2951 C PHE A 377 -8.405 12.854 30.788 1.00 47.39 C +ANISOU 2951 C PHE A 377 6175 5539 6289 -147 -94 -505 C +ATOM 2952 O PHE A 377 -9.377 12.235 31.188 1.00 47.97 O +ANISOU 2952 O PHE A 377 6121 5614 6490 -254 -31 -556 O +ATOM 2953 CB PHE A 377 -6.566 11.280 31.437 1.00 44.11 C +ANISOU 2953 CB PHE A 377 6148 5126 5483 -222 14 -425 C +ATOM 2954 CG PHE A 377 -6.537 10.700 30.069 1.00 43.54 C +ANISOU 2954 CG PHE A 377 6144 5022 5376 -202 -187 -394 C +ATOM 2955 CD1 PHE A 377 -5.753 11.264 29.083 1.00 42.82 C +ANISOU 2955 CD1 PHE A 377 6150 4928 5191 -93 -312 -352 C +ATOM 2956 CD2 PHE A 377 -7.288 9.582 29.758 1.00 44.85 C +ANISOU 2956 CD2 PHE A 377 6291 5157 5592 -306 -249 -410 C +ATOM 2957 CE1 PHE A 377 -5.722 10.734 27.802 1.00 42.79 C +ANISOU 2957 CE1 PHE A 377 6234 4893 5131 -88 -488 -332 C +ATOM 2958 CE2 PHE A 377 -7.261 9.032 28.484 1.00 44.77 C +ANISOU 2958 CE2 PHE A 377 6364 5110 5533 -297 -438 -389 C +ATOM 2959 CZ PHE A 377 -6.483 9.616 27.501 1.00 43.83 C +ANISOU 2959 CZ PHE A 377 6352 4990 5309 -188 -556 -353 C +ATOM 2960 N VAL A 378 -8.449 13.666 29.739 1.00 48.58 N +ANISOU 2960 N VAL A 378 6292 5669 6497 -42 -276 -481 N +ATOM 2961 CA VAL A 378 -9.615 13.799 28.896 1.00 51.72 C +ANISOU 2961 CA VAL A 378 6511 6034 7106 -37 -454 -503 C +ATOM 2962 C VAL A 378 -9.384 13.037 27.573 1.00 52.39 C +ANISOU 2962 C VAL A 378 6748 6090 7068 -53 -676 -444 C +ATOM 2963 O VAL A 378 -8.572 13.459 26.761 1.00 51.28 O +ANISOU 2963 O VAL A 378 6762 5937 6783 23 -788 -385 O +ATOM 2964 CB VAL A 378 -9.863 15.286 28.581 1.00 52.47 C +ANISOU 2964 CB VAL A 378 6482 6103 7349 89 -540 -508 C +ATOM 2965 CG1 VAL A 378 -11.154 15.464 27.791 1.00 54.69 C +ANISOU 2965 CG1 VAL A 378 6551 6339 7888 99 -744 -532 C +ATOM 2966 CG2 VAL A 378 -9.882 16.102 29.861 1.00 52.45 C +ANISOU 2966 CG2 VAL A 378 6375 6122 7429 115 -309 -572 C +ATOM 2967 N PRO A 379 -10.099 11.922 27.347 1.00 54.90 N +ANISOU 2967 N PRO A 379 7028 6393 7437 -163 -731 -464 N +ATOM 2968 CA PRO A 379 -9.968 11.185 26.072 1.00 56.83 C +ANISOU 2968 CA PRO A 379 7422 6601 7568 -187 -946 -423 C +ATOM 2969 C PRO A 379 -10.784 11.835 24.923 1.00 60.12 C +ANISOU 2969 C PRO A 379 7731 6978 8133 -143 -1212 -410 C +ATOM 2970 O PRO A 379 -11.768 12.489 25.208 1.00 61.62 O +ANISOU 2970 O PRO A 379 7671 7161 8578 -124 -1230 -450 O +ATOM 2971 CB PRO A 379 -10.513 9.800 26.423 1.00 57.10 C +ANISOU 2971 CB PRO A 379 7442 6626 7626 -333 -894 -457 C +ATOM 2972 CG PRO A 379 -11.443 10.013 27.590 1.00 57.41 C +ANISOU 2972 CG PRO A 379 7233 6693 7885 -391 -719 -523 C +ATOM 2973 CD PRO A 379 -11.073 11.298 28.264 1.00 56.04 C +ANISOU 2973 CD PRO A 379 6997 6551 7743 -283 -590 -532 C +ATOM 2974 N PHE A 380 -10.370 11.707 23.667 1.00 64.02 N +ANISOU 2974 N PHE A 380 8412 7439 8473 -126 -1414 -358 N +ATOM 2975 CA PHE A 380 -11.233 12.139 22.527 1.00 68.71 C +ANISOU 2975 CA PHE A 380 8931 7981 9192 -114 -1707 -337 C +ATOM 2976 C PHE A 380 -12.163 10.986 22.117 1.00 71.86 C +ANISOU 2976 C PHE A 380 9276 8352 9674 -241 -1836 -368 C +ATOM 2977 O PHE A 380 -11.779 9.817 22.188 1.00 70.88 O +ANISOU 2977 O PHE A 380 9299 8232 9399 -327 -1760 -381 O +ATOM 2978 CB PHE A 380 -10.394 12.616 21.325 1.00 69.03 C +ANISOU 2978 CB PHE A 380 9223 7995 9009 -56 -1872 -263 C +ATOM 2979 CG PHE A 380 -9.424 13.722 21.654 1.00 68.79 C +ANISOU 2979 CG PHE A 380 9261 7987 8887 52 -1754 -228 C +ATOM 2980 CD1 PHE A 380 -9.814 14.815 22.439 1.00 70.15 C +ANISOU 2980 CD1 PHE A 380 9224 8162 9266 131 -1680 -246 C +ATOM 2981 CD2 PHE A 380 -8.112 13.682 21.181 1.00 67.60 C +ANISOU 2981 CD2 PHE A 380 9379 7852 8453 72 -1708 -185 C +ATOM 2982 CE1 PHE A 380 -8.910 15.829 22.756 1.00 68.67 C +ANISOU 2982 CE1 PHE A 380 9110 7989 8992 222 -1575 -215 C +ATOM 2983 CE2 PHE A 380 -7.210 14.689 21.492 1.00 66.63 C +ANISOU 2983 CE2 PHE A 380 9312 7751 8254 159 -1599 -153 C +ATOM 2984 CZ PHE A 380 -7.610 15.772 22.267 1.00 66.87 C +ANISOU 2984 CZ PHE A 380 9148 7779 8480 231 -1543 -163 C +ATOM 2985 N SER A 381 -13.385 11.314 21.690 1.00 76.79 N +ANISOU 2985 N SER A 381 9684 8939 10550 -253 -2041 -382 N +ATOM 2986 CA SER A 381 -14.411 10.310 21.274 1.00 80.71 C +ANISOU 2986 CA SER A 381 10090 9405 11169 -382 -2195 -414 C +ATOM 2987 C SER A 381 -14.941 9.423 22.418 1.00 81.21 C +ANISOU 2987 C SER A 381 9987 9503 11363 -495 -1968 -487 C +ATOM 2988 O SER A 381 -14.626 9.626 23.597 1.00 81.27 O +ANISOU 2988 O SER A 381 9933 9559 11385 -474 -1692 -517 O +ATOM 2989 CB SER A 381 -13.914 9.418 20.109 1.00 80.96 C +ANISOU 2989 CB SER A 381 10428 9399 10934 -451 -2367 -377 C +ATOM 2990 OG SER A 381 -13.853 10.132 18.883 1.00 82.31 O +ANISOU 2990 OG SER A 381 10717 9523 11031 -396 -2641 -315 O +TER 2991 SER A 381 +ATOM 2992 N PHE B 2 61.544 21.660 59.287 1.00123.84 N +ANISOU 2992 N PHE B 2 13231 17896 15925 -1053 -1377 -488 N +ATOM 2993 CA PHE B 2 60.174 21.156 59.635 1.00121.15 C +ANISOU 2993 CA PHE B 2 13218 17486 15324 -898 -1382 -483 C +ATOM 2994 C PHE B 2 59.477 22.112 60.621 1.00119.98 C +ANISOU 2994 C PHE B 2 13332 17271 14982 -1061 -1501 -608 C +ATOM 2995 O PHE B 2 60.088 22.551 61.598 1.00121.93 O +ANISOU 2995 O PHE B 2 13498 17607 15220 -1232 -1723 -679 O +ATOM 2996 CB PHE B 2 60.254 19.743 60.232 1.00121.89 C +ANISOU 2996 CB PHE B 2 13230 17706 15374 -688 -1545 -387 C +ATOM 2997 CG PHE B 2 58.929 19.020 60.274 1.00118.80 C +ANISOU 2997 CG PHE B 2 13130 17238 14770 -501 -1485 -357 C +ATOM 2998 CD1 PHE B 2 58.489 18.297 59.178 1.00117.15 C +ANISOU 2998 CD1 PHE B 2 12959 16960 14590 -325 -1254 -290 C +ATOM 2999 CD2 PHE B 2 58.122 19.073 61.404 1.00117.82 C +ANISOU 2999 CD2 PHE B 2 13243 17111 14409 -516 -1649 -404 C +ATOM 3000 CE1 PHE B 2 57.276 17.629 59.211 1.00115.16 C +ANISOU 3000 CE1 PHE B 2 12959 16641 14153 -171 -1206 -266 C +ATOM 3001 CE2 PHE B 2 56.911 18.409 61.447 1.00115.26 C +ANISOU 3001 CE2 PHE B 2 13167 16716 13908 -352 -1584 -374 C +ATOM 3002 CZ PHE B 2 56.488 17.682 60.347 1.00114.70 C +ANISOU 3002 CZ PHE B 2 13115 16580 13885 -180 -1370 -302 C +ATOM 3003 N PRO B 3 58.194 22.440 60.373 1.00115.39 N +ANISOU 3003 N PRO B 3 13061 16530 14249 -1016 -1352 -636 N +ATOM 3004 CA PRO B 3 57.518 23.469 61.194 1.00112.25 C +ANISOU 3004 CA PRO B 3 12914 16029 13705 -1174 -1401 -767 C +ATOM 3005 C PRO B 3 57.377 23.171 62.709 1.00109.37 C +ANISOU 3005 C PRO B 3 12647 15766 13142 -1205 -1667 -831 C +ATOM 3006 O PRO B 3 57.381 22.009 63.127 1.00108.15 O +ANISOU 3006 O PRO B 3 12445 15736 12910 -1043 -1798 -744 O +ATOM 3007 CB PRO B 3 56.133 23.601 60.528 1.00110.12 C +ANISOU 3007 CB PRO B 3 12916 15582 13342 -1056 -1179 -739 C +ATOM 3008 CG PRO B 3 55.977 22.396 59.649 1.00109.80 C +ANISOU 3008 CG PRO B 3 12803 15592 13324 -827 -1082 -603 C +ATOM 3009 CD PRO B 3 57.357 21.990 59.242 1.00112.74 C +ANISOU 3009 CD PRO B 3 12845 16095 13893 -840 -1113 -553 C +ATOM 3010 N ASN B 4 57.243 24.234 63.502 1.00106.03 N +ANISOU 3010 N ASN B 4 12374 15279 12633 -1421 -1728 -982 N +ATOM 3011 CA ASN B 4 56.979 24.128 64.948 1.00104.14 C +ANISOU 3011 CA ASN B 4 12293 15116 12159 -1490 -1949 -1069 C +ATOM 3012 C ASN B 4 55.571 23.608 65.188 1.00 98.58 C +ANISOU 3012 C ASN B 4 11877 14324 11253 -1307 -1861 -1047 C +ATOM 3013 O ASN B 4 55.318 22.851 66.134 1.00 97.77 O +ANISOU 3013 O ASN B 4 11860 14329 10959 -1239 -2026 -1029 O +ATOM 3014 CB ASN B 4 57.065 25.494 65.645 1.00106.16 C +ANISOU 3014 CB ASN B 4 12685 15284 12366 -1784 -1978 -1268 C +ATOM 3015 CG ASN B 4 58.413 26.155 65.495 1.00109.67 C +ANISOU 3015 CG ASN B 4 12860 15802 13008 -2011 -2067 -1315 C +ATOM 3016 OD1 ASN B 4 59.434 25.486 65.307 1.00110.86 O +ANISOU 3016 OD1 ASN B 4 12701 16133 13287 -1971 -2205 -1207 O +ATOM 3017 ND2 ASN B 4 58.428 27.488 65.575 1.00110.59 N +ANISOU 3017 ND2 ASN B 4 13085 15765 13169 -2254 -1976 -1475 N +ATOM 3018 N THR B 5 54.649 24.065 64.340 1.00 92.69 N +ANISOU 3018 N THR B 5 11279 13381 10555 -1239 -1601 -1042 N +ATOM 3019 CA THR B 5 53.243 23.746 64.468 1.00 87.86 C +ANISOU 3019 CA THR B 5 10929 12662 9791 -1085 -1488 -1026 C +ATOM 3020 C THR B 5 52.702 23.060 63.210 1.00 82.73 C +ANISOU 3020 C THR B 5 10241 11964 9225 -865 -1310 -875 C +ATOM 3021 O THR B 5 52.956 23.494 62.081 1.00 81.80 O +ANISOU 3021 O THR B 5 10023 11778 9276 -880 -1159 -829 O +ATOM 3022 CB THR B 5 52.419 25.018 64.729 1.00 87.73 C +ANISOU 3022 CB THR B 5 11160 12433 9741 -1216 -1339 -1165 C +ATOM 3023 OG1 THR B 5 53.051 25.795 65.753 1.00 91.04 O +ANISOU 3023 OG1 THR B 5 11609 12881 10100 -1465 -1478 -1333 O +ATOM 3024 CG2 THR B 5 51.007 24.659 65.148 1.00 85.97 C +ANISOU 3024 CG2 THR B 5 11192 12121 9349 -1072 -1254 -1162 C +ATOM 3025 N ILE B 6 51.941 21.990 63.427 1.00 77.54 N +ANISOU 3025 N ILE B 6 9678 11345 8437 -675 -1328 -800 N +ATOM 3026 CA ILE B 6 51.138 21.376 62.388 1.00 72.42 C +ANISOU 3026 CA ILE B 6 9064 10632 7818 -487 -1158 -685 C +ATOM 3027 C ILE B 6 49.668 21.635 62.684 1.00 68.73 C +ANISOU 3027 C ILE B 6 8863 10022 7228 -435 -1049 -714 C +ATOM 3028 O ILE B 6 49.190 21.304 63.765 1.00 68.80 O +ANISOU 3028 O ILE B 6 9012 10056 7071 -416 -1138 -760 O +ATOM 3029 CB ILE B 6 51.360 19.856 62.346 1.00 72.33 C +ANISOU 3029 CB ILE B 6 8947 10759 7777 -303 -1243 -573 C +ATOM 3030 CG1 ILE B 6 52.815 19.534 61.990 1.00 73.84 C +ANISOU 3030 CG1 ILE B 6 8843 11082 8130 -327 -1326 -528 C +ATOM 3031 CG2 ILE B 6 50.401 19.206 61.352 1.00 70.43 C +ANISOU 3031 CG2 ILE B 6 8780 10446 7533 -131 -1069 -478 C +ATOM 3032 CD1 ILE B 6 53.235 20.048 60.628 1.00 74.00 C +ANISOU 3032 CD1 ILE B 6 8737 11044 8335 -367 -1143 -501 C +ATOM 3033 N SER B 7 48.954 22.214 61.719 1.00 65.60 N +ANISOU 3033 N SER B 7 8530 9479 6916 -411 -856 -674 N +ATOM 3034 CA SER B 7 47.523 22.529 61.861 1.00 62.79 C +ANISOU 3034 CA SER B 7 8389 8972 6493 -352 -733 -679 C +ATOM 3035 C SER B 7 46.643 21.550 61.133 1.00 58.71 C +ANISOU 3035 C SER B 7 7896 8465 5946 -163 -660 -549 C +ATOM 3036 O SER B 7 46.940 21.179 60.011 1.00 57.86 O +ANISOU 3036 O SER B 7 7670 8395 5915 -112 -608 -454 O +ATOM 3037 CB SER B 7 47.248 23.926 61.333 1.00 63.46 C +ANISOU 3037 CB SER B 7 8529 8872 6711 -456 -577 -705 C +ATOM 3038 OG SER B 7 47.830 24.868 62.218 1.00 66.80 O +ANISOU 3038 OG SER B 7 8986 9253 7140 -645 -630 -859 O +ATOM 3039 N ILE B 8 45.561 21.122 61.771 1.00 55.75 N +ANISOU 3039 N ILE B 8 7677 8054 5451 -74 -649 -553 N +ATOM 3040 CA ILE B 8 44.610 20.276 61.083 1.00 52.58 C +ANISOU 3040 CA ILE B 8 7304 7646 5026 82 -574 -438 C +ATOM 3041 C ILE B 8 43.232 20.899 61.098 1.00 51.56 C +ANISOU 3041 C ILE B 8 7325 7357 4907 110 -441 -428 C +ATOM 3042 O ILE B 8 42.933 21.781 61.899 1.00 52.10 O +ANISOU 3042 O ILE B 8 7504 7318 4972 33 -403 -526 O +ATOM 3043 CB ILE B 8 44.608 18.819 61.594 1.00 51.44 C +ANISOU 3043 CB ILE B 8 7156 7628 4760 200 -678 -405 C +ATOM 3044 CG1 ILE B 8 44.039 18.688 62.995 1.00 51.49 C +ANISOU 3044 CG1 ILE B 8 7322 7624 4618 200 -733 -478 C +ATOM 3045 CG2 ILE B 8 46.022 18.255 61.544 1.00 52.59 C +ANISOU 3045 CG2 ILE B 8 7122 7918 4941 185 -803 -397 C +ATOM 3046 CD1 ILE B 8 44.237 17.299 63.577 1.00 51.07 C +ANISOU 3046 CD1 ILE B 8 7257 7697 4449 300 -854 -431 C +ATOM 3047 N GLY B 9 42.418 20.463 60.146 1.00 49.63 N +ANISOU 3047 N GLY B 9 7075 7093 4689 213 -362 -307 N +ATOM 3048 CA GLY B 9 41.053 20.898 60.041 1.00 49.10 C +ANISOU 3048 CA GLY B 9 7108 6890 4655 264 -247 -260 C +ATOM 3049 C GLY B 9 40.132 19.920 60.723 1.00 48.51 C +ANISOU 3049 C GLY B 9 7121 6842 4465 370 -260 -256 C +ATOM 3050 O GLY B 9 40.465 18.753 60.913 1.00 48.78 O +ANISOU 3050 O GLY B 9 7129 7001 4402 425 -348 -247 O +ATOM 3051 N GLY B 10 38.974 20.411 61.125 1.00 49.02 N +ANISOU 3051 N GLY B 10 7288 6777 4559 398 -158 -259 N +ATOM 3052 CA GLY B 10 37.925 19.589 61.710 1.00 48.76 C +ANISOU 3052 CA GLY B 10 7336 6747 4441 494 -134 -244 C +ATOM 3053 C GLY B 10 36.622 19.929 61.027 1.00 48.76 C +ANISOU 3053 C GLY B 10 7330 6637 4559 560 -16 -133 C +ATOM 3054 O GLY B 10 36.207 21.081 61.083 1.00 49.86 O +ANISOU 3054 O GLY B 10 7496 6624 4821 531 88 -142 O +ATOM 3055 N LEU B 11 36.007 18.951 60.351 1.00 47.76 N +ANISOU 3055 N LEU B 11 7158 6580 4408 641 -35 -22 N +ATOM 3056 CA LEU B 11 34.655 19.105 59.839 1.00 47.60 C +ANISOU 3056 CA LEU B 11 7119 6479 4485 704 48 93 C +ATOM 3057 C LEU B 11 33.682 18.218 60.589 1.00 47.01 C +ANISOU 3057 C LEU B 11 7105 6411 4343 776 78 84 C +ATOM 3058 O LEU B 11 33.721 16.995 60.436 1.00 46.15 O +ANISOU 3058 O LEU B 11 6987 6415 4133 810 9 108 O +ATOM 3059 CB LEU B 11 34.596 18.749 58.368 1.00 47.49 C +ANISOU 3059 CB LEU B 11 7005 6544 4495 711 2 236 C +ATOM 3060 CG LEU B 11 35.314 19.705 57.453 1.00 48.77 C +ANISOU 3060 CG LEU B 11 7106 6683 4739 640 3 285 C +ATOM 3061 CD1 LEU B 11 34.960 19.359 56.014 1.00 48.57 C +ANISOU 3061 CD1 LEU B 11 7009 6732 4712 643 -27 443 C +ATOM 3062 CD2 LEU B 11 34.954 21.147 57.793 1.00 50.96 C +ANISOU 3062 CD2 LEU B 11 7409 6778 5173 621 105 283 C +ATOM 3063 N PHE B 12 32.797 18.841 61.369 1.00 47.53 N +ANISOU 3063 N PHE B 12 7235 6343 4481 799 200 50 N +ATOM 3064 CA PHE B 12 31.831 18.116 62.183 1.00 47.93 C +ANISOU 3064 CA PHE B 12 7349 6382 4478 858 262 34 C +ATOM 3065 C PHE B 12 30.411 18.356 61.688 1.00 49.88 C +ANISOU 3065 C PHE B 12 7520 6539 4892 925 361 161 C +ATOM 3066 O PHE B 12 30.092 19.449 61.225 1.00 50.65 O +ANISOU 3066 O PHE B 12 7560 6521 5162 928 429 222 O +ATOM 3067 CB PHE B 12 31.998 18.503 63.660 1.00 48.03 C +ANISOU 3067 CB PHE B 12 7512 6328 4408 821 336 -126 C +ATOM 3068 CG PHE B 12 33.292 18.019 64.242 1.00 47.02 C +ANISOU 3068 CG PHE B 12 7447 6324 4095 759 202 -226 C +ATOM 3069 CD1 PHE B 12 34.449 18.750 64.082 1.00 47.19 C +ANISOU 3069 CD1 PHE B 12 7446 6359 4125 673 133 -288 C +ATOM 3070 CD2 PHE B 12 33.371 16.793 64.864 1.00 46.35 C +ANISOU 3070 CD2 PHE B 12 7420 6345 3844 788 135 -235 C +ATOM 3071 CE1 PHE B 12 35.653 18.292 64.566 1.00 47.09 C +ANISOU 3071 CE1 PHE B 12 7454 6472 3965 618 -8 -358 C +ATOM 3072 CE2 PHE B 12 34.578 16.330 65.365 1.00 46.43 C +ANISOU 3072 CE2 PHE B 12 7463 6474 3704 743 -7 -295 C +ATOM 3073 CZ PHE B 12 35.721 17.085 65.218 1.00 46.61 C +ANISOU 3073 CZ PHE B 12 7446 6519 3744 658 -85 -356 C +ATOM 3074 N MET B 13 29.582 17.320 61.798 1.00 51.75 N +ANISOU 3074 N MET B 13 7747 6825 5089 975 366 209 N +ATOM 3075 CA MET B 13 28.202 17.341 61.344 1.00 53.83 C +ANISOU 3075 CA MET B 13 7911 7033 5508 1033 437 340 C +ATOM 3076 C MET B 13 27.249 17.449 62.522 1.00 55.04 C +ANISOU 3076 C MET B 13 8130 7072 5711 1076 609 280 C +ATOM 3077 O MET B 13 27.669 17.552 63.670 1.00 55.95 O +ANISOU 3077 O MET B 13 8389 7152 5714 1051 672 132 O +ATOM 3078 CB MET B 13 27.878 16.032 60.667 1.00 54.56 C +ANISOU 3078 CB MET B 13 7944 7259 5525 1039 336 424 C +ATOM 3079 CG MET B 13 28.518 15.798 59.330 1.00 56.31 C +ANISOU 3079 CG MET B 13 8093 7594 5707 995 196 502 C +ATOM 3080 SD MET B 13 27.941 14.190 58.687 1.00 58.82 S +ANISOU 3080 SD MET B 13 8371 8042 5935 986 115 568 S +ATOM 3081 CE MET B 13 26.165 14.426 58.495 1.00 59.49 C +ANISOU 3081 CE MET B 13 8333 8060 6209 1022 182 711 C +ATOM 3082 N ARG B 14 25.957 17.412 62.214 1.00 55.91 N +ANISOU 3082 N ARG B 14 8128 7131 5983 1133 682 399 N +ATOM 3083 CA ARG B 14 24.915 17.206 63.205 1.00 57.88 C +ANISOU 3083 CA ARG B 14 8413 7296 6282 1178 853 364 C +ATOM 3084 C ARG B 14 25.152 15.881 63.965 1.00 57.60 C +ANISOU 3084 C ARG B 14 8501 7367 6017 1155 818 280 C +ATOM 3085 O ARG B 14 25.533 14.865 63.370 1.00 58.36 O +ANISOU 3085 O ARG B 14 8573 7598 6001 1134 667 324 O +ATOM 3086 CB ARG B 14 23.539 17.185 62.518 1.00 57.41 C +ANISOU 3086 CB ARG B 14 8163 7204 6446 1237 891 540 C +ATOM 3087 N ASN B 15 24.932 15.905 65.270 1.00 57.91 N +ANISOU 3087 N ASN B 15 8680 7335 5987 1156 970 162 N +ATOM 3088 CA ASN B 15 25.033 14.701 66.110 1.00 58.79 C +ANISOU 3088 CA ASN B 15 8920 7527 5888 1139 960 105 C +ATOM 3089 C ASN B 15 26.428 14.077 66.124 1.00 54.35 C +ANISOU 3089 C ASN B 15 8447 7099 5102 1093 770 53 C +ATOM 3090 O ASN B 15 26.574 12.879 65.921 1.00 51.96 O +ANISOU 3090 O ASN B 15 8144 6896 4701 1097 673 100 O +ATOM 3091 CB ASN B 15 23.950 13.664 65.739 1.00 60.62 C +ANISOU 3091 CB ASN B 15 9047 7795 6189 1171 976 222 C +ATOM 3092 CG ASN B 15 22.568 14.038 66.302 1.00 65.80 C +ANISOU 3092 CG ASN B 15 9658 8319 7023 1215 1209 241 C +ATOM 3093 OD1 ASN B 15 22.069 15.175 66.121 1.00 67.79 O +ANISOU 3093 OD1 ASN B 15 9818 8449 7487 1252 1320 265 O +ATOM 3094 ND2 ASN B 15 21.948 13.085 67.019 1.00 68.45 N +ANISOU 3094 ND2 ASN B 15 10055 8665 7285 1213 1301 234 N +ATOM 3095 N THR B 16 27.434 14.916 66.369 1.00 51.96 N +ANISOU 3095 N THR B 16 8213 6786 4742 1048 729 -42 N +ATOM 3096 CA THR B 16 28.809 14.478 66.555 1.00 49.74 C +ANISOU 3096 CA THR B 16 8006 6625 4268 1002 560 -99 C +ATOM 3097 C THR B 16 29.415 15.231 67.746 1.00 48.95 C +ANISOU 3097 C THR B 16 8070 6487 4042 933 604 -252 C +ATOM 3098 O THR B 16 30.600 15.524 67.766 1.00 47.94 O +ANISOU 3098 O THR B 16 7963 6421 3831 875 475 -311 O +ATOM 3099 CB THR B 16 29.684 14.690 65.265 1.00 49.30 C +ANISOU 3099 CB THR B 16 7816 6635 4277 989 405 -42 C +ATOM 3100 OG1 THR B 16 29.720 16.080 64.905 1.00 50.87 O +ANISOU 3100 OG1 THR B 16 7968 6734 4623 965 463 -59 O +ATOM 3101 CG2 THR B 16 29.154 13.900 64.038 1.00 47.97 C +ANISOU 3101 CG2 THR B 16 7509 6523 4192 1029 349 95 C +ATOM 3102 N VAL B 17 28.596 15.531 68.745 1.00 49.72 N +ANISOU 3102 N VAL B 17 8284 6483 4121 928 792 -323 N +ATOM 3103 CA VAL B 17 29.067 16.274 69.932 1.00 51.06 C +ANISOU 3103 CA VAL B 17 8641 6610 4146 838 857 -492 C +ATOM 3104 C VAL B 17 30.130 15.511 70.741 1.00 50.78 C +ANISOU 3104 C VAL B 17 8740 6729 3824 775 685 -539 C +ATOM 3105 O VAL B 17 31.153 16.082 71.101 1.00 51.69 O +ANISOU 3105 O VAL B 17 8920 6883 3834 683 588 -639 O +ATOM 3106 CB VAL B 17 27.907 16.690 70.863 1.00 52.44 C +ANISOU 3106 CB VAL B 17 8932 6640 4351 842 1131 -568 C +ATOM 3107 CG1 VAL B 17 28.442 17.261 72.176 1.00 54.67 C +ANISOU 3107 CG1 VAL B 17 9451 6903 4416 723 1191 -760 C +ATOM 3108 CG2 VAL B 17 27.009 17.712 70.175 1.00 52.59 C +ANISOU 3108 CG2 VAL B 17 8812 6485 4684 902 1303 -531 C +ATOM 3109 N GLN B 18 29.899 14.230 71.020 1.00 49.51 N +ANISOU 3109 N GLN B 18 8612 6652 3545 820 642 -456 N +ATOM 3110 CA GLN B 18 30.874 13.429 71.777 1.00 49.41 C +ANISOU 3110 CA GLN B 18 8713 6782 3276 778 469 -461 C +ATOM 3111 C GLN B 18 32.189 13.332 71.021 1.00 48.54 C +ANISOU 3111 C GLN B 18 8475 6783 3184 773 234 -424 C +ATOM 3112 O GLN B 18 33.272 13.499 71.608 1.00 48.64 O +ANISOU 3112 O GLN B 18 8553 6886 3042 695 89 -485 O +ATOM 3113 CB GLN B 18 30.343 12.017 72.059 1.00 49.05 C +ANISOU 3113 CB GLN B 18 8707 6783 3145 844 476 -349 C +ATOM 3114 CG GLN B 18 31.083 11.286 73.172 1.00 50.04 C +ANISOU 3114 CG GLN B 18 8999 7025 2988 800 350 -346 C +ATOM 3115 CD GLN B 18 30.703 9.807 73.276 1.00 49.79 C +ANISOU 3115 CD GLN B 18 8984 7028 2903 876 336 -206 C +ATOM 3116 OE1 GLN B 18 31.174 8.982 72.487 1.00 49.72 O +ANISOU 3116 OE1 GLN B 18 8846 7072 2970 945 201 -101 O +ATOM 3117 NE2 GLN B 18 29.852 9.459 74.231 1.00 50.30 N +ANISOU 3117 NE2 GLN B 18 9212 7051 2845 860 495 -208 N +ATOM 3118 N GLU B 19 32.077 13.048 69.717 1.00 47.03 N +ANISOU 3118 N GLU B 19 8099 6589 3179 847 200 -323 N +ATOM 3119 CA GLU B 19 33.237 12.960 68.825 1.00 46.52 C +ANISOU 3119 CA GLU B 19 7895 6614 3166 848 19 -285 C +ATOM 3120 C GLU B 19 34.041 14.256 68.781 1.00 46.32 C +ANISOU 3120 C GLU B 19 7851 6572 3174 756 -17 -389 C +ATOM 3121 O GLU B 19 35.270 14.237 68.801 1.00 45.89 O +ANISOU 3121 O GLU B 19 7758 6618 3060 711 -182 -406 O +ATOM 3122 CB GLU B 19 32.796 12.575 67.414 1.00 46.59 C +ANISOU 3122 CB GLU B 19 7737 6607 3356 921 32 -178 C +ATOM 3123 CG GLU B 19 32.184 11.166 67.329 1.00 47.37 C +ANISOU 3123 CG GLU B 19 7839 6731 3427 995 44 -81 C +ATOM 3124 CD GLU B 19 30.652 11.146 67.458 1.00 48.39 C +ANISOU 3124 CD GLU B 19 7994 6761 3631 1021 224 -55 C +ATOM 3125 OE1 GLU B 19 30.055 11.941 68.259 1.00 49.88 O +ANISOU 3125 OE1 GLU B 19 8274 6866 3812 992 361 -127 O +ATOM 3126 OE2 GLU B 19 30.042 10.302 66.765 1.00 48.51 O +ANISOU 3126 OE2 GLU B 19 7934 6779 3719 1065 237 32 O +ATOM 3127 N HIS B 20 33.341 15.384 68.763 1.00 46.21 N +ANISOU 3127 N HIS B 20 7862 6423 3273 727 143 -454 N +ATOM 3128 CA HIS B 20 33.988 16.683 68.923 1.00 46.94 C +ANISOU 3128 CA HIS B 20 7977 6463 3392 622 145 -575 C +ATOM 3129 C HIS B 20 34.774 16.741 70.247 1.00 47.75 C +ANISOU 3129 C HIS B 20 8243 6642 3255 510 57 -699 C +ATOM 3130 O HIS B 20 35.929 17.159 70.266 1.00 48.38 O +ANISOU 3130 O HIS B 20 8291 6793 3298 420 -85 -755 O +ATOM 3131 CB HIS B 20 32.959 17.824 68.799 1.00 47.89 C +ANISOU 3131 CB HIS B 20 8113 6390 3690 625 369 -618 C +ATOM 3132 CG HIS B 20 33.543 19.195 68.964 1.00 49.71 C +ANISOU 3132 CG HIS B 20 8384 6531 3973 514 404 -749 C +ATOM 3133 ND1 HIS B 20 34.080 19.910 67.916 1.00 49.43 N +ANISOU 3133 ND1 HIS B 20 8209 6463 4107 497 360 -711 N +ATOM 3134 CD2 HIS B 20 33.670 19.984 70.060 1.00 52.38 C +ANISOU 3134 CD2 HIS B 20 8895 6795 4208 399 490 -926 C +ATOM 3135 CE1 HIS B 20 34.509 21.080 68.353 1.00 51.29 C +ANISOU 3135 CE1 HIS B 20 8523 6600 4365 381 417 -852 C +ATOM 3136 NE2 HIS B 20 34.286 21.144 69.653 1.00 53.27 N +ANISOU 3136 NE2 HIS B 20 8966 6826 4448 315 494 -994 N +ATOM 3137 N SER B 21 34.177 16.277 71.339 1.00 47.84 N +ANISOU 3137 N SER B 21 8426 6655 3094 505 131 -732 N +ATOM 3138 CA SER B 21 34.892 16.245 72.618 1.00 49.22 C +ANISOU 3138 CA SER B 21 8774 6927 2999 386 28 -832 C +ATOM 3139 C SER B 21 36.081 15.299 72.592 1.00 48.84 C +ANISOU 3139 C SER B 21 8646 7069 2839 396 -244 -737 C +ATOM 3140 O SER B 21 37.164 15.648 73.049 1.00 50.12 O +ANISOU 3140 O SER B 21 8825 7328 2888 282 -408 -804 O +ATOM 3141 CB SER B 21 33.951 15.879 73.752 1.00 50.14 C +ANISOU 3141 CB SER B 21 9101 7008 2939 380 180 -870 C +ATOM 3142 OG SER B 21 33.078 16.950 74.004 1.00 50.65 O +ANISOU 3142 OG SER B 21 9258 6894 3093 340 436 -998 O +ATOM 3143 N ALA B 22 35.883 14.109 72.048 1.00 47.44 N +ANISOU 3143 N ALA B 22 8372 6940 2710 528 -288 -581 N +ATOM 3144 CA ALA B 22 36.975 13.143 71.905 1.00 47.77 C +ANISOU 3144 CA ALA B 22 8312 7135 2701 567 -519 -472 C +ATOM 3145 C ALA B 22 38.111 13.706 71.066 1.00 47.92 C +ANISOU 3145 C ALA B 22 8147 7201 2858 530 -647 -488 C +ATOM 3146 O ALA B 22 39.286 13.441 71.333 1.00 48.74 O +ANISOU 3146 O ALA B 22 8189 7437 2892 494 -851 -464 O +ATOM 3147 CB ALA B 22 36.464 11.850 71.276 1.00 46.19 C +ANISOU 3147 CB ALA B 22 8035 6932 2581 717 -495 -319 C +ATOM 3148 N PHE B 23 37.753 14.478 70.045 1.00 47.46 N +ANISOU 3148 N PHE B 23 7991 7036 3004 540 -527 -513 N +ATOM 3149 CA PHE B 23 38.741 15.097 69.169 1.00 48.05 C +ANISOU 3149 CA PHE B 23 7897 7136 3221 497 -611 -526 C +ATOM 3150 C PHE B 23 39.567 16.122 69.933 1.00 50.23 C +ANISOU 3150 C PHE B 23 8233 7441 3412 332 -692 -666 C +ATOM 3151 O PHE B 23 40.796 16.067 69.918 1.00 50.47 O +ANISOU 3151 O PHE B 23 8155 7590 3431 278 -874 -659 O +ATOM 3152 CB PHE B 23 38.042 15.733 67.953 1.00 47.03 C +ANISOU 3152 CB PHE B 23 7678 6878 3310 537 -453 -505 C +ATOM 3153 CG PHE B 23 38.961 16.500 67.039 1.00 47.04 C +ANISOU 3153 CG PHE B 23 7530 6886 3456 479 -503 -517 C +ATOM 3154 CD1 PHE B 23 39.709 15.845 66.086 1.00 46.52 C +ANISOU 3154 CD1 PHE B 23 7295 6909 3468 534 -596 -424 C +ATOM 3155 CD2 PHE B 23 39.038 17.882 67.109 1.00 48.14 C +ANISOU 3155 CD2 PHE B 23 7701 6924 3664 368 -431 -625 C +ATOM 3156 CE1 PHE B 23 40.539 16.545 65.232 1.00 46.88 C +ANISOU 3156 CE1 PHE B 23 7206 6961 3646 475 -619 -432 C +ATOM 3157 CE2 PHE B 23 39.872 18.590 66.273 1.00 48.34 C +ANISOU 3157 CE2 PHE B 23 7593 6946 3826 306 -465 -628 C +ATOM 3158 CZ PHE B 23 40.633 17.921 65.336 1.00 47.83 C +ANISOU 3158 CZ PHE B 23 7357 6987 3826 358 -561 -529 C +ATOM 3159 N ARG B 24 38.894 17.037 70.618 1.00 52.28 N +ANISOU 3159 N ARG B 24 8660 7586 3615 245 -549 -796 N +ATOM 3160 CA ARG B 24 39.599 18.037 71.418 1.00 55.73 C +ANISOU 3160 CA ARG B 24 9189 8035 3951 60 -608 -958 C +ATOM 3161 C ARG B 24 40.505 17.404 72.483 1.00 56.96 C +ANISOU 3161 C ARG B 24 9404 8382 3857 -16 -841 -959 C +ATOM 3162 O ARG B 24 41.647 17.845 72.692 1.00 57.86 O +ANISOU 3162 O ARG B 24 9455 8591 3935 -148 -1014 -1018 O +ATOM 3163 CB ARG B 24 38.615 18.987 72.081 1.00 58.10 C +ANISOU 3163 CB ARG B 24 9693 8165 4217 -11 -381 -1109 C +ATOM 3164 CG ARG B 24 37.917 19.910 71.113 1.00 58.99 C +ANISOU 3164 CG ARG B 24 9734 8080 4599 33 -173 -1115 C +ATOM 3165 CD ARG B 24 37.036 20.916 71.842 1.00 62.17 C +ANISOU 3165 CD ARG B 24 10331 8294 4997 -37 66 -1274 C +ATOM 3166 NE ARG B 24 37.843 21.691 72.795 1.00 66.76 N +ANISOU 3166 NE ARG B 24 11054 8895 5416 -247 5 -1469 N +ATOM 3167 CZ ARG B 24 37.361 22.377 73.831 1.00 70.76 C +ANISOU 3167 CZ ARG B 24 11792 9288 5803 -362 171 -1654 C +ATOM 3168 NH1 ARG B 24 36.046 22.427 74.075 1.00 71.97 N +ANISOU 3168 NH1 ARG B 24 12053 9288 6004 -273 433 -1667 N +ATOM 3169 NH2 ARG B 24 38.194 23.033 74.638 1.00 73.23 N +ANISOU 3169 NH2 ARG B 24 12231 9641 5951 -577 86 -1836 N +ATOM 3170 N PHE B 25 39.990 16.356 73.119 1.00 56.55 N +ANISOU 3170 N PHE B 25 9458 8386 3643 64 -853 -877 N +ATOM 3171 CA PHE B 25 40.700 15.682 74.189 1.00 58.82 C +ANISOU 3171 CA PHE B 25 9822 8851 3676 4 -1071 -842 C +ATOM 3172 C PHE B 25 41.930 14.911 73.701 1.00 58.68 C +ANISOU 3172 C PHE B 25 9572 8990 3733 66 -1321 -697 C +ATOM 3173 O PHE B 25 42.968 14.914 74.358 1.00 60.06 O +ANISOU 3173 O PHE B 25 9726 9317 3777 -40 -1551 -700 O +ATOM 3174 CB PHE B 25 39.738 14.745 74.911 1.00 59.00 C +ANISOU 3174 CB PHE B 25 10021 8869 3528 87 -987 -770 C +ATOM 3175 CG PHE B 25 40.361 13.978 76.029 1.00 61.68 C +ANISOU 3175 CG PHE B 25 10459 9386 3590 38 -1207 -700 C +ATOM 3176 CD1 PHE B 25 40.950 14.650 77.097 1.00 64.54 C +ANISOU 3176 CD1 PHE B 25 10968 9842 3711 -168 -1331 -829 C +ATOM 3177 CD2 PHE B 25 40.359 12.580 76.033 1.00 61.47 C +ANISOU 3177 CD2 PHE B 25 10386 9432 3537 188 -1295 -499 C +ATOM 3178 CE1 PHE B 25 41.527 13.956 78.146 1.00 66.65 C +ANISOU 3178 CE1 PHE B 25 11329 10292 3700 -225 -1560 -743 C +ATOM 3179 CE2 PHE B 25 40.938 11.886 77.091 1.00 63.67 C +ANISOU 3179 CE2 PHE B 25 10756 9872 3561 147 -1509 -405 C +ATOM 3180 CZ PHE B 25 41.516 12.581 78.146 1.00 66.13 C +ANISOU 3180 CZ PHE B 25 11210 10296 3619 -59 -1651 -519 C +ATOM 3181 N ALA B 26 41.802 14.253 72.546 1.00 57.21 N +ANISOU 3181 N ALA B 26 9208 8766 3760 234 -1271 -569 N +ATOM 3182 CA ALA B 26 42.892 13.440 72.011 1.00 56.80 C +ANISOU 3182 CA ALA B 26 8932 8836 3812 316 -1458 -431 C +ATOM 3183 C ALA B 26 44.073 14.296 71.594 1.00 57.61 C +ANISOU 3183 C ALA B 26 8859 8994 4033 203 -1574 -496 C +ATOM 3184 O ALA B 26 45.237 13.886 71.748 1.00 58.65 O +ANISOU 3184 O ALA B 26 8839 9273 4171 194 -1792 -422 O +ATOM 3185 CB ALA B 26 42.403 12.629 70.836 1.00 54.26 C +ANISOU 3185 CB ALA B 26 8492 8440 3682 497 -1337 -316 C +ATOM 3186 N VAL B 27 43.759 15.481 71.065 1.00 57.20 N +ANISOU 3186 N VAL B 27 8819 8819 4093 120 -1422 -624 N +ATOM 3187 CA VAL B 27 44.768 16.444 70.634 1.00 58.32 C +ANISOU 3187 CA VAL B 27 8814 8983 4362 -7 -1491 -701 C +ATOM 3188 C VAL B 27 45.516 16.957 71.853 1.00 61.64 C +ANISOU 3188 C VAL B 27 9315 9516 4588 -204 -1678 -807 C +ATOM 3189 O VAL B 27 46.748 17.080 71.831 1.00 63.03 O +ANISOU 3189 O VAL B 27 9315 9818 4814 -288 -1871 -796 O +ATOM 3190 CB VAL B 27 44.115 17.615 69.857 1.00 57.36 C +ANISOU 3190 CB VAL B 27 8720 8674 4397 -49 -1264 -801 C +ATOM 3191 CG1 VAL B 27 45.073 18.778 69.660 1.00 58.57 C +ANISOU 3191 CG1 VAL B 27 8778 8825 4649 -223 -1315 -909 C +ATOM 3192 CG2 VAL B 27 43.610 17.122 68.505 1.00 55.10 C +ANISOU 3192 CG2 VAL B 27 8313 8317 4305 119 -1130 -679 C +ATOM 3193 N GLN B 28 44.756 17.240 72.910 1.00 63.13 N +ANISOU 3193 N GLN B 28 9767 9664 4555 -286 -1614 -910 N +ATOM 3194 CA GLN B 28 45.315 17.684 74.172 1.00 66.31 C +ANISOU 3194 CA GLN B 28 10304 10178 4713 -495 -1782 -1025 C +ATOM 3195 C GLN B 28 46.274 16.657 74.780 1.00 68.18 C +ANISOU 3195 C GLN B 28 10443 10647 4815 -478 -2089 -877 C +ATOM 3196 O GLN B 28 47.310 17.036 75.325 1.00 70.39 O +ANISOU 3196 O GLN B 28 10665 11069 5010 -650 -2316 -923 O +ATOM 3197 CB GLN B 28 44.190 18.000 75.142 1.00 67.04 C +ANISOU 3197 CB GLN B 28 10716 10174 4580 -560 -1614 -1152 C +ATOM 3198 CG GLN B 28 44.672 18.542 76.472 1.00 70.67 C +ANISOU 3198 CG GLN B 28 11364 10740 4746 -808 -1759 -1303 C +ATOM 3199 CD GLN B 28 43.543 18.652 77.476 1.00 71.77 C +ANISOU 3199 CD GLN B 28 11835 10795 4636 -857 -1574 -1413 C +ATOM 3200 OE1 GLN B 28 43.631 18.149 78.596 1.00 73.78 O +ANISOU 3200 OE1 GLN B 28 12260 11191 4581 -933 -1710 -1398 O +ATOM 3201 NE2 GLN B 28 42.456 19.285 77.060 1.00 70.70 N +ANISOU 3201 NE2 GLN B 28 11788 10428 4643 -806 -1256 -1511 N +ATOM 3202 N LEU B 29 45.921 15.371 74.691 1.00 67.97 N +ANISOU 3202 N LEU B 29 10394 10652 4779 -276 -2099 -692 N +ATOM 3203 CA LEU B 29 46.826 14.284 75.109 1.00 70.00 C +ANISOU 3203 CA LEU B 29 10522 11103 4971 -212 -2376 -505 C +ATOM 3204 C LEU B 29 48.076 14.158 74.213 1.00 70.89 C +ANISOU 3204 C LEU B 29 10288 11295 5351 -166 -2518 -415 C +ATOM 3205 O LEU B 29 49.167 13.827 74.702 1.00 73.60 O +ANISOU 3205 O LEU B 29 10489 11819 5655 -212 -2795 -322 O +ATOM 3206 CB LEU B 29 46.094 12.944 75.147 1.00 68.60 C +ANISOU 3206 CB LEU B 29 10408 10900 4756 0 -2313 -329 C +ATOM 3207 CG LEU B 29 44.988 12.790 76.188 1.00 68.95 C +ANISOU 3207 CG LEU B 29 10777 10904 4516 -34 -2207 -369 C +ATOM 3208 CD1 LEU B 29 44.263 11.475 75.944 1.00 67.37 C +ANISOU 3208 CD1 LEU B 29 10593 10647 4357 186 -2110 -192 C +ATOM 3209 CD2 LEU B 29 45.536 12.844 77.606 1.00 72.60 C +ANISOU 3209 CD2 LEU B 29 11389 11546 4649 -207 -2449 -377 C +ATOM 3210 N TYR B 30 47.943 14.419 72.912 1.00 69.29 N +ANISOU 3210 N TYR B 30 9940 10964 5420 -81 -2332 -433 N +ATOM 3211 CA TYR B 30 49.132 14.463 72.066 1.00 70.30 C +ANISOU 3211 CA TYR B 30 9755 11158 5798 -67 -2429 -378 C +ATOM 3212 C TYR B 30 50.072 15.584 72.566 1.00 74.77 C +ANISOU 3212 C TYR B 30 10267 11817 6323 -319 -2594 -511 C +ATOM 3213 O TYR B 30 51.286 15.363 72.748 1.00 76.98 O +ANISOU 3213 O TYR B 30 10325 12262 6660 -362 -2836 -432 O +ATOM 3214 CB TYR B 30 48.800 14.616 70.565 1.00 67.11 C +ANISOU 3214 CB TYR B 30 9235 10603 5659 42 -2186 -382 C +ATOM 3215 CG TYR B 30 50.050 14.945 69.785 1.00 67.00 C +ANISOU 3215 CG TYR B 30 8926 10650 5879 0 -2258 -368 C +ATOM 3216 CD1 TYR B 30 50.983 13.968 69.481 1.00 67.22 C +ANISOU 3216 CD1 TYR B 30 8705 10786 6049 126 -2383 -210 C +ATOM 3217 CD2 TYR B 30 50.341 16.255 69.448 1.00 67.34 C +ANISOU 3217 CD2 TYR B 30 8940 10641 6005 -175 -2200 -513 C +ATOM 3218 CE1 TYR B 30 52.157 14.284 68.827 1.00 68.39 C +ANISOU 3218 CE1 TYR B 30 8570 10993 6420 80 -2437 -200 C +ATOM 3219 CE2 TYR B 30 51.520 16.593 68.816 1.00 68.51 C +ANISOU 3219 CE2 TYR B 30 8817 10850 6361 -235 -2265 -503 C +ATOM 3220 CZ TYR B 30 52.428 15.603 68.488 1.00 69.01 C +ANISOU 3220 CZ TYR B 30 8622 11028 6568 -106 -2379 -348 C +ATOM 3221 OH TYR B 30 53.609 15.950 67.842 1.00 70.74 O +ANISOU 3221 OH TYR B 30 8555 11306 7016 -167 -2420 -339 O +ATOM 3222 N ASN B 31 49.498 16.757 72.839 1.00 77.24 N +ANISOU 3222 N ASN B 31 10782 12023 6543 -489 -2465 -711 N +ATOM 3223 CA ASN B 31 50.277 17.963 73.167 1.00 81.78 C +ANISOU 3223 CA ASN B 31 11326 12638 7106 -749 -2567 -873 C +ATOM 3224 C ASN B 31 50.862 18.037 74.573 1.00 87.94 C +ANISOU 3224 C ASN B 31 12202 13605 7605 -947 -2848 -918 C +ATOM 3225 O ASN B 31 51.816 18.773 74.790 1.00 90.94 O +ANISOU 3225 O ASN B 31 12472 14074 8004 -1156 -3009 -1008 O +ATOM 3226 CB ASN B 31 49.438 19.225 72.910 1.00 80.38 C +ANISOU 3226 CB ASN B 31 11337 12243 6957 -857 -2299 -1075 C +ATOM 3227 CG ASN B 31 49.339 19.559 71.438 1.00 77.48 C +ANISOU 3227 CG ASN B 31 10807 11730 6900 -755 -2094 -1046 C +ATOM 3228 OD1 ASN B 31 50.319 19.421 70.707 1.00 77.24 O +ANISOU 3228 OD1 ASN B 31 10506 11775 7066 -735 -2178 -966 O +ATOM 3229 ND2 ASN B 31 48.171 20.017 70.994 1.00 74.65 N +ANISOU 3229 ND2 ASN B 31 10606 11168 6588 -696 -1823 -1103 N +ATOM 3230 N THR B 32 50.293 17.301 75.521 1.00 92.05 N +ANISOU 3230 N THR B 32 12928 14188 7858 -898 -2909 -856 N +ATOM 3231 CA THR B 32 50.757 17.349 76.903 1.00 97.47 C +ANISOU 3231 CA THR B 32 13746 15062 8224 -1098 -3178 -891 C +ATOM 3232 C THR B 32 51.563 16.112 77.286 1.00101.27 C +ANISOU 3232 C THR B 32 14046 15766 8666 -987 -3487 -634 C +ATOM 3233 O THR B 32 51.758 15.840 78.473 1.00106.43 O +ANISOU 3233 O THR B 32 14836 16586 9014 -1101 -3717 -596 O +ATOM 3234 CB THR B 32 49.568 17.457 77.866 1.00 98.20 C +ANISOU 3234 CB THR B 32 14235 15080 7995 -1157 -3033 -1003 C +ATOM 3235 OG1 THR B 32 48.720 16.314 77.695 1.00 95.09 O +ANISOU 3235 OG1 THR B 32 13897 14632 7600 -898 -2914 -831 O +ATOM 3236 CG2 THR B 32 48.786 18.746 77.617 1.00 97.83 C +ANISOU 3236 CG2 THR B 32 14372 14804 7995 -1275 -2727 -1261 C +ATOM 3237 N ASN B 33 52.033 15.366 76.292 1.00101.70 N +ANISOU 3237 N ASN B 33 13799 15818 9024 -768 -3487 -453 N +ATOM 3238 CA ASN B 33 52.813 14.160 76.547 1.00104.59 C +ANISOU 3238 CA ASN B 33 13958 16360 9419 -628 -3750 -192 C +ATOM 3239 C ASN B 33 54.144 14.521 77.207 1.00109.13 C +ANISOU 3239 C ASN B 33 14351 17171 9942 -837 -4115 -174 C +ATOM 3240 O ASN B 33 54.882 15.371 76.714 1.00110.52 O +ANISOU 3240 O ASN B 33 14334 17357 10302 -975 -4138 -283 O +ATOM 3241 CB ASN B 33 53.063 13.399 75.239 1.00103.52 C +ANISOU 3241 CB ASN B 33 13534 16142 9656 -363 -3625 -40 C +ATOM 3242 CG ASN B 33 53.649 12.010 75.464 1.00105.30 C +ANISOU 3242 CG ASN B 33 13578 16491 9941 -165 -3828 242 C +ATOM 3243 OD1 ASN B 33 54.173 11.704 76.537 1.00108.85 O +ANISOU 3243 OD1 ASN B 33 14035 17129 10194 -242 -4129 352 O +ATOM 3244 ND2 ASN B 33 53.563 11.161 74.443 1.00103.62 N +ANISOU 3244 ND2 ASN B 33 13204 16167 9998 87 -3661 365 N +ATOM 3245 N ASN B 35 56.737 12.795 77.218 1.00154.00 N +ANISOU 3245 N ASN B 35 19271 23246 15995 -628 -4738 354 N +ATOM 3246 CA ASN B 35 57.812 12.358 76.327 1.00153.35 C +ANISOU 3246 CA ASN B 35 18746 23199 16322 -478 -4791 509 C +ATOM 3247 C ASN B 35 58.002 13.399 75.220 1.00151.71 C +ANISOU 3247 C ASN B 35 18409 22864 16369 -569 -4562 303 C +ATOM 3248 O ASN B 35 57.096 13.614 74.407 1.00149.32 O +ANISOU 3248 O ASN B 35 18258 22346 16129 -484 -4220 185 O +ATOM 3249 CB ASN B 35 57.482 10.977 75.733 1.00149.35 C +ANISOU 3249 CB ASN B 35 18161 22579 16004 -123 -4641 729 C +ATOM 3250 CG ASN B 35 58.674 10.309 75.066 1.00148.87 C +ANISOU 3250 CG ASN B 35 17644 22577 16340 48 -4734 932 C +ATOM 3251 OD1 ASN B 35 59.746 10.904 74.924 1.00149.56 O +ANISOU 3251 OD1 ASN B 35 17443 22785 16597 -87 -4889 908 O +ATOM 3252 ND2 ASN B 35 58.480 9.076 74.622 1.00145.33 N +ANISOU 3252 ND2 ASN B 35 17125 22029 16062 346 -4615 1123 N +ATOM 3253 N THR B 36 59.175 14.037 75.204 1.00152.30 N +ANISOU 3253 N THR B 36 18202 23078 16588 -748 -4759 274 N +ATOM 3254 CA THR B 36 59.525 15.043 74.187 1.00149.14 C +ANISOU 3254 CA THR B 36 17646 22573 16444 -855 -4566 101 C +ATOM 3255 C THR B 36 59.690 14.466 72.760 1.00147.11 C +ANISOU 3255 C THR B 36 17137 22180 16578 -592 -4305 199 C +ATOM 3256 O THR B 36 59.419 15.149 71.763 1.00145.41 O +ANISOU 3256 O THR B 36 16935 21801 16511 -616 -4021 54 O +ATOM 3257 CB THR B 36 60.813 15.820 74.578 1.00150.95 C +ANISOU 3257 CB THR B 36 17612 22999 16742 -1130 -4861 56 C +ATOM 3258 OG1 THR B 36 61.075 16.845 73.613 1.00148.51 O +ANISOU 3258 OG1 THR B 36 17189 22568 16669 -1249 -4647 -118 O +ATOM 3259 CG2 THR B 36 62.049 14.900 74.679 1.00153.12 C +ANISOU 3259 CG2 THR B 36 17458 23476 17243 -1006 -5152 333 C +ATOM 3260 N THR B 37 60.145 13.217 72.678 1.00147.76 N +ANISOU 3260 N THR B 37 16997 22325 16819 -348 -4397 447 N +ATOM 3261 CA THR B 37 60.387 12.531 71.403 1.00144.84 C +ANISOU 3261 CA THR B 37 16384 21836 16812 -95 -4156 547 C +ATOM 3262 C THR B 37 59.108 12.251 70.613 1.00138.75 C +ANISOU 3262 C THR B 37 15883 20831 16004 66 -3788 475 C +ATOM 3263 O THR B 37 59.112 12.288 69.380 1.00137.58 O +ANISOU 3263 O THR B 37 15628 20551 16094 157 -3516 435 O +ATOM 3264 CB THR B 37 61.086 11.178 71.647 1.00147.66 C +ANISOU 3264 CB THR B 37 16474 22295 17333 139 -4337 836 C +ATOM 3265 OG1 THR B 37 62.197 11.365 72.533 1.00151.56 O +ANISOU 3265 OG1 THR B 37 16726 23032 17826 -10 -4730 936 O +ATOM 3266 CG2 THR B 37 61.569 10.569 70.330 1.00146.43 C +ANISOU 3266 CG2 THR B 37 16021 22025 17589 366 -4087 916 C +ATOM 3267 N GLU B 38 58.027 11.952 71.331 1.00135.28 N +ANISOU 3267 N GLU B 38 15789 20350 15260 94 -3786 467 N +ATOM 3268 CA GLU B 38 56.720 11.696 70.724 1.00128.79 C +ANISOU 3268 CA GLU B 38 15235 19322 14376 227 -3469 403 C +ATOM 3269 C GLU B 38 55.896 12.982 70.475 1.00122.50 C +ANISOU 3269 C GLU B 38 14687 18404 13453 42 -3276 158 C +ATOM 3270 O GLU B 38 54.770 12.894 69.976 1.00117.72 O +ANISOU 3270 O GLU B 38 14297 17633 12797 131 -3023 102 O +ATOM 3271 CB GLU B 38 55.924 10.703 71.588 1.00128.95 C +ANISOU 3271 CB GLU B 38 15491 19342 14159 356 -3534 526 C +ATOM 3272 N LYS B 39 56.464 14.154 70.792 1.00118.89 N +ANISOU 3272 N LYS B 39 14187 18020 12965 -212 -3392 21 N +ATOM 3273 CA LYS B 39 55.778 15.441 70.606 1.00113.73 C +ANISOU 3273 CA LYS B 39 13754 17235 12221 -396 -3212 -206 C +ATOM 3274 C LYS B 39 56.705 16.553 70.047 1.00111.51 C +ANISOU 3274 C LYS B 39 13259 16965 12144 -589 -3207 -317 C +ATOM 3275 O LYS B 39 56.770 17.656 70.602 1.00110.56 O +ANISOU 3275 O LYS B 39 13250 16854 11902 -841 -3272 -484 O +ATOM 3276 CB LYS B 39 55.147 15.869 71.936 1.00114.35 C +ANISOU 3276 CB LYS B 39 14153 17351 11941 -561 -3332 -312 C +ATOM 3277 N PRO B 40 57.404 16.278 68.918 1.00107.90 N +ANISOU 3277 N PRO B 40 12504 16491 11999 -478 -3102 -235 N +ATOM 3278 CA PRO B 40 58.383 17.237 68.375 1.00106.13 C +ANISOU 3278 CA PRO B 40 12044 16288 11991 -657 -3095 -315 C +ATOM 3279 C PRO B 40 57.800 18.466 67.659 1.00100.62 C +ANISOU 3279 C PRO B 40 11508 15403 11320 -789 -2832 -493 C +ATOM 3280 O PRO B 40 58.574 19.327 67.246 1.00100.55 O +ANISOU 3280 O PRO B 40 11326 15396 11480 -956 -2816 -565 O +ATOM 3281 CB PRO B 40 59.181 16.391 67.376 1.00106.52 C +ANISOU 3281 CB PRO B 40 11752 16362 12356 -462 -3020 -157 C +ATOM 3282 CG PRO B 40 58.194 15.394 66.882 1.00104.26 C +ANISOU 3282 CG PRO B 40 11626 15957 12029 -203 -2822 -77 C +ATOM 3283 CD PRO B 40 57.270 15.094 68.042 1.00105.29 C +ANISOU 3283 CD PRO B 40 12064 16104 11838 -194 -2947 -80 C +ATOM 3284 N PHE B 41 56.473 18.529 67.493 1.00 94.01 N +ANISOU 3284 N PHE B 41 10977 14403 10337 -710 -2628 -547 N +ATOM 3285 CA PHE B 41 55.779 19.718 66.967 1.00 88.78 C +ANISOU 3285 CA PHE B 41 10498 13551 9681 -827 -2395 -698 C +ATOM 3286 C PHE B 41 54.479 19.891 67.739 1.00 85.07 C +ANISOU 3286 C PHE B 41 10391 12985 8944 -831 -2344 -784 C +ATOM 3287 O PHE B 41 53.935 18.916 68.286 1.00 83.37 O +ANISOU 3287 O PHE B 41 10287 12818 8572 -685 -2407 -701 O +ATOM 3288 CB PHE B 41 55.465 19.553 65.480 1.00 85.33 C +ANISOU 3288 CB PHE B 41 9999 12985 9436 -673 -2116 -633 C +ATOM 3289 CG PHE B 41 54.654 18.329 65.182 1.00 82.25 C +ANISOU 3289 CG PHE B 41 9695 12567 8989 -416 -2029 -513 C +ATOM 3290 CD1 PHE B 41 55.269 17.113 64.981 1.00 82.66 C +ANISOU 3290 CD1 PHE B 41 9538 12725 9142 -246 -2100 -368 C +ATOM 3291 CD2 PHE B 41 53.270 18.388 65.162 1.00 79.86 C +ANISOU 3291 CD2 PHE B 41 9676 12126 8539 -350 -1875 -548 C +ATOM 3292 CE1 PHE B 41 54.523 15.975 64.724 1.00 81.30 C +ANISOU 3292 CE1 PHE B 41 9457 12511 8922 -23 -2010 -270 C +ATOM 3293 CE2 PHE B 41 52.513 17.258 64.906 1.00 78.17 C +ANISOU 3293 CE2 PHE B 41 9538 11887 8274 -134 -1800 -445 C +ATOM 3294 CZ PHE B 41 53.140 16.042 64.693 1.00 78.84 C +ANISOU 3294 CZ PHE B 41 9433 12071 8452 23 -1867 -311 C +ATOM 3295 N HIS B 42 53.982 21.125 67.784 1.00 83.25 N +ANISOU 3295 N HIS B 42 10344 12608 8679 -997 -2213 -947 N +ATOM 3296 CA HIS B 42 52.689 21.387 68.398 1.00 81.74 C +ANISOU 3296 CA HIS B 42 10488 12291 8278 -995 -2106 -1039 C +ATOM 3297 C HIS B 42 51.550 21.096 67.397 1.00 77.71 C +ANISOU 3297 C HIS B 42 10068 11615 7840 -787 -1839 -964 C +ATOM 3298 O HIS B 42 51.582 21.564 66.256 1.00 74.83 O +ANISOU 3298 O HIS B 42 9613 11147 7671 -771 -1670 -943 O +ATOM 3299 CB HIS B 42 52.611 22.831 68.898 1.00 84.00 C +ANISOU 3299 CB HIS B 42 10934 12465 8516 -1254 -2058 -1249 C +ATOM 3300 CG HIS B 42 51.427 23.097 69.783 1.00 84.86 C +ANISOU 3300 CG HIS B 42 11382 12464 8394 -1278 -1968 -1365 C +ATOM 3301 ND1 HIS B 42 51.435 22.843 71.141 1.00 87.73 N +ANISOU 3301 ND1 HIS B 42 11900 12951 8481 -1376 -2153 -1431 N +ATOM 3302 CD2 HIS B 42 50.195 23.591 69.504 1.00 83.48 C +ANISOU 3302 CD2 HIS B 42 11418 12070 8230 -1216 -1704 -1418 C +ATOM 3303 CE1 HIS B 42 50.263 23.169 71.659 1.00 86.74 C +ANISOU 3303 CE1 HIS B 42 12073 12680 8203 -1377 -1984 -1536 C +ATOM 3304 NE2 HIS B 42 49.492 23.625 70.688 1.00 84.44 N +ANISOU 3304 NE2 HIS B 42 11809 12177 8098 -1274 -1711 -1528 N +ATOM 3305 N LEU B 43 50.556 20.317 67.839 1.00 75.58 N +ANISOU 3305 N LEU B 43 9977 11333 7407 -641 -1811 -916 N +ATOM 3306 CA LEU B 43 49.362 19.998 67.038 1.00 72.03 C +ANISOU 3306 CA LEU B 43 9628 10740 6998 -460 -1584 -849 C +ATOM 3307 C LEU B 43 48.207 20.939 67.356 1.00 72.05 C +ANISOU 3307 C LEU B 43 9887 10558 6929 -525 -1408 -972 C +ATOM 3308 O LEU B 43 47.774 21.073 68.495 1.00 73.08 O +ANISOU 3308 O LEU B 43 10215 10687 6865 -596 -1447 -1067 O +ATOM 3309 CB LEU B 43 48.918 18.564 67.287 1.00 70.00 C +ANISOU 3309 CB LEU B 43 9401 10561 6634 -263 -1637 -720 C +ATOM 3310 CG LEU B 43 47.888 17.997 66.312 1.00 66.17 C +ANISOU 3310 CG LEU B 43 8957 9969 6216 -75 -1437 -628 C +ATOM 3311 CD1 LEU B 43 48.324 18.173 64.870 1.00 65.33 C +ANISOU 3311 CD1 LEU B 43 8664 9827 6330 -44 -1327 -573 C +ATOM 3312 CD2 LEU B 43 47.663 16.523 66.616 1.00 64.95 C +ANISOU 3312 CD2 LEU B 43 8808 9898 5972 96 -1510 -505 C +ATOM 3313 N ASN B 44 47.683 21.543 66.305 1.00 71.51 N +ANISOU 3313 N ASN B 44 9814 10331 7023 -490 -1203 -955 N +ATOM 3314 CA ASN B 44 46.820 22.698 66.389 1.00 72.47 C +ANISOU 3314 CA ASN B 44 10116 10250 7169 -566 -1020 -1062 C +ATOM 3315 C ASN B 44 45.601 22.416 65.517 1.00 69.13 C +ANISOU 3315 C ASN B 44 9740 9708 6819 -385 -831 -948 C +ATOM 3316 O ASN B 44 45.667 21.535 64.664 1.00 66.29 O +ANISOU 3316 O ASN B 44 9253 9422 6512 -248 -841 -810 O +ATOM 3317 CB ASN B 44 47.616 23.868 65.850 1.00 75.27 C +ANISOU 3317 CB ASN B 44 10368 10534 7698 -731 -982 -1126 C +ATOM 3318 CG ASN B 44 46.926 25.168 66.042 1.00 78.55 C +ANISOU 3318 CG ASN B 44 10959 10722 8161 -836 -802 -1250 C +ATOM 3319 OD1 ASN B 44 46.751 25.614 67.176 1.00 84.00 O +ANISOU 3319 OD1 ASN B 44 11823 11375 8716 -959 -818 -1408 O +ATOM 3320 ND2 ASN B 44 46.525 25.798 64.937 1.00 78.84 N +ANISOU 3320 ND2 ASN B 44 10962 10601 8393 -792 -620 -1177 N +ATOM 3321 N TYR B 45 44.491 23.116 65.721 1.00 68.52 N +ANISOU 3321 N TYR B 45 9836 9448 6747 -384 -659 -1004 N +ATOM 3322 CA TYR B 45 43.322 22.829 64.900 1.00 66.39 C +ANISOU 3322 CA TYR B 45 9585 9083 6555 -216 -505 -879 C +ATOM 3323 C TYR B 45 42.326 23.952 64.833 1.00 67.40 C +ANISOU 3323 C TYR B 45 9836 8980 6791 -234 -299 -921 C +ATOM 3324 O TYR B 45 42.226 24.760 65.741 1.00 68.28 O +ANISOU 3324 O TYR B 45 10088 8990 6866 -350 -244 -1075 O +ATOM 3325 CB TYR B 45 42.608 21.563 65.396 1.00 64.96 C +ANISOU 3325 CB TYR B 45 9474 8987 6219 -74 -544 -820 C +ATOM 3326 CG TYR B 45 42.032 21.670 66.794 1.00 65.07 C +ANISOU 3326 CG TYR B 45 9695 8964 6062 -121 -524 -944 C +ATOM 3327 CD1 TYR B 45 40.787 22.243 67.019 1.00 64.54 C +ANISOU 3327 CD1 TYR B 45 9775 8716 6029 -91 -324 -984 C +ATOM 3328 CD2 TYR B 45 42.729 21.185 67.886 1.00 66.43 C +ANISOU 3328 CD2 TYR B 45 9915 9286 6039 -196 -700 -1011 C +ATOM 3329 CE1 TYR B 45 40.255 22.336 68.300 1.00 65.96 C +ANISOU 3329 CE1 TYR B 45 10158 8858 6045 -141 -274 -1109 C +ATOM 3330 CE2 TYR B 45 42.203 21.253 69.178 1.00 67.35 C +ANISOU 3330 CE2 TYR B 45 10247 9381 5961 -255 -676 -1125 C +ATOM 3331 CZ TYR B 45 40.961 21.831 69.381 1.00 66.96 C +ANISOU 3331 CZ TYR B 45 10355 9143 5942 -230 -448 -1184 C +ATOM 3332 OH TYR B 45 40.436 21.932 70.645 1.00 67.70 O +ANISOU 3332 OH TYR B 45 10674 9207 5842 -296 -389 -1310 O +ATOM 3333 N HIS B 46 41.580 23.970 63.737 1.00 68.46 N +ANISOU 3333 N HIS B 46 9915 9033 7060 -117 -184 -777 N +ATOM 3334 CA HIS B 46 40.402 24.795 63.632 1.00 70.35 C +ANISOU 3334 CA HIS B 46 10249 9058 7419 -77 9 -763 C +ATOM 3335 C HIS B 46 39.209 23.948 63.183 1.00 66.69 C +ANISOU 3335 C HIS B 46 9777 8607 6953 100 59 -617 C +ATOM 3336 O HIS B 46 39.316 23.153 62.255 1.00 62.83 O +ANISOU 3336 O HIS B 46 9173 8234 6463 178 -8 -482 O +ATOM 3337 CB HIS B 46 40.633 25.961 62.674 1.00 74.45 C +ANISOU 3337 CB HIS B 46 10701 9434 8151 -137 106 -711 C +ATOM 3338 CG HIS B 46 39.562 27.001 62.758 1.00 79.62 C +ANISOU 3338 CG HIS B 46 11454 9836 8959 -113 310 -715 C +ATOM 3339 ND1 HIS B 46 38.657 27.218 61.739 1.00 82.00 N +ANISOU 3339 ND1 HIS B 46 11697 10036 9420 4 412 -528 N +ATOM 3340 CD2 HIS B 46 39.208 27.839 63.766 1.00 82.48 C +ANISOU 3340 CD2 HIS B 46 11971 10024 9343 -186 437 -879 C +ATOM 3341 CE1 HIS B 46 37.813 28.171 62.104 1.00 83.79 C +ANISOU 3341 CE1 HIS B 46 12016 10028 9790 17 593 -561 C +ATOM 3342 NE2 HIS B 46 38.123 28.562 63.329 1.00 83.90 N +ANISOU 3342 NE2 HIS B 46 12168 9984 9726 -96 628 -785 N +ATOM 3343 N VAL B 47 38.078 24.152 63.854 1.00 66.08 N +ANISOU 3343 N VAL B 47 9824 8403 6879 151 190 -656 N +ATOM 3344 CA VAL B 47 36.881 23.355 63.650 1.00 63.99 C +ANISOU 3344 CA VAL B 47 9555 8147 6609 302 239 -538 C +ATOM 3345 C VAL B 47 35.803 24.176 62.949 1.00 64.77 C +ANISOU 3345 C VAL B 47 9622 8057 6929 372 404 -425 C +ATOM 3346 O VAL B 47 35.621 25.351 63.267 1.00 66.36 O +ANISOU 3346 O VAL B 47 9887 8066 7258 321 543 -499 O +ATOM 3347 CB VAL B 47 36.344 22.885 65.015 1.00 62.91 C +ANISOU 3347 CB VAL B 47 9573 8016 6314 313 275 -654 C +ATOM 3348 CG1 VAL B 47 34.956 22.278 64.895 1.00 62.09 C +ANISOU 3348 CG1 VAL B 47 9469 7876 6247 455 373 -546 C +ATOM 3349 CG2 VAL B 47 37.296 21.883 65.621 1.00 62.20 C +ANISOU 3349 CG2 VAL B 47 9497 8131 6003 273 86 -707 C +ATOM 3350 N ASP B 48 35.093 23.555 62.008 1.00 63.91 N +ANISOU 3350 N ASP B 48 9414 8000 6870 485 387 -245 N +ATOM 3351 CA ASP B 48 33.836 24.102 61.498 1.00 67.03 C +ANISOU 3351 CA ASP B 48 9767 8240 7459 575 522 -111 C +ATOM 3352 C ASP B 48 32.707 23.094 61.694 1.00 67.04 C +ANISOU 3352 C ASP B 48 9762 8297 7414 687 536 -45 C +ATOM 3353 O ASP B 48 32.919 21.879 61.645 1.00 65.65 O +ANISOU 3353 O ASP B 48 9571 8294 7075 706 416 -33 O +ATOM 3354 CB ASP B 48 33.944 24.501 60.020 1.00 68.45 C +ANISOU 3354 CB ASP B 48 9817 8420 7769 583 485 77 C +ATOM 3355 CG ASP B 48 34.882 25.682 59.794 1.00 72.49 C +ANISOU 3355 CG ASP B 48 10333 8829 8378 474 517 32 C +ATOM 3356 OD1 ASP B 48 34.852 26.661 60.581 1.00 77.10 O +ANISOU 3356 OD1 ASP B 48 11006 9230 9055 425 644 -92 O +ATOM 3357 OD2 ASP B 48 35.658 25.637 58.813 1.00 74.14 O +ANISOU 3357 OD2 ASP B 48 10461 9133 8573 426 428 115 O +ATOM 3358 N HIS B 49 31.509 23.614 61.946 1.00 70.22 N +ANISOU 3358 N HIS B 49 10170 8534 7976 760 696 -5 N +ATOM 3359 CA HIS B 49 30.322 22.786 62.063 1.00 70.80 C +ANISOU 3359 CA HIS B 49 10210 8638 8052 861 731 73 C +ATOM 3360 C HIS B 49 29.473 22.954 60.817 1.00 71.96 C +ANISOU 3360 C HIS B 49 10194 8762 8385 937 720 307 C +ATOM 3361 O HIS B 49 29.303 24.057 60.318 1.00 71.31 O +ANISOU 3361 O HIS B 49 10058 8534 8502 948 791 394 O +ATOM 3362 CB HIS B 49 29.535 23.171 63.313 1.00 72.35 C +ANISOU 3362 CB HIS B 49 10516 8675 8298 888 932 -48 C +ATOM 3363 CG HIS B 49 30.275 22.911 64.594 1.00 73.52 C +ANISOU 3363 CG HIS B 49 10844 8872 8219 798 928 -270 C +ATOM 3364 ND1 HIS B 49 30.251 21.689 65.242 1.00 72.20 N +ANISOU 3364 ND1 HIS B 49 10742 8851 7836 806 860 -313 N +ATOM 3365 CD2 HIS B 49 31.078 23.715 65.334 1.00 74.68 C +ANISOU 3365 CD2 HIS B 49 11120 8945 8311 686 970 -451 C +ATOM 3366 CE1 HIS B 49 30.991 21.761 66.334 1.00 73.58 C +ANISOU 3366 CE1 HIS B 49 11079 9050 7828 709 851 -496 C +ATOM 3367 NE2 HIS B 49 31.504 22.978 66.413 1.00 75.06 N +ANISOU 3367 NE2 HIS B 49 11306 9110 8101 627 912 -592 N +ATOM 3368 N LEU B 50 28.967 21.841 60.304 1.00 74.48 N +ANISOU 3368 N LEU B 50 10438 9228 8632 980 621 415 N +ATOM 3369 CA LEU B 50 28.016 21.842 59.201 1.00 76.21 C +ANISOU 3369 CA LEU B 50 10503 9456 8997 1040 587 640 C +ATOM 3370 C LEU B 50 26.617 21.633 59.772 1.00 81.91 C +ANISOU 3370 C LEU B 50 11182 10098 9843 1129 709 678 C +ATOM 3371 O LEU B 50 26.271 20.516 60.187 1.00 82.99 O +ANISOU 3371 O LEU B 50 11342 10336 9854 1140 685 636 O +ATOM 3372 CB LEU B 50 28.333 20.703 58.249 1.00 73.92 C +ANISOU 3372 CB LEU B 50 10162 9382 8540 1005 404 717 C +ATOM 3373 CG LEU B 50 29.774 20.660 57.761 1.00 73.25 C +ANISOU 3373 CG LEU B 50 10117 9398 8313 918 299 659 C +ATOM 3374 CD1 LEU B 50 30.051 19.370 56.990 1.00 72.07 C +ANISOU 3374 CD1 LEU B 50 9941 9449 7991 890 159 696 C +ATOM 3375 CD2 LEU B 50 30.065 21.910 56.951 1.00 73.83 C +ANISOU 3375 CD2 LEU B 50 10140 9381 8531 889 314 766 C +ATOM 3376 N ASP B 51 25.816 22.700 59.807 1.00 86.21 N +ANISOU 3376 N ASP B 51 11657 10448 10649 1197 855 761 N +ATOM 3377 CA ASP B 51 24.407 22.592 60.221 1.00 87.37 C +ANISOU 3377 CA ASP B 51 11718 10508 10970 1293 987 828 C +ATOM 3378 C ASP B 51 23.639 21.596 59.329 1.00 85.68 C +ANISOU 3378 C ASP B 51 11350 10462 10741 1311 836 1013 C +ATOM 3379 O ASP B 51 22.799 20.836 59.823 1.00 87.74 O +ANISOU 3379 O ASP B 51 11582 10750 11004 1345 888 1002 O +ATOM 3380 CB ASP B 51 23.720 23.962 60.206 1.00 91.54 C +ANISOU 3380 CB ASP B 51 12163 10789 11828 1375 1164 923 C +ATOM 3381 CG ASP B 51 24.293 24.916 61.242 1.00 94.60 C +ANISOU 3381 CG ASP B 51 12720 10981 12242 1346 1358 708 C +ATOM 3382 OD1 ASP B 51 25.529 24.896 61.458 1.00 96.49 O +ANISOU 3382 OD1 ASP B 51 13102 11287 12273 1241 1282 553 O +ATOM 3383 OD2 ASP B 51 23.510 25.692 61.833 1.00 96.39 O +ANISOU 3383 OD2 ASP B 51 12933 10983 12707 1422 1591 690 O +ATOM 3384 N SER B 52 23.952 21.578 58.028 1.00 80.41 N +ANISOU 3384 N SER B 52 10597 9910 10043 1271 653 1172 N +ATOM 3385 CA SER B 52 23.407 20.570 57.116 1.00 76.65 C +ANISOU 3385 CA SER B 52 10009 9620 9495 1247 484 1317 C +ATOM 3386 C SER B 52 24.493 19.978 56.205 1.00 71.86 C +ANISOU 3386 C SER B 52 9460 9199 8642 1143 298 1305 C +ATOM 3387 O SER B 52 25.644 20.398 56.245 1.00 70.71 O +ANISOU 3387 O SER B 52 9416 9041 8410 1099 297 1207 O +ATOM 3388 CB SER B 52 22.270 21.171 56.286 1.00 79.27 C +ANISOU 3388 CB SER B 52 10131 9904 10084 1307 457 1584 C +ATOM 3389 OG SER B 52 22.764 22.108 55.339 1.00 81.20 O +ANISOU 3389 OG SER B 52 10343 10122 10385 1287 384 1724 O +ATOM 3390 N SER B 53 24.108 19.003 55.383 1.00 67.23 N +ANISOU 3390 N SER B 53 8806 8784 7953 1095 152 1400 N +ATOM 3391 CA SER B 53 25.017 18.376 54.442 1.00 63.36 C +ANISOU 3391 CA SER B 53 8370 8466 7238 994 1 1390 C +ATOM 3392 C SER B 53 24.728 18.807 52.982 1.00 63.77 C +ANISOU 3392 C SER B 53 8310 8595 7322 945 -133 1623 C +ATOM 3393 O SER B 53 25.258 18.192 52.037 1.00 63.99 O +ANISOU 3393 O SER B 53 8374 8784 7155 846 -257 1636 O +ATOM 3394 CB SER B 53 24.956 16.857 54.597 1.00 62.05 C +ANISOU 3394 CB SER B 53 8252 8434 6888 951 -51 1290 C +ATOM 3395 OG SER B 53 25.346 16.446 55.907 1.00 59.32 O +ANISOU 3395 OG SER B 53 8024 8030 6483 990 55 1094 O +ATOM 3396 N ASN B 54 23.920 19.874 52.810 1.00 61.38 N +ANISOU 3396 N ASN B 54 7882 8173 7266 1013 -100 1809 N +ATOM 3397 CA ASN B 54 23.814 20.618 51.545 1.00 59.26 C +ANISOU 3397 CA ASN B 54 7524 7938 7050 979 -214 2052 C +ATOM 3398 C ASN B 54 25.196 21.046 50.999 1.00 55.81 C +ANISOU 3398 C ASN B 54 7206 7529 6469 902 -234 2004 C +ATOM 3399 O ASN B 54 26.121 21.414 51.733 1.00 54.46 O +ANISOU 3399 O ASN B 54 7142 7259 6290 915 -121 1827 O +ATOM 3400 CB ASN B 54 22.843 21.813 51.667 1.00 62.17 C +ANISOU 3400 CB ASN B 54 7743 8123 7754 1095 -138 2252 C +ATOM 3401 CG ASN B 54 23.534 23.145 51.932 1.00 62.83 C +ANISOU 3401 CG ASN B 54 7886 8007 7979 1140 -7 2238 C +ATOM 3402 OD1 ASN B 54 24.294 23.663 51.116 1.00 61.99 O +ANISOU 3402 OD1 ASN B 54 7822 7928 7804 1076 -70 2317 O +ATOM 3403 ND2 ASN B 54 23.249 23.712 53.084 1.00 63.86 N +ANISOU 3403 ND2 ASN B 54 8026 7927 8311 1241 190 2131 N +ATOM 3404 N SER B 55 25.336 20.979 49.685 1.00 53.83 N +ANISOU 3404 N SER B 55 6936 7423 6093 808 -381 2162 N +ATOM 3405 CA SER B 55 26.661 20.960 49.070 1.00 51.34 C +ANISOU 3405 CA SER B 55 6740 7190 5576 706 -403 2088 C +ATOM 3406 C SER B 55 27.416 22.269 49.223 1.00 50.38 C +ANISOU 3406 C SER B 55 6652 6902 5587 731 -299 2100 C +ATOM 3407 O SER B 55 28.624 22.261 49.251 1.00 48.65 O +ANISOU 3407 O SER B 55 6532 6701 5249 671 -258 1956 O +ATOM 3408 CB SER B 55 26.546 20.575 47.593 1.00 52.35 C +ANISOU 3408 CB SER B 55 6854 7517 5519 582 -570 2258 C +ATOM 3409 OG SER B 55 25.701 19.444 47.424 1.00 52.16 O +ANISOU 3409 OG SER B 55 6787 7631 5398 544 -671 2259 O +ATOM 3410 N PHE B 56 26.717 23.391 49.332 1.00 50.85 N +ANISOU 3410 N PHE B 56 6621 6791 5909 818 -246 2271 N +ATOM 3411 CA PHE B 56 27.372 24.682 49.518 1.00 50.99 C +ANISOU 3411 CA PHE B 56 6675 6616 6080 838 -127 2279 C +ATOM 3412 C PHE B 56 27.935 24.820 50.923 1.00 49.77 C +ANISOU 3412 C PHE B 56 6610 6317 5981 878 34 2000 C +ATOM 3413 O PHE B 56 29.072 25.215 51.112 1.00 49.39 O +ANISOU 3413 O PHE B 56 6653 6225 5885 819 93 1867 O +ATOM 3414 CB PHE B 56 26.393 25.818 49.288 1.00 52.72 C +ANISOU 3414 CB PHE B 56 6768 6663 6598 934 -98 2544 C +ATOM 3415 CG PHE B 56 26.995 27.171 49.505 1.00 53.78 C +ANISOU 3415 CG PHE B 56 6946 6565 6920 955 45 2552 C +ATOM 3416 CD1 PHE B 56 27.920 27.684 48.596 1.00 54.34 C +ANISOU 3416 CD1 PHE B 56 7076 6669 6901 854 9 2639 C +ATOM 3417 CD2 PHE B 56 26.659 27.939 50.617 1.00 54.21 C +ANISOU 3417 CD2 PHE B 56 6996 6360 7240 1062 235 2460 C +ATOM 3418 CE1 PHE B 56 28.489 28.926 48.796 1.00 55.21 C +ANISOU 3418 CE1 PHE B 56 7229 6553 7193 859 149 2642 C +ATOM 3419 CE2 PHE B 56 27.223 29.184 50.810 1.00 55.32 C +ANISOU 3419 CE2 PHE B 56 7189 6271 7556 1063 378 2451 C +ATOM 3420 CZ PHE B 56 28.136 29.676 49.901 1.00 55.83 C +ANISOU 3420 CZ PHE B 56 7303 6367 7541 962 330 2545 C +ATOM 3421 N SER B 57 27.110 24.528 51.908 1.00 49.46 N +ANISOU 3421 N SER B 57 6542 6206 6044 969 107 1919 N +ATOM 3422 CA SER B 57 27.539 24.536 53.277 1.00 48.93 C +ANISOU 3422 CA SER B 57 6576 6029 5985 993 248 1655 C +ATOM 3423 C SER B 57 28.826 23.711 53.392 1.00 46.97 C +ANISOU 3423 C SER B 57 6443 5937 5466 894 187 1451 C +ATOM 3424 O SER B 57 29.819 24.192 53.933 1.00 46.78 O +ANISOU 3424 O SER B 57 6505 5840 5429 852 256 1294 O +ATOM 3425 CB SER B 57 26.406 23.986 54.152 1.00 49.28 C +ANISOU 3425 CB SER B 57 6576 6039 6107 1085 311 1611 C +ATOM 3426 OG SER B 57 26.809 23.746 55.488 1.00 49.01 O +ANISOU 3426 OG SER B 57 6665 5945 6010 1090 428 1349 O +ATOM 3427 N VAL B 58 28.829 22.514 52.804 1.00 45.59 N +ANISOU 3427 N VAL B 58 6257 5972 5091 851 58 1464 N +ATOM 3428 CA VAL B 58 29.991 21.621 52.865 1.00 44.13 C +ANISOU 3428 CA VAL B 58 6161 5930 4675 776 9 1288 C +ATOM 3429 C VAL B 58 31.242 22.125 52.149 1.00 44.17 C +ANISOU 3429 C VAL B 58 6196 5966 4618 684 -6 1287 C +ATOM 3430 O VAL B 58 32.361 21.931 52.614 1.00 42.88 O +ANISOU 3430 O VAL B 58 6094 5828 4367 641 12 1113 O +ATOM 3431 CB VAL B 58 29.639 20.220 52.320 1.00 43.73 C +ANISOU 3431 CB VAL B 58 6096 6072 4446 749 -101 1305 C +ATOM 3432 CG1 VAL B 58 30.891 19.348 52.203 1.00 42.72 C +ANISOU 3432 CG1 VAL B 58 6044 6074 4111 680 -136 1150 C +ATOM 3433 CG2 VAL B 58 28.605 19.533 53.230 1.00 43.61 C +ANISOU 3433 CG2 VAL B 58 6065 6032 4470 825 -70 1255 C +ATOM 3434 N THR B 59 31.046 22.736 50.992 1.00 45.86 N +ANISOU 3434 N THR B 59 6360 6189 4874 649 -47 1496 N +ATOM 3435 CA THR B 59 32.142 23.185 50.155 1.00 46.44 C +ANISOU 3435 CA THR B 59 6460 6302 4880 551 -53 1527 C +ATOM 3436 C THR B 59 32.767 24.386 50.820 1.00 47.48 C +ANISOU 3436 C THR B 59 6619 6242 5178 550 62 1453 C +ATOM 3437 O THR B 59 33.985 24.474 50.938 1.00 46.84 O +ANISOU 3437 O THR B 59 6578 6180 5035 476 90 1320 O +ATOM 3438 CB THR B 59 31.618 23.549 48.744 1.00 47.91 C +ANISOU 3438 CB THR B 59 6597 6548 5057 509 -131 1801 C +ATOM 3439 OG1 THR B 59 30.988 22.404 48.178 1.00 47.44 O +ANISOU 3439 OG1 THR B 59 6521 6670 4832 487 -246 1848 O +ATOM 3440 CG2 THR B 59 32.731 24.000 47.803 1.00 48.45 C +ANISOU 3440 CG2 THR B 59 6705 6663 5038 395 -120 1846 C +ATOM 3441 N ASN B 60 31.914 25.298 51.275 1.00 49.54 N +ANISOU 3441 N ASN B 60 6850 6311 5662 629 138 1534 N +ATOM 3442 CA ASN B 60 32.353 26.505 51.978 1.00 51.30 C +ANISOU 3442 CA ASN B 60 7111 6313 6065 625 273 1453 C +ATOM 3443 C ASN B 60 33.178 26.126 53.194 1.00 50.58 C +ANISOU 3443 C ASN B 60 7101 6228 5887 593 312 1161 C +ATOM 3444 O ASN B 60 34.227 26.701 53.420 1.00 51.36 O +ANISOU 3444 O ASN B 60 7241 6271 5999 510 357 1049 O +ATOM 3445 CB ASN B 60 31.155 27.353 52.410 1.00 53.30 C +ANISOU 3445 CB ASN B 60 7321 6346 6581 737 374 1561 C +ATOM 3446 CG ASN B 60 31.442 28.846 52.365 1.00 55.96 C +ANISOU 3446 CG ASN B 60 7674 6442 7145 721 500 1621 C +ATOM 3447 OD1 ASN B 60 32.320 29.304 51.638 1.00 57.77 O +ANISOU 3447 OD1 ASN B 60 7919 6686 7341 626 484 1676 O +ATOM 3448 ND2 ASN B 60 30.666 29.621 53.111 1.00 57.82 N +ANISOU 3448 ND2 ASN B 60 7903 6440 7625 813 645 1617 N +ATOM 3449 N ALA B 61 32.738 25.131 53.954 1.00 49.23 N +ANISOU 3449 N ALA B 61 6949 6136 5618 648 285 1047 N +ATOM 3450 CA ALA B 61 33.487 24.709 55.136 1.00 48.85 C +ANISOU 3450 CA ALA B 61 6982 6111 5465 618 300 794 C +ATOM 3451 C ALA B 61 34.838 24.137 54.767 1.00 48.46 C +ANISOU 3451 C ALA B 61 6935 6227 5249 526 212 712 C +ATOM 3452 O ALA B 61 35.847 24.543 55.317 1.00 48.57 O +ANISOU 3452 O ALA B 61 6984 6209 5260 453 233 567 O +ATOM 3453 CB ALA B 61 32.700 23.691 55.946 1.00 47.69 C +ANISOU 3453 CB ALA B 61 6859 6021 5238 696 288 722 C +ATOM 3454 N PHE B 62 34.848 23.200 53.831 1.00 48.68 N +ANISOU 3454 N PHE B 62 6920 6427 5146 524 122 800 N +ATOM 3455 CA PHE B 62 36.092 22.603 53.366 1.00 49.24 C +ANISOU 3455 CA PHE B 62 6979 6649 5079 449 65 733 C +ATOM 3456 C PHE B 62 37.096 23.628 52.867 1.00 51.81 C +ANISOU 3456 C PHE B 62 7286 6920 5480 350 109 750 C +ATOM 3457 O PHE B 62 38.271 23.550 53.188 1.00 51.51 O +ANISOU 3457 O PHE B 62 7238 6927 5404 285 101 616 O +ATOM 3458 CB PHE B 62 35.819 21.613 52.232 1.00 48.36 C +ANISOU 3458 CB PHE B 62 6839 6701 4834 448 -3 844 C +ATOM 3459 CG PHE B 62 37.041 20.889 51.770 1.00 47.31 C +ANISOU 3459 CG PHE B 62 6693 6709 4571 385 -28 763 C +ATOM 3460 CD1 PHE B 62 37.303 19.639 52.248 1.00 46.46 C +ANISOU 3460 CD1 PHE B 62 6596 6702 4351 422 -68 644 C +ATOM 3461 CD2 PHE B 62 37.923 21.459 50.869 1.00 48.44 C +ANISOU 3461 CD2 PHE B 62 6810 6873 4721 293 4 814 C +ATOM 3462 CE1 PHE B 62 38.435 18.944 51.866 1.00 46.23 C +ANISOU 3462 CE1 PHE B 62 6540 6787 4238 382 -73 570 C +ATOM 3463 CE2 PHE B 62 39.057 20.776 50.469 1.00 48.27 C +ANISOU 3463 CE2 PHE B 62 6762 6975 4603 241 7 733 C +ATOM 3464 CZ PHE B 62 39.320 19.519 50.980 1.00 47.10 C +ANISOU 3464 CZ PHE B 62 6613 6919 4364 292 -29 609 C +ATOM 3465 N CYS B 63 36.631 24.570 52.057 1.00 55.54 N +ANISOU 3465 N CYS B 63 7741 7297 6063 337 151 929 N +ATOM 3466 CA CYS B 63 37.526 25.540 51.451 1.00 59.52 C +ANISOU 3466 CA CYS B 63 8231 7743 6641 236 204 975 C +ATOM 3467 C CYS B 63 38.058 26.556 52.443 1.00 60.01 C +ANISOU 3467 C CYS B 63 8322 7630 6847 191 285 834 C +ATOM 3468 O CYS B 63 39.197 26.991 52.327 1.00 60.87 O +ANISOU 3468 O CYS B 63 8414 7737 6975 84 310 768 O +ATOM 3469 CB CYS B 63 36.841 26.259 50.278 1.00 64.51 C +ANISOU 3469 CB CYS B 63 8845 8318 7347 235 220 1238 C +ATOM 3470 SG CYS B 63 36.743 25.217 48.792 1.00 69.01 S +ANISOU 3470 SG CYS B 63 9398 9130 7691 199 125 1387 S +ATOM 3471 N SER B 64 37.248 26.939 53.421 1.00 59.98 N +ANISOU 3471 N SER B 64 8364 7477 6947 259 336 779 N +ATOM 3472 CA SER B 64 37.708 27.881 54.430 1.00 60.99 C +ANISOU 3472 CA SER B 64 8547 7433 7193 199 422 615 C +ATOM 3473 C SER B 64 38.883 27.257 55.167 1.00 60.28 C +ANISOU 3473 C SER B 64 8462 7478 6964 120 350 398 C +ATOM 3474 O SER B 64 39.846 27.936 55.491 1.00 61.77 O +ANISOU 3474 O SER B 64 8655 7609 7205 3 376 285 O +ATOM 3475 CB SER B 64 36.598 28.243 55.409 1.00 61.86 C +ANISOU 3475 CB SER B 64 8719 7371 7412 287 510 569 C +ATOM 3476 OG SER B 64 36.362 27.182 56.309 1.00 61.97 O +ANISOU 3476 OG SER B 64 8769 7501 7274 338 452 433 O +ATOM 3477 N GLN B 65 38.818 25.951 55.407 1.00 58.03 N +ANISOU 3477 N GLN B 65 8166 7372 6509 180 252 351 N +ATOM 3478 CA GLN B 65 39.914 25.255 56.066 1.00 57.98 C +ANISOU 3478 CA GLN B 65 8144 7506 6379 126 165 181 C +ATOM 3479 C GLN B 65 41.083 25.007 55.155 1.00 57.23 C +ANISOU 3479 C GLN B 65 7952 7541 6251 51 125 213 C +ATOM 3480 O GLN B 65 42.219 25.064 55.589 1.00 57.67 O +ANISOU 3480 O GLN B 65 7964 7646 6301 -37 87 89 O +ATOM 3481 CB GLN B 65 39.435 23.960 56.688 1.00 57.51 C +ANISOU 3481 CB GLN B 65 8111 7566 6171 223 89 132 C +ATOM 3482 CG GLN B 65 38.631 24.257 57.943 1.00 58.91 C +ANISOU 3482 CG GLN B 65 8395 7621 6365 260 140 32 C +ATOM 3483 CD GLN B 65 38.171 23.009 58.644 1.00 59.21 C +ANISOU 3483 CD GLN B 65 8473 7769 6254 346 77 -13 C +ATOM 3484 OE1 GLN B 65 38.578 21.912 58.288 1.00 60.45 O +ANISOU 3484 OE1 GLN B 65 8577 8087 6302 375 -13 10 O +ATOM 3485 NE2 GLN B 65 37.360 23.165 59.675 1.00 60.93 N +ANISOU 3485 NE2 GLN B 65 8790 7889 6471 383 141 -86 N +ATOM 3486 N PHE B 66 40.814 24.747 53.886 1.00 56.23 N +ANISOU 3486 N PHE B 66 7788 7474 6104 76 139 379 N +ATOM 3487 CA PHE B 66 41.887 24.609 52.922 1.00 55.57 C +ANISOU 3487 CA PHE B 66 7622 7496 5994 -2 143 413 C +ATOM 3488 C PHE B 66 42.687 25.897 52.844 1.00 57.43 C +ANISOU 3488 C PHE B 66 7834 7613 6373 -131 214 396 C +ATOM 3489 O PHE B 66 43.902 25.862 52.776 1.00 57.77 O +ANISOU 3489 O PHE B 66 7797 7728 6423 -221 207 320 O +ATOM 3490 CB PHE B 66 41.336 24.224 51.561 1.00 54.24 C +ANISOU 3490 CB PHE B 66 7452 7400 5755 25 158 597 C +ATOM 3491 CG PHE B 66 42.381 24.072 50.518 1.00 53.73 C +ANISOU 3491 CG PHE B 66 7325 7442 5648 -61 194 630 C +ATOM 3492 CD1 PHE B 66 43.111 22.912 50.445 1.00 52.88 C +ANISOU 3492 CD1 PHE B 66 7162 7491 5436 -49 165 540 C +ATOM 3493 CD2 PHE B 66 42.644 25.090 49.625 1.00 54.82 C +ANISOU 3493 CD2 PHE B 66 7458 7509 5860 -154 276 754 C +ATOM 3494 CE1 PHE B 66 44.101 22.753 49.496 1.00 53.33 C +ANISOU 3494 CE1 PHE B 66 7155 7639 5467 -128 230 558 C +ATOM 3495 CE2 PHE B 66 43.620 24.934 48.645 1.00 55.32 C +ANISOU 3495 CE2 PHE B 66 7469 7674 5875 -244 334 782 C +ATOM 3496 CZ PHE B 66 44.348 23.757 48.582 1.00 54.52 C +ANISOU 3496 CZ PHE B 66 7309 7732 5673 -230 318 676 C +ATOM 3497 N SER B 67 41.999 27.031 52.885 1.00 59.67 N +ANISOU 3497 N SER B 67 8179 7702 6790 -138 291 467 N +ATOM 3498 CA SER B 67 42.656 28.342 52.812 1.00 62.50 C +ANISOU 3498 CA SER B 67 8531 7907 7307 -265 379 457 C +ATOM 3499 C SER B 67 43.540 28.678 54.007 1.00 64.33 C +ANISOU 3499 C SER B 67 8758 8102 7579 -366 358 229 C +ATOM 3500 O SER B 67 44.540 29.348 53.849 1.00 65.74 O +ANISOU 3500 O SER B 67 8886 8246 7844 -503 395 186 O +ATOM 3501 CB SER B 67 41.622 29.440 52.610 1.00 63.57 C +ANISOU 3501 CB SER B 67 8736 7816 7598 -229 477 597 C +ATOM 3502 OG SER B 67 41.106 29.341 51.306 1.00 64.27 O +ANISOU 3502 OG SER B 67 8808 7952 7659 -186 483 836 O +ATOM 3503 N ARG B 68 43.173 28.211 55.197 1.00 66.30 N +ANISOU 3503 N ARG B 68 9065 8368 7757 -312 295 86 N +ATOM 3504 CA ARG B 68 43.987 28.410 56.418 1.00 68.27 C +ANISOU 3504 CA ARG B 68 9323 8618 7996 -420 242 -134 C +ATOM 3505 C ARG B 68 45.351 27.731 56.355 1.00 67.02 C +ANISOU 3505 C ARG B 68 9030 8663 7771 -493 133 -201 C +ATOM 3506 O ARG B 68 46.239 28.067 57.123 1.00 67.85 O +ANISOU 3506 O ARG B 68 9104 8778 7896 -621 79 -353 O +ATOM 3507 CB ARG B 68 43.247 27.881 57.650 1.00 70.29 C +ANISOU 3507 CB ARG B 68 9681 8880 8143 -340 192 -249 C +ATOM 3508 CG ARG B 68 42.147 28.789 58.146 1.00 73.07 C +ANISOU 3508 CG ARG B 68 10167 8996 8599 -311 322 -264 C +ATOM 3509 CD ARG B 68 41.269 28.093 59.177 1.00 74.33 C +ANISOU 3509 CD ARG B 68 10423 9181 8636 -209 297 -344 C +ATOM 3510 NE ARG B 68 40.286 29.041 59.684 1.00 78.06 N +ANISOU 3510 NE ARG B 68 11016 9409 9234 -189 455 -376 N +ATOM 3511 CZ ARG B 68 40.528 29.977 60.608 1.00 82.15 C +ANISOU 3511 CZ ARG B 68 11638 9768 9806 -311 535 -560 C +ATOM 3512 NH1 ARG B 68 41.733 30.100 61.175 1.00 84.10 N +ANISOU 3512 NH1 ARG B 68 11882 10095 9976 -479 442 -729 N +ATOM 3513 NH2 ARG B 68 39.554 30.803 60.976 1.00 83.90 N +ANISOU 3513 NH2 ARG B 68 11965 9746 10166 -272 713 -579 N +ATOM 3514 N GLY B 69 45.492 26.748 55.470 1.00 64.67 N +ANISOU 3514 N GLY B 69 8648 8525 7398 -414 103 -91 N +ATOM 3515 CA GLY B 69 46.752 26.055 55.254 1.00 64.25 C +ANISOU 3515 CA GLY B 69 8445 8650 7316 -458 33 -130 C +ATOM 3516 C GLY B 69 46.899 24.770 56.049 1.00 63.07 C +ANISOU 3516 C GLY B 69 8266 8662 7035 -368 -103 -208 C +ATOM 3517 O GLY B 69 48.028 24.358 56.332 1.00 65.71 O +ANISOU 3517 O GLY B 69 8469 9120 7375 -417 -188 -277 O +ATOM 3518 N VAL B 70 45.787 24.122 56.393 1.00 59.86 N +ANISOU 3518 N VAL B 70 7967 8253 6522 -236 -125 -183 N +ATOM 3519 CA VAL B 70 45.839 22.881 57.152 1.00 58.24 C +ANISOU 3519 CA VAL B 70 7752 8183 6191 -144 -245 -237 C +ATOM 3520 C VAL B 70 46.553 21.786 56.376 1.00 57.43 C +ANISOU 3520 C VAL B 70 7516 8236 6069 -88 -265 -181 C +ATOM 3521 O VAL B 70 46.549 21.795 55.164 1.00 56.85 O +ANISOU 3521 O VAL B 70 7408 8166 6025 -87 -169 -84 O +ATOM 3522 CB VAL B 70 44.441 22.365 57.547 1.00 56.26 C +ANISOU 3522 CB VAL B 70 7640 7891 5842 -16 -238 -207 C +ATOM 3523 CG1 VAL B 70 43.712 23.383 58.408 1.00 56.72 C +ANISOU 3523 CG1 VAL B 70 7833 7785 5932 -59 -191 -278 C +ATOM 3524 CG2 VAL B 70 43.637 21.991 56.306 1.00 55.54 C +ANISOU 3524 CG2 VAL B 70 7558 7799 5745 68 -158 -55 C +ATOM 3525 N TYR B 71 47.160 20.846 57.099 1.00 58.10 N +ANISOU 3525 N TYR B 71 7531 8443 6100 -44 -384 -238 N +ATOM 3526 CA TYR B 71 47.948 19.764 56.504 1.00 58.51 C +ANISOU 3526 CA TYR B 71 7441 8625 6164 19 -393 -199 C +ATOM 3527 C TYR B 71 47.170 18.455 56.387 1.00 55.74 C +ANISOU 3527 C TYR B 71 7156 8316 5705 174 -393 -148 C +ATOM 3528 O TYR B 71 47.612 17.517 55.729 1.00 54.88 O +ANISOU 3528 O TYR B 71 6961 8284 5607 238 -357 -112 O +ATOM 3529 CB TYR B 71 49.203 19.525 57.333 1.00 61.35 C +ANISOU 3529 CB TYR B 71 7648 9089 6571 -22 -528 -270 C +ATOM 3530 CG TYR B 71 50.160 20.700 57.376 1.00 65.34 C +ANISOU 3530 CG TYR B 71 8050 9573 7200 -196 -533 -328 C +ATOM 3531 CD1 TYR B 71 50.057 21.673 58.370 1.00 66.80 C +ANISOU 3531 CD1 TYR B 71 8320 9690 7371 -314 -603 -425 C +ATOM 3532 CD2 TYR B 71 51.161 20.850 56.417 1.00 67.81 C +ANISOU 3532 CD2 TYR B 71 8190 9926 7647 -255 -450 -295 C +ATOM 3533 CE1 TYR B 71 50.926 22.752 58.417 1.00 69.31 C +ANISOU 3533 CE1 TYR B 71 8550 9977 7807 -493 -605 -490 C +ATOM 3534 CE2 TYR B 71 52.038 21.929 56.457 1.00 70.17 C +ANISOU 3534 CE2 TYR B 71 8386 10200 8073 -428 -448 -348 C +ATOM 3535 CZ TYR B 71 51.917 22.877 57.458 1.00 70.97 C +ANISOU 3535 CZ TYR B 71 8573 10230 8161 -550 -532 -446 C +ATOM 3536 OH TYR B 71 52.787 23.944 57.506 1.00 73.34 O +ANISOU 3536 OH TYR B 71 8776 10496 8592 -741 -528 -509 O +ATOM 3537 N ALA B 72 46.025 18.392 57.057 1.00 53.06 N +ANISOU 3537 N ALA B 72 6969 7917 5271 228 -420 -153 N +ATOM 3538 CA ALA B 72 45.086 17.301 56.897 1.00 49.86 C +ANISOU 3538 CA ALA B 72 6645 7527 4772 354 -403 -100 C +ATOM 3539 C ALA B 72 43.780 17.784 57.478 1.00 47.84 C +ANISOU 3539 C ALA B 72 6546 7168 4462 367 -390 -101 C +ATOM 3540 O ALA B 72 43.746 18.793 58.155 1.00 47.75 O +ANISOU 3540 O ALA B 72 6580 7082 4477 293 -400 -160 O +ATOM 3541 CB ALA B 72 45.573 16.060 57.612 1.00 49.49 C +ANISOU 3541 CB ALA B 72 6551 7572 4680 444 -501 -122 C +ATOM 3542 N ILE B 73 42.705 17.070 57.190 1.00 45.45 N +ANISOU 3542 N ILE B 73 6320 6854 4094 456 -353 -41 N +ATOM 3543 CA ILE B 73 41.399 17.405 57.712 1.00 43.72 C +ANISOU 3543 CA ILE B 73 6226 6540 3844 485 -326 -30 C +ATOM 3544 C ILE B 73 40.781 16.169 58.320 1.00 42.36 C +ANISOU 3544 C ILE B 73 6118 6406 3571 587 -362 -30 C +ATOM 3545 O ILE B 73 40.710 15.135 57.685 1.00 42.30 O +ANISOU 3545 O ILE B 73 6084 6456 3531 644 -354 16 O +ATOM 3546 CB ILE B 73 40.478 17.924 56.601 1.00 43.33 C +ANISOU 3546 CB ILE B 73 6196 6424 3841 479 -235 76 C +ATOM 3547 CG1 ILE B 73 41.000 19.255 56.072 1.00 44.41 C +ANISOU 3547 CG1 ILE B 73 6291 6496 4087 377 -186 93 C +ATOM 3548 CG2 ILE B 73 39.058 18.083 57.106 1.00 42.73 C +ANISOU 3548 CG2 ILE B 73 6218 6256 3761 532 -200 104 C +ATOM 3549 CD1 ILE B 73 40.130 19.857 54.989 1.00 44.36 C +ANISOU 3549 CD1 ILE B 73 6300 6423 4130 369 -111 230 C +ATOM 3550 N PHE B 74 40.330 16.286 59.559 1.00 42.37 N +ANISOU 3550 N PHE B 74 6214 6366 3519 599 -389 -87 N +ATOM 3551 CA PHE B 74 39.565 15.237 60.218 1.00 41.10 C +ANISOU 3551 CA PHE B 74 6134 6217 3262 687 -402 -76 C +ATOM 3552 C PHE B 74 38.103 15.568 60.045 1.00 40.06 C +ANISOU 3552 C PHE B 74 6075 5988 3157 713 -304 -28 C +ATOM 3553 O PHE B 74 37.719 16.721 60.169 1.00 40.98 O +ANISOU 3553 O PHE B 74 6220 6006 3342 668 -244 -44 O +ATOM 3554 CB PHE B 74 39.910 15.159 61.698 1.00 42.02 C +ANISOU 3554 CB PHE B 74 6324 6356 3286 675 -481 -158 C +ATOM 3555 CG PHE B 74 39.063 14.178 62.447 1.00 41.70 C +ANISOU 3555 CG PHE B 74 6387 6314 3141 756 -476 -139 C +ATOM 3556 CD1 PHE B 74 39.355 12.819 62.416 1.00 41.12 C +ANISOU 3556 CD1 PHE B 74 6286 6315 3020 836 -531 -89 C +ATOM 3557 CD2 PHE B 74 37.953 14.611 63.152 1.00 41.49 C +ANISOU 3557 CD2 PHE B 74 6484 6196 3081 754 -394 -167 C +ATOM 3558 CE1 PHE B 74 38.557 11.916 63.085 1.00 40.94 C +ANISOU 3558 CE1 PHE B 74 6364 6278 2910 904 -515 -62 C +ATOM 3559 CE2 PHE B 74 37.154 13.722 63.811 1.00 41.28 C +ANISOU 3559 CE2 PHE B 74 6551 6166 2965 819 -370 -145 C +ATOM 3560 CZ PHE B 74 37.453 12.367 63.783 1.00 41.16 C +ANISOU 3560 CZ PHE B 74 6515 6228 2894 890 -436 -89 C +ATOM 3561 N GLY B 75 37.269 14.587 59.737 1.00 38.67 N +ANISOU 3561 N GLY B 75 5918 5828 2947 782 -282 33 N +ATOM 3562 CA GLY B 75 35.854 14.888 59.625 1.00 38.36 C +ANISOU 3562 CA GLY B 75 5919 5704 2951 805 -200 89 C +ATOM 3563 C GLY B 75 34.917 13.749 59.312 1.00 37.79 C +ANISOU 3563 C GLY B 75 5858 5656 2842 862 -184 153 C +ATOM 3564 O GLY B 75 35.317 12.600 59.211 1.00 36.63 O +ANISOU 3564 O GLY B 75 5709 5580 2627 892 -226 148 O +ATOM 3565 N PHE B 76 33.653 14.112 59.130 1.00 38.45 N +ANISOU 3565 N PHE B 76 5943 5671 2994 875 -118 218 N +ATOM 3566 CA PHE B 76 32.574 13.170 58.900 1.00 38.39 C +ANISOU 3566 CA PHE B 76 5937 5675 2971 911 -99 280 C +ATOM 3567 C PHE B 76 31.886 13.463 57.595 1.00 38.77 C +ANISOU 3567 C PHE B 76 5903 5734 3092 880 -101 396 C +ATOM 3568 O PHE B 76 31.798 14.605 57.195 1.00 39.32 O +ANISOU 3568 O PHE B 76 5928 5754 3256 857 -82 448 O +ATOM 3569 CB PHE B 76 31.554 13.293 60.019 1.00 38.88 C +ANISOU 3569 CB PHE B 76 6063 5651 3056 951 -18 263 C +ATOM 3570 CG PHE B 76 32.110 12.906 61.348 1.00 39.14 C +ANISOU 3570 CG PHE B 76 6203 5689 2979 968 -24 162 C +ATOM 3571 CD1 PHE B 76 32.902 13.805 62.070 1.00 39.87 C +ANISOU 3571 CD1 PHE B 76 6341 5754 3050 933 -31 73 C +ATOM 3572 CD2 PHE B 76 31.899 11.636 61.850 1.00 38.97 C +ANISOU 3572 CD2 PHE B 76 6239 5702 2865 1006 -32 161 C +ATOM 3573 CE1 PHE B 76 33.459 13.439 63.274 1.00 40.60 C +ANISOU 3573 CE1 PHE B 76 6536 5876 3014 931 -66 -8 C +ATOM 3574 CE2 PHE B 76 32.440 11.265 63.070 1.00 39.79 C +ANISOU 3574 CE2 PHE B 76 6446 5822 2850 1019 -55 94 C +ATOM 3575 CZ PHE B 76 33.231 12.160 63.777 1.00 40.60 C +ANISOU 3575 CZ PHE B 76 6593 5919 2913 979 -83 12 C +ATOM 3576 N TYR B 77 31.404 12.420 56.938 1.00 39.15 N +ANISOU 3576 N TYR B 77 5935 5845 3093 872 -126 441 N +ATOM 3577 CA TYR B 77 30.498 12.582 55.823 1.00 40.05 C +ANISOU 3577 CA TYR B 77 5978 5984 3255 830 -146 562 C +ATOM 3578 C TYR B 77 29.310 11.644 55.992 1.00 41.26 C +ANISOU 3578 C TYR B 77 6129 6141 3407 842 -134 593 C +ATOM 3579 O TYR B 77 29.325 10.718 56.789 1.00 40.31 O +ANISOU 3579 O TYR B 77 6074 6010 3230 876 -107 520 O +ATOM 3580 CB TYR B 77 31.196 12.392 54.475 1.00 39.58 C +ANISOU 3580 CB TYR B 77 5895 6022 3122 756 -201 589 C +ATOM 3581 CG TYR B 77 31.961 11.110 54.317 1.00 38.89 C +ANISOU 3581 CG TYR B 77 5855 6001 2919 746 -209 498 C +ATOM 3582 CD1 TYR B 77 31.322 9.887 54.362 1.00 38.65 C +ANISOU 3582 CD1 TYR B 77 5858 5987 2839 747 -205 482 C +ATOM 3583 CD2 TYR B 77 33.323 11.118 54.066 1.00 39.34 C +ANISOU 3583 CD2 TYR B 77 5916 6095 2937 734 -208 433 C +ATOM 3584 CE1 TYR B 77 32.012 8.703 54.198 1.00 38.73 C +ANISOU 3584 CE1 TYR B 77 5916 6030 2768 745 -191 401 C +ATOM 3585 CE2 TYR B 77 34.040 9.938 53.898 1.00 39.20 C +ANISOU 3585 CE2 TYR B 77 5927 6120 2846 741 -194 356 C +ATOM 3586 CZ TYR B 77 33.381 8.730 53.984 1.00 39.19 C +ANISOU 3586 CZ TYR B 77 5971 6116 2802 751 -182 339 C +ATOM 3587 OH TYR B 77 34.067 7.541 53.828 1.00 39.35 O +ANISOU 3587 OH TYR B 77 6025 6150 2774 766 -149 265 O +ATOM 3588 N ASP B 78 28.261 11.933 55.250 1.00 44.54 N +ANISOU 3588 N ASP B 78 6460 6567 3894 809 -159 716 N +ATOM 3589 CA ASP B 78 27.091 11.078 55.192 1.00 47.01 C +ANISOU 3589 CA ASP B 78 6740 6899 4219 792 -164 761 C +ATOM 3590 C ASP B 78 26.822 10.814 53.716 1.00 48.12 C +ANISOU 3590 C ASP B 78 6826 7150 4305 688 -263 851 C +ATOM 3591 O ASP B 78 27.566 11.279 52.850 1.00 47.31 O +ANISOU 3591 O ASP B 78 6727 7101 4147 641 -309 874 O +ATOM 3592 CB ASP B 78 25.890 11.706 55.918 1.00 48.65 C +ANISOU 3592 CB ASP B 78 6879 7011 4593 852 -93 830 C +ATOM 3593 CG ASP B 78 25.385 12.998 55.261 1.00 52.05 C +ANISOU 3593 CG ASP B 78 7191 7412 5171 854 -117 979 C +ATOM 3594 OD1 ASP B 78 25.969 13.516 54.290 1.00 54.19 O +ANISOU 3594 OD1 ASP B 78 7445 7736 5407 806 -190 1036 O +ATOM 3595 OD2 ASP B 78 24.363 13.530 55.725 1.00 56.74 O +ANISOU 3595 OD2 ASP B 78 7704 7920 5935 909 -49 1052 O +ATOM 3596 N GLN B 79 25.775 10.052 53.432 1.00 51.12 N +ANISOU 3596 N GLN B 79 7163 7570 4689 638 -295 898 N +ATOM 3597 CA GLN B 79 25.456 9.646 52.066 1.00 53.56 C +ANISOU 3597 CA GLN B 79 7440 8001 4910 509 -402 968 C +ATOM 3598 C GLN B 79 25.302 10.888 51.172 1.00 53.68 C +ANISOU 3598 C GLN B 79 7365 8054 4977 480 -481 1130 C +ATOM 3599 O GLN B 79 25.688 10.858 50.015 1.00 54.14 O +ANISOU 3599 O GLN B 79 7445 8216 4907 377 -559 1165 O +ATOM 3600 CB GLN B 79 24.192 8.781 52.075 1.00 56.94 C +ANISOU 3600 CB GLN B 79 7812 8452 5370 454 -427 1003 C +ATOM 3601 CG GLN B 79 23.926 7.986 50.805 1.00 61.95 C +ANISOU 3601 CG GLN B 79 8455 9217 5867 290 -533 1018 C +ATOM 3602 CD GLN B 79 24.717 6.671 50.692 1.00 63.20 C +ANISOU 3602 CD GLN B 79 8761 9385 5864 236 -482 843 C +ATOM 3603 OE1 GLN B 79 25.725 6.469 51.371 1.00 63.60 O +ANISOU 3603 OE1 GLN B 79 8901 9366 5894 327 -391 729 O +ATOM 3604 NE2 GLN B 79 24.249 5.770 49.814 1.00 65.09 N +ANISOU 3604 NE2 GLN B 79 9022 9709 5997 81 -543 823 N +ATOM 3605 N MET B 80 24.777 11.982 51.715 1.00 53.47 N +ANISOU 3605 N MET B 80 7246 7932 5134 571 -447 1229 N +ATOM 3606 CA MET B 80 24.632 13.228 50.949 1.00 54.91 C +ANISOU 3606 CA MET B 80 7341 8121 5401 563 -509 1404 C +ATOM 3607 C MET B 80 25.916 14.001 50.655 1.00 51.15 C +ANISOU 3607 C MET B 80 6938 7628 4868 564 -487 1372 C +ATOM 3608 O MET B 80 25.999 14.636 49.620 1.00 51.20 O +ANISOU 3608 O MET B 80 6910 7692 4850 503 -564 1509 O +ATOM 3609 CB MET B 80 23.648 14.178 51.636 1.00 59.38 C +ANISOU 3609 CB MET B 80 7780 8558 6222 672 -451 1521 C +ATOM 3610 CG MET B 80 22.197 13.923 51.271 1.00 64.59 C +ANISOU 3610 CG MET B 80 8282 9269 6989 643 -532 1680 C +ATOM 3611 SD MET B 80 21.119 15.241 51.896 1.00 74.14 S +ANISOU 3611 SD MET B 80 9311 10310 8546 787 -444 1849 S +ATOM 3612 CE MET B 80 21.705 16.665 50.954 1.00 73.10 C +ANISOU 3612 CE MET B 80 9156 10158 8458 790 -508 2019 C +ATOM 3613 N SER B 81 26.886 13.978 51.566 1.00 47.37 N +ANISOU 3613 N SER B 81 6550 7075 4371 626 -388 1207 N +ATOM 3614 CA SER B 81 28.080 14.818 51.464 1.00 46.23 C +ANISOU 3614 CA SER B 81 6452 6897 4215 629 -355 1172 C +ATOM 3615 C SER B 81 29.337 14.076 51.011 1.00 45.64 C +ANISOU 3615 C SER B 81 6469 6914 3956 564 -360 1046 C +ATOM 3616 O SER B 81 30.347 14.698 50.732 1.00 44.36 O +ANISOU 3616 O SER B 81 6328 6747 3777 545 -339 1027 O +ATOM 3617 CB SER B 81 28.349 15.521 52.795 1.00 45.98 C +ANISOU 3617 CB SER B 81 6444 6716 4309 729 -247 1082 C +ATOM 3618 OG SER B 81 28.754 14.622 53.830 1.00 45.33 O +ANISOU 3618 OG SER B 81 6444 6626 4152 766 -199 911 O +ATOM 3619 N MET B 82 29.261 12.753 50.919 1.00 46.63 N +ANISOU 3619 N MET B 82 6641 7113 3963 530 -375 962 N +ATOM 3620 CA MET B 82 30.409 11.908 50.597 1.00 47.06 C +ANISOU 3620 CA MET B 82 6776 7229 3874 489 -350 830 C +ATOM 3621 C MET B 82 31.067 12.323 49.285 1.00 46.35 C +ANISOU 3621 C MET B 82 6695 7224 3689 387 -372 883 C +ATOM 3622 O MET B 82 32.267 12.545 49.253 1.00 45.73 O +ANISOU 3622 O MET B 82 6642 7142 3591 390 -320 810 O +ATOM 3623 CB MET B 82 29.954 10.449 50.495 1.00 49.02 C +ANISOU 3623 CB MET B 82 7069 7525 4028 451 -357 761 C +ATOM 3624 CG MET B 82 31.055 9.440 50.233 1.00 51.04 C +ANISOU 3624 CG MET B 82 7407 7817 4168 427 -304 619 C +ATOM 3625 SD MET B 82 30.424 7.956 49.396 1.00 56.91 S +ANISOU 3625 SD MET B 82 8214 8633 4777 310 -316 572 S +ATOM 3626 CE MET B 82 30.289 8.574 47.730 1.00 58.28 C +ANISOU 3626 CE MET B 82 8383 8936 4824 148 -389 682 C +ATOM 3627 N ASN B 83 30.279 12.436 48.219 1.00 46.61 N +ANISOU 3627 N ASN B 83 6705 7340 3662 291 -453 1018 N +ATOM 3628 CA ASN B 83 30.803 12.756 46.897 1.00 47.02 C +ANISOU 3628 CA ASN B 83 6789 7490 3583 172 -475 1082 C +ATOM 3629 C ASN B 83 31.460 14.127 46.834 1.00 45.91 C +ANISOU 3629 C ASN B 83 6617 7293 3532 197 -446 1162 C +ATOM 3630 O ASN B 83 32.505 14.264 46.222 1.00 46.25 O +ANISOU 3630 O ASN B 83 6704 7376 3490 138 -395 1123 O +ATOM 3631 CB ASN B 83 29.718 12.627 45.801 1.00 49.65 C +ANISOU 3631 CB ASN B 83 7107 7940 3816 48 -597 1234 C +ATOM 3632 CG ASN B 83 29.328 11.169 45.500 1.00 50.82 C +ANISOU 3632 CG ASN B 83 7320 8168 3819 -39 -614 1124 C +ATOM 3633 OD1 ASN B 83 28.155 10.875 45.217 1.00 53.48 O +ANISOU 3633 OD1 ASN B 83 7613 8563 4142 -102 -720 1215 O +ATOM 3634 ND2 ASN B 83 30.301 10.259 45.533 1.00 50.06 N +ANISOU 3634 ND2 ASN B 83 7320 8070 3630 -49 -509 934 N +ATOM 3635 N THR B 84 30.869 15.145 47.452 1.00 45.21 N +ANISOU 3635 N THR B 84 6452 7098 3624 281 -461 1269 N +ATOM 3636 CA THR B 84 31.513 16.474 47.539 1.00 44.93 C +ANISOU 3636 CA THR B 84 6394 6972 3703 307 -413 1326 C +ATOM 3637 C THR B 84 32.883 16.400 48.250 1.00 43.79 C +ANISOU 3637 C THR B 84 6289 6781 3566 341 -316 1136 C +ATOM 3638 O THR B 84 33.884 16.880 47.717 1.00 43.86 O +ANISOU 3638 O THR B 84 6312 6806 3545 284 -274 1132 O +ATOM 3639 CB THR B 84 30.607 17.512 48.255 1.00 45.02 C +ANISOU 3639 CB THR B 84 6324 6841 3938 405 -412 1442 C +ATOM 3640 OG1 THR B 84 29.404 17.679 47.523 1.00 46.06 O +ANISOU 3640 OG1 THR B 84 6387 7021 4091 378 -513 1651 O +ATOM 3641 CG2 THR B 84 31.274 18.870 48.365 1.00 45.31 C +ANISOU 3641 CG2 THR B 84 6352 6760 4104 422 -346 1486 C +ATOM 3642 N LEU B 85 32.933 15.799 49.440 1.00 42.45 N +ANISOU 3642 N LEU B 85 6130 6560 3437 426 -286 992 N +ATOM 3643 CA LEU B 85 34.172 15.779 50.207 1.00 42.18 C +ANISOU 3643 CA LEU B 85 6114 6490 3422 459 -226 836 C +ATOM 3644 C LEU B 85 35.264 14.960 49.524 1.00 42.71 C +ANISOU 3644 C LEU B 85 6208 6658 3359 400 -197 747 C +ATOM 3645 O LEU B 85 36.403 15.403 49.483 1.00 44.45 O +ANISOU 3645 O LEU B 85 6409 6873 3605 378 -151 697 O +ATOM 3646 CB LEU B 85 33.940 15.289 51.643 1.00 41.27 C +ANISOU 3646 CB LEU B 85 6015 6309 3354 556 -215 722 C +ATOM 3647 CG LEU B 85 33.246 16.327 52.520 1.00 41.62 C +ANISOU 3647 CG LEU B 85 6042 6222 3548 615 -191 762 C +ATOM 3648 CD1 LEU B 85 32.638 15.733 53.771 1.00 41.32 C +ANISOU 3648 CD1 LEU B 85 6036 6136 3525 694 -173 681 C +ATOM 3649 CD2 LEU B 85 34.206 17.436 52.892 1.00 42.25 C +ANISOU 3649 CD2 LEU B 85 6118 6223 3709 599 -149 715 C +ATOM 3650 N THR B 86 34.938 13.794 48.976 1.00 41.80 N +ANISOU 3650 N THR B 86 6132 6628 3120 368 -209 721 N +ATOM 3651 CA THR B 86 35.961 12.930 48.383 1.00 41.04 C +ANISOU 3651 CA THR B 86 6068 6605 2920 323 -146 616 C +ATOM 3652 C THR B 86 36.468 13.527 47.089 1.00 41.69 C +ANISOU 3652 C THR B 86 6159 6752 2926 208 -112 688 C +ATOM 3653 O THR B 86 37.632 13.375 46.750 1.00 42.35 O +ANISOU 3653 O THR B 86 6238 6863 2988 179 -26 609 O +ATOM 3654 CB THR B 86 35.472 11.465 48.171 1.00 40.77 C +ANISOU 3654 CB THR B 86 6093 6618 2778 310 -144 548 C +ATOM 3655 OG1 THR B 86 34.351 11.411 47.266 1.00 41.31 O +ANISOU 3655 OG1 THR B 86 6192 6752 2750 215 -208 655 O +ATOM 3656 CG2 THR B 86 35.103 10.852 49.489 1.00 39.37 C +ANISOU 3656 CG2 THR B 86 5913 6369 2675 424 -161 482 C +ATOM 3657 N SER B 87 35.600 14.242 46.394 1.00 42.00 N +ANISOU 3657 N SER B 87 6204 6815 2938 144 -175 851 N +ATOM 3658 CA SER B 87 35.959 14.938 45.160 1.00 42.99 C +ANISOU 3658 CA SER B 87 6351 7002 2978 27 -154 959 C +ATOM 3659 C SER B 87 36.897 16.133 45.362 1.00 43.46 C +ANISOU 3659 C SER B 87 6360 6987 3162 36 -94 982 C +ATOM 3660 O SER B 87 37.862 16.287 44.633 1.00 44.20 O +ANISOU 3660 O SER B 87 6469 7126 3196 -42 -10 964 O +ATOM 3661 CB SER B 87 34.699 15.422 44.476 1.00 43.62 C +ANISOU 3661 CB SER B 87 6436 7123 3015 -30 -265 1162 C +ATOM 3662 OG SER B 87 35.042 16.274 43.418 1.00 45.58 O +ANISOU 3662 OG SER B 87 6706 7416 3197 -133 -253 1298 O +ATOM 3663 N PHE B 88 36.585 16.992 46.326 1.00 43.28 N +ANISOU 3663 N PHE B 88 6283 6844 3314 121 -125 1018 N +ATOM 3664 CA PHE B 88 37.470 18.093 46.695 1.00 44.04 C +ANISOU 3664 CA PHE B 88 6337 6850 3545 123 -67 1009 C +ATOM 3665 C PHE B 88 38.787 17.623 47.305 1.00 44.25 C +ANISOU 3665 C PHE B 88 6330 6881 3599 144 -1 822 C +ATOM 3666 O PHE B 88 39.816 18.234 47.075 1.00 45.39 O +ANISOU 3666 O PHE B 88 6439 7015 3792 90 65 806 O +ATOM 3667 CB PHE B 88 36.770 19.070 47.666 1.00 43.62 C +ANISOU 3667 CB PHE B 88 6249 6648 3673 203 -98 1064 C +ATOM 3668 CG PHE B 88 35.979 20.127 46.958 1.00 44.56 C +ANISOU 3668 CG PHE B 88 6362 6718 3848 172 -125 1286 C +ATOM 3669 CD1 PHE B 88 34.760 19.815 46.382 1.00 44.91 C +ANISOU 3669 CD1 PHE B 88 6410 6823 3830 171 -212 1431 C +ATOM 3670 CD2 PHE B 88 36.471 21.412 46.815 1.00 45.23 C +ANISOU 3670 CD2 PHE B 88 6431 6700 4054 137 -69 1362 C +ATOM 3671 CE1 PHE B 88 34.021 20.773 45.712 1.00 46.19 C +ANISOU 3671 CE1 PHE B 88 6547 6946 4055 151 -257 1667 C +ATOM 3672 CE2 PHE B 88 35.744 22.376 46.151 1.00 46.84 C +ANISOU 3672 CE2 PHE B 88 6625 6844 4326 120 -94 1592 C +ATOM 3673 CZ PHE B 88 34.511 22.060 45.596 1.00 47.23 C +ANISOU 3673 CZ PHE B 88 6667 6960 4317 134 -194 1756 C +ATOM 3674 N CYS B 89 38.763 16.564 48.101 1.00 43.70 N +ANISOU 3674 N CYS B 89 6262 6828 3514 224 -22 694 N +ATOM 3675 CA CYS B 89 40.005 16.007 48.655 1.00 44.03 C +ANISOU 3675 CA CYS B 89 6254 6886 3587 255 21 542 C +ATOM 3676 C CYS B 89 40.957 15.506 47.619 1.00 44.17 C +ANISOU 3676 C CYS B 89 6262 6991 3529 185 117 505 C +ATOM 3677 O CYS B 89 42.156 15.764 47.721 1.00 44.68 O +ANISOU 3677 O CYS B 89 6248 7055 3671 168 176 443 O +ATOM 3678 CB CYS B 89 39.724 14.878 49.641 1.00 43.82 C +ANISOU 3678 CB CYS B 89 6241 6858 3550 358 -22 443 C +ATOM 3679 SG CYS B 89 39.190 15.699 51.128 1.00 46.58 S +ANISOU 3679 SG CYS B 89 6586 7094 4016 428 -90 436 S +ATOM 3680 N GLY B 90 40.409 14.795 46.631 1.00 43.99 N +ANISOU 3680 N GLY B 90 6315 7042 3356 134 137 538 N +ATOM 3681 CA GLY B 90 41.191 14.244 45.540 1.00 44.35 C +ANISOU 3681 CA GLY B 90 6382 7168 3300 53 258 491 C +ATOM 3682 C GLY B 90 41.707 15.301 44.608 1.00 45.02 C +ANISOU 3682 C GLY B 90 6463 7273 3367 -61 325 584 C +ATOM 3683 O GLY B 90 42.783 15.155 44.075 1.00 46.68 O +ANISOU 3683 O GLY B 90 6643 7519 3572 -111 453 522 O +ATOM 3684 N ALA B 91 40.946 16.360 44.390 1.00 44.79 N +ANISOU 3684 N ALA B 91 6460 7215 3342 -101 252 743 N +ATOM 3685 CA ALA B 91 41.358 17.397 43.441 1.00 45.90 C +ANISOU 3685 CA ALA B 91 6613 7366 3459 -217 316 863 C +ATOM 3686 C ALA B 91 42.412 18.303 44.057 1.00 46.12 C +ANISOU 3686 C ALA B 91 6537 7308 3677 -206 370 824 C +ATOM 3687 O ALA B 91 43.339 18.714 43.383 1.00 47.63 O +ANISOU 3687 O ALA B 91 6707 7521 3868 -297 485 835 O +ATOM 3688 CB ALA B 91 40.170 18.206 42.975 1.00 46.26 C +ANISOU 3688 CB ALA B 91 6713 7399 3463 -255 215 1073 C +ATOM 3689 N LEU B 92 42.298 18.584 45.348 1.00 45.18 N +ANISOU 3689 N LEU B 92 6356 7095 3712 -109 294 770 N +ATOM 3690 CA LEU B 92 43.252 19.455 46.042 1.00 45.59 C +ANISOU 3690 CA LEU B 92 6315 7066 3941 -117 323 717 C +ATOM 3691 C LEU B 92 44.360 18.720 46.824 1.00 44.93 C +ANISOU 3691 C LEU B 92 6128 7013 3931 -66 342 540 C +ATOM 3692 O LEU B 92 45.163 19.346 47.507 1.00 45.08 O +ANISOU 3692 O LEU B 92 6055 6981 4092 -81 339 482 O +ATOM 3693 CB LEU B 92 42.476 20.401 46.955 1.00 45.42 C +ANISOU 3693 CB LEU B 92 6302 6913 4040 -69 238 767 C +ATOM 3694 CG LEU B 92 41.469 21.265 46.183 1.00 46.39 C +ANISOU 3694 CG LEU B 92 6494 6987 4143 -109 223 973 C +ATOM 3695 CD1 LEU B 92 40.479 21.907 47.117 1.00 46.51 C +ANISOU 3695 CD1 LEU B 92 6520 6868 4283 -27 153 1013 C +ATOM 3696 CD2 LEU B 92 42.165 22.340 45.390 1.00 48.13 C +ANISOU 3696 CD2 LEU B 92 6704 7170 4412 -224 315 1072 C +ATOM 3697 N HIS B 93 44.410 17.395 46.709 1.00 44.38 N +ANISOU 3697 N HIS B 93 6067 7022 3773 -10 358 461 N +ATOM 3698 CA HIS B 93 45.487 16.594 47.305 1.00 44.20 C +ANISOU 3698 CA HIS B 93 5931 7029 3830 49 384 323 C +ATOM 3699 C HIS B 93 45.567 16.785 48.828 1.00 43.24 C +ANISOU 3699 C HIS B 93 5749 6852 3826 128 257 261 C +ATOM 3700 O HIS B 93 46.643 16.741 49.432 1.00 43.64 O +ANISOU 3700 O HIS B 93 5673 6917 3990 141 247 183 O +ATOM 3701 CB HIS B 93 46.824 16.908 46.617 1.00 45.83 C +ANISOU 3701 CB HIS B 93 6034 7270 4107 -37 523 301 C +ATOM 3702 CG HIS B 93 46.913 16.414 45.209 1.00 46.79 C +ANISOU 3702 CG HIS B 93 6224 7462 4092 -109 674 323 C +ATOM 3703 ND1 HIS B 93 48.114 16.126 44.598 1.00 48.51 N +ANISOU 3703 ND1 HIS B 93 6349 7724 4356 -153 841 261 N +ATOM 3704 CD2 HIS B 93 45.952 16.154 44.290 1.00 46.94 C +ANISOU 3704 CD2 HIS B 93 6395 7519 3919 -157 689 395 C +ATOM 3705 CE1 HIS B 93 47.889 15.706 43.365 1.00 49.11 C +ANISOU 3705 CE1 HIS B 93 6541 7857 4260 -228 968 282 C +ATOM 3706 NE2 HIS B 93 46.586 15.708 43.155 1.00 48.23 N +ANISOU 3706 NE2 HIS B 93 6582 7751 3992 -239 865 363 N +ATOM 3707 N THR B 94 44.402 16.965 49.440 1.00 42.05 N +ANISOU 3707 N THR B 94 5689 6647 3641 176 160 297 N +ATOM 3708 CA THR B 94 44.296 17.197 50.857 1.00 41.35 C +ANISOU 3708 CA THR B 94 5586 6502 3622 234 54 238 C +ATOM 3709 C THR B 94 43.716 15.975 51.519 1.00 40.33 C +ANISOU 3709 C THR B 94 5503 6397 3424 348 -8 195 C +ATOM 3710 O THR B 94 42.606 15.564 51.206 1.00 39.45 O +ANISOU 3710 O THR B 94 5485 6280 3224 376 -11 247 O +ATOM 3711 CB THR B 94 43.427 18.410 51.081 1.00 41.34 C +ANISOU 3711 CB THR B 94 5654 6397 3656 199 29 309 C +ATOM 3712 OG1 THR B 94 44.147 19.538 50.569 1.00 42.71 O +ANISOU 3712 OG1 THR B 94 5776 6532 3916 90 93 342 O +ATOM 3713 CG2 THR B 94 43.109 18.627 52.546 1.00 40.84 C +ANISOU 3713 CG2 THR B 94 5615 6266 3634 251 -58 235 C +ATOM 3714 N SER B 95 44.483 15.386 52.431 1.00 40.76 N +ANISOU 3714 N SER B 95 5482 6479 3523 407 -63 112 N +ATOM 3715 CA SER B 95 44.087 14.135 53.043 1.00 39.84 C +ANISOU 3715 CA SER B 95 5405 6381 3349 517 -111 82 C +ATOM 3716 C SER B 95 42.959 14.358 54.021 1.00 39.08 C +ANISOU 3716 C SER B 95 5414 6224 3209 556 -189 91 C +ATOM 3717 O SER B 95 43.029 15.255 54.874 1.00 39.26 O +ANISOU 3717 O SER B 95 5439 6202 3273 525 -244 64 O +ATOM 3718 CB SER B 95 45.279 13.465 53.710 1.00 40.55 C +ANISOU 3718 CB SER B 95 5373 6519 3512 575 -154 21 C +ATOM 3719 OG SER B 95 46.210 13.027 52.729 1.00 41.72 O +ANISOU 3719 OG SER B 95 5421 6714 3713 562 -45 11 O +ATOM 3720 N PHE B 96 41.906 13.565 53.852 1.00 38.81 N +ANISOU 3720 N PHE B 96 5468 6182 3093 609 -178 122 N +ATOM 3721 CA PHE B 96 40.724 13.602 54.714 1.00 39.02 C +ANISOU 3721 CA PHE B 96 5591 6152 3083 653 -225 136 C +ATOM 3722 C PHE B 96 40.742 12.357 55.627 1.00 38.46 C +ANISOU 3722 C PHE B 96 5544 6098 2969 749 -272 94 C +ATOM 3723 O PHE B 96 40.651 11.238 55.140 1.00 38.18 O +ANISOU 3723 O PHE B 96 5519 6088 2899 790 -236 99 O +ATOM 3724 CB PHE B 96 39.466 13.626 53.815 1.00 38.90 C +ANISOU 3724 CB PHE B 96 5638 6118 3021 631 -184 221 C +ATOM 3725 CG PHE B 96 38.174 13.851 54.559 1.00 39.13 C +ANISOU 3725 CG PHE B 96 5738 6078 3049 669 -208 252 C +ATOM 3726 CD1 PHE B 96 37.899 15.073 55.139 1.00 40.00 C +ANISOU 3726 CD1 PHE B 96 5860 6106 3231 650 -207 260 C +ATOM 3727 CD2 PHE B 96 37.224 12.845 54.669 1.00 39.09 C +ANISOU 3727 CD2 PHE B 96 5787 6078 2985 718 -210 268 C +ATOM 3728 CE1 PHE B 96 36.715 15.282 55.834 1.00 39.98 C +ANISOU 3728 CE1 PHE B 96 5915 6028 3247 692 -197 281 C +ATOM 3729 CE2 PHE B 96 36.042 13.054 55.371 1.00 38.76 C +ANISOU 3729 CE2 PHE B 96 5794 5970 2961 752 -212 297 C +ATOM 3730 CZ PHE B 96 35.791 14.271 55.952 1.00 39.13 C +ANISOU 3730 CZ PHE B 96 5846 5936 3084 744 -199 303 C +ATOM 3731 N VAL B 97 40.883 12.528 56.930 1.00 39.00 N +ANISOU 3731 N VAL B 97 5632 6149 3034 778 -346 55 N +ATOM 3732 CA VAL B 97 40.867 11.369 57.849 1.00 39.40 C +ANISOU 3732 CA VAL B 97 5719 6216 3033 868 -397 41 C +ATOM 3733 C VAL B 97 39.505 11.289 58.517 1.00 39.28 C +ANISOU 3733 C VAL B 97 5829 6140 2953 895 -387 58 C +ATOM 3734 O VAL B 97 39.043 12.280 59.031 1.00 40.27 O +ANISOU 3734 O VAL B 97 6001 6218 3082 855 -386 43 O +ATOM 3735 CB VAL B 97 41.952 11.507 58.906 1.00 40.66 C +ANISOU 3735 CB VAL B 97 5824 6418 3205 873 -502 1 C +ATOM 3736 CG1 VAL B 97 42.137 10.196 59.669 1.00 40.96 C +ANISOU 3736 CG1 VAL B 97 5878 6482 3201 975 -560 21 C +ATOM 3737 CG2 VAL B 97 43.251 11.957 58.242 1.00 41.71 C +ANISOU 3737 CG2 VAL B 97 5809 6603 3437 820 -502 -15 C +ATOM 3738 N THR B 98 38.845 10.132 58.489 1.00 39.11 N +ANISOU 3738 N THR B 98 5861 6110 2888 957 -361 85 N +ATOM 3739 CA THR B 98 37.402 10.047 58.809 1.00 38.55 C +ANISOU 3739 CA THR B 98 5886 5980 2779 968 -322 113 C +ATOM 3740 C THR B 98 36.995 8.752 59.517 1.00 38.63 C +ANISOU 3740 C THR B 98 5968 5976 2731 1042 -323 124 C +ATOM 3741 O THR B 98 37.468 7.673 59.184 1.00 39.46 O +ANISOU 3741 O THR B 98 6052 6100 2839 1086 -319 130 O +ATOM 3742 CB THR B 98 36.546 10.156 57.511 1.00 38.04 C +ANISOU 3742 CB THR B 98 5806 5908 2738 923 -261 165 C +ATOM 3743 OG1 THR B 98 35.158 10.278 57.842 1.00 38.54 O +ANISOU 3743 OG1 THR B 98 5925 5916 2800 928 -230 204 O +ATOM 3744 CG2 THR B 98 36.704 8.952 56.629 1.00 37.74 C +ANISOU 3744 CG2 THR B 98 5759 5906 2675 931 -231 168 C +ATOM 3745 N PRO B 99 36.097 8.839 60.491 1.00 38.83 N +ANISOU 3745 N PRO B 99 6083 5955 2712 1057 -309 129 N +ATOM 3746 CA PRO B 99 35.551 7.611 61.062 1.00 38.58 C +ANISOU 3746 CA PRO B 99 6129 5899 2629 1116 -290 154 C +ATOM 3747 C PRO B 99 34.192 7.256 60.501 1.00 38.10 C +ANISOU 3747 C PRO B 99 6091 5794 2590 1098 -210 191 C +ATOM 3748 O PRO B 99 33.573 6.324 60.976 1.00 38.73 O +ANISOU 3748 O PRO B 99 6237 5839 2638 1131 -175 212 O +ATOM 3749 CB PRO B 99 35.455 7.947 62.549 1.00 39.11 C +ANISOU 3749 CB PRO B 99 6290 5952 2618 1127 -315 135 C +ATOM 3750 CG PRO B 99 35.215 9.396 62.597 1.00 39.35 C +ANISOU 3750 CG PRO B 99 6313 5957 2679 1064 -292 94 C +ATOM 3751 CD PRO B 99 35.813 10.004 61.351 1.00 39.25 C +ANISOU 3751 CD PRO B 99 6184 5973 2755 1023 -307 95 C +ATOM 3752 N SER B 100 33.739 7.982 59.489 1.00 37.87 N +ANISOU 3752 N SER B 100 6001 5770 2616 1040 -187 209 N +ATOM 3753 CA SER B 100 32.508 7.651 58.782 1.00 38.06 C +ANISOU 3753 CA SER B 100 6016 5776 2666 1006 -141 257 C +ATOM 3754 C SER B 100 32.602 6.355 58.013 1.00 38.85 C +ANISOU 3754 C SER B 100 6123 5898 2740 996 -130 252 C +ATOM 3755 O SER B 100 33.670 5.739 57.925 1.00 38.83 O +ANISOU 3755 O SER B 100 6121 5912 2719 1028 -142 215 O +ATOM 3756 CB SER B 100 32.162 8.745 57.787 1.00 37.61 C +ANISOU 3756 