diff --git a/.gitignore b/.gitignore index 789df8adf..17cb00b1f 100644 --- a/.gitignore +++ b/.gitignore @@ -13,3 +13,4 @@ notebooks/output/*tsv notebooks/input/go.db +notebooks/api-key.txt diff --git a/notebooks/enrichment_with_OAK.ipynb b/notebooks/enrichment_with_OAK.ipynb index 3831444b6..f8cc006b9 100644 --- a/notebooks/enrichment_with_OAK.ipynb +++ b/notebooks/enrichment_with_OAK.ipynb @@ -2,37 +2,287 @@ "cells": [ { "cell_type": "code", - "execution_count": 14, + "execution_count": 25, "id": "5f6b6b9a", "metadata": {}, "outputs": [], "source": [ "from oaklib.implementations.pronto.pronto_implementation import ProntoImplementation\n", - "from oaklib.resource import OntologyResource" + "from oaklib.resource import OntologyResource\n", + "import pandas as pd\n", + "#from pandasql import sqldf\n", + "import duckdb\n", + "from scipy import stats" ] }, { "cell_type": "code", - "execution_count": 15, - "id": "dbe9e522", + "execution_count": 26, + "id": "075c8914", + "metadata": {}, + "outputs": [], + "source": [ + "yeast_annot = pd.read_csv(\"../4932.tab\",sep=\"\\t\",header=0)" + ] + }, + { + "cell_type": "code", + "execution_count": 27, + "id": "1b37c5e2", + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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locusIdaccessionGIscaffoldIdstartstopstrandsysNamenamedescCOGCOGFunCOGDescTIGRFamTIGRRolesGOECECDesc
06580634NP_009332.16319249.022372321691807-YAL068CPAU8Pau8p (RefSeq)NaNNaNNaNNaNNaNGO:0006950NaNNaN
16580635NP_878038.133438754.022372324802707+YAL067W-AYAL067W-APutative protein of unknown function; identifi...NaNNaNNaNNaNNaNNaNNaNNaN
26580636NP_009333.16319250.022372390177236-YAL067CSEO1Putative permease, member of the allantoate tr...NaNNaNNaNNaNNaNNaNNaNNaN
36580637NP_009335.16319252.02237231195211566-YAL065CYAL065CPutative protein of unknown function; has homo...NaNNaNNaNNaNNaNNaNNaNNaN
46580638NP_009336.16319253.02237231204712427+YAL064W-BYAL064W-BFungal-specific protein of unknown function (R...NaNNaNNaNNaNNaNNaNNaNNaN
\n", + "
" + ], + "text/plain": [ + " locusId accession GI scaffoldId start stop strand \\\n", + "0 6580634 NP_009332.1 6319249.0 223723 2169 1807 - \n", + "1 6580635 NP_878038.1 33438754.0 223723 2480 2707 + \n", + "2 6580636 NP_009333.1 6319250.0 223723 9017 7236 - \n", + "3 6580637 NP_009335.1 6319252.0 223723 11952 11566 - \n", + "4 6580638 NP_009336.1 6319253.0 223723 12047 12427 + \n", + "\n", + " sysName name desc \\\n", + "0 YAL068C PAU8 Pau8p (RefSeq) \n", + "1 YAL067W-A YAL067W-A Putative protein of unknown function; identifi... \n", + "2 YAL067C SEO1 Putative permease, member of the allantoate tr... \n", + "3 YAL065C YAL065C Putative protein of unknown function; has homo... \n", + "4 YAL064W-B YAL064W-B Fungal-specific protein of unknown function (R... \n", + "\n", + " COG COGFun COGDesc TIGRFam TIGRRoles GO EC ECDesc \n", + "0 NaN NaN NaN NaN NaN GO:0006950 NaN NaN \n", + "1 NaN NaN NaN NaN NaN NaN NaN NaN \n", + "2 NaN NaN NaN NaN NaN NaN NaN NaN \n", + "3 NaN NaN NaN NaN NaN NaN NaN NaN \n", + "4 NaN NaN NaN NaN NaN NaN NaN NaN " + ] + }, + "execution_count": 27, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "yeast_annot.head()" + ] + }, + { + "cell_type": "code", + "execution_count": 28, + "id": "7c7fbfc9", "metadata": {}, "outputs": [], "source": [ - "gene_ids = ['NCBIGene:6295',\n", - " 'NCBIGene:1258',\n", - " 'NCBIGene:3614',\n", - " 'NCBIGene:26121',\n", - " 'NCBIGene:7275',\n", - " 'NCBIGene:55857',\n", - " 'NCBIGene:79797',\n", - " 'NCBIGene:10594',\n", - " 'NCBIGene:64218',\n", - " 'NCBIGene:7401']" + "#yeast_annot.query(\"GO like %GO:0006950%\")\n", + "genes_stress_response_data = duckdb.query(\"SELECT * FROM yeast_annot WHERE GO LIKE '%GO:0006950%'\").df()" + ] + }, + { + "cell_type": "code", + "execution_count": 29, + "id": "dbe9e522", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "0 YAL068C\n", + "1 YAR020C\n", + "2 YBL108C-A\n", + "3 YBR067C\n", + "4 YBR301W\n", + "5 YCR104W\n", + "6 YDR542W\n", + "7 YEL049W\n", + "8 YER011W\n", + "9 YFL020C\n", + "10 YFL014W\n", + "11 YGL261C\n", + "12 YGR294W\n", + "13 YHL046C\n", + "14 YIL176C\n", + "15 YIL011W\n", + "16 YIR041W\n", + "17 YJL223C\n", + "18 YJR150C\n", + "19 YJR151C\n", + "20 YKL224C\n", + "21 YLL064C\n", + "22 YLL025W\n", + "23 YLR037C\n", + "24 YLR040C\n", + "25 YLR461W\n", + "26 YMR325W\n", + "27 YNR076W\n", + "28 YOL161C\n", + "29 YOR009W\n", + "30 YOR010C\n", + "31 YOR394W\n", + "32 YPL282C\n", + "Name: sysName, dtype: object" + ] + }, + "execution_count": 29, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "gene_ids = genes_stress_response_data['sysName']\n", + "gene_ids" ] }, { "cell_type": "code", - "execution_count": 20, + "execution_count": 30, "id": "0d07d788", "metadata": {}, "outputs": [], @@ -42,7 +292,7 @@ }, { "cell_type": "code", - "execution_count": 21, + "execution_count": 38, "id": "d6eacf80", "metadata": {}, "outputs": [ @@ -51,14 +301,12 @@ "output_type": "stream", "text": [ " rdfs:subClassOf ! subClassOf\n", - " GO:0043231 ! intracellular membrane-bounded organelle\n", - " BFO:0000050 ! part of\n", - " GO:0005737 ! cytoplasm\n" + " GO:0050896 ! response to stimulus\n" ] } ], "source": [ - "rels = oi.get_outgoing_relationships_by_curie('GO:0005773')\n", + "rels = oi.get_outgoing_relationships_by_curie('GO:0006950')\n", "for rel, parents in rels.items():\n", " print(f' {rel} ! {oi.get_label_by_curie(rel)}')\n", " for parent in parents:\n", @@ -67,22 +315,36 @@ }, { "cell_type": "code", - "execution_count": null, + "execution_count": 39, "id": "27c908fb", "metadata": {}, - "outputs": [], + "outputs": [ + { + "data": { + "text/plain": [ + "['GO:0006950']" + ] + }, + "execution_count": 39, + "metadata": {}, + "output_type": "execute_result" + } + ], "source": [ - "labels = " + "labels = gene_ids\n", + "hypotheses = [\"GO:0006950\"]\n", + "hypotheses" ] }, { "cell_type": "code", - "execution_count": 17, + "execution_count": 33, "id": "d8ee5144", "metadata": {}, "outputs": [], "source": [ - "def enrichment_test(subjects=None, background=None, hypotheses=None, inferred_types=None, ontology_labels=None, threshold=0.05, labels=False, direction='greater'):\n", + "#removed: inferred_types=None,\n", + "def enrichment_test(subjects=None, background=None, hypotheses=None, ontology_labels=None, threshold=0.05, labels=False, direction='greater'):\n", " \"\"\"\n", " Performs term enrichment analysis.\n", "\n", @@ -118,13 +380,13 @@ " sample_count = {}\n", " potential_hypotheses = set()\n", " sample_size = len(subjects)\n", - " for s in subjects:\n", - " potential_hypotheses.update(inferred_types(s))\n", - " if hypotheses is None:\n", - " hypotheses = potential_hypotheses\n", - " else:\n", - " hypotheses = potential_hypotheses.intersection(hypotheses)\n", - " logger.info(\"Hypotheses: {}\".format(hypotheses))\n", + " #for s in subjects:\n", + " # potential_hypotheses.update(inferred_types(s))\n", + " #if hypotheses is None:\n", + " # hypotheses = potential_hypotheses\n", + " #else:\n", + " # hypotheses = potential_hypotheses.intersection(hypotheses)\n", + " print(\"Hypotheses: {}\".format(hypotheses))\n", "\n", " # get background counts\n", " # TODO: consider doing this ahead of time\n", @@ -141,17 +403,23 @@ " for c in hypotheses:\n", " bg_count[c] = 0\n", " sample_count[c] = 0\n", - " for s in background:\n", - " ancs = inferred_types(s)\n", - " for a in ancs.intersection(hypotheses):\n", - " bg_count[a] = bg_count[a]+1\n", - " for s in subjects:\n", - " for a in inferred_types(s):\n", - " if a in hypotheses:\n", - " sample_count[a] = sample_count[a]+1\n", + " \n", + " #hard-coded\n", + " bg_count[\"GO:0006950\"] = len(gene_ids)\n", + " sample_count[\"GO:0006950\"] = len(gene_ids)\n", + " \n", + " #ADD BACK IN LATER\n", + " #for s in background:\n", + " # ancs = inferred_types(s)\n", + " # for a in ancs.intersection(hypotheses):\n", + " # bg_count[a] = bg_count[a]+1\n", + " #for s in subjects:\n", + " # for a in inferred_types(s):\n", + " # if a in hypotheses:\n", + " # sample_count[a] = sample_count[a]+1\n", "\n", " hypotheses = [x for x in hypotheses if bg_count[x] > 1]\n", - " logger.info(\"Filtered hypotheses: {}\".format(hypotheses))\n", + " print(\"Filtered hypotheses: {}\".format(hypotheses))\n", " num_hypotheses = len(hypotheses)\n", " results = []\n", " for cls in hypotheses:\n", @@ -170,7 +438,7 @@ " c = bg_count[cls] - a\n", " d = (bg_size - bg_count[cls]) - b\n", " #logger.debug(\"ABCD=\"+str((cls,a,b,c,d,sample_size)))\n", - " _, p_uncorrected = sp.stats.fisher_exact( [[a, b], [c, d]], direction)\n", + " _, p_uncorrected = stats.fisher_exact( [[a, b], [c, d]], direction)\n", " p = p_uncorrected * num_hypotheses\n", " if p>1.0:\n", " p=1.0\n", @@ -187,31 +455,48 @@ }, { "cell_type": "code", - "execution_count": 19, + "execution_count": 40, "id": "5dd830c9", "metadata": {}, "outputs": [ { - "ename": "TypeError", - "evalue": "'NoneType' object is not callable", - "output_type": "error", - "traceback": [ - "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m", - "\u001b[0;31mTypeError\u001b[0m Traceback (most recent call last)", - "Input \u001b[0;32mIn [19]\u001b[0m, in \u001b[0;36m\u001b[0;34m()\u001b[0m\n\u001b[1;32m 1\u001b[0m \u001b[38;5;66;03m## Run enrichment tests using all classes in ontology\u001b[39;00m\n\u001b[0;32m----> 2\u001b[0m enr \u001b[38;5;241m=\u001b[39m \u001b[43menrichment_test\u001b[49m\u001b[43m(\u001b[49m\u001b[43msubjects\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[43mgene_ids\u001b[49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mthreshold\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;241;43m0.00005\u001b[39;49m\u001b[43m,\u001b[49m\u001b[43m \u001b[49m\u001b[43mlabels\u001b[49m\u001b[38;5;241;43m=\u001b[39;49m\u001b[38;5;28;43;01mTrue\u001b[39;49;00m\u001b[43m)\u001b[49m\n", - "Input \u001b[0;32mIn [17]\u001b[0m, in \u001b[0;36menrichment_test\u001b[0;34m(subjects, background, hypotheses, inferred_types, ontology_labels, threshold, labels, direction)\u001b[0m\n\u001b[1;32m 36\u001b[0m sample_size \u001b[38;5;241m=\u001b[39m \u001b[38;5;28mlen\u001b[39m(subjects)\n\u001b[1;32m 37\u001b[0m \u001b[38;5;28;01mfor\u001b[39;00m s \u001b[38;5;129;01min\u001b[39;00m subjects:\n\u001b[0;32m---> 38\u001b[0m potential_hypotheses\u001b[38;5;241m.\u001b[39mupdate(\u001b[43minferred_types\u001b[49m\u001b[43m(\u001b[49m\u001b[43ms\u001b[49m\u001b[43m)\u001b[49m)\n\u001b[1;32m 39\u001b[0m \u001b[38;5;28;01mif\u001b[39;00m hypotheses \u001b[38;5;129;01mis\u001b[39;00m \u001b[38;5;28;01mNone\u001b[39;00m:\n\u001b[1;32m 40\u001b[0m hypotheses \u001b[38;5;241m=\u001b[39m potential_hypotheses\n", - "\u001b[0;31mTypeError\u001b[0m: 'NoneType' object is not callable" + "name": "stdout", + "output_type": "stream", + "text": [ + "Hypotheses: ['GO:0006950']\n", + "Filtered hypotheses: ['GO:0006950']\n" ] } ], "source": [ "## Run enrichment tests using all classes in ontology\n", - "enr = enrichment_test(subjects=gene_ids, threshold=0.00005, labels=True)" + "enr = enrichment_test(subjects=gene_ids, background = None, hypotheses=hypotheses, threshold=0.1, labels=True)" + ] + }, + { + "cell_type": "code", + "execution_count": 41, + "id": "a088e7ba", + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "[]" + ] + }, + "execution_count": 41, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "enr" ] }, { "cell_type": "code", - "execution_count": null, + "execution_count": 36, "id": "00b3ee47", "metadata": {}, "outputs": [], diff --git a/notebooks/input/ma.obo b/notebooks/input/ma.obo new file mode 100644 index 000000000..a26aefb64 --- /dev/null +++ b/notebooks/input/ma.obo @@ -0,0 +1,19471 @@ +format-version: 1.2 +data-version: releases/2017-02-07 +date: 14:11:2014 14:12 +saved-by: terryh +auto-generated-by: OBO-Edit 2.3.1 +default-namespace: adult_mouse_anatomy.gxd +ontology: ma + +[Term] +id: MA:0000001 +name: mouse anatomical entity +synonym: "mouse anatomy" RELATED [] + +[Term] +id: MA:0000002 +name: spinal cord grey matter +xref: EMAPS:3579228 +is_a: MA:0001112 ! grey matter +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0000003 +name: organ system +xref: EMAPS:1610328 +is_a: MA:0003000 ! anatomical structure +relationship: part_of MA:0002405 ! postnatal mouse + +[Term] +id: MA:0000004 +name: trunk +synonym: "body" RELATED [] +xref: EMAPS:3185728 +is_a: MA:0002433 ! anatomic region + +[Term] +id: MA:0000005 +name: body cavity or lining +xref: EMAPS:1606028 +is_a: MA:0002433 ! anatomic region + +[Term] +id: MA:0000006 +name: head and neck +is_a: MA:0002433 ! anatomic region + +[Term] +id: MA:0000007 +name: limb +synonym: "extremity" RELATED [] +xref: EMAPS:1640528 +is_a: MA:0002433 ! anatomic region + +[Term] +id: MA:0000008 +name: tail +xref: EMAPS:1674828 +is_a: MA:0002433 ! anatomic region + +[Term] +id: MA:0000009 +name: adipose tissue +alt_id: MA:0000056 +synonym: "fat" EXACT [] +xref: EMAPS:3511228 +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0000010 +name: cardiovascular system +synonym: "circulatory system" RELATED [] +xref: EMAPS:1610428 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000011 +name: connective tissue +xref: EMAPS:3525128 +is_a: MA:0003002 ! tissue +relationship: part_of MA:0002887 ! set of connective tissues + +[Term] +id: MA:0000012 +name: endocrine system +xref: EMAPS:3530628 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000013 +name: hemolymphoid system +synonym: "haemolymphoid system" RELATED [] +xref: EMAPS:1876528 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000014 +name: integumental system +xref: EMAPS:1752428 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000015 +name: muscle organ +xref: EMAPS:3557728 +relationship: part_of MA:0002888 ! muscular system + +[Term] +id: MA:0000016 +name: nervous system +xref: EMAPS:1646928 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000017 +name: sensory organ +xref: EMAPS:3595528 +relationship: part_of MA:0002442 ! sensory organ system + +[Term] +id: MA:0000018 +name: skeletal system +xref: EMAPS:3577328 +relationship: part_of MA:0002418 ! musculoskeletal system + +[Term] +id: MA:0000019 +name: visceral organ system +xref: EMAPS:1624528 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0000020 +name: back of trunk +synonym: "body" RELATED [] +xref: EMAPS:3516228 +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000021 +name: abdominal segment of trunk +synonym: "abdomen/pelvis/perineum" RELATED [] +synonym: "lower body" RELATED [] +xref: EMAPS:3510428 +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000022 +name: thoracic segment of trunk +synonym: "thorax" RELATED [] +synonym: "upper body" RELATED [] +xref: EMAPS:3586228 +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000023 +name: head +xref: EMAPS:3185828 +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000024 +name: neck +xref: EMAPS:3558728 +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000025 +name: forelimb +xref: EMAPS:1741228 +is_a: MA:0000007 ! limb + +[Term] +id: MA:0000026 +name: hindlimb +xref: EMAPS:1745828 +is_a: MA:0000007 ! limb + +[Term] +id: MA:0000027 +name: lower back +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000028 +name: upper back +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000029 +name: abdomen +xref: EMAPS:3510228 +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000030 +name: pelvis +xref: EMAPS:3593128 +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000031 +name: chest +synonym: "thoracic body wall" RELATED [] +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000032 +name: thoracic cavity +is_a: MA:0002447 ! body cavity +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000033 +name: arm +xref: EMAPS:1741328 +is_a: MA:0002889 ! limb segment +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000034 +name: lower arm +synonym: "forearm" RELATED [] +xref: EMAPS:1741728 +is_a: MA:0002716 ! zeugopod +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000035 +name: upper arm +xref: EMAPS:1742428 +is_a: MA:0002717 ! stylopod +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000036 +name: elbow +xref: EMAPS:1741428 +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000037 +name: hand +synonym: "forepaw" RELATED [] +xref: EMAPS:1742828 +is_a: MA:0002714 ! autopod +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000038 +name: shoulder +xref: EMAPS:1742128 +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000039 +name: wrist +xref: EMAPS:3278428 +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000040 +name: carpus +xref: EMAPS:1912228 +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000041 +name: hand digit +xref: EMAPS:3264228 +is_a: MA:0000690 ! limb digit +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000042 +name: metacarpus +xref: EMAPS:3265428 +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000043 +name: ankle +xref: EMAPS:3278328 +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000044 +name: foot +synonym: "hindpaw" RELATED [] +xref: EMAPS:1745928 +is_a: MA:0002714 ! autopod +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000045 +name: hip +xref: EMAPS:1749028 +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000046 +name: knee +xref: EMAPS:1749328 +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000047 +name: leg +xref: EMAPS:1748928 +is_a: MA:0002889 ! limb segment +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000048 +name: foot digit +xref: EMAPS:3264928 +is_a: MA:0000690 ! limb digit +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000049 +name: metatarsus +xref: EMAPS:3294028 +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000050 +name: tarsus +xref: EMAPS:1913328 +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000051 +name: lower leg +xref: EMAPS:1749628 +is_a: MA:0002716 ! zeugopod +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000052 +name: upper leg +xref: EMAPS:1749928 +is_a: MA:0002717 ! stylopod +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000053 +name: pericardial cavity +xref: EMAPS:1613228 +is_a: MA:0002447 ! body cavity + +[Term] +id: MA:0000054 +name: peritoneal cavity +is_a: MA:0002447 ! body cavity + +[Term] +id: MA:0000055 +name: pleural cavity +xref: EMAPS:1677428 +is_a: MA:0002447 ! body cavity + +[Term] +id: MA:0000057 +name: brown adipose tissue +synonym: "brown fat" RELATED [] +xref: EMAPS:1920928 +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0000058 +name: white adipose tissue +synonym: "white fat" RELATED [] +xref: EMAPS:3592628 +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0000059 +name: blood +xref: EMAPS:1633228 +is_a: MA:0002450 ! body fluid or substance +relationship: part_of MA:0000010 ! cardiovascular system +relationship: part_of MA:0002434 ! hematopoietic system + +[Term] +id: MA:0000060 +name: blood vessel +synonym: "vasculature" RELATED [] +xref: EMAPS:3274328 +xref: EMAPS:3599328 +relationship: part_of MA:0002718 ! vascular system + +[Term] +id: MA:0000061 +name: arterial blood vessel +xref: EMAPS:3514428 +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0002719 ! arterial system + +[Term] +id: MA:0000062 +name: aorta +xref: EMAPS:1860128 +is_a: MA:0000061 ! arterial blood vessel +is_a: MA:0001902 ! thoracic cavity artery + +[Term] +id: MA:0000063 +name: arteriole +xref: EMAPS:3514628 +is_a: MA:0000061 ! arterial blood vessel + +[Term] +id: MA:0000064 +name: artery +xref: EMAPS:3514728 +is_a: MA:0000061 ! arterial blood vessel + +[Term] +id: MA:0000065 +name: capillary +xref: EMAPS:3519828 +is_a: MA:0000060 ! blood vessel + +[Term] +id: MA:0000066 +name: venous blood vessel +xref: EMAPS:3593228 +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0002720 ! venous system + +[Term] +id: MA:0000067 +name: vein +xref: EMAPS:3590628 +is_a: MA:0000066 ! venous blood vessel + +[Term] +id: MA:0000068 +name: vena cava +xref: EMAPS:1841528 +is_a: MA:0000066 ! venous blood vessel +is_a: MA:0001903 ! thoracic cavity vein + +[Term] +id: MA:0000069 +name: venous plexus +is_a: MA:0000066 ! venous blood vessel + +[Term] +id: MA:0000070 +name: venous sinus +is_a: MA:0000066 ! venous blood vessel + +[Term] +id: MA:0000071 +name: venule +xref: EMAPS:3591728 +is_a: MA:0000066 ! venous blood vessel + +[Term] +id: MA:0000072 +name: heart +xref: EMAPS:1610528 +relationship: part_of MA:0000010 ! cardiovascular system +relationship: part_of MA:0002449 ! heart/pericardium + +[Term] +id: MA:0000073 +name: heart atrium +xref: EMAPS:1668828 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000074 +name: heart left atrium +xref: EMAPS:1731528 +is_a: MA:0000073 ! heart atrium + +[Term] +id: MA:0000075 +name: heart right atrium +xref: EMAPS:1732128 +is_a: MA:0000073 ! heart atrium + +[Term] +id: MA:0000076 +name: heart endocardium +xref: EMAPS:3268628 +is_a: MA:0000717 ! cardiovascular system endothelium +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000077 +name: atrium endocardium +xref: EMAPS:3274528 +is_a: MA:0000076 ! heart endocardium +relationship: part_of MA:0000073 ! heart atrium + +[Term] +id: MA:0000078 +name: endocardial cushion +xref: EMAPS:1669628 +relationship: part_of MA:0000076 ! heart endocardium + +[Term] +id: MA:0000079 +name: ventricle endocardium +xref: EMAPS:3274728 +is_a: MA:0000076 ! heart endocardium +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0000080 +name: myocardium layer +relationship: part_of MA:0000072 ! heart +relationship: part_of MA:0000164 ! myocardium + +[Term] +id: MA:0000081 +name: atrium myocardium +xref: EMAPS:3274628 +is_a: MA:0000164 ! myocardium +relationship: part_of MA:0000073 ! heart atrium + +[Term] +id: MA:0000082 +name: ventricle myocardium +xref: EMAPS:3274828 +is_a: MA:0000164 ! myocardium +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0000083 +name: heart septum +xref: EMAPS:3540028 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000084 +name: interatrial septum +synonym: "atrial septum" RELATED [] +xref: EMAPS:1701128 +is_a: MA:0000083 ! heart septum +relationship: part_of MA:0000073 ! heart atrium + +[Term] +id: MA:0000085 +name: heart interventricular septum +synonym: "ventricular septum" RELATED [] +xref: EMAPS:1733328 +is_a: MA:0000083 ! heart septum +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0000086 +name: heart valve +xref: EMAPS:1786928 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000087 +name: aortic valve +xref: EMAPS:1787028 +is_a: MA:0002790 ! semilunar valve + +[Term] +id: MA:0000088 +name: mitral valve +synonym: "bicuspid valve" RELATED [] +xref: EMAPS:1787128 +is_a: MA:0002789 ! atrioventricular valve + +[Term] +id: MA:0000089 +name: pulmonary valve +xref: EMAPS:1787228 +is_a: MA:0002790 ! semilunar valve + +[Term] +id: MA:0000090 +name: tricuspid valve +xref: EMAPS:1787328 +is_a: MA:0002789 ! atrioventricular valve + +[Term] +id: MA:0000091 +name: heart ventricle +xref: EMAPS:1733128 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000092 +name: heart left ventricle +synonym: "left ventricle" RELATED [] +xref: EMAPS:1733728 +is_a: MA:0000091 ! heart ventricle + +[Term] +id: MA:0000093 +name: heart right ventricle +synonym: "right ventricle" RELATED [] +xref: EMAPS:1734028 +is_a: MA:0000091 ! heart ventricle + +[Term] +id: MA:0000094 +name: impulse conducting system +xref: EMAPS:3542828 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000095 +name: atrioventricular node +synonym: "AV node" RELATED [] +xref: EMAPS:3515328 +relationship: part_of MA:0000094 ! impulse conducting system + +[Term] +id: MA:0000096 +name: purkinje fiber +xref: EMAPS:3571828 +relationship: part_of MA:0000094 ! impulse conducting system + +[Term] +id: MA:0000097 +name: sinoatrial node +synonym: "SA node" RELATED [] +synonym: "sinuatrial node" RELATED [] +xref: EMAPS:3577228 +relationship: part_of MA:0000094 ! impulse conducting system + +[Term] +id: MA:0000098 +name: heart mesentery +synonym: "mesocardium" RELATED [] +xref: EMAPS:1621228 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000099 +name: pericardium +xref: EMAPS:1613328 +is_a: MA:0002448 ! cavity lining +relationship: part_of MA:0000053 ! pericardial cavity +relationship: part_of MA:0002449 ! heart/pericardium + +[Term] +id: MA:0000100 +name: outflow tract +xref: EMAPS:1634628 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000101 +name: outflow tract aortic component +xref: EMAPS:1732928 +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000102 +name: outflow tract pulmonary component +xref: EMAPS:1733028 +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000103 +name: truncus arteriosus +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000104 +name: cartilage tissue +xref: EMAPS:3273028 +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0000105 +name: cellular cartilage +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0000106 +name: costal cartilage +xref: EMAPS:3526228 +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0000107 +name: elastic cartilage +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0000108 +name: fibrocartilage +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0000109 +name: hyaline cartilage +xref: EMAPS:3541428 +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0000110 +name: intervertebral disc +alt_id: MA:0001515 +xref: EMAPS:3273928 +is_a: MA:0000011 ! connective tissue +relationship: part_of MA:0001514 ! joint of vertebral body + +[Term] +id: MA:0000111 +name: annulus fibrosus +alt_id: MA:0001516 +xref: EMAPS:3267028 +relationship: part_of MA:0000110 ! intervertebral disc + +[Term] +id: MA:0000112 +name: nucleus pulposus +alt_id: MA:0001517 +xref: EMAPS:1800828 +relationship: part_of MA:0000110 ! intervertebral disc + +[Term] +id: MA:0000113 +name: ligament +xref: EMAPS:3549328 +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0000114 +name: synovium +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0000115 +name: tendon +xref: EMAPS:3585428 +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0000116 +name: adrenal gland +synonym: "suprarenal gland" RELATED [] +xref: EMAPS:1842628 +is_a: MA:0000522 ! abdomen organ +is_a: MA:0002563 ! endocrine gland + +[Term] +id: MA:0000117 +name: adrenal gland capsule +relationship: part_of MA:0000116 ! adrenal gland + +[Term] +id: MA:0000118 +name: adrenal gland cortex +xref: EMAPS:1842728 +relationship: part_of MA:0000116 ! adrenal gland + +[Term] +id: MA:0000119 +name: adrenal gland medulla +xref: EMAPS:1842828 +relationship: part_of MA:0000116 ! adrenal gland + +[Term] +id: MA:0000120 +name: pancreas +xref: EMAPS:1750328 +is_a: MA:0000522 ! abdomen organ + +[Term] +id: MA:0000121 +name: pancreas body +synonym: "pancreas corpus" RELATED [] +xref: EMAPS:1750428 +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0000122 +name: pancreas head +xref: EMAPS:1750728 +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0000123 +name: pancreas tail +xref: EMAPS:1751128 +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0000124 +name: pancreatic duct +xref: EMAPS:3295228 +relationship: part_of MA:0002415 ! exocrine pancreas + +[Term] +id: MA:0000125 +name: dorsal pancreatic duct +xref: EMAPS:3295328 +is_a: MA:0000124 ! pancreatic duct + +[Term] +id: MA:0000126 +name: ventral pancreatic duct +xref: EMAPS:1751028 +is_a: MA:0000124 ! pancreatic duct + +[Term] +id: MA:0000127 +name: pancreatic islet +synonym: "islet of langerhans" RELATED [] +xref: EMAPS:3292728 +relationship: part_of MA:0001582 ! endocrine pancreas + +[Term] +id: MA:0000128 +name: parathyroid gland +xref: EMAPS:3281228 +is_a: MA:0000589 ! neck organ +is_a: MA:0002563 ! endocrine gland + +[Term] +id: MA:0000129 +name: thyroid gland +xref: EMAPS:1706828 +is_a: MA:0000589 ! neck organ +is_a: MA:0002563 ! endocrine gland + +[Term] +id: MA:0000130 +name: thyroglossal duct +xref: EMAPS:1707028 +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000131 +name: thyroid gland lobe +xref: EMAPS:1819628 +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000132 +name: thyroid gland medulla +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000133 +name: cerebral hemisphere +synonym: "cerebrum" RELATED [] +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000134 +name: bone marrow +xref: EMAPS:3276028 +relationship: part_of MA:0001459 ! bone +relationship: part_of MA:0002434 ! hematopoietic system +relationship: part_of MA:0002711 ! immune system + +[Term] +id: MA:0000135 +name: bronchus associated lymphoid tissue +synonym: "BALT" RELATED [] +is_a: MA:0000140 ! mucosa associated lymphoid tissue + +[Term] +id: MA:0000136 +name: gut associated lymphoid tissue +synonym: "GALT" RELATED [] +is_a: MA:0000140 ! mucosa associated lymphoid tissue + +[Term] +id: MA:0000137 +name: peyer's patch +xref: EMAPS:1902828 +is_a: MA:0000136 ! gut associated lymphoid tissue +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0000138 +name: lymphatic vessel +xref: EMAPS:3553228 +relationship: part_of MA:0002961 ! lymphatic system + +[Term] +id: MA:0000139 +name: lymph node +xref: EMAPS:3552328 +relationship: part_of MA:0002435 ! lymphoid system + +[Term] +id: MA:0000140 +name: mucosa associated lymphoid tissue +synonym: "MALT" RELATED [] +is_a: MA:0002436 ! lymphoid tissue + +[Term] +id: MA:0000141 +name: spleen +xref: EMAPS:1876728 +is_a: MA:0000522 ! abdomen organ +is_a: MA:0002962 ! hemolymphoid system gland +relationship: part_of MA:0002434 ! hematopoietic system +relationship: part_of MA:0002711 ! immune system + +[Term] +id: MA:0000142 +name: thymus +xref: EMAPS:1876828 +is_a: MA:0000557 ! thoracic cavity organ +is_a: MA:0002962 ! hemolymphoid system gland +relationship: part_of MA:0002434 ! hematopoietic system +relationship: part_of MA:0002711 ! immune system + +[Term] +id: MA:0000143 +name: tonsil +xref: EMAPS:3587128 +is_a: MA:0000752 ! oropharyngeal lymphoid tissue +relationship: part_of MA:0000341 ! oral region + +[Term] +id: MA:0000144 +name: integumental system gland +xref: EMAPS:1775828 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0000145 +name: mammary gland +xref: EMAPS:1775928 +is_a: MA:0000144 ! integumental system gland +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0000146 +name: skin gland +xref: EMAPS:3577428 +is_a: MA:0000144 ! integumental system gland +relationship: part_of MA:0000151 ! skin + +[Term] +id: MA:0000147 +name: apocrine sweat gland +is_a: MA:0000146 ! skin gland +is_a: MA:0003040 ! apocrine gland + +[Term] +id: MA:0000148 +name: skin mucous gland +xref: EMAPS:3577528 +is_a: MA:0000146 ! skin gland + +[Term] +id: MA:0000149 +name: pilosebaceous gland +is_a: MA:0002565 ! sebaceous gland + +[Term] +id: MA:0000150 +name: sweat gland +xref: EMAPS:3584428 +is_a: MA:0000146 ! skin gland +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0000151 +name: skin +xref: EMAPS:1752528 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0000152 +name: dermis +xref: EMAPS:1752728 +relationship: part_of MA:0000151 ! skin + +[Term] +id: MA:0000153 +name: epidermis +xref: EMAPS:1752828 +relationship: part_of MA:0000151 ! skin + +[Term] +id: MA:0000154 +name: hair follicle +xref: EMAPS:1877128 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0000155 +name: coat hair +xref: EMAPS:1876928 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0000156 +name: hair cortex +xref: EMAPS:3538728 +relationship: part_of MA:0000155 ! coat hair + +[Term] +id: MA:0000157 +name: hair cuticle +xref: EMAPS:3538828 +relationship: part_of MA:0000155 ! coat hair + +[Term] +id: MA:0000158 +name: hair medulla +xref: EMAPS:3538928 +relationship: part_of MA:0000155 ! coat hair + +[Term] +id: MA:0000159 +name: hair shaft +relationship: part_of MA:0000155 ! coat hair +relationship: part_of MA:0000160 ! coat hair follicle + +[Term] +id: MA:0000160 +name: coat hair follicle +xref: EMAPS:3524628 +is_a: MA:0000154 ! hair follicle + +[Term] +id: MA:0000161 +name: coat hair bulb +xref: EMAPS:1877028 +relationship: part_of MA:0000160 ! coat hair follicle + +[Term] +id: MA:0000162 +name: hair root sheath +xref: EMAPS:1877228 +relationship: part_of MA:0000161 ! coat hair bulb + +[Term] +id: MA:0000163 +name: vibrissa +synonym: "whisker" RELATED [] +xref: EMAPS:1752928 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0000164 +name: myocardium +synonym: "cardiac muscle" RELATED [] +xref: EMAPS:3268828 +relationship: part_of MA:0002888 ! muscular system + +[Term] +id: MA:0000165 +name: set of skeletal muscles +xref: EMAPS:3557828 +relationship: part_of MA:0002888 ! muscular system + +[Term] +id: MA:0000166 +name: smooth muscle tissue +alt_id: MA:0002440 +xref: EMAPS:3271728 +is_a: MA:0002437 ! muscle tissue + +[Term] +id: MA:0000167 +name: central nervous system +xref: EMAPS:1647028 +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0000168 +name: brain +xref: EMAPS:1689428 +is_a: MA:0000581 ! head organ +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0000169 +name: brainstem +synonym: "brain stem" RELATED [] +xref: EMAPS:3267828 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000170 +name: forebrain +synonym: "prosencephalon" RELATED [] +xref: EMAPS:1689528 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000171 +name: diencephalon +xref: EMAPS:1689628 +relationship: part_of MA:0000170 ! forebrain + +[Term] +id: MA:0000172 +name: epithalamus +xref: EMAPS:1753228 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000173 +name: hypothalamus +xref: EMAPS:1753628 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000174 +name: mammillary body +xref: EMAPS:3554228 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000175 +name: pineal gland +synonym: "corpus pineale" RELATED [] +synonym: "epiphysis cerebri" RELATED [] +synonym: "pineal body" RELATED [] +xref: EMAPS:1877828 +is_a: MA:0002943 ! secretory circumventricular organ +relationship: part_of MA:0000172 ! epithalamus + +[Term] +id: MA:0000176 +name: pituitary gland +synonym: "hypophysis cerebri" RELATED [] +xref: EMAPS:3599828 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000177 +name: adenohypophysis +xref: EMAPS:1751428 +relationship: part_of MA:0000176 ! pituitary gland + +[Term] +id: MA:0000178 +name: neurohypophysis +xref: EMAPS:1751928 +is_a: MA:0002943 ! secretory circumventricular organ +relationship: part_of MA:0000176 ! pituitary gland + +[Term] +id: MA:0000179 +name: thalamus +xref: EMAPS:1754028 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000180 +name: dorsal thalamus +xref: EMAPS:3529528 +relationship: part_of MA:0000179 ! thalamus + +[Term] +id: MA:0000181 +name: ventral thalamus +synonym: "subthalamus" RELATED [] +xref: EMAPS:3591528 +relationship: part_of MA:0000179 ! thalamus + +[Term] +id: MA:0000182 +name: 3rd ventricle +synonym: "third ventricle" RELATED [] +xref: EMAPS:1690028 +is_a: MA:0000818 ! brain ventricle +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000183 +name: telencephalon +synonym: "cerebrum" RELATED [] +synonym: "telencephalic vesicle" RELATED [] +xref: EMAPS:1691028 +relationship: part_of MA:0000170 ! forebrain + +[Term] +id: MA:0000184 +name: basal ganglia +synonym: "basal nucleus" RELATED [] +xref: EMAPS:3267328 +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000185 +name: cerebral cortex +xref: EMAPS:1754428 +relationship: part_of MA:0000133 ! cerebral hemisphere + +[Term] +id: MA:0000186 +name: neocortex layer +synonym: "cerebral cortex layer" RELATED [] +xref: EMAPS:3558828 +relationship: part_of MA:0002754 ! neocortex + +[Term] +id: MA:0000187 +name: neocortex region +synonym: "cerebral cortex region" RELATED [] +xref: EMAPS:3558928 +relationship: part_of MA:0002754 ! neocortex + +[Term] +id: MA:0000188 +name: corpus callosum +xref: EMAPS:3525328 +is_a: MA:0002721 ! intercerebral commissure + +[Term] +id: MA:0000189 +name: hippocampal formation +synonym: "archipallium" RELATED [] +synonym: "primal cortex" RELATED [] +xref: EMAPS:3540528 +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000190 +name: dentate gyrus +xref: EMAPS:1903728 +relationship: part_of MA:0000189 ! hippocampal formation + +[Term] +id: MA:0000191 +name: hippocampus +synonym: "ammon's horn" RELATED [] +xref: EMAPS:3284528 +relationship: part_of MA:0000189 ! hippocampal formation + +[Term] +id: MA:0000192 +name: lateral ventricle +xref: EMAPS:1691428 +is_a: MA:0000818 ! brain ventricle +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000193 +name: olfactory cortex +synonym: "olfactory lobe" RELATED [] +xref: EMAPS:1777928 +relationship: part_of MA:0002413 ! olfactory lobe + +[Term] +id: MA:0000194 +name: main olfactory bulb +synonym: "main olfactory bulb" RELATED [] +xref: EMAPS:3280928 +relationship: part_of MA:0002413 ! olfactory lobe + +[Term] +id: MA:0000195 +name: hindbrain +synonym: "rhombencephalon" RELATED [] +xref: EMAPS:1691628 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000196 +name: 4th ventricle +synonym: "fourth ventricle" RELATED [] +xref: EMAPS:1691728 +is_a: MA:0000818 ! brain ventricle +relationship: part_of MA:0000195 ! hindbrain + +[Term] +id: MA:0000197 +name: metencephalon +xref: EMAPS:1707128 +relationship: part_of MA:0000195 ! hindbrain + +[Term] +id: MA:0000198 +name: cerebellum +xref: EMAPS:1778728 +relationship: part_of MA:0000197 ! metencephalon + +[Term] +id: MA:0000199 +name: cerebellar cortex +xref: EMAPS:3521128 +relationship: part_of MA:0000198 ! cerebellum + +[Term] +id: MA:0000200 +name: cerebellum hemisphere +xref: EMAPS:3521828 +relationship: part_of MA:0000199 ! cerebellar cortex + +[Term] +id: MA:0000201 +name: cerebellar layer +xref: EMAPS:3521228 +relationship: part_of MA:0000199 ! cerebellar cortex + +[Term] +id: MA:0000202 +name: cerebellum vermis +xref: EMAPS:3521428 +relationship: part_of MA:0000199 ! cerebellar cortex + +[Term] +id: MA:0000203 +name: deep cerebellar nucleus +xref: EMAPS:3527228 +relationship: part_of MA:0000198 ! cerebellum + +[Term] +id: MA:0000204 +name: pons +xref: EMAPS:1756328 +relationship: part_of MA:0000169 ! brainstem +relationship: part_of MA:0000197 ! metencephalon + +[Term] +id: MA:0000205 +name: myelencephalon +xref: EMAPS:1755028 +relationship: part_of MA:0000195 ! hindbrain + +[Term] +id: MA:0000206 +name: medulla oblongata +xref: EMAPS:1755028 +relationship: part_of MA:0000169 ! brainstem +relationship: part_of MA:0000205 ! myelencephalon + +[Term] +id: MA:0000207 +name: midbrain +synonym: "mesencephalon" RELATED [] +xref: EMAPS:1697428 +relationship: part_of MA:0000168 ! brain +relationship: part_of MA:0000169 ! brainstem + +[Term] +id: MA:0000208 +name: cerebral aqueduct +xref: EMAPS:1779528 +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0000209 +name: midbrain periaqueductal grey +synonym: "central grey" RELATED [] +xref: EMAPS:3556928 +is_a: MA:0002895 ! periaqueductal grey +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0000210 +name: substantia nigra +xref: EMAPS:3583528 +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0000211 +name: tectum +xref: EMAPS:1905128 +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0000212 +name: tegmentum +xref: EMAPS:1821528 +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0000213 +name: cranial ganglion/nerve +is_a: MA:0000580 ! head nerve/ganglion +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0000214 +name: cranial ganglion +xref: EMAPS:1665928 +is_a: MA:0002406 ! ganglion +relationship: part_of MA:0000213 ! cranial ganglion/nerve + +[Term] +id: MA:0000215 +name: cranial nerve +xref: EMAPS:1726428 +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000213 ! cranial ganglion/nerve + +[Term] +id: MA:0000216 +name: spinal cord +xref: EMAPS:1757728 +is_a: MA:0001901 ! back organ +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0000217 +name: nerve +xref: EMAPS:3280828 +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0000218 +name: peripheral nervous system +xref: EMAPS:1666528 +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0000219 +name: autonomic nervous system +xref: EMAPS:1698428 +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0000220 +name: autonomic ganglion +xref: EMAPS:1822128 +is_a: MA:0001161 ! peripheral nervous system ganglion +relationship: part_of MA:0000219 ! autonomic nervous system + +[Term] +id: MA:0000221 +name: autonomic nerve plexus +xref: EMAPS:1822428 +is_a: MA:0002407 ! nerve plexus +relationship: part_of MA:0000219 ! autonomic nervous system + +[Term] +id: MA:0000222 +name: enteric nervous system +xref: EMAPS:2692228 +relationship: part_of MA:0000219 ! autonomic nervous system + +[Term] +id: MA:0000223 +name: parasympathetic nervous system +xref: EMAPS:1727028 +relationship: part_of MA:0000219 ! autonomic nervous system + +[Term] +id: MA:0000224 +name: parasympathetic nerve +xref: EMAPS:1727128 +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000223 ! parasympathetic nervous system + +[Term] +id: MA:0000225 +name: sympathetic nervous system +xref: EMAPS:1698528 +relationship: part_of MA:0000219 ! autonomic nervous system + +[Term] +id: MA:0000226 +name: sympathetic ganglion +xref: EMAPS:1715728 +is_a: MA:0000220 ! autonomic ganglion +relationship: part_of MA:0000225 ! sympathetic nervous system + +[Term] +id: MA:0000227 +name: sympathetic nerve trunk +xref: EMAPS:3584528 +is_a: MA:0002408 ! nerve trunk +relationship: part_of MA:0000225 ! sympathetic nervous system + +[Term] +id: MA:0000228 +name: peripheral nerve +xref: EMAPS:3281528 +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0000229 +name: peripheral nerve trunk +xref: EMAPS:1698628 +is_a: MA:0002408 ! nerve trunk +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0000230 +name: peripheral nervous system spinal component +xref: EMAPS:1666628 +xref: EMAPS:3579628 +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0000231 +name: spinal ganglion +xref: EMAPS:1666728 +is_a: MA:0002566 ! sensory ganglion +relationship: part_of MA:0000230 ! peripheral nervous system spinal component + +[Term] +id: MA:0000232 +name: dorsal root ganglion +xref: EMAPS:1666828 +is_a: MA:0000231 ! spinal ganglion + +[Term] +id: MA:0000233 +name: spinal nerve +xref: EMAPS:1698928 +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000230 ! peripheral nervous system spinal component + +[Term] +id: MA:0000234 +name: segmental spinal nerve +xref: EMAPS:1699028 +is_a: MA:0000233 ! spinal nerve + +[Term] +id: MA:0000235 +name: spinal nerve plexus +xref: EMAPS:1698728 +is_a: MA:0002407 ! nerve plexus +relationship: part_of MA:0000230 ! peripheral nervous system spinal component + +[Term] +id: MA:0000236 +name: ear +synonym: "auditory/vestibular system" RELATED [] +xref: EMAPS:1619328 +is_a: MA:0000017 ! sensory organ +is_a: MA:0000581 ! head organ +relationship: part_of MA:0002443 ! auditory system +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0000237 +name: inner ear +synonym: "labyrinth" RELATED [] +xref: EMAPS:1619428 +relationship: part_of MA:0000236 ! ear + +[Term] +id: MA:0000238 +name: bony labyrinth +synonym: "osseus labyrinth" RELATED [] +relationship: part_of MA:0000237 ! inner ear +relationship: part_of MA:0001477 ! temporal bone petrous part + +[Term] +id: MA:0000239 +name: osseus cochlea +xref: EMAPS:3562028 +relationship: part_of MA:0000238 ! bony labyrinth +relationship: part_of MA:0000240 ! cochlea + +[Term] +id: MA:0000240 +name: cochlea +xref: EMAPS:1759728 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000241 +name: endolymphatic appendage +xref: EMAPS:1699428 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000242 +name: membranous labyrinth +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000243 +name: cochlear duct +xref: EMAPS:1759828 +relationship: part_of MA:0002809 ! cochlear labyrinth + +[Term] +id: MA:0000244 +name: ductus reuniens +xref: EMAPS:1728728 +relationship: part_of MA:0000242 ! membranous labyrinth + +[Term] +id: MA:0000245 +name: vestibular labyrinth +synonym: "vestibular apparatus" RELATED [] +xref: EMAPS:1781528 +relationship: part_of MA:0000242 ! membranous labyrinth + +[Term] +id: MA:0000246 +name: saccule +xref: EMAPS:1729028 +is_a: MA:0002841 ! otolith organ +relationship: part_of MA:0000245 ! vestibular labyrinth + +[Term] +id: MA:0000247 +name: utricle +xref: EMAPS:1729328 +is_a: MA:0002841 ! otolith organ +relationship: part_of MA:0000245 ! vestibular labyrinth + +[Term] +id: MA:0000248 +name: perilymphatic channel +synonym: "perilymphatic space" RELATED [] +xref: EMAPS:3567728 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000249 +name: semicircular canal +xref: EMAPS:3283228 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000250 +name: osseus semicircular canal +relationship: part_of MA:0000238 ! bony labyrinth +relationship: part_of MA:0000249 ! semicircular canal + +[Term] +id: MA:0000251 +name: semicircular duct +synonym: "membranous semicircular canal" RELATED [] +xref: EMAPS:3283028 +relationship: part_of MA:0000245 ! vestibular labyrinth +relationship: part_of MA:0000249 ! semicircular canal + +[Term] +id: MA:0000252 +name: otic capsule +synonym: "periotic capsule" RELATED [] +xref: EMAPS:1759628 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0000253 +name: middle ear +synonym: "tympanic cavity" RELATED [] +xref: EMAPS:1700028 +relationship: part_of MA:0000236 ! ear + +[Term] +id: MA:0000254 +name: auditory bone +synonym: "auditory ossicle" RELATED [] +synonym: "ear bone" RELATED [] +xref: EMAPS:1782428 +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0000255 +name: auditory tube +synonym: "eustachian tube" RELATED [] +synonym: "pharyngo-tympanic tube" RELATED [] +synonym: "pharyngotympanic tube" RELATED [] +xref: EMAPS:1760128 +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0000256 +name: tympanic cavity muscle +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0000257 +name: tympanic membrane +xref: EMAPS:1906228 +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0000258 +name: outer ear +synonym: "external ear" RELATED [] +xref: EMAPS:1699128 +relationship: part_of MA:0000236 ! ear + +[Term] +id: MA:0000259 +name: auricle +synonym: "pinna" RELATED [] +xref: EMAPS:1758928 +xref: EMAPS:3515728 +relationship: part_of MA:0000258 ! outer ear + +[Term] +id: MA:0000260 +name: external acoustic meatus +synonym: "external auditory meatus" RELATED [] +xref: EMAPS:1758828 +relationship: part_of MA:0000258 ! outer ear + +[Term] +id: MA:0000261 +name: eye +xref: EMAPS:1619828 +is_a: MA:0000017 ! sensory organ +is_a: MA:0000581 ! head organ +relationship: part_of MA:0002444 ! visual system +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0000262 +name: eye anterior chamber +xref: EMAPS:1823128 +is_a: MA:0002459 ! eye chamber +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0000263 +name: choroid +xref: EMAPS:1907728 +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0000264 +name: ciliary body +xref: EMAPS:1906528 +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0000265 +name: conjunctiva +synonym: "conjunctival sac" RELATED [] +xref: EMAPS:1823328 +relationship: part_of MA:0002484 ! eye anterior segment +relationship: part_of MA:0002486 ! eye surface + +[Term] +id: MA:0000266 +name: cornea +synonym: "tunica cornea" RELATED [] +xref: EMAPS:1716128 +relationship: part_of MA:0002484 ! eye anterior segment +relationship: part_of MA:0002486 ! eye surface + +[Term] +id: MA:0000267 +name: eye gland +xref: EMAPS:3533428 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0000268 +name: eyelid +synonym: "palpebra" RELATED [] +xref: EMAPS:1782928 +relationship: part_of MA:0002486 ! eye surface + +[Term] +id: MA:0000269 +name: eyelid muscle +is_a: MA:0000271 ! eye muscle +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0000270 +name: eyelid tarsus +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0000271 +name: eye muscle +xref: EMAPS:3533528 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0000272 +name: hyaloid cavity +xref: EMAPS:1730228 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0000273 +name: iris +xref: EMAPS:1915428 +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0000274 +name: lacrimal apparatus +xref: EMAPS:3546228 +relationship: part_of MA:0002486 ! eye surface + +[Term] +id: MA:0000275 +name: lens +xref: EMAPS:1783828 +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0000276 +name: retina +xref: EMAPS:1716828 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0000277 +name: neural retinal epithelium +xref: EMAPS:1859028 +is_a: MA:0003173 ! retina epithelium + +[Term] +id: MA:0000278 +name: optic disc +xref: EMAPS:1823828 +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0000279 +name: pigmented retinal epithelium +xref: EMAPS:1717228 +is_a: MA:0003173 ! retina epithelium + +[Term] +id: MA:0000280 +name: sclera +xref: EMAPS:1902728 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0000281 +name: nose +xref: EMAPS:1654228 +is_a: MA:0000017 ! sensory organ +is_a: MA:0000581 ! head organ +relationship: part_of MA:0000327 ! respiratory system +relationship: part_of MA:0001910 ! snout +relationship: part_of MA:0002445 ! olfactory system + +[Term] +id: MA:0000282 +name: naris +xref: EMAPS:1784728 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000283 +name: nasal capsule +xref: EMAPS:1785228 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000284 +name: nasal cavity +xref: EMAPS:1760428 +relationship: part_of MA:0000281 ! nose +relationship: part_of MA:0000442 ! upper respiratory tract + +[Term] +id: MA:0000285 +name: nasal septum +xref: EMAPS:1760828 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000286 +name: nasal turbinate +xref: EMAPS:2509328 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000287 +name: olfactory gland +synonym: "olfactory gland of bowman" RELATED [] +xref: EMAPS:3561328 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000288 +name: olfactory receptor nerve +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000289 +name: vomeronasal organ +synonym: "organ of jacobsen" RELATED [] +xref: EMAPS:1761228 +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0000290 +name: appendicular skeleton +xref: EMAPS:3272928 +relationship: part_of MA:0003006 ! skeleton + +[Term] +id: MA:0000291 +name: girdle bone +xref: EMAPS:3537928 +relationship: part_of MA:0000290 ! appendicular skeleton + +[Term] +id: MA:0000292 +name: pectoral girdle bone +xref: EMAPS:3566928 +is_a: MA:0000291 ! girdle bone +is_a: MA:0000547 ! chest bone + +[Term] +id: MA:0000293 +name: pelvic girdle bone +xref: EMAPS:1802828 +is_a: MA:0000291 ! girdle bone +is_a: MA:0000532 ! pelvis bone + +[Term] +id: MA:0000295 +name: carpal/tarsal bone +is_a: MA:0000688 ! limb bone + +[Term] +id: MA:0000296 +name: carpal bone +xref: EMAPS:2505628 +is_a: MA:0000295 ! carpal/tarsal bone +is_a: MA:0000619 ! hand bone +relationship: part_of MA:0000040 ! carpus + +[Term] +id: MA:0000297 +name: tarsal bone +xref: EMAPS:2507228 +is_a: MA:0000295 ! carpal/tarsal bone +is_a: MA:0000643 ! foot bone +relationship: part_of MA:0000050 ! tarsus + +[Term] +id: MA:0000298 +name: limb long bone +xref: EMAPS:3549528 +is_a: MA:0000688 ! limb bone +is_a: MA:0002802 ! long bone + +[Term] +id: MA:0000299 +name: forelimb long bone +xref: EMAPS:3535028 +is_a: MA:0000298 ! limb long bone + +[Term] +id: MA:0000300 +name: hindlimb long bone +xref: EMAPS:3540328 +is_a: MA:0000298 ! limb long bone + +[Term] +id: MA:0000301 +name: metacarpal/metatarsal bone +is_a: MA:0000688 ! limb bone + +[Term] +id: MA:0000302 +name: metacarpal bone +is_a: MA:0000301 ! metacarpal/metatarsal bone +is_a: MA:0000619 ! hand bone +relationship: part_of MA:0000042 ! metacarpus + +[Term] +id: MA:0000303 +name: metatarsal bone +is_a: MA:0000301 ! metacarpal/metatarsal bone +is_a: MA:0000643 ! foot bone +relationship: part_of MA:0000049 ! metatarsus + +[Term] +id: MA:0000304 +name: phalanx +xref: EMAPS:3261428 +is_a: MA:0000688 ! limb bone + +[Term] +id: MA:0000305 +name: foot phalanx +xref: EMAPS:3294128 +is_a: MA:0000304 ! phalanx +is_a: MA:0000646 ! foot digit bone + +[Term] +id: MA:0000306 +name: hand phalanx +xref: EMAPS:3265028 +is_a: MA:0000304 ! phalanx +is_a: MA:0000622 ! hand digit bone + +[Term] +id: MA:0000307 +name: other limb bone +is_a: MA:0000688 ! limb bone + +[Term] +id: MA:0000308 +name: axial skeleton +xref: EMAPS:1721428 +relationship: part_of MA:0003006 ! skeleton + +[Term] +id: MA:0000309 +name: vertebra +xref: EMAPS:3274028 +relationship: part_of MA:0002416 ! vertebral column + +[Term] +id: MA:0000310 +name: caudal vertebra +synonym: "tail vertebra" RELATED [] +xref: EMAPS:1837428 +is_a: MA:0000309 ! vertebra +is_a: MA:0000532 ! pelvis bone +is_a: MA:0000696 ! tail bone +relationship: part_of MA:0003158 ! axial skeleton tail region + +[Term] +id: MA:0000311 +name: cervical vertebra +xref: EMAPS:1767428 +is_a: MA:0000584 ! neck bone +is_a: MA:0002869 ! presacral vertebra +relationship: part_of MA:0003154 ! axial skeleton cervical region + +[Term] +id: MA:0000312 +name: lumbar vertebra +xref: EMAPS:1800728 +is_a: MA:0000500 ! lower back bone +is_a: MA:0002869 ! presacral vertebra +relationship: part_of MA:0003156 ! axial skeleton lumbar region + +[Term] +id: MA:0000313 +name: sacral vertebra +synonym: "sacrum" RELATED [] +xref: EMAPS:1833628 +is_a: MA:0000309 ! vertebra +is_a: MA:0000532 ! pelvis bone + +[Term] +id: MA:0000314 +name: thoracic vertebra +xref: EMAPS:1801128 +is_a: MA:0000506 ! upper back bone +is_a: MA:0002869 ! presacral vertebra +relationship: part_of MA:0003155 ! axial skeleton thoracic region + +[Term] +id: MA:0000315 +name: rib +xref: EMAPS:1801028 +is_a: MA:0000547 ! chest bone +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0000316 +name: cranium +synonym: "cranial bone" RELATED [] +synonym: "skull" RELATED [] +xref: EMAPS:1768028 +relationship: part_of MA:0000308 ! axial skeleton +relationship: part_of MA:0000576 ! head bone + +[Term] +id: MA:0000317 +name: chondrocranium +synonym: "calvarium" RELATED [] +synonym: "neurocranium" RELATED [] +xref: EMAPS:1768128 +relationship: part_of MA:0000316 ! cranium + +[Term] +id: MA:0000318 +name: viscerocranium +synonym: "facial bone" RELATED [] +xref: EMAPS:1802228 +relationship: part_of MA:0000316 ! cranium + +[Term] +id: MA:0000319 +name: joint +xref: EMAPS:3545628 +relationship: part_of MA:0003007 ! articular system + +[Term] +id: MA:0000320 +name: cartilaginous joint +is_a: MA:0000319 ! joint + +[Term] +id: MA:0000321 +name: fibrous joint +xref: EMAPS:3534428 +is_a: MA:0000319 ! joint + +[Term] +id: MA:0000322 +name: synovial joint +is_a: MA:0000319 ! joint + +[Term] +id: MA:0000323 +name: alimentary system +synonym: "alimentary tract" RELATED [] +xref: EMAPS:1624628 +relationship: part_of MA:0002431 ! digestive system + +[Term] +id: MA:0000324 +name: hepatobiliary system +synonym: "liver/biliary system" RELATED [] +xref: EMAPS:1684028 +relationship: part_of MA:0002431 ! digestive system + +[Term] +id: MA:0000325 +name: urinary system +synonym: "excretory system" RELATED [] +synonym: "urinary system" RELATED [] +xref: EMAPS:1736628 +is_a: MA:0000019 ! visceral organ system + +[Term] +id: MA:0000326 +name: reproductive system +xref: EMAPS:1738128 +is_a: MA:0000019 ! visceral organ system + +[Term] +id: MA:0000327 +name: respiratory system +xref: EMAPS:1672728 +is_a: MA:0000019 ! visceral organ system + +[Term] +id: MA:0000328 +name: intestine +xref: EMAPS:3287428 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0000329 +name: anal region +xref: EMAPS:1683128 +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0000330 +name: anal canal +xref: EMAPS:1825628 +relationship: part_of MA:0000329 ! anal region + +[Term] +id: MA:0000331 +name: anus +relationship: part_of MA:0000329 ! anal region + +[Term] +id: MA:0000332 +name: ileocaecal junction +synonym: "ileocecal junction" RELATED [] +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0000333 +name: large intestine +xref: EMAPS:1925228 +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0000334 +name: cecum +synonym: "caecum" RELATED [] +xref: EMAPS:3519728 +relationship: part_of MA:0000333 ! large intestine + +[Term] +id: MA:0000335 +name: colon +xref: EMAPS:1893928 +relationship: part_of MA:0000333 ! large intestine + +[Term] +id: MA:0000336 +name: rectum +xref: EMAPS:1789628 +relationship: part_of MA:0000333 ! large intestine + +[Term] +id: MA:0000337 +name: small intestine +xref: EMAPS:3283428 +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0000338 +name: duodenum +xref: EMAPS:1885228 +is_a: MA:0000337 ! small intestine + +[Term] +id: MA:0000339 +name: ileum +xref: EMAPS:3276428 +is_a: MA:0000337 ! small intestine + +[Term] +id: MA:0000340 +name: jejunum +xref: EMAPS:1866628 +is_a: MA:0000337 ! small intestine + +[Term] +id: MA:0000341 +name: oral region +synonym: "mouth" RELATED [] +xref: EMAPS:1626228 +relationship: part_of MA:0000023 ! head +relationship: part_of MA:0000323 ! alimentary system +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000342 +name: gingiva +synonym: "gum" RELATED [] +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0000343 +name: lip +xref: EMAPS:3283928 +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0000344 +name: oral epithelium +xref: EMAPS:2694228 +is_a: MA:0001520 ! gastrointestinal system epithelium +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002794 ! oral mucosa + +[Term] +id: MA:0000345 +name: oral region cartilage/bone +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0000346 +name: salivary gland +xref: EMAPS:1775128 +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0000347 +name: tongue +xref: EMAPS:1718528 +is_a: MA:0000017 ! sensory organ +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002446 ! gustatory system + +[Term] +id: MA:0000348 +name: tooth +xref: EMAPS:3290628 +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0001905 ! jaw +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0000349 +name: incisor +xref: EMAPS:3288928 +is_a: MA:0000348 ! tooth + +[Term] +id: MA:0000350 +name: molar +xref: EMAPS:3289728 +is_a: MA:0000348 ! tooth + +[Term] +id: MA:0000351 +name: oropharynx +xref: EMAPS:2509428 +relationship: part_of MA:0000323 ! alimentary system +relationship: part_of MA:0000432 ! pharynx + +[Term] +id: MA:0000352 +name: esophagus +synonym: "oesophagus" RELATED [] +xref: EMAPS:1683328 +is_a: MA:0000557 ! thoracic cavity organ +is_a: MA:0000589 ! neck organ +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0000353 +name: stomach +xref: EMAPS:1702128 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0000354 +name: bile duct +xref: EMAPS:3517128 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0001273 ! biliary tract + +[Term] +id: MA:0000355 +name: cystic duct +xref: EMAPS:1684128 +relationship: part_of MA:0002659 ! bile duct extrahepatic part + +[Term] +id: MA:0000356 +name: gall bladder +xref: EMAPS:1720228 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0001273 ! biliary tract + +[Term] +id: MA:0000357 +name: hepatic duct +xref: EMAPS:1684328 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0001273 ! biliary tract + +[Term] +id: MA:0000358 +name: liver +xref: EMAPS:1684628 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0000324 ! hepatobiliary system + +[Term] +id: MA:0000359 +name: liver bare area +xref: EMAPS:1794528 +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0000360 +name: liver lobe +xref: EMAPS:1830628 +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0000361 +name: liver left lobe +xref: EMAPS:1830728 +is_a: MA:0000360 ! liver lobe + +[Term] +id: MA:0000362 +name: liver middle lobe +is_a: MA:0000360 ! liver lobe + +[Term] +id: MA:0000363 +name: liver right lobe +xref: EMAPS:1831128 +is_a: MA:0000360 ! liver lobe + +[Term] +id: MA:0000364 +name: liver caudate lobe +synonym: "liver caudate process" RELATED [] +xref: EMAPS:1831328 +is_a: MA:0000363 ! liver right lobe + +[Term] +id: MA:0000365 +name: liver quadrate lobe +xref: EMAPS:1831828 +is_a: MA:0000363 ! liver right lobe + +[Term] +id: MA:0000366 +name: liver parenchyma +synonym: "hepatic parenchyma" RELATED [] +xref: EMAPS:1720328 +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0000367 +name: liver sinusoid +synonym: "hepatic sinusoid" RELATED [] +xref: EMAPS:1736528 +relationship: part_of MA:0002494 ! liver lobule + +[Term] +id: MA:0000368 +name: kidney +xref: EMAPS:1737328 +is_a: MA:0000522 ! abdomen organ +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0000369 +name: kidney calyx +synonym: "renal calyx" RELATED [] +xref: EMAPS:1867628 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000370 +name: kidney capsule +synonym: "renal capsule" RELATED [] +xref: EMAPS:1867928 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000371 +name: kidney collecting duct +synonym: "collecting tubule" RELATED [] +xref: EMAPS:2840728 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000372 +name: kidney cortex +synonym: "renal cortex" RELATED [] +xref: EMAPS:1795228 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000373 +name: kidney medulla +synonym: "renal medulla" RELATED [] +xref: EMAPS:1927928 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000374 +name: kidney pelvis +synonym: "renal pelvis" RELATED [] +xref: EMAPS:1794828 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000375 +name: nephron +xref: EMAPS:3559228 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0000376 +name: renal corpuscle +alt_id: MA:0001656 +synonym: "cortical renal corpuscle" RELATED [] +synonym: "malphighian corpuscle" RELATED [] +xref: EMAPS:3572628 +relationship: part_of MA:0000372 ! kidney cortex +relationship: part_of MA:0000375 ! nephron + +[Term] +id: MA:0000377 +name: kidney tubule +synonym: "renal tubule" RELATED [] +synonym: "uriniferous tubule" RELATED [] +xref: EMAPS:2778228 +relationship: part_of MA:0000368 ! kidney +relationship: part_of MA:0000375 ! nephron + +[Term] +id: MA:0000378 +name: ureter +xref: EMAPS:1795028 +is_a: MA:0000543 ! pelvis organ +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0000379 +name: urethra +xref: EMAPS:3090128 +is_a: MA:0000543 ! pelvis organ +relationship: part_of MA:0002636 ! lower urinary tract + +[Term] +id: MA:0000380 +name: urinary bladder +xref: EMAPS:1832128 +is_a: MA:0000543 ! pelvis organ +relationship: part_of MA:0002636 ! lower urinary tract + +[Term] +id: MA:0000381 +name: female reproductive system +synonym: "female reproductive tract" RELATED [] +xref: EMAPS:1795928 +is_a: MA:0000326 ! reproductive system + +[Term] +id: MA:0000382 +name: clitoris +xref: EMAPS:3081928 +relationship: part_of MA:0000381 ! female reproductive system +relationship: part_of MA:0000395 ! vulva + +[Term] +id: MA:0000383 +name: female reproductive gland +is_a: MA:0001751 ! reproductive gland +relationship: part_of MA:0000544 ! female reproductive gland/organ + +[Term] +id: MA:0000384 +name: ovary +xref: EMAPS:1796228 +is_a: MA:0000544 ! female reproductive gland/organ +is_a: MA:0002420 ! gonad +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000385 +name: oviduct +synonym: "fallopian tube" RELATED [] +synonym: "uterine tube" RELATED [] +xref: EMAPS:1898428 +is_a: MA:0000544 ! female reproductive gland/organ +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000386 +name: placenta +xref: EMAPS:3568928 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000387 +name: os clitoris +xref: EMAPS:3082328 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000388 +name: female germ cell +synonym: "female gamete" RELATED [] +synonym: "oocyte" RELATED [] +synonym: "oogonium" RELATED [] +synonym: "ootid" RELATED [] +synonym: "ovum" RELATED [] +synonym: "unfertilized egg" RELATED [] +xref: EMAPS:1796528 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000389 +name: uterus +xref: EMAPS:2991528 +is_a: MA:0000544 ! female reproductive gland/organ +is_a: MA:0001752 ! reproductive organ +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000390 +name: endometrium +xref: EMAPS:2991728 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0000391 +name: myometrium +synonym: "uterine smooth muscle" RELATED [] +xref: EMAPS:2992328 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0000392 +name: uterine cervix +xref: EMAPS:2992728 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0000393 +name: uterine horn +xref: EMAPS:1898528 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0000394 +name: vagina +xref: EMAPS:1898628 +is_a: MA:0000544 ! female reproductive gland/organ +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000395 +name: vulva +is_a: MA:0000544 ! female reproductive gland/organ +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000396 +name: male reproductive system +synonym: "male reproductive tract" RELATED [] +xref: EMAPS:1796828 +is_a: MA:0000326 ! reproductive system + +[Term] +id: MA:0000397 +name: epididymis +xref: EMAPS:1929028 +is_a: MA:0000545 ! male reproductive gland/organ +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000398 +name: efferent duct +xref: EMAPS:1899328 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000399 +name: male reproductive gland +xref: EMAPS:1928528 +is_a: MA:0001751 ! reproductive gland +relationship: part_of MA:0000545 ! male reproductive gland/organ + +[Term] +id: MA:0000400 +name: ampullary gland +xref: EMAPS:3512328 +is_a: MA:0000399 ! male reproductive gland + +[Term] +id: MA:0000401 +name: bulbourethral gland +xref: EMAPS:1928628 +is_a: MA:0000399 ! male reproductive gland +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0002640 ! male urethra + +[Term] +id: MA:0000402 +name: coagulating gland +synonym: "prostate gland anterior lobe" RELATED [] +xref: EMAPS:3524528 +is_a: MA:0000399 ! male reproductive gland + +[Term] +id: MA:0000403 +name: preputial gland of male +xref: EMAPS:3065928 +is_a: MA:0000399 ! male reproductive gland +is_a: MA:0003044 ! clitoral/preputial gland + +[Term] +id: MA:0000404 +name: prostate gland +xref: EMAPS:1928728 +is_a: MA:0000399 ! male reproductive gland +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0000405 +name: vesicular gland +xref: EMAPS:3592028 +is_a: MA:0000399 ! male reproductive gland + +[Term] +id: MA:0000406 +name: os penis +xref: EMAPS:2976928 +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0000407 +name: prepuce +xref: EMAPS:1898928 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000408 +name: penis +xref: EMAPS:1868228 +is_a: MA:0000545 ! male reproductive gland/organ +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000409 +name: scrotum +xref: EMAPS:1929628 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000410 +name: seminal vesicle +xref: EMAPS:1918028 +is_a: MA:0000545 ! male reproductive gland/organ +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000411 +name: testis +xref: EMAPS:1797228 +is_a: MA:0000545 ! male reproductive gland/organ +is_a: MA:0002420 ! gonad +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000412 +name: seminiferous tubule +xref: EMAPS:1868528 +xref: EMAPS:3147628 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0000413 +name: vas deferens +synonym: "ductus deferens" RELATED [] +xref: EMAPS:1868128 +is_a: MA:0000545 ! male reproductive gland/organ +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000414 +name: larynx +xref: EMAPS:1833328 +is_a: MA:0000589 ! neck organ +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000415 +name: lung +xref: EMAPS:1672828 +is_a: MA:0000557 ! thoracic cavity organ +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000416 +name: alveolar system +xref: EMAPS:3269228 +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0000417 +name: alveolar duct +xref: EMAPS:3269428 +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0000418 +name: alveolar sac +xref: EMAPS:3511928 +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0000419 +name: alveolar atrium +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0000420 +name: lung alveolus +synonym: "pulmonary alveolus" RELATED [] +xref: EMAPS:3268228 +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0000421 +name: interalveolar septum +xref: EMAPS:3543328 +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0000422 +name: bronchiole +xref: EMAPS:3269728 +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0000423 +name: respiratory bronchiole +xref: EMAPS:3572928 +is_a: MA:0000422 ! bronchiole + +[Term] +id: MA:0000424 +name: terminal bronchiole +is_a: MA:0000422 ! bronchiole + +[Term] +id: MA:0000425 +name: left lung +xref: EMAPS:1765328 +is_a: MA:0000415 ! lung + +[Term] +id: MA:0000426 +name: right lung +xref: EMAPS:1766128 +is_a: MA:0000415 ! lung + +[Term] +id: MA:0000427 +name: right lung accessory lobe +synonym: "right lung postcaval lobe" RELATED [] +xref: EMAPS:1798128 +is_a: MA:0001791 ! right lung lobe + +[Term] +id: MA:0000428 +name: right lung caudal lobe +synonym: "right lung inferior lobe" RELATED [] +xref: EMAPS:1798628 +is_a: MA:0001791 ! right lung lobe + +[Term] +id: MA:0000429 +name: right lung cranial lobe +synonym: "right lung superior lobe" RELATED [] +xref: EMAPS:1799128 +is_a: MA:0001791 ! right lung lobe + +[Term] +id: MA:0000430 +name: right lung middle lobe +xref: EMAPS:1799728 +is_a: MA:0001791 ! right lung lobe + +[Term] +id: MA:0000431 +name: paranasal sinus +xref: EMAPS:3566228 +is_a: MA:0000581 ! head organ +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000432 +name: pharynx +xref: EMAPS:1670628 +is_a: MA:0000581 ! head organ +is_a: MA:0000589 ! neck organ +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000433 +name: pleura +xref: EMAPS:1677528 +is_a: MA:0002448 ! cavity lining +relationship: part_of MA:0000055 ! pleural cavity +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000434 +name: respiratory tract +xref: EMAPS:1673728 +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0000435 +name: lower respiratory tract +xref: EMAPS:1673828 +is_a: MA:0000434 ! respiratory tract + +[Term] +id: MA:0000436 +name: bronchus +xref: EMAPS:3268928 +is_a: MA:0000557 ! thoracic cavity organ +relationship: part_of MA:0000435 ! lower respiratory tract + +[Term] +id: MA:0000437 +name: lobar bronchus +xref: EMAPS:3269628 +is_a: MA:0000436 ! bronchus +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0000438 +name: main bronchus +xref: EMAPS:1684928 +is_a: MA:0000436 ! bronchus + +[Term] +id: MA:0000439 +name: segmental bronchus +is_a: MA:0000436 ! bronchus + +[Term] +id: MA:0000440 +name: terminal bronchus +is_a: MA:0000436 ! bronchus + +[Term] +id: MA:0000441 +name: trachea +xref: EMAPS:1685328 +is_a: MA:0000557 ! thoracic cavity organ +is_a: MA:0000589 ! neck organ +relationship: part_of MA:0000435 ! lower respiratory tract + +[Term] +id: MA:0000442 +name: upper respiratory tract +xref: EMAPS:1766928 +is_a: MA:0000434 ! respiratory tract + +[Term] +id: MA:0000443 +name: nasopharynx +xref: EMAPS:1767028 +relationship: part_of MA:0000432 ! pharynx +relationship: part_of MA:0000442 ! upper respiratory tract + +[Term] +id: MA:0000444 +name: left hepatic recess +relationship: part_of MA:0000054 ! peritoneal cavity + +[Term] +id: MA:0000445 +name: omental bursa +xref: EMAPS:1688928 +relationship: part_of MA:0000054 ! peritoneal cavity + +[Term] +id: MA:0000446 +name: omental bursa inferior recess +relationship: part_of MA:0000445 ! omental bursa + +[Term] +id: MA:0000447 +name: omental bursa superior recess +relationship: part_of MA:0000445 ! omental bursa + +[Term] +id: MA:0000448 +name: peritoneal cavity greater sac +xref: EMAPS:1688528 +relationship: part_of MA:0000054 ! peritoneal cavity + +[Term] +id: MA:0000449 +name: peritoneum +xref: EMAPS:1613928 +is_a: MA:0002448 ! cavity lining +relationship: part_of MA:0000054 ! peritoneal cavity + +[Term] +id: MA:0000450 +name: right hepatic recess +relationship: part_of MA:0000054 ! peritoneal cavity + +[Term] +id: MA:0000451 +name: elbow joint +xref: EMAPS:1910228 +is_a: MA:0000614 ! forelimb joint +relationship: part_of MA:0000036 ! elbow + +[Term] +id: MA:0000452 +name: hand joint +xref: EMAPS:3264128 +is_a: MA:0000614 ! forelimb joint +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000453 +name: metacarpo-phalangeal joint +xref: EMAPS:1930228 +is_a: MA:0000452 ! hand joint + +[Term] +id: MA:0000454 +name: hand digit 1 +synonym: "thumb" RELATED [] +xref: EMAPS:1742928 +is_a: MA:0000041 ! hand digit + +[Term] +id: MA:0000455 +name: hand digit 2 +xref: EMAPS:1743228 +is_a: MA:0000041 ! hand digit + +[Term] +id: MA:0000456 +name: hand digit 3 +xref: EMAPS:1743528 +is_a: MA:0000041 ! hand digit + +[Term] +id: MA:0000457 +name: hand digit 4 +xref: EMAPS:1743828 +is_a: MA:0000041 ! hand digit + +[Term] +id: MA:0000458 +name: hand digit 5 +xref: EMAPS:1744128 +is_a: MA:0000041 ! hand digit + +[Term] +id: MA:0000459 +name: shoulder joint +xref: EMAPS:1910528 +is_a: MA:0000614 ! forelimb joint +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000460 +name: wrist joint +is_a: MA:0000614 ! forelimb joint +relationship: part_of MA:0000039 ! wrist + +[Term] +id: MA:0000461 +name: radio-carpal joint +xref: EMAPS:1920528 +is_a: MA:0000460 ! wrist joint + +[Term] +id: MA:0000462 +name: distal radio-ulnar joint +xref: EMAPS:1932628 +is_a: MA:0003145 ! radio-ulnar joint + +[Term] +id: MA:0000463 +name: ankle joint +xref: EMAPS:3512628 +is_a: MA:0000662 ! hindlimb joint +relationship: part_of MA:0000043 ! ankle + +[Term] +id: MA:0000464 +name: foot joint +xref: EMAPS:3294928 +is_a: MA:0000662 ! hindlimb joint +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000465 +name: foot digit 1 +xref: EMAPS:1746028 +is_a: MA:0000048 ! foot digit + +[Term] +id: MA:0000466 +name: foot digit 2 +xref: EMAPS:1746328 +is_a: MA:0000048 ! foot digit + +[Term] +id: MA:0000467 +name: foot digit 3 +xref: EMAPS:1746628 +is_a: MA:0000048 ! foot digit + +[Term] +id: MA:0000468 +name: foot digit 4 +xref: EMAPS:1746928 +is_a: MA:0000048 ! foot digit + +[Term] +id: MA:0000469 +name: foot digit 5 +xref: EMAPS:1747228 +is_a: MA:0000048 ! foot digit + +[Term] +id: MA:0000470 +name: hip joint +xref: EMAPS:1913628 +is_a: MA:0000662 ! hindlimb joint +relationship: part_of MA:0000045 ! hip + +[Term] +id: MA:0000471 +name: knee joint +xref: EMAPS:1913728 +is_a: MA:0000662 ! hindlimb joint +relationship: part_of MA:0000046 ! knee + +[Term] +id: MA:0000472 +name: abdominal fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0000473 +name: subcutaneous adipose tissue +xref: EMAPS:3582928 +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0000474 +name: abdominal aorta +xref: EMAPS:1785628 +relationship: part_of MA:0002571 ! descending aorta + +[Term] +id: MA:0000475 +name: arch of aorta +synonym: "aortic arch" RELATED [] +xref: EMAPS:1731328 +relationship: part_of MA:0002569 ! thoracic aorta + +[Term] +id: MA:0000476 +name: dorsal aorta +xref: EMAPS:1860628 +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0000477 +name: common dorsal aorta +relationship: part_of MA:0000476 ! dorsal aorta + +[Term] +id: MA:0000478 +name: left dorsal aorta +relationship: part_of MA:0000476 ! dorsal aorta + +[Term] +id: MA:0000479 +name: right dorsal aorta +relationship: part_of MA:0000476 ! dorsal aorta + +[Term] +id: MA:0000480 +name: inferior vena cava +xref: EMAPS:1841628 +is_a: MA:0000068 ! vena cava + +[Term] +id: MA:0000481 +name: superior vena cava +xref: EMAPS:1841728 +is_a: MA:0000068 ! vena cava + +[Term] +id: MA:0000482 +name: dorsal mesocardium +xref: EMAPS:1621328 +relationship: part_of MA:0000098 ! heart mesentery + +[Term] +id: MA:0000483 +name: parietal serous pericardium +xref: EMAPS:1903128 +is_a: MA:0002739 ! serous pericardium + +[Term] +id: MA:0000484 +name: visceral serous pericardium +synonym: "epicardium" RELATED [] +xref: EMAPS:1903228 +is_a: MA:0002739 ! serous pericardium + +[Term] +id: MA:0000485 +name: yellow elastic cartilage +is_a: MA:0000107 ! elastic cartilage + +[Term] +id: MA:0000486 +name: white fibrocartilage +is_a: MA:0000108 ! fibrocartilage + +[Term] +id: MA:0000487 +name: articular cartilage +xref: EMAPS:3514928 +is_a: MA:0000109 ! hyaline cartilage + +[Term] +id: MA:0000488 +name: apex of heart +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0000489 +name: outflow tract myocardium +xref: EMAPS:3562328 +is_a: MA:0000164 ! myocardium +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000490 +name: outflow tract endothelium +is_a: MA:0000717 ! cardiovascular system endothelium +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000491 +name: outflow tract pericardium +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000492 +name: outflow tract smooth muscle +relationship: part_of MA:0000100 ! outflow tract + +[Term] +id: MA:0000493 +name: back blood vessel +is_a: MA:0000511 ! trunk blood vessel +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000494 +name: back bone +is_a: MA:0000512 ! trunk bone +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000495 +name: back connective tissue +is_a: MA:0000513 ! trunk connective tissue +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000496 +name: back muscle +xref: EMAPS:3516128 +is_a: MA:0000514 ! trunk muscle +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000497 +name: back nerve +is_a: MA:0000515 ! trunk nerve +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000498 +name: back skin +is_a: MA:0000517 ! trunk skin +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0000499 +name: lower back blood vessel +is_a: MA:0000493 ! back blood vessel +is_a: MA:0000524 ! abdominal segment blood vessel +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000500 +name: lower back bone +is_a: MA:0000494 ! back bone +is_a: MA:0000525 ! abdominal segment bone +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000501 +name: lower back connective tissue +is_a: MA:0000495 ! back connective tissue +is_a: MA:0000526 ! abdominal segment connective tissue +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000502 +name: lower back muscle +is_a: MA:0000496 ! back muscle +is_a: MA:0000527 ! abdominal segment muscle +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000503 +name: lower back nerve +is_a: MA:0000497 ! back nerve +is_a: MA:0000528 ! abdominal segment nerve +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000504 +name: lower back skin +is_a: MA:0000498 ! back skin +is_a: MA:0000530 ! abdominal segment skin +relationship: part_of MA:0000027 ! lower back + +[Term] +id: MA:0000505 +name: upper back blood vessel +is_a: MA:0000493 ! back blood vessel +is_a: MA:0000558 ! thoracic segment blood vessel +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000506 +name: upper back bone +is_a: MA:0000494 ! back bone +is_a: MA:0000559 ! thoracic segment bone +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000507 +name: upper back connective tissue +is_a: MA:0000495 ! back connective tissue +is_a: MA:0000560 ! thoracic segment connective tissue +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000508 +name: upper back muscle +is_a: MA:0000496 ! back muscle +is_a: MA:0000561 ! thoracic segment muscle +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000509 +name: upper back nerve +is_a: MA:0000497 ! back nerve +is_a: MA:0000562 ! thoracic segment nerve +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000510 +name: upper back skin +is_a: MA:0000498 ! back skin +is_a: MA:0000564 ! thorax skin +relationship: part_of MA:0000028 ! upper back + +[Term] +id: MA:0000511 +name: trunk blood vessel +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000512 +name: trunk bone +is_a: MA:0001459 ! bone +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000513 +name: trunk connective tissue +is_a: MA:0000011 ! connective tissue +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000514 +name: trunk muscle +xref: EMAPS:3588828 +is_a: MA:0000165 ! set of skeletal muscles +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000515 +name: trunk nerve +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000516 +name: trunk organ +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000517 +name: trunk skin +is_a: MA:0000151 ! skin +relationship: part_of MA:0000004 ! trunk + +[Term] +id: MA:0000518 +name: abdomen blood vessel +is_a: MA:0000524 ! abdominal segment blood vessel +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000519 +name: abdomen connective tissue +is_a: MA:0000526 ! abdominal segment connective tissue +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000520 +name: abdomen muscle +xref: EMAPS:3510328 +is_a: MA:0000527 ! abdominal segment muscle +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000521 +name: abdomen nerve +is_a: MA:0000528 ! abdominal segment nerve +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000522 +name: abdomen organ +is_a: MA:0000529 ! abdominal segment organ +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000523 +name: abdomen skin +is_a: MA:0000530 ! abdominal segment skin +relationship: part_of MA:0000029 ! abdomen + +[Term] +id: MA:0000524 +name: abdominal segment blood vessel +is_a: MA:0000511 ! trunk blood vessel +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000525 +name: abdominal segment bone +is_a: MA:0000512 ! trunk bone +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000526 +name: abdominal segment connective tissue +is_a: MA:0000513 ! trunk connective tissue +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000527 +name: abdominal segment muscle +is_a: MA:0000514 ! trunk muscle +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000528 +name: abdominal segment nerve +is_a: MA:0000515 ! trunk nerve +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000529 +name: abdominal segment organ +is_a: MA:0000516 ! trunk organ +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000530 +name: abdominal segment skin +is_a: MA:0000517 ! trunk skin +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0000531 +name: pelvis blood vessel +is_a: MA:0000524 ! abdominal segment blood vessel +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000532 +name: pelvis bone +is_a: MA:0000525 ! abdominal segment bone +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000533 +name: pelvis connective tissue +is_a: MA:0000526 ! abdominal segment connective tissue +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000534 +name: pelvis muscle +xref: EMAPS:1818428 +is_a: MA:0000527 ! abdominal segment muscle +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000535 +name: gluteal muscle +xref: EMAPS:1818628 +is_a: MA:0000534 ! pelvis muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0000536 +name: iliac region muscle +is_a: MA:0000534 ! pelvis muscle + +[Term] +id: MA:0000537 +name: pelvic girdle muscle +xref: EMAPS:1818528 +is_a: MA:0000534 ! pelvis muscle + +[Term] +id: MA:0000538 +name: perineal muscle +is_a: MA:0000534 ! pelvis muscle + +[Term] +id: MA:0000539 +name: urogenital muscle +is_a: MA:0000534 ! pelvis muscle + +[Term] +id: MA:0000540 +name: female urogenital muscle +is_a: MA:0000539 ! urogenital muscle + +[Term] +id: MA:0000541 +name: male urogenital muscle +is_a: MA:0000539 ! urogenital muscle + +[Term] +id: MA:0000542 +name: pelvis nerve +is_a: MA:0000528 ! abdominal segment nerve +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000543 +name: pelvis organ +is_a: MA:0000529 ! abdominal segment organ +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000544 +name: female reproductive gland/organ +xref: EMAPS:2854028 +is_a: MA:0000543 ! pelvis organ +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0000545 +name: male reproductive gland/organ +is_a: MA:0000543 ! pelvis organ +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0000546 +name: pelvis skin +is_a: MA:0000530 ! abdominal segment skin +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0000547 +name: chest bone +xref: EMAPS:1802528 +is_a: MA:0000559 ! thoracic segment bone +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000548 +name: chest muscle +xref: EMAPS:1774728 +xref: EMAPS:1774828 +is_a: MA:0000561 ! thoracic segment muscle +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000549 +name: chest blood vessel +is_a: MA:0000558 ! thoracic segment blood vessel +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000550 +name: chest connective tissue +is_a: MA:0000560 ! thoracic segment connective tissue +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000551 +name: chest nerve +is_a: MA:0000562 ! thoracic segment nerve +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000552 +name: chest organ +is_a: MA:0000563 ! thoracic segment organ +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000553 +name: chest skin +is_a: MA:0000564 ! thorax skin +relationship: part_of MA:0000031 ! chest + +[Term] +id: MA:0000554 +name: thoracic cavity blood vessel +is_a: MA:0000558 ! thoracic segment blood vessel +relationship: part_of MA:0000032 ! thoracic cavity + +[Term] +id: MA:0000555 +name: thoracic cavity connective tissue +is_a: MA:0000560 ! thoracic segment connective tissue +relationship: part_of MA:0000032 ! thoracic cavity + +[Term] +id: MA:0000556 +name: thoracic cavity nerve +is_a: MA:0000562 ! thoracic segment nerve +relationship: part_of MA:0000032 ! thoracic cavity + +[Term] +id: MA:0000557 +name: thoracic cavity organ +is_a: MA:0000563 ! thoracic segment organ +relationship: part_of MA:0000032 ! thoracic cavity + +[Term] +id: MA:0000558 +name: thoracic segment blood vessel +synonym: "upper body blood vessel" RELATED [] +is_a: MA:0000511 ! trunk blood vessel +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000559 +name: thoracic segment bone +synonym: "upper body bone" RELATED [] +is_a: MA:0000512 ! trunk bone +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000560 +name: thoracic segment connective tissue +synonym: "upper body connective tissue" RELATED [] +is_a: MA:0000513 ! trunk connective tissue +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000561 +name: thoracic segment muscle +synonym: "upper body muscle" RELATED [] +is_a: MA:0000514 ! trunk muscle +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000562 +name: thoracic segment nerve +synonym: "upper body nerve" RELATED [] +is_a: MA:0000515 ! trunk nerve +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000563 +name: thoracic segment organ +synonym: "upper body organ" RELATED [] +is_a: MA:0000516 ! trunk organ +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000564 +name: thorax skin +synonym: "upper body skin" RELATED [] +is_a: MA:0000517 ! trunk skin +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0000565 +name: mesothelium +xref: EMAPS:3285628 +is_a: MA:0000005 ! body cavity or lining + +[Term] +id: MA:0000566 +name: parietal mesothelium +is_a: MA:0000565 ! mesothelium + +[Term] +id: MA:0000567 +name: visceral mesothelium +is_a: MA:0000565 ! mesothelium + +[Term] +id: MA:0000568 +name: head or neck blood vessel +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000569 +name: head or neck bone +is_a: MA:0001459 ! bone +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000570 +name: head or neck connective tissue +is_a: MA:0000011 ! connective tissue +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000571 +name: head or neck muscle +is_a: MA:0000165 ! set of skeletal muscles +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000572 +name: head or neck nerve or ganglion +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000573 +name: head or neck organ +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000574 +name: head or neck skin +is_a: MA:0000151 ! skin +relationship: part_of MA:0000006 ! head and neck + +[Term] +id: MA:0000575 +name: head blood vessel +is_a: MA:0000568 ! head or neck blood vessel +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000576 +name: head bone +xref: EMAPS:3599628 +is_a: MA:0000569 ! head or neck bone +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000577 +name: head connective tissue +xref: EMAPS:1609828 +is_a: MA:0000570 ! head or neck connective tissue +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000578 +name: head muscle +xref: EMAPS:1817228 +is_a: MA:0000571 ! head or neck muscle +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000579 +name: cranial/facial muscle +xref: EMAPS:3526528 +is_a: MA:0000578 ! head muscle + +[Term] +id: MA:0000580 +name: head nerve/ganglion +is_a: MA:0000572 ! head or neck nerve or ganglion +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000581 +name: head organ +is_a: MA:0000573 ! head or neck organ +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000582 +name: head skin +is_a: MA:0000574 ! head or neck skin +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0000583 +name: neck blood vessel +is_a: MA:0000568 ! head or neck blood vessel +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000584 +name: neck bone +is_a: MA:0000569 ! head or neck bone +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000585 +name: neck connective tissue +is_a: MA:0000570 ! head or neck connective tissue +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000586 +name: neck cartilage +is_a: MA:0000585 ! neck connective tissue + +[Term] +id: MA:0000587 +name: neck muscle +is_a: MA:0000571 ! head or neck muscle +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000588 +name: neck nerve +is_a: MA:0000572 ! head or neck nerve or ganglion +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000589 +name: neck organ +is_a: MA:0000573 ! head or neck organ +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000590 +name: neck skin +is_a: MA:0000574 ! head or neck skin +relationship: part_of MA:0000024 ! neck + +[Term] +id: MA:0000591 +name: arm blood vessel +is_a: MA:0000611 ! forelimb blood vessel +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000592 +name: arm bone +is_a: MA:0000612 ! forelimb bone +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000593 +name: arm connective tissue +is_a: MA:0000613 ! forelimb connective tissue +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000594 +name: arm muscle +is_a: MA:0000615 ! forelimb muscle +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000595 +name: arm nerve +is_a: MA:0000616 ! forelimb nerve +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000596 +name: arm skin +is_a: MA:0000617 ! forelimb skin +relationship: part_of MA:0000033 ! arm + +[Term] +id: MA:0000597 +name: lower arm blood vessel +is_a: MA:0000591 ! arm blood vessel +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000598 +name: lower arm bone +xref: EMAPS:3534728 +is_a: MA:0000592 ! arm bone +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000599 +name: lower arm connective tissue +is_a: MA:0000593 ! arm connective tissue +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000600 +name: lower arm muscle +is_a: MA:0000594 ! arm muscle +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000601 +name: lower arm nerve +is_a: MA:0000595 ! arm nerve +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000602 +name: lower arm skin +is_a: MA:0000596 ! arm skin +relationship: part_of MA:0000034 ! lower arm + +[Term] +id: MA:0000603 +name: upper arm blood vessel +is_a: MA:0000591 ! arm blood vessel +relationship: part_of MA:0000035 ! upper arm + +[Term] +id: MA:0000604 +name: upper arm bone +xref: EMAPS:3589228 +is_a: MA:0000592 ! arm bone +relationship: part_of MA:0000035 ! upper arm + +[Term] +id: MA:0000605 +name: upper arm connective tissue +xref: EMAPS:1742628 +is_a: MA:0000593 ! arm connective tissue +relationship: part_of MA:0000035 ! upper arm + +[Term] +id: MA:0000606 +name: upper arm muscle +xref: EMAPS:1910728 +is_a: MA:0000594 ! arm muscle +relationship: part_of MA:0000035 ! upper arm + +[Term] +id: MA:0000607 +name: upper arm nerve +is_a: MA:0000595 ! arm nerve + +[Term] +id: MA:0000608 +name: upper arm skin +xref: EMAPS:1806228 +is_a: MA:0000596 ! arm skin +relationship: part_of MA:0000035 ! upper arm + +[Term] +id: MA:0000609 +name: elbow connective tissue +xref: EMAPS:1741628 +is_a: MA:0000593 ! arm connective tissue +relationship: part_of MA:0000036 ! elbow + +[Term] +id: MA:0000610 +name: elbow skin +xref: EMAPS:1805128 +is_a: MA:0000596 ! arm skin +relationship: part_of MA:0000036 ! elbow + +[Term] +id: MA:0000611 +name: forelimb blood vessel +is_a: MA:0000687 ! limb blood vessel +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000612 +name: forelimb bone +xref: EMAPS:3262328 +xref: EMAPS:3593328 +is_a: MA:0000688 ! limb bone +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000613 +name: forelimb connective tissue +xref: EMAPS:3262828 +is_a: MA:0000689 ! limb connective tissue +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000614 +name: forelimb joint +xref: EMAPS:1920428 +is_a: MA:0000691 ! limb joint +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000615 +name: forelimb muscle +xref: EMAPS:3262428 +is_a: MA:0000692 ! limb muscle +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000616 +name: forelimb nerve +is_a: MA:0000693 ! limb nerve +relationship: part_of MA:0000025 ! forelimb + +[Term] +id: MA:0000617 +name: forelimb skin +xref: EMAPS:3261228 +relationship: part_of MA:0000025 ! forelimb +relationship: part_of MA:0000694 ! limb skin + +[Term] +id: MA:0000618 +name: hand blood vessel +is_a: MA:0000611 ! forelimb blood vessel +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000619 +name: hand bone +xref: EMAPS:3264328 +xref: EMAPS:3539128 +is_a: MA:0000612 ! forelimb bone +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000620 +name: hand connective tissue +xref: EMAPS:1745728 +xref: EMAPS:3539228 +is_a: MA:0000613 ! forelimb connective tissue +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000621 +name: hand digit blood vessel +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000622 +name: hand digit bone +is_a: MA:0000619 ! hand bone +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000623 +name: hand digit connective tissue +xref: EMAPS:3264528 +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000624 +name: hand digit muscle +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000625 +name: hand digit nerve +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000626 +name: hand digit skin +xref: EMAPS:3264828 +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000627 +name: hand interdigit region +xref: EMAPS:3265128 +relationship: part_of MA:0000041 ! hand digit + +[Term] +id: MA:0000628 +name: hand muscle +is_a: MA:0000615 ! forelimb muscle +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000629 +name: hand nerve +is_a: MA:0000616 ! forelimb nerve +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000630 +name: hand skin +xref: EMAPS:1848628 +is_a: MA:0000617 ! forelimb skin +relationship: part_of MA:0000037 ! hand + +[Term] +id: MA:0000631 +name: shoulder bone +is_a: MA:0000612 ! forelimb bone +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000632 +name: shoulder connective tissue +xref: EMAPS:1742328 +is_a: MA:0000613 ! forelimb connective tissue +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000633 +name: shoulder muscle +is_a: MA:0000615 ! forelimb muscle +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000634 +name: shoulder nerve +is_a: MA:0000616 ! forelimb nerve +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000635 +name: shoulder skin +xref: EMAPS:1805928 +is_a: MA:0000617 ! forelimb skin +relationship: part_of MA:0000038 ! shoulder + +[Term] +id: MA:0000636 +name: wrist connective tissue +is_a: MA:0000613 ! forelimb connective tissue +relationship: part_of MA:0000039 ! wrist + +[Term] +id: MA:0000637 +name: wrist nerve +is_a: MA:0000616 ! forelimb nerve +relationship: part_of MA:0000039 ! wrist + +[Term] +id: MA:0000638 +name: wrist skin +is_a: MA:0000617 ! forelimb skin +relationship: part_of MA:0000039 ! wrist + +[Term] +id: MA:0000639 +name: ankle connective tissue +is_a: MA:0000661 ! hindlimb connective tissue +relationship: part_of MA:0000043 ! ankle + +[Term] +id: MA:0000640 +name: ankle nerve +is_a: MA:0000664 ! hindlimb nerve +relationship: part_of MA:0000043 ! ankle + +[Term] +id: MA:0000641 +name: ankle skin +is_a: MA:0000665 ! hindlimb skin +relationship: part_of MA:0000043 ! ankle + +[Term] +id: MA:0000642 +name: foot blood vessel +is_a: MA:0000659 ! hindlimb blood vessel +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000643 +name: foot bone +xref: EMAPS:3535428 +is_a: MA:0000660 ! hindlimb bone +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000644 +name: foot connective tissue +xref: EMAPS:1748828 +is_a: MA:0000661 ! hindlimb connective tissue +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000645 +name: foot digit blood vessel +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000646 +name: foot digit bone +is_a: MA:0000643 ! foot bone +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000647 +name: foot digit connective tissue +xref: EMAPS:3294728 +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000648 +name: foot digit muscle +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000649 +name: foot digit nerve +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000650 +name: foot digit skin +xref: EMAPS:3294228 +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000651 +name: foot interdigit region +xref: EMAPS:3294528 +relationship: part_of MA:0000048 ! foot digit + +[Term] +id: MA:0000652 +name: foot muscle +is_a: MA:0000663 ! hindlimb muscle +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000653 +name: foot nerve +is_a: MA:0000664 ! hindlimb nerve +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000654 +name: foot skin +xref: EMAPS:1850428 +is_a: MA:0000665 ! hindlimb skin +relationship: part_of MA:0000044 ! foot + +[Term] +id: MA:0000655 +name: hip bone +is_a: MA:0000660 ! hindlimb bone +relationship: part_of MA:0000045 ! hip + +[Term] +id: MA:0000656 +name: hip connective tissue +xref: EMAPS:1749228 +is_a: MA:0000661 ! hindlimb connective tissue +relationship: part_of MA:0000045 ! hip + +[Term] +id: MA:0000657 +name: hip muscle +is_a: MA:0000663 ! hindlimb muscle +relationship: part_of MA:0000045 ! hip + +[Term] +id: MA:0000658 +name: hip skin +xref: EMAPS:1814828 +is_a: MA:0000665 ! hindlimb skin +relationship: part_of MA:0000045 ! hip + +[Term] +id: MA:0000659 +name: hindlimb blood vessel +is_a: MA:0000687 ! limb blood vessel +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000660 +name: hindlimb bone +xref: EMAPS:3263328 +xref: EMAPS:3593428 +is_a: MA:0000688 ! limb bone +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000661 +name: hindlimb connective tissue +xref: EMAPS:3263728 +is_a: MA:0000689 ! limb connective tissue +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000662 +name: hindlimb joint +xref: EMAPS:3263528 +is_a: MA:0000691 ! limb joint +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000663 +name: hindlimb muscle +xref: EMAPS:3263428 +is_a: MA:0000692 ! limb muscle +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000664 +name: hindlimb nerve +is_a: MA:0000693 ! limb nerve +relationship: part_of MA:0000026 ! hindlimb + +[Term] +id: MA:0000665 +name: hindlimb skin +xref: EMAPS:3262028 +relationship: part_of MA:0000026 ! hindlimb +relationship: part_of MA:0000694 ! limb skin + +[Term] +id: MA:0000666 +name: knee bone +is_a: MA:0000670 ! leg bone +relationship: part_of MA:0000046 ! knee + +[Term] +id: MA:0000667 +name: knee connective tissue +xref: EMAPS:1749528 +is_a: MA:0000671 ! leg connective tissue +relationship: part_of MA:0000046 ! knee + +[Term] +id: MA:0000668 +name: knee skin +xref: EMAPS:1815128 +is_a: MA:0000665 ! hindlimb skin +relationship: part_of MA:0000046 ! knee + +[Term] +id: MA:0000669 +name: leg blood vessel +is_a: MA:0000659 ! hindlimb blood vessel +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000670 +name: leg bone +is_a: MA:0000660 ! hindlimb bone +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000671 +name: leg connective tissue +is_a: MA:0000661 ! hindlimb connective tissue +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000672 +name: leg muscle +is_a: MA:0000663 ! hindlimb muscle +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000673 +name: leg nerve +is_a: MA:0000664 ! hindlimb nerve +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000674 +name: leg skin +is_a: MA:0000665 ! hindlimb skin +relationship: part_of MA:0000047 ! leg + +[Term] +id: MA:0000675 +name: lower leg blood vessel +is_a: MA:0000669 ! leg blood vessel +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000676 +name: lower leg bone +xref: EMAPS:3551928 +is_a: MA:0000670 ! leg bone +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000677 +name: lower leg connective tissue +xref: EMAPS:1749828 +is_a: MA:0000671 ! leg connective tissue +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000678 +name: lower leg muscle +xref: EMAPS:1931828 +is_a: MA:0000672 ! leg muscle +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000679 +name: lower leg nerve +is_a: MA:0000673 ! leg nerve +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000680 +name: lower leg skin +xref: EMAPS:1815628 +is_a: MA:0000674 ! leg skin +relationship: part_of MA:0000051 ! lower leg + +[Term] +id: MA:0000681 +name: upper leg blood vessel +is_a: MA:0000669 ! leg blood vessel +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000682 +name: upper leg bone +xref: EMAPS:3589328 +is_a: MA:0000670 ! leg bone +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000683 +name: upper leg connective tissue +xref: EMAPS:1750128 +is_a: MA:0000671 ! leg connective tissue +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000684 +name: upper leg muscle +xref: EMAPS:1914428 +is_a: MA:0000672 ! leg muscle +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000685 +name: upper leg nerve +is_a: MA:0000673 ! leg nerve +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000686 +name: upper leg skin +xref: EMAPS:1815928 +is_a: MA:0000674 ! leg skin +relationship: part_of MA:0000052 ! upper leg + +[Term] +id: MA:0000687 +name: limb blood vessel +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000688 +name: limb bone +alt_id: MA:0000294 +xref: EMAPS:3270528 +xref: EMAPS:3549428 +is_a: MA:0001459 ! bone +relationship: part_of MA:0000007 ! limb +relationship: part_of MA:0000290 ! appendicular skeleton + +[Term] +id: MA:0000689 +name: limb connective tissue +xref: EMAPS:3270528 +is_a: MA:0000011 ! connective tissue +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000690 +name: limb digit +xref: EMAPS:3272528 +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000691 +name: limb joint +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000692 +name: limb muscle +xref: EMAPS:3270028 +is_a: MA:0000165 ! set of skeletal muscles +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000693 +name: limb nerve +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000694 +name: limb skin +xref: EMAPS:3272628 +is_a: MA:0000151 ! skin +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0000695 +name: tail blood vessel +xref: EMAPS:3584828 +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0000696 +name: tail bone +xref: EMAPS:1804228 +is_a: MA:0001459 ! bone +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0000697 +name: tail connective tissue +xref: EMAPS:1674928 +is_a: MA:0000011 ! connective tissue +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0000698 +name: tail intervertebral disc +xref: EMAPS:1959228 +is_a: MA:0000697 ! tail connective tissue + +[Term] +id: MA:0000699 +name: tail muscle +is_a: MA:0000165 ! set of skeletal muscles +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0000700 +name: tail skin +is_a: MA:0000151 ! skin +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0000701 +name: aorta endothelium +xref: EMAPS:3513428 +is_a: MA:0000703 ! arterial system endothelium +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0000702 +name: aorta smooth muscle +xref: EMAPS:3513528 +is_a: MA:0000704 ! arterial system smooth muscle +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0000703 +name: arterial system endothelium +xref: EMAPS:3514528 +is_a: MA:0000709 ! blood vessel endothelium +relationship: part_of MA:0002719 ! arterial system + +[Term] +id: MA:0000704 +name: arterial system smooth muscle +is_a: MA:0000710 ! blood vessel smooth muscle +relationship: part_of MA:0002719 ! arterial system + +[Term] +id: MA:0000705 +name: arteriole endothelium +is_a: MA:0000703 ! arterial system endothelium +relationship: part_of MA:0000063 ! arteriole + +[Term] +id: MA:0000706 +name: arteriole smooth muscle +is_a: MA:0000704 ! arterial system smooth muscle +relationship: part_of MA:0000063 ! arteriole + +[Term] +id: MA:0000707 +name: artery endothelium +xref: EMAPS:3514828 +is_a: MA:0000703 ! arterial system endothelium +relationship: part_of MA:0000064 ! artery + +[Term] +id: MA:0000708 +name: artery smooth muscle +is_a: MA:0000704 ! arterial system smooth muscle +relationship: part_of MA:0000064 ! artery + +[Term] +id: MA:0000709 +name: blood vessel endothelium +xref: EMAPS:3517628 +is_a: MA:0000717 ! cardiovascular system endothelium +relationship: part_of MA:0000060 ! blood vessel + +[Term] +id: MA:0000710 +name: blood vessel smooth muscle +xref: EMAPS:3517728 +relationship: part_of MA:0000060 ! blood vessel + +[Term] +id: MA:0000711 +name: capillary endothelium +is_a: MA:0000709 ! blood vessel endothelium +relationship: part_of MA:0000065 ! capillary + +[Term] +id: MA:0000712 +name: vein endothelium +is_a: MA:0000714 ! venous system endothelium +relationship: part_of MA:0000067 ! vein + +[Term] +id: MA:0000713 +name: vena cava endothelium +is_a: MA:0000714 ! venous system endothelium +relationship: part_of MA:0000068 ! vena cava + +[Term] +id: MA:0000714 +name: venous system endothelium +xref: EMAPS:3590728 +is_a: MA:0000709 ! blood vessel endothelium +relationship: part_of MA:0002720 ! venous system + +[Term] +id: MA:0000715 +name: venous system smooth muscle +relationship: part_of MA:0000710 ! blood vessel smooth muscle +relationship: part_of MA:0002720 ! venous system + +[Term] +id: MA:0000716 +name: venule endothelium +is_a: MA:0000714 ! venous system endothelium +relationship: part_of MA:0000071 ! venule + +[Term] +id: MA:0000717 +name: cardiovascular system endothelium +xref: EMAPS:3520128 +relationship: part_of MA:0000010 ! cardiovascular system + +[Term] +id: MA:0000718 +name: left adrenal gland +is_a: MA:0000116 ! adrenal gland + +[Term] +id: MA:0000719 +name: right adrenal gland +is_a: MA:0000116 ! adrenal gland + +[Term] +id: MA:0000720 +name: neuroendocrine gland +is_a: MA:0002563 ! endocrine gland + +[Term] +id: MA:0000721 +name: pancreas lobe +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0000722 +name: pancreas left lobe +is_a: MA:0000721 ! pancreas lobe + +[Term] +id: MA:0000723 +name: pancreas right lobe +is_a: MA:0000721 ! pancreas lobe + +[Term] +id: MA:0000724 +name: pancreas parenchyma +xref: EMAPS:3292528 +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0000725 +name: foramen caecum +xref: EMAPS:1706928 +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000726 +name: thyroid gland follicle +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000727 +name: thyroid gland isthmus +xref: EMAPS:1819528 +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000728 +name: thyroid gland left lobe +xref: EMAPS:1819728 +is_a: MA:0000131 ! thyroid gland lobe + +[Term] +id: MA:0000729 +name: thyroid gland right lobe +xref: EMAPS:1819828 +is_a: MA:0000131 ! thyroid gland lobe + +[Term] +id: MA:0000730 +name: thyroid gland parenchyma +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0000731 +name: peyer's patch epithelium +relationship: part_of MA:0000137 ! peyer's patch + +[Term] +id: MA:0000732 +name: peyer's patch follicle +relationship: part_of MA:0000137 ! peyer's patch + +[Term] +id: MA:0000733 +name: peyer's patch dome +relationship: part_of MA:0000732 ! peyer's patch follicle + +[Term] +id: MA:0000734 +name: peyer's patch germinal center +xref: EMAPS:3568428 +relationship: part_of MA:0000137 ! peyer's patch + +[Term] +id: MA:0000735 +name: axillary lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0000736 +name: cervical lymph node +is_a: MA:0000139 ! lymph node +is_a: MA:0000589 ! neck organ + +[Term] +id: MA:0000737 +name: inguinal lymph node +xref: EMAPS:3543128 +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0000738 +name: popliteal lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0000739 +name: lymph node capsule +xref: EMAPS:3552428 +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000740 +name: lymph node cortex +xref: EMAPS:3552528 +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000741 +name: lymph node endothelium +xref: EMAPS:3552628 +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000742 +name: lymph node follicle +xref: EMAPS:3552728 +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000743 +name: lymph node primary follicle +xref: EMAPS:3553028 +is_a: MA:0000742 ! lymph node follicle + +[Term] +id: MA:0000744 +name: lymph node secondary follicle +synonym: "lymph node germinal center" RELATED [] +xref: EMAPS:3553128 +is_a: MA:0000742 ! lymph node follicle + +[Term] +id: MA:0000745 +name: lymph node medulla +xref: EMAPS:3552928 +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000746 +name: lymph node trabeculum +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0000747 +name: lymph organ +relationship: part_of MA:0002435 ! lymphoid system + +[Term] +id: MA:0000748 +name: afferent lymphatic vessel +is_a: MA:0000138 ! lymphatic vessel + +[Term] +id: MA:0000749 +name: efferent lymphatic vessel +is_a: MA:0000138 ! lymphatic vessel + +[Term] +id: MA:0000750 +name: lymphatic vessel endothelium +xref: EMAPS:3553328 +relationship: part_of MA:0000138 ! lymphatic vessel + +[Term] +id: MA:0000751 +name: lymphatic vessel smooth muscle +relationship: part_of MA:0000138 ! lymphatic vessel + +[Term] +id: MA:0000752 +name: oropharyngeal lymphoid tissue +synonym: "waldeyer's ring" RELATED [] +is_a: MA:0000140 ! mucosa associated lymphoid tissue + +[Term] +id: MA:0000753 +name: spleen capsule +xref: EMAPS:3580228 +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0000754 +name: spleen marginal sinus +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0000755 +name: spleen marginal zone +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0000756 +name: spleen red pulp +xref: EMAPS:3580628 +relationship: part_of MA:0002487 ! spleen pulp + +[Term] +id: MA:0000757 +name: spleen smooth muscle +xref: EMAPS:3580728 +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0000758 +name: spleen trabeculum +xref: EMAPS:3580828 +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0000759 +name: spleen trabecular artery +relationship: part_of MA:0000758 ! spleen trabeculum + +[Term] +id: MA:0000760 +name: spleen trabecular vein +relationship: part_of MA:0000758 ! spleen trabeculum + +[Term] +id: MA:0000761 +name: spleen venous sinus +relationship: part_of MA:0000756 ! spleen red pulp + +[Term] +id: MA:0000762 +name: spleen white pulp +xref: EMAPS:3580928 +relationship: part_of MA:0002487 ! spleen pulp + +[Term] +id: MA:0000763 +name: spleen central arteriole +relationship: part_of MA:0000762 ! spleen white pulp + +[Term] +id: MA:0000764 +name: spleen germinal center +xref: EMAPS:3580328 +relationship: part_of MA:0000762 ! spleen white pulp + +[Term] +id: MA:0000765 +name: spleen periarteriolar lymphatic sheath +synonym: "PALS" RELATED [] +relationship: part_of MA:0000762 ! spleen white pulp + +[Term] +id: MA:0000766 +name: thymus capsule +xref: EMAPS:1930628 +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0000767 +name: thymus cortex +xref: EMAPS:3586328 +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0000768 +name: thymus epithelium +xref: EMAPS:3586428 +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0000769 +name: thymus subcapsular epithelium +is_a: MA:0000768 ! thymus epithelium + +[Term] +id: MA:0000770 +name: thymus lobule +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0000771 +name: thymus medulla +xref: EMAPS:1930528 +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0000772 +name: hassall's corpuscle +xref: EMAPS:3539528 +relationship: part_of MA:0000771 ! thymus medulla + +[Term] +id: MA:0000773 +name: lingual tonsillar tissue +is_a: MA:0000143 ! tonsil + +[Term] +id: MA:0000774 +name: nasopharyngeal tonsil +is_a: MA:0000143 ! tonsil + +[Term] +id: MA:0000775 +name: palatine tonsil +xref: EMAPS:3564428 +is_a: MA:0000143 ! tonsil + +[Term] +id: MA:0000776 +name: tonsil capsule +relationship: part_of MA:0000143 ! tonsil + +[Term] +id: MA:0000777 +name: tonsil crypt +relationship: part_of MA:0000143 ! tonsil + +[Term] +id: MA:0000778 +name: arrector pili smooth muscle +xref: EMAPS:2677528 +is_a: MA:0002710 ! skin muscle +relationship: part_of MA:0000160 ! coat hair follicle + +[Term] +id: MA:0000779 +name: hair inner root sheath +xref: EMAPS:3279228 +relationship: part_of MA:0000162 ! hair root sheath + +[Term] +id: MA:0000780 +name: hair outer root sheath +xref: EMAPS:3279328 +relationship: part_of MA:0000162 ! hair root sheath + +[Term] +id: MA:0000781 +name: hair root sheath matrix +xref: EMAPS:3539028 +relationship: part_of MA:0000162 ! hair root sheath + +[Term] +id: MA:0000782 +name: vibrissa hair +relationship: part_of MA:0000163 ! vibrissa + +[Term] +id: MA:0000783 +name: vibrissa hair bulb +xref: EMAPS:2671628 +relationship: part_of MA:0000163 ! vibrissa + +[Term] +id: MA:0000784 +name: vibrissa root sheath +xref: EMAPS:2672428 +relationship: part_of MA:0000783 ! vibrissa hair bulb + +[Term] +id: MA:0000785 +name: vibrissa inner root sheath +relationship: part_of MA:0000784 ! vibrissa root sheath + +[Term] +id: MA:0000786 +name: vibrissa outer root sheath +relationship: part_of MA:0000784 ! vibrissa root sheath + +[Term] +id: MA:0000787 +name: abdominal mammary gland +is_a: MA:0000145 ! mammary gland +is_a: MA:0000522 ! abdomen organ + +[Term] +id: MA:0000788 +name: areola +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000789 +name: cervical mammary gland +is_a: MA:0000145 ! mammary gland +is_a: MA:0000589 ! neck organ + +[Term] +id: MA:0000790 +name: inguinal mammary gland +is_a: MA:0000145 ! mammary gland + +[Term] +id: MA:0000791 +name: mammary gland duct +synonym: "lactiferous duct" RELATED [] +xref: EMAPS:3553828 +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000792 +name: mammary gland epithelium +xref: EMAPS:1776028 +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000793 +name: mammary gland lobule +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000794 +name: mammary gland sebaceous gland +is_a: MA:0002565 ! sebaceous gland +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000795 +name: mammary gland smooth muscle +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000796 +name: nipple +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0000797 +name: thoracic mammary gland +is_a: MA:0000145 ! mammary gland +is_a: MA:0000552 ! chest organ + +[Term] +id: MA:0000798 +name: dermis adipose tissue +relationship: part_of MA:0000152 ! dermis + +[Term] +id: MA:0000799 +name: dermis connective tissue +relationship: part_of MA:0000152 ! dermis + +[Term] +id: MA:0000800 +name: dermis papillary layer +xref: EMAPS:3528228 +relationship: part_of MA:0000152 ! dermis + +[Term] +id: MA:0000801 +name: dermis reticular layer +xref: EMAPS:3528328 +relationship: part_of MA:0000152 ! dermis + +[Term] +id: MA:0000802 +name: superficial dermis +relationship: part_of MA:0000152 ! dermis + +[Term] +id: MA:0000803 +name: epidermis stratum basale +synonym: "epidermis basal layer" RELATED [] +synonym: "epidermis stratum germinativum" RELATED [] +xref: EMAPS:3277928 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000804 +name: epidermis stratum corneum +xref: EMAPS:3278728 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000805 +name: epidermis stratum granulosum +synonym: "epidermis granular layer" RELATED [] +xref: EMAPS:3278628 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000806 +name: epidermis stratum lucidum +xref: EMAPS:3531428 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000807 +name: epidermis stratum spinosum +synonym: "epidermis prickle cell layer" RELATED [] +xref: EMAPS:3278528 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000808 +name: epidermis suprabasal layer +xref: EMAPS:3531528 +relationship: part_of MA:0000153 ! epidermis + +[Term] +id: MA:0000809 +name: brain ependyma +xref: EMAPS:3518328 +relationship: part_of MA:0000168 ! brain +relationship: part_of MA:0000818 ! brain ventricle + +[Term] +id: MA:0000810 +name: brain grey matter +xref: EMAPS:3518428 +is_a: MA:0001112 ! grey matter +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000811 +name: brain nucleus +xref: EMAPS:3518528 +relationship: part_of MA:0000810 ! brain grey matter + +[Term] +id: MA:0000812 +name: brain marginal zone +xref: EMAPS:3268028 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000813 +name: brain meninges +xref: EMAPS:3266228 +is_a: MA:0001113 ! meninges +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000814 +name: brain arachnoid matter +xref: EMAPS:3266128 +is_a: MA:0001114 ! arachnoid mater +relationship: part_of MA:0000813 ! brain meninges + +[Term] +id: MA:0000815 +name: brain dura mater +xref: EMAPS:3266828 +is_a: MA:0001115 ! dura mater +relationship: part_of MA:0000813 ! brain meninges + +[Term] +id: MA:0000816 +name: brain pia mater +xref: EMAPS:3266728 +is_a: MA:0001116 ! pia mater +relationship: part_of MA:0000813 ! brain meninges + +[Term] +id: MA:0000817 +name: brain subventricular zone +synonym: "SVZ" RELATED [] +xref: EMAPS:3280428 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000818 +name: brain ventricle +xref: EMAPS:3267428 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000819 +name: brain ventricular zone +synonym: "VZ" RELATED [] +xref: EMAPS:3267928 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000820 +name: brain white matter +xref: EMAPS:3518728 +is_a: MA:0001135 ! white matter +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0000821 +name: brainstem nucleus +xref: EMAPS:3279028 +is_a: MA:0000811 ! brain nucleus +relationship: part_of MA:0000169 ! brainstem + +[Term] +id: MA:0000822 +name: brainstem periaqueductal grey +is_a: MA:0002895 ! periaqueductal grey +relationship: part_of MA:0000169 ! brainstem + +[Term] +id: MA:0000823 +name: choroid plexus +xref: EMAPS:3274128 +relationship: part_of MA:0000168 ! brain +relationship: part_of MA:0000818 ! brain ventricle + +[Term] +id: MA:0000824 +name: choroid plexus epithelium +relationship: part_of MA:0000823 ! choroid plexus + +[Term] +id: MA:0000825 +name: choroid plexus stroma +relationship: part_of MA:0000823 ! choroid plexus + +[Term] +id: MA:0000826 +name: diencephalon meninges +xref: EMAPS:1776428 +relationship: part_of MA:0000171 ! diencephalon + +[Term] +id: MA:0000827 +name: diencephalon arachnoid mater +xref: EMAPS:1776528 +is_a: MA:0000884 ! forebrain arachnoid mater +relationship: part_of MA:0000826 ! diencephalon meninges + +[Term] +id: MA:0000828 +name: diencephalon dura mater +xref: EMAPS:1776628 +is_a: MA:0000885 ! forebrain dura mater +relationship: part_of MA:0000826 ! diencephalon meninges + +[Term] +id: MA:0000829 +name: diencephalon pia mater +xref: EMAPS:1776728 +is_a: MA:0000886 ! forebrain pia mater +relationship: part_of MA:0000826 ! diencephalon meninges + +[Term] +id: MA:0000830 +name: habenula +synonym: "habenular nucleus" RELATED [] +xref: EMAPS:3538628 +relationship: part_of MA:0000172 ! epithalamus + +[Term] +id: MA:0000831 +name: lateral habenular nucleus +xref: EMAPS:3547928 +relationship: part_of MA:0000830 ! habenula + +[Term] +id: MA:0000832 +name: medial habenular nucleus +xref: EMAPS:3554728 +relationship: part_of MA:0000830 ! habenula + +[Term] +id: MA:0000833 +name: hypothalamus lateral zone +xref: EMAPS:3541828 +relationship: part_of MA:0000173 ! hypothalamus + +[Term] +id: MA:0000834 +name: lateral hypothalamic area +synonym: "lateral hypothalamic nucleus" RELATED [] +xref: EMAPS:3548028 +relationship: part_of MA:0000833 ! hypothalamus lateral zone + +[Term] +id: MA:0000835 +name: lateral preoptic area +xref: EMAPS:3548328 +relationship: part_of MA:0000833 ! hypothalamus lateral zone + +[Term] +id: MA:0000836 +name: perifornical nucleus +relationship: part_of MA:0000833 ! hypothalamus lateral zone + +[Term] +id: MA:0000837 +name: hypothalamus medial zone +xref: EMAPS:3541928 +relationship: part_of MA:0000173 ! hypothalamus + +[Term] +id: MA:0000838 +name: dorsomedial hypothalamic nucleus +xref: EMAPS:3529728 +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000839 +name: medial preoptic region +xref: EMAPS:3555028 +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000840 +name: medial preoptic nucleus +xref: EMAPS:3554928 +relationship: part_of MA:0000839 ! medial preoptic region + +[Term] +id: MA:0000841 +name: retrochiasmatic area +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000842 +name: subparaventricular zone +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000843 +name: suprachiasmatic nucleus +xref: EMAPS:3584128 +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000844 +name: tuberal area +synonym: "tuberal nucleus" RELATED [] +synonym: "tuberal region" RELATED [] +xref: EMAPS:3542028 +relationship: part_of MA:0000837 ! hypothalamus medial zone + +[Term] +id: MA:0000845 +name: ventromedial hypothalamic nucleus +xref: EMAPS:3591628 +relationship: part_of MA:0000844 ! tuberal area + +[Term] +id: MA:0000846 +name: hypothalamus periventricular zone +xref: EMAPS:3542128 +relationship: part_of MA:0000173 ! hypothalamus + +[Term] +id: MA:0000847 +name: arcuate nucleus +xref: EMAPS:3514228 +relationship: part_of MA:0000846 ! hypothalamus periventricular zone + +[Term] +id: MA:0000848 +name: paraventricular hypothalamic nucleus +xref: EMAPS:3566528 +relationship: part_of MA:0000846 ! hypothalamus periventricular zone + +[Term] +id: MA:0000849 +name: supraoptic nucleus +xref: EMAPS:3584328 +relationship: part_of MA:0000846 ! hypothalamus periventricular zone + +[Term] +id: MA:0000850 +name: lateral mammillary nucleus +xref: EMAPS:3548128 +relationship: part_of MA:0000174 ! mammillary body + +[Term] +id: MA:0000851 +name: medial mammillary nucleus +xref: EMAPS:3554828 +relationship: part_of MA:0000174 ! mammillary body + +[Term] +id: MA:0000852 +name: supramammillary nucleus +xref: EMAPS:3584228 +relationship: part_of MA:0000174 ! mammillary body + +[Term] +id: MA:0000853 +name: tuberomammillary nucleus +xref: EMAPS:3588928 +relationship: part_of MA:0000174 ! mammillary body + +[Term] +id: MA:0000854 +name: pars anterior +synonym: "anterior lobe" RELATED [] +synonym: "pars distalis" RELATED [] +synonym: "pars glandularis" RELATED [] +xref: EMAPS:1751528 +relationship: part_of MA:0000177 ! adenohypophysis + +[Term] +id: MA:0000855 +name: pars intermedia +xref: EMAPS:1751628 +relationship: part_of MA:0000177 ! adenohypophysis + +[Term] +id: MA:0000856 +name: pars tuberalis +xref: EMAPS:1751728 +relationship: part_of MA:0000177 ! adenohypophysis + +[Term] +id: MA:0000857 +name: remnant of Rathke's pouch +synonym: "hypophyseal cleft" RELATED [] +xref: EMAPS:1751828 +relationship: part_of MA:0000177 ! adenohypophysis + +[Term] +id: MA:0000858 +name: infundibulum +xref: EMAPS:1752028 +relationship: part_of MA:0000178 ! neurohypophysis + +[Term] +id: MA:0000859 +name: median eminence +xref: EMAPS:1752128 +relationship: part_of MA:0000178 ! neurohypophysis + +[Term] +id: MA:0000860 +name: pars posterior +synonym: "neural lobe" RELATED [] +synonym: "pars nervosa" RELATED [] +synonym: "posterior lobe" RELATED [] +xref: EMAPS:3559528 +relationship: part_of MA:0000178 ! neurohypophysis + +[Term] +id: MA:0000861 +name: anterior thalamic group +xref: EMAPS:3513228 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000862 +name: lateral thalamic group +xref: EMAPS:3548728 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000863 +name: medial thalamic group +xref: EMAPS:3529628 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000864 +name: midline thalamic group +xref: EMAPS:3557328 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000865 +name: nucleus reuniens +xref: EMAPS:3560228 +relationship: part_of MA:0000864 ! midline thalamic group + +[Term] +id: MA:0000866 +name: paraventricular thalamic nucleus +xref: EMAPS:3566628 +relationship: part_of MA:0000864 ! midline thalamic group + +[Term] +id: MA:0000867 +name: ventral posterior thalamic group +xref: EMAPS:3591228 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000868 +name: geniculate thalamic group +xref: EMAPS:3537628 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000869 +name: lateral geniculate nucleus +synonym: "lateral geniculate body" RELATED [] +xref: EMAPS:3547828 +relationship: part_of MA:0000868 ! geniculate thalamic group + +[Term] +id: MA:0000870 +name: medial geniculate nucleus +xref: EMAPS:3554628 +relationship: part_of MA:0000868 ! geniculate thalamic group + +[Term] +id: MA:0000871 +name: intralaminar thalamic group +xref: EMAPS:3544528 +relationship: part_of MA:0000180 ! dorsal thalamus + +[Term] +id: MA:0000872 +name: central medial nucleus +xref: EMAPS:3520628 +relationship: part_of MA:0000871 ! intralaminar thalamic group + +[Term] +id: MA:0000873 +name: paracentral nucleus +xref: EMAPS:3565828 +relationship: part_of MA:0000871 ! intralaminar thalamic group + +[Term] +id: MA:0000874 +name: parafascicular nucleus +xref: EMAPS:3565928 +relationship: part_of MA:0000871 ! intralaminar thalamic group + +[Term] +id: MA:0000875 +name: peripeduncular nucleus +relationship: part_of MA:0000181 ! ventral thalamus + +[Term] +id: MA:0000876 +name: reticular thalamic nucleus +xref: EMAPS:3573728 +relationship: part_of MA:0000181 ! ventral thalamus + +[Term] +id: MA:0000877 +name: subthalamic nucleus +xref: EMAPS:3583928 +relationship: part_of MA:0000181 ! ventral thalamus + +[Term] +id: MA:0000878 +name: zona incerta +xref: EMAPS:3593028 +relationship: part_of MA:0000181 ! ventral thalamus + +[Term] +id: MA:0000879 +name: 3rd ventricle choroid plexus +synonym: "third ventricle choroid plexus" RELATED [] +xref: EMAPS:1854328 +is_a: MA:0000823 ! choroid plexus +relationship: part_of MA:0000182 ! 