diff --git a/tools/run_tests/artifacts/artifact_targets.py b/tools/run_tests/artifacts/artifact_targets.py
index fe0180a282589..a6c1652f97a64 100644
--- a/tools/run_tests/artifacts/artifact_targets.py
+++ b/tools/run_tests/artifacts/artifact_targets.py
@@ -208,6 +208,8 @@ def build_jobspec(self, inner_jobs=None):
                 # As we won't strip the binary with auditwheel (see below), strip
                 # it at link time.
                 environ["LDFLAGS"] = "-s"
+                # We're using musllinux aarch64 image to build this artifact so no crosscompiling required.
+                environ["GRPC_BUILD_GRPCIO_TOOLS_DEPENDENTS"] = "TRUE"
             else:
                 environ["GRPC_RUN_AUDITWHEEL_REPAIR"] = "TRUE"
                 environ["GRPC_PYTHON_BUILD_WITH_STATIC_LIBSTDCXX"] = "TRUE"