CB SER B 100 5884 5736 2670 944 -146 302 C +ATOM 3757 OG SER B 100 31.943 9.954 58.472 1.00 38.03 O +ANISOU 3757 OG SER B 100 5935 5738 2774 954 -129 305 O +ATOM 3758 N PHE B 101 31.473 5.949 57.438 1.00 39.48 N +ANISOU 3758 N PHE B 101 6200 5969 2829 945 -102 287 N +ATOM 3759 CA PHE B 101 31.393 4.676 56.785 1.00 41.02 C +ANISOU 3759 CA PHE B 101 6425 6166 2994 913 -76 265 C +ATOM 3760 C PHE B 101 32.392 4.605 55.648 1.00 42.57 C +ANISOU 3760 C PHE B 101 6592 6416 3164 873 -82 224 C +ATOM 3761 O PHE B 101 32.567 5.593 54.925 1.00 43.08 O +ANISOU 3761 O PHE B 101 6602 6535 3230 822 -113 248 O +ATOM 3762 CB PHE B 101 29.957 4.402 56.313 1.00 41.62 C +ANISOU 3762 CB PHE B 101 6488 6240 3085 834 -64 309 C +ATOM 3763 CG PHE B 101 29.481 5.277 55.176 1.00 41.31 C +ANISOU 3763 CG PHE B 101 6369 6269 3056 743 -114 366 C +ATOM 3764 CD1 PHE B 101 29.774 4.951 53.858 1.00 42.01 C +ANISOU 3764 CD1 PHE B 101 6457 6425 3078 648 -133 345 C +ATOM 3765 CD2 PHE B 101 28.726 6.414 55.425 1.00 41.27 C +ANISOU 3765 CD2 PHE B 101 6295 6256 3126 751 -133 446 C +ATOM 3766 CE1 PHE B 101 29.312 5.720 52.797 1.00 42.45 C +ANISOU 3766 CE1 PHE B 101 6451 6557 3119 553 -195 420 C +ATOM 3767 CE2 PHE B 101 28.273 7.213 54.384 1.00 41.78 C +ANISOU 3767 CE2 PHE B 101 6279 6380 3212 677 -190 531 C +ATOM 3768 CZ PHE B 101 28.578 6.869 53.064 1.00 42.62 C +ANISOU 3768 CZ PHE B 101 6392 6572 3229 574 -233 526 C +ATOM 3769 N PRO B 102 33.061 3.447 55.483 1.00 45.18 N +ANISOU 3769 N PRO B 102 6963 6721 3481 899 -36 167 N +ATOM 3770 CA PRO B 102 33.971 3.331 54.341 1.00 47.87 C +ANISOU 3770 CA PRO B 102 7280 7104 3801 854 -5 116 C +ATOM 3771 C PRO B 102 33.238 3.317 53.022 1.00 50.45 C +ANISOU 3771 C PRO B 102 7620 7484 4063 714 2 115 C +ATOM 3772 O PRO B 102 32.150 2.730 52.906 1.00 50.75 O +ANISOU 3772 O PRO B 102 7696 7504 4079 654 4 124 O +ATOM 3773 CB PRO B 102 34.692 2.009 54.576 1.00 47.93 C +ANISOU 3773 CB PRO B 102 7329 7043 3838 927 65 59 C +ATOM 3774 CG PRO B 102 33.749 1.230 55.421 1.00 47.43 C +ANISOU 3774 CG PRO B 102 7335 6905 3781 956 75 86 C +ATOM 3775 CD PRO B 102 33.035 2.222 56.285 1.00 45.71 C +ANISOU 3775 CD PRO B 102 7098 6708 3560 969 6 153 C +ATOM 3776 N THR B 103 33.852 3.968 52.041 1.00 55.12 N +ANISOU 3776 N THR B 103 8178 8146 4618 652 3 108 N +ATOM 3777 CA THR B 103 33.240 4.203 50.743 1.00 58.45 C +ANISOU 3777 CA THR B 103 8612 8645 4948 504 -14 131 C +ATOM 3778 C THR B 103 33.212 2.928 49.913 1.00 61.24 C +ANISOU 3778 C THR B 103 9053 8991 5222 416 67 34 C +ATOM 3779 O THR B 103 33.964 1.969 50.163 1.00 61.65 O +ANISOU 3779 O THR B 103 9143 8968 5311 483 164 -55 O +ATOM 3780 CB THR B 103 34.003 5.275 49.931 1.00 60.08 C +ANISOU 3780 CB THR B 103 8774 8927 5123 456 -21 159 C +ATOM 3781 OG1 THR B 103 35.177 4.711 49.341 1.00 60.85 O +ANISOU 3781 OG1 THR B 103 8897 9028 5195 448 84 60 O +ATOM 3782 CG2 THR B 103 34.417 6.450 50.796 1.00 60.44 C +ANISOU 3782 CG2 THR B 103 8744 8953 5266 548 -68 215 C +ATOM 3783 N ASP B 104 32.340 2.944 48.915 1.00 64.92 N +ANISOU 3783 N ASP B 104 9550 9533 5584 260 25 57 N +ATOM 3784 CA ASP B 104 32.201 1.839 47.970 1.00 68.11 C +ANISOU 3784 CA ASP B 104 10056 9944 5879 128 97 -48 C +ATOM 3785 C ASP B 104 33.359 1.935 46.971 1.00 68.01 C +ANISOU 3785 C ASP B 104 10080 9973 5785 77 194 -124 C +ATOM 3786 O ASP B 104 34.168 1.007 46.839 1.00 70.23 O +ANISOU 3786 O ASP B 104 10420 10181 6082 105 339 -251 O +ATOM 3787 CB ASP B 104 30.830 1.926 47.263 1.00 71.90 C +ANISOU 3787 CB ASP B 104 10545 10514 6259 -42 -12 16 C +ATOM 3788 CG ASP B 104 29.630 1.672 48.228 1.00 74.57 C +ANISOU 3788 CG ASP B 104 10835 10798 6697 0 -77 79 C +ATOM 3789 OD1 ASP B 104 29.565 0.573 48.837 1.00 77.04 O +ANISOU 3789 OD1 ASP B 104 11204 11005 7062 41 2 -1 O +ATOM 3790 OD2 ASP B 104 28.742 2.558 48.371 1.00 76.53 O +ANISOU 3790 OD2 ASP B 104 10990 11103 6985 -9 -194 216 O +ATOM 3791 N ALA B 105 33.442 3.093 46.316 1.00 64.73 N +ANISOU 3791 N ALA B 105 9625 9665 5303 12 127 -36 N +ATOM 3792 CA ALA B 105 34.488 3.391 45.351 1.00 63.32 C +ANISOU 3792 CA ALA B 105 9474 9540 5041 -48 220 -84 C +ATOM 3793 C ALA B 105 35.869 3.419 45.981 1.00 60.46 C +ANISOU 3793 C ALA B 105 9049 9102 4819 109 326 -139 C +ATOM 3794 O ALA B 105 36.009 3.747 47.143 1.00 59.40 O +ANISOU 3794 O ALA B 105 8830 8912 4826 255 271 -90 O +ATOM 3795 CB ALA B 105 34.212 4.732 44.668 1.00 63.33 C +ANISOU 3795 CB ALA B 105 9437 9661 4961 -138 112 59 C +ATOM 3796 N ASP B 106 36.875 3.075 45.187 1.00 59.61 N +ANISOU 3796 N ASP B 106 8981 8998 4668 67 480 -242 N +ATOM 3797 CA ASP B 106 38.275 3.199 45.557 1.00 58.08 C +ANISOU 3797 CA ASP B 106 8699 8755 4612 194 584 -282 C +ATOM 3798 C ASP B 106 38.747 4.623 45.258 1.00 55.88 C +ANISOU 3798 C ASP B 106 8343 8561 4326 164 536 -186 C +ATOM 3799 O ASP B 106 38.960 4.970 44.098 1.00 57.13 O +ANISOU 3799 O ASP B 106 8554 8800 4352 27 601 -191 O +ATOM 3800 CB ASP B 106 39.110 2.199 44.750 1.00 60.64 C +ANISOU 3800 CB ASP B 106 9091 9036 4910 155 803 -438 C +ATOM 3801 CG ASP B 106 38.711 0.731 45.006 1.00 61.65 C +ANISOU 3801 CG ASP B 106 9308 9048 5067 182 881 -545 C +ATOM 3802 OD1 ASP B 106 38.219 0.404 46.114 1.00 60.14 O +ANISOU 3802 OD1 ASP B 106 9084 8786 4979 295 788 -497 O +ATOM 3803 OD2 ASP B 106 38.908 -0.102 44.087 1.00 63.21 O +ANISOU 3803 OD2 ASP B 106 9619 9216 5180 81 1053 -683 O +ATOM 3804 N VAL B 107 38.896 5.448 46.295 1.00 52.67 N +ANISOU 3804 N VAL B 107 7824 8133 4052 279 430 -100 N +ATOM 3805 CA VAL B 107 39.310 6.834 46.107 1.00 50.98 C +ANISOU 3805 CA VAL B 107 7539 7975 3856 249 387 -9 C +ATOM 3806 C VAL B 107 40.677 7.096 46.710 1.00 49.91 C +ANISOU 3806 C VAL B 107 7279 7803 3881 356 443 -45 C +ATOM 3807 O VAL B 107 41.183 6.314 47.512 1.00 48.51 O +ANISOU 3807 O VAL B 107 7054 7560 3817 479 469 -107 O +ATOM 3808 CB VAL B 107 38.283 7.845 46.670 1.00 50.32 C +ANISOU 3808 CB VAL B 107 7429 7898 3790 257 219 125 C +ATOM 3809 CG1 VAL B 107 36.978 7.758 45.892 1.00 51.16 C +ANISOU 3809 CG1 VAL B 107 7622 8065 3748 133 150 192 C +ATOM 3810 CG2 VAL B 107 38.052 7.670 48.168 1.00 48.76 C +ANISOU 3810 CG2 VAL B 107 7183 7620 3722 402 145 123 C +ATOM 3811 N GLN B 108 41.268 8.201 46.278 1.00 49.95 N +ANISOU 3811 N GLN B 108 7228 7853 3898 299 457 6 N +ATOM 3812 CA GLN B 108 42.522 8.687 46.811 1.00 49.77 C +ANISOU 3812 CA GLN B 108 7066 7811 4032 369 486 -10 C +ATOM 3813 C GLN B 108 42.261 9.778 47.837 1.00 47.26 C +ANISOU 3813 C GLN B 108 6687 7469 3798 412 335 70 C +ATOM 3814 O GLN B 108 41.227 10.452 47.789 1.00 46.67 O +ANISOU 3814 O GLN B 108 6670 7399 3663 366 246 159 O +ATOM 3815 CB GLN B 108 43.404 9.257 45.682 1.00 52.28 C +ANISOU 3815 CB GLN B 108 7360 8183 4321 260 620 -13 C +ATOM 3816 CG GLN B 108 43.741 8.283 44.548 1.00 54.69 C +ANISOU 3816 CG GLN B 108 7744 8510 4524 192 811 -112 C +ATOM 3817 CD GLN B 108 44.241 6.932 45.052 1.00 56.75 C +ANISOU 3817 CD GLN B 108 7968 8697 4895 318 899 -229 C +ATOM 3818 OE1 GLN B 108 44.978 6.855 46.054 1.00 58.03 O +ANISOU 3818 OE1 GLN B 108 7988 8814 5246 453 863 -234 O +ATOM 3819 NE2 GLN B 108 43.824 5.849 44.375 1.00 58.49 N +ANISOU 3819 NE2 GLN B 108 8320 8901 5001 270 1008 -317 N +ATOM 3820 N PHE B 109 43.218 9.931 48.756 1.00 45.90 N +ANISOU 3820 N PHE B 109 6394 7271 3772 498 311 39 N +ATOM 3821 CA PHE B 109 43.251 10.998 49.781 1.00 44.31 C +ANISOU 3821 CA PHE B 109 6133 7045 3656 521 189 82 C +ATOM 3822 C PHE B 109 42.179 10.876 50.859 1.00 41.96 C +ANISOU 3822 C PHE B 109 5900 6701 3339 590 68 105 C +ATOM 3823 O PHE B 109 41.748 11.868 51.399 1.00 41.34 O +ANISOU 3823 O PHE B 109 5828 6593 3283 574 -5 149 O +ATOM 3824 CB PHE B 109 43.235 12.406 49.134 1.00 44.31 C +ANISOU 3824 CB PHE B 109 6129 7056 3649 407 198 156 C +ATOM 3825 CG PHE B 109 44.450 12.687 48.290 1.00 45.31 C +ANISOU 3825 CG PHE B 109 6174 7223 3819 336 321 135 C +ATOM 3826 CD1 PHE B 109 45.657 13.076 48.886 1.00 45.94 C +ANISOU 3826 CD1 PHE B 109 6105 7298 4049 356 318 94 C +ATOM 3827 CD2 PHE B 109 44.399 12.531 46.910 1.00 45.62 C +ANISOU 3827 CD2 PHE B 109 6280 7310 3741 239 443 153 C +ATOM 3828 CE1 PHE B 109 46.777 13.311 48.105 1.00 47.11 C +ANISOU 3828 CE1 PHE B 109 6160 7481 4257 289 449 75 C +ATOM 3829 CE2 PHE B 109 45.504 12.774 46.136 1.00 46.66 C +ANISOU 3829 CE2 PHE B 109 6344 7476 3909 170 584 130 C +ATOM 3830 CZ PHE B 109 46.690 13.158 46.725 1.00 47.53 C +ANISOU 3830 CZ PHE B 109 6291 7572 4194 199 595 92 C +ATOM 3831 N VAL B 110 41.771 9.658 51.185 1.00 40.86 N +ANISOU 3831 N VAL B 110 5811 6544 3167 664 68 71 N +ATOM 3832 CA VAL B 110 40.758 9.473 52.203 1.00 39.98 C +ANISOU 3832 CA VAL B 110 5765 6390 3035 724 -23 94 C +ATOM 3833 C VAL B 110 41.183 8.316 53.100 1.00 40.24 C +ANISOU 3833 C VAL B 110 5782 6396 3108 839 -37 48 C +ATOM 3834 O VAL B 110 41.328 7.192 52.637 1.00 40.47 O +ANISOU 3834 O VAL B 110 5831 6414 3129 868 42 12 O +ATOM 3835 CB VAL B 110 39.380 9.183 51.602 1.00 39.44 C +ANISOU 3835 CB VAL B 110 5799 6318 2866 675 -16 136 C +ATOM 3836 CG1 VAL B 110 38.348 9.031 52.699 1.00 38.70 C +ANISOU 3836 CG1 VAL B 110 5756 6173 2773 737 -90 160 C +ATOM 3837 CG2 VAL B 110 38.941 10.298 50.659 1.00 39.69 C +ANISOU 3837 CG2 VAL B 110 5839 6381 2859 567 -18 215 C +ATOM 3838 N ILE B 111 41.427 8.604 54.373 1.00 40.20 N +ANISOU 3838 N ILE B 111 5748 6378 3146 899 -134 52 N +ATOM 3839 CA ILE B 111 41.830 7.574 55.314 1.00 40.99 C +ANISOU 3839 CA ILE B 111 5835 6459 3278 1010 -172 42 C +ATOM 3840 C ILE B 111 40.621 7.175 56.133 1.00 40.73 C +ANISOU 3840 C ILE B 111 5922 6380 3172 1046 -214 67 C +ATOM 3841 O ILE B 111 40.106 7.979 56.912 1.00 39.71 O +ANISOU 3841 O ILE B 111 5832 6242 3012 1027 -280 82 O +ATOM 3842 CB ILE B 111 42.943 8.051 56.237 1.00 41.59 C +ANISOU 3842 CB ILE B 111 5803 6571 3425 1039 -270 39 C +ATOM 3843 CG1 ILE B 111 44.246 8.160 55.467 1.00 42.88 C +ANISOU 3843 CG1 ILE B 111 5820 6777 3695 1021 -210 16 C +ATOM 3844 CG2 ILE B 111 43.143 7.052 57.363 1.00 42.55 C +ANISOU 3844 CG2 ILE B 111 5933 6679 3554 1153 -344 63 C +ATOM 3845 CD1 ILE B 111 44.305 9.295 54.480 1.00 43.23 C +ANISOU 3845 CD1 ILE B 111 5843 6843 3737 900 -149 7 C +ATOM 3846 N GLN B 112 40.183 5.929 55.952 1.00 41.78 N +ANISOU 3846 N GLN B 112 6115 6472 3286 1093 -157 65 N +ATOM 3847 CA GLN B 112 38.925 5.466 56.514 1.00 42.43 C +ANISOU 3847 CA GLN B 112 6310 6505 3304 1109 -167 91 C +ATOM 3848 C GLN B 112 39.181 4.670 57.772 1.00 42.85 C +ANISOU 3848 C GLN B 112 6389 6525 3367 1215 -218 116 C +ATOM 3849 O GLN B 112 39.575 3.517 57.683 1.00 43.93 O +ANISOU 3849 O GLN B 112 6522 6622 3546 1284 -172 117 O +ATOM 3850 CB GLN B 112 38.180 4.639 55.470 1.00 43.43 C +ANISOU 3850 CB GLN B 112 6498 6606 3398 1062 -73 73 C +ATOM 3851 CG GLN B 112 37.721 5.474 54.288 1.00 44.22 C +ANISOU 3851 CG GLN B 112 6592 6754 3453 942 -50 77 C +ATOM 3852 CD GLN B 112 37.567 4.687 53.016 1.00 46.24 C +ANISOU 3852 CD GLN B 112 6888 7016 3663 871 43 35 C +ATOM 3853 OE1 GLN B 112 36.591 3.974 52.842 1.00 48.93 O +ANISOU 3853 OE1 GLN B 112 7304 7328 3955 837 62 32 O +ATOM 3854 NE2 GLN B 112 38.530 4.817 52.107 1.00 48.20 N +ANISOU 3854 NE2 GLN B 112 7089 7302 3920 834 111 -5 N +ATOM 3855 N MET B 113 38.976 5.292 58.933 1.00 42.89 N +ANISOU 3855 N MET B 113 6426 6540 3328 1224 -306 138 N +ATOM 3856 CA MET B 113 39.232 4.642 60.224 1.00 43.93 C +ANISOU 3856 CA MET B 113 6597 6659 3433 1309 -375 179 C +ATOM 3857 C MET B 113 38.314 3.460 60.532 1.00 42.85 C +ANISOU 3857 C MET B 113 6571 6446 3264 1357 -317 215 C +ATOM 3858 O MET B 113 38.714 2.567 61.237 1.00 44.46 O +ANISOU 3858 O MET B 113 6793 6624 3473 1443 -347 265 O +ATOM 3859 CB MET B 113 39.118 5.648 61.375 1.00 45.40 C +ANISOU 3859 CB MET B 113 6827 6878 3544 1277 -466 177 C +ATOM 3860 CG MET B 113 40.082 6.816 61.322 1.00 47.08 C +ANISOU 3860 CG MET B 113 6941 7156 3790 1219 -537 138 C +ATOM 3861 SD MET B 113 41.801 6.300 61.446 1.00 50.98 S +ANISOU 3861 SD MET B 113 7281 7717 4371 1284 -630 164 S +ATOM 3862 CE MET B 113 41.809 5.474 63.027 1.00 51.15 C +ANISOU 3862 CE MET B 113 7390 7747 4297 1365 -745 240 C +ATOM 3863 N ARG B 114 37.093 3.456 60.034 1.00 41.39 N +ANISOU 3863 N ARG B 114 6450 6224 3052 1298 -242 201 N +ATOM 3864 CA ARG B 114 36.142 2.374 60.318 1.00 41.29 C +ANISOU 3864 CA ARG B 114 6536 6134 3017 1321 -179 230 C +ATOM 3865 C ARG B 114 36.339 1.097 59.486 1.00 41.39 C +ANISOU 3865 C ARG B 114 6548 6087 3090 1345 -94 214 C +ATOM 3866 O ARG B 114 36.218 1.131 58.278 1.00 41.15 O +ANISOU 3866 O ARG B 114 6489 6067 3077 1275 -35 162 O +ATOM 3867 CB ARG B 114 34.715 2.879 60.073 1.00 40.43 C +ANISOU 3867 CB ARG B 114 6469 6013 2877 1237 -134 225 C +ATOM 3868 CG ARG B 114 33.645 1.888 60.510 1.00 40.40 C +ANISOU 3868 CG ARG B 114 6560 5933 2856 1245 -70 256 C +ATOM 3869 CD ARG B 114 32.260 2.398 60.193 1.00 39.66 C +ANISOU 3869 CD ARG B 114 6467 5835 2763 1161 -29 261 C +ATOM 3870 NE ARG B 114 32.016 3.741 60.723 1.00 39.26 N +ANISOU 3870 NE ARG B 114 6399 5815 2702 1148 -58 266 N +ATOM 3871 CZ ARG B 114 30.819 4.318 60.739 1.00 38.83 C +ANISOU 3871 CZ ARG B 114 6335 5744 2675 1103 -16 287 C +ATOM 3872 NH1 ARG B 114 29.745 3.662 60.280 1.00 39.08 N +ANISOU 3872 NH1 ARG B 114 6362 5747 2739 1057 35 312 N +ATOM 3873 NH2 ARG B 114 30.685 5.548 61.205 1.00 38.30 N +ANISOU 3873 NH2 ARG B 114 6254 5680 2618 1100 -19 283 N +ATOM 3874 N PRO B 115 36.595 -0.040 60.129 1.00 42.30 N +ANISOU 3874 N PRO B 115 6709 6130 3232 1437 -78 260 N +ATOM 3875 CA PRO B 115 36.726 -1.250 59.318 1.00 43.36 C +ANISOU 3875 CA PRO B 115 6855 6176 3440 1454 32 229 C +ATOM 3876 C PRO B 115 35.410 -1.698 58.684 1.00 43.37 C +ANISOU 3876 C PRO B 115 6940 6126 3410 1351 122 187 C +ATOM 3877 O PRO B 115 34.337 -1.384 59.181 1.00 42.87 O +ANISOU 3877 O PRO B 115 6929 6070 3290 1304 103 216 O +ATOM 3878 CB PRO B 115 37.206 -2.318 60.312 1.00 44.42 C +ANISOU 3878 CB PRO B 115 7025 6228 3624 1585 24 315 C +ATOM 3879 CG PRO B 115 37.460 -1.599 61.594 1.00 44.47 C +ANISOU 3879 CG PRO B 115 7030 6310 3555 1625 -114 390 C +ATOM 3880 CD PRO B 115 36.658 -0.338 61.562 1.00 43.36 C +ANISOU 3880 CD PRO B 115 6906 6247 3322 1516 -144 344 C +ATOM 3881 N ALA B 116 35.505 -2.435 57.585 1.00 44.27 N +ANISOU 3881 N ALA B 116 7063 6190 3566 1307 225 115 N +ATOM 3882 CA ALA B 116 34.326 -3.010 56.954 1.00 45.15 C +ANISOU 3882 CA ALA B 116 7253 6253 3646 1191 301 68 C +ATOM 3883 C ALA B 116 33.746 -4.148 57.796 1.00 46.35 C +ANISOU 3883 C ALA B 116 7501 6277 3830 1237 355 115 C +ATOM 3884 O ALA B 116 34.474 -4.898 58.446 1.00 47.12 O +ANISOU 3884 O ALA B 116 7616 6288 3997 1363 379 164 O +ATOM 3885 CB ALA B 116 34.650 -3.513 55.552 1.00 45.96 C +ANISOU 3885 CB ALA B 116 7363 6337 3761 1110 405 -41 C +ATOM 3886 N LEU B 117 32.428 -4.277 57.728 1.00 46.95 N +ANISOU 3886 N LEU B 117 7630 6341 3866 1130 375 110 N +ATOM 3887 CA LEU B 117 31.672 -5.330 58.385 1.00 48.41 C +ANISOU 3887 CA LEU B 117 7910 6402 4080 1135 445 147 C +ATOM 3888 C LEU B 117 31.378 -6.601 57.548 1.00 50.06 C +ANISOU 3888 C LEU B 117 8193 6488 4340 1051 574 61 C +ATOM 3889 O LEU B 117 31.100 -7.656 58.139 1.00 51.64 O +ANISOU 3889 O LEU B 117 8477 6546 4595 1086 654 96 O +ATOM 3890 CB LEU B 117 30.331 -4.757 58.826 1.00 48.51 C +ANISOU 3890 CB LEU B 117 7923 6464 4043 1054 409 190 C +ATOM 3891 CG LEU B 117 30.258 -4.169 60.235 1.00 48.92 C +ANISOU 3891 CG LEU B 117 7987 6539 4059 1147 356 288 C +ATOM 3892 CD1 LEU B 117 28.913 -3.475 60.431 1.00 48.25 C +ANISOU 3892 CD1 LEU B 117 7877 6502 3951 1058 352 309 C +ATOM 3893 CD2 LEU B 117 30.499 -5.268 61.276 1.00 50.03 C +ANISOU 3893 CD2 LEU B 117 8230 6557 4222 1247 409 363 C +ATOM 3894 N LYS B 118 31.398 -6.523 56.216 1.00 49.76 N +ANISOU 3894 N LYS B 118 8139 6495 4272 929 603 -51 N +ATOM 3895 CA LYS B 118 30.742 -7.590 55.412 1.00 51.50 C +ANISOU 3895 CA LYS B 118 8446 6618 4501 785 714 -152 C +ATOM 3896 C LYS B 118 31.364 -8.976 55.566 1.00 51.50 C +ANISOU 3896 C LYS B 118 8536 6416 4614 868 866 -187 C +ATOM 3897 O LYS B 118 30.671 -9.988 55.513 1.00 51.77 O +ANISOU 3897 O LYS B 118 8664 6320 4687 786 964 -227 O +ATOM 3898 CB LYS B 118 30.671 -7.241 53.921 1.00 52.94 C +ANISOU 3898 CB LYS B 118 8617 6903 4595 616 711 -271 C +ATOM 3899 CG LYS B 118 32.029 -7.192 53.249 1.00 54.89 C +ANISOU 3899 CG LYS B 118 8847 7151 4854 677 775 -344 C +ATOM 3900 CD LYS B 118 31.885 -7.208 51.754 1.00 56.92 C +ANISOU 3900 CD LYS B 118 9148 7471 5006 482 820 -481 C +ATOM 3901 CE LYS B 118 33.202 -7.542 51.091 1.00 59.08 C +ANISOU 3901 CE LYS B 118 9438 7690 5318 537 958 -581 C +ATOM 3902 NZ LYS B 118 33.134 -7.238 49.629 1.00 60.73 N +ANISOU 3902 NZ LYS B 118 9690 8009 5376 338 984 -702 N +ATOM 3903 N GLY B 119 32.677 -9.008 55.740 1.00 50.73 N +ANISOU 3903 N GLY B 119 8399 6286 4588 1028 890 -166 N +ATOM 3904 CA GLY B 119 33.384 -10.256 55.936 1.00 51.31 C +ANISOU 3904 CA GLY B 119 8531 6156 4805 1142 1035 -172 C +ATOM 3905 C GLY B 119 32.927 -10.955 57.201 1.00 51.03 C +ANISOU 3905 C GLY B 119 8561 5996 4830 1231 1041 -39 C +ATOM 3906 O GLY B 119 32.684 -12.150 57.198 1.00 53.04 O +ANISOU 3906 O GLY B 119 8916 6059 5177 1219 1181 -64 O +ATOM 3907 N ALA B 120 32.785 -10.191 58.278 1.00 48.89 N +ANISOU 3907 N ALA B 120 8245 5829 4498 1306 899 96 N +ATOM 3908 CA ALA B 120 32.380 -10.702 59.563 1.00 47.80 C +ANISOU 3908 CA ALA B 120 8177 5604 4381 1386 894 238 C +ATOM 3909 C ALA B 120 30.936 -11.171 59.528 1.00 47.07 C +ANISOU 3909 C ALA B 120 8172 5450 4261 1228 962 206 C +ATOM 3910 O ALA B 120 30.605 -12.254 60.018 1.00 47.85 O +ANISOU 3910 O ALA B 120 8370 5373 4435 1246 1067 256 O +ATOM 3911 CB ALA B 120 32.570 -9.622 60.605 1.00 46.61 C +ANISOU 3911 CB ALA B 120 7968 5605 4135 1469 731 358 C +ATOM 3912 N ILE B 121 30.073 -10.372 58.935 1.00 45.78 N +ANISOU 3912 N ILE B 121 7962 5426 4006 1070 904 134 N +ATOM 3913 CA ILE B 121 28.673 -10.758 58.807 1.00 46.63 C +ANISOU 3913 CA ILE B 121 8117 5497 4104 903 956 103 C +ATOM 3914 C ILE B 121 28.486 -12.057 58.016 1.00 48.65 C +ANISOU 3914 C ILE B 121 8466 5577 4439 795 1109 -13 C +ATOM 3915 O ILE B 121 27.731 -12.943 58.453 1.00 49.12 O +ANISOU 3915 O ILE B 121 8609 5496 4557 742 1202 13 O +ATOM 3916 CB ILE B 121 27.842 -9.661 58.154 1.00 45.99 C +ANISOU 3916 CB ILE B 121 7940 5602 3931 754 853 55 C +ATOM 3917 CG1 ILE B 121 27.782 -8.441 59.081 1.00 45.21 C +ANISOU 3917 CG1 ILE B 121 7768 5635 3772 845 738 166 C +ATOM 3918 CG2 ILE B 121 26.416 -10.150 57.909 1.00 46.61 C +ANISOU 3918 CG2 ILE B 121 8039 5644 4024 567 901 22 C +ATOM 3919 CD1 ILE B 121 27.352 -7.177 58.358 1.00 44.43 C +ANISOU 3919 CD1 ILE B 121 7554 5715 3609 749 630 133 C +ATOM 3920 N LEU B 122 29.175 -12.181 56.872 1.00 48.97 N +ANISOU 3920 N LEU B 122 8505 5616 4484 754 1152 -147 N +ATOM 3921 CA LEU B 122 29.067 -13.388 56.059 1.00 50.85 C +ANISOU 3921 CA LEU B 122 8851 5680 4789 637 1318 -289 C +ATOM 3922 C LEU B 122 29.601 -14.613 56.783 1.00 52.11 C +ANISOU 3922 C LEU B 122 9105 5584 5108 788 1466 -226 C +ATOM 3923 O LEU B 122 29.048 -15.704 56.633 1.00 53.05 O +ANISOU 3923 O LEU B 122 9333 5517 5302 687 1608 -288 O +ATOM 3924 CB LEU B 122 29.821 -13.237 54.741 1.00 51.93 C +ANISOU 3924 CB LEU B 122 8980 5863 4885 575 1359 -450 C +ATOM 3925 CG LEU B 122 29.258 -12.259 53.707 1.00 51.31 C +ANISOU 3925 CG LEU B 122 8842 6011 4643 379 1239 -534 C +ATOM 3926 CD1 LEU B 122 30.350 -11.932 52.688 1.00 51.76 C +ANISOU 3926 CD1 LEU B 122 8885 6125 4655 388 1278 -643 C +ATOM 3927 CD2 LEU B 122 28.034 -12.863 53.021 1.00 52.43 C +ANISOU 3927 CD2 LEU B 122 9057 6126 4735 116 1274 -646 C +ATOM 3928 N SER B 123 30.686 -14.449 57.540 1.00 51.90 N +ANISOU 3928 N SER B 123 9033 5544 5143 1022 1432 -97 N +ATOM 3929 CA SER B 123 31.213 -15.543 58.352 1.00 53.95 C +ANISOU 3929 CA SER B 123 9365 5571 5561 1191 1543 15 C +ATOM 3930 C SER B 123 30.213 -16.050 59.378 1.00 54.98 C +ANISOU 3930 C SER B 123 9581 5612 5698 1166 1560 139 C +ATOM 3931 O SER B 123 30.074 -17.262 59.560 1.00 57.14 O +ANISOU 3931 O SER B 123 9965 5644 6102 1174 1718 155 O +ATOM 3932 CB SER B 123 32.474 -15.114 59.080 1.00 53.69 C +ANISOU 3932 CB SER B 123 9239 5590 5569 1435 1447 165 C +ATOM 3933 OG SER B 123 33.593 -15.218 58.245 1.00 54.98 O +ANISOU 3933 OG SER B 123 9345 5718 5825 1503 1520 71 O +ATOM 3934 N LEU B 124 29.526 -15.138 60.055 1.00 54.02 N +ANISOU 3934 N LEU B 124 9411 5667 5445 1136 1420 227 N +ATOM 3935 CA LEU B 124 28.564 -15.564 61.044 1.00 55.58 C +ANISOU 3935 CA LEU B 124 9688 5788 5641 1106 1455 344 C +ATOM 3936 C LEU B 124 27.272 -16.111 60.461 1.00 56.93 C +ANISOU 3936 C LEU B 124 9911 5889 5831 870 1557 226 C +ATOM 3937 O LEU B 124 26.639 -16.966 61.080 1.00 58.89 O +ANISOU 3937 O LEU B 124 10254 5973 6145 839 1664 296 O +ATOM 3938 CB LEU B 124 28.265 -14.445 62.030 1.00 54.56 C +ANISOU 3938 CB LEU B 124 9501 5853 5375 1155 1305 470 C +ATOM 3939 CG LEU B 124 29.362 -14.345 63.080 1.00 54.86 C +ANISOU 3939 CG LEU B 124 9544 5894 5403 1381 1229 642 C +ATOM 3940 CD1 LEU B 124 29.355 -12.948 63.613 1.00 53.59 C +ANISOU 3940 CD1 LEU B 124 9304 5967 5087 1403 1064 686 C +ATOM 3941 CD2 LEU B 124 29.134 -15.345 64.191 1.00 56.40 C +ANISOU 3941 CD2 LEU B 124 9871 5911 5647 1453 1316 812 C +ATOM 3942 N LEU B 125 26.863 -15.631 59.292 1.00 57.07 N +ANISOU 3942 N LEU B 125 9865 6029 5787 692 1517 59 N +ATOM 3943 CA LEU B 125 25.738 -16.242 58.610 1.00 58.51 C +ANISOU 3943 CA LEU B 125 10091 6147 5992 447 1600 -65 C +ATOM 3944 C LEU B 125 26.089 -17.690 58.288 1.00 61.68 C +ANISOU 3944 C LEU B 125 10633 6264 6535 433 1800 -146 C +ATOM 3945 O LEU B 125 25.277 -18.588 58.492 1.00 63.82 O +ANISOU 3945 O LEU B 125 10990 6372 6883 316 1917 -153 O +ATOM 3946 CB LEU B 125 25.362 -15.470 57.350 1.00 57.70 C +ANISOU 3946 CB LEU B 125 9899 6243 5780 259 1497 -217 C +ATOM 3947 CG LEU B 125 24.825 -14.055 57.577 1.00 55.53 C +ANISOU 3947 CG LEU B 125 9478 6224 5395 250 1316 -138 C +ATOM 3948 CD1 LEU B 125 24.725 -13.300 56.254 1.00 54.87 C +ANISOU 3948 CD1 LEU B 125 9312 6328 5207 97 1208 -263 C +ATOM 3949 CD2 LEU B 125 23.481 -14.108 58.284 1.00 55.70 C +ANISOU 3949 CD2 LEU B 125 9473 6245 5444 155 1323 -55 C +ATOM 3950 N SER B 126 27.317 -17.930 57.842 1.00 62.89 N +ANISOU 3950 N SER B 126 10808 6343 6744 560 1857 -199 N +ATOM 3951 CA SER B 126 27.727 -19.295 57.510 1.00 65.72 C +ANISOU 3951 CA SER B 126 11299 6404 7266 565 2076 -283 C +ATOM 3952 C SER B 126 27.907 -20.159 58.776 1.00 67.16 C +ANISOU 3952 C SER B 126 11562 6359 7595 747 2169 -80 C +ATOM 3953 O SER B 126 27.466 -21.296 58.800 1.00 68.90 O +ANISOU 3953 O SER B 126 11905 6332 7939 667 2343 -112 O +ATOM 3954 CB SER B 126 28.977 -19.303 56.617 1.00 66.14 C +ANISOU 3954 CB SER B 126 11340 6431 7358 649 2139 -406 C +ATOM 3955 OG SER B 126 30.187 -19.219 57.349 1.00 66.45 O +ANISOU 3955 OG SER B 126 11325 6430 7492 939 2120 -243 O +ATOM 3956 N TYR B 127 28.514 -19.603 59.825 1.00 66.39 N +ANISOU 3956 N TYR B 127 11401 6352 7473 973 2048 130 N +ATOM 3957 CA TYR B 127 28.743 -20.332 61.083 1.00 67.90 C +ANISOU 3957 CA TYR B 127 11669 6360 7768 1152 2103 357 C +ATOM 3958 C TYR B 127 27.452 -20.742 61.809 1.00 68.47 C +ANISOU 3958 C TYR B 127 11827 6364 7822 1024 2155 437 C +ATOM 3959 O TYR B 127 27.388 -21.826 62.358 1.00 70.46 O +ANISOU 3959 O TYR B 127 12199 6364 8208 1073 2300 539 O +ATOM 3960 CB TYR B 127 29.627 -19.502 62.018 1.00 67.08 C +ANISOU 3960 CB TYR B 127 11475 6421 7592 1384 1923 556 C +ATOM 3961 CG TYR B 127 29.719 -20.034 63.423 1.00 68.30 C +ANISOU 3961 CG TYR B 127 11708 6458 7783 1542 1926 819 C +ATOM 3962 CD1 TYR B 127 30.571 -21.083 63.732 1.00 70.81 C +ANISOU 3962 CD1 TYR B 127 12083 6527 8293 1724 2033 946 C +ATOM 3963 CD2 TYR B 127 28.950 -19.486 64.447 1.00 67.75 C +ANISOU 3963 CD2 TYR B 127 11659 6525 7557 1508 1831 951 C +ATOM 3964 CE1 TYR B 127 30.651 -21.584 65.030 1.00 72.46 C +ANISOU 3964 CE1 TYR B 127 12374 6635 8522 1865 2021 1216 C +ATOM 3965 CE2 TYR B 127 29.025 -19.976 65.745 1.00 68.99 C +ANISOU 3965 CE2 TYR B 127 11912 6586 7714 1636 1836 1198 C +ATOM 3966 CZ TYR B 127 29.876 -21.020 66.030 1.00 71.40 C +ANISOU 3966 CZ TYR B 127 12277 6655 8195 1812 1918 1339 C +ATOM 3967 OH TYR B 127 29.955 -21.508 67.315 1.00 73.55 O +ANISOU 3967 OH TYR B 127 12650 6840 8453 1936 1909 1611 O +ATOM 3968 N TYR B 128 26.449 -19.871 61.825 1.00 66.77 N +ANISOU 3968 N TYR B 128 11544 6366 7457 869 2046 402 N +ATOM 3969 CA TYR B 128 25.109 -20.212 62.323 1.00 67.76 C +ANISOU 3969 CA TYR B 128 11723 6442 7580 709 2114 441 C +ATOM 3970 C TYR B 128 24.214 -20.950 61.323 1.00 69.22 C +ANISOU 3970 C TYR B 128 11951 6507 7843 441 2243 240 C +ATOM 3971 O TYR B 128 23.069 -21.239 61.641 1.00 68.95 O +ANISOU 3971 O TYR B 128 11937 6434 7824 284 2302 259 O +ATOM 3972 CB TYR B 128 24.351 -18.952 62.742 1.00 66.62 C +ANISOU 3972 CB TYR B 128 11465 6572 7273 653 1961 486 C +ATOM 3973 CG TYR B 128 24.879 -18.225 63.954 1.00 66.31 C +ANISOU 3973 CG TYR B 128 11413 6653 7127 858 1849 684 C +ATOM 3974 CD1 TYR B 128 25.377 -18.918 65.061 1.00 67.66 C +ANISOU 3974 CD1 TYR B 128 11701 6668 7335 1026 1907 885 C +ATOM 3975 CD2 TYR B 128 24.839 -16.834 64.009 1.00 64.94 C +ANISOU 3975 CD2 TYR B 128 11117 6747 6810 870 1684 675 C +ATOM 3976 CE1 TYR B 128 25.840 -18.247 66.175 1.00 67.62 C +ANISOU 3976 CE1 TYR B 128 11698 6793 7201 1185 1788 1062 C +ATOM 3977 CE2 TYR B 128 25.315 -16.151 65.111 1.00 64.73 C +ANISOU 3977 CE2 TYR B 128 11094 6830 6670 1031 1585 833 C +ATOM 3978 CZ TYR B 128 25.816 -16.863 66.191 1.00 66.31 C +ANISOU 3978 CZ TYR B 128 11418 6893 6883 1180 1630 1021 C +ATOM 3979 OH TYR B 128 26.263 -16.183 67.295 1.00 66.43 O +ANISOU 3979 OH TYR B 128 11449 7034 6754 1312 1518 1173 O +ATOM 3980 N LYS B 129 24.719 -21.210 60.118 1.00 70.45 N +ANISOU 3980 N LYS B 129 12115 6615 8035 374 2287 43 N +ATOM 3981 CA LYS B 129 23.985 -21.921 59.066 1.00 72.74 C +ANISOU 3981 CA LYS B 129 12464 6798 8374 97 2402 -176 C +ATOM 3982 C LYS B 129 22.679 -21.249 58.644 1.00 72.82 C +ANISOU 3982 C LYS B 129 12367 7030 8269 -161 2283 -255 C +ATOM 3983 O LYS B 129 21.700 -21.931 58.359 1.00 75.46 O +ANISOU 3983 O LYS B 129 12745 7263 8661 -394 2372 -344 O +ATOM 3984 CB LYS B 129 23.717 -23.378 59.485 1.00 75.28 C +ANISOU 3984 CB LYS B 129 12949 6771 8883 66 2632 -145 C +ATOM 3985 N TRP B 130 22.671 -19.922 58.582 1.00 71.39 N +ANISOU 3985 N TRP B 130 12037 7142 7943 -123 2084 -220 N +ATOM 3986 CA TRP B 130 21.471 -19.172 58.182 1.00 71.05 C +ANISOU 3986 CA TRP B 130 11860 7322 7812 -340 1955 -265 C +ATOM 3987 C TRP B 130 21.243 -19.281 56.679 1.00 71.50 C +ANISOU 3987 C TRP B 130 11911 7440 7813 -591 1926 -496 C +ATOM 3988 O TRP B 130 21.895 -18.584 55.908 1.00 70.63 O +ANISOU 3988 O TRP B 130 11756 7484 7596 -566 1824 -571 O +ATOM 3989 CB TRP B 130 21.608 -17.679 58.545 1.00 69.14 C +ANISOU 3989 CB TRP B 130 11466 7356 7449 -207 1762 -153 C +ATOM 3990 CG TRP B 130 21.403 -17.340 60.001 1.00 68.55 C +ANISOU 3990 CG TRP B 130 11375 7289 7380 -44 1762 56 C +ATOM 3991 CD1 TRP B 130 21.617 -18.154 61.073 1.00 69.64 C +ANISOU 3991 CD1 TRP B 130 11640 7224 7595 82 1895 188 C +ATOM 3992 CD2 TRP B 130 20.975 -16.081 60.538 1.00 67.19 C +ANISOU 3992 CD2 TRP B 130 11069 7336 7124 6 1633 157 C +ATOM 3993 NE1 TRP B 130 21.326 -17.495 62.235 1.00 69.43 N +ANISOU 3993 NE1 TRP B 130 11577 7292 7511 190 1854 356 N +ATOM 3994 CE2 TRP B 130 20.922 -16.220 61.933 1.00 67.96 C +ANISOU 3994 CE2 TRP B 130 11232 7356 7234 145 1705 329 C +ATOM 3995 CE3 TRP B 130 20.598 -14.861 59.974 1.00 65.71 C +ANISOU 3995 CE3 TRP B 130 10718 7390 6856 -58 1475 123 C +ATOM 3996 CZ2 TRP B 130 20.550 -15.177 62.765 1.00 66.51 C +ANISOU 3996 CZ2 TRP B 130 10967 7326 6976 217 1638 440 C +ATOM 3997 CZ3 TRP B 130 20.207 -13.830 60.809 1.00 64.04 C +ANISOU 3997 CZ3 TRP B 130 10411 7314 6603 26 1412 245 C +ATOM 3998 CH2 TRP B 130 20.188 -13.993 62.179 1.00 64.87 C +ANISOU 3998 CH2 TRP B 130 10595 7336 6715 158 1501 388 C +ATOM 3999 N GLU B 131 20.323 -20.138 56.262 1.00 72.78 N +ANISOU 3999 N GLU B 131 12125 7490 8037 -848 2014 -607 N +ATOM 4000 CA GLU B 131 20.001 -20.243 54.837 1.00 73.49 C +ANISOU 4000 CA GLU B 131 12221 7661 8042 -1130 1968 -831 C +ATOM 4001 C GLU B 131 18.649 -19.631 54.490 1.00 72.31 C +ANISOU 4001 C GLU B 131 11902 7741 7831 -1374 1798 -826 C +ATOM 4002 O GLU B 131 18.293 -19.499 53.314 1.00 72.62 O +ANISOU 4002 O GLU B 131 11913 7915 7762 -1619 1699 -979 O +ATOM 4003 CB GLU B 131 20.019 -21.697 54.401 1.00 77.06 C +ANISOU 4003 CB GLU B 131 12863 7816 8597 -1287 2187 -1004 C +ATOM 4004 CG GLU B 131 21.306 -22.435 54.744 1.00 78.06 C +ANISOU 4004 CG GLU B 131 13148 7674 8838 -1041 2383 -997 C +ATOM 4005 CD GLU B 131 21.256 -23.880 54.291 1.00 81.41 C +ANISOU 4005 CD GLU B 131 13766 7776 9389 -1205 2624 -1177 C +ATOM 4006 OE1 GLU B 131 20.743 -24.118 53.173 1.00 83.53 O +ANISOU 4006 OE1 GLU B 131 14075 8087 9575 -1514 2619 -1403 O +ATOM 4007 OE2 GLU B 131 21.721 -24.772 55.043 1.00 82.75 O +ANISOU 4007 OE2 GLU B 131 14052 7649 9738 -1035 2817 -1091 O +ATOM 4008 N LYS B 132 17.892 -19.265 55.509 1.00 70.35 N +ANISOU 4008 N LYS B 132 11538 7539 7651 -1311 1767 -646 N +ATOM 4009 CA LYS B 132 16.612 -18.631 55.291 1.00 69.27 C +ANISOU 4009 CA LYS B 132 11204 7614 7499 -1505 1614 -609 C +ATOM 4010 C LYS B 132 16.472 -17.569 56.348 1.00 66.04 C +ANISOU 4010 C LYS B 132 10654 7335 7102 -1284 1544 -396 C +ATOM 4011 O LYS B 132 16.441 -17.908 57.539 1.00 66.02 O +ANISOU 4011 O LYS B 132 10705 7187 7190 -1140 1677 -270 O +ATOM 4012 CB LYS B 132 15.491 -19.655 55.431 1.00 71.87 C +ANISOU 4012 CB LYS B 132 11549 7795 7961 -1747 1726 -649 C +ATOM 4013 CG LYS B 132 14.110 -19.053 55.311 1.00 72.41 C +ANISOU 4013 CG LYS B 132 11380 8073 8059 -1941 1578 -586 C +ATOM 4014 CD LYS B 132 13.027 -19.983 55.800 1.00 74.63 C +ANISOU 4014 CD LYS B 132 11651 8195 8507 -2125 1714 -573 C +ATOM 4015 CE LYS B 132 11.668 -19.326 55.637 1.00 75.36 C +ANISOU 4015 CE LYS B 132 11466 8513 8652 -2311 1557 -501 C +ATOM 4016 NZ LYS B 132 10.601 -20.344 55.838 1.00 78.34 N +ANISOU 4016 NZ LYS B 132 11828 8742 9193 -2562 1681 -534 N +ATOM 4017 N PHE B 133 16.405 -16.302 55.930 1.00 62.77 N +ANISOU 4017 N PHE B 133 10076 7181 6592 -1260 1348 -355 N +ATOM 4018 CA PHE B 133 16.313 -15.186 56.868 1.00 59.31 C +ANISOU 4018 CA PHE B 133 9508 6863 6160 -1053 1289 -174 C +ATOM 4019 C PHE B 133 15.852 -13.890 56.246 1.00 58.07 C +ANISOU 4019 C PHE B 133 9141 6978 5945 -1104 1079 -135 C +ATOM 4020 O PHE B 133 15.827 -13.741 55.025 1.00 58.42 O +ANISOU 4020 O PHE B 133 9149 7146 5901 -1270 949 -236 O +ATOM 4021 CB PHE B 133 17.652 -14.963 57.567 1.00 57.28 C +ANISOU 4021 CB PHE B 133 9373 6539 5851 -757 1339 -116 C +ATOM 4022 CG PHE B 133 18.778 -14.546 56.667 1.00 56.16 C +ANISOU 4022 CG PHE B 133 9269 6480 5589 -698 1247 -209 C +ATOM 4023 CD1 PHE B 133 19.587 -15.491 56.054 1.00 57.22 C +ANISOU 4023 CD1 PHE B 133 9566 6463 5711 -727 1344 -349 C +ATOM 4024 CD2 PHE B 133 19.078 -13.208 56.491 1.00 54.16 C +ANISOU 4024 CD2 PHE B 133 8893 6437 5248 -599 1091 -153 C +ATOM 4025 CE1 PHE B 133 20.647 -15.107 55.252 1.00 56.38 C +ANISOU 4025 CE1 PHE B 133 9490 6427 5501 -668 1288 -435 C +ATOM 4026 CE2 PHE B 133 20.130 -12.813 55.698 1.00 53.33 C +ANISOU 4026 CE2 PHE B 133 8821 6405 5036 -546 1023 -230 C +ATOM 4027 CZ PHE B 133 20.919 -13.764 55.082 1.00 54.75 C +ANISOU 4027 CZ PHE B 133 9156 6444 5199 -580 1124 -372 C +ATOM 4028 N VAL B 134 15.495 -12.949 57.112 1.00 56.55 N +ANISOU 4028 N VAL B 134 8818 6869 5797 -958 1056 17 N +ATOM 4029 CA VAL B 134 15.036 -11.626 56.706 1.00 55.19 C +ANISOU 4029 CA VAL B 134 8431 6927 5609 -962 879 90 C +ATOM 4030 C VAL B 134 16.196 -10.684 56.821 1.00 52.41 C +ANISOU 4030 C VAL B 134 8120 6642 5148 -737 819 118 C +ATOM 4031 O VAL B 134 17.009 -10.799 57.727 1.00 50.93 O +ANISOU 4031 O VAL B 134 8062 6345 4942 -539 923 149 O +ATOM 4032 CB VAL B 134 13.921 -11.110 57.632 1.00 55.59 C +ANISOU 4032 CB VAL B 134 8309 7007 5806 -931 924 234 C +ATOM 4033 CG1 VAL B 134 13.421 -9.743 57.192 1.00 54.87 C +ANISOU 4033 CG1 VAL B 134 7982 7129 5736 -923 753 322 C +ATOM 4034 CG2 VAL B 134 12.767 -12.108 57.697 1.00 58.07 C +ANISOU 4034 CG2 VAL B 134 8576 7232 6255 -1148 1013 218 C +ATOM 4035 N TYR B 135 16.263 -9.739 55.905 1.00 51.72 N +ANISOU 4035 N TYR B 135 7918 6741 4991 -775 645 119 N +ATOM 4036 CA TYR B 135 17.353 -8.791 55.888 1.00 50.18 C +ANISOU 4036 CA TYR B 135 7749 6618 4698 -587 582 140 C +ATOM 4037 C TYR B 135 16.763 -7.403 55.766 1.00 50.08 C +ANISOU 4037 C TYR B 135 7527 6779 4722 -561 448 257 C +ATOM 4038 O TYR B 135 16.285 -7.012 54.704 1.00 50.27 O +ANISOU 4038 O TYR B 135 7429 6950 4721 -713 295 263 O +ATOM 4039 CB TYR B 135 18.318 -9.111 54.758 1.00 49.84 C +ANISOU 4039 CB TYR B 135 7822 6595 4517 -652 532 6 C +ATOM 4040 CG TYR B 135 19.376 -8.064 54.534 1.00 48.08 C +ANISOU 4040 CG TYR B 135 7596 6472 4198 -498 451 26 C +ATOM 4041 CD1 TYR B 135 20.175 -7.601 55.574 1.00 46.47 C +ANISOU 4041 CD1 TYR B 135 7435 6215 4007 -258 509 89 C +ATOM 4042 CD2 TYR B 135 19.591 -7.532 53.270 1.00 48.30 C +ANISOU 4042 CD2 TYR B 135 7585 6652 4113 -607 313 -16 C +ATOM 4043 CE1 TYR B 135 21.152 -6.645 55.356 1.00 44.84 C +ANISOU 4043 CE1 TYR B 135 7217 6095 3722 -135 435 100 C +ATOM 4044 CE2 TYR B 135 20.566 -6.567 53.050 1.00 46.65 C +ANISOU 4044 CE2 TYR B 135 7371 6526 3825 -476 252 5 C +ATOM 4045 CZ TYR B 135 21.344 -6.134 54.092 1.00 44.77 C +ANISOU 4045 CZ TYR B 135 7163 6224 3622 -242 315 58 C +ATOM 4046 OH TYR B 135 22.284 -5.181 53.828 1.00 43.34 O +ANISOU 4046 OH TYR B 135 6967 6126 3372 -136 252 73 O +ATOM 4047 N LEU B 136 16.745 -6.695 56.891 1.00 50.24 N +ANISOU 4047 N LEU B 136 7508 6773 4805 -376 514 357 N +ATOM 4048 CA LEU B 136 16.229 -5.342 56.941 1.00 50.66 C +ANISOU 4048 CA LEU B 136 7371 6950 4926 -317 429 471 C +ATOM 4049 C LEU B 136 17.413 -4.404 56.849 1.00 49.54 C +ANISOU 4049 C LEU B 136 7284 6860 4678 -161 367 467 C +ATOM 4050 O LEU B 136 18.374 -4.557 57.596 1.00 47.89 O +ANISOU 4050 O LEU B 136 7224 6563 4406 -14 452 435 O +ATOM 4051 CB LEU B 136 15.506 -5.105 58.253 1.00 51.15 C +ANISOU 4051 CB LEU B 136 7376 6936 5121 -219 572 561 C +ATOM 4052 CG LEU B 136 14.365 -6.048 58.631 1.00 53.32 C +ANISOU 4052 CG LEU B 136 7604 7131 5522 -349 683 575 C +ATOM 4053 CD1 LEU B 136 13.826 -5.625 59.988 1.00 53.32 C +ANISOU 4053 CD1 LEU B 136 7567 7061 5629 -222 850 662 C +ATOM 4054 CD2 LEU B 136 13.237 -6.035 57.603 1.00 55.28 C +ANISOU 4054 CD2 LEU B 136 7635 7497 5871 -561 551 606 C +ATOM 4055 N TYR B 137 17.357 -3.429 55.947 1.00 50.20 N +ANISOU 4055 N TYR B 137 7240 7087 4744 -196 215 513 N +ATOM 4056 CA TYR B 137 18.507 -2.542 55.736 1.00 50.00 C +ANISOU 4056 CA TYR B 137 7265 7112 4621 -71 156 505 C +ATOM 4057 C TYR B 137 18.121 -1.116 55.392 1.00 50.07 C +ANISOU 4057 C TYR B 137 7097 7234 4693 -39 47 622 C +ATOM 4058 O TYR B 137 17.039 -0.875 54.893 1.00 50.45 O +ANISOU 4058 O TYR B 137 6973 7359 4836 -147 -35 709 O +ATOM 4059 CB TYR B 137 19.404 -3.102 54.623 1.00 50.50 C +ANISOU 4059 CB TYR B 137 7445 7211 4530 -164 93 393 C +ATOM 4060 CG TYR B 137 18.762 -3.065 53.267 1.00 52.01 C +ANISOU 4060 CG TYR B 137 7541 7541 4679 -374 -55 402 C +ATOM 4061 CD1 TYR B 137 17.864 -4.057 52.886 1.00 54.17 C +ANISOU 4061 CD1 TYR B 137 7799 7809 4975 -570 -60 361 C +ATOM 4062 CD2 TYR B 137 19.032 -2.035 52.370 1.00 52.01 C +ANISOU 4062 CD2 TYR B 137 7469 7682 4610 -391 -197 459 C +ATOM 4063 CE1 TYR B 137 17.245 -4.032 51.645 1.00 55.86 C +ANISOU 4063 CE1 TYR B 137 7926 8169 5128 -789 -221 372 C +ATOM 4064 CE2 TYR B 137 18.434 -2.009 51.119 1.00 53.62 C +ANISOU 4064 CE2 TYR B 137 7595 8030 4747 -598 -353 485 C +ATOM 4065 CZ TYR B 137 17.539 -3.003 50.760 1.00 55.57 C +ANISOU 4065 CZ TYR B 137 7825 8285 5002 -800 -374 440 C +ATOM 4066 OH TYR B 137 16.915 -2.985 49.525 1.00 58.04 O +ANISOU 4066 OH TYR B 137 8062 8761 5230 -1030 -552 469 O +ATOM 4067 N ASP B 138 19.015 -0.183 55.709 1.00 50.38 N +ANISOU 4067 N ASP B 138 7174 7272 4696 111 49 632 N +ATOM 4068 CA ASP B 138 18.984 1.154 55.151 1.00 52.35 C +ANISOU 4068 CA ASP B 138 7295 7617 4977 139 -59 728 C +ATOM 4069 C ASP B 138 20.305 1.368 54.407 1.00 52.61 C +ANISOU 4069 C ASP B 138 7435 7701 4851 148 -126 662 C +ATOM 4070 O ASP B 138 21.189 0.519 54.453 1.00 51.68 O +ANISOU 4070 O ASP B 138 7471 7535 4627 154 -73 546 O +ATOM 4071 CB ASP B 138 18.686 2.237 56.209 1.00 52.90 C +ANISOU 4071 CB ASP B 138 7288 7625 5184 296 25 806 C +ATOM 4072 CG ASP B 138 19.772 2.381 57.285 1.00 53.05 C +ANISOU 4072 CG ASP B 138 7471 7554 5132 447 134 726 C +ATOM 4073 OD1 ASP B 138 20.952 2.087 57.018 1.00 54.16 O +ANISOU 4073 OD1 ASP B 138 7738 7705 5135 463 102 645 O +ATOM 4074 OD2 ASP B 138 19.459 2.829 58.415 1.00 54.20 O +ANISOU 4074 OD2 ASP B 138 7614 7621 5358 548 252 747 O +ATOM 4075 N THR B 139 20.429 2.486 53.706 1.00 53.80 N +ANISOU 4075 N THR B 139 7496 7942 5001 150 -233 744 N +ATOM 4076 CA THR B 139 21.573 2.704 52.841 1.00 54.62 C +ANISOU 4076 CA THR B 139 7686 8110 4957 129 -294 693 C +ATOM 4077 C THR B 139 22.595 3.680 53.414 1.00 54.88 C +ANISOU 4077 C THR B 139 7755 8099 4996 287 -251 689 C +ATOM 4078 O THR B 139 23.556 4.015 52.755 1.00 54.54 O +ANISOU 4078 O THR B 139 7761 8106 4856 279 -291 660 O +ATOM 4079 CB THR B 139 21.110 3.207 51.459 1.00 56.48 C +ANISOU 4079 CB THR B 139 7819 8492 5147 -15 -457 791 C +ATOM 4080 OG1 THR B 139 20.256 4.347 51.630 1.00 57.83 O +ANISOU 4080 OG1 THR B 139 7811 8681 5481 40 -510 960 O +ATOM 4081 CG2 THR B 139 20.361 2.101 50.682 1.00 57.40 C +ANISOU 4081 CG2 THR B 139 7938 8675 5194 -219 -521 755 C +ATOM 4082 N GLU B 140 22.415 4.109 54.655 1.00 57.95 N +ANISOU 4082 N GLU B 140 8129 8395 5492 418 -160 707 N +ATOM 4083 CA GLU B 140 23.216 5.196 55.205 1.00 59.16 C +ANISOU 4083 CA GLU B 140 8302 8512 5664 543 -131 709 C +ATOM 4084 C GLU B 140 24.689 4.868 55.449 1.00 58.81 C +ANISOU 4084 C GLU B 140 8396 8447 5500 599 -103 594 C +ATOM 4085 O GLU B 140 25.477 5.791 55.662 1.00 61.68 O +ANISOU 4085 O GLU B 140 8766 8804 5863 669 -106 590 O +ATOM 4086 CB GLU B 140 22.613 5.695 56.516 1.00 61.33 C +ANISOU 4086 CB GLU B 140 8547 8688 6064 649 -24 737 C +ATOM 4087 CG GLU B 140 21.226 6.315 56.391 1.00 65.14 C +ANISOU 4087 CG GLU B 140 8856 9172 6722 632 -28 867 C +ATOM 4088 CD GLU B 140 20.886 7.258 57.549 1.00 68.13 C +ANISOU 4088 CD GLU B 140 9208 9442 7234 753 100 888 C +ATOM 4089 OE1 GLU B 140 21.752 7.489 58.430 1.00 71.03 O +ANISOU 4089 OE1 GLU B 140 9705 9749 7532 833 173 796 O +ATOM 4090 OE2 GLU B 140 19.750 7.785 57.582 1.00 70.55 O +ANISOU 4090 OE2 GLU B 140 9360 9723 7721 764 131 994 O +ATOM 4091 N ARG B 141 25.067 3.590 55.445 1.00 57.16 N +ANISOU 4091 N ARG B 141 8286 8219 5211 571 -70 507 N +ATOM 4092 CA ARG B 141 26.478 3.232 55.585 1.00 55.10 C +ANISOU 4092 CA ARG B 141 8127 7939 4866 631 -47 416 C +ATOM 4093 C ARG B 141 27.028 2.683 54.275 1.00 53.61 C +ANISOU 4093 C ARG B 141 7968 7813 4586 531 -80 360 C +ATOM 4094 O ARG B 141 28.035 1.978 54.267 1.00 52.21 O +ANISOU 4094 O ARG B 141 7871 7605 4360 564 -33 276 O +ATOM 4095 CB ARG B 141 26.675 2.254 56.750 1.00 55.59 C +ANISOU 4095 CB ARG B 141 8290 7907 4925 710 37 369 C +ATOM 4096 CG ARG B 141 26.843 2.957 58.105 1.00 56.07 C +ANISOU 4096 CG ARG B 141 8371 7920 5011 826 71 389 C +ATOM 4097 CD ARG B 141 26.135 2.262 59.267 1.00 56.98 C +ANISOU 4097 CD ARG B 141 8549 7952 5145 861 160 403 C +ATOM 4098 NE ARG B 141 24.749 2.055 58.871 1.00 58.16 N +ANISOU 4098 NE ARG B 141 8623 8103 5372 772 182 450 N +ATOM 4099 CZ ARG B 141 24.198 0.880 58.597 1.00 58.47 C +ANISOU 4099 CZ ARG B 141 8686 8111 5416 697 213 437 C +ATOM 4100 NH1 ARG B 141 24.874 -0.253 58.768 1.00 59.75 N +ANISOU 4100 NH1 ARG B 141 8963 8217 5521 717 250 382 N +ATOM 4101 NH2 ARG B 141 22.941 0.842 58.188 1.00 58.43 N +ANISOU 4101 NH2 ARG B 141 8582 8125 5491 602 211 486 N +ATOM 4102 N GLY B 142 26.382 3.034 53.165 1.00 52.31 N +ANISOU 4102 N GLY B 142 7736 7738 4399 407 -156 413 N +ATOM 4103 CA GLY B 142 26.788 2.516 51.872 1.00 53.56 C +ANISOU 4103 CA GLY B 142 7944 7966 4440 281 -178 353 C +ATOM 4104 C GLY B 142 26.090 1.222 51.497 1.00 55.48 C +ANISOU 4104 C GLY B 142 8240 8194 4644 157 -156 291 C +ATOM 4105 O GLY B 142 25.242 0.724 52.242 1.00 56.19 O +ANISOU 4105 O GLY B 142 8316 8220 4813 169 -127 310 O +ATOM 4106 N PHE B 143 26.441 0.689 50.326 1.00 58.24 N +ANISOU 4106 N PHE B 143 8659 8598 4869 23 -157 211 N +ATOM 4107 CA PHE B 143 25.767 -0.475 49.725 1.00 60.05 C +ANISOU 4107 CA PHE B 143 8951 8826 5038 -143 -144 134 C +ATOM 4108 C PHE B 143 26.636 -1.727 49.757 1.00 57.57 C +ANISOU 4108 C PHE B 143 8780 8396 4695 -126 2 -25 C +ATOM 4109 O PHE B 143 26.266 -2.775 49.235 1.00 59.49 O +ANISOU 4109 O PHE B 143 9106 8609 4886 -268 47 -122 O +ATOM 4110 CB PHE B 143 25.394 -0.176 48.266 1.00 65.28 C +ANISOU 4110 CB PHE B 143 9604 9644 5556 -348 -256 154 C +ATOM 4111 CG PHE B 143 24.551 1.065 48.090 1.00 69.55 C +ANISOU 4111 CG PHE B 143 9989 10297 6137 -365 -412 340 C +ATOM 4112 CD1 PHE B 143 25.137 2.326 48.107 1.00 70.73 C +ANISOU 4112 CD1 PHE B 143 10081 10482 6309 -259 -445 432 C +ATOM 4113 CD2 PHE B 143 23.165 0.975 47.885 1.00 72.62 C +ANISOU 4113 CD2 PHE B 143 10277 10751 6563 -489 -523 429 C +ATOM 4114 CE1 PHE B 143 24.368 3.473 47.943 1.00 72.21 C +ANISOU 4114 CE1 PHE B 143 10125 10747 6562 -262 -573 614 C +ATOM 4115 CE2 PHE B 143 22.393 2.120 47.725 1.00 73.36 C +ANISOU 4115 CE2 PHE B 143 10206 10937 6730 -485 -662 621 C +ATOM 4116 CZ PHE B 143 22.996 3.372 47.761 1.00 73.37 C +ANISOU 4116 CZ PHE B 143 10162 10952 6760 -364 -681 715 C +ATOM 4117 N SER B 144 27.798 -1.608 50.376 1.00 54.39 N +ANISOU 4117 N SER B 144 8401 7923 4340 44 79 -49 N +ATOM 4118 CA SER B 144 28.744 -2.696 50.507 1.00 53.74 C +ANISOU 4118 CA SER B 144 8426 7717 4274 104 223 -171 C +ATOM 4119 C SER B 144 28.120 -4.010 51.061 1.00 52.77 C +ANISOU 4119 C SER B 144 8377 7455 4216 86 307 -218 C +ATOM 4120 O SER B 144 28.296 -5.099 50.479 1.00 53.41 O +ANISOU 4120 O SER B 144 8566 7458 4268 -2 413 -345 O +ATOM 4121 CB SER B 144 29.898 -2.211 51.403 1.00 53.49 C +ANISOU 4121 CB SER B 144 8358 7642 4321 314 249 -136 C +ATOM 4122 OG SER B 144 30.978 -3.126 51.418 1.00 55.42 O +ANISOU 4122 OG SER B 144 8673 7780 4602 390 379 -231 O +ATOM 4123 N VAL B 145 27.398 -3.908 52.173 1.00 49.81 N +ANISOU 4123 N VAL B 145 7954 7039 3930 163 278 -123 N +ATOM 4124 CA VAL B 145 26.830 -5.081 52.803 1.00 49.32 C +ANISOU 4124 CA VAL B 145 7961 6840 3939 154 366 -147 C +ATOM 4125 C VAL B 145 25.666 -5.614 51.985 1.00 50.10 C +ANISOU 4125 C VAL B 145 8070 6970 3996 -72 342 -194 C +ATOM 4126 O VAL B 145 25.528 -6.828 51.785 1.00 50.84 O +ANISOU 4126 O VAL B 145 8266 6948 4100 -159 445 -295 O +ATOM 4127 CB VAL B 145 26.375 -4.781 54.242 1.00 48.10 C +ANISOU 4127 CB VAL B 145 7761 6640 3874 289 357 -29 C +ATOM 4128 CG1 VAL B 145 25.704 -5.996 54.858 1.00 48.79 C +ANISOU 4128 CG1 VAL B 145 7922 6584 4029 262 456 -39 C +ATOM 4129 CG2 VAL B 145 27.562 -4.355 55.088 1.00 47.35 C +ANISOU 4129 CG2 VAL B 145 7671 6518 3800 491 367 7 C +ATOM 4130 N LEU B 146 24.811 -4.710 51.526 1.00 49.86 N +ANISOU 4130 N LEU B 146 7925 7090 3928 -174 204 -115 N +ATOM 4131 CA LEU B 146 23.679 -5.106 50.711 1.00 51.46 C +ANISOU 4131 CA LEU B 146 8108 7357 4085 -407 141 -139 C +ATOM 4132 C LEU B 146 24.105 -5.976 49.518 1.00 52.84 C +ANISOU 4132 C LEU B 146 8420 7523 4131 -580 197 -308 C +ATOM 4133 O LEU B 146 23.452 -6.984 49.250 1.00 54.71 O +ANISOU 4133 O LEU B 146 8720 7701 4364 -744 239 -393 O +ATOM 4134 CB LEU B 146 22.911 -3.880 50.240 1.00 51.99 C +ANISOU 4134 CB LEU B 146 8017 7605 4130 -475 -35 -6 C +ATOM 4135 CG LEU B 146 21.792 -4.047 49.193 1.00 54.53 C +ANISOU 4135 CG LEU B 146 8283 8053 4382 -734 -162 0 C +ATOM 4136 CD1 LEU B 146 20.700 -5.049 49.566 1.00 55.66 C +ANISOU 4136 CD1 LEU B 146 8414 8119 4614 -850 -126 -24 C +ATOM 4137 CD2 LEU B 146 21.180 -2.684 48.912 1.00 55.18 C +ANISOU 4137 CD2 LEU B 146 8185 8297 4483 -736 -337 179 C +ATOM 4138 N GLN B 147 25.189 -5.611 48.825 1.00 52.25 N +ANISOU 4138 N GLN B 147 8398 7497 3955 -555 216 -365 N +ATOM 4139 CA GLN B 147 25.626 -6.341 47.630 1.00 54.05 C +ANISOU 4139 CA GLN B 147 8769 7724 4043 -728 293 -537 C +ATOM 4140 C GLN B 147 26.239 -7.690 47.942 1.00 53.69 C +ANISOU 4140 C GLN B 147 8866 7459 4072 -677 505 -685 C +ATOM 4141 O GLN B 147 26.015 -8.655 47.221 1.00 55.45 O +ANISOU 4141 O GLN B 147 9213 7625 4228 -865 588 -838 O +ATOM 4142 CB GLN B 147 26.607 -5.504 46.823 1.00 55.10 C +ANISOU 4142 CB GLN B 147 8909 7971 4054 -712 275 -547 C +ATOM 4143 CG GLN B 147 25.931 -4.327 46.126 1.00 56.64 C +ANISOU 4143 CG GLN B 147 8997 8385 4138 -831 68 -416 C +ATOM 4144 CD GLN B 147 26.907 -3.315 45.518 1.00 57.52 C +ANISOU 4144 CD GLN B 147 9099 8600 4154 -784 49 -383 C +ATOM 4145 OE1 GLN B 147 26.506 -2.211 45.153 1.00 58.39 O +ANISOU 4145 OE1 GLN B 147 9109 8862 4212 -822 -109 -239 O +ATOM 4146 NE2 GLN B 147 28.187 -3.681 45.423 1.00 58.61 N +ANISOU 4146 NE2 GLN B 147 9330 8649 4290 -696 219 -504 N +ATOM 4147 N ALA B 148 27.016 -7.742 49.016 1.00 52.25 N +ANISOU 4147 N ALA B 148 8670 7152 4031 -428 590 -635 N +ATOM 4148 CA ALA B 148 27.615 -8.973 49.496 1.00 52.59 C +ANISOU 4148 CA ALA B 148 8825 6969 4187 -333 783 -725 C +ATOM 4149 C ALA B 148 26.526 -9.997 49.820 1.00 54.00 C +ANISOU 4149 C ALA B 148 9058 7030 4427 -452 827 -754 C +ATOM 4150 O ALA B 148 26.650 -11.176 49.486 1.00 54.90 O +ANISOU 4150 O ALA B 148 9308 6983 4566 -534 984 -897 O +ATOM 4151 CB ALA B 148 28.471 -8.688 50.724 1.00 50.91 C +ANISOU 4151 CB ALA B 148 8553 6681 4106 -48 806 -611 C +ATOM 4152 N ILE B 149 25.453 -9.533 50.455 1.00 54.07 N +ANISOU 4152 N ILE B 149 8960 7111 4472 -466 702 -621 N +ATOM 4153 CA ILE B 149 24.336 -10.407 50.790 1.00 56.33 C +ANISOU 4153 CA ILE B 149 9272 7301 4828 -590 737 -632 C +ATOM 4154 C ILE B 149 23.528 -10.836 49.565 1.00 59.40 C +ANISOU 4154 C ILE B 149 9704 7762 5102 -904 695 -759 C +ATOM 4155 O ILE B 149 23.095 -11.984 49.517 1.00 61.45 O +ANISOU 4155 O ILE B 