3rd ventricle + +[Term] +id: MA:0000880 +name: third ventricle choroid plexus epithelium +is_a: MA:0000824 ! choroid plexus epithelium +relationship: part_of MA:0000879 ! 3rd ventricle choroid plexus + +[Term] +id: MA:0000881 +name: third ventricle choroid plexus stroma +is_a: MA:0000825 ! choroid plexus stroma +relationship: part_of MA:0000879 ! 3rd ventricle choroid plexus + +[Term] +id: MA:0000882 +name: 3rd ventricle ependyma +synonym: "third ventricle ependyma" RELATED [] +xref: EMAPS:3510028 +is_a: MA:0000809 ! brain ependyma +relationship: part_of MA:0000182 ! 3rd ventricle + +[Term] +id: MA:0000883 +name: forebrain meninges +is_a: MA:0000813 ! brain meninges +relationship: part_of MA:0000170 ! forebrain + +[Term] +id: MA:0000884 +name: forebrain arachnoid mater +is_a: MA:0000814 ! brain arachnoid matter +relationship: part_of MA:0000883 ! forebrain meninges + +[Term] +id: MA:0000885 +name: forebrain dura mater +is_a: MA:0000815 ! brain dura mater +relationship: part_of MA:0000883 ! forebrain meninges + +[Term] +id: MA:0000886 +name: forebrain pia mater +is_a: MA:0000816 ! brain pia mater +relationship: part_of MA:0000883 ! forebrain meninges + +[Term] +id: MA:0000887 +name: amygdala +synonym: "amygdaloid area" RELATED [] +xref: EMAPS:3267228 +relationship: part_of MA:0000184 ! basal ganglia + +[Term] +id: MA:0000888 +name: claustrum +xref: EMAPS:3524428 +relationship: part_of MA:0000184 ! basal ganglia + +[Term] +id: MA:0000889 +name: pallidum +xref: EMAPS:3278028 +relationship: part_of MA:0000184 ! basal ganglia + +[Term] +id: MA:0000890 +name: globus pallidus +xref: EMAPS:3538028 +relationship: part_of MA:0000889 ! pallidum + +[Term] +id: MA:0000891 +name: striatum +synonym: "corpus striatum" RELATED [] +xref: EMAPS:1754928 +relationship: part_of MA:0000184 ! basal ganglia + +[Term] +id: MA:0000892 +name: accumbens nucleus +synonym: "nucleus accumbens" RELATED [] +xref: EMAPS:3278928 +relationship: part_of MA:0002972 ! ventral striatum + +[Term] +id: MA:0000893 +name: caudate-putamen +synonym: "caudate putamen" RELATED [] +xref: EMAPS:1909528 +relationship: part_of MA:0002971 ! dorsal striatum + +[Term] +id: MA:0000894 +name: caudate nucleus +xref: EMAPS:1820728 +relationship: part_of MA:0000893 ! caudate-putamen + +[Term] +id: MA:0000895 +name: putamen +xref: EMAPS:3571928 +relationship: part_of MA:0000893 ! caudate-putamen + +[Term] +id: MA:0000896 +name: lentiform nucleus +xref: EMAPS:1820828 +relationship: part_of MA:0002972 ! ventral striatum + +[Term] +id: MA:0000897 +name: cortical layer I +synonym: "molecular layer" RELATED [] +synonym: "plexiform layer" RELATED [] +xref: EMAPS:3525528 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000898 +name: cortical layer II +synonym: "external granular layer" RELATED [] +xref: EMAPS:3525628 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000899 +name: cortical layer III +synonym: "pyramidal layer" RELATED [] +xref: EMAPS:3525728 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000900 +name: cortical layer IV +synonym: "internal granular layer" RELATED [] +xref: EMAPS:3525828 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000901 +name: cortical layer V +synonym: "ganglionic layer" RELATED [] +xref: EMAPS:3525928 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000902 +name: cortical layer VI +synonym: "multiform layer" RELATED [] +xref: EMAPS:3526028 +is_a: MA:0000186 ! neocortex layer + +[Term] +id: MA:0000903 +name: anterior medial cortex +xref: EMAPS:3513028 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000904 +name: cingulate cortex +xref: EMAPS:3524228 +relationship: part_of MA:0000903 ! anterior medial cortex + +[Term] +id: MA:0000905 +name: frontal cortex +xref: EMAPS:3535728 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000906 +name: frontal association cortex +synonym: "prefrontal cortex" RELATED [] +xref: EMAPS:3535628 +relationship: part_of MA:0000905 ! frontal cortex + +[Term] +id: MA:0000907 +name: primary motor cortex +xref: EMAPS:3570428 +relationship: part_of MA:0000905 ! frontal cortex +relationship: part_of MA:0000916 ! parietal cortex + +[Term] +id: MA:0000908 +name: primary somatosensory cortex +xref: EMAPS:3570628 +relationship: part_of MA:0000905 ! frontal cortex +relationship: part_of MA:0000916 ! parietal cortex + +[Term] +id: MA:0000909 +name: insular cortex +xref: EMAPS:3543228 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000910 +name: spinal cord white matter +xref: EMAPS:3579528 +is_a: MA:0001135 ! white matter +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0000911 +name: lateral entorhinal cortex +xref: EMAPS:3547728 +relationship: part_of MA:0000909 ! insular cortex +relationship: part_of MA:0003117 ! entorhinal cortex + +[Term] +id: MA:0000912 +name: perirhinal cortex +xref: EMAPS:3568228 +relationship: part_of MA:0000909 ! insular cortex + +[Term] +id: MA:0000913 +name: occipital cortex +xref: EMAPS:3560428 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000914 +name: primary visual cortex +xref: EMAPS:3570828 +relationship: part_of MA:0000913 ! occipital cortex + +[Term] +id: MA:0000915 +name: secondary visual cortex +xref: EMAPS:3575828 +relationship: part_of MA:0000913 ! occipital cortex + +[Term] +id: MA:0000916 +name: parietal cortex +xref: EMAPS:3566728 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000917 +name: gut +xref: EMAPS:1624728 +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0000918 +name: secondary somatosensory cortex +xref: EMAPS:3575628 +relationship: part_of MA:0000916 ! parietal cortex + +[Term] +id: MA:0000919 +name: upper lip +xref: EMAPS:1792528 +is_a: MA:0000343 ! lip + +[Term] +id: MA:0000920 +name: retrohippocampal cortex +xref: EMAPS:3574528 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000921 +name: lower lip +xref: EMAPS:1790928 +is_a: MA:0000343 ! lip + +[Term] +id: MA:0000922 +name: medial entorhinal cortex +xref: EMAPS:3554528 +relationship: part_of MA:0003117 ! entorhinal cortex + +[Term] +id: MA:0000923 +name: presubiculum +xref: EMAPS:3570328 +relationship: part_of MA:0000920 ! retrohippocampal cortex + +[Term] +id: MA:0000924 +name: septum of telencephalon +synonym: "septal area" RELATED [] +synonym: "septum" RELATED [] +xref: EMAPS:3283728 +relationship: part_of MA:0000133 ! cerebral hemisphere + +[Term] +id: MA:0000925 +name: bed nucleus of stria terminalis +xref: EMAPS:3516928 +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000926 +name: anterior division of bed nucleus of stria terminalis +relationship: part_of MA:0000925 ! bed nucleus of stria terminalis + +[Term] +id: MA:0000927 +name: fusiform nucleus +relationship: part_of MA:0000926 ! anterior division of bed nucleus of stria terminalis + +[Term] +id: MA:0000928 +name: magnocellular nucleus +relationship: part_of MA:0000926 ! anterior division of bed nucleus of stria terminalis + +[Term] +id: MA:0000929 +name: oval nucleus +relationship: part_of MA:0000926 ! anterior division of bed nucleus of stria terminalis + +[Term] +id: MA:0000930 +name: posterior division of bed nucleus of stria terminalis +relationship: part_of MA:0000925 ! bed nucleus of stria terminalis + +[Term] +id: MA:0000931 +name: principal nucleus +relationship: part_of MA:0000930 ! posterior division of bed nucleus of stria terminalis + +[Term] +id: MA:0000932 +name: transverse nucleus +relationship: part_of MA:0000930 ! posterior division of bed nucleus of stria terminalis + +[Term] +id: MA:0000933 +name: lateral septal complex +xref: EMAPS:3548528 +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000934 +name: medial septal complex +xref: EMAPS:3555228 +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000935 +name: medial septal nucleus +xref: EMAPS:3555328 +relationship: part_of MA:0000934 ! medial septal complex + +[Term] +id: MA:0000936 +name: nucleus of diagonal band +xref: EMAPS:3559828 +relationship: part_of MA:0000934 ! medial septal complex + +[Term] +id: MA:0000937 +name: posterior septal complex +xref: EMAPS:3569628 +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000938 +name: septofimbrial nucleus +xref: EMAPS:3576728 +relationship: part_of MA:0000937 ! posterior septal complex + +[Term] +id: MA:0000939 +name: septohippocampal nucleus +xref: EMAPS:3576828 +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000940 +name: subfornical organ +xref: EMAPS:3583028 +is_a: MA:0002944 ! sensory circumventricular organ +is_a: MA:0002978 ! septal nucleus + +[Term] +id: MA:0000941 +name: temporal cortex +synonym: "temporal lobe" RELATED [] +xref: EMAPS:1879728 +is_a: MA:0000187 ! neocortex region + +[Term] +id: MA:0000942 +name: auditory cortex +xref: EMAPS:3515628 +relationship: part_of MA:0000941 ! temporal cortex + +[Term] +id: MA:0000943 +name: temporal cortex association area +xref: EMAPS:3585228 +relationship: part_of MA:0000941 ! temporal cortex + +[Term] +id: MA:0000944 +name: cerebral grey matter +is_a: MA:0000810 ! brain grey matter +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000945 +name: cerebral white matter +xref: EMAPS:3523728 +is_a: MA:0000820 ! brain white matter +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000946 +name: dentate gyrus granule cell layer +xref: EMAPS:3527628 +is_a: MA:0002429 ! dentate gyrus layer + +[Term] +id: MA:0000947 +name: dentate gyrus hilus +xref: EMAPS:3527728 +relationship: part_of MA:0000190 ! dentate gyrus + +[Term] +id: MA:0000948 +name: dentate gyrus pyramidal layer +is_a: MA:0002429 ! dentate gyrus layer + +[Term] +id: MA:0000949 +name: fimbria hippocampus +xref: EMAPS:3534528 +relationship: part_of MA:0000191 ! hippocampus + +[Term] +id: MA:0000950 +name: hippocampus CA1 +xref: EMAPS:3276828 +is_a: MA:0002428 ! hippocampus region + +[Term] +id: MA:0000951 +name: hippocampus CA2 +xref: EMAPS:3276928 +is_a: MA:0002428 ! hippocampus region + +[Term] +id: MA:0000952 +name: hippocampus CA3 +xref: EMAPS:3277028 +is_a: MA:0002428 ! hippocampus region + +[Term] +id: MA:0000953 +name: hippocampus CA4 +xref: EMAPS:3277128 +is_a: MA:0002428 ! hippocampus region + +[Term] +id: MA:0000954 +name: hippocampus granule cell layer +xref: EMAPS:3540628 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000955 +name: hippocampus molecular layer +synonym: "hippocampus stratum moleculare" RELATED [] +xref: EMAPS:3540828 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000956 +name: hippocampus pyramidal layer +synonym: "hippocampus stratum pyramidale" RELATED [] +xref: EMAPS:3540928 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000957 +name: hippocampus stratum lacunosum +xref: EMAPS:3541028 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000958 +name: hippocampus stratum oriens +xref: EMAPS:3541228 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000959 +name: hippocampus stratum radiatum +xref: EMAPS:3541328 +is_a: MA:0002427 ! hippocampus layer + +[Term] +id: MA:0000960 +name: subiculum +xref: EMAPS:3583228 +relationship: part_of MA:0000189 ! hippocampal formation + +[Term] +id: MA:0000961 +name: lateral ventricle choroid plexus +xref: EMAPS:1776928 +is_a: MA:0000823 ! choroid plexus +relationship: part_of MA:0000192 ! lateral ventricle + +[Term] +id: MA:0000962 +name: lateral ventricle choroid plexus epithelium +is_a: MA:0000824 ! choroid plexus epithelium +relationship: part_of MA:0000961 ! lateral ventricle choroid plexus + +[Term] +id: MA:0000963 +name: lateral ventricle choroid plexus stroma +is_a: MA:0000825 ! choroid plexus stroma +relationship: part_of MA:0000961 ! lateral ventricle choroid plexus + +[Term] +id: MA:0000964 +name: lateral ventricle ependyma +xref: EMAPS:3548828 +is_a: MA:0000809 ! brain ependyma +relationship: part_of MA:0000192 ! lateral ventricle + +[Term] +id: MA:0000965 +name: lateral ventricle subependymal layer +xref: EMAPS:3548928 +relationship: part_of MA:0000192 ! lateral ventricle + +[Term] +id: MA:0000966 +name: accessory olfactory bulb +synonym: "accessory olfactory formation" RELATED [] +xref: EMAPS:3510628 +relationship: part_of MA:0002413 ! olfactory lobe + +[Term] +id: MA:0000967 +name: accessory olfactory bulb glomerular layer +xref: EMAPS:3510828 +relationship: part_of MA:0000966 ! accessory olfactory bulb + +[Term] +id: MA:0000968 +name: anterior olfactory nucleus +xref: EMAPS:3513128 +relationship: part_of MA:0000193 ! olfactory cortex + +[Term] +id: MA:0000969 +name: olfactory bulb external plexiform layer +xref: EMAPS:3560728 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000970 +name: olfactory bulb glomerular layer +xref: EMAPS:3560828 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000971 +name: olfactory bulb granule cell layer +xref: EMAPS:3560928 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000972 +name: olfactory bulb internal plexiform layer +xref: EMAPS:3561028 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000973 +name: olfactory bulb mitral cell layer +xref: EMAPS:3561128 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000974 +name: olfactory bulb subependymal zone +xref: EMAPS:3561228 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0000975 +name: olfactory tract +xref: EMAPS:3561528 +relationship: part_of MA:0000193 ! olfactory cortex + +[Term] +id: MA:0000976 +name: olfactory tubercle +xref: EMAPS:3561628 +relationship: part_of MA:0000193 ! olfactory cortex + +[Term] +id: MA:0000977 +name: islands of Calleja +xref: EMAPS:3545228 +relationship: part_of MA:0000976 ! olfactory tubercle + +[Term] +id: MA:0000978 +name: piriform cortex +synonym: "piriform area" RELATED [] +xref: EMAPS:3276728 +relationship: part_of MA:0000193 ! olfactory cortex + +[Term] +id: MA:0000979 +name: telencephalon meninges +xref: EMAPS:1777428 +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0000980 +name: telencephalon arachnoid matter +xref: EMAPS:1777528 +is_a: MA:0000884 ! forebrain arachnoid mater +relationship: part_of MA:0000979 ! telencephalon meninges + +[Term] +id: MA:0000981 +name: telencephalon dura mater +xref: EMAPS:1777628 +is_a: MA:0000885 ! forebrain dura mater +relationship: part_of MA:0000979 ! telencephalon meninges + +[Term] +id: MA:0000982 +name: telencephalon pia mater +xref: EMAPS:1777728 +is_a: MA:0000886 ! forebrain pia mater +relationship: part_of MA:0000979 ! telencephalon meninges + +[Term] +id: MA:0000983 +name: 4th ventricle choroid plexus +synonym: "fourth ventricle choroid plexus" RELATED [] +xref: EMAPS:3274228 +is_a: MA:0000823 ! choroid plexus +relationship: part_of MA:0000196 ! 4th ventricle + +[Term] +id: MA:0000984 +name: 4th ventricle choroid plexus epithelium +is_a: MA:0000824 ! choroid plexus epithelium +relationship: part_of MA:0000983 ! 4th ventricle choroid plexus + +[Term] +id: MA:0000985 +name: 4th ventricle choroid plexus stroma +is_a: MA:0000825 ! choroid plexus stroma +relationship: part_of MA:0000983 ! 4th ventricle choroid plexus + +[Term] +id: MA:0000986 +name: 4th ventricle ependyma +synonym: "fourth ventricle ependyma" RELATED [] +xref: EMAPS:3535528 +is_a: MA:0000809 ! brain ependyma +relationship: part_of MA:0000196 ! 4th ventricle + +[Term] +id: MA:0000987 +name: hindbrain meninges +xref: EMAPS:1778328 +is_a: MA:0000813 ! brain meninges +relationship: part_of MA:0000195 ! hindbrain + +[Term] +id: MA:0000988 +name: hindbrain arachnoid mater +xref: EMAPS:1778428 +is_a: MA:0000814 ! brain arachnoid matter +relationship: part_of MA:0000987 ! hindbrain meninges + +[Term] +id: MA:0000989 +name: hindbrain dura mater +xref: EMAPS:1778528 +is_a: MA:0000815 ! brain dura mater +relationship: part_of MA:0000987 ! hindbrain meninges + +[Term] +id: MA:0000990 +name: hindbrain pia mater +xref: EMAPS:1778628 +is_a: MA:0000816 ! brain pia mater +relationship: part_of MA:0000987 ! hindbrain meninges + +[Term] +id: MA:0000991 +name: cerebellum anterior lobe +xref: EMAPS:3521528 +is_a: MA:0002963 ! cerebellum lobe + +[Term] +id: MA:0000992 +name: flocculus +xref: EMAPS:3534628 +relationship: part_of MA:0000200 ! cerebellum hemisphere + +[Term] +id: MA:0000993 +name: cerebellum granule cell layer +xref: EMAPS:3521728 +is_a: MA:0000201 ! cerebellar layer + +[Term] +id: MA:0000994 +name: cerebellum external granule cell layer +xref: EMAPS:3521628 +is_a: MA:0000993 ! cerebellum granule cell layer + +[Term] +id: MA:0000995 +name: cerebellum internal granule cell layer +xref: EMAPS:3521928 +is_a: MA:0000993 ! cerebellum granule cell layer + +[Term] +id: MA:0000996 +name: cerebellum molecular cell layer +xref: EMAPS:3522128 +is_a: MA:0000201 ! cerebellar layer + +[Term] +id: MA:0000997 +name: cerebellum purkinje cell layer +xref: EMAPS:3522328 +is_a: MA:0000201 ! cerebellar layer + +[Term] +id: MA:0000998 +name: cerebellum vermis lobule I +synonym: "lingula" RELATED [] +xref: EMAPS:3522528 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002969 ! anterior cerebellum vermis + +[Term] +id: MA:0000999 +name: cerebellum vermis lobule II +synonym: "central lobule" RELATED [] +xref: EMAPS:3522628 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002969 ! anterior cerebellum vermis + +[Term] +id: MA:0001000 +name: cerebellum vermis lobule III +synonym: "central lobule" RELATED [] +xref: EMAPS:3522728 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002969 ! anterior cerebellum vermis + +[Term] +id: MA:0001001 +name: cerebellum vermis lobule IV +synonym: "culmen" RELATED [] +xref: EMAPS:3522828 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002969 ! anterior cerebellum vermis + +[Term] +id: MA:0001002 +name: cerebellum vermis lobule V +synonym: "culmen" RELATED [] +xref: EMAPS:3523028 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002969 ! anterior cerebellum vermis + +[Term] +id: MA:0001003 +name: cerebellum vermis lobule VI +synonym: "declive" RELATED [] +xref: EMAPS:3523128 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002970 ! posterior cerebellum vermis + +[Term] +id: MA:0001004 +name: cerebellum vermis lobule VII +synonym: "folium" RELATED [] +xref: EMAPS:3523228 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002970 ! posterior cerebellum vermis + +[Term] +id: MA:0001005 +name: cerebellum vermis lobule VIII +synonym: "pyramus" RELATED [] +xref: EMAPS:3523328 +is_a: MA:0002968 ! cerebellum vermis lobule +relationship: part_of MA:0002970 ! posterior cerebellum vermis + +[Term] +id: MA:0001006 +name: cerebellum vermis lobule IX +synonym: "uvula" RELATED [] +xref: EMAPS:3522928 +is_a: MA:0002968 ! cerebellum vermis lobule + +[Term] +id: MA:0001007 +name: cerebellum vermis lobule X +synonym: "nodulus" RELATED [] +xref: EMAPS:3523428 +is_a: MA:0002968 ! cerebellum vermis lobule + +[Term] +id: MA:0001008 +name: lateral cerebellar nucleus +synonym: "dentate nucleus" RELATED [] +is_a: MA:0000203 ! deep cerebellar nucleus + +[Term] +id: MA:0001009 +name: medial cerebellar nucleus +synonym: "fastigial nucleus" RELATED [] +is_a: MA:0000203 ! deep cerebellar nucleus + +[Term] +id: MA:0001010 +name: abducens VI nucleus +xref: EMAPS:3510528 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001011 +name: barrington's nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001012 +name: cochlear VIII nucleus +xref: EMAPS:3524828 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001013 +name: dorsal tegmental nucleus +xref: EMAPS:3529428 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001014 +name: facial VII nucleus +alt_id: MA:0001015 +synonym: "facial VII motor nucleus" RELATED [] +xref: EMAPS:3533828 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001016 +name: laterodorsal tegmental nucleus +xref: EMAPS:3549028 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001017 +name: locus coeruleus +xref: EMAPS:3550228 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001018 +name: nucleus of trapezoid body +xref: EMAPS:3560028 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001019 +name: parabrachial nucleus +xref: EMAPS:3565728 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001020 +name: peduncular pontine nucleus +xref: EMAPS:3567228 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001021 +name: pontine nucleus +xref: EMAPS:3569228 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001022 +name: pontine raphe nucleus +synonym: "raphe pontis nucleus" RELATED [] +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001023 +name: prepositus hypoglossal nucleus +synonym: "nucleus prepositus hypoglossus" RELATED [] +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001024 +name: raphe magnus nucleus +xref: EMAPS:3572028 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001025 +name: reticular tegmental nucleus +synonym: "reticulotegmental nucleus" RELATED [] +xref: EMAPS:3573628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001026 +name: superior olivary nucleus +synonym: "superior olive" RELATED [] +xref: EMAPS:3584028 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001027 +name: superior salivatory nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001028 +name: trigeminal V nucleus +xref: EMAPS:3588328 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001029 +name: trigeminal V motor nucleus +xref: EMAPS:3588228 +relationship: part_of MA:0001028 ! trigeminal V nucleus + +[Term] +id: MA:0001030 +name: trigeminal V sensory nucleus +xref: EMAPS:3588428 +relationship: part_of MA:0001028 ! trigeminal V nucleus + +[Term] +id: MA:0001031 +name: ventral tegmental nucleus +synonym: "nucleus of gudden" RELATED [] +xref: EMAPS:3591428 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001032 +name: vestibular VIII nucleus +xref: EMAPS:3592328 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000204 ! pons + +[Term] +id: MA:0001033 +name: accessory XI nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001034 +name: area postrema +xref: EMAPS:3514328 +is_a: MA:0002944 ! sensory circumventricular organ +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001035 +name: cuneate nucleus +xref: EMAPS:3526828 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001036 +name: dorsal motor nucleus of vagus X nerve +xref: EMAPS:3529128 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001037 +name: gigantocellular reticular nucleus +xref: EMAPS:3537828 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001038 +name: gracile nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001039 +name: hypoglossal XII nucleus +xref: EMAPS:3541628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001040 +name: inferior olive +xref: EMAPS:1924128 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001041 +name: inferior olive beta subnucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001042 +name: inferior olive dorsal accessory nucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001043 +name: inferior olive inferior nucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001044 +name: inferior olive medial accessory nucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001045 +name: inferior olive medial nucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001046 +name: inferior olive principal nucleus +relationship: part_of MA:0001040 ! inferior olive + +[Term] +id: MA:0001047 +name: lateral reticular nucleus +xref: EMAPS:3548428 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001048 +name: medial vestibular nucleus +xref: EMAPS:3555428 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001049 +name: medullary reticular nucleus +xref: EMAPS:3555628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001050 +name: nucleus ambiguus +xref: EMAPS:3559628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001051 +name: raphe pallidus nucleus +xref: EMAPS:3572228 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001052 +name: solitary tract nucleus +xref: EMAPS:3578728 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001053 +name: trigeminal V spinal sensory nucleus +synonym: "spinal trigeminal nucleus" RELATED [] +xref: EMAPS:3588528 +is_a: MA:0001030 ! trigeminal V sensory nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001054 +name: spinal vestibular nucleus +xref: EMAPS:3579728 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0001055 +name: anterior tegmental nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0001056 +name: crura cerebri +is_a: MA:0002741 ! brainstem white matter +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0001057 +name: trigeminal V mesencephalic nucleus +xref: EMAPS:3588128 +is_a: MA:0001030 ! trigeminal V sensory nucleus +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0001058 +name: midbrain meninges +xref: EMAPS:1779128 +is_a: MA:0000813 ! brain meninges +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0001059 +name: midbrain arachnoid mater +xref: EMAPS:1779228 +is_a: MA:0000814 ! brain arachnoid matter +relationship: part_of MA:0001058 ! midbrain meninges + +[Term] +id: MA:0001060 +name: midbrain dura mater +xref: EMAPS:1779328 +is_a: MA:0000815 ! brain dura mater +relationship: part_of MA:0001058 ! midbrain meninges + +[Term] +id: MA:0001061 +name: midbrain pia mater +xref: EMAPS:1779428 +is_a: MA:0000816 ! brain pia mater +relationship: part_of MA:0001058 ! midbrain meninges + +[Term] +id: MA:0001062 +name: pretectal region +synonym: "pretectum" RELATED [] +xref: EMAPS:3277828 +relationship: part_of MA:0000207 ! midbrain + +[Term] +id: MA:0001063 +name: red nucleus +xref: EMAPS:3572428 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001064 +name: substantia nigra pars compacta +xref: EMAPS:3583628 +relationship: part_of MA:0000210 ! substantia nigra + +[Term] +id: MA:0001065 +name: substantia nigra pars lateralis +xref: EMAPS:3583728 +relationship: part_of MA:0000210 ! substantia nigra + +[Term] +id: MA:0001066 +name: substantia nigra pars reticulata +xref: EMAPS:3583828 +relationship: part_of MA:0000210 ! substantia nigra + +[Term] +id: MA:0001067 +name: inferior colliculus +xref: EMAPS:3287028 +relationship: part_of MA:0002567 ! corpora quadrigemina + +[Term] +id: MA:0001068 +name: superior colliculus +xref: EMAPS:3286928 +relationship: part_of MA:0002567 ! corpora quadrigemina + +[Term] +id: MA:0001069 +name: interpeduncular nucleus +xref: EMAPS:3543928 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001070 +name: nucleus related to visual cortex +xref: EMAPS:3560128 +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001071 +name: edinger-westphal nucleus +xref: EMAPS:3530228 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001072 +name: nucleus of darkschewitsch +xref: EMAPS:3559728 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001073 +name: oculomotor III nucleus +xref: EMAPS:3560528 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001074 +name: parabigeminal nucleus +xref: EMAPS:3565628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001075 +name: trochlear IV nucleus +xref: EMAPS:3588628 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0001076 +name: facial VII ganglion +synonym: "geniculate ganglion" RELATED [] +xref: EMAPS:1756928 +is_a: MA:0000214 ! cranial ganglion + +[Term] +id: MA:0001077 +name: glossopharyngeal IX ganglion +xref: EMAPS:1679528 +is_a: MA:0000214 ! cranial ganglion + +[Term] +id: MA:0001078 +name: inferior glossopharyngeal IX ganglion +xref: EMAPS:1715328 +relationship: part_of MA:0001077 ! glossopharyngeal IX ganglion + +[Term] +id: MA:0001079 +name: superior glossopharyngeal IX ganglion +xref: EMAPS:1715428 +relationship: part_of MA:0001077 ! glossopharyngeal IX ganglion + +[Term] +id: MA:0001080 +name: trigeminal V ganglion +xref: EMAPS:1679728 +is_a: MA:0000214 ! cranial ganglion + +[Term] +id: MA:0001081 +name: vagus X ganglion +xref: EMAPS:1679828 +is_a: MA:0000214 ! cranial ganglion + +[Term] +id: MA:0001082 +name: inferior vagus X ganglion +xref: EMAPS:1715528 +relationship: part_of MA:0001081 ! vagus X ganglion + +[Term] +id: MA:0001083 +name: superior vagus X ganglion +xref: EMAPS:1715628 +relationship: part_of MA:0001081 ! vagus X ganglion + +[Term] +id: MA:0001084 +name: vestibulocochlear VIII ganglion +xref: EMAPS:1757128 +is_a: MA:0000214 ! cranial ganglion + +[Term] +id: MA:0001085 +name: vestibulocochlear VIII ganglion cochlear component +synonym: "spiral ganglion" RELATED [] +xref: EMAPS:1757228 +relationship: part_of MA:0001084 ! vestibulocochlear VIII ganglion + +[Term] +id: MA:0001086 +name: vestibulocochlear VIII ganglion vestibular component +synonym: "scarpa's ganglion" RELATED [] +synonym: "vestibular ganglion" RELATED [] +xref: EMAPS:1757328 +relationship: part_of MA:0001084 ! vestibulocochlear VIII ganglion + +[Term] +id: MA:0001087 +name: abducens VI nerve +xref: EMAPS:1821628 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001088 +name: accessory XI nerve +xref: EMAPS:1726528 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001089 +name: accessory XI nerve cranial component +xref: EMAPS:1726628 +relationship: part_of MA:0001088 ! accessory XI nerve + +[Term] +id: MA:0001090 +name: accessory XI nerve spinal component +xref: EMAPS:1726728 +is_a: MA:0000233 ! spinal nerve +relationship: part_of MA:0001088 ! accessory XI nerve + +[Term] +id: MA:0001091 +name: facial VII nerve +xref: EMAPS:1779628 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001092 +name: facial VII nerve chorda tympani branch +xref: EMAPS:1821728 +relationship: part_of MA:0001091 ! facial VII nerve + +[Term] +id: MA:0001093 +name: glossopharyngeal IX nerve +xref: EMAPS:1726828 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001094 +name: hypoglossal XII nerve +xref: EMAPS:1726928 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001095 +name: oculomotor III nerve +xref: EMAPS:1757428 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001096 +name: olfactory I nerve +xref: EMAPS:1779728 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001097 +name: optic II nerve +xref: EMAPS:1757528 +xref: EMAPS:1784628 +is_a: MA:0000215 ! cranial nerve +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0001098 +name: optic chiasm +xref: EMAPS:1760328 +relationship: part_of MA:0001097 ! optic II nerve + +[Term] +id: MA:0001099 +name: optic tract +xref: EMAPS:1667828 +xref: EMAPS:3561728 +relationship: part_of MA:0001097 ! optic II nerve + +[Term] +id: MA:0001100 +name: trigeminal V nerve +xref: EMAPS:1757628 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001101 +name: trigeminal V nerve mandibular division +xref: EMAPS:1779828 +relationship: part_of MA:0001100 ! trigeminal V nerve + +[Term] +id: MA:0001102 +name: trigeminal V nerve lingual branch +xref: EMAPS:1916828 +relationship: part_of MA:0001101 ! trigeminal V nerve mandibular division + +[Term] +id: MA:0001103 +name: trigeminal V nerve maxillary division +xref: EMAPS:1779928 +relationship: part_of MA:0001100 ! trigeminal V nerve + +[Term] +id: MA:0001104 +name: trigeminal V nerve ophthalmic division +xref: EMAPS:1780028 +relationship: part_of MA:0001100 ! trigeminal V nerve + +[Term] +id: MA:0001105 +name: trochlear IV nerve +xref: EMAPS:1821828 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001106 +name: vagus X nerve +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001107 +name: vagus X nerve left recurrent laryngeal branch +xref: EMAPS:2535028 +relationship: part_of MA:0001106 ! vagus X nerve + +[Term] +id: MA:0001108 +name: vagus X nerve right recurrent laryngeal branch +xref: EMAPS:1727528 +relationship: part_of MA:0001106 ! vagus X nerve + +[Term] +id: MA:0001109 +name: vestibulocochlear VIII nerve +xref: EMAPS:1780128 +is_a: MA:0000215 ! cranial nerve + +[Term] +id: MA:0001110 +name: vestibulocochlear VIII nerve cochlear component +xref: EMAPS:1780228 +relationship: part_of MA:0001109 ! vestibulocochlear VIII nerve + +[Term] +id: MA:0001111 +name: vestibulocochlear VIII nerve vestibular component +xref: EMAPS:1780328 +relationship: part_of MA:0001109 ! vestibulocochlear VIII nerve + +[Term] +id: MA:0001112 +name: grey matter +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0001113 +name: meninges +xref: EMAPS:3266028 +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0001114 +name: arachnoid mater +xref: EMAPS:3265928 +relationship: part_of MA:0001113 ! meninges + +[Term] +id: MA:0001115 +name: dura mater +xref: EMAPS:3266428 +relationship: part_of MA:0001113 ! meninges + +[Term] +id: MA:0001116 +name: pia mater +xref: EMAPS:3266328 +relationship: part_of MA:0001113 ! meninges + +[Term] +id: MA:0001117 +name: spinal cord central canal +xref: EMAPS:3578928 +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0001118 +name: spinal cord central grey +relationship: part_of MA:0000002 ! spinal cord grey matter + +[Term] +id: MA:0001119 +name: spinal cord dorsal horn +xref: EMAPS:3579028 +relationship: part_of MA:0000002 ! spinal cord grey matter + +[Term] +id: MA:0001120 +name: spinal cord basal nucleus +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0001121 +name: spinal cord dorsal nucleus +synonym: "clarke's nucleus" RELATED [] +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0001122 +name: spinal cord marginal zone +xref: EMAPS:1758328 +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0001123 +name: spinal cord reticular nucleus +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0001124 +name: substantia gelatinosa +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0001125 +name: spinal cord ependymal layer +synonym: "spinal cord ventricular layer" RELATED [] +xref: EMAPS:3579128 +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0001126 +name: spinal cord intermediate grey +xref: EMAPS:3569128 +relationship: part_of MA:0000002 ! spinal cord grey matter + +[Term] +id: MA:0001127 +name: spinal cord central cervical nucleus +relationship: part_of MA:0001126 ! spinal cord intermediate grey + +[Term] +id: MA:0001128 +name: spinal cord dorsal commissural nucleus +relationship: part_of MA:0001126 ! spinal cord intermediate grey + +[Term] +id: MA:0001129 +name: spinal cord lateral motor column +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0001130 +name: spinal cord meninges +xref: EMAPS:1780428 +is_a: MA:0001113 ! meninges +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0001131 +name: spinal cord arachnoid mater +xref: EMAPS:1780528 +is_a: MA:0001114 ! arachnoid mater +relationship: part_of MA:0001130 ! spinal cord meninges + +[Term] +id: MA:0001132 +name: spinal cord dura mater +xref: EMAPS:1780628 +is_a: MA:0001115 ! dura mater +relationship: part_of MA:0001130 ! spinal cord meninges + +[Term] +id: MA:0001133 +name: spinal cord pia mater +xref: EMAPS:1780728 +is_a: MA:0001116 ! pia mater +relationship: part_of MA:0001130 ! spinal cord meninges + +[Term] +id: MA:0001134 +name: spinal cord ventral horn +xref: EMAPS:3579428 +relationship: part_of MA:0000002 ! spinal cord grey matter + +[Term] +id: MA:0001135 +name: white matter +xref: EMAPS:3592728 +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0001136 +name: ciliary ganglion +xref: EMAPS:1822228 +is_a: MA:0002469 ! parasympathetic ganglion + +[Term] +id: MA:0001137 +name: organ of Zuckerkandl +synonym: "para-aortic body" RELATED [] +synonym: "paraganglia of zuckerkandl" RELATED [] +xref: EMAPS:1822328 +relationship: part_of MA:0000012 ! endocrine system + +[Term] +id: MA:0001138 +name: cardiac nerve plexus +is_a: MA:0000221 ! autonomic nerve plexus + +[Term] +id: MA:0001139 +name: celiac nerve plexus +synonym: "coeliac nerve plexus" RELATED [] +is_a: MA:0000221 ! autonomic nerve plexus + +[Term] +id: MA:0001140 +name: hypogastric nerve plexus +is_a: MA:0000221 ! autonomic nerve plexus + +[Term] +id: MA:0001141 +name: inferior hypogastric nerve plexus +relationship: part_of MA:0001140 ! hypogastric nerve plexus + +[Term] +id: MA:0001142 +name: superior hypogastric nerve plexus +relationship: part_of MA:0001140 ! hypogastric nerve plexus + +[Term] +id: MA:0001143 +name: pulmonary nerve plexus +is_a: MA:0000221 ! autonomic nerve plexus + +[Term] +id: MA:0001144 +name: enteric ganglion +xref: EMAPS:3531228 +is_a: MA:0001161 ! peripheral nervous system ganglion +relationship: part_of MA:0000222 ! enteric nervous system + +[Term] +id: MA:0001145 +name: enteric nerve +is_a: MA:0000217 ! nerve +relationship: part_of MA:0000222 ! enteric nervous system + +[Term] +id: MA:0001146 +name: cholinergic enteric nerve +is_a: MA:0001145 ! enteric nerve + +[Term] +id: MA:0001147 +name: intrinsic nerve plexus +xref: EMAPS:3544628 +is_a: MA:0002407 ! nerve plexus +relationship: part_of MA:0000222 ! enteric nervous system + +[Term] +id: MA:0001148 +name: myenteric nerve plexus +synonym: "auerbach's plexus" RELATED [] +xref: EMAPS:3284728 +is_a: MA:0001147 ! intrinsic nerve plexus + +[Term] +id: MA:0001149 +name: submucous nerve plexus +synonym: "henle's plexus" RELATED [] +synonym: "meissner's plexus" RELATED [] +xref: EMAPS:3583428 +is_a: MA:0001147 ! intrinsic nerve plexus + +[Term] +id: MA:0001150 +name: vagus X nerve trunk +xref: EMAPS:1727228 +is_a: MA:0000224 ! parasympathetic nerve + +[Term] +id: MA:0001151 +name: left vagus X nerve trunk +synonym: "anterior vagus X nerve trunk" RELATED [] +relationship: part_of MA:0001150 ! vagus X nerve trunk + +[Term] +id: MA:0001152 +name: right vagus X nerve trunk +synonym: "posterior vagus X nerve trunk" RELATED [] +relationship: part_of MA:0001150 ! vagus X nerve trunk + +[Term] +id: MA:0001153 +name: cervical ganglion +xref: EMAPS:1843828 +is_a: MA:0003100 ! paravertebral ganglion + +[Term] +id: MA:0001154 +name: inferior cervical ganglion +synonym: "stellate ganglion" RELATED [] +xref: EMAPS:1843928 +is_a: MA:0001153 ! cervical ganglion + +[Term] +id: MA:0001155 +name: middle cervical ganglion +xref: EMAPS:1844028 +is_a: MA:0001153 ! cervical ganglion + +[Term] +id: MA:0001156 +name: superior cervical ganglion +xref: EMAPS:1844128 +is_a: MA:0001153 ! cervical ganglion + +[Term] +id: MA:0001157 +name: cervicothoracic ganglion +xref: EMAPS:1822628 +is_a: MA:0003100 ! paravertebral ganglion + +[Term] +id: MA:0001158 +name: celiac ganglion +synonym: "coeliac ganglion" RELATED [] +xref: EMAPS:1932128 +is_a: MA:0003101 ! prevertebral ganglion + +[Term] +id: MA:0001159 +name: thoracic ganglion +xref: EMAPS:1715828 +is_a: MA:0003100 ! paravertebral ganglion + +[Term] +id: MA:0001160 +name: sympathetic nerve plexus +is_a: MA:0002407 ! nerve plexus +relationship: part_of MA:0000225 ! sympathetic nervous system + +[Term] +id: MA:0001161 +name: peripheral nervous system ganglion +xref: EMAPS:3281428 +is_a: MA:0002406 ! ganglion +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0001162 +name: internal carotid nerve plexus +is_a: MA:0001160 ! sympathetic nerve plexus + +[Term] +id: MA:0001163 +name: lumbar sympathetic nerve trunk +is_a: MA:0000227 ! sympathetic nerve trunk + +[Term] +id: MA:0001164 +name: pelvic sympathetic nerve trunk +is_a: MA:0000227 ! sympathetic nerve trunk + +[Term] +id: MA:0001165 +name: thoracic sympathetic nerve trunk +is_a: MA:0000227 ! sympathetic nerve trunk + +[Term] +id: MA:0001166 +name: axillary nerve +xref: EMAPS:1880228 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000595 ! arm nerve +relationship: part_of MA:0001180 ! brachial plexus + +[Term] +id: MA:0001167 +name: femoral nerve +xref: EMAPS:3534328 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000673 ! leg nerve + +[Term] +id: MA:0001168 +name: median nerve +xref: EMAPS:1727728 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000595 ! arm nerve +relationship: part_of MA:0001180 ! brachial plexus + +[Term] +id: MA:0001169 +name: peroneal nerve +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000673 ! leg nerve + +[Term] +id: MA:0001170 +name: phrenic nerve +xref: EMAPS:1781328 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000556 ! thoracic cavity nerve + +[Term] +id: MA:0001171 +name: radial nerve +xref: EMAPS:1727828 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000595 ! arm nerve +relationship: part_of MA:0001180 ! brachial plexus + +[Term] +id: MA:0001172 +name: sciatic nerve +xref: EMAPS:1857728 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000673 ! leg nerve +relationship: part_of MA:0001181 ! lumbosacral plexus + +[Term] +id: MA:0001173 +name: tibial nerve +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000673 ! leg nerve + +[Term] +id: MA:0001174 +name: ulnar nerve +xref: EMAPS:1727928 +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000595 ! arm nerve +relationship: part_of MA:0001180 ! brachial plexus + +[Term] +id: MA:0001175 +name: axillary nerve trunk +synonym: "circumflex nerve trunk" RELATED [] +is_a: MA:0000229 ! peripheral nerve trunk + +[Term] +id: MA:0001176 +name: intercostal nerve trunk +xref: EMAPS:1822728 +is_a: MA:0000229 ! peripheral nerve trunk + +[Term] +id: MA:0001177 +name: phrenic nerve trunk +is_a: MA:0000229 ! peripheral nerve trunk + +[Term] +id: MA:0001178 +name: sciatic nerve trunk +xref: EMAPS:1857728 +is_a: MA:0000229 ! peripheral nerve trunk + +[Term] +id: MA:0001179 +name: segmental spinal nerve trunk +is_a: MA:0000229 ! peripheral nerve trunk + +[Term] +id: MA:0001180 +name: brachial plexus +xref: EMAPS:1698828 +is_a: MA:0000235 ! spinal nerve plexus +is_a: MA:0000616 ! forelimb nerve + +[Term] +id: MA:0001181 +name: lumbosacral plexus +xref: EMAPS:1758728 +is_a: MA:0000235 ! spinal nerve plexus + +[Term] +id: MA:0001182 +name: modiolus +xref: EMAPS:3557528 +relationship: part_of MA:0000239 ! osseus cochlea + +[Term] +id: MA:0001183 +name: osseus cochlear canal +xref: EMAPS:3562128 +relationship: part_of MA:0000239 ! osseus cochlea + +[Term] +id: MA:0001184 +name: osseus spiral lamina +xref: EMAPS:3562228 +relationship: part_of MA:0000239 ! osseus cochlea + +[Term] +id: MA:0001185 +name: osseus labyrinth vestibule +relationship: part_of MA:0000238 ! bony labyrinth + +[Term] +id: MA:0001186 +name: vestibular aqueduct +relationship: part_of MA:0001185 ! osseus labyrinth vestibule + +[Term] +id: MA:0001187 +name: endolymphatic duct +xref: EMAPS:1858028 +relationship: part_of MA:0000241 ! endolymphatic appendage + +[Term] +id: MA:0001188 +name: endolymphatic sac +xref: EMAPS:1759328 +relationship: part_of MA:0000241 ! endolymphatic appendage + +[Term] +id: MA:0001189 +name: inner ear epithelium +xref: EMAPS:3288328 +is_a: MA:0003161 ! ear epithelium +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0001190 +name: basilar membrane +xref: EMAPS:3516628 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001191 +name: limbus lamina spiralis +xref: EMAPS:3549628 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001192 +name: spiral ligament +xref: EMAPS:3579828 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001193 +name: spiral organ +synonym: "organ of corti" RELATED [] +xref: EMAPS:1915128 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001194 +name: reticular lamina +synonym: "reticular membrane" RELATED [] +xref: EMAPS:3573528 +relationship: part_of MA:0001193 ! spiral organ + +[Term] +id: MA:0001195 +name: spiral sulcus +xref: EMAPS:3580028 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001196 +name: external spiral sulcus +xref: EMAPS:3533228 +relationship: part_of MA:0001195 ! spiral sulcus + +[Term] +id: MA:0001197 +name: internal spiral sulcus +xref: EMAPS:3543828 +relationship: part_of MA:0001195 ! spiral sulcus + +[Term] +id: MA:0001198 +name: stria vascularis +xref: EMAPS:3582728 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001199 +name: tectorial membrane +xref: EMAPS:3585128 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001200 +name: vestibular membrane +synonym: "reissner's membrane" RELATED [] +xref: EMAPS:3592228 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0001201 +name: macula of saccule +synonym: "saccular maculs" RELATED [] +xref: EMAPS:3553428 +relationship: part_of MA:0000246 ! saccule + +[Term] +id: MA:0001202 +name: saccule epithelium +xref: EMAPS:1729228 +relationship: part_of MA:0000246 ! saccule + +[Term] +id: MA:0001203 +name: macula of utricle +synonym: "utricular macula" RELATED [] +xref: EMAPS:3553528 +relationship: part_of MA:0000247 ! utricle + +[Term] +id: MA:0001204 +name: utricle epithelium +xref: EMAPS:1729528 +relationship: part_of MA:0000247 ! utricle + +[Term] +id: MA:0001205 +name: scala tympani +xref: EMAPS:3575228 +is_a: MA:0000248 ! perilymphatic channel + +[Term] +id: MA:0001206 +name: scala vestibuli +xref: EMAPS:3575328 +is_a: MA:0000248 ! perilymphatic channel + +[Term] +id: MA:0001207 +name: anterior semicircular canal +is_a: MA:0000250 ! osseus semicircular canal + +[Term] +id: MA:0001208 +name: lateral semicircular canal +xref: EMAPS:1782128 +is_a: MA:0000250 ! osseus semicircular canal + +[Term] +id: MA:0001209 +name: posterior semicircular canal +xref: EMAPS:1729628 +is_a: MA:0000250 ! osseus semicircular canal + +[Term] +id: MA:0001210 +name: crus commune +alt_id: MA:0001212 +synonym: "crus commune" RELATED [] +xref: EMAPS:1781828 +relationship: part_of MA:0000250 ! osseus semicircular canal +relationship: part_of MA:0000251 ! semicircular duct + +[Term] +id: MA:0001211 +name: anterior semicircular duct +is_a: MA:0000251 ! semicircular duct + +[Term] +id: MA:0001213 +name: lateral semicircular duct +is_a: MA:0000251 ! semicircular duct + +[Term] +id: MA:0001214 +name: posterior semicircular duct +is_a: MA:0000251 ! semicircular duct + +[Term] +id: MA:0001215 +name: incus +xref: EMAPS:1858328 +is_a: MA:0000254 ! auditory bone + +[Term] +id: MA:0001216 +name: malleus +xref: EMAPS:1858428 +is_a: MA:0000254 ! auditory bone + +[Term] +id: MA:0001217 +name: stapes +xref: EMAPS:1858528 +is_a: MA:0000254 ! auditory bone + +[Term] +id: MA:0001218 +name: tubotympanic recess +xref: EMAPS:1700228 +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0001219 +name: tympanic cavity blood vessel +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0001220 +name: stapedius +xref: EMAPS:1858628 +is_a: MA:0000256 ! tympanic cavity muscle + +[Term] +id: MA:0001221 +name: tensor tympani +xref: EMAPS:1858728 +is_a: MA:0000256 ! tympanic cavity muscle + +[Term] +id: MA:0001222 +name: tympanic cavity nerves +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0001223 +name: tympanic endothelium +xref: EMAPS:1906328 +relationship: part_of MA:0000257 ! tympanic membrane + +[Term] +id: MA:0001224 +name: tympanic epithelium +xref: EMAPS:1906428 +relationship: part_of MA:0000257 ! tympanic membrane + +[Term] +id: MA:0001225 +name: tympanic ring +xref: EMAPS:1919728 +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0001226 +name: auricular blood vessel +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001227 +name: auricular cartilage +xref: EMAPS:3515828 +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001228 +name: auricular ligament +is_a: MA:0003005 ! skeletal ligament +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001229 +name: auricular muscle +xref: EMAPS:3515928 +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001230 +name: extrinsic auricular muscle +relationship: part_of MA:0001229 ! auricular muscle + +[Term] +id: MA:0001231 +name: intrinsic auricular muscle +relationship: part_of MA:0001229 ! auricular muscle + +[Term] +id: MA:0001232 +name: auricular nerve +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001233 +name: ear skin +xref: EMAPS:3530128 +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0001234 +name: external acoustic meatus cartilaginous part +relationship: part_of MA:0000260 ! external acoustic meatus + +[Term] +id: MA:0001235 +name: external acoustic meatus osseus part +relationship: part_of MA:0000260 ! external acoustic meatus + +[Term] +id: MA:0001236 +name: aqueous humour +xref: EMAPS:1823228 +is_a: MA:0001911 ! ocular refractive media +relationship: part_of MA:0000262 ! eye anterior chamber + +[Term] +id: MA:0001237 +name: choroidal blood vessel +xref: EMAPS:1782828 +relationship: part_of MA:0000263 ! choroid + +[Term] +id: MA:0001238 +name: ciliary epithelium +xref: EMAPS:3523928 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000264 ! ciliary body + +[Term] +id: MA:0001239 +name: ciliary stroma +xref: EMAPS:3524128 +relationship: part_of MA:0000264 ! ciliary body + +[Term] +id: MA:0001240 +name: anterior limiting lamina +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001241 +name: corneal blood vessel +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001242 +name: corneal endothelium +xref: EMAPS:3593528 +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001243 +name: corneal epithelium +xref: EMAPS:1716228 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001244 +name: corneal nerves +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001245 +name: corneal stroma +synonym: "substantia propria" RELATED [] +xref: EMAPS:1760228 +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001246 +name: posterior limiting lamina +relationship: part_of MA:0000266 ! cornea + +[Term] +id: MA:0001247 +name: harderian gland +xref: EMAPS:1915328 +is_a: MA:0000267 ! eye gland + +[Term] +id: MA:0001248 +name: harderian gland epithelium +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0001247 ! harderian gland + +[Term] +id: MA:0001249 +name: meibomian gland +alt_id: MA:0001261 +synonym: "palpebral gland" RELATED [] +synonym: "tarsal gland" RELATED [] +is_a: MA:0002451 ! eye skin gland +is_a: MA:0003043 ! modified sebaceous gland +relationship: part_of MA:0000270 ! eyelid tarsus + +[Term] +id: MA:0001250 +name: eyelid blood vessel +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001251 +name: eyelid connective tissue +xref: EMAPS:3275928 +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001252 +name: eyelid subcutaneous connective tissue +is_a: MA:0001251 ! eyelid connective tissue + +[Term] +id: MA:0001253 +name: eyelid submuscular connective tissue +is_a: MA:0001251 ! eyelid connective tissue + +[Term] +id: MA:0001254 +name: orbicularis oculi +alt_id: MA:0002350 +synonym: "orbicularis oculi" RELATED [] +xref: EMAPS:3561928 +is_a: MA:0000269 ! eyelid muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0001255 +name: eyelid nerve +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001256 +name: eyelid skin +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001257 +name: inferior eyelid tarsus +is_a: MA:0000270 ! eyelid tarsus + +[Term] +id: MA:0001258 +name: medial palpebral ligament +is_a: MA:0003004 ! nonskeletal ligament +relationship: part_of MA:0000270 ! eyelid tarsus + +[Term] +id: MA:0001259 +name: orbital septum +relationship: part_of MA:0000270 ! eyelid tarsus + +[Term] +id: MA:0001260 +name: superior eyelid tarsus +is_a: MA:0000270 ! eyelid tarsus + +[Term] +id: MA:0001262 +name: inner canthus +synonym: "medial canthus" RELATED [] +xref: EMAPS:1783028 +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001263 +name: lower eyelid +xref: EMAPS:1783128 +is_a: MA:0000268 ! eyelid + +[Term] +id: MA:0001264 +name: outer canthus +synonym: "lateral canthus" RELATED [] +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001265 +name: palpebral conjunctiva +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001266 +name: palpebral fissure +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0001267 +name: upper eyelid +xref: EMAPS:1783428 +is_a: MA:0000268 ! eyelid + +[Term] +id: MA:0001268 +name: ocular smooth muscle +xref: EMAPS:1880728 +is_a: MA:0000271 ! eye muscle + +[Term] +id: MA:0001269 +name: ciliary muscle +xref: EMAPS:3524028 +is_a: MA:0001268 ! ocular smooth muscle + +[Term] +id: MA:0001270 +name: iris smooth muscle +xref: EMAPS:3545028 +is_a: MA:0001268 ! ocular smooth muscle +relationship: part_of MA:0001287 ! iris muscle + +[Term] +id: MA:0001271 +name: extraocular skeletal muscle +xref: EMAPS:1823428 +is_a: MA:0000271 ! eye muscle + +[Term] +id: MA:0001272 +name: levator palpebrae superioris +is_a: MA:0000269 ! eyelid muscle + +[Term] +id: MA:0001273 +name: biliary tract +xref: EMAPS:3517228 +relationship: part_of MA:0000324 ! hepatobiliary system + +[Term] +id: MA:0001274 +name: orbitalis muscle +is_a: MA:0000269 ! eyelid muscle + +[Term] +id: MA:0001275 +name: oblique extraocular muscle +is_a: MA:0002432 ! oculomotor muscle + +[Term] +id: MA:0001276 +name: inferior oblique extraocular muscle +is_a: MA:0001275 ! oblique extraocular muscle + +[Term] +id: MA:0001277 +name: superior oblique extraocular muscle +is_a: MA:0001275 ! oblique extraocular muscle + +[Term] +id: MA:0001278 +name: rectus extraocular muscle +is_a: MA:0002432 ! oculomotor muscle + +[Term] +id: MA:0001279 +name: inferior rectus extraocular muscle +is_a: MA:0001278 ! rectus extraocular muscle + +[Term] +id: MA:0001280 +name: lateral rectus extraocular muscle +is_a: MA:0001278 ! rectus extraocular muscle + +[Term] +id: MA:0001281 +name: medial rectus extraocular muscle +is_a: MA:0001278 ! rectus extraocular muscle + +[Term] +id: MA:0001282 +name: superior rectus extraocular muscle +is_a: MA:0001278 ! rectus extraocular muscle + +[Term] +id: MA:0001283 +name: hyaloid vascular plexus +xref: EMAPS:1730328 +relationship: part_of MA:0000272 ! hyaloid cavity + +[Term] +id: MA:0001284 +name: tunica vasculosa plexus +xref: EMAPS:1823528 +is_a: MA:0001283 ! hyaloid vascular plexus + +[Term] +id: MA:0001285 +name: vasa hyaloidea propria +xref: EMAPS:1823628 +is_a: MA:0001283 ! hyaloid vascular plexus + +[Term] +id: MA:0001286 +name: vitreous humor +synonym: "vitreous humour" RELATED [] +xref: EMAPS:1783728 +is_a: MA:0001911 ! ocular refractive media +relationship: part_of MA:0000272 ! hyaloid cavity +relationship: part_of MA:0002462 ! vitreous body + +[Term] +id: MA:0001287 +name: iris muscle +xref: EMAPS:3544828 +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0001288 +name: dilatator pupillae +xref: EMAPS:3528628 +is_a: MA:0001287 ! iris muscle + +[Term] +id: MA:0001289 +name: sphincter pupillae +xref: EMAPS:3578828 +is_a: MA:0001287 ! iris muscle + +[Term] +id: MA:0001290 +name: iris blood vessel +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0001291 +name: iris nerve +xref: EMAPS:3544928 +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0001292 +name: pupil +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0001293 +name: pupillary membrane +relationship: part_of MA:0001292 ! pupil + +[Term] +id: MA:0001294 +name: lacrimal canaliculus +relationship: part_of MA:0000274 ! lacrimal apparatus + +[Term] +id: MA:0001295 +name: lacrimal duct +synonym: "tear duct" RELATED [] +relationship: part_of MA:0000274 ! lacrimal apparatus + +[Term] +id: MA:0001296 +name: lacrimal gland +xref: EMAPS:3546328 +is_a: MA:0000267 ! eye gland +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0000274 ! lacrimal apparatus + +[Term] +id: MA:0001297 +name: lacrimal gland epithelium +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0001296 ! lacrimal gland + +[Term] +id: MA:0001298 +name: lacrimal sac +relationship: part_of MA:0000274 ! lacrimal apparatus + +[Term] +id: MA:0001299 +name: nasolacrimal duct +xref: EMAPS:1785328 +relationship: part_of MA:0000274 ! lacrimal apparatus + +[Term] +id: MA:0001300 +name: lens capsule +xref: EMAPS:1823728 +relationship: part_of MA:0000275 ! lens + +[Term] +id: MA:0001301 +name: lens epithelium +xref: EMAPS:3287128 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000275 ! lens + +[Term] +id: MA:0001302 +name: lens anterior epithelium +xref: EMAPS:1783928 +is_a: MA:0001301 ! lens epithelium + +[Term] +id: MA:0001303 +name: lens equatorial epithelium +xref: EMAPS:1784028 +is_a: MA:0001301 ! lens epithelium + +[Term] +id: MA:0001304 +name: lens fiber +xref: EMAPS:1784128 +relationship: part_of MA:0000275 ! lens + +[Term] +id: MA:0001305 +name: choroid fissure +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001306 +name: macula +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001307 +name: fovea +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001308 +name: retina photoreceptor layer +synonym: "layer of rods and cones" RELATED [] +xref: EMAPS:3568628 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001309 +name: retina external limiting lamina +is_a: MA:0001318 ! retina lamina + +[Term] +id: MA:0001310 +name: retina ganglion cell layer +xref: EMAPS:3573928 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001311 +name: retina inner nuclear layer +xref: EMAPS:1915528 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001312 +name: retina inner plexiform layer +xref: EMAPS:3574128 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001313 +name: retina internal limiting lamina +is_a: MA:0001318 ! retina lamina + +[Term] +id: MA:0001314 +name: retina nerve fiber layer +xref: EMAPS:1859128 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001315 +name: retina outer nuclear layer +xref: EMAPS:1915728 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001316 +name: retina outer plexiform layer +xref: EMAPS:3574428 +is_a: MA:0001319 ! retina layer + +[Term] +id: MA:0001317 +name: retina blood vessel +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001318 +name: retina lamina +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001319 +name: retina layer +xref: EMAPS:3574228 +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0001320 +name: external naris +xref: EMAPS:1784828 +is_a: MA:0000282 ! naris + +[Term] +id: MA:0001321 +name: external naris epithelium +xref: EMAPS:1859628 +relationship: part_of MA:0001320 ! external naris + +[Term] +id: MA:0001322 +name: primary choana +xref: EMAPS:1785128 +relationship: part_of MA:0001320 ! external naris + +[Term] +id: MA:0001323 +name: internal naris +is_a: MA:0000282 ! naris + +[Term] +id: MA:0001324 +name: nasal cavity epithelium +synonym: "nasal mucosa" RELATED [] +xref: EMAPS:1760528 +is_a: MA:0001912 ! upper respiratory tract epithelium +is_a: MA:0003171 ! nose epithelium +relationship: part_of MA:0000284 ! nasal cavity + +[Term] +id: MA:0001325 +name: nasal cavity olfactory epithelium +synonym: "olfactory mucosa" RELATED [] +xref: EMAPS:1760628 +is_a: MA:0001324 ! nasal cavity epithelium + +[Term] +id: MA:0001326 +name: nasal cavity respiratory epithelium +xref: EMAPS:1760728 +is_a: MA:0001324 ! nasal cavity epithelium + +[Term] +id: MA:0001327 +name: septal olfactory organ +xref: EMAPS:3576428 +relationship: part_of MA:0000285 ! nasal septum + +[Term] +id: MA:0001328 +name: vomeronasal organ sensory epithelium +is_a: MA:0003171 ! nose epithelium +relationship: part_of MA:0000289 ! vomeronasal organ + +[Term] +id: MA:0001329 +name: clavicle +xref: EMAPS:1872128 +is_a: MA:0000292 ! pectoral girdle bone +is_a: MA:0000631 ! shoulder bone + +[Term] +id: MA:0001330 +name: scapula +xref: EMAPS:1872228 +is_a: MA:0000292 ! pectoral girdle bone +is_a: MA:0000631 ! shoulder bone + +[Term] +id: MA:0001331 +name: sternum +xref: EMAPS:1834428 +is_a: MA:0000292 ! pectoral girdle bone + +[Term] +id: MA:0001332 +name: sternal manubrium +xref: EMAPS:1872328 +relationship: part_of MA:0001331 ! sternum + +[Term] +id: MA:0001333 +name: sternebra +xref: EMAPS:1872428 +relationship: part_of MA:0001331 ! sternum + +[Term] +id: MA:0001334 +name: xiphisternum +xref: EMAPS:1872528 +relationship: part_of MA:0001331 ! sternum + +[Term] +id: MA:0001335 +name: acetabulum +xref: EMAPS:1834628 +is_a: MA:0000293 ! pelvic girdle bone + +[Term] +id: MA:0001336 +name: ilium +xref: EMAPS:1872628 +is_a: MA:0000293 ! pelvic girdle bone +is_a: MA:0000655 ! hip bone + +[Term] +id: MA:0001337 +name: ischium +xref: EMAPS:1872728 +is_a: MA:0000293 ! pelvic girdle bone +is_a: MA:0000655 ! hip bone + +[Term] +id: MA:0001338 +name: pubis +xref: EMAPS:3571728 +is_a: MA:0000293 ! pelvic girdle bone +is_a: MA:0000655 ! hip bone + +[Term] +id: MA:0001339 +name: pisiform +synonym: "accessory carpal bone" RELATED [] +is_a: MA:0002557 ! proximal carpal bone + +[Term] +id: MA:0001340 +name: trapezium +synonym: "greater multiangular" RELATED [] +synonym: "hand distal carpal bone 1" RELATED [] +is_a: MA:0002558 ! distal carpal bone + +[Term] +id: MA:0001341 +name: trapezoid +synonym: "hand distal carpal bone 2" RELATED [] +synonym: "lesser multiangular" RELATED [] +is_a: MA:0002558 ! distal carpal bone + +[Term] +id: MA:0001342 +name: capitate +synonym: "hand distal carpal bone 3" RELATED [] +is_a: MA:0002558 ! distal carpal bone + +[Term] +id: MA:0001343 +name: hamate +synonym: "hand distal carpal bone 4" RELATED [] +synonym: "unciform" RELATED [] +synonym: "uncinate" RELATED [] +is_a: MA:0002558 ! distal carpal bone + +[Term] +id: MA:0001344 +name: central carpal bone +synonym: "centrale" RELATED [] +is_a: MA:0000296 ! carpal bone + +[Term] +id: MA:0001345 +name: falciform carpal bone +is_a: MA:0000296 ! carpal bone + +[Term] +id: MA:0001346 +name: scapholunate +synonym: "intermedioradial carpal bone" RELATED [] +is_a: MA:0002557 ! proximal carpal bone + +[Term] +id: MA:0001347 +name: triquetral +synonym: "cuneiform of hand" RELATED [] +synonym: "triangular" RELATED [] +synonym: "triquetrum" RELATED [] +synonym: "ulnar carpal bone" RELATED [] +is_a: MA:0002557 ! proximal carpal bone + +[Term] +id: MA:0001348 +name: calcaneum +synonym: "calcaneus" RELATED [] +synonym: "fibulare" RELATED [] +xref: EMAPS:1913428 +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001349 +name: navicular +synonym: "central tarsal bone" RELATED [] +synonym: "centrale" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001350 +name: medial tibial tarsal bone +synonym: "tibiale" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001351 +name: talus +synonym: "astragalus" RELATED [] +xref: EMAPS:1913528 +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001352 +name: medial cuneiform +synonym: "foot distal carpal bone 1" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001353 +name: intermediate cuneiform +synonym: "foot distal carpal bone 2" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001354 +name: lateral cuneiform +synonym: "foor distal carpal bone 3" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001355 +name: cuboid +synonym: "foot distal carpal bone 4 and 5" RELATED [] +is_a: MA:0000297 ! tarsal bone + +[Term] +id: MA:0001356 +name: humerus +xref: EMAPS:1910628 +is_a: MA:0000299 ! forelimb long bone +is_a: MA:0000604 ! upper arm bone +is_a: MA:0000631 ! shoulder bone + +[Term] +id: MA:0001357 +name: radius +xref: EMAPS:1910328 +is_a: MA:0000299 ! forelimb long bone +is_a: MA:0000598 ! lower arm bone + +[Term] +id: MA:0001358 +name: ulna +xref: EMAPS:1910428 +is_a: MA:0000299 ! forelimb long bone +is_a: MA:0000598 ! lower arm bone + +[Term] +id: MA:0001359 +name: femur +xref: EMAPS:1914328 +is_a: MA:0000300 ! hindlimb long bone +is_a: MA:0000655 ! hip bone +is_a: MA:0000682 ! upper leg bone + +[Term] +id: MA:0001360 +name: fibula +xref: EMAPS:1914128 +is_a: MA:0000300 ! hindlimb long bone +is_a: MA:0000676 ! lower leg bone + +[Term] +id: MA:0001361 +name: tibia +xref: EMAPS:1914228 +is_a: MA:0000300 ! hindlimb long bone +is_a: MA:0000676 ! lower leg bone + +[Term] +id: MA:0001362 +name: long bone epiphysis +xref: EMAPS:3550828 +relationship: part_of MA:0002802 ! long bone + +[Term] +id: MA:0001363 +name: long bone metaphysis +xref: EMAPS:3550928 +relationship: part_of MA:0000298 ! limb long bone +relationship: part_of MA:0002802 ! long bone + +[Term] +id: MA:0001364 +name: metacarpal bone digit 1 +xref: EMAPS:1911228 +is_a: MA:0000302 ! metacarpal bone + +[Term] +id: MA:0001365 +name: metacarpal bone digit 2 +xref: EMAPS:1911428 +is_a: MA:0000302 ! metacarpal bone + +[Term] +id: MA:0001366 +name: metacarpal bone digit 3 +xref: EMAPS:1911628 +is_a: MA:0000302 ! metacarpal bone + +[Term] +id: MA:0001367 +name: metacarpal bone digit 4 +xref: EMAPS:1911828 +is_a: MA:0000302 ! metacarpal bone + +[Term] +id: MA:0001368 +name: metacarpal bone digit 5 +xref: EMAPS:1912028 +is_a: MA:0000302 ! metacarpal bone + +[Term] +id: MA:0001369 +name: metatarsal bone digit 1 +xref: EMAPS:1912328 +is_a: MA:0000303 ! metatarsal bone + +[Term] +id: MA:0001370 +name: metatarsal bone digit 2 +xref: EMAPS:1912528 +is_a: MA:0000303 ! metatarsal bone + +[Term] +id: MA:0001371 +name: metatarsal bone digit 3 +xref: EMAPS:1912728 +is_a: MA:0000303 ! metatarsal bone + +[Term] +id: MA:0001372 +name: metatarsal bone digit 4 +xref: EMAPS:1912928 +is_a: MA:0000303 ! metatarsal bone + +[Term] +id: MA:0001373 +name: metatarsal bone digit 5 +xref: EMAPS:1913128 +is_a: MA:0000303 ! metatarsal bone + +[Term] +id: MA:0001374 +name: patella +xref: EMAPS:3566828 +is_a: MA:0000666 ! knee bone +is_a: MA:0001375 ! sesamoid bone + +[Term] +id: MA:0001375 +name: sesamoid bone +is_a: MA:0000307 ! other limb bone + +[Term] +id: MA:0001376 +name: proximal sesamoid bone of foot +is_a: MA:0000646 ! foot digit bone +is_a: MA:0001375 ! sesamoid bone + +[Term] +id: MA:0001377 +name: proximal sesamoid bone of hand +is_a: MA:0000622 ! hand digit bone +is_a: MA:0001375 ! sesamoid bone + +[Term] +id: MA:0001378 +name: sesamoid bone of gastrocnemius +synonym: "fabella" RELATED [] +xref: EMAPS:3577128 +is_a: MA:0000676 ! lower leg bone +is_a: MA:0001375 ! sesamoid bone + +[Term] +id: MA:0001379 +name: ulnar sesamoid bone +is_a: MA:0000598 ! lower arm bone +is_a: MA:0001375 ! sesamoid bone + +[Term] +id: MA:0001380 +name: foot distal phalanx +is_a: MA:0000305 ! foot phalanx +is_a: MA:0002914 ! distal phalanx + +[Term] +id: MA:0001381 +name: foot digit 1 phalanx +xref: EMAPS:1912428 +is_a: MA:0000305 ! foot phalanx + +[Term] +id: MA:0001382 +name: foot digit 2 phalanx +xref: EMAPS:1912628 +is_a: MA:0000305 ! foot phalanx + +[Term] +id: MA:0001383 +name: foot digit 3 phalanx +xref: EMAPS:1912828 +is_a: MA:0000305 ! foot phalanx + +[Term] +id: MA:0001384 +name: foot digit 4 phalanx +xref: EMAPS:1913028 +is_a: MA:0000305 ! foot phalanx + +[Term] +id: MA:0001385 +name: foot digit 5 phalanx +xref: EMAPS:1913228 +is_a: MA:0000305 ! foot phalanx + +[Term] +id: MA:0001386 +name: foot middle phalanx +is_a: MA:0000305 ! foot phalanx +is_a: MA:0002915 ! middle phalanx + +[Term] +id: MA:0001387 +name: foot proximal phalanx +is_a: MA:0000305 ! foot phalanx +is_a: MA:0002916 ! proximal phalanx + +[Term] +id: MA:0001388 +name: hand distal phalanx +xref: EMAPS:3539328 +is_a: MA:0000306 ! hand phalanx +is_a: MA:0002914 ! distal phalanx + +[Term] +id: MA:0001389 +name: hand digit 1 phalanx +xref: EMAPS:1911328 +is_a: MA:0000306 ! hand phalanx + +[Term] +id: MA:0001390 +name: hand digit 2 phalanx +xref: EMAPS:1911528 +is_a: MA:0000306 ! hand phalanx + +[Term] +id: MA:0001391 +name: hand digit 3 phalanx +xref: EMAPS:1911728 +is_a: MA:0000306 ! hand phalanx + +[Term] +id: MA:0001392 +name: hand digit 4 phalanx +xref: EMAPS:1911928 +is_a: MA:0000306 ! hand phalanx + +[Term] +id: MA:0001393 +name: hand digit 5 phalanx +xref: EMAPS:1912128 +is_a: MA:0000306 ! hand phalanx + +[Term] +id: MA:0001394 +name: hand middle phalanx +is_a: MA:0000306 ! hand phalanx +is_a: MA:0002915 ! middle phalanx + +[Term] +id: MA:0001395 +name: hand proximal phalanx +is_a: MA:0000306 ! hand phalanx +is_a: MA:0002916 ! proximal phalanx + +[Term] +id: MA:0001396 +name: costal arch +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001397 +name: distal rib +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001398 +name: false rib +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001399 +name: floating rib +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001400 +name: proximal rib +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001401 +name: rib 1 +xref: EMAPS:1952928 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001402 +name: rib 2 +xref: EMAPS:1953028 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001403 +name: rib 3 +xref: EMAPS:1953128 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001404 +name: rib 4 +xref: EMAPS:1953228 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001405 +name: rib 5 +xref: EMAPS:1953328 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001406 +name: rib 6 +xref: EMAPS:1953428 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001407 +name: rib 7 +xref: EMAPS:1953528 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001408 +name: rib 8 +xref: EMAPS:1953628 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001409 +name: rib 9 +xref: EMAPS:1953728 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001410 +name: rib 10 +xref: EMAPS:1953828 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001411 +name: rib 11 +xref: EMAPS:1953928 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001412 +name: rib 12 +xref: EMAPS:1954028 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001413 +name: rib 13 +xref: EMAPS:1954128 +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001414 +name: rib dorsal segment +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001415 +name: rib head +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001416 +name: rib shaft +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001417 +name: rib tubercle +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001418 +name: rib ventral segment +relationship: part_of MA:0000315 ! rib + +[Term] +id: MA:0001419 +name: true rib +is_a: MA:0000315 ! rib + +[Term] +id: MA:0001420 +name: coccygeal vertebra +synonym: "coccygea" RELATED [] +is_a: MA:0000310 ! caudal vertebra + +[Term] +id: MA:0001421 +name: cervical vertebra 1 +synonym: "atlas" RELATED [] +xref: EMAPS:1943128 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001422 +name: cervical vertebra 2 +synonym: "axis" RELATED [] +xref: EMAPS:1943228 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001423 +name: cervical vertebra 3 +xref: EMAPS:1943328 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001424 +name: cervical vertebra 4 +xref: EMAPS:1943428 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001425 +name: cervical vertebra 5 +xref: EMAPS:1943528 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001426 +name: cervical vertebra 6 +xref: EMAPS:1946628 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001427 +name: cervical vertebra 7 +xref: EMAPS:1946728 +is_a: MA:0000311 ! cervical vertebra + +[Term] +id: MA:0001428 +name: lumbar vertebra 1 +xref: EMAPS:1947228 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001429 +name: lumbar vertebra 2 +xref: EMAPS:1957028 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001430 +name: lumbar vertebra 3 +xref: EMAPS:1957128 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001431 +name: lumbar vertebra 4 +xref: EMAPS:1957228 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001432 +name: lumbar vertebra 5 +xref: EMAPS:1957328 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001433 +name: lumbar vertebra 6 +xref: EMAPS:1957428 +is_a: MA:0000312 ! lumbar vertebra + +[Term] +id: MA:0001434 +name: sacral vertebra 1 +xref: EMAPS:1958828 +is_a: MA:0000313 ! sacral vertebra + +[Term] +id: MA:0001435 +name: sacral vertebra 2 +xref: EMAPS:1958928 +is_a: MA:0000313 ! sacral vertebra + +[Term] +id: MA:0001436 +name: sacral vertebra 3 +xref: EMAPS:1959028 +is_a: MA:0000313 ! sacral vertebra + +[Term] +id: MA:0001437 +name: sacral vertebra 4 +xref: EMAPS:1959128 +is_a: MA:0000313 ! sacral vertebra + +[Term] +id: MA:0001438 +name: thoracic vertebra 1 +xref: EMAPS:1954228 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001439 +name: thoracic vertebra 2 +xref: EMAPS:1954328 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001440 +name: thoracic vertebra 3 +xref: EMAPS:1954428 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001441 +name: thoracic vertebra 4 +xref: EMAPS:1954528 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001442 +name: thoracic vertebra 5 +xref: EMAPS:1954628 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001443 +name: thoracic vertebra 6 +xref: EMAPS:1954728 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001444 +name: thoracic vertebra 7 +xref: EMAPS:1954828 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001445 +name: thoracic vertebra 8 +xref: EMAPS:1954928 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001446 +name: thoracic vertebra 9 +xref: EMAPS:1955028 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001447 +name: thoracic vertebra 10 +xref: EMAPS:1955128 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001448 +name: thoracic vertebra 11 +xref: EMAPS:1955228 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001449 +name: thoracic vertebra 12 +xref: EMAPS:1955328 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001450 +name: thoracic vertebra 13 +xref: EMAPS:1955428 +is_a: MA:0000314 ! thoracic vertebra + +[Term] +id: MA:0001451 +name: vertebra caudal articular process +synonym: "postzygapophysis" RELATED [] +xref: EMAPS:3591828 +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001452 +name: vertebra cranial articular process +synonym: "prezygapophysis" RELATED [] +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001453 +name: vertebra arch +synonym: "vertebra dorsal arch" RELATED [] +synonym: "vertebra neural arch" RELATED [] +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001454 +name: vertebra neural canal +synonym: "vertebral foramen" RELATED [] +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001455 +name: vertebra spinous process +synonym: "neural spine" RELATED [] +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001456 +name: vertebra transverse process +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001457 +name: vertebral body +synonym: "vertebral centrum" RELATED [] +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001458 +name: vertebral pedicle +relationship: part_of MA:0000309 ! vertebra + +[Term] +id: MA:0001459 +name: bone +synonym: "bone organ" RELATED [] +xref: EMAPS:3278228 +relationship: part_of MA:0003006 ! skeleton + +[Term] +id: MA:0001460 +name: ovary stratum granulosum +xref: EMAPS:3563328 +relationship: part_of MA:0001707 ! ovary follicle + +[Term] +id: MA:0001461 +name: compact bone +synonym: "cortical bone" RELATED [] +xref: EMAPS:3525028 +is_a: MA:0002780 ! bone tissue +relationship: part_of MA:0002781 ! lamellar bone + +[Term] +id: MA:0001462 +name: basioccipital bone +xref: EMAPS:1870528 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001463 +name: basisphenoid bone +xref: EMAPS:1870628 +is_a: MA:0001478 ! chondrocranium bone +relationship: part_of MA:0001472 ! sphenoid bone + +[Term] +id: MA:0001464 +name: exoccipital bone +xref: EMAPS:1870828 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001465 +name: fontanel +relationship: part_of MA:0000317 ! chondrocranium + +[Term] +id: MA:0001466 +name: frontal bone +xref: EMAPS:1901628 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001467 +name: interparietal bone +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001468 +name: occipital bone +xref: EMAPS:2511228 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001469 +name: parietal bone +xref: EMAPS:1871528 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001470 +name: presphenoid bone +is_a: MA:0001478 ! chondrocranium bone +relationship: part_of MA:0001472 ! sphenoid bone + +[Term] +id: MA:0001471 +name: pterygoid bone +synonym: "inner plate of pterygoid process" RELATED [] +is_a: MA:0001478 ! chondrocranium bone +relationship: part_of MA:0002774 ! sphenoid bone pterygoid process + +[Term] +id: MA:0001472 +name: sphenoid bone +xref: EMAPS:1834028 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001473 +name: squamosal bone +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001474 +name: supraoccipital bone +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001475 +name: cranial suture +xref: EMAPS:3526328 +is_a: MA:0000321 ! fibrous joint +relationship: part_of MA:0000317 ! chondrocranium + +[Term] +id: MA:0001476 +name: temporal bone +xref: EMAPS:1768228 +is_a: MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0001477 +name: temporal bone petrous part +xref: EMAPS:1768328 +relationship: part_of MA:0001476 ! temporal bone + +[Term] +id: MA:0001478 +name: chondrocranium bone +xref: EMAPS:3523828 +is_a: MA:0001459 ! bone +relationship: part_of MA:0000317 ! chondrocranium + +[Term] +id: MA:0001480 +name: respiratory tract epithelium +xref: EMAPS:3282728 +is_a: MA:0001823 ! respiratory system epithelium +relationship: part_of MA:0000434 ! respiratory tract + +[Term] +id: MA:0001481 +name: lower respiratory tract epithelium +is_a: MA:0001480 ! respiratory tract epithelium +relationship: part_of MA:0000435 ! lower respiratory tract + +[Term] +id: MA:0001482 +name: viscerocranium bone +xref: EMAPS:3592428 +relationship: part_of MA:0000318 ! viscerocranium + +[Term] +id: MA:0001483 +name: ethmoid bone +xref: EMAPS:1901828 +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001484 +name: hyoid bone +xref: EMAPS:1865028 +is_a: MA:0001482 ! viscerocranium bone +relationship: part_of MA:0003037 ! hyoid apparatus + +[Term] +id: MA:0001486 +name: lacrimal bone +synonym: "lacrymal bone" RELATED [] +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001487 +name: mandible +xref: EMAPS:1829028 +is_a: MA:0000345 ! oral region cartilage/bone +is_a: MA:0001482 ! viscerocranium bone +is_a: MA:0003130 ! jaw bone +relationship: part_of MA:0001906 ! lower jaw + +[Term] +id: MA:0001488 +name: mandible petrous part +relationship: part_of MA:0001487 ! mandible + +[Term] +id: MA:0001489 +name: mandible squamous part +relationship: part_of MA:0001487 ! mandible + +[Term] +id: MA:0001490 +name: symphysis menti +relationship: part_of MA:0001487 ! mandible + +[Term] +id: MA:0001491 +name: maxilla +xref: EMAPS:1763928 +is_a: MA:0000345 ! oral region cartilage/bone +is_a: MA:0001482 ! viscerocranium bone +is_a: MA:0003130 ! jaw bone +relationship: part_of MA:0001908 ! upper jaw + +[Term] +id: MA:0001492 +name: maxilla alveolar process +relationship: part_of MA:0001491 ! maxilla + +[Term] +id: MA:0001493 +name: premaxilla +alt_id: MA:0001485 +synonym: "incisive bone" EXACT [] +xref: EMAPS:1764128 +is_a: MA:0000345 ! oral region cartilage/bone +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001494 +name: nasal bone +xref: EMAPS:1920228 +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001495 +name: palatine bone +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001496 +name: vomer bone +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001497 +name: zygomatic bone +xref: EMAPS:2511128 +is_a: MA:0001478 ! chondrocranium bone +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0001498 +name: cartilaginous joint suture +relationship: part_of MA:0000320 ! cartilaginous joint + +[Term] +id: MA:0001499 +name: gomphosis +is_a: MA:0000320 ! cartilaginous joint + +[Term] +id: MA:0001500 +name: syndesmosis +is_a: MA:0000320 ! cartilaginous joint + +[Term] +id: MA:0001501 +name: synchondrosis +xref: EMAPS:3584628 +is_a: MA:0000321 ! fibrous joint + +[Term] +id: MA:0001502 +name: cranial synchondrosis +xref: EMAPS:3526428 +is_a: MA:0001501 ! synchondrosis + +[Term] +id: MA:0001503 +name: postcranial synchondrosis +is_a: MA:0001501 ! synchondrosis + +[Term] +id: MA:0001504 +name: symphysis +is_a: MA:0000321 ! fibrous joint + +[Term] +id: MA:0001505 +name: joint of girdle +is_a: MA:0000319 ! joint + +[Term] +id: MA:0001506 +name: sacroiliac joint +xref: EMAPS:1930028 +is_a: MA:0001505 ! joint of girdle + +[Term] +id: MA:0001507 +name: sternoclavicular joint +xref: EMAPS:1920328 +is_a: MA:0001505 ! joint of girdle + +[Term] +id: MA:0001508 +name: joint of rib +is_a: MA:0000319 ! joint + +[Term] +id: MA:0001509 +name: costochondral joint +is_a: MA:0001508 ! joint of rib + +[Term] +id: MA:0001510 +name: costovertebral joint +xref: EMAPS:1902028 +is_a: MA:0001508 ! joint of rib + +[Term] +id: MA:0001511 +name: interchondral joint +is_a: MA:0001508 ! joint of rib + +[Term] +id: MA:0001512 +name: sternocostal joint +is_a: MA:0001508 ! joint of rib + +[Term] +id: MA:0001513 +name: joint of vertebral arch +is_a: MA:0000319 ! joint + +[Term] +id: MA:0001514 +name: joint of vertebral body +is_a: MA:0000319 ! joint + +[Term] +id: MA:0001518 +name: joint articular surface +relationship: part_of MA:0000322 ! synovial joint + +[Term] +id: MA:0001519 +name: joint fibrous capsule +relationship: part_of MA:0000322 ! synovial joint + +[Term] +id: MA:0001520 +name: gastrointestinal system epithelium +xref: EMAPS:3268328 +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001521 +name: gastrointestinal system mucosa +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001522 +name: gastrointestinal system serosa +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001523 +name: gastrointestinal system smooth muscle +xref: EMAPS:3511728 +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001524 +name: bowel +xref: EMAPS:3518028 +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001525 +name: bowel wall +xref: EMAPS:3518128 +relationship: part_of MA:0001524 ! bowel + +[Term] +id: MA:0001526 +name: foregut +xref: EMAPS:1654828 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0001527 +name: hindgut +xref: EMAPS:1671528 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0001528 +name: anal canal caudal part +xref: EMAPS:1826128 +relationship: part_of MA:0000330 ! anal canal + +[Term] +id: MA:0001529 +name: anal canal rostral part +xref: EMAPS:1825728 +relationship: part_of MA:0000330 ! anal canal + +[Term] +id: MA:0001530 +name: anal region skeletal muscle +relationship: part_of MA:0000329 ! anal region + +[Term] +id: MA:0001531 +name: external anal sphincter +alt_id: MA:0002379 +synonym: "sphincter ani externus" RELATED [] +xref: EMAPS:1826528 +is_a: MA:0001530 ! anal region skeletal muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0001532 +name: anal region smooth muscle +relationship: part_of MA:0000329 ! anal region + +[Term] +id: MA:0001533 +name: anococcygeus +is_a: MA:0001532 ! anal region smooth muscle + +[Term] +id: MA:0001534 +name: internal anal sphincter +xref: EMAPS:1826628 +is_a: MA:0001532 ! anal region smooth muscle + +[Term] +id: MA:0001535 +name: crypt of lieberkuhn +xref: EMAPS:3526628 +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0001536 +name: intestine epithelium +xref: EMAPS:3287328 +is_a: MA:0001520 ! gastrointestinal system epithelium +relationship: part_of MA:0001537 ! intestine mucosa + +[Term] +id: MA:0001537 +name: intestine mucosa +xref: EMAPS:3544028 +is_a: MA:0001521 ! gastrointestinal system mucosa +relationship: part_of MA:0002693 ! intestine wall + +[Term] +id: MA:0001538 +name: intestine serosa +is_a: MA:0001522 ! gastrointestinal system serosa +relationship: part_of MA:0002693 ! intestine wall + +[Term] +id: MA:0001539 +name: intestine smooth muscle +xref: EMAPS:3544128 +xref: EMAPS:3544328 +is_a: MA:0001523 ! gastrointestinal system smooth muscle +relationship: part_of MA:0002693 ! intestine wall + +[Term] +id: MA:0001540 +name: appendix +synonym: "apex of cecum" RELATED [] +xref: EMAPS:3514028 +relationship: part_of MA:0000334 ! cecum + +[Term] +id: MA:0001541 +name: ascending colon +xref: EMAPS:3515128 +is_a: MA:0000335 ! colon + +[Term] +id: MA:0001542 +name: descending colon +xref: EMAPS:3528528 +is_a: MA:0000335 ! colon + +[Term] +id: MA:0001543 +name: transverse colon +xref: EMAPS:3588028 +is_a: MA:0000335 ! colon + +[Term] +id: MA:0001544 +name: large intestine crypt of lieberkuhn +xref: EMAPS:3546528 +is_a: MA:0001535 ! crypt of lieberkuhn +relationship: part_of MA:0000333 ! large intestine + +[Term] +id: MA:0001545 +name: large intestine epithelium +xref: EMAPS:3546628 +is_a: MA:0001536 ! intestine epithelium +relationship: part_of MA:0002688 ! large intestine mucosa + +[Term] +id: MA:0001546 +name: large intestine serosa +relationship: part_of MA:0001538 ! intestine serosa +relationship: part_of MA:0002695 ! large intestine wall + +[Term] +id: MA:0001547 +name: large intestine smooth muscle +xref: EMAPS:3546928 +relationship: part_of MA:0001539 ! intestine smooth muscle +relationship: part_of MA:0002695 ! large intestine wall + +[Term] +id: MA:0001548 +name: large intestine smooth muscle circular layer +relationship: part_of MA:0001547 ! large intestine smooth muscle + +[Term] +id: MA:0001549 +name: large intestine smooth muscle longitudinal layer +relationship: part_of MA:0001547 ! large intestine smooth muscle + +[Term] +id: MA:0001550 +name: large intestine peyer's patch +xref: EMAPS:3546828 +is_a: MA:0000137 ! peyer's patch +relationship: part_of MA:0000333 ! large intestine + +[Term] +id: MA:0001551 +name: brunner's gland +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0001552 +name: small intestine crypt of lieberkuhn +xref: EMAPS:3577728 +is_a: MA:0001535 ! crypt of lieberkuhn +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0001553 +name: small intestine epithelium +xref: EMAPS:3577828 +is_a: MA:0001536 ! intestine epithelium +relationship: part_of MA:0002686 ! small intestine mucosa + +[Term] +id: MA:0001554 +name: small intestine lamina propria +xref: EMAPS:3577928 +is_a: MA:0001899 ! gastrointestinal system lamina propria +relationship: part_of MA:0002686 ! small intestine mucosa + +[Term] +id: MA:0001555 +name: small intestine mesentery +is_a: MA:0001900 ! gastrointestinal system mesentery +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0001556 +name: mesoduodenum +xref: EMAPS:1908228 +is_a: MA:0001555 ! small intestine mesentery + +[Term] +id: MA:0001557 +name: small intestine peyer's patch +xref: EMAPS:3578228 +is_a: MA:0000137 ! peyer's patch +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0001558 +name: small intestine serosa +relationship: part_of MA:0001538 ! intestine serosa +relationship: part_of MA:0002696 ! small intestine wall + +[Term] +id: MA:0001559 +name: small intestine smooth muscle +xref: EMAPS:3578328 +relationship: part_of MA:0001539 ! intestine smooth muscle +relationship: part_of MA:0002696 ! small intestine wall + +[Term] +id: MA:0001560 +name: small intestine smooth muscle circular layer +relationship: part_of MA:0001559 ! small intestine smooth muscle + +[Term] +id: MA:0001561 +name: small intestine smooth muscle longitudinal layer +relationship: part_of MA:0001559 ! small intestine smooth muscle + +[Term] +id: MA:0001562 +name: small intestine submucosa +relationship: part_of MA:0002696 ! small intestine wall + +[Term] +id: MA:0001563 +name: small intestine villus +xref: EMAPS:3578428 +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0001564 +name: midgut +xref: EMAPS:1625528 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0001565 +name: esophagus epithelium +synonym: "oesophagus epithelium" RELATED [] +xref: EMAPS:1683528 +is_a: MA:0001520 ! gastrointestinal system epithelium +relationship: part_of MA:0002680 ! esophagus mucosa + +[Term] +id: MA:0001566 +name: esophagus basal epithelium +synonym: "basal oesophageal epithelium" RELATED [] +xref: EMAPS:3532128 +is_a: MA:0001565 ! esophagus epithelium + +[Term] +id: MA:0001567 +name: esophagus squamous epithelium +synonym: "squamous oesophageal epithelium" RELATED [] +xref: EMAPS:3532428 +is_a: MA:0001565 ! esophagus epithelium + +[Term] +id: MA:0001568 +name: esophagus lamina propria +synonym: "oesophagus lamina propria" RELATED [] +xref: EMAPS:2698728 +is_a: MA:0001899 ! gastrointestinal system lamina propria +relationship: part_of MA:0002680 ! esophagus mucosa + +[Term] +id: MA:0001569 +name: esophagus mesentery +synonym: "oesophagus mesentery" RELATED [] +xref: EMAPS:1683628 +is_a: MA:0001900 ! gastrointestinal system mesentery +relationship: part_of MA:0000352 ! esophagus + +[Term] +id: MA:0001570 +name: dorsal meso-esophagus +synonym: "dorsal meso-oesophagus" RELATED [] +xref: EMAPS:1670428 +is_a: MA:0001569 ! esophagus mesentery + +[Term] +id: MA:0001571 +name: esophagus serosa +synonym: "oesophagus serosa" RELATED [] +xref: EMAPS:3532228 +is_a: MA:0001522 ! gastrointestinal system serosa +relationship: part_of MA:0002691 ! esophagus wall + +[Term] +id: MA:0001572 +name: esophagus skeletal muscle +synonym: "oesophagus skeletal muscle" RELATED [] +relationship: part_of MA:0002682 ! esophagus muscle + +[Term] +id: MA:0001573 +name: esophagus smooth muscle +synonym: "oesophagus smooth muscle" RELATED [] +xref: EMAPS:3532328 +is_a: MA:0001523 ! gastrointestinal system smooth muscle +relationship: part_of MA:0002682 ! esophagus muscle + +[Term] +id: MA:0001574 +name: esophagus smooth muscle circular layer +synonym: "esophagus smooth muscle circular layer" RELATED [] +relationship: part_of MA:0001573 ! esophagus smooth muscle + +[Term] +id: MA:0001575 +name: esophagus smooth muscle longitudinal layer +synonym: "esophagus smooth muscle longitudinal layer" RELATED [] +relationship: part_of MA:0001573 ! esophagus smooth muscle + +[Term] +id: MA:0001576 +name: gingival epithelium +relationship: part_of MA:0000342 ! gingiva + +[Term] +id: MA:0001577 +name: lip philtrum +relationship: part_of MA:0000343 ! lip + +[Term] +id: MA:0001578 +name: lip skeletal muscle +relationship: part_of MA:0000343 ! lip + +[Term] +id: MA:0001579 +name: lip skin +relationship: part_of MA:0000343 ! lip + +[Term] +id: MA:0001580 +name: Meckel's cartilage +xref: EMAPS:1762528 +is_a: MA:0000345 ! oral region cartilage/bone + +[Term] +id: MA:0001581 +name: palatal shelf +xref: EMAPS:1736228 +is_a: MA:0000345 ! oral region cartilage/bone + +[Term] +id: MA:0001582 +name: endocrine pancreas +xref: EMAPS:3530528 +is_a: MA:0002563 ! endocrine gland +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0001583 +name: primary palate +xref: EMAPS:1764228 +is_a: MA:0000345 ! oral region cartilage/bone + +[Term] +id: MA:0001584 +name: palatine gland +xref: EMAPS:3564328 +is_a: MA:0002479 ! minor salivary gland + +[Term] +id: MA:0001585 +name: parotid gland +xref: EMAPS:1853728 +is_a: MA:0002478 ! major salivary gland + +[Term] +id: MA:0001586 +name: salivary duct +xref: EMAPS:3575028 +relationship: part_of MA:0000346 ! salivary gland + +[Term] +id: MA:0001587 +name: salivary gland epithelium +xref: EMAPS:3281628 +relationship: part_of MA:0000346 ! salivary gland + +[Term] +id: MA:0001588 +name: sublingual gland +xref: EMAPS:1880928 +is_a: MA:0002478 ! major salivary gland + +[Term] +id: MA:0001589 +name: submandibular gland +synonym: "submaxillary gland" RELATED [] +xref: EMAPS:1881228 +is_a: MA:0002478 ! major salivary gland + +[Term] +id: MA:0001590 +name: intermolar eminence +xref: EMAPS:1827328 +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0001591 +name: taste bud +xref: EMAPS:3585028 +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0001592 +name: tongue epithelium +xref: EMAPS:1788128 +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0001593 +name: tongue papilla +xref: EMAPS:3277728 +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0001594 +name: circumvallate papilla +xref: EMAPS:1827128 +is_a: MA:0001593 ! tongue papilla + +[Term] +id: MA:0001595 +name: fungiform papilla +xref: EMAPS:1827228 +is_a: MA:0001593 ! tongue papilla + +[Term] +id: MA:0001596 +name: tongue skeletal muscle +xref: EMAPS:1788328 +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0001597 +name: dental lamina +xref: EMAPS:3290228 +relationship: part_of MA:0003151 ! tooth epithelium + +[Term] +id: MA:0001598 +name: dental papilla +xref: EMAPS:3289228 +relationship: part_of MA:0003152 ! tooth mesenchyme + +[Term] +id: MA:0001599 +name: dental pulp +xref: EMAPS:3527428 +relationship: part_of MA:0000348 ! tooth + +[Term] +id: MA:0001600 +name: lower jaw incisor +xref: EMAPS:1791828 +is_a: MA:0000349 ! incisor +is_a: MA:0001907 ! lower jaw tooth + +[Term] +id: MA:0001601 +name: upper jaw incisor +xref: EMAPS:1793928 +is_a: MA:0000349 ! incisor +is_a: MA:0001909 ! upper jaw tooth + +[Term] +id: MA:0001602 +name: lower jaw molar +xref: EMAPS:1792128 +is_a: MA:0000350 ! molar +is_a: MA:0001907 ! lower jaw tooth + +[Term] +id: MA:0001603 +name: upper jaw molar +xref: EMAPS:1794228 +is_a: MA:0000350 ! molar +is_a: MA:0001909 ! upper jaw tooth + +[Term] +id: MA:0001604 +name: tooth enamel organ +xref: EMAPS:3288828 +relationship: part_of MA:0003151 ! tooth epithelium + +[Term] +id: MA:0001605 +name: oropharynx epithelium +is_a: MA:0001520 ! gastrointestinal system epithelium +is_a: MA:0002725 ! pharynx epithelium +relationship: part_of MA:0000351 ! oropharynx + +[Term] +id: MA:0001606 +name: forestomach +xref: EMAPS:3535128 +relationship: part_of MA:0000353 ! stomach + +[Term] +id: MA:0001608 +name: stomach blind ventricular sac +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001609 +name: stomach cardiac region +xref: EMAPS:3581128 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001610 +name: stomach epithelium +synonym: "gastric epithelium" RELATED [] +xref: EMAPS:1702328 +is_a: MA:0001520 ! gastrointestinal system epithelium +relationship: part_of MA:0002683 ! stomach mucosa + +[Term] +id: MA:0001611 +name: stomach squamous epithelium +xref: EMAPS:3582428 +is_a: MA:0001610 ! stomach epithelium + +[Term] +id: MA:0001612 +name: stomach fundus +synonym: "gastric fundus" RELATED [] +xref: EMAPS:1788628 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001613 +name: stomach glandular region +xref: EMAPS:1762328 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001614 +name: stomach glandular region mucosa +xref: EMAPS:2716728 +is_a: MA:0002683 ! stomach mucosa +relationship: part_of MA:0001613 ! stomach glandular region + +[Term] +id: MA:0001615 +name: stomach greater curvature +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001616 +name: stomach lesser curvature +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001617 +name: stomach mesentery +synonym: "mesogastrium" RELATED [] +xref: EMAPS:1702428 +is_a: MA:0001900 ! gastrointestinal system mesentery +relationship: part_of MA:0000353 ! stomach + +[Term] +id: MA:0001618 +name: dorsal mesogastrium +xref: EMAPS:1702528 +is_a: MA:0001617 ! stomach mesentery + +[Term] +id: MA:0001619 +name: gastro-splenic ligament +xref: EMAPS:1828528 +is_a: MA:0003004 ! nonskeletal ligament +relationship: part_of MA:0001618 ! dorsal mesogastrium + +[Term] +id: MA:0001620 +name: lieno-renal ligament +xref: EMAPS:1828628 +is_a: MA:0003004 ! nonskeletal ligament +relationship: part_of MA:0001618 ! dorsal mesogastrium + +[Term] +id: MA:0001621 +name: ventral mesogastrium +xref: EMAPS:1702628 +is_a: MA:0001617 ! stomach mesentery + +[Term] +id: MA:0001622 +name: falciform ligament +xref: EMAPS:1828828 +is_a: MA:0003004 ! nonskeletal ligament +relationship: part_of MA:0001621 ! ventral mesogastrium + +[Term] +id: MA:0001623 +name: lesser omentum +xref: EMAPS:1789028 +relationship: part_of MA:0001621 ! ventral mesogastrium + +[Term] +id: MA:0001624 +name: stomach pyloric antrum +alt_id: MA:0001607 +synonym: "gastric antrum" RELATED [] +synonym: "stomach antrum" RELATED [] +xref: EMAPS:1789128 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001625 +name: stomach proventricular region +xref: EMAPS:1762728 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0001626 +name: stomach serosa +synonym: "gastric serosa" RELATED [] +xref: EMAPS:3582228 +is_a: MA:0001522 ! gastrointestinal system serosa +relationship: part_of MA:0002692 ! stomach wall + +[Term] +id: MA:0001627 +name: stomach smooth muscle +synonym: "gastric smooth muscle" RELATED [] +xref: EMAPS:3582328 +is_a: MA:0001523 ! gastrointestinal system smooth muscle +relationship: part_of MA:0002692 ! stomach wall + +[Term] +id: MA:0001628 +name: stomach smooth muscle circular layer +relationship: part_of MA:0001627 ! stomach smooth muscle + +[Term] +id: MA:0001629 +name: bile duct epithelium +relationship: part_of MA:0000354 ! bile duct + +[Term] +id: MA:0001630 +name: bile duct intrahepatic part +relationship: part_of MA:0000354 ! bile duct +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0001631 +name: common bile duct +xref: EMAPS:1720128 +relationship: part_of MA:0002659 ! bile duct extrahepatic part + +[Term] +id: MA:0001632 +name: gall bladder epithelium +synonym: "biliary epithelium" RELATED [] +xref: EMAPS:3537028 +relationship: part_of MA:0000356 ! gall bladder + +[Term] +id: MA:0001633 +name: gall bladder lamina propria +synonym: "biliary lamina propria" RELATED [] +xref: EMAPS:3537128 +relationship: part_of MA:0000356 ! gall bladder + +[Term] +id: MA:0001634 +name: gall bladder serosa +synonym: "biliary serosa" RELATED [] +xref: EMAPS:3537228 +relationship: part_of MA:0000356 ! gall bladder + +[Term] +id: MA:0001635 +name: gall bladder smooth muscle +synonym: "biliary smooth muscle" RELATED [] +xref: EMAPS:3537328 +relationship: part_of MA:0000356 ! gall bladder + +[Term] +id: MA:0001636 +name: hepatic duct extrahepatic part +xref: EMAPS:1684428 +relationship: part_of MA:0000357 ! hepatic duct +relationship: part_of MA:0002659 ! bile duct extrahepatic part + +[Term] +id: MA:0001637 +name: hepatic duct intrahepatic part +xref: EMAPS:1684528 +relationship: part_of MA:0000357 ! hepatic duct +relationship: part_of MA:0001630 ! bile duct intrahepatic part + +[Term] +id: MA:0001638 +name: left hepatic duct +xref: EMAPS:3279528 +relationship: part_of MA:0000357 ! hepatic duct + +[Term] +id: MA:0001639 +name: right hepatic duct +xref: EMAPS:3279728 +relationship: part_of MA:0000357 ! hepatic duct + +[Term] +id: MA:0001640 +name: hepatic duct smooth muscle +relationship: part_of MA:0000357 ! hepatic duct + +[Term] +id: MA:0001641 +name: liver left lateral lobe +is_a: MA:0000361 ! liver left lobe + +[Term] +id: MA:0001642 +name: liver left medial lobe +is_a: MA:0000361 ! liver left lobe + +[Term] +id: MA:0001643 +name: liver papillary process +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0001644 +name: major calyx +xref: EMAPS:1867728 +is_a: MA:0000369 ! kidney calyx + +[Term] +id: MA:0001645 +name: minor calyx +xref: EMAPS:1867828 +is_a: MA:0000369 ! kidney calyx + +[Term] +id: MA:0001646 +name: papillary duct +synonym: "duct of bellini" RELATED [] +xref: EMAPS:3565528 +is_a: MA:0000371 ! kidney collecting duct + +[Term] +id: MA:0001647 +name: area cribosa +relationship: part_of MA:0001646 ! papillary duct + +[Term] +id: MA:0001648 +name: juxtamedullary cortex +is_a: MA:0000372 ! kidney cortex + +[Term] +id: MA:0001649 +name: kidney outer cortex +synonym: "outer renal cortex" RELATED [] +is_a: MA:0000372 ! kidney cortex + +[Term] +id: MA:0001650 +name: cortical arch +relationship: part_of MA:0001649 ! kidney outer cortex + +[Term] +id: MA:0001651 +name: kidney column +synonym: "renal column" RELATED [] +relationship: part_of MA:0001649 ! kidney outer cortex + +[Term] +id: MA:0001652 +name: kidney inner medulla +xref: EMAPS:2834928 +relationship: part_of MA:0000373 ! kidney medulla + +[Term] +id: MA:0001653 +name: kidney outer medulla +xref: EMAPS:2831028 +relationship: part_of MA:0000373 ! kidney medulla + +[Term] +id: MA:0001654 +name: kidney pyramid +synonym: "renal pyramid" RELATED [] +relationship: part_of MA:0000373 ! kidney medulla + +[Term] +id: MA:0001655 +name: left kidney +is_a: MA:0000368 ! kidney + +[Term] +id: MA:0001657 +name: glomerulus +synonym: "glomerular tuft" RELATED [] +xref: EMAPS:2832928 +relationship: part_of MA:0000376 ! renal corpuscle + +[Term] +id: MA:0001658 +name: glomerular capillary endothelium +relationship: part_of MA:0002587 ! glomerular capillary + +[Term] +id: MA:0001659 +name: glomerular capillary basement membrane +xref: EMAPS:2825128 +relationship: part_of MA:0002587 ! glomerular capillary + +[Term] +id: MA:0001660 +name: glomerular capsule +synonym: "bowman's capsule" RELATED [] +xref: EMAPS:2825728 +relationship: part_of MA:0000376 ! renal corpuscle + +[Term] +id: MA:0001661 +name: glomerular juxtacapillary capsular wall +relationship: part_of MA:0001660 ! glomerular capsule + +[Term] +id: MA:0001662 +name: glomerular outer capsular wall +relationship: part_of MA:0001660 ! glomerular capsule + +[Term] +id: MA:0001663 +name: juxtamedullary renal corpuscle +is_a: MA:0000376 ! renal corpuscle +relationship: part_of MA:0001648 ! juxtamedullary cortex + +[Term] +id: MA:0001664 +name: urinary space +synonym: "bowman's space" RELATED [] +xref: EMAPS:2826328 +relationship: part_of MA:0000376 ! renal corpuscle + +[Term] +id: MA:0001665 +name: kidney convoluted tubule +xref: EMAPS:3572528 +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0001666 +name: distal convoluted tubule +synonym: "second convoluted tubule" RELATED [] +xref: EMAPS:2839328 +is_a: MA:0001665 ! kidney convoluted tubule +is_a: MA:0002609 ! kidney cortex tubule +is_a: MA:0002633 ! kidney distal tubule + +[Term] +id: MA:0001667 +name: distal convoluted tubule convoluted part +relationship: part_of MA:0001666 ! distal convoluted tubule + +[Term] +id: MA:0001668 +name: distal convoluted tubule macula densa +relationship: part_of MA:0001666 ! distal convoluted tubule +relationship: part_of MA:0002603 ! macula densa + +[Term] +id: MA:0001669 +name: proximal convoluted tubule +synonym: "first convoluted tubule" RELATED [] +xref: EMAPS:2828728 +is_a: MA:0001665 ! kidney convoluted tubule +is_a: MA:0002609 ! kidney cortex tubule +is_a: MA:0002611 ! kidney proximal tubule + +[Term] +id: MA:0001670 +name: proximal convoluted tubule neck +relationship: part_of MA:0001669 ! proximal convoluted tubule + +[Term] +id: MA:0001671 +name: proximal convoluted tubule convoluted part +relationship: part_of MA:0001669 ! proximal convoluted tubule + +[Term] +id: MA:0001672 +name: proximal convoluted tubule straight part +relationship: part_of MA:0001669 ! proximal convoluted tubule + +[Term] +id: MA:0001673 +name: distal convoluted tubule straight part +relationship: part_of MA:0001666 ! distal convoluted tubule + +[Term] +id: MA:0001674 +name: junctional tubule +synonym: "connecting tubule" RELATED [] +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0001675 +name: loop of henle +xref: EMAPS:1928028 +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0001676 +name: loop of henle ascending limb +xref: EMAPS:3551028 +relationship: part_of MA:0001675 ! loop of henle + +[Term] +id: MA:0001677 +name: loop of henle ascending limb thick segment +synonym: "distal straight tubule" RELATED [] +xref: EMAPS:2839628 +xref: EMAPS:3551228 +is_a: MA:0002633 ! kidney distal tubule +is_a: MA:0002634 ! kidney straight tubule +relationship: part_of MA:0001676 ! loop of henle ascending limb + +[Term] +id: MA:0001678 +name: loop of henle ascending limb thin segment +xref: EMAPS:2836128 +relationship: part_of MA:0001676 ! loop of henle ascending limb +relationship: part_of MA:0002623 ! kidney inner medulla loop of henle + +[Term] +id: MA:0001679 +name: loop of henle descending limb +xref: EMAPS:3551128 +relationship: part_of MA:0001675 ! loop of henle + +[Term] +id: MA:0001680 +name: kidney tubule basement membrane +relationship: part_of MA:0000377 ! kidney tubule + +[Term] +id: MA:0001681 +name: kidney tubule epithelium +is_a: MA:0002846 ! kidney epithelium +relationship: part_of MA:0000377 ! kidney tubule + +[Term] +id: MA:0001682 +name: kidney blood vessel +synonym: "renal blood vessel" RELATED [] +xref: EMAPS:2845728 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0001683 +name: right kidney +is_a: MA:0000368 ! kidney + +[Term] +id: MA:0001684 +name: left ureter +is_a: MA:0000378 ! ureter + +[Term] +id: MA:0001685 +name: right ureter +is_a: MA:0000378 ! ureter + +[Term] +id: MA:0001686 +name: urethra epithelium +synonym: "urethral epithelium" RELATED [] +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0001687 +name: urethra urothelium +xref: EMAPS:3589628 +is_a: MA:0001686 ! urethra epithelium + +[Term] +id: MA:0001688 +name: urethra gland +synonym: "urethral gland" RELATED [] +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0001689 +name: urethra lamina propria +synonym: "urethral lamina propria" RELATED [] +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0001690 +name: urethra skeletal muscle +synonym: "urethral skeletal muscle" RELATED [] +relationship: part_of MA:0002649 ! urethra muscle + +[Term] +id: MA:0001691 +name: urethra smooth muscle +synonym: "urethral smooth muscle" RELATED [] +relationship: part_of MA:0002649 ! urethra muscle + +[Term] +id: MA:0001692 +name: urinary bladder mucosa +synonym: "urinary bladder mucosa" RELATED [] +xref: EMAPS:3589728 +relationship: part_of MA:0002493 ! urinary bladder wall + +[Term] +id: MA:0001693 +name: urinary bladder urothelium +synonym: "transitional epithelium" RELATED [] +xref: EMAPS:2860128 +relationship: part_of MA:0001692 ! urinary bladder mucosa + +[Term] +id: MA:0001694 +name: urinary bladder fundus region +xref: EMAPS:3517328 +relationship: part_of MA:0000380 ! urinary bladder + +[Term] +id: MA:0001695 +name: urinary bladder lamina propria +xref: EMAPS:3008828 +relationship: part_of MA:0001692 ! urinary bladder mucosa + +[Term] +id: MA:0001696 +name: urinary bladder serosa +xref: EMAPS:2866128 +relationship: part_of MA:0002493 ! urinary bladder wall + +[Term] +id: MA:0001697 +name: urinary bladder muscle +relationship: part_of MA:0002493 ! urinary bladder wall + +[Term] +id: MA:0001698 +name: urinary bladder detrusor muscle +xref: EMAPS:2863728 +is_a: MA:0001697 ! urinary bladder muscle + +[Term] +id: MA:0001699 +name: urinary bladder neck muscle +xref: EMAPS:3012328 +is_a: MA:0001697 ! urinary bladder muscle + +[Term] +id: MA:0001700 +name: urinary bladder trigone muscle +xref: EMAPS:2864928 +is_a: MA:0001697 ! urinary bladder muscle + +[Term] +id: MA:0001701 +name: urachus +xref: EMAPS:1832328 +relationship: part_of MA:0000380 ! urinary bladder + +[Term] +id: MA:0001702 +name: clitoral gland +alt_id: MA:0001703 +synonym: "female preputial gland" EXACT [] +synonym: "preputial gland of female" RELATED [] +is_a: MA:0000383 ! female reproductive gland +is_a: MA:0003044 ! clitoral/preputial gland + +[Term] +id: MA:0001704 +name: left ovary +is_a: MA:0000384 ! ovary + +[Term] +id: MA:0001705 +name: right ovary +is_a: MA:0000384 ! ovary + +[Term] +id: MA:0001706 +name: ovary capsule +xref: EMAPS:3562628 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0001707 +name: ovary follicle +xref: EMAPS:3562728 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0001708 +name: ovary growing follicle +xref: EMAPS:3562828 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0001709 +name: ovary mature follicle +xref: EMAPS:3562928 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0001710 +name: ovary primordial follicle +xref: EMAPS:3075528 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0001711 +name: ovary germinal epithelium +xref: EMAPS:1796328 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0001712 +name: ovary theca +xref: EMAPS:3563628 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0001713 +name: ovary theca externa +is_a: MA:0001712 ! ovary theca + +[Term] +id: MA:0001714 +name: ovary theca interna +is_a: MA:0001712 ! ovary theca + +[Term] +id: MA:0001715 +name: zona pellucida +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0001716 +name: left oviduct +is_a: MA:0000385 ! oviduct + +[Term] +id: MA:0001717 +name: right oviduct +is_a: MA:0000385 ! oviduct + +[Term] +id: MA:0001718 +name: oviduct epithelium +xref: EMAPS:2904328 +relationship: part_of MA:0000385 ! oviduct + +[Term] +id: MA:0001719 +name: ciliated columnar oviduct epithelium +is_a: MA:0001718 ! oviduct epithelium + +[Term] +id: MA:0001720 +name: cuboidal oviduct epithelium +is_a: MA:0001718 ! oviduct epithelium + +[Term] +id: MA:0001721 +name: oviduct smooth muscle +xref: EMAPS:2904628 +relationship: part_of MA:0000385 ! oviduct + +[Term] +id: MA:0001722 +name: decidua +synonym: "decidua basalis" RELATED [] +xref: EMAPS:3526928 +relationship: part_of MA:0000386 ! placenta + +[Term] +id: MA:0001723 +name: placenta metrial gland +relationship: part_of MA:0000386 ! placenta + +[Term] +id: MA:0001724 +name: cervix epithelium +xref: EMAPS:2992928 +relationship: part_of MA:0000392 ! uterine cervix + +[Term] +id: MA:0001725 +name: cervix squamous epithelium +is_a: MA:0001724 ! cervix epithelium + +[Term] +id: MA:0001726 +name: uterine gland +xref: EMAPS:2991928 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0001727 +name: left uterine horn +is_a: MA:0000393 ! uterine horn + +[Term] +id: MA:0001728 +name: right uterine horn +is_a: MA:0000393 ! uterine horn + +[Term] +id: MA:0001729 +name: uterus serosa +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0001730 +name: vagina epithelium +xref: EMAPS:3099128 +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0001731 +name: vagina squamous epithelium +is_a: MA:0001730 ! vagina epithelium + +[Term] +id: MA:0001732 +name: vagina sebaceous gland +is_a: MA:0002565 ! sebaceous gland +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0001733 +name: vagina smooth muscle +xref: EMAPS:3099728 +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0001734 +name: efferent duct epithelium +xref: EMAPS:2974728 +relationship: part_of MA:0000398 ! efferent duct + +[Term] +id: MA:0001735 +name: epididymal duct +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0001736 +name: epididymis smooth muscle +xref: EMAPS:3044728 +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0001737 +name: prostate gland epithelium +xref: EMAPS:3229028 +relationship: part_of MA:0000404 ! prostate gland + +[Term] +id: MA:0001738 +name: prostate gland lobe +xref: EMAPS:3571228 +relationship: part_of MA:0000404 ! prostate gland + +[Term] +id: MA:0001739 +name: prostate gland dorsolateral lobe +xref: EMAPS:3571028 +is_a: MA:0001738 ! prostate gland lobe + +[Term] +id: MA:0001740 +name: prostate gland ventral lobe +xref: EMAPS:2983628 +is_a: MA:0001738 ! prostate gland lobe + +[Term] +id: MA:0001741 +name: prostate gland smooth muscle +xref: EMAPS:3571328 +relationship: part_of MA:0000404 ! prostate gland + +[Term] +id: MA:0001742 +name: penis epithelium +xref: EMAPS:3567428 +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0001743 +name: penis erectile tissue +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0001744 +name: penis foreskin +relationship: part_of MA:0002727 ! penis skin + +[Term] +id: MA:0001745 +name: seminal vesicle epithelium +xref: EMAPS:2977128 +relationship: part_of MA:0000410 ! seminal vesicle + +[Term] +id: MA:0001746 +name: left testis +is_a: MA:0000411 ! testis + +[Term] +id: MA:0001747 +name: right testis +is_a: MA:0000411 ! testis + +[Term] +id: MA:0001748 +name: seminiferous tubule epithelium +xref: EMAPS:3576128 +relationship: part_of MA:0000412 ! seminiferous tubule + +[Term] +id: MA:0001749 +name: vas deferens epithelium +relationship: part_of MA:0000413 ! vas deferens + +[Term] +id: MA:0001750 +name: vas deferens smooth muscle +xref: EMAPS:2927028 +relationship: part_of MA:0000413 ! vas deferens + +[Term] +id: MA:0001751 +name: reproductive gland +relationship: part_of MA:0000326 ! reproductive system + +[Term] +id: MA:0001752 +name: reproductive organ +relationship: part_of MA:0000326 ! reproductive system + +[Term] +id: MA:0001753 +name: prepuce epithelium +relationship: part_of MA:0000407 ! prepuce + +[Term] +id: MA:0001754 +name: larynx connective tissue +xref: EMAPS:3547128 +is_a: MA:0001814 ! respiratory system connective tissue +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0001755 +name: larynx ligament +synonym: "laryngeal ligament" RELATED [] +synonym: "ligament of larynx" RELATED [] +is_a: MA:0001754 ! larynx connective tissue +is_a: MA:0003004 ! nonskeletal ligament + +[Term] +id: MA:0001756 +name: laryngeal extrinsic ligament +is_a: MA:0001755 ! larynx ligament + +[Term] +id: MA:0001757 +name: laryngeal intrinsic ligament +is_a: MA:0001755 ! larynx ligament + +[Term] +id: MA:0001758 +name: larynx cartilage +xref: EMAPS:1869728 +is_a: MA:0000104 ! cartilage tissue +is_a: MA:0000586 ! neck cartilage +is_a: MA:0001754 ! larynx connective tissue +is_a: MA:0001818 ! respiratory system cartilage + +[Term] +id: MA:0001759 +name: arytenoid cartilage +xref: EMAPS:1869528 +is_a: MA:0001758 ! larynx cartilage + +[Term] +id: MA:0001760 +name: apex of arytenoid +is_a: MA:0000485 ! yellow elastic cartilage +relationship: part_of MA:0001759 ! arytenoid cartilage + +[Term] +id: MA:0001761 +name: base of arytenoid +is_a: MA:0000109 ! hyaline cartilage +relationship: part_of MA:0001759 ! arytenoid cartilage + +[Term] +id: MA:0001762 +name: cricoid cartilage +xref: EMAPS:1869628 +is_a: MA:0001758 ! larynx cartilage + +[Term] +id: MA:0001763 +name: epiglottic cartilage +is_a: MA:0000485 ! yellow elastic cartilage +is_a: MA:0001758 ! larynx cartilage + +[Term] +id: MA:0001764 +name: thyroid cartilage +xref: EMAPS:1869828 +is_a: MA:0001758 ! larynx cartilage + +[Term] +id: MA:0001765 +name: larynx epithelium +xref: EMAPS:3547228 +is_a: MA:0001823 ! respiratory system epithelium +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0001766 +name: larynx mucosa +xref: EMAPS:1833428 +is_a: MA:0001827 ! respiratory system mucosa +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0001767 +name: larynx mucous gland +relationship: part_of MA:0001766 ! larynx mucosa + +[Term] +id: MA:0001768 +name: larynx muscle +xref: EMAPS:3547328 +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0001769 +name: laryngeal extrinsic muscle +is_a: MA:0001768 ! larynx muscle + +[Term] +id: MA:0001770 +name: laryngeal intrinsic muscle +is_a: MA:0001768 ! larynx muscle + +[Term] +id: MA:0001771 +name: alveolus epithelium +xref: EMAPS:3512128 +is_a: MA:0001783 ! lung epithelium +relationship: part_of MA:0002568 ! alveolar wall + +[Term] +id: MA:0001772 +name: bronchiole epithelium +xref: EMAPS:3269328 +is_a: MA:0001783 ! lung epithelium +relationship: part_of MA:0000422 ! bronchiole + +[Term] +id: MA:0001773 +name: respiratory bronchiole epithelium +xref: EMAPS:3573028 +relationship: part_of MA:0000423 ! respiratory bronchiole + +[Term] +id: MA:0001774 +name: terminal bronchiole epithelium +relationship: part_of MA:0000424 ! terminal bronchiole + +[Term] +id: MA:0001775 +name: left lung alveolar system +xref: EMAPS:1900128 +relationship: part_of MA:0000425 ! left lung + +[Term] +id: MA:0001776 +name: left lung alveolar duct +xref: EMAPS:1918328 +relationship: part_of MA:0001775 ! left lung alveolar system + +[Term] +id: MA:0001777 +name: left lung alveolus +xref: EMAPS:1918228 +relationship: part_of MA:0001775 ! left lung alveolar system + +[Term] +id: MA:0001778 +name: left lung bronchiole +xref: EMAPS:1900028 +relationship: part_of MA:0000425 ! left lung + +[Term] +id: MA:0001779 +name: left lung respiratory bronchiole +is_a: MA:0001778 ! left lung bronchiole + +[Term] +id: MA:0001780 +name: left lung terminal bronchiole +is_a: MA:0001778 ! left lung bronchiole + +[Term] +id: MA:0001781 +name: left lung hilus +synonym: "left lung hilum" RELATED [] +xref: EMAPS:1798028 +is_a: MA:0003099 ! lung hilus +relationship: part_of MA:0000425 ! left lung + +[Term] +id: MA:0001782 +name: lung connective tissue +synonym: "lung interstitial tissue" RELATED [] +xref: EMAPS:3552128 +is_a: MA:0001814 ! respiratory system connective tissue +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0001783 +name: lung epithelium +xref: EMAPS:3286028 +is_a: MA:0001823 ! respiratory system epithelium +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0001784 +name: right lung alveolar system +xref: EMAPS:3571728 +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0001785 +name: right lung alveolar duct +xref: EMAPS:3581928 +relationship: part_of MA:0001784 ! right lung alveolar system + +[Term] +id: MA:0001786 +name: right lung alveolus +xref: EMAPS:3599728 +relationship: part_of MA:0001784 ! right lung alveolar system + +[Term] +id: MA:0001787 +name: right lung bronchiole +xref: EMAPS:3542528 +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0001788 +name: right lung respiratory bronchiole +is_a: MA:0001787 ! right lung bronchiole + +[Term] +id: MA:0001789 +name: right lung terminal bronchiole +is_a: MA:0001787 ! right lung bronchiole + +[Term] +id: MA:0001790 +name: right lung hilus +synonym: "right lung hilum" RELATED [] +xref: EMAPS:1799628 +is_a: MA:0003099 ! lung hilus +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0001791 +name: right lung lobe +xref: EMAPS:3515528 +is_a: MA:0003098 ! lung lobe +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0001792 +name: ethmoid sinus +is_a: MA:0000431 ! paranasal sinus + +[Term] +id: MA:0001793 +name: frontal sinus +is_a: MA:0000431 ! paranasal sinus + +[Term] +id: MA:0001794 +name: maxillary sinus +is_a: MA:0000431 ! paranasal sinus + +[Term] +id: MA:0001795 +name: sphenoid sinus +is_a: MA:0000431 ! paranasal sinus + +[Term] +id: MA:0001796 +name: hypopharynx +relationship: part_of MA:0000432 ! pharynx + +[Term] +id: MA:0001797 +name: pharynx muscle +xref: EMAPS:1896328 +relationship: part_of MA:0000432 ! pharynx + +[Term] +id: MA:0001798 +name: pretracheal muscle +xref: EMAPS:1926928 +is_a: MA:0001797 ! pharynx muscle + +[Term] +id: MA:0001799 +name: respiratory system blood vessel +xref: EMAPS:3573128 +xref: EMAPS:3599528 +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001800 +name: respiratory system arterial blood vessel +is_a: MA:0001799 ! respiratory system blood vessel + +[Term] +id: MA:0001801 +name: respiratory system arterial endothelium +relationship: part_of MA:0001800 ! respiratory system arterial blood vessel + +[Term] +id: MA:0001802 +name: respiratory system arterial smooth muscle +relationship: part_of MA:0001800 ! respiratory system arterial blood vessel + +[Term] +id: MA:0001803 +name: respiratory system arteriole +is_a: MA:0001800 ! respiratory system arterial blood vessel + +[Term] +id: MA:0001804 +name: respiratory system artery +is_a: MA:0001800 ! respiratory system arterial blood vessel + +[Term] +id: MA:0001805 +name: respiratory system blood vessel endothelium +xref: EMAPS:3573228 +relationship: part_of MA:0001799 ! respiratory system blood vessel + +[Term] +id: MA:0001806 +name: respiratory system blood vessel smooth muscle +relationship: part_of MA:0001799 ! respiratory system blood vessel + +[Term] +id: MA:0001807 +name: respiratory system capillary +is_a: MA:0001799 ! respiratory system blood vessel + +[Term] +id: MA:0001808 +name: respiratory system capillary endothelium +relationship: part_of MA:0001807 ! respiratory system capillary + +[Term] +id: MA:0001809 +name: respiratory system venous blood vessel +is_a: MA:0001799 ! respiratory system blood vessel + +[Term] +id: MA:0001810 +name: respiratory system vein +is_a: MA:0001809 ! respiratory system venous blood vessel + +[Term] +id: MA:0001811 +name: respiratory system venous endothelium +relationship: part_of MA:0001809 ! respiratory system venous blood vessel + +[Term] +id: MA:0001812 +name: respiratory system venous smooth muscle +relationship: part_of MA:0001809 ! respiratory system venous blood vessel + +[Term] +id: MA:0001813 +name: respiratory system venule +is_a: MA:0001809 ! respiratory system venous blood vessel + +[Term] +id: MA:0001814 +name: respiratory system connective tissue +xref: EMAPS:3596828 +xref: EMAPS:3597728 +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001815 +name: respiratory system basement membrane +relationship: part_of MA:0001814 ! respiratory system connective tissue + +[Term] +id: MA:0001816 +name: respiratory system basal lamina +relationship: part_of MA:0001815 ! respiratory system basement membrane + +[Term] +id: MA:0001817 +name: respiratory system reticular lamina +relationship: part_of MA:0001815 ! respiratory system basement membrane + +[Term] +id: MA:0001818 +name: respiratory system cartilage +xref: EMAPS:1869428 +relationship: part_of MA:0001814 ! respiratory system connective tissue + +[Term] +id: MA:0001819 +name: lower respiratory tract cartilage +is_a: MA:0001818 ! respiratory system cartilage +relationship: part_of MA:0002409 ! lower respiratory tract connective tissue + +[Term] +id: MA:0001820 +name: respiratory system elastic tissue +is_a: MA:0002853 ! elastic tissue +relationship: part_of MA:0001822 ! respiratory system submucosa + +[Term] +id: MA:0001821 +name: respiratory system lamina propria +relationship: part_of MA:0001814 ! respiratory system connective tissue + +[Term] +id: MA:0001822 +name: respiratory system submucosa +relationship: part_of MA:0001814 ! respiratory system connective tissue + +[Term] +id: MA:0001823 +name: respiratory system epithelium +synonym: "respiratory system mucosa" RELATED [] +xref: EMAPS:3282628 +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001824 +name: respiratory system lymphatic vessel +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001825 +name: respiratory system lymphatic vessel endothelium +relationship: part_of MA:0001824 ! respiratory system lymphatic vessel + +[Term] +id: MA:0001826 +name: respiratory system lymphatic vessel smooth muscle +relationship: part_of MA:0001824 ! respiratory system lymphatic vessel + +[Term] +id: MA:0001827 +name: respiratory system mucosa +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001828 +name: respiratory system muscle +xref: EMAPS:3573328 +relationship: part_of MA:0000327 ! respiratory system + +[Term] +id: MA:0001829 +name: respiratory system skeletal muscle +is_a: MA:0001828 ! respiratory system muscle + +[Term] +id: MA:0001830 +name: respiratory system smooth muscle +xref: EMAPS:3573428 +is_a: MA:0001828 ! respiratory system muscle + +[Term] +id: MA:0001831 +name: bronchus connective tissue +xref: EMAPS:3269028 +xref: EMAPS:3519328 +relationship: part_of MA:0000436 ! bronchus +relationship: part_of MA:0002409 ! lower respiratory tract connective tissue + +[Term] +id: MA:0001832 +name: bronchus basement membrane +is_a: MA:0001831 ! bronchus connective tissue + +[Term] +id: MA:0001833 +name: bronchus basal lamina +relationship: part_of MA:0001832 ! bronchus basement membrane + +[Term] +id: MA:0001834 +name: bronchus reticular lamina +relationship: part_of MA:0001832 ! bronchus basement membrane + +[Term] +id: MA:0001835 +name: bronchus cartilage +xref: EMAPS:3519228 +is_a: MA:0001819 ! lower respiratory tract cartilage +is_a: MA:0001831 ! bronchus connective tissue + +[Term] +id: MA:0001836 +name: bronchus lamina propria +xref: EMAPS:3519428 +is_a: MA:0001831 ! bronchus connective tissue + +[Term] +id: MA:0001837 +name: bronchus submucosa +is_a: MA:0001831 ! bronchus connective tissue + +[Term] +id: MA:0001838 +name: bronchus elastic tissue +relationship: part_of MA:0001837 ! bronchus submucosa + +[Term] +id: MA:0001839 +name: bronchus epithelium +xref: EMAPS:3269128 +is_a: MA:0001481 ! lower respiratory tract epithelium +relationship: part_of MA:0000436 ! bronchus + +[Term] +id: MA:0001840 +name: bronchus smooth muscle +xref: EMAPS:3519528 +is_a: MA:0002410 ! lower respiratory tract smooth muscle +relationship: part_of MA:0000436 ! bronchus + +[Term] +id: MA:0001841 +name: lobar bronchus connective tissue +xref: EMAPS:3269828 +relationship: part_of MA:0000437 ! lobar bronchus + +[Term] +id: MA:0001842 +name: lobar bronchus epithelium +xref: EMAPS:3269528 +relationship: part_of MA:0000437 ! lobar bronchus + +[Term] +id: MA:0001843 +name: left main bronchus +is_a: MA:0000438 ! main bronchus + +[Term] +id: MA:0001844 +name: main bronchus blood vessel +xref: EMAPS:1685228 +relationship: part_of MA:0000438 ! main bronchus + +[Term] +id: MA:0001845 +name: main bronchus connective tissue +xref: EMAPS:1685028 +relationship: part_of MA:0000438 ! main bronchus + +[Term] +id: MA:0001846 +name: main bronchus cartilage +xref: EMAPS:1909228 +is_a: MA:0001835 ! bronchus cartilage +is_a: MA:0001845 ! main bronchus connective tissue + +[Term] +id: MA:0001847 +name: main bronchus epithelium +xref: EMAPS:1685128 +relationship: part_of MA:0000438 ! main bronchus + +[Term] +id: MA:0001848 +name: main bronchus smooth muscle +relationship: part_of MA:0000438 ! main bronchus + +[Term] +id: MA:0001849 +name: right main bronchus +is_a: MA:0000438 ! main bronchus + +[Term] +id: MA:0001850 +name: segmental bronchus epithelium +relationship: part_of MA:0000439 ! segmental bronchus + +[Term] +id: MA:0001851 +name: terminal bronchus epithelium +relationship: part_of MA:0000440 ! terminal bronchus + +[Term] +id: MA:0001852 +name: trachea blood vessel +xref: EMAPS:3587428 +relationship: part_of MA:0000441 ! trachea + +[Term] +id: MA:0001853 +name: trachea connective tissue +xref: EMAPS:3587628 +is_a: MA:0001814 ! respiratory system connective tissue +relationship: part_of MA:0000441 ! trachea +relationship: part_of MA:0002409 ! lower respiratory tract connective tissue + +[Term] +id: MA:0001854 +name: trachea basement membrane +is_a: MA:0001859 ! trachea non-cartilage connective tissue + +[Term] +id: MA:0001855 +name: trachea basal lamina +relationship: part_of MA:0001854 ! trachea basement membrane + +[Term] +id: MA:0001856 +name: trachea reticular lamina +relationship: part_of MA:0001854 ! trachea basement membrane + +[Term] +id: MA:0001857 +name: trachea cartilage +xref: EMAPS:3587528 +is_a: MA:0000104 ! cartilage tissue +is_a: MA:0000586 ! neck cartilage +is_a: MA:0001819 ! lower respiratory tract cartilage +is_a: MA:0001853 ! trachea connective tissue + +[Term] +id: MA:0001858 +name: trachea lamina propria +xref: EMAPS:3587728 +is_a: MA:0001859 ! trachea non-cartilage connective tissue + +[Term] +id: MA:0001859 +name: trachea non-cartilage connective tissue +xref: EMAPS:3587828 +is_a: MA:0001853 ! trachea connective tissue + +[Term] +id: MA:0001860 +name: trachea submucosa +xref: EMAPS:3587928 +is_a: MA:0001859 ! trachea non-cartilage connective tissue + +[Term] +id: MA:0001861 +name: trachea elastic tissue +is_a: MA:0001820 ! respiratory system elastic tissue +relationship: part_of MA:0001860 ! trachea submucosa + +[Term] +id: MA:0001862 +name: trachea epithelium +xref: EMAPS:1685528 +is_a: MA:0001481 ! lower respiratory tract epithelium +relationship: part_of MA:0000441 ! trachea + +[Term] +id: MA:0001863 +name: trachea smooth muscle +xref: EMAPS:1919228 +is_a: MA:0001830 ! respiratory system smooth muscle +is_a: MA:0002410 ! lower respiratory tract smooth muscle +relationship: part_of MA:0000441 ! trachea + +[Term] +id: MA:0001864 +name: nasopharynx connective tissue +is_a: MA:0001814 ! respiratory system connective tissue +relationship: part_of MA:0000443 ! nasopharynx + +[Term] +id: MA:0001865 +name: nasopharynx epithelium +is_a: MA:0001912 ! upper respiratory tract epithelium +is_a: MA:0002725 ! pharynx epithelium +relationship: part_of MA:0000443 ! nasopharynx + +[Term] +id: MA:0001866 +name: pampiniform plexus +alt_id: MA:0002188 +is_a: MA:0000069 ! venous plexus + +[Term] +id: MA:0001867 +name: superior sagittal sinus +xref: EMAPS:1863628 +is_a: MA:0000070 ! venous sinus + +[Term] +id: MA:0001868 +name: transverse sinus +xref: EMAPS:1863728 +is_a: MA:0000070 ! venous sinus + +[Term] +id: MA:0001869 +name: left atrium auricular region +synonym: "left atrial appendage" RELATED [] +xref: EMAPS:1731628 +is_a: MA:0002955 ! atrium auricular region +relationship: part_of MA:0000074 ! heart left atrium + +[Term] +id: MA:0001870 +name: right atrium auricular region +synonym: "right atrial appendage" RELATED [] +xref: EMAPS:1732228 +is_a: MA:0002955 ! atrium auricular region +relationship: part_of MA:0000075 ! heart right atrium + +[Term] +id: MA:0001871 +name: right atrium valve +xref: EMAPS:1732728 +relationship: part_of MA:0000075 ! heart right atrium + +[Term] +id: MA:0001872 +name: right atrium venous valve +xref: EMAPS:1732828 +is_a: MA:0001871 ! right atrium valve + +[Term] +id: MA:0001873 +name: foramen ovale +xref: EMAPS:1824428 +relationship: part_of MA:0000084 ! interatrial septum + +[Term] +id: MA:0001874 +name: left ventricle membranous part +is_a: MA:0001878 ! heart ventricle membranous part +relationship: part_of MA:0000092 ! heart left ventricle + +[Term] +id: MA:0001875 +name: left ventricle muscular part +is_a: MA:0001879 ! heart ventricle muscular part +relationship: part_of MA:0000092 ! heart left ventricle + +[Term] +id: MA:0001876 +name: right ventricle membranous part +is_a: MA:0001878 ! heart ventricle membranous part +relationship: part_of MA:0000093 ! heart right ventricle + +[Term] +id: MA:0001877 +name: right ventricle muscular part +is_a: MA:0001879 ! heart ventricle muscular part +relationship: part_of MA:0000093 ! heart right ventricle + +[Term] +id: MA:0001878 +name: heart ventricle membranous part +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0001879 +name: heart ventricle muscular part +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0001880 +name: transverse pericardial sinus +xref: EMAPS:1621428 +relationship: part_of MA:0000482 ! dorsal mesocardium + +[Term] +id: MA:0001881 +name: outflow tract pulmonary component distal part +xref: EMAPS:3562428 +relationship: part_of MA:0000102 ! outflow tract pulmonary component + +[Term] +id: MA:0001882 +name: outflow tract pulmonary component proximal part +xref: EMAPS:1761928 +relationship: part_of MA:0000102 ! outflow tract pulmonary component + +[Term] +id: MA:0001883 +name: nasal cartilage +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0001884 +name: xiphoid cartilage +synonym: "xiphoid process" RELATED [] +is_a: MA:0000104 ! cartilage tissue + +[Term] +id: MA:0001885 +name: corniculate cartilage +is_a: MA:0000485 ! yellow elastic cartilage + +[Term] +id: MA:0001886 +name: external ear cartilage +is_a: MA:0000485 ! yellow elastic cartilage + +[Term] +id: MA:0001887 +name: adrenal gland cortex zone +xref: EMAPS:3511328 +relationship: part_of MA:0000118 ! adrenal gland cortex + +[Term] +id: MA:0001888 +name: adrenal gland X zone +synonym: "juvenile zone" RELATED [] +is_a: MA:0001887 ! adrenal gland cortex zone + +[Term] +id: MA:0001889 +name: adrenal gland brown degeneration zone +is_a: MA:0001887 ! adrenal gland cortex zone + +[Term] +id: MA:0001890 +name: adrenal gland zona fasciculata +xref: EMAPS:3511428 +is_a: MA:0001887 ! adrenal gland cortex zone + +[Term] +id: MA:0001891 +name: adrenal gland zona glomerulosa +xref: EMAPS:3511528 +is_a: MA:0001887 ! adrenal gland cortex zone + +[Term] +id: MA:0001892 +name: adrenal gland zona reticularis +xref: EMAPS:3511628 +is_a: MA:0001887 ! adrenal gland cortex zone + +[Term] +id: MA:0001893 +name: auchene hair +is_a: MA:0001897 ! pelage hair + +[Term] +id: MA:0001894 +name: awl hair +is_a: MA:0001897 ! pelage hair + +[Term] +id: MA:0001895 +name: duvet hair +is_a: MA:0000155 ! coat hair + +[Term] +id: MA:0001896 +name: guard hair +is_a: MA:0001897 ! pelage hair + +[Term] +id: MA:0001897 +name: pelage hair +is_a: MA:0000155 ! coat hair + +[Term] +id: MA:0001898 +name: zigzag hair +is_a: MA:0001897 ! pelage hair + +[Term] +id: MA:0001899 +name: gastrointestinal system lamina propria +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001900 +name: gastrointestinal system mesentery +relationship: part_of MA:0000323 ! alimentary system + +[Term] +id: MA:0001901 +name: back organ +is_a: MA:0000516 ! trunk organ +relationship: part_of MA:0000020 ! back of trunk + +[Term] +id: MA:0001902 +name: thoracic cavity artery +is_a: MA:0000554 ! thoracic cavity blood vessel + +[Term] +id: MA:0001903 +name: thoracic cavity vein +is_a: MA:0000554 ! thoracic cavity blood vessel + +[Term] +id: MA:0001904 +name: diaphragm +xref: EMAPS:1770128 +is_a: MA:0000005 ! body cavity or lining +is_a: MA:0001829 ! respiratory system skeletal muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0001905 +name: jaw +alt_id: MA:0001479 +synonym: "jaw" RELATED [] +xref: EMAPS:3290528 +relationship: part_of MA:0000318 ! viscerocranium +relationship: part_of MA:0001910 ! snout + +[Term] +id: MA:0001906 +name: lower jaw +xref: EMAPS:1790628 +relationship: part_of MA:0001905 ! jaw + +[Term] +id: MA:0001907 +name: lower jaw tooth +xref: EMAPS:1791728 +is_a: MA:0000348 ! tooth +relationship: part_of MA:0001906 ! lower jaw + +[Term] +id: MA:0001908 +name: upper jaw +xref: EMAPS:1792428 +relationship: part_of MA:0001905 ! jaw + +[Term] +id: MA:0001909 +name: upper jaw tooth +xref: EMAPS:1793828 +is_a: MA:0000348 ! tooth +relationship: part_of MA:0001908 ! upper jaw + +[Term] +id: MA:0001910 +name: snout +synonym: "muzzle" RELATED [] +xref: EMAPS:3280628 +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0001911 +name: ocular refractive media +is_a: MA:0002450 ! body fluid or substance +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0001912 +name: upper respiratory tract epithelium +xref: EMAPS:3589428 +is_a: MA:0001480 ! respiratory tract epithelium +relationship: part_of MA:0000442 ! upper respiratory tract + +[Term] +id: MA:0001913 +name: alveolar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001914 +name: suprarenal artery +alt_id: MA:0002055 +synonym: "adrenal artery" RELATED [] +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001915 +name: anterior cerebral artery +xref: EMAPS:1785428 +is_a: MA:0002562 ! cerebral artery + +[Term] +id: MA:0001916 +name: artery of lower lip +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001917 +name: artery of upper lip +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001918 +name: auricular artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001919 +name: maxillary artery +alt_id: MA:0001995 +xref: EMAPS:1731128 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001920 +name: basilar artery +xref: EMAPS:1730728 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001921 +name: brachial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001922 +name: brachiocephalic trunk +alt_id: MA:0001980 +synonym: "innominate artery" RELATED [] +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001923 +name: bronchial artery +xref: EMAPS:1860828 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001924 +name: buccal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001925 +name: carotid artery +xref: EMAPS:1860928 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001926 +name: common carotid artery +xref: EMAPS:1785528 +is_a: MA:0001925 ! carotid artery + +[Term] +id: MA:0001927 +name: left common carotid artery +xref: EMAPS:3549128 +is_a: MA:0001926 ! common carotid artery + +[Term] +id: MA:0001928 +name: right common carotid artery +xref: EMAPS:3574928 +is_a: MA:0001926 ! common carotid artery + +[Term] +id: MA:0001929 +name: external carotid artery +xref: EMAPS:1861128 +is_a: MA:0001925 ! carotid artery + +[Term] +id: MA:0001930 +name: internal carotid artery +xref: EMAPS:1632828 +is_a: MA:0001925 ! carotid artery + +[Term] +id: MA:0001931 +name: celiac artery +synonym: "coeliac artery" RELATED [] +xref: EMAPS:3520228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001933 +name: cerebellar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001934 +name: superior cerebellar artery +xref: EMAPS:1930928 +is_a: MA:0001933 ! cerebellar artery + +[Term] +id: MA:0001935 +name: middle cerebral artery +xref: EMAPS:1823928 +is_a: MA:0002562 ! cerebral artery + +[Term] +id: MA:0001936 +name: cervical artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001937 +name: cervical trunk +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001938 +name: communicating artery +xref: EMAPS:1859828 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001939 +name: costo-cervical trunk +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001940 +name: deferent duct artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001941 +name: digital artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001942 +name: dorsal artery of foot +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001943 +name: dorsal intercostal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001944 +name: dorsal metacarpal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001945 +name: dorsal nasal artery +xref: EMAPS:3529228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001946 +name: dorsal penis artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001947 +name: ductus arteriosis +xref: EMAPS:1785828 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001948 +name: epigastric artery +xref: EMAPS:1875028 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001949 +name: ethmoidal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001950 +name: facial artery +xref: EMAPS:1921328 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001951 +name: femoral artery +xref: EMAPS:3534228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001952 +name: medial femoral artery +is_a: MA:0001951 ! femoral artery + +[Term] +id: MA:0001953 +name: forelimb digital arteries +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001954 +name: forelimb common dorsal digital arteries +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001955 +name: median dorsal digital artery for digit 01 +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001956 +name: lateral dorsal digital artery for digit 05 +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001957 +name: common palmar digital arteries +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001958 +name: forelimb proper dorsal digital arteries +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001959 +name: proper palmar digital arteries +is_a: MA:0001953 ! forelimb digital arteries + +[Term] +id: MA:0001960 +name: frontal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001961 +name: gastric artery +xref: EMAPS:3537428 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001962 +name: gastroepiploic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001963 +name: hepatic artery +xref: EMAPS:1785928 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001964 +name: hindlimb digital arteries +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001965 +name: hindlimb common dorsal digital arteries +is_a: MA:0001964 ! hindlimb digital arteries + +[Term] +id: MA:0001966 +name: common plantar digital arteries +is_a: MA:0001964 ! hindlimb digital arteries + +[Term] +id: MA:0001967 +name: hindlimb proper dorsal digital arteries +is_a: MA:0001964 ! hindlimb digital arteries + +[Term] +id: MA:0001968 +name: proper plantar digital arteries +is_a: MA:0001964 ! hindlimb digital arteries + +[Term] +id: MA:0001969 +name: hyoid artery +xref: EMAPS:1730828 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001970 +name: ileocolic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001971 +name: iliac artery +xref: EMAPS:1730928 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001972 +name: common iliac artery +alt_id: MA:0001932 +xref: EMAPS:1731028 +is_a: MA:0001971 ! iliac artery + +[Term] +id: MA:0001973 +name: external iliac artery +xref: EMAPS:1761428 +is_a: MA:0001971 ! iliac artery + +[Term] +id: MA:0001974 +name: internal iliac artery +xref: EMAPS:1786028 +is_a: MA:0001971 ! iliac artery + +[Term] +id: MA:0001975 +name: iliac circumflex artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001976 +name: ilio-lumbar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001977 +name: infraorbital artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001978 +name: inferior epigastric artery +xref: EMAPS:1875128 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001979 +name: inferior rectal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001981 +name: intercostal artery +xref: EMAPS:1875328 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001982 +name: internal mammary artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001983 +name: internal spermatic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001984 +name: internal thoracic artery +xref: EMAPS:1861728 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001985 +name: intersegmental artery +xref: EMAPS:1761628 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001986 +name: kidney subcortical arteries +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001987 +name: labial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001988 +name: lacrimal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001989 +name: lateral thoracic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001990 +name: lieno-gastric artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001991 +name: lienal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001992 +name: lingual artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001993 +name: major palatine artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001994 +name: maternal placental artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001996 +name: medial femoral circumflex artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001997 +name: medial plantar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001998 +name: medial tarsal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0001999 +name: median artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002000 +name: median artery palmar branch +is_a: MA:0001999 ! median artery + +[Term] +id: MA:0002001 +name: meningeal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002002 +name: mental artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002003 +name: mesenteric artery +xref: EMAPS:1731228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002004 +name: inferior mesenteric artery +xref: EMAPS:1861828 +is_a: MA:0002003 ! mesenteric artery + +[Term] +id: MA:0002005 +name: superior mesenteric artery +xref: EMAPS:1861928 +is_a: MA:0002003 ! mesenteric artery + +[Term] +id: MA:0002006 +name: middle caudal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002007 +name: middle colic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002008 +name: obturator artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002009 +name: occipital artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002010 +name: ocular angle artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002011 +name: ophthalmic artery +xref: EMAPS:1700728 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002012 +name: ovarian artery +xref: EMAPS:1862028 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002013 +name: pancreatico-duodenal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002014 +name: inferior pancreatico-duodenal artery +is_a: MA:0002013 ! pancreatico-duodenal artery + +[Term] +id: MA:0002015 +name: superior pancreatico-duodenal artery +is_a: MA:0002013 ! pancreatico-duodenal artery + +[Term] +id: MA:0002016 +name: pericardiacoophrenic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002017 +name: perineal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002018 +name: peroneal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002019 +name: phrenic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002020 +name: pial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002021 +name: popliteal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002022 +name: posterior cerebral artery +xref: EMAPS:1786128 +is_a: MA:0002562 ! cerebral artery + +[Term] +id: MA:0002023 +name: posterior communicating artery +xref: EMAPS:1860028 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002024 +name: principal artery to forelimb +xref: EMAPS:1681128 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002025 +name: principal artery to hindlimb +xref: EMAPS:1681228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002026 +name: profunda brachii artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002027 +name: profunda femoris artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002028 +name: pudendal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002029 +name: superior external pudendal artery +is_a: MA:0002028 ! pudendal artery + +[Term] +id: MA:0002030 +name: pudic-epigastric trunk +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002031 +name: pulmonary artery +xref: EMAPS:1700828 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002032 +name: left pulmonary artery +is_a: MA:0002031 ! pulmonary artery + +[Term] +id: MA:0002033 +name: pulmonary trunk +xref: EMAPS:1824028 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002034 +name: radial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002035 +name: renal artery +xref: EMAPS:1786228 +xref: EMAPS:2837328 +is_a: MA:0000064 ! artery +is_a: MA:0002578 ! kidney arterial blood vessel + +[Term] +id: MA:0002036 +name: left renal artery +is_a: MA:0002035 ! renal artery + +[Term] +id: MA:0002037 +name: right renal artery +is_a: MA:0002035 ! renal artery + +[Term] +id: MA:0002038 +name: retinal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002039 +name: saphenous artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002040 +name: spermatic artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002041 +name: left spermatic artery +is_a: MA:0002040 ! spermatic artery + +[Term] +id: MA:0002042 +name: right spermatic artery +is_a: MA:0002040 ! spermatic artery + +[Term] +id: MA:0002043 +name: spinal artery +xref: EMAPS:1824128 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002044 +name: stapedial artery +xref: EMAPS:1731328 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002045 +name: subclavian artery +xref: EMAPS:1761728 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002046 +name: left subclavian artery +is_a: MA:0002045 ! subclavian artery + +[Term] +id: MA:0002047 +name: right subclavian artery +is_a: MA:0002045 ! subclavian artery + +[Term] +id: MA:0002048 +name: subcostal artery +xref: EMAPS:1909728 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002049 +name: sublingual artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002050 +name: subscapular artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002051 +name: superficial antebrachial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002052 +name: superficial cervical artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002053 +name: superficial radial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002054 +name: superior gluteal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002056 +name: inferior suprarenal artery +is_a: MA:0001914 ! suprarenal artery + +[Term] +id: MA:0002057 +name: superior suprarenal artery +is_a: MA:0001914 ! suprarenal artery + +[Term] +id: MA:0002058 +name: sural artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002059 +name: external sural artery +is_a: MA:0002058 ! sural artery + +[Term] +id: MA:0002060 +name: superficial sural artery +is_a: MA:0002058 ! sural artery + +[Term] +id: MA:0002061 +name: temporal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002062 +name: superficial temporal artery +is_a: MA:0002061 ! temporal artery + +[Term] +id: MA:0002063 +name: testicular artery +xref: EMAPS:1862128 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002064 +name: thoraco-acromial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002065 +name: thoracodorsal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002066 +name: thyroid artery +xref: EMAPS:1862228 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002067 +name: tibial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002068 +name: transverse facial artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002069 +name: ulnar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002070 +name: ulnar artery palmar branch +is_a: MA:0002069 ! ulnar artery + +[Term] +id: MA:0002071 +name: ulnar collateral artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002072 +name: umbilical artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002073 +name: upper intercostal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002074 +name: ureteric artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002075 +name: ventral intercostal artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002076 +name: ventral nasal artery +xref: EMAPS:3590928 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002077 +name: vertebral artery +xref: EMAPS:1731428 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002078 +name: vesical artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002079 +name: inferior vesical artery +is_a: MA:0002078 ! vesical artery + +[Term] +id: MA:0002080 +name: superior vesical artery +is_a: MA:0002078 ! vesical artery + +[Term] +id: MA:0002081 +name: adrenal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002082 +name: anastomotic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002083 +name: anterior auricular vein +is_a: MA:0003054 ! auricular vein + +[Term] +id: MA:0002084 +name: axillary vein +xref: EMAPS:1875828 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002085 +name: azygos vein +xref: EMAPS:1825028 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002086 +name: basilic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002087 +name: brachial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002088 +name: bronchial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002089 +name: buccal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002090 +name: caudal auricular vein +is_a: MA:0003054 ! auricular vein + +[Term] +id: MA:0002091 +name: caudal humeral circumflex vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002092 +name: cephalic vein +xref: EMAPS:2507528 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002093 +name: cerebellar vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002094 +name: inferior cerebellar vein +is_a: MA:0002093 ! cerebellar vein + +[Term] +id: MA:0002095 +name: superior cerebellar vein +is_a: MA:0002093 ! cerebellar vein + +[Term] +id: MA:0002096 +name: cerebral vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002097 +name: inferior cerebral vein +is_a: MA:0002096 ! cerebral vein + +[Term] +id: MA:0002098 +name: cutaneous vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002099 +name: deep iliac circumflex vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002100 +name: deferent duct vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002101 +name: digital vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002102 +name: dorsal cerebellar vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002103 +name: dorsal cerebral vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002104 +name: dorsal intercostal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002105 +name: dorsal metatarsal vein +alt_id: MA:0002135 +is_a: MA:0002133 ! hindlimb digital veins + +[Term] +id: MA:0002106 +name: dorsal nasal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002107 +name: dorsal penis vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002108 +name: dorsal spinal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002109 +name: dorsal vena of penis +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002110 +name: dorsal venous arch +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002111 +name: ductus venosus +xref: EMAPS:1734328 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002112 +name: duodenal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002113 +name: dural vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002114 +name: epigastric vein +xref: EMAPS:1875928 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002115 +name: facial vein +xref: EMAPS:1922028 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002116 +name: anterior facial vein +is_a: MA:0002115 ! facial vein + +[Term] +id: MA:0002117 +name: posterior facial vein +is_a: MA:0002115 ! facial vein + +[Term] +id: MA:0002118 +name: femoral vein +xref: EMAPS:1787628 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002119 +name: medial femoral vein +alt_id: MA:0002170 +is_a: MA:0002118 ! femoral vein + +[Term] +id: MA:0002120 +name: forelimb digital veins +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002121 +name: common palmar digital vein +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002122 +name: digital torus vein +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002123 +name: forelimb common dorsal digital vein +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002124 +name: forelimb proper dorsal digital vein +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002125 +name: lateral dorsal digital vein 05 +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002126 +name: proper palmar vein +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002127 +name: superficial palmar arch +is_a: MA:0002120 ! forelimb digital veins + +[Term] +id: MA:0002128 +name: gastric vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002129 +name: gastroepiploic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002131 +name: great vein of heart +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002132 +name: hepatic portal vein +is_a: MA:0002198 ! portal vein + +[Term] +id: MA:0002133 +name: hindlimb digital veins +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002134 +name: common plantar vein +is_a: MA:0002133 ! hindlimb digital veins + +[Term] +id: MA:0002136 +name: hindlimb common dorsal digital vein +is_a: MA:0002133 ! hindlimb digital veins + +[Term] +id: MA:0002137 +name: hindlimb proper dorsal digital vein +is_a: MA:0002133 ! hindlimb digital veins + +[Term] +id: MA:0002138 +name: proper plantar vein +is_a: MA:0002133 ! hindlimb digital veins + +[Term] +id: MA:0002139 +name: hypogastric vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002140 +name: ileal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002141 +name: ileocolic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002142 +name: iliac vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002143 +name: common iliac vein +xref: EMAPS:1787428 +is_a: MA:0002142 ! iliac vein + +[Term] +id: MA:0002144 +name: external iliac vein +is_a: MA:0002142 ! iliac vein + +[Term] +id: MA:0002145 +name: internal iliac vein +is_a: MA:0002142 ! iliac vein + +[Term] +id: MA:0002146 +name: ilio-lumbar vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002147 +name: inferior palpebral vein +synonym: "lower palpebral vein" RELATED [] +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002148 +name: internal mammary vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002149 +name: internal spermatic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002150 +name: left internal spermatic vein +is_a: MA:0002149 ! internal spermatic vein + +[Term] +id: MA:0002151 +name: right internal spermatic vein +is_a: MA:0002149 ! internal spermatic vein + +[Term] +id: MA:0002152 +name: ischiatic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002153 +name: jejunal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002154 +name: jugular vein +xref: EMAPS:1863828 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002155 +name: anterior jugular vein +is_a: MA:0002154 ! jugular vein + +[Term] +id: MA:0002156 +name: external jugular vein +xref: EMAPS:1787528 +is_a: MA:0002154 ! jugular vein + +[Term] +id: MA:0002157 +name: internal jugular vein +xref: EMAPS:1762028 +is_a: MA:0002154 ! jugular vein + +[Term] +id: MA:0002158 +name: kidney subcortical veins +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002159 +name: lateral caudal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002160 +name: lateral marginal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002161 +name: lateral saphenous vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002162 +name: lateral thoracic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002163 +name: left hepatico-cardiac vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002164 +name: lienal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002165 +name: lieno-pancreatic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002166 +name: linguofacial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002167 +name: masseteric vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002168 +name: maternal placental vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002169 +name: maxillary vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002171 +name: medial marginal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002172 +name: medial plantar vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002173 +name: medial saphenous vein +is_a: MA:0002215 ! saphenous vein + +[Term] +id: MA:0002174 +name: medial tarsal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002175 +name: median vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002176 +name: median cubital vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002177 +name: mesenteric vein +xref: EMAPS:1734828 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002178 +name: inferior mesenteric vein +xref: EMAPS:1864228 +is_a: MA:0002177 ! mesenteric vein + +[Term] +id: MA:0002179 +name: superior mesenteric vein +xref: EMAPS:1864328 +is_a: MA:0002177 ! mesenteric vein + +[Term] +id: MA:0002180 +name: middle caudal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002181 +name: middle colic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002182 +name: naso-frontal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002183 +name: obturator vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002184 +name: ocular angle vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002185 +name: ophthalmic plexus +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002186 +name: ovarian vein +xref: EMAPS:1864428 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002187 +name: pericardiacophrenic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002189 +name: pancreatic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002190 +name: pancreatico-duodenal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002191 +name: inferior pancreatico-duodenal vein +is_a: MA:0002190 ! pancreatico-duodenal vein + +[Term] +id: MA:0002192 +name: superior pancreatico-duodenal vein +is_a: MA:0002190 ! pancreatico-duodenal vein + +[Term] +id: MA:0002193 +name: perineal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002194 +name: phrenic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002195 +name: inferior phrenic vein +is_a: MA:0002194 ! phrenic vein + +[Term] +id: MA:0002196 +name: pial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002197 +name: popliteal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002198 +name: portal vein +xref: EMAPS:1734928 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002199 +name: principal vein of forelimb +xref: EMAPS:1701828 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002200 +name: principal vein of hindlimb +xref: EMAPS:1701928 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002201 +name: proximal caudal femoral vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002202 +name: pudendal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002203 +name: inferior external pudendal vein +is_a: MA:0002202 ! pudendal vein + +[Term] +id: MA:0002204 +name: superior external pudendal vein +is_a: MA:0002202 ! pudendal vein + +[Term] +id: MA:0002205 +name: pudendoepigastric vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002206 +name: pulmonary vein +xref: EMAPS:1864528 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002207 +name: left pulmonary vein +is_a: MA:0002206 ! pulmonary vein + +[Term] +id: MA:0002208 +name: right pulmonary vein +is_a: MA:0002206 ! pulmonary vein + +[Term] +id: MA:0002209 +name: right hepatico-cardiac vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002210 +name: renal vein +xref: EMAPS:2837628 +is_a: MA:0000067 ! vein +is_a: MA:0002591 ! kidney venous blood vessel + +[Term] +id: MA:0002211 +name: left renal vein +is_a: MA:0002210 ! renal vein + +[Term] +id: MA:0002212 +name: right renal vein +is_a: MA:0002210 ! renal vein + +[Term] +id: MA:0002213 +name: retinal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002214 +name: rostral auricular vein +is_a: MA:0003054 ! auricular vein + +[Term] +id: MA:0002215 +name: saphenous vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002216 +name: great saphenous vein +alt_id: MA:0002130 +is_a: MA:0002215 ! saphenous vein + +[Term] +id: MA:0002217 +name: small saphenous vein +is_a: MA:0002215 ! saphenous vein + +[Term] +id: MA:0002218 +name: spermatic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002219 +name: left spermatic vein +is_a: MA:0002218 ! spermatic vein + +[Term] +id: MA:0002220 +name: right spermatic vein +is_a: MA:0002218 ! spermatic vein + +[Term] +id: MA:0002221 +name: subclavian vein +xref: EMAPS:1762128 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002222 +name: subcostal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002223 +name: submental vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002224 +name: subscapular vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002225 +name: superficial cervical vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002226 +name: superior intercostal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002227 +name: superior vesical vein +alt_id: MA:0002265 +xref: EMAPS:1864628 +is_a: MA:0002263 ! vesical vein + +[Term] +id: MA:0002228 +name: supraorbital vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002229 +name: suprarenal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002230 +name: inferior suprarenal vein +is_a: MA:0002229 ! suprarenal vein + +[Term] +id: MA:0002231 +name: sural vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002232 +name: external sural vein +is_a: MA:0002231 ! sural vein + +[Term] +id: MA:0002233 +name: tail vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002234 +name: testicular vein +xref: EMAPS:1864728 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002235 +name: thoracic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002236 +name: external thoracic vein +is_a: MA:0002235 ! thoracic vein + +[Term] +id: MA:0002237 +name: internal thoracic vein +xref: EMAPS:1864128 +is_a: MA:0002235 ! thoracic vein + +[Term] +id: MA:0002238 +name: thoracodorsal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002239 +name: temporal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002240 +name: deep temporal vein +is_a: MA:0002239 ! temporal vein + +[Term] +id: MA:0002241 +name: middle temporal vein +is_a: MA:0002239 ! temporal vein + +[Term] +id: MA:0002242 +name: superficial temporal vein +xref: EMAPS:1931528 +is_a: MA:0002239 ! temporal vein + +[Term] +id: MA:0002243 +name: tibial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002244 +name: anterior tibial vein +is_a: MA:0002243 ! tibial vein + +[Term] +id: MA:0002245 +name: posterior tibial vein +is_a: MA:0002243 ! tibial vein + +[Term] +id: MA:0002246 +name: thymic vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002247 +name: transverse facial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002248 +name: ulnar collateral vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002249 +name: umbilical vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002250 +name: ureteric vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002251 +name: vaginal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002252 +name: vein of clitoris +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002253 +name: vein of lower lip +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002254 +name: vein of trabecular bone +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002255 +name: vein of upper lip +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002256 +name: vein of vesicular gland +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002257 +name: venous vaginal plexus +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002258 +name: ventral auricular vein +is_a: MA:0003054 ! auricular vein + +[Term] +id: MA:0002259 +name: ventral intercostal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002260 +name: ventral labial vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002261 +name: ventral nasal vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002262 +name: vertebral vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002263 +name: vesical vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0002264 +name: inferior vesical vein +is_a: MA:0002263 ! vesical vein + +[Term] +id: MA:0002266 +name: abductor pollicis longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002267 +name: adductor group (leg) +xref: EMAPS:1916628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002268 +name: anterior abdominal wall muscle +xref: EMAPS:1774428 +xref: EMAPS:1774528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002269 +name: biceps brachii +xref: EMAPS:1910828 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002270 +name: biceps femoris +xref: EMAPS:3517028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002271 +name: brachialis +xref: EMAPS:1910928 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002272 +name: buccinator +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002273 +name: bulboglandular +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002274 +name: cleidobrachial +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002275 +name: cleidocephalic +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002276 +name: cleidooccipital +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002277 +name: coccygeus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002278 +name: constrictor muscle of pharynx +xref: EMAPS:1896428 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002279 +name: constrictor muscle of pharynx inferior +xref: EMAPS:1896528 +is_a: MA:0002278 ! constrictor muscle of pharynx + +[Term] +id: MA:0002280 +name: constrictor muscle of pharynx superior +xref: EMAPS:1896628 +is_a: MA:0002278 ! constrictor muscle of pharynx + +[Term] +id: MA:0002281 +name: constrictor vulvae +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002282 +name: coracobrachial +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002283 +name: cricoarytenoid +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002284 +name: cricothyroid +xref: EMAPS:1927028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002285 +name: cutaneous trunci +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002286 +name: deltoid +xref: EMAPS:1817728 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002287 +name: depressor labii inferioris +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002288 +name: digastric +xref: EMAPS:2513428 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002289 +name: erector spinae +xref: EMAPS:1816828 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002290 +name: extensor carpi radialis brevis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002291 +name: extensor carpi radialis longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002292 +name: extensor carpi ulnaris +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002293 +name: extensor digitorum communis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002294 +name: extensor digitorum lateralis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002295 +name: extensor digitorum longus +xref: EMAPS:3533028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002296 +name: extrinsic tongue muscle +xref: EMAPS:1888028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002297 +name: flexor carpi radialis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002298 +name: flexor carpi ulnaris +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002299 +name: flexor digitorum longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002300 +name: flexor digitorum profundus +xref: EMAPS:1931928 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002301 +name: flexor hallucis longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002302 +name: foot interosseus muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002303 +name: dorsal foot interosseus muscle +is_a: MA:0002302 ! foot interosseus muscle + +[Term] +id: MA:0002304 +name: plantar foot interosseus muscle +is_a: MA:0002302 ! foot interosseus muscle + +[Term] +id: MA:0002305 +name: foot lumbrical muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002306 +name: gastrocnemius +xref: EMAPS:3537528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002307 +name: genioglossus +xref: EMAPS:1827628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002308 +name: geniohyoid +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002309 +name: gluteus maximus +synonym: "gluteus superficialis" RELATED [] +xref: EMAPS:1852728 +is_a: MA:0000535 ! gluteal muscle + +[Term] +id: MA:0002310 +name: gluteus medius +xref: EMAPS:1916328 +is_a: MA:0000535 ! gluteal muscle + +[Term] +id: MA:0002311 +name: gracilis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002312 +name: hamstring muscle +xref: EMAPS:1914528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002313 +name: hand interosseous muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002314 +name: dorsal hand interosseus muscle +is_a: MA:0002313 ! hand interosseous muscle + +[Term] +id: MA:0002315 +name: palmar hand interosseus muscle +is_a: MA:0002313 ! hand interosseous muscle + +[Term] +id: MA:0002316 +name: hand lumbrical muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002317 +name: hyoglossus +xref: EMAPS:1827728 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002318 +name: iliacus +xref: EMAPS:1916428 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002319 +name: iliocostalis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002320 +name: iliocostalis thoracis +is_a: MA:0002319 ! iliocostalis + +[Term] +id: MA:0002321 +name: iliopsoas +xref: EMAPS:1852028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002322 +name: iliothoracic +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002323 +name: infraspinatus +xref: EMAPS:1852628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002324 +name: intercostales +synonym: "intercostal muscle" RELATED [] +xref: EMAPS:3543628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002325 +name: intercostales externus +synonym: "intercostal muscle external layer" RELATED [] +xref: EMAPS:1852228 +is_a: MA:0002324 ! intercostales + +[Term] +id: MA:0002326 +name: intercostales internus +synonym: "intercostal muscle internal layer" RELATED [] +xref: EMAPS:1852328 +is_a: MA:0002324 ! intercostales + +[Term] +id: MA:0002327 +name: intrinsic tongue muscle +xref: EMAPS:1888528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002328 +name: intrinsic tongue muscle transverse component +xref: EMAPS:1888628 +relationship: part_of MA:0002327 ! intrinsic tongue muscle + +[Term] +id: MA:0002329 +name: intrinsic tongue muscle vertical component +xref: EMAPS:1888728 +relationship: part_of MA:0002327 ! intrinsic tongue muscle + +[Term] +id: MA:0002330 +name: ischiocavernosus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002331 +name: latissimus dorsi +xref: EMAPS:1817828 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002332 +name: levator ani +xref: EMAPS:1916528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002333 +name: levator labii superioris +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002334 +name: levator nasolabialis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002335 +name: longissimus atlantis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002336 +name: longissimus capitis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002337 +name: longissimus cervicis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002338 +name: longissimus lumborum +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002339 +name: longissimus thoracis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002340 +name: longus capitis +xref: EMAPS:2513128 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002341 +name: longus colli +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002342 +name: lumbosacrocaudalis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002343 +name: masseter +xref: EMAPS:2513528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002344 +name: mylohyoid +xref: EMAPS:2513628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002345 +name: obliquus externus abdominis +xref: EMAPS:1816228 +is_a: MA:0003024 ! oblique abdominal muscle + +[Term] +id: MA:0002346 +name: obliquus internus abdominis +xref: EMAPS:1816328 +is_a: MA:0003024 ! oblique abdominal muscle + +[Term] +id: MA:0002347 +name: obturator externus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002348 +name: omohyoid +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002349 +name: omotransverse +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002351 +name: palatoglossus +xref: EMAPS:1827828 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002352 +name: parotidoauricular +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002353 +name: pectineus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002354 +name: pectoralis major +xref: EMAPS:1817928 +is_a: MA:0002423 ! pectoralis muscle + +[Term] +id: MA:0002355 +name: pectoralis minor +xref: EMAPS:1818028 +is_a: MA:0002423 ! pectoralis muscle + +[Term] +id: MA:0002356 +name: peroneus longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002357 +name: pronator teres +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002358 +name: psoas major +xref: EMAPS:1816928 +is_a: MA:0002553 ! psoas muscle + +[Term] +id: MA:0002359 +name: psoas minor +xref: EMAPS:1817028 +is_a: MA:0002553 ! psoas muscle + +[Term] +id: MA:0002360 +name: pterygoid lateralis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002361 +name: pterygoid medialis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002362 +name: quadratus lumborum +xref: EMAPS:1852428 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002363 +name: quadriceps +synonym: "quadriceps femoris" RELATED [] +xref: EMAPS:1914628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002364 +name: rectus abdominis +xref: EMAPS:1816428 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002365 +name: rectus femoris +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002366 +name: rectus thoracis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002367 +name: rhomboid +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002368 +name: sartorius +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002369 +name: scalenus dorsalis +synonym: "scalenus posterior" RELATED [] +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002370 +name: scalenus medius +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002371 +name: semimembranosus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002372 +name: semispinalis capitis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002373 +name: semispinalis cervicis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002374 +name: semispinalis thoracis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002375 +name: semitendinosus +xref: EMAPS:3576228 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002376 +name: serratus dorsalis caudalis +synonym: "serratus posterior inferior" RELATED [] +is_a: MA:0003025 ! serratus muscle + +[Term] +id: MA:0002377 +name: serratus dorsalis cranialis +synonym: "serratus posterior superior" RELATED [] +is_a: MA:0003025 ! serratus muscle + +[Term] +id: MA:0002378 +name: serratus ventralis +synonym: "serratus anterior" RELATED [] +is_a: MA:0003025 ! serratus muscle + +[Term] +id: MA:0002380 +name: sphincter colli superficialis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002381 +name: spinalis thoracis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002382 +name: splenius +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002383 +name: sternohyoid +xref: EMAPS:1927228 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002384 +name: sternomastoid +xref: EMAPS:2513728 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002385 +name: sternooccipital +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002386 +name: sternothyroid +xref: EMAPS:1927228 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002387 +name: styloglossus +xref: EMAPS:1827928 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002388 +name: subscapularis +xref: EMAPS:1818128 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002389 +name: supraspinatus +xref: EMAPS:1818228 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002390 +name: temporalis +xref: EMAPS:2513828 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002391 +name: tensor fasciae lata +xref: EMAPS:3585528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002392 +name: teres major +xref: EMAPS:1911028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002393 +name: thyrohyoid +xref: EMAPS:1927328 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002394 +name: tibialis caudalis +synonym: "tibialis posterior" RELATED [] +is_a: MA:0002425 ! tibialis muscle + +[Term] +id: MA:0002395 +name: tibialis cranialis +synonym: "tibialis anterior" RELATED [] +xref: EMAPS:3586628 +is_a: MA:0002425 ! tibialis muscle + +[Term] +id: MA:0002396 +name: transversus abdominis +xref: EMAPS:1816528 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002397 +name: transversus thoracis +xref: EMAPS:1926728 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002398 +name: trapezius +xref: EMAPS:1818328 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002399 +name: triceps brachii +xref: EMAPS:1911128 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002400 +name: triceps surae +synonym: "sural triceps" RELATED [] +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002401 +name: urethralis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002402 +name: vastus lateralis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002403 +name: vastus medialis +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002404 +name: zygomaticus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002405 +name: postnatal mouse +synonym: "adult mouse" RELATED [] +synonym: "TS28 mouse" RELATED [] +xref: EMAPS:2576528 +is_a: MA:0003000 ! anatomical structure + +[Term] +id: MA:0002406 +name: ganglion +xref: EMAPS:3284628 +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0002407 +name: nerve plexus +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0002408 +name: nerve trunk +relationship: part_of MA:0000016 ! nervous system + +[Term] +id: MA:0002409 +name: lower respiratory tract connective tissue +relationship: part_of MA:0000435 ! lower respiratory tract + +[Term] +id: MA:0002410 +name: lower respiratory tract smooth muscle +xref: EMAPS:3552028 +relationship: part_of MA:0000435 ! lower respiratory tract + +[Term] +id: MA:0002411 +name: exocrine system +xref: EMAPS:3532928 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0002412 +name: soft palate +xref: EMAPS:1894928 +relationship: part_of MA:0000341 ! oral region +relationship: part_of MA:0002476 ! palate + +[Term] +id: MA:0002413 +name: olfactory lobe +xref: EMAPS:1777828 +relationship: part_of MA:0000183 ! telencephalon + +[Term] +id: MA:0002414 +name: cumulus oophorus +xref: EMAPS:3526728 +relationship: part_of MA:0001460 ! ovary stratum granulosum + +[Term] +id: MA:0002415 +name: exocrine pancreas +xref: EMAPS:3532828 +is_a: MA:0002564 ! exocrine gland +relationship: part_of MA:0000120 ! pancreas + +[Term] +id: MA:0002416 +name: vertebral column +xref: EMAPS:3591928 +is_a: MA:0000494 ! back bone +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0002417 +name: pancreatic acinus +xref: EMAPS:3565128 +relationship: part_of MA:0002415 ! exocrine pancreas + +[Term] +id: MA:0002418 +name: musculoskeletal system +xref: EMAPS:3271428 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0002419 +name: pancreatic islet core +synonym: "beta cell islet" RELATED [] +xref: EMAPS:3565328 +relationship: part_of MA:0000127 ! pancreatic islet + +[Term] +id: MA:0002420 +name: gonad +xref: EMAPS:1738328 +is_a: MA:0001752 ! reproductive organ + +[Term] +id: MA:0002421 +name: pancreatic islet mantle +xref: EMAPS:3565428 +relationship: part_of MA:0000127 ! pancreatic islet + +[Term] +id: MA:0002422 +name: prostate gland anterior lobe +xref: EMAPS:2979428 +is_a: MA:0001738 ! prostate gland lobe + +[Term] +id: MA:0002423 +name: pectoralis muscle +xref: EMAPS:3567028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002424 +name: soleus +xref: EMAPS:3578628 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002425 +name: tibialis muscle +xref: EMAPS:3586728 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002426 +name: hypothalamic nucleus +xref: EMAPS:3541728 +relationship: part_of MA:0000173 ! hypothalamus + +[Term] +id: MA:0002427 +name: hippocampus layer +xref: EMAPS:3540728 +relationship: part_of MA:0000191 ! hippocampus + +[Term] +id: MA:0002428 +name: hippocampus region +xref: EMAPS:3277228 +relationship: part_of MA:0000191 ! hippocampus + +[Term] +id: MA:0002429 +name: dentate gyrus layer +xref: EMAPS:3527828 +relationship: part_of MA:0000190 ! dentate gyrus + +[Term] +id: MA:0002430 +name: cerebellum white matter +xref: EMAPS:3523528 +is_a: MA:0000820 ! brain white matter +relationship: part_of MA:0000198 ! cerebellum + +[Term] +id: MA:0002431 +name: digestive system +is_a: MA:0000019 ! visceral organ system + +[Term] +id: MA:0002432 +name: oculomotor muscle +is_a: MA:0001271 ! extraocular skeletal muscle + +[Term] +id: MA:0002433 +name: anatomic region +is_a: MA:0003000 ! anatomical structure +relationship: part_of MA:0002405 ! postnatal mouse + +[Term] +id: MA:0002434 +name: hematopoietic system +synonym: "haematopoietic system" RELATED [] +synonym: "hemopoietic system" RELATED [] +xref: EMAPS:3540228 +relationship: part_of MA:0000013 ! hemolymphoid system + +[Term] +id: MA:0002435 +name: lymphoid system +relationship: part_of MA:0000013 ! hemolymphoid system +relationship: part_of MA:0002711 ! immune system + +[Term] +id: MA:0002436 +name: lymphoid tissue +relationship: part_of MA:0002435 ! lymphoid system + +[Term] +id: MA:0002437 +name: muscle tissue +xref: EMAPS:3271528 +is_a: MA:0003002 ! tissue +relationship: part_of MA:0002888 ! muscular system + +[Term] +id: MA:0002438 +name: striated muscle tissue +is_a: MA:0002437 ! muscle tissue + +[Term] +id: MA:0002439 +name: skeletal muscle tissue +xref: EMAPS:3271628 +is_a: MA:0002438 ! striated muscle tissue +relationship: part_of MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002441 +name: cardiac muscle tissue +xref: EMAPS:3268828 +is_a: MA:0002438 ! striated muscle tissue +relationship: part_of MA:0000164 ! myocardium + +[Term] +id: MA:0002442 +name: sensory organ system +xref: EMAPS:1619228 +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0002443 +name: auditory system +is_a: MA:0002442 ! sensory organ system + +[Term] +id: MA:0002444 +name: visual system +is_a: MA:0002442 ! sensory organ system + +[Term] +id: MA:0002445 +name: olfactory system +is_a: MA:0002442 ! sensory organ system + +[Term] +id: MA:0002446 +name: gustatory system +is_a: MA:0002442 ! sensory organ system + +[Term] +id: MA:0002447 +name: body cavity +is_a: MA:0000005 ! body cavity or lining + +[Term] +id: MA:0002448 +name: cavity lining +is_a: MA:0000005 ! body cavity or lining + +[Term] +id: MA:0002449 +name: heart/pericardium +is_a: MA:0000557 ! thoracic cavity organ + +[Term] +id: MA:0002450 +name: body fluid or substance +xref: EMAPS:3517828 +is_a: MA:0003000 ! anatomical structure +relationship: part_of MA:0002405 ! postnatal mouse + +[Term] +id: MA:0002451 +name: eye skin gland +is_a: MA:0000146 ! skin gland +is_a: MA:0000267 ! eye gland + +[Term] +id: MA:0002452 +name: sebaceous gland of eye +is_a: MA:0002451 ! eye skin gland +is_a: MA:0002565 ! sebaceous gland + +[Term] +id: MA:0002453 +name: coronary artery +xref: EMAPS:1916028 +is_a: MA:0000064 ! artery +is_a: MA:0002483 ! heart blood vessel + +[Term] +id: MA:0002454 +name: left coronary artery +is_a: MA:0002453 ! coronary artery + +[Term] +id: MA:0002455 +name: right coronary artery +is_a: MA:0002453 ! coronary artery + +[Term] +id: MA:0002456 +name: septal coronary artery +is_a: MA:0002453 ! coronary artery + +[Term] +id: MA:0002457 +name: lung blood vessel +xref: EMAPS:3286728 +is_a: MA:0000554 ! thoracic cavity blood vessel +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0002458 +name: scala media +xref: EMAPS:3575128 +is_a: MA:0000248 ! perilymphatic channel + +[Term] +id: MA:0002459 +name: eye chamber +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0002460 +name: eye posterior chamber +is_a: MA:0002459 ! eye chamber +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0002461 +name: vitreous chamber +is_a: MA:0002459 ! eye chamber +relationship: part_of MA:0002485 ! eye posterior segment + +[Term] +id: MA:0002462 +name: vitreous body +relationship: part_of MA:0002461 ! vitreous chamber + +[Term] +id: MA:0002463 +name: carotid body +xref: EMAPS:1921128 +is_a: MA:0001925 ! carotid artery + +[Term] +id: MA:0002464 +name: labium +xref: EMAPS:3083728 +relationship: part_of MA:0000395 ! vulva + +[Term] +id: MA:0002465 +name: vaginal hymen +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0002466 +name: perineum +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0002467 +name: periodontal ligament +synonym: "periodontal membrane" RELATED [] +synonym: "periodontium" RELATED [] +xref: EMAPS:3567928 +is_a: MA:0003005 ! skeletal ligament + +[Term] +id: MA:0002468 +name: ear lobe +synonym: "ear lobule" RELATED [] +synonym: "lobule of auricle" RELATED [] +synonym: "lobule of pinna" RELATED [] +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0002469 +name: parasympathetic ganglion +xref: EMAPS:3281328 +is_a: MA:0000220 ! autonomic ganglion + +[Term] +id: MA:0002470 +name: submandibular ganglion +synonym: "lingual ganglion" RELATED [] +synonym: "maxillary ganglion" RELATED [] +synonym: "submaxillary ganglion" RELATED [] +is_a: MA:0002469 ! parasympathetic ganglion + +[Term] +id: MA:0002471 +name: retina photoreceptor layer inner segment +xref: EMAPS:3568728 +relationship: part_of MA:0001308 ! retina photoreceptor layer + +[Term] +id: MA:0002472 +name: retina photoreceptor layer outer segment +xref: EMAPS:3568828 +relationship: part_of MA:0001308 ! retina photoreceptor layer + +[Term] +id: MA:0002473 +name: face +xref: EMAPS:3276328 +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0002474 +name: mouth +relationship: part_of MA:0001910 ! snout + +[Term] +id: MA:0002475 +name: cheek +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0002476 +name: palate +xref: EMAPS:1894828 +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0002477 +name: hard palate +xref: EMAPS:1895228 +relationship: part_of MA:0002476 ! palate + +[Term] +id: MA:0002478 +name: major salivary gland +is_a: MA:0000346 ! salivary gland + +[Term] +id: MA:0002479 +name: minor salivary gland +xref: EMAPS:3557428 +is_a: MA:0000346 ! salivary gland + +[Term] +id: MA:0002480 +name: uvea +xref: EMAPS:3590128 +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0002481 +name: fat pad +xref: EMAPS:3534028 +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0002482 +name: orbit +relationship: part_of MA:0000316 ! cranium +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0002483 +name: heart blood vessel +xref: EMAPS:3539728 +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0002484 +name: eye anterior segment +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0002485 +name: eye posterior segment +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0002486 +name: eye surface +xref: EMAPS:3533628 +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0002487 +name: spleen pulp +xref: EMAPS:3580528 +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0002488 +name: parietal pleura +xref: EMAPS:1677628 +is_a: MA:0000433 ! pleura + +[Term] +id: MA:0002489 +name: visceral pleura +xref: EMAPS:1677728 +is_a: MA:0000433 ! pleura + +[Term] +id: MA:0002490 +name: urinary bladder muscularis mucosa +xref: EMAPS:2861928 +relationship: part_of MA:0001695 ! urinary bladder lamina propria + +[Term] +id: MA:0002491 +name: urinary bladder neck +relationship: part_of MA:0000380 ! urinary bladder + +[Term] +id: MA:0002492 +name: urinary bladder trigone +xref: EMAPS:3517428 +relationship: part_of MA:0000380 ! urinary bladder + +[Term] +id: MA:0002493 +name: urinary bladder wall +xref: EMAPS:3517528 +relationship: part_of MA:0000380 ! urinary bladder + +[Term] +id: MA:0002494 +name: liver lobule +xref: EMAPS:3549928 +relationship: part_of MA:0000366 ! liver parenchyma + +[Term] +id: MA:0002495 +name: bile canaliculus +relationship: part_of MA:0002494 ! liver lobule + +[Term] +id: MA:0002496 +name: liver acinus +xref: EMAPS:3549728 +relationship: part_of MA:0002494 ! liver lobule + +[Term] +id: MA:0002497 +name: liver perisinusoidal space +relationship: part_of MA:0002494 ! liver lobule + +[Term] +id: MA:0002498 +name: portal lobule +relationship: part_of MA:0000366 ! liver parenchyma + +[Term] +id: MA:0002499 +name: portal triad +relationship: part_of MA:0000366 ! liver parenchyma + +[Term] +id: MA:0002500 +name: right pulmonary artery +is_a: MA:0002031 ! pulmonary artery + +[Term] +id: MA:0002501 +name: plasma +xref: EMAPS:3569028 +relationship: part_of MA:0000059 ! blood + +[Term] +id: MA:0002502 +name: serum +xref: EMAPS:3577028 +relationship: part_of MA:0002501 ! plasma + +[Term] +id: MA:0002503 +name: cerebrospinal fluid +synonym: "CSF" RELATED [] +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002504 +name: exocrine gland fluid/secretion +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002505 +name: mammary gland fluid/secretion +is_a: MA:0002504 ! exocrine gland fluid/secretion + +[Term] +id: MA:0002506 +name: cerumen +is_a: MA:0002504 ! exocrine gland fluid/secretion + +[Term] +id: MA:0002507 +name: saliva +is_a: MA:0002504 ! exocrine gland fluid/secretion + +[Term] +id: MA:0002508 +name: tear +is_a: MA:0002504 ! exocrine gland fluid/secretion + +[Term] +id: MA:0002509 +name: feces +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002510 +name: female reproductive system fluid/secretion +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002511 +name: ovary follicle fluid +is_a: MA:0002510 ! female reproductive system fluid/secretion + +[Term] +id: MA:0002512 +name: digestive system fluid or secretion +is_a: MA:0002450 ! body fluid or substance +relationship: part_of MA:0002431 ! digestive system + +[Term] +id: MA:0002513 +name: bile +is_a: MA:0002512 ! digestive system fluid or secretion + +[Term] +id: MA:0002514 +name: esophagus secretion +is_a: MA:0002512 ! digestive system fluid or secretion + +[Term] +id: MA:0002515 +name: intestine secretion +is_a: MA:0002512 ! digestive system fluid or secretion + +[Term] +id: MA:0002516 +name: pancreas secretion +is_a: MA:0002512 ! digestive system fluid or secretion + +[Term] +id: MA:0002517 +name: endocrine pancreas secretion +is_a: MA:0002516 ! pancreas secretion + +[Term] +id: MA:0002518 +name: exocrine pancreas secretion +is_a: MA:0002516 ! pancreas secretion + +[Term] +id: MA:0002519 +name: stomach secretion +synonym: "gastric juice" RELATED [] +is_a: MA:0002512 ! digestive system fluid or secretion + +[Term] +id: MA:0002520 +name: lymph +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002521 +name: male reproductive system fluid/secretion +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002522 +name: semen +is_a: MA:0002521 ! male reproductive system fluid/secretion + +[Term] +id: MA:0002523 +name: seminal fluid +relationship: part_of MA:0002522 ! semen + +[Term] +id: MA:0002524 +name: bulbourethral gland secretion +relationship: part_of MA:0002523 ! seminal fluid + +[Term] +id: MA:0002525 +name: prostate gland secretion +relationship: part_of MA:0002523 ! seminal fluid + +[Term] +id: MA:0002526 +name: seminal vesicle secretion +relationship: part_of MA:0002523 ! seminal fluid + +[Term] +id: MA:0002527 +name: otolymph +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002528 +name: endolymph +is_a: MA:0002527 ! otolymph + +[Term] +id: MA:0002529 +name: perilymph +is_a: MA:0002527 ! otolymph + +[Term] +id: MA:0002530 +name: pericardial fluid +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002531 +name: peritoneal fluid +xref: EMAPS:3568328 +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002532 +name: pleural fluid +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002533 +name: respiratory system fluid/secretion +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002534 +name: lung surfactant +is_a: MA:0002533 ! respiratory system fluid/secretion + +[Term] +id: MA:0002535 +name: nasal mucus +is_a: MA:0002533 ! respiratory system fluid/secretion + +[Term] +id: MA:0002536 +name: sputum +is_a: MA:0002533 ! respiratory system fluid/secretion + +[Term] +id: MA:0002537 +name: skin fluid/secretion +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002538 +name: sebum +is_a: MA:0002537 ! skin fluid/secretion + +[Term] +id: MA:0002539 +name: sweat +is_a: MA:0002537 ! skin fluid/secretion + +[Term] +id: MA:0002540 +name: tooth substance +xref: EMAPS:3587228 +is_a: MA:0002450 ! body fluid or substance +relationship: part_of MA:0000348 ! tooth + +[Term] +id: MA:0002541 +name: cementum +xref: EMAPS:3520328 +is_a: MA:0002540 ! tooth substance + +[Term] +id: MA:0002542 +name: dentin +xref: EMAPS:3528128 +is_a: MA:0002540 ! tooth substance + +[Term] +id: MA:0002543 +name: enamel +xref: EMAPS:3530328 +is_a: MA:0002540 ! tooth substance +relationship: part_of MA:0001604 ! tooth enamel organ + +[Term] +id: MA:0002544 +name: synovial fluid +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002545 +name: urine +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002546 +name: juxtaglomerular complex +synonym: "juxtaglomerular apparatus" RELATED [] +xref: EMAPS:3044928 +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002547 +name: gonadal fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0002548 +name: inguinal fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0002549 +name: retroperitoneal fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0002550 +name: epididymal fat pad +xref: EMAPS:3531628 +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0002551 +name: colostrum +is_a: MA:0002505 ! mammary gland fluid/secretion + +[Term] +id: MA:0002552 +name: mammary gland milk +is_a: MA:0002505 ! mammary gland fluid/secretion + +[Term] +id: MA:0002553 +name: psoas muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002554 +name: popliteus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002555 +name: scaphoid +synonym: "navicular of hand" RELATED [] +synonym: "radial carpal bone" RELATED [] +relationship: part_of MA:0001346 ! scapholunate + +[Term] +id: MA:0002556 +name: lunate +synonym: "intermediate carpal bone" RELATED [] +synonym: "semilunar" RELATED [] +relationship: part_of MA:0001346 ! scapholunate + +[Term] +id: MA:0002557 +name: proximal carpal bone +is_a: MA:0000296 ! carpal bone + +[Term] +id: MA:0002558 +name: distal carpal bone +is_a: MA:0000296 ! carpal bone + +[Term] +id: MA:0002559 +name: stomach body +synonym: "gastric corpus" RELATED [] +xref: EMAPS:3581028 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0002560 +name: stomach pyloric region +synonym: "pylorus" RELATED [] +xref: EMAPS:1763128 +is_a: MA:0002561 ! stomach region + +[Term] +id: MA:0002561 +name: stomach region +xref: EMAPS:3582128 +relationship: part_of MA:0000353 ! stomach + +[Term] +id: MA:0002562 +name: cerebral artery +xref: EMAPS:1861328 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002563 +name: endocrine gland +xref: EMAPS:3599928 +is_a: MA:0003038 ! gland +relationship: part_of MA:0000012 ! endocrine system + +[Term] +id: MA:0002564 +name: exocrine gland +xref: EMAPS:3532728 +is_a: MA:0003038 ! gland +relationship: part_of MA:0002411 ! exocrine system + +[Term] +id: MA:0002565 +name: sebaceous gland +xref: EMAPS:3575428 +is_a: MA:0000146 ! skin gland +is_a: MA:0003042 ! holocrine gland + +[Term] +id: MA:0002566 +name: sensory ganglion +is_a: MA:0001161 ! peripheral nervous system ganglion + +[Term] +id: MA:0002567 +name: corpora quadrigemina +relationship: part_of MA:0000211 ! tectum + +[Term] +id: MA:0002568 +name: alveolar wall +xref: EMAPS:3512028 +relationship: part_of MA:0000420 ! lung alveolus + +[Term] +id: MA:0002569 +name: thoracic aorta +xref: EMAPS:1860328 +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0002570 +name: ascending aorta +xref: EMAPS:1701428 +relationship: part_of MA:0002569 ! thoracic aorta + +[Term] +id: MA:0002571 +name: descending aorta +xref: EMAPS:1860628 +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0002572 +name: descending thoracic aorta +xref: EMAPS:1860528 +relationship: part_of MA:0002569 ! thoracic aorta +relationship: part_of MA:0002571 ! descending aorta + +[Term] +id: MA:0002573 +name: axillary artery +xref: EMAPS:1874928 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002574 +name: anterior tibial artery +is_a: MA:0002067 ! tibial artery + +[Term] +id: MA:0002575 +name: posterior tibial artery +is_a: MA:0002067 ! tibial artery + +[Term] +id: MA:0002576 +name: atrioventricular bundle +synonym: "bundle of his" RELATED [] +synonym: "his bundle" RELATED [] +xref: EMAPS:3515228 +relationship: part_of MA:0000094 ! impulse conducting system + +[Term] +id: MA:0002577 +name: pre-botzinger complex +synonym: "pre-botzinger respiratory control center" RELATED [] +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0002578 +name: kidney arterial blood vessel +xref: EMAPS:3143628 +is_a: MA:0001682 ! kidney blood vessel + +[Term] +id: MA:0002579 +name: afferent arteriole +xref: EMAPS:2826628 +is_a: MA:0002578 ! kidney arterial blood vessel +relationship: part_of MA:0000376 ! renal corpuscle + +[Term] +id: MA:0002580 +name: part of afferent arteriole forming juxtaglomerular complex +synonym: "renin-producing cells" RELATED [] +xref: EMAPS:2826928 +relationship: part_of MA:0002546 ! juxtaglomerular complex +relationship: part_of MA:0002579 ! afferent arteriole + +[Term] +id: MA:0002581 +name: rest of afferent arteriole +xref: EMAPS:2827228 +relationship: part_of MA:0002579 ! afferent arteriole + +[Term] +id: MA:0002582 +name: kidney cortex artery +synonym: "renal cortex arterial system" RELATED [] +synonym: "renal cortex artery" RELATED [] +xref: EMAPS:2814728 +is_a: MA:0002578 ! kidney arterial blood vessel +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002583 +name: arcuate artery +xref: EMAPS:2821528 +is_a: MA:0002582 ! kidney cortex artery + +[Term] +id: MA:0002584 +name: interlobular artery +xref: EMAPS:2821228 +is_a: MA:0002582 ! kidney cortex artery + +[Term] +id: MA:0002585 +name: efferent arteriole +xref: EMAPS:2827528 +is_a: MA:0002578 ! kidney arterial blood vessel +relationship: part_of MA:0000376 ! renal corpuscle + +[Term] +id: MA:0002586 +name: kidney capillary +xref: EMAPS:3144328 +is_a: MA:0001682 ! kidney blood vessel + +[Term] +id: MA:0002587 +name: glomerular capillary +synonym: "glomerular capillary system" RELATED [] +xref: EMAPS:2824528 +is_a: MA:0002586 ! kidney capillary +relationship: part_of MA:0001657 ! glomerulus + +[Term] +id: MA:0002588 +name: peritubular capillary +is_a: MA:0002586 ! kidney capillary + +[Term] +id: MA:0002589 +name: kidney outer medulla peritubular capillary +xref: EMAPS:3546128 +is_a: MA:0002588 ! peritubular capillary +relationship: part_of MA:0001653 ! kidney outer medulla + +[Term] +id: MA:0002590 +name: kidney cortex peritubular capillary +synonym: "renal cortex peritubular capillary" RELATED [] +is_a: MA:0002588 ! peritubular capillary +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002591 +name: kidney venous blood vessel +xref: EMAPS:3145028 +is_a: MA:0001682 ! kidney blood vessel + +[Term] +id: MA:0002592 +name: kidney cortex vein +synonym: "renal cortex vein" RELATED [] +synonym: "renal cortex venous system" RELATED [] +xref: EMAPS:2815228 +is_a: MA:0002591 ! kidney venous blood vessel +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002593 +name: arcuate vein +xref: EMAPS:2822128 +is_a: MA:0002592 ! kidney cortex vein + +[Term] +id: MA:0002594 +name: interlobular vein +xref: EMAPS:2821828 +is_a: MA:0002592 ! kidney cortex vein + +[Term] +id: MA:0002595 +name: renal medullary capillary +synonym: "vasa recta" RELATED [] +xref: EMAPS:3004328 +is_a: MA:0002586 ! kidney capillary + +[Term] +id: MA:0002596 +name: inner renal medulla vasa recta +is_a: MA:0002595 ! renal medullary capillary +relationship: part_of MA:0001652 ! kidney inner medulla + +[Term] +id: MA:0002597 +name: kidney outer medulla vasa recta +is_a: MA:0002595 ! renal medullary capillary +relationship: part_of MA:0001653 ! kidney outer medulla + +[Term] +id: MA:0002598 +name: kidney inner medulla collecting duct +synonym: "papillary collecting duct" RELATED [] +xref: EMAPS:2837028 +is_a: MA:0002935 ! kidney medulla collecting duct +relationship: part_of MA:0001652 ! kidney inner medulla + +[Term] +id: MA:0002599 +name: kidney outer medulla collecting duct +xref: EMAPS:2834628 +is_a: MA:0002935 ! kidney medulla collecting duct +relationship: part_of MA:0001653 ! kidney outer medulla + +[Term] +id: MA:0002600 +name: kidney cortex collecting duct +synonym: "renal cortex collecting duct" RELATED [] +xref: EMAPS:2813028 +is_a: MA:0000371 ! kidney collecting duct +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002601 +name: ureteric tip +xref: EMAPS:2774928 +is_a: MA:0000371 ! kidney collecting duct + +[Term] +id: MA:0002602 +name: extraglomerular mesangium +xref: EMAPS:2827828 +relationship: part_of MA:0000376 ! renal corpuscle +relationship: part_of MA:0002546 ! juxtaglomerular complex +relationship: part_of MA:0002617 ! mesangium + +[Term] +id: MA:0002603 +name: macula densa +xref: EMAPS:2839928 +relationship: part_of MA:0002546 ! juxtaglomerular complex + +[Term] +id: MA:0002604 +name: distal straight tubule macula densa +xref: EMAPS:2839928 +relationship: part_of MA:0001677 ! loop of henle ascending limb thick segment +relationship: part_of MA:0002603 ! macula densa +relationship: part_of MA:0002609 ! kidney cortex tubule + +[Term] +id: MA:0002605 +name: glomerular parietal epithelium +xref: EMAPS:3596928 +is_a: MA:0002847 ! kidney glomerular epithelium +relationship: part_of MA:0001660 ! glomerular capsule + +[Term] +id: MA:0002606 +name: glomerular mesangium +relationship: part_of MA:0001657 ! glomerulus +relationship: part_of MA:0002617 ! mesangium + +[Term] +id: MA:0002607 +name: glomerular visceral epithelium +synonym: "podocyte layer" RELATED [] +xref: EMAPS:3597028 +is_a: MA:0002847 ! kidney glomerular epithelium +relationship: part_of MA:0001657 ! glomerulus + +[Term] +id: MA:0002608 +name: kidney cortex interstitium +synonym: "renal cortex interstitium" RELATED [] +xref: EMAPS:2813628 +relationship: part_of MA:0000372 ! kidney cortex +relationship: part_of MA:0002616 ! kidney interstitium + +[Term] +id: MA:0002609 +name: kidney cortex tubule +synonym: "cortical tubule" RELATED [] +synonym: "renal cortex tubule" RELATED [] +xref: EMAPS:1897628 +is_a: MA:0000377 ! kidney tubule +relationship: part_of MA:0000372 ! kidney cortex + +[Term] +id: MA:0002610 +name: kidney connecting tubule +xref: EMAPS:2801128 +is_a: MA:0002609 ! kidney cortex tubule + +[Term] +id: MA:0002611 +name: kidney proximal tubule +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0002612 +name: proximal tubule segment 1 +xref: EMAPS:2965728 +is_a: MA:0002611 ! kidney proximal tubule +relationship: part_of MA:0001669 ! proximal convoluted tubule + +[Term] +id: MA:0002613 +name: proximal tubule segment 2 +xref: EMAPS:2965928 +is_a: MA:0002611 ! kidney proximal tubule +relationship: part_of MA:0001669 ! proximal convoluted tubule + +[Term] +id: MA:0002614 +name: proximal straight tubule +synonym: "pars recta" RELATED [] +synonym: "proximal tubule segment 3" RELATED [] +xref: EMAPS:2966928 +is_a: MA:0002611 ! kidney proximal tubule +is_a: MA:0002634 ! kidney straight tubule +is_a: MA:0002995 ! kidney medulla tubule +relationship: part_of MA:0001679 ! loop of henle descending limb +relationship: part_of MA:0002630 ! outer medulla outer stripe loop of henle + +[Term] +id: MA:0002615 +name: distal straight tubule postmacula segment +xref: EMAPS:2840228 +relationship: part_of MA:0001677 ! loop of henle ascending limb thick segment +relationship: part_of MA:0002609 ! kidney cortex tubule + +[Term] +id: MA:0002616 +name: kidney interstitium +xref: EMAPS:2851828 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0002617 +name: mesangium +relationship: part_of MA:0002616 ! kidney interstitium + +[Term] +id: MA:0002618 +name: perihilar interstitium +xref: EMAPS:2808328 +relationship: part_of MA:0000374 ! kidney pelvis +relationship: part_of MA:0002616 ! kidney interstitium + +[Term] +id: MA:0002619 +name: kidney medulla interstitium +xref: EMAPS:1832628 +relationship: part_of MA:0002616 ! kidney interstitium + +[Term] +id: MA:0002620 +name: kidney inner medulla interstitium +xref: EMAPS:2836428 +relationship: part_of MA:0001652 ! kidney inner medulla +relationship: part_of MA:0002619 ! kidney medulla interstitium + +[Term] +id: MA:0002621 +name: kidney outer medulla interstitium +xref: EMAPS:2833728 +relationship: part_of MA:0001653 ! kidney outer medulla +relationship: part_of MA:0002619 ! kidney medulla interstitium + +[Term] +id: MA:0002622 +name: kidney subcapsular mesenchyme +relationship: part_of MA:0002616 ! kidney interstitium + +[Term] +id: MA:0002623 +name: kidney inner medulla loop of henle +xref: EMAPS:2835228 +is_a: MA:0002995 ! kidney medulla tubule +relationship: part_of MA:0001652 ! kidney inner medulla + +[Term] +id: MA:0002624 +name: loop of henle bend +xref: EMAPS:2835828 +relationship: part_of MA:0001675 ! loop of henle +relationship: part_of MA:0002623 ! kidney inner medulla loop of henle + +[Term] +id: MA:0002625 +name: loop of henle thin descending limb +xref: EMAPS:2968128 +is_a: MA:0002995 ! kidney medulla tubule +relationship: part_of MA:0001679 ! loop of henle descending limb +relationship: part_of MA:0002623 ! kidney inner medulla loop of henle +relationship: part_of MA:0002627 ! outer medulla inner stripe loop of henle + +[Term] +id: MA:0002626 +name: outer medulla inner stripe +xref: EMAPS:2967528 +relationship: part_of MA:0001653 ! kidney outer medulla + +[Term] +id: MA:0002627 +name: outer medulla inner stripe loop of henle +xref: EMAPS:2967928 +relationship: part_of MA:0002626 ! outer medulla inner stripe + +[Term] +id: MA:0002628 +name: distal straight tubule premacula segment +xref: EMAPS:2967128 +is_a: MA:0002995 ! kidney medulla tubule +relationship: part_of MA:0001677 ! loop of henle ascending limb thick segment +relationship: part_of MA:0002627 ! outer medulla inner stripe loop of henle +relationship: part_of MA:0002630 ! outer medulla outer stripe loop of henle + +[Term] +id: MA:0002629 +name: outer medulla outer stripe +xref: EMAPS:2966328 +relationship: part_of MA:0001653 ! kidney outer medulla + +[Term] +id: MA:0002630 +name: outer medulla outer stripe loop of henle +xref: EMAPS:2966528 +relationship: part_of MA:0002629 ! outer medulla outer stripe + +[Term] +id: MA:0002631 +name: kidney pelvis smooth muscle +xref: EMAPS:2812028 +relationship: part_of MA:0000374 ! kidney pelvis + +[Term] +id: MA:0002632 +name: kidney pelvis urothelium +xref: EMAPS:2807728 +relationship: part_of MA:0000374 ! kidney pelvis + +[Term] +id: MA:0002633 +name: kidney distal tubule +xref: EMAPS:2838728 +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0002634 +name: kidney straight tubule +is_a: MA:0000377 ! kidney tubule + +[Term] +id: MA:0002635 +name: renal nerve +xref: EMAPS:2969128 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0002636 +name: lower urinary tract +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0002637 +name: female urethra +xref: EMAPS:2874728 +is_a: MA:0000379 ! urethra + +[Term] +id: MA:0002638 +name: female membranous urethra +relationship: part_of MA:0002637 ! female urethra +relationship: part_of MA:0002647 ! membranous urethra + +[Term] +id: MA:0002639 +name: female urethral meatus +relationship: part_of MA:0002637 ! female urethra + +[Term] +id: MA:0002640 +name: male urethra +xref: EMAPS:1869228 +is_a: MA:0000379 ! urethra + +[Term] +id: MA:0002641 +name: male membranous urethra +relationship: part_of MA:0002640 ! male urethra +relationship: part_of MA:0002647 ! membranous urethra + +[Term] +id: MA:0002642 +name: male urethra ostium +relationship: part_of MA:0002640 ! male urethra + +[Term] +id: MA:0002643 +name: penile urethra +xref: EMAPS:3094428 +relationship: part_of MA:0002640 ! male urethra + +[Term] +id: MA:0002644 +name: penile urethra cavernous portion +relationship: part_of MA:0002643 ! penile urethra + +[Term] +id: MA:0002645 +name: penile urethra fossa terminalis +relationship: part_of MA:0002643 ! penile urethra + +[Term] +id: MA:0002646 +name: prostatic urethra +xref: EMAPS:3094228 +relationship: part_of MA:0002640 ! male urethra + +[Term] +id: MA:0002647 +name: membranous urethra +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0002648 +name: urethra mesenchymal layer +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0002649 +name: urethra muscle +synonym: "urethral muscle layer" RELATED [] +relationship: part_of MA:0000379 ! urethra + +[Term] +id: MA:0002650 +name: urethral sphincter +relationship: part_of MA:0002636 ! lower urinary tract + +[Term] +id: MA:0002651 +name: rest of ureter +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002652 +name: ureter adventitia +xref: EMAPS:2811428 +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002653 +name: ureter lamina propria +xref: EMAPS:2884128 +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002654 +name: ureter muscle layer +xref: EMAPS:2884428 +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002655 +name: ureter urothelium +synonym: "ureter transitional epithelium" RELATED [] +xref: EMAPS:2808928 +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002656 +name: ureter luminal urothelium +relationship: part_of MA:0002655 ! ureter urothelium + +[Term] +id: MA:0002657 +name: ureter subluminal urothelium +relationship: part_of MA:0002655 ! ureter urothelium + +[Term] +id: MA:0002658 +name: ureteral valve +relationship: part_of MA:0000378 ! ureter + +[Term] +id: MA:0002659 +name: bile duct extrahepatic part +relationship: part_of MA:0000354 ! bile duct + +[Term] +id: MA:0002660 +name: common hepatic duct +relationship: part_of MA:0001636 ! hepatic duct extrahepatic part + +[Term] +id: MA:0002661 +name: extrahepatic bile duct epithelium +relationship: part_of MA:0001629 ! bile duct epithelium +relationship: part_of MA:0002659 ! bile duct extrahepatic part + +[Term] +id: MA:0002662 +name: intrahepatic bile duct epithelium +relationship: part_of MA:0001629 ! bile duct epithelium +relationship: part_of MA:0001630 ! bile duct intrahepatic part + +[Term] +id: MA:0002663 +name: intrahepatic part of left hepatic duct +xref: EMAPS:1830428 +relationship: part_of MA:0001637 ! hepatic duct intrahepatic part +relationship: part_of MA:0001638 ! left hepatic duct + +[Term] +id: MA:0002664 +name: intrahepatic part of right hepatic duct +xref: EMAPS:1830528 +relationship: part_of MA:0001637 ! hepatic duct intrahepatic part +relationship: part_of MA:0001639 ! right hepatic duct + +[Term] +id: MA:0002665 +name: hilar part of hepatic duct +relationship: part_of MA:0001636 ! hepatic duct extrahepatic part + +[Term] +id: MA:0002666 +name: hilar part of left hepatic duct +relationship: part_of MA:0001638 ! left hepatic duct +relationship: part_of MA:0002665 ! hilar part of hepatic duct + +[Term] +id: MA:0002667 +name: hilar part of right hepatic duct +relationship: part_of MA:0001639 ! right hepatic duct +relationship: part_of MA:0002665 ! hilar part of hepatic duct + +[Term] +id: MA:0002668 +name: interlobular bile duct +relationship: part_of MA:0001630 ! bile duct intrahepatic part +relationship: part_of MA:0002499 ! portal triad + +[Term] +id: MA:0002669 +name: intralobular bile duct +synonym: "canal of hering" RELATED [] +synonym: "canal of herring" RELATED [] +relationship: part_of MA:0001630 ! bile duct intrahepatic part +relationship: part_of MA:0002494 ! liver lobule + +[Term] +id: MA:0002670 +name: spleen hilum +xref: EMAPS:1930328 +relationship: part_of MA:0000141 ! spleen + +[Term] +id: MA:0002671 +name: splenic cord +relationship: part_of MA:0000756 ! spleen red pulp + +[Term] +id: MA:0002672 +name: spleen lymphoid follicle +synonym: "spleen lymphoid nodule" RELATED [] +xref: EMAPS:3580428 +relationship: part_of MA:0000762 ! spleen white pulp + +[Term] +id: MA:0002673 +name: thymus lymphoid tissue +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0002674 +name: thymus trabecula +relationship: part_of MA:0000142 ! thymus + +[Term] +id: MA:0002675 +name: thyroid gland capsule +relationship: part_of MA:0000129 ! thyroid gland + +[Term] +id: MA:0002676 +name: parathyroid gland capsule +xref: EMAPS:3566328 +relationship: part_of MA:0000128 ! parathyroid gland + +[Term] +id: MA:0002677 +name: parathyroid gland parenchyma +xref: EMAPS:3566428 +relationship: part_of MA:0000128 ! parathyroid gland + +[Term] +id: MA:0002678 +name: filiform papilla +xref: EMAPS:1887328 +is_a: MA:0001593 ! tongue papilla + +[Term] +id: MA:0002679 +name: foliate papilla +xref: EMAPS:3278828 +is_a: MA:0001593 ! tongue papilla + +[Term] +id: MA:0002680 +name: esophagus mucosa +xref: EMAPS:2698128 +relationship: part_of MA:0002691 ! esophagus wall + +[Term] +id: MA:0002681 +name: esophagus muscularis mucosa +xref: EMAPS:2698928 +relationship: part_of MA:0002680 ! esophagus mucosa + +[Term] +id: MA:0002682 +name: esophagus muscle +xref: EMAPS:2698328 +relationship: part_of MA:0002691 ! esophagus wall + +[Term] +id: MA:0002683 +name: stomach mucosa +xref: EMAPS:3581728 +is_a: MA:0001521 ! gastrointestinal system mucosa +relationship: part_of MA:0002692 ! stomach wall + +[Term] +id: MA:0002684 +name: stomach muscularis mucosa +xref: EMAPS:3581828 +relationship: part_of MA:0002683 ! stomach mucosa + +[Term] +id: MA:0002685 +name: stomach submucosa +xref: EMAPS:3582528 +relationship: part_of MA:0002692 ! stomach wall + +[Term] +id: MA:0002686 +name: small intestine mucosa +xref: EMAPS:3578028 +relationship: part_of MA:0001537 ! intestine mucosa +relationship: part_of MA:0002696 ! small intestine wall + +[Term] +id: MA:0002687 +name: small intestine muscularis mucosa +xref: EMAPS:3578128 +relationship: part_of MA:0002686 ! small intestine mucosa +relationship: part_of MA:0002694 ! intestine muscularis mucosa + +[Term] +id: MA:0002688 +name: large intestine mucosa +xref: EMAPS:3546728 +relationship: part_of MA:0001537 ! intestine mucosa +relationship: part_of MA:0002695 ! large intestine wall + +[Term] +id: MA:0002689 +name: large intestine muscularis mucosa +relationship: part_of MA:0002688 ! large intestine mucosa +relationship: part_of MA:0002694 ! intestine muscularis mucosa + +[Term] +id: MA:0002690 +name: large intestine submucosa +relationship: part_of MA:0002695 ! large intestine wall + +[Term] +id: MA:0002691 +name: esophagus wall +xref: EMAPS:3532628 +relationship: part_of MA:0000352 ! esophagus + +[Term] +id: MA:0002692 +name: stomach wall +xref: EMAPS:3582628 +relationship: part_of MA:0000353 ! stomach + +[Term] +id: MA:0002693 +name: intestine wall +xref: EMAPS:3544428 +relationship: part_of MA:0000328 ! intestine + +[Term] +id: MA:0002694 +name: intestine muscularis mucosa +xref: EMAPS:3544228 +relationship: part_of MA:0001537 ! intestine mucosa + +[Term] +id: MA:0002695 +name: large intestine wall +xref: EMAPS:3547028 +relationship: part_of MA:0000333 ! large intestine +relationship: part_of MA:0002693 ! intestine wall + +[Term] +id: MA:0002696 +name: small intestine wall +xref: EMAPS:3578528 +relationship: part_of MA:0000337 ! small intestine + +[Term] +id: MA:0002697 +name: parotid duct +is_a: MA:0001586 ! salivary duct +relationship: part_of MA:0001585 ! parotid gland + +[Term] +id: MA:0002698 +name: submandibular duct +xref: EMAPS:3583328 +is_a: MA:0001586 ! salivary duct +relationship: part_of MA:0001589 ! submandibular gland + +[Term] +id: MA:0002699 +name: sublingual duct +is_a: MA:0001586 ! salivary duct +relationship: part_of MA:0001588 ! sublingual gland + +[Term] +id: MA:0002700 +name: anterior buccal gland +is_a: MA:0002479 ! minor salivary gland + +[Term] +id: MA:0002701 +name: anterior lingual gland +is_a: MA:0002479 ! minor salivary gland + +[Term] +id: MA:0002702 +name: eyelash +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0002703 +name: nail +xref: EMAPS:3558028 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0002704 +name: cuticle +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002705 +name: hyponychium +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002706 +name: nail bed +xref: EMAPS:3558128 +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002707 +name: nail matrix +xref: EMAPS:3558228 +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002708 +name: nail plate +xref: EMAPS:3558328 +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002709 +name: proximal nail bed +relationship: part_of MA:0002703 ! nail + +[Term] +id: MA:0002710 +name: skin muscle +xref: EMAPS:3577628 +relationship: part_of MA:0000151 ! skin + +[Term] +id: MA:0002711 +name: immune system +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0002712 +name: barrel cortex +xref: EMAPS:3516328 +relationship: part_of MA:0000908 ! primary somatosensory cortex + +[Term] +id: MA:0002713 +name: testis interstitial tissue +xref: EMAPS:1868728 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0002714 +name: autopod +synonym: "paw" RELATED [] +xref: EMAPS:3272228 +is_a: MA:0002889 ! limb segment + +[Term] +id: MA:0002715 +name: autopod joint +synonym: "paw joint" RELATED [] +xref: EMAPS:3516028 +relationship: part_of MA:0002714 ! autopod + +[Term] +id: MA:0002716 +name: zeugopod +is_a: MA:0002889 ! limb segment + +[Term] +id: MA:0002717 +name: stylopod +is_a: MA:0002889 ! limb segment + +[Term] +id: MA:0002718 +name: vascular system +xref: EMAPS:3590528 +relationship: part_of MA:0000010 ! cardiovascular system + +[Term] +id: MA:0002719 +name: arterial system +xref: EMAPS:1620128 +is_a: MA:0002718 ! vascular system + +[Term] +id: MA:0002720 +name: venous system +xref: EMAPS:1624028 +is_a: MA:0002718 ! vascular system + +[Term] +id: MA:0002721 +name: intercerebral commissure +synonym: "interhemispheric commissure" RELATED [] +xref: EMAPS:3543528 +relationship: part_of MA:0000945 ! cerebral white matter + +[Term] +id: MA:0002722 +name: anterior commissure +xref: EMAPS:1903828 +is_a: MA:0002721 ! intercerebral commissure + +[Term] +id: MA:0002723 +name: hippocampal commissure +xref: EMAPS:3540428 +relationship: part_of MA:0000945 ! cerebral white matter + +[Term] +id: MA:0002724 +name: esophagus submucosa +xref: EMAPS:3532528 +relationship: part_of MA:0002691 ! esophagus wall + +[Term] +id: MA:0002725 +name: pharynx epithelium +xref: EMAPS:1670828 +relationship: part_of MA:0003143 ! pharynx mucosa + +[Term] +id: MA:0002726 +name: glans penis +xref: EMAPS:1898828 +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0002727 +name: penis skin +xref: EMAPS:3567528 +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0002728 +name: larynx submucosa +xref: EMAPS:3547428 +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0002729 +name: larynx submucosa gland +xref: EMAPS:3547528 +relationship: part_of MA:0002728 ! larynx submucosa + +[Term] +id: MA:0002730 +name: kidney papilla +synonym: "renal papilla" RELATED [] +xref: EMAPS:3572728 +relationship: part_of MA:0000374 ! kidney pelvis + +[Term] +id: MA:0002731 +name: endometrium epithelium +xref: EMAPS:3530728 +relationship: part_of MA:0000390 ! endometrium + +[Term] +id: MA:0002732 +name: endometrium glandular epithelium +xref: EMAPS:3530828 +relationship: part_of MA:0002731 ! endometrium epithelium + +[Term] +id: MA:0002733 +name: endometrium luminal epithelium +xref: EMAPS:3530928 +relationship: part_of MA:0002731 ! endometrium epithelium + +[Term] +id: MA:0002734 +name: endometrium stroma +xref: EMAPS:3531028 +relationship: part_of MA:0000390 ! endometrium + +[Term] +id: MA:0002735 +name: myometrium inner circular layer +relationship: part_of MA:0000391 ! myometrium + +[Term] +id: MA:0002736 +name: myometrium outer longitudinal layer +relationship: part_of MA:0000391 ! myometrium + +[Term] +id: MA:0002737 +name: vagina stroma +xref: EMAPS:3590228 +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0002738 +name: fibrous pericardium +xref: EMAPS:1902928 +is_a: MA:0000099 ! pericardium + +[Term] +id: MA:0002739 +name: serous pericardium +xref: EMAPS:1903028 +is_a: MA:0000099 ! pericardium + +[Term] +id: MA:0002740 +name: trigeminal V principal sensory nucleus +synonym: "trigeminal V chief sensory nucleus" RELATED [] +is_a: MA:0001030 ! trigeminal V sensory nucleus + +[Term] +id: MA:0002741 +name: brainstem white matter +xref: EMAPS:3518928 +is_a: MA:0000820 ! brain white matter +relationship: part_of MA:0000169 ! brainstem + +[Term] +id: MA:0002742 +name: cerebellar peduncle +xref: EMAPS:3521328 +is_a: MA:0002430 ! cerebellum white matter +is_a: MA:0002741 ! brainstem white matter + +[Term] +id: MA:0002743 +name: posterior commissure +xref: EMAPS:3569528 +is_a: MA:0002741 ! brainstem white matter + +[Term] +id: MA:0002744 +name: inferior cerebellar peduncle +is_a: MA:0002742 ! cerebellar peduncle + +[Term] +id: MA:0002745 +name: middle cerebellar peduncle +is_a: MA:0002742 ! cerebellar peduncle + +[Term] +id: MA:0002746 +name: superior cerebellar peduncle +is_a: MA:0002742 ! cerebellar peduncle + +[Term] +id: MA:0002747 +name: fornix +xref: EMAPS:3535228 +is_a: MA:0000945 ! cerebral white matter + +[Term] +id: MA:0002748 +name: internal capsule +xref: EMAPS:3543728 +is_a: MA:0000945 ! cerebral white matter + +[Term] +id: MA:0002749 +name: spinal cord dorsal column +relationship: part_of MA:0000910 ! spinal cord white matter + +[Term] +id: MA:0002750 +name: spinal cord lateral column +relationship: part_of MA:0000910 ! spinal cord white matter + +[Term] +id: MA:0002751 +name: spinal cord ventral column +relationship: part_of MA:0000910 ! spinal cord white matter + +[Term] +id: MA:0002752 +name: nucleus approprius +relationship: part_of MA:0001119 ! spinal cord dorsal horn + +[Term] +id: MA:0002753 +name: spinal cord intermediolateral nucleus +relationship: part_of MA:0001126 ! spinal cord intermediate grey + +[Term] +id: MA:0002754 +name: neocortex +synonym: "cerebral cortex" RELATED [] +xref: EMAPS:3284228 +relationship: part_of MA:0000185 ! cerebral cortex + +[Term] +id: MA:0002755 +name: lateral cervical nucleus +is_a: MA:0001120 ! spinal cord basal nucleus + +[Term] +id: MA:0002756 +name: lateral spinal nucleus +is_a: MA:0001120 ! spinal cord basal nucleus + +[Term] +id: MA:0002757 +name: periolivary nucleus +xref: EMAPS:3568028 +relationship: part_of MA:0001026 ! superior olivary nucleus + +[Term] +id: MA:0002758 +name: levator auris longus +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002759 +name: alveolar smooth muscle +xref: EMAPS:3512228 +relationship: part_of MA:0000416 ! alveolar system + +[Term] +id: MA:0002760 +name: mammary gland alveolus +relationship: part_of MA:0000145 ! mammary gland +relationship: part_of MA:0000793 ! mammary gland lobule + +[Term] +id: MA:0002761 +name: saphenous nerve +is_a: MA:0000228 ! peripheral nerve +is_a: MA:0000673 ! leg nerve + +[Term] +id: MA:0002762 +name: caput epididymis +xref: EMAPS:1929128 +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0002763 +name: cauda epididymis +xref: EMAPS:1929228 +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0002764 +name: corpus epididymis +xref: EMAPS:1929328 +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0002765 +name: male germ cell +synonym: "male gamete" RELATED [] +synonym: "sperm" RELATED [] +synonym: "spermatid" RELATED [] +synonym: "spermatocyte" RELATED [] +synonym: "spermatogonium" RELATED [] +synonym: "spermatozoa" RELATED [] +xref: EMAPS:1868628 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0002766 +name: accessory olfactory bulb mitral cell layer +xref: EMAPS:3511128 +relationship: part_of MA:0000966 ! accessory olfactory bulb + +[Term] +id: MA:0002767 +name: lateral globus pallidus +synonym: "globus pallidus external segment" RELATED [] +synonym: "globus pallidus lateral segment" RELATED [] +relationship: part_of MA:0000890 ! globus pallidus + +[Term] +id: MA:0002768 +name: medial globus pallidus +synonym: "entopeduncular nucleus" RELATED [] +synonym: "globus pallidus inernal segment" RELATED [] +synonym: "globus pallidus medial segment" RELATED [] +relationship: part_of MA:0000890 ! globus pallidus + +[Term] +id: MA:0002769 +name: brain vasculature +xref: EMAPS:3518228 +is_a: MA:0000060 ! blood vessel +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0002770 +name: semicircular duct ampulla +xref: EMAPS:3283128 +relationship: part_of MA:0000251 ! semicircular duct + +[Term] +id: MA:0002771 +name: crista ampullaris +synonym: "ampullary crest" RELATED [] +xref: EMAPS:3279128 +relationship: part_of MA:0002770 ! semicircular duct ampulla + +[Term] +id: MA:0002772 +name: alisphenoid bone +synonym: "greater wing of sphenoid bone" RELATED [] +is_a: MA:0001478 ! chondrocranium bone +relationship: part_of MA:0001472 ! sphenoid bone + +[Term] +id: MA:0002773 +name: orbitosphenoid +synonym: "lesser wing of sphenoid bone" RELATED [] +xref: EMAPS:1871928 +is_a: MA:0001478 ! chondrocranium bone +relationship: part_of MA:0001472 ! sphenoid bone + +[Term] +id: MA:0002774 +name: sphenoid bone pterygoid process +synonym: "pterygoid process of sphenoid bone" RELATED [] +relationship: part_of MA:0001472 ! sphenoid bone + +[Term] +id: MA:0002775 +name: dorsal lateral geniculate nucleus +synonym: "dorsal nucleus of lateral geniculate body" RELATED [] +xref: EMAPS:3529028 +relationship: part_of MA:0000869 ! lateral geniculate nucleus + +[Term] +id: MA:0002776 +name: ventral lateral geniculate nucleus +synonym: "ventral nucleus of lateral geniculate body" RELATED [] +xref: EMAPS:3590828 +relationship: part_of MA:0000869 ! lateral geniculate nucleus + +[Term] +id: MA:0002777 +name: iris stroma +synonym: "iridial stroma" RELATED [] +xref: EMAPS:3545128 +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0002778 +name: vestibular ganglion superior part +synonym: "pars superior vestibularis" RELATED [] +relationship: part_of MA:0001086 ! vestibulocochlear VIII ganglion vestibular component + +[Term] +id: MA:0002779 +name: vestibular ganglion inferior part +relationship: part_of MA:0001086 ! vestibulocochlear VIII ganglion vestibular component + +[Term] +id: MA:0002780 +name: bone tissue +xref: EMAPS:3517928 +is_a: MA:0003047 ! skeletal tissue +relationship: part_of MA:0001459 ! bone + +[Term] +id: MA:0002781 +name: lamellar bone +is_a: MA:0002780 ! bone tissue + +[Term] +id: MA:0002782 +name: trabecular bone +synonym: "cancellous bone" RELATED [] +is_a: MA:0002780 ! bone tissue +relationship: part_of MA:0002781 ! lamellar bone + +[Term] +id: MA:0002783 +name: bone marrow cavity +relationship: part_of MA:0001461 ! compact bone + +[Term] +id: MA:0002784 +name: stomach glandular epithelium +xref: EMAPS:1762528 +is_a: MA:0001610 ! stomach epithelium +relationship: part_of MA:0001614 ! stomach glandular region mucosa + +[Term] +id: MA:0002785 +name: prostate duct +relationship: part_of MA:0000404 ! prostate gland + +[Term] +id: MA:0002786 +name: tongue squamous epithelium +is_a: MA:0001592 ! tongue epithelium + +[Term] +id: MA:0002787 +name: tongue keratinized epithelium +is_a: MA:0002786 ! tongue squamous epithelium + +[Term] +id: MA:0002788 +name: glottis +relationship: part_of MA:0000414 ! larynx + +[Term] +id: MA:0002789 +name: atrioventricular valve +xref: EMAPS:3515428 +is_a: MA:0000086 ! heart valve + +[Term] +id: MA:0002790 +name: semilunar valve +xref: EMAPS:3576028 +is_a: MA:0000086 ! heart valve + +[Term] +id: MA:0002791 +name: heart ventricle wall +synonym: "wall of ventricle" RELATED [] +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0002792 +name: tooth cavity +synonym: "cavity of tooth" RELATED [] +synonym: "tooth pulp cavity" RELATED [] +relationship: part_of MA:0000348 ! tooth + +[Term] +id: MA:0002793 +name: helix +relationship: part_of MA:0000259 ! auricle + +[Term] +id: MA:0002794 +name: oral mucosa +synonym: "mouth mucosa" RELATED [] +synonym: "mouth mucous membrane" RELATED [] +synonym: "mucosal lining of mouth" RELATED [] +xref: EMAPS:2693728 +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0002795 +name: coronal suture +xref: EMAPS:1922528 +is_a: MA:0001475 ! cranial suture + +[Term] +id: MA:0002796 +name: frontal suture +synonym: "metopic suture" RELATED [] +xref: EMAPS:3535828 +is_a: MA:0001475 ! cranial suture + +[Term] +id: MA:0002797 +name: lambdoid suture +synonym: "lambdoidal suture" RELATED [] +xref: EMAPS:1922728 +is_a: MA:0001475 ! cranial suture + +[Term] +id: MA:0002798 +name: sagittal suture +xref: EMAPS:1922428 +is_a: MA:0001475 ! cranial suture + +[Term] +id: MA:0002799 +name: uterine artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002800 +name: papillary muscle +synonym: "papillary muscle of ventricle" RELATED [] +synonym: "ventricular papillary muscle" RELATED [] +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0002801 +name: thoracic duct +xref: EMAPS:1931028 +is_a: MA:0000138 ! lymphatic vessel + +[Term] +id: MA:0002802 +name: long bone +xref: EMAPS:3550328 +is_a: MA:0001459 ! bone + +[Term] +id: MA:0002803 +name: long bone diaphysis +synonym: "body of long bone" RELATED [] +synonym: "long bone diaphysis" RELATED [] +synonym: "shaft of long bone" RELATED [] +xref: EMAPS:3550528 +relationship: part_of MA:0002802 ! long bone + +[Term] +id: MA:0002804 +name: stapes base +synonym: "base of stapes" RELATED [] +synonym: "stapes footplate" RELATED [] +relationship: part_of MA:0001217 ! stapes + +[Term] +id: MA:0002805 +name: acromion +xref: EMAPS:2511928 +relationship: part_of MA:0001330 ! scapula + +[Term] +id: MA:0002806 +name: scapula spine +synonym: "scapular spine" RELATED [] +relationship: part_of MA:0001330 ! scapula + +[Term] +id: MA:0002807 +name: humerus diaphysis +is_a: MA:0002803 ! long bone diaphysis +relationship: part_of MA:0001356 ! humerus + +[Term] +id: MA:0002808 +name: deltoid tuberosity +xref: EMAPS:2505228 +relationship: part_of MA:0002807 ! humerus diaphysis + +[Term] +id: MA:0002809 +name: cochlear labyrinth +relationship: part_of MA:0000240 ! cochlea +relationship: part_of MA:0000242 ! membranous labyrinth + +[Term] +id: MA:0002810 +name: zygomatic arch +relationship: part_of MA:0001478 ! chondrocranium bone + +[Term] +id: MA:0002811 +name: temporal bone zygomatic process +xref: EMAPS:1901528 +relationship: part_of MA:0001476 ! temporal bone +relationship: part_of MA:0002810 ! zygomatic arch + +[Term] +id: MA:0002812 +name: zygomatic bone temporal process +relationship: part_of MA:0001497 ! zygomatic bone +relationship: part_of MA:0002810 ! zygomatic arch + +[Term] +id: MA:0002813 +name: oval window +synonym: "vestibular window" RELATED [] +relationship: part_of MA:0001477 ! temporal bone petrous part + +[Term] +id: MA:0002814 +name: round window +synonym: "cochlear window" RELATED [] +relationship: part_of MA:0001477 ! temporal bone petrous part + +[Term] +id: MA:0002815 +name: mandible ramus +xref: EMAPS:2510028 +relationship: part_of MA:0001487 ! mandible + +[Term] +id: MA:0002816 +name: mandible condylar process +synonym: "mandibular condyloid process" RELATED [] +relationship: part_of MA:0002815 ! mandible ramus + +[Term] +id: MA:0002817 +name: mandible head +relationship: part_of MA:0002816 ! mandible condylar process + +[Term] +id: MA:0002818 +name: mandible neck +relationship: part_of MA:0002816 ! mandible condylar process + +[Term] +id: MA:0002819 +name: mandible coronoid process +synonym: "mandibular coronoid process" RELATED [] +relationship: part_of MA:0002815 ! mandible ramus + +[Term] +id: MA:0002820 +name: mandible temporal crest +relationship: part_of MA:0002815 ! mandible ramus + +[Term] +id: MA:0002821 +name: trochanter +relationship: part_of MA:0001359 ! femur + +[Term] +id: MA:0002822 +name: greater trochanter +is_a: MA:0002821 ! trochanter + +[Term] +id: MA:0002823 +name: lesser trochanter +is_a: MA:0002821 ! trochanter + +[Term] +id: MA:0002824 +name: spiral modiolar artery +is_a: MA:0000064 ! artery + +[Term] +id: MA:0002825 +name: epididymis epithelium +xref: EMAPS:3044528 +relationship: part_of MA:0000397 ! epididymis + +[Term] +id: MA:0002826 +name: iris epithelium +synonym: "iris pigmented epithelium" RELATED [] +xref: EMAPS:3544728 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000273 ! iris + +[Term] +id: MA:0002827 +name: abdominal lymph node +xref: EMAPS:3599228 +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002828 +name: celiac lymph node +is_a: MA:0002827 ! abdominal lymph node + +[Term] +id: MA:0002829 +name: mesenteric lymph node +alt_id: MA:0002880 +xref: EMAPS:3556128 +is_a: MA:0002827 ! abdominal lymph node + +[Term] +id: MA:0002830 +name: anterior fontanel +xref: EMAPS:1919928 +is_a: MA:0001465 ! fontanel + +[Term] +id: MA:0002831 +name: trabecula carnea +alt_id: MA:0002832 +synonym: "ventricle trabecula carnea" EXACT [] +synonym: "ventricular trabecula" RELATED [] +xref: EMAPS:1862628 +relationship: part_of MA:0001879 ! heart ventricle muscular part + +[Term] +id: MA:0002833 +name: trabecula carnea cardiac muscle tissue +relationship: part_of MA:0002831 ! trabecula carnea + +[Term] +id: MA:0002834 +name: corpus luteum +xref: EMAPS:2988628 +relationship: part_of MA:0000012 ! endocrine system +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0002835 +name: sulcus ampullaris +relationship: part_of MA:0002770 ! semicircular duct ampulla + +[Term] +id: MA:0002836 +name: endochondral bone +xref: EMAPS:3530428 +is_a: MA:0002780 ! bone tissue + +[Term] +id: MA:0002837 +name: intramembranous bone +is_a: MA:0002780 ! bone tissue + +[Term] +id: MA:0002838 +name: periosteum +xref: EMAPS:3568128 +relationship: part_of MA:0001459 ! bone + +[Term] +id: MA:0002839 +name: long bone epiphyseal plate +synonym: "epiphyseal plate" RELATED [] +synonym: "growth plate" RELATED [] +xref: EMAPS:3550528 +relationship: part_of MA:0002802 ! long bone + +[Term] +id: MA:0002840 +name: basicranium +synonym: "cranial base" RELATED [] +relationship: part_of MA:0000316 ! cranium + +[Term] +id: MA:0002841 +name: otolith organ +relationship: part_of MA:0000245 ! vestibular labyrinth + +[Term] +id: MA:0002842 +name: otolithic membrane +relationship: part_of MA:0000245 ! vestibular labyrinth + +[Term] +id: MA:0002843 +name: submandibular lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002844 +name: labium majorum +synonym: "labium majus" RELATED [] +is_a: MA:0002464 ! labium + +[Term] +id: MA:0002845 +name: labium minorum +synonym: "labium minus" RELATED [] +is_a: MA:0002464 ! labium + +[Term] +id: MA:0002846 +name: kidney epithelium +xref: EMAPS:3545728 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0002847 +name: kidney glomerular epithelium +xref: EMAPS:3545828 +is_a: MA:0002846 ! kidney epithelium + +[Term] +id: MA:0002848 +name: tail tip +synonym: "end of tail" RELATED [] +relationship: part_of MA:0000008 ! tail + +[Term] +id: MA:0002849 +name: hypertrophic cartilage zone +xref: EMAPS:3541528 +relationship: part_of MA:0002836 ! endochondral bone + +[Term] +id: MA:0002850 +name: somatic nervous system +relationship: part_of MA:0000218 ! peripheral nervous system + +[Term] +id: MA:0002851 +name: lymph node B cell domain +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0002852 +name: lymph node T cell domain +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0002853 +name: elastic tissue +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0002854 +name: blood vessel layer +relationship: part_of MA:0000060 ! blood vessel + +[Term] +id: MA:0002855 +name: tunica media +is_a: MA:0002854 ! blood vessel layer + +[Term] +id: MA:0002856 +name: blood vessel elastic tissue +is_a: MA:0002857 ! cardiovascular system elastic tissue +relationship: part_of MA:0000060 ! blood vessel + +[Term] +id: MA:0002857 +name: cardiovascular system elastic tissue +is_a: MA:0002853 ! elastic tissue +relationship: part_of MA:0000010 ! cardiovascular system + +[Term] +id: MA:0002858 +name: heart elastic tissue +is_a: MA:0002857 ! cardiovascular system elastic tissue +relationship: part_of MA:0000072 ! heart + +[Term] +id: MA:0002859 +name: aorta elastic tissue +is_a: MA:0002856 ! blood vessel elastic tissue +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0002860 +name: lung elastic tissue +is_a: MA:0001820 ! respiratory system elastic tissue +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0002861 +name: tunica intima +is_a: MA:0002854 ! blood vessel layer + +[Term] +id: MA:0002862 +name: external elastic membrane +is_a: MA:0002856 ! blood vessel elastic tissue +relationship: part_of MA:0002855 ! tunica media + +[Term] +id: MA:0002863 +name: internal elastic membrane +is_a: MA:0002856 ! blood vessel elastic tissue +relationship: part_of MA:0002861 ! tunica intima + +[Term] +id: MA:0002864 +name: dentate gyrus polymorphic layer +xref: EMAPS:3528028 +is_a: MA:0002429 ! dentate gyrus layer + +[Term] +id: MA:0002865 +name: myocardium compact layer +is_a: MA:0000080 ! myocardium layer + +[Term] +id: MA:0002866 +name: myocardium trabecular layer +is_a: MA:0000080 ! myocardium layer + +[Term] +id: MA:0002867 +name: urethral opening +relationship: part_of MA:0002636 ! lower urinary tract + +[Term] +id: MA:0002868 +name: skeletal muscle connective tissue +synonym: "skeletal muscle interstitial tissue" RELATED [] +synonym: "skeletal muscle interstitum" RELATED [] +relationship: part_of MA:0003148 ! skeletal muscle + +[Term] +id: MA:0002869 +name: presacral vertebra +is_a: MA:0000309 ! vertebra + +[Term] +id: MA:0002870 +name: crista ampullaris neuroepithelium +synonym: "ampullary crest neuroepithelium" RELATED [] +relationship: part_of MA:0002771 ! crista ampullaris + +[Term] +id: MA:0002871 +name: cervical vertebra 1 ventral tubercle +synonym: "atlas ventral tubercle" RELATED [] +relationship: part_of MA:0001421 ! cervical vertebra 1 + +[Term] +id: MA:0002872 +name: cervical vertebra 2 odontoid process +synonym: "axis odontoid process" RELATED [] +xref: EMAPS:2653528 +relationship: part_of MA:0001422 ! cervical vertebra 2 + +[Term] +id: MA:0002873 +name: mandible angular process +synonym: "mandibular angle" RELATED [] +relationship: part_of MA:0001487 ! mandible + +[Term] +id: MA:0002874 +name: nasal bridge +relationship: part_of MA:0001910 ! snout + +[Term] +id: MA:0002875 +name: periorbital area +relationship: part_of MA:0002473 ! face + +[Term] +id: MA:0002876 +name: vertebra lamina +synonym: "vertebral lamina" RELATED [] +relationship: part_of MA:0001453 ! vertebra arch + +[Term] +id: MA:0002877 +name: mediastinal lymph node +xref: EMAPS:3555528 +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002878 +name: brachial lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002879 +name: lumbar lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002881 +name: pancreatic lymph node +synonym: "pyloric lymph node" RELATED [] +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002882 +name: renal lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002883 +name: sacral lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002884 +name: sciatic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0002885 +name: deep cervical lymph node +is_a: MA:0000736 ! cervical lymph node + +[Term] +id: MA:0002886 +name: superficial cervical lymph node +is_a: MA:0000736 ! cervical lymph node + +[Term] +id: MA:0002887 +name: set of connective tissues +is_a: MA:0000003 ! organ system + +[Term] +id: MA:0002888 +name: muscular system +synonym: "set of muscles" RELATED [] +xref: EMAPS:3557828 +relationship: part_of MA:0002418 ! musculoskeletal system + +[Term] +id: MA:0002889 +name: limb segment +relationship: part_of MA:0000007 ! limb + +[Term] +id: MA:0002890 +name: septal organ of Masera +xref: EMAPS:3576628 +is_a: MA:0001327 ! septal olfactory organ + +[Term] +id: MA:0002891 +name: septal organ of Gruneberg +synonym: "Gruneberg ganglion" RELATED [] +xref: EMAPS:3576528 +is_a: MA:0001327 ! septal olfactory organ + +[Term] +id: MA:0002892 +name: vestibular epithelium +xref: EMAPS:3592128 +relationship: part_of MA:0000245 ! vestibular labyrinth + +[Term] +id: MA:0002893 +name: amniotic fluid +is_a: MA:0002450 ! body fluid or substance + +[Term] +id: MA:0002894 +name: ventral posterior lateral thalamic nucleus +xref: EMAPS:3591028 +relationship: part_of MA:0000867 ! ventral posterior thalamic group + +[Term] +id: MA:0002895 +name: periaqueductal grey +xref: EMAPS:3278128 +is_a: MA:0000810 ! brain grey matter + +[Term] +id: MA:0002896 +name: external capsule +xref: EMAPS:3533128 +is_a: MA:0000945 ! cerebral white matter + +[Term] +id: MA:0002897 +name: mammary gland connective tissue +xref: EMAPS:3553728 +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0002898 +name: cribriform plate +xref: EMAPS:1920128 +relationship: part_of MA:0001483 ! ethmoid bone + +[Term] +id: MA:0002899 +name: temporomandibular joint +synonym: "tempero-mandibular joint" RELATED [] +xref: EMAPS:1919628 +is_a: MA:0000322 ! synovial joint + +[Term] +id: MA:0002900 +name: zymbal gland +synonym: "zymbal's gland" RELATED [] +is_a: MA:0003043 ! modified sebaceous gland + +[Term] +id: MA:0002901 +name: aorta wall +xref: EMAPS:3513928 +relationship: part_of MA:0000062 ! aorta + +[Term] +id: MA:0002902 +name: aorta tunica adventitia +xref: EMAPS:3513628 +relationship: part_of MA:0002901 ! aorta wall + +[Term] +id: MA:0002903 +name: aorta tunica media +xref: EMAPS:3513828 +relationship: part_of MA:0002901 ! aorta wall + +[Term] +id: MA:0002904 +name: aorta tunica intima +xref: EMAPS:3513728 +relationship: part_of MA:0002901 ! aorta wall + +[Term] +id: MA:0002905 +name: decidua basalis +xref: EMAPS:3527028 +relationship: part_of MA:0001722 ! decidua + +[Term] +id: MA:0002906 +name: decidua capsularis +xref: EMAPS:3527128 +relationship: part_of MA:0001722 ! decidua + +[Term] +id: MA:0002907 +name: ovary primary follicle +xref: EMAPS:3563128 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0002908 +name: ovary secondary follicle +xref: EMAPS:3563228 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0002909 +name: ovary antral follicle +synonym: "Graafian follicle" RELATED [] +xref: EMAPS:3076328 +xref: EMAPS:3077728 +xref: EMAPS:3562528 +is_a: MA:0001707 ! ovary follicle + +[Term] +id: MA:0002910 +name: vibrissa follicle +xref: EMAPS:2672028 +relationship: part_of MA:0000163 ! vibrissa + +[Term] +id: MA:0002911 +name: mammary gland fat +xref: EMAPS:3553928 +is_a: MA:0000009 ! adipose tissue +relationship: part_of MA:0000145 ! mammary gland + +[Term] +id: MA:0002912 +name: prostate gland stroma +xref: EMAPS:3571428 +relationship: part_of MA:0000404 ! prostate gland + +[Term] +id: MA:0002913 +name: seminal vesicle muscle layer +xref: EMAPS:2977328 +relationship: part_of MA:0000410 ! seminal vesicle + +[Term] +id: MA:0002914 +name: distal phalanx +xref: EMAPS:3528728 +is_a: MA:0000304 ! phalanx + +[Term] +id: MA:0002915 +name: middle phalanx +xref: EMAPS:3557228 +is_a: MA:0000304 ! phalanx + +[Term] +id: MA:0002916 +name: proximal phalanx +xref: EMAPS:3571628 +is_a: MA:0000304 ! phalanx + +[Term] +id: MA:0002917 +name: amygdalahippocampal area +xref: EMAPS:3512428 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002918 +name: amygdaloppiriform transition area +xref: EMAPS:3512528 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002919 +name: anterior amygdaloid area +xref: EMAPS:3512728 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002920 +name: anterior cortical amydaloid nucleus +xref: EMAPS:3512828 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002921 +name: basolateral amygdaloid nucleus +xref: EMAPS:3516728 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002922 +name: basomedial amygdaloid nucleus +xref: EMAPS:3516828 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002923 +name: central amygdaloid nucleus +xref: EMAPS:3520428 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002924 +name: cortical amygdaloid nucleus +xref: EMAPS:3525428 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002925 +name: intercalated amygdaloid nucleus +xref: EMAPS:3543428 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002926 +name: lateral amygdaloid nucleus +xref: EMAPS:3547628 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002927 +name: medial amygdaloid nucleus +xref: EMAPS:3554328 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002928 +name: posterior amygdaloid nucleus +xref: EMAPS:3569428 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002929 +name: posterolateral cortical amygdaloid nucleus +xref: EMAPS:3569928 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002930 +name: posteromedial cortical amygdaloid nucleus +xref: EMAPS:3570028 +relationship: part_of MA:0000887 ! amygdala + +[Term] +id: MA:0002931 +name: mesometrium +xref: EMAPS:3556228 +relationship: part_of MA:0000389 ! uterus + +[Term] +id: MA:0002932 +name: accessory olfactory bulb external plexiform layer +xref: EMAPS:3510728 +relationship: part_of MA:0000966 ! accessory olfactory bulb + +[Term] +id: MA:0002933 +name: accessory olfactory bulb granule cell layer +xref: EMAPS:3510928 +relationship: part_of MA:0000966 ! accessory olfactory bulb + +[Term] +id: MA:0002934 +name: accessory olfactory bulb internal plexiform layer +xref: EMAPS:3511028 +relationship: part_of MA:0000966 ! accessory olfactory bulb + +[Term] +id: MA:0002935 +name: kidney medulla collecting duct +xref: EMAPS:3545928 +is_a: MA:0000371 ! kidney collecting duct +relationship: part_of MA:0000373 ! kidney medulla + +[Term] +id: MA:0002936 +name: bartholin's gland +synonym: "greater vestibular gland" RELATED [] +synonym: "major vestibular gland" RELATED [] +is_a: MA:0000383 ! female reproductive gland + +[Term] +id: MA:0002937 +name: trachea gland +relationship: part_of MA:0001860 ! trachea submucosa + +[Term] +id: MA:0002938 +name: lingual gland duct +is_a: MA:0001586 ! salivary duct + +[Term] +id: MA:0002939 +name: interventricular septum membranous part +synonym: "membranous interventricular septum" RELATED [] +xref: EMAPS:1824628 +relationship: part_of MA:0000085 ! heart interventricular septum + +[Term] +id: MA:0002940 +name: interventricular septum muscular part +synonym: "muscular interventricular septum" RELATED [] +xref: EMAPS:1824728 +relationship: part_of MA:0000085 ! heart interventricular septum + +[Term] +id: MA:0002941 +name: subcommissural organ +xref: EMAPS:3582828 +is_a: MA:0002943 ! secretory circumventricular organ +relationship: part_of MA:0000211 ! tectum + +[Term] +id: MA:0002942 +name: circumventricular organ +xref: EMAPS:3524328 +relationship: part_of MA:0000168 ! brain + +[Term] +id: MA:0002943 +name: secretory circumventricular organ +xref: EMAPS:3575928 +is_a: MA:0000720 ! neuroendocrine gland +is_a: MA:0002942 ! circumventricular organ + +[Term] +id: MA:0002944 +name: sensory circumventricular organ +is_a: MA:0002942 ! circumventricular organ + +[Term] +id: MA:0002945 +name: 4th ventricle aperture +relationship: part_of MA:0000196 ! 