diff --git a/pyproject.toml b/pyproject.toml
index c3a1555..5c225ac 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -21,10 +21,10 @@ python = "^3.9"
 biosimulators_utils = {version = "^0.1.151", extras = ["logging", "sbml"]}
 cobra = "<= 0.23.0"
 kisao = "^2.34"
-libroadrunner = "< 2.2.0"
+libroadrunner = "> 2.2.0"
 lxml = "^4.5"
 masspy = "^0.1.7"
-numpy = "< 1.22.0"
+numpy = "> 1.22.0"
 docker = "^7.1.0"
 
 [tool.poetry.group.dev.dependencies]