Error: Unchecked runtime.lastError: Could not establish connection. Receiving end does not exist.

[localhorst]

My setup:
Windows 10
Chrome 92.0.4515.159
Keepass 2.48.1
KeePassHttp 1.8.4.2 (Error was present with 1.8.4.1, too)
KeePassHelper 0.5.0

Connection to KeePass not possible anymore.
I get the popup to "Confirm New Key Association" and name my browser instance every time I click on the extension icon in Chrome.
Keepass freezes after that ("not responding") for a while, but can be used again after ~2 minutes

Error in Chrome Extension Seetings:
Unchecked runtime.lastError: Could not establish connection. Receiving end does not exist.

Extension Settings > Connection > KeePassHTTP host: http://localhost:19455 > Check: Returns "Looks Good"

Regards:
Mateng

Edit: It worked again after a few days and a clean reboot.
Edit 2: It stopped working with the same error after another day.
Edit 3: A Solution (or a workaround) seems to be to go into KeePass 2 > Plugins and delete the Plugin Cache

[belaviyo]

Please try v0.6.1. Note that the popup window needs to be open during the initial key exchange.