149 10064 7875 5407 -1034 805 -863 O +ATOM 4156 CB ILE B 149 23.446 -9.828 51.933 1.00 54.92 C +ANISOU 4156 CB ILE B 149 8960 7161 4746 -501 651 -452 C +ATOM 4157 CG1 ILE B 149 23.965 -10.293 53.307 1.00 54.24 C +ANISOU 4157 CG1 ILE B 149 8925 6896 4787 -269 773 -381 C +ATOM 4158 CG2 ILE B 149 22.002 -10.336 51.874 1.00 55.96 C +ANISOU 4158 CG2 ILE B 149 9053 7292 4918 -709 624 -451 C +ATOM 4159 CD1 ILE B 149 25.312 -9.749 53.713 1.00 53.42 C +ANISOU 4159 CD1 ILE B 149 8823 6793 4680 -37 780 -339 C +ATOM 4160 N MET B 150 23.313 -9.947 48.599 1.00 61.40 N +ANISOU 4160 N MET B 150 9888 8234 5204 -1036 535 -746 N +ATOM 4161 CA MET B 150 22.625 -10.328 47.357 1.00 65.51 C +ANISOU 4161 CA MET B 150 10462 8851 5575 -1357 471 -866 C +ATOM 4162 C MET B 150 23.399 -11.432 46.633 1.00 67.51 C +ANISOU 4162 C MET B 150 10934 8958 5758 -1456 668 -1100 C +ATOM 4163 O MET B 150 22.824 -12.455 46.244 1.00 68.65 O +ANISOU 4163 O MET B 150 11183 9014 5884 -1675 735 -1241 O +ATOM 4164 CB MET B 150 22.486 -9.130 46.407 1.00 67.45 C +ANISOU 4164 CB MET B 150 10615 9362 5649 -1458 266 -791 C +ATOM 4165 CG MET B 150 21.330 -8.178 46.689 1.00 68.65 C +ANISOU 4165 CG MET B 150 10549 9679 5853 -1477 49 -586 C +ATOM 4166 SD MET B 150 21.275 -6.777 45.523 1.00 71.49 S +ANISOU 4166 SD MET B 150 10810 10330 6022 -1579 -185 -471 S +ATOM 4167 CE MET B 150 20.755 -7.601 44.015 1.00 73.78 C +ANISOU 4167 CE MET B 150 11233 10727 6071 -1982 -250 -642 C +ATOM 4168 N GLU B 151 24.705 -11.208 46.464 1.00 68.01 N +ANISOU 4168 N GLU B 151 11059 8987 5795 -1297 772 -1146 N +ATOM 4169 CA GLU B 151 25.574 -12.150 45.778 1.00 70.64 C +ANISOU 4169 CA GLU B 151 11585 9169 6083 -1357 992 -1365 C +ATOM 4170 C GLU B 151 25.648 -13.517 46.468 1.00 70.58 C +ANISOU 4170 C GLU B 151 11687 8865 6264 -1294 1208 -1451 C +ATOM 4171 O GLU B 151 25.585 -14.554 45.795 1.00 73.61 O +ANISOU 4171 O GLU B 151 12238 9119 6608 -1485 1359 -1656 O +ATOM 4172 CB GLU B 151 26.991 -11.578 45.635 1.00 71.99 C +ANISOU 4172 CB GLU B 151 11756 9353 6243 -1157 1071 -1364 C +ATOM 4173 CG GLU B 151 27.955 -12.514 44.894 1.00 75.83 C +ANISOU 4173 CG GLU B 151 12428 9675 6706 -1202 1331 -1595 C +ATOM 4174 CD GLU B 151 29.344 -11.921 44.720 1.00 77.46 C +ANISOU 4174 CD GLU B 151 12606 9904 6919 -1013 1415 -1587 C +ATOM 4175 OE1 GLU B 151 29.573 -10.769 45.178 1.00 79.95 O +ANISOU 4175 OE1 GLU B 151 12765 10363 7247 -857 1260 -1407 O +ATOM 4176 OE2 GLU B 151 30.208 -12.610 44.140 1.00 80.41 O +ANISOU 4176 OE2 GLU B 151 13111 10141 7300 -1023 1650 -1767 O +ATOM 4177 N ALA B 152 25.801 -13.518 47.792 1.00 66.55 N +ANISOU 4177 N ALA B 152 11096 8239 5948 -1034 1229 -1297 N +ATOM 4178 CA ALA B 152 25.908 -14.755 48.561 1.00 65.88 C +ANISOU 4178 CA ALA B 152 11108 7867 6055 -943 1426 -1331 C +ATOM 4179 C ALA B 152 24.600 -15.540 48.583 1.00 66.51 C +ANISOU 4179 C ALA B 152 11230 7881 6158 -1177 1424 -1379 C +ATOM 4180 O ALA B 152 24.614 -16.765 48.632 1.00 67.28 O +ANISOU 4180 O ALA B 152 11470 7735 6357 -1230 1619 -1499 O +ATOM 4181 CB ALA B 152 26.366 -14.463 49.979 1.00 63.93 C +ANISOU 4181 CB ALA B 152 10766 7551 5972 -624 1418 -1128 C +ATOM 4182 N ALA B 153 23.474 -14.838 48.547 1.00 65.48 N +ANISOU 4182 N ALA B 153 10966 7957 5953 -1314 1211 -1281 N +ATOM 4183 CA ALA B 153 22.167 -15.481 48.491 1.00 66.81 C +ANISOU 4183 CA ALA B 153 11138 8100 6145 -1563 1182 -1319 C +ATOM 4184 C ALA B 153 21.964 -16.239 47.185 1.00 69.29 C +ANISOU 4184 C ALA B 153 11609 8400 6317 -1891 1239 -1566 C +ATOM 4185 O ALA B 153 21.515 -17.389 47.194 1.00 71.96 O +ANISOU 4185 O ALA B 153 12064 8545 6732 -2045 1377 -1690 O +ATOM 4186 CB ALA B 153 21.075 -14.447 48.664 1.00 66.19 C +ANISOU 4186 CB ALA B 153 10848 8266 6033 -1625 934 -1146 C +ATOM 4187 N VAL B 154 22.296 -15.612 46.055 1.00 68.85 N +ANISOU 4187 N VAL B 154 11572 8541 6045 -2013 1144 -1643 N +ATOM 4188 CA VAL B 154 22.235 -16.321 44.775 1.00 71.17 C +ANISOU 4188 CA VAL B 154 12050 8826 6163 -2333 1216 -1899 C +ATOM 4189 C VAL B 154 23.175 -17.536 44.802 1.00 72.36 C +ANISOU 4189 C VAL B 154 12417 8649 6425 -2260 1547 -2096 C +ATOM 4190 O VAL B 154 22.769 -18.651 44.503 1.00 74.62 O +ANISOU 4190 O VAL B 154 12855 8762 6734 -2474 1687 -2280 O +ATOM 4191 CB VAL B 154 22.612 -15.427 43.565 1.00 70.97 C +ANISOU 4191 CB VAL B 154 12037 9062 5865 -2455 1086 -1943 C +ATOM 4192 CG1 VAL B 154 22.700 -16.266 42.302 1.00 74.16 C +ANISOU 4192 CG1 VAL B 154 12677 9426 6072 -2779 1210 -2235 C +ATOM 4193 CG2 VAL B 154 21.596 -14.317 43.360 1.00 70.13 C +ANISOU 4193 CG2 VAL B 154 11726 9270 5648 -2569 757 -1754 C +ATOM 4194 N GLN B 155 24.431 -17.315 45.164 1.00 70.87 N +ANISOU 4194 N GLN B 155 12234 8370 6322 -1958 1675 -2054 N +ATOM 4195 CA GLN B 155 25.431 -18.356 44.965 1.00 72.66 C +ANISOU 4195 CA GLN B 155 12651 8308 6647 -1891 1991 -2244 C +ATOM 4196 C GLN B 155 25.404 -19.479 46.015 1.00 73.42 C +ANISOU 4196 C GLN B 155 12800 8070 7025 -1746 2184 -2216 C +ATOM 4197 O GLN B 155 25.926 -20.549 45.750 1.00 75.74 O +ANISOU 4197 O GLN B 155 13270 8091 7415 -1764 2456 -2398 O +ATOM 4198 CB GLN B 155 26.816 -17.736 44.677 1.00 71.53 C +ANISOU 4198 CB GLN B 155 12495 8210 6472 -1677 2065 -2241 C +ATOM 4199 CG GLN B 155 27.766 -17.516 45.831 1.00 69.65 C +ANISOU 4199 CG GLN B 155 12142 7857 6464 -1275 2121 -2054 C +ATOM 4200 CD GLN B 155 29.004 -16.738 45.379 1.00 68.78 C +ANISOU 4200 CD GLN B 155 11987 7852 6291 -1125 2150 -2054 C +ATOM 4201 OE1 GLN B 155 29.141 -16.383 44.196 1.00 68.33 O +ANISOU 4201 OE1 GLN B 155 12000 7945 6014 -1321 2146 -2195 O +ATOM 4202 NE2 GLN B 155 29.897 -16.446 46.329 1.00 68.01 N +ANISOU 4202 NE2 GLN B 155 11771 7689 6379 -789 2169 -1888 N +ATOM 4203 N ASN B 156 24.750 -19.271 47.157 1.00 72.56 N +ANISOU 4203 N ASN B 156 12552 7972 7043 -1622 2060 -1996 N +ATOM 4204 CA ASN B 156 24.575 -20.324 48.184 1.00 73.78 C +ANISOU 4204 CA ASN B 156 12762 7824 7446 -1511 2226 -1941 C +ATOM 4205 C ASN B 156 23.159 -20.902 48.214 1.00 75.57 C +ANISOU 4205 C ASN B 156 13007 8024 7680 -1796 2183 -1981 C +ATOM 4206 O ASN B 156 22.896 -21.827 48.983 1.00 76.15 O +ANISOU 4206 O ASN B 156 13141 7841 7948 -1751 2330 -1947 O +ATOM 4207 CB ASN B 156 24.910 -19.791 49.594 1.00 71.25 C +ANISOU 4207 CB ASN B 156 12294 7505 7273 -1159 2155 -1656 C +ATOM 4208 CG ASN B 156 26.396 -19.543 49.796 1.00 70.28 C +ANISOU 4208 CG ASN B 156 12159 7323 7219 -853 2243 -1608 C +ATOM 4209 OD1 ASN B 156 27.239 -20.229 49.237 1.00 72.13 O +ANISOU 4209 OD1 ASN B 156 12519 7375 7511 -833 2458 -1767 O +ATOM 4210 ND2 ASN B 156 26.720 -18.571 50.613 1.00 67.76 N +ANISOU 4210 ND2 ASN B 156 11684 7152 6908 -618 2087 -1391 N +ATOM 4211 N ASN B 157 22.262 -20.360 47.386 1.00 76.57 N +ANISOU 4211 N ASN B 157 13074 8415 7604 -2089 1978 -2040 N +ATOM 4212 CA ASN B 157 20.852 -20.792 47.319 1.00 78.70 C +ANISOU 4212 CA ASN B 157 13319 8709 7872 -2391 1895 -2072 C +ATOM 4213 C ASN B 157 20.067 -20.474 48.600 1.00 77.02 C +ANISOU 4213 C ASN B 157 12924 8520 7817 -2251 1793 -1814 C +ATOM 4214 O ASN B 157 19.263 -21.282 49.077 1.00 78.94 O +ANISOU 4214 O ASN B 157 13191 8604 8197 -2367 1872 -1814 O +ATOM 4215 CB ASN B 157 20.739 -22.288 46.975 1.00 82.49 C +ANISOU 4215 CB ASN B 157 14027 8877 8437 -2600 2152 -2313 C +ATOM 4216 CG ASN B 157 19.309 -22.710 46.644 1.00 85.21 C +ANISOU 4216 CG ASN B 157 14351 9280 8744 -2983 2051 -2391 C +ATOM 4217 OD1 ASN B 157 18.514 -21.903 46.152 1.00 85.62 O +ANISOU 4217 OD1 ASN B 157 14253 9647 8631 -3172 1779 -2340 O +ATOM 4218 ND2 ASN B 157 18.972 -23.982 46.922 1.00 87.33 N +ANISOU 4218 ND2 ASN B 157 14760 9238 9181 -3100 2267 -2503 N +ATOM 4219 N TRP B 158 20.301 -19.283 49.144 1.00 73.28 N +ANISOU 4219 N TRP B 158 12278 8242 7322 -2014 1631 -1602 N +ATOM 4220 CA TRP B 158 19.614 -18.830 50.336 1.00 71.35 C +ANISOU 4220 CA TRP B 158 11865 8042 7201 -1874 1543 -1365 C +ATOM 4221 C TRP B 158 18.275 -18.227 49.966 1.00 71.64 C +ANISOU 4221 C TRP B 158 11722 8329 7166 -2118 1315 -1315 C +ATOM 4222 O TRP B 158 18.135 -17.636 48.897 1.00 71.60 O +ANISOU 4222 O TRP B 158 11672 8551 6980 -2293 1148 -1381 O +ATOM 4223 CB TRP B 158 20.418 -17.730 51.037 1.00 68.31 C +ANISOU 4223 CB TRP B 158 11373 7768 6812 -1536 1464 -1176 C +ATOM 4224 CG TRP B 158 21.736 -18.140 51.643 1.00 67.24 C +ANISOU 4224 CG TRP B 158 11352 7420 6773 -1243 1643 -1154 C +ATOM 4225 CD1 TRP B 158 22.206 -19.413 51.859 1.00 68.83 C +ANISOU 4225 CD1 TRP B 158 11727 7310 7113 -1203 1884 -1239 C +ATOM 4226 CD2 TRP B 158 22.723 -17.257 52.165 1.00 64.82 C +ANISOU 4226 CD2 TRP B 158 10975 7195 6456 -948 1587 -1019 C +ATOM 4227 NE1 TRP B 158 23.437 -19.365 52.465 1.00 67.78 N +ANISOU 4227 NE1 TRP B 158 11621 7073 7058 -890 1967 -1150 N +ATOM 4228 CE2 TRP B 158 23.771 -18.053 52.677 1.00 65.51 C +ANISOU 4228 CE2 TRP B 158 11184 7031 6675 -738 1781 -1019 C +ATOM 4229 CE3 TRP B 158 22.830 -15.863 52.242 1.00 62.64 C +ANISOU 4229 CE3 TRP B 158 10541 7175 6082 -846 1391 -896 C +ATOM 4230 CZ2 TRP B 158 24.910 -17.497 53.267 1.00 63.96 C +ANISOU 4230 CZ2 TRP B 158 10943 6853 6506 -440 1765 -897 C +ATOM 4231 CZ3 TRP B 158 23.964 -15.312 52.820 1.00 61.22 C +ANISOU 4231 CZ3 TRP B 158 10335 7001 5922 -561 1390 -796 C +ATOM 4232 CH2 TRP B 158 24.989 -16.128 53.327 1.00 61.75 C +ANISOU 4232 CH2 TRP B 158 10513 6836 6113 -366 1566 -796 C +ATOM 4233 N GLN B 159 17.305 -18.348 50.877 1.00 71.69 N +ANISOU 4233 N GLN B 159 11617 8299 7322 -2121 1311 -1178 N +ATOM 4234 CA GLN B 159 16.040 -17.608 50.791 1.00 71.43 C +ANISOU 4234 CA GLN B 159 11352 8507 7282 -2277 1096 -1066 C +ATOM 4235 C GLN B 159 16.106 -16.379 51.685 1.00 68.14 C +ANISOU 4235 C GLN B 159 10757 8225 6905 -1995 998 -832 C +ATOM 4236 O GLN B 159 15.784 -16.431 52.869 1.00 67.67 O +ANISOU 4236 O GLN B 159 10649 8069 6994 -1846 1085 -692 O +ATOM 4237 CB GLN B 159 14.854 -18.497 51.174 1.00 74.08 C +ANISOU 4237 CB GLN B 159 11655 8720 7770 -2486 1168 -1074 C +ATOM 4238 CG GLN B 159 14.558 -19.588 50.147 1.00 77.55 C +ANISOU 4238 CG GLN B 159 12243 9069 8153 -2840 1221 -1321 C +ATOM 4239 CD GLN B 159 13.746 -20.737 50.710 1.00 80.08 C +ANISOU 4239 CD GLN B 159 12605 9158 8662 -2993 1385 -1352 C +ATOM 4240 OE1 GLN B 159 13.078 -20.611 51.741 1.00 79.30 O +ANISOU 4240 OE1 GLN B 159 12371 9034 8725 -2899 1410 -1174 O +ATOM 4241 NE2 GLN B 159 13.802 -21.872 50.031 1.00 83.43 N +ANISOU 4241 NE2 GLN B 159 13228 9402 9067 -3239 1517 -1588 N +ATOM 4242 N VAL B 160 16.534 -15.276 51.096 1.00 66.02 N +ANISOU 4242 N VAL B 160 10409 8176 6497 -1934 830 -796 N +ATOM 4243 CA VAL B 160 16.595 -14.007 51.773 1.00 63.52 C +ANISOU 4243 CA VAL B 160 9928 8000 6207 -1698 727 -597 C +ATOM 4244 C VAL B 160 15.384 -13.160 51.392 1.00 63.89 C +ANISOU 4244 C VAL B 160 9727 8285 6259 -1852 511 -488 C +ATOM 4245 O VAL B 160 15.118 -12.928 50.237 1.00 65.06 O +ANISOU 4245 O VAL B 160 9833 8604 6279 -2064 349 -547 O +ATOM 4246 CB VAL B 160 17.894 -13.265 51.406 1.00 61.63 C +ANISOU 4246 CB VAL B 160 9748 7834 5834 -1515 689 -611 C +ATOM 4247 CG1 VAL B 160 17.973 -11.911 52.104 1.00 59.57 C +ANISOU 4247 CG1 VAL B 160 9325 7707 5601 -1284 587 -418 C +ATOM 4248 CG2 VAL B 160 19.093 -14.128 51.772 1.00 61.30 C +ANISOU 4248 CG2 VAL B 160 9918 7554 5819 -1356 901 -704 C +ATOM 4249 N THR B 161 14.645 -12.698 52.383 1.00 63.58 N +ANISOU 4249 N THR B 161 9524 8258 6374 -1744 515 -320 N +ATOM 4250 CA THR B 161 13.595 -11.721 52.156 1.00 63.64 C +ANISOU 4250 CA THR B 161 9264 8483 6433 -1820 323 -179 C +ATOM 4251 C THR B 161 14.148 -10.357 52.566 1.00 61.07 C +ANISOU 4251 C THR B 161 8854 8257 6091 -1550 262 -39 C +ATOM 4252 O THR B 161 14.289 -10.071 53.740 1.00 59.25 O +ANISOU 4252 O THR B 161 8617 7935 5959 -1329 380 52 O +ATOM 4253 CB THR B 161 12.360 -12.066 52.998 1.00 65.05 C +ANISOU 4253 CB THR B 161 9297 8596 6821 -1879 399 -87 C +ATOM 4254 OG1 THR B 161 11.956 -13.412 52.726 1.00 67.19 O +ANISOU 4254 OG1 THR B 161 9674 8735 7118 -2122 488 -228 O +ATOM 4255 CG2 THR B 161 11.220 -11.121 52.710 1.00 65.81 C +ANISOU 4255 CG2 THR B 161 9087 8908 7009 -1965 208 63 C +ATOM 4256 N ALA B 162 14.493 -9.530 51.592 1.00 61.00 N +ANISOU 4256 N ALA B 162 8799 8430 5946 -1581 85 -30 N +ATOM 4257 CA ALA B 162 15.085 -8.229 51.856 1.00 59.31 C +ANISOU 4257 CA ALA B 162 8519 8302 5714 -1346 27 86 C +ATOM 4258 C ALA B 162 14.025 -7.138 51.902 1.00 60.36 C +ANISOU 4258 C ALA B 162 8373 8591 5970 -1345 -116 274 C +ATOM 4259 O ALA B 162 13.123 -7.125 51.067 1.00 62.71 O +ANISOU 4259 O ALA B 162 8526 9030 6272 -1566 -278 309 O +ATOM 4260 CB ALA B 162 16.101 -7.900 50.780 1.00 58.74 C +ANISOU 4260 CB ALA B 162 8555 8327 5435 -1370 -63 5 C +ATOM 4261 N ARG B 163 14.140 -6.225 52.867 1.00 59.22 N +ANISOU 4261 N ARG B 163 8152 8419 5928 -1102 -57 395 N +ATOM 4262 CA ARG B 163 13.290 -5.034 52.922 1.00 59.91 C +ANISOU 4262 CA ARG B 163 7978 8631 6153 -1056 -168 577 C +ATOM 4263 C ARG B 163 14.121 -3.818 53.266 1.00 58.77 C +ANISOU 4263 C ARG B 163 7844 8500 5983 -816 -166 644 C +ATOM 4264 O ARG B 163 14.866 -3.829 54.236 1.00 57.11 O +ANISOU 4264 O ARG B 163 7769 8163 5764 -630 -12 605 O +ATOM 4265 CB ARG B 163 12.185 -5.164 53.952 1.00 60.61 C +ANISOU 4265 CB ARG B 163 7917 8640 6470 -1027 -47 665 C +ATOM 4266 CG ARG B 163 11.132 -6.200 53.635 1.00 62.80 C +ANISOU 4266 CG ARG B 163 8117 8919 6825 -1281 -62 631 C +ATOM 4267 CD ARG B 163 10.096 -5.680 52.657 1.00 64.52 C +ANISOU 4267 CD ARG B 163 8062 9339 7112 -1461 -297 750 C +ATOM 4268 NE ARG B 163 9.013 -6.660 52.494 1.00 66.62 N +ANISOU 4268 NE ARG B 163 8227 9603 7479 -1711 -306 723 N +ATOM 4269 CZ ARG B 163 9.082 -7.751 51.732 1.00 67.25 C +ANISOU 4269 CZ ARG B 163 8445 9684 7422 -1962 -354 568 C +ATOM 4270 NH1 ARG B 163 10.178 -8.031 51.032 1.00 66.05 N +ANISOU 4270 NH1 ARG B 163 8536 9533 7025 -1992 -385 424 N +ATOM 4271 NH2 ARG B 163 8.047 -8.572 51.669 1.00 69.54 N +ANISOU 4271 NH2 ARG B 163 8626 9966 7829 -2192 -356 549 N +ATOM 4272 N SER B 164 13.945 -2.766 52.473 1.00 60.51 N +ANISOU 4272 N SER B 164 7915 8879 6196 -833 -345 757 N +ATOM 4273 CA SER B 164 14.665 -1.520 52.620 1.00 60.13 C +ANISOU 4273 CA SER B 164 7860 8853 6133 -638 -363 828 C +ATOM 4274 C SER B 164 13.872 -0.582 53.504 1.00 60.89 C +ANISOU 4274 C SER B 164 7759 8915 6461 -491 -302 979 C +ATOM 4275 O SER B 164 12.914 0.032 53.058 1.00 62.30 O +ANISOU 4275 O SER B 164 7703 9194 6774 -547 -423 1128 O +ATOM 4276 CB SER B 164 14.852 -0.853 51.263 1.00 61.29 C +ANISOU 4276 CB SER B 164 7952 9176 6158 -740 -578 889 C +ATOM 4277 OG SER B 164 15.356 0.463 51.428 1.00 60.70 O +ANISOU 4277 OG SER B 164 7832 9114 6116 -558 -594 988 O +ATOM 4278 N VAL B 165 14.318 -0.432 54.740 1.00 60.58 N +ANISOU 4278 N VAL B 165 7817 8736 6463 -301 -115 943 N +ATOM 4279 CA VAL B 165 13.552 0.264 55.767 1.00 61.76 C +ANISOU 4279 CA VAL B 165 7822 8817 6827 -170 7 1046 C +ATOM 4280 C VAL B 165 14.080 1.673 56.065 1.00 61.20 C +ANISOU 4280 C VAL B 165 7729 8735 6788 17 20 1108 C +ATOM 4281 O VAL B 165 13.666 2.313 57.022 1.00 60.75 O +ANISOU 4281 O VAL B 165 7603 8593 6885 147 161 1160 O +ATOM 4282 CB VAL B 165 13.531 -0.589 57.058 1.00 62.25 C +ANISOU 4282 CB VAL B 165 8021 8724 6906 -113 232 962 C +ATOM 4283 CG1 VAL B 165 12.895 -1.941 56.764 1.00 63.56 C +ANISOU 4283 CG1 VAL B 165 8192 8881 7077 -308 233 912 C +ATOM 4284 CG2 VAL B 165 14.937 -0.774 57.655 1.00 59.91 C +ANISOU 4284 CG2 VAL B 165 7990 8344 6429 15 314 847 C +ATOM 4285 N GLY B 166 14.977 2.163 55.225 1.00 62.71 N +ANISOU 4285 N GLY B 166 7982 9005 6838 18 -113 1098 N +ATOM 4286 CA GLY B 166 15.610 3.458 55.432 1.00 63.58 C +ANISOU 4286 CA GLY B 166 8094 9095 6965 176 -104 1143 C +ATOM 4287 C GLY B 166 14.683 4.659 55.458 1.00 65.73 C +ANISOU 4287 C GLY B 166 8127 9372 7472 245 -116 1315 C +ATOM 4288 O GLY B 166 14.972 5.632 56.146 1.00 66.45 O +ANISOU 4288 O GLY B 166 8229 9378 7641 401 -11 1329 O +ATOM 4289 N ASN B 167 13.570 4.588 54.731 1.00 68.38 N +ANISOU 4289 N ASN B 167 8244 9803 7934 128 -240 1446 N +ATOM 4290 CA ASN B 167 12.675 5.736 54.580 1.00 70.87 C +ANISOU 4290 CA ASN B 167 8296 10131 8500 195 -279 1645 C +ATOM 4291 C ASN B 167 11.484 5.736 55.547 1.00 72.72 C +ANISOU 4291 C ASN B 167 8355 10267 9008 256 -104 1702 C +ATOM 4292 O ASN B 167 10.765 6.724 55.662 1.00 74.35 O +ANISOU 4292 O ASN B 167 8343 10438 9466 353 -74 1856 O +ATOM 4293 CB ASN B 167 12.181 5.796 53.140 1.00 72.84 C +ANISOU 4293 CB ASN B 167 8381 10562 8733 34 -548 1792 C +ATOM 4294 CG ASN B 167 13.326 5.863 52.139 1.00 73.36 C +ANISOU 4294 CG ASN B 167 8621 10727 8524 -32 -699 1740 C +ATOM 4295 OD1 ASN B 167 14.381 6.456 52.413 1.00 71.98 O +ANISOU 4295 OD1 ASN B 167 8597 10486 8267 90 -627 1676 O +ATOM 4296 ND2 ASN B 167 13.129 5.247 50.974 1.00 75.32 N +ANISOU 4296 ND2 ASN B 167 8854 11137 8626 -243 -902 1760 N +ATOM 4297 N ILE B 168 11.289 4.637 56.261 1.00 72.55 N +ANISOU 4297 N ILE B 168 8430 10187 8948 204 29 1583 N +ATOM 4298 CA ILE B 168 10.146 4.518 57.155 1.00 73.87 C +ANISOU 4298 CA ILE B 168 8438 10265 9361 238 213 1631 C +ATOM 4299 C ILE B 168 10.289 5.522 58.298 1.00 74.36 C +ANISOU 4299 C ILE B 168 8535 10174 9544 448 447 1620 C +ATOM 4300 O ILE B 168 11.265 5.499 59.031 1.00 72.16 O +ANISOU 4300 O ILE B 168 8511 9815 9090 529 562 1479 O +ATOM 4301 CB ILE B 168 10.018 3.092 57.717 1.00 72.73 C +ANISOU 4301 CB ILE B 168 8430 10077 9126 134 325 1500 C +ATOM 4302 CG1 ILE B 168 9.834 2.075 56.591 1.00 73.32 C +ANISOU 4302 CG1 ILE B 168 8482 10285 9090 -94 113 1488 C +ATOM 4303 CG2 ILE B 168 8.843 3.017 58.663 1.00 74.32 C +ANISOU 4303 CG2 ILE B 168 8468 10183 9584 166 539 1553 C +ATOM 4304 CD1 ILE B 168 9.906 0.639 57.048 1.00 73.21 C +ANISOU 4304 CD1 ILE B 168 8644 10205 8966 -200 221 1345 C +ATOM 4305 N LYS B 169 9.327 6.428 58.419 1.00 78.14 N +ANISOU 4305 N LYS B 169 8752 10612 10324 531 512 1770 N +ATOM 4306 CA LYS B 169 9.238 7.322 59.572 1.00 79.99 C +ANISOU 4306 CA LYS B 169 9003 10678 10711 713 782 1748 C +ATOM 4307 C LYS B 169 8.062 6.911 60.496 1.00 84.16 C +ANISOU 4307 C LYS B 169 9397 11116 11463 717 1025 1761 C +ATOM 4308 O LYS B 169 7.894 7.459 61.589 1.00 85.10 O +ANISOU 4308 O LYS B 169 9556 11085 11691 845 1300 1714 O +ATOM 4309 CB LYS B 169 9.106 8.778 59.100 1.00 79.99 C +ANISOU 4309 CB LYS B 169 8821 10654 10915 832 730 1900 C +ATOM 4310 N ASP B 170 7.257 5.943 60.052 1.00 87.75 N +ANISOU 4310 N ASP B 170 9701 11661 11978 562 933 1816 N +ATOM 4311 CA ASP B 170 6.079 5.451 60.773 1.00 91.66 C +ANISOU 4311 CA ASP B 170 10034 12089 12700 533 1142 1845 C +ATOM 4312 C ASP B 170 6.374 4.105 61.459 1.00 91.63 C +ANISOU 4312 C ASP B 170 10286 12051 12476 434 1258 1683 C +ATOM 4313 O ASP B 170 6.456 3.061 60.803 1.00 90.65 O +ANISOU 4313 O ASP B 170 10202 12024 12216 265 1086 1654 O +ATOM 4314 CB ASP B 170 4.909 5.308 59.769 1.00 95.37 C +ANISOU 4314 CB ASP B 170 10126 12689 13418 409 944 2037 C +ATOM 4315 CG ASP B 170 3.570 4.928 60.429 1.00 99.25 C +ANISOU 4315 CG ASP B 170 10377 13118 14213 380 1157 2098 C +ATOM 4316 OD1 ASP B 170 3.502 4.827 61.682 1.00100.83 O +ANISOU 4316 OD1 ASP B 170 10709 13166 14435 463 1483 1994 O +ATOM 4317 OD2 ASP B 170 2.590 4.722 59.672 1.00101.13 O +ANISOU 4317 OD2 ASP B 170 10292 13469 14661 261 991 2253 O +ATOM 4318 N VAL B 171 6.503 4.130 62.786 1.00 92.72 N +ANISOU 4318 N VAL B 171 10601 12043 12583 532 1558 1582 N +ATOM 4319 CA VAL B 171 6.766 2.906 63.572 1.00 91.65 C +ANISOU 4319 CA VAL B 171 10717 11856 12249 457 1693 1454 C +ATOM 4320 C VAL B 171 5.702 1.816 63.395 1.00 92.96 C +ANISOU 4320 C VAL B 171 10713 12050 12555 288 1706 1505 C +ATOM 4321 O VAL B 171 5.995 0.633 63.557 1.00 91.42 O +ANISOU 4321 O VAL B 171 10708 11846 12182 178 1711 1420 O +ATOM 4322 CB VAL B 171 6.898 3.200 65.085 1.00 91.85 C +ANISOU 4322 CB VAL B 171 10938 11727 12232 581 2030 1364 C +ATOM 4323 CG1 VAL B 171 8.052 4.160 65.358 1.00 90.65 C +ANISOU 4323 CG1 VAL B 171 10995 11544 11901 719 2018 1284 C +ATOM 4324 CG2 VAL B 171 5.584 3.719 65.676 1.00 94.27 C +ANISOU 4324 CG2 VAL B 171 10989 11946 12883 632 2294 1448 C +ATOM 4325 N GLN B 172 4.473 2.210 63.075 1.00 95.39 N +ANISOU 4325 N GLN B 172 10658 12385 13198 266 1716 1649 N +ATOM 4326 CA GLN B 172 3.422 1.244 62.766 1.00 97.66 C +ANISOU 4326 CA GLN B 172 10737 12721 13646 81 1690 1709 C +ATOM 4327 C GLN B 172 3.811 0.365 61.559 1.00 96.00 C +ANISOU 4327 C GLN B 172 10574 12654 13247 -113 1364 1683 C +ATOM 4328 O GLN B 172 3.414 -0.801 61.486 1.00 97.19 O +ANISOU 4328 O GLN B 172 10734 12812 13382 -291 1364 1646 O +ATOM 4329 CB GLN B 172 2.094 1.986 62.516 1.00101.14 C +ANISOU 4329 CB GLN B 172 10734 13187 14506 106 1715 1893 C +ATOM 4330 CG GLN B 172 0.857 1.133 62.222 1.00104.56 C +ANISOU 4330 CG GLN B 172 10879 13677 15169 -87 1691 1979 C +ATOM 4331 CD GLN B 172 0.230 0.512 63.458 1.00106.40 C +ANISOU 4331 CD GLN B 172 11150 13767 15507 -101 2059 1924 C +ATOM 4332 OE1 GLN B 172 0.799 0.550 64.549 1.00105.85 O +ANISOU 4332 OE1 GLN B 172 11375 13564 15277 13 2319 1808 O +ATOM 4333 NE2 GLN B 172 -0.965 -0.059 63.293 1.00108.60 N +ANISOU 4333 NE2 GLN B 172 11126 14081 16054 -254 2080 2015 N +ATOM 4334 N GLU B 173 4.595 0.915 60.631 1.00 93.49 N +ANISOU 4334 N GLU B 173 10301 12437 12783 -87 1108 1694 N +ATOM 4335 CA GLU B 173 4.934 0.218 59.392 1.00 92.08 C +ANISOU 4335 CA GLU B 173 10157 12402 12426 -277 805 1670 C +ATOM 4336 C GLU B 173 5.957 -0.912 59.580 1.00 87.99 C +ANISOU 4336 C GLU B 173 10009 11832 11592 -343 831 1485 C +ATOM 4337 O GLU B 173 6.034 -1.814 58.749 1.00 87.38 O +ANISOU 4337 O GLU B 173 9972 11830 11396 -536 662 1433 O +ATOM 4338 CB GLU B 173 5.438 1.235 58.368 1.00 92.71 C +ANISOU 4338 CB GLU B 173 10171 12602 12452 -223 551 1752 C +ATOM 4339 CG GLU B 173 5.448 0.764 56.921 1.00 94.54 C +ANISOU 4339 CG GLU B 173 10342 13017 12561 -438 220 1779 C +ATOM 4340 CD GLU B 173 5.726 1.911 55.952 1.00 95.12 C +ANISOU 4340 CD GLU B 173 10301 13212 12628 -380 -14 1911 C +ATOM 4341 OE1 GLU B 173 6.561 1.738 55.036 1.00 94.59 O +ANISOU 4341 OE1 GLU B 173 10395 13246 12298 -467 -216 1853 O +ATOM 4342 OE2 GLU B 173 5.123 3.000 56.112 1.00 96.06 O +ANISOU 4342 OE2 GLU B 173 10172 13314 13012 -242 19 2077 O +ATOM 4343 N PHE B 174 6.748 -0.851 60.654 1.00 84.34 N +ANISOU 4343 N PHE B 174 9812 11238 10993 -188 1038 1389 N +ATOM 4344 CA PHE B 174 7.638 -1.957 61.021 1.00 81.62 C +ANISOU 4344 CA PHE B 174 9797 10819 10393 -226 1096 1243 C +ATOM 4345 C PHE B 174 6.819 -3.153 61.469 1.00 83.68 C +ANISOU 4345 C PHE B 174 10044 11006 10744 -371 1242 1227 C +ATOM 4346 O PHE B 174 7.210 -4.295 61.243 1.00 82.32 O +ANISOU 4346 O PHE B 174 10047 10803 10426 -493 1209 1135 O +ATOM 4347 CB PHE B 174 8.597 -1.571 62.157 1.00 79.56 C +ANISOU 4347 CB PHE B 174 9802 10448 9979 -30 1273 1172 C +ATOM 4348 CG PHE B 174 9.710 -0.645 61.743 1.00 76.48 C +ANISOU 4348 CG PHE B 174 9504 10112 9439 89 1130 1147 C +ATOM 4349 CD1 PHE B 174 10.663 -1.051 60.825 1.00 74.89 C +ANISOU 4349 CD1 PHE B 174 9434 9984 9037 28 927 1080 C +ATOM 4350 CD2 PHE B 174 9.820 0.624 62.295 1.00 75.75 C +ANISOU 4350 CD2 PHE B 174 9378 9987 9413 259 1221 1181 C +ATOM 4351 CE1 PHE B 174 11.694 -0.201 60.444 1.00 72.97 C +ANISOU 4351 CE1 PHE B 174 9267 9789 8666 131 809 1060 C +ATOM 4352 CE2 PHE B 174 10.848 1.476 61.921 1.00 74.28 C +ANISOU 4352 CE2 PHE B 174 9278 9844 9101 356 1096 1157 C +ATOM 4353 CZ PHE B 174 11.779 1.069 60.988 1.00 72.56 C +ANISOU 4353 CZ PHE B 174 9172 9708 8688 291 886 1103 C +ATOM 4354 N ARG B 175 5.693 -2.896 62.128 1.00 87.50 N +ANISOU 4354 N ARG B 175 10319 11443 11481 -356 1426 1313 N +ATOM 4355 CA ARG B 175 4.816 -3.974 62.571 1.00 91.09 C +ANISOU 4355 CA ARG B 175 10730 11824 12054 -504 1585 1311 C +ATOM 4356 C ARG B 175 4.234 -4.726 61.394 1.00 90.81 C +ANISOU 4356 C ARG B 175 10524 11896 12083 -753 1364 1323 C +ATOM 4357 O ARG B 175 4.198 -5.957 61.402 1.00 90.87 O +ANISOU 4357 O ARG B 175 10658 11841 12025 -912 1403 1246 O +ATOM 4358 CB ARG B 175 3.686 -3.446 63.448 1.00 95.84 C +ANISOU 4358 CB ARG B 175 11108 12365 12942 -438 1837 1408 C +ATOM 4359 CG ARG B 175 4.168 -2.875 64.772 1.00 97.55 C +ANISOU 4359 CG ARG B 175 11536 12456 13071 -230 2109 1369 C +ATOM 4360 CD ARG B 175 3.108 -2.969 65.867 1.00102.35 C +ANISOU 4360 CD ARG B 175 12040 12953 13893 -225 2448 1414 C +ATOM 4361 NE ARG B 175 2.305 -1.751 66.005 1.00105.84 N +ANISOU 4361 NE ARG B 175 12185 13402 14626 -111 2552 1512 N +ATOM 4362 CZ ARG B 175 2.488 -0.807 66.934 1.00107.46 C +ANISOU 4362 CZ ARG B 175 12478 13519 14832 73 2780 1491 C +ATOM 4363 NH1 ARG B 175 3.467 -0.898 67.831 1.00106.25 N +ANISOU 4363 NH1 ARG B 175 12703 13287 14379 159 2905 1380 N +ATOM 4364 NH2 ARG B 175 1.692 0.253 66.959 1.00110.46 N +ANISOU 4364 NH2 ARG B 175 12563 13887 15519 170 2882 1583 N +ATOM 4365 N ARG B 176 3.786 -3.990 60.382 1.00 90.31 N +ANISOU 4365 N ARG B 176 10182 11989 12143 -797 1130 1422 N +ATOM 4366 CA ARG B 176 3.206 -4.617 59.205 1.00 91.73 C +ANISOU 4366 CA ARG B 176 10190 12300 12363 -1057 887 1439 C +ATOM 4367 C ARG B 176 4.251 -5.521 58.527 1.00 89.00 C +ANISOU 4367 C ARG B 176 10150 11961 11702 -1175 748 1280 C +ATOM 4368 O ARG B 176 3.919 -6.603 58.049 1.00 90.95 O +ANISOU 4368 O ARG B 176 10412 12215 11929 -1412 690 1212 O +ATOM 4369 CB ARG B 176 2.657 -3.550 58.244 1.00 94.37 C +ANISOU 4369 CB ARG B 176 10187 12814 12853 -1061 635 1600 C +ATOM 4370 CG ARG B 176 1.725 -4.066 57.156 1.00 98.27 C +ANISOU 4370 CG ARG B 176 10417 13466 13452 -1345 388 1663 C +ATOM 4371 CD ARG B 176 1.804 -3.231 55.875 1.00 99.01 C +ANISOU 4371 CD ARG B 176 10348 13767 13502 -1379 42 1776 C +ATOM 4372 NE ARG B 176 1.714 -1.780 56.100 1.00 98.64 N +ANISOU 4372 NE ARG B 176 10119 13729 13629 -1130 61 1941 N +ATOM 4373 CZ ARG B 176 0.619 -1.126 56.503 1.00100.58 C +ANISOU 4373 CZ ARG B 176 10010 13964 14240 -1048 151 2116 C +ATOM 4374 NH1 ARG B 176 -0.520 -1.769 56.766 1.00102.21 N +ANISOU 4374 NH1 ARG B 176 9981 14164 14689 -1194 232 2159 N +ATOM 4375 NH2 ARG B 176 0.666 0.195 56.657 1.00100.50 N +ANISOU 4375 NH2 ARG B 176 9873 13938 14374 -815 177 2249 N +ATOM 4376 N ILE B 177 5.509 -5.085 58.513 1.00 85.34 N +ANISOU 4376 N ILE B 177 9930 11485 11011 -1015 715 1215 N +ATOM 4377 CA ILE B 177 6.605 -5.868 57.935 1.00 83.05 C +ANISOU 4377 CA ILE B 177 9931 11182 10439 -1089 620 1064 C +ATOM 4378 C ILE B 177 6.886 -7.148 58.729 1.00 82.58 C +ANISOU 4378 C ILE B 177 10126 10938 10310 -1124 836 949 C +ATOM 4379 O ILE B 177 7.046 -8.215 58.149 1.00 82.24 O +ANISOU 4379 O ILE B 177 10204 10871 10173 -1309 783 842 O +ATOM 4380 CB ILE B 177 7.895 -5.032 57.824 1.00 80.07 C +ANISOU 4380 CB ILE B 177 9726 10828 9866 -892 554 1035 C +ATOM 4381 CG1 ILE B 177 7.729 -3.949 56.760 1.00 80.46 C +ANISOU 4381 CG1 ILE B 177 9562 11063 9944 -904 303 1141 C +ATOM 4382 CG2 ILE B 177 9.088 -5.909 57.474 1.00 79.32 C +ANISOU 4382 CG2 ILE B 177 9943 10681 9511 -932 528 875 C +ATOM 4383 CD1 ILE B 177 8.842 -2.921 56.756 1.00 78.55 C +ANISOU 4383 CD1 ILE B 177 9440 10836 9566 -698 265 1141 C +ATOM 4384 N ILE B 178 6.948 -7.041 60.050 1.00 82.68 N +ANISOU 4384 N ILE B 178 10232 10816 10366 -952 1086 974 N +ATOM 4385 CA ILE B 178 7.192 -8.212 60.898 1.00 83.46 C +ANISOU 4385 CA ILE B 178 10575 10733 10403 -969 1298 902 C +ATOM 4386 C ILE B 178 6.045 -9.226 60.812 1.00 87.56 C +ANISOU 4386 C ILE B 178 10966 11206 11094 -1209 1366 904 C +ATOM 4387 O ILE B 178 6.292 -10.431 60.685 1.00 88.38 O +ANISOU 4387 O ILE B 178 11252 11204 11121 -1341 1407 808 O +ATOM 4388 CB ILE B 178 7.462 -7.805 62.360 1.00 81.72 C +ANISOU 4388 CB ILE B 178 10485 10398 10166 -746 1543 944 C +ATOM 4389 CG1 ILE B 178 8.813 -7.075 62.447 1.00 78.90 C +ANISOU 4389 CG1 ILE B 178 10316 10065 9596 -542 1469 907 C +ATOM 4390 CG2 ILE B 178 7.474 -9.035 63.264 1.00 82.31 C +ANISOU 4390 CG2 ILE B 178 10775 10292 10207 -786 1767 913 C +ATOM 4391 CD1 ILE B 178 8.998 -6.223 63.682 1.00 78.13 C +ANISOU 4391 CD1 ILE B 178 10281 9917 9484 -332 1645 955 C +ATOM 4392 N GLU B 179 4.804 -8.739 60.864 1.00 91.46 N +ANISOU 4392 N GLU B 179 11140 11771 11837 -1268 1384 1015 N +ATOM 4393 CA GLU B 179 3.616 -9.603 60.734 1.00 96.33 C +ANISOU 4393 CA GLU B 179 11580 12367 12653 -1514 1432 1030 C +ATOM 4394 C GLU B 179 3.619 -10.401 59.420 1.00 97.62 C +ANISOU 4394 C GLU B 179 11744 12608 12737 -1785 1196 932 C +ATOM 4395 O GLU B 179 3.242 -11.574 59.389 1.00 98.05 O +ANISOU 4395 O GLU B 179 11858 12565 12829 -1992 1270 860 O +ATOM 4396 CB GLU B 179 2.316 -8.782 60.860 1.00 99.99 C +ANISOU 4396 CB GLU B 179 11643 12924 13423 -1519 1452 1182 C +ATOM 4397 CG GLU B 179 1.931 -8.414 62.294 1.00101.80 C +ANISOU 4397 CG GLU B 179 11864 13026 13787 -1342 1782 1253 C +ATOM 4398 CD GLU B 179 0.764 -7.428 62.382 1.00105.31 C +ANISOU 4398 CD GLU B 179 11904 13556 14554 -1302 1816 1404 C +ATOM 4399 OE1 GLU B 179 -0.081 -7.413 61.457 1.00109.09 O +ANISOU 4399 OE1 GLU B 179 12064 14170 15214 -1479 1615 1472 O +ATOM 4400 OE2 GLU B 179 0.681 -6.666 63.379 1.00105.00 O +ANISOU 4400 OE2 GLU B 179 11859 13444 14590 -1096 2047 1456 O +ATOM 4401 N GLU B 180 4.058 -9.752 58.347 1.00 97.78 N +ANISOU 4401 N GLU B 180 11714 12796 12639 -1791 925 925 N +ATOM 4402 CA GLU B 180 4.204 -10.389 57.040 1.00 98.91 C +ANISOU 4402 CA GLU B 180 11898 13031 12650 -2044 693 816 C +ATOM 4403 C GLU B 180 5.236 -11.531 57.092 1.00 97.59 C +ANISOU 4403 C GLU B 180 12114 12692 12272 -2072 799 636 C +ATOM 4404 O GLU B 180 5.018 -12.603 56.516 1.00 99.05 O +ANISOU 4404 O GLU B 180 12366 12834 12432 -2329 771 520 O +ATOM 4405 CB GLU B 180 4.619 -9.327 56.013 1.00 98.70 C +ANISOU 4405 CB GLU B 180 11782 13213 12506 -1998 412 861 C +ATOM 4406 CG GLU B 180 4.381 -9.673 54.552 1.00101.36 C +ANISOU 4406 CG GLU B 180 12049 13719 12742 -2295 127 803 C +ATOM 4407 CD GLU B 180 4.646 -8.489 53.626 1.00102.00 C +ANISOU 4407 CD GLU B 180 12007 14016 12730 -2238 -142 899 C +ATOM 4408 OE1 GLU B 180 5.538 -7.650 53.917 1.00 98.16 O +ANISOU 4408 OE1 GLU B 180 11631 13512 12152 -1979 -107 926 O +ATOM 4409 OE2 GLU B 180 3.963 -8.399 52.583 1.00106.08 O +ANISOU 4409 OE2 GLU B 180 12319 14725 13259 -2468 -400 952 O +ATOM 4410 N MET B 181 6.340 -11.306 57.806 1.00 94.84 N +ANISOU 4410 N MET B 181 12008 12236 11790 -1812 927 617 N +ATOM 4411 CA MET B 181 7.427 -12.281 57.890 1.00 94.00 C +ANISOU 4411 CA MET B 181 12247 11961 11505 -1790 1025 476 C +ATOM 4412 C MET B 181 7.081 -13.452 58.796 1.00 95.13 C +ANISOU 4412 C MET B 181 12516 11881 11746 -1847 1280 456 C +ATOM 4413 O MET B 181 7.681 -14.513 58.687 1.00 94.85 O +ANISOU 4413 O MET B 181 12725 11691 11623 -1909 1357 339 O +ATOM 4414 CB MET B 181 8.711 -11.623 58.397 1.00 91.73 C +ANISOU 4414 CB MET B 181 12147 11645 11058 -1491 1060 486 C +ATOM 4415 CG MET B 181 9.214 -10.437 57.580 1.00 90.78 C +ANISOU 4415 CG MET B 181 11939 11721 10833 -1410 836 508 C +ATOM 4416 SD MET B 181 9.816 -10.804 55.913 1.00 90.38 S +ANISOU 4416 SD MET B 181 11975 11778 10587 -1611 607 359 S +ATOM 4417 CE MET B 181 8.364 -10.492 54.910 1.00 92.92 C +ANISOU 4417 CE MET B 181 11956 12314 11033 -1891 381 430 C +ATOM 4418 N ASP B 182 6.131 -13.258 59.704 1.00 97.25 N +ANISOU 4418 N ASP B 182 12623 12121 12205 -1821 1430 575 N +ATOM 4419 CA ASP B 182 5.593 -14.372 60.488 1.00 99.41 C +ANISOU 4419 CA ASP B 182 12978 12195 12596 -1922 1672 574 C +ATOM 4420 C ASP B 182 4.795 -15.338 59.625 1.00101.04 C +ANISOU 4420 C ASP B 182 13092 12397 12901 -2267 1605 484 C +ATOM 4421 O ASP B 182 4.848 -16.550 59.848 1.00102.05 O +ANISOU 4421 O ASP B 182 13408 12325 13041 -2383 1759 407 O +ATOM 4422 CB ASP B 182 4.716 -13.868 61.633 1.00101.16 C +ANISOU 4422 CB ASP B 182 13034 12400 12999 -1825 1866 721 C +ATOM 4423 CG ASP B 182 5.526 -13.360 62.806 1.00100.41 C +ANISOU 4423 CG ASP B 182 13138 12228 12785 -1523 2025 781 C +ATOM 4424 OD1 ASP B 182 6.773 -13.278 62.695 1.00 99.49 O +ANISOU 4424 OD1 ASP B 182 13247 12094 12459 -1377 1953 726 O +ATOM 4425 OD2 ASP B 182 4.909 -13.051 63.849 1.00101.99 O +ANISOU 4425 OD2 ASP B 182 13267 12385 13099 -1444 2229 882 O +ATOM 4426 N ARG B 183 4.070 -14.806 58.639 1.00100.47 N +ANISOU 4426 N ARG B 183 12736 12539 12898 -2436 1368 498 N +ATOM 4427 CA ARG B 183 3.327 -15.639 57.697 1.00101.71 C +ANISOU 4427 CA ARG B 183 12794 12731 13120 -2796 1253 403 C +ATOM 4428 C ARG B 183 4.252 -16.549 56.871 1.00101.36 C +ANISOU 4428 C ARG B 183 13051 12599 12862 -2922 1199 201 C +ATOM 4429 O ARG B 183 3.802 -17.568 56.356 1.00103.98 O +ANISOU 4429 O ARG B 183 13413 12862 13232 -3218 1201 82 O +ATOM 4430 CB ARG B 183 2.447 -14.779 56.784 1.00101.74 C +ANISOU 4430 CB ARG B 183 12428 13013 13215 -2936 971 486 C +ATOM 4431 N ARG B 184 5.534 -16.188 56.750 1.00 99.20 N +ANISOU 4431 N ARG B 184 12995 12317 12377 -2706 1166 155 N +ATOM 4432 CA ARG B 184 6.540 -17.050 56.107 1.00 99.08 C +ANISOU 4432 CA ARG B 184 13285 12181 12178 -2774 1174 -34 C +ATOM 4433 C ARG B 184 7.375 -17.881 57.101 1.00 96.14 C +ANISOU 4433 C ARG B 184 13218 11516 11792 -2591 1451 -57 C +ATOM 4434 O ARG B 184 8.310 -18.556 56.683 1.00 95.61 O +ANISOU 4434 O ARG B 184 13403 11321 11601 -2594 1490 -198 O +ATOM 4435 CB ARG B 184 7.494 -16.218 55.230 1.00 99.47 C +ANISOU 4435 CB ARG B 184 13383 12401 12009 -2670 967 -77 C +ATOM 4436 CG ARG B 184 6.830 -15.446 54.097 1.00102.59 C +ANISOU 4436 CG ARG B 184 13519 13087 12373 -2857 667 -50 C +ATOM 4437 CD ARG B 184 7.838 -14.693 53.228 1.00102.72 C +ANISOU 4437 CD ARG B 184 13620 13252 12157 -2763 488 -92 C +ATOM 4438 NE ARG B 184 7.190 -13.635 52.437 1.00104.84 N +ANISOU 4438 NE ARG B 184 13605 13809 12420 -2850 206 19 N +ATOM 4439 CZ ARG B 184 7.797 -12.859 51.533 1.00105.11 C +ANISOU 4439 CZ ARG B 184 13652 14021 12264 -2822 6 16 C +ATOM 4440 NH1 ARG B 184 9.090 -13.007 51.256 1.00104.57 N +ANISOU 4440 NH1 ARG B 184 13857 13880 11993 -2716 61 -110 N +ATOM 4441 NH2 ARG B 184 7.093 -11.936 50.885 1.00106.06 N +ANISOU 4441 NH2 ARG B 184 13498 14392 12408 -2904 -247 154 N +ATOM 4442 N GLN B 185 7.058 -17.828 58.398 1.00 93.52 N +ANISOU 4442 N GLN B 185 12866 11079 11586 -2431 1646 85 N +ATOM 4443 CA GLN B 185 7.759 -18.617 59.425 1.00 92.31 C +ANISOU 4443 CA GLN B 185 12993 10659 11422 -2264 1899 104 C +ATOM 4444 C GLN B 185 9.200 -18.134 59.718 1.00 87.56 C +ANISOU 4444 C GLN B 185 12585 10043 10639 -1949 1886 122 C +ATOM 4445 O GLN B 185 10.041 -18.904 60.181 1.00 86.41 O +ANISOU 4445 O GLN B 185 12694 9686 10452 -1834 2033 104 O +ATOM 4446 CB GLN B 185 7.735 -20.107 59.015 1.00 95.67 C +ANISOU 4446 CB GLN B 185 13601 10856 11890 -2499 2014 -46 C +ATOM 4447 CG GLN B 185 7.806 -21.169 60.122 1.00 97.38 C +ANISOU 4447 CG GLN B 185 14025 10769 12204 -2440 2307 11 C +ATOM 4448 CD GLN B 185 6.528 -21.327 60.939 1.00 99.31 C +ANISOU 4448 CD GLN B 185 14109 10979 12645 -2549 2455 131 C +ATOM 4449 OE1 GLN B 185 5.789 -20.363 61.152 1.00 98.52 O +ANISOU 4449 OE1 GLN B 185 13749 11077 12607 -2526 2382 235 O +ATOM 4450 NE2 GLN B 185 6.278 -22.546 61.419 1.00100.74 N +ANISOU 4450 NE2 GLN B 185 14444 10892 12940 -2662 2684 123 N +ATOM 4451 N GLU B 186 9.464 -16.853 59.483 1.00 83.79 N +ANISOU 4451 N GLU B 186 11974 9786 10076 -1809 1712 173 N +ATOM 4452 CA GLU B 186 10.819 -16.309 59.595 1.00 80.22 C +ANISOU 4452 CA GLU B 186 11671 9352 9455 -1546 1665 175 C +ATOM 4453 C GLU B 186 11.179 -16.051 61.055 1.00 77.87 C +ANISOU 4453 C GLU B 186 11470 8966 9151 -1282 1823 320 C +ATOM 4454 O GLU B 186 10.504 -15.291 61.746 1.00 78.23 O +ANISOU 4454 O GLU B 186 11366 9096 9261 -1220 1856 436 O +ATOM 4455 CB GLU B 186 10.943 -15.009 58.809 1.00 79.03 C +ANISOU 4455 CB GLU B 186 11346 9463 9220 -1508 1427 181 C +ATOM 4456 CG GLU B 186 10.612 -15.133 57.326 1.00 80.88 C +ANISOU 4456 CG GLU B 186 11488 9826 9415 -1774 1238 55 C +ATOM 4457 CD GLU B 186 11.778 -15.576 56.459 1.00 81.08 C +ANISOU 4457 CD GLU B 186 11726 9806 9273 -1784 1195 -103 C +ATOM 4458 OE1 GLU B 186 12.825 -15.980 57.006 1.00 80.29 O +ANISOU 4458 OE1 GLU B 186 11839 9541 9124 -1593 1328 -117 O +ATOM 4459 OE2 GLU B 186 11.640 -15.504 55.216 1.00 81.87 O +ANISOU 4459 OE2 GLU B 186 11773 10043 9290 -1987 1028 -207 O +ATOM 4460 N LYS B 187 12.250 -16.687 61.512 1.00 75.64 N +ANISOU 4460 N LYS B 187 11438 8512 8789 -1132 1923 314 N +ATOM 4461 CA LYS B 187 12.743 -16.515 62.875 1.00 73.69 C +ANISOU 4461 CA LYS B 187 11318 8187 8494 -890 2049 453 C +ATOM 4462 C LYS B 187 14.096 -15.792 62.969 1.00 69.70 C +ANISOU 4462 C LYS B 187 10900 7755 7825 -644 1941 467 C +ATOM 4463 O LYS B 187 14.506 -15.362 64.046 1.00 68.12 O +ANISOU 4463 O LYS B 187 10773 7553 7554 -449 1993 581 O +ATOM 4464 CB LYS B 187 12.871 -17.887 63.551 1.00 76.25 C +ANISOU 4464 CB LYS B 187 11859 8238 8872 -901 2259 488 C +ATOM 4465 CG LYS B 187 11.597 -18.723 63.575 1.00 78.77 C +ANISOU 4465 CG LYS B 187 12118 8449 9363 -1149 2398 478 C +ATOM 4466 CD LYS B 187 10.497 -18.079 64.408 1.00 79.13 C +ANISOU 4466 CD LYS B 187 11995 8585 9484 -1161 2477 600 C +ATOM 4467 CE LYS B 187 9.200 -18.869 64.305 1.00 81.56 C +ANISOU 4467 CE LYS B 187 12199 8803 9985 -1432 2601 583 C +ATOM 4468 NZ LYS B 187 9.341 -20.259 64.815 1.00 83.46 N +ANISOU 4468 NZ LYS B 187 12673 8758 10277 -1478 2811 602 N +ATOM 4469 N ARG B 188 14.795 -15.663 61.845 1.00 67.63 N +ANISOU 4469 N ARG B 188 10635 7561 7498 -666 1795 347 N +ATOM 4470 CA ARG B 188 16.144 -15.090 61.830 1.00 64.79 C +ANISOU 4470 CA ARG B 188 10353 7257 7004 -451 1702 347 C +ATOM 4471 C ARG B 188 16.176 -13.763 61.068 1.00 61.87 C +ANISOU 4471 C ARG B 188 9808 7131 6568 -447 1505 314 C +ATOM 4472 O ARG B 188 15.690 -13.659 59.947 1.00 61.61 O +ANISOU 4472 O ARG B 188 9659 7198 6553 -630 1400 223 O +ATOM 4473 CB ARG B 188 17.122 -16.098 61.244 1.00 65.40 C +ANISOU 4473 CB ARG B 188 10602 7178 7070 -446 1737 246 C +ATOM 4474 CG ARG B 188 17.072 -17.441 61.951 1.00 67.98 C +ANISOU 4474 CG ARG B 188 11103 7237 7489 -449 1939 293 C +ATOM 4475 CD ARG B 188 17.951 -18.482 61.308 1.00 69.04 C +ANISOU 4475 CD ARG B 188 11393 7185 7652 -452 2003 184 C +ATOM 4476 NE ARG B 188 17.488 -19.837 61.553 1.00 71.92 N +ANISOU 4476 NE ARG B 188 11886 7290 8150 -567 2195 179 N +ATOM 4477 CZ ARG B 188 18.211 -20.936 61.320 1.00 74.93 C +ANISOU 4477 CZ ARG B 188 12437 7430 8601 -539 2318 121 C +ATOM 4478 NH1 ARG B 188 19.445 -20.855 60.826 1.00 75.48 N +ANISOU 4478 NH1 ARG B 188 12559 7494 8625 -396 2272 61 N +ATOM 4479 NH2 ARG B 188 17.709 -22.138 61.568 1.00 77.32 N +ANISOU 4479 NH2 ARG B 188 12855 7482 9039 -655 2504 122 N +ATOM 4480 N TYR B 189 16.745 -12.748 61.700 1.00 59.36 N +ANISOU 4480 N TYR B 189 9477 6908 6169 -248 1454 393 N +ATOM 4481 CA TYR B 189 16.707 -11.390 61.188 1.00 57.61 C +ANISOU 4481 CA TYR B 189 9087 6895 5904 -224 1293 392 C +ATOM 4482 C TYR B 189 18.093 -10.785 61.205 1.00 55.91 C +ANISOU 4482 C TYR B 189 8948 6730 5564 -34 1209 385 C +ATOM 4483 O TYR B 189 18.705 -10.693 62.271 1.00 55.07 O +ANISOU 4483 O TYR B 189 8947 6571 5404 137 1266 461 O +ATOM 4484 CB TYR B 189 15.836 -10.531 62.082 1.00 57.43 C +ANISOU 4484 CB TYR B 189 8943 6938 5937 -177 1340 502 C +ATOM 4485 CG TYR B 189 14.361 -10.688 61.880 1.00 58.97 C +ANISOU 4485 CG TYR B 189 8968 7154 6284 -365 1380 521 C +ATOM 4486 CD1 TYR B 189 13.660 -11.724 62.478 1.00 60.71 C +ANISOU 4486 CD1 TYR B 189 9245 7225 6597 -457 1552 547 C +ATOM 4487 CD2 TYR B 189 13.656 -9.773 61.123 1.00 58.81 C +ANISOU 4487 CD2 TYR B 189 8714 7300 6328 -449 1246 531 C +ATOM 4488 CE1 TYR B 189 12.295 -11.855 62.305 1.00 62.45 C +ANISOU 4488 CE1 TYR B 189 9283 7467 6976 -639 1589 568 C +ATOM 4489 CE2 TYR B 189 12.300 -9.884 60.955 1.00 60.67 C +ANISOU 4489 CE2 TYR B 189 8759 7565 6725 -617 1269 566 C +ATOM 4490 CZ TYR B 189 11.625 -10.928 61.535 1.00 62.46 C +ANISOU 4490 CZ TYR B 189 9034 7649 7047 -717 1440 577 C +ATOM 4491 OH TYR B 189 10.274 -11.019 61.334 1.00 65.37 O +ANISOU 4491 OH TYR B 189 9186 8056 7593 -895 1456 613 O +ATOM 4492 N LEU B 190 18.582 -10.377 60.032 1.00 54.94 N +ANISOU 4492 N LEU B 190 8771 6715 5387 -78 1072 299 N +ATOM 4493 CA LEU B 190 19.783 -9.559 59.937 1.00 53.33 C +ANISOU 4493 CA LEU B 190 8586 6593 5081 80 977 295 C +ATOM 4494 C LEU B 190 19.347 -8.115 59.781 1.00 51.88 C +ANISOU 4494 C LEU B 190 8231 6587 4893 92 863 343 C +ATOM 4495 O LEU B 190 18.590 -7.805 58.874 1.00 51.49 O +ANISOU 4495 O LEU B 190 8044 6639 4879 -55 778 324 O +ATOM 4496 CB LEU B 190 20.606 -9.976 58.726 1.00 53.73 C +ANISOU 4496 CB LEU B 190 8689 6645 5078 22 924 171 C +ATOM 4497 CG LEU B 190 21.894 -9.197 58.460 1.00 52.42 C +ANISOU 4497 CG LEU B 190 8531 6564 4823 165 834 156 C +ATOM 4498 CD1 LEU B 190 22.862 -9.344 59.630 1.00 52.26 C +ANISOU 4498 CD1 LEU B 190 8617 6452 4788 379 893 228 C +ATOM 4499 CD2 LEU B 190 22.522 -9.694 57.178 1.00 53.20 C +ANISOU 4499 CD2 LEU B 190 8678 6657 4878 72 818 21 C +ATOM 4500 N ILE B 191 19.815 -7.250 60.669 1.00 51.28 N +ANISOU 4500 N ILE B 191 8164 6543 4774 260 862 410 N +ATOM 4501 CA ILE B 191 19.411 -5.847 60.688 1.00 51.21 C +ANISOU 4501 CA ILE B 191 8007 6665 4784 292 789 461 C +ATOM 4502 C ILE B 191 20.621 -4.956 60.478 1.00 51.07 C +ANISOU 4502 C ILE B 191 8007 6726 4671 412 687 441 C +ATOM 4503 O ILE B 191 21.433 -4.783 61.364 1.00 51.02 O +ANISOU 4503 O ILE B 191 8100 6685 4599 552 715 460 O +ATOM 4504 CB ILE B 191 18.699 -5.479 62.012 1.00 50.86 C +ANISOU 4504 CB ILE B 191 7954 6580 4790 360 911 546 C +ATOM 4505 CG1 ILE B 191 17.365 -6.206 62.091 1.00 52.34 C +ANISOU 4505 CG1 ILE B 191 8074 6709 5102 221 1012 572 C +ATOM 4506 CG2 ILE B 191 18.417 -3.995 62.087 1.00 49.97 C +ANISOU 4506 CG2 ILE B 191 7703 6570 4710 416 863 587 C +ATOM 4507 CD1 ILE B 191 16.747 -6.172 63.463 1.00 53.63 C +ANISOU 4507 CD1 ILE B 191 8275 6798 5302 280 1183 646 C +ATOM 4508 N ASP B 192 20.696 -4.368 59.298 1.00 53.32 N +ANISOU 4508 N ASP B 192 8189 7122 4945 341 563 410 N +ATOM 4509 CA ASP B 192 21.828 -3.559 58.831 1.00 54.01 C +ANISOU 4509 CA ASP B 192 8280 7290 4951 420 465 383 C +ATOM 4510 C ASP B 192 21.333 -2.128 58.777 1.00 53.46 C +ANISOU 4510 C ASP B 192 8063 7320 4927 439 399 452 C +ATOM 4511 O ASP B 192 21.084 -1.602 57.691 1.00 53.70 O +ANISOU 4511 O ASP B 192 7985 7451 4966 352 292 462 O +ATOM 4512 CB ASP B 192 22.232 -4.099 57.430 1.00 56.45 C +ANISOU 4512 CB ASP B 192 8604 7637 5206 300 399 296 C +ATOM 4513 CG ASP B 192 23.301 -3.249 56.677 1.00 57.43 C +ANISOU 4513 CG ASP B 192 8711 7860 5250 343 301 267 C +ATOM 4514 OD1 ASP B 192 24.184 -2.613 57.297 1.00 60.06 O +ANISOU 4514 OD1 ASP B 192 9067 8193 5558 488 297 286 O +ATOM 4515 OD2 ASP B 192 23.262 -3.271 55.418 1.00 58.09 O +ANISOU 4515 OD2 ASP B 192 8764 8022 5285 212 231 222 O +ATOM 4516 N CYS B 193 21.142 -1.511 59.942 1.00 52.96 N +ANISOU 4516 N CYS B 193 8003 7222 4896 546 471 503 N +ATOM 4517 CA CYS B 193 20.589 -0.140 60.010 1.00 52.52 C +ANISOU 4517 CA CYS B 193 7809 7223 4919 576 448 566 C +ATOM 4518 C CYS B 193 21.439 0.724 60.901 1.00 51.38 C +ANISOU 4518 C CYS B 193 7741 7064 4717 714 472 556 C +ATOM 4519 O CYS B 193 22.367 0.223 61.536 1.00 49.89 O +ANISOU 4519 O CYS B 193 7697 6834 4424 782 495 515 O +ATOM 4520 CB CYS B 193 19.172 -0.152 60.566 1.00 53.59 C +ANISOU 4520 CB CYS B 193 7848 7320 5193 541 551 631 C +ATOM 4521 SG CYS B 193 17.988 -0.997 59.517 1.00 54.45 S +ANISOU 4521 SG CYS B 193 7822 7466 5398 349 500 656 S +ATOM 4522 N GLU B 194 21.117 2.016 60.942 1.00 51.65 N +ANISOU 4522 N GLU B 194 7671 7127 4824 750 465 597 N +ATOM 4523 CA GLU B 194 21.674 2.912 61.953 1.00 53.26 C +ANISOU 4523 CA GLU B 194 7948 7299 4988 858 519 576 C +ATOM 4524 C GLU B 194 21.166 2.502 63.333 1.00 53.32 C +ANISOU 4524 C GLU B 194 8055 7221 4983 894 679 575 C +ATOM 4525 O GLU B 194 20.097 1.902 63.435 1.00 53.20 O +ANISOU 4525 O GLU B 194 7989 7169 5054 840 763 614 O +ATOM 4526 CB GLU B 194 21.280 4.368 61.708 1.00 55.67 C +ANISOU 4526 CB GLU B 194 8120 7620 5408 882 512 619 C +ATOM 4527 CG GLU B 194 21.929 5.016 60.495 1.00 58.36 C +ANISOU 4527 CG GLU B 194 8389 8043 5741 860 363 631 C +ATOM 4528 CD GLU B 194 23.450 5.149 60.594 1.00 59.93 C +ANISOU 4528 CD GLU B 194 8708 8264 5799 906 303 555 C +ATOM 4529 OE1 GLU B 194 23.958 5.610 61.648 1.00 61.64 O +ANISOU 4529 OE1 GLU B 194 9016 8436 5966 977 361 510 O +ATOM 4530 OE2 GLU B 194 24.132 4.804 59.600 1.00 60.22 O +ANISOU 4530 OE2 GLU B 194 8740 8364 5774 862 201 538 O +ATOM 4531 N VAL B 195 21.920 2.868 64.373 1.00 52.37 N +ANISOU 4531 N VAL B 195 8072 7076 4749 971 718 534 N +ATOM 4532 CA VAL B 195 21.574 2.546 65.762 1.00 54.07 C +ANISOU 4532 CA VAL B 195 8419 7221 4901 998 870 532 C +ATOM 4533 C VAL B 195 20.149 2.960 66.138 1.00 54.72 C +ANISOU 4533 C VAL B 195 8407 7248 5134 978 1036 567 C +ATOM 4534 O VAL B 195 19.393 2.155 66.652 1.00 54.21 O +ANISOU 4534 O VAL B 195 8374 7131 5089 946 1157 596 O +ATOM 4535 CB VAL B 195 22.585 3.168 66.766 1.00 54.32 C +ANISOU 4535 CB VAL B 195 8604 7259 4775 1063 864 477 C +ATOM 4536 CG1 VAL B 195 22.064 3.129 68.200 1.00 56.02 C +ANISOU 4536 CG1 VAL B 195 8959 7412 4914 1072 1040 472 C +ATOM 4537 CG2 VAL B 195 23.910 2.430 66.699 1.00 53.98 C +ANISOU 4537 CG2 VAL B 195 8660 7257 4591 1091 728 467 C +ATOM 4538 N GLU B 196 19.782 4.205 65.859 1.00 56.06 N +ANISOU 4538 N GLU B 196 8451 7419 5428 998 1053 571 N +ATOM 4539 CA GLU B 196 18.480 4.722 66.277 1.00 58.32 C +ANISOU 4539 CA GLU B 196 8629 7637 5889 1001 1233 607 C +ATOM 4540 C GLU B 196 17.347 3.952 65.635 1.00 57.10 C +ANISOU 4540 C GLU B 196 8310 7489 5893 928 1242 687 C +ATOM 4541 O GLU B 196 16.293 3.780 66.232 1.00 58.49 O +ANISOU 4541 O GLU B 196 8438 7603 6179 914 1418 718 O +ATOM 4542 CB GLU B 196 18.321 6.211 65.952 1.00 61.03 C +ANISOU 4542 CB GLU B 196 8845 7964 6378 1047 1242 614 C +ATOM 4543 CG GLU B 196 19.333 7.124 66.636 1.00 63.73 C +ANISOU 4543 CG GLU B 196 9341 8283 6587 1100 1255 519 C +ATOM 4544 CD GLU B 196 20.520 7.465 65.733 1.00 65.52 C +ANISOU 4544 CD GLU B 196 9562 8590 6742 1101 1041 505 C +ATOM 4545 OE1 GLU B 196 21.152 6.524 65.158 1.00 66.34 O +ANISOU 4545 OE1 GLU B 196 9694 8769 6741 1069 895 513 O +ATOM 4546 OE2 GLU B 196 20.802 8.688 65.581 1.00 