diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000000..1d16e9ff92
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,70 @@
+# Copyright 2024 Google LLC
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+[build-system]
+requires = ["setuptools"]
+build-backend = "setuptools.build_meta"
+
+[project]
+name = "google-cloud-spanner"
+authors = [{ name = "Google LLC", email = "googleapis-packages@google.com" }]
+license = { text = "Apache 2.0" }
+requires-python = ">=3.7"
+description = "Google Cloud Spanner API client library"
+readme = "README.rst"
+classifiers = [
+  "Development Status :: 5 - Production/Stable",
+  "Intended Audience :: Developers",
+  "License :: OSI Approved :: Apache Software License",
+  "Programming Language :: Python",
+  "Programming Language :: Python :: 3",
+  "Programming Language :: Python :: 3.7",
+  "Programming Language :: Python :: 3.8",
+  "Programming Language :: Python :: 3.9",
+  "Programming Language :: Python :: 3.10",
+  "Programming Language :: Python :: 3.11",
+  "Programming Language :: Python :: 3.12",
+  "Operating System :: OS Independent",
+  "Topic :: Internet",
+]
+dependencies = [
+  "google-api-core[grpc] >= 1.34.0, < 3.0.0dev, != 2.0.*, != 2.1.*, != 2.2.*, != 2.3.*, != 2.4.*, !=2.5.*, != 2.6.*, != 2.7.*, != 2.8.*, != 2.9.*, != 2.10.*",
+  "google-cloud-core >= 1.4.4, < 3.0dev",
+  "grpc-google-iam-v1 >= 0.12.4, < 1.0.0dev",
+  "proto-plus >= 1.22.0, < 2.0.0dev",
+  "sqlparse >= 0.4.4",
+  "proto-plus >= 1.22.2, < 2.0.0dev; python_version >= '3.11'",
+  "protobuf >= 3.20.2, < 6.0.0dev, != 4.21.0, != 4.21.1, != 4.21.2, != 4.21.3, != 4.21.4, != 4.21.5",
+  "grpc-interceptor >= 0.15.4",
+]
+dynamic = ["version"]
+
+[project.urls]
+Repository = "https://github.com/googleapis/python-spanner"
+
+[project.optional-dependencies]
+tracing = [
+  "opentelemetry-api >= 1.22.0",
+  "opentelemetry-sdk >= 1.22.0",
+  "opentelemetry-semantic-conventions >= 0.43b0",
+]
+libcst = ["libcst >= 0.2.5"]
+
+[tool.setuptools]
+
+[tool.setuptools.dynamic]
+version = { attr = "google.cloud.spanner_v1.gapic_version.__version__" }
+
+[tool.setuptools.packages.find]
+include = ["google*"]
diff --git a/setup.py b/setup.py
index 544d117fd7..6c4bccf40d 100644
--- a/setup.py
+++ b/setup.py
@@ -13,90 +13,8 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 #
-import io
-import os
 
 import setuptools  # type: ignore
 
-package_root = os.path.abspath(os.path.dirname(__file__))
 
-name = "google-cloud-spanner"
-
-
-description = "Google Cloud Spanner API client library"
-
-version = {}
-with open(os.path.join(package_root, "google/cloud/spanner_v1/gapic_version.py")) as fp:
-    exec(fp.read(), version)
-version = version["__version__"]
-
-if version[0] == "0":
-    release_status = "Development Status :: 4 - Beta"
-else:
-    release_status = "Development Status :: 5 - Production/Stable"
-
-dependencies = [
-    "google-api-core[grpc] >= 1.34.0, <3.0.0dev,!=2.0.*,!=2.1.*,!=2.2.*,!=2.3.*,!=2.4.*,!=2.5.*,!=2.6.*,!=2.7.*,!=2.8.*,!=2.9.*,!=2.10.*",
-    "google-cloud-core >= 1.4.4, < 3.0dev",
-    "grpc-google-iam-v1 >= 0.12.4, <1.0.0dev",
-    "proto-plus >= 1.22.0, <2.0.0dev",
-    "sqlparse >= 0.4.4",
-    "proto-plus >= 1.22.2, <2.0.0dev; python_version>='3.11'",
-    "protobuf>=3.20.2,<6.0.0dev,!=4.21.0,!=4.21.1,!=4.21.2,!=4.21.3,!=4.21.4,!=4.21.5",
-    "grpc-interceptor >= 0.15.4",
-]
-extras = {
-    "tracing": [
-        "opentelemetry-api >= 1.22.0",
-        "opentelemetry-sdk >= 1.22.0",
-        "opentelemetry-semantic-conventions >= 0.43b0",
-    ],
-    "libcst": "libcst >= 0.2.5",
-}
-
-url = "https://github.com/googleapis/python-spanner"
-
-package_root = os.path.abspath(os.path.dirname(__file__))
-
-readme_filename = os.path.join(package_root, "README.rst")
-with io.open(readme_filename, encoding="utf-8") as readme_file:
-    readme = readme_file.read()
-
-packages = [
-    package
-    for package in setuptools.find_namespace_packages()
-    if package.startswith("google")
-]
-
-setuptools.setup(
-    name=name,
-    version=version,
-    description=description,
-    long_description=readme,
-    author="Google LLC",
-    author_email="googleapis-packages@google.com",
-    license="Apache 2.0",
-    url=url,
-    classifiers=[
-        release_status,
-        "Intended Audience :: Developers",
-        "License :: OSI Approved :: Apache Software License",
-        "Programming Language :: Python",
-        "Programming Language :: Python :: 3",
-        "Programming Language :: Python :: 3.7",
-        "Programming Language :: Python :: 3.8",
-        "Programming Language :: Python :: 3.9",
-        "Programming Language :: Python :: 3.10",
-        "Programming Language :: Python :: 3.11",
-        "Programming Language :: Python :: 3.12",
-        "Operating System :: OS Independent",
-        "Topic :: Internet",
-    ],
-    platforms="Posix; MacOS X; Windows",
-    packages=packages,
-    install_requires=dependencies,
-    extras_require=extras,
-    python_requires=">=3.7",
-    include_package_data=True,
-    zip_safe=False,
-)
+setuptools.setup()