diff --git a/pkgs/applications/networking/browsers/ladybird/default.nix b/pkgs/applications/networking/browsers/ladybird/default.nix
index 60157ca262826..450ede63d8e51 100644
--- a/pkgs/applications/networking/browsers/ladybird/default.nix
+++ b/pkgs/applications/networking/browsers/ladybird/default.nix
@@ -74,18 +74,6 @@ stdenv.mkDerivation (finalAttrs: {
     substituteInPlace Meta/CMake/lagom_install_options.cmake \
       --replace-fail "\''${CMAKE_INSTALL_BINDIR}" "bin" \
       --replace-fail "\''${CMAKE_INSTALL_LIBDIR}" "lib"
-
-    # libwebp is not built with cmake support yet
-    # https://github.com/NixOS/nixpkgs/issues/334148
-    cat > Meta/CMake/FindWebP.cmake <<'EOF'
-    find_package(PkgConfig)
-    pkg_check_modules(WEBP libwebp REQUIRED)
-    include_directories(''${WEBP_INCLUDE_DIRS})
-    link_directories(''${WEBP_LIBRARY_DIRS})
-    EOF
-    substituteInPlace Userland/Libraries/LibGfx/CMakeLists.txt \
-      --replace-fail 'WebP::' "" \
-      --replace-fail libwebpmux webpmux
   '';
 
   preConfigure = ''
diff --git a/pkgs/development/libraries/libwebp/default.nix b/pkgs/development/libraries/libwebp/default.nix
index f788a7f59b9c6..abd1e1bd9afe9 100644
--- a/pkgs/development/libraries/libwebp/default.nix
+++ b/pkgs/development/libraries/libwebp/default.nix
@@ -1,27 +1,34 @@
-{ lib, stdenv, fetchFromGitHub, autoreconfHook, libtool
-, threadingSupport ? true # multi-threading
-, openglSupport ? false, libglut, libGL, libGLU # OpenGL (required for vwebp)
-, pngSupport ? true, libpng # PNG image format
-, jpegSupport ? true, libjpeg # JPEG image format
-, tiffSupport ? true, libtiff # TIFF image format
-, gifSupport ? true, giflib # GIF image format
-, alignedSupport ? false # Force aligned memory operations
-, swap16bitcspSupport ? false # Byte swap for 16bit color spaces
-, experimentalSupport ? false # Experimental code
-, libwebpmuxSupport ? true # Build libwebpmux
-, libwebpdemuxSupport ? true # Build libwebpdemux
-, libwebpdecoderSupport ? true # Build libwebpdecoder
+{
+  lib,
+  stdenv,
+  fetchFromGitHub,
+  cmake,
+  threadingSupport ? true, # multi-threading
+  openglSupport ? false,
+  libglut,
+  libGL,
+  libGLU, # OpenGL (required for vwebp)
+  pngSupport ? true,
+  libpng, # PNG image format
+  jpegSupport ? true,
+  libjpeg, # JPEG image format
+  tiffSupport ? true,
+  libtiff, # TIFF image format
+  gifSupport ? true,
+  giflib, # GIF image format
+  swap16bitcspSupport ? false, # Byte swap for 16bit color spaces
+  libwebpmuxSupport ? true, # Build libwebpmux
 
-# for passthru.tests
-, gd
-, graphicsmagick
-, haskellPackages
-, imagemagick
-, imlib2
-, libjxl
-, opencv
-, python3
-, vips
+  # for passthru.tests
+  gd,
+  graphicsmagick,
+  haskellPackages,
+  imagemagick,
+  imlib2,
+  libjxl,
+  opencv,
+  python3,
+  vips,
 }:
 
 stdenv.mkDerivation rec {
@@ -29,39 +36,47 @@ stdenv.mkDerivation rec {
   version = "1.4.0";
 
   src = fetchFromGitHub {
-    owner  = "webmproject";
-    repo   = pname;
-    rev    = "v${version}";
-    hash   = "sha256-OR/VzKNn3mnwjf+G+RkEGAaaKrhVlAu1e2oTRwdsPj8=";
+    owner = "webmproject";
+    repo = "libwebp";
+    rev = "v${version}";
+    hash = "sha256-OR/VzKNn3mnwjf+G+RkEGAaaKrhVlAu1e2oTRwdsPj8=";
   };
 
-  configureFlags = [
-    (lib.enableFeature threadingSupport "threading")
-    (lib.enableFeature openglSupport "gl")
-    (lib.enableFeature pngSupport "png")
-    (lib.enableFeature jpegSupport "jpeg")
-    (lib.enableFeature tiffSupport "tiff")
-    (lib.enableFeature gifSupport "gif")
-    (lib.enableFeature alignedSupport "aligned")
-    (lib.enableFeature swap16bitcspSupport "swap-16bit-csp")
-    (lib.enableFeature experimentalSupport "experimental")
-    (lib.enableFeature libwebpmuxSupport "libwebpmux")
-    (lib.enableFeature libwebpdemuxSupport "libwebpdemux")
-    (lib.enableFeature libwebpdecoderSupport "libwebpdecoder")
+  cmakeFlags = [
+    (lib.cmakeBool "BUILD_SHARED_LIBS" true)
+    (lib.cmakeBool "WEBP_USE_THREAD" threadingSupport)
+    (lib.cmakeBool "WEBP_BUILD_VWEBP" openglSupport)
+    (lib.cmakeBool "WEBP_BUILD_IMG2WEBP" (pngSupport || jpegSupport || tiffSupport))
+    (lib.cmakeBool "WEBP_BUILD_GIF2WEBP" gifSupport)
+    (lib.cmakeBool "WEBP_BUILD_ANIM_UTILS" false) # Not installed
+    (lib.cmakeBool "WEBP_BUILD_EXTRAS" false) # Not installed
+    (lib.cmakeBool "WEBP_ENABLE_SWAP_16BIT_CSP" swap16bitcspSupport)
+    (lib.cmakeBool "WEBP_BUILD_LIBWEBPMUX" libwebpmuxSupport)
   ];
 
-  nativeBuildInputs = [ autoreconfHook libtool ];
-  buildInputs = [ ]
-    ++ lib.optionals openglSupport [ libglut libGL libGLU ]
+  nativeBuildInputs = [ cmake ];
+  buildInputs =
+    [ ]
+    ++ lib.optionals openglSupport [
+      libglut
+      libGL
+      libGLU
+    ]
     ++ lib.optionals pngSupport [ libpng ]
     ++ lib.optionals jpegSupport [ libjpeg ]
     ++ lib.optionals tiffSupport [ libtiff ]
     ++ lib.optionals gifSupport [ giflib ];
 
-  enableParallelBuilding = true;
-
   passthru.tests = {
-    inherit gd graphicsmagick imagemagick imlib2 libjxl opencv vips;
+    inherit
+      gd
+      graphicsmagick
+      imagemagick
+      imlib2
+      libjxl
+      opencv
+      vips
+      ;
     inherit (python3.pkgs) pillow imread;
     haskell-webp = haskellPackages.webp;
   };