67.50 O +ANISOU 4546 OE2 GLU B 196 9774 8815 7057 1131 1037 484 O +ATOM 4547 N ARG B 197 17.560 3.491 64.411 1.00 55.37 N +ANISOU 4547 N ARG B 197 8005 7348 5683 867 1059 716 N +ATOM 4548 CA ARG B 197 16.563 2.679 63.731 1.00 54.41 C +ANISOU 4548 CA ARG B 197 7740 7248 5685 765 1038 779 C +ATOM 4549 C ARG B 197 16.549 1.236 64.262 1.00 52.13 C +ANISOU 4549 C ARG B 197 7595 6912 5300 713 1109 752 C +ATOM 4550 O ARG B 197 15.494 0.615 64.353 1.00 52.78 O +ANISOU 4550 O ARG B 197 7593 6961 5498 640 1200 794 O +ATOM 4551 CB ARG B 197 16.775 2.725 62.225 1.00 54.93 C +ANISOU 4551 CB ARG B 197 7684 7419 5768 695 822 810 C +ATOM 4552 CG ARG B 197 15.678 2.023 61.458 1.00 56.92 C +ANISOU 4552 CG ARG B 197 7770 7710 6147 564 776 874 C +ATOM 4553 CD ARG B 197 15.679 2.420 59.995 1.00 57.83 C +ANISOU 4553 CD ARG B 197 7737 7944 6291 490 566 928 C +ATOM 4554 NE ARG B 197 15.109 3.763 59.808 1.00 59.20 N +ANISOU 4554 NE ARG B 197 7717 8134 6642 551 554 1034 N +ATOM 4555 CZ ARG B 197 15.803 4.852 59.484 1.00 58.85 C +ANISOU 4555 CZ ARG B 197 7674 8111 6573 627 483 1048 C +ATOM 4556 NH1 ARG B 197 17.126 4.796 59.282 1.00 58.30 N +ANISOU 4556 NH1 ARG B 197 7778 8067 6305 646 409 960 N +ATOM 4557 NH2 ARG B 197 15.173 6.008 59.347 1.00 59.40 N +ANISOU 4557 NH2 ARG B 197 7561 8168 6837 686 493 1159 N +ATOM 4558 N ILE B 198 17.704 0.707 64.636 1.00 49.04 N +ANISOU 4558 N ILE B 198 7409 6509 4712 753 1073 693 N +ATOM 4559 CA ILE B 198 17.724 -0.582 65.308 1.00 48.45 C +ANISOU 4559 CA ILE B 198 7488 6364 4554 727 1162 688 C +ATOM 4560 C ILE B 198 16.877 -0.538 66.597 1.00 49.38 C +ANISOU 4560 C ILE B 198 7654 6402 4705 745 1387 715 C +ATOM 4561 O ILE B 198 16.041 -1.422 66.808 1.00 49.62 O +ANISOU 4561 O ILE B 198 7669 6376 4806 673 1496 751 O +ATOM 4562 CB ILE B 198 19.152 -1.099 65.561 1.00 47.13 C +ANISOU 4562 CB ILE B 198 7520 6194 4191 789 1081 646 C +ATOM 4563 CG1 ILE B 198 19.828 -1.443 64.214 1.00 45.77 C +ANISOU 4563 CG1 ILE B 198 7299 6081 4010 747 907 613 C +ATOM 4564 CG2 ILE B 198 19.110 -2.346 66.445 1.00 47.79 C +ANISOU 4564 CG2 ILE B 198 7770 6185 4200 782 1195 671 C +ATOM 4565 CD1 ILE B 198 21.319 -1.683 64.283 1.00 44.64 C +ANISOU 4565 CD1 ILE B 198 7294 5947 3720 825 817 574 C +ATOM 4566 N ASN B 199 17.052 0.503 67.421 1.00 49.41 N +ANISOU 4566 N ASN B 199 7712 6396 4664 827 1470 691 N +ATOM 4567 CA ASN B 199 16.263 0.670 68.656 1.00 50.78 C +ANISOU 4567 CA ASN B 199 7945 6493 4854 840 1713 700 C +ATOM 4568 C ASN B 199 14.768 0.778 68.370 1.00 52.42 C +ANISOU 4568 C ASN B 199 7923 6670 5323 783 1839 756 C +ATOM 4569 O ASN B 199 13.959 0.130 69.018 1.00 53.94 O +ANISOU 4569 O ASN B 199 8136 6798 5560 737 2020 787 O +ATOM 4570 CB ASN B 199 16.728 1.883 69.467 1.00 50.50 C +ANISOU 4570 CB ASN B 199 8008 6451 4727 920 1780 639 C +ATOM 4571 CG ASN B 199 18.163 1.750 69.947 1.00 49.51 C +ANISOU 4571 CG ASN B 199 8109 6364 4339 963 1662 593 C +ATOM 4572 OD1 ASN B 199 18.617 0.661 70.283 1.00 50.51 O +ANISOU 4572 OD1 ASN B 199 8379 6483 4328 952 1630 621 O +ATOM 4573 ND2 ASN B 199 18.882 2.851 69.982 1.00 48.47 N +ANISOU 4573 ND2 ASN B 199 7998 6265 4149 1011 1594 531 N +ATOM 4574 N THR B 200 14.403 1.583 67.388 1.00 53.04 N +ANISOU 4574 N THR B 200 7772 6798 5580 783 1740 784 N +ATOM 4575 CA THR B 200 13.018 1.672 66.944 1.00 55.04 C +ANISOU 4575 CA THR B 200 7762 7045 6106 726 1809 862 C +ATOM 4576 C THR B 200 12.489 0.268 66.603 1.00 56.05 C +ANISOU 4576 C THR B 200 7858 7172 6263 599 1790 895 C +ATOM 4577 O THR B 200 11.470 -0.179 67.149 1.00 58.13 O +ANISOU 4577 O THR B 200 8062 7375 6650 549 1977 933 O +ATOM 4578 CB THR B 200 12.890 2.614 65.710 1.00 55.16 C +ANISOU 4578 CB THR B 200 7539 7138 6280 735 1628 915 C +ATOM 4579 OG1 THR B 200 13.414 3.907 66.028 1.00 55.19 O +ANISOU 4579 OG1 THR B 200 7583 7119 6267 848 1658 880 O +ATOM 4580 CG2 THR B 200 11.457 2.791 65.288 1.00 57.01 C +ANISOU 4580 CG2 THR B 200 7472 7374 6813 686 1681 1021 C +ATOM 4581 N ILE B 201 13.198 -0.435 65.721 1.00 54.65 N +ANISOU 4581 N ILE B 201 7733 7054 5977 541 1585 873 N +ATOM 4582 CA ILE B 201 12.750 -1.743 65.260 1.00 55.21 C +ANISOU 4582 CA ILE B 201 7781 7115 6081 404 1558 885 C +ATOM 4583 C ILE B 201 12.574 -2.686 66.444 1.00 56.09 C +ANISOU 4583 C ILE B 201 8073 7112 6123 394 1767 882 C +ATOM 4584 O ILE B 201 11.560 -3.377 66.553 1.00 57.48 O +ANISOU 4584 O ILE B 201 8162 7242 6435 291 1881 921 O +ATOM 4585 CB ILE B 201 13.728 -2.333 64.214 1.00 54.14 C +ANISOU 4585 CB ILE B 201 7724 7037 5809 355 1337 834 C +ATOM 4586 CG1 ILE B 201 13.543 -1.616 62.872 1.00 54.11 C +ANISOU 4586 CG1 ILE B 201 7506 7155 5896 305 1137 862 C +ATOM 4587 CG2 ILE B 201 13.503 -3.824 64.014 1.00 54.93 C +ANISOU 4587 CG2 ILE B 201 7891 7080 5897 224 1357 815 C +ATOM 4588 CD1 ILE B 201 14.669 -1.799 61.869 1.00 52.88 C +ANISOU 4588 CD1 ILE B 201 7439 7069 5584 285 938 800 C +ATOM 4589 N LEU B 202 13.556 -2.694 67.336 1.00 55.31 N +ANISOU 4589 N LEU B 202 8224 6975 5815 494 1813 846 N +ATOM 4590 CA LEU B 202 13.517 -3.580 68.493 1.00 56.12 C +ANISOU 4590 CA LEU B 202 8532 6977 5814 491 1996 863 C +ATOM 4591 C LEU B 202 12.391 -3.241 69.465 1.00 57.85 C +ANISOU 4591 C LEU B 202 8699 7136 6142 484 2260 899 C +ATOM 4592 O LEU B 202 11.815 -4.147 70.056 1.00 58.96 O +ANISOU 4592 O LEU B 202 8906 7195 6300 417 2425 937 O +ATOM 4593 CB LEU B 202 14.870 -3.607 69.212 1.00 55.03 C +ANISOU 4593 CB LEU B 202 8661 6832 5413 597 1950 836 C +ATOM 4594 CG LEU B 202 16.010 -4.303 68.450 1.00 53.72 C +ANISOU 4594 CG LEU B 202 8578 6687 5145 605 1745 812 C +ATOM 4595 CD1 LEU B 202 17.288 -4.234 69.261 1.00 53.47 C +ANISOU 4595 CD1 LEU B 202 8773 6659 4883 718 1700 808 C +ATOM 4596 CD2 LEU B 202 15.706 -5.750 68.114 1.00 54.19 C +ANISOU 4596 CD2 LEU B 202 8667 6664 5258 504 1770 835 C +ATOM 4597 N GLU B 203 12.072 -1.958 69.633 1.00 58.22 N +ANISOU 4597 N GLU B 203 8633 7211 6277 552 2322 887 N +ATOM 4598 CA GLU B 203 10.918 -1.587 70.464 1.00 60.31 C +ANISOU 4598 CA GLU B 203 8816 7409 6689 547 2602 913 C +ATOM 4599 C GLU B 203 9.627 -2.185 69.900 1.00 62.07 C +ANISOU 4599 C GLU B 203 8782 7618 7182 425 2654 981 C +ATOM 4600 O GLU B 203 8.767 -2.616 70.657 1.00 64.04 O +ANISOU 4600 O GLU B 203 9029 7789 7512 375 2898 1014 O +ATOM 4601 CB GLU B 203 10.758 -0.081 70.583 1.00 60.10 C +ANISOU 4601 CB GLU B 203 8679 7394 6760 643 2663 885 C +ATOM 4602 N GLN B 204 9.500 -2.223 68.577 1.00 62.11 N +ANISOU 4602 N GLN B 204 8577 7704 7317 363 2425 1003 N +ATOM 4603 CA GLN B 204 8.301 -2.795 67.938 1.00 63.75 C +ANISOU 4603 CA GLN B 204 8525 7922 7775 221 2428 1067 C +ATOM 4604 C GLN B 204 8.215 -4.294 68.113 1.00 65.04 C +ANISOU 4604 C GLN B 204 8822 8018 7872 94 2478 1063 C +ATOM 4605 O GLN B 204 7.130 -4.849 68.258 1.00 66.67 O +ANISOU 4605 O GLN B 204 8890 8179 8261 -17 2619 1110 O +ATOM 4606 CB GLN B 204 8.246 -2.461 66.449 1.00 62.73 C +ANISOU 4606 CB GLN B 204 8160 7915 7756 165 2142 1093 C +ATOM 4607 CG GLN B 204 8.171 -0.973 66.147 1.00 62.37 C +ANISOU 4607 CG GLN B 204 7938 7927 7832 281 2088 1129 C +ATOM 4608 CD GLN B 204 7.100 -0.249 66.940 1.00 63.88 C +ANISOU 4608 CD GLN B 204 7961 8048 8263 343 2354 1184 C +ATOM 4609 OE1 GLN B 204 5.968 -0.718 67.059 1.00 65.78 O +ANISOU 4609 OE1 GLN B 204 8017 8260 8714 252 2482 1244 O +ATOM 4610 NE2 GLN B 204 7.454 0.908 67.478 1.00 63.38 N +ANISOU 4610 NE2 GLN B 204 7953 7947 8181 493 2451 1156 N +ATOM 4611 N VAL B 205 9.365 -4.946 68.105 1.00 64.89 N +ANISOU 4611 N VAL B 205 9062 7982 7611 114 2371 1013 N +ATOM 4612 CA VAL B 205 9.444 -6.380 68.367 1.00 67.04 C +ANISOU 4612 CA VAL B 205 9505 8157 7808 19 2435 1014 C +ATOM 4613 C VAL B 205 8.853 -6.691 69.748 1.00 70.34 C +ANISOU 4613 C VAL B 205 10037 8464 8224 25 2745 1061 C +ATOM 4614 O VAL B 205 8.065 -7.628 69.909 1.00 72.62 O +ANISOU 4614 O VAL B 205 10294 8672 8624 -102 2880 1098 O +ATOM 4615 CB VAL B 205 10.910 -6.871 68.276 1.00 65.29 C +ANISOU 4615 CB VAL B 205 9550 7922 7333 88 2289 967 C +ATOM 4616 CG1 VAL B 205 11.060 -8.279 68.855 1.00 65.98 C +ANISOU 4616 CG1 VAL B 205 9855 7873 7341 33 2407 991 C +ATOM 4617 CG2 VAL B 205 11.394 -6.817 66.832 1.00 63.62 C +ANISOU 4617 CG2 VAL B 205 9233 7804 7132 43 2018 913 C +ATOM 4618 N VAL B 206 9.222 -5.884 70.734 1.00 72.16 N +ANISOU 4618 N VAL B 206 10405 8690 8321 158 2864 1055 N +ATOM 4619 CA VAL B 206 8.742 -6.079 72.083 1.00 75.80 C +ANISOU 4619 CA VAL B 206 11008 9058 8733 162 3167 1092 C +ATOM 4620 C VAL B 206 7.253 -5.769 72.156 1.00 79.51 C +ANISOU 4620 C VAL B 206 11202 9507 9500 90 3377 1128 C +ATOM 4621 O VAL B 206 6.465 -6.625 72.550 1.00 81.32 O +ANISOU 4621 O VAL B 206 11421 9653 9823 -19 3565 1177 O +ATOM 4622 CB VAL B 206 9.516 -5.211 73.096 1.00 75.69 C +ANISOU 4622 CB VAL B 206 11219 9058 8481 303 3237 1057 C +ATOM 4623 CG1 VAL B 206 8.896 -5.323 74.490 1.00 77.36 C +ANISOU 4623 CG1 VAL B 206 11577 9182 8632 288 3577 1089 C +ATOM 4624 CG2 VAL B 206 10.982 -5.626 73.116 1.00 74.32 C +ANISOU 4624 CG2 VAL B 206 11305 8905 8027 369 3032 1043 C +ATOM 4625 N ILE B 207 6.875 -4.555 71.765 1.00 81.33 N +ANISOU 4625 N ILE B 207 11198 9805 9896 153 3349 1114 N +ATOM 4626 CA ILE B 207 5.489 -4.099 71.898 1.00 85.92 C +ANISOU 4626 CA ILE B 207 11490 10363 10790 116 3563 1160 C +ATOM 4627 C ILE B 207 4.534 -5.058 71.183 1.00 88.92 C +ANISOU 4627 C ILE B 207 11635 10741 11407 -59 3527 1220 C +ATOM 4628 O ILE B 207 3.515 -5.454 71.739 1.00 92.70 O +ANISOU 4628 O ILE B 207 12020 11148 12053 -140 3782 1266 O +ATOM 4629 CB ILE B 207 5.316 -2.636 71.420 1.00 85.88 C +ANISOU 4629 CB ILE B 207 11249 10423 10955 226 3497 1155 C +ATOM 4630 CG1 ILE B 207 5.968 -1.672 72.433 1.00 85.62 C +ANISOU 4630 CG1 ILE B 207 11450 10353 10727 373 3648 1082 C +ATOM 4631 CG2 ILE B 207 3.842 -2.284 71.249 1.00 88.19 C +ANISOU 4631 CG2 ILE B 207 11165 10703 11641 182 3657 1231 C +ATOM 4632 CD1 ILE B 207 6.188 -0.259 71.924 1.00 84.93 C +ANISOU 4632 CD1 ILE B 207 11214 10314 10741 493 3540 1059 C +ATOM 4633 N LEU B 208 4.890 -5.453 69.972 1.00 89.69 N +ANISOU 4633 N LEU B 208 11654 10917 11505 -132 3220 1211 N +ATOM 4634 CA LEU B 208 4.118 -6.435 69.222 1.00 92.57 C +ANISOU 4634 CA LEU B 208 11833 11287 12050 -330 3149 1244 C +ATOM 4635 C LEU B 208 3.996 -7.741 69.990 1.00 93.35 C +ANISOU 4635 C LEU B 208 12146 11252 12070 -431 3349 1249 C +ATOM 4636 O LEU B 208 2.926 -8.335 70.053 1.00 95.48 O +ANISOU 4636 O LEU B 208 12249 11475 12553 -578 3492 1295 O +ATOM 4637 CB LEU B 208 4.767 -6.680 67.862 1.00 93.17 C +ANISOU 4637 CB LEU B 208 11882 11463 12054 -393 2792 1203 C +ATOM 4638 CG LEU B 208 3.990 -7.541 66.865 1.00 96.23 C +ANISOU 4638 CG LEU B 208 12057 11887 12619 -622 2663 1216 C +ATOM 4639 CD1 LEU B 208 2.609 -6.974 66.547 1.00 98.78 C +ANISOU 4639 CD1 LEU B 208 11964 12281 13287 -693 2692 1307 C +ATOM 4640 CD2 LEU B 208 4.819 -7.687 65.599 1.00 94.72 C +ANISOU 4640 CD2 LEU B 208 11907 11792 12287 -670 2331 1152 C +ATOM 4641 N GLY B 209 5.097 -8.183 70.577 1.00 92.63 N +ANISOU 4641 N GLY B 209 12415 11098 11682 -354 3356 1216 N +ATOM 4642 CA GLY B 209 5.062 -9.315 71.498 1.00 94.36 C +ANISOU 4642 CA GLY B 209 12876 11175 11801 -416 3573 1249 C +ATOM 4643 C GLY B 209 5.128 -10.665 70.815 1.00 95.16 C +ANISOU 4643 C GLY B 209 13019 11210 11924 -577 3464 1238 C +ATOM 4644 O GLY B 209 4.852 -10.784 69.620 1.00 93.80 O +ANISOU 4644 O GLY B 209 12634 11110 11895 -692 3259 1202 O +ATOM 4645 N LYS B 210 5.501 -11.677 71.600 1.00 96.98 N +ANISOU 4645 N LYS B 210 13541 11301 12006 -590 3608 1273 N +ATOM 4646 CA LYS B 210 5.689 -13.058 71.131 1.00 97.55 C +ANISOU 4646 CA LYS B 210 13720 11260 12082 -727 3553 1263 C +ATOM 4647 C LYS B 210 6.824 -13.181 70.099 1.00 94.96 C +ANISOU 4647 C LYS B 210 13467 10981 11630 -685 3248 1181 C +ATOM 4648 O LYS B 210 6.862 -14.140 69.321 1.00 95.65 O +ANISOU 4648 O LYS B 210 13562 11002 11776 -823 3161 1134 O +ATOM 4649 CB LYS B 210 4.375 -13.624 70.571 1.00 99.51 C +ANISOU 4649 CB LYS B 210 13696 11483 12628 -961 3617 1263 C +ATOM 4650 N HIS B 211 7.761 -12.228 70.117 1.00 91.94 N +ANISOU 4650 N HIS B 211 13152 10702 11076 -502 3107 1157 N +ATOM 4651 CA HIS B 211 8.876 -12.210 69.162 1.00 88.99 C +ANISOU 4651 CA HIS B 211 12838 10386 10587 -448 2835 1081 C +ATOM 4652 C HIS B 211 10.256 -12.227 69.816 1.00 84.41 C +ANISOU 4652 C HIS B 211 12554 9771 9746 -262 2799 1101 C +ATOM 4653 O HIS B 211 11.156 -11.509 69.385 1.00 81.70 O +ANISOU 4653 O HIS B 211 12217 9532 9292 -147 2609 1053 O +ATOM 4654 CB HIS B 211 8.731 -11.012 68.221 1.00 89.60 C +ANISOU 4654 CB HIS B 211 12657 10646 10741 -430 2637 1029 C +ATOM 4655 CG HIS B 211 7.652 -11.197 67.210 1.00 93.25 C +ANISOU 4655 CG HIS B 211 12831 11160 11437 -632 2566 1007 C +ATOM 4656 ND1 HIS B 211 6.333 -10.889 67.461 1.00 97.01 N +ANISOU 4656 ND1 HIS B 211 13062 11658 12138 -716 2705 1066 N +ATOM 4657 CD2 HIS B 211 7.687 -11.713 65.961 1.00 95.10 C +ANISOU 4657 CD2 HIS B 211 12989 11432 11713 -782 2374 934 C +ATOM 4658 CE1 HIS B 211 5.604 -11.192 66.402 1.00 98.48 C +ANISOU 4658 CE1 HIS B 211 13014 11904 12498 -910 2575 1041 C +ATOM 4659 NE2 HIS B 211 6.404 -11.681 65.473 1.00 98.13 N +ANISOU 4659 NE2 HIS B 211 13079 11875 12331 -961 2370 955 N +ATOM 4660 N SER B 212 10.412 -13.071 70.840 1.00 82.72 N +ANISOU 4660 N SER B 212 12576 9413 9440 -242 2976 1185 N +ATOM 4661 CA SER B 212 11.712 -13.337 71.452 1.00 79.50 C +ANISOU 4661 CA SER B 212 12448 8957 8798 -85 2927 1234 C +ATOM 4662 C SER B 212 12.138 -14.808 71.426 1.00 78.73 C +ANISOU 4662 C SER B 212 12537 8674 8701 -124 2962 1278 C +ATOM 4663 O SER B 212 13.035 -15.166 70.682 1.00 76.06 O +ANISOU 4663 O SER B 212 12243 8316 8341 -84 2799 1227 O +ATOM 4664 CB SER B 212 11.744 -12.827 72.883 1.00 79.93 C +ANISOU 4664 CB SER B 212 12661 9025 8682 16 3086 1323 C +ATOM 4665 OG SER B 212 11.747 -11.418 72.910 1.00 79.48 O +ANISOU 4665 OG SER B 212 12487 9123 8586 95 3028 1266 O +ATOM 4666 N ARG B 213 11.502 -15.660 72.230 1.00 79.76 N +ANISOU 4666 N ARG B 213 12778 8655 8870 -202 3191 1376 N +ATOM 4667 CA ARG B 213 12.000 -17.041 72.480 1.00 80.35 C +ANISOU 4667 CA ARG B 213 13079 8521 8927 -205 3257 1458 C +ATOM 4668 C ARG B 213 12.769 -17.778 71.350 1.00 78.26 C +ANISOU 4668 C ARG B 213 12828 8174 8731 -215 3098 1373 C +ATOM 4669 O ARG B 213 13.980 -18.018 71.476 1.00 77.82 O +ANISOU 4669 O ARG B 213 12935 8078 8554 -59 2999 1418 O +ATOM 4670 CB ARG B 213 10.866 -17.944 72.997 1.00 83.32 C +ANISOU 4670 CB ARG B 213 13480 8737 9441 -371 3523 1532 C +ATOM 4671 CG ARG B 213 11.334 -19.203 73.731 1.00 85.38 C +ANISOU 4671 CG ARG B 213 14025 8773 9641 -338 3650 1679 C +ATOM 4672 CD ARG B 213 11.965 -18.892 75.090 1.00 85.89 C +ANISOU 4672 CD ARG B 213 14324 8869 9440 -167 3698 1840 C +ATOM 4673 NE ARG B 213 13.412 -19.116 75.151 1.00 85.08 N +ANISOU 4673 NE ARG B 213 14396 8745 9185 17 3518 1905 N +ATOM 4674 CZ ARG B 213 14.198 -18.766 76.177 1.00 84.80 C +ANISOU 4674 CZ ARG B 213 14550 8775 8894 175 3475 2037 C +ATOM 4675 NH1 ARG B 213 13.708 -18.153 77.253 1.00 84.38 N +ANISOU 4675 NH1 ARG B 213 14570 8810 8679 168 3611 2103 N +ATOM 4676 NH2 ARG B 213 15.500 -19.031 76.120 1.00 84.56 N +ANISOU 4676 NH2 ARG B 213 14636 8724 8770 334 3295 2101 N +ATOM 4677 N GLY B 214 12.087 -18.154 70.270 1.00 76.56 N +ANISOU 4677 N GLY B 214 12446 7933 8709 -403 3079 1252 N +ATOM 4678 CA GLY B 214 12.735 -18.854 69.153 1.00 74.48 C +ANISOU 4678 CA GLY B 214 12207 7585 8505 -442 2960 1142 C +ATOM 4679 C GLY B 214 13.358 -17.979 68.069 1.00 70.82 C +ANISOU 4679 C GLY B 214 11608 7306 7991 -394 2714 1008 C +ATOM 4680 O GLY B 214 13.677 -18.473 66.989 1.00 70.66 O +ANISOU 4680 O GLY B 214 11575 7240 8031 -474 2630 886 O +ATOM 4681 N TYR B 215 13.530 -16.685 68.351 1.00 67.49 N +ANISOU 4681 N TYR B 215 11099 7084 7458 -272 2614 1026 N +ATOM 4682 CA TYR B 215 14.016 -15.721 67.370 1.00 64.13 C +ANISOU 4682 CA TYR B 215 10532 6843 6990 -232 2392 916 C +ATOM 4683 C TYR B 215 15.478 -15.395 67.569 1.00 61.51 C +ANISOU 4683 C TYR B 215 10335 6544 6493 -16 2272 939 C +ATOM 4684 O TYR B 215 16.034 -15.571 68.657 1.00 61.32 O +ANISOU 4684 O TYR B 215 10485 6456 6358 124 2337 1061 O +ATOM 4685 CB TYR B 215 13.202 -14.434 67.414 1.00 63.21 C +ANISOU 4685 CB TYR B 215 10199 6918 6898 -251 2357 914 C +ATOM 4686 CG TYR B 215 11.799 -14.626 66.922 1.00 64.77 C +ANISOU 4686 CG TYR B 215 10192 7125 7292 -473 2418 880 C +ATOM 4687 CD1 TYR B 215 10.874 -15.364 67.655 1.00 67.10 C +ANISOU 4687 CD1 TYR B 215 10514 7287 7692 -578 2639 952 C +ATOM 4688 CD2 TYR B 215 11.392 -14.084 65.725 1.00 64.57 C +ANISOU 4688 CD2 TYR B 215 9940 7245 7347 -587 2250 789 C +ATOM 4689 CE1 TYR B 215 9.574 -15.537 67.209 1.00 68.61 C +ANISOU 4689 CE1 TYR B 215 10490 7495 8084 -793 2690 925 C +ATOM 4690 CE2 TYR B 215 10.097 -14.258 65.263 1.00 66.22 C +ANISOU 4690 CE2 TYR B 215 9937 7480 7742 -801 2278 772 C +ATOM 4691 CZ TYR B 215 9.194 -14.979 66.009 1.00 68.04 C +ANISOU 4691 CZ TYR B 215 10178 7581 8094 -903 2497 836 C +ATOM 4692 OH TYR B 215 7.919 -15.134 65.533 1.00 69.86 O +ANISOU 4692 OH TYR B 215 10170 7847 8527 -1123 2514 822 O +ATOM 4693 N HIS B 216 16.094 -14.914 66.491 1.00 58.91 N +ANISOU 4693 N HIS B 216 9917 6322 6143 -1 2091 827 N +ATOM 4694 CA HIS B 216 17.487 -14.534 66.519 1.00 56.82 C +ANISOU 4694 CA HIS B 216 9735 6104 5746 187 1965 834 C +ATOM 4695 C HIS B 216 17.689 -13.258 65.707 1.00 54.73 C +ANISOU 4695 C HIS B 216 9301 6051 5440 201 1784 745 C +ATOM 4696 O HIS B 216 17.389 -13.232 64.525 1.00 54.85 O +ANISOU 4696 O HIS B 216 9196 6120 5522 69 1706 635 O +ATOM 4697 CB HIS B 216 18.320 -15.666 65.959 1.00 56.84 C +ANISOU 4697 CB HIS B 216 9860 5943 5791 200 1972 790 C +ATOM 4698 CG HIS B 216 19.783 -15.522 66.220 1.00 55.92 C +ANISOU 4698 CG HIS B 216 9841 5833 5572 413 1880 838 C +ATOM 4699 ND1 HIS B 216 20.648 -16.595 66.173 1.00 57.05 N +ANISOU 4699 ND1 HIS B 216 10121 5790 5762 492 1927 863 N +ATOM 4700 CD2 HIS B 216 20.541 -14.439 66.511 1.00 54.05 C +ANISOU 4700 CD2 HIS B 216 9570 5758 5207 559 1744 865 C +ATOM 4701 CE1 HIS B 216 21.874 -16.176 66.424 1.00 56.08 C +ANISOU 4701 CE1 HIS B 216 10026 5729 5550 682 1815 915 C +ATOM 4702 NE2 HIS B 216 21.836 -14.872 66.639 1.00 54.26 N +ANISOU 4702 NE2 HIS B 216 9698 5712 5203 717 1698 912 N +ATOM 4703 N TYR B 217 18.169 -12.201 66.359 1.00 53.48 N +ANISOU 4703 N TYR B 217 9142 6012 5163 347 1721 797 N +ATOM 4704 CA TYR B 217 18.485 -10.933 65.703 1.00 51.52 C +ANISOU 4704 CA TYR B 217 8753 5947 4873 383 1558 731 C +ATOM 4705 C TYR B 217 19.995 -10.758 65.658 1.00 50.92 C +ANISOU 4705 C TYR B 217 8765 5896 4685 540 1441 725 C +ATOM 4706 O TYR B 217 20.660 -10.784 66.693 1.00 50.51 O +ANISOU 4706 O TYR B 217 8842 5815 4532 675 1458 814 O +ATOM 4707 CB TYR B 217 17.820 -9.765 66.436 1.00 50.78 C +ANISOU 4707 CB TYR B 217 8574 5960 4758 412 1591 779 C +ATOM 4708 CG TYR B 217 16.330 -9.929 66.517 1.00 51.92 C +ANISOU 4708 CG TYR B 217 8604 6079 5044 267 1722 797 C +ATOM 4709 CD1 TYR B 217 15.504 -9.479 65.487 1.00 51.93 C +ANISOU 4709 CD1 TYR B 217 8382 6173 5173 139 1648 743 C +ATOM 4710 CD2 TYR B 217 15.744 -10.571 67.599 1.00 53.05 C +ANISOU 4710 CD2 TYR B 217 8852 6105 5197 250 1916 881 C +ATOM 4711 CE1 TYR B 217 14.132 -9.658 65.556 1.00 53.22 C +ANISOU 4711 CE1 TYR B 217 8409 6317 5492 2 1760 771 C +ATOM 4712 CE2 TYR B 217 14.392 -10.765 67.664 1.00 54.19 C +ANISOU 4712 CE2 TYR B 217 8875 6219 5492 111 2049 899 C +ATOM 4713 CZ TYR B 217 13.589 -10.314 66.649 1.00 54.42 C +ANISOU 4713 CZ TYR B 217 8662 6345 5668 -11 1968 843 C +ATOM 4714 OH TYR B 217 12.232 -10.522 66.734 1.00 56.18 O +ANISOU 4714 OH TYR B 217 8737 6543 6063 -152 2096 872 O +ATOM 4715 N MET B 218 20.531 -10.626 64.446 1.00 51.24 N +ANISOU 4715 N MET B 218 8733 5992 4743 512 1323 623 N +ATOM 4716 CA MET B 218 21.945 -10.336 64.246 1.00 51.42 C +ANISOU 4716 CA MET B 218 8794 6056 4685 650 1212 605 C +ATOM 4717 C MET B 218 22.012 -8.880 63.809 1.00 50.60 C +ANISOU 4717 C MET B 218 8550 6139 4535 661 1082 565 C +ATOM 4718 O MET B 218 21.456 -8.515 62.777 1.00 49.53 O +ANISOU 4718 O MET B 218 8286 6081 4449 541 1028 494 O +ATOM 4719 CB MET B 218 22.544 -11.251 63.190 1.00 52.38 C +ANISOU 4719 CB MET B 218 8948 6089 4863 610 1209 514 C +ATOM 4720 CG MET B 218 24.033 -11.029 62.952 1.00 52.31 C +ANISOU 4720 CG MET B 218 8961 6111 4803 756 1118 497 C +ATOM 4721 SD MET B 218 24.712 -12.162 61.711 1.00 55.20 S +ANISOU 4721 SD MET B 218 9374 6343 5253 708 1169 373 S +ATOM 4722 CE MET B 218 24.386 -13.765 62.472 1.00 57.29 C +ANISOU 4722 CE MET B 218 9801 6344 5621 712 1352 450 C +ATOM 4723 N LEU B 219 22.678 -8.060 64.618 1.00 50.89 N +ANISOU 4723 N LEU B 219 8616 6244 4474 795 1031 617 N +ATOM 4724 CA LEU B 219 22.670 -6.623 64.457 1.00 50.65 C +ANISOU 4724 CA LEU B 219 8471 6363 4408 812 939 592 C +ATOM 4725 C LEU B 219 23.995 -6.190 63.861 1.00 51.47 C +ANISOU 4725 C LEU B 219 8558 6537 4461 890 807 545 C +ATOM 4726 O LEU B 219 25.008 -6.123 64.554 1.00 51.70 O +ANISOU 4726 O LEU B 219 8665 6566 4410 1012 767 585 O +ATOM 4727 CB LEU B 219 22.454 -5.956 65.806 1.00 50.45 C +ANISOU 4727 CB LEU B 219 8503 6358 4306 883 993 661 C +ATOM 4728 CG LEU B 219 21.281 -6.504 66.625 1.00 51.83 C +ANISOU 4728 CG LEU B 219 8728 6445 4519 823 1161 722 C +ATOM 4729 CD1 LEU B 219 21.213 -5.813 67.986 1.00 51.97 C +ANISOU 4729 CD1 LEU B 219 8835 6487 4424 892 1229 775 C +ATOM 4730 CD2 LEU B 219 19.969 -6.351 65.862 1.00 51.98 C +ANISOU 4730 CD2 LEU B 219 8579 6483 4686 684 1204 689 C +ATOM 4731 N ALA B 220 23.970 -5.877 62.568 1.00 53.09 N +ANISOU 4731 N ALA B 220 8654 6810 4707 809 736 468 N +ATOM 4732 CA ALA B 220 25.174 -5.584 61.797 1.00 53.29 C +ANISOU 4732 CA ALA B 220 8656 6893 4698 858 637 411 C +ATOM 4733 C ALA B 220 25.521 -4.113 61.905 1.00 52.90 C +ANISOU 4733 C ALA B 220 8528 6971 4600 909 543 418 C +ATOM 4734 O ALA B 220 25.249 -3.330 61.001 1.00 54.42 O +ANISOU 4734 O ALA B 220 8609 7253 4812 840 480 385 O +ATOM 4735 CB ALA B 220 24.961 -5.980 60.343 1.00 53.27 C +ANISOU 4735 CB ALA B 220 8600 6903 4735 724 621 322 C +ATOM 4736 N ASN B 221 26.124 -3.749 63.021 1.00 53.40 N +ANISOU 4736 N ASN B 221 8655 7037 4596 1022 530 466 N +ATOM 4737 CA ASN B 221 26.423 -2.369 63.297 1.00 53.82 C +ANISOU 4737 CA ASN B 221 8656 7188 4604 1062 460 463 C +ATOM 4738 C ASN B 221 27.395 -2.330 64.454 1.00 53.40 C +ANISOU 4738 C ASN B 221 8702 7133 4452 1173 428 503 C +ATOM 4739 O ASN B 221 27.136 -2.908 65.474 1.00 55.07 O +ANISOU 4739 O ASN B 221 9023 7283 4616 1202 492 563 O +ATOM 4740 CB ASN B 221 25.149 -1.602 63.654 1.00 55.34 C +ANISOU 4740 CB ASN B 221 8795 7395 4833 1009 523 483 C +ATOM 4741 CG ASN B 221 25.379 -0.100 63.727 1.00 55.36 C +ANISOU 4741 CG ASN B 221 8734 7478 4822 1036 468 466 C +ATOM 4742 OD1 ASN B 221 26.167 0.357 64.552 1.00 55.29 O +ANISOU 4742 OD1 ASN B 221 8796 7487 4724 1106 439 462 O +ATOM 4743 ND2 ASN B 221 24.700 0.672 62.862 1.00 54.65 N +ANISOU 4743 ND2 ASN B 221 8507 7433 4821 973 448 461 N +ATOM 4744 N LEU B 222 28.507 -1.628 64.275 1.00 52.70 N +ANISOU 4744 N LEU B 222 8573 7119 4329 1223 322 476 N +ATOM 4745 CA LEU B 222 29.587 -1.564 65.245 1.00 52.75 C +ANISOU 4745 CA LEU B 222 8648 7150 4243 1315 250 515 C +ATOM 4746 C LEU B 222 29.224 -0.781 66.511 1.00 53.94 C +ANISOU 4746 C LEU B 222 8879 7329 4284 1315 266 534 C +ATOM 4747 O LEU B 222 29.934 -0.868 67.520 1.00 53.01 O +ANISOU 4747 O LEU B 222 8852 7233 4055 1370 208 580 O +ATOM 4748 CB LEU B 222 30.847 -0.982 64.598 1.00 52.02 C +ANISOU 4748 CB LEU B 222 8463 7135 4165 1347 135 472 C +ATOM 4749 CG LEU B 222 31.399 -1.828 63.447 1.00 52.49 C +ANISOU 4749 CG LEU B 222 8465 7159 4317 1356 142 445 C +ATOM 4750 CD1 LEU B 222 32.371 -1.038 62.578 1.00 52.50 C +ANISOU 4750 CD1 LEU B 222 8353 7245 4346 1355 65 387 C +ATOM 4751 CD2 LEU B 222 32.035 -3.101 63.975 1.00 53.73 C +ANISOU 4751 CD2 LEU B 222 8692 7231 4489 1451 154 515 C +ATOM 4752 N GLY B 223 28.117 -0.038 66.465 1.00 55.00 N +ANISOU 4752 N GLY B 223 8982 7463 4452 1250 348 501 N +ATOM 4753 CA GLY B 223 27.582 0.645 67.645 1.00 56.00 C +ANISOU 4753 CA GLY B 223 9197 7589 4490 1239 419 501 C +ATOM 4754 C GLY B 223 26.781 -0.233 68.587 1.00 58.19 C +ANISOU 4754 C GLY B 223 9601 7792 4716 1233 546 565 C +ATOM 4755 O GLY B 223 25.842 0.233 69.230 1.00 59.16 O +ANISOU 4755 O GLY B 223 9763 7889 4823 1197 672 555 O +ATOM 4756 N PHE B 224 27.179 -1.495 68.698 1.00 59.10 N +ANISOU 4756 N PHE B 224 9782 7860 4812 1272 527 636 N +ATOM 4757 CA PHE B 224 26.514 -2.469 69.556 1.00 61.10 C +ANISOU 4757 CA PHE B 224 10167 8029 5019 1266 647 717 C +ATOM 4758 C PHE B 224 26.140 -1.961 70.959 1.00 60.38 C +ANISOU 4758 C PHE B 224 10221 7954 4767 1251 728 735 C +ATOM 4759 O PHE B 224 25.007 -2.159 71.387 1.00 60.64 O +ANISOU 4759 O PHE B 224 10297 7924 4817 1202 896 751 O +ATOM 4760 CB PHE B 224 27.389 -3.728 69.664 1.00 63.59 C +ANISOU 4760 CB PHE B 224 10551 8294 5315 1338 582 807 C +ATOM 4761 CG PHE B 224 26.744 -4.853 70.404 1.00 65.86 C +ANISOU 4761 CG PHE B 224 10972 8472 5577 1331 708 908 C +ATOM 4762 CD1 PHE B 224 25.658 -5.525 69.863 1.00 66.33 C +ANISOU 4762 CD1 PHE B 224 10995 8434 5771 1261 844 897 C +ATOM 4763 CD2 PHE B 224 27.236 -5.251 71.644 1.00 70.65 C +ANISOU 4763 CD2 PHE B 224 11744 9079 6020 1385 682 1022 C +ATOM 4764 CE1 PHE B 224 25.046 -6.552 70.552 1.00 69.71 C +ANISOU 4764 CE1 PHE B 224 11548 8752 6188 1244 975 991 C +ATOM 4765 CE2 PHE B 224 26.632 -6.295 72.346 1.00 71.83 C +ANISOU 4765 CE2 PHE B 224 12030 9120 6141 1375 808 1132 C +ATOM 4766 CZ PHE B 224 25.541 -6.950 71.791 1.00 71.89 C +ANISOU 4766 CZ PHE B 224 11997 9015 6301 1306 965 1113 C +ATOM 4767 N THR B 225 27.061 -1.298 71.657 1.00 59.49 N +ANISOU 4767 N THR B 225 10181 7925 4497 1279 620 724 N +ATOM 4768 CA THR B 225 26.813 -0.912 73.066 1.00 60.82 C +ANISOU 4768 CA THR B 225 10529 8114 4465 1247 695 734 C +ATOM 4769 C THR B 225 25.864 0.290 73.267 1.00 61.28 C +ANISOU 4769 C THR B 225 10571 8166 4544 1182 847 625 C +ATOM 4770 O THR B 225 25.513 0.600 74.385 1.00 62.76 O +ANISOU 4770 O THR B 225 10914 8353 4575 1143 957 612 O +ATOM 4771 CB THR B 225 28.120 -0.683 73.875 1.00 60.65 C +ANISOU 4771 CB THR B 225 10614 8194 4236 1275 516 764 C +ATOM 4772 OG1 THR B 225 28.832 0.431 73.350 1.00 58.87 O +ANISOU 4772 OG1 THR B 225 10275 8047 4043 1268 395 660 O +ATOM 4773 CG2 THR B 225 29.031 -1.913 73.857 1.00 60.68 C +ANISOU 4773 CG2 THR B 225 10633 8189 4232 1358 381 903 C +ATOM 4774 N ASP B 226 25.459 0.955 72.192 1.00 62.21 N +ANISOU 4774 N ASP B 226 10505 8275 4856 1171 860 554 N +ATOM 4775 CA ASP B 226 24.403 1.997 72.225 1.00 63.36 C +ANISOU 4775 CA ASP B 226 10593 8384 5096 1128 1026 476 C +ATOM 4776 C ASP B 226 23.021 1.442 71.864 1.00 60.48 C +ANISOU 4776 C ASP B 226 10138 7935 4904 1100 1193 518 C +ATOM 4777 O ASP B 226 22.042 2.187 71.799 1.00 60.95 O +ANISOU 4777 O ASP B 226 10110 7956 5092 1075 1338 479 O +ATOM 4778 CB ASP B 226 24.714 3.152 71.232 1.00 65.84 C +ANISOU 4778 CB ASP B 226 10739 8734 5541 1133 936 399 C +ATOM 4779 CG ASP B 226 26.113 3.767 71.436 1.00 69.59 C +ANISOU 4779 CG ASP B 226 11266 9292 5879 1146 763 349 C +ATOM 4780 OD1 ASP B 226 26.424 4.219 72.575 1.00 73.13 O +ANISOU 4780 OD1 ASP B 226 11877 9764 6143 1119 785 305 O +ATOM 4781 OD2 ASP B 226 26.890 3.787 70.439 1.00 72.88 O +ANISOU 4781 OD2 ASP B 226 11562 9756 6373 1171 608 350 O +ATOM 4782 N ILE B 227 22.940 0.144 71.608 1.00 57.92 N +ANISOU 4782 N ILE B 227 9821 7577 4606 1101 1176 600 N +ATOM 4783 CA ILE B 227 21.684 -0.465 71.226 1.00 56.99 C +ANISOU 4783 CA ILE B 227 9611 7386 4656 1053 1316 637 C +ATOM 4784 C ILE B 227 20.939 -0.936 72.465 1.00 59.02 C +ANISOU 4784 C ILE B 227 10025 7577 4823 1024 1521 684 C +ATOM 4785 O ILE B 227 21.483 -1.693 73.283 1.00 60.23 O +ANISOU 4785 O ILE B 227 10365 7721 4797 1042 1506 748 O +ATOM 4786 CB ILE B 227 21.905 -1.653 70.282 1.00 55.67 C +ANISOU 4786 CB ILE B 227 9383 7195 4573 1046 1220 684 C +ATOM 4787 CG1 ILE B 227 22.511 -1.160 68.963 1.00 54.06 C +ANISOU 4787 CG1 ILE B 227 9022 7058 4459 1056 1049 632 C +ATOM 4788 CG2 ILE B 227 20.585 -2.363 70.023 1.00 56.24 C +ANISOU 4788 CG2 ILE B 227 9378 7189 4800 970 1367 720 C +ATOM 4789 CD1 ILE B 227 22.856 -2.258 67.977 1.00 53.27 C +ANISOU 4789 CD1 ILE B 227 8880 6934 4423 1041 964 649 C +ATOM 4790 N LEU B 228 19.689 -0.493 72.595 1.00 59.75 N +ANISOU 4790 N LEU B 228 10032 7621 5046 981 1716 664 N +ATOM 4791 CA LEU B 228 18.857 -0.826 73.757 1.00 61.66 C +ANISOU 4791 CA LEU B 228 10409 7796 5221 943 1955 697 C +ATOM 4792 C LEU B 228 18.174 -2.172 73.532 1.00 61.23 C +ANISOU 4792 C LEU B 228 10327 7667 5268 894 2027 787 C +ATOM 4793 O LEU B 228 17.226 -2.282 72.773 1.00 60.01 O +ANISOU 4793 O LEU B 228 9974 7481 5343 846 2083 791 O +ATOM 4794 CB LEU B 228 17.812 0.270 74.005 1.00 62.89 C +ANISOU 4794 CB LEU B 228 10468 7918 5506 925 2164 632 C +ATOM 4795 CG LEU B 228 18.322 1.730 74.094 1.00 62.67 C +ANISOU 4795 CG LEU B 228 10439 7932 5438 963 2125 527 C +ATOM 4796 CD1 LEU B 228 17.179 2.678 74.425 1.00 63.74 C +ANISOU 4796 CD1 LEU B 228 10486 7996 5734 954 2384 473 C +ATOM 4797 CD2 LEU B 228 19.468 1.907 75.090 1.00 63.25 C +ANISOU 4797 CD2 LEU B 228 10774 8061 5196 972 2050 488 C +ATOM 4798 N LEU B 229 18.660 -3.203 74.195 1.00 62.59 N +ANISOU 4798 N LEU B 229 10696 7810 5275 900 2018 867 N +ATOM 4799 CA LEU B 229 18.198 -4.544 73.904 1.00 64.23 C +ANISOU 4799 CA LEU B 229 10892 7929 5583 854 2067 950 C +ATOM 4800 C LEU B 229 17.877 -5.387 75.137 1.00 66.20 C +ANISOU 4800 C LEU B 229 11361 8101 5690 825 2246 1049 C +ATOM 4801 O LEU B 229 17.876 -6.615 75.049 1.00 67.37 O +ANISOU 4801 O LEU B 229 11564 8165 5867 805 2253 1138 O +ATOM 4802 CB LEU B 229 19.226 -5.241 72.992 1.00 64.04 C +ANISOU 4802 CB LEU B 229 10842 7913 5574 896 1839 967 C +ATOM 4803 CG LEU B 229 20.708 -5.082 73.352 1.00 63.80 C +ANISOU 4803 CG LEU B 229 10946 7951 5341 991 1653 983 C +ATOM 4804 CD1 LEU B 229 20.981 -5.719 74.705 1.00 65.93 C +ANISOU 4804 CD1 LEU B 229 11467 8187 5394 1009 1720 1096 C +ATOM 4805 CD2 LEU B 229 21.601 -5.673 72.280 1.00 62.61 C +ANISOU 4805 CD2 LEU B 229 10718 7799 5270 1033 1465 983 C +ATOM 4806 N GLU B 230 17.570 -4.744 76.264 1.00 67.91 N +ANISOU 4806 N GLU B 230 11711 8334 5756 813 2409 1034 N +ATOM 4807 CA GLU B 230 17.239 -5.472 77.492 1.00 71.13 C +ANISOU 4807 CA GLU B 230 12351 8679 5996 773 2597 1134 C +ATOM 4808 C GLU B 230 15.828 -6.068 77.408 1.00 71.81 C +ANISOU 4808 C GLU B 230 12333 8655 6294 683 2845 1166 C +ATOM 4809 O GLU B 230 15.598 -7.213 77.823 1.00 72.66 O +ANISOU 4809 O GLU B 230 12561 8672 6372 642 2940 1280 O +ATOM 4810 CB GLU B 230 17.391 -4.582 78.744 1.00 73.85 C +ANISOU 4810 CB GLU B 230 12898 9084 6076 769 2703 1091 C +ATOM 4811 CG GLU B 230 17.427 -5.368 80.052 1.00 77.56 C +ANISOU 4811 CG GLU B 230 13665 9522 6281 733 2828 1216 C +ATOM 4812 CD GLU B 230 17.589 -4.523 81.314 1.00 80.51 C +ANISOU 4812 CD GLU B 230 14273 9967 6348 701 2934 1163 C +ATOM 4813 OE1 GLU B 230 17.055 -3.387 81.392 1.00 81.72 O +ANISOU 4813 OE1 GLU B 230 14358 10134 6557 677 3080 1017 O +ATOM 4814 OE2 GLU B 230 18.242 -5.021 82.260 1.00 81.77 O +ANISOU 4814 OE2 GLU B 230 14697 10164 6206 693 2877 1272 O +ATOM 4815 N ARG B 231 14.890 -5.305 76.865 1.00 71.47 N +ANISOU 4815 N ARG B 231 12057 8616 6480 651 2946 1079 N +ATOM 4816 CA ARG B 231 13.506 -5.766 76.763 1.00 74.05 C +ANISOU 4816 CA ARG B 231 12242 8854 7039 557 3177 1109 C +ATOM 4817 C ARG B 231 13.354 -6.946 75.798 1.00 73.51 C +ANISOU 4817 C ARG B 231 12058 8724 7148 502 3075 1164 C +ATOM 4818 O ARG B 231 12.524 -7.823 76.012 1.00 75.71 O +ANISOU 4818 O ARG B 231 12335 8905 7527 411 3251 1229 O +ATOM 4819 CB ARG B 231 12.579 -4.623 76.361 1.00 75.38 C +ANISOU 4819 CB ARG B 231 12154 9046 7439 549 3284 1021 C +ATOM 4820 CG ARG B 231 12.464 -3.567 77.438 1.00 78.71 C +ANISOU 4820 CG ARG B 231 12704 9481 7719 579 3481 956 C +ATOM 4821 CD ARG B 231 11.468 -2.458 77.117 1.00 80.87 C +ANISOU 4821 CD ARG B 231 12717 9743 8263 586 3635 882 C +ATOM 4822 NE ARG B 231 10.068 -2.866 77.264 1.00 84.16 N +ANISOU 4822 NE ARG B 231 12982 10076 8917 507 3908 931 N +ATOM 4823 CZ ARG B 231 9.442 -3.102 78.423 1.00 88.22 C +ANISOU 4823 CZ ARG B 231 13650 10519 9349 457 4229 951 C +ATOM 4824 NH1 ARG B 231 10.074 -3.001 79.595 1.00 89.91 N +ANISOU 4824 NH1 ARG B 231 14204 10741 9217 468 4317 929 N +ATOM 4825 NH2 ARG B 231 8.161 -3.463 78.414 1.00 90.55 N +ANISOU 4825 NH2 ARG B 231 13758 10740 9907 382 4467 997 N +ATOM 4826 N VAL B 232 14.155 -6.966 74.737 1.00 71.03 N +ANISOU 4826 N VAL B 232 11654 8460 6872 544 2807 1127 N +ATOM 4827 CA VAL B 232 14.156 -8.085 73.795 1.00 70.85 C +ANISOU 4827 CA VAL B 232 11556 8374 6987 485 2707 1154 C +ATOM 4828 C VAL B 232 14.773 -9.349 74.407 1.00 72.12 C +ANISOU 4828 C VAL B 232 11967 8432 7000 500 2722 1261 C +ATOM 4829 O VAL B 232 14.279 -10.453 74.182 1.00 72.38 O +ANISOU 4829 O VAL B 232 11996 8349 7155 413 2803 1309 O +ATOM 4830 CB VAL B 232 14.891 -7.723 72.480 1.00 67.41 C +ANISOU 4830 CB VAL B 232 10974 8022 6614 522 2436 1076 C +ATOM 4831 CG1 VAL B 232 15.083 -8.952 71.610 1.00 66.81 C +ANISOU 4831 CG1 VAL B 232 10884 7868 6630 461 2346 1086 C +ATOM 4832 CG2 VAL B 232 14.112 -6.657 71.741 1.00 66.65 C +ANISOU 4832 CG2 VAL B 232 10608 8008 6708 489 2421 1005 C +ATOM 4833 N MET B 233 15.861 -9.186 75.156 1.00 73.14 N +ANISOU 4833 N MET B 233 12307 8602 6878 605 2635 1304 N +ATOM 4834 CA MET B 233 16.543 -10.329 75.763 1.00 75.93 C +ANISOU 4834 CA MET B 233 12892 8864 7092 642 2623 1437 C +ATOM 4835 C MET B 233 15.696 -11.021 76.828 1.00 76.15 C +ANISOU 4835 C MET B 233 13076 8785 7073 566 2890 1549 C +ATOM 4836 O MET B 233 15.740 -12.246 76.930 1.00 77.07 O +ANISOU 4836 O MET B 233 13297 8766 7219 544 2936 1658 O +ATOM 4837 CB MET B 233 17.874 -9.917 76.377 1.00 79.21 C +ANISOU 4837 CB MET B 233 13478 9372 7246 765 2450 1476 C +ATOM 4838 CG MET B 233 19.028 -9.932 75.387 1.00 80.04 C +ANISOU 4838 CG MET B 233 13495 9519 7395 852 2185 1435 C +ATOM 4839 SD MET B 233 20.616 -9.674 76.212 1.00 86.58 S +ANISOU 4839 SD MET B 233 14514 10446 7936 988 1977 1519 S +ATOM 4840 CE MET B 233 20.486 -10.569 77.781 1.00 87.60 C +ANISOU 4840 CE MET B 233 14946 10495 7843 979 2126 1725 C +ATOM 4841 N HIS B 234 14.929 -10.233 77.590 1.00 74.93 N +ANISOU 4841 N HIS B 234 12934 8677 6859 525 3082 1518 N +ATOM 4842 CA AHIS B 234 14.092 -10.803 78.631 0.50 76.86 C +ANISOU 4842 CA AHIS B 234 13327 8826 7048 444 3365 1618 C +ATOM 4843 CA BHIS B 234 13.993 -10.729 78.621 0.50 76.83 C +ANISOU 4843 CA BHIS B 234 13306 8825 7058 438 3380 1608 C +ATOM 4844 C HIS B 234 13.129 -11.855 78.082 1.00 77.10 C +ANISOU 4844 C HIS B 234 13233 8712 7347 327 3501 1652 C +ATOM 4845 O HIS B 234 12.853 -12.840 78.770 1.00 80.03 O +ANISOU 4845 O HIS B 234 13774 8960 7671 275 3665 1780 O +ATOM 4846 CB AHIS B 234 13.391 -9.704 79.434 0.50 77.49 C +ANISOU 4846 CB AHIS B 234 13418 8974 7049 416 3576 1550 C +ATOM 4847 CB BHIS B 234 13.088 -9.576 79.126 0.50 77.10 C +ANISOU 4847 CB BHIS B 234 13269 8923 7102 398 3593 1516 C +ATOM 4848 CG AHIS B 234 14.197 -9.221 80.604 0.50 77.64 C +ANISOU 4848 CG AHIS B 234 13720 9076 6704 474 3556 1583 C +ATOM 4849 CG BHIS B 234 11.861 -10.018 79.882 0.50 78.86 C +ANISOU 4849 CG BHIS B 234 13533 9046 7383 287 3939 1576 C +ATOM 4850 ND1AHIS B 234 15.328 -8.441 80.469 0.50 75.80 N +ANISOU 4850 ND1AHIS B 234 13516 8968 6316 569 3303 1520 N +ATOM 4851 ND1BHIS B 234 10.657 -10.283 79.263 0.50 78.73 N +ANISOU 4851 ND1BHIS B 234 13263 8958 7690 184 4086 1549 N +ATOM 4852 CD2AHIS B 234 14.046 -9.431 81.930 0.50 79.85 C +ANISOU 4852 CD2AHIS B 234 14273 9338 6727 434 3750 1674 C +ATOM 4853 CD2BHIS B 234 11.645 -10.195 81.207 0.50 80.92 C +ANISOU 4853 CD2BHIS B 234 14052 9275 7417 252 4171 1659 C +ATOM 4854 CE1AHIS B 234 15.830 -8.186 81.661 0.50 77.26 C +ANISOU 4854 CE1AHIS B 234 13973 9213 6167 577 3329 1566 C +ATOM 4855 CE1BHIS B 234 9.761 -10.630 80.169 0.50 80.93 C +ANISOU 4855 CE1BHIS B 234 13631 9156 7960 96 4404 1615 C +ATOM 4856 NE2AHIS B 234 15.070 -8.773 82.566 0.50 79.68 N +ANISOU 4856 NE2AHIS B 234 14442 9439 6393 496 3598 1661 N +ATOM 4857 NE2BHIS B 234 10.335 -10.585 81.357 0.50 82.39 N +ANISOU 4857 NE2BHIS B 234 14137 9362 7806 136 4470 1681 N +ATOM 4858 N GLY B 235 12.673 -11.688 76.849 1.00 74.15 N +ANISOU 4858 N GLY B 235 12579 8353 7240 278 3420 1545 N +ATOM 4859 CA GLY B 235 11.790 -12.670 76.222 1.00 74.07 C +ANISOU 4859 CA GLY B 235 12437 8219 7486 142 3516 1558 C +ATOM 4860 C GLY B 235 12.470 -13.955 75.787 1.00 73.47 C +ANISOU 4860 C GLY B 235 12471 8015 7426 142 3407 1618 C +ATOM 4861 O GLY B 235 11.793 -14.940 75.500 1.00 75.41 O +ANISOU 4861 O GLY B 235 12678 8124 7848 16 3522 1644 O +ATOM 4862 N GLY B 236 13.801 -13.938 75.704 1.00 71.27 N +ANISOU 4862 N GLY B 236 12317 7773 6987 279 3192 1636 N +ATOM 4863 CA GLY B 236 14.582 -15.130 75.378 1.00 71.03 C +ANISOU 4863 CA GLY B 236 12405 7606 6975 312 3102 1705 C +ATOM 4864 C GLY B 236 15.200 -15.168 73.985 1.00 68.47 C +ANISOU 4864 C GLY B 236 11932 7304 6778 332 2881 1583 C +ATOM 4865 O GLY B 236 15.666 -16.219 73.553 1.00 68.91 O +ANISOU 4865 O GLY B 236 12055 7216 6909 334 2849 1610 O +ATOM 4866 N ALA B 237 15.241 -14.026 73.295 1.00 65.55 N +ANISOU 4866 N ALA B 237 11373 7102 6428 348 2740 1453 N +ATOM 4867 CA ALA B 237 15.780 -13.950 71.934 1.00 63.01 C +ANISOU 4867 CA ALA B 237 10910 6823 6206 351 2539 1331 C +ATOM 4868 C ALA B 237 17.285 -14.005 71.948 1.00 61.56 C +ANISOU 4868 C ALA B 237 10850 6654 5883 516 2364 1363 C +ATOM 4869 O ALA B 237 17.908 -13.423 72.829 1.00 60.91 O +ANISOU 4869 O ALA B 237 10879 6654 5610 633 2318 1431 O +ATOM 4870 CB ALA B 237 15.340 -12.656 71.273 1.00 61.52 C +ANISOU 4870 CB ALA B 237 10489 6811 6074 322 2449 1213 C +ATOM 4871 N ASN B 238 17.873 -14.690 70.965 1.00 60.90 N +ANISOU 4871 N ASN B 238 10745 6494 5899 516 2270 1307 N +ATOM 4872 CA ASN B 238 19.320 -14.652 70.781 1.00 60.23 C +ANISOU 4872 CA ASN B 238 10721 6434 5728 674 2098 1319 C +ATOM 4873 C ASN B 238 19.647 -13.326 70.100 1.00 57.83 C +ANISOU 4873 C ASN B 238 10253 6334 5384 704 1926 1196 C +ATOM 4874 O ASN B 238 18.855 -12.817 69.292 1.00 56.63 O +ANISOU 4874 O ASN B 238 9927 6256 5333 587 1919 1084 O +ATOM 4875 CB ASN B 238 19.812 -15.814 69.931 1.00 61.33 C +ANISOU 4875 CB ASN B 238 10889 6406 6006 664 2094 1286 C +ATOM 4876 CG ASN B 238 19.593 -17.173 70.594 1.00 64.70 C +ANISOU 4876 CG ASN B 238 11491 6599 6492 648 2268 1422 C +ATOM 4877 OD1 ASN B 238 20.237 -17.522 71.596 1.00 66.33 O +ANISOU 4877 OD1 ASN B 238 11862 6746 6592 781 2276 1593 O +ATOM 4878 ND2 ASN B 238 18.690 -17.961 70.024 1.00 66.12 N +ANISOU 4878 ND2 ASN B 238 11638 6642 6843 477 2401 1352 N +ATOM 4879 N ILE B 239 20.776 -12.733 70.463 1.00 56.75 N +ANISOU 4879 N ILE B 239 10164 6292 5103 852 1786 1230 N +ATOM 4880 CA ILE B 239 21.210 -11.500 69.842 1.00 54.81 C +ANISOU 4880 CA ILE B 239 9780 6223 4823 885 1627 1122 C +ATOM 4881 C ILE B 239 22.695 -11.581 69.584 1.00 54.32 C +ANISOU 4881 C ILE B 239 9748 6178 4712 1021 1469 1133 C +ATOM 4882 O ILE B 239 23.466 -11.860 70.480 1.00 55.68 O +ANISOU 4882 O ILE B 239 10053 6328 4776 1135 1436 1256 O +ATOM 4883 CB ILE B 239 20.877 -10.277 70.708 1.00 54.53 C +ANISOU 4883 CB ILE B 239 9741 6322 4655 902 1639 1133 C +ATOM 4884 CG1 ILE B 239 19.381 -10.015 70.642 1.00 55.23 C +ANISOU 4884 CG1 ILE B 239 9723 6408 4852 767 1791 1093 C +ATOM 4885 CG2 ILE B 239 21.597 -9.032 70.211 1.00 52.78 C +ANISOU 4885 CG2 ILE B 239 9411 6260 4382 962 1466 1044 C +ATOM 4886 CD1 ILE B 239 18.854 -9.174 71.770 1.00 56.37 C +ANISOU 4886 CD1 ILE B 239 9918 6613 4885 776 1901 1126 C +ATOM 4887 N THR B 240 23.092 -11.341 68.345 1.00 53.08 N +ANISOU 4887 N THR B 240 9462 6068 4638 1005 1369 1012 N +ATOM 4888 CA THR B 240 24.498 -11.343 67.977 1.00 52.67 C +ANISOU 4888 CA THR B 240 9405 6038 4568 1129 1234 1006 C +ATOM 4889 C THR B 240 24.896 -9.947 67.555 1.00 50.32 C +ANISOU 4889 C THR B 240 8981 5930 4207 1147 1092 919 C +ATOM 4890 O THR B 240 24.124 -9.245 66.905 1.00 49.00 O +ANISOU 4890 O THR B 240 8696 5842 4080 1044 1093 826 O +ATOM 4891 CB THR B 240 24.759 -12.307 66.819 1.00 53.71 C +ANISOU 4891 CB THR B 240 9510 6045 4850 1093 1266 926 C +ATOM 4892 OG1 THR B 240 24.426 -13.641 67.233 1.00 56.31 O +ANISOU 4892 OG1 THR B 240 9967 6168 5256 1077 1411 1009 O +ATOM 4893 CG2 THR B 240 26.216 -12.256 66.398 1.00 53.68 C +ANISOU 4893 CG2 THR B 240 9479 6064 4853 1226 1150 914 C +ATOM 4894 N GLY B 241 26.101 -9.553 67.931 1.00 50.07 N +ANISOU 4894 N GLY B 241 8969 5967 4089 1275 967 963 N +ATOM 4895 CA GLY B 241 26.559 -8.192 67.742 1.00 49.06 C +ANISOU 4895 CA GLY B 241 8743 6009 3889 1295 838 896 C +ATOM 4896 C GLY B 241 28.042 -8.166 67.489 1.00 49.32 C +ANISOU 4896 C GLY B 241 8743 6078 3917 1411 703 905 C +ATOM 4897 O GLY B 241 28.707 -9.173 67.629 1.00 49.62 O +ANISOU 4897 O GLY B 241 8838 6011 4003 1495 710 984 O +ATOM 4898 N PHE B 242 28.552 -6.990 67.138 1.00 49.51 N +ANISOU 4898 N PHE B 242 8666 6244 3900 1418 589 833 N +ATOM 4899 CA PHE B 242 29.953 -6.789 66.762 1.00 50.02 C +ANISOU 4899 CA PHE B 242 8661 6364 3980 1511 461 824 C +ATOM 4900 C PHE B 242 30.525 -5.530 67.398 1.00 49.56 C +ANISOU 4900 C PHE B 242 8579 6456 3795 1539 331 826 C +ATOM 4901 O PHE B 242 29.870 -4.502 67.451 1.00 48.06 O +ANISOU 4901 O PHE B 242 8364 6340 3553 1465 341 762 O +ATOM 4902 CB PHE B 242 30.065 -6.635 65.250 1.00 49.71 C +ANISOU 4902 CB PHE B 242 8497 6338 4051 1455 465 696 C +ATOM 4903 CG PHE B 242 29.435 -7.747 64.481 1.00 50.93 C +ANISOU 4903 CG PHE B 242 8677 6358 4316 1385 591 654 C +ATOM 4904 CD1 PHE B 242 28.090 -7.715 64.132 1.00 51.31 C +ANISOU 4904 CD1 PHE B 242 8718 6395 4383 1247 671 603 C +ATOM 4905 CD2 PHE B 242 30.191 -8.829 64.098 1.00 52.92 C +ANISOU 4905 CD2 PHE B 242 8951 6487 4667 1453 635 662 C +ATOM 4906 CE1 PHE B 242 27.508 -8.753 63.412 1.00 51.95 C +ANISOU 4906 CE1 PHE B 242 8824 6355 4558 1156 778 552 C +ATOM 4907 CE2 PHE B 242 29.626 -9.874 63.382 1.00 53.40 C +ANISOU 4907 CE2 PHE B 242 9053 6406 4828 1372 766 602 C +ATOM 4908 CZ PHE B 242 28.281 -9.837 63.037 1.00 53.27 C +ANISOU 4908 CZ PHE B 242 9040 6392 4809 1212 831 542 C +ATOM 4909 N GLN B 243 31.763 -5.612 67.863 1.00 51.05 N +ANISOU 4909 N GLN B 243 8765 6682 3948 1642 211 899 N +ATOM 4910 CA GLN B 243 32.470 -4.448 68.379 1.00 51.86 C +ANISOU 4910 CA GLN B 243 8835 6931 3937 1653 69 886 C +ATOM 4911 C GLN B 243 33.908 -4.461 67.923 1.00 51.96 C +ANISOU 4911 C GLN B 243 8727 6989 4025 1738 -55 897 C +ATOM 4912 O GLN B 243 34.479 -5.503 67.623 1.00 53.06 O +ANISOU 4912 O GLN B 243 8841 7037 4279 1825 -40 960 O +ATOM 4913 CB GLN B 243 32.455 -4.425 69.905 1.00 55.04 C +ANISOU 4913 CB GLN B 243 9386 7369 4156 1669 24 995 C +ATOM 4914 CG GLN B 243 31.098 -4.176 70.543 1.00 55.96 C +ANISOU 4914 CG GLN B 243 9624 7462 4175 1579 161 977 C +ATOM 4915 CD GLN B 243 31.200 -4.115 72.042 1.00 58.81 C +ANISOU 4915 CD GLN B 243 10152 7871 4322 1583 120 1075 C +ATOM 4916 OE1 GLN B 243 30.680 -4.968 72.750 1.00 60.58 O +ANISOU 4916 OE1 GLN B 243 10513 8016 4488 1589 207 1183 O +ATOM 4917 NE2 GLN B 243 31.916 -3.119 72.537 1.00 60.65 N +ANISOU 4917 NE2 GLN B 243 10383 8235 4423 1568 -15 1042 N +ATOM 4918 N ILE B 244 34.491 -3.277 67.894 1.00 51.94 N +ANISOU 4918 N ILE B 244 8646 7116 3972 1712 -166 834 N +ATOM 4919 CA ILE B 244 35.901 -3.112 67.581 1.00 52.82 C +ANISOU 4919 CA ILE B 244 8625 7294 4151 1781 -295 845 C +ATOM 4920 C ILE B 244 36.672 -2.482 68.714 1.00 54.31 C +ANISOU 4920 C ILE B 244 8832 7606 4197 1793 -469 908 C +ATOM 4921 O ILE B 244 37.878 -2.353 68.611 1.00 54.79 O +ANISOU 4921 O ILE B 244 8770 7733 4315 1847 -596 937 O +ATOM 4922 CB ILE B 244 36.136 -2.272 66.299 1.00 51.06 C +ANISOU 4922 CB ILE B 244 8258 7119 4021 1726 -283 708 C +ATOM 4923 CG1 ILE B 244 35.361 -0.968 66.337 1.00 49.36 C +ANISOU 4923 CG1 ILE B 244 8065 6972 3716 1613 -271 614 C +ATOM 4924 CG2 ILE B 244 35.764 -3.082 65.074 1.00 50.88 C +ANISOU 4924 CG2 ILE B 244 8204 6989 4138 1721 -144 656 C +ATOM 4925 CD1 ILE B 244 35.822 -0.005 65.278 1.00 48.83 C +ANISOU 4925 CD1 ILE B 244 7861 6970 3721 1566 -296 514 C +ATOM 4926 N VAL B 245 35.980 -2.085 69.779 1.00 56.60 N +ANISOU 4926 N VAL B 245 9272 7930 4304 1730 -468 922 N +ATOM 4927 CA VAL B 245 36.634 -1.602 71.001 1.00 59.28 C +ANISOU 4927 CA VAL B 245 9674 8388 4460 1717 -633 984 C +ATOM 4928 C VAL B 245 36.549 -2.700 72.035 1.00 62.92 C +ANISOU 4928 C VAL B 245 10276 8806 4823 1780 -651 1161 C +ATOM 4929 O VAL B 245 35.459 -3.128 72.372 1.00 62.03 O +ANISOU 4929 O VAL B 245 10306 8608 4654 1751 -506 1178 O +ATOM 4930 CB VAL B 245 35.947 -0.357 71.550 1.00 58.33 C +ANISOU 4930 CB VAL B 245 9654 8332 4176 1589 -601 868 C +ATOM 4931 CG1 VAL B 245 36.709 0.169 72.745 1.00 60.43 C +ANISOU 4931 CG1 VAL B 245 9992 8731 4236 1548 -779 906 C +ATOM 4932 CG2 VAL B 245 35.857 0.706 70.476 1.00 56.61 C +ANISOU 4932 CG2 VAL B 245 9305 8128 4074 1530 -557 712 C +ATOM 4933 N ASN B 246 37.703 -3.164 72.505 1.00 68.55 N +ANISOU 4933 N ASN B 246 10937 9574 5533 1866 -828 1304 N +ATOM 4934 CA ASN B 246 37.781 -4.251 73.478 1.00 73.38 C +ANISOU 4934 CA ASN B 246 11671 10146 6063 1943 -874 1514 C +ATOM 4935 C ASN B 246 38.054 -3.617 74.838 1.00 78.21 C +ANISOU 4935 C ASN B 246 12412 10918 6385 1863 -1043 1569 C +ATOM 4936 O ASN B 246 39.039 -2.899 74.999 1.00 78.03 O +ANISOU 4936 O ASN B 246 12288 11039 6319 1837 -1237 1551 O +ATOM 4937 CB ASN B 246 38.897 -5.216 73.071 1.00 75.09 C +ANISOU 4937 CB ASN B 246 11727 10310 6490 2102 -961 1659 C +ATOM 4938 CG ASN B 246 39.199 -6.264 74.132 1.00 78.98 C +ANISOU 4938 CG ASN B 246 12320 10776 6911 2198 -1055 1916 C +ATOM 4939 OD1 ASN B 246 38.310 -6.710 74.861 1.00 80.46 O +ANISOU 4939 OD1 ASN B 246 12713 10904 6951 2164 -965 1987 O +ATOM 4940 ND2 ASN B 246 40.468 -6.667 74.218 1.00 80.79 N +ANISOU 4940 ND2 ASN B 246 12394 11046 7255 2320 -1235 2072 N +ATOM 4941 N ASN B 247 37.202 -3.910 75.810 1.00 83.24 N +ANISOU 4941 N ASN B 247 13276 11530 6819 1813 -966 1634 N +ATOM 4942 CA ASN B 247 37.247 -3.226 77.109 1.00 88.47 C +ANISOU 4942 CA ASN B 247 14113 12343 7160 1699 -1081 1647 C +ATOM 4943 C ASN B 247 38.387 -3.714 77.992 1.00 91.77 C +ANISOU 4943 C ASN B 247 14533 12876 7460 1755 -1350 1872 C +ATOM 4944 O ASN B 247 38.821 -2.997 78.894 1.00 92.23 O +ANISOU 4944 O ASN B 247 14674 13103 7264 1648 -1522 1867 O +ATOM 4945 CB ASN B 247 35.938 -3.405 77.879 1.00 90.75 C +ANISOU 4945 CB ASN B 247 14654 12565 7260 1621 -884 1646 C +ATOM 4946 CG ASN B 247 34.719 -3.189 77.014 1.00 90.70 C +ANISOU 4946 CG ASN B 247 14624 12425 7410 1587 -617 1478 C +ATOM 4947 OD1 ASN B 247 34.797 -2.610 75.924 1.00 90.15 O +ANISOU 4947 OD1 ASN B 247 14378 12342 7529 1588 -590 1331 O +ATOM 4948 ND2 ASN B 247 33.577 -3.670 77.493 1.00 93.35 N +ANISOU 4948 ND2 ASN B 247 15131 12667 7670 1553 -420 1511 N +ATOM 4949 N GLU B 248 38.863 -4.931 77.728 1.00 93.95 N +ANISOU 4949 N GLU B 248 14716 13056 7923 1917 -1385 2070 N +ATOM 4950 CA GLU B 248 39.974 -5.501 78.480 1.00 98.03 C +ANISOU 4950 CA GLU B 248 15196 13667 8383 2001 -1648 2324 C +ATOM 4951 C GLU B 248 41.322 -4.909 78.030 1.00 97.35 C +ANISOU 4951 C GLU B 248 14844 13715 8429 2029 -1875 2297 C +ATOM 4952 O GLU B 248 42.321 -5.054 78.731 1.00100.80 O +ANISOU 4952 O GLU B 248 15223 14287 8788 2059 -2143 2484 O +ATOM 4953 CB GLU B 248 39.993 -7.038 78.349 1.00100.67 C +ANISOU 4953 CB GLU B 248 15517 13820 8913 2181 -1581 2558 C +ATOM 4954 CG GLU B 248 38.704 -7.752 78.773 1.00101.58 C +ANISOU 4954 CG GLU B 248 15882 13785 8929 2156 -1350 2607 C +ATOM 4955 CD GLU B 248 38.449 -7.715 80.278 1.00106.15 C +ANISOU 4955 CD GLU B 248 16725 14481 9126 2060 -1444 2752 C +ATOM 4956 OE1 GLU B 248 39.294 -8.238 81.053 1.00107.55 O +ANISOU 4956 OE1 GLU B 248 16912 14738 9214 2129 -1675 3015 O +ATOM 4957 OE2 GLU B 248 37.388 -7.180 80.692 1.00107.09 O +ANISOU 4957 OE2 GLU B 248 17045 14610 9034 1914 -1279 2612 O +ATOM 4958 N ASN B 249 41.353 -4.258 76.867 1.00 93.11 N +ANISOU 4958 N ASN B 249 14138 13144 8093 2013 -1774 2081 N +ATOM 4959 CA ASN B 249 42.564 -3.571 76.402 1.00 92.78 C +ANISOU 4959 CA ASN B 249 13846 13228 8175 2014 -1957 2028 C +ATOM 4960 C ASN B 249 42.950 -2.434 77.351 1.00 93.82 C +ANISOU 4960 C ASN B 249 14050 13580 8015 1840 -2171 1970 C +ATOM 4961 O ASN B 249 42.173 -1.498 77.526 1.00 89.56 O +ANISOU 4961 O ASN B 249 13664 13064 7298 1685 -2064 1773 O +ATOM 4962 CB ASN B 249 42.340 -3.010 74.985 1.00 88.94 C +ANISOU 4962 CB ASN B 249 13214 12659 7918 2002 -1772 1795 C +ATOM 4963 CG ASN B 249 43.555 -2.278 74.438 1.00 88.22 C +ANISOU 4963 CG ASN B 249 12865 12684 7968 1993 -1927 1732 C +ATOM 4964 OD1 ASN B 249 44.487 -1.939 75.161 1.00 90.79 O +ANISOU 4964 OD1 ASN B 249 13123 13175 8195 1957 -2181 1820 O +ATOM 4965 ND2 ASN B 249 43.571 -2.084 73.135 1.00 86.26 N +ANISOU 4965 ND2 ASN B 249 12466 12352 7956 2021 -1775 1591 N +ATOM 4966 N PRO B 250 44.161 -2.499 77.947 1.00 99.64 N +ANISOU 4966 N PRO B 250 14666 14476 8714 1860 -2472 2138 N +ATOM 4967 CA PRO B 250 44.544 -1.469 78.929 1.00102.39 C +ANISOU 4967 CA PRO B 250 15103 15045 8754 1667 -2695 2083 C +ATOM 4968 C PRO B 250 44.572 -0.040 78.358 1.00100.67 C +ANISOU 4968 C PRO B 250 14817 14878 8552 1513 -2646 1788 C +ATOM 4969 O PRO B 250 44.314 0.915 79.090 1.00101.26 O +ANISOU 4969 O PRO B 250 15067 15060 8346 1320 -2690 1653 O +ATOM 4970 CB PRO B 250 45.936 -1.921 79.411 1.00105.06 C +ANISOU 4970 CB PRO B 250 15247 15534 9136 1742 -3036 2337 C +ATOM 4971 CG PRO B 250 46.446 -2.841 78.363 1.00104.27 C +ANISOU 4971 CG PRO B 250 14879 15286 9451 1972 -2961 2449 C +ATOM 4972 CD PRO B 250 45.239 -3.487 77.740 1.00102.20 C +ANISOU 4972 CD PRO B 250 14756 14784 9289 2053 -2620 2382 C +ATOM 4973 N MET B 251 44.859 0.108 77.069 1.00 99.56 N +ANISOU 4973 N MET B 251 14443 14652 8733 1591 -2539 1688 N +ATOM 4974 CA MET B 251 44.806 1.429 76.421 1.00 98.61 C +ANISOU 4974 CA MET B 251 14262 14550 8653 1456 -2461 1425 C +ATOM 4975 C MET B 251 43.384 2.023 76.447 1.00 93.60 C +ANISOU 4975 C MET B 251 13874 13816 7872 1351 -2206 1232 C +ATOM 4976 O MET B 251 43.198 3.233 76.632 1.00 92.00 O +ANISOU 4976 O MET B 251 13747 13666 7542 1185 -2189 1041 O +ATOM 4977 CB MET B 251 45.321 1.341 74.985 1.00 99.91 C +ANISOU 4977 CB MET B 251 14147 14631 9183 1569 -2369 1379 C +ATOM 4978 CG MET B 251 45.517 2.698 74.325 1.00101.67 C +ANISOU 4978 CG MET B 251 14275 14891 9463 1433 -2332 1150 C +ATOM 4979 SD MET B 251 46.033 2.557 72.604 1.00105.58 S +ANISOU 4979 SD MET B 251 14476 15284 10354 1553 -2190 1099 S +ATOM 4980 CE MET B 251 47.618 1.713 72.797 1.00107.19 C +ANISOU 4980 CE MET B 251 14399 15586 10739 1691 -2440 1334 C +ATOM 4981 N VAL B 252 42.383 1.174 76.260 1.00 89.61 N +ANISOU 4981 N VAL B 252 13483 13159 7404 1447 -1999 1283 N +ATOM 4982 CA VAL B 252 41.000 1.627 76.346 1.00 86.05 C +ANISOU 4982 CA VAL B 252 13244 12614 6836 1361 -1758 1131 C +ATOM 4983 C VAL B 252 40.672 1.988 77.788 1.00 86.81 C +ANISOU 4983 C VAL B 252 13605 12808 6569 1220 -1820 1130 C +ATOM 4984 O VAL B 252 40.126 3.059 78.049 1.00 85.60 O +ANISOU 4984 O VAL B 252 13579 12664 6281 1073 -1723 938 O +ATOM 4985 CB VAL B 252 40.016 0.562 75.839 1.00 83.99 C +ANISOU 4985 CB VAL B 252 13031 12173 6706 1483 -1533 1197 C +ATOM 4986 CG1 VAL B 252 38.575 0.991 76.098 1.00 82.52 C +ANISOU 4986 CG1 VAL B 252 13054 11905 6392 1390 -1298 1067 C +ATOM 4987 CG2 VAL B 252 40.260 0.314 74.363 1.00 81.97 C +ANISOU 4987 CG2 VAL B 252 12544 11822 6776 1587 -1447 1157 C +ATOM 4988 N GLN B 253 41.024 1.091 78.713 1.00 88.04 N +ANISOU 4988 N GLN B 253 13848 13031 6570 1264 -1975 1348 N +ATOM 4989 CA GLN B 253 40.801 1.306 80.151 1.00 89.64 C +ANISOU 4989 CA GLN B 253 14324 13348 6385 1122 -2056 1376 C +ATOM 4990 C GLN B 253 41.393 2.630 80.646 1.00 88.27 C +ANISOU 4990 C GLN B 253 14178 13337 6021 923 -2213 1209 C +ATOM 4991 O GLN B 253 40.694 3.411 81.291 1.00 86.95 O +ANISOU 4991 O GLN B 253 14242 13178 5614 762 -2094 1044 O +ATOM 4992 CB GLN B 253 41.369 0.144 80.978 1.00 93.77 C +ANISOU 4992 CB GLN B 253 14890 13946 6790 1208 -2264 1679 C +ATOM 4993 CG GLN B 253 40.605 -1.165 80.830 1.00 94.81 C +ANISOU 4993 CG GLN B 253 15090 13904 7029 1364 -2082 1844 C +ATOM 4994 CD GLN B 253 41.138 -2.278 81.727 1.00100.56 C +ANISOU 4994 CD GLN B 253 15881 14693 7632 1447 -2283 2165 C +ATOM 4995 OE1 GLN B 253 42.292 -2.249 82.183 1.00105.79 O +ANISOU 4995 OE1 GLN B 253 16441 15525 8228 1442 -2595 2304 O +ATOM 4996 NE2 GLN B 253 40.294 -3.266 81.997 1.00102.46 N +ANISOU 4996 NE2 GLN B 253 16286 14797 7846 1520 -2111 2298 N +ATOM 4997 N GLN B 254 42.662 2.889 80.325 1.00 87.56 N +ANISOU 4997 N GLN B 254 13848 13365 6053 928 -2460 1241 N +ATOM 4998 CA GLN B 254 43.310 4.122 80.765 1.00 89.22 C +ANISOU 4998 CA GLN B 254 14066 13730 6101 723 -2627 1082 C +ATOM 4999 C GLN B 254 42.741 5.356 80.071 1.00 85.97 C +ANISOU 4999 C GLN B 254 13656 13215 5793 627 -2400 789 C +ATOM 5000 O GLN B 254 42.741 6.440 80.636 1.00 87.52 O +ANISOU 5000 O GLN B 254 13986 13477 5790 427 -2417 606 O +ATOM 5001 CB GLN B 254 44.837 4.058 80.592 1.00 91.58 C +ANISOU 5001 CB GLN B 254 14079 14185 6532 749 -2953 1204 C +ATOM 5002 CG GLN B 254 45.324 4.233 79.165 1.00 89.26 C +ANISOU 5002 CG GLN B 254 13466 13806 6641 859 -2888 1143 C +ATOM 5003 CD GLN B 254 46.830 4.139 79.019 1.00 91.93 C +ANISOU 5003 CD GLN B 254 13503 14293 7132 889 -3189 1270 C +ATOM 5004 OE1 GLN B 254 47.579 4.212 80.009 1.00 94.81 O +ANISOU 5004 OE1 GLN B 254 13884 14852 7285 784 -3485 1372 O +ATOM 5005 NE2 GLN B 254 47.291 3.999 77.767 1.00 89.87 N +ANISOU 5005 NE2 GLN B 254 12957 13947 7240 1023 -3114 1265 N +ATOM 5006 N PHE B 255 42.260 5.205 78.844 1.00 82.53 N +ANISOU 5006 N PHE B 255 13076 12614 5667 761 -2187 746 N +ATOM 5007 CA PHE B 255 41.589 6.315 78.187 1.00 79.31 C +ANISOU 5007 CA PHE B 255 12679 12094 5360 685 -1962 504 C +ATOM 5008 C PHE B 255 40.257 6.633 78.882 1.00 79.81 C +ANISOU 5008 C PHE B 255 13038 12070 5214 600 -1723 391 C +ATOM 5009 O PHE B 255 39.940 7.796 79.125 1.00 79.59 O +ANISOU 5009 O PHE B 255 13121 12022 5096 450 -1625 185 O +ATOM 5010 CB PHE B 255 41.356 6.026 76.713 1.00 74.65 C +ANISOU 5010 CB PHE B 255 11875 11363 5123 840 -1806 506 C +ATOM 5011 CG PHE B 255 40.588 7.104 76.026 1.00 71.54 C +ANISOU 5011 CG PHE B 255 11492 10851 4836 775 -1580 298 C +ATOM 5012 CD1 PHE B 255 41.243 8.216 75.544 1.00 70.84 C +ANISOU 5012 CD1 PHE B 255 11275 10794 4846 681 -1635 163 C +ATOM 5013 CD2 PHE B 255 39.209 7.028 75.903 1.00 69.04 C +ANISOU 5013 CD2 PHE B 255 11310 10392 4530 805 -1316 249 C +ATOM 5014 CE1 PHE B 255 40.552 9.230 74.927 1.00 68.53 C +ANISOU 5014 CE1 PHE B 255 10993 10382 4663 628 -1431 -5 C +ATOM 5015 CE2 PHE B 255 38.505 8.043 75.294 1.00 66.76 C +ANISOU 5015 CE2 PHE B 255 11013 9994 4357 755 -1122 83 C +ATOM 5016 CZ PHE B 255 39.185 9.144 74.795 1.00 66.94 C +ANISOU 5016 CZ PHE B 255 10913 10039 4480 672 -1180 -38 C +ATOM 5017 N ILE B 256 39.495 5.592 79.208 1.00 80.53 N +ANISOU 5017 N ILE B 256 13254 12099 5243 696 -1616 527 N +ATOM 5018 CA ILE B 256 38.183 5.754 79.833 1.00 81.47 C +ANISOU 5018 CA ILE B 256 13635 12126 5194 633 -1361 441 C +ATOM 5019 C ILE B 256 38.324 6.448 81.200 1.00 85.57 C +ANISOU 5019 C ILE B 256 14412 12767 5333 428 -1435 346 C +ATOM 5020 O ILE B 256 37.559 7.371 81.527 1.00 84.69 O +ANISOU 5020 O ILE B 256 14466 12585 5124 306 -1225 143 O +ATOM 5021 CB ILE B 256 37.460 4.392 80.011 1.00 81.58 C +ANISOU 5021 CB ILE B 256 13731 12064 5202 763 -1256 631 C +ATOM 5022 CG1 ILE B 256 37.199 3.698 78.660 1.00 79.65 C +ANISOU 5022 CG1 ILE B 256 13262 11684 5316 940 -1154 695 C +ATOM 5023 CG2 ILE B 256 36.146 4.581 80.768 1.00 81.98 C +ANISOU 5023 CG2 ILE B 256 14052 12033 5065 681 -988 544 C +ATOM 5024 CD1 ILE B 256 35.928 4.093 77.930 1.00 77.54 C +ANISOU 5024 CD1 ILE B 256 12988 11254 5217 950 -855 557 C +ATOM 5025 N GLN B 257 39.308 5.993 81.981 1.00 89.33 N +ANISOU 5025 N GLN B 257 14917 13421 5600 388 -1731 495 N +ATOM 5026 CA GLN B 257 39.608 6.556 83.295 1.00 93.74 C +ANISOU 5026 CA GLN B 257 15721 14134 5760 172 -1859 426 C +ATOM 5027 C GLN B 257 39.707 8.081 83.264 1.00 94.02 C +ANISOU 5027 C GLN B 257 15789 14164 5768 -15 -1802 133 C +ATOM 5028 O GLN B 257 39.101 8.771 84.095 1.00 96.89 O +ANISOU 5028 O GLN B 257 16426 14511 5873 -183 -1647 -40 O +ATOM 5029 CB GLN B 257 40.918 5.975 83.855 1.00 97.90 C +ANISOU 5029 CB GLN B 257 16173 14878 6144 160 -2259 641 C +ATOM 5030 CG GLN B 257 40.796 4.592 84.486 1.00100.78 C +ANISOU 5030 CG GLN B 257 16641 15279 6370 271 -2335 933 C +ATOM 5031 CD GLN B 257 42.035 4.186 85.291 1.00104.99 C +ANISOU 5031 CD GLN B 257 17146 16049 6694 220 -2746 1147 C +ATOM 5032 OE1 GLN B 257 43.148 4.652 85.026 1.00106.25 O +ANISOU 5032 OE1 GLN B 257 17090 16332 6947 176 -3000 1130 O +ATOM 5033 NE2 GLN B 257 41.846 3.305 86.274 1.00107.46 N +ANISOU 5033 NE2 GLN B 257 17669 16429 6731 225 -2817 1365 N +ATOM 5034 N ARG B 258 40.460 8.598 82.297 1.00 91.65 N +ANISOU 5034 N ARG B 258 15215 13864 5743 13 -1903 78 N +ATOM 5035 CA ARG B 258 40.677 10.037 82.146 1.00 90.80 C +ANISOU 5035 CA ARG B 258 15103 13735 5659 -156 -1861 -182 C +ATOM 5036 C ARG B 258 39.432 10.706 81.568 1.00 86.03 C +ANISOU 5036 C ARG B 258 14554 12903 5230 -126 -1481 -363 C +ATOM 5037 O ARG B 258 39.026 11.782 82.011 1.00 86.06 O +ANISOU 5037 O ARG B 258 14734 12845 5119 -288 -1324 -589 O +ATOM 5038 CB ARG B 258 41.886 10.299 81.238 1.00 91.15 C +ANISOU 5038 CB ARG B 258 14821 13846 5966 -125 -2080 -157 C +ATOM 5039 CG ARG B 258 43.147 9.534 81.640 1.00 95.18 C +ANISOU 5039 CG ARG B 258 15199 14571 6391 -111 -2460 60 C +ATOM 5040 CD ARG B 258 44.351 9.807 80.756 1.00 95.99 C +ANISOU 5040 CD ARG B 258 14961 14737 6773 -84 -2654 81 C +ATOM 5041 NE ARG B 258 44.943 11.112 81.081 1.00 99.97 N +ANISOU 5041 NE ARG B 258 15491 15317 7174 -331 -2752 -132 N +ATOM 5042 CZ ARG B 258 46.138 11.537 80.679 1.00101.60 C +ANISOU 5042 CZ ARG B 258 15443 15627 7530 -392 -2971 -138 C +ATOM 5043 NH1 ARG B 258 46.912 10.764 79.918 1.00102.07 N +ANISOU 5043 NH1 ARG B 258 15190 15730 7859 -213 -3110 60 N +ATOM 5044 NH2 ARG B 258 46.555 12.749 81.035 1.00102.31 N +ANISOU 5044 NH2 ARG B 258 15593 15768 7512 -640 -3033 -353 N +ATOM 5045 N TRP B 259 38.836 10.040 80.584 1.00 81.36 N +ANISOU 5045 N TRP B 259 13807 12184 4921 79 -1336 -255 N +ATOM 5046 CA TRP B 259 37.687 10.543 79.833 1.00 77.41 C +ANISOU 5046 CA TRP B 259 13288 11477 4647 140 -1011 -373 C +ATOM 5047 C TRP B 259 36.519 10.921 80.736 1.00 78.30 C +ANISOU 5047 C TRP B 259 13690 11496 4562 49 -738 -502 C +ATOM 5048 O TRP B 259 35.964 12.021 80.616 1.00 77.95 O +ANISOU 5048 O TRP B 259 13698 11324 4595 -23 -524 -700 O +ATOM 5049 CB TRP B 259 37.275 9.465 78.812 1.00 73.70 C +ANISOU 5049 CB TRP B 259 12632 10929 4442 360 -951 -196 C +ATOM 5050 CG TRP B 259 36.029 9.709 78.004 1.00 70.12 C +ANISOU 5050 CG TRP B 259 12135 10284 4221 441 -650 -259 C +ATOM 5051 CD1 TRP B 259 34.870 9.006 78.082 1.00 68.94 C +ANISOU 5051 CD1 TRP B 259 12066 10038 4089 524 -447 -192 C +ATOM 5052 CD2 TRP B 259 35.835 10.689 76.973 1.00 68.22 C +ANISOU 5052 CD2 TRP B 259 11743 9934 4242 447 -536 -377 C +ATOM 5053 NE1 TRP B 259 33.964 9.485 77.173 1.00 67.44 N +ANISOU 5053 NE1 TRP B 259 11771 9697 4156 579 -229 -260 N +ATOM 5054 CE2 TRP B 259 34.525 10.525 76.485 1.00 66.56 C +ANISOU 5054 CE2 TRP B 259 11524 9574 4192 537 -280 -367 C +ATOM 5055 CE3 TRP B 259 36.640 11.693 76.421 1.00 68.41 C +ANISOU 5055 CE3 TRP B 259 11636 9972 4382 379 -628 -480 C +ATOM 5056 CZ2 TRP B 259 33.995 11.319 75.465 1.00 64.71 C +ANISOU 5056 CZ2 TRP B 259 11151 9211 4224 569 -130 -439 C +ATOM 5057 CZ3 TRP B 259 36.110 12.485 75.395 1.00 66.60 C +ANISOU 5057 CZ3 TRP B 259 11285 9602 4418 412 -459 -554 C +ATOM 5058 CH2 TRP B 259 34.801 12.293 74.936 1.00 64.58 C +ANISOU 5058 CH2 TRP B 259 11023 9206 4308 509 -222 -526 C +ATOM 5059 N VAL B 260 36.161 10.027 81.651 1.00 79.37 N +ANISOU 5059 N VAL B 260 14016 11688 4450 53 -733 -387 N +ATOM 5060 CA VAL B 260 34.982 10.245 82.491 1.00 81.72 C +ANISOU 5060 CA VAL B 260 14588 11891 4569 -19 -438 -493 C +ATOM 5061 C VAL B 260 35.171 11.326 83.586 1.00 85.66 C +ANISOU 5061 C VAL B 260 15350 12439 4755 -261 -410 -717 C +ATOM 5062 O VAL B 260 34.204 11.748 84.218 1.00 86.48 O +ANISOU 5062 O VAL B 260 15679 12438 4739 -338 -118 -857 O +ATOM 5063 CB VAL B 260 34.469 8.914 83.106 1.00 82.88 C +ANISOU 5063 CB VAL B 260 14868 12068 4552 56 -408 -291 C +ATOM 5064 CG1 VAL B 260 34.189 7.904 81.999 1.00 79.33 C +ANISOU 5064 CG1 VAL B 260 14175 11539 4425 275 -395 -106 C +ATOM 5065 CG2 VAL B 260 35.434 8.350 84.164 1.00 85.60 C +ANISOU 5065 CG2 VAL B 260 15360 12629 4535 -36 -711 -159 C +ATOM 5066 N ARG B 261 36.411 11.770 83.799 1.00 88.25 N +ANISOU 5066 N ARG B 261 15647 12922 4962 -390 -703 -757 N +ATOM 5067 CA ARG B 261 36.704 12.837 84.758 1.00 92.97 C +ANISOU 5067 CA ARG B 261 16484 13571 5267 -647 -704 -990 C +ATOM 5068 C ARG B 261 36.615 14.243 84.158 1.00 92.19 C +ANISOU 5068 C ARG B 261 16313 13315 5397 -717 -537 -1241 C +ATOM 5069 O ARG B 261 36.754 15.230 84.880 1.00 94.85 O +ANISOU 5069 O ARG B 261 16856 13649 5532 -936 -482 -1471 O +ATOM 5070 CB ARG B 261 38.099 12.618 85.365 1.00 96.09 C +ANISOU 5070 CB ARG B 261 16883 14228 5398 -780 -1127 -905 C +ATOM 5071 CG ARG B 261 38.192 11.302 86.129 1.00 98.07 C +ANISOU 5071 CG ARG B 261 17245 14632 5382 -731 -1294 -648 C +ATOM 5072 CD ARG B 261 39.510 11.083 86.843 1.00101.67 C +ANISOU 5072 CD ARG B 261 17715 15359 5556 -868 -1723 -539 C +ATOM 5073 NE ARG B 261 40.610 10.755 85.932 1.00100.09 N +ANISOU 5073 NE ARG B 261 17145 15238 5644 -742 -2018 -381 N +ATOM 5074 CZ ARG B 261 41.670 10.009 86.260 1.00102.37 C +ANISOU 5074 CZ ARG B 261 17330 15740 5824 -729 -2397 -148 C +ATOM 5075 NH1 ARG B 261 42.610 9.781 85.350 1.00101.37 N +ANISOU 5075 NH1 ARG B 261 16848 15656 6009 -604 -2609 -27 N +ATOM 5076 NH2 ARG B 261 41.793 9.465 87.473 1.00105.16 N +ANISOU 5076 NH2 ARG B 261 17923 16262 5770 -834 -2559 -21 N +ATOM 5077 N LEU B 262 36.390 14.338 82.850 1.00 88.87 N +ANISOU 5077 N LEU B 262 15614 12760 5390 -541 -454 -1196 N +ATOM 5078 CA LEU B 262 36.428 15.626 82.153 1.00 87.40 C +ANISOU 5078 CA LEU B 262 15324 12427 5456 -589 -333 -1386 C +ATOM 5079 C LEU B 262 35.175 16.465 82.392 1.00 88.21 C +ANISOU 5079 C LEU B 262 15599 12301 5615 -620 77 -1582 C +ATOM 5080 O LEU B 262 34.063 15.934 82.421 1.00 87.62 O +ANISOU 5080 O LEU B 262 15570 12128 5592 -498 309 -1514 O +ATOM 5081 CB LEU B 262 36.624 15.395 80.653 1.00 83.02 C +ANISOU 5081 CB LEU B 262 14419 11820 5302 -394 -394 -1247 C +ATOM 5082 CG LEU B 262 37.933 14.704 80.271 1.00 81.89 C +ANISOU 5082 CG LEU B 262 14067 11874 5174 -355 -765 -1075 C +ATOM 5083 CD1 LEU B 262 37.910 14.280 78.814 1.00 78.65 C +ANISOU 5083 CD1 LEU B 262 13351 11397 5133 -148 -763 -931 C +ATOM 5084 CD2 LEU B 262 39.129 15.601 80.538 1.00 83.55 C +ANISOU 5084 CD2 LEU B 262 14261 12189 5294 -556 -979 -1208 C +ATOM 5085 N ASP B 263 35.371 17.773 82.547 1.00 90.44 N +ANISOU 5085 N ASP B 263 15964 12487 5910 -783 173 -1822 N +ATOM 5086 CA ASP B 263 34.288 18.714 82.866 1.00 92.55 C +ANISOU 5086 CA ASP B 263 16408 12518 6238 -831 578 -2036 C +ATOM 5087 C ASP B 263 33.152 18.717 81.827 1.00 89.30 C +ANISOU 5087 C ASP B 263 15798 11892 6238 -601 847 -1950 C +ATOM 5088 O ASP B 263 33.420 18.741 80.628 1.00 84.80 O +ANISOU 5088 O ASP B 263 14946 11297 5976 -474 744 -1836 O +ATOM 5089 CB ASP B 263 34.875 20.122 82.983 1.00 95.91 C +ANISOU 5089 CB ASP B 263 16902 12861 6676 -1033 601 -2292 C +ATOM 5090 CG ASP B 263 33.810 21.194 83.166 1.00 98.92 C +ANISOU 5090 CG ASP B 263 17430 12955 7198 -1062 1040 -2514 C +ATOM 5091 OD1 ASP B 263 33.175 21.227 84.245 1.00103.41 O +ANISOU 5091 OD1 ASP B 263 18294 13485 7508 -1163 1262 -2648 O +ATOM 5092 OD2 ASP B 263 33.617 22.014 82.234 1.00 98.77 O +ANISOU 5092 OD2 ASP B 263 17234 12741 7551 -983 1172 -2549 O +ATOM 5093 N GLU B 264 31.897 18.722 82.300 1.00 90.36 N +ANISOU 5093 N GLU B 264 16080 11878 6372 -561 1193 -2005 N +ATOM 5094 CA GLU B 264 30.705 18.706 81.420 1.00 88.47 C +ANISOU 5094 CA GLU B 264 15652 11444 6517 -353 1455 -1915 C +ATOM 5095 C GLU B 264 30.618 19.896 80.426 1.00 87.72 C +ANISOU 5095 C GLU B 264 15371 11149 6808 -307 1569 -1988 C +ATOM 5096 O GLU B 264 30.212 19.711 79.264 1.00 84.35 O +ANISOU 5096 O GLU B 264 14677 10658 6714 -126 1573 -1826 O +ATOM 5097 CB GLU B 264 29.415 18.612 82.253 1.00 89.51 C +ANISOU 5097 CB GLU B 264 15985 11449 6573 -346 1827 -1986 C +ATOM 5098 N ARG B 265 30.991 21.098 80.878 1.00 89.98 N +ANISOU 5098 N ARG B 265 15807 11335 7043 -478 1661 -2227 N +ATOM 5099 CA ARG B 265 31.029 22.281 80.002 1.00 89.33 C +ANISOU 5099 CA ARG B 265 15572 11055 7314 -454 1760 -2296 C +ATOM 5100 C ARG B 265 32.098 22.151 78.901 1.00 86.93 C +ANISOU 5100 C ARG B 265 15005 10876 7147 -413 1420 -2152 C +ATOM 5101 O ARG B 265 31.782 22.192 77.714 1.00 84.03 O +ANISOU 5101 O ARG B 265 14386 10428 7114 -249 1433 -2002 O +ATOM 5102 CB ARG B 265 31.259 23.561 80.823 1.00 92.41 C +ANISOU 5102 CB ARG B 265 16211 11303 7595 -673 1938 -2602 C +ATOM 5103 N GLU B 266 33.354 21.968 79.302 1.00 87.83 N +ANISOU 5103 N GLU B 266 15176 11196 6998 -567 1115 -2188 N +ATOM 5104 CA GLU B 266 34.480 21.917 78.357 1.00 85.39 C +ANISOU 5104 CA GLU B 266 14627 11006 6811 -553 809 -2078 C +ATOM 5105 C GLU B 266 34.460 20.702 77.415 1.00 80.14 C +ANISOU 5105 C GLU B 266 13715 10466 6269 -345 637 -1800 C +ATOM 5106 O GLU B 266 34.924 20.801 76.279 1.00 78.76 O +ANISOU 5106 O GLU B 266 13301 10295 6326 -270 520 -1696 O +ATOM 5107 CB GLU B 266 35.811 21.963 79.127 1.00 89.33 C +ANISOU 5107 CB GLU B 266 15237 11707 6994 -775 521 -2180 C +ATOM 5108 CG GLU B 266 37.030 22.365 78.301 1.00 89.91 C +ANISOU 5108 CG GLU B 266 15092 11851 7218 -825 274 -2150 C +ATOM 5109 CD GLU B 266 38.210 22.832 79.164 1.00 93.94 C +ANISOU 5109 CD GLU B 266 15733 12501 7456 -1096 59 -2319 C +ATOM 5110 OE1 GLU B 266 38.016 23.721 80.038 1.00 95.78 O +ANISOU 5110 OE1 GLU B 266 16221 12626 7542 -1289 226 -2567 O +ATOM 5111 OE2 GLU B 266 39.342 22.318 78.959 1.00 94.59 O +ANISOU 5111 OE2 GLU B 266 15658 12801 7481 -1124 -274 -2208 O +ATOM 5112 N PHE B 267 33.930 19.569 77.877 1.00 77.13 N +ANISOU 5112 N PHE B 267 13401 10177 5728 -263 638 -1688 N +ATOM 5113 CA PHE B 267 33.896 18.320 77.100 1.00 72.25 C +ANISOU 5113 CA PHE B 267 12582 9668 5198 -82 488 -1442 C +ATOM 5114 C PHE B 267 32.552 17.580 77.226 1.00 71.85 C +ANISOU 5114 C PHE B 267 12572 9545 5183 51 704 -1350 C +ATOM 5115 O PHE B 267 32.507 16.491 77.796 1.00 72.02 O +ANISOU 5115 O PHE B 267 12676 9690 4997 74 624 -1254 O +ATOM 5116 CB PHE B 267 34.997 17.366 77.572 1.00 70.74 C +ANISOU 5116 CB PHE B 267 12407 9725 4744 -131 163 -1352 C +ATOM 5117 CG PHE B 267 36.392 17.892 77.412 1.00 70.70 C +ANISOU 5117 CG PHE B 267 12316 9828 4717 -255 -89 -1407 C +ATOM 5118 CD1 PHE B 267 36.975 18.628 78.422 1.00 72.83 C +ANISOU 5118 CD1 PHE B 267 12780 10144 4748 -476 -143 -1595 C +ATOM 5119 CD2 PHE B 267 37.144 17.616 76.259 1.00 68.68 C +ANISOU 5119 CD2 PHE B 267 11786 9637 4672 -163 -271 -1272 C +ATOM 5120 CE1 PHE B 267 38.269 19.102 78.300 1.00 73.39 C +ANISOU 5120 CE1 PHE B 267 12756 10323 4805 -608 -386 -1644 C +ATOM 5121 CE2 PHE B 267 38.436 18.089 76.129 1.00 69.08 C +ANISOU 5121 CE2 PHE B 267 11740 9788 4717 -282 -492 -1319 C +ATOM 5122 CZ PHE B 267 39.001 18.835 77.158 1.00 71.78 C +ANISOU 5122 CZ PHE B 267 12260 10177 4834 -506 -557 -1502 C +ATOM 5123 N PRO B 268 31.453 18.149 76.677 1.00 72.00 N +ANISOU 5123 N PRO B 268 12515 9360 5480 142 974 -1362 N +ATOM 5124 CA PRO B 268 30.121 17.519 76.836 1.00 71.90 C +ANISOU 5124 CA PRO B 268 12523 9271 5522 254 1197 -1284 C +ATOM 5125 C PRO B 268 30.053 16.062 76.371 1.00 70.46 C +ANISOU 5125 C PRO B 268 12217 9221 5331 378 1040 -1066 C +ATOM 5126 O PRO B 268 30.870 15.639 75.566 1.00 70.36 O +ANISOU 5126 O PRO B 268 12040 9317 5374 421 797 -958 O +ATOM 5127 CB PRO B 268 29.193 18.412 75.992 1.00 71.02 C +ANISOU 5127 CB PRO B 268 12258 8942 5784 347 1432 -1286 C +ATOM 5128 CG PRO B 268 30.083 19.241 75.132 1.00 69.98 C +ANISOU 5128 CG PRO B 268 11988 8796 5804 318 1287 -1305 C +ATOM 5129 CD PRO B 268 31.391 19.375 75.856 1.00 71.39 C +ANISOU 5129 CD PRO B 268 12312 9114 5697 149 1079 -1425 C +ATOM 5130 N GLU B 269 29.094 15.309 76.904 1.00 72.46 N +ANISOU 5130 N GLU B 269 12557 9454 5516 426 1197 -1012 N +ATOM 5131 CA GLU B 269 28.857 13.893 76.548 1.00 72.34 C +ANISOU 5131 CA GLU B 269 12450 9531 5504 535 1098 -815 C +ATOM 5132 C GLU B 269 29.993 12.906 76.900 1.00 72.20 C +ANISOU 5132 C GLU B 269 12487 9711 5234 507 802 -727 C +ATOM 5133 O GLU B 269 30.019 11.789 76.382 1.00 71.39 O +ANISOU 5133 O GLU B 269 12273 9670 5180 606 691 -563 O +ATOM 5134 CB GLU B 269 28.443 13.745 75.063 1.00 71.13 C +ANISOU 5134 CB GLU B 269 12012 9326 5689 668 1078 -685 C +ATOM 5135 CG GLU B 269 27.173 14.519 74.695 1.00 72.23 C +ANISOU 5135 CG GLU B 269 12062 9277 6102 722 1357 -712 C +ATOM 5136 CD GLU B 269 26.459 14.012 73.428 1.00 71.31 C +ANISOU 5136 CD GLU B 269 11693 9137 6264 846 1346 -544 C +ATOM 5137 OE1 GLU B 269 27.012 13.185 72.655 1.00 72.42 O +ANISOU 5137 OE1 GLU B 269 11718 9391 6405 886 1129 -428 O +ATOM 5138 OE2 GLU B 269 25.328 14.479 73.163 1.00 70.57 O +ANISOU 5138 OE2 GLU B 269 11505 8907 6401 899 1558 -530 O +ATOM 5139 N ALA B 270 30.905 13.306 77.783 1.00 74.49 N +ANISOU 5139 N ALA B 270 12945 10093 5263 372 680 -832 N +ATOM 5140 CA ALA B 270 31.940 12.403 78.310 1.00 76.11 C +ANISOU 5140 CA ALA B 270 13214 10490 5213 339 402 -735 C +ATOM 5141 C ALA B 270 31.562 11.782 79.689 1.00 80.00 C +ANISOU 5141 C ALA B 270 13985 11036 5376 272 473 -723 C +ATOM 5142 O ALA B 270 31.919 10.629 79.972 1.00 81.11 O +ANISOU 5142 O ALA B 270 14150 11293 5376 315 311 -559 O +ATOM 5143 CB ALA B 270 33.288 13.122 78.380 1.00 76.04 C +ANISOU 5143 CB ALA B 270 13188 10585 5117 223 167 -823 C +ATOM 5144 N LYS B 271 30.858 12.531 80.542 1.00 82.40 N +ANISOU 5144 N LYS B 271 14502 11249 5557 166 726 -891 N +ATOM 5145 CA LYS B 271 30.332 11.969 81.796 1.00 86.06 C +ANISOU 5145 CA LYS B 271 15240 11745 5714 99 851 -883 C +ATOM 5146 C LYS B 271 28.970 11.295 81.608 1.00 85.57 C +ANISOU 5146 C LYS B 271 15142 11559 5810 220 1119 -789 C +ATOM 5147 O LYS B 271 28.790 10.131 81.970 1.00 86.39 O +ANISOU 5147 O LYS B 271 15310 11726 5788 263 1083 -630 O +ATOM 5148 CB LYS B 271 30.234 13.036 82.911 1.00 89.98 C +ANISOU 5148 CB LYS B 271 16020 12207 5961 -94 1020 -1125 C +ATOM 5149 CG LYS B 271 31.451 13.071 83.825 1.00 92.47 C +ANISOU 5149 CG LYS B 271 16520 12723 5889 -270 737 -1162 C +ATOM 5150 CD LYS B 271 31.230 13.940 85.058 1.00 96.68 C +ANISOU 5150 CD LYS B 271 17390 13231 6112 -486 929 -1403 C +ATOM 5151 CE LYS B 271 31.395 15.423 84.758 1.00 97.12 C +ANISOU 5151 CE LYS B 271 17420 13157 6323 -580 1037 -1652 C +ATOM 5152 NZ LYS B 271 31.382 16.203 86.030 1.00100.17 N +ANISOU 5152 NZ LYS B 271 18163 13540 6356 -824 1185 -1902 N +ATOM 5153 N ASN B 272 28.020 12.039 81.052 1.00 84.70 N +ANISOU 5153 N ASN B 272 14923 11269 5989 272 1385 -879 N +ATOM 5154 CA ASN B 272 26.625 11.579 80.935 1.00 84.01 C +ANISOU 5154 CA ASN B 272 14790 11054 6075 366 1671 -814 C +ATOM 5155 C ASN B 272 26.343 10.446 79.922 1.00 79.47 C +ANISOU 5155 C ASN B 272 13976 10492 5724 518 1569 -599 C +ATOM 5156 O ASN B 272 25.306 9.778 80.033 1.00 80.56 O +ANISOU 5156 O ASN B 272 14111 10565 5930 568 1761 -520 O +ATOM 5157 CB ASN B 272 25.698 12.778 80.643 1.00 86.01 C +ANISOU 5157 CB ASN B 272 14972 11106 6600 380 1981 -963 C +ATOM 5158 CG ASN B 272 26.021 13.471 79.324 1.00 84.84 C +ANISOU 5158 CG ASN B 272 14548 10906 6779 458 1864 -955 C +ATOM 5159 OD1 ASN B 272 27.003 14.220 79.219 1.00 85.13 O +ANISOU 5159 OD1 ASN B 272 14597 10983 6766 386 1705 -1050 O +ATOM 5160 ND2 ASN B 272 25.185 13.237 78.314 1.00 83.36 N +ANISOU 5160 ND2 ASN B 272 14114 10634 6923 591 1941 -838 N +ATOM 5161 N ALA B 273 27.234 10.217 78.958 1.00 74.46 N +ANISOU 5161 N ALA B 273 13150 9938 5202 578 1289 -513 N +ATOM 5162 CA ALA B 273 26.917 9.264 77.852 1.00 70.50 C +ANISOU 5162 CA ALA B 273 12418 9427 4941 710 1221 -342 C +ATOM 5163 C ALA B 273 27.979 8.175 77.617 1.00 66.59 C +ANISOU 5163 C ALA B 273 11885 9069 4346 751 921 -195 C +ATOM 5164 O ALA B 273 29.166 8.429 77.743 1.00 67.02 O +ANISOU 5164 O ALA B 273 11959 9230 4273 708 699 -219 O +ATOM 5165 CB ALA B 273 26.644 10.022 76.552 1.00 68.33 C +ANISOU 5165 CB ALA B 273 11888 9066 5008 775 1244 -366 C +ATOM 5166 N PRO B 274 27.547 6.957 77.278 1.00 63.12 N +ANISOU 5166 N PRO B 274 11381 8618 3982 832 925 -43 N +ATOM 5167 CA PRO B 274 28.534 5.906 77.012 1.00 62.16 C +ANISOU 5167 CA PRO B 274 11214 8596 3806 887 669 98 C +ATOM 5168 C PRO B 274 29.400 6.196 75.772 1.00 59.56 C +ANISOU 5168 C PRO B 274 10657 8304 3668 938 476 95 C +ATOM 5169 O PRO B 274 28.972 6.880 74.849 1.00 57.79 O +ANISOU 5169 O PRO B 274 10276 8012 3667 956 551 34 O +ATOM 5170 CB PRO B 274 27.684 4.647 76.800 1.00 61.52 C +ANISOU 5170 CB PRO B 274 11107 8449 3818 955 775 234 C +ATOM 5171 CG PRO B 274 26.315 5.129 76.456 1.00 61.35 C +ANISOU 5171 CG PRO B 274 11009 8304 3996 952 1038 169 C +ATOM 5172 CD PRO B 274 26.163 6.517 77.029 1.00 62.52 C +ANISOU 5172 CD PRO B 274 11246 8426 4080 876 1163 3 C +ATOM 5173 N LEU B 275 30.615 5.678 75.778 1.00 59.06 N +ANISOU 5173 N LEU B 275 10574 8348 3518 961 233 172 N +ATOM 5174 CA LEU B 275 31.568 5.979 74.748 1.00 58.31 C +ANISOU 5174 CA LEU B 275 10283 8299 3573 995 59 162 C +ATOM 5175 C LEU B 275 31.157 5.303 73.442 1.00 57.21 C +ANISOU 5175 C LEU B 275 9957 8093 3687 1089 95 234 C +ATOM 5176 O LEU B 275 31.119 4.069 73.371 1.00 58.24 O +ANISOU 5176 O LEU B 275 10088 8211 3826 1154 73 355 O +ATOM 5177 CB LEU B 275 32.950 5.478 75.151 1.00 59.11 C +ANISOU 5177 CB LEU B 275 10395 8530 3534 1005 -198 245 C +ATOM 5178 CG LEU B 275 34.039 5.842 74.139 1.00 58.46 C +ANISOU 5178 CG LEU B 275 10101 8501 3610 1032 -368 228 C +ATOM 5179 CD1 LEU B 275 34.311 7.347 74.188 1.00 58.86 C +ANISOU 5179 CD1 LEU B 275 10148 8569 3647 925 -370 64 C +ATOM 5180 CD2 LEU B 275 35.312 5.039 74.384 1.00 59.62 C +ANISOU 5180 CD2 LEU B 275 10204 8758 3688 1081 -608 355 C +ATOM 5181 N LYS B 276 30.873 6.102 72.415 1.00 54.96 N +ANISOU 5181 N LYS B 276 9520 7763 3597 1086 146 162 N +ATOM 5182 CA LYS B 276 30.486 5.559 71.121 1.00 53.43 C +ANISOU 5182 CA LYS B 276 9158 7523 3617 1147 169 217 C +ATOM 5183 C LYS B 276 31.746 5.091 70.415 1.00 50.95 C +ANISOU 5183 C LYS B 276 8732 7282 3345 1193 -20 263 C +ATOM 5184 O LYS B 276 32.836 5.647 70.634 1.00 50.84 O +ANISOU 5184 O LYS B 276 8704 7346 3265 1170 -160 227 O +ATOM 5185 CB LYS B 276 29.732 6.597 70.264 1.00 54.35 C +ANISOU 5185 CB LYS B 276 9153 7577 3917 1124 277 149 C +ATOM 5186 CG LYS B 276 28.586 7.297 70.999 1.00 56.86 C +ANISOU 5186 CG LYS B 276 9561 7813 4229 1084 481 88 C +ATOM 5187 CD LYS B 276 27.848 8.326 70.155 1.00 57.31 C +ANISOU 5187 CD LYS B 276 9477 7797 4501 1080 582 51 C +ATOM 5188 CE LYS B 276 26.997 7.630 69.108 1.00 58.10 C +ANISOU 5188 CE LYS B 276 9428 7868 4776 1117 615 143 C +ATOM 5189 NZ LYS B 276 25.998 8.520 68.449 1.00 59.34 N +ANISOU 5189 NZ LYS B 276 9449 7951 5143 1116 728 144 N +ATOM 5190 N TYR B 277 31.602 4.052 69.592 1.00 48.15 N +ANISOU 5190 N TYR B 277 8295 6895 3104 1251 -16 337 N +ATOM 5191 CA TYR B 277 32.738 3.502 68.874 1.00 46.67 C +ANISOU 5191 CA TYR B 277 7999 6754 2980 1305 -154 377 C +ATOM 5192 C TYR B 277 33.324 4.547 67.896 1.00 44.13 C +ANISOU 5192 C TYR B 277 7532 6473 2761 1274 -211 300 C +ATOM 5193 O TYR B 277 34.509 4.493 67.562 1.00 43.33 O +ANISOU 5193 O TYR B 277 7344 6432 2684 1299 -335 308 O +ATOM 5194 CB TYR B 277 32.354 2.201 68.154 1.00 47.14 C +ANISOU 5194 CB TYR B 277 8021 6744 3143 1357 -97 446 C +ATOM 5195 CG TYR B 277 31.656 2.408 66.818 1.00 46.72 C +ANISOU 5195 CG TYR B 277 7851 6655 3245 1323 -20 401 C +ATOM 5196 CD1 TYR B 277 30.277 2.610 66.750 1.00 46.72 C +ANISOU 5196 CD1 TYR B 277 7863 6599 3289 1276 111 389 C +ATOM 5197 CD2 TYR B 277 32.374 2.412 65.634 1.00 46.82 C +ANISOU 5197 CD2 TYR B 277 7735 6696 3355 1331 -80 378 C +ATOM 5198 CE1 TYR B 277 29.628 2.795 65.552 1.00 46.06 C +ANISOU 5198 CE1 TYR B 277 7664 6500 3335 1235 152 370 C +ATOM 5199 CE2 TYR B 277 31.738 2.596 64.420 1.00 46.74 C +ANISOU 5199 CE2 TYR B 277 7636 6670 3452 1283 -25 347 C +ATOM 5200 CZ TYR B 277 30.363 2.794 64.387 1.00 46.90 C +ANISOU 5200 CZ TYR B 277 7666 6646 3506 1234 76 350 C +ATOM 5201 OH TYR B 277 29.741 2.990 63.174 1.00 46.66 O +ANISOU 5201 OH TYR B 277 7536 6619 3573 1177 100 339 O +ATOM 5202 N THR B 278 32.508 5.498 67.448 1.00 42.09 N +ANISOU 5202 N THR B 278 7238 6177 2575 1223 -116 238 N +ATOM 5203 CA THR B 278 33.020 6.581 66.595 1.00 41.39 C +ANISOU 5203 CA THR B 278 7029 6116 2577 1186 -160 180 C +ATOM 5204 C THR B 278 33.883 7.613 67.340 1.00 41.96 C +ANISOU 5204 C THR B 278 7138 6239 2563 1137 -242 110 C +ATOM 5205 O THR B 278 34.720 8.277 66.715 1.00 42.06 O +ANISOU 5205 O THR B 278 7047 6291 2641 1111 -316 75 O +ATOM 5206 CB THR B 278 31.908 7.274 65.785 1.00 40.06 C +ANISOU 5206 CB THR B 278 6796 5887 2537 1154 -46 165 C +ATOM 5207 OG1 THR B 278 30.745 7.462 66.600 1.00 40.91 O +ANISOU 5207 OG1 THR B 278 6995 5927 2620 1143 84 157 O +ATOM 5208 CG2 THR B 278 31.549 6.399 64.597 1.00 39.22 C +ANISOU 5208 CG2 THR B 278 6600 5774 2525 1172 -34 220 C +ATOM 5209 N SER B 279 33.697 7.743 68.648 1.00 42.30 N +ANISOU 5209 N SER B 279 7332 6283 2455 1109 -225 84 N +ATOM 5210 CA SER B 279 34.600 8.561 69.461 1.00 43.21 C +ANISOU 5210 CA SER B 279 7503 6462 2451 1040 -326 12 C +ATOM 5211 C SER B 279 35.927 7.827 69.712 1.00 43.80 C +ANISOU 5211 C SER B 279 7538 6647 2457 1071 -522 77 C +ATOM 5212 O SER B 279 36.961 8.449 69.933 1.00 44.16 O +ANISOU 5212 O SER B 279 7543 6768 2465 1014 -653 32 O +ATOM 5213 CB SER B 279 33.943 8.939 70.787 1.00 44.30 C +ANISOU 5213 CB SER B 279 7839 6571 2422 980 -234 -47 C +ATOM 5214 OG SER B 279 32.716 9.617 70.559 1.00 43.80 O +ANISOU 5214 OG SER B 279 7787 6392 2462 967 -35 -99 O +ATOM 5215 N ALA B 280 35.898 6.499 69.683 1.00 43.94 N +ANISOU 5215 N ALA B 280 7556 6664 2474 1159 -541 189 N +ATOM 5216 CA ALA B 280 37.124 5.727 69.803 1.00 44.71 C +ANISOU 5216 CA ALA B 280 7585 6844 2558 1216 -712 276 C +ATOM 5217 C ALA B 280 37.953 5.827 68.538 1.00 44.56 C +ANISOU 5217 C ALA B 280 7362 6843 2723 1246 -757 268 C +ATOM 5218 O ALA B 280 39.180 5.925 68.608 1.00 45.74 O +ANISOU 5218 O ALA B 280 7412 7079 2888 1247 -906 284 O +ATOM 5219 CB ALA B 280 36.803 4.288 70.083 1.00 45.02 C +ANISOU 5219 CB ALA B 280 7686 6844 2575 1310 -688 403 C +ATOM 5220 N LEU B 281 37.279 5.778 67.384 1.00 43.31 N +ANISOU 5220 N LEU B 281 7141 6610 2702 1263 -628 247 N +ATOM 5221 CA LEU B 281 37.930 5.958 66.090 1.00 42.76 C +ANISOU 5221 CA LEU B 281 6903 6554 2787 1271 -636 227 C +ATOM 5222 C LEU B 281 38.487 7.359 65.923 1.00 43.21 C +ANISOU 5222 C LEU B 281 6894 6655 2866 1181 -682 141 C +ATOM 5223 O LEU B 281 39.504 7.556 65.250 1.00 44.12 O +ANISOU 5223 O LEU B 281 6868 6819 3075 1178 -741 134 O +ATOM 5224 CB LEU B 281 36.945 5.687 64.956 1.00 41.27 C +ANISOU 5224 CB LEU B 281 6694 6290 2697 1277 -495 222 C +ATOM 5225 CG LEU B 281 36.608 4.206 64.752 1.00 41.36 C +ANISOU 5225 CG LEU B 281 6732 6247 2734 1354 -442 292 C +ATOM 5226 CD1 LEU B 281 35.391 3.998 63.870 1.00 40.05 C +ANISOU 5226 CD1 LEU B 281 6577 6013 2625 1325 -313 279 C +ATOM 5227 CD2 LEU B 281 37.785 3.452 64.188 1.00 41.74 C +ANISOU 5227 CD2 LEU B 281 6670 6317 2873 1423 -493 325 C +ATOM 5228 N THR B 282 37.797 8.332 66.507 1.00 43.27 N +ANISOU 5228 N THR B 282 7005 6633 2803 1106 -632 74 N +ATOM 5229 CA THR B 282 38.258 9.709 66.521 1.00 43.78 C +ANISOU 5229 CA THR B 282 7037 6713 2883 1008 -660 -16 C +ATOM 5230 C THR B 282 39.562 9.865 67.301 1.00 45.07 C +ANISOU 5230 C THR B 282 7173 6981 2967 965 -836 -31 C +ATOM 5231 O THR B 282 40.518 10.487 66.816 1.00 44.54 O +ANISOU 5231 O THR B 282 6977 6959 2985 916 -903 -65 O +ATOM 5232 CB THR B 282 37.160 10.599 67.097 1.00 44.32 C +ANISOU 5232 CB THR B 282 7240 6698 2900 948 -539 -88 C +ATOM 5233 OG1 THR B 282 36.082 10.619 66.156 1.00 43.06 O +ANISOU 5233 OG1 THR B 282 7045 6454 2861 982 -401 -58 O +ATOM 5234 CG2 THR B 282 37.664 12.017 67.342 1.00 45.58 C +ANISOU 5234 CG2 THR B 282 7402 6853 3063 836 -561 -196 C +ATOM 5235 N HIS B 283 39.598 9.286 68.499 1.00 46.07 N +ANISOU 5235 N HIS B 283 7416 7154 2932 975 -914 3 N +ATOM 5236 CA HIS B 283 40.847 9.154 69.230 1.00 47.86 C +ANISOU 5236 CA HIS B 283 7599 7504 3079 948 -1117 32 C +ATOM 5237 C HIS B 283 41.954 8.513 68.389 1.00 47.80 C +ANISOU 5237 C HIS B 283 7374 7550 3234 1030 -1206 113 C +ATOM 5238 O HIS B 283 43.072 9.014 68.355 1.00 49.16 O +ANISOU 5238 O HIS B 283 7416 7806 3454 974 -1333 92 O +ATOM 5239 CB HIS B 283 40.623 8.315 70.480 1.00 49.36 C +ANISOU 5239 CB HIS B 283 7945 7734 3074 977 -1185 110 C +ATOM 5240 CG HIS B 283 41.874 8.020 71.242 1.00 51.55 C +ANISOU 5240 CG HIS B 283 8168 8153 3266 961 -1424 181 C +ATOM 5241 ND1 HIS B 283 42.643 6.901 71.009 1.00 51.98 N +ANISOU 5241 ND1 HIS B 283 8083 8252 3416 1086 -1530 330 N +ATOM 5242 CD2 HIS B 283 42.486 8.701 72.238 1.00 53.80 C +ANISOU 5242 CD2 HIS B 283 8511 8545 3383 830 -1581 128 C +ATOM 5243 CE1 HIS B 283 43.677 6.907 71.833 1.00 54.89 C +ANISOU 5243 CE1 HIS B 283 8407 8756 3690 1043 -1758 387 C +ATOM 5244 NE2 HIS B 283 43.598 7.983 72.596 1.00 55.77 N +ANISOU 5244 NE2 HIS B 283 8643 8918 3626 878 -1803 263 N +ATOM 5245 N ASP B 284 41.654 7.403 67.725 1.00 46.81 N +ANISOU 5245 N ASP B 284 7210 7372 3203 1154 -1129 199 N +ATOM 5246 CA ASP B 284 42.667 6.683 66.947 1.00 47.12 C +ANISOU 5246 CA ASP B 284 7056 7440 3406 1243 -1175 270 C +ATOM 5247 C ASP B 284 43.112 7.469 65.693 1.00 46.27 C +ANISOU 5247 C ASP B 284 6796 7326 3456 1195 -1110 195 C +ATOM 5248 O ASP B 284 44.261 7.363 65.247 1.00 46.27 O +ANISOU 5248 O ASP B 284 6615 7382 3582 1218 -1173 219 O +ATOM 5249 CB ASP B 284 42.154 5.291 66.545 1.00 46.91 C +ANISOU 5249 CB ASP B 284 7054 7331 3436 1374 -1076 359 C +ATOM 5250 CG ASP B 284 42.036 4.309 67.721 1.00 48.43 C +ANISOU 5250 CG ASP B 284 7359 7531 3508 1444 -1156 476 C +ATOM 5251 OD1 ASP B 284 42.508 4.581 68.868 1.00 50.67 O +ANISOU 5251 OD1 ASP B 284 7688 7909 3652 1400 -1318 509 O +ATOM 5252 OD2 ASP B 284 41.455 3.227 67.477 1.00 47.93 O +ANISOU 5252 OD2 ASP B 284 7347 7377 3485 1535 -1054 540 O +ATOM 5253 N ALA B 285 42.211 8.266 65.135 1.00 45.02 N +ANISOU 5253 N ALA B 285 6704 7100 3300 1129 -980 116 N +ATOM 5254 CA ALA B 285 42.582 9.186 64.057 1.00 44.61 C +ANISOU 5254 CA ALA B 285 6537 7043 3368 1062 -925 56 C +ATOM 5255 C ALA B 285 43.718 10.135 64.462 1.00 46.04 C +ANISOU 5255 C ALA B 285 6621 7305 3564 964 -1052 6 C +ATOM 5256 O ALA B 285 44.635 10.366 63.684 1.00 45.95 O +ANISOU 5256 O ALA B 285 6444 7328 3684 947 -1057 2 O +ATOM 5257 CB ALA B 285 41.364 9.977 63.610 1.00 43.27 C +ANISOU 5257 CB ALA B 285 6466 6786 3188 1006 -789 5 C +ATOM 5258 N ILE B 286 43.659 10.660 65.684 1.00 47.56 N +ANISOU 5258 N ILE B 286 6922 7529 3618 889 -1148 -36 N +ATOM 5259 CA ILE B 286 44.718 11.541 66.199 1.00 49.22 C +ANISOU 5259 CA ILE B 286 7055 7823 3820 769 -1289 -94 C +ATOM 5260 C ILE B 286 46.030 10.793 66.404 1.00 50.96 C +ANISOU 5260 C ILE B 286 7097 8163 4099 820 -1460 -7 C +ATOM 5261 O ILE B 286 47.081 11.352 66.143 1.00 51.96 O +ANISOU 5261 O ILE B 286 7058 8354 4330 749 -1535 -33 O +ATOM 5262 CB ILE B 286 44.293 12.238 67.519 1.00 50.04 C +ANISOU 5262 CB ILE B 286 7350 7933 3729 655 -1345 -178 C +ATOM 5263 CG1 ILE B 286 43.008 13.044 67.286 1.00 48.87 C +ANISOU 5263 CG1 ILE B 286 7351 7645 3571 617 -1151 -261 C +ATOM 5264 CG2 ILE B 286 45.393 13.145 68.052 1.00 51.64 C +ANISOU 5264 CG2 ILE B 286 7481 8226 3913 502 -1501 -254 C +ATOM 5265 CD1 ILE B 286 43.034 13.927 66.073 1.00 48.01 C +ANISOU 5265 CD1 ILE B 286 7141 7463 3637 578 -1038 -298 C +ATOM 5266 N LEU B 287 45.977 9.545 66.881 1.00 51.87 N +ANISOU 5266 N LEU B 287 7237 8304 4167 945 -1518 105 N +ATOM 5267 CA LEU B 287 47.179 8.679 66.915 1.00 53.42 C +ANISOU 5267 CA LEU B 287 7234 8589 4474 1036 -1656 222 C +ATOM 5268 C LEU B 287 47.807 8.499 65.540 1.00 52.41 C +ANISOU 5268 C LEU B 287 6896 8431 4584 1096 -1545 229 C +ATOM 5269 O LEU B 287 49.029 8.578 65.396 1.00 53.67 O +ANISOU 5269 O LEU B 287 6839 8673 4880 1088 -1641 258 O +ATOM 5270 CB LEU B 287 46.850 7.290 67.450 1.00 54.24 C +ANISOU 5270 CB LEU B 287 7410 8676 4521 1184 -1683 358 C +ATOM 5271 CG LEU B 287 46.506 7.152 68.934 1.00 56.47 C +ANISOU 5271 CG LEU B 287 7876 9017 4562 1147 -1825 401 C +ATOM 5272 CD1 LEU B 287 46.430 5.662 69.293 1.00 57.48 C +ANISOU 5272 CD1 LEU B 287 8026 9123 4691 1313 -1854 573 C +ATOM 5273 CD2 LEU B 287 47.502 7.879 69.854 1.00 58.87 C +ANISOU 5273 CD2 LEU B 287 8117 9475 4773 1013 -2068 387 C +ATOM 5274 N VAL B 288 46.957 8.239 64.541 1.00 50.09 N +ANISOU 5274 N VAL B 288 6670 8027 4335 1147 -1339 204 N +ATOM 5275 CA VAL B 288 47.389 8.033 63.151 1.00 49.28 C +ANISOU 5275 CA VAL B 288 6417 7888 4418 1189 -1197 196 C +ATOM 5276 C VAL B 288 47.984 9.291 62.577 1.00 49.30 C +ANISOU 5276 C VAL B 288 6310 7923 4498 1057 -1182 114 C +ATOM 5277 O VAL B 288 49.053 9.245 61.988 1.00 50.31 O +ANISOU 5277 O VAL B 288 6233 8092 4788 1067 -1174 128 O +ATOM 5278 CB VAL B 288 46.214 7.588 62.265 1.00 47.52 C +ANISOU 5278 CB VAL B 288 6325 7552 4175 1232 -1000 177 C +ATOM 5279 CG1 VAL B 288 46.488 7.831 60.790 1.00 47.33 C +ANISOU 5279 CG1 VAL B 288 6200 7502 4279 1206 -845 133 C +ATOM 5280 CG2 VAL B 288 45.920 6.124 62.519 1.00 47.94 C +ANISOU 5280 CG2 VAL B 288 6428 7557 4227 1376 -980 264 C +ATOM 5281 N ILE B 289 47.286 10.407 62.738 1.00 48.41 N +ANISOU 5281 N ILE B 289 6330 7779 4285 935 -1159 31 N +ATOM 5282 CA ILE B 289 47.825 11.694 62.319 1.00 49.38 C +ANISOU 5282 CA ILE B 289 6367 7914 4477 796 -1148 -43 C +ATOM 5283 C ILE B 289 49.144 12.056 63.017 1.00 52.31 C +ANISOU 5283 C ILE B 289 6572 8400 4901 722 -1333 -48 C +ATOM 5284 O ILE B 289 50.101 12.425 62.360 1.00 53.71 O +ANISOU 5284 O ILE B 289 6561 8612 5233 675 -1314 -57 O +ATOM 5285 CB ILE B 289 46.790 12.820 62.507 1.00 48.30 C +ANISOU 5285 CB ILE B 289 6414 7698 4238 689 -1087 -124 C +ATOM 5286 CG1 ILE B 289 45.716 12.730 61.416 1.00 45.96 C +ANISOU 5286 CG1 ILE B 289 6202 7303 3956 733 -901 -108 C +ATOM 5287 CG2 ILE B 289 47.451 14.186 62.474 1.00 49.66 C +ANISOU 5287 CG2 ILE B 289 6518 7879 4471 529 -1114 -204 C +ATOM 5288 CD1 ILE B 289 44.381 13.332 61.786 1.00 44.62 C +ANISOU 5288 CD1 ILE B 289 6224 7042 3685 699 -839 -143 C +ATOM 5289 N ALA B 290 49.218 11.964 64.334 1.00 54.95 N +ANISOU 5289 N ALA B 290 6972 8801 5102 697 -1513 -38 N +ATOM 5290 CA ALA B 290 50.494 12.241 65.025 1.00 58.37 C +ANISOU 5290 CA ALA B 290 7233 9367 5575 615 -1725 -29 C +ATOM 5291 C ALA B 290 51.626 11.358 64.503 1.00 60.45 C +ANISOU 5291 C ALA B 290 7223 9695 6047 731 -1757 78 C +ATOM 5292 O ALA B 290 52.715 11.869 64.210 1.00 62.45 O +ANISOU 5292 O ALA B 290 7258 10016 6453 652 -1806 63 O +ATOM 5293 CB ALA B 290 50.358 12.081 66.524 1.00 59.61 C +ANISOU 5293 CB ALA B 290 7521 9603 5524 578 -1926 -12 C +ATOM 5294 N GLU B 291 51.365 10.055 64.349 1.00 60.60 N +ANISOU 5294 N GLU B 291 7250 9681 6093 915 -1706 182 N +ATOM 5295 CA GLU B 291 52.406 9.124 63.886 1.00 62.58 C +ANISOU 5295 CA GLU B 291 7244 9965 6565 1049 -1708 289 C +ATOM 5296 C GLU B 291 52.917 9.483 62.475 1.00 61.68 C +ANISOU 5296 C GLU B 291 6969 9810 6654 1028 -1511 233 C +ATOM 5297 O GLU B 291 54.123 9.404 62.203 1.00 62.94 O +ANISOU 5297 O GLU B 291 6860 10034 7019 1042 -1542 274 O +ATOM 5298 CB GLU B 291 51.897 7.671 63.930 1.00 63.37 C +ANISOU 5298 CB GLU B 291 7419 9996 6662 1247 -1649 396 C +ATOM 5299 CG GLU B 291 52.877 6.618 63.398 1.00 65.90 C +ANISOU 5299 CG GLU B 291 7490 10309 7237 1410 -1604 503 C +ATOM 5300 CD GLU B 291 54.133 6.491 64.247 1.00 69.78 C +ANISOU 5300 CD GLU B 291 7739 10939 7836 1428 -1855 621 C +ATOM 5301 OE1 GLU B 291 54.002 6.049 65.420 1.00 71.65 O +ANISOU 5301 OE1 GLU B 291 8051 11232 7938 1465 -2058 726 O +ATOM 5302 OE2 GLU B 291 55.242 6.816 63.731 1.00 71.74 O +ANISOU 5302 OE2 GLU B 291 7714 11241 8301 1402 -1850 619 O +ATOM 5303 N ALA B 292 52.000 9.872 61.594 1.00 59.28 N +ANISOU 5303 N ALA B 292 6826 9405 6293 990 -1309 151 N +ATOM 5304 CA ALA B 292 52.358 10.221 60.226 1.00 59.10 C +ANISOU 5304 CA ALA B 292 6697 9343 6415 956 -1109 105 C +ATOM 5305 C ALA B 292 53.215 11.481 60.180 1.00 60.36 C +ANISOU 5305 C ALA B 292 6711 9565 6656 787 -1165 48 C +ATOM 5306 O ALA B 292 54.175 11.538 59.417 1.00 61.43 O +ANISOU 5306 O ALA B 292 6632 9724 6982 777 -1079 53 O +ATOM 5307 CB ALA B 292 51.110 10.391 59.354 1.00 56.56 C +ANISOU 5307 CB ALA B 292 6592 8913 5983 939 -916 51 C +ATOM 5308 N PHE B 293 52.870 12.493 60.970 1.00 60.66 N +ANISOU 5308 N PHE B 293 6868 9619 6560 646 -1287 -14 N +ATOM 5309 CA PHE B 293 53.642 13.736 60.943 1.00 62.40 C +ANISOU 5309 CA PHE B 293 6968 9881 6860 464 -1332 -82 C +ATOM 5310 C PHE B 293 54.968 13.615 61.656 1.00 65.57 C +ANISOU 5310 C PHE B 293 7113 10419 7379 434 -1541 -39 C +ATOM 5311 O PHE B 293 55.922 14.271 61.250 1.00 66.82 O +ANISOU 5311 O PHE B 293 7070 10618 7699 325 -1530 -67 O +ATOM 5312 CB PHE B 293 52.834 14.939 61.432 1.00 61.97 C +ANISOU 5312 CB PHE B 293 7132 9767 6647 310 -1352 -182 C +ATOM 5313 CG PHE B 293 51.888 15.448 60.393 1.00 60.55 C +ANISOU 5313 CG PHE B 293 7102 9458 6446 296 -1130 -213 C +ATOM 5314 CD1 PHE B 293 52.343 16.263 59.346 1.00 61.07 C +ANISOU 5314 CD1 PHE B 293 7073 9487 6643 198 -992 -236 C +ATOM 5315 CD2 PHE B 293 50.565 15.064 60.408 1.00 58.49 C +ANISOU 5315 CD2 PHE B 293 7063 9116 6042 382 -1058 -200 C +ATOM 5316 CE1 PHE B 293 51.480 16.694 58.357 1.00 59.32 C +ANISOU 5316 CE1 PHE B 293 6985 9157 6393 188 -805 -234 C +ATOM 5317 CE2 PHE B 293 49.696 15.501 59.428 1.00 57.10 C +ANISOU 5317 CE2 PHE B 293 7003 8836 5854 371 -878 -205 C +ATOM 5318 CZ PHE B 293 50.153 16.306 58.395 1.00 57.66 C +ANISOU 5318 CZ PHE B 293 6987 8879 6042 276 -758 -214 C +ATOM 5319 N ARG B 294 55.049 12.762 62.682 1.00 67.46 N +ANISOU 5319 N ARG B 294 7348 10734 7548 529 -1732 41 N +ATOM 5320 CA ARG B 294 56.338 12.454 63.288 1.00 71.45 C +ANISOU 5320 CA ARG B 294 7574 11382 8189 531 -1947 125 C +ATOM 5321 C ARG B 294 57.235 11.766 62.284 1.00 72.57 C +ANISOU 5321 C ARG B 294 7435 11521 8615 659 -1809 200 C +ATOM 5322 O ARG B 294 58.423 12.063 62.210 1.00 74.56 O +ANISOU 5322 O ARG B 294 7400 11863 9066 595 -1880 221 O +ATOM 5323 CB ARG B 294 56.188 11.553 64.508 1.00 73.57 C +ANISOU 5323 CB ARG B 294 7904 11725 8322 631 -2170 233 C +ATOM 5324 CG ARG B 294 55.709 12.255 65.770 1.00 75.07 C +ANISOU 5324 CG ARG B 294 8309 11973 8240 471 -2368 165 C +ATOM 5325 CD ARG B 294 56.074 11.443 67.012 1.00 78.27 C +ANISOU 5325 CD ARG B 294 8677 12512 8550 533 -2650 304 C +ATOM 5326 NE ARG B 294 55.376 10.163 66.990 1.00 78.09 N +ANISOU 5326 NE ARG B 294 8768 12412 8490 756 -2567 419 N +ATOM 5327 CZ ARG B 294 54.192 9.910 67.554 1.00 77.75 C +ANISOU 5327 CZ ARG B 294 9032 12308 8202 783 -2538 405 C +ATOM 5328 NH1 ARG B 294 53.536 10.835 68.266 1.00 77.85 N +ANISOU 5328 NH1 ARG B 294 9283 12326 7970 608 -2585 279 N +ATOM 5329 NH2 ARG B 294 53.662 8.697 67.406 1.00 77.29 N +ANISOU 5329 NH2 ARG B 294 9041 12169 8156 985 -2445 514 N +ATOM 5330 N TYR B 295 56.655 10.844 61.516 1.00 71.98 N +ANISOU 5330 N TYR B 295 7444 11339 8563 829 -1600 232 N +ATOM 5331 CA TYR B 295 57.357 10.154 60.429 1.00 72.97 C +ANISOU 5331 CA TYR B 295 7354 11427 8943 952 -1399 275 C +ATOM 5332 C TYR B 295 57.949 11.143 59.428 1.00 74.15 C +ANISOU 5332 C TYR B 295 7372 11573 9229 807 -1239 190 C +ATOM 5333 O TYR B 295 59.127 11.048 59.118 1.00 75.94 O +ANISOU 5333 O TYR B 295 7295 11855 9703 819 -1219 230 O +ATOM 5334 CB TYR B 295 56.404 9.166 59.736 1.00 70.79 C +ANISOU 5334 CB TYR B 295 7270 11019 8608 1108 -1180 280 C +ATOM 5335 CG TYR B 295 56.915 8.546 58.461 1.00 71.27 C +ANISOU 5335 CG TYR B 295 7185 11012 8882 1205 -910 279 C +ATOM 5336 CD1 TYR B 295 57.636 7.361 58.487 1.00 73.16 C +ANISOU 5336 CD1 TYR B 295 7223 11238 9333 1391 -885 380 C +ATOM 5337 CD2 TYR B 295 56.663 9.137 57.228 1.00 69.89 C +ANISOU 5337 CD2 TYR B 295 7083 10777 8693 1109 -668 180 C +ATOM 5338 CE1 TYR B 295 58.097 6.778 57.319 1.00 73.98 C +ANISOU 5338 CE1 TYR B 295 7208 11263 9635 1477 -603 359 C +ATOM 5339 CE2 TYR B 295 57.122 8.573 56.048 1.00 70.73 C +ANISOU 5339 CE2 TYR B 295 7084 10825 8964 1178 -401 164 C +ATOM 5340 CZ TYR B 295 57.842 7.398 56.088 1.00 72.96 C +ANISOU 5340 CZ TYR B 295 7172 11087 9461 1360 -356 240 C +ATOM 5341 OH TYR B 295 58.287 6.867 54.888 1.00 73.45 O +ANISOU 5341 OH TYR B 295 7145 11076 9686 1419 -53 201 O +ATOM 5342 N LEU B 296 57.146 12.099 58.954 1.00 74.25 N +ANISOU 5342 N LEU B 296 7601 11517 9091 673 -1127 87 N +ATOM 5343 CA LEU B 296 57.607 13.078 57.950 1.00 76.48 C +ANISOU 5343 CA LEU B 296 7795 11779 9483 528 -958 19 C +ATOM 5344 C LEU B 296 58.741 13.961 58.455 1.00 80.64 C +ANISOU 5344 C LEU B 296 8082 12410 10147 367 -1118 4 C +ATOM 5345 O LEU B 296 59.642 14.304 57.696 1.00 81.35 O +ANISOU 5345 O LEU B 296 7954 12515 10440 305 -991 -4 O +ATOM 5346 CB LEU B 296 56.459 13.969 57.464 1.00 74.04 C +ANISOU 5346 CB LEU B 296 7775 11372 8986 419 -838 -59 C +ATOM 5347 CG LEU B 296 55.347 13.265 56.680 1.00 72.14 C +ANISOU 5347 CG LEU B 296 7753 11032 8622 535 -651 -51 C +ATOM 5348 CD1 LEU B 296 54.126 14.167 56.569 1.00 70.01 C +ANISOU 5348 CD1 LEU B 296 7755 10683 8160 436 -617 -100 C +ATOM 5349 CD2 LEU B 296 55.808 12.810 55.295 1.00 72.86 C +ANISOU 5349 CD2 LEU B 296 7741 11095 8847 580 -390 -45 C +ATOM 5350 N ARG B 297 58.688 14.345 59.724 1.00 84.04 N +ANISOU 5350 N ARG B 297 8559 12912 10459 284 -1388 -6 N +ATOM 5351 CA ARG B 297 59.772 15.117 60.306 1.00 89.61 C +ANISOU 5351 CA ARG B 297 9035 13732 11281 112 -1576 -25 C +ATOM 5352 C ARG B 297 61.049 14.283 60.283 1.00 94.57 C +ANISOU 5352 C ARG B 297 9287 14466 12180 222 -1639 88 C +ATOM 5353 O ARG B 297 62.119 14.774 59.932 1.00 96.85 O +ANISOU 5353 O ARG B 297 9297 14810 12691 119 -1619 82 O +ATOM 5354 CB ARG B 297 59.433 15.550 61.734 1.00 90.74 C +ANISOU 5354 CB ARG B 297 9326 13941 11207 0 -1863 -63 C +ATOM 5355 CG ARG B 297 60.562 16.287 62.445 1.00 94.19 C +ANISOU 5355 CG ARG B 297 9532 14516 11740 -199 -2098 -89 C +ATOM 5356 CD ARG B 297 60.167 16.702 63.851 1.00 95.70 C +ANISOU 5356 CD ARG B 297 9914 14773 11673 -331 -2368 -146 C +ATOM 5357 NE ARG B 297 61.246 17.398 64.548 1.00 99.06 N +ANISOU 5357 NE ARG B 297 10125 15342 12168 -550 -2613 -180 N +ATOM 5358 CZ ARG B 297 62.256 16.808 65.191 1.00102.41 C +ANISOU 5358 CZ ARG B 297 10265 15946 12697 -526 -2875 -61 C +ATOM 5359 NH1 ARG B 297 62.367 15.482 65.245 1.00102.74 N +ANISOU 5359 NH1 ARG B 297 10196 16034 12806 -274 -2918 109 N +ATOM 5360 NH2 ARG B 297 63.179 17.553 65.789 1.00105.39 N +ANISOU 5360 NH2 ARG B 297 10458 16458 13127 -760 -3103 -106 N +ATOM 5361 N ARG B 298 60.923 13.010 60.629 1.00 97.64 N +ANISOU 5361 N ARG B 298 9660 14868 12570 438 -1697 200 N +ATOM 5362 CA ARG B 298 62.064 12.099 60.599 1.00101.78 C +ANISOU 5362 CA ARG B 298 9825 15466 13378 584 -1737 332 C +ATOM 5363 C ARG B 298 62.646 11.857 59.191 1.00102.89 C +ANISOU 5363 C ARG B 298 9775 15533 13785 654 -1406 323 C +ATOM 5364 O ARG B 298 63.857 11.679 59.057 1.00106.74 O +ANISOU 5364 O ARG B 298 9896 16092 14567 678 -1417 391 O +ATOM 5365 CB ARG B 298 61.706 10.776 61.282 1.00102.86 C +ANISOU 5365 CB ARG B 298 10020 15603 13457 810 -1854 463 C +ATOM 5366 CG ARG B 298 61.953 10.791 62.784 1.00105.45 C +ANISOU 5366 CG ARG B 298 10312 16083 13670 757 -2247 548 C +ATOM 5367 CD ARG B 298 61.924 9.405 63.400 1.00107.55 C +ANISOU 5367 CD ARG B 298 10544 16360 13958 995 -2365 728 C +ATOM 5368 NE ARG B 298 60.609 9.108 63.947 1.00106.72 N +ANISOU 5368 NE ARG B 298 10826 16188 13533 1034 -2389 708 N +ATOM 5369 CZ ARG B 298 59.666 8.386 63.345 1.00106.48 C +ANISOU 5369 CZ ARG B 298 11012 16001 13442 1183 -2149 692 C +ATOM 5370 NH1 ARG B 298 59.868 7.836 62.150 1.00106.89 N +ANISOU 5370 NH1 ARG B 298 10958 15942 13713 1311 -1858 685 N +ATOM 5371 NH2 ARG B 298 58.496 8.197 63.952 1.00105.81 N +ANISOU 5371 NH2 ARG B 298 11259 15872 13071 1194 -2194 677 N +ATOM 5372 N GLN B 299 61.802 11.859 58.161 1.00101.52 N +ANISOU 5372 N GLN B 299 9842 15224 13508 676 -1116 243 N +ATOM 5373 CA GLN B 299 62.262 11.739 56.775 1.00102.95 C +ANISOU 5373 CA GLN B 299 9899 15334 13881 705 -780 213 C +ATOM 5374 C GLN B 299 62.803 13.064 56.203 1.00104.95 C +ANISOU 5374 C GLN B 299 10056 15609 14209 473 -691 132 C +ATOM 5375 O GLN B 299 63.394 13.070 55.131 1.00105.80 O +ANISOU 5375 O GLN B 299 10018 15683 14498 468 -425 115 O +ATOM 5376 CB GLN B 299 61.133 11.222 55.865 1.00100.50 C +ANISOU 5376 CB GLN B 299 9899 14885 13400 794 -517 162 C +ATOM 5377 CG GLN B 299 60.527 9.877 56.248 1.00 99.63 C +ANISOU 5377 CG GLN B 299 9908 14722 13226 1014 -545 228 C +ATOM 5378 CD GLN B 299 61.506 8.740 56.101 1.00102.39 C +ANISOU 5378 CD GLN B 299 9962 15065 13876 1207 -465 320 C +ATOM 5379 OE1 GLN B 299 61.883 8.360 54.991 1.00103.67 O +ANISOU 5379 OE1 GLN B 299 10040 15155 14195 1260 -161 285 O +ATOM 5380 NE2 GLN B 299 61.936 8.193 57.229 1.00104.29 N +ANISOU 5380 NE2 GLN B 299 10044 15378 14202 1313 -730 446 N +ATOM 5381 N ARG B 300 62.595 14.169 56.923 1.00107.00 N +ANISOU 5381 N ARG B 300 10410 15914 14330 279 -895 78 N +ATOM 5382 CA ARG B 300 63.073 15.513 56.549 1.00109.55 C +ANISOU 5382 CA ARG B 300 10660 16243 14719 38 -841 2 C +ATOM 5383 C ARG B 300 62.391 16.021 55.288 1.00109.05 C +ANISOU 5383 C ARG B 300 10822 16051 14558 -18 -530 -61 C +ATOM 5384 O ARG B 300 63.026 16.615 54.418 1.00109.73 O +ANISOU 5384 O ARG B 300 10776 16121 14793 -131 -336 -84 O +ATOM 5385 CB ARG B 300 64.603 15.574 56.440 1.00113.43 C +ANISOU 5385 CB ARG B 300 10713 16835 15550 -9 -851 46 C +ATOM 5386 CG ARG B 300 65.292 14.989 57.663 1.00116.52 C +ANISOU 5386 CG ARG B 300 10857 17369 16046 59 -1183 143 C +ATOM 5387 CD ARG B 300 66.813 15.051 57.624 1.00120.85 C +ANISOU 5387 CD ARG B 300 10932 18030 16955 11 -1225 204 C +ATOM 5388 NE ARG B 300 67.347 16.335 57.166 1.00122.72 N +ANISOU 5388 NE ARG B 300 11071 18269 17286 -248 -1137 114 N +ATOM 5389 CZ ARG B 300 67.168 17.507 57.775 1.00123.13 C +ANISOU 5389 CZ ARG B 300 11245 18346 17193 -495 -1317 23 C +ATOM 5390 NH1 ARG B 300 66.443 17.603 58.885 1.00122.61 N +ANISOU 5390 NH1 ARG B 300 11415 18311 16858 -526 -1591 -1 N +ATOM 5391 NH2 ARG B 300 67.710 18.605 57.258 1.00124.45 N +ANISOU 5391 NH2 ARG B 300 11308 18493 17484 -721 -1200 -49 N +ATOM 5392 N VAL B 301 61.084 15.792 55.225 1.00109.40 N +ANISOU 5392 N VAL B 301 11207 16011 14349 52 -494 -79 N +ATOM 5393 CA VAL B 301 60.271 16.223 54.111 1.00109.35 C +ANISOU 5393 CA VAL B 301 11441 15893 14211 5 -245 -116 C +ATOM 5394 C VAL B 301 59.789 17.647 54.337 1.00111.49 C +ANISOU 5394 C VAL B 301 11880 16114 14364 -198 -307 -174 C +ATOM 5395 O VAL B 301 59.410 18.016 55.448 1.00109.59 O +ANISOU 5395 O VAL B 301 11735 15888 14015 -246 -535 -204 O +ATOM 5396 CB VAL B 301 59.049 15.307 53.920 1.00106.72 C +ANISOU 5396 CB VAL B 301 11380 15494 13674 169 -185 -101 C +ATOM 5397 CG1 VAL B 301 58.164 15.825 52.786 1.00105.48 C +ANISOU 5397 CG1 VAL B 301 11471 15241 13364 100 34 -124 C +ATOM 5398 CG2 VAL B 301 59.494 13.879 53.642 1.00106.89 C +ANISOU 5398 CG2 VAL B 301 11258 15531 13822 370 -89 -54 C +ATOM 5399 N ASP B 302 59.810 18.431 53.262 1.00116.62 N +ANISOU 5399 N ASP B 302 12573 16697 15039 -317 -86 -186 N +ATOM 5400 CA ASP B 302 59.318 19.808 53.253 1.00120.09 C +ANISOU 5400 CA ASP B 302 13182 17050 15394 -501 -86 -225 C +ATOM 5401 C ASP B 302 57.784 19.809 53.260 1.00118.46 C +ANISOU 5401 C ASP B 302 13319 16751 14938 -435 -86 -217 C +ATOM 5402 O ASP B 302 57.153 19.060 52.513 1.00116.76 O +ANISOU 5402 O ASP B 302 13225 16514 14623 -312 48 -176 O +ATOM 5403 CB ASP B 302 59.838 20.526 51.996 1.00123.98 C +ANISOU 5403 CB ASP B 302 13610 17498 15999 -632 170 -208 C +ATOM 5404 CG ASP B 302 59.777 22.057 52.095 1.00126.92 C +ANISOU 5404 CG ASP B 302 14058 17782 16383 -852 160 -241 C +ATOM 5405 OD1 ASP B 302 58.879 22.606 52.782 1.00126.68 O +ANISOU 5405 OD1 ASP B 302 14242 17678 16213 -882 33 -273 O +ATOM 5406 OD2 ASP B 302 60.628 22.708 51.450 1.00129.39 O +ANISOU 5406 OD2 ASP B 302 14218 18085 16858 -994 304 -234 O +ATOM 5407 N VAL B 303 57.203 20.645 54.120 1.00119.56 N +ANISOU 5407 N VAL B 303 13607 16835 14985 -524 -232 -264 N +ATOM 5408 CA VAL B 303 55.756 20.859 54.190 1.00116.98 C +ANISOU 5408 CA VAL B 303 13583 16405 14459 -481 -225 -257 C +ATOM 5409 C VAL B 303 55.477 22.340 54.516 1.00116.41 C +ANISOU 5409 C VAL B 303 13623 16218 14390 -660 -242 -307 C +ATOM 5410 O VAL B 303 56.241 22.977 55.252 1.00118.52 O +ANISOU 5410 O VAL B 303 13773 16506 14751 -800 -357 -381 O +ATOM 5411 CB VAL B 303 55.100 19.933 55.248 1.00116.41 C +ANISOU 5411 CB VAL B 303 13607 16375 14248 -334 -403 -270 C +ATOM 5412 CG1 VAL B 303 55.227 18.472 54.837 1.00115.22 C +ANISOU 5412 CG1 VAL B 303 13381 16296 14101 -150 -354 -214 C +ATOM 5413 CG2 VAL B 303 55.705 20.147 56.635 1.00117.98 C +ANISOU 5413 CG2 VAL B 303 13708 16645 14473 -407 -643 -337 C +ATOM 5414 N SER B 304 54.401 22.898 53.961 1.00112.96 N +ANISOU 5414 N SER B 304 13405 15654 13861 -661 -127 -263 N +ATOM 5415 CA SER B 304 54.028 24.299 54.229 1.00111.87 C +ANISOU 5415 CA SER B 304 13390 15369 13746 -809 -112 -300 C +ATOM 5416 C SER B 304 52.529 24.576 54.022 1.00108.72 C +ANISOU 5416 C SER B 304 13248 14839 13221 -735 -50 -242 C +ATOM 5417 O SER B 304 52.007 24.552 52.905 1.00105.04 O +ANISOU 5417 O SER B 304 12853 14335 12720 -692 90 -130 O +ATOM 5418 CB SER B 304 54.872 25.253 53.371 1.00111.93 C +ANISOU 5418 CB SER B 304 13285 15326 13916 -977 34 -274 C +ATOM 5419 OG SER B 304 56.236 25.183 53.740 1.00112.22 O +ANISOU 5419 OG SER B 304 13067 15470 14098 -1071 -39 -340 O +ATOM 5420 N GLY B 310 46.449 28.439 49.547 1.00 80.35 N +ANISOU 5420 N GLY B 310 10493 10476 9557 -633 538 608 N +ATOM 5421 CA GLY B 310 45.887 29.655 48.995 1.00 82.70 C +ANISOU 5421 CA GLY B 310 10869 10587 9965 -673 630 774 C +ATOM 5422 C GLY B 310 44.372 29.620 48.827 1.00 84.19 C +ANISOU 5422 C GLY B 310 11158 10713 10114 -538 600 925 C +ATOM 5423 O GLY B 310 43.649 30.208 49.629 1.00 84.87 O +ANISOU 5423 O GLY B 310 11302 10632 10311 -488 601 898 O +ATOM 5424 N ASP B 311 43.886 28.916 47.798 1.00 86.27 N +ANISOU 5424 N ASP B 311 11440 11113 10224 -486 576 1079 N +ATOM 5425 CA ASP B 311 42.521 29.136 47.259 1.00 87.09 C +ANISOU 5425 CA ASP B 311 11618 11158 10314 -399 554 1297 C +ATOM 5426 C ASP B 311 41.940 27.956 46.433 1.00 84.82 C +ANISOU 5426 C ASP B 311 11348 11076 9803 -341 476 1392 C +ATOM 5427 O ASP B 311 42.641 27.390 45.610 1.00 84.07 O +ANISOU 5427 O ASP B 311 11238 11134 9569 -412 503 1394 O +ATOM 5428 CB ASP B 311 42.559 30.402 46.373 1.00 90.29 C +ANISOU 5428 CB ASP B 311 12052 11418 10836 -482 653 1512 C +ATOM 5429 CG ASP B 311 41.172 30.950 46.047 1.00 91.95 C +ANISOU 5429 CG ASP B 311 12314 11506 11115 -387 629 1752 C +ATOM 5430 OD1 ASP B 311 40.200 30.555 46.722 1.00 92.34 O +ANISOU 5430 OD1 ASP B 311 12369 11539 11176 -260 558 1717 O +ATOM 5431 OD2 ASP B 311 41.053 31.794 45.129 1.00 93.24 O +ANISOU 5431 OD2 ASP B 311 12505 11585 11336 -436 684 1986 O +ATOM 5432 N CYS B 312 40.653 27.641 46.629 1.00 81.84 N +ANISOU 5432 N CYS B 312 11002 10689 9402 -224 395 1469 N +ATOM 5433 CA CYS B 312 39.930 26.554 45.928 1.00 79.77 C +ANISOU 5433 CA CYS B 312 10763 10606 8939 -180 307 1554 C +ATOM 5434 C CYS B 312 39.732 26.658 44.404 1.00 81.35 C +ANISOU 5434 C CYS B 312 11004 10902 9004 -258 305 1790 C +ATOM 5435 O CYS B 312 39.979 25.693 43.699 1.00 79.46 O +ANISOU 5435 O CYS B 312 10788 10848 8555 -305 288 1766 O +ATOM 5436 CB CYS B 312 38.556 26.384 46.578 1.00 78.23 C +ANISOU 5436 CB CYS B 312 10573 10350 8797 -48 228 1592 C +ATOM 5437 SG CYS B 312 38.659 25.366 48.054 1.00 76.08 S +ANISOU 5437 SG CYS B 312 10287 10115 8504 37 190 1309 S +ATOM 5438 N LEU B 313 39.235 27.786 43.915 1.00 85.89 N +ANISOU 5438 N LEU B 313 11597 11347 9690 -271 322 2021 N +ATOM 5439 CA LEU B 313 39.373 28.118 42.502 1.00 92.15 C +ANISOU 5439 CA LEU B 313 12438 12215 10360 -380 341 2247 C +ATOM 5440 C LEU B 313 40.814 27.916 42.014 1.00 94.58 C +ANISOU 5440 C LEU B 313 12753 12616 10566 -515 457 2129 C +ATOM 5441 O LEU B 313 41.751 28.586 42.464 1.00 92.51 O +ANISOU 5441 O LEU B 313 12452 12237 10460 -564 562 2029 O +ATOM 5442 CB LEU B 313 38.954 29.573 42.242 1.00 97.64 C +ANISOU 5442 CB LEU B 313 13139 12703 11254 -378 377 2497 C +ATOM 5443 CG LEU B 313 39.283 30.234 40.868 1.00101.41 C +ANISOU 5443 CG LEU B 313 13677 13209 11645 -507 425 2755 C +ATOM 5444 CD1 LEU B 313 38.576 29.536 39.706 1.00102.29 C +ANISOU 5444 CD1 LEU B 313 13844 13540 11480 -544 301 2948 C +ATOM 5445 CD2 LEU B 313 38.971 31.735 40.855 1.00102.73 C +ANISOU 5445 CD2 LEU B 313 13842 13118 12074 -487 482 2979 C +ATOM 5446 N ALA B 314 40.965 26.986 41.078 1.00 98.33 N +ANISOU 5446 N ALA B 314 13275 13300 10784 -582 446 2139 N +ATOM 5447 CA ALA B 314 42.259 26.639 40.510 1.00 99.36 C +ANISOU 5447 CA ALA B 314 13410 13537 10805 -703 577 2029 C +ATOM 5448 C ALA B 314 42.569 27.519 39.293 1.00102.16 C +ANISOU 5448 C ALA B 314 13832 13884 11098 -842 667 2258 C +ATOM 5449 O ALA B 314 42.399 27.091 38.141 1.00103.60 O +ANISOU 5449 O ALA B 314 14108 14226 11030 -930 665 2376 O +ATOM 5450 CB ALA B 314 42.264 25.162 40.122 1.00 99.13 C +ANISOU 5450 CB ALA B 314 13415 13716 10531 -709 554 1904 C +ATOM 5451 N ASN B 315 43.016 28.752 39.540 1.00103.22 N +ANISOU 5451 N ASN B 315 13934 13832 11453 -876 751 2321 N +ATOM 5452 CA ASN B 315 43.490 29.650 38.468 1.00104.54 C +ANISOU 5452 CA ASN B 315 14160 13968 11590 -1018 866 2530 C +ATOM 5453 C ASN B 315 44.838 29.152 37.906 1.00103.65 C +ANISOU 5453 C ASN B 315 14038 13987 11354 -1152 1032 2386 C +ATOM 5454 O ASN B 315 45.005 29.030 36.700 1.00104.10 O +ANISOU 5454 O ASN B 315 14190 14169 11191 -1270 1101 2518 O +ATOM 5455 CB ASN B 315 43.599 31.099 38.978 1.00104.91 C +ANISOU 5455 CB ASN B 315 14173 13748 11939 -1016 925 2619 C +ATOM 5456 N PRO B 316 45.803 28.870 38.794 1.00101.84 N +ANISOU 5456 N PRO B 316 13690 13733 11271 -1136 1098 2120 N +ATOM 5457 CA PRO B 316 47.004 28.110 38.484 1.00 99.49 C +ANISOU 5457 CA PRO B 316 13338 13572 10889 -1216 1238 1940 C +ATOM 5458 C PRO B 316 46.762 26.600 38.642 1.00 95.12 C +ANISOU 5458 C PRO B 316 12786 13189 10168 -1129 1169 1771 C +ATOM 5459 O PRO B 316 47.069 25.847 37.720 1.00 96.21 O +ANISOU 5459 O PRO B 316 12982 13480 10090 -1201 1262 1752 O +ATOM 5460 CB PRO B 316 48.023 28.634 39.505 1.00100.31 C +ANISOU 5460 CB PRO B 316 13289 13548 11274 -1227 1299 1764 C +ATOM 5461 N ALA B 317 46.239 26.174 39.807 1.00 88.47 N +ANISOU 5461 N ALA B 317 11885 12305 9422 -983 1026 1643 N +ATOM 5462 CA ALA B 317 45.897 24.757 40.131 1.00 82.30 C +ANISOU 5462 CA ALA B 317 11103 11651 8514 -883 948 1488 C +ATOM 5463 C ALA B 317 46.962 23.950 40.917 1.00 77.03 C +ANISOU 5463 C ALA B 317 10299 11022 7947 -836 1000 1229 C +ATOM 5464 O ALA B 317 48.117 24.377 41.074 1.00 77.67 O +ANISOU 5464 O ALA B 317 10269 11066 8175 -901 1110 1155 O +ATOM 5465 CB ALA B 317 45.434 23.980 38.888 1.00 83.42 C +ANISOU 5465 CB ALA B 317 11379 11958 8357 -946 966 1571 C +ATOM 5466 N VAL B 318 46.537 22.785 41.411 1.00 70.14 N +ANISOU 5466 N VAL B 318 9426 10219 7003 -724 912 1107 N +ATOM 5467 CA VAL B 318 47.346 21.954 42.308 1.00 66.04 C +ANISOU 5467 CA VAL B 318 8776 9725 6589 -645 918 891 C +ATOM 5468 C VAL B 318 48.311 21.047 41.532 1.00 63.99 C +ANISOU 5468 C VAL B 318 8482 9583 6248 -693 1089 795 C +ATOM 5469 O VAL B 318 47.875 20.235 40.711 1.00 63.84 O +ANISOU 5469 O VAL B 318 8577 9658 6022 -709 1131 806 O +ATOM 5470 CB VAL B 318 46.435 21.110 43.226 1.00 64.39 C +ANISOU 5470 CB VAL B 318 8590 9521 6353 -499 759 818 C +ATOM 5471 CG1 VAL B 318 47.221 20.097 44.046 1.00 63.73 C +ANISOU 5471 CG1 VAL B 318 8387 9478 6348 -411 760 625 C +ATOM 5472 CG2 VAL B 318 45.663 22.036 44.158 1.00 64.33 C +ANISOU 5472 CG2 VAL B 318 8591 9380 6469 -447 629 877 C +ATOM 5473 N PRO B 319 49.630 21.191 41.780 1.00 61.83 N +ANISOU 5473 N PRO B 319 8047 9300 6144 -725 1197 696 N +ATOM 5474 CA PRO B 319 50.599 20.348 41.069 1.00 61.63 C +ANISOU 5474 CA PRO B 319 7964 9368 6082 -759 1390 601 C +ATOM 5475 C PRO B 319 50.547 18.881 41.524 1.00 59.09 C +ANISOU 5475 C PRO B 319 7613 9101 5737 -621 1360 455 C +ATOM 5476 O PRO B 319 50.142 18.604 42.637 1.00 56.88 O +ANISOU 5476 O PRO B 319 7294 8786 5531 -502 1189 406 O +ATOM 5477 CB PRO B 319 51.948 21.014 41.388 1.00 63.20 C +ANISOU 5477 CB PRO B 319 7961 9528 6521 -820 1483 551 C +ATOM 5478 CG PRO B 319 51.728 21.749 42.671 1.00 62.47 C +ANISOU 5478 CG PRO B 319 7801 9338 6594 -773 1290 544 C +ATOM 5479 CD PRO B 319 50.290 22.170 42.672 1.00 61.56 C +ANISOU 5479 CD PRO B 319 7872 9168 6348 -747 1156 668 C +ATOM 5480 N TRP B 320 50.951 17.954 40.657 1.00 58.93 N +ANISOU 5480 N TRP B 320 7623 9156 5611 -644 1542 386 N +ATOM 5481 CA TRP B 320 50.891 16.490 40.938 1.00 57.16 C +ANISOU 5481 CA TRP B 320 7391 8962 5364 -519 1550 251 C +ATOM 5482 C TRP B 320 51.525 16.035 42.277 1.00 56.74 C +ANISOU 5482 C TRP B 320 7130 8872 5556 -369 1454 148 C +ATOM 5483 O TRP B 320 51.054 15.091 42.883 1.00 55.86 O +ANISOU 5483 O TRP B 320 7040 8755 5429 -244 1359 88 O +ATOM 5484 CB TRP B 320 51.534 15.686 39.776 1.00 57.81 C +ANISOU 5484 CB TRP B 320 7511 9105 5349 -583 1825 169 C +ATOM 5485 CG TRP B 320 53.036 15.837 39.728 1.00 58.75 C +ANISOU 5485 CG TRP B 320 7413 9218 5691 -601 2016 105 C +ATOM 5486 CD1 TRP B 320 53.743 16.908 39.257 1.00 59.82 C +ANISOU 5486 CD1 TRP B 320 7482 9351 5892 -733 2128 175 C +ATOM 5487 CD2 TRP B 320 54.011 14.919 40.240 1.00 58.87 C +ANISOU 5487 CD2 TRP B 320 7224 9220 5923 -477 2104 -26 C +ATOM 5488 NE1 TRP B 320 55.090 16.704 39.421 1.00 60.73 N +ANISOU 5488 NE1 TRP B 320 7359 9463 6250 -709 2286 85 N +ATOM 5489 CE2 TRP B 320 55.283 15.496 40.027 1.00 60.35 C +ANISOU 5489 CE2 TRP B 320 7213 9410 6305 -546 2267 -32 C +ATOM 5490 CE3 TRP B 320 53.930 13.674 40.874 1.00 57.96 C +ANISOU 5490 CE3 TRP B 320 7064 9085 5873 -312 2059 -126 C +ATOM 5491 CZ2 TRP B 320 56.459 14.870 40.412 1.00 61.74 C +ANISOU 5491 CZ2 TRP B 320 7133 9579 6747 -450 2378 -128 C +ATOM 5492 CZ3 TRP B 320 55.107 13.049 41.254 1.00 59.16 C +ANISOU 5492 CZ3 TRP B 320 6973 9219 6284 -209 2171 -214 C +ATOM 5493 CH2 TRP B 320 56.354 13.649 41.022 1.00 61.12 C +ANISOU 5493 CH2 TRP B 320 7010 9480 6732 -276 2324 -212 C +ATOM 5494 N SER B 321 52.584 16.722 42.715 1.00 57.91 N +ANISOU 5494 N SER B 321 7081 9000 5921 -394 1472 138 N +ATOM 5495 CA SER B 321 53.428 16.294 43.828 1.00 58.38 C +ANISOU 5495 CA SER B 321 6913 9052 6213 -280 1397 51 C +ATOM 5496 C SER B 321 53.001 16.794 45.236 1.00 57.05 C +ANISOU 5496 C SER B 321 6713 8842 6122 -221 1127 65 C +ATOM 5497 O SER B 321 53.629 16.442 46.226 1.00 56.54 O +ANISOU 5497 O SER B 321 6476 8786 6219 -135 1029 7 O +ATOM 5498 CB SER B 321 54.869 16.758 43.563 1.00 60.36 C +ANISOU 5498 CB SER B 321 6943 9320 6672 -359 1554 29 C +ATOM 5499 OG SER B 321 54.939 18.180 43.546 1.00 60.82 O +ANISOU 5499 OG SER B 321 7000 9343 6767 -498 1517 108 O +ATOM 5500 N GLN B 322 51.941 17.594 45.305 1.00 56.43 N +ANISOU 5500 N GLN B 322 6798 8718 5925 -268 1017 146 N +ATOM 5501 CA GLN B 322 51.520 18.243 46.534 1.00 56.12 C +ANISOU 5501 CA GLN B 322 6753 8621 5949 -240 808 152 C +ATOM 5502 C GLN B 322 50.659 17.287 47.359 1.00 54.59 C +ANISOU 5502 C GLN B 322 6635 8428 5676 -93 663 116 C +ATOM 5503 O GLN B 322 49.780 16.635 46.807 1.00 54.72 O +ANISOU 5503 O GLN B 322 6799 8458 5534 -57 692 141 O +ATOM 5504 CB GLN B 322 50.725 19.502 46.197 1.00 56.28 C +ANISOU 5504 CB GLN B 322 6913 8567 5903 -342 788 262 C +ATOM 5505 CG GLN B 322 50.274 20.292 47.429 1.00 56.14 C +ANISOU 5505 CG GLN B 322 6907 8463 5960 -327 612 253 C +ATOM 5506 CD GLN B 322 49.551 21.580 47.065 1.00 56.55 C +ANISOU 5506 CD GLN B 322 7080 8411 5992 -417 622 369 C +ATOM 5507 OE1 GLN B 322 50.166 22.498 46.510 1.00 58.40 O +ANISOU 5507 OE1 GLN B 322 7274 8608 6306 -542 724 418 O +ATOM 5508 NE2 GLN B 322 48.243 21.656 47.366 1.00 54.81 N +ANISOU 5508 NE2 GLN B 322 7002 8136 5686 -351 526 426 N +ATOM 5509 N GLY B 323 50.926 17.177 48.659 1.00 53.92 N +ANISOU 5509 N GLY B 323 6455 8337 5694 -23 508 60 N +ATOM 5510 CA GLY B 323 50.114 16.331 49.546 1.00 52.37 C +ANISOU 5510 CA GLY B 323 6337 8136 5422 108 370 36 C +ATOM 5511 C GLY B 323 50.329 14.830 49.408 1.00 52.04 C +ANISOU 5511 C GLY B 323 6262 8140 5370 229 424 -6 C +ATOM 5512 O GLY B 323 49.762 14.041 50.166 1.00 50.43 O +ANISOU 5512 O GLY B 323 6113 7927 5120 340 320 -21 O +ATOM 5513 N ILE B 324 51.189 14.437 48.475 1.00 53.65 N +ANISOU 5513 N ILE B 324 6374 8379 5631 206 603 -27 N +ATOM 5514 CA ILE B 324 51.418 13.042 48.179 1.00 54.17 C +ANISOU 5514 CA ILE B 324 6417 8460 5703 314 705 -75 C +ATOM 5515 C ILE B 324 52.169 12.387 49.341 1.00 54.58 C +ANISOU 5515 C ILE B 324 6288 8524 5924 443 590 -103 C +ATOM 5516 O ILE B 324 51.882 11.248 49.699 1.00 53.73 O +ANISOU 5516 O ILE B 324 6212 8398 5802 572 568 -119 O +ATOM 5517 CB ILE B 324 52.194 12.857 46.854 1.00 56.00 C +ANISOU 5517 CB ILE B 324 6600 8716 5961 247 963 -102 C +ATOM 5518 CG1 ILE B 324 51.408 13.433 45.664 1.00 55.99 C +ANISOU 5518 CG1 ILE B 324 6800 8719 5752 110 1062 -55 C +ATOM 5519 CG2 ILE B 324 52.508 11.387 46.608 1.00 56.93 C +ANISOU 5519 CG2 ILE B 324 6688 8823 6120 366 1096 -171 C +ATOM 5520 CD1 ILE B 324 50.136 12.702 45.297 1.00 54.73 C +ANISOU 5520 CD1 ILE B 324 6861 8554 5380 133 1046 -52 C +ATOM 5521 N ASP B 325 53.113 13.114 49.940 1.00 55.64 N +ANISOU 5521 N ASP B 325 6235 8689 6217 400 506 -99 N +ATOM 5522 CA ASP B 325 53.898 12.608 51.059 1.00 56.05 C +ANISOU 5522 CA ASP B 325 6094 8775 6427 503 363 -103 C +ATOM 5523 C ASP B 325 52.993 12.418 52.262 1.00 53.85 C +ANISOU 5523 C ASP B 325 5944 8482 6034 571 143 -87 C +ATOM 5524 O ASP B 325 53.079 11.430 52.980 1.00 53.31 O +ANISOU 5524 O ASP B 325 5832 8420 6001 706 58 -73 O +ATOM 5525 CB ASP B 325 54.986 13.606 51.430 1.00 58.42 C +ANISOU 5525 CB ASP B 325 6181 9123 6893 397 294 -103 C +ATOM 5526 CG ASP B 325 55.897 13.965 50.262 1.00 61.16 C +ANISOU 5526 CG ASP B 325 6394 9481 7360 305 524 -115 C +ATOM 5527 OD1 ASP B 325 56.525 13.020 49.727 1.00 63.51 O +ANISOU 5527 OD1 ASP B 325 6575 9787 7769 394 685 -128 O +ATOM 5528 OD2 ASP B 325 55.973 15.179 49.887 1.00 61.95 O +ANISOU 5528 OD2 ASP B 325 6515 9572 7451 145 559 -109 O +ATOM 5529 N ILE B 326 52.116 13.385 52.474 1.00 51.93 N +ANISOU 5529 N ILE B 326 5861 8208 5660 479 67 -82 N +ATOM 5530 CA ILE B 326 51.223 13.314 53.597 1.00 50.40 C +ANISOU 5530 CA ILE B 326 5799 7994 5354 528 -109 -76 C +ATOM 5531 C ILE B 326 50.282 12.128 53.426 1.00 49.36 C +ANISOU 5531 C ILE B 326 5814 7828 5111 648 -64 -63 C +ATOM 5532 O ILE B 326 50.114 11.369 54.370 1.00 49.49 O +ANISOU 5532 O ILE B 326 5842 7847 5112 754 -179 -51 O +ATOM 5533 CB ILE B 326 50.480 14.643 53.799 1.00 49.10 C +ANISOU 5533 CB ILE B 326 5768 7782 5104 407 -160 -80 C +ATOM 5534 CG1 ILE B 326 51.463 15.744 54.183 1.00 50.37 C +ANISOU 5534 CG1 ILE B 326 5784 7965 5387 281 -223 -109 C +ATOM 5535 CG2 ILE B 326 49.470 14.507 54.907 1.00 47.90 C +ANISOU 5535 CG2 ILE B 326 5767 7599 4832 461 -302 -83 C +ATOM 5536 CD1 ILE B 326 50.948 17.128 53.860 1.00 50.04 C +ANISOU 5536 CD1 ILE B 326 5851 7846 5314 144 -179 -107 C +ATOM 5537 N GLU B 327 49.694 11.958 52.236 1.00 49.41 N +ANISOU 5537 N GLU B 327 5933 7806 5033 620 97 -60 N +ATOM 5538 CA GLU B 327 48.831 10.791 51.916 1.00 48.73 C +ANISOU 5538 CA GLU B 327 5985 7687 4843 706 158 -62 C +ATOM 5539 C GLU B 327 49.594 9.493 52.199 1.00 50.11 C +ANISOU 5539 C GLU B 327 6042 7861 5136 843 189 -78 C +ATOM 5540 O GLU B 327 49.137 8.620 52.935 1.00 48.96 O +ANISOU 5540 O GLU B 327 5953 7686 4963 951 112 -63 O +ATOM 5541 CB GLU B 327 48.359 10.791 50.436 1.00 48.11 C +ANISOU 5541 CB GLU B 327 6017 7601 4660 624 336 -67 C +ATOM 5542 CG GLU B 327 47.347 9.672 50.130 1.00 47.42 C +ANISOU 5542 CG GLU B 327 6088 7480 4447 678 381 -80 C +ATOM 5543 CD GLU B 327 46.928 9.489 48.648 1.00 47.45 C +ANISOU 5543 CD GLU B 327 6211 7496 4321 581 547 -96 C +ATOM 5544 OE1 GLU B 327 45.832 8.924 48.398 1.00 46.03 O +ANISOU 5544 OE1 GLU B 327 6184 7298 4004 575 542 -96 O +ATOM 5545 OE2 GLU B 327 47.685 9.867 47.724 1.00 48.70 O +ANISOU 5545 OE2 GLU B 327 6314 7686 4502 499 686 -111 O +ATOM 5546 N ARG B 328 50.764 9.385 51.604 1.00 52.79 N +ANISOU 5546 N ARG B 328 6211 8223 5622 840 313 -99 N +ATOM 5547 CA ARG B 328 51.544 8.178 51.729 1.00 55.58 C +ANISOU 5547 CA ARG B 328 6431 8558 6129 980 378 -105 C +ATOM 5548 C ARG B 328 51.898 7.901 53.204 1.00 56.06 C +ANISOU 5548 C ARG B 328 6381 8641 6277 1087 155 -47 C +ATOM 5549 O ARG B 328 51.869 6.741 53.628 1.00 57.13 O +ANISOU 5549 O ARG B 328 6512 8732 6459 1229 146 -20 O +ATOM 5550 CB ARG B 328 52.775 8.261 50.812 1.00 58.28 C +ANISOU 5550 CB ARG B 328 6585 8919 6636 948 572 -136 C +ATOM 5551 CG ARG B 328 53.772 7.130 50.968 1.00 61.27 C +ANISOU 5551 CG ARG B 328 6768 9269 7240 1104 652 -131 C +ATOM 5552 CD ARG B 328 54.742 7.056 49.805 1.00 64.58 C +ANISOU 5552 CD ARG B 328 7053 9683 7799 1071 924 -185 C +ATOM 5553 NE ARG B 328 56.101 6.778 50.286 1.00 67.79 N +ANISOU 5553 NE ARG B 328 7143 10111 8503 1174 911 -143 N +ATOM 5554 CZ ARG B 328 56.930 7.702 50.780 1.00 69.38 C +ANISOU 5554 CZ ARG B 328 7132 10398 8830 1110 776 -100 C +ATOM 5555 NH1 ARG B 328 56.549 8.978 50.866 1.00 68.68 N +ANISOU 5555 NH1 ARG B 328 7130 10363 8601 945 661 -104 N +ATOM 5556 NH2 ARG B 328 58.148 7.352 51.196 1.00 72.18 N +ANISOU 5556 NH2 ARG B 328 7177 10779 9469 1208 754 -50 N +ATOM 5557 N ALA B 329 52.184 8.952 53.981 1.00 55.56 N +ANISOU 5557 N ALA B 329 6247 8640 6220 1009 -22 -27 N +ATOM 5558 CA ALA B 329 52.558 8.806 55.394 1.00 55.58 C +ANISOU 5558 CA ALA B 329 6156 8690 6270 1076 -255 27 C +ATOM 5559 C ALA B 329 51.404 8.301 56.252 1.00 53.91 C +ANISOU 5559 C ALA B 329 6153 8441 5888 1141 -370 54 C +ATOM 5560 O ALA B 329 51.574 7.408 57.094 1.00 54.80 O +ANISOU 5560 O ALA B 329 6227 8555 6037 1265 -474 117 O +ATOM 5561 CB ALA B 329 53.083 10.130 55.944 1.00 56.06 C +ANISOU 5561 CB ALA B 329 6123 8825 6351 937 -403 15 C +ATOM 5562 N LEU B 330 50.232 8.870 56.043 1.00 52.12 N +ANISOU 5562 N LEU B 330 6137 8179 5488 1059 -346 19 N +ATOM 5563 CA LEU B 330 49.046 8.426 56.756 1.00 51.76 C +ANISOU 5563 CA LEU B 330 6287 8090 5287 1109 -420 39 C +ATOM 5564 C LEU B 330 48.711 6.962 56.451 1.00 52.03 C +ANISOU 5564 C LEU B 330 6377 8057 5334 1241 -316 59 C +ATOM 5565 O LEU B 330 48.360 6.200 57.346 1.00 52.85 O +ANISOU 5565 O LEU B 330 6542 8138 5400 1336 -405 109 O +ATOM 5566 CB LEU B 330 47.852 9.324 56.409 1.00 49.82 C +ANISOU 5566 CB LEU B 330 6225 7809 4893 1000 -384 5 C +ATOM 5567 CG LEU B 330 47.904 10.766 56.915 1.00 49.39 C +ANISOU 5567 CG LEU B 330 6171 7780 4813 876 -483 -18 C +ATOM 5568 CD1 LEU B 330 46.901 11.644 56.187 1.00 47.77 C +ANISOU 5568 CD1 LEU B 330 6101 7522 4525 782 -394 -31 C +ATOM 5569 CD2 LEU B 330 47.639 10.787 58.412 1.00 50.25 C +ANISOU 5569 CD2 LEU B 330 6346 7905 4840 898 -660 -10 C +ATOM 5570 N LYS B 331 48.831 6.569 55.192 1.00 52.92 N +ANISOU 5570 N LYS B 331 6478 8133 5494 1236 -117 19 N +ATOM 5571 CA LYS B 331 48.504 5.197 54.786 1.00 52.95 C +ANISOU 5571 CA LYS B 331 6551 8053 5513 1338 12 12 C +ATOM 5572 C LYS B 331 49.467 4.145 55.280 1.00 55.56 C +ANISOU 5572 C LYS B 331 6726 8356 6027 1495 6 65 C +ATOM 5573 O LYS B 331 49.068 2.998 55.441 1.00 55.35 O +ANISOU 5573 O LYS B 331 6778 8242 6007 1599 54 85 O +ATOM 5574 CB LYS B 331 48.356 5.096 53.268 1.00 52.14 C +ANISOU 5574 CB LYS B 331 6505 7922 5383 1263 237 -63 C +ATOM 5575 CG LYS B 331 46.976 5.529 52.833 1.00 50.32 C +ANISOU 5575 CG LYS B 331 6482 7686 4950 1153 240 -83 C +ATOM 5576 CD LYS B 331 46.850 5.828 51.358 1.00 50.13 C +ANISOU 5576 CD LYS B 331 6515 7676 4856 1031 411 -139 C +ATOM 5577 CE LYS B 331 45.593 6.645 51.131 1.00 48.42 C +ANISOU 5577 CE LYS B 331 6451 7482 4463 917 343 -114 C +ATOM 5578 NZ LYS B 331 44.977 6.397 49.806 1.00 48.42 N +ANISOU 5578 NZ LYS B 331 6579 7485 4333 814 480 -152 N +ATOM 5579 N MET B 332 50.715 4.514 55.544 1.00 59.40 N +ANISOU 5579 N MET B 332 6983 8908 6675 1514 -56 98 N +ATOM 5580 CA MET B 332 51.703 3.515 55.941 1.00 63.31 C +ANISOU 5580 CA MET B 332 7292 9376 7385 1678 -60 171 C +ATOM 5581 C MET B 332 51.857 3.318 57.459 1.00 62.77 C +ANISOU 5581 C MET B 332 7178 9356 7317 1761 -323 292 C +ATOM 5582 O MET B 332 52.652 2.501 57.879 1.00 64.88 O +ANISOU 5582 O MET B 332 7281 9605 7764 1905 -359 387 O +ATOM 5583 CB MET B 332 53.055 3.801 55.266 1.00 68.00 C +ANISOU 5583 CB MET B 332 7626 10009 8201 1671 48 154 C +ATOM 5584 CG MET B 332 53.841 4.974 55.840 1.00 71.95 C +ANISOU 5584 CG MET B 332 7948 10640 8748 1578 -140 184 C +ATOM 5585 SD MET B 332 55.303 5.431 54.849 1.00 79.55 S +ANISOU 5585 SD MET B 332 8614 11643 9966 1533 32 148 S +ATOM 5586 CE MET B 332 56.356 4.003 55.124 1.00 81.07 C +ANISOU 5586 CE MET B 332 8552 11780 10471 1769 80 247 C +ATOM 5587 N VAL B 333 51.100 4.025 58.286 1.00 60.88 N +ANISOU 5587 N VAL B 333 7083 9171 6876 1674 -499 297 N +ATOM 5588 CA VAL B 333 51.283 3.882 59.739 1.00 61.63 C +ANISOU 5588 CA VAL B 333 7153 9327 6934 1728 -749 407 C +ATOM 5589 C VAL B 333 50.816 2.503 60.216 1.00 62.02 C +ANISOU 5589 C VAL B 333 7301 9281 6983 1886 -738 498 C +ATOM 5590 O VAL B 333 49.878 1.931 59.663 1.00 61.22 O +ANISOU 5590 O VAL B 333 7375 9069 6814 1902 -575 448 O +ATOM 5591 CB VAL B 333 50.565 4.981 60.564 1.00 60.01 C +ANISOU 5591 CB VAL B 333 7105 9194 6501 1586 -915 373 C +ATOM 5592 CG1 VAL B 333 50.879 6.375 60.022 1.00 59.85 C +ANISOU 5592 CG1 VAL B 333 7022 9234 6483 1421 -897 277 C +ATOM 5593 CG2 VAL B 333 49.058 4.749 60.603 1.00 57.85 C +ANISOU 5593 CG2 VAL B 333 7107 8837 6035 1574 -843 339 C +ATOM 5594 N GLN B 334 51.512 1.961 61.209 1.00 64.00 N +ANISOU 5594 N GLN B 334 7427 9570 7317 1996 -912 640 N +ATOM 5595 CA GLN B 334 51.037 0.807 61.972 1.00 64.34 C +ANISOU 5595 CA GLN B 334 7584 9535 7325 2132 -957 759 C +ATOM 5596 C GLN B 334 51.067 1.206 63.435 1.00 64.40 C +ANISOU 5596 C GLN B 334 7627 9667 7173 2093 -1249 860 C +ATOM 5597 O GLN B 334 52.135 1.356 64.007 1.00 66.48 O +ANISOU 5597 O GLN B 334 7683 10040 7534 2116 -1436 959 O +ATOM 5598 CB GLN B 334 51.904 -0.441 61.750 1.00 66.88 C +ANISOU 5598 CB GLN B 334 7721 9763 7927 2331 -873 872 C +ATOM 5599 CG GLN B 334 51.489 -1.622 62.630 1.00 67.88 C +ANISOU 5599 CG GLN B 334 7958 9800 8032 2475 -934 1025 C +ATOM 5600 CD GLN B 334 52.201 -2.919 62.312 1.00 70.46 C +ANISOU 5600 CD GLN B 334 8128 9984 8657 2685 -803 1131 C +ATOM 5601 OE1 GLN B 334 53.203 -2.949 61.588 1.00 72.36 O +ANISOU 5601 OE1 GLN B 334 8132 10213 9147 2740 -695 1112 O +ATOM 5602 NE2 GLN B 334 51.671 -4.014 62.847 1.00 71.24 N +ANISOU 5602 NE2 GLN B 334 8363 9957 8745 2804 -790 1245 N +ATOM 5603 N VAL B 335 49.893 1.404 64.026 1.00 62.73 N +ANISOU 5603 N VAL B 335 7675 9446 6711 2021 -1284 831 N +ATOM 5604 CA VAL B 335 49.787 1.796 65.419 1.00 63.93 C +ANISOU 5604 CA VAL B 335 7914 9711 6664 1961 -1530 904 C +ATOM 5605 C VAL B 335 48.722 0.993 66.148 1.00 63.64 C +ANISOU 5605 C VAL B 335 8120 9596 6463 2017 -1520 977 C +ATOM 5606 O VAL B 335 47.760 0.500 65.534 1.00 62.80 O +ANISOU 5606 O VAL B 335 8157 9355 6346 2043 -1317 918 O +ATOM 5607 CB VAL B 335 49.469 3.296 65.586 1.00 63.29 C +ANISOU 5607 CB VAL B 335 7914 9724 6407 1757 -1593 762 C +ATOM 5608 CG1 VAL B 335 50.644 4.145 65.103 1.00 64.82 C +ANISOU 5608 CG1 VAL B 335 7859 10013 6754 1683 -1645 712 C +ATOM 5609 CG2 VAL B 335 48.178 3.676 64.867 1.00 60.70 C +ANISOU 5609 CG2 VAL B 335 7788 9297 5976 1684 -1386 623 C +ATOM 5610 N GLN B 336 48.914 0.861 67.462 1.00 64.90 N +ANISOU 5610 N GLN B 336 8323 9847 6490 2024 -1745 1109 N +ATOM 5611 CA GLN B 336 47.923 0.250 68.344 1.00 64.05 C +ANISOU 5611 CA GLN B 336 8463 9688 6185 2048 -1755 1186 C +ATOM 5612 C GLN B 336 47.060 1.356 68.955 1.00 61.72 C +ANISOU 5612 C GLN B 336 8378 9462 5609 1865 -1793 1062 C +ATOM 5613 O GLN B 336 47.568 2.345 69.474 1.00 62.08 O +ANISOU 5613 O GLN B 336 8383 9646 5556 1741 -1959 1017 O +ATOM 5614 CB GLN B 336 48.599 -0.608 69.420 1.00 66.95 C +ANISOU 5614 CB GLN B 336 8776 10108 6555 2164 -1965 1423 C +ATOM 5615 CG GLN B 336 49.511 -1.679 68.846 1.00 68.96 C +ANISOU 5615 CG GLN B 336 8797 10275 7130 2363 -1917 1557 C +ATOM 5616 CD GLN B 336 48.825 -2.572 67.809 1.00 68.30 C +ANISOU 5616 CD GLN B 336 8785 9973 7192 2462 -1613 1497 C +ATOM 5617 OE1 GLN B 336 47.842 -3.260 68.121 1.00 68.40 O +ANISOU 5617 OE1 GLN B 336 9013 9876 7098 2491 -1525 1534 O +ATOM 5618 NE2 GLN B 336 49.343 -2.570 66.567 1.00 67.60 N +ANISOU 5618 NE2 GLN B 336 8520 9822 7341 2498 -1445 1398 N +ATOM 5619 N GLY B 337 45.750 1.191 68.849 1.00 58.94 N +ANISOU 5619 N GLY B 337 8243 9002 5147 1845 -1623 997 N +ATOM 5620 CA GLY B 337 44.816 2.199 69.302 1.00 57.55 C +ANISOU 5620 CA GLY B 337 8260 8855 4748 1690 -1600 871 C +ATOM 5621 C GLY B 337 43.683 1.549 70.040 1.00 57.31 C +ANISOU 5621 C GLY B 337 8469 8753 4552 1711 -1532 928 C +ATOM 5622 O GLY B 337 43.700 0.353 70.296 1.00 57.70 O +ANISOU 5622 O GLY B 337 8539 8740 4643 1836 -1531 1077 O +ATOM 5623 N MET B 338 42.677 2.341 70.371 1.00 56.62 N +ANISOU 5623 N MET B 338 8559 8659 4293 1590 -1456 812 N +ATOM 5624 CA MET B 338 41.507 1.811 71.040 1.00 57.09 C +ANISOU 5624 CA MET B 338 8843 8646 4202 1594 -1357 851 C +ATOM 5625 C MET B 338 40.753 0.800 70.188 1.00 56.45 C +ANISOU 5625 C MET B 338 8771 8409 4267 1691 -1161 875 C +ATOM 5626 O MET B 338 40.002 -0.010 70.732 1.00 58.04 O +ANISOU 5626 O MET B 338 9123 8538 4391 1728 -1092 957 O +ATOM 5627 CB MET B 338 40.567 2.937 71.419 1.00 56.77 C +ANISOU 5627 CB MET B 338 8962 8612 3996 1450 -1275 703 C +ATOM 5628 CG MET B 338 41.104 3.890 72.486 1.00 59.18 C +ANISOU 5628 CG MET B 338 9332 9054 4099 1323 -1445 659 C +ATOM 5629 SD MET B 338 39.848 5.139 72.879 1.00 59.13 S +ANISOU 5629 SD MET B 338 9530 9000 3935 1169 -1275 470 S +ATOM 5630 CE MET B 338 38.861 4.230 74.076 1.00 60.26 C +ANISOU 5630 CE MET B 338 9931 9106 3855 1189 -1203 573 C +ATOM 5631 N THR B 339 40.937 0.837 68.863 1.00 54.82 N +ANISOU 5631 N THR B 339 8416 8151 4260 1717 -1065 801 N +ATOM 5632 CA THR B 339 40.290 -0.122 67.982 1.00 53.79 C +ANISOU 5632 CA THR B 339 8295 7880 4262 1785 -885 805 C +ATOM 5633 C THR B 339 41.258 -1.168 67.417 1.00 54.20 C +ANISOU 5633 C THR B 339 8199 7879 4513 1920 -889 893 C +ATOM 5634 O THR B 339 41.148 -1.560 66.266 1.00 53.87 O +ANISOU 5634 O THR B 339 8096 7750 4621 1944 -746 831 O +ATOM 5635 CB THR B 339 39.486 0.588 66.846 1.00 52.61 C +ANISOU 5635 CB THR B 339 8132 7692 4163 1696 -735 652 C +ATOM 5636 OG1 THR B 339 40.360 1.285 65.940 1.00 51.95 O +ANISOU 5636 OG1 THR B 339 7878 7666 4193 1673 -765 579 O +ATOM 5637 CG2 THR B 339 38.488 1.571 67.463 1.00 51.93 C +ANISOU 5637 CG2 THR B 339 8182 7632 3917 1585 -709 581 C +ATOM 5638 N GLY B 340 42.191 -1.630 68.242 1.00 55.61 N +ANISOU 5638 N GLY B 340 8325 8108 4695 2006 -1049 1041 N +ATOM 5639 CA GLY B 340 43.111 -2.703 67.874 1.00 56.33 C +ANISOU 5639 CA GLY B 340 8271 8130 5001 2160 -1048 1155 C +ATOM 5640 C GLY B 340 44.244 -2.218 67.002 1.00 56.10 C +ANISOU 5640 C GLY B 340 8005 8159 5151 2174 -1073 1094 C +ATOM 5641 O GLY B 340 44.546 -1.031 66.992 1.00 56.22 O +ANISOU 5641 O GLY B 340 7961 8300 5100 2065 -1162 1004 O +ATOM 5642 N ASN B 341 44.876 -3.153 66.294 1.00 56.26 N +ANISOU 5642 N ASN B 341 7893 8076 5406 2304 -979 1141 N +ATOM 5643 CA ASN B 341 45.892 -2.851 65.299 1.00 55.83 C +ANISOU 5643 CA ASN B 341 7613 8045 5551 2325 -938 1073 C +ATOM 5644 C ASN B 341 45.281 -1.989 64.185 1.00 53.12 C +ANISOU 5644 C ASN B 341 7309 7708 5166 2184 -792 868 C +ATOM 5645 O ASN B 341 44.212 -2.312 63.666 1.00 51.06 O +ANISOU 5645 O ASN B 341 7197 7348 4856 2144 -632 792 O +ATOM 5646 CB ASN B 341 46.433 -4.153 64.711 1.00 57.10 C +ANISOU 5646 CB ASN B 341 7674 8049 5971 2493 -796 1143 C +ATOM 5647 CG ASN B 341 47.481 -3.927 63.623 1.00 57.81 C +ANISOU 5647 CG ASN B 341 7532 8148 6284 2519 -706 1064 C +ATOM 5648 OD1 ASN B 341 48.590 -3.446 63.895 1.00 59.44 O +ANISOU 5648 OD1 ASN B 341 7532 8473 6579 2543 -858 1127 O +ATOM 5649 ND2 ASN B 341 47.143 -4.298 62.384 1.00 56.68 N +ANISOU 5649 ND2 ASN B 341 7423 7880 6229 2504 -456 927 N +ATOM 5650 N ILE B 342 45.967 -0.894 63.841 1.00 52.66 N +ANISOU 5650 N ILE B 342 7112 7769 5128 2104 -857 794 N +ATOM 5651 CA ILE B 342 45.512 0.045 62.820 1.00 50.24 C +ANISOU 5651 CA ILE B 342 6826 7480 4782 1970 -743 630 C +ATOM 5652 C ILE B 342 46.519 0.105 61.683 1.00 50.08 C +ANISOU 5652 C ILE B 342 6608 7459 4960 1991 -642 574 C +ATOM 5653 O ILE B 342 47.644 0.577 61.861 1.00 51.00 O +ANISOU 5653 O ILE B 342 6536 7670 5171 2000 -752 607 O +ATOM 5654 CB ILE B 342 45.355 1.463 63.399 1.00 50.12 C +ANISOU 5654 CB ILE B 342 6844 7592 4604 1831 -884 578 C +ATOM 5655 CG1 ILE B 342 44.298 1.473 64.514 1.00 50.19 C +ANISOU 5655 CG1 ILE B 342 7065 7598 4406 1798 -948 612 C +ATOM 5656 CG2 ILE B 342 44.935 2.456 62.321 1.00 48.36 C +ANISOU 5656 CG2 ILE B 342 6630 7377 4366 1705 -769 437 C +ATOM 5657 CD1 ILE B 342 44.446 2.637 65.472 1.00 50.58 C +ANISOU 5657 CD1 ILE B 342 7143 7771 4304 1689 -1118 591 C +ATOM 5658 N GLN B 343 46.108 -0.389 60.515 1.00 48.77 N +ANISOU 5658 N GLN B 343 6488 7190 4851 1986 -427 487 N +ATOM 5659 CA GLN B 343 46.866 -0.238 59.271 1.00 48.80 C +ANISOU 5659 CA GLN B 343 6350 7189 5000 1969 -281 402 C +ATOM 5660 C GLN B 343 45.898 -0.026 58.139 1.00 46.53 C +ANISOU 5660 C GLN B 343 6204 6862 4612 1849 -115 273 C +ATOM 5661 O GLN B 343 44.724 -0.404 58.213 1.00 44.49 O +ANISOU 5661 O GLN B 343 6125 6543 4235 1818 -79 258 O +ATOM 5662 CB GLN B 343 47.658 -1.502 58.916 1.00 50.74 C +ANISOU 5662 CB GLN B 343 6485 7319 5474 2125 -148 446 C +ATOM 5663 CG GLN B 343 48.706 -1.933 59.904 1.00 53.14 C +ANISOU 5663 CG GLN B 343 6613 7646 5930 2275 -301 606 C +ATOM 5664 CD GLN B 343 49.253 -3.304 59.559 1.00 55.25 C +ANISOU 5664 CD GLN B 343 6800 7752 6438 2448 -137 659 C +ATOM 5665 OE1 GLN B 343 48.894 -4.306 60.185 1.00 56.09 O +ANISOU 5665 OE1 GLN B 343 6996 7751 6564 2557 -146 762 O +ATOM 5666 NE2 GLN B 343 50.124 -3.358 58.556 1.00 56.25 N +ANISOU 5666 NE2 GLN B 343 6761 7849 6760 2473 34 588 N +ATOM 5667 N PHE B 344 46.434 0.498 57.049 1.00 46.66 N +ANISOU 5667 N PHE B 344 6129 6913 4685 1780 -6 188 N +ATOM 5668 CA PHE B 344 45.621 0.797 55.887 1.00 45.48 C +ANISOU 5668 CA PHE B 344 6102 6751 4425 1649 132 79 C +ATOM 5669 C PHE B 344 46.234 0.211 54.631 1.00 46.84 C +ANISOU 5669 C PHE B 344 6221 6864 4710 1654 355 -3 C +ATOM 5670 O PHE B 344 47.425 -0.028 54.579 1.00 48.70 O +ANISOU 5670 O PHE B 344 6282 7093 5128 1742 402 15 O +ATOM 5671 CB PHE B 344 45.461 2.303 55.717 1.00 43.86 C +ANISOU 5671 CB PHE B 344 5886 6660 4116 1511 48 53 C +ATOM 5672 CG PHE B 344 44.977 3.001 56.936 1.00 42.76 C +ANISOU 5672 CG PHE B 344 5795 6573 3877 1496 -144 111 C +ATOM 5673 CD1 PHE B 344 43.614 3.103 57.192 1.00 41.15 C +ANISOU 5673 CD1 PHE B 344 5763 6344 3526 1444 -165 110 C +ATOM 5674 CD2 PHE B 344 45.885 3.582 57.820 1.00 43.37 C +ANISOU 5674 CD2 PHE B 344 5742 6728 4009 1520 -298 161 C +ATOM 5675 CE1 PHE B 344 43.164 3.776 58.312 1.00 40.41 C +ANISOU 5675 CE1 PHE B 344 5724 6288 3341 1425 -309 148 C +ATOM 5676 CE2 PHE B 344 45.439 4.253 58.944 1.00 42.95 C +ANISOU 5676 CE2 PHE B 344 5758 6720 3839 1483 -460 192 C +ATOM 5677 CZ PHE B 344 44.078 4.342 59.195 1.00 41.43 C +ANISOU 5677 CZ PHE B 344 5750 6488 3501 1441 -452 181 C +ATOM 5678 N ASP B 345 45.395 -0.020 53.630 1.00 46.67 N +ANISOU 5678 N ASP B 345 6350 6803 4576 1551 494 -95 N +ATOM 5679 CA ASP B 345 45.850 -0.393 52.310 1.00 48.42 C +ANISOU 5679 CA ASP B 345 6566 6987 4844 1505 722 -202 C +ATOM 5680 C ASP B 345 45.944 0.877 51.468 1.00 47.48 C +ANISOU 5680 C ASP B 345 6427 6988 4625 1352 727 -241 C +ATOM 5681 O ASP B 345 45.726 1.963 51.969 1.00 46.08 O +ANISOU 5681 O ASP B 345 6225 6900 4380 1304 561 -184 O +ATOM 5682 CB ASP B 345 44.865 -1.391 51.690 1.00 49.48 C +ANISOU 5682 CB ASP B 345 6896 7018 4886 1451 859 -284 C +ATOM 5683 CG ASP B 345 43.555 -0.739 51.249 1.00 48.80 C +ANISOU 5683 CG ASP B 345 6965 7006 4569 1278 792 -309 C +ATOM 5684 OD1 ASP B 345 43.440 0.502 51.307 1.00 49.53 O +ANISOU 5684 OD1 ASP B 345 7020 7215 4584 1206 668 -265 O +ATOM 5685 OD2 ASP B 345 42.633 -1.469 50.844 1.00 49.54 O +ANISOU 5685 OD2 ASP B 345 7212 7036 4572 1212 862 -366 O +ATOM 5686 N THR B 346 46.225 0.722 50.184 1.00 48.32 N +ANISOU 5686 N THR B 346 6560 7084 4712 1269 932 -341 N +ATOM 5687 CA THR B 346 46.461 1.841 49.281 1.00 48.00 C +ANISOU 5687 CA THR B 346 6499 7150 4587 1126 969 -367 C +ATOM 5688 C THR B 346 45.235 2.742 49.038 1.00 46.18 C +ANISOU 5688 C THR B 346 6410 6998 4136 977 847 -338 C +ATOM 5689 O THR B 346 45.401 3.880 48.640 1.00 45.74 O +ANISOU 5689 O THR B 346 6318 7029 4029 881 814 -311 O +ATOM 5690 CB THR B 346 47.006 1.339 47.914 1.00 49.79 C +ANISOU 5690 CB THR B 346 6755 7343 4818 1060 1246 -487 C +ATOM 5691 OG1 THR B 346 47.439 2.453 47.121 1.00 50.09 O +ANISOU 5691 OG1 THR B 346 6750 7486 4796 933 1288 -491 O +ATOM 5692 CG2 THR B 346 45.948 0.584 47.127 1.00 49.51 C +ANISOU 5692 CG2 THR B 346 6948 7261 4602 953 1347 -578 C +ATOM 5693 N TYR B 347 44.020 2.243 49.259 1.00 45.12 N +ANISOU 5693 N TYR B 347 6424 6828 3889 958 786 -333 N +ATOM 5694 CA TYR B 347 42.826 3.080 49.158 1.00 43.93 C +ANISOU 5694 CA TYR B 347 6372 6746 3571 841 657 -282 C +ATOM 5695 C TYR B 347 42.342 3.618 50.498 1.00 42.28 C +ANISOU 5695 C TYR B 347 6133 6542 3388 913 459 -188 C +ATOM 5696 O TYR B 347 41.195 4.042 50.616 1.00 40.57 O +ANISOU 5696 O TYR B 347 5999 6347 3067 851 366 -144 O +ATOM 5697 CB TYR B 347 41.692 2.328 48.460 1.00 44.50 C +ANISOU 5697 CB TYR B 347 6617 6795 3496 741 711 -334 C +ATOM 5698 CG TYR B 347 42.116 1.826 47.111 1.00 46.37 C +ANISOU 5698 CG TYR B 347 6918 7031 3668 640 915 -445 C +ATOM 5699 CD1 TYR B 347 42.444 2.724 46.085 1.00 46.88 C +ANISOU 5699 CD1 TYR B 347 6981 7194 3635 511 964 -445 C +ATOM 5700 CD2 TYR B 347 42.247 0.457 46.870 1.00 47.71 C +ANISOU 5700 CD2 TYR B 347 7157 7090 3878 672 1078 -554 C +ATOM 5701 CE1 TYR B 347 42.872 2.262 44.842 1.00 49.02 C +ANISOU 5701 CE1 TYR B 347 7330 7470 3825 405 1173 -557 C +ATOM 5702 CE2 TYR B 347 42.672 -0.014 45.631 1.00 49.65 C +ANISOU 5702 CE2 TYR B 347 7480 7325 4059 570 1296 -681 C +ATOM 5703 CZ TYR B 347 42.973 0.884 44.625 1.00 50.31 C +ANISOU 5703 CZ TYR B 347 7571 7522 4020 433 1343 -685 C +ATOM 5704 OH TYR B 347 43.372 0.395 43.407 1.00 53.16 O +ANISOU 5704 OH TYR B 347 8030 7876 4291 318 1576 -819 O +ATOM 5705 N GLY B 348 43.223 3.618 51.492 1.00 42.64 N +ANISOU 5705 N GLY B 348 6055 6572 3572 1037 399 -157 N +ATOM 5706 CA GLY B 348 42.904 4.112 52.807 1.00 42.13 C +ANISOU 5706 CA GLY B 348 5974 6517 3514 1094 224 -84 C +ATOM 5707 C GLY B 348 41.911 3.288 53.601 1.00 41.61 C +ANISOU 5707 C GLY B 348 6018 6385 3405 1152 175 -58 C +ATOM 5708 O GLY B 348 41.291 3.805 54.511 1.00 40.21 O +ANISOU 5708 O GLY B 348 5874 6220 3182 1159 55 -7 O +ATOM 5709 N ARG B 349 41.772 2.018 53.268 1.00 43.40 N +ANISOU 5709 N ARG B 349 6306 6533 3651 1189 286 -99 N +ATOM 5710 CA ARG B 349 40.880 1.126 54.001 1.00 44.51 C +ANISOU 5710 CA ARG B 349 6551 6595 3767 1241 261 -72 C +ATOM 5711 C ARG B 349 41.619 0.373 55.084 1.00 44.57 C +ANISOU 5711 C ARG B 349 6498 6541 3893 1401 225 -16 C +ATOM 5712 O ARG B 349 42.784 0.027 54.913 1.00 44.65 O +ANISOU 5712 O ARG B 349 6395 6533 4034 1479 283 -24 O +ATOM 5713 CB ARG B 349 40.219 0.131 53.050 1.00 47.41 C +ANISOU 5713 CB ARG B 349 7033 6894 4086 1172 401 -148 C +ATOM 5714 CG ARG B 349 39.064 0.753 52.300 1.00 48.91 C +ANISOU 5714 CG ARG B 349 7306 7150 4127 1012 375 -160 C +ATOM 5715 CD ARG B 349 38.326 -0.288 51.490 1.00 52.16 C +ANISOU 5715 CD ARG B 349 7839 7502 4474 923 486 -237 C +ATOM 5716 NE ARG B 349 37.503 0.323 50.446 1.00 54.68 N +ANISOU 5716 NE ARG B 349 8213 7915 4648 748 464 -251 N +ATOM 5717 CZ ARG B 349 37.804 0.375 49.144 1.00 57.07 C +ANISOU 5717 CZ ARG B 349 8548 8266 4867 628 559 -324 C +ATOM 5718 NH1 ARG B 349 38.938 -0.148 48.659 1.00 59.41 N +ANISOU 5718 NH1 ARG B 349 8828 8518 5226 663 716 -412 N +ATOM 5719 NH2 ARG B 349 36.942 0.955 48.306 1.00 58.16 N +ANISOU 5719 NH2 ARG B 349 8737 8502 4858 467 500 -301 N +ATOM 5720 N ARG B 350 40.937 0.127 56.205 1.00 44.04 N +ANISOU 5720 N ARG B 350 6502 6444 3785 1450 131 51 N +ATOM 5721 CA ARG B 350 41.565 -0.608 57.308 1.00 44.81 C +ANISOU 5721 CA ARG B 350 6561 6491 3973 1598 74 134 C +ATOM 5722 C ARG B 350 41.909 -2.001 56.838 1.00 46.12 C +ANISOU 5722 C ARG B 350 6735 6526 4260 1678 228 112 C +ATOM 5723 O ARG B 350 41.113 -2.644 56.176 1.00 45.82 O +ANISOU 5723 O ARG B 350 6813 6411 4183 1615 349 46 O +ATOM 5724 CB ARG B 350 40.648 -0.718 58.520 1.00 43.81 C +ANISOU 5724 CB ARG B 350 6546 6347 3753 1618 -23 209 C +ATOM 5725 CG ARG B 350 40.378 0.588 59.254 1.00 42.71 C +ANISOU 5725 CG ARG B 350 6407 6312 3508 1559 -164 231 C +ATOM 5726 CD ARG B 350 41.516 1.021 60.171 1.00 43.73 C +ANISOU 5726 CD ARG B 350 6430 6514 3672 1624 -307 291 C +ATOM 5727 NE ARG B 350 41.769 0.111 61.307 1.00 45.13 N +ANISOU 5727 NE ARG B 350 6634 6652 3861 1742 -378 399 N +ATOM 5728 CZ ARG B 350 41.228 0.205 62.526 1.00 45.31 C +ANISOU 5728 CZ ARG B 350 6763 6691 3760 1744 -475 462 C +ATOM 5729 NH1 ARG B 350 40.367 1.173 62.819 1.00 44.36 N +ANISOU 5729 NH1 ARG B 350 6730 6612 3510 1641 -498 415 N +ATOM 5730 NH2 ARG B 350 41.553 -0.682 63.467 1.00 46.55 N +ANISOU 5730 NH2 ARG B 350 6943 6816 3926 1850 -541 580 N +ATOM 5731 N THR B 351 43.103 -2.449 57.158 1.00 48.09 N +ANISOU 5731 N THR B 351 6856 6748 4667 1811 226 167 N +ATOM 5732 CA THR B 351 43.468 -3.808 56.873 1.00 50.79 C +ANISOU 5732 CA THR B 351 7200 6936 5160 1916 382 163 C +ATOM 5733 C THR B 351 44.154 -4.386 58.102 1.00 53.47 C +ANISOU 5733 C THR B 351 7458 7236 5620 2091 272 320 C +ATOM 5734 O THR B 351 44.663 -3.654 58.935 1.00 52.68 O +ANISOU 5734 O THR B 351 7262 7255 5499 2118 85 408 O +ATOM 5735 CB THR B 351 44.341 -3.892 55.615 1.00 51.64 C +ANISOU 5735 CB THR B 351 7210 7023 5385 1902 562 56 C +ATOM 5736 OG1 THR B 351 44.302 -5.235 55.106 1.00 53.33 O +ANISOU 5736 OG1 THR B 351 7495 7057 5710 1956 770 1 O +ATOM 5737 CG2 THR B 351 45.789 -3.421 55.902 1.00 52.63 C +ANISOU 5737 CG2 THR B 351 7102 7222 5669 2001 492 123 C +ATOM 5738 N ASN B 352 44.121 -5.702 58.222 1.00 57.68 N +ANISOU 5738 N ASN B 352 8043 7601 6272 2199 384 361 N +ATOM 5739 CA ASN B 352 44.731 -6.406 59.345 1.00 62.43 C +ANISOU 5739 CA ASN B 352 8576 8144 6999 2378 287 541 C +ATOM 5740 C ASN B 352 44.064 -5.988 60.660 1.00 58.95 C +ANISOU 5740 C ASN B 352 8231 7792 6373 2356 74 656 C +ATOM 5741 O ASN B 352 44.732 -5.716 61.668 1.00 59.26 O +ANISOU 5741 O ASN B 352 8175 7921 6419 2433 -117 796 O +ATOM 5742 CB ASN B 352 46.253 -6.176 59.367 1.00 68.99 C +ANISOU 5742 CB ASN B 352 9153 9033 8024 2492 235 606 C +ATOM 5743 CG ASN B 352 47.010 -7.318 60.015 1.00 77.89 C +ANISOU 5743 CG ASN B 352 10184 10032 9378 2705 234 777 C +ATOM 5744 OD1 ASN B 352 46.423 -8.318 60.453 1.00 77.25 O +ANISOU 5744 OD1 ASN B 352 10240 9802 9308 2771 284 850 O +ATOM 5745 ND2 ASN B 352 48.339 -7.163 60.088 1.00 93.61 N +ANISOU 5745 ND2 ASN B 352 11924 12076 11568 2814 175 857 N +ATOM 5746 N TYR B 353 42.735 -5.937 60.624 1.00 55.16 N +ANISOU 5746 N TYR B 353 7940 7293 5726 2238 112 593 N +ATOM 5747 CA TYR B 353 41.931 -5.553 61.787 1.00 53.19 C +ANISOU 5747 CA TYR B 353 7807 7109 5292 2199 -36 675 C +ATOM 5748 C TYR B 353 41.256 -6.778 62.403 1.00 52.83 C +ANISOU 5748 C TYR B 353 7908 6908 5257 2263 26 770 C +ATOM 5749 O TYR B 353 41.265 -7.862 61.827 1.00 53.28 O +ANISOU 5749 O TYR B 353 7990 6795 5456 2316 195 747 O +ATOM 5750 CB TYR B 353 40.875 -4.498 61.418 1.00 50.51 C +ANISOU 5750 CB TYR B 353 7553 6863 4773 2023 -41 555 C +ATOM 5751 CG TYR B 353 39.911 -4.925 60.333 1.00 49.42 C +ANISOU 5751 CG TYR B 353 7514 6636 4627 1922 136 432 C +ATOM 5752 CD1 TYR B 353 38.683 -5.476 60.639 1.00 48.99 C +ANISOU 5752 CD1 TYR B 353 7613 6500 4499 1873 189 441 C +ATOM 5753 CD2 TYR B 353 40.227 -4.731 58.996 1.00 49.84 C +ANISOU 5753 CD2 TYR B 353 7505 6698 4733 1857 246 304 C +ATOM 5754 CE1 TYR B 353 37.810 -5.868 59.658 1.00 48.86 C +ANISOU 5754 CE1 TYR B 353 7675 6416 4473 1762 329 330 C +ATOM 5755 CE2 TYR B 353 39.366 -5.109 57.986 1.00 49.47 C +ANISOU 5755 CE2 TYR B 353 7555 6588 4650 1742 388 189 C +ATOM 5756 CZ TYR B 353 38.155 -5.691 58.325 1.00 49.48 C +ANISOU 5756 CZ TYR B 353 7699 6512 4588 1692 420 202 C +ATOM 5757 OH TYR B 353 37.298 -6.091 57.316 1.00 49.44 O +ANISOU 5757 OH TYR B 353 7781 6455 4547 1557 543 88 O +ATOM 5758 N THR B 354 40.665 -6.576 63.575 1.00 51.82 N +ANISOU 5758 N THR B 354 7886 6829 4972 2248 -94 868 N +ATOM 5759 CA THR B 354 39.924 -7.607 64.268 1.00 52.17 C +ANISOU 5759 CA THR B 354 8085 6739 4995 2288 -39 970 C +ATOM 5760 C THR B 354 38.574 -7.055 64.679 1.00 50.24 C +ANISOU 5760 C THR B 354 7991 6546 4549 2150 -43 924 C +ATOM 5761 O THR B 354 38.467 -5.917 65.123 1.00 48.83 O +ANISOU 5761 O THR B 354 7806 6520 4226 2080 -163 903 O +ATOM 5762 CB THR B 354 40.677 -8.103 65.523 1.00 54.18 C +ANISOU 5762 CB THR B 354 8321 6993 5269 2436 -184 1192 C +ATOM 5763 OG1 THR B 354 41.937 -8.656 65.132 1.00 55.75 O +ANISOU 5763 OG1 THR B 354 8349 7132 5700 2583 -172 1251 O +ATOM 5764 CG2 THR B 354 39.887 -9.192 66.245 1.00 55.34 C +ANISOU 5764 CG2 THR B 354 8645 6989 5391 2473 -112 1313 C +ATOM 5765 N ILE B 355 37.548 -7.882 64.522 1.00 50.19 N +ANISOU 5765 N ILE B 355 8116 6401 4552 2108 102 906 N +ATOM 5766 CA ILE B 355 36.212 -7.585 64.977 1.00 49.34 C +ANISOU 5766 CA ILE B 355 8142 6312 4293 1992 127 887 C +ATOM 5767 C ILE B 355 35.816 -8.581 66.050 1.00 51.58 C +ANISOU 5767 C ILE B 355 8563 6480 4552 2054 156 1043 C +ATOM 5768 O ILE B 355 35.988 -9.769 65.905 1.00 52.63 O +ANISOU 5768 O ILE B 355 8728 6447 4823 2131 255 1101 O +ATOM 5769 CB ILE B 355 35.245 -7.630 63.786 1.00 48.08 C +ANISOU 5769 CB ILE B 355 7999 6102 4164 1857 271 728 C +ATOM 5770 CG1 ILE B 355 35.617 -6.479 62.838 1.00 46.15 C +ANISOU 5770 CG1 ILE B 355 7632 5997 3907 1789 221 602 C +ATOM 5771 CG2 ILE B 355 33.781 -7.588 64.259 1.00 47.73 C +ANISOU 5771 CG2 ILE B 355 8075 6042 4015 1750 324 730 C +ATOM 5772 CD1 ILE B 355 34.624 -6.234 61.763 1.00 45.14 C +ANISOU 5772 CD1 ILE B 355 7516 5875 3761 1638 309 469 C +ATOM 5773 N ASP B 356 35.322 -8.090 67.170 1.00 53.25 N +ANISOU 5773 N ASP B 356 8869 6774 4588 2020 80 1116 N +ATOM 5774 CA ASP B 356 34.955 -8.965 68.271 1.00 55.06 C +ANISOU 5774 CA ASP B 356 9247 6910 4763 2068 105 1281 C +ATOM 5775 C ASP B 356 33.469 -9.271 68.112 1.00 53.84 C +ANISOU 5775 C ASP B 356 9204 6664 4587 1947 275 1214 C +ATOM 5776 O ASP B 356 32.694 -8.387 67.768 1.00 52.30 O +ANISOU 5776 O ASP B 356 8990 6553 4326 1827 298 1089 O +ATOM 5777 CB ASP B 356 35.257 -8.272 69.595 1.00 57.33 C +ANISOU 5777 CB ASP B 356 9591 7347 4845 2081 -62 1391 C +ATOM 5778 CG ASP B 356 36.767 -7.972 69.798 1.00 59.71 C +ANISOU 5778 CG ASP B 356 9759 7756 5172 2187 -260 1470 C +ATOM 5779 OD1 ASP B 356 37.564 -8.932 69.929 1.00 61.93 O +ANISOU 5779 OD1 ASP B 356 9999 7948 5583 2326 -290 1618 O +ATOM 5780 OD2 ASP B 356 37.142 -6.762 69.852 1.00 60.64 O +ANISOU 5780 OD2 ASP B 356 9804 8042 5192 2130 -383 1389 O +ATOM 5781 N VAL B 357 33.068 -10.515 68.331 1.00 54.88 N +ANISOU 5781 N VAL B 357 9440 6616 4795 1976 396 1304 N +ATOM 5782 CA VAL B 357 31.679 -10.915 68.130 1.00 54.97 C +ANISOU 5782 CA VAL B 357 9540 6529 4815 1850 564 1242 C +ATOM 5783 C VAL B 357 31.043 -11.248 69.453 1.00 57.27 C +ANISOU 5783 C VAL B 357 9994 6787 4980 1845 599 1392 C +ATOM 5784 O VAL B 357 31.601 -12.036 70.200 1.00 59.60 O +ANISOU 5784 O VAL B 357 10366 7001 5278 1956 573 1569 O +ATOM 5785 CB VAL B 357 31.584 -12.147 67.226 1.00 55.51 C +ANISOU 5785 CB VAL B 357 9615 6390 5083 1849 717 1197 C +ATOM 5786 CG1 VAL B 357 30.132 -12.558 67.012 1.00 55.01 C +ANISOU 5786 CG1 VAL B 357 9630 6236 5034 1694 876 1129 C +ATOM 5787 CG2 VAL B 357 32.280 -11.888 65.887 1.00 54.86 C +ANISOU 5787 CG2 VAL B 357 9392 6337 5114 1848 706 1043 C +ATOM 5788 N TYR B 358 29.884 -10.658 69.737 1.00 58.33 N +ANISOU 5788 N TYR B 358 10175 6979 5009 1719 665 1332 N +ATOM 5789 CA TYR B 358 29.215 -10.812 71.029 1.00 61.66 C +ANISOU 5789 CA TYR B 358 10757 7388 5281 1695 720 1457 C +ATOM 5790 C TYR B 358 27.876 -11.516 70.926 1.00 63.74 C +ANISOU 5790 C TYR B 358 11088 7511 5618 1585 924 1439 C +ATOM 5791 O TYR B 358 27.070 -11.184 70.084 1.00 62.45 O +ANISOU 5791 O TYR B 358 10834 7358 5535 1472 995 1293 O +ATOM 5792 CB TYR B 358 29.012 -9.448 71.683 1.00 61.61 C +ANISOU 5792 CB TYR B 358 10759 7568 5080 1643 648 1411 C +ATOM 5793 CG TYR B 358 30.278 -8.895 72.274 1.00 62.61 C +ANISOU 5793 CG TYR B 358 10879 7829 5079 1735 444 1480 C +ATOM 5794 CD1 TYR B 358 31.250 -8.355 71.451 1.00 62.40 C +ANISOU 5794 CD1 TYR B 358 10692 7882 5134 1782 313 1396 C +ATOM 5795 CD2 TYR B 358 30.511 -8.909 73.643 1.00 64.53 C +ANISOU 5795 CD2 TYR B 358 11275 8127 5114 1761 380 1629 C +ATOM 5796 CE1 TYR B 358 32.421 -7.843 71.965 1.00 63.62 C +ANISOU 5796 CE1 TYR B 358 10816 8165 5190 1853 119 1457 C +ATOM 5797 CE2 TYR B 358 31.687 -8.405 74.173 1.00 65.71 C +ANISOU 5797 CE2 TYR B 358 11408 8416 5142 1826 168 1693 C +ATOM 5798 CZ TYR B 358 32.636 -7.867 73.322 1.00 65.10 C +ANISOU 5798 CZ TYR B 358 11146 8413 5173 1871 36 1604 C +ATOM 5799 OH TYR B 358 33.817 -7.341 73.783 1.00 66.53 O +ANISOU 5799 OH TYR B 358 11281 8737 5258 1922 -179 1660 O +ATOM 5800 N GLU B 359 27.636 -12.479 71.807 1.00 68.67 N +ANISOU 5800 N GLU B 359 11867 8008 6215 1610 1013 1601 N +ATOM 5801 CA GLU B 359 26.343 -13.139 71.902 1.00 73.06 C +ANISOU 5801 CA GLU B 359 12498 8431 6828 1494 1216 1603 C +ATOM 5802 C GLU B 359 25.701 -12.742 73.220 1.00 77.61 C +ANISOU 5802 C GLU B 359 13212 9074 7202 1452 1274 1696 C +ATOM 5803 O GLU B 359 26.325 -12.878 74.273 1.00 80.76 O +ANISOU 5803 O GLU B 359 13741 9500 7442 1537 1201 1861 O +ATOM 5804 CB GLU B 359 26.510 -14.659 71.850 1.00 75.61 C +ANISOU 5804 CB GLU B 359 12909 8520 7300 1543 1316 1718 C +ATOM 5805 CG GLU B 359 26.793 -15.215 70.465 1.00 75.99 C +ANISOU 5805 CG GLU B 359 12847 8454 7569 1535 1345 1585 C +ATOM 5806 CD GLU B 359 27.105 -16.716 70.456 1.00 79.37 C +ANISOU 5806 CD GLU B 359 13371 8622 8161 1603 1455 1698 C +ATOM 5807 OE1 GLU B 359 27.277 -17.318 71.543 1.00 81.01 O +ANISOU 5807 OE1 GLU B 359 13719 8746 8313 1687 1476 1913 O +ATOM 5808 OE2 GLU B 359 27.186 -17.302 69.342 1.00 81.42 O +ANISOU 5808 OE2 GLU B 359 13574 8754 8606 1569 1529 1571 O +ATOM 5809 N MET B 360 24.461 -12.262 73.178 1.00 80.69 N +ANISOU 5809 N MET B 360 13571 9490 7595 1318 1407 1599 N +ATOM 5810 CA MET B 360 23.722 -11.992 74.408 1.00 85.06 C +ANISOU 5810 CA MET B 360 14265 10076 7976 1265 1522 1675 C +ATOM 5811 C MET B 360 22.514 -12.915 74.517 1.00 86.38 C +ANISOU 5811 C MET B 360 14487 10078 8253 1158 1753 1715 C +ATOM 5812 O MET B 360 22.176 -13.623 73.563 1.00 86.35 O +ANISOU 5812 O MET B 360 14396 9953 8460 1106 1810 1654 O +ATOM 5813 CB MET B 360 23.287 -10.534 74.450 1.00 86.70 C +ANISOU 5813 CB MET B 360 14389 10451 8100 1207 1511 1538 C +ATOM 5814 CG MET B 360 24.420 -9.559 74.184 1.00 88.17 C +ANISOU 5814 CG MET B 360 14498 10792 8209 1288 1291 1472 C +ATOM 5815 SD MET B 360 24.100 -7.887 74.790 1.00 93.39 S +ANISOU 5815 SD MET B 360 15157 11625 8699 1237 1293 1363 S +ATOM 5816 CE MET B 360 24.125 -8.014 76.574 1.00 93.45 C +ANISOU 5816 CE MET B 360 15443 11658 8404 1233 1356 1508 C +ATOM 5817 N SER B 363 19.339 -13.827 80.536 1.00100.25 N +ANISOU 5817 N SER B 363 17178 11706 9204 876 2630 2290 N +ATOM 5818 CA SER B 363 20.429 -12.865 80.625 1.00100.10 C +ANISOU 5818 CA SER B 363 17156 11871 9006 967 2380 2240 C +ATOM 5819 C SER B 363 21.781 -13.531 80.346 1.00100.84 C +ANISOU 5819 C SER B 363 17262 11940 9111 1108 2127 2368 C +ATOM 5820 O SER B 363 22.062 -14.644 80.824 1.00100.91 O +ANISOU 5820 O SER B 363 17421 11825 9095 1152 2141 2580 O +ATOM 5821 CB SER B 363 20.442 -12.185 81.994 1.00101.87 C +ANISOU 5821 CB SER B 363 17604 12225 8876 930 2430 2286 C +ATOM 5822 OG SER B 363 21.156 -10.963 81.936 1.00100.24 O +ANISOU 5822 OG SER B 363 17344 12202 8541 967 2241 2156 O +ATOM 5823 N GLY B 364 22.608 -12.815 79.586 1.00 98.85 N +ANISOU 5823 N GLY B 364 16847 11800 8909 1180 1908 2246 N +ATOM 5824 CA GLY B 364 23.862 -13.329 79.042 1.00 99.52 C +ANISOU 5824 CA GLY B 364 16870 11861 9082 1317 1681 2321 C +ATOM 5825 C GLY B 364 24.478 -12.262 78.149 1.00 98.46 C +ANISOU 5825 C GLY B 364 16532 11870 9008 1353 1499 2133 C +ATOM 5826 O GLY B 364 23.752 -11.474 77.531 1.00 96.79 O +ANISOU 5826 O GLY B 364 16182 11703 8888 1272 1576 1942 O +ATOM 5827 N SER B 365 25.812 -12.216 78.100 1.00 98.59 N +ANISOU 5827 N SER B 365 16521 11958 8978 1474 1259 2199 N +ATOM 5828 CA SER B 365 26.549 -11.173 77.345 1.00 95.17 C +ANISOU 5828 CA SER B 365 15907 11670 8581 1510 1075 2038 C +ATOM 5829 C SER B 365 28.038 -11.531 77.143 1.00 93.92 C +ANISOU 5829 C SER B 365 15691 11534 8459 1657 839 2146 C +ATOM 5830 O SER B 365 28.936 -10.712 77.415 1.00 93.33 O +ANISOU 5830 O SER B 365 15585 11627 8246 1693 640 2134 O +ATOM 5831 CB SER B 365 26.424 -9.792 78.026 1.00 95.39 C +ANISOU 5831 CB SER B 365 15984 11886 8371 1438 1043 1937 C +ATOM 5832 OG SER B 365 27.310 -9.638 79.128 1.00 98.47 O +ANISOU 5832 OG SER B 365 16527 12394 8490 1476 879 2073 O +ATOM 5833 N ARG B 366 28.286 -12.752 76.662 1.00 91.20 N +ANISOU 5833 N ARG B 366 15322 11010 8318 1738 873 2248 N +ATOM 5834 CA ARG B 366 29.649 -13.224 76.418 1.00 88.82 C +ANISOU 5834 CA ARG B 366 14943 10691 8110 1894 687 2363 C +ATOM 5835 C ARG B 366 30.161 -12.873 75.017 1.00 82.83 C +ANISOU 5835 C ARG B 366 13956 9945 7570 1927 630 2176 C +ATOM 5836 O ARG B 366 29.424 -12.855 74.037 1.00 79.09 O +ANISOU 5836 O ARG B 366 13398 9402 7248 1845 765 2003 O +ATOM 5837 CB ARG B 366 29.776 -14.736 76.667 1.00 91.82 C +ANISOU 5837 CB ARG B 366 15422 10850 8615 1985 764 2584 C +ATOM 5838 CG ARG B 366 29.053 -15.637 75.671 1.00 92.23 C +ANISOU 5838 CG ARG B 366 15428 10669 8943 1946 981 2492 C +ATOM 5839 CD ARG B 366 29.233 -17.118 75.996 1.00 95.88 C +ANISOU 5839 CD ARG B 366 16004 10889 9535 2039 1067 2719 C +ATOM 5840 NE ARG B 366 30.500 -17.664 75.491 1.00 97.42 N +ANISOU 5840 NE ARG B 366 16086 11001 9925 2216 952 2800 N +ATOM 5841 CZ ARG B 366 30.696 -18.183 74.271 1.00 97.31 C +ANISOU 5841 CZ ARG B 366 15950 10831 10192 2246 1040 2667 C +ATOM 5842 NH1 ARG B 366 29.705 -18.255 73.383 1.00 96.29 N +ANISOU 5842 NH1 ARG B 366 15794 10618 10173 2098 1221 2448 N +ATOM 5843 NH2 ARG B 366 31.900 -18.649 73.935 1.00 98.25 N +ANISOU 5843 NH2 ARG B 366 15967 10874 10486 2421 950 2755 N +ATOM 5844 N LYS B 367 31.447 -12.574 74.974 1.00 80.18 N +ANISOU 5844 N LYS B 367 13522 9711 7232 2038 419 2224 N +ATOM 5845 CA LYS B 367 32.198 -12.490 73.754 1.00 77.03 C +ANISOU 5845 CA LYS B 367 12921 9298 7047 2102 364 2106 C +ATOM 5846 C LYS B 367 32.291 -13.903 73.191 1.00 75.43 C +ANISOU 5846 C LYS B 367 12715 8846 7098 2186 493 2179 C +ATOM 5847 O LYS B 367 32.960 -14.768 73.751 1.00 76.51 O +ANISOU 5847 O LYS B 367 12900 8888 7281 2318 444 2399 O +ATOM 5848 CB LYS B 367 33.581 -11.931 74.065 1.00 78.76 C +ANISOU 5848 CB LYS B 367 13043 9679 7201 2204 112 2181 C +ATOM 5849 CG LYS B 367 34.474 -11.731 72.865 1.00 79.02 C +ANISOU 5849 CG LYS B 367 12857 9721 7446 2272 55 2063 C +ATOM 5850 CD LYS B 367 35.721 -10.968 73.279 1.00 80.64 C +ANISOU 5850 CD LYS B 367 12956 10119 7562 2336 -198 2123 C +ATOM 5851 CE LYS B 367 36.688 -10.833 72.118 1.00 80.23 C +ANISOU 5851 CE LYS B 367 12677 10067 7737 2412 -238 2024 C +ATOM 5852 NZ LYS B 367 37.723 -9.798 72.404 1.00 81.05 N +ANISOU 5852 NZ LYS B 367 12659 10388 7748 2423 -472 2025 N +ATOM 5853 N ALA B 368 31.598 -14.136 72.086 1.00 71.42 N +ANISOU 5853 N ALA B 368 12153 8227 6755 2102 659 1998 N +ATOM 5854 CA ALA B 368 31.515 -15.463 71.490 1.00 70.76 C +ANISOU 5854 CA ALA B 368 12090 7886 6909 2142 822 2021 C +ATOM 5855 C ALA B 368 32.724 -15.838 70.620 1.00 69.20 C +ANISOU 5855 C ALA B 368 11747 7616 6927 2278 780 1999 C +ATOM 5856 O ALA B 368 32.885 -17.007 70.275 1.00 69.75 O +ANISOU 5856 O ALA B 368 11845 7451 7206 2346 912 2049 O +ATOM 5857 CB ALA B 368 30.223 -15.584 70.691 1.00 69.55 C +ANISOU 5857 CB ALA B 368 11949 7651 6825 1966 1014 1829 C +ATOM 5858 N GLY B 369 33.555 -14.856 70.271 1.00 66.59 N +ANISOU 5858 N GLY B 369 11266 7473 6561 2313 619 1920 N +ATOM 5859 CA GLY B 369 34.739 -15.082 69.440 1.00 65.65 C +ANISOU 5859 CA GLY B 369 10989 7308 6647 2438 588 1888 C +ATOM 5860 C GLY B 369 35.214 -13.815 68.753 1.00 62.42 C +ANISOU 5860 C GLY B 369 10418 7111 6185 2393 470 1715 C +ATOM 5861 O GLY B 369 34.701 -12.732 69.013 1.00 59.96 O +ANISOU 5861 O GLY B 369 10118 6982 5680 2282 393 1639 O +ATOM 5862 N TYR B 370 36.199 -13.964 67.870 1.00 61.64 N +ANISOU 5862 N TYR B 370 10171 6973 6275 2482 478 1655 N +ATOM 5863 CA TYR B 370 36.708 -12.860 67.074 1.00 59.35 C +ANISOU 5863 CA TYR B 370 9725 6859 5967 2438 396 1490 C +ATOM 5864 C TYR B 370 36.802 -13.225 65.581 1.00 58.89 C +ANISOU 5864 C TYR B 370 9598 6685 6093 2402 569 1295 C +ATOM 5865 O TYR B 370 36.845 -14.395 65.207 1.00 60.42 O +ANISOU 5865 O TYR B 370 9834 6652 6469 2456 735 1304 O +ATOM 5866 CB TYR B 370 38.061 -12.387 67.623 1.00 60.08 C +ANISOU 5866 CB TYR B 370 9677 7088 6062 2575 186 1624 C +ATOM 5867 CG TYR B 370 39.182 -13.399 67.498 1.00 62.55 C +ANISOU 5867 CG TYR B 370 9889 7244 6631 2770 214 1759 C +ATOM 5868 CD1 TYR B 370 39.450 -14.315 68.517 1.00 64.94 C +ANISOU 5868 CD1 TYR B 370 10256 7438 6979 2910 169 2020 C +ATOM 5869 CD2 TYR B 370 39.989 -13.425 66.365 1.00 62.44 C +ANISOU 5869 CD2 TYR B 370 9712 7190 6821 2820 294 1636 C +ATOM 5870 CE1 TYR B 370 40.487 -15.231 68.396 1.00 67.48 C +ANISOU 5870 CE1 TYR B 370 10464 7603 7572 3107 199 2162 C +ATOM 5871 CE2 TYR B 370 41.022 -14.335 66.235 1.00 64.97 C +ANISOU 5871 CE2 TYR B 370 9922 7352 7409 3011 346 1755 C +ATOM 5872 CZ TYR B 370 41.273 -15.232 67.243 1.00 67.39 C +ANISOU 5872 CZ TYR B 370 10276 7543 7786 3161 296 2021 C +ATOM 5873 OH TYR B 370 42.303 -16.122 67.074 1.00 69.73 O +ANISOU 5873 OH TYR B 370 10442 7667 8384 3365 357 2150 O +ATOM 5874 N TRP B 371 36.816 -12.196 64.741 1.00 57.12 N +ANISOU 5874 N TRP B 371 9280 6613 5809 2299 536 1117 N +ATOM 5875 CA TRP B 371 36.923 -12.334 63.286 1.00 56.56 C +ANISOU 5875 CA TRP B 371 9152 6481 5855 2235 681 919 C +ATOM 5876 C TRP B 371 38.079 -11.480 62.785 1.00 56.02 C +ANISOU 5876 C TRP B 371 8904 6557 5821 2286 588 870 C +ATOM 5877 O TRP B 371 38.216 -10.344 63.185 1.00 54.46 O +ANISOU 5877 O TRP B 371 8647 6558 5487 2256 421 885 O +ATOM 5878 CB TRP B 371 35.615 -11.878 62.609 1.00 54.53 C +ANISOU 5878 CB TRP B 371 8967 6278 5472 2020 744 747 C +ATOM 5879 CG TRP B 371 35.589 -12.075 61.112 1.00 54.38 C +ANISOU 5879 CG TRP B 371 8925 6206 5529 1918 887 544 C +ATOM 5880 CD1 TRP B 371 35.039 -13.122 60.443 1.00 55.30 C +ANISOU 5880 CD1 TRP B 371 9143 6136 5733 1839 1076 446 C +ATOM 5881 CD2 TRP B 371 36.129 -11.197 60.109 1.00 53.17 C +ANISOU 5881 CD2 TRP B 371 8658 6191 5352 1866 859 412 C +ATOM 5882 NE1 TRP B 371 35.217 -12.974 59.096 1.00 55.06 N +ANISOU 5882 NE1 TRP B 371 9077 6124 5717 1737 1163 256 N +ATOM 5883 CE2 TRP B 371 35.876 -11.793 58.862 1.00 54.03 C +ANISOU 5883 CE2 TRP B 371 8815 6194 5517 1755 1034 239 C +ATOM 5884 CE3 TRP B 371 36.805 -9.976 60.150 1.00 51.85 C +ANISOU 5884 CE3 TRP B 371 8363 6220 5118 1891 708 421 C +ATOM 5885 CZ2 TRP B 371 36.276 -11.199 57.651 1.00 53.39 C +ANISOU 5885 CZ2 TRP B 371 8665 6210 5409 1670 1064 86 C +ATOM 5886 CZ3 TRP B 371 37.211 -9.389 58.954 1.00 51.72 C +ANISOU 5886 CZ3 TRP B 371 8264 6285 5099 1816 743 277 C +ATOM 5887 CH2 TRP B 371 36.943 -10.002 57.719 1.00 52.11 C +ANISOU 5887 CH2 TRP B 371 8372 6237 5189 1708 920 116 C +ATOM 5888 N ASN B 372 38.916 -12.042 61.925 1.00 57.44 N +ANISOU 5888 N ASN B 372 9002 6626 6196 2359 713 807 N +ATOM 5889 CA ASN B 372 39.864 -11.252 61.134 1.00 57.84 C +ANISOU 5889 CA ASN B 372 8887 6801 6289 2364 684 711 C +ATOM 5890 C ASN B 372 39.911 -11.790 59.714 1.00 59.48 C +ANISOU 5890 C ASN B 372 9107 6881 6609 2299 915 517 C +ATOM 5891 O ASN B 372 39.285 -12.815 59.411 1.00 60.40 O +ANISOU 5891 O ASN B 372 9355 6806 6784 2259 1087 462 O +ATOM 5892 CB ASN B 372 41.264 -11.202 61.761 1.00 59.14 C +ANISOU 5892 CB ASN B 372 8879 7005 6587 2556 561 874 C +ATOM 5893 CG ASN B 372 41.920 -12.559 61.867 1.00 61.78 C +ANISOU 5893 CG ASN B 372 9188 7105 7179 2740 689 984 C +ATOM 5894 OD1 ASN B 372 42.129 -13.246 60.871 1.00 63.04 O +ANISOU 5894 OD1 ASN B 372 9344 7100 7506 2750 913 860 O +ATOM 5895 ND2 ASN B 372 42.272 -12.942 63.089 1.00 63.19 N +ANISOU 5895 ND2 ASN B 372 9351 7265 7391 2885 551 1225 N +ATOM 5896 N GLU B 373 40.661 -11.102 58.853 1.00 60.59 N +ANISOU 5896 N GLU B 373 9119 7126 6774 2276 928 410 N +ATOM 5897 CA GLU B 373 40.626 -11.366 57.406 1.00 61.35 C +ANISOU 5897 CA GLU B 373 9249 7152 6907 2166 1141 198 C +ATOM 5898 C GLU B 373 41.172 -12.751 57.038 1.00 63.13 C +ANISOU 5898 C GLU B 373 9495 7112 7377 2279 1380 172 C +ATOM 5899 O GLU B 373 40.665 -13.385 56.120 1.00 62.92 O +ANISOU 5899 O GLU B 373 9596 6957 7354 2160 1582 1 O +ATOM 5900 CB GLU B 373 41.356 -10.256 56.639 1.00 61.71 C +ANISOU 5900 CB GLU B 373 9155 7376 6914 2117 1104 109 C +ATOM 5901 CG GLU B 373 40.726 -8.862 56.849 1.00 60.36 C +ANISOU 5901 CG GLU B 373 8981 7439 6513 1986 901 113 C +ATOM 5902 CD GLU B 373 41.439 -7.734 56.102 1.00 60.55 C +ANISOU 5902 CD GLU B 373 8875 7628 6503 1930 869 38 C +ATOM 5903 OE1 GLU B 373 42.615 -7.441 56.408 1.00 62.50 O +ANISOU 5903 OE1 GLU B 373 8954 7920 6871 2054 812 111 O +ATOM 5904 OE2 GLU B 373 40.814 -7.116 55.203 1.00 60.78 O +ANISOU 5904 OE2 GLU B 373 8962 7746 6385 1755 892 -82 O +ATOM 5905 N TYR B 374 42.158 -13.232 57.789 1.00 64.20 N +ANISOU 5905 N TYR B 374 9512 7161 7720 2504 1354 346 N +ATOM 5906 CA TYR B 374 42.826 -14.492 57.462 1.00 67.05 C +ANISOU 5906 CA TYR B 374 9858 7253 8364 2647 1592 341 C +ATOM 5907 C TYR B 374 42.163 -15.707 58.128 1.00 68.52 C +ANISOU 5907 C TYR B 374 10201 7205 8628 2702 1668 442 C +ATOM 5908 O TYR B 374 41.894 -16.716 57.467 1.00 69.65 O +ANISOU 5908 O TYR B 374 10465 7111 8887 2666 1923 315 O +ATOM 5909 CB TYR B 374 44.297 -14.431 57.857 1.00 68.54 C +ANISOU 5909 CB TYR B 374 9803 7453 8783 2876 1536 497 C +ATOM 5910 CG TYR B 374 45.087 -15.676 57.454 1.00 71.96 C +ANISOU 5910 CG TYR B 374 10187 7597 9557 3047 1807 495 C +ATOM 5911 CD1 TYR B 374 45.068 -16.835 58.236 1.00 74.01 C +ANISOU 5911 CD1 TYR B 374 10495 7621 10004 3213 1854 675 C +ATOM 5912 CD2 TYR B 374 45.857 -15.694 56.280 1.00 73.00 C +ANISOU 5912 CD2 TYR B 374 10228 7676 9833 3044 2038 316 C +ATOM 5913 CE1 TYR B 374 45.795 -17.972 57.870 1.00 76.88 C +ANISOU 5913 CE1 TYR B 374 10806 7691 10711 3384 2121 679 C +ATOM 5914 CE2 TYR B 374 46.586 -16.816 55.909 1.00 75.84 C +ANISOU 5914 CE2 TYR B 374 10537 7751 10524 3207 2317 303 C +ATOM 5915 CZ TYR B 374 46.554 -17.953 56.699 1.00 78.10 C +ANISOU 5915 CZ TYR B 374 10864 7793 11017 3382 2360 485 C +ATOM 5916 OH TYR B 374 47.286 -19.065 56.317 1.00 81.37 O +ANISOU 5916 OH TYR B 374 11224 7899 11793 3556 2659 475 O +ATOM 5917 N GLU B 375 41.895 -15.600 59.429 1.00 68.23 N +ANISOU 5917 N GLU B 375 10175 7230 8518 2776 1456 665 N +ATOM 5918 CA GLU B 375 41.319 -16.704 60.183 1.00 69.18 C +ANISOU 5918 CA GLU B 375 10440 7137 8707 2837 1514 799 C +ATOM 5919 C GLU B 375 39.808 -16.763 60.025 1.00 66.38 C +ANISOU 5919 C GLU B 375 10296 6775 8149 2611 1557 676 C +ATOM 5920 O GLU B 375 39.209 -17.782 60.319 1.00 67.02 O +ANISOU 5920 O GLU B 375 10521 6642 8300 2611 1678 719 O +ATOM 5921 CB GLU B 375 41.690 -16.588 61.663 1.00 70.87 C +ANISOU 5921 CB GLU B 375 10589 7429 8908 3001 1271 1102 C +ATOM 5922 CG GLU B 375 43.197 -16.614 61.953 1.00 73.88 C +ANISOU 5922 CG GLU B 375 10735 7819 9516 3235 1194 1270 C +ATOM 5923 CD GLU B 375 43.566 -16.009 63.321 1.00 74.74 C +ANISOU 5923 CD GLU B 375 10760 8131 9506 3325 870 1532 C +ATOM 5924 OE1 GLU B 375 43.362 -16.667 64.368 1.00 77.50 O +ANISOU 5924 OE1 GLU B 375 11193 8390 9861 3420 799 1759 O +ATOM 5925 OE2 GLU B 375 44.078 -14.867 63.360 1.00 73.92 O +ANISOU 5925 OE2 GLU B 375 10514 8278 9294 3291 685 1512 O +ATOM 5926 N ARG B 376 39.190 -15.688 59.542 1.00 63.23 N +ANISOU 5926 N ARG B 376 9905 6600 7516 2419 1465 531 N +ATOM 5927 CA ARG B 376 37.726 -15.583 59.515 1.00 61.74 C +ANISOU 5927 CA ARG B 376 9876 6448 7135 2209 1459 448 C +ATOM 5928 C ARG B 376 37.182 -15.655 60.963 1.00 61.03 C +ANISOU 5928 C ARG B 376 9851 6372 6965 2267 1318 670 C +ATOM 5929 O ARG B 376 37.810 -15.121 61.865 1.00 60.91 O +ANISOU 5929 O ARG B 376 9744 6483 6916 2396 1135 842 O +ATOM 5930 CB ARG B 376 37.092 -16.657 58.606 1.00 63.39 C +ANISOU 5930 CB ARG B 376 10233 6427 7424 2080 1715 270 C +ATOM 5931 CG ARG B 376 37.792 -16.919 57.269 1.00 64.93 C +ANISOU 5931 CG ARG B 376 10398 6539 7732 2051 1913 63 C +ATOM 5932 CD ARG B 376 37.979 -15.701 56.383 1.00 63.08 C +ANISOU 5932 CD ARG B 376 10074 6557 7336 1930 1830 -79 C +ATOM 5933 NE ARG B 376 36.720 -15.113 55.924 1.00 61.24 N +ANISOU 5933 NE ARG B 376 9929 6474 6865 1679 1759 -196 N +ATOM 5934 CZ ARG B 376 36.600 -13.864 55.456 1.00 59.35 C +ANISOU 5934 CZ ARG B 376 9616 6487 6445 1570 1619 -253 C +ATOM 5935 NH1 ARG B 376 37.661 -13.046 55.376 1.00 58.39 N +ANISOU 5935 NH1 ARG B 376 9343 6498 6342 1674 1542 -220 N +ATOM 5936 NH2 ARG B 376 35.399 -13.416 55.079 1.00 58.02 N +ANISOU 5936 NH2 ARG B 376 9517 6436 6091 1355 1552 -332 N +ATOM 5937 N PHE B 377 36.037 -16.291 61.203 1.00 60.74 N +ANISOU 5937 N PHE B 377 9973 6217 6889 2160 1402 666 N +ATOM 5938 CA PHE B 377 35.484 -16.370 62.562 1.00 60.95 C +ANISOU 5938 CA PHE B 377 10077 6254 6825 2201 1297 872 C +ATOM 5939 C PHE B 377 36.074 -17.518 63.395 1.00 63.72 C +ANISOU 5939 C PHE B 377 10469 6382 7359 2402 1352 1091 C +ATOM 5940 O PHE B 377 35.890 -18.678 63.077 1.00 64.71 O +ANISOU 5940 O PHE B 377 10688 6244 7653 2406 1556 1064 O +ATOM 5941 CB PHE B 377 33.969 -16.504 62.503 1.00 59.75 C +ANISOU 5941 CB PHE B 377 10061 6080 6559 1993 1366 787 C +ATOM 5942 CG PHE B 377 33.317 -16.576 63.841 1.00 59.59 C +ANISOU 5942 CG PHE B 377 10133 6068 6439 2012 1296 979 C +ATOM 5943 CD1 PHE B 377 33.495 -15.553 64.771 1.00 58.35 C +ANISOU 5943 CD1 PHE B 377 9927 6130 6112 2064 1094 1100 C +ATOM 5944 CD2 PHE B 377 32.505 -17.646 64.169 1.00 60.83 C +ANISOU 5944 CD2 PHE B 377 10436 6013 6661 1962 1446 1028 C +ATOM 5945 CE1 PHE B 377 32.883 -15.610 66.003 1.00 58.57 C +ANISOU 5945 CE1 PHE B 377 10062 6170 6022 2067 1050 1265 C +ATOM 5946 CE2 PHE B 377 31.898 -17.708 65.413 1.00 61.37 C +ANISOU 5946 CE2 PHE B 377 10599 6091 6625 1972 1401 1209 C +ATOM 5947 CZ PHE B 377 32.085 -16.688 66.328 1.00 60.02 C +ANISOU 5947 CZ PHE B 377 10389 6146 6268 2024 1206 1326 C +ATOM 5948 N VAL B 378 36.785 -17.158 64.457 1.00 64.91 N +ANISOU 5948 N VAL B 378 10549 6641 7469 2560 1163 1313 N +ATOM 5949 CA VAL B 378 37.314 -18.106 65.426 1.00 68.46 C +ANISOU 5949 CA VAL B 378 11032 6924 8056 2755 1158 1578 C +ATOM 5950 C VAL B 378 36.444 -18.105 66.694 1.00 68.99 C +ANISOU 5950 C VAL B 378 11248 7034 7928 2711 1069 1752 C +ATOM 5951 O VAL B 378 36.428 -17.120 67.418 1.00 66.82 O +ANISOU 5951 O VAL B 378 10951 7001 7436 2687 868 1818 O +ATOM 5952 CB VAL B 378 38.758 -17.725 65.801 1.00 69.75 C +ANISOU 5952 CB VAL B 378 11004 7198 8297 2956 979 1734 C +ATOM 5953 CG1 VAL B 378 39.385 -18.777 66.708 1.00 72.60 C +ANISOU 5953 CG1 VAL B 378 11375 7375 8834 3175 967 2033 C +ATOM 5954 CG2 VAL B 378 39.589 -17.538 64.543 1.00 69.55 C +ANISOU 5954 CG2 VAL B 378 10819 7165 8441 2981 1073 1546 C +ATOM 5955 N PRO B 379 35.724 -19.212 66.965 1.00 72.15 N +ANISOU 5955 N PRO B 379 11812 7195 8407 2689 1237 1820 N +ATOM 5956 CA PRO B 379 34.743 -19.211 68.068 1.00 73.83 C +ANISOU 5956 CA PRO B 379 12182 7444 8425 2612 1198 1956 C +ATOM 5957 C PRO B 379 35.160 -19.430 69.532 1.00 77.52 C +ANISOU 5957 C PRO B 379 12708 7933 8810 2760 1050 2285 C +ATOM 5958 O PRO B 379 34.278 -19.346 70.388 1.00 79.89 O +ANISOU 5958 O PRO B 379 13154 8279 8920 2668 1040 2369 O +ATOM 5959 CB PRO B 379 33.762 -20.315 67.659 1.00 74.13 C +ANISOU 5959 CB PRO B 379 12367 7208 8589 2501 1457 1877 C +ATOM 5960 CG PRO B 379 34.536 -21.222 66.790 1.00 75.29 C +ANISOU 5960 CG PRO B 379 12464 7111 9029 2607 1616 1818 C +ATOM 5961 CD PRO B 379 35.585 -20.404 66.114 1.00 73.75 C +ANISOU 5961 CD PRO B 379 12074 7088 8858 2680 1503 1714 C +ATOM 5962 N PHE B 380 36.427 -19.663 69.878 1.00 80.91 N +ANISOU 5962 N PHE B 380 13030 8350 9359 2972 929 2480 N +ATOM 5963 CA PHE B 380 36.819 -20.024 71.303 1.00 84.74 C +ANISOU 5963 CA PHE B 380 13586 8845 9766 3112 776 2834 C +ATOM 5964 C PHE B 380 36.361 -21.417 71.762 1.00 86.71 C +ANISOU 5964 C PHE B 380 14009 8784 10150 3165 956 3024 C +ATOM 5965 O PHE B 380 35.311 -21.523 72.395 1.00 85.86 O +ANISOU 5965 O PHE B 380 14086 8668 9868 3038 1014 3065 O +ATOM 5966 CB PHE B 380 36.333 -19.021 72.392 1.00 83.83 C +ANISOU 5966 CB PHE B 380 13562 9010 9277 3002 582 2901 C +ATOM 5967 CG PHE B 380 36.858 -17.611 72.247 1.00 82.08 C +ANISOU 5967 CG PHE B 380 13190 9097 8896 2959 372 2772 C +ATOM 5968 CD1 PHE B 380 38.119 -17.338 71.704 1.00 82.77 C +ANISOU 5968 CD1 PHE B 380 13056 9246 9144 3087 258 2758 C +ATOM 5969 CD2 PHE B 380 36.104 -16.547 72.719 1.00 80.08 C +ANISOU 5969 CD2 PHE B 380 13018 9065 8342 2792 296 2677 C +ATOM 5970 CE1 PHE B 380 38.583 -16.032 71.597 1.00 80.76 C +ANISOU 5970 CE1 PHE B 380 12670 9267 8746 3032 72 2643 C +ATOM 5971 CE2 PHE B 380 36.571 -15.237 72.621 1.00 78.19 C +ANISOU 5971 CE2 PHE B 380 12655 9089 7964 2746 115 2558 C +ATOM 5972 CZ PHE B 380 37.804 -14.979 72.049 1.00 78.30 C +ANISOU 5972 CZ PHE B 380 12454 9161 8133 2859 0 2540 C +TER 5973 PHE B 380 +HETATM 5974 C1 NAG A 401 4.468 44.853 19.235 1.00 99.17 C +HETATM 5975 C2 NAG A 401 3.494 43.810 18.713 1.00101.93 C +HETATM 5976 C3 NAG A 401 2.160 44.071 19.407 1.00101.48 C +HETATM 5977 C4 NAG A 401 2.368 43.913 20.912 1.00 97.69 C +HETATM 5978 C5 NAG A 401 3.623 44.630 21.434 1.00 98.33 C +HETATM 5979 C6 NAG A 401 4.013 44.143 22.831 1.00100.90 C +HETATM 5980 C7 NAG A 401 3.446 44.662 16.332 1.00101.24 C +HETATM 5981 C8 NAG A 401 3.320 46.107 16.728 1.00 99.17 C +HETATM 5982 N2 NAG A 401 3.476 43.689 17.253 1.00101.71 N +HETATM 5983 O3 NAG A 401 1.170 43.135 18.973 1.00103.66 O +HETATM 5984 O4 NAG A 401 1.205 44.405 21.587 1.00 96.69 O +HETATM 5985 O5 NAG A 401 4.745 44.440 20.567 1.00 95.47 O +HETATM 5986 O6 NAG A 401 5.440 44.108 22.979 1.00101.16 O +HETATM 5987 O7 NAG A 401 3.537 44.363 15.152 1.00 99.30 O +HETATM 5988 C1 NAG A 402 -5.305 28.524 32.646 1.00101.51 C +HETATM 5989 C2 NAG A 402 -5.301 29.895 33.304 1.00104.23 C +HETATM 5990 C3 NAG A 402 -6.019 30.849 32.349 1.00103.14 C +HETATM 5991 C4 NAG A 402 -5.321 30.826 30.983 1.00104.62 C +HETATM 5992 C5 NAG A 402 -5.068 29.408 30.463 1.00103.56 C +HETATM 5993 C6 NAG A 402 -4.154 29.428 29.238 1.00103.05 C +HETATM 5994 C7 NAG A 402 -5.239 29.879 35.808 1.00106.61 C +HETATM 5995 C8 NAG A 402 -3.808 30.335 35.833 1.00102.26 C +HETATM 5996 N2 NAG A 402 -5.891 29.753 34.634 1.00107.95 N +HETATM 5997 O3 NAG A 402 -6.011 32.185 32.861 1.00 99.63 O +HETATM 5998 O4 NAG A 402 -6.113 31.529 30.021 1.00107.80 O +HETATM 5999 O5 NAG A 402 -4.482 28.597 31.484 1.00 99.85 O +HETATM 6000 O6 NAG A 402 -3.764 28.096 28.873 1.00 99.29 O +HETATM 6001 O7 NAG A 402 -5.791 29.611 36.865 1.00111.58 O +HETATM 6002 C1 NAG A 403 -4.776 -3.150 23.917 1.00 87.51 C +HETATM 6003 C2 NAG A 403 -4.866 -3.350 25.417 1.00 85.90 C +HETATM 6004 C3 NAG A 403 -6.308 -3.690 25.789 1.00 89.48 C +HETATM 6005 C4 NAG A 403 -7.345 -2.779 25.113 1.00 92.77 C +HETATM 6006 C5 NAG A 403 -7.003 -2.368 23.672 1.00 90.01 C +HETATM 6007 C6 NAG A 403 -7.775 -1.130 23.221 1.00 87.25 C +HETATM 6008 C7 NAG A 403 -3.438 -4.524 27.035 1.00 76.12 C +HETATM 6009 C8 NAG A 403 -2.438 -5.628 27.244 1.00 73.42 C +HETATM 6010 N2 NAG A 403 -3.926 -4.394 25.799 1.00 81.22 N +HETATM 6011 O3 NAG A 403 -6.471 -3.582 27.207 1.00 91.59 O +HETATM 6012 O4 NAG A 403 -8.600 -3.477 25.117 1.00 95.09 O +HETATM 6013 O5 NAG A 403 -5.616 -2.065 23.537 1.00 90.09 O +HETATM 6014 O6 NAG A 403 -9.171 -1.418 23.127 1.00 86.13 O +HETATM 6015 O7 NAG A 403 -3.776 -3.791 27.948 1.00 75.76 O +HETATM 6016 C1 NAG B 401 49.267 -8.075 60.531 1.00 67.22 C +HETATM 6017 C2 NAG B 401 50.696 -7.651 60.210 1.00 73.68 C +HETATM 6018 C3 NAG B 401 51.592 -8.109 61.357 1.00 78.85 C +HETATM 6019 C4 NAG B 401 51.006 -7.674 62.701 1.00 80.40 C +HETATM 6020 C5 NAG B 401 49.469 -7.741 62.770 1.00 78.31 C +HETATM 6021 C6 NAG B 401 49.016 -6.948 63.991 1.00 79.10 C +HETATM 6022 C7 NAG B 401 51.080 -7.498 57.784 1.00 78.53 C +HETATM 6023 C8 NAG B 401 51.459 -8.266 56.551 1.00 78.18 C +HETATM 6024 N2 NAG B 401 51.105 -8.198 58.926 1.00 75.91 N +HETATM 6025 O3 NAG B 401 52.906 -7.550 61.228 1.00 79.16 O +HETATM 6026 O4 NAG B 401 51.571 -8.515 63.720 1.00 85.28 O +HETATM 6027 O5 NAG B 401 48.828 -7.291 61.545 1.00 71.93 O +HETATM 6028 O6 NAG B 401 47.621 -7.159 64.228 1.00 81.45 O +HETATM 6029 O7 NAG B 401 50.763 -6.319 57.714 1.00 77.90 O +HETATM 6030 C1 NAG B 402 20.050 -19.715 68.582 1.00 99.82 C +HETATM 6031 C2 NAG B 402 19.213 -20.365 67.483 1.00101.95 C +HETATM 6032 C3 NAG B 402 18.915 -21.831 67.793 1.00106.71 C +HETATM 6033 C4 NAG B 402 20.196 -22.569 68.153 1.00107.62 C +HETATM 6034 C5 NAG B 402 20.876 -21.846 69.315 1.00106.20 C +HETATM 6035 C6 NAG B 402 22.152 -22.549 69.765 1.00103.44 C +HETATM 6036 C7 NAG B 402 17.413 -19.305 66.154 1.00 93.56 C +HETATM 6037 C8 NAG B 402 18.155 -19.603 64.882 1.00 91.86 C +HETATM 6038 N2 NAG B 402 17.957 -19.650 67.325 1.00 96.09 N +HETATM 6039 O3 NAG B 402 18.295 -22.473 66.671 1.00107.72 O +HETATM 6040 O4 NAG B 402 19.889 -23.930 68.481 1.00108.32 O +HETATM 6041 O5 NAG B 402 21.191 -20.507 68.916 1.00103.94 O +HETATM 6042 O6 NAG B 402 22.631 -21.927 70.962 1.00102.53 O +HETATM 6043 O7 NAG B 402 16.321 -18.765 66.118 1.00 92.44 O +HETATM 6044 O HOH A 501 5.937 -2.417 10.126 1.00 50.27 O +HETATM 6045 O HOH A 502 13.299 21.368 34.511 1.00 30.14 O +HETATM 6046 O HOH A 503 19.948 35.294 39.105 1.00 43.61 O +HETATM 6047 O HOH A 504 18.097 12.402 33.255 1.00 45.69 O +HETATM 6048 O HOH A 505 2.051 14.988 34.690 1.00 32.93 O +HETATM 6049 O HOH A 506 6.356 8.738 25.883 1.00 29.56 O +HETATM 6050 O HOH A 507 4.260 -10.955 19.644 1.00 53.53 O +HETATM 6051 O HOH A 508 22.860 20.106 11.637 1.00 61.91 O +HETATM 6052 O HOH A 509 12.157 14.397 21.876 1.00 33.80 O +HETATM 6053 O HOH A 510 14.106 33.971 22.150 1.00 36.47 O +HETATM 6054 O HOH A 511 8.632 21.681 36.062 1.00 30.83 O +HETATM 6055 O HOH A 512 9.266 15.219 33.677 1.00 35.63 O +HETATM 6056 O HOH A 513 4.278 36.929 32.014 1.00 34.36 O +HETATM 6057 O HOH A 514 4.650 45.234 34.121 1.00 20.06 O +HETATM 6058 O HOH A 515 3.194 25.628 32.462 1.00 29.18 O +HETATM 6059 O HOH A 516 2.471 28.103 21.806 1.00 36.28 O +HETATM 6060 O HOH A 517 10.928 46.325 29.703 1.00 24.87 O +HETATM 6061 O HOH A 518 15.716 10.556 27.828 1.00 33.77 O +HETATM 6062 O HOH A 519 6.645 11.426 43.988 1.00 34.09 O +HETATM 6063 O HOH A 520 7.681 16.082 24.079 1.00 36.68 O +HETATM 6064 O HOH A 521 18.025 35.184 41.159 1.00 20.37 O +HETATM 6065 O HOH A 522 22.372 22.470 11.413 1.00 44.10 O +HETATM 6066 O HOH A 523 7.149 -9.037 10.249 1.00 52.93 O +HETATM 6067 O HOH A 524 12.745 27.131 42.721 1.00 27.10 O +HETATM 6068 O HOH A 525 11.367 13.864 33.006 1.00 26.62 O +HETATM 6069 O HOH A 526 25.939 19.117 35.120 1.00 47.49 O +HETATM 6070 O HOH A 527 -3.581 -5.209 34.716 1.00 24.85 O +HETATM 6071 O HOH A 528 22.628 36.776 19.783 1.00 31.47 O +HETATM 6072 O HOH A 529 12.762 13.412 40.518 1.00 46.17 O +HETATM 6073 O HOH A 530 14.772 12.932 42.770 1.00 54.09 O +HETATM 6074 O HOH A 531 8.864 -0.076 43.421 1.00 45.86 O +HETATM 6075 O HOH B 501 43.807 -1.992 60.720 1.00 48.20 O +HETATM 6076 O HOH B 502 36.220 5.317 58.079 1.00 40.98 O +HETATM 6077 O HOH B 503 47.275 14.842 51.078 1.00 40.83 O +HETATM 6078 O HOH B 504 38.462 -5.973 54.990 1.00 44.79 O +HETATM 6079 O HOH B 505 26.296 -5.164 66.664 1.00 40.96 O +HETATM 6080 O HOH B 506 38.980 4.280 49.168 1.00 54.10 O +HETATM 6081 O HOH B 507 24.415 3.811 63.559 1.00 42.39 O +HETATM 6082 O HOH B 508 30.439 21.222 45.842 1.00 47.50 O +HETATM 6083 O HOH B 509 52.821 22.258 46.063 1.00 41.28 O +HETATM 6084 O HOH B 510 38.130 0.758 56.338 1.00 40.49 O +HETATM 6085 O HOH B 511 42.263 6.870 50.033 1.00 37.48 O +HETATM 6086 O HOH B 512 38.252 -2.834 56.055 1.00 40.43 O +HETATM 6087 O HOH B 513 33.512 -17.810 56.051 1.00 32.89 O +HETATM 6088 O HOH B 514 53.034 16.474 51.255 1.00 51.89 O +CONECT 493 2454 +CONECT 2454 493 +CONECT 3470 5437 +CONECT 5437 3470 +CONECT 5745 6016 +CONECT 5974 5975 5985 +CONECT 5975 5974 5976 5982 +CONECT 5976 5975 5977 5983 +CONECT 5977 5976 5978 5984 +CONECT 5978 5977 5979 5985 +CONECT 5979 5978 5986 +CONECT 5980 5981 5982 5987 +CONECT 5981 5980 +CONECT 5982 5975 5980 +CONECT 5983 5976 +CONECT 5984 5977 +CONECT 5985 5974 5978 +CONECT 5986 5979 +CONECT 5987 5980 +CONECT 5988 5989 5999 +CONECT 5989 5988 5990 5996 +CONECT 5990 5989 5991 5997 +CONECT 5991 5990 5992 5998 +CONECT 5992 5991 5993 5999 +CONECT 5993 5992 6000 +CONECT 5994 5995 5996 6001 +CONECT 5995 5994 +CONECT 5996 5989 5994 +CONECT 5997 5990 +CONECT 5998 5991 +CONECT 5999 5988 5992 +CONECT 6000 5993 +CONECT 6001 5994 +CONECT 6002 6003 6013 +CONECT 6003 6002 6004 6010 +CONECT 6004 6003 6005 6011 +CONECT 6005 6004 6006 6012 +CONECT 6006 6005 6007 6013 +CONECT 6007 6006 6014 +CONECT 6008 6009 6010 6015 +CONECT 6009 6008 +CONECT 6010 6003 6008 +CONECT 6011 6004 +CONECT 6012 6005 +CONECT 6013 6002 6006 +CONECT 6014 6007 +CONECT 6015 6008 +CONECT 6016 5745 6017 6027 +CONECT 6017 6016 6018 6024 +CONECT 6018 6017 6019 6025 +CONECT 6019 6018 6020 6026 +CONECT 6020 6019 6021 6027 +CONECT 6021 6020 6028 +CONECT 6022 6023 6024 6029 +CONECT 6023 6022 +CONECT 6024 6017 6022 +CONECT 6025 6018 +CONECT 6026 6019 +CONECT 6027 6016 6020 +CONECT 6028 6021 +CONECT 6029 6022 +CONECT 6030 6031 6041 +CONECT 6031 6030 6032 6038 +CONECT 6032 6031 6033 6039 +CONECT 6033 6032 6034 6040 +CONECT 6034 6033 6035 6041 +CONECT 6035 6034 6042 +CONECT 6036 6037 6038 6043 +CONECT 6037 6036 +CONECT 6038 6031 6036 +CONECT 6039 6032 +CONECT 6040 6033 +CONECT 6041 6030 6034 +CONECT 6042 6035 +CONECT 6043 6036 +MASTER 396 0 5 24 32 0 0 6 6073 2 75 60 +END diff --git a/prody/tests/datafiles/pdb6flr_B234.pdb b/prody/tests/datafiles/pdb6flr_B234.pdb new file mode 100644 index 000000000..e212404d2 --- /dev/null +++ b/prody/tests/datafiles/pdb6flr_B234.pdb @@ -0,0 +1,10 @@ +REMARK Selection 'resname HIS and...234 and name CA' +MODEL 1 +ATOM 1 CA AHIS B 234 14.092 -10.803 78.631 0.50 76.86 C +ANISOU 1 CA AHIS B 234 13327 8826 7048 444 3365 1618 C +ENDMDL +MODEL 2 +ATOM 1 CA HIS B 234 13.993 -10.729 78.621 0.50 76.86 C +ANISOU 1 CA HIS B 234 13306 8825 7058 438 3380 1608 C +ENDMDL +END diff --git a/prody/tests/measure/test_contacts.py b/prody/tests/measure/test_contacts.py index 16020cac8..39f949203 100644 --- a/prody/tests/measure/test_contacts.py +++ b/prody/tests/measure/test_contacts.py @@ -21,6 +21,8 @@ UBI_CONTACTS = Contacts(UBI_XYZ) UBI_CONTACTS_PBC = Contacts(UBI_XYZ, UBI_UC) +UBI_ADDH = parseDatafile('1ubi_addH') + class TestContacts(unittest.TestCase): @@ -92,6 +94,13 @@ def testAtomicArgumentSwitching(self): neighbors2.sort() self.assertEqual(neighbors1, neighbors2) + def testSeqsep(self): + + neighbors = findNeighbors(UCA, UCA_RADIUS, seqsep=3) + n_neighbors = (buildDistMatrix(UCA, seqsep=3, + format='arr') <= UCA_RADIUS).sum() + assert_equal(len(neighbors), n_neighbors) + def testPBCCoordArgumentSwitching(self): dist = 12. diff --git a/prody/tests/proteins/test_pdbfile.py b/prody/tests/proteins/test_pdbfile.py index 3f34f453a..be9f1a4e2 100644 --- a/prody/tests/proteins/test_pdbfile.py +++ b/prody/tests/proteins/test_pdbfile.py @@ -30,6 +30,8 @@ def setUp(self): self.hex = DATA_FILES['hex'] self.h36 = DATA_FILES['h36'] + self.altlocs = DATA_FILES['6flr'] + def testUsualCase(self): """Test the outcome of a simple parsing scenario.""" @@ -186,6 +188,57 @@ def testHybrid36Serial(self): serial = '100000' self.assertEqual(str(parsePDB(path).getSerials()[100000-1]), serial, 'parsePDB failed to parse Hybrid36 serial number') + + def testAltlocAllToMultiAtoms(self): + """Test number of coordinate sets and atoms with altloc='all'.""" + + path = pathDatafile(self.altlocs['file']) + + ag = parsePDB(path, altloc="all") + self.assertEqual(ag.numAtoms(), self.altlocs['atoms_altloc'], + 'parsePDB failed to parse correct number of atoms with altloc "all"') + self.assertEqual(ag.numCoordsets(), 1, + 'parsePDB failed to parse correct number of coordsets (1) with altloc "all"') + + hisB234 = ag.select('resname HIS and chain B and resnum 234 and name CA') + self.assertEqual(hisB234.numAtoms(), self.altlocs['num_altlocs'], + 'parsePDB failed to parse correct number of His B234 CA atoms (2) with altloc "all"') + + self.assertEqual(hisB234.getAnisous().shape, (self.altlocs['num_altlocs'], 6), + 'parsePDB failed to have right shape for His B234 CA atoms getAnisous (2, 6) with altloc "all"') + + assert_allclose(hisB234.getAnisous()[0], self.altlocs['anisousA'][0], + err_msg='parsePDB failed to have right His B234 CA atoms getAnisous A with altloc "all"') + + assert_allclose(hisB234.getAnisous()[1], self.altlocs['anisousB'][0], + err_msg='parsePDB failed to have right His B234 CA atoms getAnisous B with altloc "all"') + + def testAltlocNoneToMultiCoordets(self): + """Test number of coordinate sets and atoms with altloc=None.""" + + path = pathDatafile(self.altlocs['file']) + + ag = parsePDB(path, altloc=None) + self.assertEqual(ag.numAtoms(), self.altlocs['atoms_single'], + 'parsePDB failed to parse correct number of atoms with altloc None') + self.assertEqual(ag.numCoordsets(), self.altlocs['num_altlocs'], + 'parsePDB failed to parse correct number of coordsets (2) with altloc None') + + hisB234 = ag.select('resname HIS and chain B and resnum 234 and name CA') + self.assertEqual(hisB234.numAtoms(), 1, + 'parsePDB failed to parse correct number of His B234 CA atoms (1) with altloc None') + + self.assertEqual(hisB234.getAnisous().shape, (1, 6), + 'parsePDB failed to have right shape for His B234 CA atoms getAnisous (1, 6) with altloc None') + + assert_allclose(hisB234.getAnisous(), self.altlocs['anisousA'], + err_msg='parsePDB failed to have right His B234 CA atoms getAnisous A with altloc None') + + hisB234.setACSIndex(1) + + assert_allclose(hisB234.getAnisous(), self.altlocs['anisousB'], + err_msg='parsePDB failed to have right His B234 CA atoms getAnisous B with altloc None') + ''' def testBiomolArgument(self): @@ -209,6 +262,11 @@ def setUp(self): self.ag = parsePDB(self.pdb['path']) self.tmp = os.path.join(TEMPDIR, 'test.pdb') + self.ens = PDBEnsemble() + self.ens.setAtoms(self.ag) + self.ens.setCoords(self.ag.getCoords()) + self.ens.addCoordset(self.ag.getCoordsets()) + self.ubi = parsePDB(DATA_FILES['1ubi']['path'], secondary=True) self.hex = parsePDB(DATA_FILES['hex']['path']) @@ -217,6 +275,10 @@ def setUp(self): self.hex_ter = parsePDB(DATA_FILES['hex_ter']['path']) self.h36_ter = parsePDB(DATA_FILES['h36_ter']['path']) + self.altlocs = DATA_FILES['6flr'] + self.altloc_full = parsePDB(self.altlocs['path'], altloc=None) + self.altloc_sel = DATA_FILES['6flr_sel']['path'] + msg = 'user does not have write access to temp dir {0:s}'.format(TEMPDIR) @dec.slow @@ -368,7 +430,37 @@ def testWritingHybrid36Ter(self): serial_A0000_line = lines[100000] self.assertEqual(serial_A0000_line[6:11], 'A0000', - 'writePDB failed to write correct h36 serial') + 'writePDB failed to write correct h36 serial') + + def testWritingAltlocModels(self): + """Test if output from writing hexadecimal with TER lines is as expected.""" + + hisB234 = self.altloc_full.select('resname HIS and chain B and resnum 234 and name CA') + out = writePDB(self.tmp, hisB234) + + fi = open(out, 'r') + lines1 = fi.readlines() + fi.close() + + fi = open(self.altloc_sel, 'r') + lines2 = fi.readlines() + fi.close() + + self.assertEqual(lines1[4], lines2[4], + 'writePDB failed to write correct ANISOU line 4 for 6flr selection with altloc None') + + self.assertEqual(lines1[8], lines2[8], + 'writePDB failed to write correct ANISOU line 8 for 6flr selection with altloc None') + + def testWriteEnsembleToPDB(self): + """Test that writePDB can handle ensembles.""" + + out = writePDB(self.tmp, self.ens) + out = parsePDB(out) + self.assertEqual(out.numCoordsets(), self.ens.numCoordsets(), + 'failed to write correct number of models from ensemble') + assert_equal(out.getCoords(), self.ag.getCoordsets(0), + 'failed to write ensemble model 1 coordinates correctly') @dec.slow def tearDown(self): diff --git a/prody/utilities/checkers.py b/prody/utilities/checkers.py index 647747d12..16cea72c3 100644 --- a/prody/utilities/checkers.py +++ b/prody/utilities/checkers.py @@ -2,7 +2,7 @@ from numpy import any, float32, tile -__all__ = ['checkCoords', 'checkWeights', 'checkTypes'] +__all__ = ['checkCoords', 'checkWeights', 'checkTypes', 'checkAnisous'] COORDS_NDIM = set([2]) CSETS_NDIMS = set([2, 3]) @@ -135,3 +135,57 @@ def incr(n, i): .format(repr(arg), tstr, repr(type(val).__name__))) return True + +A_CSETS_NDIMS = set([2, 6]) + +def checkAnisous(anisous, csets=False, natoms=None, dtype=(float, float32), + name='anisous'): + """Returns **True** if shape, dimensionality, and data type of *anisous* + array are as expected. + + :arg anisous: anisous array + + :arg csets: whether multiple coordinate sets (i.e. ``.ndim in (2, 3)``) are + allowed, default is **False** + + :arg natoms: number of atoms, if **None** number of atoms is not checked + + :arg dtype: allowed data type(s), default is ``(float, numpy.float32)``, + if **None** data type is not checked + + :arg name: name of the coordinate argument + + :raises: :exc:`TypeError` when *anisous* is not an instance of + :class:`numpy.ndarray` + + :raises: :exc:`ValueError` when wrong shape, dimensionality, or data type + is encountered""" + + try: + ndim, shape = anisous.ndim, anisous.shape + except AttributeError: + raise TypeError('anisous must be a numpy.ndarray instance') + + ndims = A_CSETS_NDIMS if csets else COORDS_NDIM + if ndim not in ndims: + raise ValueError(str(name) + '.ndim must be ' + + ' or '.join([str(d) for d in ndims])) + + elif shape[-1] != 6: + raise ValueError(str(name) + '.shape[-1] must be 6') + + elif natoms and shape[-2] != natoms: + raise ValueError(str(name) + '.shape[-2] must match number of atoms') + + elif dtype: + if isinstance(dtype, type) and anisous.dtype != dtype: + raise ValueError(str(name) + '.dtype must be ' + dtype.__name__) + elif anisous.dtype not in dtype: + if len(dtype) > 1: + msg = ', '.join([repr(dt.__name__) for dt in dtype[:-1]] + ) + ', or ' + repr(dtype[-1].__name__) + else: + msg = dtype[0].__name__ + raise ValueError(str(name) + '.dtype must be ' + msg) + + return True