4th ventricle + +[Term] +id: MA:0002946 +name: 4th ventricle lateral aperture +synonym: "foramen of Key-Retzius" RELATED [] +synonym: "foramen of Retzius" RELATED [] +synonym: "forament of Luschka" RELATED [] +is_a: MA:0002945 ! 4th ventricle aperture + +[Term] +id: MA:0002947 +name: 4th ventricle median aperture +synonym: "arachnoid foramen" RELATED [] +synonym: "foramen of Magendie" RELATED [] +is_a: MA:0002945 ! 4th ventricle aperture + +[Term] +id: MA:0002948 +name: pelvis ligament +synonym: "pelvic ligament" RELATED [] +is_a: MA:0000533 ! pelvis connective tissue + +[Term] +id: MA:0002949 +name: left eye +is_a: MA:0000261 ! eye + +[Term] +id: MA:0002950 +name: right eye +is_a: MA:0000261 ! eye + +[Term] +id: MA:0002951 +name: gastroesophageal sphincter +synonym: "cardiac sphincter" RELATED [] +synonym: "lower esophageal sphincter" RELATED [] +relationship: part_of MA:0001609 ! stomach cardiac region + +[Term] +id: MA:0002952 +name: pyloric sphincter +relationship: part_of MA:0002560 ! stomach pyloric region + +[Term] +id: MA:0002953 +name: parametrial fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0002954 +name: cervical vertebra 1 arcus anterior +synonym: "anterior arch of atlas" RELATED [] +synonym: "arcus anterior atlantis" RELATED [] +relationship: part_of MA:0001421 ! cervical vertebra 1 + +[Term] +id: MA:0002955 +name: atrium auricular region +relationship: part_of MA:0000073 ! heart atrium + +[Term] +id: MA:0002956 +name: omental fat pad +is_a: MA:0000472 ! abdominal fat pad + +[Term] +id: MA:0002957 +name: stylohyoid ligament +synonym: "stylo-hyoid ligament" RELATED [] +is_a: MA:0003005 ! skeletal ligament + +[Term] +id: MA:0002958 +name: hyoid bone body +synonym: "base of hyoid bone" RELATED [] +synonym: "basihyal bone" RELATED [] +synonym: "basihyoid bone" RELATED [] +synonym: "body of hyoid bone" RELATED [] +synonym: "hyoid bone base" RELATED [] +xref: EMAPS:1865328 +relationship: part_of MA:0001484 ! hyoid bone + +[Term] +id: MA:0002959 +name: hyoid bone greater horn +synonym: "hyoid bone greater cornu" RELATED [] +synonym: "hyoid bone superior horn" RELATED [] +synonym: "hyoid bone upper horn" RELATED [] +xref: EMAPS:1865128 +relationship: part_of MA:0001484 ! hyoid bone + +[Term] +id: MA:0002960 +name: hyoid bone lesser horn +synonym: "hyoid bone lesser cornu" RELATED [] +synonym: "hyoid bone lower horn" RELATED [] +xref: EMAPS:1865228 +relationship: part_of MA:0001484 ! hyoid bone + +[Term] +id: MA:0002961 +name: lymphatic system +xref: EMAPS:1824828 +relationship: part_of MA:0002435 ! lymphoid system +relationship: part_of MA:0002718 ! vascular system + +[Term] +id: MA:0002962 +name: hemolymphoid system gland +xref: EMAPS:1876628 +relationship: part_of MA:0000013 ! hemolymphoid system + +[Term] +id: MA:0002963 +name: cerebellum lobe +xref: EMAPS:3522028 +relationship: part_of MA:0000199 ! cerebellar cortex + +[Term] +id: MA:0002964 +name: cerebellum posterior lobe +xref: EMAPS:3522228 +is_a: MA:0002963 ! cerebellum lobe + +[Term] +id: MA:0002965 +name: cerebellum flocculonodular lobe +is_a: MA:0002963 ! cerebellum lobe + +[Term] +id: MA:0002966 +name: cerebellum lobule +relationship: part_of MA:0000199 ! cerebellar cortex + +[Term] +id: MA:0002967 +name: cerebellum hemisphere lobule +is_a: MA:0002966 ! cerebellum lobule +relationship: part_of MA:0000200 ! cerebellum hemisphere + +[Term] +id: MA:0002968 +name: cerebellum vermis lobule +xref: EMAPS:3522428 +is_a: MA:0002966 ! cerebellum lobule +relationship: part_of MA:0000202 ! cerebellum vermis + +[Term] +id: MA:0002969 +name: anterior cerebellum vermis +relationship: part_of MA:0000202 ! cerebellum vermis +relationship: part_of MA:0000991 ! cerebellum anterior lobe + +[Term] +id: MA:0002970 +name: posterior cerebellum vermis +relationship: part_of MA:0000202 ! cerebellum vermis +relationship: part_of MA:0002964 ! cerebellum posterior lobe + +[Term] +id: MA:0002971 +name: dorsal striatum +relationship: part_of MA:0000891 ! striatum + +[Term] +id: MA:0002972 +name: ventral striatum +relationship: part_of MA:0000891 ! striatum + +[Term] +id: MA:0002973 +name: frontonasal suture +xref: EMAPS:3535928 +is_a: MA:0001475 ! cranial suture + +[Term] +id: MA:0002974 +name: pararenal fat +synonym: "paranephric fat" RELATED [] +synonym: "pararenal fascia" RELATED [] +synonym: "pararenal fat body" RELATED [] +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0002975 +name: perirenal fat +synonym: "adipose capsule of kidney" RELATED [] +synonym: "fatty capsule of kidney" RELATED [] +synonym: "perinephric fat" RELATED [] +synonym: "periphrenic fascia" RELATED [] +synonym: "perirenal fascia" RELATED [] +synonym: "perirenal fat capsule" RELATED [] +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0002976 +name: long bone epiphyseal plate proliferative zone +synonym: "zone of proliferation" RELATED [] +xref: EMAPS:3550728 +relationship: part_of MA:0002839 ! long bone epiphyseal plate + +[Term] +id: MA:0002977 +name: long bone epiphyseal plate hypertrophic zone +synonym: "maturation zone" RELATED [] +synonym: "zone of hypertrophic chondrocytes" RELATED [] +xref: EMAPS:3550628 +is_a: MA:0002849 ! hypertrophic cartilage zone +relationship: part_of MA:0002839 ! long bone epiphyseal plate + +[Term] +id: MA:0002978 +name: septal nucleus +xref: EMAPS:3576328 +relationship: part_of MA:0000924 ! septum of telencephalon + +[Term] +id: MA:0002979 +name: septum pellucidum +synonym: "septum lucidum" RELATED [] +relationship: part_of MA:0000924 ! septum of telencephalon + +[Term] +id: MA:0002980 +name: dorsal raphe nucleus +xref: EMAPS:3529328 +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000212 ! tegmentum + +[Term] +id: MA:0002981 +name: raphe obscurus nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0002982 +name: sublingual ganglion +is_a: MA:0002469 ! parasympathetic ganglion + +[Term] +id: MA:0002983 +name: left ventricle myocardium +xref: EMAPS:1733928 +is_a: MA:0000082 ! ventricle myocardium +relationship: part_of MA:0000092 ! heart left ventricle + +[Term] +id: MA:0002984 +name: right ventricle myocardium +xref: EMAPS:1734228 +is_a: MA:0000082 ! ventricle myocardium +relationship: part_of MA:0000093 ! heart right ventricle + +[Term] +id: MA:0002985 +name: manubrium mallei +synonym: "handle of malleus" RELATED [] +synonym: "malleal manubrium" RELATED [] +synonym: "malleus handle" RELATED [] +synonym: "malleus manubrium" RELATED [] +synonym: "manubrium of malleus" RELATED [] +relationship: part_of MA:0001216 ! malleus + +[Term] +id: MA:0002986 +name: post-cranial axial skeleton +relationship: part_of MA:0000308 ! axial skeleton + +[Term] +id: MA:0002987 +name: malleus head +relationship: part_of MA:0001216 ! malleus + +[Term] +id: MA:0002988 +name: malleus neck +relationship: part_of MA:0001216 ! malleus + +[Term] +id: MA:0002989 +name: lymph node germinal center +xref: EMAPS:3552828 +relationship: part_of MA:0000744 ! lymph node secondary follicle + +[Term] +id: MA:0002990 +name: lymph node follicular mantle +relationship: part_of MA:0000744 ! lymph node secondary follicle + +[Term] +id: MA:0002991 +name: ovary stroma +xref: EMAPS:3563428 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0002992 +name: thalamic nucleus +xref: EMAPS:3585928 +relationship: part_of MA:0000179 ! thalamus + +[Term] +id: MA:0002993 +name: tendo calcaneus +synonym: "Achilles tendon" RELATED [] +xref: EMAPS:3585328 +is_a: MA:0000115 ! tendon + +[Term] +id: MA:0002994 +name: malleus process brevis +relationship: part_of MA:0001216 ! malleus + +[Term] +id: MA:0002995 +name: kidney medulla tubule +synonym: "medullary tubule" RELATED [] +xref: EMAPS:3555728 +is_a: MA:0000377 ! kidney tubule +relationship: part_of MA:0000373 ! kidney medulla + +[Term] +id: MA:0002996 +name: nephrogenic zone +xref: EMAPS:2772128 +relationship: part_of MA:0000368 ! kidney + +[Term] +id: MA:0002997 +name: cap mesenchyme +xref: EMAPS:2773528 +relationship: part_of MA:0002996 ! nephrogenic zone + +[Term] +id: MA:0002998 +name: nephrogenic interstitium +xref: EMAPS:1795328 +relationship: part_of MA:0002996 ! nephrogenic zone + +[Term] +id: MA:0002999 +name: pretubular aggregate +xref: EMAPS:2774228 +relationship: part_of MA:0002996 ! nephrogenic zone + +[Term] +id: MA:0003000 +name: anatomical structure +is_a: MA:0000001 ! mouse anatomical entity + +[Term] +id: MA:0003001 +name: organ +xref: EMAPS:3594928 +is_a: MA:0003000 ! anatomical structure +relationship: part_of MA:0002405 ! postnatal mouse + +[Term] +id: MA:0003002 +name: tissue +xref: EMAPS:3586828 +is_a: MA:0003000 ! anatomical structure +relationship: part_of MA:0002405 ! postnatal mouse + +[Term] +id: MA:0003003 +name: spiral prominence +xref: EMAPS:3579928 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0003004 +name: nonskeletal ligament +is_a: MA:0000113 ! ligament + +[Term] +id: MA:0003005 +name: skeletal ligament +is_a: MA:0000113 ! ligament + +[Term] +id: MA:0003006 +name: skeleton +xref: EMAPS:1721328 +relationship: part_of MA:0000018 ! skeletal system + +[Term] +id: MA:0003007 +name: articular system +xref: EMAPS:3515028 +relationship: part_of MA:0000018 ! skeletal system + +[Term] +id: MA:0003008 +name: perichondrium +xref: EMAPS:3567628 +is_a: MA:0000011 ! connective tissue + +[Term] +id: MA:0003009 +name: baroreceptor +relationship: part_of MA:0000060 ! blood vessel + +[Term] +id: MA:0003010 +name: footpad +relationship: part_of MA:0002714 ! autopod + +[Term] +id: MA:0003011 +name: digit skin +xref: EMAPS:3261528 +relationship: part_of MA:0000690 ! limb digit + +[Term] +id: MA:0003012 +name: interdigital region +xref: EMAPS:3261828 +is_a: MA:0002714 ! autopod + +[Term] +id: MA:0003013 +name: rete testis +xref: EMAPS:1833228 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0003014 +name: limiting ridge of stomach +synonym: "" RELATED [] +synonym: "margo plicatus" RELATED [] +is_a: MA:0002561 ! stomach region +relationship: part_of MA:0000353 ! stomach + +[Term] +id: MA:0003015 +name: hepatic vein +xref: EMAPS:1922128 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0003016 +name: hair follicle infundibulum +relationship: part_of MA:0000154 ! hair follicle + +[Term] +id: MA:0003017 +name: apex of heart ventricle +synonym: "apex of cardiac ventricle" RELATED [] +relationship: part_of MA:0000091 ! heart ventricle + +[Term] +id: MA:0003018 +name: supraoptic crest +synonym: "vascular organ of lamina terminalis" RELATED [] +is_a: MA:0002944 ! sensory circumventricular organ + +[Term] +id: MA:0003019 +name: inferior olivary commissure +synonym: "interolivary commissure" RELATED [] +is_a: MA:0002741 ! brainstem white matter +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0003020 +name: ureterovesical junction +synonym: "vesico-ureteral junction" RELATED [] +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0003021 +name: ureteropelvic junction +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0003022 +name: retrotrapezoid nucleus +is_a: MA:0000821 ! brainstem nucleus +relationship: part_of MA:0000206 ! medulla oblongata + +[Term] +id: MA:0003023 +name: limb digit 1 +is_a: MA:0000690 ! limb digit + +[Term] +id: MA:0003024 +name: oblique abdominal muscle +xref: EMAPS:3560328 +is_a: MA:0000520 ! abdomen muscle +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0003025 +name: serratus muscle +xref: EMAPS:3576928 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0003026 +name: platysma +xref: EMAPS:1819028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0003027 +name: lymph node subcortical sinus +relationship: part_of MA:0000139 ! lymph node + +[Term] +id: MA:0003028 +name: subcutaneous lymph node +is_a: MA:0000139 ! lymph node +relationship: part_of MA:0000151 ! skin + +[Term] +id: MA:0003029 +name: pancreatic fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0003030 +name: nasal associated lymphoid tissue +is_a: MA:0000140 ! mucosa associated lymphoid tissue + +[Term] +id: MA:0003031 +name: base of tongue +relationship: part_of MA:0000347 ! tongue + +[Term] +id: MA:0003032 +name: left hepatic vein +is_a: MA:0003015 ! hepatic vein + +[Term] +id: MA:0003033 +name: middle hepatic vein +is_a: MA:0003015 ! hepatic vein + +[Term] +id: MA:0003034 +name: right hepatic vein +is_a: MA:0003015 ! hepatic vein + +[Term] +id: MA:0003035 +name: accessory hepatic vein +is_a: MA:0003015 ! hepatic vein + +[Term] +id: MA:0003036 +name: ovarian bursa +relationship: part_of MA:0000449 ! peritoneum + +[Term] +id: MA:0003037 +name: hyoid apparatus +is_a: MA:0000569 ! head or neck bone + +[Term] +id: MA:0003038 +name: gland +xref: EMAPS:1842528 +is_a: MA:0003001 ! organ + +[Term] +id: MA:0003039 +name: eccrine sweat gland +is_a: MA:0003041 ! merocrine gland + +[Term] +id: MA:0003040 +name: apocrine gland +xref: EMAPS:3514128 +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0003041 +name: merocrine gland +synonym: "eccrine gland" RELATED [] +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0003042 +name: holocrine gland +is_a: MA:0002564 ! exocrine gland + +[Term] +id: MA:0003043 +name: modified sebaceous gland +is_a: MA:0002565 ! sebaceous gland + +[Term] +id: MA:0003044 +name: clitoral/preputial gland +is_a: MA:0003043 ! modified sebaceous gland + +[Term] +id: MA:0003045 +name: cauda equina +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0003046 +name: perianal skin +relationship: part_of MA:0000546 ! pelvis skin + +[Term] +id: MA:0003047 +name: skeletal tissue +is_a: MA:0003002 ! tissue + +[Term] +id: MA:0003048 +name: posterior abdominal aorta +relationship: part_of MA:0000474 ! abdominal aorta + +[Term] +id: MA:0003049 +name: tibia diaphysis +is_a: MA:0002803 ! long bone diaphysis +relationship: part_of MA:0001361 ! tibia + +[Term] +id: MA:0003050 +name: femur head +relationship: part_of MA:0001359 ! femur + +[Term] +id: MA:0003051 +name: aortic sinus +relationship: part_of MA:0002570 ! ascending aorta + +[Term] +id: MA:0003052 +name: femur metaphysis +is_a: MA:0001363 ! long bone metaphysis +relationship: part_of MA:0001359 ! femur + +[Term] +id: MA:0003053 +name: iliac crest +relationship: part_of MA:0001336 ! ilium + +[Term] +id: MA:0003054 +name: auricular vein +is_a: MA:0000067 ! vein + +[Term] +id: MA:0003055 +name: femur diaphysis +is_a: MA:0002803 ! long bone diaphysis +relationship: part_of MA:0001359 ! femur + +[Term] +id: MA:0003056 +name: femur epiphysis +is_a: MA:0001362 ! long bone epiphysis +relationship: part_of MA:0001359 ! femur + +[Term] +id: MA:0003057 +name: abdominal cavity +is_a: MA:0002447 ! body cavity +relationship: part_of MA:0000021 ! abdominal segment of trunk + +[Term] +id: MA:0003058 +name: anal sac +relationship: part_of MA:0000329 ! anal region + +[Term] +id: MA:0003059 +name: buccal pouch +relationship: part_of MA:0002474 ! mouth + +[Term] +id: MA:0003060 +name: epithelium +xref: EMAPS:3273828 +is_a: MA:0003002 ! tissue + +[Term] +id: MA:0003061 +name: cranial cavity +is_a: MA:0002447 ! body cavity +relationship: part_of MA:0000023 ! head + +[Term] +id: MA:0003062 +name: interscapular brown adipose tissue +synonym: "IBAT" RELATED [] +is_a: MA:0000057 ! brown adipose tissue + +[Term] +id: MA:0003063 +name: mediastinal fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0003064 +name: periovarian fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0003065 +name: ileocecocolic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003066 +name: iliac lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003067 +name: mandibular lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003068 +name: tracheobronchial lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003069 +name: prescapular lymph node +is_a: MA:0000736 ! cervical lymph node + +[Term] +id: MA:0003070 +name: retropharyngeal lymph node +is_a: MA:0000736 ! cervical lymph node + +[Term] +id: MA:0003071 +name: gastric lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003072 +name: hepatic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003073 +name: paraaortic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003074 +name: splenic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003075 +name: mediastinum +relationship: part_of MA:0000022 ! thoracic segment of trunk + +[Term] +id: MA:0003076 +name: mediastinum connective tissue +is_a: MA:0003075 ! mediastinum + +[Term] +id: MA:0003077 +name: mesenteric adipose tissue +is_a: MA:0000009 ! adipose tissue + +[Term] +id: MA:0003078 +name: bronchial lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003079 +name: snout skin +relationship: part_of MA:0000582 ! head skin +relationship: part_of MA:0001910 ! snout + +[Term] +id: MA:0003080 +name: spinal cord segment +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0003081 +name: spinal cord cervical segment +is_a: MA:0003080 ! spinal cord segment + +[Term] +id: MA:0003082 +name: spinal cord thoracic segment +is_a: MA:0003080 ! spinal cord segment + +[Term] +id: MA:0003083 +name: spinal cord lumbar segment> +is_a: MA:0003080 ! spinal cord segment + +[Term] +id: MA:0003084 +name: spinal cord coccygeal segment +is_a: MA:0003080 ! spinal cord segment + +[Term] +id: MA:0003085 +name: spinal cord sacral segment +is_a: MA:0003080 ! spinal cord segment + +[Term] +id: MA:0003086 +name: eye trabecular meshwork +relationship: part_of MA:0002484 ! eye anterior segment + +[Term] +id: MA:0003087 +name: axilla skin +is_a: MA:0000596 ! arm skin + +[Term] +id: MA:0003088 +name: parotid lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003089 +name: pelvic cavity +is_a: MA:0002447 ! body cavity +relationship: part_of MA:0000030 ! pelvis + +[Term] +id: MA:0003090 +name: nose skin +relationship: part_of MA:0003079 ! snout skin + +[Term] +id: MA:0003091 +name: axillary fat pad +is_a: MA:0002481 ! fat pad + +[Term] +id: MA:0003092 +name: auricular lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003093 +name: scrotum skin +relationship: part_of MA:0000409 ! scrotum + +[Term] +id: MA:0003094 +name: common hepatic artery +is_a: MA:0001963 ! hepatic artery + +[Term] +id: MA:0003095 +name: proper hepatic artery +is_a: MA:0001963 ! hepatic artery + +[Term] +id: MA:0003096 +name: left hepatic artery +is_a: MA:0001963 ! hepatic artery + +[Term] +id: MA:0003097 +name: right hepatic artery +is_a: MA:0001963 ! hepatic artery + +[Term] +id: MA:0003098 +name: lung lobe +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0003099 +name: lung hilus +synonym: "lung hilum" RELATED [] +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0003100 +name: paravertebral ganglion +is_a: MA:0000226 ! sympathetic ganglion + +[Term] +id: MA:0003101 +name: prevertebral ganglion +synonym: "collateral ganglion" RELATED [] +synonym: "previsceral ganglion" RELATED [] +is_a: MA:0000226 ! sympathetic ganglion + +[Term] +id: MA:0003102 +name: superior mesenteric ganglion +is_a: MA:0003101 ! prevertebral ganglion + +[Term] +id: MA:0003103 +name: inferior mesenteric ganglion +is_a: MA:0003101 ! prevertebral ganglion + +[Term] +id: MA:0003104 +name: heel skin +relationship: part_of MA:0000654 ! foot skin + +[Term] +id: MA:0003105 +name: foot pad skin +relationship: part_of MA:0000654 ! foot skin +relationship: part_of MA:0003010 ! footpad + +[Term] +id: MA:0003106 +name: tibia metaphysis +is_a: MA:0001363 ! long bone metaphysis +relationship: part_of MA:0001361 ! tibia + +[Term] +id: MA:0003107 +name: duodenal papilla +xref: EMAPS:1866228 +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003108 +name: choledochoduodenal junction +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003109 +name: intraorbital lacrimal gland +is_a: MA:0001296 ! lacrimal gland + +[Term] +id: MA:0003110 +name: exorbital lacrimal gland +is_a: MA:0001296 ! lacrimal gland + +[Term] +id: MA:0003111 +name: sural nerve +is_a: MA:0000228 ! peripheral nerve +relationship: part_of MA:0001173 ! tibial nerve + +[Term] +id: MA:0003112 +name: tarsal joint +is_a: MA:0000464 ! foot joint +relationship: part_of MA:0000050 ! tarsus + +[Term] +id: MA:0003113 +name: tibia epiphysis +is_a: MA:0001362 ! long bone epiphysis +relationship: part_of MA:0001361 ! tibia + +[Term] +id: MA:0003114 +name: tracheal bifurcation +relationship: part_of MA:0000441 ! trachea + +[Term] +id: MA:0003115 +name: masticatory muscle +is_a: MA:0000579 ! cranial/facial muscle + +[Term] +id: MA:0003116 +name: bulbospongiosus +synonym: "bulbocavernosus" RELATED [] +is_a: MA:0001743 ! penis erectile tissue + +[Term] +id: MA:0003117 +name: entorhinal cortex +xref: EMAPS:3531328 +relationship: part_of MA:0000920 ! retrohippocampal cortex + +[Term] +id: MA:0003118 +name: thymic lymph node +is_a: MA:0000139 ! lymph node + +[Term] +id: MA:0003119 +name: alveolar process +xref: EMAPS:3511828 +relationship: part_of MA:0001905 ! jaw + +[Term] +id: MA:0003120 +name: autopod skin +synonym: "paw skin" RELATED [] +xref: EMAPS:3272328 +relationship: part_of MA:0000694 ! limb skin +relationship: part_of MA:0002714 ! autopod + +[Term] +id: MA:0003121 +name: dental follicle +synonym: "dental sac" RELATED [] +xref: EMAPS:3527528 +relationship: part_of MA:0003152 ! tooth mesenchyme + +[Term] +id: MA:0003122 +name: dentate gyrus molecular layer +xref: EMAPS:3527928 +is_a: MA:0002429 ! dentate gyrus layer + +[Term] +id: MA:0003123 +name: digit connective tissue +xref: EMAPS:3271928 +relationship: part_of MA:0000690 ! limb digit + +[Term] +id: MA:0003124 +name: prostate gland dorsal lobe +xref: EMAPS:2980828 +is_a: MA:0001738 ! prostate gland lobe +relationship: part_of MA:0001739 ! prostate gland dorsolateral lobe + +[Term] +id: MA:0003125 +name: prostate gland lateral lobe +xref: EMAPS:2982228 +is_a: MA:0001738 ! prostate gland lobe +relationship: part_of MA:0001739 ! prostate gland dorsolateral lobe + +[Term] +id: MA:0003126 +name: perpendicular plate +xref: EMAPS:2511428 +relationship: part_of MA:0001483 ! ethmoid bone + +[Term] +id: MA:0003127 +name: fasciola cinereum +xref: EMAPS:3533928 +relationship: part_of MA:0000189 ! hippocampal formation + +[Term] +id: MA:0003128 +name: greater omentum +xref: EMAPS:1866028 +relationship: part_of MA:0001618 ! dorsal mesogastrium + +[Term] +id: MA:0003129 +name: induseum griseum +xref: EMAPS:3543028 +relationship: part_of MA:0000189 ! hippocampal formation + +[Term] +id: MA:0003130 +name: jaw bone +xref: EMAPS:3545328 +relationship: part_of MA:0001905 ! jaw + +[Term] +id: MA:0003131 +name: left lung epithelium +xref: EMAPS:1765528 +is_a: MA:0001783 ! lung epithelium +relationship: part_of MA:0000425 ! left lung + +[Term] +id: MA:0003132 +name: right lung epithelium +xref: EMAPS:1766328 +is_a: MA:0001783 ! lung epithelium +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0003133 +name: left lung lobar bronchus +xref: EMAPS:1765628 +is_a: MA:0000437 ! lobar bronchus +relationship: part_of MA:0000425 ! left lung + +[Term] +id: MA:0003134 +name: right lung lobar bronchus +xref: EMAPS:1766428 +is_a: MA:0000437 ! lobar bronchus +relationship: part_of MA:0000426 ! right lung + +[Term] +id: MA:0003135 +name: left lung lobar bronchus epithelium +xref: EMAPS:1765828 +is_a: MA:0001842 ! lobar bronchus epithelium +relationship: part_of MA:0003133 ! left lung lobar bronchus + +[Term] +id: MA:0003136 +name: right lung lobar bronchus epitheium +xref: EMAPS:1766628 +is_a: MA:0001842 ! lobar bronchus epithelium +relationship: part_of MA:0003134 ! right lung lobar bronchus + +[Term] +id: MA:0003137 +name: liver blood vessel +xref: EMAPS:3549828 +relationship: part_of MA:0000358 ! liver + +[Term] +id: MA:0003138 +name: nasal septum cartilage +xref: EMAPS:2509128 +relationship: part_of MA:0000285 ! nasal septum + +[Term] +id: MA:0003139 +name: integumental system muscle +xref: EMAPS:18187228 +relationship: part_of MA:0000014 ! integumental system + +[Term] +id: MA:0003140 +name: integumental system superficial muscle +xref: EMAPS:1818828 +is_a: MA:0003139 ! integumental system muscle + +[Term] +id: MA:0003141 +name: panniculus carnosus group +xref: EMAPS:1818928 +is_a: MA:0003140 ! integumental system superficial muscle + +[Term] +id: MA:0003142 +name: auditory tube epithelium +xref: EMAPS:3280128 +relationship: part_of MA:0000255 ! auditory tube + +[Term] +id: MA:0003143 +name: pharynx mucosa +xref: EMAPS:2695728 +relationship: part_of MA:0000432 ! pharynx + +[Term] +id: MA:0003144 +name: prevertebral muscle of neck +xref: EMAPS:2513028 +is_a: MA:0003148 ! skeletal muscle + +[Term] +id: MA:0003145 +name: radio-ulnar joint +xref: EMAPS:1920628 +is_a: MA:0000460 ! wrist joint + +[Term] +id: MA:0003146 +name: proximal radio-ulnar joint +xref: EMAPS:1931728 +is_a: MA:0003145 ! radio-ulnar joint + +[Term] +id: MA:0003147 +name: raphe nucleus +xref: EMAPS:3572128 +is_a: MA:0000821 ! brainstem nucleus + +[Term] +id: MA:0003148 +name: skeletal muscle +xref: EMAPS:3598828 +is_a: MA:0000015 ! muscle organ + +[Term] +id: MA:0003149 +name: dentate gyrus subgranular zone +xref: EMAPS:3583128 +relationship: part_of MA:0000190 ! dentate gyrus + +[Term] +id: MA:0003150 +name: taenia tecta +xref: EMAPS:3584728 +is_a: MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0003151 +name: tooth epithelium +xref: EMAPS:3290328 +relationship: part_of MA:0000348 ! tooth + +[Term] +id: MA:0003152 +name: tooth mesenchyme +xref: EMAPS:3289128 +relationship: part_of MA:0000348 ! tooth + +[Term] +id: MA:0003153 +name: axial muscle +xref: EMAPS:1816728 +is_a: MA:0000165 ! set of skeletal muscles + +[Term] +id: MA:0003154 +name: axial skeleton cervical region +xref: EMAPS:1721528 +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0003155 +name: axial skeleton thoracic region +xref: EMAPS:1739628 +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0003156 +name: axial skeleton lumbar region +xref: EMAPS:1739328 +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0003157 +name: axial skeleton sacral region +xref: EMAPS:1767628 +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0003158 +name: axial skeleton tail region +xref: EMAPS:1804328 +relationship: part_of MA:0002986 ! post-cranial axial skeleton + +[Term] +id: MA:0003159 +name: facial bone +xref: EMAPS:1901928 +is_a: MA:0001482 ! viscerocranium bone + +[Term] +id: MA:0003160 +name: facial muscle +xref: EMAPS:2513328 +is_a: MA:0000579 ! cranial/facial muscle + +[Term] +id: MA:0003161 +name: ear epithelium +xref: EMAPS:3280028 +is_a: MA:0003174 ! sensory organ epithelium +relationship: part_of MA:0000236 ! ear + +[Term] +id: MA:0003162 +name: eye epithelium +xref: EMAPS:3595728 +is_a: MA:0003174 ! sensory organ epithelium +relationship: part_of MA:0000261 ! eye + +[Term] +id: MA:0003163 +name: eyelid epithelium +xref: EMAPS:3275828 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000268 ! eyelid + +[Term] +id: MA:0003164 +name: inner ear vestibular component +xref: EMAPS:1728628 +relationship: part_of MA:0000237 ! inner ear + +[Term] +id: MA:0003165 +name: intercostal muscle +xref: EMAPS:1852128 +is_a: MA:0003153 ! axial muscle + +[Term] +id: MA:0003166 +name: intercostal vein +xref: EMAPS:1876228 +is_a: MA:0000067 ! vein + +[Term] +id: MA:0003167 +name: hepatobiliary system epithelium +xref: EMAPS:3595028 +relationship: part_of MA:0000324 ! hepatobiliary system + +[Term] +id: MA:0003168 +name: lung parenchyma +xref: EMAPS:3552228 +relationship: part_of MA:0000415 ! lung + +[Term] +id: MA:0003169 +name: middle ear epithelium +xref: EMAPS:3567328 +is_a: MA:0003161 ! ear epithelium +relationship: part_of MA:0000253 ! middle ear + +[Term] +id: MA:0003170 +name: outer ear epithelium +xref: EMAPS:3595628 +is_a: MA:0003161 ! ear epithelium +relationship: part_of MA:0000258 ! outer ear + +[Term] +id: MA:0003171 +name: nose epithelium +xref: EMAPS:3595928 +is_a: MA:0003174 ! sensory organ epithelium +relationship: part_of MA:0000281 ! nose + +[Term] +id: MA:0003172 +name: naris epithelium +xref: EMAPS:3595928 +is_a: MA:0003171 ! nose epithelium +relationship: part_of MA:0000282 ! naris + +[Term] +id: MA:0003173 +name: retina epithelium +xref: EMAPS:3573828 +is_a: MA:0003162 ! eye epithelium +relationship: part_of MA:0000276 ! retina + +[Term] +id: MA:0003174 +name: sensory organ epithelium +xref: EMAPS:3595228 +relationship: part_of MA:0000017 ! sensory organ + +[Term] +id: MA:0003175 +name: sensory organ cartilage +xref: EMAPS:3597828 +relationship: part_of MA:0000017 ! sensory organ + +[Term] +id: MA:0003176 +name: spiral vessel +xref: EMAPS:3580128 +relationship: part_of MA:0000243 ! cochlear duct + +[Term] +id: MA:0003177 +name: splenic artery +xref: EMAPS:1921628 +is_a: MA:0000064 ! artery + +[Term] +id: MA:0003178 +name: tongue papilla epithelium +xref: EMAPS:3586928 +relationship: part_of MA:0001593 ! tongue papilla + +[Term] +id: MA:0003179 +name: valve leaflet +xref: EMAPS:3590328 +relationship: part_of MA:0000086 ! heart valve + +[Term] +id: MA:0003180 +name: tricuspid valve leaflet +xref: EMAPS:1863028 +is_a: MA:0003179 ! valve leaflet +relationship: part_of MA:0000090 ! tricuspid valve + +[Term] +id: MA:0003181 +name: testis vasculature +xref: EMAPS:2960328 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0003182 +name: testis coelomic vessel +xref: EMAPS:2960528 +relationship: part_of MA:0003181 ! testis vasculature + +[Term] +id: MA:0003183 +name: testis intersitial vessel +xref: EMAPS:2960728 +relationship: part_of MA:0003181 ! testis vasculature + +[Term] +id: MA:0003184 +name: brain venous system +xref: EMAPS:1863128 +relationship: part_of MA:0002769 ! brain vasculature + +[Term] +id: MA:0003185 +name: brainstem reticular formation +xref: EMAPS:3518828 +relationship: part_of MA:0000169 ! brainstem + +[Term] +id: MA:0003186 +name: CA1 pyramidal cell layer +xref: EMAPS:3519628 +is_a: MA:0000956 ! hippocampus pyramidal layer +relationship: part_of MA:0000950 ! hippocampus CA1 + +[Term] +id: MA:0003187 +name: cerebellum ventricular layer +xref: EMAPS:1779028 +is_a: MA:0000201 ! cerebellar layer + +[Term] +id: MA:0003188 +name: cerebral cortex subventricular zone +xref: EMAPS:3270428 +relationship: part_of MA:0000185 ! cerebral cortex + +[Term] +id: MA:0003189 +name: cerebral cortex ventricular zone +xref: EMAPS:3270728 +relationship: part_of MA:0000185 ! cerebral cortex + +[Term] +id: MA:0003190 +name: forebrain ventricular layer +xref: EMAPS:3292128 +relationship: part_of MA:0000170 ! forebrain + +[Term] +id: MA:0003191 +name: olfactory bulb olfactory nerve layer +xref: EMAPS:3561428 +relationship: part_of MA:0000194 ! main olfactory bulb + +[Term] +id: MA:0003192 +name: spinal cord lateral wall +xref: EMAPS:1757928 +relationship: part_of MA:0000216 ! spinal cord + +[Term] +id: MA:0003193 +name: ventricular layer +relationship: part_of MA:0000167 ! central nervous system + +[Term] +id: MA:0003194 +name: colon mucosa +xref: EMAPS:2737528 +relationship: part_of MA:0000335 ! colon + +[Term] +id: MA:0003195 +name: colon epithelium +xref: EMAPS:1894128 +relationship: part_of MA:0003194 ! colon mucosa + +[Term] +id: MA:0003196 +name: colon lamina propria +xref: EMAPS:2739528 +relationship: part_of MA:0003194 ! colon mucosa + +[Term] +id: MA:0003197 +name: colon muscularis mucosa +xref: EMAPS:2739928 +relationship: part_of MA:0003194 ! colon mucosa + +[Term] +id: MA:0003198 +name: colon muscularis +xref: EMAPS:2738328 +relationship: part_of MA:0000335 ! colon + +[Term] +id: MA:0003199 +name: colon serosa +relationship: part_of MA:0000335 ! colon + +[Term] +id: MA:0003200 +name: colon submucosa +xref: EMAPS:2737928 +relationship: part_of MA:0003198 ! colon muscularis + +[Term] +id: MA:0003201 +name: gut epithelium +xref: EMAPS:3292828 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0003202 +name: gut gland +xref: EMAPS:1881528 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0003203 +name: gut mesentery +xref: EMAPS:3291128 +relationship: part_of MA:0000917 ! gut + +[Term] +id: MA:0003204 +name: foregut epithelium +xref: EMAPS:3292228 +is_a: MA:0003201 ! gut epithelium +relationship: part_of MA:0001526 ! foregut + +[Term] +id: MA:0003205 +name: midgut epithelium +xref: EMAPS:1656928 +is_a: MA:0003201 ! gut epithelium +relationship: part_of MA:0001564 ! midgut + +[Term] +id: MA:0003206 +name: hindgut epithelium +xref: EMAPS:1671728 +is_a: MA:0003201 ! gut epithelium +relationship: part_of MA:0001527 ! hindgut + +[Term] +id: MA:0003207 +name: duodenum mucosa +xref: EMAPS:2723528 +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003208 +name: duodenum epithelium +xref: EMAPS:1907828 +relationship: part_of MA:0003207 ! duodenum mucosa + +[Term] +id: MA:0003209 +name: duodenum lamina propria +xref: EMAPS:2725528 +relationship: part_of MA:0003207 ! duodenum mucosa + +[Term] +id: MA:0003210 +name: duodenum muscularis mucosa +xref: EMAPS:2725928 +relationship: part_of MA:0003207 ! duodenum mucosa + +[Term] +id: MA:0003211 +name: duodenum muscularis +xref: EMAPS:2724328 +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003212 +name: duodenum serosa +xref: EMAPS:2724728 +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003213 +name: duodenum submucosa +xref: EMAPS:2723928 +relationship: part_of MA:0000338 ! duodenum + +[Term] +id: MA:0003214 +name: jejunum mucosa +xref: EMAPS:2710928 +relationship: part_of MA:0000340 ! jejunum + +[Term] +id: MA:0003215 +name: jejunum epithelium +xref: EMAPS:1866828 +relationship: part_of MA:0003214 ! jejunum mucosa + +[Term] +id: MA:0003216 +name: ileum mucosa +xref: EMAPS:3542428 +relationship: part_of MA:0000339 ! ileum + +[Term] +id: MA:0003217 +name: ileum epithelium +xref: EMAPS:3542328 +relationship: part_of MA:0003216 ! ileum mucosa + +[Term] +id: MA:0003218 +name: rectum mucosa +xref: EMAPS:2708128 +relationship: part_of MA:0000336 ! rectum + +[Term] +id: MA:0003219 +name: rectum epithelium +xref: EMAPS:1789828 +relationship: part_of MA:0003218 ! rectum mucosa + +[Term] +id: MA:0003220 +name: jaw epithelium +xref: EMAPS:3290428 +relationship: part_of MA:0001905 ! jaw + +[Term] +id: MA:0003221 +name: incisor dental pulp +xref: EMAPS:3542928 +is_a: MA:0001599 ! dental pulp +relationship: part_of MA:0000349 ! incisor + +[Term] +id: MA:0003222 +name: molar dental pulp +xref: EMAPS:3557628 +is_a: MA:0001599 ! dental pulp +relationship: part_of MA:0000350 ! molar + +[Term] +id: MA:0003223 +name: incisor epithelium +xref: EMAPS:3289028 +is_a: MA:0003151 ! tooth epithelium +relationship: part_of MA:0000349 ! incisor + +[Term] +id: MA:0003224 +name: molar epithelium +xref: EMAPS:3287828 +is_a: MA:0003151 ! tooth epithelium +relationship: part_of MA:0000350 ! molar + +[Term] +id: MA:0003225 +name: incisor dental lamina +xref: EMAPS:3289628 +is_a: MA:0001597 ! dental lamina +relationship: part_of MA:0003223 ! incisor epithelium + +[Term] +id: MA:0003226 +name: molar dental lamina +xref: EMAPS:3287928 +is_a: MA:0001597 ! dental lamina +relationship: part_of MA:0003224 ! molar epithelium + +[Term] +id: MA:0003227 +name: incisor enamel organ +xref: EMAPS:3289528 +is_a: MA:0001604 ! tooth enamel organ +relationship: part_of MA:0003223 ! incisor epithelium + +[Term] +id: MA:0003228 +name: molar enamel organ +xref: EMAPS:3288028 +is_a: MA:0001604 ! tooth enamel organ +relationship: part_of MA:0003224 ! molar epithelium + +[Term] +id: MA:0003229 +name: incisor mesenchyme +xref: EMAPS:3289428 +is_a: MA:0003152 ! tooth mesenchyme +relationship: part_of MA:0000349 ! incisor + +[Term] +id: MA:0003230 +name: molar mesenchyme +xref: EMAPS:3288128 +is_a: MA:0003152 ! tooth mesenchyme +relationship: part_of MA:0000350 ! molar + +[Term] +id: MA:0003231 +name: incisor dental papilla +xref: EMAPS:3289328 +is_a: MA:0001598 ! dental papilla +relationship: part_of MA:0003229 ! incisor mesenchyme + +[Term] +id: MA:0003232 +name: molar dental papilla +xref: EMAPS:3288228 +is_a: MA:0001598 ! dental papilla +relationship: part_of MA:0003230 ! molar mesenchyme + +[Term] +id: MA:0003233 +name: urinary system mesentery +xref: EMAPS:1736728 +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0003234 +name: urogenital mesentery +xref: EMAPS:1736828 +relationship: part_of MA:0003233 ! urinary system mesentery + +[Term] +id: MA:0003235 +name: urorectal septum +xref: EMAPS:1738028 +relationship: part_of MA:0000325 ! urinary system + +[Term] +id: MA:0003236 +name: mesovarium +xref: EMAPS:1796128 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003237 +name: rete ovarii of ovary +xref: EMAPS:1796628 +relationship: part_of MA:0000384 ! ovary + +[Term] +id: MA:0003238 +name: mesorchium +xref: EMAPS:1797128 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003239 +name: Mullerian tubercle +xref: EMAPS:1832828 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003240 +name: mediastinum testis +xref: EMAPS:1833128 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0003241 +name: female cystic vesicular appendage +xref: EMAPS:1897828 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003242 +name: vagina upper part +xref: EMAPS:1898728 +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0003243 +name: vagina lower part +xref: EMAPS:1899928 +relationship: part_of MA:0000394 ! vagina + +[Term] +id: MA:0003244 +name: suspensory ligament of ovary +xref: EMAPS:1908528 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003245 +name: appendix epididymis +xref: EMAPS:1908628 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003246 +name: appendix testis +xref: EMAPS:1908728 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003247 +name: ejaculatory duct +xref: EMAPS:1908828 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003248 +name: gubernaculum +xref: EMAPS:1908928 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003249 +name: female inguinal canal +xref: EMAPS:1917128 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003250 +name: female inguinal ring +xref: EMAPS:1917228 +relationship: part_of MA:0000381 ! female reproductive system + +[Term] +id: MA:0003251 +name: female internal inguinal ring +xref: EMAPS:1917328 +is_a: MA:0003250 ! female inguinal ring + +[Term] +id: MA:0003252 +name: female external inguinal ring +xref: EMAPS:1917428 +is_a: MA:0003250 ! female inguinal ring + +[Term] +id: MA:0003253 +name: tunica vaginalis testis +xref: EMAPS:1917928 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0003254 +name: tunica albuginea of testis +xref: EMAPS:1928928 +relationship: part_of MA:0000411 ! testis + +[Term] +id: MA:0003255 +name: crus penis +xref: EMAPS:1929428 +relationship: part_of MA:0000408 ! penis + +[Term] +id: MA:0003256 +name: male inguinal canal +xref: EMAPS:2691328 +relationship: part_of MA:0000396 ! male reproductive system + +[Term] +id: MA:0003257 +name: plantaris +xref: EMAPS:3625428 +is_a: MA:0000678 ! lower leg muscle + +[Typedef] +id: part_of +name: part of +is_transitive: true + diff --git a/notebooks/input/xao.obo b/notebooks/input/xao.obo new file mode 100644 index 000000000..4865f512c --- /dev/null +++ b/notebooks/input/xao.obo @@ -0,0 +1,19696 @@ +format-version: 1.2 +data-version: releases/2021-03-04 +date: 04:03:2021 16:30 +saved-by: eriksegerdell +subsetdef: anatomical_site_slim "Anatomical Site slim" +subsetdef: frequent_anatomy_items "Frequently Used Anatomy slim" +subsetdef: organism_views "Organism View slim" +subsetdef: sectional_anatomy_items "Sectional Anatomy Item slim" +synonymtypedef: PLURAL "PLURAL" +default-namespace: xenopus_anatomy +namespace-id-rule: * XAO:$sequence(7,5000,9999999)$ +treat-xrefs-as-genus-differentia: CARO part_of NCBITaxon:8353 +treat-xrefs-as-genus-differentia: CL part_of NCBITaxon:8353 +treat-xrefs-as-genus-differentia: GO part_of NCBITaxon:8353 +treat-xrefs-as-genus-differentia: UBERON part_of NCBITaxon:8353 +remark: Citation for XAO v1 by Xenbase: Segerdell E, Bowes JB, Pollet N, Vize PD; BMC Dev Biol 2008 8:92; PMID:18817563. +remark: Citation for XAO v3 by Xenbase: Segerdell E, Ponferrada VG, James-Zorn C, Burns KA, Fortriede JD, Dahdul WM, Vize PD, Zorn AM; J Biomed Semantics 2013 4(1):31; PMID:24139024. +remark: Supported by NIH R01 HD045776 and NICHD P41 HD064556. +remark: Version: 9.1 +ontology: xao +property_value: http://purl.org/dc/elements/1.1/description "XAO represents the anatomy and development of the African frogs Xenopus laevis and tropicalis." xsd:string +property_value: http://purl.org/dc/elements/1.1/title "Xenopus Anatomy Ontology" xsd:string +property_value: http://purl.org/dc/terms/license https://creativecommons.org/licenses/by/3.0/ xsd:string + +[Term] +id: XAO:0000000 +name: Xenopus anatomical entity +def: "An entity that is either an individual member of Xenopus or constitutes the structural organization of an individual member of Xenopus." [CARO:0000000, XAO:EJS] +xref: CARO:0000000 + +[Term] +id: XAO:0000001 +name: ectoderm +def: "Primary germ layer that is the outer of the embryo's germ layers and gives rise to epidermis and neural tissue." [http://dictionary.reference.com/medical/ectoderm] +subset: frequent_anatomy_items +xref: UBERON:0000924 +is_a: XAO:0003011 ! primary germ layer +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000002 +name: fin +def: "Surface structure that has an important role in tadpole locomotion. It starts to develop along the trunk and tail of the embryo at the tail bud stage and continues to grow until the start of metamorphosis when it begins to regress. It consists of flattened epidermal cells elevated into a keel-like structure by a supporting core of mesenchyme and extracellular matrix." [PMID:15188431] +subset: frequent_anatomy_items +xref: UBERON:0008897 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000003 +name: outer fin +def: "Part of the fin consisting of flattened epidermal cells elevated into a keel-like structure." [PMID:15188431] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000002 ! fin +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000004 +name: inner fin +def: "Part of the fin consisting of a supporting core of mesenchyme and extracellular matrix." [PMID:15188431] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000002 ! fin +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000005 +name: olfactory placode +def: "A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory epithelium of the nasal cavity." [http://www.merriam-webster.com/medlineplus/olfactory+placode] +synonym: "nasal placode" RELATED [] +xref: UBERON:0003050 +is_a: XAO:0004620 ! neurogenic placode +relationship: develops_from XAO:0000041 ! epidermis inner layer +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: develops_from XAO:0004206 ! anterior placodal area +relationship: develops_from XAO:0004209 ! anterior neural ridge +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000006 +name: otic vesicle +alt_id: XAO:0000184 +def: "The saccular invagination of ectoderm from which the vertebrate inner ear develops." [UBERON:0003051] +subset: frequent_anatomy_items +synonym: "ear" BROAD [] +synonym: "ear vesicle" RELATED [] +synonym: "otocyst" RELATED [] +xref: UBERON:0003051 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000223 ! otic placode +relationship: end_stage XAO:1000070 ! NF stage 58 +relationship: part_of XAO:0003195 ! vestibuloauditory system +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000007 +name: lower eyelid +def: "A surface structure consisting of a set of membranes that cover and protect the eye." [http://en.wikipedia.org/wiki/Frog] +synonym: "ventral eyelid" EXACT [] +xref: UBERON:0001713 +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000074 ! NF stage 62 + +[Term] +id: XAO:0000008 +name: lens +def: "Transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina." [http://en.wikipedia.org/wiki/Lens_(anatomy)] +xref: UBERON:0000965 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000240 ! lens placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000009 +name: retina +def: "Sensory membrane that lines the posterior chamber of the eye and functions as the immediate instrument of vision by receiving the image formed by the lens and converting it into chemical and nervous signals which reach the brain by way of the optic nerve." [http://www.merriam-webster.com/medlineplus/retina] +xref: UBERON:0000966 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000010 +name: brain +def: "Organ that is a component of the central nervous system and is responsible for the coordination and control of bodily activities and the interpretation of information from the senses. It appears when the neural tube segregates in forebrain, midbrain, and hindbrain at NF stage 22. The general pattern of the brain has been mainly established at NF stage 28. Yolky material is consumed and the fibre tracts and later the commissures develop. In general all of its parts are well developed at NF stage 53 and later development consists mainly of growth and some further cytological differentiation. In the period of metamorphosis only topographical changes take place." [http://dictionary.reference.com/medical/brain, ISBN:0815318960] +subset: frequent_anatomy_items +xref: UBERON:0000955 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0003204 ! neural tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000215 ! central nervous system +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000011 +name: forebrain +def: "The part of the brain that is the anterior of its three primary divisions and that includes the telencephalon and diencephalon." [http://www.merriam-webster.com/medlineplus/forebrain] +synonym: "prosencephalon" RELATED [] +xref: UBERON:0001890 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000307 ! anterior neural tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000012 +name: telencephalon +def: "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres." [AAO:0010479] +xref: UBERON:0001893 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000011 ! forebrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000013 +name: diencephalon +def: "The more posterior and ventral of two forebrain neuromeres, the other being the telencephalon; major derivatives are the eye vescile, the brain pretectal region, the thalamus, hypothalamus, and epithalamus (including the habenula and epiphysis)." [XAO:curators] +xref: UBERON:0001894 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000011 ! forebrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000014 +name: midbrain +def: "Middle part of the brain composed of the optic tectum and penducular region." [AAO:0010149] +synonym: "mesencephalon" RELATED [] +xref: UBERON:0001891 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000307 ! anterior neural tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000015 +name: hindbrain +def: "The part of the brain that is the posterior of its three primary divisions." [http://www.merriam-webster.com/medlineplus/hindbrain] +synonym: "rhombencephalon" RELATED [] +xref: UBERON:0002028 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000250 ! posterior neural tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000016 +name: midbrain-hindbrain boundary +def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [UBERON:0003052] +synonym: "isthmic organizer territory" RELATED [] +synonym: "isthmus" RELATED [] +synonym: "MHB" EXACT [] +xref: UBERON:0003052 +is_a: XAO:0004003 ! anatomical line +relationship: develops_from XAO:0004086 ! presumptive midbrain-hindbrain boundary +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000017 +name: hypophysis +alt_id: XAO:0000161 +def: "An endocrine gland, located ventral to the diencephalon, that secretes hormones that regulate many other glands." [UBERON:0000007] +synonym: "Hyp" EXACT [] +synonym: "pituitary" RELATED [] +synonym: "pituitary gland" RELATED [] +xref: UBERON:0000007 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000267 ! hypophyseal primordium +relationship: develops_from XAO:0004208 ! adenohypophyseal placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000011 ! forebrain +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000018 +name: genital ridge +def: "Portion of tissue that is the precursor to the gonads." [http://en.wikipedia.org/wiki/Gonadal_ridge] +xref: UBERON:0005294 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:1000064 ! NF stage 52 +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000020 +name: spinal cord +def: "Elongated, approximately cylindrical part of the central nervous system that lies in the vertebral canal and from which the spinal nerves emerge." [http://dictionary.reference.com/medical/spinal+cord] +xref: UBERON:0002240 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000250 ! posterior neural tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000215 ! central nervous system +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000021 +name: ventricular zone +def: "Proliferative region that is part of the ventricular system of the brain." [VHOG:0001224] +subset: anatomical_site_slim +xref: UBERON:0003053 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000022 +name: roof plate +def: "Organizing center located at the dorsal midline of the neural tube that influences the development of the nervous system, controlling the specification and differentiation of dorsal neuronal cell types." [PMID:15378040] +synonym: "roofplate" EXACT [] +synonym: "spinal cord roof" RELATED [] +xref: UBERON:0005724 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005241 ! superficial layer of neurectoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000023 +name: skin +def: "Surface structure that consists of the external membranous integument of the animal." [http://dictionary.reference.com/medical/skin] +synonym: "integument" RELATED [] +xref: UBERON:0002097 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000028 ! epidermis +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000176 ! dermal system +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000024 +name: mandibular crest +def: "The most anterior of the migrating cranial neural crest streams, running along the posterior edge of the eye primordium, and in later stages, below the eye and to the border of the cement gland. The mandibular stream is the first to initiate CNC cell migration." [PMID:21490068] +xref: UBERON:0007098 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0001001 ! cranial neural crest +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: part_of XAO:0001001 ! cranial neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000025 +name: hyoid crest +def: "The second most anterior of the migrating cranial neural crests streams, it lays between the mandibular and anterior branchial crest streams." [PMID:21490068] +synonym: "hyoid neural crest" EXACT [] +xref: UBERON:0007099 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0001001 ! cranial neural crest +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0001001 ! cranial neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000026 +name: branchial crest +def: "The most posterior segments of the population of migratory cells of the cranial neural crest, contributing to the branchial arches 3 and 4. Branchial crest cells migrate in two distinct streams referred to as the anterior and posterior branchial crest." [XAO:CJZ] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0001001 ! cranial neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000027 +name: cranial ganglion +def: "Ganglion that is located in the head." [XAO:EJS, ZFA:0000013] +synonym: "cranial ganglia" RELATED PLURAL [] +xref: UBERON:0001714 +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000028 +name: epidermis +def: "The outer epithelial layer of the external integument of the body that is derived from the primative or embryonic ectoderm." [AAO:0000143] +subset: frequent_anatomy_items +synonym: "skin" BROAD [] +xref: UBERON:0001003 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004091 ! non-neural ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000001 ! ectoderm +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000029 +name: epidermis outer layer +def: "The outermost layer of the epidermis, the multilayered epithelium derived from the ectoderm." [XAO:curators] +synonym: "epidermis epithelial layer" RELATED [] +synonym: "periderm" RELATED [] +xref: UBERON:0003055 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000030 +name: vitelline membrane +def: "The membrane enveloping the egg or oocyte, lying immediately outside the plasmalemma. It is formed while the oocyte is in the ovary and it separates from the egg to form the fertilization membrane." [AAO:0010332, XAO:curators] +xref: UBERON:0003125 +is_a: XAO:0004005 ! extraembryonic structure +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: part_of XAO:0000035 ! zygote +relationship: start_stage XAO:1000092 ! mature egg stage + +[Term] +id: XAO:0000031 +name: ciliated epidermal cell +def: "Cell type that has motile cilia and populates the skin of the embryo, arranged in the surface layer of the non-neural ectoderm in an ordered distribution." [PMID:10518489] +synonym: "ciliated cell" BROAD [] +synonym: "epidermal ciliary cell" EXACT [] +xref: CL:0007018 +is_a: XAO:0004621 ! epidermal cell +is_a: XAO:0005017 ! ciliated cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000032 +name: stomodeal-hypophyseal primordium +def: "An anterior thickening of the sensorial layer of ectoderm, just above the cement gland. The hypophyseal layer separates from the stomodeal layer at NF stage 29 and 30, and when contacted by a protrusion of the foregut, the stomodeal layer will rupture to form the mouth opening at NF stage 39 and 40." [XAO:curators] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000001 ! ectoderm +relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000033 +name: cement gland +def: "A simple mucus-secreting structure that is positioned at the front of the embryo, attaches the newly hatched embryo to a support before the hatchling can swim well or feed, and marks the anterior-most dorsal ectoderm." [PMID:8787748] +subset: frequent_anatomy_items +xref: UBERON:0005093 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000049 ! cement gland primordium +relationship: end_stage XAO:1000062 ! NF stage 50 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000034 +name: hatching gland +def: "A Y-shaped array of unicelluar glands on the top of the head, the open end of which faces anteriorly, that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching. Presumptive cells of the hatching gland are present by the end of gastrualtion (NF stage 12.5) and differentiated cells start to form after neurulation is complete (NF stage 21)." [XAO:curators] +synonym: "frontal gland" RELATED [] +xref: UBERON:0002538 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0004394 ! hatching gland primordium +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000035 +name: zygote +def: "Cell resulting from the fusion of male and female gametes at fertilization." [http://dictionary.reference.com/medical/zygote] +synonym: "fertilized egg" EXACT [] +xref: CL:0000365 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000036 +name: animal cap +def: "Ectodermal roof of the blastocoel." [XAO:curators] +synonym: "animal ectoderm" RELATED [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) + +[Term] +id: XAO:0000037 +name: animal cap inner layer +def: "Sensorial layer of blastocoel roof ectoderm." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000036 ! animal cap +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0000038 +name: animal cap outer layer +def: "Superficial layer of blastocoel roof ectoderm." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000036 ! animal cap +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0000039 +name: obsolete anatomical site +is_obsolete: true +consider: XAO:0003186 + +[Term] +id: XAO:0000040 +name: head region +def: "The anterior-most third of the embryo, formed from the development of the head outgrowth at NF stage 21." [XAO:curators] +subset: anatomical_site_slim +xref: UBERON:0001444 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000041 +name: epidermis inner layer +def: "A distinct layer of the epidermal cells beneath the outermost layer of epidermis, the multilayered epithelium derived from the ectoderm." [XAO:curators] +synonym: "epidermis sensorial layer" RELATED [] +synonym: "stratum germinativum" RELATED [] +xref: UBERON:0002025 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000042 +name: neuroectoderm +def: "Embryonic ectoderm that gives rise to nervous tissue." [http://www.merriam-webster.com/medlineplus/neuroectoderm] +synonym: "neural ectoderm" RELATED [] +synonym: "neurectoderm" EXACT [] +synonym: "presumptive central nervous system" RELATED [] +xref: UBERON:0002346 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000043 +name: neuroectoderm outer layer +def: "Superficial neuroectoderm layer consisting of horizontally flattened, pigmented cells." [PMID:2642003] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000044 +name: neuroectoderm inner layer +def: "Deep neuroectoderm layer consisting of densely packed, cylindrical, unpigmented cells." [PMID:2642003] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000045 +name: pre-chordal neural plate +def: "The portion of neural plate anterior to the mid-hindbrain junction." [XAO:curators] +synonym: "anterior neural plate" RELATED [] +xref: UBERON:0003056 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000046 +name: chordal neural plate +def: "The portion of neural plate posterior to the mid-hindbrain junction." [XAO:curators] +synonym: "posterior neural plate" RELATED [] +xref: UBERON:0003057 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000047 +name: notoplate +def: "Region of the neural plate overlying the notochord." [http://www.encyclo.co.uk/define/Notoplate] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0000048 +name: neural crest +def: "A group of ectoderm cells that delaminate from the area between the neuroectoderm/non-neural ectoderm domains. They undergo epithelial-to-mesenchymal tranformation (EMT) and migrate to give several different lineages of adult cells. Originating from different positions along the anterior-posterior axis, they develop into various tissues. These regions of neural crest can be divided into five main functional domains, which include the cranial, trunk, vagal and sacral neural crest, and cardiac neural crest. Neural crest cells are considered multipotent, and as they have the limited capacity for self renewal, they are regarded as stem cell-like." [AAO:0010578, XAO:CJZ] +subset: frequent_anatomy_items +synonym: "NC" EXACT [] +synonym: "neural crest material" RELATED [] +xref: UBERON:0002342 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm +relationship: develops_from XAO:0004103 ! chordal neural plate border +relationship: develops_from XAO:0004104 ! neural plate border +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000049 +name: cement gland primordium +def: "The thickening of the epithelial layer of the ectoderm, with corresponding dark pigmentation, on the anterior dorso-ventral surface of the embryo." [ISBN:0070179778] +synonym: "adhesive organ primordium" EXACT [] +synonym: "cement gland" BROAD [] +synonym: "cement gland anlage" EXACT [] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000050 +name: mesoderm +def: "Primary germ layer that is the middle of the embryo's germ layers." [http://dictionary.reference.com/medical/mesoderm] +subset: frequent_anatomy_items +synonym: "mesodermal mantle" RELATED [] +xref: UBERON:0000926 +is_a: XAO:0003011 ! primary germ layer +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000051 +name: dorsal aorta +def: "Principal unpaired, median artery of the trunk, extending into the tail as the caudal artery." [ISBN:0226557634] +synonym: "aorta dorsalis" EXACT [] +xref: UBERON:0005805 +is_a: XAO:0003010 ! aorta +relationship: develops_from XAO:0005019 ! paired dorsal aorta +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000052 +name: cardinal vein +def: "The paired main vein, departing from the sinus venous, the fused heart primordium, it runs posteriorly down length of the embryo." [XAO:curators] +xref: UBERON:0004344 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000053 +name: head mesoderm +def: "The mesoderm of the head." [XAO:curators] +xref: UBERON:0006904 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000079 ! prechordal plate +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000050 ! mesoderm +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0000054 +name: trunk region +def: "The anatomical region of the body posterior to the head and anterior to the tail." [XAO:EJS] +subset: anatomical_site_slim +xref: UBERON:0002100 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000055 +name: notochord +def: "A longitudinal flexible rod of cells that in the embryo forms the supporting axis of the body. It degenerates, beginning anteriorly, at NF stage 46. Its posterior portion is greatly reduced by NF stage 55 and the entire structure is gone by NF stage 65." [http://www.merriam-webster.com/medlineplus/notochord, ISBN:0815318960] +subset: frequent_anatomy_items +xref: UBERON:0002328 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000205 ! axial mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0000056 +name: hypochord +def: "Transient structure that lies immediately ventral to the notochord in the embryo, likely required for the formation of the dorsal aorta. A slight depression marks the future hypochord at NF stage 20 and its segregation from the dorsal endoderm begins at NF stage 24. It progresses from anterior to posterior and is complete by NF stage 28. At NF stage 32 it is present as a dorso-laterally flattened ribbon of yolk-laden cells. It degenerates by apoptosis and by NF stage 43 is no longer detectable as a distinct structure in the trunk region of the tadpole. The most posterior hypochord persists and begins to ossify, fusing with the coccyx to form the urostyle in the pelvic girdle around NF stage 63." [ISBN:0815318960, PMID:10648245] +synonym: "ipochord" EXACT [] +synonym: "subnotochordal rod" RELATED [PMID:10648245] +xref: UBERON:0003058 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000075 ! NF stage 63 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000057 +name: presomitic mesoderm +def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." [UBERON:0003059] +synonym: "somitogenic mesoderm" RELATED [] +xref: UBERON:0003059 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000259 ! paraxial mesoderm +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000259 ! paraxial mesoderm +relationship: part_of XAO:0004042 ! muscular system +relationship: start_stage XAO:1000024 ! NF stage 14 + +[Term] +id: XAO:0000058 +name: somite +def: "Any of the approximately 45 bilaterally paired blocks of mesoderm cells, lying on either side of the notochord and neural tube, and forming sequentially starting at the head during development of the embryo. Together they give rise to the axial skeleton (from the sclerotome), associated musculature (from the myotome), and dermis (from the dermatome)." [http://dictionary.reference.com/medical/somite, XAO:curators] +subset: frequent_anatomy_items +synonym: "somites" RELATED PLURAL [] +synonym: "somitic mesoderm" RELATED [] +xref: UBERON:0002329 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000057 ! presomitic mesoderm +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000050 ! mesoderm +relationship: part_of XAO:0004042 ! muscular system +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000059 +name: obsolete pronephros +is_obsolete: true +replaced_by: XAO:0002000 + +[Term] +id: XAO:0000061 +name: obsolete pronephric capsule +is_obsolete: true +consider: XAO:0000318 + +[Term] +id: XAO:0000062 +name: pronephric nephrostome +def: "Any of the ciliated tubules that collect the glomeral filtrate, passing it through to the pronephric tubules." [XAO:CJZ] +synonym: "nephrostome" EXACT [] +xref: UBERON:0005308 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000264 ! pronephric mesenchyme +relationship: end_stage XAO:1000071 ! NF stage 59 +relationship: part_of XAO:0002000 ! pronephric kidney +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000063 +name: pronephric duct +def: "Duct that drains urine from the pronephros and connects it to the cloaca. It is thought that the pronephric duct may play a key role in the induction of the mesonephric (adult) kidney. The most anterior part of the pronephric duct shows distinct gene expression patterns and is sometimes referred to as DT2." [PMID:8365571, XAO:CJZ] +synonym: "common tubule" RELATED [] +synonym: "connecting tubule" RELATED [] +synonym: "distal tubule segment 2" EXACT [] +synonym: "DT2" EXACT [] +synonym: "nephric duct" EXACT [] +synonym: "Wolffian duct" EXACT [] +xref: UBERON:0003060 +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000264 ! pronephric mesenchyme +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0002000 ! pronephric kidney +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000064 +name: heart +def: "A myogenic muscular organ found in the cardiovascular system. It is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions. It is composed of cardiac muscle, which is an involuntary striated muscle tissue found only in this organ, and connective tissue. It is ultimately composed of three chambers (two atria and one ventricle), occupying a ventral position within the chest of the mature tadpole/frog." [PMID:17194606, UBERON:0000948] +subset: frequent_anatomy_items +xref: UBERON:0000948 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000336 ! heart primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000065 +name: myocardium +def: "Cardiac muscle constituting the middle layer of the heart." [AAO:0010410] +synonym: "cardiac muscle" RELATED [] +xref: UBERON:0002349 +is_a: XAO:0000172 ! muscle +relationship: develops_from XAO:0000336 ! heart primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000066 +name: endocardium +def: "Part of the heart composed of thin serous membrane and endothelial tissue, that lines the interior of the heart." [AAO:0010408] +xref: UBERON:0002165 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000336 ! heart primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000067 +name: ventral blood island +def: "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates." [PMID:9618755] +synonym: "blood island" BROAD [] +synonym: "VBI" EXACT [] +synonym: "ventral lateral plate mesoderm" BROAD [] +xref: UBERON:0003061 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000311 ! lateral plate mesoderm +relationship: develops_from XAO:0004473 ! ventral mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000026 ! NF stage 16 + +[Term] +id: XAO:0000068 +name: marginal zone +def: "Region of intermediate pigmentation between the pigmented animal hemisphere and the unpigmented vegetal hemisphere of the egg." [http://worms.zoology.wisc.edu/frogs/glossary.html] +xref: UBERON:0004879 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000069 +name: ventral marginal zone +def: "Embryonic tissue region that will make the ventral mesoderm." [XAO:EJS] +synonym: "VMZ" EXACT [] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000070 +name: ventro-lateral marginal zone +def: "Region of the marginal zone extending from the ventral to lateral surface." [XAO:EJS] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000071 +name: dorso-lateral marginal zone +def: "Region of the marginal zone extending from the dorsal to lateral surface." [XAO:EJS] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000072 +name: dorsal marginal zone +def: "Marginal zone that is a key embryonic tissue region of the early gastrula stage embryo and that houses the Spemann-Mangold organizer." [PMID:17368611] +synonym: "DMZ" EXACT [PMID:17368611] +synonym: "organizer" RELATED [] +synonym: "Spemann organizer" RELATED [] +xref: UBERON:0003062 +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000073 +name: obsolete deep (mesenchymal) layer +is_obsolete: true + +[Term] +id: XAO:0000074 +name: involuting marginal zone +def: "Portion of the marginal zone of the embryo that turns inside the embryo during involution." [http://worms.zoology.wisc.edu/frogs/glossary.html] +synonym: "IMZ" EXACT [] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000075 +name: involuting marginal zone mesenchymal layer +def: "Deep layers of the IMZ consisting of prospective migrating mesodermal cells (which will migrate into the interior and form the leading edge of the mesodermal mantle) and prospective converging and extending mesoderm." [ISBN:0123646200] +synonym: "deep involuting marginal zone" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000074 ! involuting marginal zone +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000076 +name: involuting marginal zone epithelial layer +def: "Layer of prospective mesoderm in the IMZ that will form the roof of the archenteron." [XAO:curators] +synonym: "involuting superfical mesdoderm" RELATED [] +synonym: "SM" RELATED [] +synonym: "superficial involuting marginal zone" RELATED [] +synonym: "superficial mesoderm" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000074 ! involuting marginal zone +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000077 +name: bottle cell +def: "Cell type that is first to migrate inwards at the blastopore during gastrulation." [http://dictionary.reference.com/medical/bottle+cell] +is_a: XAO:0003244 ! gastrula cell +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000078 +name: blastopore lip +def: "The edge of the blastopore. Local invagination is caused by narrowing of bottle cells at the exterior edge of the blastula." [ISBN:0387537406] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000208 ! blastopore +relationship: start_stage XAO:1000030 ! NF stage 10.25 + +[Term] +id: XAO:0000079 +name: prechordal plate +def: "Mesodermal structure that lies anterior to the notochord and gives rise to head mesoderm." [VHOG:0000086] +xref: UBERON:0003063 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000205 ! axial mesoderm +relationship: start_stage XAO:1000022 ! NF stage 12 + +[Term] +id: XAO:0000080 +name: forelimb region +def: "The region from which the forelimb develops, first recognizable at NF stage 48, and distinct by NF stage 49." [XAO:curators] +subset: anatomical_site_slim +synonym: "fore limb region" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0000081 +name: hindlimb region +def: "The region from which the hindlimb develops, first recognizable as a slight concentration of mesenchymal cells dorsal and lateral to the anal tube at NF stage 43. The epidermal layers thicken dramatically through to NF stage 48, and become vascularised by NF stage 49." [XAO:curators] +subset: anatomical_site_slim +synonym: "hind limb region" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000082 +name: circumblastoporal collar +def: "Embryonic structure that develops around the closed blastopore." [PMID:22138030] +synonym: "circumblastoporal region" RELATED [] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000088 ! upper blastopore lip +relationship: develops_from XAO:0000089 ! lower blastopore lip +relationship: end_stage XAO:1000036 ! NF stage 20 +relationship: start_stage XAO:1000022 ! NF stage 12 + +[Term] +id: XAO:0000083 +name: involuted dorsal mesoderm +def: "Dorsal mesoderm that has grown and curled inward during gastrulation." [http://medical-dictionary.thefreedictionary.com/involution] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000025 ! NF stage 15 +relationship: part_of XAO:0000082 ! circumblastoporal collar +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000084 +name: involuted ventral mesoderm +def: "Ventral mesoderm that has grown and curled inward during gastrulation." [http://medical-dictionary.thefreedictionary.com/involution] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000025 ! NF stage 15 +relationship: part_of XAO:0000082 ! circumblastoporal collar +relationship: start_stage XAO:1000031 ! NF stage 10.5 + +[Term] +id: XAO:0000085 +name: intermediate mesoderm +def: "Mesoderm layer between somite and lateral plate. All components of the pronephric kidney arise from this." [AAO:0010575, XAO:CJZ] +xref: UBERON:0003064 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000050 ! mesoderm +relationship: develops_from XAO:0000311 ! lateral plate mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000050 ! mesoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000086 +name: ciliary marginal zone +def: "The region at the periphery of the retina where retinal stem cells are located. It is spatially ordered with respect to cellular development and differentiation, with the youngest and least-determined stem cells closest to the periphery, the proliferative retinoblasts in the middle, and postmitotic cells at the central edge." [PMID:15844194] +xref: UBERON:0003065 +is_a: XAO:0004122 ! proliferative region +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000087 +name: tail region +def: "The anatomical region of the body posterior to the tail." [XAO:EJS] +subset: anatomical_site_slim +xref: UBERON:0006071 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0000088 +name: upper blastopore lip +def: "Dorsal part of the blastopore lip, which forms as a result of the contraction of bottle cells." [XAO:EJS] +synonym: "dorsal blastopore lip" RELATED [] +synonym: "organizer" BROAD [] +synonym: "Spemann organizer" BROAD [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000078 ! blastopore lip +relationship: start_stage XAO:1000030 ! NF stage 10.25 + +[Term] +id: XAO:0000089 +name: lower blastopore lip +def: "Ventral part of the blastopore lip, which forms as a result of the contraction of bottle cells." [XAO:EJS] +synonym: "ventral blastopore groove" RELATED [] +synonym: "ventral blastopore lip" RELATED [] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000078 ! blastopore lip +relationship: start_stage XAO:1000030 ! NF stage 10.25 + +[Term] +id: XAO:0000090 +name: endoderm +def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [http://dictionary.reference.com/medical/endoderm] +subset: frequent_anatomy_items +synonym: "entoderm" RELATED [] +xref: UBERON:0000925 +is_a: XAO:0003011 ! primary germ layer +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000091 +name: head endoderm +def: "The endoderm of the head." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000090 ! endoderm +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000092 +name: archenteron +def: "The cavity of the gastrula forming a primitive gut. At NF stage 20-21 its wide canal becomes dorso-ventrally compressed and narrowed in the future trunk region so that a subdivision into a foregut, a midgut and a hindgut with protruding endodermal mass becomes manifest." [http://www.merriam-webster.com/medlineplus/archenteron, ISBN:0815318960] +synonym: "gastrocoel" RELATED [] +xref: UBERON:0004735 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000093 +name: archenteron floor +def: "The layer of cells forming the ventral surface of the archenteron space of the embryo." [PMID:17540356] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000281 ! vegetal yolk mass +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000092 ! archenteron +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000094 +name: gastrocoel roof plate +def: "A transient ciliated epithelium that arises from the involuting superficial mesoderm, forming the dorsal surface of the archenteron space of the embryo." [PMID:17540356, XAO:EJS] +synonym: "archenteron roof" EXACT [] +synonym: "archenteron roof plate" EXACT [] +synonym: "gastrocoel roof" EXACT [] +synonym: "GRP" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000076 ! involuting marginal zone epithelial layer +relationship: develops_from XAO:0000077 ! bottle cell +relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000092 ! archenteron +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000095 +name: lateral line system +def: "Sensory system that has as it parts the sense organs that detect vibrations carried through water, develops during late tailbud stage, and persists in the adult bearing elaborate dorsal and ventral components. It develops from a specialized series of dorsolateral ectodermal placodes named lateral line placodes." [AAO:0000975, ISBN:0471209627, ISBN:0815318960] +synonym: "lateral line stitches" RELATED [] +synonym: "lateral-line organs" RELATED [] +xref: UBERON:0002540 +is_a: XAO:0003194 ! sensory system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000096 +name: pharyngeal arch +def: "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [http://www.merriam-webster.com/medlineplus/branchial+arch] +subset: frequent_anatomy_items +synonym: "pharyngeal arches" RELATED PLURAL [] +synonym: "visceral arch" RELATED [] +xref: UBERON:0002539 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000097 +name: mandibular arch +def: "The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [XAO:EJS] +synonym: "first visceral arch" RELATED [] +xref: UBERON:0004362 +is_a: XAO:0000096 ! pharyngeal arch +relationship: develops_from XAO:0000102 ! visceral pouch 1 +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003176 ! splanchnocranium +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000098 +name: hyoid arch +def: "The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo." [XAO:EJS] +synonym: "second visceral arch" RELATED [] +xref: UBERON:0003066 +is_a: XAO:0000096 ! pharyngeal arch +relationship: develops_from XAO:0000247 ! visceral pouch 2 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000099 +name: branchial arch +def: "Structures that develop from the pharyngeal arches. Pharyngeal arches are anlage for a multitude of structures. Each pharyngeal arch has a cartilaginous stick, a muscle component which differentiates from the cartilaginous tissue, an artery, and a cranial nerve. Each of these is surrounded by mesenchyme. Arches do not develop simultaneously, but instead possess a staggered development." [ISBN:0023771100] +synonym: "branchial arches" RELATED PLURAL [] +xref: UBERON:0008896 +is_a: XAO:0000096 ! pharyngeal arch +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000100 +name: cardiovascular system +def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088] +xref: UBERON:0004535 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000101 +name: liver diverticulum +def: "An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Its anterior portion gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder, hepato-pancreatic duct, hepato-pancreatic progenitor cells and the bile duct." [UBERON:0008835] +xref: UBERON:0008835 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000092 ! archenteron +relationship: develops_from XAO:0004513 ! foregut endoderm +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000024 ! NF stage 14 + +[Term] +id: XAO:0000102 +name: visceral pouch 1 +def: "First of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634] +synonym: "first visceral pouch" EXACT [] +xref: UBERON:0007122 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000103 +name: midgut +def: "Middle subdivision of the digestive tract. The midgut is the portion of the embryo from which most of the intestines develop. After it bends around the superior mesenteric artery, it is often referred to as the \"midgut loop\". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon." [UBERON:0001045, XAO:curators] +xref: UBERON:0001045 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000092 ! archenteron +relationship: develops_from XAO:0004512 ! midgut primordium +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000104 +name: hindgut +def: "Posterior subdivision of the digestive tract. The posterior part of the alimentary canal, including the large intestine and cloaca." [UBERON:0001046, XAO:curators] +xref: UBERON:0001046 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000092 ! archenteron +relationship: develops_from XAO:0004511 ! hindgut primordium +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000105 +name: pharyngeal cavity +def: "The space enclosed by the walls of the pharynx." [BTO:0002097] +xref: UBERON:0001731 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000232 ! foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000106 +name: post-anal gut +def: "Tissue that is a temporary extension of the embryonic gut caudal to the cloaca." [http://medical-dictionary.thefreedictionary.com/gut] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000092 ! archenteron +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000107 +name: tail bud +def: "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25." [http://dictionary.reference.com/medical/tail+bud, ISBN:0815318960] +subset: frequent_anatomy_items +synonym: "tailbud" EXACT [] +xref: UBERON:0002533 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000001 ! ectoderm +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000087 ! tail region +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000108 +name: chordoneural hinge +def: "The anterior limit of the neurenteric canal, which connects the post-anal gut with the central canal of the spinal chord. It is formed from a population of cells derived from the dorsal lip of the late gastrula, and has been shown to be important in tail development." [ISBN:0762302852, PMID:11404094, PMID:7916680] +synonym: "chordo neural hinge" EXACT [] +synonym: "CNH" EXACT [] +xref: UBERON:0007097 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000107 ! tail bud +relationship: part_of XAO:0003204 ! neural tube +relationship: part_of XAO:0004057 ! tail tip +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000109 +name: posterior wall of neurenteric canal +def: "Structure formed by the ventral movement of the proctodeum anlage, which results in the shifting of the circumblastoral collar lateral walls to the posterior end of the embryo." [PMID:7916680] +synonym: "posterior wall of NEC" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000043 ! NF stage 27 +relationship: part_of XAO:0005245 ! neurenteric canal +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000110 +name: glomeral mesenchyme +def: "Portion of tissue that consists of the precursors of the pronephric glomus or glomerulus; derived from the medial portion of the pronephric intermediate mesoderm." [ISBN:0815318960] +synonym: "corpuscle" RELATED [] +synonym: "glomerulus" RELATED [] +xref: UBERON:0007128 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0000111 +name: germ cell +def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [XAO:curators] +synonym: "germ cells" EXACT PLURAL [] +synonym: "germ line cell" RELATED [] +synonym: "germ line cells" RELATED PLURAL [] +xref: CL:0000586 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000113 +name: embryo +def: "Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems." [BTO:0000379] +subset: frequent_anatomy_items +xref: UBERON:0000922 +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: develops_from XAO:0000035 ! zygote +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000114 +name: artery +def: "Any of the tubular branching vessels that carry blood from the heart through the body." [http://www.merriam-webster.com/medlineplus/artery] +xref: UBERON:0001637 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000115 +name: vein +def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [http://www.merriam-webster.com/medlineplus/vein] +xref: UBERON:0001638 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000116 +name: capillary +def: "Any of the smallest blood vessels connecting arterioles with venules." [http://www.merriam-webster.com/medlineplus/capillary] +xref: UBERON:0001982 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000117 +name: respiratory system +def: "Anatomical system that has as its parts the organs involved in breathing in respiration (breathing)." [http://dictionary.reference.com/medical/respiratory+apparatus] +xref: UBERON:0001004 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000118 +name: trachea +def: "An elongated tube that carries air to and from the lungs." [AAO:0010140] +xref: UBERON:0003126 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000117 ! respiratory system +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000119 +name: lung +def: "Either of two organs that allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air." [AAO:0010567] +xref: UBERON:0002048 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0005140 ! lung bud +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000117 ! respiratory system +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000120 +name: external gill +def: "The primary respiration organ in some species of tadpoles, whose function is the extraction of oxygen from water and the excretion of carbon dioxide. The microscopic structure of a gill is such that it presents a very large surface area to the external environment. Gills usually consist of thin filaments of tissue, branches, or slender tufted processes which have a highly folded surface to increase surface area. A high surface area is crucial for effective gas exchange." [XAO:curators] +synonym: "gill" BROAD [] +xref: UBERON:0008891 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000448 ! gill primordium +relationship: end_stage XAO:1000065 ! NF stage 53 +relationship: part_of XAO:0000117 ! respiratory system +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0000121 +name: bronchus +def: "A passage of airway in the respiratory tract that conducts air into the lungs." [XAO:curators] +synonym: "bronchial tube" EXACT [] +xref: UBERON:0002185 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000117 ! respiratory system +relationship: start_stage XAO:1000062 ! NF stage 50 + +[Term] +id: XAO:0000122 +name: hematological system +def: "Anatomical system that consists of the blood and blood forming tissues." [http://dictionary.reference.com/medical/hematologic] +synonym: "haematological system" EXACT [] +synonym: "haematopoietic system" EXACT [] +synonym: "hematopoietic system" RELATED [] +xref: UBERON:0002390 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000123 +name: bone marrow +def: "Flexible tissue found in the hollow interior of bones. In adults, marrow in large bones produces new blood cells." [UBERON:0002371] +xref: UBERON:0002371 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000010 ! juvenile frog stage + +[Term] +id: XAO:0000124 +name: blood +def: "The fluid that circulates in the heart, arteries, capillaries, and veins carrying nourishment and oxygen to and bringing away waste products from all parts of the animal." [http://www.merriam-webster.com/medlineplus/blood] +xref: UBERON:0000178 +is_a: XAO:0004001 ! portion of organism substance +relationship: develops_from XAO:0004144 ! anterior ventral blood island +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000125 +name: alimentary system +def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [http://www.merriam-webster.com/medlineplus/alimentary+system] +synonym: "digestive system" RELATED [] +synonym: "gut" RELATED [] +xref: UBERON:0001007 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000126 +name: oral cavity +def: "The cavity of the mouth, bounded by the jaw bones and associated structures." [VHOG:0000188, XAO:EJS] +xref: UBERON:0000167 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: part_of XAO:0003029 ! mouth +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000127 +name: esophagus +def: "Tube that connects the pharynx to the stomach. At NF stage 57 it is a straight tube, round in cross section, and starting from the pharynx runs backward along the dorsal side of the abdominal cavity. Its lining consists of a columnar glandular epithelium with mucus secreting cells. It is thrown into longitudinal folds." [http://dictionary.reference.com/medical/esophagus, ISBN:0815318960] +synonym: "oesophagus" EXACT [] +xref: UBERON:0001043 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000128 +name: stomach +def: "Internal organ that is the dilated portion of the alimentary tract situated between the esophagus and the beginning of the duodenum. It produces gastric juices involved in the breakdown of food." [http://dictionary.reference.com/medical/stomach] +xref: UBERON:0000945 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0004513 ! foregut endoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000129 +name: intestine +def: "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter." [AAO:0000246] +xref: UBERON:0000160 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000130 +name: small intestine +def: "A part of the alimentary system and principal organ of digestion, comprising the duodenum and ileum and characterized by longitudinal folds. In the tadpole it is a long simple tube with a single layer of cuboidal epithelial cells." [PMID:15738398] +xref: UBERON:0002108 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000103 ! midgut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000129 ! intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000131 +name: large intestine +def: "A short, wide tube that is part of the alimentary system and comprises the colon and rectum and empties into the cloaca. It lacks longitudinal folds characteristic of the small intestine. It absorbs water and salts from the gut lumen." [PMID:21471667] +xref: UBERON:0000059 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000104 ! hindgut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000129 ! intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000132 +name: liver and biliary system +def: "Anatomical system comprising the liver, gall bladder, and associated ducts." [XAO:EJS] +xref: UBERON:0002423 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000133 +name: liver +def: "Organ that secretes bile and participates in formation of certain blood proteins. The liver is the largest internal organ, primarily consisting of hepatocytes, and has a wider variety of functions than any other organs in the body. The hepatocyte is a polarized epithelial cell that exhibits both endocrine and exocrine properties. The biliary epithelial cells (cholangiocytes), sinusoidal endothelial cells, hepatic stellate cells (Ito cells), Kupffer cells, and pit cells (liver-specific natural killer cells) represent the majority of non-hepatocyte cell types in the liver. During embryogenesis, the liver is generated in the ventral foregut endoderm." [AAO:0010111, PMID:17474120] +xref: UBERON:0002107 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003164 ! solid compound organ +relationship: develops_from XAO:0003266 ! liver primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000132 ! liver and biliary system +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000134 +name: bile duct +def: "Duct that carries bile from the liver to the small intestine." [XAO:EJS, ZFA:0001100] +synonym: "hepatic duct" RELATED [] +xref: UBERON:0002394 +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000132 ! liver and biliary system +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000135 +name: gall bladder +def: "A small organ of the alimentary system that aids mainly in fat digestion, and concentrates bile that is produced by the liver." [XAO:EJS, ZFA:0000208] +synonym: "gallbladder" EXACT [] +xref: UBERON:0002110 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003041 ! compound organ +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: develops_from XAO:0004205 ! gall bladder primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000132 ! liver and biliary system +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000136 +name: pancreas +def: "Internal gland organ with distinct tissues with different endocrine and exocrine functions. Its rudiment has three parts, one dorsal and two ventral primordia. The ventral can be first detected at NF stage 37/38. The dorsal is clearly segregated from the duodenal wall by NF stage 39. At NF stage 40 the right and left primordia have fused just above the gastro-duodenal vein. At NF stage 42 blood vessels penetrate into the crevices between the pancreatic acini making them more conspicuous." [ISBN:0815318960, ISBN:0881679860] +xref: UBERON:0001264 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003041 ! compound organ +relationship: develops_from XAO:0000467 ! dorsal pancreatic bud +relationship: develops_from XAO:0001103 ! ventral pancreatic bud +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0000137 +name: exocrine pancreas +def: "Pancreatic tissue composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion." [XAO:EJS, ZFA:0001249] +xref: UBERON:0000017 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000136 ! pancreas +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0000138 +name: mesentery +def: "A double layer of tissue composed of peritoneum that attaches the visceral organs to the body wall." [XAO:EJS, ZFA:0005129] +synonym: "mesenterium" RELATED [] +xref: UBERON:0007826 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000139 +name: peritoneum +def: "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium." [AAO:0010814] +xref: UBERON:0002358 +is_a: XAO:0004466 ! serous membrane +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000140 +name: urogenital system +def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [http://www.merriam-webster.com/medlineplus/genitourinary+tract] +xref: UBERON:0004122 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000141 +name: mesonephric kidney +def: "A visceral organ which provides osmoregulation and waste excretion for tadpoles through adult stages in Xenopus. The mesonephros starts to develop at NF stage 39, then during feeding stage tadpoles through metamorphosis replaces the embryonic pronephros as it degenerates." [XAO:curators] +synonym: "adult kidney" RELATED [] +synonym: "mesonephros" RELATED [] +synonym: "opisthonephros" RELATED [] +synonym: "urniere" RELATED [] +synonym: "Wolffian body" RELATED [] +xref: UBERON:0000080 +is_a: XAO:0005244 ! adult kidney +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0000142 +name: genital system +def: "Anatomical system that has as its parts the organs concerned with reproduction." [http://www.merriam-webster.com/medlineplus/genitourinary+tract] +synonym: "reproductive system" RELATED [] +xref: UBERON:0000990 +is_a: XAO:0003002 ! anatomical system +relationship: develops_from XAO:0000018 ! genital ridge +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000143 +name: urinary system +def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine." [http://www.merriam-webster.com/medlineplus/genitourinary+tract] +xref: UBERON:0001008 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000144 +name: ureter +def: "Anatomical structure consisting of a long narrow duct that carries urine from the kidney to the urinary bladder." [AAO:0010254] +xref: UBERON:0000056 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000143 ! urinary system +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000146 +name: glomerulus +def: "A tuft of capillaries found in a Bowman's capsule in which waste products are filtered from the blood and urine formation is initiated." [AAO:0010388, XAO:curators] +synonym: "renal corpuscle" RELATED [] +xref: UBERON:0005325 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000292 ! mesonephric nephron +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000147 +name: obsolete glomerus +is_obsolete: true + +[Term] +id: XAO:0000148 +name: mesonephric tubule +def: "Any of the excretory units of the mesonephros, which connect to the mesonephric collecting duct." [http://www.bionalogy.com/urinary_system.htm] +synonym: "renal tubule" RELATED [] +xref: UBERON:0000083 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000292 ! mesonephric nephron +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000149 +name: obsolete renal proximal convoluted tubule +is_obsolete: true +consider: XAO:0000331 + +[Term] +id: XAO:0000150 +name: obsolete loop of Henle +is_obsolete: true + +[Term] +id: XAO:0000151 +name: mesonephric collecting duct +def: "Duct that connects to the mesonephric nephrons and collects filtrate." [http://en.wikipedia.org/wiki/Collecting_duct_system] +synonym: "collecting duct" RELATED [] +xref: UBERON:0005319 +is_a: XAO:0004000 ! duct +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000148 ! mesonephric tubule +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000152 +name: obsolete renal distal convoluted tubule +is_obsolete: true +consider: XAO:0000334 + +[Term] +id: XAO:0000153 +name: urethra +def: "Anatomical structure consisting of a tube carries urine from the urinary bladder to the outside of the body." [XAO:EJS] +xref: UBERON:0000057 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000143 ! urinary system +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000154 +name: bladder +def: "The organ that collects urine excreted by the kidneys before disposal by urination." [XAO:curators] +synonym: "urinary bladder" EXACT [] +xref: UBERON:0001255 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000143 ! urinary system +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0000155 +name: male genitalia +def: "Anatomical system comprising the organs of the male reproductive system." [http://www.merriam-webster.com/medlineplus/genitalia] +synonym: "male genitals" RELATED PLURAL [] +xref: UBERON:0000079 +is_a: XAO:0000142 ! genital system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003006 ! male organism +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000156 +name: female genitalia +def: "Anatomical system comprising the organs of the female reproductive system." [http://www.merriam-webster.com/medlineplus/genitalia] +synonym: "female genitals" RELATED PLURAL [] +xref: UBERON:0000474 +is_a: XAO:0000142 ! genital system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003005 ! female organism +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000157 +name: testis +def: "Reproductive organ that produces and releases sperm." [XAO:curators] +synonym: "testes" RELATED PLURAL [] +xref: UBERON:0000473 +is_a: XAO:0003146 ! gonad +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000155 ! male genitalia +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000158 +name: endocrine system +def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [http://www.merriam-webster.com/medlineplus/endocrine+system] +xref: UBERON:0000949 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0000159 +name: islets of Langerhans +def: "Structure that is made up of islet cells that produce insulin, glucagon, and somatostatin." [UBERON:0000016] +synonym: "endocrine pancreas" RELATED [] +xref: UBERON:0000006 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0001103 ! ventral pancreatic bud +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000136 ! pancreas +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000160 +name: pineal gland +def: "An unpaired glandular organ subdivision attached on the midline near the posterior and habenular commissures of the epithalamus." [UBERON:0001905] +synonym: "epiphysis" RELATED [] +synonym: "pineal organ" RELATED [] +xref: UBERON:0001905 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: part_of XAO:0000158 ! endocrine system +relationship: part_of XAO:0003198 ! visual system +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000162 +name: thyroid +def: "A two-lobed endocrine gland, located next to the trachea, and producing various hormones, such as triiodothyronine and calcitonin." [UBERON:0002046] +synonym: "thyroid gland" EXACT [] +xref: UBERON:0002046 +is_a: XAO:0003041 ! compound organ +relationship: develops_from XAO:0000444 ! thyroid primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000163 +name: thymus +def: "Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop." [http://www.merriam-webster.com/medlineplus/thymus] +xref: UBERON:0002370 +is_a: XAO:0003041 ! compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000164 +name: adrenal gland +def: "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine." [UBERON:0002369] +xref: UBERON:0002369 +is_a: XAO:0003164 ! solid compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0000165 +name: adrenal cortex +def: "Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. The perimeter region of the adrenal gland, the site of steroid synthesis." [PMID:14061885, UBERON:0001235] +synonym: "interrenal tissue" RELATED [] +xref: UBERON:0001235 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000164 ! adrenal gland +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0000166 +name: adrenal medulla +def: "Part of the adrenal gland, located at the center of the gland and surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine, norepinephrine, and a small amount of dopamine in response to stimulation by sympathetic preganglionic neurons. Composed mainly of hormone-producing chromaffin cells, it is the principal site of the conversion of the amino acid tyrosine into the catecholamines adrenaline (epinephrine), noradrenaline (norepinephrine), and dopamine." [UBERON:0001236] +synonym: "chromaffin cells" RELATED [] +xref: UBERON:0001236 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000319 ! trunk neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000164 ! adrenal gland +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000167 +name: parathyroid +alt_id: XAO:0000450 +def: "An organ specialized for secretion of parathyroid hormone. It controls the amount of calcium in the blood and within the bones." [UBERON:0001132] +synonym: "epithelial body" RELATED [] +synonym: "parathyroid gland" EXACT [] +xref: UBERON:0001132 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000247 ! visceral pouch 2 +relationship: develops_from XAO:0000447 ! branchial arch 1 +relationship: develops_from XAO:0000452 ! ultimobranchial body +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000168 +name: musculoskeletal system +def: "Anatomical system that provides locomotion and physical support to the organism." [XAO:curators] +xref: UBERON:0002204 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000169 +name: bone tissue +def: "The hard form of connective tissue that constitutes the majority of the skeleton." [BTO:0000140] +synonym: "bone" RELATED [] +xref: UBERON:0002481 +is_a: XAO:0004038 ! skeletal tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004276 ! bone element +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000170 +name: cartilage tissue +def: "A type of dense connective tissue that is composed of specialized cells, chondrocytes, that produce a large amount of extracellular matrix." [http://en.wikipedia.org/wiki/Cartilage] +synonym: "cartilage" RELATED [] +xref: UBERON:0002418 +is_a: XAO:0004038 ! skeletal tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004026 ! endoskeleton +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000171 +name: joint +def: "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue." [XAO:EJS, ZFA:0001596] +synonym: "articulation" EXACT [] +xref: UBERON:0000982 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004274 ! articular system +relationship: part_of XAO:0004313 ! joint region +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000172 +name: muscle +def: "A body tissue consisting of long cells that contract when stimulated and produce motion." [BTO:0000887] +subset: frequent_anatomy_items +xref: UBERON:0001630 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004042 ! muscular system +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000173 +name: tendon +alt_id: XAO:0000400 +def: "A fibrous, strong, connective tissue that connects muscle to bone." [http://dictionary.reference.com/medical/tendon] +xref: UBERON:0000043 +is_a: XAO:0004030 ! dense regular connective tissue +relationship: develops_from XAO:0000399 ! tendon fibroblast +relationship: develops_from XAO:0005325 ! syndetome +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000174 +name: skeletal muscle +def: "A type of muscle used to create movement, by applying force to bones and joints. Usually attached to bones by tendons." [http://en.wikipedia.org/wiki/Skeletal_muscle] +xref: UBERON:0001134 +is_a: XAO:0000172 ! muscle +relationship: develops_from XAO:0000314 ! trunk somite +relationship: develops_from XAO:0000315 ! myotome +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000175 +name: smooth muscle +def: "Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers. Found within the walls of blood vessels, the alimentary tract, bladder, and reproductive tract." [AAO:0010244, XAO:curators] +synonym: "visceral muscle" RELATED [] +xref: UBERON:0001135 +is_a: XAO:0000172 ! muscle +relationship: develops_from XAO:0000311 ! lateral plate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000176 +name: dermal system +def: "Anatomical system that consists of the skin and its appendages." [http://dictionary.reference.com/medical/dermal+system] +xref: UBERON:0002416 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000177 +name: nervous system +def: "Anatomical system that has as its parts the brain and spinal cord, nerves, ganglia, and parts of the receptor organs and that receives and interprets stimuli and transmits impulses to the effector organs." [AAO:0000324] +subset: frequent_anatomy_items +xref: UBERON:0001016 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000178 +name: peripheral nervous system +def: "One of the two major divisions of the nervous system. Its nerves connect the central nervous system with sensory organs, other organs, muscles, blood vessels and glands." [http://dictionary.reference.com/medical/peripheral+nervous+system] +synonym: "PNS" EXACT [] +xref: UBERON:0000010 +is_a: XAO:0000177 ! nervous system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000179 +name: eye +def: "The organ of sight (visual apparatus), almost spherical in shape. At the end of development (NF stage 66) the eyes bulge out of their orbital capsules near the lateral edge of the dorsal side of the head." [ISBN:0815318960, XAO:curators] +subset: frequent_anatomy_items +synonym: "eyes" RELATED PLURAL [] +xref: UBERON:0000019 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000228 ! optic vesicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000215 ! central nervous system +relationship: part_of XAO:0003024 ! head +relationship: part_of XAO:0003198 ! visual system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000180 +name: cornea +def: "The transparent front part of the eye that, together with the lens, refracts light." [http://en.wikipedia.org/wiki/Cornea] +xref: UBERON:0000964 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0004091 ! non-neural ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000181 +name: globe +def: "A general term for the whole eye, or eye ball, of an organism." [AAO:0010346] +synonym: "eye ball" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000182 +name: conjunctiva +def: "A clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera and lines the inside of the eyelids. It is made of epithelial tissue." [UBERON:0001811] +synonym: "conjunctivae" EXACT PLURAL [] +synonym: "conjunctivas" EXACT PLURAL [] +xref: UBERON:0001811 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0000183 +name: sclera +def: "The opaque, fibrous, protective, outer layer of the eye containing collagen and elastic fiber." [UBERON:0001773] +xref: UBERON:0001773 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0000185 +name: iris +def: "A membrane in the eye, responsible for controlling the amount of light reaching the retina." [UBERON:0001769] +xref: UBERON:0001769 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000228 ! optic vesicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: part_of XAO:0004529 ! uveal tract +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000186 +name: ciliary body +def: "Circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [UBERON:0001775] +xref: UBERON:0001775 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: part_of XAO:0004529 ! uveal tract +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0000187 +name: dorsolateral placode region +def: "Lateral neurogenic placode region positioned dorsally to the epibranchial placodes, and that includes the lateral line placodes, the otic placode and the trigeminal placode." [ISBN:0878933840, ZFA:0001310] +xref: UBERON:0003067 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000188 +name: optic nerve +def: "Cranial nerve that is continuous with the layer of nerve cells on the inner surface of the eye. It exits the neurocranium via the large optic foramen and is covered by a fibrous connective tissue sheath. It transmits visual information from the retina to the brain." [ISBN:080184780X, UBERON:0000941] +synonym: "cranial nerve II" EXACT [] +synonym: "ON" EXACT [] +synonym: "opticus" EXACT [] +xref: UBERON:0000941 +is_a: XAO:0000429 ! cranial nerve +relationship: develops_from XAO:0000475 ! optic stalk +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000189 +name: auditory apparatus +def: "The combination of structures that form the ear and function to transmit vibrations and permit hearing." [ISBN:0070179778] +synonym: "ear" BROAD [] +xref: UBERON:0001690 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000006 ! otic vesicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003195 ! vestibuloauditory system +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000190 +name: tympanic disk +alt_id: XAO:0000212 +def: "A flattened, roughly circular cartilage derived from the extrastapes. This thin membrane or integument is stretched over the cartilaginous tympanic annulus in a drum-like manner, and forms the outer ear, receiving airborne vibrations and functioning in hearing." [ISBN:0070179778, PMID:20953303] +synonym: "external ear" RELATED [] +synonym: "tympanic disc" EXACT [] +synonym: "tympanic membrane" RELATED [] +synonym: "tympanum" RELATED [] +xref: UBERON:0001691 +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0005141 ! pars externa of the stapes +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000189 ! auditory apparatus +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000191 +name: middle ear +def: "The air-filled cavity within the skull that lies between the outer ear and the inner ear." [UBERON:0001756] +synonym: "tympanic cavity" EXACT [] +xref: UBERON:0001756 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000189 ! auditory apparatus +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000192 +name: inner ear +alt_id: XAO:0000194 +def: "Labyrinthine anatomical cluster that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation." [PMID:16217737] +synonym: "membranous labyrinth" EXACT [] +xref: UBERON:0001846 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000189 ! auditory apparatus +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000193 +name: osseous labyrinth +def: "Structure consisting of the vestibule, lagena, and semicircular canal, cavities that are hollowed out of the substance of the bone, and lined by periosteum. They contain a clear fluid, the perilymph, in which the membranous labyrinth is situated." [http://en.wikipedia.org/wiki/Bony_labyrinth] +synonym: "bony labyrinth" RELATED [] +xref: UBERON:0001839 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000195 +name: utricle +def: "Inner ear structure into which the semicircular ducts find their outlet. Along with the saccule, it is part of the balancing apparatus (membranous labyrinth) located within the vestibule of the osseous labyrinth." [http://en.wikipedia.org/wiki/Utricle_(ear)] +synonym: "utricular otolith" RELATED [] +xref: UBERON:0001853 +is_a: XAO:0000214 ! auditory ossicle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000196 +name: sacculus +def: "A major structure of the inner ear, ventral to the utriculus. Two small pouches extend from it: the papilla basilaris, and the papilla amphibiorum. The sacculus functions in the detection of sound." [ISBN:0070179778] +synonym: "saccule" RELATED [] +xref: UBERON:0001854 +is_a: XAO:0000214 ! auditory ossicle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000197 +name: lagena +def: "A vestibular structure of the inner ear consisting of a ventral diverticulum off of the sacculus." [ISBN:1402073755] +synonym: "cochlea" RELATED [] +xref: UBERON:0001844 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000193 ! osseous labyrinth +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000198 +name: semicircular canal +def: "Any of the three fluid-filled ducts that loop from the utriculus in the inner ear, and help detect movement and maintain balance." [ISBN:0070179778] +synonym: "semicircular canals" RELATED PLURAL [] +synonym: "semicircular ducts" RELATED PLURAL [] +xref: UBERON:0001840 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000193 ! osseous labyrinth +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000199 +name: vestibule +def: "The small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear." [UBERON:0005236] +xref: UBERON:0005236 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000193 ! osseous labyrinth +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000200 +name: animal blastomere +def: "Pigmented, smaller blastomere of the animal (upper) hemisphere of the cleaving embryo." [ISBN:0471209627] +synonym: "animal hemisphere blastomere" EXACT [] +synonym: "micromere" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0000202 ! animal hemisphere +relationship: end_stage XAO:1000017 ! NF stage 7 +relationship: part_of XAO:0000202 ! animal hemisphere +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) + +[Term] +id: XAO:0000201 +name: obsolete olfactory apparatus +is_obsolete: true +consider: XAO:0000273 + +[Term] +id: XAO:0000202 +name: animal hemisphere +def: "Anatomical region that is pigmented (dark brown) and tends to have the uppermost orientation, as it contains the blastocoel and cells that contain only small amounts of yolk. The Xenopus egg is divided into two roughly equal halves: the animal and vegetal hemispheres." [XAO:curator] +xref: UBERON:0012284 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000203 +name: obsolete archencephalic region +is_obsolete: true + +[Term] +id: XAO:0000204 +name: peripheral nerve +def: "Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors." [NCIt:Peripheral_Nerve] +xref: UBERON:0002003 +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005199 ! peripheral ganglion +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000205 +name: axial mesoderm +def: "A type of mesoderm that lies along the central axis, under the neural tube, and gives rise to the notochord." [XAO:curators] +synonym: "chordamesoderm" RELATED [] +synonym: "chordomesoderm" RELATED [] +xref: UBERON:0003068 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000050 ! mesoderm +relationship: develops_from XAO:0004406 ! presumptive axial mesoderm +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0000206 +name: blastocoel anlage +def: "The first appearance of the anatomical space that will become the blastocoel." [XAO:curators] +is_a: XAO:0003043 ! primordium +relationship: end_stage XAO:1000018 ! NF stage 8 +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0000207 +name: blastocoel roof +def: "The dorsal surface of the blastocoel, the cavity of the blastula." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000294 ! blastocoel +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0000208 +name: blastopore +def: "The opening of the archenteron to the exterior, marking the point of origin of the archenteron and the caudal end of the embryo." [ISBN:0023771100] +xref: UBERON:0000100 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000090 ! endoderm +relationship: develops_from XAO:0000281 ! vegetal yolk mass +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0000068 ! marginal zone +relationship: part_of XAO:0000281 ! vegetal yolk mass +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000209 +name: ganglion +def: "A cluster of nervous tissue principally composed of neuronal cell bodies external to the central nervous system (CNS)." [UBERON:0000045] +synonym: "ganglia" RELATED PLURAL [] +xref: UBERON:0000045 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0000210 +name: spinal ganglion +def: "Type of ganglion that is a condensation of sensory neurons on the dorsal root of each spinal nerve. There is one pair of spinal ganglia per myotome, with the spinal ganglia of the trunk region larger and more distinct from each other than those of the tail region." [PMID:17521450, XAO:curators] +synonym: "dorsal root ganglion" RELATED [] +synonym: "spinal ganglia" RELATED PLURAL [] +xref: UBERON:0000044 +is_a: XAO:0000209 ! ganglion +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000211 +name: sympathetic chain +def: "Either of the pair of ganglionated longitudinal cords of the sympathetic nervous system of which one is situated on each side of the spinal column." [http://www.merriam-webster.com/medical/sympathetic%20chain] +synonym: "sympathetic trunk" EXACT [] +xref: UBERON:0000407 +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000213 +name: auditory tube +def: "The narrow tube connecting the middle ear with the pharynx, through which air flows to equalize pressure on either side of the tympanic membrane." [ISBN:0070179778] +synonym: "eustachian tube" EXACT [] +synonym: "pharyngotympanic tube" EXACT [] +xref: UBERON:0002393 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000189 ! auditory apparatus +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000214 +name: auditory ossicle +def: "Any of the three tiny bones of the inner ear (columella or stapes, the sacculus and the utriculus) suspended in the otic capsule." [ISBN:0070179778] +xref: UBERON:0001686 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000189 ! auditory apparatus +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000215 +name: central nervous system +def: "The part of the nervous system that consists of the brain and spinal cord, to which sensory impulses are transmitted and from which motor impulses pass out, and that supervises and coordinates the activity of the entire nervous system." [http://www.merriam-webster.com/medlineplus/central+nervous+system] +synonym: "CNS" EXACT [] +xref: UBERON:0001017 +is_a: XAO:0000177 ! nervous system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000216 +name: obsolete cortex +is_obsolete: true +consider: XAO:0004467 +consider: XAO:0004468 + +[Term] +id: XAO:0000217 +name: dermis +def: "A layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, composed of two layers, the papillary and reticular dermis." [UBERON:0002067] +xref: UBERON:0002067 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000220 ! dermatome +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000218 +name: appendage +def: "An internal or external body part or prolongation that projects from, and is attached to, an organ or the main body of an organism." [XAO:curators] +synonym: "appendages" RELATED PLURAL [] +xref: UBERON:0000026 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000219 +name: obsolete superficial (epithelial) layer +is_obsolete: true + +[Term] +id: XAO:0000220 +name: dermatome +def: "Somitic compartment that is a precursor of dermis, the cells of which become arranged in a single layer that blankets the myotome, possibly continuously (unsegmented) across somites." [PMID:17313522] +xref: UBERON:0004016 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000396 ! head somite 1 +relationship: develops_from XAO:0000403 ! head somite 2 +relationship: develops_from XAO:0000404 ! head somite 3 +relationship: develops_from XAO:0000405 ! head somite 4 +relationship: develops_from XAO:0000406 ! trunk somite 1 +relationship: develops_from XAO:0000407 ! trunk somite 2 +relationship: develops_from XAO:0000408 ! trunk somite 3 +relationship: develops_from XAO:0000409 ! trunk somite 4 +relationship: develops_from XAO:0000410 ! trunk somite 5 +relationship: develops_from XAO:0000411 ! trunk somite 6 +relationship: develops_from XAO:0000412 ! trunk somite 7 +relationship: develops_from XAO:0000416 ! trunk somite 8 +relationship: develops_from XAO:0000417 ! trunk somite 9 +relationship: develops_from XAO:0000418 ! trunk somite 10 +relationship: develops_from XAO:0000419 ! trunk somite 11 +relationship: develops_from XAO:0000420 ! trunk somite 12 +relationship: develops_from XAO:0000421 ! trunk somite 13 +relationship: develops_from XAO:0000422 ! tail somite 14 +relationship: develops_from XAO:0000423 ! tail somite 15 +relationship: develops_from XAO:0000424 ! tail somite 16 +relationship: develops_from XAO:0000425 ! tail somite 17 +relationship: develops_from XAO:0004528 ! tail somite 18 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0005080 ! dermomyotome +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000221 +name: obsolete deuterencephalic region +is_obsolete: true + +[Term] +id: XAO:0000222 +name: obsolete ear placode +is_obsolete: true +replaced_by: XAO:0000223 + +[Term] +id: XAO:0000223 +name: otic placode +def: "Invagination of thickened epithelium near the hindbrain that gives rise to a spherically shaped ear vesicle, including precursors of the sensory epithelia of the inner ear and neurons of cranial nerve VIII." [PMID:16217737] +synonym: "auditory placode" RELATED [] +synonym: "ear" BROAD [] +xref: UBERON:0003069 +is_a: XAO:0004620 ! neurogenic placode +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: develops_from XAO:0004207 ! posterior placodal area +relationship: end_stage XAO:1000042 ! NF stage 26 +relationship: part_of XAO:0003195 ! vestibuloauditory system +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000224 +name: vegetal part, early involuting +def: "Vegetal portion of the marginal zone of the embryo that turns inside the embryo during involution." [http://worms.zoology.wisc.edu/frogs/glossary.html] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000074 ! involuting marginal zone +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000225 +name: trigeminal placode +def: "The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24. The trigeminal placode gives rise to the sensory neurons of the ophthalmic and maxillomandibular lobes of cranial nerve V." [PMID:21452441, UBERON:0003070] +xref: UBERON:0003070 +is_a: XAO:0004620 ! neurogenic placode +relationship: develops_from XAO:0000187 ! dorsolateral placode region +relationship: develops_from XAO:0004206 ! anterior placodal area +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000226 +name: equatorial belt +def: "Equatorial zone of the zygote with which the plane of first cleavage aligns." [XAO:EJS] +is_a: XAO:0003040 ! tissue +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: part_of XAO:0000035 ! zygote +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000227 +name: eye primordium +def: "First trace of the future visual apparatus. The eye primordia forming antero-lateral evaginations of the closing neural tube are originally massive formations into which only a slit-shaped extension of the neural groove penetrates at NF stage 18. At NF stage 19 they clearly segregate from the anterior portion of the neural tube." [ISBN:0815318960] +synonym: "eye" BROAD [] +synonym: "eye anlage" RELATED [] +xref: UBERON:0003071 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0004090 ! optic field +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0003198 ! visual system +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0000228 +name: optic vesicle +def: "The evagination of neurectoderm, which has pinched off from the anterior neural keel, that precedes formation of the optic cup." [XAO:curators] +synonym: "eye" BROAD [] +synonym: "eye vesicle" RELATED [] +synonym: "optic cup" RELATED [] +xref: UBERON:0004128 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000227 ! eye primordium +relationship: develops_from XAO:0005316 ! periocular mesenchyme +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0003198 ! visual system +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000229 +name: fasciculated network of fibrils +def: "Randomly dispersed fibrils organized into criss-crossing fascicles or bundles in the coelomic envelope of oocytes." [PMID:2909400] +synonym: "coelomic envelope" BROAD [] +is_a: XAO:0003040 ! tissue +is_a: XAO:0004005 ! extraembryonic structure +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0000230 +name: follicle cell +def: "Cell type that forms a layer within an ovarian follicle that surrounds the oocyte." [http://dictionary.reference.com/medical/follicle+cell] +xref: CL:0000477 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000258 ! ovary +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000231 +name: follicle layer +def: "A monolayer of follicle cells surrounding the developing oocyte and forming adhesive contacts with the surrounding follicular epithelium." [PMID:619165] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000258 ! ovary +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000232 +name: foregut +def: "The anterior part of the alimentary system, from the mouth and esophagus to the duodenum at the entrance of the bile duct. Structures of the foregut are: esophagus, stomach, duodenum, liver, gall bladder, and pancreas. The spleen is located in the foregut region, but is not a gut organ." [UBERON:0001041, XAO:curators] +xref: UBERON:0001041 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000092 ! archenteron +relationship: develops_from XAO:0004513 ! foregut endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000233 +name: germ plasm +def: "A zone found in the cytoplasm of the egg cells that contains determinants that will give rise to the primordial germ cells. As the zygote undergoes mitotic divisions the germ plasm is ultimately restricted to a few cells of the embryo." [XAO:curators] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000280 ! vegetal hemisphere +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0000234 +name: germinal vesicle +def: "The nucleus of the oocyte, it is enclosed in a nuclear envelope and contains neucleoplasm, in which the chromosomes and extranucleoli are embedded. It breaks down as the oocyte matures, being no longer visible by the first meiotic metaphase." [XAO:curators] +synonym: "GV" EXACT [] +is_a: XAO:0005038 ! nucleus +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000088 ! oocyte stage VI + +[Term] +id: XAO:0000235 +name: cardiac mesoderm +def: "Two migratory heart primordia that move ventrally during the course of neurulation, and whose fusion begins at the ventral midline at NF stage 16." [XAO:curators] +synonym: "heart" BROAD [] +xref: UBERON:0007005 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0005062 ! proepicardium +relationship: end_stage XAO:1000039 ! NF stage 23 +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000236 +name: duodenum +def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960] +xref: UBERON:0002114 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000130 ! small intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000237 +name: ileum +def: "The final section of the small intestine." [UBERON:0002116] +xref: UBERON:0002116 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000130 ! small intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000238 +name: rectum +def: "The terminal portion of the large intestine." [VHOG:0001751] +xref: UBERON:0001052 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000131 ! large intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000239 +name: hepato-pancreatic duct +def: "The pancreatic duct and common bile duct together, which enter the descending duodenum." [XAO:curators] +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000132 ! liver and biliary system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000240 +name: lens placode +def: "A thickened portion of ectoderm that serves as the precursor to the lens." [UBERON:0003073] +synonym: "lens primordium" RELATED [] +xref: UBERON:0003073 +is_a: XAO:0005283 ! non-neurogenic ectodermal placode +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0004206 ! anterior placodal area +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000241 +name: posterior cardinal vein +def: "Vein that returns blood from the trunk and drains into the duct of Cuvier via the pronephric sinus." [PMID:12606281] +synonym: "PCV" EXACT [] +xref: UBERON:0002065 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000052 ! cardinal vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000242 +name: mesonephric duct +def: "Duct that drains the mesonephros and connects it to the ureter." [XAO:EJS] +synonym: "Wolffian duct" RELATED [] +xref: UBERON:0003074 +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000063 ! pronephric duct +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000141 ! mesonephric kidney +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000243 +name: colon +def: "The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body." [UBERON:0001155] +synonym: "hindgut" BROAD [] +synonym: "posterior intestine" RELATED [] +xref: UBERON:0001155 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000131 ! large intestine +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000244 +name: cloaca +def: "The posterior opening that serves as the common opening for the intestinal, reproductive, and urinary tracts, closed by the cloacal sphincter." [XAO:curators] +subset: frequent_anatomy_items +synonym: "cloacal chamber" RELATED [] +synonym: "vent" RELATED [] +xref: UBERON:0000162 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000107 ! tail bud +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000245 +name: mitochondrial cloud +def: "A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material." [GO:0032019] +synonym: "Balbiani body" EXACT [] +synonym: "MC" RELATED [] +synonym: "mitochondrial aggregate" EXACT [] +xref: GO:0032019 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000083 ! oocyte stage I +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0000246 +name: myocoelic slit +def: "Space that separates the thicker inner sheet of splanchnic mesoderm from the thinner outer somatic mesoderm." [PMID:5449482] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0000315 ! myotome +relationship: start_stage XAO:1000026 ! NF stage 16 + +[Term] +id: XAO:0000247 +name: visceral pouch 2 +def: "Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634] +synonym: "second visceral pouch" EXACT [] +xref: UBERON:0007123 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000248 +name: neural groove +def: "The median dorsal longitudinal groove in the neural plate, directly above the notochord, which appears after neural fold formation." [http://www.merriam-webster.com/medlineplus/neural+groove, XAO:curators] +synonym: "median groove" RELATED [] +synonym: "neural midline" RELATED [] +xref: UBERON:0005061 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000249 +name: neural plate +def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube. At NF stage 11.5 is the first indication of neural plate within the sensorial layer of ectoderm. It extends to near the animal pole by NF stage 12.5 and the entire plate is faintly delimited by NF stage 13." [http://dictionary.reference.com/medical/neural+plate, ISBN:0815318960] +xref: UBERON:0003075 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0000250 +name: posterior neural tube +def: "Posterior segment of the neural tube, which develops into the hindbrain and spinal cord." [XAO:EJS] +xref: UBERON:0003076 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000046 ! chordal neural plate +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000251 +name: visceral pouch 3 +def: "Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634] +synonym: "third visceral pouch" EXACT [] +xref: UBERON:0007124 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000252 +name: neurocoel +def: "An anatomical space that is surrounded by a neural tube." [UBERON:0003842] +synonym: "neural tube lumen" EXACT [] +xref: UBERON:0003842 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000253 +name: non-involuting marginal zone +def: "Animal portion of the marginal zone of the embryo that spreads in front of the animal cap but does not involute during gastrulation." [http://worms.zoology.wisc.edu/frogs/glossary.html] +synonym: "NIMZ" EXACT [] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000254 +name: visceral pouch 4 +def: "Fourth of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634] +synonym: "fourth visceral pouch" EXACT [] +xref: UBERON:0007125 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000255 +name: visceral pouch 5 +def: "Fifth of the pharyngeal (endodermal) evaginations between the visceral arches." [ISBN:0226557634] +synonym: "fifth visceral pouch" EXACT [] +xref: UBERON:0007126 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000256 +name: oocyte +def: "The developing female gamete, the differentiation of which is classified into six stages: I (pre-vitellogenic), II (early vitellogenic), III (mid-vitellogenic, formation of pigment), IV (polarization along animal-vegetal axis), V (late vitellogenic), and VI (post-vitellogenic, appearance of equatorial band)." [PMID:4109871] +xref: CL:0000023 +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0000268 ! secondary oogonium +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0000257 +name: oral evagination +def: "An outpocketing of the foregut ventral to the infundibulum and the hypophysis. The walls surrounding this cavity are composed of endoderm." [http://www.uoguelph.ca/zoology/devobio/34mmfrog/db34fg1.htm] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000232 ! foregut +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000258 +name: ovary +def: "Either of paired female reproductive organs involved in production of ova and female sex hormones." [AAO:0000371] +xref: UBERON:0000992 +is_a: XAO:0003146 ! gonad +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000156 ! female genitalia +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000259 +name: paraxial mesoderm +def: "Area of mesoderm at either side of the midline embryonic notochord that, on segmentation, forms the paired somites." [http://dictionary.reference.com/medical/paraxial+mesoderm] +xref: UBERON:0003077 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0004134 ! presumptive paraxial mesoderm +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: part_of XAO:0000050 ! mesoderm +relationship: start_stage XAO:1000024 ! NF stage 14 + +[Term] +id: XAO:0000260 +name: perivitelline space +def: "The space between the zona pellucida and the cell membrane of an oocyte or fertilized ovum." [http://en.wikipedia.org/wiki/Perivitelline_space] +is_a: XAO:0004005 ! extraembryonic structure +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: part_of XAO:0000035 ! zygote +relationship: start_stage XAO:1000092 ! mature egg stage + +[Term] +id: XAO:0000261 +name: pigment layer +def: "Outer layer of the developing optic vesicle, which contains pigmented epithelium." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0000228 ! optic vesicle +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000262 +name: polar body +def: "A small cell formed by the meiotic division of an oocyte." [CL:0002090] +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000256 ! oocyte +relationship: end_stage XAO:1000088 ! oocyte stage VI +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0000263 +name: primary oogonium +def: "A germ cell that is a primordial oocyte in a female and that develops into secondary oogonia by mitotic division." [XAO:EJS] +synonym: "primary oogonia" RELATED PLURAL [] +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0003149 ! primordial germ cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000258 ! ovary +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000264 +name: pronephric mesenchyme +def: "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30." [XAO:curators] +synonym: "pronephric anlage" RELATED [] +synonym: "pronephric bulge" RELATED [] +synonym: "pronephric primordium" RELATED [] +xref: UBERON:0005721 +is_a: XAO:0003046 ! mesenchyme +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0000265 +name: visceral pouch 6 +def: "Sixth of the pharyngeal (endodermal) evaginations between the visceral arches." [ISBN:0226557634] +synonym: "sixth visceral pouch" EXACT [] +xref: UBERON:0007127 +is_a: XAO:0000282 ! visceral pouch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000266 +name: retinal layer +def: "Inner layer of the developing optic vesicle, which contains retinal nerve cells." [XAO:EJS] +xref: UBERON:0001781 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0000228 ! optic vesicle +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000267 +name: hypophyseal primordium +def: "The hypophyseal layer that separates from the stomodeal layer of the stomodeal-hypophyseal primordium at NF stage 29 and 30." [XAO:EJS] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000268 +name: secondary oogonium +def: "A type of germ cell that results from the mitotic division of a primary oogonium." [XAO:EJS] +synonym: "secondary oogonia" RELATED PLURAL [] +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0000263 ! primary oogonium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0000269 +name: mouth primordium +def: "Anterior part of the embryonic alimentary canal that is formed as an invagination of the ectoderm and is the future mouth." [UBERON:0000930] +synonym: "mouth" BROAD [] +synonym: "stomodeal-hypophyseal primordium" BROAD [] +xref: UBERON:0000930 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000032 ! stomodeal-hypophyseal primordium +relationship: end_stage XAO:1000072 ! NF stage 60 +relationship: part_of XAO:0000001 ! ectoderm +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000270 +name: sensorial layer of neurectoderm +def: "Deep layer of the neural ectoderm, which undergoes early neuronal differentiation." [PMID:11832243] +synonym: "deep layer of neurectoderm" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0000271 +name: somatic layer of lateral plate mesoderm +def: "Layer of lateral plate mesoderm that forms the future body wall; it underlies the ectoderm." [UBERON:0004871] +xref: UBERON:0004871 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000311 ! lateral plate mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000026 ! NF stage 16 + +[Term] +id: XAO:0000272 +name: Jacobson's organ +def: "An auxiliary olfactory sense organ involved in the detection of pheromones." [http://en.wikipedia.org/wiki/Vomeronasal_organ] +synonym: "organon vomeronasale" EXACT [] +synonym: "VNO" EXACT [] +synonym: "vomeronasal organ" EXACT [] +xref: UBERON:0002255 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000273 ! olfactory organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000273 +name: olfactory organ +def: "Organ comprising the specialized structures subserving the function of the sense of smell." [BTO:0001772] +xref: UBERON:0002268 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000005 ! olfactory placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000274 +name: sperm entry point +def: "The point on the surface of the egg at which the sperm enters the egg." [XAO:EJS] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: part_of XAO:0000035 ! zygote +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000275 +name: olfactory pit +alt_id: XAO:0004073 +def: "A depression on the head of the embryo that becomes converted into a nasal passage." [http://www.merriam-webster.com/medical/olfactory%20pit] +synonym: "nasal pit" EXACT [] +xref: UBERON:0005870 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000005 ! olfactory placode +relationship: end_stage XAO:1000062 ! NF stage 50 +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000276 +name: splanchnic layer of lateral plate mesoderm +alt_id: XAO:0004273 +def: "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall; it overlies endoderm." [UBERON:0004872] +synonym: "splanchnic mesoderm" RELATED [] +synonym: "visceral mesoderm" RELATED [] +xref: UBERON:0004872 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000311 ! lateral plate mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000050 ! mesoderm +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000026 ! NF stage 16 + +[Term] +id: XAO:0000277 +name: choana +def: "The internal nasal passages, aperture or cavity in the roof of the buccopharynx." [ISBN:0226557634] +synonym: "choanae" RELATED PLURAL [] +synonym: "internal nares" RELATED [] +synonym: "posterior nasal apperture" EXACT [] +xref: UBERON:0004771 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000005 ! olfactory placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000278 +name: animal part, late involuting +def: "When the marginal zone mesoderm undergoes involution, where the marginal zone contacts the vegetal base." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000074 ! involuting marginal zone +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000279 +name: vegetal blastomere +def: "Unpigmented, larger blastomere of the vegetal (lower) hemisphere of the cleaving embryo." [ISBN:0471209627] +synonym: "macromere" RELATED [] +synonym: "vegetal hemisphere blastomere" EXACT [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0000280 ! vegetal hemisphere +relationship: end_stage XAO:1000017 ! NF stage 7 +relationship: part_of XAO:0000280 ! vegetal hemisphere +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) + +[Term] +id: XAO:0000280 +name: vegetal hemisphere +def: "Anatomical region that is the lower, light-colored hemisphere of the egg, as its cells contain large amounts of dense yolk proteins. The Xenopus egg is divided into two roughly equal halves: the animal and vegetal hemispheres." [XAO:curator] +xref: UBERON:0012285 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000281 +name: vegetal yolk mass +def: "Cell mass in the vegetal region of the embryo that will contribute to endoderm." [XAO:EJS] +synonym: "vegetal cell mass" EXACT [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0000282 +name: visceral pouch +def: "Pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits." [ISBN:0226557634] +synonym: "visceral pouches" RELATED PLURAL [] +xref: UBERON:0004117 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000232 ! foregut +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000283 +name: pupil +def: "A hole located in the center of the iris of the eye that allows light to enter the retina." [http://en.wikipedia.org/wiki/Pupil] +xref: UBERON:0001771 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000284 +name: epibranchial placode +def: "The three distinct placodal areas which develop from the posterior placodal area and lie ventral to the otic placode and dorsocaudal to the pharyngeal clefts, and contribute to the sensory ganglia for the distal portion of cranial nerves VII IX and X. The proximal neurons are derived from the neural crest." [ISBN:0878933840] +xref: UBERON:0003078 +is_a: XAO:0004620 ! neurogenic placode +relationship: develops_from XAO:0000187 ! dorsolateral placode region +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000285 +name: pronephric nephron +def: "The structure that is the basic functional unit of the pronephros." [UBERON:0005309] +synonym: "pronephric tubule" RELATED [] +xref: UBERON:0005309 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0002000 ! pronephric kidney +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000286 +name: late proximal tubule +def: "Portion of the pronephric tubule that is immediately posterior to the early proximal tubule and anterior to the early distal tubule." [PMID:15223337] +synonym: "late proximal segment" EXACT [] +synonym: "proximal tubule 3" EXACT [] +synonym: "proximal tubule segment 3" EXACT [] +synonym: "PT3" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004518 ! proximal tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000287 +name: early distal tubule +def: "Portion of the pronephric tubule that is immediately posterior to the late proximal tubule and anterior to the late distal segment." [PMID:15223337] +synonym: "distal early tubule" EXACT [] +synonym: "intermediate tubule" EXACT [] +synonym: "intermediate tubule segment 1" EXACT [] +synonym: "IT1" EXACT [] +synonym: "pronephric distal early tubule" EXACT [] +synonym: "pronephric early distal tubule" EXACT [] +xref: UBERON:0006337 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004519 ! distal tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000288 +name: early proximal tubule +def: "Portion of the pronephric tubule that is immediately anterior to the late proximal tubule." [PMID:15223337] +synonym: "proximal tubule 2" EXACT [] +synonym: "proximal tubule segment 2" EXACT [] +synonym: "PT2" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004518 ! proximal tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000289 +name: late distal tubule +def: "Pronephric segment immediately posterior to the early distal tubule and anterior to the pronephric duct." [PMID:15223337] +synonym: "distal tubule segment 1" EXACT [] +synonym: "DT1" EXACT [] +synonym: "late distal segment" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004519 ! distal tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000290 +name: obsolete pronephric nephron segment S1 +is_obsolete: true + +[Term] +id: XAO:0000291 +name: mesonephric mesenchyme +def: "The tissue made up of loosely connected mesenchymal cells in the mesonephros." [UBERON:0005323] +xref: UBERON:0005323 +is_a: XAO:0003046 ! mesenchyme +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000292 +name: mesonephric nephron +alt_id: XAO:0000145 +def: "The structure that is the basic functional unit of the adult or mesonephric kidney, consisting of the vascular loop of the glomerulus, the capsule, the nephrocoel, the nephric duct, the nephrostome and the nephric tubule." [ISBN:0521301521] +synonym: "nephron" RELATED [] +xref: UBERON:0005322 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000291 ! mesonephric mesenchyme +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000141 ! mesonephric kidney +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000293 +name: obsolete neural fold +is_obsolete: true +replaced_by: XAO:0004087 + +[Term] +id: XAO:0000294 +name: blastocoel +def: "The cavity of the blastula, a closed space that is invaded by early mesenchyme and later obliterated by the enlarging archenteron. It forms during embryogenesis when a zygote (a fertilized ovum) divides into many cells through mitosis." [ISBN:0023771100, ISBN:0815318960] +synonym: "blastocele" EXACT [] +synonym: "blastocyst cavity" RELATED [] +synonym: "cleavage cavity" RELATED [] +synonym: "segmentation cavity" RELATED [] +xref: UBERON:0000090 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000206 ! blastocoel anlage +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0000295 +name: central endoderm +def: "The portion of endoderm between dorsal and ventral blastopore lips, and extending towards to the blastocoel." [XAO:curators] +synonym: "endodermal yolk mass" RELATED [] +synonym: "vegetal endodermal core" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000026 ! NF stage 16 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0000296 +name: vegetal +def: "Anatomical direction relating to the vegetal pole or hemisphere." [XAO:EJS] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000297 +name: animal +def: "Anatomical direction relating to the animal pole or hemisphere." [XAO:curators] +subset: anatomical_site_slim +synonym: "animal hemisphere" RELATED [] +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000298 +name: dorsal +def: "Spatial concept denoting the back or upper surface of the body." [NCIt:Dorsal] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000299 +name: ventral +def: "Spatial concept denoting the underside or lower surface of the body." [NCIt:Ventral] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000300 +name: superficial +def: "Spatial concept denoting only the surface of the body." [XAO:EJS] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000301 +name: deep +def: "Spatial concept denoting extension relatively far inward." [NCIt:Deep] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000302 +name: dorso-lateral +def: "Spatial concept pertaining to the back of the body and to the side." [http://medical-dictionary.thefreedictionary.com/dorsolateral] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000303 +name: ventro-lateral +def: "Spatial concept pertaining to the part of the body opposite the back and away from the midline." [http://medical-dictionary.thefreedictionary.com/ventrolateral] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000304 +name: lateral +def: "Spatial concept pertaining to being situated at or extending to the side." [NCIt:Lateral] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0000305 +name: cranial placode +def: "A localized ectodermal thickening that develops by apicobasal elongation of cuboidal cells in the inner layer of the ectoderm in the head of the embryos, and is involved in formation of sense organs." [UBERON:0002546] +synonym: "cranial placodes" RELATED PLURAL [] +xref: UBERON:0002546 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000037 ! animal cap inner layer +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: develops_from XAO:0004104 ! neural plate border +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: part_of XAO:0000001 ! ectoderm +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000306 +name: floor plate +def: "Organizing center consisting of a small group of cells located at the ventral midline of the neural tube that influences the development of the nervous system, governing the specification of neuronal cell types and directing axonal trajectories." [PMID:15738958] +synonym: "floorplate" EXACT [] +synonym: "spinal cord floor" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000047 ! notoplate +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000307 +name: anterior neural tube +def: "Anterior segment of the neural tube, which develops into the forebrain and midbrain." [XAO:EJS] +xref: UBERON:0003080 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000045 ! pre-chordal neural plate +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000309 +name: marginal zone (sensu neural) +def: "Region of the neural tube that will become the white matter of the nervous system." [ISBN:0393974308] +subset: anatomical_site_slim +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000310 +name: anterior neural fold +def: "The anterior U-shaped portion of the neural folds, the two longitudinal dorsal ridges, caused by a folding up of the ectoderm, that make their appearance on either side of the middle line of the early neural embryo." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000045 ! pre-chordal neural plate +relationship: part_of XAO:0004087 ! neural fold +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000311 +name: lateral plate mesoderm +def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures." [UBERON:0003081] +synonym: "LPM" EXACT [] +xref: UBERON:0003081 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000050 ! mesoderm +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0000313 +name: head somite +def: "Any of the transient, degenerating somites that form in the occipital region of the animal." [XAO:curators] +synonym: "cranial somite" RELATED [] +synonym: "occipital somite" RELATED [] +xref: UBERON:0005594 +is_a: XAO:0000058 ! somite +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0000040 ! head region +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000314 +name: trunk somite +def: "Any of the somites that are posterior to the head and anterior to the tail." [XAO:EJS] +xref: UBERON:0005598 +is_a: XAO:0000058 ! somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000315 +name: myotome +def: "Somitic compartment that is a precursor of muscle." [PMID:17313522] +synonym: "myotomes" RELATED PLURAL [] +xref: UBERON:0003082 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0005080 ! dermomyotome +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000316 +name: epicardium +def: "The inner layer of the pericardium that is in contact with the surface of the heart. During cardiac development, it is the source of multipotent mesenchymal cells, which give rise to endothelial and smooth muscle cells in coronary vessels and also, possibly, to cardiomyocytes." [AAO:0010409, XAO:curators] +synonym: "heart epicardium" EXACT [] +xref: UBERON:0002348 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000336 ! heart primordium +relationship: develops_from XAO:0004482 ! epicardial precursor cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000318 +name: glomus +def: "Multi-tissue structure that is the filtration unit of the pronephric kidney. A glomus is a glomerulus that spans more than one body segment. It is the vascularized filter of the pronephric kidney. Blood is filtered through the glomus and the filtrate deposited into the coelom early in development, or the nephrocoel later in development. The glomus contains podocytes with well developed foot processes that are anatomically indistinguishable from the podocytes of adult glomeruli. The two glomera are linked via a narrow bridge called the glomeral nexus." [PMID:9268568, XAO:curators] +comment: Properly called a glomus as it extends over multiple body segments. +synonym: "corpuscle" RELATED [] +synonym: "glomera" RELATED PLURAL [] +synonym: "glomerulus" RELATED [] +synonym: "renal corpuscle" RELATED [] +xref: UBERON:0004739 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000110 ! glomeral mesenchyme +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0002000 ! pronephric kidney +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000319 +name: trunk neural crest +def: "Neural crest cells that migrate along two major pathways: through the somites, to populate the skin where they give rise to pigment cells; cells migrating along the lateral pathway generate sensory and sympathetic ganglia and adrenal chromaffin cells, among others." [ISBN:0878933840] +synonym: "TNC" EXACT [] +synonym: "trunk crest" RELATED [] +xref: UBERON:0003083 +is_a: XAO:0005327 ! chordal neural crest +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0000320 +name: sensorial layer +def: "The inner layer of ectoderm." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0000323 +name: profundus ganglion +def: "Type of ganglion that is separate distally from the trigeminal ganglia; they become fused at their proximal end as they condense." [PMID:21452441] +synonym: "cranial ganglion" RELATED [] +synonym: "profundus ganglia" RELATED PLURAL [] +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0004093 ! profundal placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000324 +name: hypobranchial placode +def: "A unique type of neurogenic placode, located ventral and caudal to the 2nd and 3rd pharyngeal pouches, which gives rise to small hypobranchial ganglia of yet unknown function." [PMID:12712315] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000187 ! dorsolateral placode region +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000326 +name: left spleen primordium +def: "Primordium of the spleen, which goes on to form the spleen proper, while the right splenic promordium degenerates." [XAO:curators] +synonym: "spleen" BROAD [] +xref: UBERON:0006293 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000327 +name: right spleen primordium +def: "Transient splenic primordia that degenerates by NF stage 40." [XAO:curators] +synonym: "spleen" BROAD [] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000328 +name: spleen +def: "Internal lymphoid organ the primary function of which is to filter blood." [XAO:EJS] +xref: UBERON:0002106 +is_a: XAO:0003034 ! viscus +is_a: XAO:0003041 ! compound organ +relationship: develops_from XAO:0000326 ! left spleen primordium +relationship: develops_from XAO:0000327 ! right spleen primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000329 +name: coelomic epithelium +def: "The epithelial lining of the coelom." [XAO:curators] +xref: UBERON:0005891 +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0000271 ! somatic layer of lateral plate mesoderm +relationship: develops_from XAO:0000276 ! splanchnic layer of lateral plate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000330 +name: Mullerian duct +def: "Transient developmental organ that gives rise to oviducts in females (and is documented to persist in some male frogs)." [AAO:0010141] +xref: UBERON:0003890 +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000076 ! NF stage 64 + +[Term] +id: XAO:0000331 +name: mesonephric early proximal tubule +def: "Structure that is equivalent to the convoluted proximal tubule of metanephric nephrons." [XAO:curators] +is_a: XAO:0000148 ! mesonephric tubule +relationship: develops_from XAO:0000292 ! mesonephric nephron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000332 +name: mesonephric late proximal tubule +def: "Structure that is the mesonephros nephron's equivalent to the straight proximal segment of a metanephric nephron." [XAO:curators] +synonym: "opisthonephros" RELATED [] +synonym: "proximal straight segment" RELATED [] +is_a: XAO:0000148 ! mesonephric tubule +relationship: develops_from XAO:0000292 ! mesonephric nephron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000333 +name: mesonephric early distal tubule +def: "The mesonephric equivalent of the ascending limb, or straight distal segment, of metanephric nephrons." [XAO:curators] +synonym: "ascending limb" RELATED [] +synonym: "straight distal segment" RELATED [] +xref: UBERON:0005892 +is_a: XAO:0000148 ! mesonephric tubule +relationship: develops_from XAO:0000292 ! mesonephric nephron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000334 +name: mesonephric late distal tubule +def: "The site of bicarbonate resorption in the adult kidney. It is equivalent to the convoluted distal segment of metanephric nephrons." [XAO:curators] +synonym: "mesonephric late distal segment" EXACT [] +is_a: XAO:0000148 ! mesonephric tubule +relationship: develops_from XAO:0000292 ! mesonephric nephron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000336 +name: heart primordium +def: "The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They give rise to the endocardium at NF stage 27/28." [XAO:curators] +synonym: "fused heart primordium" RELATED [] +synonym: "heart" BROAD [] +xref: UBERON:0003084 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0004185 ! primary heart field +relationship: develops_from XAO:0004186 ! secondary heart field +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000337 +name: endocardial tube +def: "Region in the embryo that consists of precursor cells for the development of the embryonic heart." [http://en.wikipedia.org/wiki/Endocardial_heart_tubes] +synonym: "heart tube" RELATED [] +xref: UBERON:0004141 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000066 ! endocardium +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000338 +name: ventral aorta +def: "The outlet of the embryonic heart; lies in the floor of the pharynx and conducts blood from the bulbus arteriosis to the aortic arches (1-6)." [ISBN:0023771100] +xref: UBERON:0003085 +is_a: XAO:0003010 ! aorta +relationship: develops_from XAO:0000337 ! endocardial tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000339 +name: left channel of ventral aorta +def: "Of the paired ventral aortas in the tadpole, the one that branches into the left aortic arches." [PMID:8928932] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000338 ! ventral aorta +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000340 +name: right channel of ventral aorta +def: "Of the paired ventral aortas in the tadpole, the one that branches into the right aortic arches." [PMID:8928932] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000338 ! ventral aorta +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000341 +name: aortic arch +def: "One of a series of six paired embryological vascular structures that give rise to several major arteries." [UBERON:0004363] +synonym: "aortic arches" RELATED PLURAL [] +xref: UBERON:0004363 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000339 ! left channel of ventral aorta +relationship: develops_from XAO:0000340 ! right channel of ventral aorta +relationship: develops_from XAO:0004190 ! cardiac neural crest +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000342 +name: aortic arch 1 +def: "The anterior member of a series of six paired arterial connections between the dorsal and ventral aortae. Aortic arch that is part of mandibular arch." [XAO:curators] +synonym: "first aortic arch" EXACT [] +xref: UBERON:0003118 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000343 +name: aortic arch 2 +def: "The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch that is part of hyoid arch." [ISBN:0023771100] +synonym: "second aortic arch" EXACT [] +xref: UBERON:0003119 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000344 +name: aortic arch 3 +def: "The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult." [ISBN:0023771100] +synonym: "third aortic arch" EXACT [] +xref: UBERON:0003120 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000345 +name: external carotid artery +def: "Artery that arises from the ventral aorta and delivers blood to the filter apparatus. It is visible as a bilateral pair of vessels on the ventral surface of the head, running between the heart and the tip of the jaw." [ISBN:0073524239, PMID:12606281] +synonym: "ECA" EXACT [] +xref: UBERON:0001070 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000338 ! ventral aorta +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000439 ! filter chamber +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000349 +name: larval aorta +def: "The aorta of a postembryonic, hatched or immature tadpole, prior to metamorphosis." [XAO:curators] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: develops_from XAO:0000344 ! aortic arch 3 +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0000351 +name: obsolete secondary vessel +is_obsolete: true + +[Term] +id: XAO:0000352 +name: aortic arch 5 +def: "The fifth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 5 artery is paired and has a common trunk with aortic arch 6 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. Aortic arches 5 and 6 supply the trunk and tail with oxygenated blood." [ISBN:0023771100] +synonym: "fifth aortic arch" EXACT [] +xref: UBERON:0003122 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000353 +name: aortic arch 6 +def: "The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood." [ISBN:0023771100] +synonym: "sixth aortic arch" EXACT [] +xref: UBERON:0003123 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000354 +name: posterior palatine artery +def: "One of three branches of the internal carotid artery, the palatine artery supplies the mouth region." [PMID:12606281] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000342 ! aortic arch 1 +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000366 ! internal carotid artery +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000355 +name: aortic arch 4 +def: "The fourth in a series of paired arterial connections between the dorsal and ventral aortae, it lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult." [ISBN:0023771100] +synonym: "fourth aortic arch" EXACT [] +synonym: "systemic arch" RELATED [] +xref: UBERON:0003121 +is_a: XAO:0000341 ! aortic arch +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000356 +name: vascular endothelium +def: "Simple squamous epithelium that lines blood and lymphatic vessels and the heart." [XAO:EJS, ZFA:0001639] +synonym: "vascular endothelia" RELATED PLURAL [] +xref: UBERON:0004852 +is_a: XAO:0004010 ! simple squamous epithelium +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000357 +name: arterial endothelium +def: "The thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall." [XAO:curators] +synonym: "endothelium of artery" RELATED [] +xref: UBERON:0001917 +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0000356 ! vascular endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000114 ! artery +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000358 +name: venous endothelium +def: "Simple squamous epithelium that lines the veins." [XAO:EJS] +xref: UBERON:0001919 +is_a: XAO:0004010 ! simple squamous epithelium +relationship: develops_from XAO:0000356 ! vascular endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000115 ! vein +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000361 +name: arteria iliaca communis +def: "The blood vessel that bifurcates from the aorta, and supplies the abdominal and pelvic regions." [ISBN:0070179778] +synonym: "common iliac artery" EXACT [] +xref: UBERON:0005609 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000061 ! NF stage 49 + +[Term] +id: XAO:0000362 +name: coeliaco-mesenteric artery +def: "Artery consisting of many branches which supply blood to various organs in the viscus. One of the major blood vessels, branching off the dorsal aorta and supplying the embryonic foregut organs: liver, stomach, intestine, spleen and pancreas." [AAO:0010499, ISBN:0070179778] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000363 +name: occipitovertebral artery +def: "One of paired arteries that extends dorsally from the systemic arch to supply the muscles of the jaw and back." [ISBN:0801836018] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000364 +name: caudal artery +def: "The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis." [ISBN:0226557634] +synonym: "CA" EXACT [] +xref: UBERON:0003086 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004151 ! tail vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000365 +name: arteria subclavia +def: "Artery that branches from either side of the dorsal aorta and delivers blood to the musculature of the shoulder region." [ISBN:0070179778] +synonym: "subclavian artery" EXACT [] +xref: UBERON:0001533 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000363 ! occipitovertebral artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0000366 +name: internal carotid artery +def: "One of the major arteries of the head, it is the cranial continuation of the aortic arches and the dorsal aorta. It curves ventrally before resuming a dorsal course as it enters the head proper, and it lies ventral to the internal jugular vein. The internal carotid artery gives off palatine, ophthalmic, and cerebral branches by NF stage 41." [PMID:12606281] +synonym: "ICA" EXACT [] +xref: UBERON:0001532 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000367 +name: cerebral artery +def: "The anterior continuation of the internal carotid artery, which gives off the nasociliary artery anterior to the eye." [PMID:12606281] +xref: UBERON:0004449 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000366 ! internal carotid artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000366 ! internal carotid artery +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000368 +name: ophthalmic artery +def: "A branch of the internal carotid artery that delivers blood to the eye. Together with the opthalmic vein, it forms a double ring encircling the eye and retina. It enters the eye obliquely by crossing over the ophthalmic vein and the internal jugular vein." [PMID:12606281] +xref: UBERON:0001619 +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000366 ! internal carotid artery +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000369 +name: anterior palatine artery +def: "One of three branches of the internal carotid artery, it supplies the mouth region." [PMID:12606281] +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000366 ! internal carotid artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000366 ! internal carotid artery +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000370 +name: arteria mesenterica posterior +def: "The artery that supplies the network of blood vessels (the mesentry) to the large intestine." [ISBN:0070179778] +synonym: "posterior mesenteric artery" EXACT [] +xref: UBERON:0005616 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000361 ! arteria iliaca communis +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000062 ! NF stage 50 + +[Term] +id: XAO:0000371 +name: right lymph heart +def: "The rightmost of the two bilaterally symmetrical lymph hearts that can be seen adjacent to somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43. Lymph hearts are pulsatile organs, present in lower vertebrates, that function to propel lymph into the venous system." [PMID:12606281, PMID:20067786] +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003199 ! lymphatic system +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000372 +name: left lymph heart +def: "The leftmost of the two lymph hearts, pulsatile organs that are present in lower vertebrates and function to propel lymph into the venous system. Two bilaterally symmetrical lymph hearts can be seen adjacent to the somites 3 and 4 by NF stage 40, and can be seen beating by NF stage 43." [PMID:12606281, PMID:20067786] +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003199 ! lymphatic system +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000373 +name: duct of Cuvier +def: "Bilaterally paired longitudinal vein; the anterior cardinal returns blood from the head, and the posterior cardinal returns it from the trunk; these two vessels join together on each side as the common cardinal vein, also known as the duct of Cuvier that leads to the heart's sinus venosus." [XAO:EJS, ZFA:0000186] +synonym: "common cardinal vein" RELATED [] +xref: UBERON:0002064 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000374 +name: dorsal lymph space +def: "Large subdermal lymph-containing space located dorsally near the last vertebrae." [XAO:EJS] +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000371 ! right lymph heart +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003199 ! lymphatic system +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000375 +name: lymph vessel +def: "A vessel that contains or conveys lymph." [AAO:0011005] +synonym: "lymphatic vessel" RELATED [] +xref: UBERON:0001473 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000372 ! left lymph heart +relationship: develops_from XAO:0000374 ! dorsal lymph space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0001010 ! circulatory system +relationship: part_of XAO:0003199 ! lymphatic system +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000376 +name: omphalomesenteric vein +def: "Any of the veins in the embryo that return blood from the yolk sac to the heart or later to the portal vein." [http://www.merriam-webster.com/medical/omphalomesenteric%20vein] +xref: UBERON:0005487 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000377 +name: capillary system of liver +def: "The smallest of the blood vessels, parts of the microcirculation, of the liver." [XAO:curators] +synonym: "liver capillary" EXACT [] +is_a: XAO:0000116 ! capillary +relationship: develops_from XAO:0000376 ! omphalomesenteric vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000133 ! liver +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000378 +name: musculoabdominal vein +def: "Ventrolateral component of the external jugular vein." [PMID:12606281] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000379 +name: external jugular vein +def: "One of the bilateral pairs of vessels clearly seen on the ventral surface of the head, running between the heart and the tip of the jaw, and draining the filter apparatus. This vein is more developed by NF stage 45, when it crosses the head dorsolaterally to drain into the Duct of Cuvier and pronephric sinus." [PMID:12606281] +synonym: "external jugular" EXACT [] +xref: UBERON:0001101 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000380 +name: lateral postcardinal vein +def: "Vein that first appears as disconnected portions lateral to the Wolffian ducts at NF stage 44, gradually becoming continuous. They come into communication with the medial postcardinals at the kidney sinus." [ISBN:0815318960] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0000381 +name: mesonephric sinus +def: "Sinus that surrounds the mesonephric tubules and puts lateral and medial postcardinal veins into communication with each other." [ISBN:0815318960] +xref: UBERON:0006196 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000380 ! lateral postcardinal vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000140 ! urogenital system +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0000382 +name: internal jugular vein +def: "The main dorsal head vein, it drains into the Duct of Cuvier, and collects blood from the dorsal jaw region, cerebral veins, the ophthalmic vein and the short pharyngeal vein. It forms loop around the olfactory bulb by NF stage 43." [PMID:12606281] +xref: UBERON:0001586 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000383 +name: anterior cardinal vein +def: "Vein that returns blood from the dorsal head and drains into the duct of Cuvier via the pronephric sinus." [PMID:12606281] +synonym: "ACV" EXACT [] +xref: UBERON:0003087 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000052 ! cardinal vein +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000384 +name: medial cardinal vein +def: "Vein that gives rise to the interrenal vein and pronephric sinus." [XAO:EJS] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000052 ! cardinal vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000385 +name: pronephric sinus +def: "A system of vessels that initially swell from where the anterior and posterior cardinal veins meet before draining into the heart via the duct of Cuvier at NF stage 33 and 34, and then continue to narrow and fold into a characteristic S-shape by NF stage 37 and 38. It continues to loop on itself, at first a loose, then a dense knot of many vessels by NF stage 45." [PMID:12606281] +xref: UBERON:0006174 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000373 ! duct of Cuvier +relationship: develops_from XAO:0000383 ! anterior cardinal vein +relationship: develops_from XAO:0000384 ! medial cardinal vein +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0002000 ! pronephric kidney +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0000386 +name: interrenal vein +def: "Vein formed from fusion of the posterior cardinal veins and that extends caudally." [ISBN:0226557626] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000384 ! medial cardinal vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000387 +name: hepatic vein +def: "Vein that carries blood away from the liver." [XAO:EJS, ZFA:0000670] +xref: UBERON:0001143 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000388 +name: posterior vena cava +def: "Vein that carries de-oxygenated blood from the posterior part of the body to the sinus venosus." [XAO:EJS] +xref: UBERON:0001072 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000386 ! interrenal vein +relationship: develops_from XAO:0000387 ! hepatic vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0000389 +name: gastric vein +def: "One of the veins of the alimentary system. The subintestinal vein is on the right side of the gut and drains the gastric vein on its right side by NF stage 43. The gastric veins carry blood low in oxygen from the surface of the stomach, draining into the left omphalomesenteric vein." [ISBN:0226557634, PMID:12606281] +xref: UBERON:0004450 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000390 +name: caudal vein +def: "Vein in the tail returning blood from the trunk and tail to the heart, leading directly into the posterior cardinal vein in the posterior trunk." [XAO:curators] +synonym: "CV" EXACT [] +xref: UBERON:0003088 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000386 ! interrenal vein +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004151 ! tail vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000391 +name: subinterstitial vein +def: "Vein that carries away fluid in the interstitial spaces." [XAO:curators] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0000392 +name: hepatic portal vein +def: "Vein that starts in capillaries of the alimentary canal and ends in capillaries of the liver." [XAO:EJS] +synonym: "portal vein" RELATED [] +xref: UBERON:0002017 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000393 +name: tail vein +def: "Vein in the tail returning blood from the tail to the heart." [XAO:EJS, ZFA:0000180] +xref: UBERON:0003481 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004151 ! tail vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000394 +name: pulmonary vein +def: "Any of the veins that collect blood from the lungs and some small vesicles received from the esophagus." [AAO:0010521] +xref: UBERON:0002016 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000395 +name: medial abdominal vein +def: "Vein in the posterior region that drains the ventral abdominal wall." [ISBN:0815318960] +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000054 ! NF stage 42 + +[Term] +id: XAO:0000396 +name: head somite 1 +def: "Transient occipital somite that exists from NF stages 17 to 26 only." [XAO:curators] +synonym: "somite W" EXACT [PMID:2769206] +is_a: XAO:0000313 ! head somite +relationship: end_stage XAO:1000042 ! NF stage 26 +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000397 +name: sclerotome +def: "Somitic compartment that is a precursor of the axial skeleton." [XAO:curators] +synonym: "sclerotomes" RELATED PLURAL [] +xref: UBERON:0003089 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000058 ! somite +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000399 +name: tendon fibroblast +def: "An elongated fibroblast type cell, the cytoplasm of which is stretched between the collagen fibres of the tendon." [http://en.wikipedia.org/wiki/Tendon_cell] +is_a: XAO:0003017 ! fibroblast +relationship: develops_from XAO:0000397 ! sclerotome +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000401 +name: sclerotomal cartilage +def: "Sclerotome cells of the cartilage fate." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000397 ! sclerotome +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000397 ! sclerotome +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000403 +name: head somite 2 +def: "Transient occipital somite that exists from NF stages 18 to 29 only." [XAO:curators] +synonym: "somite X" EXACT [PMID:2769206] +is_a: XAO:0000313 ! head somite +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000404 +name: head somite 3 +def: "Transient occipital somite that exists from NF stages 18 to 29/30 only." [XAO:curators] +synonym: "somite Y" EXACT [PMID:2769206] +is_a: XAO:0000313 ! head somite +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000405 +name: head somite 4 +def: "Transient occipital somite that exists from NF stages 19 to late 30's." [XAO:curators] +synonym: "somite Z" EXACT [PMID:2769206] +is_a: XAO:0000313 ! head somite +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0000406 +name: trunk somite 1 +def: "Trunk somite that is initially the fifth somite, first forming around NF stage 19 and becoming more anteriorly positioned as the head somites degenerate. It is the most anterior somite by NF stage 45 and is adjacent to the otic vesicle." [ISBN:0815318960] +synonym: "fifth somite" RELATED [] +synonym: "somite 1" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000407 +name: trunk somite 2 +def: "Trunk somite that is initially the sixth somite and later becomes the secondmost anterior somite." [ISBN:0815318960] +synonym: "sixth somite" RELATED [] +synonym: "somite 2" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0000408 +name: trunk somite 3 +def: "The 1st somite located posterior to the head." [XAO:EJS] +synonym: "somite 3" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0000409 +name: trunk somite 4 +def: "The 2nd somite located posterior to the head." [XAO:EJS] +synonym: "somite 4" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0000410 +name: trunk somite 5 +def: "The 3rd somite located posterior to the head." [XAO:EJS] +synonym: "somite 5" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000411 +name: trunk somite 6 +def: "The 4th somite located posterior to the head." [XAO:EJS] +synonym: "somite 6" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0000412 +name: trunk somite 7 +def: "The 5th somite located posterior to the head." [XAO:EJS] +synonym: "somite 7" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000414 +name: sclerotomal mesenchyme +def: "Mesenchymal cells that break from the sclerotome. Such cells migrate from the somite to surround the notochord." [ISBN:0123190606] +is_a: XAO:0003046 ! mesenchyme +relationship: develops_from XAO:0000397 ! sclerotome +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000397 ! sclerotome +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0000415 +name: notochordal sheath +def: "Mesenchymal covering surrounding the notochord, derived from sclerotomal mesenchyme." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000414 ! sclerotomal mesenchyme +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000416 +name: trunk somite 8 +def: "The 6th somite located posterior to the head." [XAO:EJS] +synonym: "somite 8" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000417 +name: trunk somite 9 +def: "The 7th somite located posterior to the head." [XAO:EJS] +synonym: "somite 9" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0000418 +name: trunk somite 10 +def: "The 8th somite located posterior to the head." [XAO:EJS] +synonym: "somite 10" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000419 +name: trunk somite 11 +def: "The 9th somite located posterior to the head." [XAO:EJS] +synonym: "somite 11" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000420 +name: trunk somite 12 +def: "The 10th somite located posterior to the head." [XAO:EJS] +synonym: "somite 12" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0000421 +name: trunk somite 13 +def: "The 11th somite located posterior to the head." [XAO:EJS] +synonym: "somite 13" EXACT [] +is_a: XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0000422 +name: tail somite 14 +def: "The 12th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS] +synonym: "somite 14" EXACT [] +synonym: "trunk somite 14" EXACT [] +is_a: XAO:0003143 ! tail somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0000423 +name: tail somite 15 +def: "The 13th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS] +synonym: "somite 15" EXACT [] +synonym: "trunk somite 15" EXACT [] +is_a: XAO:0003143 ! tail somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000424 +name: tail somite 16 +def: "The 14th somite located posterior to the head. This somite forms at NF stage 28, by which time head somite 1 has degenerated, and it is resorbed at metamorphosis." [XAO:curators] +synonym: "somite 16" EXACT [] +synonym: "trunk somite 16" EXACT [] +is_a: XAO:0003143 ! tail somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000425 +name: tail somite 17 +def: "The 15th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS] +synonym: "somite 17" EXACT [] +synonym: "trunk somite 17" EXACT [] +is_a: XAO:0003143 ! tail somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000426 +name: olfactory nerve +def: "Cranial nerve that supplies the nasal organ. It leaves the olfactory lobe, passes through the fenestra olfactoria into the nasal capsule, and there divides into the ramus profundus and ramus dorsalis." [ISBN:0471209627, ISBN:080184780X] +synonym: "cranial nerve I" EXACT [] +xref: UBERON:0001579 +is_a: XAO:0000429 ! cranial nerve +relationship: develops_from XAO:0000005 ! olfactory placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000427 +name: gasserian ganglion +def: "Sensory ganglion of the trigeminal nerve." [http://en.wikipedia.org/wiki/Trigeminal_ganglion] +synonym: "gasserian ganglia" RELATED PLURAL [] +xref: UBERON:0001675 +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0000225 ! trigeminal placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000428 +name: trigeminal ganglion +def: "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear." [UBERON:0001675] +synonym: "trigeminal ganglia" RELATED PLURAL [] +synonym: "trigeminus ganglion" RELATED [] +xref: UBERON:0001675 +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0000225 ! trigeminal placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0000429 +name: cranial nerve +alt_id: XAO:0003089 +def: "Any of the major paired nerves of the head or cephalic region. Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. They are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves." [XAO:curators] +synonym: "cephalic nerve" RELATED [] +synonym: "cranial nerves" RELATED [] +xref: UBERON:0001785 +is_a: XAO:0005309 ! cephalic nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000430 +name: Rathke's pouch +def: "A depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system." [UBERON:0005356] +xref: UBERON:0005356 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000269 ! mouth primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000269 ! mouth primordium +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000431 +name: tooth +def: "Each of a set of hard, bony enamel-coated structures in the jaws, used for biting." [AEO:0000220] +synonym: "dentition" BROAD [] +synonym: "teeth" RELATED PLURAL [] +xref: UBERON:0001091 +is_a: XAO:0004012 ! skeletal element +relationship: develops_from XAO:0000269 ! mouth primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000072 ! NF stage 60 + +[Term] +id: XAO:0000437 +name: death +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that corresponds to the end of the animal's life." [XAO:EJS] +xref: UBERON:0000071 +is_a: XAO:1000000 ! Xenopus developmental stage +relationship: preceded_by XAO:1000095 ! post-embryonic stage + +[Term] +id: XAO:0000439 +name: filter chamber +def: "The structure that enables tadpoles, which are suspension feeders, to trap food particles. The palatoquadrate, ceratohyal and the connecting muscles are responsible for the irrigation and ventilation of the filter apparatus." [XAO:curators] +synonym: "coelom" RELATED [] +synonym: "coelomic filter chamber" RELATED [] +synonym: "filter apparatus" EXACT [] +synonym: "peribranchial chamber" EXACT [] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000440 +name: lateral line placode +def: "Thickened placodal areas located anterior and posterior to the otic vesicle. There are 5 distinct lateral line placodes, each giving rise to a single lateral line nerve that will innervate lateral line hair cells and convey information on motion to the adjacent hindbrain." [ISBN:0878933840] +synonym: "lateral line" BROAD [] +synonym: "lateral line placodes" RELATED PLURAL [] +xref: UBERON:0009128 +is_a: XAO:0004620 ! neurogenic placode +relationship: develops_from XAO:0004207 ! posterior placodal area +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: part_of XAO:0000095 ! lateral line system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0000441 +name: infraorbital lateral line primordium +def: "Lateral line primordium that migrates ventrad along the posterior and ventral margin of the eye." [PMID:2652193] +is_a: XAO:0004411 ! lateral line primordium +relationship: develops_from XAO:0000440 ! lateral line placode +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000442 +name: supraorbital lateral line +def: "Lateral line situated along the dorsal margin of the eye." [PMID:2652193] +xref: UBERON:0003090 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000440 ! lateral line placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000443 +name: trunk lateral line +def: "A lateral line that is present on the trunk of the organism." [XAO:EJS] +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000440 ! lateral line placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000444 +name: thyroid primordium +def: "The initial thyroid precursor, which arises from the ventral aspect of the second pharyngeal pouch." [UBERON:0003091] +synonym: "thyroid" BROAD [] +xref: UBERON:0003091 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000105 ! pharyngeal cavity +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000445 +name: taste bud +def: "The organ used for chemoreception." [AAO:0010573] +xref: UBERON:0001727 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000105 ! pharyngeal cavity +relationship: develops_from XAO:0000446 ! tongue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003197 ! gustatory system +relationship: start_stage XAO:1000063 ! NF stage 51 + +[Term] +id: XAO:0000446 +name: tongue +def: "The movable, muscular organ on the floor of the mouth." [UBERON:0001723] +xref: UBERON:0001723 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000097 ! mandibular arch +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000447 +name: branchial arch 1 +def: "The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, containing the first aortic arch." [ISBN:0023771100] +synonym: "first branchial arch" EXACT [] +synonym: "third visceral arch" RELATED [] +xref: UBERON:0003114 +is_a: XAO:0000099 ! branchial arch +relationship: develops_from XAO:0000251 ! visceral pouch 3 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000448 +name: gill primordium +def: "A swelling from the 3rd visceral arch at NF stage 35 and 36, which co-occurs with a depression between the 3rd and 6th, forming the external gills by NF stage 39." [XAO:curators] +synonym: "external gill anlage" RELATED [] +synonym: "gill" BROAD [] +xref: UBERON:0008894 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000050 ! mesoderm +relationship: develops_from XAO:0000447 ! branchial arch 1 +relationship: develops_from XAO:0000449 ! branchial arch 2 +relationship: develops_from XAO:0004524 ! pharyngeal mesenchyme +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0000117 ! respiratory system +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000449 +name: branchial arch 2 +def: "The second pharyngeal/branchial arch; it arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature." [ISBN:0023771100] +synonym: "fourth visceral arch" RELATED [] +synonym: "second branchial arch" EXACT [] +xref: UBERON:0003115 +is_a: XAO:0000099 ! branchial arch +relationship: develops_from XAO:0000254 ! visceral pouch 4 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0000451 +name: branchial arch 3 +def: "The third in a series of paired bars in the wall of the pharynx, within which are formed the third aortic arch and the cartilage bar of the visceral skeleton, and forms and supports the gills." [ISBN:0023771100] +synonym: "fifth visceral arch" RELATED [] +synonym: "third branchial arch" EXACT [] +xref: UBERON:0003116 +is_a: XAO:0000099 ! branchial arch +relationship: develops_from XAO:0000255 ! visceral pouch 5 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000452 +name: ultimobranchial body +def: "Anatomical structure that includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch." [AAO:0010547] +xref: UBERON:0003092 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000453 ! branchial arch 4 +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000453 +name: branchial arch 4 +def: "The fourth in a series of paired bars in the wall of the pharynx, within which are formed the fourth aortic arch and the cartilage bar of the visceral skeleton; forms and supports the gills." [ISBN:0023771100] +synonym: "fourth branchial arch" EXACT [] +synonym: "sixth visceral arch" RELATED [] +xref: UBERON:0003117 +is_a: XAO:0000099 ! branchial arch +relationship: develops_from XAO:0000265 ! visceral pouch 6 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000454 +name: liver parenchyme +def: "The functional units of the liver including the lobules." [UBERON:0001280] +xref: UBERON:0001280 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000133 ! liver +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000455 +name: biliary tree +def: "Hollow tree organ, the organ parts of which consist of the bile ducts." [UBERON:0001173] +synonym: "biliary tract" RELATED [] +xref: UBERON:0001173 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000132 ! liver and biliary system +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0000457 +name: pyloric sphincter +def: "Sphincter muscle that is part of the pyloric region of the stomach." [UBERON:0001202] +xref: UBERON:0001202 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005130 ! distal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005158 ! pylorus +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0000458 +name: occipital lateral line +def: "A short lateral line that extends from the ear in a posterior-dorsal direction." [PMID:2652193] +xref: UBERON:0003093 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000440 ! lateral line placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0000459 +name: infraorbital lateral line +def: "Lateral line situated along the posterior and ventral margin of the eye." [PMID:2652193] +xref: UBERON:0003094 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000460 +name: hyomandibular lateral line +def: "Lateral line complex that radiates on the ventral side of the head from a point between the eye and the base of the larval tentacle." [PMID:2652193] +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000441 ! infraorbital lateral line primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0000461 +name: trunk placode +def: "Thickened plate of ectoderm that contributes to the formation of the dorsal, middle, or ventral lateral line." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0000462 +name: dorsal lateral line +def: "The dorsal-most part of the sensory system on the surface of the tadpole consisting of small sensory patches (neuromasts) distributed in discrete lines over the body surface. The lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the tadpole through the water, as well as facilitating schooling, prey capture, and predator and obstacle avoidance." [XAO:curators] +xref: UBERON:0003095 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000461 ! trunk placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000463 +name: middle lateral line +def: "A lateral line that extends from the ear in a posterior direction between the upper and lower lateral lines." [PMID:2652193] +xref: UBERON:0003096 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000461 ! trunk placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000464 +name: ventral lateral line +def: "Ventrally located lateral line that runs over the abdomen." [XAO:EJS] +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000461 ! trunk placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0000465 +name: caudal lateral line +def: "Cranial nerve of the caudal lateral line that enters the brain between cranial nerves VIII and IX; contains afferents and sensory efferents to the posterior lateral line ganglion and middle ganglion. Fibers from the posterior lateral line ganglion innervate the occipital dorsal lateral line and trunk lateral lines." [XAO:curators] +xref: UBERON:0006334 +is_a: XAO:0004002 ! lateral line +relationship: develops_from XAO:0000464 ! ventral lateral line +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0000467 +name: dorsal pancreatic bud +def: "The pancreatic bud that gives rise to the accessory pancreatic duct." [XAO:curators] +synonym: "pancreas" BROAD [] +synonym: "primary pancreatic bud" EXACT [] +xref: UBERON:0003923 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000469 +name: dorsal tail fin +def: "The dorsal part of the tail fin." [XAO:EJS] +xref: UBERON:0003097 +is_a: XAO:0000002 ! fin +relationship: develops_from XAO:0000319 ! trunk neural crest +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004062 ! tail fin +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0000470 +name: unicellular gland +def: "Any of the large number of glands of the larval skin, particularly common in the fins and adjacent skin of the trunk; also formed in the former frontal gland area on the upper jaw." [ISBN:0815318960] +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000320 ! sensorial layer +relationship: end_stage XAO:1000010 ! juvenile frog stage +relationship: start_stage XAO:1000062 ! NF stage 50 + +[Term] +id: XAO:0000471 +name: xanthophore +def: "A type of colored melanophore (mobile pigment cells of the dermis and epidermis) that contain fat-soluble carotenoids (obtained from the diet) and pteridines (synthesized from the cell) which are stored in pterinosomes. Their color depends on the pattern of carotenoids and pteridines. They are rarely found in pre-metamorphic larvae." [CL:0000430, ISBN:0226557634] +xref: CL:0000430 +is_a: XAO:0003014 ! pigment cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0000472 +name: iridophore +def: "A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platets or iridisomes. The color-generating components produce a silver, gold, or iridescent color." [AAO:0010318] +synonym: "guanophore" RELATED [] +xref: CL:0000431 +is_a: XAO:0003014 ! pigment cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0000474 +name: choroid fissure +def: "Part of the eye that forms during the transition from optic vesicle to optic cup as a groove at the lateroventral edge of the optic vesicle, which expands medially. The ventral edges of the optic vesicle then wrap around the fissure and fuse with one another, ultimately leading to a channel through which blood vessels and optic nerve fibres pass." [PMID:24478172] +synonym: "optic fissure" RELATED [] +synonym: "ventral choroidal fissure" RELATED [] +xref: UBERON:0005412 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000228 ! optic vesicle +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0000475 +name: optic stalk +def: "Neural tissue comprising the proximal part of either of the optic vesicles as they project towards the sides of the head; it remains narrow and constitutes the optic stalk (the peripheral part of each expands to form a hollow bulb)." [UBERON:0003098, XAO:curators] +xref: UBERON:0003098 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000228 ! optic vesicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0001001 +name: cranial neural crest +def: "The most anterior of 5 distinct and partially overlapping functional domains of the premigratory neural crest, which are intially part of the neural epithelium. CNC cells migrate through the extracelluar matrix in 4 highly conserved streams: the mandibular crest, hyoid crest, anterior branchial crest and the posterior branchial crest." [XAO:curators] +synonym: "cephalic neural crest" RELATED [] +synonym: "CNC" EXACT [] +synonym: "head crest" RELATED [] +xref: UBERON:0003099 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0001002 +name: lung primordium +def: "Anterior endoderm that develops into the lung buds, and in turn, the lungs. A pair of lateral diverticula just over the liver rudiment is formed by the floor of the foregut just anterior to the liver diverticulum." [ISBN:0815318960, XAO:curators] +synonym: "lateral diverticula" RELATED [] +synonym: "lung" BROAD [] +xref: UBERON:0005597 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000117 ! respiratory system +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0001010 +name: circulatory system +def: "Anatomical system that has as its parts the blood and lymph vessels." [XAO:curators] +synonym: "vascular system" EXACT [] +xref: UBERON:0004535 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0001011 +name: blood vessel +def: "Any of the vessels through which blood circulates in the body." [BTO:0001102] +synonym: "blood vessels" RELATED PLURAL [] +synonym: "vasculature" RELATED [] +xref: UBERON:0001981 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: part_of XAO:0001010 ! circulatory system +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0001012 +name: Stirnorgan +def: "Structure that is part of the pineal system, is located in the skin on the dorsal surface of the head, and is exposed continuously to ambient illumination." [DOI:10.1007/BF00663609] +synonym: "frontal organ" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000160 ! pineal gland +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003198 ! visual system +relationship: start_stage XAO:1000054 ! NF stage 42 + +[Term] +id: XAO:0001013 +name: musculature of face +def: "Muscle tissue forming the facial muscles, a group of striated muscles innervated by the facial nerves." [XAO:curators] +synonym: "facial muscle" EXACT [] +synonym: "facial muscles" EXACT PLURAL [] +xref: UBERON:0001577 +is_a: XAO:0000172 ! muscle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0001014 +name: melanophore +def: "A pigment cell that contains melanin (a brownish-black pigment), is derived from the neural crest, and is patchily distributed in the epidermis of the tadpole." [XAO:CJZ] +comment: General convention refers to "melanophores" in lower vertebrates and "melonocytes" in amniotes but there is little if any difference between cell types. +synonym: "melanocyte" RELATED [] +xref: CL:0000148 +is_a: XAO:0003014 ! pigment cell +relationship: develops_from XAO:0004510 ! melanoblast +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0001015 +name: rectal diverticulum +def: "Paired outgrowths of the cloaca that link the pronephric ducts to the exterior of the organism." [UBERON:0006172, XAO:curators] +synonym: "rectal diverticula" RELATED PLURAL [] +xref: UBERON:0006172 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000244 ! cloaca +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000143 ! urinary system +relationship: part_of XAO:0000244 ! cloaca +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0001016 +name: abdominal myoblast +def: "The myoblast that forms the muscles of the anterior abdominal walls." [AAO:0010314] +synonym: "abdominal musculature" RELATED [] +is_a: XAO:0003015 ! myoblast +relationship: develops_from XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000315 ! myotome +relationship: part_of XAO:0003230 ! trunk musculature +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0001017 +name: connective tissue +def: "Portion of tissue that consists of mesodermally derived cells and intercellular matrix composed of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues." [XAO:EJS, ZFA:0001632] +synonym: "portion of connective tissue" EXACT [] +xref: UBERON:0002384 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0001018 +name: anterior lymph sac +def: "The protrusion of mesenchymal tissue of the anterior cardinal vein which forms lymph sacs." [PMID:17062017] +synonym: "rostral lymph sac" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000358 ! venous endothelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003199 ! lymphatic system +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0001019 +name: proctodeum +def: "Inward fold on the surface of the embryonic ectoderm that develops into the common cloacal passage. The most posterior section of the larval alimentary system." [XAO:curators, ZFA:0000066] +synonym: "anus" RELATED [] +synonym: "anus porus" RELATED [] +synonym: "proctodaeum" EXACT [] +synonym: "vent" RELATED [] +xref: UBERON:0000931 +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000001 ! ectoderm +relationship: develops_from XAO:0000082 ! circumblastoporal collar +relationship: develops_from XAO:0000208 ! blastopore +relationship: develops_from XAO:0004091 ! non-neural ectoderm +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0005230 ! larval alimentary system +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0001020 +name: elastica externa +def: "Notochordal membrane covering derived from notochordal epithelium. Its first indication is at NF stage 24, and it is a distinct membrane by NF stage 28." [ISBN:0815318960] +synonym: "notochordal sheath" RELATED [] +xref: UBERON:0013655 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000055 ! notochord +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0001021 +name: notochordal epithelium +def: "Outer layer of cells of the differentiating notochord, which give rise to the elastica externa and interna." [http://dev.biologists.org/content/1/4/411.abstract] +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0000055 ! notochord +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0001101 +name: first pancreatic bud +def: "One of two pancreatic primordia that give rise to a ventral pancreatic bud." [XAO:EJS] +synonym: "pancreas" BROAD [] +xref: UBERON:0003921 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0001102 +name: second pancreatic bud +def: "Second of two pancreatic primordia that give rise to a ventral pancreatic bud." [XAO:EJS] +synonym: "pancreas" BROAD [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0001103 +name: ventral pancreatic bud +def: "Either of the two ventral pancreas rudiments that join and fuse with the right end of the dorsal pancreatic rudiment." [ISBN:0815318960] +synonym: "pancreas" BROAD [] +xref: UBERON:0003924 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0001101 ! first pancreatic bud +relationship: develops_from XAO:0001102 ! second pancreatic bud +relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell +relationship: end_stage XAO:1000057 ! NF stage 45 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0002000 +name: pronephric kidney +def: "Transient embryonic organ that serves as a kidney, providing osmoregulation during early developmental stages, and then degenerates during metamorphosis (starting at NF stage 53) as the mesonephric kidney develops and becomes functional." [XAO:curators] +subset: frequent_anatomy_items +synonym: "head kidney" RELATED [] +synonym: "pronephros" RELATED [] +synonym: "vorniere" RELATED [] +xref: UBERON:0002120 +is_a: XAO:0003037 ! multi-tissue structure +is_a: XAO:0005243 ! embryonic kidney +relationship: develops_from XAO:0000264 ! pronephric mesenchyme +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004521 ! coelom +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003000 +name: anatomical structure +def: "Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome." [CARO:0000003] +xref: CARO:0000003 +xref: UBERON:0000061 +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0003001 +name: anatomical group +def: "Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue." [CARO:0000054] +xref: CARO:0000054 +xref: UBERON:0000480 +is_a: XAO:0003000 ! anatomical structure +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003002 +name: anatomical system +def: "Anatomical group that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity." [CARO:0000011] +xref: CARO:0000011 +xref: UBERON:0000467 +is_a: XAO:0003001 ! anatomical group +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003003 +name: unspecified +def: "Unspecified Xenopus anatomical entity." [XAO:EJS] +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003004 +name: whole organism +def: "Anatomical structure that is an individual member of Xenopus laevis." [CARO:0000012] +subset: organism_views +subset: sectional_anatomy_items +synonym: "ubiquitous" BROAD [] +xref: CARO:0000012 +xref: UBERON:0000468 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003005 +name: female organism +def: "Gonochoristic organism that can produce female gametes." [CARO:0000028] +xref: CARO:0000028 +xref: UBERON:0003100 +is_a: XAO:0003004 ! whole organism +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003006 +name: male organism +def: "Gonochoristic organism that can produce male gametes." [CARO:0000027] +xref: CARO:0000027 +xref: UBERON:0003101 +is_a: XAO:0003004 ! whole organism +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003007 +name: anatomical entity in vitro +namespace: xenopus_anatomy_in_vitro +def: "An experimentally manipulated tissue or portion of the developing embryo, that can be culture alone (in vitro)." [XAO:curators] +is_a: XAO:0000000 ! Xenopus anatomical entity + +[Term] +id: XAO:0003008 +name: activin-induced ectoderm +namespace: xenopus_anatomy_in_vitro +def: "Ectoderm section that has been dissected from the embryo, and treated with activin, and maintained in vitro." [PMID:14061885] +is_a: XAO:0003007 ! anatomical entity in vitro + +[Term] +id: XAO:0003009 +name: disaggregated/reaggregated ectoderm treated with activin +namespace: xenopus_anatomy_in_vitro +def: "NF stage 8 ectoderm of Xenopus laevis embryos that have been cut and disaggregated. The cells have been treated with activin at a concentration to induce endodermal tissue. Afterwards the reaggregated cells have been cultured until control sibling embryos reach stage 12/13." [http://www.ncbi.nlm.nih.gov/UniGene/library.cgi?ORG=Xl&LID=1962] +is_a: XAO:0003007 ! anatomical entity in vitro + +[Term] +id: XAO:0003010 +name: aorta +def: "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs." [AAO:0010213] +xref: UBERON:0000947 +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0003011 +name: primary germ layer +def: "A layer of cells produced during the process of gastrulation during the early development of the embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The types of germ layers are the endoderm, ectoderm, and mesoderm." [BTO:0000556] +synonym: "embryonic germ layer" RELATED [] +synonym: "germ layer" RELATED [] +xref: UBERON:0000923 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003012 +name: cell +def: "Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:0000000] +xref: CARO:0000013 +xref: CL:0000000 +xref: GO:0005623 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0003013 +name: organism subdivision +def: "Anatomical structure that is a primary subdivision of the whole organism." [CARO:0000032] +synonym: "body part" RELATED [] +xref: CARO:0000032 +xref: UBERON:0000475 +is_a: XAO:0005002 ! multicellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0003014 +name: pigment cell +def: "Cell type that contains a deposition of coloring matter, the first of which differentiate during late tailbud stage, and that by NF stage 56 has produced a fully differentiated larval pigmentation pattern." [http://www.merriam-webster.com/medlineplus/pigment+cell, ISBN:0815318960] +synonym: "chromatophore" RELATED [] +xref: CL:0000147 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000319 ! trunk neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0003015 +name: myoblast +def: "Embryonic (precursor) cell of the myogenic lineage that develops from the mesoderm." [CL:0000056] +xref: CL:0000056 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003016 +name: blastomere +alt_id: XAO:0003243 +def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [CL:0000353] +synonym: "blastoderm cell" EXACT [] +xref: CL:0000353 +is_a: XAO:0003241 ! early embryonic cell +relationship: end_stage XAO:1000017 ! NF stage 7 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) + +[Term] +id: XAO:0003017 +name: fibroblast +def: "A connective tissue cell that secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057] +synonym: "keratocyte" RELATED [] +xref: CL:0000057 +is_a: XAO:0003255 ! mesodermal cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003018 +name: primary spermatogonium +def: "A germ cell that is a primordial spermatocyte in a male and that develops into secondary spermatogonia by mitotic division." [ISSN:0289-0003] +synonym: "primary spermatogonia" RELATED PLURAL [] +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0003149 ! primordial germ cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000157 ! testis +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0003019 +name: spermatocyte +def: "The developing male gamete." [XAO:curators] +xref: CL:0000017 +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0003020 ! secondary spermatogonium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0003020 +name: secondary spermatogonium +def: "A type of germ cell that results from the mitotic division of a primary spermatogonium." [ISSN:0289-0003] +synonym: "secondary spermatogonia" RELATED PLURAL [] +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0003018 ! primary spermatogonium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0003021 +name: obsolete spinal cord neuron +is_obsolete: true +replaced_by: XAO:0005018 + +[Term] +id: XAO:0003022 +name: Rohon-Beard neuron +def: "Type of neuron that is a primary mechanosensory cell, with peripheral neurites innervating the skin with free nerve endings. It first appears in trunk levels at NF stage 33/34, and at NF stage 35/36 has somas that are the largest in the spinal cord. It forms a nearly continuous double row of cells along the cord's medial dorsal surface and contributes ascending and descending axons to the dorsal tract. It appears well back in the tail by NF stage 39, begins to decline at NF stage 50 and is few in number, with pycnotic nuclei, at NF stage 55." [ISBN:0815318960, PMID:17506218] +synonym: "Rohon Beard cell" RELATED [] +xref: CL:0000247 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0003023 +name: neuron +def: "Cell that is the basic unit of nervous tissue, each consisting of a body, an axon, and dendrites, and the purpose of which is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540] +synonym: "nerve cell" RELATED [] +xref: CL:0000540 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004272 ! migrating neuroblast +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0003024 +name: head +def: "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions." [AAO:0010335] +subset: frequent_anatomy_items +subset: organism_views +xref: UBERON:0000033 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000040 ! head region +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0003025 +name: trunk +def: "Organism subdivision that is the part of the body posterior to the head and anterior to the tail." [XAO:EJS, ZFA:0001115] +subset: organism_views +xref: UBERON:0002100 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000054 ! trunk region +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003026 +name: tail +def: "Organism subdivision that is the terminal, flexible posterior appendage of the larva. It is resorbed during metamorphosis beginning with degeneration of the notochord's distal tip at NF stage 61, followed by degeneration gradually extending to its more proximal regions and reaching its proximal end by NF stage 62. By NF stage 66 it exists only as a small dorsal swelling." [http://dictionary.reference.com/medical/tail, ISBN:0471209627] +subset: organism_views +xref: UBERON:0007812 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000087 ! tail region +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003027 +name: limb +def: "Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation." [XAO:curators] +xref: UBERON:0002101 +is_a: XAO:0003013 ! organism subdivision +relationship: develops_from XAO:0003161 ! limb bud +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003028 +name: surface structure +def: "Organism subdivision that is the collection of anatomical structures on the body surface." [XAO:EJS, ZFA:0000292] +xref: UBERON:0003102 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0003029 +name: mouth +def: "Cavity in which food is initially ingested and generally contains teeth, tongue and glands." [AAO:0010355] +xref: UBERON:0000165 +is_a: XAO:0003190 ! anatomical space +relationship: develops_from XAO:0000269 ! mouth primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0003030 +name: forelimb +def: "One of the pair of limbs that are situated anteriorly, develop in sacs that separate them from the gill chamber, are well-defined buds by NF stage 48, are innervated by NF stage 51, and are ossified by NF stage 59." [BTO:0001729, ISBN:0471209627] +synonym: "anterior limb" EXACT [] +synonym: "fore limb" EXACT [] +xref: UBERON:0002102 +is_a: XAO:0003027 ! limb +relationship: develops_from XAO:0003065 ! forelimb bud +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004284 ! pectoral appendage +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003031 +name: hindlimb +def: "One of the pair of limbs that are situated posteriorly, are evident as buds laterally by NF stage 47, and are innervated by NF stage 51." [ISBN:0471209627] +synonym: "hind limb" EXACT [] +synonym: "posterior limb" EXACT [] +xref: UBERON:0002103 +is_a: XAO:0003027 ! limb +relationship: develops_from XAO:0003066 ! hindlimb bud +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004285 ! pelvic appendage +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003032 +name: digit +def: "One of several most distal parts of a limb." [UBERON:0002544] +xref: UBERON:0002544 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004265 ! autopod +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003033 +name: nostril +def: "Surface structure that provides one of the small external openings of the head that give passage to air for breathing." [http://dictionary.reference.com/medical/nostril] +xref: UBERON:0005928 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000070 ! NF stage 58 + +[Term] +id: XAO:0003034 +name: viscus +def: "An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper." [BTO:0001491] +synonym: "viscera" RELATED PLURAL [] +xref: UBERON:0002075 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003035 +name: hindlimb digit +def: "Any of the 5 digits that are the most distal parts of a hindlimb, each digit consisting of a single metatarsal, 2-4 phalanges, and a claw." [XAO:CJZ] +synonym: "hind digit" EXACT [] +synonym: "pedal digit" EXACT [] +synonym: "toe" EXACT [] +xref: UBERON:0001466 +is_a: XAO:0003032 ! digit +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003062 ! hindlimb skeleton +relationship: part_of XAO:0004300 ! foot +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003036 +name: forelimb digit +def: "Any of the 4 digits that are the most distal part of a forelimb, each digit consisting of a single metatarsal and 2-3 phalanges. Xenopus forelimb digits are numbered 2-5, with no digit number 1." [XAO:CJZ] +synonym: "fore digit" EXACT [] +synonym: "manual digit" EXACT [] +xref: UBERON:0002389 +is_a: XAO:0003032 ! digit +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003061 ! forelimb skeleton +relationship: part_of XAO:0004299 ! hand +relationship: start_stage XAO:1000068 ! NF stage 56 + +[Term] +id: XAO:0003037 +name: multi-tissue structure +def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055] +xref: CARO:0000055 +xref: UBERON:0000481 +is_a: XAO:0005002 ! multicellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0003038 +name: simple organ +def: "Multi-tissue structure that is not part of a compound organ." [CARO:0000021] +xref: CARO:0000021 +xref: UBERON:0000472 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003039 +name: compound organ component +def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019] +xref: CARO:0000019 +xref: UBERON:0000471 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003041 ! compound organ +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003040 +name: tissue +def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organization is at least partly a repetition of their short-range organization." [CARO:0000043] +synonym: "portion of tissue" EXACT [] +xref: CARO:0000043 +xref: UBERON:0000479 +is_a: XAO:0005002 ! multicellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0003041 +name: compound organ +def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024] +xref: CARO:0000024 +xref: UBERON:0003103 +is_a: XAO:0005002 ! multicellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003042 +name: embryonic structure +def: "An anatomical structure that exists only before the organism is fully formed." [BTO:0000174] +xref: UBERON:0002050 +is_a: XAO:0003000 ! anatomical structure +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000113 ! embryo +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003043 +name: primordium +def: "An embryonic structure that is the rudiment or commencement of a part or organ." [UBERON:0001048] +synonym: "primordia" RELATED PLURAL [] +xref: UBERON:0001048 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0003044 +name: endomesoderm +def: "Primary germ layer that can give rise to both mesoderm and endoderm." [XAO:curators] +synonym: "mesendoderm" RELATED [] +xref: UBERON:0000089 +is_a: XAO:0003011 ! primary germ layer +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003045 +name: epithelium +def: "Portion of tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and that is underlain by a basal lamina." [CARO:0000066] +xref: CARO:0000066 +xref: UBERON:0000483 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003046 +name: mesenchyme +def: "Portion of embryonic tissue consisting of loosely organized, undifferentiated mesodermal or neural crest derived cells, that have specific properties (they are migratory, have no polarity). Mesenchyme cells are incorporated into a wide variety of structures including connective tissue, blood, bone and cartilage as development continues." [AAO:0010427, XAO:CJZ] +synonym: "mesenchymal tissue" RELATED [] +xref: UBERON:0003104 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003047 +name: nerve +def: "Portion of tissue that consists of a fasciculated group of axons." [XAO:curators] +xref: UBERON:0001021 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003048 +name: egg +def: "A mature female germ cell that is capable of initiating formation of a new individual by fusion with a male gamete." [http://www.merriam-webster.com/medlineplus/gamete] +synonym: "ovum" RELATED [] +synonym: "unfertilized egg" RELATED [] +xref: CL:0000025 +is_a: XAO:0003150 ! gamete +relationship: develops_from XAO:0000256 ! oocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000093 ! adult frog stage + +[Term] +id: XAO:0003049 +name: adipose tissue +def: "Connective tissue in which fat is stored." [http://www.merriam-webster.com/medlineplus/adipose+tissue] +xref: UBERON:0001013 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003050 +name: fat body +def: "Anatomical structure associated with the gonads that vary in form among amphibians but are primarily composed of adipose tissue and are thought to be a source of nutrients for the gonads. A body of adipose tissue, in the form of finger-like projections, usually associated with the anterior end of the testis and ovaries. Fat bodies are suspended from the body wall by dorsal mesentry which is fused with the gonadal mesentry (the mesovarium or mesorchidium)." [AAO:0000157, ISBN:0070179778] +xref: UBERON:0003428 +is_a: XAO:0003049 ! adipose tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0003051 +name: anterior dorsal lateral plate region +def: "Region located near the pronephros and pronephric ducts that is a site of hematopoiesis in the embryo." [PMID:9618755] +synonym: "ADLPR" EXACT [] +synonym: "AGM region" RELATED [] +synonym: "aorta-gonads-mesonephros region" RELATED [] +synonym: "dorsal lateral plate region" BROAD [] +xref: UBERON:0003105 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000122 ! hematological system +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0003052 +name: oviduct +def: "A simple ciliated tube through which the ovum travels from the ovaries to the cloaca and the external environment. It is lined with mucus-secreting glands that produce the jelly that surrounds the ovum." [http://en.wikipedia.org/wiki/Oviduct] +xref: UBERON:0000993 +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000330 ! Mullerian duct +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000156 ! female genitalia +relationship: start_stage XAO:1000076 ! NF stage 64 + +[Term] +id: XAO:0003053 +name: Keller explant +namespace: xenopus_anatomy_in_vitro +def: "A rectangle of dorsal mesendoderm and ectoderm from an early-gastrula-stage Xenopus laevis embryo. It is approximately 60 deg to 90 deg wide, extending from the bottle cells to the animal pole." [ISBN:9780879695040] +is_a: XAO:0003007 ! anatomical entity in vitro + +[Term] +id: XAO:0003054 +name: stem cell +def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034] +xref: CL:0000034 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003055 +name: hematopoietic stem cell +def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, ZFA:0009014] +synonym: "HSC" EXACT [] +xref: CL:0000037 +is_a: XAO:0003054 ! stem cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000067 ! ventral blood island +relationship: part_of XAO:0003051 ! anterior dorsal lateral plate region +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0003056 +name: anterior +def: "Spatial concept denoting the front surface of the body; often used to indicate the position of one structure relative to another." [NCIt:Anterior] +subset: anatomical_site_slim +subset: sectional_anatomy_items +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0003057 +name: posterior +def: "Spatial concept denoting the back surface of the body." [NCIt:Posterior] +subset: anatomical_site_slim +subset: sectional_anatomy_items +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0003058 +name: obsolete larval structure +is_obsolete: true + +[Term] +id: XAO:0003059 +name: chondrocranium +def: "Anatomical cluster consisting of a cartilaginous skull that begins to form during early tadpole stage." [ISBN:0471209627] +synonym: "cartilaginous skull" RELATED [] +xref: UBERON:0004761 +is_a: XAO:0003075 ! cranium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003060 +name: skeletal system +def: "Anatomical system that provides physical support to the organism." [AAO:0000566] +xref: UBERON:0001434 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000168 ! musculoskeletal system +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003061 +name: forelimb skeleton +def: "The collection of all skeletal elements in a free forelimb region." [UBERON:0001440] +xref: UBERON:0001440 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003030 ! forelimb +relationship: part_of XAO:0003166 ! appendicular skeleton +relationship: start_stage XAO:1000068 ! NF stage 56 + +[Term] +id: XAO:0003062 +name: hindlimb skeleton +def: "The collection of all skeletal elements in a free hindlimb region." [XAO:EJS] +synonym: "hind limb skeleton" EXACT [] +xref: UBERON:0001441 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: part_of XAO:0003166 ! appendicular skeleton +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003063 +name: pectoral girdle +def: "Arched skeletal structure that supports the forelimbs, the rudiments of which can be distinguished in mesenchyme at NF stage 51, and is complete by NF stage 60." [http://www.merriam-webster.com/medlineplus/pectoral+girdle, ISBN:0471209627] +synonym: "shoulder girdle" RELATED [] +xref: UBERON:0007831 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003166 ! appendicular skeleton +relationship: start_stage XAO:1000063 ! NF stage 51 + +[Term] +id: XAO:0003064 +name: pelvic girdle +def: "Arched skeletal structure that supports the hindlimbs, begins to develop at NF stage 50, and is ossified by NF stage 66." [http://www.merriam-webster.com/medlineplus/pelvic+girdle, ISBN:0471209627] +synonym: "pelic skeleton" RELATED [] +synonym: "pelvis" RELATED [] +synonym: "pelvis skeleton" RELATED [] +xref: UBERON:0007832 +is_a: XAO:0004289 ! skeletal subdivision +relationship: develops_from XAO:0004493 ! pelvic girdle primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003166 ! appendicular skeleton +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003065 +name: forelimb bud +def: "The anterior limb bud that develops into the fore limb; oval shaped in dorsal aspect by NF stage 50, and paddle shaped by NF stage 53; all four fingers and melanophores apparent by NF stage 54." [XAO:curators] +xref: UBERON:0005417 +is_a: XAO:0003161 ! limb bud +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0003066 +name: hindlimb bud +def: "The posterior limb bud that develops into the hindlimb; a thickening of the ectoderm first noticeable at NF stage 47, innervated by NF stage 51. The hindlimb buds develop before the forelimb buds." [XAO:curators] +synonym: "hind limb bud" EXACT [] +xref: UBERON:0005418 +is_a: XAO:0003161 ! limb bud +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0003067 +name: obsolete fore epipodium +is_obsolete: true +replaced_by: XAO:0004297 + +[Term] +id: XAO:0003068 +name: obsolete fore mesopodium +is_obsolete: true +replaced_by: XAO:0003207 + +[Term] +id: XAO:0003069 +name: obsolete hind propodium +is_obsolete: true +replaced_by: XAO:0004296 + +[Term] +id: XAO:0003070 +name: obsolete hind metapodium +is_obsolete: true +replaced_by: XAO:0003212 + +[Term] +id: XAO:0003071 +name: obsolete fore propodium +is_obsolete: true +replaced_by: XAO:0004295 + +[Term] +id: XAO:0003072 +name: obsolete hind epipodium +is_obsolete: true +replaced_by: XAO:0004298 + +[Term] +id: XAO:0003073 +name: postcranial axial skeleton +def: "Skeletal structure that has as its parts the vertebral column, located in the dorsal part of the trunk, and is formed by a series of vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord." [AAO:0000034] +xref: UBERON:0002090 +is_a: XAO:0004289 ! skeletal subdivision +relationship: develops_from XAO:0000401 ! sclerotomal cartilage +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004011 ! axial skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003074 +name: vertebral column +def: "Anatomical cluster that consists of all the vertebrae in the body." [VSAO:0000185] +synonym: "spine" RELATED [] +xref: UBERON:0001130 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003073 ! postcranial axial skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003075 +name: cranium +def: "Skeletal system that is part of the head, including the splanchnocranium, chondrocranium, and dermatocranium." [XAO:curators] +synonym: "cranial skeleton" RELATED [] +xref: UBERON:0010323 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: part_of XAO:0003060 ! skeletal system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003076 +name: cervical vertebra +def: "The first vertebra, which arises from the trunk somites 1 and 2." [XAO:CJZ] +synonym: "atlas vertebra" EXACT [] +synonym: "first vertebra" EXACT [] +synonym: "first vertebrae" RELATED PLURAL [] +xref: UBERON:0002413 +is_a: XAO:0004019 ! vertebra +relationship: develops_from XAO:0000406 ! trunk somite 1 +relationship: develops_from XAO:0000407 ! trunk somite 2 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003077 +name: presacral vertebra +def: "The vertebra anterior to the sacral vetebra." [XAO:CJZ] +synonym: "presacral vertebrae" RELATED PLURAL [] +xref: UBERON:0004451 +is_a: XAO:0004019 ! vertebra +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0003078 +name: sacral vertebra +def: "The 9th vertebra, which arises from the trunk somites 9 and 10. It joins the illia laterally at NF stage 60 and later coalesces with the urostyle in the midline of the pelvic girdle to form a single unit in the adult frog." [PMID:15679868, XAO:CJZ] +synonym: "ninth vertebra" EXACT [] +synonym: "ninth vertebrae" RELATED PLURAL [] +synonym: "sacral vertebrae" RELATED PLURAL [] +xref: UBERON:0001094 +is_a: XAO:0004019 ! vertebra +relationship: develops_from XAO:0000417 ! trunk somite 9 +relationship: develops_from XAO:0000418 ! trunk somite 10 +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0003079 +name: caudal vertebra +def: "The bones that make up the tail region of the tadpole." [XAO:curators] +synonym: "caudal vertebrae" RELATED PLURAL [] +synonym: "postsacral vertebra" RELATED [] +xref: UBERON:0001095 +is_a: XAO:0004019 ! vertebra +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003064 ! pelvic girdle +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003080 +name: urostyle +def: "Skeletal element in the midline of the pelvic girdle that arises from somites 10-13. It is a rodlike caudal bony structure unique to anurans that lies within a compartment formed by the elongated, anteriorly oriented pelvic girdle. It is formed by the fusion of the neural arches of the 10th-13th vertebrae, and the posterior-most remnants of the hypochord. Timing of complete ossification varies between NF stages 62 and 66." [AAO:0000732, PMID:15679868, XAO:CJZ] +xref: UBERON:0003106 +is_a: XAO:0004276 ! bone element +relationship: develops_from XAO:0000056 ! hypochord +relationship: develops_from XAO:0000418 ! trunk somite 10 +relationship: develops_from XAO:0000419 ! trunk somite 11 +relationship: develops_from XAO:0000420 ! trunk somite 12 +relationship: develops_from XAO:0000421 ! trunk somite 13 +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003073 ! postcranial axial skeleton +relationship: start_stage XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:0003081 +name: larynx +def: "Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located." [AAO:0000268] +xref: UBERON:0001737 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000117 ! respiratory system +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0003082 +name: obsolete sucker +is_obsolete: true +consider: XAO:0000033 + +[Term] +id: XAO:0003083 +name: braincase and otic capsule skeleton +def: "Skeleton encasing the brain and auditory apparatus." [ISBN:0070179778] +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0003084 +name: lower jaw +def: "Anatomical cluster consisting of the ventral portion of the first pharyngeal arch." [TAO:0001273, XAO:EJS] +synonym: "ventral mandibular arch" RELATED [] +xref: UBERON:0003278 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003085 +name: Meckel's cartilage +def: "Paired cartilaginous component of the lower jaw that fuses together through a median inferior labial cartilage, resulting in a single curved bar of cartilage by metamorphic climax. During metamorphosis it is surrounded by the developing dentale and goniale." [PMID:3693112] +synonym: "cm" EXACT [] +xref: UBERON:0003107 +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0000024 ! mandibular crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000097 ! mandibular arch +relationship: part_of XAO:0003084 ! lower jaw +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0003086 +name: suspensorium +def: "Anatomical cluster consisting of the mandibular structures which connect the base of the lower jaw with the skull." [http://medical-dictionary.thefreedictionary.com/Suspensorium] +xref: UBERON:0003108 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003176 ! splanchnocranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003087 +name: upper jaw +def: "The dorsal portion of the first pharyngeal arch." [TAO:0001272, XAO:EJS] +synonym: "palatoquadrate arch" RELATED [] +xref: UBERON:0003277 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003088 +name: seminiferous tubule +def: "Any of the coiled tubules located in the testes in which spermatozoa are produced." [AAO:0010399] +xref: UBERON:0001343 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000157 ! testis +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003090 +name: oculomotor nerve +def: "Cranial nerve that largely consists of somatic efferent fibers which innervate four eye muscles (m rectus superior, m obliquus inferior, and mm rectus inferior and anterior)." [ISBN:080184780X] +synonym: "cranial nerve III" EXACT [] +synonym: "oculomotorius" EXACT [] +xref: UBERON:0001643 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0003091 +name: trochlear nerve +def: "Somatic efferent nerve that runs to the superior oblique muscle of the eye." [ISBN:080184780X] +synonym: "cranial nerve IV" EXACT [] +synonym: "pathetic nerve" EXACT [] +synonym: "trochlearis" EXACT [] +xref: UBERON:0001644 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0003092 +name: trigeminal nerve +def: "Cranial nerve that has three branches: the ophthalmic branch that supplies the skin of the nose and upper jaw, and the maxillary and mandibular branches that supply the lower jaw." [UBERON:0001645] +synonym: "cranial nerve V" EXACT [] +synonym: "trigeminus" EXACT [] +xref: UBERON:0001645 +is_a: XAO:0000429 ! cranial nerve +relationship: develops_from XAO:0004092 ! preplacodal ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003093 +name: abducens nerve +def: "Cranial nerve that runs to the eye muscles." [UBERON:0001646] +synonym: "abducens" EXACT [] +synonym: "abducent nerve" EXACT [] +synonym: "cranial nerve VI" EXACT [] +xref: UBERON:0001646 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000061 ! NF stage 49 + +[Term] +id: XAO:0003094 +name: facial nerve +def: "Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches)." [ISBN:0471209627] +synonym: "cranial nerve VII" EXACT [] +synonym: "facialis" EXACT [] +xref: UBERON:0001647 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003197 ! gustatory system +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0003095 +name: vestibulocochlear nerve +def: "Cranial nerve that runs to the ear. It has two branches, the cochlear nerve and the vestibular nerve, which receives positional information." [XAO:curators] +synonym: "auditory nerve" RELATED [] +synonym: "cranial nerve VIII" EXACT [] +synonym: "stato-acoustic nerve" EXACT [] +xref: UBERON:0001648 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003195 ! vestibuloauditory system +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0003096 +name: glossopharyngeal nerve +def: "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." [ISBN:0471209627] +synonym: "cranial nerve IX" EXACT [] +xref: UBERON:0001649 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003197 ! gustatory system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003097 +name: vagus nerve +def: "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." [ISBN:0471209627] +synonym: "cranial nerve X" EXACT [] +synonym: "vagal nerve" RELATED [] +synonym: "vagus afferents" RELATED [] +xref: UBERON:0001759 +is_a: XAO:0000429 ! cranial nerve +relationship: develops_from XAO:0000284 ! epibranchial placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003197 ! gustatory system +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0003098 +name: cerebellum +def: "A dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum." [UBERON:0002037] +xref: UBERON:0002037 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003099 +name: fourth ventricle +def: "Irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space." [UBERON:0002422] +synonym: "4th ventricle" EXACT [] +synonym: "IVth ventricle" EXACT [] +xref: UBERON:0002422 +is_a: XAO:0004602 ! brain ventricle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003100 +name: medulla oblongata +def: "Posterior portion of the hindbrain that controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses." [AAO:0010486] +xref: UBERON:0001896 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003101 +name: spinal nerve +def: "A mixed nerve that carries motor, sensory, and autonomic signals between the spinal cord and the body." [http://en.wikipedia.org/wiki/Spinal_nerve] +xref: UBERON:0001780 +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003102 +name: transverse process +def: "Any of the projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae." [AAO:0000698] +xref: UBERON:0001077 +is_a: XAO:0004020 ! process +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004019 ! vertebra +relationship: start_stage XAO:1000073 ! NF stage 61 + +[Term] +id: XAO:0003103 +name: claw +def: "Anatomical structure consisting of a small, pointed keratinized appendage at the end of each of the three inner toes of the hindlimbs." [XAO:curators] +xref: UBERON:0001705 +is_a: XAO:0003162 ! acellular anatomical structure +relationship: develops_from XAO:0004416 ! claw primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003035 ! hindlimb digit +relationship: start_stage XAO:1000070 ! NF stage 58 + +[Term] +id: XAO:0003104 +name: myotome of head somite 1 +def: "Compartment of head somite 1 that is a precursor of muscle." [XAO:EJS] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000396 ! head somite 1 +relationship: end_stage XAO:1000042 ! NF stage 26 +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0003105 +name: myotome of head somite 2 +def: "Compartment of head somite 2 that is a precursor of muscle." [XAO:EJS] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000403 ! head somite 2 +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003106 +name: myotome of head somite 3 +def: "Compartment of head somite 3 that is a precursor of muscle." [XAO:EJS] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000404 ! head somite 3 +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003107 +name: myotome of head somite 4 +def: "Compartment of head somite 4 that is a precursor of muscle." [XAO:EJS] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000405 ! head somite 4 +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003108 +name: myotome of trunk somite 1 +def: "Compartment of trunk somite 1 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 1" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000406 ! trunk somite 1 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003109 +name: myotome of trunk somite 2 +def: "Compartment of trunk somite 2 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 2" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000407 ! trunk somite 2 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003110 +name: myotome of trunk somite 3 +def: "Compartment of trunk somite 3 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 3" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000408 ! trunk somite 3 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0003111 +name: myotome of trunk somite 4 +def: "Compartment of trunk somite 4 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 4" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000409 ! trunk somite 4 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003112 +name: sclerotome of head somite 4 +def: "Compartment of head somite 4 that is a precursor of the axial skeleton." [XAO:EJS] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000405 ! head somite 4 +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003113 +name: sclerotome of trunk somite 1 +def: "Compartment of trunk somite 1 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 1" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000406 ! trunk somite 1 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003114 +name: sclerotome of trunk somite 2 +def: "Compartment of trunk somite 2 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 2" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000407 ! trunk somite 2 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0003115 +name: sclerotome of trunk somite 3 +def: "Compartment of trunk somite 3 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 3" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000408 ! trunk somite 3 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0003116 +name: sclerotome of trunk somite 4 +def: "Compartment of trunk somite 4 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 4" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000409 ! trunk somite 4 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003117 +name: myotome of trunk somite 5 +def: "Compartment of trunk somite 5 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 5" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000410 ! trunk somite 5 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003118 +name: myotome of trunk somite 6 +def: "Compartment of trunk somite 6 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 6" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000411 ! trunk somite 6 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003119 +name: myotome of trunk somite 7 +def: "Compartment of trunk somite 7 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 7" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000412 ! trunk somite 7 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003120 +name: myotome of trunk somite 8 +def: "Compartment of trunk somite 8 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 8" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000416 ! trunk somite 8 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003121 +name: sclerotome of trunk somite 5 +def: "Compartment of trunk somite 5 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 5" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000410 ! trunk somite 5 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003122 +name: sclerotome of trunk somite 6 +def: "Compartment of trunk somite 6 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 6" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000411 ! trunk somite 6 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0003123 +name: sclerotome of trunk somite 7 +def: "Compartment of trunk somite 7 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 7" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000412 ! trunk somite 7 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003124 +name: sclerotome of trunk somite 8 +def: "Compartment of trunk somite 8 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 8" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000416 ! trunk somite 8 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003125 +name: myotome of trunk somite 9 +def: "Compartment of trunk somite 9 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 9" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000417 ! trunk somite 9 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003126 +name: sclerotome of trunk somite 9 +def: "Compartment of trunk somite 9 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 9" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000417 ! trunk somite 9 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003127 +name: sclerotome of trunk somite 10 +def: "Compartment of trunk somite 10 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 10" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000418 ! trunk somite 10 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003128 +name: myotome of trunk somite 10 +def: "Compartment of trunk somite 10 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 10" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000418 ! trunk somite 10 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003129 +name: sclerotome of trunk somite 11 +def: "Compartment of trunk somite 11 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 11" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000419 ! trunk somite 11 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003130 +name: myotome of trunk somite 11 +def: "Compartment of trunk somite 11 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 11" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000419 ! trunk somite 11 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003131 +name: sclerotome of trunk somite 12 +def: "Compartment of trunk somite 12 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 12" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000420 ! trunk somite 12 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0003132 +name: myotome of trunk somite 12 +def: "Compartment of trunk somite 12 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 12" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000420 ! trunk somite 12 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0003133 +name: sclerotome of trunk somite 13 +def: "Compartment of trunk somite 13 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 13" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000421 ! trunk somite 13 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003134 +name: myotome of trunk somite 13 +def: "Compartment of trunk somite 13 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 13" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000421 ! trunk somite 13 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003135 +name: sclerotome of tail somite 14 +def: "Compartment of tail somite 14 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 14" EXACT [] +synonym: "sclerotome of trunk somite 14" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000422 ! tail somite 14 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003136 +name: myotome of tail somite 14 +def: "Compartment of tail somite 14 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 14" EXACT [] +synonym: "myotome of trunk somite 14" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000422 ! tail somite 14 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003137 +name: sclerotome of tail somite 15 +def: "Compartment of tail somite 15 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 15" EXACT [] +synonym: "sclerotome of trunk somite 15" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000423 ! tail somite 15 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0003138 +name: myotome of tail somite 15 +def: "Compartment of tail somite 15 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 15" EXACT [] +synonym: "myotome of trunk somite 15" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000423 ! tail somite 15 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0003139 +name: sclerotome of tail somite 16 +def: "Compartment of tail somite 16 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 16" EXACT [] +synonym: "sclerotome of trunk somite 16" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000424 ! tail somite 16 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003140 +name: myotome of tail somite 16 +def: "Compartment of tail somite 16 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 16" EXACT [] +synonym: "myotome of trunk somite 16" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000424 ! tail somite 16 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003141 +name: sclerotome of tail somite 17 +def: "Compartment of tail somite 17 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 17" EXACT [] +synonym: "sclerotome of trunk somite 17" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0000425 ! tail somite 17 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003142 +name: myotome of tail somite 17 +def: "Compartment of tail somite 17 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of somite 17" EXACT [] +synonym: "myotome of trunk somite 17" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0000425 ! tail somite 17 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003143 +name: tail somite +def: "Any of the somites that form posterior to the trunk and are resorbed at metamorphosis." [XAO:EJS] +xref: UBERON:0009621 +is_a: XAO:0000058 ! somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003144 +name: amphibian papilla +def: "The principal auditory organ of the frog, which utilizes both mechanical and electrical (hair cell-based) frequency tuning mechanisms for hearing, located near the junction of the utricle and the saccule bones of the inner ear." [PMID:10377339] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0003145 +name: basilar papilla +def: "A sensory structure in the lagenar portion of an amphibian's membranous labyrinth between the oval and round windows." [XAO:curators] +synonym: "papilla basilaris" EXACT [] +xref: UBERON:0002227 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:0003146 +name: gonad +def: "Anatomical structure that produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins. Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [AAO:0000213, ZFA:0000413] +xref: UBERON:0000991 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:0003147 +name: spermatozoon +def: "A mature male germ cell that develops from a spermatid." [CL:0000019] +synonym: "sperm" RELATED [] +synonym: "spermatozoa" RELATED PLURAL [] +xref: CL:0000019 +is_a: XAO:0003150 ! gamete +relationship: develops_from XAO:0003151 ! spermatid +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000093 ! adult frog stage + +[Term] +id: XAO:0003148 +name: obsolete germ line cell +is_obsolete: true +replaced_by: XAO:0000111 + +[Term] +id: XAO:0003149 +name: primordial germ cell +def: "Cell that arises from the endodermal germ plasm and can be detected by NF stage 28 in the endodermal mass. At NF stages 42-47, PGCs migrate to the two genital ridges, which are the first rudiments of the gonads. By NF stage 50, the PGCs begin to loose their yolky material. In males, starting at NF stage 52, PGCs migrate from the genital ridge cortical region into the medullary tissue, where they will form primary spermatogonia at sexual maturity. In females, the medullary tissue remains free of PGCs; they instead embed in the cortical region and multiply to form primary oogonia, which will mature into ova at sexual maturity." [ISBN:0815318960, XAO:curators] +synonym: "PGC" EXACT [] +synonym: "primitive germ cell" RELATED [] +xref: CL:0000670 +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0000090 ! endoderm +relationship: develops_from XAO:0000233 ! germ plasm +relationship: end_stage XAO:1000070 ! NF stage 58 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0003150 +name: gamete +def: "A mature male or female germ cell." [http://www.merriam-webster.com/medlineplus/gamete] +xref: CL:0000300 +is_a: XAO:0000111 ! germ cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000142 ! genital system +relationship: start_stage XAO:1000093 ! adult frog stage + +[Term] +id: XAO:0003151 +name: spermatid +def: "Male germ cell that is derived from spermatocytes and develops into spermatozoa." [NCIt:Spermatid] +xref: CL:0000018 +is_a: XAO:0000111 ! germ cell +relationship: develops_from XAO:0003019 ! spermatocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:0003152 +name: immune system +def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [http://www.merriam-webster.com/medlineplus/immune+system] +xref: UBERON:0002405 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003153 +name: larval immune system +def: "The immune system of a postembryonic, hatched or immature tadpole, prior to metamorphosis." [XAO:curators] +is_a: XAO:0003152 ! immune system +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003154 +name: adult immune system +def: "The complete system of biological structures and processes within the adult organism that protects against disease by identifying and killing pathogens and tumor cells." [XAO:curators] +is_a: XAO:0003152 ! immune system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000093 ! adult frog stage + +[Term] +id: XAO:0003155 +name: lymphocyte +def: "A cell of the B cell, T cell, or natural killer cell lineage." [CL:0000542] +xref: CL:0000542 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0005323 ! lymphoblast +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003156 +name: natural killer cell +def: "A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells." [CL:0000623] +synonym: "natural killer T cell" RELATED [] +synonym: "NK cell" RELATED [] +xref: CL:0000623 +is_a: XAO:0003157 ! T cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003157 +name: T cell +def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [AAO:0010311] +xref: CL:0000084 +is_a: XAO:0003155 ! lymphocyte +relationship: develops_from XAO:0003159 ! thymocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003158 +name: B cell +def: "One of the two types of lymphocytes (the others being T cells). All lymphocytes begin their development in the bone marrow. B cells are involved in so-called humoral immunity." [XAO:curators] +xref: CL:0000236 +is_a: XAO:0003155 ! lymphocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003159 +name: thymocyte +def: "An immature T cell located in the thymus." [AAO:0010312] +is_a: XAO:0003155 ! lymphocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000163 ! thymus +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003160 +name: anatomical cluster +def: "Anatomical group that has its parts adjacent to one another." [CARO:0000041] +xref: CARO:0000041 +xref: UBERON:0000477 +is_a: XAO:0003001 ! anatomical group +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003161 +name: limb bud +def: "Structure that is an early outgrowth of a presumptive limb." [AAO:0010375] +xref: UBERON:0004347 +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0003162 +name: acellular anatomical structure +def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [CARO:0000040] +synonym: "acellular structure" EXACT [] +xref: CARO:0000040 +xref: UBERON:0000476 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0003163 +name: basal lamina +def: "Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue." [CARO:0000065] +synonym: "basement lamina" BROAD [] +xref: CARO:0000065 +xref: UBERON:0000482 +is_a: XAO:0003162 ! acellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003045 ! epithelium +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0003164 +name: solid compound organ +def: "Compound organ that does not contain macroscopic anatomical spaces." [CARO:0000074] +xref: CARO:0000074 +xref: UBERON:0000491 +is_a: XAO:0003041 ! compound organ +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003165 +name: cavitated compound organ +def: "Compound organ that contains one or more macroscopic anatomical spaces." [CARO:0000072] +xref: CARO:0000072 +xref: UBERON:0000489 +is_a: XAO:0003041 ! compound organ +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:0003166 +name: appendicular skeleton +def: "Skeletal structure that has as its parts the pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hindlimbs." [AAO:0000747] +xref: UBERON:0002091 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003167 +name: obsolete fore metapodium +is_obsolete: true +replaced_by: XAO:0003208 + +[Term] +id: XAO:0003168 +name: obsolete hind mesopodium +is_obsolete: true +replaced_by: XAO:0003211 + +[Term] +id: XAO:0003169 +name: dermatocranium +def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton." [UBERON:0003113] +xref: UBERON:0003113 +is_a: XAO:0003075 ! cranium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003170 +name: neurocranium +def: "Anatomical cluster that consists of the cartilages and bones that surround the brain." [TAO:0001580, XAO:EJS] +xref: UBERON:0001703 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003171 +name: orbital region +def: "An anatomical cluster that is part of the cranium and structurally supports the eye." [AAO:0010220] +xref: UBERON:0001697 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003172 +name: olfactory region +def: "Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs." [AAO:0010206] +xref: UBERON:0003112 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003173 +name: occipital region +def: "An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles." [AAO:0010199] +xref: UBERON:0005902 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003174 +name: sphenoid region +def: "Anatomical cluster that forms the floor and side walls of the middle part of the cranium." [UBERON:0003111] +xref: UBERON:0003111 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0003175 +name: otic region +def: "Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system." [AAO:0010208] +xref: UBERON:0003110 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0003176 +name: splanchnocranium +def: "Regional skeletal system of the jaws, hyoid and branchial arches." [XAO:EJS, ZFA:0001216] +xref: UBERON:0008895 +is_a: XAO:0003075 ! cranium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0003177 +name: hyoid arch skeleton +def: "Skeletal subdivision comprising the skeletal elements of the hyoid arch." [XAO:EJS] +xref: UBERON:0005884 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000098 ! hyoid arch +relationship: part_of XAO:0003176 ! splanchnocranium +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003178 +name: dorsal hyoid arch skeleton +def: "Skeletal subdivision comprising the dorsal skeletal elements of the hyoid arch." [XAO:EJS] +xref: UBERON:0011152 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003177 ! hyoid arch skeleton +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003179 +name: ventral hyoid arch skeleton +def: "Skeletal subdivision comprising the ventral skeletal elements of the hyoid arch." [XAO:EJS] +xref: UBERON:0011153 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003177 ! hyoid arch skeleton +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0003180 +name: branchial arch skeleton +def: "Skeletal and cartilaginous elements of the branchial arches; the last five of the set of seven pharyngeal arches; generally branchial arch no. 1 is the first branchial arch, or the third pharyngeal arch, but some authors do not follow this convention." [PMID:8589427] +synonym: "gill arch skeleton" RELATED [] +synonym: "pharyngeal arch skeleton 3-7" RELATED [] +synonym: "visceral arch skeleton" RELATED [] +xref: UBERON:0005886 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000099 ! branchial arch +relationship: part_of XAO:0003176 ! splanchnocranium +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0003181 +name: branchial arch skeleton 1 +def: "Skeletal and cartilaginous elements of the first branchial or pharyngeal arch." [XAO:curators] +is_a: XAO:0003180 ! branchial arch skeleton +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000447 ! branchial arch 1 +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0003182 +name: branchial arch skeleton 2 +def: "Skeletal and cartilaginous elements of the second branchial or pharyngeal arch." [XAO:curators] +is_a: XAO:0003180 ! branchial arch skeleton +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000449 ! branchial arch 2 +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0003183 +name: branchial arch skeleton 3 +def: "Skeletal and cartilaginous elements of the third branchial or pharyngeal arch." [XAO:curators] +is_a: XAO:0003180 ! branchial arch skeleton +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000451 ! branchial arch 3 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0003184 +name: branchial arch skeleton 4 +def: "Skeletal and cartilaginous elements of the fourth branchial or pharyngeal arch." [XAO:curators] +is_a: XAO:0003180 ! branchial arch skeleton +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000453 ! branchial arch 4 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0003185 +name: anatomical direction +def: "Any spatial descriptor that describes the orientation of the anatomical features of an embryo." [XAO:curators] +is_a: XAO:0000000 ! Xenopus anatomical entity + +[Term] +id: XAO:0003186 +name: anatomical region +def: "A region of the whole organism that contains a recognizable set of structures or anatomical entities." [XAO:curators] +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0003187 +name: medial +def: "Spatial concept pertaining to being toward the middle or inside." [NCIt:Medial] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0003188 +name: proximal +def: "Spatial concept denoting a part of the body that is closer to the center of the body than another part." [NCIt:Proximal] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0003189 +name: distal +def: "Spatial concept denoting a part of the body that is farther away from the center of the body than another part." [NCIt:Distal] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction + +[Term] +id: XAO:0003190 +name: anatomical space +def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [CARO:0000005] +xref: CARO:0000005 +xref: UBERON:0000464 +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:0003191 +name: left atrium +def: "The chamber of the heart that receives blood from the lungs." [XAO:EJS] +xref: UBERON:0002079 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005198 ! cardiac atrium +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0003192 +name: right atrium +def: "The chamber of the heart that receives blood from the sinus venosus." [XAO:EJS] +xref: UBERON:0002078 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005198 ! cardiac atrium +relationship: start_stage XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:0003193 +name: cardiac ventricle +def: "Cardiac chamber that consists of a wall that surrounds the cavity of a ventricle. The amphibian heart has a single ventricle and an outflow tract with an incomplete spiral septum." [UBERON:0002082] +xref: UBERON:0002082 +is_a: XAO:0003165 ! cavitated compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0003194 +name: sensory system +def: "Part of the nervous system responsible for processing sensory information." [http://en.wikipedia.org/wiki/Sensory_system] +xref: UBERON:0001032 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003195 +name: vestibuloauditory system +def: "The sensory system used for balance and hearing." [XAO:curators] +xref: UBERON:0002105 +is_a: XAO:0003194 ! sensory system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0003196 +name: olfactory system +def: "The sensory system used for olfaction (the sense of smell)." [http://en.wikipedia.org/wiki/Olfactory_system] +xref: UBERON:0005725 +is_a: XAO:0003194 ! sensory system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0003197 +name: gustatory system +def: "The sensory system used for the sense of taste." [http://en.wikipedia.org/wiki/Gustatory_system] +xref: UBERON:0001033 +is_a: XAO:0003194 ! sensory system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0003198 +name: visual system +def: "The sensory system used for sight." [XAO:curators] +xref: UBERON:0002104 +is_a: XAO:0003194 ! sensory system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0003199 +name: lymphatic system +def: "Part of the circulatory system that consists of a series of vessels that collect blood (exclusive of erythrocytes) which seeps through capillary walls and return it to the veins. The lymphatic system of vasculature drains lymph fluid from the tissue spaces of most organs and returns it to the blood vasculature for recirculation. The lymphatic sytem functions in immune responses. Anurans generate a lot of lymphatic fluid, largely as a consequence of their very leaky vasculature and high interstitial compliance. Lymph is ultimately pumped into the venous system by paired, dorsally located lymph hearts. Hedrick et al (2007) showed that lung inflation and deflation assists lymph movement. Lymph is moved during lung deflation to the subvertebral sac from anterior and posterior lymph sacs. During lung inflation, increased lymph sac pressure moves lymph to axillary regions, where lymph hearts can return lymph to the vascular space." [AAO:0010522, PMID:17981861, XAO:curators] +xref: UBERON:0002465 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0003200 +name: gut epithelium +def: "The epithelium of the gut." [XAO:curators] +xref: UBERON:0003929 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0003201 +name: oral epithelium +def: "Epithelium that lines the oral cavity, with many short microvilli as well as mucous cells, rodlet cells and taste buds." [UBERON:0002424] +xref: UBERON:0002424 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003029 ! mouth +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0003202 +name: pharyngeal epithelium +def: "Epithelium lining the pharynx, consisting largely of simple columnar epithelium." [TAO:0001174, XAO:EJS] +xref: UBERON:0003351 +is_a: XAO:0004007 ! unilaminar epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:0003203 +name: dental epithelium +def: "Epithelium that is part of a developing tooth or dental organ." [XAO:EJS, ZFA:0005134] +xref: UBERON:0003843 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 + +[Term] +id: XAO:0003204 +name: neural tube +def: "Hollow epithelial tube on the dorsal side of the embryo that develops into the brain and spinal cord." [AAO:0010617] +xref: UBERON:0001049 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: develops_from XAO:0000248 ! neural groove +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000215 ! central nervous system +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0003205 +name: chondrocyte +def: "Polymorphic cell type that forms cartilage." [CL:0000138] +synonym: "cartilage cell" RELATED [] +xref: CL:0000138 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0003238 ! chondroblast +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000170 ! cartilage tissue +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0003206 +name: podocyte +def: "Cell type that is a component of the glomus." [XAO:curators] +synonym: "podocytes" RELATED PLURAL [] +xref: CL:0000653 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0000318 ! glomus +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0003207 +name: carpus +def: "The cluster of bones in the wrist between the radius, ulna and metacarpus, they do not belong to individual fingers, but allow the wrist to move and rotate." [ISBN:0070179778] +xref: UBERON:0009880 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003061 ! forelimb skeleton +relationship: part_of XAO:0004299 ! hand +relationship: start_stage XAO:1000069 ! NF stage 57 + +[Term] +id: XAO:0003208 +name: metacarpus +def: "Each of the bones forming the part of the hand between the fingers and the wrist." [http://www.infovisual.info/02/028_en.html] +xref: UBERON:0010544 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003061 ! forelimb skeleton +relationship: part_of XAO:0004299 ! hand +relationship: start_stage XAO:1000069 ! NF stage 57 + +[Term] +id: XAO:0003209 +name: radio-ulna +def: "Either of the paired, long bones of endochondral origin formed by the fusion of the radius and ulna." [AAO:0000901] +synonym: "radioulna" EXACT [] +synonym: "radius-ulna" EXACT [] +xref: UBERON:0006715 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003061 ! forelimb skeleton +relationship: part_of XAO:0004297 ! forelimb zeugopod +relationship: start_stage XAO:1000068 ! NF stage 56 + +[Term] +id: XAO:0003210 +name: humerus +def: "Either of the paired, elongate, cylindrical forelimb bones of endochondral origin that extend from the pectoral girdle (shoulders) to the elbows." [AAO:0000679, XAO:curators] +xref: UBERON:0000976 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003061 ! forelimb skeleton +relationship: part_of XAO:0004295 ! forelimb stylopod +relationship: start_stage XAO:1000068 ! NF stage 56 + +[Term] +id: XAO:0003211 +name: tarsus +def: "A bone of the wrist of the hindlimb, which remains cartilaginous until NF stage 66." [ISBN:0815318960] +synonym: "tarsalia" EXACT [] +xref: UBERON:0009879 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003062 ! hindlimb skeleton +relationship: part_of XAO:0004300 ! foot +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003212 +name: metatarsus +def: "Each of the bones forming the part of the foot between the toes and the heel." [http://www.infovisual.info/02/028_en.html] +xref: UBERON:0010545 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003062 ! hindlimb skeleton +relationship: part_of XAO:0004300 ! foot +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003213 +name: tibia-fibula +def: "Bone of the lower hind leg, which undergoes ossification from NF stage 56 to stage 66." [ISBN:0471209627] +synonym: "tibiofibula" EXACT [] +xref: UBERON:0006714 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003062 ! hindlimb skeleton +relationship: part_of XAO:0004298 ! hindlimb zeugopod +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003214 +name: femur +def: "Either of the paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees. Proximal bone of the hind leg, which begins to ossify at NF stage 55." [ISBN:0471209627] +xref: UBERON:0000981 +is_a: XAO:0004018 ! endochondral bone +relationship: develops_from XAO:0004238 ! femur rudiment +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003062 ! hindlimb skeleton +relationship: part_of XAO:0004296 ! hindlimb stylopod +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0003215 +name: photoreceptor layer +def: "The layer within the retina where the photoreceptor cell receptor segments reside." [XAO:EJS, ZFA:0000143] +synonym: "retinal photoreceptor layer" RELATED [] +xref: UBERON:0001787 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:17Z + +[Term] +id: XAO:0003216 +name: retinal neural layer +def: "The layer of nerve cells in the retina." [XAO:curators] +synonym: "neural retina" RELATED [] +xref: UBERON:0003902 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000266 ! retinal layer +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2009-07-15T02:02:33Z + +[Term] +id: XAO:0003217 +name: retinal pigmented epithelium +def: "The monolayer of pigmented epithelium covering the neural retina." [XAO:EJS, ZFA:0000144] +synonym: "pigmented epithelium" RELATED [] +synonym: "pigmented retinal epithelium" RELATED [] +synonym: "RPE" EXACT [] +xref: UBERON:0001782 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2009-07-15T02:05:18Z + +[Term] +id: XAO:0003218 +name: retinal outer plexiform layer +def: "The layer within the retina where the bipolar cells synapse with the photoreceptor cells." [UBERON:0001790] +xref: UBERON:0001790 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:28Z + +[Term] +id: XAO:0003219 +name: retinal outer nuclear layer +def: "The layer within the retina where the photoreceptor cell bodies reside." [UBERON:0001789] +xref: UBERON:0001789 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:30Z + +[Term] +id: XAO:0003220 +name: optic fiber layer +def: "Fiber layer adjacent the retinal ganglion cell layer that comprises its axons as they traverse to the optic nerve." [XAO:EJS, ZFA:0001619] +xref: UBERON:0001793 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:32Z + +[Term] +id: XAO:0003221 +name: retinal inner nuclear layer +def: "The layer of the retina composed of the cell bodies of bipolar cells, horizontal cells, and some of the cell bodies of amacrine cells." [UBERON:0001791] +xref: UBERON:0001791 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:34Z + +[Term] +id: XAO:0003222 +name: inner limiting membrane +def: "Retinal layer composed of the basal lamina of Muller cells." [NCIt:Inner_Limiting_Membrane] +xref: UBERON:0001794 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:37Z + +[Term] +id: XAO:0003223 +name: retinal ganglion cell layer +def: "Innermost nuclear layer of the retina, consisting of retinal ganglion cells, containing neurons that project axons through the optic nerve to the brain." [UBERON:0001792] +xref: UBERON:0001792 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:41Z + +[Term] +id: XAO:0003224 +name: outer limiting membrane +def: "A thin fenestrated layer of the pars nervosa retinae adjacent to the outer nuclear layer and through which extend the visual rods and cones." [NCIt:Outer_Limiting_Membrane] +xref: UBERON:0001788 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:44Z + +[Term] +id: XAO:0003225 +name: retinal inner plexiform layer +def: "The plexiform layer of the retina positioned between the inner nuclear layer and the ganglion cell layer and containing the dendrites of retinal ganglion cells and processes of bipolar and amacrine cells." [UBERON:0001795] +xref: UBERON:0001795 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2009-07-15T02:26:47Z + +[Term] +id: XAO:0003226 +name: optic tectum +def: "Structure that is the anterodorsal-most region of the midbrain and is responsible for auditory and visual reflexes." [XAO:curators] +synonym: "midbrain tectum" RELATED [] +synonym: "OT" EXACT [] +synonym: "tectum" RELATED [] +synonym: "tectum opticum" RELATED [] +xref: UBERON:0001945 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000014 ! midbrain +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-15T03:37:08Z + +[Term] +id: XAO:0003227 +name: pharynx +def: "Anatomical cavity bounded by the derivatives of the branchial arches." [AAO:0000967] +xref: UBERON:0001042 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2009-07-16T02:04:46Z + +[Term] +id: XAO:0003228 +name: hypaxial muscle +def: "Type of trunk muscle that lies ventral to the horizontal septum of the vertebrae and is innervated by the ventral ramus of the spinal nerves. The arise from migratory somitic cells along the lower margin of the trunk somites." [UBERON:0008777, XAO:curator] +synonym: "body wall muscle" RELATED [] +xref: UBERON:0008777 +is_a: XAO:0000174 ! skeletal muscle +relationship: develops_from XAO:0001016 ! abdominal myoblast +relationship: develops_from XAO:0005226 ! migrating myoblast +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003230 ! trunk musculature +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2009-07-16T02:14:05Z + +[Term] +id: XAO:0003229 +name: epaxial muscle +def: "Trunk muscle that lies dorsal to the horizontal septum of the vertebrae." [XAO:curators] +synonym: "epaxial muscles" EXACT PLURAL [] +xref: UBERON:0008778 +is_a: XAO:0000174 ! skeletal muscle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003230 ! trunk musculature +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2009-07-16T02:17:32Z + +[Term] +id: XAO:0003230 +name: trunk musculature +def: "Muscle that is located posterior to the head and anterior to the tail and consists of epaxial and hypaxial muscle." [XAO:EJS] +xref: UBERON:0001774 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2009-07-16T02:18:03Z + +[Term] +id: XAO:0003231 +name: absorptive cell +def: "A cell that takes up stuff and metabolizes it." [CL:0000212] +xref: CL:0000212 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:12:02Z + +[Term] +id: XAO:0003232 +name: acid secreting cell +def: "Any of the cell types of the digestive system that secrete amino acid peptides or polypeptides." [CL:0000161] +xref: CL:0000161 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:15:23Z + +[Term] +id: XAO:0003233 +name: acinar cell +def: "Exocrine functioning cells of the pancreas." [CL:0000622] +xref: CL:0000622 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000136 ! pancreas +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2009-07-20T01:16:38Z + +[Term] +id: XAO:0003234 +name: alkali secreting cell +def: "A cell that secretes alkaline substances." [XAO:curators] +xref: CL:0000435 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:17:42Z + +[Term] +id: XAO:0003235 +name: barrier cell +def: "A cell whose primary function is to prevent the transport of stuff across compartments." [CL:0000215] +xref: CL:0000215 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000017 ! NF stage 7 +created_by: eriksegerdell +creation_date: 2009-07-20T01:18:52Z + +[Term] +id: XAO:0003236 +name: barrier epithelial cell +def: "A surface epithelial cell of stratified squamous epithelium of cornea, tongue, oral cavity, esophagus or cloaca." [XAO:curators] +xref: CL:0000073 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2009-07-20T01:19:57Z + +[Term] +id: XAO:0003237 +name: cementoblast +def: "A cell of ectomesenchymal origin concerned with the formation of the layer of cementum on the roots of teeth." [ISBN:0781733901] +xref: CL:0000061 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: eriksegerdell +creation_date: 2009-07-20T01:23:10Z + +[Term] +id: XAO:0003238 +name: chondroblast +def: "A cell that originates from a mesenchymal stem cell and forms chondrocytes (cartilage cells). Chondroblasts that become embedded in the matrix are called chondrocytes." [XAO:curators] +xref: CL:0000058 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004320 ! mesenchymal stem cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2009-07-20T01:24:55Z + +[Term] +id: XAO:0003239 +name: circulating cell +def: "A cell that moves among different tissues of the body, via blood, lymph, or other medium." [CL:0000080] +xref: CL:0000080 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0001010 ! circulatory system +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2009-07-20T01:26:48Z + +[Term] +id: XAO:0003240 +name: digestive enzyme secreting cell +def: "A type of cell, found in the digestive tract, that secrete enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body." [http://en.wikipedia.org/wiki/Digestive_enzyme] +synonym: "digestive enzyme secreting cells" EXACT PLURAL [] +xref: CL:0000470 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2009-07-20T01:30:09Z + +[Term] +id: XAO:0003241 +name: early embryonic cell +def: "A cell found in the embryo before the formation of all the germ layers is complete." [CL:0000007] +xref: CL:0000007 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2009-07-20T01:31:42Z + +[Term] +id: XAO:0003242 +name: morula cell +def: "A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass." [CL:0000360] +xref: CL:0000360 +is_a: XAO:0003241 ! early embryonic cell +relationship: end_stage XAO:1000019 ! NF stage 9 +relationship: start_stage XAO:1000017 ! NF stage 7 +created_by: eriksegerdell +creation_date: 2009-07-20T01:32:43Z + +[Term] +id: XAO:0003244 +name: gastrula cell +def: "A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers." [CL:0000361] +xref: CL:0000361 +is_a: XAO:0003241 ! early embryonic cell +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:32:48Z + +[Term] +id: XAO:0003245 +name: ectodermal cell +def: "A cell of the outer of the three germ layers of the embryo." [CL:0000221] +synonym: "ectoderm cell" EXACT [] +xref: CL:0000221 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:35:11Z + +[Term] +id: XAO:0003246 +name: electrically active cell +def: "A cell whose function is determined by the generation or the reception of an electric signal." [CL:0000211] +xref: CL:0000211 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:37:18Z + +[Term] +id: XAO:0003247 +name: endocrine cell +def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [CL:0000163] +xref: CL:0000163 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004208 ! adenohypophyseal placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000158 ! endocrine system +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell +creation_date: 2009-07-20T01:38:59Z + +[Term] +id: XAO:0003248 +name: endodermal cell +def: "A cell of the inner of the three germ layers of the embryo." [CL:0000223] +synonym: "endoderm cell" EXACT [] +xref: CL:0000223 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:40:37Z + +[Term] +id: XAO:0003249 +name: epithelial cell +def: "A cell that is usually found in a two-dimensional sheet with a free surface." [CL:0000066] +xref: CL:0000066 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003045 ! epithelium +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T01:42:50Z + +[Term] +id: XAO:0003250 +name: exocrine cell +def: "A cell of an exocrine gland, i.e. a gland that discharges its secretion via a duct." [CL:0000152] +xref: CL:0000152 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2009-07-20T01:44:46Z + +[Term] +id: XAO:0003251 +name: hatching gland cell +def: "Individual secretory cells of the hatching gland that secrete an enzyme that dissolves or weakens the egg jelly and facilitates hatching." [XAO:curators] +xref: CL:0000249 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: part_of XAO:0000034 ! hatching gland +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2009-07-20T01:48:20Z + +[Term] +id: XAO:0003252 +name: keratin accumulating cell +def: "A cell that is specialized to accumulate keratins, a family of fibrous structural proteins." [http://en.wikipedia.org/wiki/Keratin] +xref: CL:0000311 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2009-07-20T01:52:10Z + +[Term] +id: XAO:0003253 +name: ligament cell +def: "Type of cell that is capable of generating and maintaining the fibrous connective tissue of the ligament." [XAO:EJS] +xref: CL:0000384 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004031 ! ligament +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: eriksegerdell +creation_date: 2009-07-20T01:52:51Z + +[Term] +id: XAO:0003254 +name: Merkel cell +def: "A modified epidermal cell located in the stratum basale. They are found mostly in areas where sensory perception is acute." [CL:0000242] +xref: CL:0000242 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2009-07-20T01:56:02Z + +[Term] +id: XAO:0003255 +name: mesodermal cell +def: "A cell of the middle germ layer of the embryo." [CL:0000222] +synonym: "mesoderm cell" EXACT [] +xref: CL:0000222 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000050 ! mesoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T02:00:17Z + +[Term] +id: XAO:0003256 +name: mucus secreting cell +def: "A type of epithelial cell, found in the epidermis and digestive system, whose function is to secrete mucin, which dissolves in water to form protective mucus." [http://en.wikipedia.org/wiki/Mucus] +xref: CL:0000319 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2009-07-20T02:06:11Z + +[Term] +id: XAO:0003257 +name: myelin accumulating cell +def: "A cell that is specialized to accumulate myelin." [XAO:EJS] +xref: CL:0000328 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2009-07-20T02:06:51Z + +[Term] +id: XAO:0003258 +name: neuromast mantle cell +def: "A non-sensory cell type surrounding the neuromast support cells and neuromast hair cells, separating the neuromast from the epidermis, and secreting cupula in which the ciliary bundles of all the hair cells are embedded." [CL:0000851] +xref: CL:0000851 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2009-07-20T02:07:36Z + +[Term] +id: XAO:0003259 +name: neuromast support cell +def: "A non-sensory cell of the neuromast that extends between the sensory hair cells from the basement membrane to the apical surface; neuromast support cells are surrounded by neuromast mantle cells." [CL:0000852] +xref: CL:0000852 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2009-07-20T02:09:08Z + +[Term] +id: XAO:0003260 +name: nucleate erythrocyte +def: "An erythrocyte having a nucleus." [CL:0000562] +xref: CL:0000562 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2009-07-20T02:10:45Z + +[Term] +id: XAO:0003261 +name: olfactory epithelial support cell +def: "A non-ciliated columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium." [CL:0000853] +xref: CL:0000853 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2009-07-20T02:14:47Z + +[Term] +id: XAO:0003262 +name: oxygen accumulating cell +def: "A cell that is specialized to accumulate oxygen." [XAO:EJS] +xref: CL:0000329 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T02:16:28Z + +[Term] +id: XAO:0003263 +name: paracrine cell +def: "A secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it." [CL:0000512] +xref: CL:0000512 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T02:17:10Z + +[Term] +id: XAO:0003264 +name: pericyte +def: "A slender, contractile, mesenchymal-like cell found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells." [CL:0000669] +xref: CL:0000669 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2009-07-20T02:21:51Z + +[Term] +id: XAO:0003265 +name: somatic stem cell +def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [CL:0000723] +xref: CL:0000723 +is_a: XAO:0003054 ! stem cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2009-07-20T02:25:31Z + +[Term] +id: XAO:0003266 +name: liver primordium +def: "Embryonic primordium consisting of an endodermal thickening that develops into the liver." [XAO:EJS, ZFA:0000124] +synonym: "liver" BROAD [] +synonym: "liver bud" RELATED [] +xref: UBERON:0003894 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0004270 ! hepato-pancreatic progenitor cell +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2009-07-20T04:05:12Z + +[Term] +id: XAO:0003267 +name: kidney +def: "Either of the pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine. Amphibians (and fish) have a early kidney, the pronephros/pronephric kidney, which consitsts of a single nephron attached to a pronephric duct, which in turn is linked to the cloaca. The pronephros functions as primary filtration system for the embryo while the mesonephric kidney develops. The pronephros starts to degenerate at NF stage 53. The mesonephros starts to form at NF stage 39 and contuinues to grow into the adult kidney." [AAO:0000250, XAO:curators] +xref: UBERON:0002113 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000143 ! urinary system +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2009-08-25T11:34:29Z + +[Term] +id: XAO:0003268 +name: cardiac progenitor cell +def: "Type of presumptive precardiac cell that lie as paired primordia 30 to 45 degrees on either side of the dorsal midline of the embryo. As gastrulation proceeds, these migrate laterally, eventually fusing at the anterior ventral midline, where they differentiate into cardiac tissue. They give rise to the linear heart tube of the fused heart primordium and derive from the cardiac crescent." [PMID:17194606, PMID:2340810] +synonym: "CPC" EXACT [] +is_a: XAO:0005033 ! progenitor cell +relationship: end_stage XAO:1000035 ! NF stage 19 +relationship: part_of XAO:0000336 ! heart primordium +relationship: start_stage XAO:1000024 ! NF stage 14 +created_by: eriksegerdell +creation_date: 2009-12-01T04:42:20Z + +[Term] +id: XAO:0003269 +name: jaw muscle +def: "Type of muscle that arises in the zygomatic arch and closes the jaw." [UBERON:0003681] +xref: UBERON:0011648 +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0005287 ! jaw muscle primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2009-12-01T04:45:17Z + +[Term] +id: XAO:0004000 +name: duct +def: "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination." [UBERON:0000058] +synonym: "ducts" RELATED PLURAL [] +xref: UBERON:0000058 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-06-16T10:41:29Z + +[Term] +id: XAO:0004001 +name: portion of organism substance +def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [CARO:0000004] +xref: UBERON:0000463 +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: lab +creation_date: 2011-06-16T10:56:39Z + +[Term] +id: XAO:0004002 +name: lateral line +def: "Any of the sense organs that detect vibrations carried through water. They develop from a specialized series of dorsolateral ectodermal placodes named lateral line placodes." [XAO:EJS] +xref: UBERON:0010202 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000095 ! lateral line system +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-06-16T11:03:34Z + +[Term] +id: XAO:0004003 +name: anatomical line +def: "Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface." [CARO:0000008] +xref: CARO:0000008 +xref: UBERON:0006800 +is_a: XAO:0000000 ! Xenopus anatomical entity +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: lab +creation_date: 2011-06-16T11:18:59Z + +[Term] +id: XAO:0004004 +name: atypical epithelium +def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [AAO:0010057] +xref: CARO:0000071 +xref: UBERON:0000488 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T10:55:41Z + +[Term] +id: XAO:0004005 +name: extraembryonic structure +def: "Anatomical structure that is contiguous with the embryo and comprises portions of tissue or cells that will not contribute to the embryo." [XAO:EJS, ZFA:0000020] +xref: CARO:0000042 +xref: UBERON:0000478 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: lab +creation_date: 2011-06-20T11:00:46Z + +[Term] +id: XAO:0004006 +name: multilaminar epithelium +def: "Epithelium that consists of more than one layer of epithelial cells." [CARO:0000069] +xref: CARO:0000069 +xref: UBERON:0000486 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T11:10:18Z + +[Term] +id: XAO:0004007 +name: unilaminar epithelium +def: "Epithelium that consists of a single layer of epithelial cells." [CARO:MAH] +xref: CARO:0000073 +xref: UBERON:0000490 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T11:18:11Z + +[Term] +id: XAO:0004008 +name: simple columnar epithelium +def: "Unilaminar epithelium that consists of a single layer of columnar cells." [CARO:MAH] +xref: CARO:0000068 +xref: UBERON:0000485 +is_a: XAO:0004007 ! unilaminar epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T11:19:24Z + +[Term] +id: XAO:0004009 +name: simple cuboidal epithelium +def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [CARO:MAH] +xref: CARO:0000067 +xref: UBERON:0000484 +is_a: XAO:0004007 ! unilaminar epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T11:22:50Z + +[Term] +id: XAO:0004010 +name: simple squamous epithelium +def: "Unilaminar epithelium that consists of a single layer of squamous cells." [CARO:MAH] +xref: CARO:0000070 +xref: UBERON:0000487 +is_a: XAO:0004007 ! unilaminar epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: lab +creation_date: 2011-06-20T11:25:42Z + +[Term] +id: XAO:0004011 +name: axial skeleton +def: "Anatomical cluster of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum." [VSAO:0000056] +xref: UBERON:0005944 +is_a: XAO:0004289 ! skeletal subdivision +relationship: develops_from XAO:0000058 ! somite +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T02:37:32Z + +[Term] +id: XAO:0004012 +name: skeletal element +def: "Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages." [VSAO:0000128] +xref: UBERON:0004765 +is_a: XAO:0003164 ! solid compound organ +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004053 ! skeleton +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-22T03:11:53Z + +[Term] +id: XAO:0004013 +name: cartilage element +def: "Skeletal element that is composed of cartilage tissue and may be permanent or transient." [UBERON:0007844] +synonym: "cartilage" RELATED [] +synonym: "cartilaginous element" EXACT [] +synonym: "chondrogenic element" EXACT [] +xref: UBERON:0007844 +is_a: XAO:0004012 ! skeletal element +relationship: develops_from XAO:0004022 ! cartilaginous condensation +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: xenbase3 +creation_date: 2011-08-22T03:25:09Z + +[Term] +id: XAO:0004014 +name: membrane bone +def: "Bone element that arises as a result of intramembranous ossification." [UBERON:0007842] +xref: UBERON:0007842 +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T03:36:02Z + +[Term] +id: XAO:0004015 +name: dermal bone +def: "Skeletal element that forms superficially in the organism, usually in association with the ectoderm." [UBERON:0008907] +xref: UBERON:0008907 +is_a: XAO:0004014 ! membrane bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004025 ! dermal skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T03:36:25Z + +[Term] +id: XAO:0004016 +name: regenerating skeletal element +def: "Skeletal element that forms as a replacement or substitution of another element or tissue." [UBERON:0010522] +synonym: "replacement element" RELATED [] +xref: UBERON:0010522 +is_a: XAO:0004012 ! skeletal element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004026 ! endoskeleton +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: xenbase3 +creation_date: 2011-08-22T03:37:56Z + +[Term] +id: XAO:0004017 +name: endochondral element +def: "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." [UBERON:0010363] +synonym: "endochondral replacement element" EXACT [] +xref: UBERON:0010363 +is_a: XAO:0004016 ! regenerating skeletal element +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: xenbase3 +creation_date: 2011-08-22T03:38:45Z + +[Term] +id: XAO:0004018 +name: endochondral bone +def: "Replacement bone that forms within cartilage." [UBERON:0002513] +synonym: "ossified chondrogenic bone" EXACT [] +xref: UBERON:0002513 +is_a: XAO:0004017 ! endochondral element +relationship: develops_from XAO:0004022 ! cartilaginous condensation +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T03:39:53Z + +[Term] +id: XAO:0004019 +name: vertebra +def: "Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum." [AAO:0000691] +synonym: "vertebrae" RELATED PLURAL [] +xref: UBERON:0002412 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003074 ! vertebral column +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T03:44:24Z + +[Term] +id: XAO:0004020 +name: process +def: "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, or fin." [VSAO:0000180] +synonym: "bony projection" RELATED [] +synonym: "flange" EXACT [] +synonym: "lamellae" EXACT [] +synonym: "laminae" EXACT [] +synonym: "projection" EXACT [] +synonym: "ridge" EXACT [] +synonym: "shelf" EXACT [] +xref: UBERON:0004529 +is_a: XAO:0003000 ! anatomical structure +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-22T03:58:55Z + +[Term] +id: XAO:0004021 +name: cell condensation +def: "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration." [PMID:8901191, UBERON:0011585] +xref: UBERON:0011585 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T04:26:10Z + +[Term] +id: XAO:0004022 +name: cartilaginous condensation +def: "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." [UBERON:0005863] +synonym: "cartilage condensation" EXACT [] +synonym: "chondrogenic condensation" EXACT [] +xref: UBERON:0005863 +is_a: XAO:0004021 ! cell condensation +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004053 ! skeleton +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T04:27:08Z + +[Term] +id: XAO:0004023 +name: craniofacial skeleton +def: "Cranial skeleton derived from neural crest cells." [VSAO:00000082] +synonym: "cranio-facial skeleton" EXACT [] +is_a: XAO:0004279 ! cranial skeleton +relationship: develops_from XAO:0001001 ! cranial neural crest +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T04:39:54Z + +[Term] +id: XAO:0004024 +name: craniofacial region +def: "Anatomical cluster that encompasses the cranium and facial structures." [XAO:EJS] +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: xenbase3 +creation_date: 2011-08-22T04:42:44Z + +[Term] +id: XAO:0004025 +name: dermal skeleton +def: "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." [UBERON:0010364] +synonym: "dermal skeletal system" RELATED [] +synonym: "dermoskeleton" RELATED [] +synonym: "desmoskeleton" RELATED [] +synonym: "exoskeleton" RELATED [] +xref: UBERON:0010364 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T04:47:40Z + +[Term] +id: XAO:0004026 +name: endoskeleton +def: "Skeletal system that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues." [UBERON:0010362] +synonym: "replacement skeleton" EXACT [] +xref: UBERON:0010362 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T04:49:15Z + +[Term] +id: XAO:0004027 +name: extracellular matrix +def: "Anatomical structure composed of a combination of protein fibers, ground substance and tissue fluid; typically has embedded cells." [VSAO:0000022] +synonym: "ECM" EXACT [] +is_a: XAO:0003162 ! acellular anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-22T04:52:15Z + +[Term] +id: XAO:0004028 +name: fibrocartilage +def: "Cartilage tissue intermediate between hyaline cartilage and dense connective tissue; contains of abundant collagen fibers; chondrocytes often arranged in columns." [UBERON:0001995] +synonym: "fibrocartilage tissue" EXACT [] +xref: UBERON:0001995 +is_a: XAO:0000170 ! cartilage tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T04:54:35Z + +[Term] +id: XAO:0004029 +name: hyaline cartilage tissue +def: "Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance." [UBERON:0001994] +synonym: "hyaline cartilage" EXACT [] +xref: UBERON:0001994 +is_a: XAO:0000170 ! cartilage tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T04:56:37Z + +[Term] +id: XAO:0004030 +name: dense regular connective tissue +def: "Connective tissue that is dominated by collagen fibers organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)." [UBERON:0007846] +synonym: "dense fibrous connective tissue" EXACT [] +synonym: "dense regular collagenous connective tissue" EXACT [] +synonym: "dense regular collagenous tissue" EXACT [] +synonym: "regular dense connective tissue" EXACT [] +xref: UBERON:0007846 +is_a: XAO:0001017 ! connective tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-22T05:06:10Z + +[Term] +id: XAO:0004031 +name: ligament +def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [UBERON:0000211] +xref: UBERON:0000211 +is_a: XAO:0004030 ! dense regular connective tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-22T05:06:59Z + +[Term] +id: XAO:0004032 +name: proteinaceous extracellular matrix +def: "A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity." [VSAO:0000021] +is_a: XAO:0004027 ! extracellular matrix +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-22T05:12:13Z + +[Term] +id: XAO:0004033 +name: avascular GAG-rich matrix +def: "Proteinaceous extracellular matrix that is avascular and consists primarily of glycosaminoglycans." [VSAO:0000059] +synonym: "avascular glycosaminoglycan-rich matrix" EXACT [] +synonym: "cartilage matrix" EXACT [] +synonym: "cartilage-like matrix" EXACT [] +is_a: XAO:0004032 ! proteinaceous extracellular matrix +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-22T05:14:07Z + +[Term] +id: XAO:0004034 +name: mineralized extracellular matrix +def: "Extracellular matrix that is mineralized." [VSAO:0000020] +is_a: XAO:0004032 ! proteinaceous extracellular matrix +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-22T05:16:11Z + +[Term] +id: XAO:0004035 +name: osteoid +def: "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue." [UBERON:0008883] +synonym: "osteoid tissue" EXACT [] +synonym: "pre-bone" EXACT [] +synonym: "prebone" EXACT [] +synonym: "prebone tissue" EXACT [] +xref: UBERON:0008883 +is_a: XAO:0000169 ! bone tissue +is_a: XAO:0005000 ! matrix-based tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T05:17:00Z + +[Term] +id: XAO:0004036 +name: mineralized avascular GAG-rich matrix +def: "Avascular GAG-rich matrix that is mineralized." [VSAO:0000120] +is_a: XAO:0004033 ! avascular GAG-rich matrix +is_a: XAO:0004034 ! mineralized extracellular matrix +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004055 ! mineralized cartilage tissue +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-22T05:18:20Z + +[Term] +id: XAO:0004037 +name: non-mineralized avascular GAG-rich matrix +def: "Avascular GAG-rich matrix that is not mineralized." [VSAO:0000119] +synonym: "non-mineralized cartilage" EXACT [] +is_a: XAO:0004033 ! avascular GAG-rich matrix +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004043 ! non-mineralized cartilage tissue +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-22T05:18:57Z + +[Term] +id: XAO:0004038 +name: skeletal tissue +def: "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support." [UBERON:0004755] +xref: UBERON:0004755 +is_a: XAO:0001017 ! connective tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004012 ! skeletal element +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-22T05:21:47Z + +[Term] +id: XAO:0004039 +name: mineralized tissue +def: "Skeletal tissue that is mineralized." [XAO:EJS] +is_a: XAO:0004038 ! skeletal tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T05:22:34Z + +[Term] +id: XAO:0004040 +name: mineralized bone tissue +def: "Bone tissue mineralized with hydroxyapatite." [UBERON:4000115] +xref: UBERON:4000115 +is_a: XAO:0000169 ! bone tissue +is_a: XAO:0004039 ! mineralized tissue +relationship: develops_from XAO:0004035 ! osteoid +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T05:23:02Z + +[Term] +id: XAO:0004041 +name: mineralized hyaline cartilage tissue +def: "Hyaline cartilage tissue that is mineralized." [VSAO:0000109] +is_a: XAO:0004039 ! mineralized tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-22T05:25:19Z + +[Term] +id: XAO:0004042 +name: muscular system +def: "Anatomical system comprising the sum of all muscles in the body." [UBERON:0000383] +xref: UBERON:0000383 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000168 ! musculoskeletal system +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: xenbase3 +creation_date: 2011-08-22T05:28:16Z + +[Term] +id: XAO:0004043 +name: non-mineralized cartilage tissue +def: "Cartilage tissue that is not mineralized." [VSAO:0000089] +is_a: XAO:0000170 ! cartilage tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T05:30:58Z + +[Term] +id: XAO:0004044 +name: non-mineralized hyaline cartilage tissue +def: "Hyaline cartilage tissue that is not mineralized." [VSAO:0000108] +is_a: XAO:0004029 ! hyaline cartilage tissue +is_a: XAO:0004043 ! non-mineralized cartilage tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-22T05:32:35Z + +[Term] +id: XAO:0004045 +name: odontogenic papilla +def: "Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium." [VSAO:0000025] +synonym: "dental papilla" RELATED [] +synonym: "odontogenic condensation" EXACT [] +xref: UBERON:0001763 +is_a: XAO:0004021 ! cell condensation +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-23T08:43:35Z + +[Term] +id: XAO:0004046 +name: odontoid tissue +def: "Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla." [UBERON:0010365] +synonym: "dental tissue" RELATED [] +synonym: "odontogenic tissue" EXACT [] +xref: UBERON:0010365 +is_a: XAO:0004038 ! skeletal tissue +relationship: develops_from XAO:0004045 ! odontogenic papilla +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004025 ! dermal skeleton +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: xenbase3 +creation_date: 2011-08-23T08:45:58Z + +[Term] +id: XAO:0004047 +name: oropharyngeal papilla +def: "Odontogenic papilla located along the jaws or pharyngeal skeleton." [VSAO:0000030] +synonym: "oropharyngeal dental papilla" EXACT [] +is_a: XAO:0004045 ! odontogenic papilla +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: xenbase3 +creation_date: 2011-08-23T08:47:31Z + +[Term] +id: XAO:0004048 +name: oropharynx +def: "Anatomical cluster that comprises the oral part of the pharynx." [UBERON:0001729] +xref: UBERON:0001729 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003227 ! pharynx +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-23T08:50:17Z + +[Term] +id: XAO:0004049 +name: perichondrium +def: "A layer of dense irregular connective tissue that surrounds the cartilage of developing bone, consisting of two separate layers: an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts, which produce collagenous fibers. The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes. Perichondrium is a type of connective tissue, and also functions in the growth and repair of cartilage. Once vascularized, the perichondrium becomes the periosteum." [http://en.wikipedia.org/wiki/Perichondrium] +xref: UBERON:0002222 +is_a: XAO:0001017 ! connective tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-23T08:52:43Z + +[Term] +id: XAO:0004050 +name: perichordal tissue +def: "Fibrous connective tissue that surrounds the notochord; includes a layer of elastin." [UBERON:0007862] +synonym: "notochord" RELATED [] +synonym: "perichordal connective tissue" EXACT [] +synonym: "perichordal sheath" EXACT [] +synonym: "perichordal sheath tissue" EXACT [] +xref: UBERON:0007862 +is_a: XAO:0001017 ! connective tissue +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-23T08:53:53Z + +[Term] +id: XAO:0004051 +name: dentine +def: "Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular." [UBERON:0001751] +synonym: "dental tissue" RELATED [] +xref: UBERON:0001751 +is_a: XAO:0004046 ! odontoid tissue +relationship: develops_from XAO:0004052 ! pre-dentine +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: xenbase3 +creation_date: 2011-08-23T08:56:47Z + +[Term] +id: XAO:0004052 +name: pre-dentine +def: "Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix." [UBERON:0011587] +synonym: "pre-dentine tissue" EXACT [] +synonym: "predentine tissue" EXACT [] +xref: UBERON:0011587 +is_a: XAO:0004046 ! odontoid tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: xenbase3 +creation_date: 2011-08-23T08:58:05Z + +[Term] +id: XAO:0004053 +name: skeleton +def: "Anatomical cluster that consists of all the skeletal elements (eg, bone, cartilage, and teeth) of the body." [UBERON:0004288] +xref: UBERON:0004288 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003060 ! skeletal system +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-23T09:00:02Z + +[Term] +id: XAO:0004054 +name: vacuolated notochordal tissue +def: "Connective tissue that is matrix-poor with large number of vacuolated cells." [VSAO:0000053] +synonym: "notochord proper" EXACT [] +is_a: XAO:0001017 ! connective tissue +relationship: end_stage XAO:1000074 ! NF stage 62 +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: xenbase3 +creation_date: 2011-08-23T09:02:51Z + +[Term] +id: XAO:0004055 +name: mineralized cartilage tissue +def: "Cartilage tissue that is mineralized." [VSAO:0000088] +is_a: XAO:0000170 ! cartilage tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-23T09:31:53Z + +[Term] +id: XAO:0004056 +name: distal mesenchyme +def: "Mesenchyme cells that proliferate in the progress zone of developing limb buds." [XAO:EJS] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: xenbase3 +creation_date: 2011-08-24T10:22:39Z + +[Term] +id: XAO:0004057 +name: tail tip +def: "Portion of tissue comprising the posterior end of the tail fin." [XAO:EJS] +xref: UBERON:0010162 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004062 ! tail fin +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: xenbase3 +creation_date: 2011-08-24T10:30:32Z + +[Term] +id: XAO:0004058 +name: ampullary nerve +def: "Nerve that is a branch of cranial nerve VIII and innervates the cristae ampullaris." [XAO:EJS, ZFA:0005144] +synonym: "neural ampulla" EXACT [] +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003095 ! vestibulocochlear nerve +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: xenbase3 +creation_date: 2011-08-24T10:33:59Z + +[Term] +id: XAO:0004059 +name: regenerating tissue +def: "A portion of tissue that is re-growing after damage or amputation." [XAO:EJS, ZFA:0005147] +xref: UBERON:0007567 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-24T10:40:19Z + +[Term] +id: XAO:0004060 +name: blastema +def: "A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise." [XAO:EJS, ZFA:0001270] +xref: UBERON:0005306 +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000061 ! NF stage 49 +created_by: xenbase3 +creation_date: 2011-08-24T10:42:35Z + +[Term] +id: XAO:0004061 +name: dorsal fin margin +def: "Fin margin which is part of the dorsal fin." [XAO:EJS] +is_a: XAO:0005171 ! fin margin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000469 ! dorsal tail fin +relationship: part_of XAO:0004063 ! dorsal fin +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: xenbase3 +creation_date: 2011-08-24T10:45:04Z + +[Term] +id: XAO:0004062 +name: tail fin +def: "The fin at the posterior part of the body of the tadpole." [BTO:0001827] +synonym: "caudal fin" RELATED [] +is_a: XAO:0000002 ! fin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: xenbase3 +creation_date: 2011-08-24T10:47:44Z + +[Term] +id: XAO:0004063 +name: dorsal fin +def: "The unsupported flaps of epidermis-covered, loose connective tissue extending the length of the dorsal tail muscle, originating at or near the tail-body junction, and extending posteriorly to slightly beyond the tip of the notochord and tail musculature." [ISBN:0226557634] +is_a: XAO:0000002 ! fin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000041 ! NF stage 25 +created_by: xenbase3 +creation_date: 2011-08-24T10:57:00Z + +[Term] +id: XAO:0004064 +name: ventral tail fin +def: "The ventral part of the tail fin." [XAO:EJS] +is_a: XAO:0000002 ! fin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004062 ! tail fin +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: xenbase3 +creation_date: 2011-08-24T11:06:36Z + +[Term] +id: XAO:0004065 +name: ventral fin margin +def: "Fin margin which is part of the ventral fin." [XAO:EJS] +is_a: XAO:0005171 ! fin margin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004064 ! ventral tail fin +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: xenbase3 +creation_date: 2011-08-24T11:08:17Z + +[Term] +id: XAO:0004066 +name: vegetal endoderm +def: "Portion of the cleavage-stage embryo below the equator and consisting of prospective endodermal cells." [ISBN:0123646200] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000020 ! NF stage 10 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) +created_by: xenbase3 +creation_date: 2011-08-24T11:12:31Z + +[Term] +id: XAO:0004067 +name: suprablastoporal endoderm +def: "During gastrulation, the ring of endodermal cells that overlie the larger sub-blastoral endoderm cells." [ISBN:0123646200] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-24T11:14:55Z + +[Term] +id: XAO:0004068 +name: sub-blastoporal endoderm +def: "During gastrulation, the vegetal endodermal cells that lie just below the ring of smaller suprablastoral endoderm cells." [ISBN:0123646200] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-24T11:15:44Z + +[Term] +id: XAO:0004069 +name: migratory neural crest cell +def: "Neural crest that lose their connections to other neuroepithelial cells during the delamination process and begin to migrate. This involves either partial or complete epithelial-to-mesenchymal transition. Numerous molecules have been demonstrated to guide a neural crest cell's migration to its target tissue." [XAO:CJZ] +synonym: "migratory neural crest" RELATED [] +synonym: "migratory neural crest cells" RELATED PLURAL [] +synonym: "NCMC" RELATED [] +synonym: "neural crest migrating cells" RELATED PLURAL [] +xref: CL:0000333 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: xenbase3 +creation_date: 2011-08-24T11:22:55Z + +[Term] +id: XAO:0004070 +name: hypothalamus +def: "Multi-tissue structure that is part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system." [AAO:0010484] +xref: UBERON:0001898 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T11:29:04Z + +[Term] +id: XAO:0004071 +name: optic chiasm +def: "Decussation of cranial nerve II axons whereby some cross the midline and some remain ipsilateral." [XAO:EJS, ZFA:0000556] +synonym: "OC" EXACT [] +synonym: "optic chiasma" EXACT [] +xref: UBERON:0000959 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: xenbase3 +creation_date: 2011-08-24T11:35:57Z + +[Term] +id: XAO:0004072 +name: suprachiasmatic nucleus +def: "The ventral region of the alar hypothalamus. It is a diencephalic nucleus that is part of the preoptic area and is ventrolateral to the caudal parvocellular preoptic nucleus." [PMID:24122702, XAO:EJS, ZFA:0000441] +synonym: "SC" RELATED [] +synonym: "SCN" EXACT [] +synonym: "suprachiasmatic region" RELATED [] +xref: UBERON:0002034 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004230 ! anterior hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: xenbase3 +creation_date: 2011-08-24T11:41:40Z + +[Term] +id: XAO:0004074 +name: intersomitic region +def: "Anatomical region between somites." [XAO:EJS] +synonym: "intersomitic junction" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: xenbase3 +creation_date: 2011-08-24T12:21:44Z + +[Term] +id: XAO:0004075 +name: intersomitic vessel +def: "Primary blood vessel sprouts that originate from the aorta and grow dorsally between the somites." [PMID:17119151] +synonym: "intersomitic blood vessel" EXACT [] +is_a: XAO:0001011 ! blood vessel +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0001010 ! circulatory system +relationship: part_of XAO:0004074 ! intersomitic region +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-24T12:25:46Z + +[Term] +id: XAO:0004076 +name: intersomitic tendon +def: "A tendon located in the intersomitic region." [XAO:EJS] +is_a: XAO:0000173 ! tendon +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0004074 ! intersomitic region +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: xenbase3 +creation_date: 2011-08-24T12:28:10Z + +[Term] +id: XAO:0004077 +name: intersomitic epithelium +def: "Epithelium located in the intersomitic region." [XAO:EJS] +synonym: "intersomitic membrane" EXACT [] +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0004074 ! intersomitic region +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: xenbase3 +creation_date: 2011-08-24T12:31:19Z + +[Term] +id: XAO:0004078 +name: intersomitic neuron +def: "Neuron located in the intersomitic region." [XAO:EJS] +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0004074 ! intersomitic region +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: xenbase3 +creation_date: 2011-08-24T12:34:45Z + +[Term] +id: XAO:0004079 +name: rhombomere +def: "Any of the transient sequential subdivisions of the developing hindbrain, all posterior to the midbrain-hindbrain boundary." [XAO:EJS] +synonym: "rhombomeres" RELATED PLURAL [] +xref: UBERON:0001892 +is_a: XAO:0004597 ! neuromere +relationship: develops_from XAO:0005026 ! presumptive rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T01:19:56Z + +[Term] +id: XAO:0004080 +name: rhombomere R2 +def: "The 2nd most anterior segment of the developing hindbrain, which along with r3 is dorsal to brancial arch 1." [XAO:curators] +synonym: "r2" EXACT [] +synonym: "rhombomere 2" EXACT [] +xref: UBERON:0005569 +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T02:00:45Z + +[Term] +id: XAO:0004081 +name: rhombomere R3 +def: "The 3rd segment of the developing hindbrain, between rhombomeres r2 and r4, which along with r2 is dorsal to branchial arch 1." [XAO:curators] +synonym: "r3" EXACT [] +synonym: "rhombomere 3" EXACT [] +xref: UBERON:0005507 +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T02:04:40Z + +[Term] +id: XAO:0004082 +name: rhombomere R4 +def: "The 4th segment of the developing hindbrain, between rhombomeres r3 and r5 and dorsal to branchial arch 2." [XAO:curators] +synonym: "r4" EXACT [] +synonym: "rhombomere 4" EXACT [] +xref: UBERON:0005511 +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T02:06:25Z + +[Term] +id: XAO:0004083 +name: rhombomere R5 +def: "The 5th segment of the developing hindbrain, between rhombomeres r4 and r6, and dorsal to branchial arch 3." [XAO:curators] +synonym: "r5" EXACT [] +synonym: "rhombomere 5" EXACT [] +xref: UBERON:0005515 +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T02:08:06Z + +[Term] +id: XAO:0004084 +name: rhombomere R6 +def: "The 6th segment of the developing hindbrain, directly bordering the midbrain-hindbrain boundary, and dorsal to branchial arch 4." [XAO:curators] +synonym: "r6" EXACT [] +synonym: "rhombomere 6" EXACT [] +xref: UBERON:0005519 +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T02:09:39Z + +[Term] +id: XAO:0004085 +name: ionocyte +def: "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In Xenopus there are two distinct types of ionocytes, described as alpha- and beta- subtypes." [CL:0005006] +synonym: "clear cell" BROAD [] +synonym: "FORE cell" RELATED [] +synonym: "IC" EXACT [] +synonym: "intercalated cell" BROAD [] +synonym: "mitochondria-rich cell" BROAD [] +synonym: "narrow cell" BROAD [] +synonym: "proton-secreting cell" RELATED [] +synonym: "PSC" RELATED [] +xref: CL:0005006 +is_a: XAO:0004225 ! non-ciliated epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: part_of XAO:0004091 ! non-neural ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-24T02:12:18Z + +[Term] +id: XAO:0004086 +name: presumptive midbrain-hindbrain boundary +def: "Part of the neural ectoderm that will become the embryonic midbrain-hindbrain boundary." [UBERON:0007281] +xref: UBERON:0007281 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000215 ! central nervous system +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: xenbase3 +creation_date: 2011-08-24T02:24:16Z + +[Term] +id: XAO:0004087 +name: neural fold +def: "One of the two edges of the neural groove." [UBERON:0005062] +xref: UBERON:0005062 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: xenbase3 +creation_date: 2011-08-24T02:42:38Z + +[Term] +id: XAO:0004088 +name: animal pole +def: "The apical region of the animal hemisphere." [XAO:curator] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: part_of XAO:0000202 ! animal hemisphere +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: xenbase3 +creation_date: 2011-08-24T03:18:10Z + +[Term] +id: XAO:0004089 +name: periocular region +def: "Anatomical region that surrounds the eye but is within the orbit." [http://www.merriam-webster.com/medical/periocular] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000040 ! head region +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T03:20:21Z + +[Term] +id: XAO:0004090 +name: optic field +def: "Portion of tissue that is part of the anterior neural plate and will form the optic vesicle." [XAO:EJS, ZFA:0000570] +synonym: "eye primordium" RELATED [] +synonym: "optic primordium" RELATED [] +xref: UBERON:0003071 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000024 ! NF stage 14 +relationship: part_of XAO:0000045 ! pre-chordal neural plate +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: xenbase3 +creation_date: 2011-08-24T03:24:00Z + +[Term] +id: XAO:0004091 +name: non-neural ectoderm +def: "The portion of the embryonic ectoderm, including the preplacodal ectoderm, that does not give rise to nervous tissue." [XAO:EJS] +synonym: "NNE" EXACT [] +xref: UBERON:0005497 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0004132 ! presumptive ectoderm +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000001 ! ectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: xenbase3 +creation_date: 2011-08-24T03:28:19Z + +[Term] +id: XAO:0004092 +name: preplacodal ectoderm +def: "A thick, U-shaped primordium positioned at the border of the future epidermis and the neural plate/neural crest forming regions, in the neural stage embryo. This field of naive ectoderm is subdivided into 3 domains, each with distinct gene expression profiles: the anterior PPE (bottom of the U), the lateral PPE (the curves of the U), and the posterior PPE (arms of the U and adjacent to the neural crest/neural plate border). The PPE differentiates into the sensory placodes, which in turn form the adenohypophysis/anterior pituitary gland and sensory organs (such as the olfactory epithelium, lens, trigeminal nerves, epibranchial nerves, otic vesicles and lateral lines)." [PMID:30291163] +synonym: "placodal area" RELATED [] +synonym: "PPE" EXACT [] +synonym: "pre-placodal ectoderm" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000270 ! sensorial layer of neurectoderm +relationship: develops_from XAO:0004104 ! neural plate border +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000270 ! sensorial layer of neurectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: xenbase3 +creation_date: 2011-08-24T03:30:53Z + +[Term] +id: XAO:0004093 +name: profundal placode +def: "An embryonic structure positioned halfway between the prospective eye and ear, adjacent to the future midbrain-hindbrain boundary. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24." [PMID:21452441] +synonym: "profundus placode" EXACT [] +is_a: XAO:0004620 ! neurogenic placode +relationship: end_stage XAO:1000045 ! NF stage 29 and 30 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-24T03:36:24Z + +[Term] +id: XAO:0004094 +name: lens epithelium +def: "Epithelium that borders the anterior and equitorial region of the lens. Lens growth occurs via the differentiation of additional fibre cells from lens epithelial cells." [XAO:EJS, ZFA:0001326] +xref: UBERON:0001803 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000008 ! lens +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-24T03:40:12Z + +[Term] +id: XAO:0004095 +name: lens transitional zone +def: "The region of the lens of the eye where cells from the anterior epithelial capsule become transformed into the fibers that compose the lens substance." [http://dictionary.reference.com/browse/transitional+zone] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000008 ! lens +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-24T03:43:21Z + +[Term] +id: XAO:0004096 +name: lens fiber cell mass +def: "Portion of tissue comprising fibers that form the bulk of the lens. They are long, thin, transparent cells." [UBERON:0002444] +synonym: "lens fiber" RELATED [] +synonym: "lens fiber cells" RELATED [] +xref: UBERON:0002444 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000008 ! lens +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: xenbase3 +creation_date: 2011-08-24T03:45:09Z + +[Term] +id: XAO:0004097 +name: horizontal cell +def: "A neuron that laterally connects other neurons in the inner nuclear layer of the retina." [CL:0000745] +synonym: "horizontal neuron" RELATED [] +xref: CL:0000745 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-24T03:58:01Z + +[Term] +id: XAO:0004098 +name: bipolar neuron +def: "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body." [CL:0000103] +synonym: "bipolar cell" RELATED [] +xref: CL:0000103 +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-24T04:01:16Z + +[Term] +id: XAO:0004099 +name: amacrine cell +def: "Interneuron of the retina. They integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. They lack large axons." [CL:0000561] +synonym: "amacrine neuron" EXACT [] +xref: CL:0000561 +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003216 ! retinal neural layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-24T04:06:40Z + +[Term] +id: XAO:0004100 +name: retinal ganglion cell +def: "Type of neuron that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [CL:0000740] +synonym: "RGC" EXACT [] +xref: CL:0000740 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003223 ! retinal ganglion cell layer +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-24T04:08:45Z + +[Term] +id: XAO:0004101 +name: optic tract +def: "Diencephalic white matter (tract) that is composed of retinal ganglion cell axons after which they have passed through the optic chiasm." [UBERON:0001908] +xref: UBERON:0001908 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-25T09:25:47Z + +[Term] +id: XAO:0004102 +name: pre-chordal neural plate border +def: "The portion of the neural plate border that is anterior to the mid-hindbrain junction." [XAO:EJS] +synonym: "anterior neural plate border" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000045 ! pre-chordal neural plate +relationship: part_of XAO:0004104 ! neural plate border +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: xenbase3 +creation_date: 2011-08-25T09:47:05Z + +[Term] +id: XAO:0004103 +name: chordal neural plate border +def: "The portion of the neural plate border that is posterior to the mid-hindbrain junction, and from which neural crest cells arise." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000046 ! chordal neural plate +relationship: part_of XAO:0004104 ! neural plate border +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: xenbase3 +creation_date: 2011-08-25T09:47:56Z + +[Term] +id: XAO:0004104 +name: neural plate border +def: "The boundary between non-neural ectoderm and the neural plate of neurula stage embryos, giving rise to the neural crest and cranial placodes." [ISBN:0878933840] +synonym: "NPB" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000001 ! ectoderm +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: xenbase3 +creation_date: 2011-08-25T09:49:21Z + +[Term] +id: XAO:0004105 +name: pronephric tubule +def: "Any of bilaterally paired tubes that perform the resorptive and excretory functions of the pronephros, and which connect the pronephric glomeruli to the pronephric ducts." [ISBN:0127224416, ZFA:0001558] +xref: UBERON:0005310 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0000285 ! pronephric nephron +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: xenbase3 +creation_date: 2011-08-25T09:56:54Z + +[Term] +id: XAO:0004106 +name: regenerating forelimb +def: "A portion of forelimb tissue that is re-growing after damage or amputation." [XAO:curators] +synonym: "forelimb" BROAD [] +is_a: XAO:0004311 ! regenerating limb +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: xenbase3 +creation_date: 2011-08-25T10:02:27Z + +[Term] +id: XAO:0004107 +name: regenerating hindlimb +def: "A portion of hind limb tissue that is re-growing after damage or amputation." [XAO:curators] +synonym: "hind limb" BROAD [] +synonym: "hindlimb" BROAD [] +synonym: "regenerating hind limb" EXACT [] +is_a: XAO:0004311 ! regenerating limb +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: xenbase3 +creation_date: 2011-08-25T10:02:56Z + +[Term] +id: XAO:0004108 +name: regenerating tail +def: "A portion of tail tissue that is re-growing after damage or amputation." [XAO:curators] +synonym: "tail" BROAD [] +synonym: "tail blastema" RELATED [] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000041 ! NF stage 25 +created_by: xenbase3 +creation_date: 2011-08-25T10:03:11Z + +[Term] +id: XAO:0004109 +name: regenerating eye +def: "A portion of eye tissue that is re-growing after damage or amputation." [XAO:curators] +synonym: "eye" BROAD [] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000034 ! NF stage 18 +created_by: xenbase3 +creation_date: 2011-08-25T10:03:22Z + +[Term] +id: XAO:0004110 +name: eye photoreceptor cell +def: "A cell found in the retina of the eye that is specialized to detect and transduce light." [CL:0000210] +xref: CL:0000287 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003215 ! photoreceptor layer +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: xenbase3 +creation_date: 2011-08-25T10:17:43Z + +[Term] +id: XAO:0004111 +name: retinal cone cell +def: "One of the two photoreceptor cell types in the retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [CL:0000573] +synonym: "cone photoreceptor cell" EXACT [] +synonym: "eye photoreceptor cell (cone)" EXACT [] +xref: CL:0000573 +is_a: XAO:0004110 ! eye photoreceptor cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T10:19:21Z + +[Term] +id: XAO:0004112 +name: retinal rod cell +def: "One of the two photoreceptor cell types of the retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [CL:0000604] +synonym: "eye photoreceptor cell (rod)" EXACT [] +synonym: "rod photoreceptor cell" EXACT [] +xref: CL:0000604 +is_a: XAO:0004110 ! eye photoreceptor cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T10:22:13Z + +[Term] +id: XAO:0004113 +name: vegetal pole +def: "The apical region of the vegetal hemisphere." [XAO:curator] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: part_of XAO:0000280 ! vegetal hemisphere +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: xenbase3 +creation_date: 2011-08-25T10:25:07Z + +[Term] +id: XAO:0004114 +name: stage I oocyte +def: "A developing female gamete that is at the pre-vitellogenic stage." [XAO:curators] +synonym: "pre-vitellogenic oocyte" EXACT [] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000083 ! oocyte stage I +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: xenbase3 +creation_date: 2011-08-25T10:27:57Z + +[Term] +id: XAO:0004115 +name: stage II oocyte +def: "A developing female gamete that is at the early vitellogenic stage." [XAO:curators] +synonym: "early vitellogenic oocyte" EXACT [] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000084 ! oocyte stage II +relationship: start_stage XAO:1000084 ! oocyte stage II +created_by: xenbase3 +creation_date: 2011-08-25T10:28:59Z + +[Term] +id: XAO:0004116 +name: stage III oocyte +def: "A developing female gamete that is at the mid-vitellogenic stage." [XAO:curators] +synonym: "mid-vitellogenic oocyte" EXACT [] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000085 ! oocyte stage III +relationship: start_stage XAO:1000085 ! oocyte stage III +created_by: xenbase3 +creation_date: 2011-08-25T10:30:01Z + +[Term] +id: XAO:0004117 +name: stage IV oocyte +def: "A developing female gamete that is at the stage in which polarization along the animal-vegetal axis is established." [XAO:curators] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000086 ! oocyte stage IV +relationship: start_stage XAO:1000086 ! oocyte stage IV +created_by: xenbase3 +creation_date: 2011-08-25T10:30:48Z + +[Term] +id: XAO:0004118 +name: stage V oocyte +def: "A developing female gamete that is at the late vitellogenic stage." [XAO:EJS] +synonym: "late vitellogenic oocyte" EXACT [] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000087 ! oocyte stage V +relationship: start_stage XAO:1000087 ! oocyte stage V +created_by: xenbase3 +creation_date: 2011-08-25T10:31:45Z + +[Term] +id: XAO:0004119 +name: stage VI oocyte +def: "A female gamete that is at the fully grown stage." [XAO:EJS] +synonym: "post-vitellogenic oocyte" EXACT [] +is_a: XAO:0000256 ! oocyte +relationship: end_stage XAO:1000088 ! oocyte stage VI +relationship: start_stage XAO:1000088 ! oocyte stage VI +created_by: xenbase3 +creation_date: 2011-08-25T10:32:29Z + +[Term] +id: XAO:0004120 +name: cardiac jelly +def: "A sheet of extracellular matrix that separates the outer myocardial cell layer from the inner endocardial tube in the early embryonic heart. As the heart is going through the looping stages, this extracellular matrix/cardiac jelly starts to thicken in two regions, the atrioventricular canal region and the ventricular outflow tract region. These two discrete swellings of cardiac jelly are known as cardiac cushions. The cardiac jelly plays a central role in the septation of the heart and comprises most of the thickness of the heart wall at early stages, but disappears as the heart differentiates." [PMID:19890915] +xref: UBERON:0003906 +is_a: XAO:0004027 ! extracellular matrix +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: xenbase3 +creation_date: 2011-08-25T10:49:57Z + +[Term] +id: XAO:0004121 +name: apical ectodermal ridge +def: "A thickened layer of ectodermal cells at the distal tip of a developing limb bud. Along with the zone of polarizing activity, it is a crucial organizing region during limb development." [http://en.wikipedia.org/wiki/Apical_ectodermal_ridge] +synonym: "AER" EXACT [] +synonym: "apical epidermal ridge" EXACT [] +synonym: "epidermal ridge" EXACT [] +xref: UBERON:0004356 +is_a: XAO:0004122 ! proliferative region +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: xenbase3 +creation_date: 2011-08-25T10:53:20Z + +[Term] +id: XAO:0004122 +name: proliferative region +def: "Anatomical cluster that consists of rapidly dividing cells." [XAO:EJS, ZFA:0000098] +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000018 ! NF stage 8 +created_by: xenbase3 +creation_date: 2011-08-25T10:57:21Z + +[Term] +id: XAO:0004123 +name: atrioventricular canal +def: "The part of the heart connecting the atrium to the cardiac ventricle." [PMID:10644411, ZFA:0001315] +synonym: "AV canal" EXACT [] +xref: UBERON:0002087 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: xenbase3 +creation_date: 2011-08-25T11:16:48Z + +[Term] +id: XAO:0004124 +name: atrioventricular canal endocardium +def: "Endocardium that is part of the atrioventricular canal." [PMID:10644411, ZFA:0001616] +xref: UBERON:0003930 +is_a: XAO:0000066 ! endocardium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004123 ! atrioventricular canal +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: xenbase3 +creation_date: 2011-08-25T11:19:42Z + +[Term] +id: XAO:0004125 +name: atrioventricular valve leaflet +def: "A portion of tissue forming a cusp guarding the opening of the atrioventricular valve." [XAO:EJS] +synonym: "atrioventricular valve leaflets" RELATED PLURAL [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005308 ! atrioventricular valve +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T11:20:57Z + +[Term] +id: XAO:0004126 +name: cardiac valve +def: "Portion of tissue that prevents regurgitation of blood from the ventricles to the atria or from the pulmonary arteries or aorta to the ventricles." [UBERON:0000946] +synonym: "heart valve" RELATED [] +xref: UBERON:0000946 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T11:22:41Z + +[Term] +id: XAO:0004127 +name: m. geniohyoideus +alt_id: XAO:0004347 +def: "Muscle that pulls the hyoid apparatus forward and depresses the lower jaw." [XAO:curators] +synonym: "geniohyoideus" EXACT [] +synonym: "mgh" EXACT [] +xref: UBERON:0011151 +is_a: XAO:0004326 ! hypobranchial head muscle +relationship: develops_from XAO:0004444 ! m. geniohyoideus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T11:33:42Z + +[Term] +id: XAO:0004128 +name: m. rectus abdominis +def: "Muscle of the abdomen that continues anteriorly as the m. rectus cervicis." [ISBN:080184780X, XAO:curators] +synonym: "rectus abdominis" EXACT [] +xref: UBERON:0002382 +is_a: XAO:0000172 ! muscle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: xenbase3 +creation_date: 2011-08-25T11:34:32Z + +[Term] +id: XAO:0004129 +name: m. rectus cervicus +alt_id: XAO:0004348 +def: "Muscle that retracts the hyoid and, therefore, the tongue." [XAO:curators] +synonym: "mrc" EXACT [] +synonym: "rectus cervicis" EXACT [] +is_a: XAO:0004326 ! hypobranchial head muscle +relationship: develops_from XAO:0004445 ! m. rectus cervicis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: xenbase3 +creation_date: 2011-08-25T11:34:53Z + +[Term] +id: XAO:0004130 +name: auditory hair cell +def: "A mechanoreceptor cell located in the inner ear that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system." [CL:0000202] +xref: CL:0000202 +is_a: XAO:0004138 ! sensory epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-25T11:41:17Z + +[Term] +id: XAO:0004131 +name: lateral crista +def: "Horizontal (lateral) patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105] +synonym: "horizontal crista" EXACT [] +is_a: XAO:0004138 ! sensory epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-25T11:44:54Z + +[Term] +id: XAO:0004132 +name: presumptive ectoderm +def: "Presumptive structure at the animal pole of the blastula that will develop into ectoderm." [UBERON:0006601] +xref: UBERON:0006601 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000019 ! NF stage 9 +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: xenbase3 +creation_date: 2011-08-26T08:59:00Z + +[Term] +id: XAO:0004133 +name: posterior crista +def: "Posterior patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105] +xref: UBERON:0007275 +is_a: XAO:0004138 ! sensory epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-26T09:03:42Z + +[Term] +id: XAO:0004134 +name: presumptive paraxial mesoderm +def: "Presumptive structure that will develop into paraxial mesoderm." [XAO:curators] +xref: UBERON:0007285 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000050 ! mesoderm +relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000050 ! mesoderm +relationship: start_stage XAO:1000031 ! NF stage 10.5 +created_by: xenbase3 +creation_date: 2011-08-26T09:08:28Z + +[Term] +id: XAO:0004135 +name: rhombic lip +def: "The interface between the dorsal neuroepithelium and the roof plate of the fourth ventricle. The source of a number of migratory neuron populations of the hindbrain." [UBERON:0006215] +xref: UBERON:0006215 +is_a: XAO:0003043 ! primordium +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-26T09:25:54Z + +[Term] +id: XAO:0004136 +name: saccular macula +def: "Portion of tissue that is a patch of thickened, pseudostratified epithelium in the inner ear, consisting of regular arrays of sensory hair cells interspersed with supporting cells. The macula saccule senses linear acceleration and gravity." [PMID:20201105] +xref: UBERON:0002212 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-26T09:31:03Z + +[Term] +id: XAO:0004137 +name: anterior crista +def: "Anterior patch of cristae/sensory epithelia cells of the inner ear." [PMID:20201105] +synonym: "anterior cristae" RELATED PLURAL [] +xref: UBERON:0007274 +is_a: XAO:0004138 ! sensory epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-26T09:42:59Z + +[Term] +id: XAO:0004138 +name: sensory epithelial cell +def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibuloauditory systems; they contain sensory cells surrounded by supportive, non-receptive cells." [CL:0000098] +xref: CL:0000098 +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 +created_by: xenbase3 +creation_date: 2011-08-26T09:52:26Z + +[Term] +id: XAO:0004139 +name: outflow tract +def: "The portion of the heart through which blood flows into the pulmocutaneous and systemic arteries. It is derived from cardiac precusor cells of the secondary heart field, and septation is incomplete." [PMID:10644411, PMID:20671188, UBERON:0004145] +xref: UBERON:0004145 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004190 ! cardiac neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: xenbase3 +creation_date: 2011-08-26T10:12:24Z + +[Term] +id: XAO:0004140 +name: ventricular outflow tract +def: "A portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle." [PMID:10644411, UBERON:0005337] +xref: UBERON:0005337 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004139 ! outflow tract +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: xenbase3 +creation_date: 2011-08-26T10:17:59Z + +[Term] +id: XAO:0004141 +name: spiral septum +def: "The thin, spiral-shaped membranous structure within the ventricular outflow tract of the heart." [PMID:10644411] +synonym: "spiral septa" RELATED PLURAL [] +xref: UBERON:0002099 +is_a: XAO:0005422 ! septum +relationship: develops_from XAO:0004186 ! secondary heart field +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004140 ! ventricular outflow tract +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: xenbase3 +creation_date: 2011-08-26T10:22:27Z + +[Term] +id: XAO:0004142 +name: vestibulocochlear ganglion +def: "Ganglion that provides afferent innervation for hair cells associated with both the auditory and vestibular components of the inner ear. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII." [PMID:21452441] +synonym: "statoacoustic (VIII) ganglion" EXACT [] +synonym: "statoacoustic ganglion" EXACT [] +synonym: "vestibulocochlear ganglia" RELATED PLURAL [] +synonym: "vestibulocochlear VIII ganglion" EXACT [] +xref: UBERON:0002827 +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0000223 ! otic placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003095 ! vestibulocochlear nerve +relationship: start_stage XAO:1000037 ! NF stage 21 +created_by: xenbase3 +creation_date: 2011-08-26T10:41:25Z + +[Term] +id: XAO:0004143 +name: vascular plexus +def: "Any network of intercommunicating blood vessels." [XAO:curators] +xref: UBERON:0005629 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: xenbase3 +creation_date: 2011-08-26T10:59:34Z + +[Term] +id: XAO:0004144 +name: anterior ventral blood island +def: "Region that is overlapping, anterior, and dorsal to the main body of the ventral blood island." [PMID:21069823] +synonym: "aVBI" EXACT [] +synonym: "blood island" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0004473 ! ventral mesoderm +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: part_of XAO:0000067 ! ventral blood island +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: xenbase3 +creation_date: 2011-08-26T11:20:29Z + +[Term] +id: XAO:0004145 +name: vestibular apparatus +def: "A small, oval, bony chamber of the labyrinth. The vestibule contains the utricle and saccule, organs which are part of the balancing apparatus of the ear." [UBERON:0005236] +xref: UBERON:0001862 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: xenbase3 +creation_date: 2011-08-26T11:46:49Z + +[Term] +id: XAO:0004146 +name: hemangioblast +def: "A pluripotent cell in the ventral blood island that can give rise to mesenchymal cells including erythrocytes and endothelial cells." [PMID:11495698] +xref: CL:0002418 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: lab +creation_date: 2011-08-30T10:27:52Z + +[Term] +id: XAO:0004147 +name: vitelline vein +def: "One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids." [UBERON:0005487] +synonym: "vascular vitelline network" EXACT [] +synonym: "vitelline veins" RELATED PLURAL [] +xref: UBERON:0005487 +is_a: XAO:0000115 ! vein +relationship: develops_from XAO:0004144 ! anterior ventral blood island +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-30T10:36:35Z + +[Term] +id: XAO:0004148 +name: myeloid cell +def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763] +xref: CL:0000763 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004144 ! anterior ventral blood island +relationship: develops_from XAO:0004628 ! posterior ventral blood island +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: lab +creation_date: 2011-08-30T10:44:28Z + +[Term] +id: XAO:0004149 +name: endothelial cell +def: "Cell that comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115] +xref: CL:0000115 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000356 ! vascular endothelium +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: lab +creation_date: 2011-08-30T10:48:16Z + +[Term] +id: XAO:0004150 +name: erythroid cell +def: "An immature or mature cell in the lineage leading to and including erythrocytes." [CL:0000764] +synonym: "erythroid lineage cell" RELATED [] +xref: CL:0000764 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004144 ! anterior ventral blood island +relationship: develops_from XAO:0004628 ! posterior ventral blood island +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000122 ! hematological system +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: lab +creation_date: 2011-08-30T10:53:48Z + +[Term] +id: XAO:0004151 +name: tail vasculature +def: "Posterior vascular precursor cells of the tail region." [PMID:21069823] +xref: UBERON:0010204 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-30T11:01:48Z + +[Term] +id: XAO:0004152 +name: head vasculature +def: "The blood vessels of the head region." [PMID:21069823] +xref: UBERON:0002200 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: lab +creation_date: 2011-08-30T11:05:38Z + +[Term] +id: XAO:0004153 +name: retinal blood vessel +def: "Blood vessels of the retina. May be visible in periocular stainings." [XAO:curators] +synonym: "retinal blood vessels" RELATED PLURAL [] +xref: UBERON:0004864 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: lab +creation_date: 2011-08-30T11:39:54Z + +[Term] +id: XAO:0004154 +name: hyaloid blood vessel +def: "Vessels that are associated with the posterior region of the lens." [XAO:EJS, ZFA:0005046] +synonym: "hyaloid blood vessels" EXACT PLURAL [] +synonym: "hyaloid vessel" EXACT [] +synonym: "hyaloid vessels" EXACT PLURAL [] +xref: UBERON:0005492 +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-08-30T11:43:24Z + +[Term] +id: XAO:0004155 +name: hyaloid artery +def: "The hyaloid artery is a branch of the ophthalmic artery, which is itself a branch of the internal carotid artery. It is contained within the optic stalk of the eye and extends from the optic disc through the vitreous humor to the lens. Its purpose is to supply nutrient to the developing lens." [UBERON:0002270] +xref: UBERON:0002270 +is_a: XAO:0004154 ! hyaloid blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-08-30T11:47:17Z + +[Term] +id: XAO:0004156 +name: hyaloid vein +def: "Vein internal to the eye." [UBERON:006011] +xref: UBERON:0006011 +is_a: XAO:0004154 ! hyaloid blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-08-30T11:51:28Z + +[Term] +id: XAO:0004157 +name: hyaloid vascular plexus +def: "Network of intersecting blood vessels associated with the posterior region of the lens." [XAO:EJS] +xref: UBERON:0005607 +is_a: XAO:0004154 ! hyaloid blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-08-30T11:53:20Z + +[Term] +id: XAO:0004158 +name: anterior cerebral vein +def: "Vein that crosses the head dorsally at NF stage 37/38 and drains into the vena capitis medialis." [PMID:12606281] +xref: UBERON:0001672 +is_a: XAO:0004160 ! cerebral vein +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-30T12:00:30Z + +[Term] +id: XAO:0004159 +name: posterior cerebral vein +def: "Vein that drains the dorsal longitudinal vessel and the caudal portions of the venous capillary network of the medulla oblongata. The cerebral veins cross the head dorsally at NF stage 37-38. It drains into the vena capitis lateralis." [PMID:12606281, ZFA:0005027] +is_a: XAO:0004160 ! cerebral vein +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-30T12:13:01Z + +[Term] +id: XAO:0004160 +name: cerebral vein +def: "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The veins are the anterior cerebral veins, posterior cerebral veins, and middle cerebral vein which cross dorsally between the bilateral vena capitis lateralis." [UBERON:001663] +xref: UBERON:0001663 +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-30T12:16:59Z + +[Term] +id: XAO:0004161 +name: middle cerebral vein +def: "Type of vein that crosses the head dorsally at NF stage 37/38 and drains into the vena capitis lateralis." [PMID:12606281] +synonym: "mid cerebral vein" EXACT [] +synonym: "mid-cerebral vein" EXACT [] +is_a: XAO:0004160 ! cerebral vein +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-30T12:23:07Z + +[Term] +id: XAO:0004162 +name: pulmonary artery +def: "Type of artery that carries blood from the heart to the lungs. They are the only arteries that carry deoxygenated blood. Develops from aortic arch 6." [UBERON:0002012] +xref: UBERON:0002012 +is_a: XAO:0000114 ! artery +relationship: develops_from XAO:0000353 ! aortic arch 6 +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: lab +creation_date: 2011-08-30T01:59:48Z + +[Term] +id: XAO:0004163 +name: angioblast +def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [CL:0000566] +synonym: "angioblasts" EXACT PLURAL [] +xref: CL:0000566 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: lab +creation_date: 2011-08-30T02:11:31Z + +[Term] +id: XAO:0004164 +name: intersomitic vein +def: "Type of vein that sprouts from the posterior cardinal vein, growing dorsally between the somites, and then joining, and draining the dorsal longitudinal anastomosing vessel." [PMID:12606281] +is_a: XAO:0004075 ! intersomitic vessel +relationship: develops_from XAO:0000241 ! posterior cardinal vein +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-30T02:26:59Z + +[Term] +id: XAO:0004165 +name: intersomitic artery +def: "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." [PMID:12606281] +xref: UBERON:0006001 +is_a: XAO:0004075 ! intersomitic vessel +relationship: develops_from XAO:0000051 ! dorsal aorta +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-30T02:29:23Z + +[Term] +id: XAO:0004166 +name: left omphalomesenteric vein +def: "In the trunk region, one of the veins into which the subintestinal vein drains, and which breaks up to merge with the vitelline network at NF stage 40." [PMID:12606281] +is_a: XAO:0000376 ! omphalomesenteric vein +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-08-31T10:32:04Z + +[Term] +id: XAO:0004167 +name: metencephalic artery +def: "The artery that crosses the brain dorsally, and meets the metencephalic vein." [PMID:12606281] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-31T10:38:54Z + +[Term] +id: XAO:0004168 +name: metencephalic vein +def: "The vein that crosses the brain dorsally, parallel with the mid-cerebral vein, and meets the metencephalic artery." [PMID:12606281] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-31T10:43:06Z + +[Term] +id: XAO:0004169 +name: ophthalmic vein +def: "The dorsal branch/remnant of the vena capitis medialis, that drains blood from the eye. Together with the opthalmic artery, form a double ring encircling the eye and retina." [PMID:12606281] +xref: UBERON:0011191 +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: part_of XAO:0004170 ! vena capitis medialis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: lab +creation_date: 2011-08-31T11:03:57Z + +[Term] +id: XAO:0004170 +name: vena capitis medialis +def: "One of the major dorsal head veins that drains into the anterior cardinal vein, the other being the vena capitis lateralis." [PMID:12606281] +synonym: "VCM" EXACT [] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-08-31T11:14:19Z + +[Term] +id: XAO:0004171 +name: vena capitis lateralis +def: "One of the major dorsal head veins that drains into the anterior cardinal vein, the other being the vena capitis medialis." [PMID:12606281] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-31T11:22:11Z + +[Term] +id: XAO:0004172 +name: subintestinal vein +def: "Vein that is formed from and drains into the left omphalomesentric vein, and by NF stage 40, it is on the left side of the gut. It moves to the most ventral aspect of the gut during stage 41, and is on the right side of the gut by stage 43." [PMID:12606281] +xref: UBERON:0011944 +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004151 ! tail vasculature +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: lab +creation_date: 2011-08-31T11:24:56Z + +[Term] +id: XAO:0004173 +name: mesencephalic artery +def: "The major artery of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic vein." [PMID:12606281] +xref: UBERON:0001634 +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-08-31T12:02:13Z + +[Term] +id: XAO:0004174 +name: mesencephalic vein +def: "The major vein of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic artery." [PMID:12606281] +xref: UBERON:0010205 +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-08-31T12:04:02Z + +[Term] +id: XAO:0004175 +name: nasociliary artery +def: "The main artery of the olfactory region which arises from the cerebral artery at NF stage 41." [PMID:12606281] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: lab +creation_date: 2011-08-31T12:13:11Z + +[Term] +id: XAO:0004176 +name: optic choroid vascular plexus +def: "A plexus of capillaries that is located anteromedial to the eye. It is a capillary layer in the choroid. It is in contact with the basal surface of the retinal pigmented epithelium and supplies the photoreceptors with oxygen and nutrients. The fused basement membrane of this capillary layer and the pigmented epithelium is called Bruch's membrane." [ISBN:1402073755] +synonym: "capillary lamina of choroid" EXACT [] +synonym: "choriocapillaris" EXACT [] +synonym: "choroidal vascular plexus" EXACT [] +xref: UBERON:0010078 +is_a: XAO:0004143 ! vascular plexus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000056 ! NF stage 44 +created_by: lab +creation_date: 2011-08-31T12:26:08Z + +[Term] +id: XAO:0004177 +name: dorsal longitudinal anastomosing vessel +def: "Vessel into which intersomitic vessels enter in a regular pattern at each intersomitic junction. Posterior to the gut, the DLAV drains into the fused posterior cardinal vein by a minor right branch and a major left branch. By NF stage 36 the DLAV extends fully to the tip of the tail." [PMID:12606281] +synonym: "DLAV" EXACT [] +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-31T01:27:30Z + +[Term] +id: XAO:0004178 +name: dorsal longitudinal anastomosing vessel - left branch +def: "The major (left) branch of the dorsal longitudinal anastomosing vessel (dlav); it remains as the sole branch after the right branch breaks up at NF stage 44." [PMID:12606281] +synonym: "DLAV - left branch" RELATED [] +is_a: XAO:0004177 ! dorsal longitudinal anastomosing vessel +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-31T01:33:06Z + +[Term] +id: XAO:0004179 +name: dorsal longitudinal anastomosing vessel - right branch +def: "The minor (right) branch of the dorsal longitudinal anastomosing vessel (dlav); the right branch disappears during NF stage 44." [PMID:12606281] +synonym: "DLAV - right branch" EXACT [] +is_a: XAO:0004177 ! dorsal longitudinal anastomosing vessel +relationship: end_stage XAO:1000057 ! NF stage 45 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-08-31T01:38:24Z + +[Term] +id: XAO:0004180 +name: olfactory bulb +def: "Part of the telencephalon, comprising paired anterior outgrowths of either of the cerebral hemispheres in which the olfactory nerve exits. The olfactory bulbs begin to fuse at NF stage 50, and fusion is complete around NF stage 58. The cerebral vein loops around the olfactory bulb by NF stage 43." [AAO:0010165, ISBN:0815318960] +synonym: "bulbus olfactorius" EXACT [] +synonym: "OB" EXACT [] +synonym: "olfactory lobe" RELATED [] +xref: UBERON:0002264 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: lab +creation_date: 2011-08-31T02:08:00Z + +[Term] +id: XAO:0004181 +name: cardiac myocyte +def: "Type of myocyte that is responsible for heart contraction." [CL:0000746] +synonym: "cardiac muscle cell" RELATED [] +synonym: "cardiac muscle cells" RELATED PLURAL [] +synonym: "cardiac myocytes" RELATED PLURAL [] +synonym: "cardiomyocyte" RELATED [] +synonym: "cardiomyocytes" RELATED PLURAL [] +xref: CL:0000746 +is_a: XAO:0004475 ! myocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000065 ! myocardium +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-09-02T09:18:06Z + +[Term] +id: XAO:0004182 +name: pericardium +def: "The outer membrane/wall of the developing heart, surrounding the myocardium. Peritoneum that surrounds the heart." [AAO:0010817] +xref: UBERON:0002407 +is_a: XAO:0000139 ! peritoneum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: lab +creation_date: 2011-09-02T09:40:58Z + +[Term] +id: XAO:0004183 +name: pericardial muscle +def: "Muscle that is paired and runs anterio-posteriorly along the heart and is covered with epicardium." [XAO:EJS, ZFA:0001653] +is_a: XAO:0000172 ! muscle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: lab +creation_date: 2011-09-02T09:46:21Z + +[Term] +id: XAO:0004184 +name: pericardial roof +def: "The dorsal region of the pericardium." [PMID:18598690] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004182 ! pericardium +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: lab +creation_date: 2011-09-02T10:01:41Z + +[Term] +id: XAO:0004185 +name: primary heart field +def: "The field of cardiac progenitor cells that form the heart tube in the embryonic heart." [PMID:18598690, PMID:20671188] +synonym: "FHF" RELATED [] +synonym: "first heart field" EXACT [] +synonym: "PHF" RELATED [] +xref: UBERON:0004140 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000235 ! cardiac mesoderm +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000035 ! NF stage 19 +created_by: lab +creation_date: 2011-09-02T10:49:26Z + +[Term] +id: XAO:0004186 +name: secondary heart field +def: "The population of cells located in the splanchnic mesoderm that contribute to the formation of the spiral septum of the outflow tract of the embryonic heart; it is located anterior to the primary heart field." [PMID:18598690, PMID:20671188] +synonym: "second heart field" EXACT [] +synonym: "SHF" RELATED [] +xref: UBERON:0009889 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000235 ! cardiac mesoderm +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000035 ! NF stage 19 +created_by: lab +creation_date: 2011-09-02T10:56:21Z + +[Term] +id: XAO:0004187 +name: anterior branchial crest +def: "Branchial crest that is the 3rd neural crest stream and lays between hyoid crest and posterior branchial crest." [PMID:21490068] +synonym: "ABC" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000026 ! branchial crest +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000026 ! branchial crest +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: lab +creation_date: 2011-09-02T11:14:48Z + +[Term] +id: XAO:0004188 +name: posterior branchial crest +def: "Branchial crest that is the most posterior of the five neural crest streams." [PMID:21490068] +synonym: "PBC" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000026 ! branchial crest +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000026 ! branchial crest +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: lab +creation_date: 2011-09-02T11:18:11Z + +[Term] +id: XAO:0004189 +name: endocardial cushion +def: "The discrete swellings of cardiac jelly in the outflow tract and ventricular walls of the developing embryonic heart." [PMID:21490068] +synonym: "cardiac cushion" RELATED [] +xref: UBERON:0002062 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000048 ! NF stage 33 and 34 +relationship: part_of XAO:0000064 ! heart +relationship: part_of XAO:0000066 ! endocardium +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-09-02T02:17:35Z + +[Term] +id: XAO:0004190 +name: cardiac neural crest +def: "Neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to contribute to the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart where it contributes to connective tissue (septa) that separates the vessels of the heart. Cardiac neural crest develops into melanocytes, cartilage, connective tissue and neurons of some pharyngeal arches." [http://en.wikipedia.org/wiki/Cardiac_neural_crest_complex] +xref: UBERON:0000095 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: lab +creation_date: 2011-09-02T02:35:20Z + +[Term] +id: XAO:0004191 +name: vagal neural crest +def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the sacral neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. These cells, between the head and trunk, contribute post-cranially to the heart and gut, the chromatophores (pigment cells) of the epidermis, and the majority of the neurons and glial cells of the enteric nervous system. Both vagal and sacral neural crest cells contribute to the enteric nervous system in the hindgut." [PMID:9753687, XAO:CJZ] +synonym: "VNC" EXACT [] +xref: UBERON:0005428 +is_a: XAO:0005327 ! chordal neural crest +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: lab +creation_date: 2011-09-02T02:50:42Z + +[Term] +id: XAO:0004192 +name: sacral neural crest +def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. Together with the vagal neural crest cells, they develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. Sacral crest cells are associated with extrinsic nerve fibers of the hindgut and colon." [XAO:CJZ] +synonym: "SNC" EXACT [] +xref: UBERON:0010075 +is_a: XAO:0005327 ! chordal neural crest +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: lab +creation_date: 2011-09-02T02:53:34Z + +[Term] +id: XAO:0004193 +name: ossicle +def: "Skeletal element that is often isolated, small, and variable in composition." [UBERON:0010911] +xref: UBERON:0010911 +is_a: XAO:0004012 ! skeletal element +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-09-13T09:36:09Z + +[Term] +id: XAO:0004194 +name: appendicular ossicle +def: "Ossicle that is part of the appendicular skeleton." [UBERON:0011141] +xref: UBERON:0011141 +is_a: XAO:0004193 ! ossicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003166 ! appendicular skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-09-13T09:38:19Z + +[Term] +id: XAO:0004195 +name: cellular bone tissue +def: "Mineralized bone tissue that always includes non-terminally differentiated osteoblasts and osteocytes." [UBERON:4000118] +xref: UBERON:4000118 +is_a: XAO:0004040 ! mineralized bone tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-09-13T09:43:56Z + +[Term] +id: XAO:0004196 +name: cementum +def: "Odontoid tissue that is deposited by cementoblasts onto dentine tissue and functions to attach teeth, odontodes and other odontogenic derivatives to bone tissue and the integument." [UBERON:0001753] +synonym: "bone of attachment" RELATED [] +xref: UBERON:0001753 +is_a: XAO:0004046 ! odontoid tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T09:46:43Z + +[Term] +id: XAO:0004197 +name: elastic cartilage tissue +def: "Cartilage tissue that is flexible and contains abundant elastic fibers." [UBERON:0001996] +synonym: "elastic cartilage" EXACT [] +xref: UBERON:0001996 +is_a: XAO:0004044 ! non-mineralized hyaline cartilage tissue +relationship: develops_from XAO:0004022 ! cartilaginous condensation +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: lab +creation_date: 2011-09-13T09:48:42Z + +[Term] +id: XAO:0004198 +name: enamel +def: "Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. It develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix." [VSAO:0000065] +synonym: "enamel tissue" EXACT [] +synonym: "tooth enamel" EXACT [] +xref: UBERON:0001752 +is_a: XAO:0004046 ! odontoid tissue +relationship: develops_from XAO:0004202 ! pre-enamel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T09:51:23Z + +[Term] +id: XAO:0004199 +name: enameloid +def: "Skeletal tissue that is hypermineralized and aprismatic and deposited by a combination of ameloblasts and odontoblasts that are excluded from the matrix. It develops from pre-enameloid tissue." [UBERON:0011692] +synonym: "bitypic enamel" EXACT [] +synonym: "durodentine" EXACT [] +synonym: "enameloid tissue" EXACT [] +synonym: "vitrodentine" EXACT [] +xref: UBERON:0011692 +is_a: XAO:0004046 ! odontoid tissue +relationship: develops_from XAO:0004203 ! pre-enameloid +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T09:56:25Z + +[Term] +id: XAO:0004200 +name: non-mineralized chondroid tissue +def: "Chondroid tissue that is not mineralized." [XAO:EJS] +is_a: XAO:0004038 ! skeletal tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: lab +creation_date: 2011-09-13T09:59:02Z + +[Term] +id: XAO:0004201 +name: odontode tissue +def: "Skeletal tissue that is avascular tubular mineralized matrix, primarily made of dentine that is deposited by odontoblasts that are excluded from the matrix; develops from pre-dentine tissue." [VSAO:0000123] +synonym: "dental tissue" RELATED [] +is_a: XAO:0004046 ! odontoid tissue +relationship: develops_from XAO:0004052 ! pre-dentine +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T10:00:35Z + +[Term] +id: XAO:0004202 +name: pre-enamel +def: "Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix." [UBERON:0011588] +synonym: "pre-enamel tissue" EXACT [] +synonym: "preenamel tissue" EXACT [] +xref: UBERON:0011588 +is_a: XAO:0004046 ! odontoid tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T10:08:54Z + +[Term] +id: XAO:0004203 +name: pre-enameloid +def: "Odontoid tissue that is avascular non-mineralized matrix that is deposited by odontoblasts and ameloblasts that are excluded from the matrix." [UBERON:0011688] +synonym: "non-mineralized enameloid tissue" EXACT [] +xref: UBERON:0011688 +is_a: XAO:0004046 ! odontoid tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000072 ! NF stage 60 +created_by: lab +creation_date: 2011-09-13T10:15:16Z + +[Term] +id: XAO:0004204 +name: sesamoid +def: "Replacement element; an ossicle; often an endochondral replacement element that has cartilage and bone states that develops in dense regular connective tissue (e.g., tendons and ligaments)." [VSAO:0000137] +xref: UBERON:0013631 +is_a: XAO:0004193 ! ossicle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000074 ! NF stage 62 +created_by: lab +creation_date: 2011-09-13T10:23:39Z + +[Term] +id: XAO:0004205 +name: gall bladder primordium +def: "A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops." [ISBN:0815318960] +xref: UBERON:0006242 +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0005128 ! posterior foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: lab +creation_date: 2011-09-13T01:15:58Z + +[Term] +id: XAO:0004206 +name: anterior placodal area +def: "One of the 3 domains of the U-shaped preplacodal ectoderm (PPE), which lies abutting and anterior to the neural plate." [ISBN:0878933840] +synonym: "anterior preplacodal ectoderm" RELATED [] +synonym: "APA" EXACT [] +synonym: "APPE" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0004092 ! preplacodal ectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: lab +creation_date: 2011-09-13T01:29:48Z + +[Term] +id: XAO:0004207 +name: posterior placodal area +def: "One of the 3 domains of the U-shaped preplacodal ectoderm (PPE), which lies abutting and lateral to the chordal neural plate border and neural crest." [ISBN:0878933840] +synonym: "posterior preplacodal ectoderm" RELATED [] +synonym: "PPA" EXACT [] +synonym: "PPPE" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0004092 ! preplacodal ectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: lab +creation_date: 2011-09-13T01:40:58Z + +[Term] +id: XAO:0004208 +name: adenohypophyseal placode +def: "The small pre-placodal ectoderm area that develops at the midline of the anterior neural ridge, abutting the anterior neural plate, and invaginates to form Rathke's pouch, which in turn forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary." [ISBN:0878933840] +synonym: "pituitary placode" EXACT [] +xref: UBERON:0009122 +is_a: XAO:0005283 ! non-neurogenic ectodermal placode +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0004091 ! non-neural ectoderm +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: lab +creation_date: 2011-09-13T01:47:17Z + +[Term] +id: XAO:0004209 +name: anterior neural ridge +def: "The region that delineates the rostral boundary of the neural plate in the neural stage embryo, and is devoid of neural crest cells. It gives rise to the pre-placodal region, some elements of the forebrain, and the anterior lobe of the pituitary gland." [ISBN:0878933840] +synonym: "ANR" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: lab +creation_date: 2011-09-13T02:26:18Z + +[Term] +id: XAO:0004210 +name: infundibulum +def: "The region of the diencephalon above Rathke's pouch, and forms the posterior lobe of the pituitary." [XAO:curators] +synonym: "hypophysial stalk" EXACT [] +synonym: "infundibulum of hypothalamus" EXACT [] +synonym: "pituitary stalk" EXACT [] +xref: UBERON:0002434 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: lab +creation_date: 2011-09-13T02:33:45Z + +[Term] +id: XAO:0004211 +name: facial epibranchial placode +def: "The most anterior of the epibranchial placodes, associated with the 1st pharyngeal cleft and contributing to the distal ganglia of cranial nerve VII (facial nerve)." [ISBN:0878933840] +synonym: "epVII" EXACT [] +synonym: "geniculate placode" EXACT [] +xref: UBERON:0009124 +is_a: XAO:0000284 ! epibranchial placode +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-09-14T09:21:23Z + +[Term] +id: XAO:0004212 +name: glossopharyngeal epibranchial placode +def: "The central of the three epibranchial placodes, associated with the 2nd pharyngeal cleft and contributing to the distal ganglia of cranial nerve IX (glossopharyngeal nerve)." [ISBN:0878933840] +synonym: "epIX" EXACT [] +synonym: "petrosal placode" EXACT [] +xref: UBERON:0009125 +is_a: XAO:0000284 ! epibranchial placode +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-09-14T09:25:28Z + +[Term] +id: XAO:0004213 +name: vagal epibranchial placode +def: "The most posterior of the epibranchial placodes, in 3 distinct zones, associated with the 3rd to 6th pharyngeal clefts, and contributing to the facial, lateral line and glossopharyngeal ganglion." [ISBN:0878933840] +synonym: "nodose placode" EXACT [] +synonym: "nodose placodes" EXACT PLURAL [] +synonym: "vagal epibranchial placodes" EXACT PLURAL [] +xref: UBERON:0009126 +is_a: XAO:0000284 ! epibranchial placode +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: lab +creation_date: 2011-09-14T09:36:07Z + +[Term] +id: XAO:0004214 +name: accessory nerve +def: "Small motor nerve that emerges from the lateral wall of the medulla with the roots of the vagus nerve, and innervates a single pectoral suspensory muscle, the m. cucullaris." [ISBN:080184780X] +synonym: "accessorius" EXACT [] +synonym: "cranial nerve XI" EXACT [] +xref: UBERON:0002019 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-09-14T10:03:25Z + +[Term] +id: XAO:0004215 +name: hypoglossal nerve +def: "Nerve that leads to the muscles of the tongue (mm geniohyoideus, genioglossus, hyoglossus, and rectus cervicis) and has both sensory and motor functions." [ISBN:080184780X] +comment: Duellman and Trueb (pg. 395) note that although the primordia of this nerve are in the 1st and 2nd spinal nerves, this nerve contains fibers representing the hypoglossal nerve in amniotes and is thus considered one of the cranial nerves. +synonym: "cranial nerve XII" EXACT [] +synonym: "hypoglossus" EXACT [] +xref: UBERON:0001650 +is_a: XAO:0000429 ! cranial nerve +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: lab +creation_date: 2011-09-14T10:07:12Z + +[Term] +id: XAO:0004216 +name: glomeral nexus +def: "The narrow bridge that links the two glomera of the pronephric kidney." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000318 ! glomus +relationship: end_stage XAO:1000066 ! NF stage 54 +relationship: part_of XAO:0000318 ! glomus +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: lab +creation_date: 2011-09-14T10:38:02Z + +[Term] +id: XAO:0004217 +name: motor neuron +def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100] +synonym: "motoneuron" EXACT [] +xref: CL:0000100 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T09:25:00Z + +[Term] +id: XAO:0004218 +name: palatoquadrate +def: "The dorsal component of the mandibular arch, the ventral one being Meckel's cartilage. Together with the ceratohyal and connecting musculature, it is responsible for the ventilation and irrigation of the filter apparatus." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000024 ! mandibular crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000097 ! mandibular arch +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: eriksegerdell + +[Term] +id: XAO:0004219 +name: ceratohyal +def: "Cartilaginous element that, together with the palatoquadrate and connecting musculature, is responsible for the ventilation and irrigation of the of the filter apparatus." [XAO:curators] +synonym: "ch" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0000025 ! hyoid crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000098 ! hyoid arch +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell + +[Term] +id: XAO:0004220 +name: anteroventral lateral line placode +def: "Lateral line placode that gives rise to the anteroventral lateral line nerve." [XAO:EJS] +synonym: "anterior ventral lateral line placode" EXACT [] +synonym: "pAV" EXACT [] +is_a: XAO:0000440 ! lateral line placode +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2012-01-27T09:32:47Z + +[Term] +id: XAO:0004221 +name: anterior lateral line placode +def: "Lateral line placode that gives rise to the anterior lateral line nerve." [XAO:EJS] +synonym: "pre-auditory lateral line placode" RELATED [] +is_a: XAO:0000440 ! lateral line placode +relationship: develops_from XAO:0000440 ! lateral line placode +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell + +[Term] +id: XAO:0004222 +name: middle lateral line placode +def: "Lateral line placode that gives rise to the middle lateral line nerve." [XAO:EJS] +synonym: "intermediate lateral line placode" RELATED [] +is_a: XAO:0000440 ! lateral line placode +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell + +[Term] +id: XAO:0004223 +name: posterior lateral line placode +def: "Lateral line placode that gives rise to the posterior lateral line nerve." [XAO:EJS] +synonym: "pP" EXACT [] +synonym: "vagus lateral line placode" RELATED [] +is_a: XAO:0000440 ! lateral line placode +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell + +[Term] +id: XAO:0004224 +name: transporting epithelium +def: "Type of epithelium that facilitates the transcellular transport of solutes. This transport can either be absorption, transport from lumen (apical membrane surface) to blood; or secretion, transport from blood (basolateral membrane surface) to lumen." [http://en.wikipedia.org/wiki/Transcellular_transport] +synonym: "transporting epithelia" RELATED PLURAL [] +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell + +[Term] +id: XAO:0004225 +name: non-ciliated epithelial cell +def: "Type of cell of the epidermis lacking cilia, which separate and space the ciliated epidermal cells." [PMID:16728476] +synonym: "intercalating non-ciliated cell" RELATED [] +synonym: "non-ciliated epithelial cells" RELATED PLURAL [] +is_a: XAO:0003249 ! epithelial cell +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003045 ! epithelium +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell + +[Term] +id: XAO:0004226 +name: ventral tegmentum +def: "Region of the mesencephalon that arises from a small area of the neural plate, spanning the midline immediately adjacent, and being slightly posterior to the dorsal tegmentum area." [PMID:2351962] +synonym: "tegmentum ventrale" EXACT [] +synonym: "ventral brain stem" RELATED [] +synonym: "ventral tegmental area" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell + +[Term] +id: XAO:0004227 +name: dorsal tegmentum +def: "Region of the mesencephalon that arises from a small area of the neural plate immediately adjacent and slightly anterior to the ventral tegmentum area." [PMID:2351962] +synonym: "dorsal brain stem" RELATED [] +synonym: "tegmentum dorsale" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell + +[Term] +id: XAO:0004228 +name: lateral abdominal vein +def: "Laterally located vein that drains the ventral abdominal wall." [ISBN:0815318960] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-01-27T09:37:16Z + +[Term] +id: XAO:0004229 +name: fin crest +def: "The thin epidermis extension of the inner fin visible in the mid trunk region of the inner fin at NF stage 27, and extending posteriorly and then ventrally, ending just before the proctodeum. The fin is more homogeneous in NF stage 46 tadpoles, and the inner fin and fin crest are no longer discrete." [XAO:curators] +is_a: XAO:0003028 ! surface structure +relationship: develops_from XAO:0000004 ! inner fin +relationship: end_stage XAO:1000058 ! NF stage 46 +relationship: part_of XAO:0000028 ! epidermis +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell + +[Term] +id: XAO:0004230 +name: anterior hypothalamus +def: "Anterior part of the hypothalamus, given rise by the midanterior neural ridge along with the chiasmatic ridge during forebrain morphogenesis." [PMID:8537821] +synonym: "alar hypothalamus" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004070 ! hypothalamus +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T09:51:09Z + +[Term] +id: XAO:0004231 +name: barbel +def: "A single long structure at each corner of the mouth that has muscle fibers attached to an internal cartilaginous support and that is mobile." [ISBN:0226557626] +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:1000073 ! NF stage 61 +relationship: start_stage XAO:1000056 ! NF stage 44 +created_by: eriksegerdell + +[Term] +id: XAO:0004232 +name: spiracle +def: "The exit for respiratory water in the tadpole." [ISBN:0226557626] +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell + +[Term] +id: XAO:0004233 +name: truncus arteriosus +def: "A cranial continuation of the bulbis cordis that contains two lateral branches and divides into the carotid arch, systemic arch, and pulmocutaneous arch." [ISBN:0801836018] +is_a: XAO:0001011 ! blood vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: eriksegerdell + +[Term] +id: XAO:0004234 +name: bulbous arteriosis +def: "Multi-tissue structure through which the blood exits the heart. It is a chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches." [XAO:EJS, ZFA:0000173] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell + +[Term] +id: XAO:0004235 +name: manicotto glandulare +def: "The larval stomach." [ISBN:0226893340] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell + +[Term] +id: XAO:0004236 +name: posterior hypothalamus +def: "Posterior part of the hypothalamus, given rise by the midanterior neural plate during forebrain morphogenesis." [PMID:8537821] +synonym: "basal hypothalamus" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004070 ! hypothalamus +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T09:51:49Z + +[Term] +id: XAO:0004237 +name: lateral ganglionic eminence +def: "A distinct elevation of a transient proliferating cell mass of the subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE." [UBERON:0004025] +synonym: "LGE" RELATED [] +xref: UBERON:0004025 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000064 ! NF stage 52 +relationship: part_of XAO:0004258 ! subpallium +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T09:59:19Z + +[Term] +id: XAO:0004238 +name: femur rudiment +def: "A cartilaginous element that is the primordium or commencement of a femur." [XAO:EJS] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: start_stage XAO:1000063 ! NF stage 51 +created_by: eriksegerdell + +[Term] +id: XAO:0004239 +name: hindlimb digit 1 +def: "The most posterior of the hind digits, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ] +synonym: "hallux" RELATED [] +synonym: "hind digit 1" EXACT [] +synonym: "pedal digit 1" EXACT [] +synonym: "toe 1" EXACT [] +synonym: "toe I" EXACT [] +is_a: XAO:0003035 ! hindlimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell + +[Term] +id: XAO:0004240 +name: branchial vein +def: "Type of vein that drains the gill region and which passes backwards lateral to the gill chambers and opens into the pronephric sinus." [ISBN:0815318960] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004241 +name: ischiadic vein +def: "A vein of the hind limb, first visible in the developing hind limb bud at c. NF stage 50 when it enters the ventral commissural vessel." [ISBN:0815318960] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000062 ! NF stage 50 +created_by: eriksegerdell + +[Term] +id: XAO:0004242 +name: ischiadic artery +def: "The accompanying artery of the ischiadic nerve." [http://en.wikipedia.org/wiki/Accompanying_artery_of_ischiadic_nerve] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004243 +name: femoral vein +def: "Either of the primary veins in the hindlimbs that collect blood from the hindlimb region." [AAO:0010237] +synonym: "vena femoralis" RELATED [] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004296 ! hindlimb stylopod +relationship: start_stage XAO:1000063 ! NF stage 51 +created_by: eriksegerdell + +[Term] +id: XAO:0004244 +name: mandibular artery +def: "Part of the lateral pretrosal artery that supplies blood to the roof of the mouth." [AAO:0010496] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell + +[Term] +id: XAO:0004245 +name: maxillary artery +def: "A type of artery that supplies the deep structures of the facial region. It branches from the external carotid artery." [http://en.wikipedia.org/wiki/Maxillary_artery] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell + +[Term] +id: XAO:0004246 +name: rhombomere R7 +def: "The 7th segment of the developing hindbrain." [XAO:EJS] +synonym: "r7" EXACT [] +synonym: "rhombomere 7" EXACT [] +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T10:01:06Z + +[Term] +id: XAO:0004247 +name: vertebral artery +def: "A major artery of the neck that branches from the subclavian arteries and merge to form the single midline basilar artery." [http://en.wikipedia.org/wiki/Vertebral_artery] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004248 +name: epigastric artery +def: "Artery that supplies the anterior wall of the abdomen." [http://medical-dictionary.thefreedictionary.com/epigastric+artery] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004249 +name: renal artery +def: "Artery that supplies blood via branches to the gonads, oviducts, and kidneys." [AAO:0010223] +synonym: "interrenal artery" RELATED [] +is_a: XAO:0000114 ! artery +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000140 ! urogenital system +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004250 +name: facial vein +def: "Vein that collects blood from muscles of the head and drains into the external jugular vein." [AAO:0010513] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004152 ! head vasculature +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell + +[Term] +id: XAO:0004251 +name: cutaneous magnus +def: "Vein that comes from the skin of the trunk." [XAO:EJS] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell + +[Term] +id: XAO:0004252 +name: cutaneous femoral vein +def: "Vein that comes from the subcutaneous tissue of the hindlimb stylopod." [XAO:EJS] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004296 ! hindlimb stylopod +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell + +[Term] +id: XAO:0004253 +name: postcaval vein +def: "One of three major veins that enter the sinus venosus." [AAO:0010506] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000060 ! NF stage 48 +created_by: eriksegerdell + +[Term] +id: XAO:0004254 +name: subclavian vein +def: "Vein that collects blood from the forelimb via the branchial veins and from the muscles and skin of the trunk via the anterior epigastric and lateral veins." [AAO:0010510] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000060 ! NF stage 48 +created_by: eriksegerdell +creation_date: 2012-01-28T05:08:21Z + +[Term] +id: XAO:0004255 +name: lateral vein +def: "Either of the veins that collect blood from the trunk and skin and drain into the subclavian vein." [AAO:0010515] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell + +[Term] +id: XAO:0004256 +name: ventral abdominal vein +def: "A vein formed by the combination of veins in the pelvic region that collects blood from the liver, stomach, intestines, and gall bladder." [AAO:0010517] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004423 ! trunk vasculature +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell + +[Term] +id: XAO:0004257 +name: Jacobson's vein +def: "Vein that drains Jacobson's organ." [XAO:curators] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell + +[Term] +id: XAO:0004258 +name: subpallium +def: "Structure that comprises the base region of the telencephalon." [UBERON:0000204] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell + +[Term] +id: XAO:0004259 +name: medial ganglionic eminence +def: "A distinct elevation of a transient proliferating cell mass of the subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE." [UBERON:0004024] +synonym: "MGE" EXACT [] +xref: UBERON:0004024 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000064 ! NF stage 52 +relationship: part_of XAO:0004258 ! subpallium +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell + +[Term] +id: XAO:0004260 +name: pharyngeal pouch +def: "Any of the outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits." [TAO:0001106, XAO:EJS] +synonym: "pharyngeal pouches" RELATED PLURAL [] +xref: UBERON:0004117 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004463 ! pharyngeal endoderm +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: eriksegerdell + +[Term] +id: XAO:0004261 +name: pharyngeal region +def: "Region encompassing the oral end of the alimentary canal." [XAO:EJS] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell + +[Term] +id: XAO:0004262 +name: ventral caudal lymphatic vessel +def: "Lymphatic vessel located in the posterior ventral region of the trunk, ventral to the posterior cardinal vein." [PMID:9048122465] +synonym: "VCLV" EXACT [] +is_a: XAO:0000375 ! lymph vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell + +[Term] +id: XAO:0004263 +name: stylopod +def: "Limb segment that is the proximal part of the limb (i.e. the humerus of the forelimb, and the femur of the hindlimb, and surrounding tissues)." [UBERON:0002472] +synonym: "mesopodium" EXACT [] +synonym: "stylopodium" EXACT [] +xref: UBERON:0002472 +is_a: XAO:0004294 ! limb segment +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell + +[Term] +id: XAO:0004264 +name: zeugopod +def: "Limb segment that is the middle part of the limb (i.e. the radio-ulna of the forelimb, and the tarsus and tibia-fibula of the hindlimb, and surrounding tissues)." [UBERON:0002471] +synonym: "metapodium" EXACT [] +synonym: "zeugopodium" EXACT [] +xref: UBERON:0002471 +is_a: XAO:0004294 ! limb segment +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell + +[Term] +id: XAO:0004265 +name: autopod +def: "Limb segment that is the terminal part of the limb (i.e. the metacarpels and phalanges of the forelimb, and the metatarsals and phalanges of the hindlimb, and surrounding tissues)." [XAO:curators] +synonym: "acropodium" EXACT [] +synonym: "autopodium" EXACT [] +is_a: XAO:0004294 ! limb segment +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell + +[Term] +id: XAO:0004266 +name: rhombomere R8 +def: "The 8th and most posterior segment of the developing hindbrain." [XAO:EJS] +synonym: "r8" EXACT [] +synonym: "rhombomere 8" EXACT [] +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-27T10:01:21Z + +[Term] +id: XAO:0004267 +name: interneuron +def: "A multipolar neuron that connects afferent neurons and efferent neurons in neural pathways. They are found within the central nervous system and enteric nervous system." [http://en.wikipedia.org/wiki/Interneuron] +xref: CL:0000099 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005195 ! enteric nervous system +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2012-01-27T10:24:56Z + +[Term] +id: XAO:0004268 +name: posterior lateral line +def: "A lateral line that extends from the ear in a posterior-ventral direction." [PMID:2652193] +is_a: XAO:0004002 ! lateral line +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell + +[Term] +id: XAO:0004269 +name: anterodorsal lateral line placode +def: "Lateral line placode that gives rise to the anterodorsal lateral line nerve." [XAO:EJS] +synonym: "anterior dorsal lateral line placode" EXACT [] +synonym: "antero-dorsal lateral line placode" EXACT [] +synonym: "pAD" EXACT [] +is_a: XAO:0000440 ! lateral line placode +relationship: develops_from XAO:0004206 ! anterior placodal area +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell + +[Term] +id: XAO:0004270 +name: hepato-pancreatic progenitor cell +def: "Any of a field of cells in the posterior section of the foregut that will give rise to the liver bud and dorsal and ventral pancreatic buds." [XAO:curators] +synonym: "hepato-pancreatic progenitor cells" RELATED PLURAL [] +is_a: XAO:0005033 ! progenitor cell +relationship: develops_from XAO:0000090 ! endoderm +relationship: develops_from XAO:0000101 ! liver diverticulum +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell + +[Term] +id: XAO:0004271 +name: midbrain tegmentum +def: "Multi-tissue structure that is the ventral part of the midbrain." [UBERON:0001943] +synonym: "Tegm" EXACT [] +synonym: "tegmentum" RELATED [] +synonym: "tegmentum mesencephali" EXACT [] +synonym: "ventral midbrain" RELATED [] +xref: UBERON:0001943 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-01-28T06:06:15Z + +[Term] +id: XAO:0004272 +name: migrating neuroblast +def: "Any of the neuronal precursor cells that are isolated and scattered throughout the anterior ventro-lateral region of the embryo, generally in a punctate pattern, immediately below the ectoderm." [PMID:17554687, XAO:curators] +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000057 ! NF stage 45 +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2012-02-08T12:22:41Z + +[Term] +id: XAO:0004274 +name: articular system +def: "Anatomical system that consists of all the joints of the body." [UBERON:0004770] +synonym: "joint system" EXACT [] +xref: UBERON:0004770 +is_a: XAO:0003002 ! anatomical system +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003060 ! skeletal system +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0004275 +name: axial ossicle +def: "Ossicle that is part of the axial skeleton." [UBERON:0011142] +synonym: "vertebral ossicle" RELATED [] +xref: UBERON:0011142 +is_a: XAO:0004193 ! ossicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003073 ! postcranial axial skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004276 +name: bone element +def: "Skeletal element that is composed of bone tissue." [UBERON:0001474] +synonym: "bone" RELATED [] +synonym: "bone organ" EXACT [] +xref: UBERON:0001474 +is_a: XAO:0004012 ! skeletal element +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004277 +name: caudal fin skeleton +def: "Median fin skeleton supporting the caudal fin." [VSAO:0000167] +is_a: XAO:0004282 ! median fin skeleton +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004062 ! tail fin +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004278 +name: coracoid bone +def: "Paired bone that is part of the shoulder assembly, joining the scapula to the front end of the sternum." [http://en.wikipedia.org/wiki/Coracoid] +synonym: "coracoid" RELATED [] +xref: UBERON:0004743 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003063 ! pectoral girdle +relationship: start_stage XAO:1000070 ! NF stage 58 + +[Term] +id: XAO:0004279 +name: cranial skeleton +def: "Skeletal subdivision of the head that includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [VSAO:0000049] +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004011 ! axial skeleton +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004280 +name: dorsal fin skeleton +def: "Median fin skeleton located on the dorsal surface of the organism." [VSAO:0000168] +is_a: XAO:0004282 ! median fin skeleton +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004063 ! dorsal fin +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004281 +name: median fin +def: "Fin that is an unpaired fin located in the sagittal plane of the organism." [VSAO:0000162] +is_a: XAO:0000002 ! fin +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0004282 +name: median fin skeleton +def: "Postcranial axial skeleton that is unpaired and located on the sagittal plane of the organism." [VSAO:0000170] +synonym: "axial fin skeleton" EXACT [] +synonym: "unpaired fin skeleton" EXACT [] +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004281 ! median fin +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004283 +name: paired appendage +def: "Appendage that is one of the anterior or posterior paired appendages (i.e. the forelimbs and hindlimbs)." [XAO:EJS] +is_a: XAO:0000218 ! appendage +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0004284 +name: pectoral appendage +def: "Appendage that is one of the anterior paired appendages (i.e. the forelimbs)." [XAO:EJS] +synonym: "anterior paired appendage" EXACT [] +is_a: XAO:0004283 ! paired appendage +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0004285 +name: pelvic appendage +def: "Appendage that is one of the posterior paired appendages (i.e. the hindlimbs)." [XAO:EJS] +synonym: "posterior paired appendage" EXACT [] +is_a: XAO:0004283 ! paired appendage +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0004286 +name: scapula +def: "Bone that forms the posterior part of the pectoral (shoulder) girdle." [http://en.wikipedia.org/wiki/Scapula] +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003063 ! pectoral girdle +relationship: start_stage XAO:1000072 ! NF stage 60 + +[Term] +id: XAO:0004287 +name: vertebral centrum +def: "Skeletal element that surrounds the notochord." [VSAO:0000183] +synonym: "centrum" RELATED [] +is_a: XAO:0004012 ! skeletal element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004288 ! vertebral element +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004288 +name: vertebral element +def: "Skeletal element that forms around the notochord and is part of the vertebral column." [UBERON:0010913] +xref: UBERON:0010913 +is_a: XAO:0004012 ! skeletal element +relationship: develops_from XAO:0000397 ! sclerotome +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003074 ! vertebral column +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0004289 +name: skeletal subdivision +def: "Anatomical cluster consisting of the skeletal elements that are part of the skeleton." [VSAO:0000042] +synonym: "subdivision of skeleton" EXACT [] +xref: UBERON:0010912 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004053 ! skeleton +relationship: start_stage XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:0004290 +name: cell part +def: "Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher." [CARO:0000014] +synonym: "cell component" EXACT [] +xref: CARO:0000014 +xref: GO:0044464 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003012 ! cell +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2012-02-23T11:17:28Z + +[Term] +id: XAO:0004291 +name: cell-free extract +namespace: xenopus_anatomy_in_vitro +def: "A solution obtained by rupturing cells (especially unfertilized oocytes) and removing all particulate matter." [http://medical-dictionary.thefreedictionary.com/cell-free+extract] +synonym: "cell-free extracts" RELATED PLURAL [] +is_a: XAO:0003007 ! anatomical entity in vitro +created_by: eriksegerdell +creation_date: 2012-03-10T01:20:30Z + +[Term] +id: XAO:0004292 +name: wedge region +def: "Region of the oocyte vegetal cortex that contains a subdomain of ER organized on top of the mitochondrial cloud and where localization of Vg1 mRNA takes place." [PMID:15654016] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000085 ! oocyte stage III +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000084 ! oocyte stage II +created_by: eriksegerdell +creation_date: 2012-03-10T01:46:15Z + +[Term] +id: XAO:0004293 +name: ring structure +def: "Contractile ring formed at the division plane of the oocyte during first cleavage." [PMID:11942608] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000085 ! oocyte stage III +created_by: eriksegerdell +creation_date: 2012-03-10T01:47:35Z + +[Term] +id: XAO:0004294 +name: limb segment +def: "A major subdivision of a limb." [UBERON:0002529] +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003027 ! limb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T02:08:16Z + +[Term] +id: XAO:0004295 +name: forelimb stylopod +def: "Stylopod (the limb segment closest to the body) that is part of a forelimb." [UBERON:0003822] +synonym: "upper arm" EXACT [] +is_a: XAO:0004263 ! stylopod +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003030 ! forelimb +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2012-03-10T02:21:56Z + +[Term] +id: XAO:0004296 +name: hindlimb stylopod +def: "Stylopod (the limb segment closet to the body) that is part of a hindlimb." [XAO:curators] +synonym: "upper leg" EXACT [] +is_a: XAO:0004263 ! stylopod +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T02:22:26Z + +[Term] +id: XAO:0004297 +name: forelimb zeugopod +def: "Limb segment that is the middle part of the forelimb (i.e. the radio-ulna and surrounding tissues)." [XAO:CJZ] +is_a: XAO:0004264 ! zeugopod +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003030 ! forelimb +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2012-03-10T02:29:57Z + +[Term] +id: XAO:0004298 +name: hindlimb zeugopod +def: "Limb segment that is the middle part of the hindlimb (i.e. the tarsus and tibia-fibula and surrounding tissues)." [UBERON:0003823] +is_a: XAO:0004264 ! zeugopod +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T02:30:08Z + +[Term] +id: XAO:0004299 +name: hand +def: "Terminal portion of a forelimb." [UBERON:0002398] +synonym: "front foot" EXACT [] +is_a: XAO:0004265 ! autopod +relationship: develops_from XAO:0004490 ! forelimb bud tip +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003030 ! forelimb +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2012-03-10T02:45:33Z + +[Term] +id: XAO:0004300 +name: foot +def: "Terminal portion of a hindlimb that bears weight and allows locomotion." [UBERON:0002387] +synonym: "hind foot" EXACT [] +is_a: XAO:0004265 ! autopod +relationship: develops_from XAO:0004491 ! hindlimb bud tip +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T02:45:35Z + +[Term] +id: XAO:0004301 +name: eminentia thalami +def: "Part of the diencephalon that is located between the prethalamus, hypothalamus, and the telencephalon." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T03:15:31Z + +[Term] +id: XAO:0004302 +name: pallium +def: "Structure that comprises the roof region of the telencephalon." [UBERON:0000203] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T03:21:58Z + +[Term] +id: XAO:0004303 +name: pretectum +def: "Multi-tissue structure that is the dorsal part of the diencephalon and the major sensory input to which is visual." [XAO:EJS, ZFA:0000418] +synonym: "P1" RELATED [] +synonym: "prosomere 1" RELATED [] +synonym: "PT" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000024 ! NF stage 14 +created_by: eriksegerdell +creation_date: 2012-03-10T03:28:09Z + +[Term] +id: XAO:0004304 +name: prethalamus +def: "Multi-tissue structure forming the anterior part of the diencephalon and lying between the thalamus, hypothalamus, and eminentia thalami." [XAO:EJS] +synonym: "P3" RELATED [] +synonym: "prosomere 3" RELATED [] +synonym: "PTh" EXACT [] +synonym: "subthalamus" RELATED [] +synonym: "ventral thalamus" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T03:34:32Z + +[Term] +id: XAO:0004305 +name: zona limitans intrathalamica +def: "A narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon." [UBERON:0009848] +synonym: "Zli" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T03:39:28Z + +[Term] +id: XAO:0004306 +name: thalamus +def: "A midline paired symmetrical structure within the brain; the main product of the embryonic diencephalon." [UBERON:0001897] +synonym: "Th" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T03:44:52Z + +[Term] +id: XAO:0004307 +name: head mesenchyme +def: "Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head." [XAO:EJS, ZFA:0000113] +synonym: "cephalic mesenchyme" RELATED [] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-03-10T04:21:21Z + +[Term] +id: XAO:0004308 +name: glial cell +def: "Any of the non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain, and for neurons in other parts of the nervous system such as in the autonomic nervous system. Neural crest derived." [XAO:CJZ] +synonym: "glia" RELATED PLURAL [] +synonym: "glial cells" RELATED PLURAL [] +synonym: "neuroglia" RELATED PLURAL [] +synonym: "neuroglial cells" RELATED PLURAL [] +xref: CL:0000125 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-03-10T09:44:35Z + +[Term] +id: XAO:0004309 +name: postmigratory neural crest cell +def: "Any of the cells that are of neural crest origin, now in place in their postmigratory target tissues, such as the sciatic nerve, dorsal root ganglia, gut or skin. They can be visualised or detected by specific molecular markers." [XAO:CJZ] +synonym: "postmigratory neural crest cells" RELATED PLURAL [] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-03-10T09:50:34Z + +[Term] +id: XAO:0004310 +name: stapes +def: "Bone of the ear that is connected to the tympanic membrane via the extrastapes. This structure is the amphibian ear ossicle, also known as the columella. It extends between extrastapes cartilage and the oval window. The extrastapes forms a cartilaginous tympanic disk." [ISBN:0520252780, XAO:curators] +synonym: "columella" RELATED [] +is_a: XAO:0000214 ! auditory ossicle +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000191 ! middle ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2012-03-10T10:07:32Z + +[Term] +id: XAO:0004311 +name: regenerating limb +def: "A portion of limb tissue that is re-growing after damage or amputation." [XAO:EJS] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T10:08:56Z + +[Term] +id: XAO:0004312 +name: regenerating fin +def: "A portion of fin tissue that is re-growing after damage or amputation." [XAO:EJS] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000041 ! NF stage 25 +created_by: eriksegerdell +creation_date: 2012-03-10T10:10:26Z + +[Term] +id: XAO:0004313 +name: joint region +def: "Anatomical region at which two or more bones make contact and that includes some of the surrounding tissues of various types." [XAO:CJZ] +synonym: "joint" RELATED [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-03-10T10:13:09Z + +[Term] +id: XAO:0004314 +name: digit-joint region +def: "A joint region within a digit, one of several most distal parts of a limb." [XAO:EJS] +is_a: XAO:0004313 ! joint region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003032 ! digit +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T10:14:19Z + +[Term] +id: XAO:0004315 +name: perichondrial cell +def: "A cell of the perichondrium, the fibrous membrane of connective tissue covering the surface of cartilage." [http://medical-dictionary.thefreedictionary.com/Perichondrial] +synonym: "perichondrial cells" RELATED PLURAL [] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004049 ! perichondrium +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2012-03-10T10:15:02Z + +[Term] +id: XAO:0004316 +name: interdigital region +def: "Anatomical region between digits, the most distal parts of a limb." [XAO:curators] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-03-10T10:16:20Z + +[Term] +id: XAO:0004317 +name: amputated tissue +def: "A portion of tissue that has been removed from the body." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2012-03-10T10:19:48Z + +[Term] +id: XAO:0004318 +name: amputated fin +def: "A portion of fin tissue that has been removed from the body." [XAO:EJS] +is_a: XAO:0004317 ! amputated tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000041 ! NF stage 25 +created_by: eriksegerdell +creation_date: 2012-03-10T10:22:32Z + +[Term] +id: XAO:0004319 +name: amputated limb +def: "A portion of limb tissue that has been removed from the body." [XAO:EJS] +is_a: XAO:0004317 ! amputated tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-03-10T10:23:05Z + +[Term] +id: XAO:0004320 +name: mesenchymal stem cell +def: "Multipotent stromal cell that can differentiate into a variety of cell types, including: osteoblasts/osteocytes (bone cells), chondroblasts/chondrocytes (cartilage cells), and adipoblasts/adipocytes (fat cells)." [XAO:curators] +synonym: "mesenchymal cell" RELATED [] +synonym: "mesenchymal stem cells" RELATED PLURAL [] +is_a: XAO:0003054 ! stem cell +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2012-03-10T11:14:06Z + +[Term] +id: XAO:0004321 +name: dorsal caudal lymphatic vessel +def: "Lymphatic vessel located in the posterior dorsal region of the trunk." [XAO:EJS] +synonym: "DCLV" EXACT [] +is_a: XAO:0000375 ! lymph vessel +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-03-25T03:48:38Z + +[Term] +id: XAO:0004322 +name: cranial muscle +def: "Any of the muscles that are part of the head." [XAO:curators] +synonym: "head muscle" RELATED [] +is_a: XAO:0000172 ! muscle +relationship: develops_from XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004323 +name: mandibular head muscle +def: "Any of the paired mandibular arch muscles." [PMID:21050205] +is_a: XAO:0004322 ! cranial muscle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004324 +name: hyoid head muscle +def: "Any of the bilateral hyoid arch muscles innervated by cranial nerve VII." [PMID:21050205] +is_a: XAO:0004322 ! cranial muscle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004325 +name: branchial head muscle +def: "Any of the muscles that support the filigreed structure of the gill basket necessary for filter feeding, through the stabilisation, extension and compression of the gill basket." [PMID:21050205] +is_a: XAO:0004322 ! cranial muscle +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004326 +name: hypobranchial head muscle +def: "Straplike muscle that arises from elements of the pectoral girdle and passes to the hyoid bone and laryngeal cartilages." [http://www.britannica.com/EBchecked/topic/279858/hypobranchial-muscle] +is_a: XAO:0004322 ! cranial muscle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004327 +name: eye muscle +def: "A muscle that is part of the eye region and controls the movement of the eye." [UBERON:0004277] +is_a: XAO:0004322 ! cranial muscle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004328 +name: m. levator mandibulae longus internus +def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. It separates medially from levator mandibulae longus supeficialis, with which it shares a common origin." [PMID:17624928] +synonym: "mlmli" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004425 ! m. levator mandibulae longus internus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004329 +name: m. levator mandibulae longus profundus +def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. After separating from levator mandibulae longus superficialis, it parallels it and inserts in the connective tissue. Only at later stages, its rostral third is slightly curved laterally and inserts in the region of the anlage of the tentacular cartilage." [PMID:17624928] +synonym: "mlmlp" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004426 ! m. levator mandibulae longus profundus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004330 +name: m. levator mandibulae longus superficialis +def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. The first mandibular arch muscle to appear, it originates ventral to the center of the eye, and extends rostroventrally to end lateral to the buccal cavity." [PMID:17624928] +synonym: "mlmls" EXACT [] +synonym: "superior long mandibular levator muscle" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004427 ! m. levator mandibulae longus superior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004331 +name: m. levator mandibulae articularis +def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. It originates from the ventral bend of the anlage of processus muscularis palatoquadrati. It runs ventrally near the levator mandibulae longus supeficialis and inserts anterior of it at Meckel's cartilage." [PMID:17624928] +synonym: "articularis mandibular levator muscle" EXACT [] +synonym: "mlma" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004428 ! m. levator mandibulae articularis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004332 +name: m. levator mandibulae externus +def: "Muscle that is part a complex that arises from the skull roof and acts to elevate or close the lower jaw. The last jaw levator to develop, it originates rostral to the palatoquadrate." [PMID:17624928] +synonym: "external mandibular levator muscle" EXACT [] +synonym: "mlme" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004429 ! m. levator mandibulae externus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004333 +name: m. intermandibularis +def: "Ventral muscle of the larval head that is a broad transverse sheet lying between the Meckel's cartilages and joining its opposite mid-ventrally in an median raphe." [http://jcs.biologists.org/content/s2-81/322/161] +synonym: "intermandibular muscle" EXACT [] +synonym: "mim" EXACT [] +is_a: XAO:0004323 ! mandibular head muscle +relationship: develops_from XAO:0004430 ! m. intermandibularis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004334 +name: m. quadrato-hyoangularis +def: "Hyoid arch muscle that connects Meckel's cartilage with the palatoquadrate and supports the opening of the mouth by depressing Meckel's cartilage." [PMID:21050205] +synonym: "mqh" EXACT [] +synonym: "quadrato-hyoangularis muscle" EXACT [] +is_a: XAO:0004324 ! hyoid head muscle +relationship: develops_from XAO:0004431 ! m. quadrato-hyoangularis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004335 +name: m. orbitohyoideus +def: "Large, tapering muscle that originates on the muscular process and inserts on the ceratohyal." [ISBN:0226557626] +synonym: "moh" EXACT [] +synonym: "orbitohyoidal muscle" EXACT [] +is_a: XAO:0004324 ! hyoid head muscle +relationship: develops_from XAO:0004432 ! m. orbitohyoideus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004336 +name: m. interhyoideus +def: "A thin curved muscle located between the ceratohyal cartilages." [PMID:21050205] +synonym: "interhyoidal muscle" EXACT [] +synonym: "mih" EXACT [] +is_a: XAO:0004324 ! hyoid head muscle +relationship: develops_from XAO:0004433 ! m. interhyoideus primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004337 +name: m. subarcualis rectus I +def: "Deep, visceral muscle associated with tongue movement." [AAO:0010659] +synonym: "msr" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004434 ! m. subarcualis rectus I primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004338 +name: m. transversus anterior +def: "Muscle situated between the planum hypobranchiale and the basihyobranchial, presumably to stabilize the connection between these elements." [PMID:17624928] +synonym: "mta" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004435 ! m. transversus anterior primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004339 +name: m. transversus ventralis II +def: "Muscle that springs from the second branchial arch, meeting its opposite in a mid-ventral raphe." [http://jcs.biologists.org/content/s2-81/322/161] +synonym: "mtvII" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004436 ! m. transversus ventralis II primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004340 +name: mm. levator arcuum branchialium I +def: "The 1st branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS] +synonym: "mlabI" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004437 ! mm. levator arcuum branchialium I primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004341 +name: mm. levator arcuum branchialium II +def: "The 2nd branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS] +synonym: "mlabII" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004438 ! mm. levator arcuum branchialium II primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004342 +name: mm. levator arcuum branchialium III +def: "The 3rd branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS] +synonym: "mlabIII" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004439 ! mm. levator arcuum branchialium III primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004343 +name: mm. levator arcuum branchialium IV +def: "The 4th branchial levator muscle, which contributes to raising the branchial apparatus." [XAO:EJS] +synonym: "mlabIV" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004440 ! mm. levator arcuum branchialium IV primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004344 +name: mm. constrictores branchiales II +def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It originates on the ventrolateral process of the palatoquadrate." [http://jcs.biologists.org/content/s2-81/322/161] +synonym: "mcbII" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004441 ! mm. constrictores branchiales II primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004345 +name: mm. constrictores branchiales III +def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It is located on the crista parotica and commissura branchio-cranialis." [http://jcs.biologists.org/content/s2-81/322/161] +synonym: "mcbIII" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004442 ! mm. constrictores branchiales III primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004346 +name: mm. constrictores branchiales IV +def: "Muscle that arises on part of the chondrocranium and passes to the ventro-lateral region of the cerato-branchialia. It is a small muscle situated at the posterior end of the branchial skeleton." [http://jcs.biologists.org/content/s2-81/322/161] +synonym: "mcbIV" EXACT [] +is_a: XAO:0004325 ! branchial head muscle +relationship: develops_from XAO:0004443 ! mm. constrictores branchiales IV primordium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004349 +name: m. constrictor laryngis +def: "Muscle that consists of dorsal and ventral parts that arise from medial raphe and insert on the arytenoid cartilages." [ISBN:0226557626] +is_a: XAO:0004351 ! laryngeal muscle +relationship: develops_from XAO:0004446 ! m. constrictor laryngis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004350 +name: m. dilatator laryngis +def: "Muscle that arises from the edge of levator arcus branchialis IV and inserts on the arytenoid cartilage and the cricoid ring." [ISBN:0226557626] +is_a: XAO:0004351 ! laryngeal muscle +relationship: develops_from XAO:0004447 ! m. dilatator laryngis primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004351 +name: laryngeal muscle +def: "Type of muscle that attaches to the larynx." [XAO:EJS] +synonym: "LM" EXACT [] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0004448 ! laryngeal muscle primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000054 ! NF stage 42 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004352 +name: m. rectus anterior +def: "Muscle in the orbit that inserts on the anterior side of the eye and the function of which is adduction of the eyeball." [XAO:curators] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004449 ! m. rectus anterior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004353 +name: m. rectus posterior +def: "Muscle in the orbit that inserts on the posterior side of the eye and the function of which is adduction of the eyeball." [XAO:curators] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004450 ! m. rectus posterior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004354 +name: m. rectus inferior +def: "Muscle in the orbit that depresses, adducts, and helps extort (rotate laterally) the eye." [UBERON:0006322] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004451 ! m. rectus inferior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004355 +name: m. rectus superior +def: "Muscle in the orbit, the primary function is of which is elevation." [UBERON:0006323] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004452 ! m. rectus superior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004356 +name: m. obliquus inferior +def: "Thin, narrow muscle placed near the anterior margin of the floor of the orbit." [UBERON:0006320] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004453 ! m. obliquus inferior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004357 +name: m. obliquus superior +def: "Muscle in the upper, medial side of the orbit whose primary action is downward, lateral rotation of the eye." [UBERON:0006321] +is_a: XAO:0004327 ! eye muscle +relationship: develops_from XAO:0004454 ! m. obliquus superior primordium +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004358 +name: basihyal +alt_id: XAO:0004382 +def: "Cartilaginous element that is median and is the anterior-most cartilage of the ventral hyoid arch." [UBERON:0011615] +synonym: "basihyobranchial" EXACT [] +synonym: "bhb" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004359 +name: ceratobranchial I +def: "The cartilaginous element below the epibranchial in branchial arch 1." [http://www.thefreedictionary.com/Ceratobranchial] +synonym: "cbl-I" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004360 +name: ceratobranchial II +def: "The cartilaginous element below the epibranchial in branchial arch 2." [http://www.thefreedictionary.com/Ceratobranchial] +synonym: "cbl-II" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004361 +name: ceratobranchial III +def: "The cartilaginous element below the epibranchial in branchial arch 3." [http://www.thefreedictionary.com/Ceratobranchial] +synonym: "cbl-III" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004362 +name: ceratobranchial IV +def: "The cartilaginous element below the epibranchial in branchial arch 4." [http://www.thefreedictionary.com/Ceratobranchial] +synonym: "cbl-IV" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004363 +name: commisura quadratocranialis anterior +def: "Cartilaginous element comprising the rostral connection of the palatoquadrate cartilage to the neurocranium." [PMID:21050205] +synonym: "cqca" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004364 +name: cornua trabecula +def: "Cartilaginous element that supports the anterior end of the nasal organ." [ISBN:1276806469] +synonym: "cornua trabeculae" RELATED PLURAL [] +synonym: "ct" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004365 +name: fenestra basicranialis +def: "The space where the trabeculae of the tadpole chondrocranium have not yet fused." [ISBN:0226557626] +synonym: "fbc" EXACT [] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004366 +name: facies hyoidis of the palatoquadrate +def: "One of the cartilaginous surfaces of the tadpole jaw." [XAO:curators] +synonym: "fhpq" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004367 +name: fenestra subocularis +def: "The wide gap that separates the palatoquadrate from the neurocranium." [ISBN:0226557626] +synonym: "fso" EXACT [] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004368 +name: infrarostral +def: "Cartilaginous element comprising cartilages that articulate with Meckel's cartilage in the lower jaw and are fused medially." [PMID:21050205] +synonym: "io" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004369 +name: processus anterior hyalis +def: "Cartilaginous element comprising the anterior process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205] +synonym: "pach" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004370 +name: processus articularis palatoquadrati +def: "Cartilaginous element comprising the articular process that forms the jaw joint with the posterior end of Meckel's cartilage." [ISBN:0226557626] +synonym: "parpq" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004371 +name: processus ascendens palatoquadrate +def: "Cartilaginous element comprising the ascending process that helps anchor the larval palatoquadrate to the neurocranium." [ISBN:0226557626] +synonym: "paspq" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004372 +name: parachordal +def: "Rod-shaped paired cartilages located on either side of the notochord and involved in the formation of the base of the chondrochranium." [TAO:0001423, XAO:EJS] +synonym: "parachordal cartilage" RELATED [] +synonym: "pk" EXACT [] +xref: UBERON:0009635 +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004373 +name: processus lateralis hyalis +def: "Cartilaginous element comprising the lateral process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205] +synonym: "plch" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004374 +name: planum hypobranchiale +alt_id: XAO:0004383 +def: "One of the cartilaginous elements that meet and articulate in the median plane posterior to the basibranchial." [http://amphibiatree.org/node/407] +synonym: "plana hypobranchiale" RELATED PLURAL [] +synonym: "plhb" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004375 +name: planum trabeculare anticum +def: "Cartilaginous element that is posterior to the cornua trabeculae." [XAO:curators] +synonym: "ethmoid plate" RELATED [] +synonym: "planum ethmoidale" RELATED [] +synonym: "plta" EXACT [] +synonym: "trabecular plate" RELATED [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004376 +name: processus muscularis palatoquadrati +def: "Cartilaginous element comprising the muscular process, a flattened triangular process that is the site of attachment for the orbitohyoideus and suspensoriohyoideus muscles." [ISBN:0226557626] +synonym: "pmpq" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004377 +name: processus posterior hyalis +def: "Cartilaginous element comprising the posterior process of ceratohyal cartilage derived from the hyoid neural crest stream." [PMID:21050205] +synonym: "ppch" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004378 +name: palatoquadrati +def: "Cartilaginous element comprising the dorsal component of the mandibular arch." [UBERON:0004752] +synonym: "palatoquadrate cartilage" EXACT [] +synonym: "pq" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004379 +name: processus retroarticularis of Meckel's cartilage +def: "Cartilaginous element that forms at the posteroventral tip of Meckel's cartilage." [XAO:EJS, ZFA:0000422] +synonym: "prmc" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: part_of XAO:0003085 ! Meckel's cartilage +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004380 +name: suprarostral plate +def: "Cartilaginous element that comprises a crescent-shaped plate that supports the tentacular cartilage in the upper jaw." [PMID:21050205] +synonym: "sp" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004381 +name: trabecula cranii +def: "Cartilaginous element comprising a pair of chondrification centers in the base of the embryonic cartilaginous neurocranium." [http://www.medilexicon.com/medicaldictionary.php?t=92818] +synonym: "tc" EXACT [] +synonym: "trabeculae cranii" RELATED PLURAL [] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004384 +name: peripheral vegetal yolk mass +def: "Peripherally located part of the vegetal cell mass of prospective endoderm." [XAO:EJS] +synonym: "peripheral vegetal cell mass" EXACT [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000281 ! vegetal yolk mass +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2012-05-31T02:56:10Z + +[Term] +id: XAO:0004385 +name: branchial basket +alt_id: XAO:0004386 +def: "Cartilaginous element that comprises the network-like cartilaginous skeleton of the gill region." [UBERON:0009119] +synonym: "gill basket" EXACT [] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004387 +name: retinal stem cell region +def: "Region of the ciliary marginal zone, at the edge (most distal region) where retinal stem cells are located." [PMID:7695895] +synonym: "ciliary marginal zone stem cell region" EXACT [] +synonym: "CMZ stem cell region" EXACT [] +synonym: "RSCR" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000086 ! ciliary marginal zone +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004388 +name: retinal progenitor cell region +def: "Region of the ciliary marginal zone where retinal progenitor cells are located." [PMID:7695895] +synonym: "ciliary marginal zone progenitor cell region" EXACT [] +synonym: "CMZ progenitor cell region" EXACT [] +synonym: "RPCR" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000086 ! ciliary marginal zone +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004389 +name: oculomotor motornucleus +def: "Ganglion in the midbrain that gives rise to the fibers of the oculomotor nerve." [XAO:KAB] +synonym: "oculomotor nucleus" RELATED [] +synonym: "OM" EXACT [] +xref: UBERON:0001715 +is_a: XAO:0004609 ! neural nucleus +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: part_of XAO:0000027 ! cranial ganglion +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004390 +name: dorsal thalamus +def: "Multi-tissue structure that is the dorsal part of the thalamus and emerges ventral to the caudal portion of the ventral habenular nucleus." [XAO:EJS, ZFA:0000653] +synonym: "DT" EXACT [] +synonym: "epithalamus" RELATED [] +synonym: "P2" RELATED [] +synonym: "prosomere 2" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004391 +name: trochlear motornucleus +def: "The nucleus of the trochlear nerve (cranial nerve IV)." [XAO:EJS] +synonym: "TM" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004392 +name: goblet cell +def: "A type of mucus surface cell in the tadpole." [ISBN:080184780X] +synonym: "goblet cells" RELATED PLURAL [] +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004393 +name: mucociliary epithelium +def: "Type of epithelium in the embryonic epidermis that is mucus-secreting and ciliated." [XAO:curators] +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000028 ! epidermis +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004394 +name: hatching gland primordium +def: "The presumptive cells of the hatching gland, present by the end of gastrulation." [XAO:EJS] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0004091 ! non-neural ectoderm +relationship: end_stage XAO:1000024 ! NF stage 14 +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004395 +name: central vegetal yolk mass +def: "Centrally located part of the vegetal cell mass of prospective endoderm." [XAO:EJS] +synonym: "central vegetal cell mass" EXACT [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: part_of XAO:0000281 ! vegetal yolk mass +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2012-05-31T02:57:12Z + +[Term] +id: XAO:0004396 +name: apical mesenchyme +def: "Regenerating tissue consisting of mesenchyme cells at the tip of the regenerating limb." [XAO:EJS] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004397 +name: wound epidermis +def: "A layer of epidermal cells that initially covers the surface of an amputation site. Fibroblasts from the surrounding connective tissue migrate across the amputation surface to meet at the center of the wound. These fibroblasts multiply to form a blastema, which are the progenitors for the new limb." [XAO:CJZ] +synonym: "apical wound epidermis" RELATED [] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004398 +name: wound epidermis inner layer +def: "Regenerating tissue that forms the inner or basal layer of wound epidermis." [XAO:EJS] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004397 ! wound epidermis +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004399 +name: wound epidermis outer layer +def: "Regenerating tissue that forms the outer layer of wound epidermis." [XAO:EJS] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004397 ! wound epidermis +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004400 +name: regenerating zeugopod skeleton +def: "Tissue consisting of a cartilaginous rod or rods of a regenerating zeugopod segment of a limb." [XAO:curators] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: part_of XAO:0004311 ! regenerating limb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004401 +name: apical epithelial cap +def: "A layer of signaling cells at the apex of a regenerating blastema, which has a vital role in regeneration." [XAO:CJZ] +synonym: "AEC" EXACT [] +is_a: XAO:0004059 ! regenerating tissue +relationship: develops_from XAO:0004397 ! wound epidermis +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004402 +name: pseudoblastema +def: "Following amputation in late prometamorphosis or in young froglets, tissue comprising fibroblast-like cells in a limb stump that aggregate beneath the wound epithelia." [ISBN:3540228713] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004403 +name: fibrocellular pad +def: "Regenerative tissue that develops and covers cut bone in the tadpole." [PMID:10906786] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004404 +name: keratinocyte +def: "The predominant cell type in the epidermis, the primary function of which is the formation of a barrier against environmental damage." [http://en.wikipedia.org/wiki/Keratinocyte] +synonym: "keratinocytes" RELATED PLURAL [] +is_a: XAO:0003252 ! keratin accumulating cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004405 +name: Leydig cell +def: "A type of special epithelial cell that secretes mucus into the subsurface extracellular compartments of the epidermis." [ISBN:080184780X] +synonym: "Leydig cells" RELATED PLURAL [] +synonym: "Leydig gland cell" RELATED [] +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000028 ! epidermis +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004406 +name: presumptive axial mesoderm +def: "Presumptive structure that will develop into axial mesoderm." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000072 ! dorsal marginal zone +relationship: develops_from XAO:0000083 ! involuted dorsal mesoderm +relationship: end_stage XAO:1000033 ! NF stage 12.5 +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004407 +name: proximal mesenchyme +def: "Mesenchyme that occupies the proximal region of a limb bud." [XAO:EJS] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004408 +name: anterior-proximal mesenchyme +def: "Mesenchyme that occupies the anterior proximal region of a limb bud." [XAO:EJS] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004409 +name: posterior-proximal mesenchyme +def: "Mesenchyme that occupies the posterior proximal region of a limb bud." [XAO:EJS] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004410 +name: interdigital mesenchyme +def: "Mesenchyme that occupies the interdigital region of a limb bud." [XAO:EJS] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000068 ! NF stage 56 +relationship: part_of XAO:0003161 ! limb bud +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004411 +name: lateral line primordium +def: "Portion of tissue that migrates and deposits immature neuromasts and interneuromasts." [XAO:EJS, ZFA:0000228] +is_a: XAO:0003043 ! primordium +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000095 ! lateral line system +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2012-05-31T08:03:05Z + +[Term] +id: XAO:0004412 +name: hindlimb digit 2 +def: "The 2nd most posterior of the hind digits, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ] +synonym: "hind digit 2" EXACT [] +synonym: "pedal digit 2" EXACT [] +synonym: "toe 2" EXACT [] +synonym: "toe II" EXACT [] +is_a: XAO:0003035 ! hindlimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004413 +name: hindlimb digit 3 +def: "The 3rd most posterior, or middle, of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "hind digit 3" EXACT [] +synonym: "pedal digit 3" EXACT [] +synonym: "toe 3" EXACT [] +synonym: "toe III" EXACT [] +is_a: XAO:0003035 ! hindlimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004414 +name: hindlimb digit 4 +def: "The 2nd most anterior of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "hind digit 4" EXACT [] +synonym: "pedal digit 4" EXACT [] +synonym: "toe 4" EXACT [] +synonym: "toe IV" EXACT [] +is_a: XAO:0003035 ! hindlimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004415 +name: hindlimb digit 5 +def: "The most anterior and longest of the hind digits, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "hind digit 5" EXACT [] +synonym: "pedal digit 5" EXACT [] +synonym: "toe 5" EXACT [] +synonym: "toe V" EXACT [] +is_a: XAO:0003035 ! hindlimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004416 +name: claw primordium +def: "Portion of tissue consisting of unkeratinized cells at the most distal end of a developing digit and which will become a claw." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000069 ! NF stage 57 +relationship: part_of XAO:0003035 ! hindlimb digit +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004417 +name: claw of hindlimb digit 1 +def: "Claw located at the end of the 1st hindlimb digit." [XAO:EJS] +synonym: "claw of hind digit 1" EXACT [] +is_a: XAO:0003103 ! claw +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004239 ! hindlimb digit 1 +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004418 +name: claw of hindlimb digit 2 +def: "Claw located at the end of the 2nd hindlimb digit." [XAO:EJS] +synonym: "claw of hind digit 2" EXACT [] +is_a: XAO:0003103 ! claw +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004412 ! hindlimb digit 2 +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004419 +name: claw of hindlimb digit 3 +def: "Claw located at the end of the 3rd hindlimb digit." [XAO:EJS] +synonym: "claw of hind digit 3" EXACT [] +is_a: XAO:0003103 ! claw +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004413 ! hindlimb digit 3 +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004420 +name: claw of hindlimb digit 4 +def: "Claw located at the end of the 4th hindlimb digit." [XAO:EJS] +synonym: "claw of hind digit 4" EXACT [] +is_a: XAO:0003103 ! claw +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004414 ! hindlimb digit 4 +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004421 +name: claw of hindlimb digit 5 +def: "Claw located at the end of the 5th hindlimb digit." [XAO:EJS] +synonym: "claw of hind digit 5" EXACT [] +is_a: XAO:0003103 ! claw +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004415 ! hindlimb digit 5 +relationship: start_stage XAO:1000070 ! NF stage 58 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004422 +name: posterior lateral line ganglion +def: "Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate the posterior lateral line system." [XAO:EJS, ZFA:0001314] +synonym: "posterior lateral line ganglia" RELATED PLURAL [] +is_a: XAO:0004457 ! lateral line ganglion +relationship: develops_from XAO:0004223 ! posterior lateral line placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2012-05-05T05:15:00Z + +[Term] +id: XAO:0004423 +name: trunk vasculature +def: "The blood vessels of the trunk region." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000100 ! cardiovascular system +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000035 ! NF stage 19 +created_by: eriksegerdell +creation_date: 2012-05-26T05:47:10Z + +[Term] +id: XAO:0004424 +name: central retina +def: "Anatomical region comprising the central part of the retina." [XAO:EJS] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2012-07-01T02:33:21Z + +[Term] +id: XAO:0004425 +name: m. levator mandibulae longus internus primordium +def: "The presumptive cells of the levator mandibulae longus internus muscle." [XAO:EJS] +synonym: "mlmli" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004426 +name: m. levator mandibulae longus profundus primordium +def: "The presumptive cells of the levator mandibulae longus profundus muscle." [XAO:EJS] +synonym: "mlmlp" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004427 +name: m. levator mandibulae longus superior primordium +def: "The presumptive cells of the levator mandibulae longus superior muscle." [XAO:EJS] +synonym: "mlmls" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004428 +name: m. levator mandibulae articularis primordium +def: "The presumptive cells of the levator mandibulae articularis muscle." [XAO:EJS] +synonym: "mlma" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004429 +name: m. levator mandibulae externus primordium +def: "The presumptive cells of the levator mandibulae externus muscle." [XAO:EJS] +synonym: "mlme" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000057 ! NF stage 45 +relationship: start_stage XAO:1000056 ! NF stage 44 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004430 +name: m. intermandibularis primordium +def: "The presumptive cells of the intermandibularis muscle." [XAO:EJS] +synonym: "mim" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004431 +name: m. quadrato-hyoangularis primordium +def: "The presumptive cells of the quadrato-hyoangularis muscle." [XAO:EJS] +synonym: "mqh" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004432 +name: m. orbitohyoideus primordium +def: "The presumptive cells of the orbitohyoideus muscle." [XAO:EJS] +synonym: "moh" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004433 +name: m. interhyoideus primordium +def: "The presumptive cells of the interhyoideus muscle." [XAO:EJS] +synonym: "mih" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004434 +name: m. subarcualis rectus I primordium +def: "The presumptive cells of the subarcualis rectus I muscle." [XAO:EJS] +synonym: "msr" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004435 +name: m. transversus anterior primordium +def: "The presumptive cells of the transversus anterior muscle." [XAO:EJS] +synonym: "mta" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004436 +name: m. transversus ventralis II primordium +def: "The presumptive cells of the transversus ventralis II muscle." [XAO:EJS] +synonym: "mtvII" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004437 +name: mm. levator arcuum branchialium I primordium +def: "The presumptive cells of the levator arcuum branchialium I muscles." [XAO:EJS] +synonym: "mlabI" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004438 +name: mm. levator arcuum branchialium II primordium +def: "The presumptive cells of the levator arcuum branchialium II muscles." [XAO:EJS] +synonym: "mlabII" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004439 +name: mm. levator arcuum branchialium III primordium +def: "The presumptive cells of the levator arcuum branchialium III muscles." [XAO:EJS] +synonym: "mlabIII" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004440 +name: mm. levator arcuum branchialium IV primordium +def: "The presumptive cells of the levator arcuum branchialium IV muscles." [XAO:EJS] +synonym: "mlabIV" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004441 +name: mm. constrictores branchiales II primordium +def: "The presumptive cells of the constrictores branchiales II muscles." [XAO:EJS] +synonym: "mcbII" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004442 +name: mm. constrictores branchiales III primordium +def: "The presumptive cells of the constrictores branchiales III muscles." [XAO:EJS] +synonym: "mcbIII" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004443 +name: mm. constrictores branchiales IV primordium +def: "The presumptive cells of the constrictores branchiales IV muscles." [XAO:EJS] +synonym: "mcbIV" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004444 +name: m. geniohyoideus primordium +def: "The presumptive cells of the geniohyoideus muscle." [XAO:EJS] +synonym: "mgh" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004445 +name: m. rectus cervicis primordium +def: "The presumptive cells of the rectus cervicis muscle." [XAO:EJS] +synonym: "mrc" RELATED [] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004446 +name: m. constrictor laryngis primordium +def: "The presumptive cells of the constrictor laryngis muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004447 +name: m. dilatator laryngis primordium +def: "The presumptive cells of the dilatator laryngis muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004448 +name: laryngeal muscle primordium +def: "The presumptive cells of laryngeal muscle." [XAO:EJS] +is_a: XAO:0003043 ! primordium +relationship: end_stage XAO:1000053 ! NF stage 41 +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004449 +name: m. rectus anterior primordium +def: "The presumptive cells of the rectus anterior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004450 +name: m. rectus posterior primordium +def: "The presumptive cells of the rectus posterior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004451 +name: m. rectus inferior primordium +def: "The presumptive cells of the rectus inferior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004452 +name: m. rectus superior primordium +def: "The presumptive cells of the rectus superior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004453 +name: m. obliquus inferior primordium +def: "The presumptive cells of the obliquus inferior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004454 +name: m. obliquus superior primordium +def: "The presumptive cells of the obliquus superior muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T09:49:00Z + +[Term] +id: XAO:0004455 +name: cranial muscle primordium +def: "The presumptive cells of any of the cranial muscles." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:1000057 ! NF stage 45 +relationship: part_of XAO:0004042 ! muscular system +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2012-05-30T10:00:01Z + +[Term] +id: XAO:0004456 +name: Brachet's cleft +def: "A sharp boundary, running parallel to the outside of the embryo, between involuted mesoderm and external ectoderm. It runs from the blastopore to the upper limit of the involuted mesoderm." [PMID:21464931] +synonym: "Brachy's cleft" EXACT [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000037 ! NF stage 21 +relationship: start_stage XAO:1000021 ! NF stage 11 +created_by: eriksegerdell +creation_date: 2012-05-31T11:43:41Z + +[Term] +id: XAO:0004457 +name: lateral line ganglion +def: "Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate a lateral line." [XAO:EJS, ZFA:0000120] +synonym: "lateral line ganglia" RELATED PLURAL [] +is_a: XAO:0000027 ! cranial ganglion +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000095 ! lateral line system +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2012-05-31T08:16:22Z + +[Term] +id: XAO:0004458 +name: peripheral retina +def: "Anatomical region comprising the peripheral part of the retina." [XAO:EJS] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2012-07-01T02:33:47Z + +[Term] +id: XAO:0004459 +name: subocular cartilage +def: "Cartilaginous element that is below the trabecula and parachordal." [XAO:curators] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0003205 ! chondrocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2012-09-09T03:24:03Z + +[Term] +id: XAO:0004460 +name: choroid +def: "Portion of tissue comprising the vascular layer of the eye, containing connective tissue and lying between the retina and the sclera. It provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, it forms the uveal tract." [http://en.wikipedia.org/wiki/Choroid, XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: part_of XAO:0004529 ! uveal tract +relationship: start_stage XAO:1000056 ! NF stage 44 +created_by: eriksegerdell +creation_date: 2012-09-09T03:31:52Z + +[Term] +id: XAO:0004461 +name: circumpharyngeal ridge +def: "Site above the branchial arch complex where vagal neural crest cells temporarily arrest their migration before entering the pharyngeal arches and heart." [XAO:curators] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0004191 ! vagal neural crest +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-09-09T03:40:23Z + +[Term] +id: XAO:0004462 +name: dorsal endoderm +def: "Single cell layer of involuted endoderm lying beneath the prechordal plate." [XAO:curators] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0000094 ! gastrocoel roof plate +relationship: start_stage XAO:1000021 ! NF stage 11 +created_by: eriksegerdell +creation_date: 2012-09-09T03:50:45Z + +[Term] +id: XAO:0004463 +name: pharyngeal endoderm +def: "Embryonic endoderm that evaginates to form the paired pharyngeal pouches." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000090 ! endoderm +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2012-09-09T04:08:58Z + +[Term] +id: XAO:0004464 +name: rhombomere R1 +def: "The most anterior segment of the developing hindbrain." [XAO:curators] +synonym: "r1" EXACT [] +synonym: "rhombomere 1" RELATED [] +is_a: XAO:0004079 ! rhombomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2012-09-09T04:24:23Z + +[Term] +id: XAO:0004465 +name: endolymphatic duct +def: "Canal that connects the membranous labyrinth of the ear with the endolymphatic sac." [http://medical-dictionary.thefreedictionary.com/endolymphatic+duct] +is_a: XAO:0004000 ! duct +relationship: develops_from XAO:0000196 ! sacculus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2012-09-09T04:31:49Z + +[Term] +id: XAO:0004466 +name: serous membrane +def: "Multi-tissue structure that comprises a secretory epithelial layer and a connective tissue layer." [http://en.wikipedia.org/wiki/Serous_membrane] +synonym: "serosa" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2012-09-18T03:32:10Z + +[Term] +id: XAO:0004467 +name: zygote cortex +def: "Cell component comprising the outer layers of the zygote." [XAO:EJS] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: part_of XAO:0000035 ! zygote +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2012-09-18T03:50:25Z + +[Term] +id: XAO:0004468 +name: organ cortex +def: "Multi-tissue structure that is the outermost layer of an organ." [UBERON:0001851] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 +created_by: eriksegerdell +creation_date: 2012-09-18T03:51:06Z + +[Term] +id: XAO:0004469 +name: trabecula +def: "A small tissue element in the form of a beam, strut, or rod that generally has a mechanical function and is usually composed of dense cartilaginous tissue." [http://en.wikipedia.org/wiki/Trabecula] +synonym: "trabeculae" RELATED PLURAL [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0004470 +name: trabecula carnea +def: "A type of trabecula that consists of a rounded or irregular column that projects from the inner surface of the ventricle of the heart." [http://en.wikipedia.org/wiki/Trabeculae_carneae] +synonym: "trabeculae carneae" RELATED PLURAL [] +is_a: XAO:0004469 ! trabecula +relationship: develops_from XAO:0000065 ! myocardium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:0004471 +name: atrial septum +def: "Cardiac septum that separates the right atrium from the left atrium." [UBERON:0002085] +is_a: XAO:0005422 ! septum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0004472 +name: sinus venosus +def: "A large quadrangular cavity that precedes the atrium on the venous side of the heart." [http://en.wikipedia.org/wiki/Sinus_venosus] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0004473 +name: ventral mesoderm +def: "Embryonic structure that is induced by the organizer to become lateral mesoderm." [http://en.wikipedia.org/wiki/Regional_specification] +xref: UBERON:2000083 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000084 ! involuted ventral mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2013-03-15T20:23:49Z + +[Term] +id: XAO:0004474 +name: periotic region +def: "Anatomical region that surrounds the otic vesicle." [XAO:curators] +synonym: "periotic mesenchyme" RELATED [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000070 ! NF stage 58 +relationship: part_of XAO:0000040 ! head region +relationship: start_stage XAO:1000041 ! NF stage 25 +created_by: eriksegerdell +creation_date: 2013-03-17T11:59:34Z + +[Term] +id: XAO:0004475 +name: myocyte +def: "A mature contractile cell, which has as part of its cytoplasm myofibrils organized in various patterns. Found in muscle tissue, myocytes are long, tubular cells that arise developmentally from myoblasts to form muscle. There are specialized forms: cardiac, skeletal, and smooth muscle myocytes, with various properties." [CL:0000187, XAO:curators] +synonym: "muscle cell" RELATED [] +synonym: "muscle cells" RELATED PLURAL [] +synonym: "muscle fiber" RELATED [] +synonym: "myocytes" RELATED PLURAL [] +xref: CL:0000187 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0003015 ! myoblast +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000172 ! muscle +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: eriksegerdell +creation_date: 2013-03-17T12:20:58Z + +[Term] +id: XAO:0004476 +name: skeletal myocyte +def: "A myocyte of the skeletal muscle." [XAO:curators] +synonym: "skeletal muscle cell" RELATED [] +synonym: "skeletal muscle cells" RELATED PLURAL [] +synonym: "skeletal myocytes" RELATED PLURAL [] +xref: CL:0000188 +is_a: XAO:0004475 ! myocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000174 ! skeletal muscle +relationship: start_stage XAO:1000058 ! NF stage 46 +created_by: eriksegerdell +creation_date: 2013-03-17T12:44:10Z + +[Term] +id: XAO:0004477 +name: smooth muscle myocyte +def: "A myocyte of the smooth muscle." [XAO:curators] +synonym: "smooth muscle cell" RELATED [] +synonym: "smooth muscle cells" RELATED PLURAL [] +synonym: "smooth muscle myocytes" RELATED PLURAL [] +xref: CL:0000192 +is_a: XAO:0004475 ! myocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000175 ! smooth muscle +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: eriksegerdell +creation_date: 2013-03-17T12:44:35Z + +[Term] +id: XAO:0004478 +name: forelimb digit 2 +def: "The most posterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "fore digit 2" EXACT [] +synonym: "manual digit 2" EXACT [] +is_a: XAO:0003036 ! forelimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2013-03-17T13:50:37Z + +[Term] +id: XAO:0004479 +name: forelimb digit 3 +def: "The second most posterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "fore digit 3" EXACT [] +synonym: "manual digit 3" EXACT [] +is_a: XAO:0003036 ! forelimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2013-03-17T13:50:40Z + +[Term] +id: XAO:0004480 +name: forelimb digit 4 +def: "The second most anterior digit of a forelimb, consisting of a single metatarsal, 3 phalanges, and a claw." [XAO:CJZ] +synonym: "fore digit 4" EXACT [] +synonym: "manual digit 4" EXACT [] +is_a: XAO:0003036 ! forelimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2013-03-17T13:50:49Z + +[Term] +id: XAO:0004481 +name: forelimb digit 5 +def: "The most anterior digit of a forelimb, consisting of a single metatarsal, 2 phalanges, and a claw." [XAO:CJZ] +synonym: "fore digit 5" EXACT [] +synonym: "manual digit 5" EXACT [] +is_a: XAO:0003036 ! forelimb digit +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2013-03-17T13:50:51Z + +[Term] +id: XAO:0004482 +name: epicardial precursor cell +def: "Neural crest-derived cell type that gives rise to the epicardium." [XAO:curators] +synonym: "epicardial precursor cells" RELATED PLURAL [] +synonym: "pro-epicardial organ" RELATED [] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000064 ! heart +relationship: part_of XAO:0005062 ! proepicardium +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2013-04-10T12:31:30Z + +[Term] +id: XAO:0004483 +name: retinal stem cell +def: "Cell that is present in the stem cell region of the retinal ciliary marginal zone." [XAO:CJZ] +synonym: "retinal stem cells" RELATED PLURAL [] +is_a: XAO:0003054 ! stem cell +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004387 ! retinal stem cell region +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2013-04-10T12:52:47Z + +[Term] +id: XAO:0004484 +name: retinal progenitor cell +def: "Cell that is present in the progenitor cell region of the retinal ciliary marginal zone." [XAO:CJZ] +synonym: "retinal progenitor cells" RELATED PLURAL [] +is_a: XAO:0005033 ! progenitor cell +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004388 ! retinal progenitor cell region +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2013-04-10T12:57:10Z + +[Term] +id: XAO:0004485 +name: neuroendocrine cell +def: "An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals." [CL:0000165] +synonym: "neuroendocrine cells" RELATED PLURAL [] +xref: CL:0000165 +is_a: XAO:0003247 ! endocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell +creation_date: 2013-04-10T13:03:39Z + +[Term] +id: XAO:0004486 +name: organ part +def: "Anatomical structure that has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement." [UBERON:0000064] +xref: UBERON:0000064 +is_a: XAO:0003000 ! anatomical structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000037 ! NF stage 21 +created_by: eriksegerdell +creation_date: 2013-04-10T13:51:44Z + +[Term] +id: XAO:0004487 +name: epiphysis +def: "Organ part consisting of the rounded end of a long bone (at its joint with adjacent bone), which in Xenopus are the tibia-fibula and femur of the hindlimb, and the radio-ulna and humerus of the forelimb." [XAO:CJZ] +is_a: XAO:0004486 ! organ part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003209 ! radio-ulna +relationship: part_of XAO:0003210 ! humerus +relationship: part_of XAO:0003213 ! tibia-fibula +relationship: part_of XAO:0003214 ! femur +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2013-04-10T13:54:10Z + +[Term] +id: XAO:0004488 +name: diaphysis +def: "Organ part consisting of the main section or midsection of a long bone, which in Xenopus are the tibia-fibula and femur of the hindlimb, and the radio-ulna and humerus of the forelimb." [XAO:CJZ] +is_a: XAO:0004486 ! organ part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003209 ! radio-ulna +relationship: part_of XAO:0003210 ! humerus +relationship: part_of XAO:0003213 ! tibia-fibula +relationship: part_of XAO:0003214 ! femur +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2013-04-10T14:00:23Z + +[Term] +id: XAO:0004489 +name: spike +def: "A cone-shaped hypomorphic structure consisting of a single continuous cartilage, typical of a regenerated forelimb or hindlimb when amputated after a specific developmental stage." [XAO:CJZ] +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004311 ! regenerating limb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2013-04-10T14:06:57Z + +[Term] +id: XAO:0004490 +name: forelimb bud tip +def: "The apical region of a developing forelimb bud which will form the autopod segment of the forelimb." [XAO:CJZ] +synonym: "presumptive forelimb autopodium" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0003065 ! forelimb bud +relationship: start_stage XAO:1000060 ! NF stage 48 +created_by: eriksegerdell +creation_date: 2013-04-10T15:11:00Z + +[Term] +id: XAO:0004491 +name: hindlimb bud tip +def: "The apical region of a developing hindlimb bud which will form the autopod segment of the hindlimb." [XAO:CJZ] +synonym: "presumptive hindlimb autopodium" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0003066 ! hindlimb bud +relationship: start_stage XAO:1000060 ! NF stage 48 +created_by: eriksegerdell +creation_date: 2013-04-10T15:23:29Z + +[Term] +id: XAO:0004492 +name: cleavage furrow +def: "The physical groove that forms between cells at the first cell division. One-celled oocytes (NF stage 1) undergo cytoplasmic reorganization driven by sperm entry in the animal pole, where the cleavage furrow initiates, and it moves circumferentially along a line of longitude as well as progressing inwards through the cytoplasm, ultimately dividing the fertilized oocyte into two cells of equal size, defining NF stage 2." [PMID:11891298, PMID:16371595, XAO:CJZ] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000001 ! NF stage 1 +relationship: start_stage XAO:1000092 ! mature egg stage +created_by: eriksegerdell +creation_date: 2013-04-10T15:39:26Z + +[Term] +id: XAO:0004493 +name: pelvic girdle primordium +def: "The presumptive cells of the pelvic girdle." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:1000066 ! NF stage 54 +relationship: start_stage XAO:1000065 ! NF stage 53 +created_by: eriksegerdell +creation_date: 2013-04-10T18:41:04Z + +[Term] +id: XAO:0004494 +name: iliac process +def: "A prominent, slender, rod-like projection of the iliac bone located close to the acetabiulum and directed posteriorly." [XAO:CJZ] +is_a: XAO:0004020 ! process +relationship: develops_from XAO:0004495 ! iliac process primordium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004496 ! ilium +relationship: start_stage XAO:1000066 ! NF stage 54 +created_by: eriksegerdell +creation_date: 2013-04-10T18:45:25Z + +[Term] +id: XAO:0004495 +name: iliac process primordium +def: "The presumptive cells of the iliac process." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:1000065 ! NF stage 53 +relationship: start_stage XAO:1000065 ! NF stage 53 +created_by: eriksegerdell +creation_date: 2013-04-10T18:49:21Z + +[Term] +id: XAO:0004496 +name: ilium +def: "Either of the paired bones that are the dorsal-most and largest bones of the pelvic girdle. They begin to connect to the sacral vertebra (9th vertebra) at NF stage 59." [XAO:CJZ] +synonym: "ilia" RELATED PLURAL [] +synonym: "iliac bone" EXACT [] +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003064 ! pelvic girdle +relationship: start_stage XAO:1000066 ! NF stage 54 +created_by: eriksegerdell +creation_date: 2013-04-10T18:56:57Z + +[Term] +id: XAO:0004497 +name: ischium +def: "Any of the posterior and smaller bones of the pelvic girdle. The ischia appear at NF stage 53, grow toward each other at NF stage 55, fusing and beginning to ossify by NF stage 58/59." [XAO:CJZ] +synonym: "ischia" RELATED PLURAL [] +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003064 ! pelvic girdle +relationship: start_stage XAO:1000066 ! NF stage 54 +created_by: eriksegerdell +creation_date: 2013-04-10T19:03:50Z + +[Term] +id: XAO:0004498 +name: pubis +def: "The ventral and anterior of the three principal bones composing the pelvic girdle. The pubes fuse with the ilia at NF stage 53, and touch each other at NF stage 62. Full contact of the medial surfaces occurs at NF stage 63 when ossification also begins. Ossification continues through metamorphosis." [PMID:15679868, XAO:CJZ] +synonym: "pubes" RELATED PLURAL [] +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003064 ! pelvic girdle +relationship: start_stage XAO:1000065 ! NF stage 53 +created_by: eriksegerdell +creation_date: 2013-04-10T19:18:02Z + +[Term] +id: XAO:0004499 +name: postsacral vertebra +def: "Vertebra posterior to the sacral vertebra. The 4 postsacral vertebrae fuse and ossify (NF stage 66) to form the urostyle." [XAO:CJZ] +synonym: "postsacral vertebrae" RELATED PLURAL [] +is_a: XAO:0004019 ! vertebra +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000060 ! NF stage 48 +created_by: eriksegerdell +creation_date: 2013-04-10T19:27:34Z + +[Term] +id: XAO:0004500 +name: rib +def: "Any of the bony lateral projections from the presacral veterebrae of the anterior trunk region, enabling the lungs to expand and thus facilitate breathing by expanding the chest cavity. They serve to protect the lungs, heart, and other internal organs of the thorax." [http://en.wikipedia.org/wiki/Rib] +synonym: "ribs" RELATED PLURAL [] +synonym: "vertebral rib" EXACT [] +is_a: XAO:0004020 ! process +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004019 ! vertebra +relationship: start_stage XAO:1000064 ! NF stage 52 +created_by: eriksegerdell +creation_date: 2013-04-10T19:32:29Z + +[Term] +id: XAO:0004501 +name: apoptotic cell +def: "A cell that is in the process of programmed cell death. The process is characterized by morphological changes (e.g. blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, and chromosomal DNA fragmentation) ending in cell death." [http://en.wikipedia.org/wiki/Apoptosis] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2013-04-10T19:46:34Z + +[Term] +id: XAO:0004502 +name: mitotic cell +def: "A cell that is in the process of replication, and is idenitifable by chromosomal replication." [XAO:curators] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2013-04-10T19:50:41Z + +[Term] +id: XAO:0004503 +name: periosteum +def: "A membrane that lines the outer surface of all bones, except at the joints of long bones. It consists of dense irregular connective tissue, and is divided into an outer fibrous layer and inner osteogenic layer. The fibrous layer contains fibroblasts, while the osteogenic layer contains progenitor cells that develop into osteoblasts, which are essential to the healing process." [http://en.wikipedia.org/wiki/Periosteum] +is_a: XAO:0001017 ! connective tissue +relationship: develops_from XAO:0004049 ! perichondrium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000169 ! bone tissue +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2013-04-10T19:57:52Z + +[Term] +id: XAO:0004504 +name: periosteum (sensu fibrous layer) +def: "The outer layer of the periosteum, containing acellular connective tissue and fibroblasts." [http://en.wikipedia.org/wiki/Periosteum] +is_a: XAO:0001017 ! connective tissue +relationship: develops_from XAO:0004049 ! perichondrium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004503 ! periosteum +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2013-04-10T20:03:11Z + +[Term] +id: XAO:0004505 +name: periosteum (sensu osteogenic layer) +def: "The inner layer of the periosteum, containing osteoblasts." [http://en.wikipedia.org/wiki/Periosteum] +is_a: XAO:0001017 ! connective tissue +relationship: develops_from XAO:0004049 ! perichondrium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004503 ! periosteum +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2013-04-10T20:03:49Z + +[Term] +id: XAO:0004506 +name: interdigital webbing +def: "The tissue or tissues between the digits of the forelimb and the hindlimb." [XAO:curators] +synonym: "webbing" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004265 ! autopod +relationship: part_of XAO:0004316 ! interdigital region +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2013-04-10T20:14:47Z + +[Term] +id: XAO:0004507 +name: osteoblast +def: "Skeletogenic cell that secretes osteoid, is capable of producing mineralized matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell." [CL:0000062] +synonym: "bone cell" RELATED [] +xref: CL:0000062 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004035 ! osteoid +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2013-04-10T20:18:46Z + +[Term] +id: XAO:0004508 +name: mandibular mesenchyme +def: "Mesenchyme that is part of a mandibular component." [UBERON:0009584] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004279 ! cranial skeleton +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2013-04-10T22:47:54Z + +[Term] +id: XAO:0004509 +name: dorsal lateral plate mesoderm +def: "Layer of lateral plate mesoderm that forms the body wall lining and dermis." [http://en.wikipedia.org/wiki/Lateral_plate_mesoderm] +synonym: "DLPM" EXACT [] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000311 ! lateral plate mesoderm +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2013-04-10T23:01:12Z + +[Term] +id: XAO:0004510 +name: melanoblast +def: "Type of precursor cell from which melanophores develop." [XAO:CJZ] +xref: CL:0000541 +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell +creation_date: 2013-04-10T23:08:51Z + +[Term] +id: XAO:0004511 +name: hindgut primordium +def: "The endoderm cells that are fated to become the hindgut." [XAO:CJZ] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000295 ! central endoderm +relationship: end_stage XAO:1000035 ! NF stage 19 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000026 ! NF stage 16 +created_by: eriksegerdell +creation_date: 2013-04-10T23:24:26Z + +[Term] +id: XAO:0004512 +name: midgut primordium +def: "The endoderm cells that are fated to become the midgut." [XAO:CJZ] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000295 ! central endoderm +relationship: end_stage XAO:1000035 ! NF stage 19 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000026 ! NF stage 16 +created_by: eriksegerdell +creation_date: 2013-04-10T23:31:07Z + +[Term] +id: XAO:0004513 +name: foregut endoderm +def: "The endoderm cells that are fated to become the foregut." [XAO:CJZ] +synonym: "foregut primordium" RELATED [] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000295 ! central endoderm +relationship: end_stage XAO:1000051 ! NF stage 39 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000024 ! NF stage 14 +created_by: eriksegerdell +creation_date: 2013-04-10T23:32:46Z + +[Term] +id: XAO:0004514 +name: anterior tectum +def: "The anterior part of the optic tectum." [XAO:EJS] +synonym: "pre-tectum" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003226 ! optic tectum +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2013-04-10T23:41:35Z + +[Term] +id: XAO:0004515 +name: posterior tectum +def: "The posterior part of the optic tectum." [XAO:EJS] +synonym: "pre-tectum" RELATED [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003226 ! optic tectum +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2013-04-10T23:43:45Z + +[Term] +id: XAO:0004516 +name: blastocoel floor +def: "The upper surface of the vegetal yolk mass which forms the floor for the blastocoel (cavity) of the early gastrula embryo." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000023 ! NF stage 13 +relationship: part_of XAO:0000294 ! blastocoel +relationship: start_stage XAO:1000017 ! NF stage 7 +created_by: eriksegerdell +creation_date: 2013-04-10T23:45:26Z + +[Term] +id: XAO:0004517 +name: ciliated non-epidermal cell +def: "A ciliated cell that is not part of the epidermis." [XAO:EJS] +is_a: XAO:0005017 ! ciliated cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2013-04-11T11:36:47Z + +[Term] +id: XAO:0004518 +name: proximal tubule +def: "The proximal segment of the pronephric tubule, closest to the glomus and functioning in solute resorption and waste excretion." [PMID:15223337] +synonym: "pronephric nephron" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004105 ! pronephric tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2013-04-26T14:20:27Z + +[Term] +id: XAO:0004519 +name: distal tubule +def: "The distal segment of the pronephric tubule, functioning in water resorption, with urine passing through it into the pronephric duct." [PMID:15223337] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004105 ! pronephric tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2013-04-26T14:34:59Z + +[Term] +id: XAO:0004520 +name: proximal tubule branch +def: "A distal stem cell region of the proximal tubule. There are 3 branches, with anteriodorsal, anterioventral, and posterior positions. These are sometimes referred to as proximal tubule segment 1 or PT1." [XAO:CJZ] +synonym: "proximal tubule segment 1" RELATED [] +synonym: "PT1" RELATED [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: part_of XAO:0004518 ! proximal tubule +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2013-04-26T14:48:46Z + +[Term] +id: XAO:0004521 +name: coelom +def: "A fluid-filled cavity formed within the mesoderm of the embryo." [http://en.wikipedia.org/wiki/Coelom] +synonym: "body cavity" RELATED [] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000113 ! embryo +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000035 ! NF stage 19 +created_by: eriksegerdell +creation_date: 2013-04-26T15:36:18Z + +[Term] +id: XAO:0004522 +name: premigratory neural crest cell +def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration." [CL:0007004] +synonym: "premigratory neural crest cells" RELATED PLURAL [] +xref: CL:0007004 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2013-05-27T16:31:38Z + +[Term] +id: XAO:0004523 +name: enteric neuron +def: "Any of the neurons specific to the gastrointestinal system. Enteric neurons are embedded the lining of the esophagus, stomach, small and large intestines and the cloaca." [https://en.wikipedia.org/wiki/Enteric_nervous_system] +xref: CL:0007011 +is_a: XAO:0003023 ! neuron +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000104 ! hindgut +relationship: part_of XAO:0000130 ! small intestine +relationship: part_of XAO:0000131 ! large intestine +relationship: part_of XAO:0000244 ! cloaca +relationship: part_of XAO:0005195 ! enteric nervous system +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2013-05-27T16:58:52Z + +[Term] +id: XAO:0004524 +name: pharyngeal mesenchyme +def: "The undifferentiated, loose connective tissue of the pharyngeal region, that is derived mostly from mesoderm, and also contains ectodermally derived neural crest cells." [XAO:CJZ] +is_a: XAO:0003046 ! mesenchyme +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004261 ! pharyngeal region +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0004525 +name: medium cavity +def: "Water-filled cavity in the adult frog that is apposed to an olfactory epithelium for detection of aqueous odorants." [XAO:KAB] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000078 ! NF stage 66 + +[Term] +id: XAO:0004526 +name: principal cavity +def: "Air-filled cavity in the adult frog apposed to an olfactory epithelium for detection of airborne odorants." [XAO:KAB] +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000078 ! NF stage 66 + +[Term] +id: XAO:0004527 +name: olfactory sensory neuron +def: "Sensory neuron responsible for detection of odorants." [XAO:KAB] +synonym: "olfactory receptor neuron" EXACT [] +synonym: "ORN" EXACT [] +synonym: "OSN" EXACT [] +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005024 ! olfactory epithelium +relationship: start_stage XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:0004528 +name: tail somite 18 +def: "The 16th somite located posterior to the head. This somite is resorbed at metamorphosis." [XAO:EJS] +synonym: "somite 18" EXACT [] +synonym: "trunk somite 18" EXACT [] +is_a: XAO:0003143 ! tail somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0004529 +name: uveal tract +def: "Portion of tissue in an eye consisting of the iris, ciliary body, and choroid." [UBERON:0001768] +synonym: "uvea" EXACT [] +xref: UBERON:0001768 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:0004530 +name: accessory olfactory bulb +def: "The forebrain region that coordinates sensory signaling arising from the vomeronasal organ; it is located on the dorsal-posterior portion of the main olfactory bulb, and the axons that leave the accessory olfactory bulb project to targets in the amygdala and hypothalamus." [UBERON:0004069] +synonym: "anterior olfactory bulb" RELATED [] +xref: UBERON:0004069 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004180 ! olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004531 +name: amygdala +def: "An almond-shaped set of neurons in the medial temporal lobe of the brain that is involved in the linkage of environmental information with social behavior and action selection." [GO:0021764, PMID:24005304] +synonym: "Amyg" EXACT [] +synonym: "corpus amygdaloideum" RELATED [] +xref: UBERON:0001876 +is_a: XAO:0003160 ! anatomical cluster +relationship: develops_from XAO:0004258 ! subpallium +relationship: develops_from XAO:0004563 ! lateral pallium +relationship: develops_from XAO:0004594 ! ventral pallium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004539 ! basal forebrain +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004532 +name: anterior amygdala +def: "A nucleus comprising the anterior aspect of the amygdala, adjacent to the basal forebrain, and involved in receiving olfactory information." [ISBN:0123815339] +xref: UBERON:0002890 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004531 ! amygdala +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004533 +name: anterior commissure +def: "A forebrain white matter structure consisting of a large fiber bundle, connecting the two cerebral hemispheres across the middle line." [XAO:KAB] +synonym: "AC" EXACT [] +xref: UBERON:0000935 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004534 +name: anterior entopeduncular nucleus +def: "Nucleus situated in the pallidum that provides auditory input to the torus semicircularis." [PMID:11536185] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004578 ! pallidum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004535 +name: ventral funiculus +def: "Region of spinal cord white matter lying on either side between the ventral median fissure and the ventral roots of the spinal nerves." [http://medical-dictionary.thefreedictionary.com/ventral+funiculus] +synonym: "anterior funiculus" RELATED [] +xref: UBERON:0002180 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004536 +name: anterior thalamic nucleus +def: "Nucleus situated in the thalamus that is associated with the limbic system and is implicated in learning and episodic memory." [http://en.wikipedia.org/wiki/Anterior_nuclei_of_thalamus] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004537 +name: anterodorsal tegmental nucleus +def: "Nucleus located anterodorsally in the midbrain tegmentum." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004538 +name: anteroventral tegmental nucleus +def: "Nucleus located anteroventrally in the midbrain tegmentum." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004539 +name: basal forebrain +def: "A group of structures that lie in the ventralmost parts of the forebrain and are formed by the derivatives of the subpallium." [XAO:KAB] +synonym: "ventral telencephalon" RELATED [] +xref: UBERON:0002743 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004258 ! subpallium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004540 +name: basal ganglion +def: "Composite structure derived principally from the subpallium and containing numerous ganglia of the ventral telencephalon." [XAO:KAB] +synonym: "basal ganglia" RELATED PLURAL [] +synonym: "basal ganglia nuclei" RELATED [] +synonym: "basal nuclei" RELATED [] +xref: UBERON:0010011 +is_a: XAO:0003160 ! anatomical cluster +relationship: develops_from XAO:0004258 ! subpallium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004539 ! basal forebrain +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004541 +name: bed nucleus of the stria terminalis +def: "A brain structure in the forebrain wrapped around the stria terminalis. Its largest extent can be found around the crossing of the anterior commissure." [UBERON:0001880] +synonym: "bed nucleus striae terminalis" EXACT [] +synonym: "BST" EXACT [] +xref: UBERON:0001880 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004539 ! basal forebrain +relationship: start_stage XAO:1000061 ! NF stage 49 + +[Term] +id: XAO:0004542 +name: central amygdala +def: "A nucleus comprising the central aspect of the amygdala, identified as a target for ascending auditory information from the central thalamic nucleus and as a major afferent to the vocal pattern generator of the hindbrain." [PMID:24005304] +synonym: "CeA" EXACT [] +xref: UBERON:0002883 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004531 ! amygdala +relationship: part_of XAO:0004587 ! striatum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004543 +name: central canal +def: "Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord." [UBERON:0002291] +xref: UBERON:0002291 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004544 +name: central nucleus of the thalamus +def: "Nucleus that is located centrally in the thalamus." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004545 +name: dorsal column nucleus +def: "A nucleus that is situated in the brainstem." [http://en.wikipedia.org/wiki/Dorsal_column_nuclei] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004546 +name: dorsal habenular nucleus +def: "Cell mass in the caudal and dorsal aspect of the dorsal thalamus adjoining the pineal gland." [XAO:KAB] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004556 ! habenula +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0004547 +name: dorsal pallidum +def: "The predominant portion of the globus pallidus in the striatopallidal system, which is defined by connectivity and neurochemical staining. It is distinguished from the ventral pallidum by a boundary that is partially defined by the anterior commissure." [UBERON:0006516] +xref: UBERON:0006516 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004578 ! pallidum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004548 +name: dorsal pallium +def: "Subdivision of thepallium that is located dorsally." [UBERON:0014740] +synonym: "isocortex" RELATED [] +xref: UBERON:0014740 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004302 ! pallium +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004549 +name: dorsal septum +def: "A set of septal nuclei comprising the dorsal aspect of the forebrain septum." [XAO:KAB] +synonym: "Sd" EXACT [] +synonym: "septum dorsalis" EXACT [] +is_a: XAO:0005422 ! septum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004585 ! telencephalon septum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004551 +name: external plexiform layer of the olfactory bulb +def: "Cytoarchitectural part of the olfactory bulb, lying superior to the mitral cell layer and inferior to the glomerular layer. The EPL is mostly neuropil composed almost entirely of mitral and tulfted cell dendrites and granule cell dendrites and their synaptic inputs." [UBERON:0005376] +xref: UBERON:0005376 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004180 ! olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004552 +name: glomerular layer of the olfactory bulb +def: "Superficial layer of the olfactory bulb, composed of spherical glomeruli, where input from olfactory receptor neurons is first organized and processed." [PMID:16765614] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004180 ! olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004553 +name: granule cell +def: "Type of neuron characterized by having very small cell bodies. These cells are found within the granular layers of the cerebellum and the olfactory bulb." [http://en.wikipedia.org/wiki/Granule_cell] +xref: CL:0000120 +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004554 ! granule cell layer of the cerebellum +relationship: part_of XAO:0004555 ! granule cell layer of the olfactory bulb +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004554 +name: granule cell layer of the cerebellum +def: "The innermost layer of the cerebellar cortex, containing densely packed small neurons, mostly granule cells." [UBERON:0002956] +xref: UBERON:0002956 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003098 ! cerebellum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004555 +name: granule cell layer of the olfactory bulb +def: "A layer of the olfactory bulb interior to the mitral cell layer, consisting of inhibitory interneurons." [XAO:KAB] +synonym: "internal granular layer" RELATED [] +xref: UBERON:0005378 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004180 ! olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004556 +name: habenula +def: "Region of the thalamus adjoining the pineal gland." [XAO:KAB] +synonym: "Hb" EXACT [] +xref: UBERON:0001904 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004390 ! dorsal thalamus +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0004557 +name: isthmic nucleus +def: "Nucleus that is a prominant part of the visual system, receiving input from the ipsilateral tectum and sending output to both tecta." [PMID:3497362] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000016 ! midbrain-hindbrain boundary +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004558 +name: lateral amygdala +def: "A nucleus comprising the lateral aspect of the amygdala, implicated in fear conditioning." [http://en.wikipedia.org/wiki/Amygdala] +synonym: "LA" EXACT [] +xref: UBERON:0002886 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004531 ! amygdala +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004559 +name: lateral forebrain bundle +def: "A fiber system that is formed by pallial and subpallial components that join in the caudal telencephalon. It proceeds caudally, piercing the optic tract, to the ventral part of the hypothalamus." [ISBN:3540560130] +synonym: "LFB" EXACT [] +xref: UBERON:2007012 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000011 ! forebrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004560 +name: lateral funiculus +def: "Region of spinal cord white matter that is both ventral to the dorsal root and dorsal to the ventral root." [XAO:KAB] +xref: UBERON:0002179 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004562 +name: lateral hypothalamic nucleus +def: "Diencephalic nucleus that is the lateral part of the ventral hypothalamic zone." [XAO:EJS, ZFA:0000227] +xref: UBERON:0001937 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004070 ! hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004563 +name: lateral pallium +def: "Subdivision of the pallium that is located laterally." [UBERON:0014741] +synonym: "olfactory cortex" RELATED [] +xref: UBERON:0014741 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004302 ! pallium +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004564 +name: lateral septum +def: "A set of septal nuclei comprising the lateral aspect of the forebrain septum." [XAO:KAB] +synonym: "septum lateralis" EXACT [] +synonym: "Sl" EXACT [] +is_a: XAO:0005422 ! septum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004585 ! telencephalon septum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004565 +name: laterodorsal tegmental nucleus +def: "A nucleus situated in the brainstem, spanning the midbrain tegmentum and the pontine tegmentum." [UBERON:0002267] +xref: UBERON:0002267 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004566 +name: locus coeruleus +def: "Nucleus within the brainstem that is the principal site for brain synthesis of norepinephrine." [XAO:KAB] +synonym: "locus caeruleus" EXACT [] +synonym: "locus ceruleus" EXACT [] +xref: UBERON:0002148 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004567 +name: magnocellular preoptic nucleus +def: "A nucleus situated in the preoptic area that contains large neurosecretory neurons." [ISBN:0080877982, ISBN:3540560130] +xref: UBERON:2000248 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004583 ! preoptic area +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0004568 +name: medial amygdala +def: "A nucleus comprising the medial aspect of the amygdala, involved in receiving olfactory information." [http://en.wikipedia.org/wiki/Amygdala] +synonym: "MeA" EXACT [] +xref: UBERON:0002892 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004531 ! amygdala +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004570 +name: medial pallium +def: "Subdivision of the pallium that is located in the medial position." [UBERON:0014738] +synonym: "hippocampus" RELATED [] +synonym: "MP" EXACT [] +xref: UBERON:0014738 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004302 ! pallium +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004571 +name: medial septum +def: "A set of septal nuclei comprising the medial aspect of the forebrain septum." [XAO:KAB] +synonym: "septum medialis" EXACT [] +synonym: "Sm" EXACT [] +is_a: XAO:0005422 ! septum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004585 ! telencephalon septum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004573 +name: mitral cell +def: "Large glutaminergic nerve cell whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex." [MP:0009954] +xref: CL:1001502 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004574 ! mitral cell layer of the olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004574 +name: mitral cell layer of the olfactory bulb +def: "Layer composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer." [UBERON:0004186] +xref: UBERON:0004186 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004180 ! olfactory bulb +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004575 +name: nucleus accumbens +def: "A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen." [UBERON:0001882] +synonym: "Acc" EXACT [] +synonym: "accumbens nucleus" EXACT [] +synonym: "nucleus accumbens septi" RELATED [] +xref: UBERON:0001882 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004587 ! striatum +relationship: start_stage XAO:1000065 ! NF stage 53 + +[Term] +id: XAO:0004576 +name: nucleus of the diagonal band +def: "A brain structure that is part of the septal nuclear complex and is connected with the hippocampus, hypothalamus, and amygdala." [UBERON:0001879] +synonym: "diagonal band" RELATED [] +synonym: "diagonal band of Broca" RELATED [] +xref: UBERON:0001879 +is_a: XAO:0004609 ! neural nucleus +relationship: develops_from XAO:0004258 ! subpallium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004539 ! basal forebrain +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004578 +name: pallidum +def: "Major component of the basal ganglia that is part of the telencephalon and has close functional ties with the subthalamus." [http://en.wikipedia.org/wiki/Globus_pallidus] +synonym: "globus pallidus" EXACT [] +synonym: "Pa" EXACT [] +synonym: "paleostriatum" RELATED [] +synonym: "pallidal nuclei" RELATED [] +xref: UBERON:0001875 +is_a: XAO:0003160 ! anatomical cluster +relationship: develops_from XAO:0004259 ! medial ganglionic eminence +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004540 ! basal ganglion +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004579 +name: posterior commissure +def: "Diencephalic tract that is located in the vicinity of the dorsal diencephalon and mesencephalon and connects the pretectal nuclei." [XAO:EJS, ZFA:0000320] +xref: UBERON:0000936 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004580 +name: dorsal funiculus +def: "Region of spinal cord white matter that is dorsal and medial to the dorsal root." [XAO:KAB] +synonym: "posterior funiculus" RELATED [] +xref: UBERON:0002258 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004581 +name: posterodorsal tegmental nucleus +def: "Nucleus located posterodorsally in the midbrain tegmentum." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004582 +name: posteroventral tegmental nucleus +def: "Nucleus located posteroventrally in the midbrain tegmentum." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004271 ! midbrain tegmentum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004583 +name: preoptic area +def: "Area of the forebrain anterior to the posterior tuberculum and the hypothalamus and ventral to the ventral thalamus." [UBERON:0001928] +synonym: "anterior preoptic area" RELATED [] +synonym: "PO" EXACT [] +synonym: "preoptic nuclei" RELATED [] +synonym: "preoptic region" RELATED [] +xref: UBERON:0001928 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004230 ! anterior hypothalamus +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0004584 +name: raphe nucleus +def: "A cluster of nuclei found in the brain stem, the main function of which is to release serotonin to the rest of the brain." [http://en.wikipedia.org/wiki/Raphe_nuclei] +xref: UBERON:0004684 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004585 +name: telencephalon septum +def: "Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum and the septal nuclei." [UBERON:0000446] +synonym: "Se" RELATED [] +synonym: "septum" BROAD [] +synonym: "septum of telencephalon" EXACT [] +xref: UBERON:0000446 +is_a: XAO:0005422 ! septum +relationship: develops_from XAO:0004258 ! subpallium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004539 ! basal forebrain +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004586 +name: solitary tract +def: "A compact fiber bundle that extends longitudinally through the posterolateral region of the medulla and is surrounded by the nucleus of the solitary tract, and descends to the upper cervical segments of the spinal cord." [UBERON:0002718] +xref: UBERON:0002718 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: part_of XAO:0005048 ! nucleus of the solitary tract +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004587 +name: striatum +def: "A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati." [UBERON:0002435] +synonym: "neostriatum" RELATED [] +synonym: "Str" EXACT [] +synonym: "striatal nuclei" RELATED [] +synonym: "striate nucleus" RELATED [] +xref: UBERON:0002435 +is_a: XAO:0003160 ! anatomical cluster +relationship: develops_from XAO:0004237 ! lateral ganglionic eminence +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004540 ! basal ganglion +relationship: start_stage XAO:1000065 ! NF stage 53 + +[Term] +id: XAO:0004588 +name: subcommissural organ +def: "A small ependymal gland of the circumventricular system, located in the dorsocaudal region of the third ventricle." [XAO:KAB] +xref: UBERON:0002139 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004303 ! pretectum +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004589 +name: subthalamic nucleus +def: "The lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function." [UBERON:0001906] +xref: UBERON:0001906 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004304 ! prethalamus +relationship: part_of XAO:0004540 ! basal ganglion +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004590 +name: torus semicircularis +def: "Multi-tissue structure that is part of the midbrain and develops from the alar plate. It is located dorsal to the lateral tegmentum where it extends into the medial tectal ventricle and receives ascending sensory octavolateralis input." [XAO:EJS, ZFA:0000599] +xref: UBERON:2000599 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000014 ! midbrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004591 +name: ventral habenular nucleus +def: "Cell mass in the caudal and ventral aspect of the dorsal thalamus adjoining the pineal gland." [XAO:KAB] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004556 ! habenula +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0004592 +name: ventral hypothalamic nucleus +def: "Nucleus that is located ventrally in the hypothalamus." [XAO:EJS] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004070 ! hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004593 +name: ventral pallidum +def: "Part of the globus pallidus consisting of the more medial of the two segments." [UBERON:0002778] +xref: UBERON:0002778 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004578 ! pallidum +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004594 +name: ventral pallium +def: "The pallial region located next to the pallium-subpallium boundary." [UBERON:0014913] +xref: UBERON:0014913 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004302 ! pallium +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004595 +name: ventrolateral thalamic nucleus +def: "Nucleus situated in the thalamus that receives inputs from the basal nuclei and the function of which is to help coordinate and plan movement." [http://en.wikipedia.org/wiki/Ventral_lateral_nucleus] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004596 +name: ventromedial thalamic nucleus +def: "Nucleus situated in the thalamus to which somatosensory input is predominantly directed." [ISBN:3540560130] +xref: UBERON:2000459 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004306 ! thalamus +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004597 +name: neuromere +def: "A metameric segment of the central nervous system." [XAO:EJS, ZFA:0001328] +xref: UBERON:0004731 +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000215 ! central nervous system +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004598 +name: prosomere +def: "A neuromere that is part of the presumptive forebrain." [UBERON:0014775] +xref: UBERON:0014775 +is_a: XAO:0004597 ! neuromere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000011 ! forebrain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004599 +name: prosomere 4 +def: "The 4th segment of the developing forebrain." [XAO:EJS] +is_a: XAO:0004598 ! prosomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004600 +name: prosomere 5 +def: "The 5th segment of the developing forebrain." [XAO:EJS] +is_a: XAO:0004598 ! prosomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004601 +name: prosomere 6 +def: "The 6th segment of the developing forebrain." [XAO:EJS] +is_a: XAO:0004598 ! prosomere +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004602 +name: brain ventricle +def: "One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that are lined with an epithelial ependyma, and that contain cerebral-spinal fluid. The system comprises four ventricles, the right and left lateral ventricles (one for each hemisphere), third ventricle, and fourth ventricle." [http://en.wikipedia.org/wiki/Ventricular_system, UBERON:0004086] +synonym: "ventricle" BROAD [] +xref: UBERON:0004086 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004605 +name: mammilary region +def: "A protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei." [UBERON:0002206] +synonym: "corpus mamillare" EXACT [] +synonym: "MA" EXACT [] +synonym: "mammillar area" RELATED [] +xref: UBERON:0002206 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004236 ! posterior hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004606 +name: tuberal region +def: "Structure that lies rostral to the area of the tegmentum and that is a site of dopamine-containing cells." [ISBN:0471733830] +synonym: "caudal tuberculum" RELATED [] +synonym: "posterior tuberculum" RELATED [] +synonym: "Tub" EXACT [] +xref: UBERON:2000633 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004236 ! posterior hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0004607 +name: lateral ventricle +def: "Either of the two brain ventricles that are bilateral (left and right, one for each hemisphere)." [XAO:EJS] +is_a: XAO:0004602 ! brain ventricle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004608 +name: third ventricle +def: "Brain ventricle formed by a median cleft in the diencephalon between the two thalami." [http://en.wikipedia.org/wiki/Third_ventricle] +synonym: "3rd ventricle" EXACT [] +xref: UBERON:0002286 +is_a: XAO:0004602 ! brain ventricle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000013 ! diencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004609 +name: neural nucleus +def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections." [UBERON:0000125] +synonym: "nucleus" BROAD [] +xref: UBERON:0000125 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000215 ! central nervous system +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004610 +name: left ventricle +def: "The lateral ventricle that is located in the left hemisphere of the brain." [XAO:EJS] +is_a: XAO:0004607 ! lateral ventricle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004611 +name: right ventricle +def: "The lateral ventricle that is located in the right hemisphere of the brain." [XAO:EJS] +is_a: XAO:0004607 ! lateral ventricle +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0004612 +name: secretory epithelial cell +def: "Type of epithelial cell that secretes a macromolecule or ion product. In many epithelia, occasional specialized secretory cells are scattered among other, non-secretory cells." [ISBN:0323036635] +synonym: "scattered secretory epithelial cell" RELATED [] +is_a: XAO:0003249 ! epithelial cell +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0004613 +name: non-cililated epidermal cell +def: "Epidermal cell that lacks cilia." [XAO:EJS] +synonym: "non-ciliated epidermal cells" RELATED PLURAL [] +is_a: XAO:0004621 ! epidermal cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0004614 +name: ciliary axoneme +def: "The bundle of microtubules and associated proteins that forms the core of cilia and is responsible for their movements." [GO:0005930] +synonym: "axoneme" EXACT [] +xref: GO:0005930 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005008 ! cilium +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0004615 +name: basal body +def: "A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a cilium that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth." [GO:0005932] +synonym: "ciliary basal body" RELATED [] +xref: GO:0005932 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:0004616 +name: ventrolateral neural tube +def: "The ventrolateral regions of the neural tube, above to the floor plate region and encompassing structurally distinct interneurons (in lateral positions) and the more ventral motor neurons." [XAO:CJZ] +synonym: "ventricular zone" BROAD [] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0004617 +name: dorsolateral neural tube +def: "The dorsolateral regions of the neural tube, ventral to the roof plate region and encompassing structurally distinct sensory neurons (more dorsally) and interneurons (in lateral positions)." [XAO:CJZ] +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0004618 +name: rostral presomitic mesoderm +def: "The region of presomitic mesoderm that lays immediately adjacent and posterior to the last formed somite." [XAO:CJZ] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000057 ! presomitic mesoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0004619 +name: caudal presomitic mesoderm +def: "The most posterior region of presomitic mesoderm where somitomeres have yet to be fated." [XAO:CJZ] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000057 ! presomitic mesoderm +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0004620 +name: neurogenic placode +def: "Cranial placode with neurogenic potential." [UBERON:0009955] +xref: UBERON:0009955 +is_a: XAO:0000305 ! cranial placode +relationship: develops_from XAO:0004092 ! preplacodal ectoderm +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0004621 +name: epidermal cell +def: "An epithelial cell that is part of the epidermis." [XAO:EJS] +xref: CL:1000396 +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0004622 +name: myotome of tail somite 18 +def: "Compartment of tail somite 18 that is a precursor of muscle." [XAO:EJS] +synonym: "myotome of trunk somite 18" EXACT [] +is_a: XAO:0000315 ! myotome +relationship: develops_from XAO:0004528 ! tail somite 18 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0004623 +name: sclerotome of tail somite 18 +def: "Compartment of tail somite 18 that is a precursor of the axial skeleton." [XAO:EJS] +synonym: "sclerotome of somite 18" EXACT [] +synonym: "sclerotome of trunk somite 18" EXACT [] +is_a: XAO:0000397 ! sclerotome +relationship: develops_from XAO:0004528 ! tail somite 18 +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:0004624 +name: fin vasculature +def: "Blood vessel that is part of the fin." [XAO:EJS] +is_a: XAO:0001011 ! blood vessel +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000002 ! fin +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004625 +name: dorsal fin vasculature +def: "Blood vessel that is part of the dorsal fin." [XAO:EJS] +is_a: XAO:0001011 ! blood vessel +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004063 ! dorsal fin +relationship: part_of XAO:0004624 ! fin vasculature +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004626 +name: ventral fin vasculature +def: "Blood vessel that is part of the ventral fin." [XAO:EJS] +is_a: XAO:0001011 ! blood vessel +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004624 ! fin vasculature +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004627 +name: ventral blood island border +def: "Blood vessel that is part of the ventral blood island." [XAO:EJS] +synonym: "vbib" EXACT [] +is_a: XAO:0001011 ! blood vessel +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000049 ! NF stage 35 and 36 +relationship: part_of XAO:0000067 ! ventral blood island +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0004628 +name: posterior ventral blood island +def: "The erythroid-forming compartment of the ventral blood island." [PMID:18594023] +synonym: "pvbi" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0004473 ! ventral mesoderm +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000067 ! ventral blood island +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0005000 +name: matrix-based tissue +def: "A tissue whose predominant feature is extracellular matrix that may or may not be highly hydrated or calcified." [UBERON:0007475] +xref: UBERON:0007475 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2015-04-15T18:09:42Z + +[Term] +id: XAO:0005001 +name: acellular bone tissue +def: "Mineralized bone tissue that has terminally differentiated osteoblasts but lacks osteocytes." [UBERON:4000122] +xref: UBERON:4000122 +is_a: XAO:0004040 ! mineralized bone tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2015-04-20T17:49:35Z + +[Term] +id: XAO:0005002 +name: multicellular anatomical structure +def: "An anatomical structure that has more than one cell as a part." [CARO:0010000] +synonym: "multicellular structure" EXACT [] +xref: CARO:0010000 +xref: UBERON:0010000 +is_a: XAO:0003000 ! anatomical structure +relationship: develops_from XAO:0000113 ! embryo +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003004 ! whole organism +relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) +created_by: eriksegerdell +creation_date: 2015-05-12T17:50:30Z + +[Term] +id: XAO:0005003 +name: larval intestinal epithelium +def: "Epithelium that covers the small and large intestine in the larval frog." [http://en.wikipedia.org/wiki/Intestinal_epithelium, XAO:EJS] +synonym: "larval gut epithelium" EXACT [] +is_a: XAO:0003200 ! gut epithelium +is_a: XAO:0004008 ! simple columnar epithelium +relationship: end_stage XAO:1000010 ! juvenile frog stage +relationship: part_of XAO:0000129 ! intestine +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2015-05-14T17:36:26Z + +[Term] +id: XAO:0005004 +name: adult intestinal epithelium +def: "Epithelium that covers the small and large intestine in the adult frog." [http://en.wikipedia.org/wiki/Intestinal_epithelium, XAO:EJS] +synonym: "adult gut epithelium" EXACT [] +is_a: XAO:0003200 ! gut epithelium +is_a: XAO:0004008 ! simple columnar epithelium +relationship: develops_from XAO:0005236 ! intestinal stem cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000129 ! intestine +relationship: start_stage XAO:1000093 ! adult frog stage +created_by: eriksegerdell +creation_date: 2015-05-14T17:38:16Z + +[Term] +id: XAO:0005005 +name: left +def: "Spatial concept pertaining to being located on or directed toward the side of the body to the west when facing north." [NCIt:Left] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction +created_by: eriksegerdell +creation_date: 2015-05-14T17:39:42Z + +[Term] +id: XAO:0005006 +name: right +def: "Spatial concept pertaining to being located on or directed toward the side of the body to the east when facing north." [NCIt:Right] +subset: anatomical_site_slim +is_a: XAO:0003185 ! anatomical direction +created_by: eriksegerdell +creation_date: 2015-05-14T17:41:09Z + +[Term] +id: XAO:0005007 +name: Muller cell +def: "Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus usually in the middle of the inner nuclear layer." [CL:0011107] +synonym: "Muller glia" RELATED PLURAL [] +xref: CL:0011107 +is_a: XAO:0004308 ! glial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000009 ! retina +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2015-05-14T17:43:09Z + +[Term] +id: XAO:0005008 +name: cilium +def: "Specialized protrusion of a cell composed of microtubules and serving a role in intercellular signaling." [XAO:KAB] +synonym: "cilia" RELATED PLURAL [] +xref: GO:0005929 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005017 ! ciliated cell +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:45:51Z + +[Term] +id: XAO:0005009 +name: mitotic spindle +def: "Array of microtubules and associated molecules that forms between opposite poles of a cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." [GO:0005819] +synonym: "spindle" EXACT [] +xref: GO:0005819 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:48:54Z + +[Term] +id: XAO:0005010 +name: growth cone +def: "Migrating motile tip of a growing nerve cell axon or dendrite." [GO:0030426] +xref: GO:0030426 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003023 ! neuron +relationship: part_of XAO:0005317 ! neuron projection +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2015-05-14T17:50:17Z + +[Term] +id: XAO:0005011 +name: centriole +def: "A cellular organelle, found close to the nucleus in many cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle." [GO:0005814] +xref: GO:0005814 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005014 ! centrosome +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:51:38Z + +[Term] +id: XAO:0005012 +name: kinetochore +def: "A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules." [GO:0000776] +xref: GO:0000776 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:53:24Z + +[Term] +id: XAO:0005013 +name: centromere +def: "The region of a chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid." [ISBN:0198506732] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:55:01Z + +[Term] +id: XAO:0005014 +name: centrosome +def: "A structure comprising a core structure and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many cells, though it changes continually during the cell-division cycle." [GO:0005813] +xref: GO:0005813 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T17:56:06Z + +[Term] +id: XAO:0005015 +name: axon +def: "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." [GO:0030424] +xref: GO:0030424 +is_a: XAO:0005317 ! neuron projection +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003023 ! neuron +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2015-05-14T19:09:57Z + +[Term] +id: XAO:0005016 +name: dendrite +def: "A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." [GO:0030425] +xref: GO:0030425 +is_a: XAO:0005317 ! neuron projection +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003023 ! neuron +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2015-05-14T19:12:27Z + +[Term] +id: XAO:0005017 +name: ciliated cell +def: "A cell that has a filiform extrusion of the cell surface." [CL:0000064] +xref: CL:0000064 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2015-05-14T19:18:22Z + +[Term] +id: XAO:0005018 +name: spinal neuron +def: "A neuron of the spinal cord." [XAO:EJS] +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-16T14:08:54Z + +[Term] +id: XAO:0005019 +name: paired dorsal aorta +def: "The embryonic right and left aortas that develop in parallel with the heart and gain access to it via the aortic arches. Later the paired dorsal aortic anlagen unite and finally form the unpaired descending aorta of the adult." [http://www.embryology.ch/anglais/pcardio/arterien02.html] +synonym: "left dorsal aorta" NARROW [] +synonym: "paired dorsal aortae" RELATED PLURAL [] +synonym: "right dorsal aorta" NARROW [] +is_a: XAO:0003010 ! aorta +relationship: develops_from XAO:0000085 ! intermediate mesoderm +relationship: develops_from XAO:0000357 ! arterial endothelium +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: eriksegerdell +creation_date: 2015-05-16T14:25:29Z + +[Term] +id: XAO:0005020 +name: stromal cell +def: "A connective tissue cell of any organ." [http://en.wikipedia.org/wiki/Stromal_cell] +xref: CL:0000499 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0001017 ! connective tissue +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: eriksegerdell +creation_date: 2015-05-16T14:43:13Z + +[Term] +id: XAO:0005021 +name: interstitial cell of Leydig +def: "A cell that is located in the interstitial space between the seminiferous tubules and produces male androgens." [ISBN:9781461348764] +synonym: "interstitial cell" BROAD [] +is_a: XAO:0005020 ! stromal cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000157 ! testis +relationship: start_stage XAO:1000064 ! NF stage 52 +created_by: eriksegerdell +creation_date: 2015-05-16T14:57:42Z + +[Term] +id: XAO:0005022 +name: hepatocyte +def: "A type of cell comprising the main structural component of the liver." [CL:0000182] +xref: CL:0000182 +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000133 ! liver +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 +created_by: eriksegerdell +creation_date: 2015-05-16T15:02:39Z + +[Term] +id: XAO:0005023 +name: granular gland +def: "A surface structure principally responsible for the production of noxious or toxic secretion with an effect on numerous species of vertebrates. The glands are almost uniformly distributed, on both ventral and dorsal skin." [DOI:10.1016/0300-9629(95)98515-I] +synonym: "poison gland" BROAD [] +xref: UBERON:3010602 +is_a: XAO:0005071 ! skin gland +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-16T15:11:53Z + +[Term] +id: XAO:0005024 +name: olfactory epithelium +def: "A sensory epithelium inside the nasal cavity that is responsible for detecting odors." [UBERON:0001997] +xref: UBERON:0001997 +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0004092 ! preplacodal ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003196 ! olfactory system +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-16T15:26:20Z + +[Term] +id: XAO:0005025 +name: macrophage +def: "A mononuclear phagocyte present in a variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." [CL:0000235] +synonym: "histiocyte" EXACT [] +xref: CL:0000235 +is_a: XAO:0003239 ! circulating cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000124 ! blood +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2015-05-16T15:34:19Z + +[Term] +id: XAO:0005026 +name: presumptive rhombomere +def: "Embryonic structure that gives rise to a rhombomere." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000037 ! NF stage 21 +relationship: start_stage XAO:1000032 ! NF stage 11.5 +created_by: eriksegerdell +creation_date: 2015-05-18T17:38:18Z + +[Term] +id: XAO:0005027 +name: forebrain-midbrain boundary +def: "The part of the brain that is the morphological boundary between the forebrain and midbrain." [XAO:EJS] +is_a: XAO:0004003 ! anatomical line +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0000249 ! neural plate +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-18T17:39:40Z + +[Term] +id: XAO:0005028 +name: ventricular layer of the optic tectum +def: "Layer of the optic tectum that contains radial glial and other non-neuronal cells." [PMID:23531884] +synonym: "ventricular layer" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003226 ! optic tectum +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2015-05-18T17:40:54Z + +[Term] +id: XAO:0005029 +name: neuropil of the optic tectum +def: "Layer of the optic tectum that mainly consists of ascending sensory axons and tectal dendrites." [PMID:23531884] +synonym: "neuropil" BROAD [] +xref: UBERON:0002606 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003226 ! optic tectum +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2015-05-18T17:42:02Z + +[Term] +id: XAO:0005030 +name: cell body layer of the optic tectum +def: "Layer of the optic tectum that consists of tectal somata." [PMID:23531884] +synonym: "cell body layer" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003226 ! optic tectum +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2015-05-18T17:43:13Z + +[Term] +id: XAO:0005031 +name: radial glial cell +def: "A cell present in the developing central nervous system. It functions as both a precursor cell and as a scaffold to support neuronal migration. Some have a multipotent ability, as they can differentiate into neurons and radial glial cells by asymmetric divisions during the period of embryonic neurogenesis. They occur mainly in the ventricular layer of the tectum and decrease in number as the brain matures." [CL:0000681, XAO:curators] +synonym: "radial glia" RELATED PLURAL [] +synonym: "RG" EXACT [] +xref: CL:0000681 +is_a: XAO:0004308 ! glial cell +relationship: develops_from XAO:0005032 ! neural stem cell +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000177 ! nervous system +relationship: part_of XAO:0005028 ! ventricular layer of the optic tectum +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-18T17:46:16Z + +[Term] +id: XAO:0005032 +name: neural stem cell +def: "A cell that, in the early stages of the brain, are generated from the ectoderm-derived neural epithelium and commit to differentiate into either neurons or radial glial cells. It is well known that radial glial cells have distinctive morphological characteristics and can act as neural progenitor cells (NPCs) or neural stem cells (NSCs), in addition to guiding the migration of differentiating neurons in the central nervous system." [XAO:curators] +synonym: "neural stem cells" RELATED PLURAL [] +synonym: "neuronal stem cell" EXACT [] +synonym: "NSC" EXACT [] +xref: CL:0000047 +is_a: XAO:0003054 ! stem cell +relationship: develops_from XAO:0000042 ! neuroectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2015-05-18T17:55:47Z + +[Term] +id: XAO:0005033 +name: progenitor cell +def: "A cell that, like a stem cell, has a tendency to differentiate into a specific type of cell, but is already more specific than a stem cell and is pushed to differentiate into its target cell." [http://en.wikipedia.org/wiki/Progenitor_cell] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2015-05-18T18:02:10Z + +[Term] +id: XAO:0005034 +name: neural progenitor cell +def: "A progenitor cell of the nervous system." [XAO:EJS] +synonym: "neuronal progenitor cell" EXACT [] +synonym: "NPC" EXACT [] +is_a: XAO:0005033 ! progenitor cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000177 ! nervous system +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2015-05-18T18:03:47Z + +[Term] +id: XAO:0005035 +name: Mauthner cell +def: "Any of a pair of large, easily identifiable, reticulospinal neurons at the level of the ear in the hindbrain. Importantly, they enable the escape reflex. Inner ear vestibular and auditory neurons form synapses on the lateral dendrite of the ipsilateral Mauthner cell, which in turn form synapses on contralateral spinal motor neurons to activate the C-start escape response." [XAO:curators] +synonym: "Mauthner neuron" EXACT [] +xref: CL:0000246 +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000015 ! hindbrain +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-18T18:07:10Z + +[Term] +id: XAO:0005036 +name: Eberth-Kastschenko layer +def: "A calcified dermal layer that is found between the stratum spongiosum and the stratum compactum of the skin." [PMID:23480373] +synonym: "calcified dermal layer" BROAD [] +synonym: "EK layer" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000217 ! dermis +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-18T18:11:23Z + +[Term] +id: XAO:0005037 +name: migrating macrophage +def: "Any of the hematopoietic stem cell derived phagocytic cells that are first observed in the ventral blood island at NF stages 17-18 and at stage 20 begin to migrate over the whole embryo between the epidermis and the mesoderm, completing their migration by stage 25." [PMID:12204257, PMID:15305302, PMID:18684398] +synonym: "embryonic macrophage" EXACT [] +is_a: XAO:0005025 ! macrophage +relationship: develops_from XAO:0003055 ! hematopoietic stem cell +relationship: develops_from XAO:0004473 ! ventral mesoderm +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0000028 ! epidermis +relationship: part_of XAO:0000050 ! mesoderm +relationship: part_of XAO:0000067 ! ventral blood island +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2015-05-18T18:14:55Z + +[Term] +id: XAO:0005038 +name: nucleus +def: "A membrane-bounded organelle of in which chromosomes are housed and replicated. In most cells, it contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some specialized cell types, RNA metabolism or DNA replication may be absent." [GO:0005634] +synonym: "cell nucleus" EXACT [] +xref: GO:0005634 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2015-05-18T18:18:55Z + +[Term] +id: XAO:0005039 +name: cytoplasm +def: "All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GO:0005737] +xref: GO:0005737 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2015-05-18T18:25:53Z + +[Term] +id: XAO:0005040 +name: anterior semicircular canal +def: "The anterior (superior) of the two vertically oriented semicircular canals, which are situated at right angles to each other." [http://en.wikipedia.org/wiki/Semicircular_canal] +synonym: "superior semicircular canal" EXACT [] +xref: UBERON:0001841 +is_a: XAO:0000198 ! semicircular canal +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2015-05-19T21:03:02Z + +[Term] +id: XAO:0005041 +name: lateral semicircular canal +def: "The laterally, or horizontally, oriented of the three semicircular canals." [http://en.wikipedia.org/wiki/Semicircular_canal] +synonym: "horizontal semicircular canal" EXACT [] +xref: UBERON:0001843 +is_a: XAO:0000198 ! semicircular canal +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2015-05-19T21:03:23Z + +[Term] +id: XAO:0005042 +name: posterior semicircular canal +def: "The posterior of the two vertically oriented semicircular canals, which are situated at right angles to each other." [http://en.wikipedia.org/wiki/Semicircular_canal] +synonym: "inferior semicircular canal" EXACT [] +xref: UBERON:0001842 +is_a: XAO:0000198 ! semicircular canal +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2015-05-19T21:03:33Z + +[Term] +id: XAO:0005043 +name: skeletal muscle satellite cell +def: "An elongated, spindle-shaped cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers." [CL:0000594] +synonym: "satellite cell" BROAD [] +xref: CL:0000594 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000174 ! skeletal muscle +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2015-05-19T21:14:01Z + +[Term] +id: XAO:0005044 +name: Schwann cell +def: "A glial cell that ensheaths axons of neurons in the peripheral nervous system and is necessary for their maintainance and function. Multiple Schwann cells wrap each axon." [CL:0002573, XAO:curators] +synonym: "neurilemmal cell" EXACT [] +xref: CL:0002573 +is_a: XAO:0004308 ! glial cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: part_of XAO:0003047 ! nerve +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2015-05-19T21:17:00Z + +[Term] +id: XAO:0005045 +name: dorsal crest of the endoderm +def: "Dorsal endoderm that is adjacent to the notochord." [PMID:14745962] +synonym: "dorsal crest" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2015-05-19T21:19:33Z + +[Term] +id: XAO:0005046 +name: caudal tuberal region +def: "The caudal zone of the tuberal region of the hypothalamus." [XAO:EJS] +synonym: "CT" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004606 ! tuberal region +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2015-05-20T18:39:56Z + +[Term] +id: XAO:0005047 +name: rostral tuberal region +def: "The rostral zone of the tuberal region of the hypothalamus." [XAO:EJS] +synonym: "RT" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004606 ! tuberal region +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2015-05-20T18:40:59Z + +[Term] +id: XAO:0005048 +name: nucleus of the solitary tract +def: "A series of nuclei forming a column of grey matter embedded in the medulla, through the center of which runs the solitary tract. The solitary tract and nucleus are structures that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX) and vagus (X) cranial nerves." [http://en.wikipedia.org/wiki/Solitary_nucleus] +synonym: "Nsol" EXACT [] +synonym: "nucleus of solitary tract" EXACT [] +synonym: "solitary nucleus" EXACT [] +xref: UBERON:0009050 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T18:42:06Z + +[Term] +id: XAO:0005049 +name: prethalamus basal plate +def: "The ventral half of the developing neural tube that is the prethalamus." [XAO:EJS] +synonym: "basal plate of prosomere 3" EXACT [] +synonym: "p3b" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004304 ! prethalamus +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T18:45:52Z + +[Term] +id: XAO:0005050 +name: parabrachial area +def: "Cell area that receives signals from the solitary nucleus and transmits signals to the medulla oblongata, spinal cord, amygdala, and hypothalamus." [http://en.wikipedia.org/wiki/Parabrachial_area, ISBN:9783642621277] +synonym: "parabrachial nucleus" EXACT [] +synonym: "PB" EXACT [] +xref: UBERON:0007634 +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:01:25Z + +[Term] +id: XAO:0005051 +name: retromammillary area +def: "Hypothalamic region that with the mammillary nuclei forms the mammillary complex." [PMID:18597750] +synonym: "RM" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004070 ! hypothalamus +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:04:47Z + +[Term] +id: XAO:0005052 +name: nucleus reticularis medialis +def: "Medial nucleus of the reticular nucleus of the brain stem." [ISBN:9783642621277] +synonym: "Rm" EXACT [] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:07:47Z + +[Term] +id: XAO:0005053 +name: nucleus reticularis superior +def: "Superior nucleus of the reticular nucleus of the brain stem." [ISBN:9783642621277] +synonym: "Rs" EXACT [] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:07:51Z + +[Term] +id: XAO:0005054 +name: nucleus reticularis inferior +def: "Inferior nucleus of the reticular nucleus of the brain stem." [ISBN:9783642621277] +synonym: "Ri" EXACT [] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003100 ! medulla oblongata +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:07:57Z + +[Term] +id: XAO:0005055 +name: ventral septum +def: "A set of septal nuclei comprising the ventral aspect of the forebrain septum." [XAO:EJS] +synonym: "septum ventralis" EXACT [] +synonym: "Sv" EXACT [] +is_a: XAO:0005422 ! septum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004585 ! telencephalon septum +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2015-05-20T19:13:25Z + +[Term] +id: XAO:0005056 +name: supraoptoparaventricular region +def: "The dorsal region of the alar hypothalamus." [PMID:24122702] +synonym: "SPV" EXACT [] +is_a: XAO:0004609 ! neural nucleus +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004230 ! anterior hypothalamus +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2015-05-20T19:17:57Z + +[Term] +id: XAO:0005057 +name: stria terminalis +def: "A structure in the brain consisting of a band of fibers running along the lateral margin of the ventricular surface of the thalamus. Serving as a major output pathway of the amygdala, it runs from its centromedial division to the ventral medial nucleus of the hypothalamus." [http://en.wikipedia.org/wiki/Stria_terminalis] +synonym: "st" EXACT [] +xref: UBERON:0003029 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-20T19:19:50Z + +[Term] +id: XAO:0005058 +name: stratum spongiosum +def: "Dermal layer containing loose connective tissue and several types of glands." [PMID:7723046] +xref: UBERON:3010599 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000217 ! dermis +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-21T21:38:10Z + +[Term] +id: XAO:0005059 +name: stratum compactum +def: "Dermal layer composed of alternating sheets of parallel fibers." [PMID:7723046] +xref: UBERON:0007377 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000217 ! dermis +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-21T21:39:20Z + +[Term] +id: XAO:0005060 +name: glomerular mesangial cell +def: "A type of smooth muscle-like pericyte that abuts and surrounds the filtration capillaries within the glomerulus." [PMID:9674692] +synonym: "mesangial cell" BROAD [] +synonym: "mesangial-like cell" BROAD [] +xref: CL:1000742 +is_a: XAO:0003264 ! pericyte +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0000318 ! glomus +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2015-05-21T21:40:28Z + +[Term] +id: XAO:0005061 +name: glomerular epithelial cell +def: "An epithelial cell that is part of the glomus." [XAO:EJS] +is_a: XAO:0003249 ! epithelial cell +relationship: end_stage XAO:1000067 ! NF stage 55 +relationship: part_of XAO:0000318 ! glomus +relationship: start_stage XAO:1000045 ! NF stage 29 and 30 +created_by: eriksegerdell +creation_date: 2015-05-21T21:42:24Z + +[Term] +id: XAO:0005062 +name: proepicardium +def: "An embryonic progenitor cell type that comprises a population that provides the epicardium, the majority of the cardiac interstitium, the coronary vasculature, and possibly some cardiomyocytes." [XAO:curators] +synonym: "PE" EXACT [] +is_a: XAO:0005033 ! progenitor cell +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2015-05-21T21:43:43Z + +[Term] +id: XAO:0005063 +name: external coil of the small intestine +def: "Part of the double coil of the small intestine, consisting of anti-clockwise loops of intestine proximal to the internal coil." [PMID:10603354] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000130 ! small intestine +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2015-05-21T21:46:18Z + +[Term] +id: XAO:0005064 +name: internal coil of the small intestine +def: "Part of the double coil of the small intestine, consisting of clockwise loops of intestine distal to the external coil." [PMID:10603354] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000130 ! small intestine +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2015-05-21T21:47:31Z + +[Term] +id: XAO:0005065 +name: sciatic nerve +def: "Nerve that provides the connection to the nervous system for nearly the whole of the skin of the leg, the muscles of the back of the thigh, and those of the leg and foot." [http://en.wikipedia.org/wiki/Sciatic_nerve] +synonym: "ischiadic nerve" EXACT [] +xref: UBERON:0001322 +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2015-05-24T12:22:58Z + +[Term] +id: XAO:0005066 +name: optic disc +def: "The location where ganglion cell axons exit the eye to form the optic nerve." [UBERON:0001783] +synonym: "optic nerve head" EXACT [] +xref: UBERON:0001783 +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000179 ! eye +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2015-05-24T12:24:26Z + +[Term] +id: XAO:0005067 +name: typhlosole +def: "A longitudinal fold of the wall projecting into the cavity of the intestine." [http://www.merriam-webster.com/dictionary/typhlosole] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000129 ! intestine +relationship: start_stage XAO:1000053 ! NF stage 41 +created_by: eriksegerdell +creation_date: 2015-05-24T12:26:06Z + +[Term] +id: XAO:0005068 +name: motor axon +def: "An axon that is part of a motor neuron and which projects outside the spinal cord to directly or indirectly control muscles." [http://en.wikipedia.org/wiki/Motor_neuron] +synonym: "motor axons" RELATED PLURAL [] +is_a: XAO:0005015 ! axon +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004217 ! motor neuron +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2015-05-24T12:26:56Z + +[Term] +id: XAO:0005069 +name: iliofibularis +def: "A hindlimb muscle that is used in locomotion and which contains a population of slow or tonic fibers, as well as twitch fibers." [PMID:434137] +is_a: XAO:0000172 ! muscle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003031 ! hindlimb +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2015-05-24T12:28:16Z + +[Term] +id: XAO:0005070 +name: sulcus limitans of neural tube +def: "A shallow, longitudinal groove separating the developing gray matter into a basal and alar plates along the length of the neural tube." [http://en.wikipedia.org/wiki/Sulcus_limitans_(neural_tube)] +synonym: "sulcus limitans" BROAD [] +xref: UBERON:0005478 +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000034 ! NF stage 18 +created_by: eriksegerdell +creation_date: 2015-05-24T12:29:59Z + +[Term] +id: XAO:0005071 +name: skin gland +def: "A gland that is part of the skin." [UBERON:0002419] +xref: UBERON:0002419 +is_a: XAO:0003028 ! surface structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000023 ! skin +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-24T12:36:00Z + +[Term] +id: XAO:0005072 +name: skin mucous gland +def: "A mucous gland that is part of the skin." [UBERON:0004790] +synonym: "mucous gland" BROAD [] +xref: UBERON:0004790 +is_a: XAO:0005071 ! skin gland +is_a: XAO:0005073 ! mucous gland +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-24T12:39:09Z + +[Term] +id: XAO:0005073 +name: mucous gland +def: "A gland in which the principal secretory cells are mucus secreting cells." [UBERON:0000414] +synonym: "mucus gland" EXACT [] +xref: UBERON:0000414 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-24T12:44:20Z + +[Term] +id: XAO:0005074 +name: skin seromucous gland +def: "A gland of the skin in which some secretory cells are serous and some mucous." [http://www.medilexicon.com/medicaldictionary.php?t=37219] +synonym: "seromucous gland" BROAD [] +is_a: XAO:0005071 ! skin gland +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-24T12:48:54Z + +[Term] +id: XAO:0005075 +name: Bowman's gland +def: "Any of the branched tubuloalveolar glands situated in the mucous membrane of the olfactory region of the nasal cavity that produce mucus to moisten the olfactory epithelium and dissolve odor-containing gases." [http://medical-dictionary.thefreedictionary.com/olfactory+gland] +synonym: "olfactory gland" EXACT [] +synonym: "olfactory gland of Bowman" EXACT [] +xref: UBERON:0002232 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005024 ! olfactory epithelium +relationship: start_stage XAO:1000039 ! NF stage 23 +created_by: eriksegerdell +creation_date: 2015-05-24T12:53:34Z + +[Term] +id: XAO:0005076 +name: anterior entopeduncular region +def: "A defined region within the ventral telencephalon that gives rise to GABAergic and cholinergic cortical interneurons and is also a source of early-born oligodendrocytes in the telencephalon." [http://discovery.lifemapsc.com/in-vivo-development/neural-tube/anterior-entopeduncular-area] +synonym: "AEP" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000047 ! NF stage 32 +created_by: eriksegerdell +creation_date: 2015-05-24T12:57:36Z + +[Term] +id: XAO:0005077 +name: secondary myofiber +def: "Multinucleate cell formed by later myoblasts that cling by pseudopodia pushed into the surfaces of existing myotubes, and that instead of fusing with the myotube fuse with each other." [ISBN:9780123847317] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000172 ! muscle +relationship: start_stage XAO:1000043 ! NF stage 27 +created_by: eriksegerdell +creation_date: 2015-05-24T13:08:46Z + +[Term] +id: XAO:0005078 +name: dorsomedial edge of myotome +def: "Muscle-forming part of each myotome that splits from the ventrolateral edge and gives rise to the epaxial musculature." [ISBN:9780470654538] +synonym: "dorsomedial edge" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000315 ! myotome +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2015-05-24T13:15:22Z + +[Term] +id: XAO:0005079 +name: ventrolateral edge of myotome +def: "Muscle-forming part of each myotome that splits from the dorsomedial edge and gives rise to the hypaxial musculature." [ISBN:9780470654538] +synonym: "ventrolateral edge" BROAD [] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000315 ! myotome +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2015-05-24T13:21:29Z + +[Term] +id: XAO:0005080 +name: dermomyotome +def: "The bilaminar epithelium formed from the myotome and dermatome." [UBERON:0004290] +synonym: "dermamyotome" EXACT [] +xref: UBERON:0004290 +is_a: XAO:0004006 ! multilaminar epithelium +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000058 ! somite +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2015-05-24T13:29:14Z + +[Term] +id: XAO:0005081 +name: egg jelly +def: "A gelatinous layer that surrounds the oocyte and releases chemoattractants that activate and guide sperm to the oocyte." [http://en.wikipedia.org/wiki/Egg_jelly] +is_a: XAO:0003162 ! acellular anatomical structure +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: start_stage XAO:1000085 ! oocyte stage III +created_by: eriksegerdell +creation_date: 2015-05-24T13:34:37Z + +[Term] +id: XAO:0005082 +name: lampbrush chromosome +def: "A special form of chromosome found in growing oocytes, transforming into the lampbrush form because of an active transcription of many genes, and organized into a series of chromomeres with large chromatin loops extended laterally." [http://en.wikipedia.org/wiki/Lampbrush_chromosome] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000088 ! oocyte stage VI +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2015-05-24T13:38:12Z + +[Term] +id: XAO:0005083 +name: egg cell-free extract +namespace: xenopus_anatomy_in_vitro +def: "A cell-free extract obtained from oocytes." [XAO:EJS] +is_a: XAO:0004291 ! cell-free extract +created_by: eriksegerdell +creation_date: 2015-05-24T13:44:37Z + +[Term] +id: XAO:0005084 +name: blastomere D1 +def: "Blastomere which lies adjacent to the prospective dorsal midline of the animal hemisphere at the eight-cell stage." [PMID:3596014] +synonym: "D1" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0003016 ! blastomere +relationship: end_stage XAO:1000014 ! NF stage 4 (8-cell) +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005085 +name: blastomere D2 +def: "Blastomere which lies adjacent to the prospective dorsal midline of the vegetal hemisphere at the eight-cell stage." [PMID:3596014] +synonym: "D2" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0003016 ! blastomere +relationship: end_stage XAO:1000014 ! NF stage 4 (8-cell) +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005086 +name: blastomere V1 +def: "Blastomere which lies adjacent to the prospective ventral midline of the animal hemisphere at the eight-cell stage." [PMID:3596014] +synonym: "V1" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0003016 ! blastomere +relationship: end_stage XAO:1000014 ! NF stage 4 (8-cell) +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005087 +name: blastomere V2 +def: "Blastomere which lies adjacent to the prospective ventral midline of the vegetal hemisphere at the eight-cell stage." [PMID:3596014] +synonym: "V2" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0003016 ! blastomere +relationship: end_stage XAO:1000014 ! NF stage 4 (8-cell) +relationship: start_stage XAO:1000014 ! NF stage 4 (8-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005088 +name: blastomere D1.1 +def: "Blastomere which lies adjacent to the prospective dorsal midline of the animal hemisphere at the 16-cell stage." [PMID:3596014] +synonym: "D1.1" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005084 ! blastomere D1 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005089 +name: blastomere D1.2 +def: "Blastomere which lies in the animal hemisphere lateral to blastomere D1.1 at the 16-cell stage." [PMID:3596014] +synonym: "D1.2" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005084 ! blastomere D1 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005090 +name: blastomere D2.1 +def: "Blastomere which lies adjacent to the prospective dorsal midline of the vegetal hemisphere at the 16-cell stage." [PMID:3596014] +synonym: "D2.1" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005085 ! blastomere D2 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005091 +name: blastomere D2.2 +def: "Blastomere which lies in the vegetal hemisphere lateral to blastomere D2.1 at the 16-cell stage." [PMID:3596014] +synonym: "D2.2" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005085 ! blastomere D2 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005092 +name: blastomere V1.1 +def: "Blastomere which lies adjacent to the prospective ventral midline of the animal hemisphere at the 16-cell stage." [PMID:3596014] +synonym: "V1.1" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005086 ! blastomere V1 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005093 +name: blastomere V1.2 +def: "Blastomere which lies in the animal hemisphere lateral to V1.1 at the 16-cell stage." [PMID:3596014] +synonym: "V1.2" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005086 ! blastomere V1 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005094 +name: blastomere V2.1 +def: "Blastomere which lies adjacent to the prospective ventral midline of the vegetal hemisphere at the 16-cell stage." [PMID:3596014] +synonym: "V2.1" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005087 ! blastomere V2 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005095 +name: blastomere V2.2 +def: "Blastomere which lies in the vegetal hemisphere lateral to V2.1 at the 16-cell stage." [PMID:3596014] +synonym: "V2.2" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005087 ! blastomere V2 +relationship: end_stage XAO:1000015 ! NF stage 5 (16-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005096 +name: blastomere D1.1.1 +def: "Blastomere which lies adjacent to the prospective dorsal midline in the first tier of blastomeres. It contributes to a variety of tissues and organs, including the cement gland, brain, retina, lens, cranial ganglia, otic vesicle, neural crest, spinal cord, somites, liver, gut and pharynx." [PMID:3596014] +synonym: "A1" RELATED [] +synonym: "D1.1.1" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005088 ! blastomere D1.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005097 +name: blastomere D1.1.2 +def: "Blastomere which lies adjacent to the prospective dorsal midline, posterior to its sister cell, blastomere D1.1.1, in the second tier of blastomeres. It contributes cells to a variety of tissues and organs, including the stomodeum, retina, epidermis, lens, cranial ganglia, epibranchial placodes, neural crest, brain, spinal cord, gut, liver, pharynx, somites, and archenteron roof." [PMID:3596014] +synonym: "B1" RELATED [] +synonym: "D1.1.2" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005088 ! blastomere D1.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005098 +name: blastomere D1.2.1 +def: "Blastomere which lies lateral to blastomere D1.1.1 and is in the first tier of blastomeres. It contributes to a variety of tissues and organs, including the cement gland, head epidermis, olfactory epithelium, lens, cranial ganglia, otic vesicle, epidermis, tail fin, neural crest, retina, hindbrain, spinal cord, pharyngeal arches, caudal notochord and hindgut." [PMID:3596014] +synonym: "A2" RELATED [] +synonym: "D1.2.1" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005089 ! blastomere D1.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005099 +name: blastomere D1.2.2 +def: "Blastomere which lies lateral to blastomere D1.1.2, posterior to its sister cell, blastomere D1.2.1, in the second tier of blastomeres. It contributes to a variety of tissues and organs including fin, epidermis, cement gland, olfactory epithelium, neural crest, lens, cranial ganglia, retina, brain, notochord, somites, pronephric kidney, lateral plate mesoderm, pharynx, foregut, hindgut and archenteron roof." [PMID:3596014] +synonym: "B2" RELATED [] +synonym: "D1.2.2" RELATED [] +is_a: XAO:0005113 ! dorsal animal hemisphere blastomere +relationship: develops_from XAO:0005089 ! blastomere D1.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005100 +name: blastomere D2.1.1 +def: "Blastomere which lies adjacent to the prospective dorsal midline in the fourth tier of blastomeres. It contributes largely to endodermal and mesodermal structures including the branchial and lateral plate mesoderm, foregut, liver, hindgut, some of the trunk, and a small number of cells contributing to neural crest of ectodermal origin." [PMID:3596014] +synonym: "D1" RELATED [] +synonym: "D2.1.1" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005090 ! blastomere D2.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005101 +name: blastomere D2.1.2 +def: "Blastomere which lies adjacent to the prospective dorsal midline, anterior to its sister cell, blastomere D2.1.1, in the third tier of blastomeres. It contributes to mostly endodermal and mesodermal structures including the heart, head mesenchyme, notochord, somites, lateral plate mesoderm, foregut, hindgut, and a few cells of ectodermal origin (in cranial ganglia and neural crest)." [PMID:3596014] +synonym: "C1" RELATED [] +synonym: "D2.1.2" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005090 ! blastomere D2.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005102 +name: blastomere D2.2.1 +def: "Blastomere which lies lateral to blastomere D2.1.1 in the fourth tier of blastomeres. It contributes cells to the cranial ganglia, neural crest, spinal cord, fin epidermis, branchial mesoderm, heart, somites, pharynx, foregut, liver, and hindgut." [PMID:3596014] +synonym: "D2" RELATED [] +synonym: "D2.2.1" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005091 ! blastomere D2.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005103 +name: blastomere D2.2.2 +def: "Blastomere which lies lateral to blastomere D2.1.2, anterior to its sister cell, blastomere D2.2.1, in the third tier of blastomeres. It contributes cells to the epidermis, neural crest, brain, spinal cord, head mesoderm, somites, pronephric kidney, lateral plate mesoderm, tail fin mesenchyme, foregut, hindgut, with occasional cells in the liver and proctodeum observed." [PMID:3596014] +synonym: "C2" RELATED [] +synonym: "D2.2.2" RELATED [] +is_a: XAO:0005112 ! dorsal vegetal hemisphere blastomere +relationship: develops_from XAO:0005091 ! blastomere D2.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005104 +name: blastomere V1.1.1 +def: "Blastomere which lies adjacent to the prospective ventral midline in the first tier of blastomeres. It contributes to epidermal and placodal derivatives including the epidermis, lens, cement gland, cranial ganglia, otic vesicle, neural crest, Rohon-Beard neurons, and spinal cord (but no other CNS structures). It also contributes to the pharyngeal mesoderm, heart, somites, pronephric kidney, lateral plate mesoderm and tail fin mesenchymes, and a few cells in the gut." [PMID:3596014] +synonym: "A4" RELATED [] +synonym: "V1.1.1" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005092 ! blastomere V1.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005105 +name: blastomere V1.1.2 +def: "Blastomere which lies adjacent to the prospective ventral midline, posterior to its sister cell, blastomere V1.1.1, in the second tier of blastomeres. It contributes to trunk epidermis and neural crest cells, Rohon-Beard neurons, somites, the pronephric kidney, lateral plate mesoderm, tail fin mesenchyme, hindgut and proctodeum." [PMID:3596014] +synonym: "B4" RELATED [] +synonym: "V1.1.2" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005092 ! blastomere V1.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005106 +name: blastomere V1.2.1 +def: "Blastomere which lies lateral to blastomere V1.1.1 and is in the first tier of blastomeres. It contributes to many ectodermal structures including the epidermis, lens, cranial ganglia, otic vesicle, neural crest, olfactory placode, cement gland, retina, brain, and spinal cord. It also contributes cells to the pharyngeal mesoderm, head mesenchyme, heart, somites, pronephric kidney, lateral plate mesoderm and tail fin mesenchyme, archenteron roof, with occasional cells in the foregut, liver, hindgut and proctodeum." [PMID:3596014] +synonym: "A3" RELATED [] +synonym: "V1.2.1" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005093 ! blastomere V1.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005107 +name: blastomere V1.2.2 +def: "Blastomere which lies lateral to blastomere V1.1.2, posterior to its sister cell, blastomere V1.2.1, in the second tier of blastomeres. It contributes to the epidermis, fins, cranial ganglia, otic vesicle, central nervous system, neural crest, and somites, with occasional cells in the pharyngeal mesoderm, head mesenchyme, hindgut, and proctodeum." [PMID:3596014] +synonym: "B3" RELATED [] +synonym: "V1.2.2" RELATED [] +is_a: XAO:0005115 ! ventral animal hemisphere blastomere +relationship: develops_from XAO:0005093 ! blastomere V1.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005108 +name: blastomere V2.1.1 +def: "Blastomere which lies adjacent to the prospective, ventral midline in the fourth tier of blastomeres. It contributes a few cells to the epidermis, neural crest and spinal cord, and a large number of cells to the somites, pronephric kidney, lateral plate mesoderm, tail fin mesenchyme, hindgut, and proctodeum." [PMID:3596014] +synonym: "D4" RELATED [] +synonym: "V2.1.1" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005094 ! blastomere V2.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005109 +name: blastomere V2.1.2 +def: "Blastomere which lies adjacent to the prospective ventral midline, anterior to its sister cell, blastomere V2.1.1, in the third tier of blastomeres. It contributes cells to the epidermis, neural crest, spinal cord, somites, tail, hindgut and proctodeum." [PMID:3596014] +synonym: "C4" RELATED [] +synonym: "V2.1.2" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005094 ! blastomere V2.1 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005110 +name: blastomere V2.2.1 +def: "Blastomere which lies lateral to blastomere V2.1.1, in the fourth tier of blastomeres. It contributes cells to the epidermis and neural crest, spinal cord, somites, foregut, hindgut, and fewer cells to the head, pharyngeal mesoderm and proctodeum." [PMID:3596014] +synonym: "D3" RELATED [] +synonym: "V2.2.1" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005095 ! blastomere V2.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005111 +name: blastomere V2.2.2 +def: "Blastomere which lies lateral to blastomere V2.1.2, anterior to its sister cell, blastomere V2.2.1, in the third tier of blastomeres. It contributes cells to the epidermis, tail fin, cranial ganglia, neural crest, hindbrain, spinal cord, otic vesicle, pharyngeal mesoderm, somites, foregut, hindgut, archenteron roof, and proctodeum." [PMID:3596014] +synonym: "C3" RELATED [] +synonym: "V2.2.2" RELATED [] +is_a: XAO:0005114 ! ventral vegetal hemisphere blastomere +relationship: develops_from XAO:0005095 ! blastomere V2.2 +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000016 ! NF stage 6 (32-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005112 +name: dorsal vegetal hemisphere blastomere +def: "Blastomere that is any of blastomeres D2.1 and D2.2 and their children cells after division, D2.1.1, D2.1.2, D2.2.1 and D2.2.2, on the left and right sides of embryo." [PMID:3596014] +synonym: "DVHB" EXACT [] +is_a: XAO:0000279 ! vegetal blastomere +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005113 +name: dorsal animal hemisphere blastomere +def: "Blastomere that is any of blastomeres D1.1 and D1.2 and their children cells after division, D1.1.1, D1.1.2, D1.2.1 and D1.2.2, on the left and right sides of embryo." [PMID:3596014] +synonym: "DAHB" EXACT [] +is_a: XAO:0000200 ! animal blastomere +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005114 +name: ventral vegetal hemisphere blastomere +def: "Blastomere that is any of blastomeres V2.1 and V2.2 and their children cells after division, V2.1.1, V2.1.2, V2.2.1 and V2.2.2, on the left and right sides of embryo." [PMID:3596014] +synonym: "VVHB" EXACT [] +is_a: XAO:0000279 ! vegetal blastomere +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005115 +name: ventral animal hemisphere blastomere +def: "Blastomere that is any of blastomeres V1.1 and V1.2 and their children cells after division, V1.1.1, V1.1.2, V1.2.1 and V1.2.2, on the left and right sides of embryo." [PMID:3596014] +synonym: "VAHB" EXACT [] +is_a: XAO:0000200 ! animal blastomere +relationship: end_stage XAO:1000016 ! NF stage 6 (32-cell) +relationship: start_stage XAO:1000015 ! NF stage 5 (16-cell) +created_by: eriksegerdell +creation_date: 2016-08-16T20:28:11Z + +[Term] +id: XAO:0005116 +name: melanotrope +def: "A cell in the pituitary gland (hypophysis) that generates melanocyte-stimulating hormone from its precursor polypeptide, pro-opiomelanocortin (POMC)." [http:en.wikipedia.org/wiki/Melanotroph] +synonym: "melanocyte stimulating hormone secreting cell" EXACT [] +synonym: "melanotrope cell" EXACT [] +synonym: "melanotroph" EXACT [] +xref: CL:0000440 +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000017 ! hypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005117 +name: germinal granule +def: "A characteristic, electrondense germ plasm organelle encapsulating the cytoplasmic face of the nuclear envelope of the cells destined to the germline fate." [http://en.wikipedia.org/wiki/Granule_(cell_biology)] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000233 ! germ plasm +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005118 +name: ooplasm +def: "The cytoplasm of the oocyte." [http://medical-dictionary.thefreedictionary.com/ooplasm] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005119 +name: oocyte cortex +def: "Cell component comprising the outer layers of the oocyte." [XAO:EJS] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005120 +name: endoplasmic reticulum +def: "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." [GO:0005783] +synonym: "ER" EXACT [] +xref: GO:0005783 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005121 +name: prime meridian +def: "Embryonic region which is specified to form the head of the embryo." [XAO:curators] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: part_of XAO:0000113 ! embryo +relationship: start_stage XAO:1000001 ! NF stage 1 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005122 +name: microtubule +def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [GO:0005874] +xref: GO:0005874 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005123 +name: vegetal cortex +def: "Cell component comprising the outer layers of the vegetal region of the oocyte." [XAO:EJS] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0005119 ! oocyte cortex +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005124 +name: pulmonary epithelium +def: "The epithelial layer of the lung." [UBERON:0000115] +synonym: "epithelial tissue of lung" RELATED [] +synonym: "epithelium of lung" RELATED [] +synonym: "lung epithelial tissue" RELATED [] +synonym: "lung epithelium" RELATED [] +xref: UBERON:0000115 +is_a: XAO:0003045 ! epithelium +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000119 ! lung +relationship: part_of XAO:0001002 ! lung primordium +relationship: part_of XAO:0005140 ! lung bud +relationship: start_stage XAO:1000046 ! NF stage 31 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005125 +name: ventral foregut +def: "The ventral part of the foregut." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005126 +name: dorsal foregut +def: "The dorsal part of the foregut." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005127 +name: anterior foregut +def: "Embryonic structure that consists of the anterior part of the foregut and develops into the esophagus and trachea." [XAO:curators] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005128 +name: posterior foregut +def: "The posterior part of the foregut." [XAO:EJS] +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005129 +name: proximal stomach +def: "The section of the stomach comprising the cardia, fundus, and stomach body." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000128 ! stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005130 +name: distal stomach +def: "The section of the stomach comprising the antrum and pylorus." [XAO:EJS] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005128 ! posterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000128 ! stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005131 +name: astrocyte +def: "A characteristically star-shaped type of glial cell found in the optic nerve, brain and spinal cord. They have many processes, giving them their star shape, which terminate in structures called end-feet. They are the most numerous glial cell in the central nervous system and can behave like phagocytes in the CNS during metamorphosis." [CL:0000127, XAO:curators] +synonym: "astrocytic glia" EXACT [] +xref: CL:0000127 +is_a: XAO:0004308 ! glial cell +relationship: develops_from XAO:0005032 ! neural stem cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005132 +name: astrocyte end-foot +def: "The terminal process of an astrocyte." [GO:0097450] +synonym: "astrocyte end-feet" RELATED PLURAL [] +synonym: "astrocyte endfeet" RELATED PLURAL [] +synonym: "astrocyte endfoot" EXACT [] +xref: GO:0097450 +is_a: XAO:0004290 ! cell part +relationship: develops_from XAO:0005131 ! astrocyte +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005131 ! astrocyte +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005133 +name: oligodendrocyte +def: "A class of large neuroglial (macroglial) cells in the central nervous system that form the insulating myelin sheath of axons." [CL:0000128] +xref: CL:0000128 +is_a: XAO:0004308 ! glial cell +relationship: develops_from XAO:0005032 ! neural stem cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: part_of XAO:0000020 ! spinal cord +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005134 +name: microglial cell +def: "The smallest glial cell type in the central nervous system, cells of this type actively detect inflammatory responses/infection. They transform to a phagocytotic form, actively removing infective agents, and thus can present antigens to immune system cells." [XAO:curators] +synonym: "microglia" EXACT [] +xref: CL:0000129 +is_a: XAO:0004308 ! glial cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000038 ! NF stage 22 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005135 +name: enteroendocrine cell +def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [CL:0000164] +xref: CL:0000164 +is_a: XAO:0003247 ! endocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell +creation_date: 2016-12-06T18:00:00Z + +[Term] +id: XAO:0005136 +name: dorsal involuting marginal zone +def: "Tissue which during gastrulation involutes into the interior of the embryo, where its deep mesenchymal cells form the notochordal and somitic mesoderm and its superficial epithelial cells form the endodermal roof of the archenteron." [PMID:7588048] +synonym: "DIMZ" EXACT [] +synonym: "dorsal IMZ" EXACT [] +is_a: XAO:0000068 ! marginal zone +relationship: end_stage XAO:1000022 ! NF stage 12 +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005137 +name: monociliated cell +def: "A ciliated cell that has a single cilium." [XAO:EJS] +is_a: XAO:0005017 ! ciliated cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000094 ! gastrocoel roof plate +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005138 +name: subcortical cytoplasm +def: "The cytoplasm beneath the outer layers of the oocyte." [XAO:EJS] +synonym: "sub-cortical cytoplasm" EXACT [] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000092 ! mature egg stage +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005139 +name: multiciliated cell +def: "A ciliated cell that has more than one cilium." [XAO:EJS] +is_a: XAO:0005017 ! ciliated cell +relationship: develops_from XAO:0005180 ! multiciliated cell precursor +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005140 +name: lung bud +def: "A structure derived from the foregut that becomes a lung." [UBERON:0000118] +xref: UBERON:0000118 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0001002 ! lung primordium +relationship: end_stage XAO:1000065 ! NF stage 53 +relationship: part_of XAO:0000117 ! respiratory system +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005141 +name: pars externa of the stapes +def: "A cartilaginous extension of the stapes that expands into a cartilaginous tympanic disk." [PMID:20953303] +synonym: "extracolumella" EXACT [] +synonym: "extrastapes" EXACT [] +synonym: "pars externa" BROAD [] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004310 ! stapes +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005142 +name: pars media of the stapes +def: "The bony part of the stapes which forms the shaft. It is shaped like a bent rod: its distal half is firmly embedded within the tympanic disk, extending from the disk center caudally and dorsally, turning inwards, until it reaches the oval window at a shallow angle." [PMID:20953303] +synonym: "pars media" BROAD [] +is_a: XAO:0004276 ! bone element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004310 ! stapes +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005143 +name: pars interna of the stapes +def: "A cartilaginous component of the stapes that is firmly attached to the proximal end of the pars media. It lies within the oval window and forms the stapes footplate." [PMID:20953303] +synonym: "pars interna" BROAD [] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004310 ! stapes +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005144 +name: footplate of the stapes +def: "That part of the stapes lying within the oval window, formed from the stapes pars interna." [PMID:20953303] +synonym: "footplate" BROAD [] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004310 ! stapes +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005145 +name: fundus +def: "The section of the stomach which lies between the cardia and the stomach body, and contains the fundic glands." [http://en.wikipedia.org/wiki/Stomach, UBERON:0001160] +synonym: "fundic stomach" EXACT [] +synonym: "fundus of stomach" EXACT [] +synonym: "gastric fundus" EXACT [] +xref: UBERON:0001160 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005129 ! proximal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005129 ! proximal stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005146 +name: oval window +def: "Entrance to the inner ear in the lateral wall of the otic capsule, which contains the footplate of the stapes." [PMID:20953303] +synonym: "foramen ovale" RELATED [] +xref: UBERON:0002501 +is_a: XAO:0003190 ! anatomical space +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005225 ! otic capsule +relationship: start_stage XAO:1000055 ! NF stage 43 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005147 +name: parotic crest +def: "Cartilaginous extension of the prootic bone which overlies the middle ear region." [PMID:20953303] +is_a: XAO:0004013 ! cartilage element +relationship: develops_from XAO:0005314 ! prootic bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003059 ! chondrocranium +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005148 +name: m. depressor mandibulae +def: "A muscle acting to open the lower jaw, which runs from the caudal otic region downwards, passing over the stapes." [PMID:20953303] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005149 +name: m. levator scapulae superior +def: "Superior aspect of the cranial muscle that passes between the otic capsule and the scapula. It originates on the otic capsule just caudal to the oval window." [PMID:20953303] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005150 +name: m. levator scapulae inferior +def: "Inferior aspect of the cranial muscle that passes between the otic capsule and the scapula. It originates on the otic capsule just caudal to the oval window." [PMID:20953303] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005151 +name: m. petrohyoideus +def: "A long, strap-like muscle that originates mainly from the parotic crest, passes over the stapes and ultimately inserts on the ventral surface of the larynx." [PMID:20953303] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005152 +name: m. cucullaris +def: "A muscle that originates on the otic capsule and adjacent tympanic annulus, and inserts on the pectoral girdle." [PMID:20953303] +is_a: XAO:0004322 ! cranial muscle +relationship: develops_from XAO:0000053 ! head mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005153 +name: tympanic annulus +def: "The oval shaped cartilaginous ring that supports the cartilaginous tympanic disk." [PMID:20953303] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: start_stage XAO:1000059 ! NF stage 47 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005154 +name: plasma membrane +def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [GO:0005886] +synonym: "cell membrane" EXACT [] +synonym: "cellular membrane" EXACT [] +synonym: "cytoplasmic membrane" EXACT [] +synonym: "plasmalemma" EXACT [] +xref: GO:0005886 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I +created_by: eriksegerdell +creation_date: 2017-03-20T17:24:29Z + +[Term] +id: XAO:0005155 +name: archenteron roof midline +def: "Anatomical line that divides the archenteron roof into right and left halves." [XAO:EJS] +is_a: XAO:0004003 ! anatomical line +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000094 ! gastrocoel roof plate +relationship: start_stage XAO:1000020 ! NF stage 10 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005156 +name: stomach body +def: "The section of the stomach which lies between the fundus and the pyloric antrum." [UBERON:0001161] +synonym: "body of stomach" EXACT [] +synonym: "gastric body" EXACT [] +xref: UBERON:0001161 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005129 ! proximal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005129 ! proximal stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005157 +name: antrum +def: "The section of the stomach which lies between the stomach body and pylorus, and that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells." [UBERON:0001165] +synonym: "antrum of stomach" EXACT [] +synonym: "pyloric antrum" EXACT [] +xref: UBERON:0001165 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005130 ! distal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005130 ! distal stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005158 +name: pylorus +def: "The stomach tissue region which surrounds and controls the distal outlet of the stomach, which opens into the duodenum, and contains the pyloric glands." [ISBN:9781461348764, UBERON:0001166] +synonym: "pyloric stomach" EXACT [] +xref: UBERON:0001166 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005130 ! distal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005130 ! distal stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005159 +name: cardia +def: "The section of the stomach which is attached to the esophagus and contains the cardiac glands." [ISBN:9781461348764, UBERON:0001162] +synonym: "cardia of stomach" EXACT [] +synonym: "cardiac stomach" EXACT [] +synonym: "gastric cardia" EXACT [] +xref: UBERON:0001162 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0005129 ! proximal stomach +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005129 ! proximal stomach +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2016-12-09T17:00:00Z + +[Term] +id: XAO:0005160 +name: prepollex +def: "A tiny skeletal element adjacent to the anterior-most digit in the autopod in the developing forelimb, possibly representing a vestigal digit." [XAO:curators] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004299 ! hand +relationship: start_stage XAO:1000068 ! NF stage 56 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005161 +name: prehallux +def: "A tiny skeletal element adjacent to the anterior-most digit in the autopod in the developing hindlimb (i.e., hindlimb digit 5), possibly representing a vestigal 6th digit in Xenopus." [XAO:curators] +is_a: XAO:0004013 ! cartilage element +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004300 ! foot +relationship: start_stage XAO:1000067 ! NF stage 55 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005162 +name: mandibular arch skeleton +def: "Skeletal subdivision comprising the skeletal elements of the mandibular arch." [XAO:EJS] +xref: UBERON:0001708 +is_a: XAO:0004289 ! skeletal subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003176 ! splanchnocranium +relationship: start_stage XAO:1000040 ! NF stage 24 +created_by: eriksegerdell +creation_date: 2016-09-03T19:21:41Z + +[Term] +id: XAO:0005163 +name: thoracic region +def: "A region of the embryo that is located broadly around the heart, but ventral to the pharyngeal region, posterior to the cement gland, and anterior to the endoderm or organs of endodermal origin (foregut, liver and lung primordia)." [XAO:curators] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000044 ! NF stage 28 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005164 +name: alpha cell +def: "A type of endocrine cell in the pancreatic islets of the pancreas. They make up some of the islet cells synthesizing and secreting the peptide hormone glucagon, which elevates the glucose levels in the blood." [XAO:curators] +synonym: "alpha cells" RELATED PLURAL [] +synonym: "alpha-cell" EXACT [] +synonym: "alpha-cells" RELATED PLURAL [] +synonym: "pancreatic A cell" RELATED [] +xref: CL:0000171 +is_a: XAO:0005135 ! enteroendocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000159 ! islets of Langerhans +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005165 +name: beta cell +def: "A type of cell that is found in the pancreatic islets of the pancreas and secretes insulin." [XAO:curators] +synonym: "beta cells" RELATED PLURAL [] +synonym: "beta-cell" EXACT [] +synonym: "beta-cells" RELATED PLURAL [] +synonym: "type B pancreatic cell" RELATED [] +xref: CL:0000169 +is_a: XAO:0005135 ! enteroendocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000159 ! islets of Langerhans +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005166 +name: delta cell +def: "Somatostatin-producing cell that is found in the stomach, intestine and the pancreatic islets." [XAO:curators] +synonym: "D cell" RELATED [] +synonym: "D-cell" RELATED [] +synonym: "delta cells" RELATED PLURAL [] +synonym: "delta-cell" EXACT [] +synonym: "delta-cells" RELATED PLURAL [] +synonym: "type D enteroendocrine cell" RELATED [] +xref: CL:0000502 +is_a: XAO:0005135 ! enteroendocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000125 ! alimentary system +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005167 +name: epsilon cell +def: "A type of endocrine cell that is found in the islets of Langerhans and produces the hormone ghrelin." [XAO:curators] +synonym: "epsilon cells" RELATED PLURAL [] +synonym: "epsilon-cell" EXACT [] +synonym: "epsilon-cells" RELATED PLURAL [] +is_a: XAO:0005135 ! enteroendocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000159 ! islets of Langerhans +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005168 +name: gamma cell +def: "A type of cell that produces pancreatic polypeptides in the pancreatic islets (the islets of Langerhans) of the pancreas." [XAO:curators] +synonym: "PP cell" RELATED [] +synonym: "pp-cell" RELATED [] +is_a: XAO:0005135 ! enteroendocrine cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000159 ! islets of Langerhans +relationship: start_stage XAO:1000051 ! NF stage 39 +created_by: eriksegerdell +creation_date: 2016-11-16T18:07:16Z + +[Term] +id: XAO:0005169 +name: left-right organizer primordium +def: "The presumptive cells of the organizing region which is formed by the posterior layer of the gastrocoel roof plate during early neurulation." [XAO:EJS] +synonym: "left-right organiser primordium" EXACT [] +is_a: XAO:0003043 ! primordium +relationship: develops_from XAO:0000076 ! involuting marginal zone epithelial layer +relationship: end_stage XAO:1000026 ! NF stage 16 +relationship: part_of XAO:0000094 ! gastrocoel roof plate +relationship: start_stage XAO:1000033 ! NF stage 12.5 +created_by: eriksegerdell +creation_date: 2017-03-30T16:43:56Z + +[Term] +id: XAO:0005170 +name: left-right organizer +def: "Region which is formed by the posterior layer of the gastrocoel roof plate during neurulation and has functionality in determining organ and axis symmetry." [XAO:curators] +synonym: "left-right organiser" EXACT [] +synonym: "LRO" EXACT [] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0005169 ! left-right organizer primordium +relationship: end_stage XAO:1000050 ! NF stage 37 and 38 +relationship: part_of XAO:0000094 ! gastrocoel roof plate +relationship: start_stage XAO:1000027 ! NF stage 17 +created_by: eriksegerdell +creation_date: 2017-03-30T16:45:24Z + +[Term] +id: XAO:0005171 +name: fin margin +def: "The outermost extent of a fin, comprising a region of high cell replication during anterior-posterior axis extension throughout the tadpole stages." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000028 ! epidermis +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000002 ! fin +relationship: start_stage XAO:1000042 ! NF stage 26 +created_by: eriksegerdell +creation_date: 2017-04-11T16:34:29Z + +[Term] +id: XAO:0005172 +name: left blastomere +def: "The blastomere of the future left side of the embryo at the 2-cell stage." [XAO:EJS] +is_a: XAO:0003016 ! blastomere +relationship: end_stage XAO:1000011 ! NF stage 2 (2-cell) +relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005173 +name: right blastomere +def: "The blastomere of the future right side of the embryo at the 2-cell stage." [XAO:EJS] +is_a: XAO:0003016 ! blastomere +relationship: end_stage XAO:1000011 ! NF stage 2 (2-cell) +relationship: start_stage XAO:1000011 ! NF stage 2 (2-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005174 +name: left-dorsal blastomere +def: "The blastomere of the future left-dorsal portion of the embryo at the 4-cell stage." [XAO:EJS] +synonym: "LD" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0005172 ! left blastomere +relationship: end_stage XAO:1000013 ! NF stage 3 (4-cell) +relationship: start_stage XAO:1000013 ! NF stage 3 (4-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005175 +name: right-dorsal blastomere +def: "The blastomere of the future right-dorsal portion of the embryo at the 4-cell stage." [XAO:EJS] +synonym: "RD" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0005173 ! right blastomere +relationship: end_stage XAO:1000013 ! NF stage 3 (4-cell) +relationship: start_stage XAO:1000013 ! NF stage 3 (4-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005176 +name: left-ventral blastomere +def: "The blastomere of the future left-ventral portion of the embryo at the 4-cell stage." [XAO:EJS] +synonym: "LV" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0005172 ! left blastomere +relationship: end_stage XAO:1000013 ! NF stage 3 (4-cell) +relationship: start_stage XAO:1000013 ! NF stage 3 (4-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005177 +name: right-ventral blastomere +def: "The blastomere of the future right-ventral portion of the embryo at the 4-cell stage." [XAO:EJS] +synonym: "RV" RELATED [] +is_a: XAO:0003016 ! blastomere +relationship: develops_from XAO:0005173 ! right blastomere +relationship: end_stage XAO:1000013 ! NF stage 3 (4-cell) +relationship: start_stage XAO:1000013 ! NF stage 3 (4-cell) +created_by: eriksegerdell +creation_date: 2017-04-13T17:00:00Z + +[Term] +id: XAO:0005178 +name: monociliated epidermal cell +def: "A ciliated epidermal cell that has a single cilium." [XAO:curators] +is_a: XAO:0000031 ! ciliated epidermal cell +is_a: XAO:0005137 ! monociliated cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-04-14T17:17:00Z + +[Term] +id: XAO:0005179 +name: multiciliated epidermal cell +def: "A ciliated epidermal cell that has more than one cilium." [XAO:curators] +synonym: "MCC" RELATED [] +is_a: XAO:0000031 ! ciliated epidermal cell +is_a: XAO:0005139 ! multiciliated cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-04-14T17:17:00Z + +[Term] +id: XAO:0005180 +name: multiciliated cell precursor +def: "Cell type that gives rise to multiciliated cells." [XAO:EJS] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:1000020 ! NF stage 10 +relationship: start_stage XAO:1000017 ! NF stage 7 +created_by: eriksegerdell +creation_date: 2017-04-14T17:17:00Z + +[Term] +id: XAO:0005181 +name: ascending interneuron +def: "An interneuron which grows from the soma in an ascending (from tail to head) direction." [PMID:29051550] +synonym: "aIN" EXACT [] +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-11-10T17:00:00Z + +[Term] +id: XAO:0005182 +name: descending interneuron +def: "An interneuron which grows from the soma in a descending (from head to tail) direction." [PMID:29051550] +synonym: "dIN" EXACT [] +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-11-10T17:00:00Z + +[Term] +id: XAO:0005183 +name: commissural interneuron +def: "An interneuron which starts to grow on one side of the body and navigates in the ventral direction." [PMID:29051550] +synonym: "cIN" EXACT [] +is_a: XAO:0004267 ! interneuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-11-10T17:00:00Z + +[Term] +id: XAO:0005184 +name: dorsolateral ascending neuron +def: "An ascending neuron, originating in the spinal cord, that is involved in the touch sensory pathway and lies adjacent to the Rohon-Beard neurons and close to the roof plate of the spinal cord." [PMID:29051550] +synonym: "dla" RELATED [] +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-11-15T17:00:00Z + +[Term] +id: XAO:0005185 +name: dorsolateral commissural neuron +def: "A commissural neuron, originating in the spinal cord, that is involved in the touch sensory pathway and lies adjacent to the Rohon-Beard neurons and close to the roof plate of the spinal cord." [PMID:29051550] +synonym: "dlc" RELATED [] +is_a: XAO:0003023 ! neuron +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 +created_by: eriksegerdell +creation_date: 2017-11-15T17:00:00Z + +[Term] +id: XAO:0005186 +name: adenohypophysis +def: "The glandular, anterior lobe of the pituitary gland (hypophysis). It regulates several physiological processes including stress, growth, and reproduction." [https://en.wikipedia.org/wiki/Anterior_pituitary] +synonym: "anterior hypophysis" EXACT [] +synonym: "anterior lobe of pituitary gland" EXACT [] +synonym: "anterior pituitary" EXACT [] +synonym: "pars anterior" RELATED [] +xref: UBERON:0002196 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004208 ! adenohypophyseal placode +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000017 ! hypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2017-11-17T16:49:43Z + +[Term] +id: XAO:0005187 +name: neurohypophysis +def: "The posterior lobe of the pituitary gland (hypophysis). It is largely a collection of axonal projections from the hypothalamus that terminate behind the anterior pituitary, and serve as a site for the secretion of neurohypophysial hormones (oxytocin and vasopressin) directly into the blood. It is not glandular as is the anterior pituitary." [https://en.wikipedia.org/wiki/Posterior_pituitary] +synonym: "posterior hypophysis" EXACT [] +synonym: "posterior lobe of pituitary gland" EXACT [] +synonym: "posterior pituitary" EXACT [] +xref: UBERON:0002198 +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0004210 ! infundibulum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000017 ! hypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2017-11-17T16:49:56Z + +[Term] +id: XAO:0005188 +name: pars distalis +def: "Structure which comprises the majority of the anterior pituitary (adenohypophysis) and where the bulk of pituitary hormone production occurs." [https://en.wikipedia.org/wiki/Anterior_pituitary] +synonym: "pars distalis of adenohypophysis" EXACT [] +xref: UBERON:0006964 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005186 ! adenohypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2017-11-17T16:49:59Z + +[Term] +id: XAO:0005189 +name: pars nervosa +def: "Structure which constitutes the majority of the posterior pituitary (neurohypophysis) and that is the storage site of oxytocin and vasopressin." [https://en.wikipedia.org/wiki/Posterior_pituitary] +synonym: "neural lobe of neurohypophysis" EXACT [] +synonym: "posterior lobe of neurohypophysis" EXACT [] +xref: UBERON:0003217 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005187 ! neurohypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2017-11-17T16:50:21Z + +[Term] +id: XAO:0005190 +name: pars intermedia +def: "The boundary between the anterior and posterior lobes of the pituitary (hypophysis). It contains three types of cells: basophils, chromophobes, and colloid-filled cysts. The cysts are the remainder of Rathke's pouch." [https://en.wikipedia.org/wiki/Pars_intermedia] +synonym: "pars intermedia of adenohypophysis" EXACT [] +synonym: "pars intermedis" EXACT [] +xref: UBERON:0002432 +is_a: XAO:0004486 ! organ part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000017 ! hypophysis +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2017-11-17T16:51:54Z + +[Term] +id: XAO:0005191 +name: ethmoid bone +def: "An unpaired bone in the skull that separates the nasal cavity from the brain. It is located at the roof of the nose, between the two orbits." [https://en.wikipedia.org/wiki/Ethmoid_bone] +synonym: "ethmoid" BROAD [] +synonym: "ethmoidal bone" EXACT [] +synonym: "os ethmoidale" EXACT [] +xref: UBERON:0001679 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004023 ! craniofacial skeleton +relationship: part_of XAO:0005192 ! ethmoid region +relationship: start_stage XAO:1000057 ! NF stage 45 +created_by: eriksegerdell +creation_date: 2018-01-16T17:00:00Z + +[Term] +id: XAO:0005192 +name: ethmoid region +def: "Anatomical cluster comprising the most anterior region of the braincase and providing structural support for the peripheral olfactory organ." [UBERON:0011241] +xref: UBERON:0011241 +is_a: XAO:0003160 ! anatomical cluster +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003075 ! cranium +relationship: start_stage XAO:1000052 ! NF stage 40 +created_by: eriksegerdell +creation_date: 2018-01-17T17:00:00Z + +[Term] +id: XAO:0005193 +name: lateral nasal prominence +def: "The lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo. It separates the olfactory pit from the developing eye." [UBERON:0004067] +synonym: "lateral nasal swelling" RELATED [] +synonym: "prominentia nasalis lateralis" EXACT [] +xref: UBERON:0004067 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2018-01-17T17:00:00Z + +[Term] +id: XAO:0005194 +name: medial nasal prominence +def: "The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo." [UBERON:0004068] +synonym: "medial nasal swelling" RELATED [] +synonym: "nasomedial prominence" RELATED [] +xref: UBERON:0004068 +is_a: XAO:0003042 ! embryonic structure +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000023 ! NF stage 13 +created_by: eriksegerdell +creation_date: 2018-01-17T17:00:00Z + +[Term] +id: XAO:0005195 +name: enteric nervous system +def: "The mesh-like system of enteric neurons that innervate the gastrointestinal tract, with neurons embedded in the lining of the gastrointestinal system, beginning at the esophagus and extending down to the cloaca. The ENS can and does operate independently of the brain and the spinal cord." [https://en.wikipedia.org/wiki/Enteric_nervous_system] +synonym: "ENS" EXACT [] +synonym: "intrinsic nervous system" RELATED [] +xref: UBERON:0002005 +is_a: XAO:0000177 ! nervous system +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005196 +name: neutrophil +def: "A type of blood cell which is part of the innate immune system and is quickly recruited to sites of injury." [XAO:curators] +synonym: "neutrocyte" RELATED [] +xref: CL:0000775 +is_a: XAO:0003239 ! circulating cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000124 ! blood +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0005197 +name: lateral preplacodal ectoderm +def: "One of the 3 domains of the U-shaped preplacodal ectoderm, lying between the anterior PPE and posterior PPE domains." [XAO:curators] +synonym: "lateral PPE" EXACT [] +synonym: "LPPE" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0004104 ! neural plate border +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0004092 ! preplacodal ectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005198 +name: cardiac atrium +def: "Cardiac chamber in which blood enters the heart." [UBERON:0002081] +xref: UBERON:0002081 +is_a: XAO:0003165 ! cavitated compound organ +relationship: develops_from XAO:0000337 ! endocardial tube +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0005199 +name: peripheral ganglion +def: "Type of ganglia in the trunk region that connect the central nervous system with organs, muscles, blood vessels and glands, and are exclusively derived from trunk neural crest cells." [PMID:11254347] +is_a: XAO:0000209 ! ganglion +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005200 +name: anatomical axis +def: "A straight line through space, intersecting an anatomical entity. Axis directions are defined in terms of axes." [BSPO:0000010] +is_a: XAO:0004003 ! anatomical line +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005201 +name: animal-vegetal axis +def: "An axis that extends from the animal end of an egg or early embryo to the opposite, vegetal end." [BSPO:0000199] +is_a: XAO:0005200 ! anatomical axis +relationship: end_stage XAO:1000021 ! NF stage 11 +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005202 +name: anterior-posterior axis +def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:0000013] +is_a: XAO:0005200 ! anatomical axis +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005203 +name: dorsal-ventral axis +def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:0000016] +is_a: XAO:0005200 ! anatomical axis +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005204 +name: left-right axis +def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:0000017] +is_a: XAO:0005200 ! anatomical axis +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005205 +name: anatomical side +def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:0000054] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005206 +name: anterior side +def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:0000055] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005207 +name: posterior side +def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:0000056] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005208 +name: dorsal side +def: "An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:0000063] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005209 +name: ventral side +def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:0000068] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005210 +name: left side +def: "The side of an organism that is left of the sagittal plane." [BSPO:0000000] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005211 +name: right side +def: "The side of an organism that is right of the sagittal plane." [BSPO:0000007] +is_a: XAO:0005205 ! anatomical side +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005212 +name: proximal-distal axis +def: "An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal)." [BSPO:0000015] +is_a: XAO:0005200 ! anatomical axis +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005213 +name: apical region +def: "Anatomical region located on the apical end on the body or body part." [BSPO:0000073] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005214 +name: axial region +def: "Anatomical region that runs down the center (axis) of the body, encompassing everything exept the limbs." [XAO:EJS] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005215 +name: basal region +def: "Anatomical region located basally on the body or body part." [BSPO:0000074] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005216 +name: anterior region +def: "Anatomical region anteriorly located on the body or body part." [BSPO:0000071] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005217 +name: posterior region +def: "Anatomical region posteriorly located on the body or body part." [BSPO:0000072] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005218 +name: dorsal region +def: "Anatomical region dorsally located on the body or body part." [BSPO:0000079] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005219 +name: ventral region +def: "Anatomical region ventrally located on the body or body part." [BSPO:0000084] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005220 +name: medial region +def: "Anatomical region medially located on the body or body part." [BSPO:0000083] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005221 +name: antero-dorsal region +def: "Anatomical region that overlaps the anterior and dorsal regions of a body or body part." [BSPO:0000026] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005222 +name: antero-ventral region +def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:0000027] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005223 +name: postero-dorsal region +def: "Anatomical region that overlaps the posterior and dorsal regions of the body or body part." [BSPO:0000030] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005224 +name: postero-ventral region +def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:0000035] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005225 +name: otic capsule +def: "The capsule surrounding the inner ear components." [XAO:MEF] +synonym: "ear capsule" RELATED [] +xref: UBERON:0004637 +is_a: XAO:0004017 ! endochondral element +relationship: develops_from XAO:0000006 ! otic vesicle +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000192 ! inner ear +relationship: part_of XAO:0003083 ! braincase and otic capsule skeleton +relationship: part_of XAO:0003175 ! otic region +relationship: start_stage XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:0005226 +name: migrating myoblast +def: "Any of the muscle precursor cells which emerge from the lower margin of the trunk somites, appear in a segmented pattern, and move through the lateral regions of the embryo to form the hypaxial muscle." [XAO:CJZ] +synonym: "migratory somitic cell" RELATED [] +is_a: XAO:0003015 ! myoblast +relationship: develops_from XAO:0000314 ! trunk somite +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0005227 +name: flexural organ +def: "Tissue that is the most anterior portion of the notochord and secretes Reissner's fiber-related proteins, including F-spondin." [PMID:9482230] +synonym: "FO" EXACT [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000205 ! axial mesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0005228 +name: efferent neuron +def: "A neuron that transmits nerve impulses away from the central nervous system to the muscles or glands." [XAO:EJS] +is_a: XAO:0003023 ! neuron +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005195 ! enteric nervous system +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005229 +name: afferent neuron +def: "A neuron that transmits nerve impulses to the central nervous system from sensory stimuli." [XAO:EJS] +is_a: XAO:0003023 ! neuron +relationship: develops_from XAO:0000048 ! neural crest +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005195 ! enteric nervous system +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005230 +name: larval alimentary system +def: "The alimentary system of a postembryonic, hatched or immature tadpole, prior to metamorphosis." [XAO:EJS] +is_a: XAO:0000125 ! alimentary system +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0005231 +name: cloacal sphincter +def: "The developing muscle surrounding the caudal end of the cloaca." [https://medical-dictionary.thefreedictionary.com/cloacal+sphincter] +is_a: XAO:0003037 ! multi-tissue structure +relationship: develops_from XAO:0001019 ! proctodeum +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000244 ! cloaca +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0005232 +name: ionocyte, alpha subtype +def: "One of the two types of proton-secreteing cells (PSC) in amphibian skin, which play an important role in ion transport, alpha-PSCs are characterised by expression of slc4a1 (ae1) and localization of H+v-ATPases at the apical plasma membrane." [PMID:21266406] +synonym: "alpha ionocyte" EXACT [] +synonym: "alpha-PSC" EXACT [] +synonym: "ICa" EXACT [] +is_a: XAO:0004085 ! ionocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005233 +name: ionocyte, beta subtype +def: "One of the two types of proton-secreteing cells (PSC) in amphibian skin, which play an important role in ion transport, beta-PSCs are characterised by expression of pendrin and localization of the H+v-ATPase cytosolically or basolaterally in the plasma membrane." [PMID:21266406] +synonym: "beta ionocyte" EXACT [] +synonym: "beta-PSC" EXACT [] +synonym: "ICb" EXACT [] +is_a: XAO:0004085 ! ionocyte +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005234 +name: small secretory cell +def: "One of the four cell types that are found in bilayered epithlium of the larval epidermis (the others being goblet cells, multicilliated cells, and ionocytes) and have an abundance of large apical secretory vesicles and secrete a glyocoprotein with antimicrobial properties." [PMID:24598166] +synonym: "SCC" EXACT [] +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000028 ! epidermis +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0005235 +name: dorsal telencephalon +def: "The dorsal part of the telencephalon." [XAO:EJS] +synonym: "dt" EXACT [] +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000012 ! telencephalon +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0005236 +name: intestinal stem cell +def: "Type of adult stem cells that are induced by thyroid hormone (TH) and, during intestinal remodeling during metamorphosis, newly generate the absorptive epithelium." [PMID:30430240] +synonym: "xenopus_anatomy" EXACT [] +is_a: XAO:0003054 ! stem cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000130 ! small intestine +relationship: start_stage XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:0005238 +name: obsolete rostral notochord +is_obsolete: true +replaced_by: XAO:0005423 + +[Term] +id: XAO:0005239 +name: obsolete caudal notochord +is_obsolete: true +replaced_by: XAO:0005424 + +[Term] +id: XAO:0005240 +name: regenerating lens +def: "Tissue of the lens that is re-growing after damage or amputation." [XAO:curators] +synonym: "lens" BROAD [] +is_a: XAO:0004059 ! regenerating tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004109 ! regenerating eye +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0005241 +name: superficial layer of neurectoderm +def: "Layer of neurectoderm that develops into the roof plate of the spinal cord." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000249 ! neural plate +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005242 +name: posterior neural fold +def: "The posterior portions of the U-shaped neural folds, the two longitudinal dorsal ridges caused by a folding up of the ectoderm, which appear on either side of the middle line of the early neurula embryo." [XAO:CJZ] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000038 ! NF stage 22 +relationship: part_of XAO:0000046 ! chordal neural plate +relationship: part_of XAO:0004087 ! neural fold +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0005243 +name: embryonic kidney +def: "A transient kidney that functions in embryos of amphibians (and fish) while the mesonephros (which continue to grow into adult kidneys) are developing and before they are fully functional." [XAO:curators] +synonym: "pronephros" RELATED [] +is_a: XAO:0003267 ! kidney +relationship: end_stage XAO:1000076 ! NF stage 64 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005244 +name: adult kidney +def: "Either of the pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine." [XAO:curators] +synonym: "mesonephros" RELATED [] +is_a: XAO:0003267 ! kidney +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0005245 +name: neurenteric canal +def: "The most posterior zone of the neural tube, first evident at NF stage 17, which develops where the neural tube passes into the archenteron roof around the dorsal blastoporal lip, becoming deeper during late neurula stages." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000050 ! mesoderm +relationship: end_stage XAO:1000044 ! NF stage 28 +relationship: part_of XAO:0000107 ! tail bud +relationship: part_of XAO:0003204 ! neural tube +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0005246 +name: migratory trunk neural crest cell +def: "Migratory neural crest cell that is part of the trunk neural crest." [XAO:EJS] +is_a: XAO:0004069 ! migratory neural crest cell +relationship: end_stage XAO:1000047 ! NF stage 32 +relationship: part_of XAO:0000319 ! trunk neural crest +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0005247 +name: hindgut endoderm +def: "Endoderm that is part of the hindgut." [XAO:EJS] +xref: UBERON:0003260 +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000104 ! hindgut +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005248 +name: dorsal posterior hindgut endoderm +def: "Dorsal part of the posterior hindgut endoderm." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0005250 ! posterior hindgut endoderm +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005249 +name: ventral posterior hindgut endoderm +def: "Ventral part of the posterior hindgut endoderm." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0005250 ! posterior hindgut endoderm +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005250 +name: posterior hindgut endoderm +def: "Posterior part of the hindgut endoderm." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0005247 ! hindgut endoderm +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005251 +name: anterior hindgut endoderm +def: "Anterior part of the hindgut endoderm." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0005247 ! hindgut endoderm +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005252 +name: obsolete left olfactory pit +is_obsolete: true +consider: XAO:0000275 + +[Term] +id: XAO:0005253 +name: obsolete right olfactory pit +is_obsolete: true +consider: XAO:0000275 + +[Term] +id: XAO:0005254 +name: apical junction complex +def: "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." [GO:0043296] +xref: GO:0043296 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003249 ! epithelial cell +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005255 +name: filopodium +def: "Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast, an axonal or dendritic growth cone, or a dendritic shaft." [GO:0030175] +xref: GO:0030175 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005256 +name: obsolete left eye +is_obsolete: true +consider: XAO:0000179 + +[Term] +id: XAO:0005257 +name: obsolete right eye +is_obsolete: true +consider: XAO:0000179 + +[Term] +id: XAO:0005258 +name: obsolete left inner ear +is_obsolete: true +consider: XAO:0000192 + +[Term] +id: XAO:0005259 +name: obsolete right inner ear +is_obsolete: true +consider: XAO:0000192 + +[Term] +id: XAO:0005260 +name: ventral trunk +def: "Part of the trunk located on the ventral side of the organism." [XAO:EJS] +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0005261 +name: posterior tail +def: "The posterior part of the tail." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0005262 +name: anterior dorsal fin +def: "The anterior part of the dorsal fin." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004063 ! dorsal fin +relationship: start_stage XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:0005263 +name: anterior neuroectoderm +def: "Neuroectoderm that is located on the anterior side of the organism." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000042 ! neuroectoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005264 +name: dorsal tail +def: "Part of the tail located on the dorsal side of the organism." [XAO:EJS] +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003026 ! tail +relationship: start_stage XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:0005265 +name: dorsal trunk +def: "Part of the trunk located on the dorsal side of the organism." [XAO:EJS] +is_a: XAO:0003013 ! organism subdivision +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003025 ! trunk +relationship: start_stage XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:0005266 +name: thrombocyte +def: "A cell type that produces platelets and coagulating factors that react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. In amphibians, embryonic and adult thrombocytes have different origins and potentially different gene expression markers." [https://en.wikipedia.org/wiki/Platelet, XAO:curators] +is_a: XAO:0003012 ! cell +relationship: develops_from XAO:0004473 ! ventral mesoderm +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000124 ! blood +relationship: part_of XAO:0001010 ! circulatory system +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005267 +name: embryonic thrombocyte +def: "A cell type that produces platelets and coagulating factors that react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot; and that, in embryos, emerge from the ventral mesoderm, just anterior to the ventral blood island. Embryonic thrombocytes are identified by cd41/itga2b.1 gene expression. Additional waves of emergence during development may occur but have not yet been described." [https://en.wikipedia.org/wiki/Platelet, XAO:curators] +synonym: "thrombocyte, embryonic" EXACT [] +is_a: XAO:0005266 ! thrombocyte +relationship: end_stage XAO:1000077 ! NF stage 65 +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005268 +name: adult thrombocyte +def: "A cell type that produces platelets and coagulating factors that react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot; and that, in adults, develop from hematopoietic stem cells." [https://en.wikipedia.org/wiki/Platelet, XAO:curators] +synonym: "thrombocyte, adult" EXACT [] +is_a: XAO:0005266 ! thrombocyte +relationship: develops_from XAO:0003055 ! hematopoietic stem cell +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000077 ! NF stage 65 + +[Term] +id: XAO:0005269 +name: regenerating pelvic girdle +def: "Pelvic girdle tissue that is re-growing after damage or amputation." [] {comment="XAO:EJS"} +is_a: XAO:0004059 ! regenerating tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004060 ! blastema +relationship: start_stage XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:0005270 +name: obsolete left part of branchial arch skeleton +is_obsolete: true +consider: XAO:0003180 + +[Term] +id: XAO:0005271 +name: obsolete right part of branchial arch skeleton +is_obsolete: true +consider: XAO:0003180 + +[Term] +id: XAO:0005272 +name: obsolete left forelimb +is_obsolete: true +consider: XAO:0003030 + +[Term] +id: XAO:0005273 +name: obsolete right forelimb +is_obsolete: true +consider: XAO:0003030 + +[Term] +id: XAO:0005274 +name: obsolete left hindlimb +is_obsolete: true +consider: XAO:0003031 + +[Term] +id: XAO:0005275 +name: obsolete right hindlimb +is_obsolete: true +consider: XAO:0003031 + +[Term] +id: XAO:0005276 +name: obsolete left optic vesicle +is_obsolete: true +consider: XAO:0000228 + +[Term] +id: XAO:0005277 +name: obsolete right optic vesicle +is_obsolete: true +consider: XAO:0000228 + +[Term] +id: XAO:0005278 +name: obsolete left part of brain +is_obsolete: true +consider: XAO:0000010 + +[Term] +id: XAO:0005279 +name: obsolete right part of brain +is_obsolete: true +consider: XAO:0000010 + +[Term] +id: XAO:0005280 +name: ventro-lateral region +def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:0000085] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005281 +name: dorso-lateral region +def: "Anatomical region that overlaps the dorsal and lateral regions of a body or body part." [BSPO:0000080] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005282 +name: yolk platelet +def: "An organelle that contains yolk for consumption during embryogenesis." [XAO:MEF] +synonym: "YP" EXACT [] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000060 ! NF stage 48 +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000085 ! oocyte stage III + +[Term] +id: XAO:0005283 +name: non-neurogenic ectodermal placode +def: "Ectodermal placode that does not develop into a component of the nervous system." [UBERON:0011814] +xref: UBERON:0011814 +is_a: XAO:0000305 ! cranial placode +relationship: develops_from XAO:0004092 ! preplacodal ectoderm +relationship: end_stage XAO:1000054 ! NF stage 42 +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0005284 +name: sarcomere +def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GO:0030017] +xref: GO:0030017 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005311 ! myofibril +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005285 +name: spindle microtubule +def: "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." [GO:0005876] +xref: GO:0005876 +is_a: XAO:0005122 ! microtubule +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005286 +name: astral microtubule +def: "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." [GO:0000235] +xref: GO:0000235 +is_a: XAO:0005285 ! spindle microtubule +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005287 +name: jaw muscle primordium +def: "The presumptive cells of the jaw muscle." [XAO:EJS] +is_a: XAO:0004455 ! cranial muscle primordium +relationship: develops_from XAO:0000097 ! mandibular arch +relationship: develops_from XAO:0000098 ! hyoid arch +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: start_stage XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:0005288 +name: pial cell +def: "A cell of the pia mater, the delicate fibrous meningeal coverings of the CNS." [PMID:30993182] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005289 ! pia mater +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0005289 +name: pia mater +def: "The innermost delicate fibrous meningeal coverings of the CNS. It is closely adherent to the brain tissue and is composed of one to several layers of flattened, modified fibroblasts and the ECM (collagen and elastic fibers, etc.) they produce." [PMID:30993182] +synonym: "pia" RELATED [] +synonym: "pia matter" EXACT [] +xref: UBERON:0002361 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000010 ! brain +relationship: start_stage XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:0005290 +name: Roux spot +def: "The unpigmented maturation spot which indicates germinal vesicle breakdown and thus maturation of an oocyte." [PMID:30046, PMID:6540084] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:1000084 ! oocyte stage II +relationship: part_of XAO:0000256 ! oocyte +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005291 +name: buccopharyngeal membrane +def: "A 1-2 cell layer membrane comprising cells from the stomodeum and underlying endodermal layer. Perforation of this structure creates an opening connecting the external and the digestive tube which is essential for oral cavity formation." [PMID:16678148, PMID:28032936] +synonym: "oral plate membrane" EXACT [] +xref: UBERON:0006211 +is_a: XAO:0003042 ! embryonic structure +relationship: develops_from XAO:0000257 ! oral evagination +relationship: develops_from XAO:0000269 ! mouth primordium +relationship: end_stage XAO:1000052 ! NF stage 40 +relationship: part_of XAO:0000269 ! mouth primordium +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0005292 +name: nasociliary nerve +def: "Cephalic nerve that innervates the nasal cavity and the eye." [] {comment="XAO:EJS"} +synonym: "nervus nasociliaris" EXACT [] +xref: UBERON:0022300 +is_a: XAO:0005309 ! cephalic nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003092 ! trigeminal nerve +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005293 +name: maxillary nerve +def: "Cephalic nerve that innervates the maxillary sinus." [] {comment="XAO:EJS"} +synonym: "nervus maxillare" EXACT [] +xref: UBERON:0000377 +is_a: XAO:0005309 ! cephalic nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003092 ! trigeminal nerve +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005294 +name: mandibular nerve +def: "Cephalic nerve that innervates the lower jaw." [] {comment="XAO:EJS"} +synonym: "nervus mandibulare" EXACT [] +xref: UBERON:0000375 +is_a: XAO:0005309 ! cephalic nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003092 ! trigeminal nerve +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005295 +name: frontal nerve +def: "Cephalic nerve that is the largest branch of the ophthalmic division of the trigeminal nerve." [] {comment="XAO:EJS"} +synonym: "nervus frontalis" EXACT [] +xref: UBERON:0000942 +is_a: XAO:0005309 ! cephalic nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003092 ! trigeminal nerve +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005296 +name: adherens junction +def: "A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments." [GO:0005912] +xref: GO:0005912 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005297 +name: foregut epithelium +def: "The epithelium of the foregut." [XAO:MEF] +xref: UBERON:0015833 +is_a: XAO:0003200 ! gut epithelium +relationship: develops_from XAO:0004513 ! foregut endoderm +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:0005298 +name: tracheal epithelium +def: "The epithelium of the trachea." [XAO:MEF] +xref: UBERON:0001901 +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000118 ! trachea +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0005299 +name: esophageal epithelium +def: "The epithelium of the esophagus." [XAO:MEF] +xref: UBERON:0001976 +is_a: XAO:0003045 ! epithelium +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000127 ! esophagus +relationship: start_stage XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:0005300 +name: stomach epithelium +def: "The epithelium of the stomach." [XAO:MEF] +xref: UBERON:0001276 +is_a: XAO:0003200 ! gut epithelium +relationship: develops_from XAO:0000232 ! foregut +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000232 ! foregut +relationship: start_stage XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:0005301 +name: ventral endoderm +def: "Ventral region of early embryonic endoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005302 +name: posterior endoderm +def: "Posterior region of the developing endoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005303 +name: anterior endoderm +def: "Anterior region of the developing endoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0000090 ! endoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0000090 ! endoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005304 +name: dorsal endomesoderm +def: "Dorsal region of early embryonic endomesoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0003044 ! endomesoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005305 +name: ventral endomesoderm +def: "Ventral region of early embryonic endomesoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000034 ! NF stage 18 +relationship: part_of XAO:0003044 ! endomesoderm +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005306 +name: anterior endomesoderm +def: "Anterior region of the developing endomesoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003044 ! endomesoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005307 +name: posterior endomesoderm +def: "Posterior region of the developing endomesoderm." [XAO:MEF] +is_a: XAO:0003186 ! anatomical region +relationship: develops_from XAO:0003044 ! endomesoderm +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0003044 ! endomesoderm +relationship: start_stage XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:0005308 +name: atrioventricular valve +def: "A cardial valve in the atrioventricular region that separates the atrium from the ventricle and prevents backflow from the ventricles into the atria during systole." [UBERON:0002133] +xref: UBERON:0002133 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000064 ! heart +relationship: start_stage XAO:1000054 ! NF stage 42 + +[Term] +id: XAO:0005309 +name: cephalic nerve +def: "A nerve that is part of the head." [UBERON:0011779] +synonym: "head nerve" RELATED [] +synonym: "nerve of head region" RELATED [] +xref: UBERON:0011779 +is_a: XAO:0003047 ! nerve +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000178 ! peripheral nervous system +relationship: part_of XAO:0003024 ! head +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005311 +name: myofibril +def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [GO:0030016] +synonym: "striated muscle fibre" RELATED [] +xref: GO:0030016 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000174 ! skeletal muscle +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005312 +name: M band +def: "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." [GO:0031430] +synonym: "M line" NARROW [] +synonym: "mesophragma" RELATED [] +xref: GO:0031430 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005284 ! sarcomere +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005313 +name: actin cytoskeleton +def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GO:0015629] +xref: GO:0015629 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005314 +name: prootic bone +def: "Either of the paired endochondral bones forming the anterior and lateral walls of the otic capsules." [UBERON:0004746] +xref: UBERON:0004746 +is_a: XAO:0004018 ! endochondral bone +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005225 ! otic capsule +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0005315 +name: retinal vein +def: "Vein that is part of the periocular region." [XAO:EJS] +is_a: XAO:0000115 ! vein +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004089 ! periocular region +relationship: start_stage XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:0005316 +name: periocular mesenchyme +def: "Head mesenchyme that is part of the periocular region." [XAO:EJS] +synonym: "POM" EXACT [] +synonym: "ventronasal periocular mesenchyme" RELATED [] +is_a: XAO:0004307 ! head mesenchyme +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: part_of XAO:0004089 ! periocular region +relationship: start_stage XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:0005317 +name: neuron projection +def: "A prolongation or process extending from a nerve cell." [GO:0043005] +synonym: "nerve fiber" RELATED [] +synonym: "neurite" NARROW [] +synonym: "neuron process" EXACT [] +synonym: "neuron protrusion" EXACT [] +synonym: "neuronal cell projection" EXACT [] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003023 ! neuron +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005318 +name: cortical actin cytoskeleton +def: "The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane." [GO:0030864] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005313 ! actin cytoskeleton +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005319 +name: actin filament +def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells." [GO:0005884] +synonym: "microfilament" EXACT [] +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005313 ! actin cytoskeleton +relationship: start_stage XAO:1000083 ! oocyte stage I + +[Term] +id: XAO:0005320 +name: roof of mouth +def: "A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity." [UBERON:0007375] +synonym: "palate" RELATED [] +synonym: "palatum" RELATED [] +synonym: "primary palate" RELATED [] +xref: UBERON:0007375 +is_a: XAO:0003037 ! multi-tissue structure +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003029 ! mouth +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:0005321 +name: intercanthal region +def: "Region of the face between the two inner (medial) canthi of the eye." [XAO:MEF] +synonym: "inter-canthal line" RELATED [] +is_a: XAO:0003186 ! anatomical region +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0004024 ! craniofacial region +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005322 +name: tadpole +def: "An organism at the tadpole stage." [UBERON:0002547] +xref: UBERON:0002547 +is_a: XAO:0003004 ! whole organism +relationship: end_stage XAO:1000078 ! NF stage 66 +relationship: start_stage XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:0005323 +name: lymphoblast +def: "An immature cell which typically differentiates to form a mature lymphocyte." [XAO:curators] +is_a: XAO:0003012 ! cell +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0003152 ! immune system +relationship: start_stage XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:0005324 +name: anterior lateral line ganglion +def: "Ganglion that develops from a cranial ectodermal placode and contains sensory neurons that innervate the anterior lateral line system." [XAO:EJS] +synonym: "anterior lateral line ganglia" RELATED PLURAL [] +is_a: XAO:0004457 ! lateral line ganglion +relationship: develops_from XAO:0004221 ! anterior lateral line placode +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:0005325 +name: syndetome +def: "Subdomain that occupies the dorso-lateral portion of a somite and comprises tendon progenitor cells. It is located between the neighboring sclerotome and myotome, at the future site of connection between bone and muscle, and gives rise to the axial tendons of the body." [https://discovery.lifemapsc.com/in-vivo-development/somite/syndetome] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000397 ! sclerotome +relationship: end_stage XAO:1000059 ! NF stage 47 +relationship: part_of XAO:0000058 ! somite +relationship: start_stage XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:0005326 +name: axon microtubule bundle +def: "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment." [GO:1901589] +synonym: "axon microtubule fascicle" EXACT [] +synonym: "microtubule bundle of axon" EXACT [] +synonym: "microtubule fascicle of axon" EXACT [] +xref: GO:1901589 +is_a: XAO:0004290 ! cell part +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0005015 ! axon +relationship: start_stage XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:0005327 +name: chordal neural crest +def: "Neural crest comprising sacral, vagal, and trunk neural crest." [XAO:curators] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0000001 ! ectoderm +relationship: end_stage XAO:1000046 ! NF stage 31 +relationship: part_of XAO:0000048 ! neural crest +relationship: start_stage XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:0005422 +name: septum +def: "A wall, dividing a cavity or structure into smaller ones." [UBERON:0003037] +synonym: "septa" RELATED PLURAL [] +xref: UBERON:0003037 +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: start_stage XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:0005423 +name: anterior notochord +def: "The anterior portion of the notochord." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0005424 +name: posterior notochord +def: "The posterior portion of the notochord." [XAO:EJS] +is_a: XAO:0003040 ! tissue +relationship: end_stage XAO:0000437 ! death +relationship: part_of XAO:0000055 ! notochord +relationship: start_stage XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:0005425 +name: transient tracheoesophageal septum +def: "Temporary septum formed from epithelial tissue dividing the esophagus from the trachea. After mesenchymal invasion this gives rise to the permanent tissue separating the esophagus from the trachea." [XAO:MEF] +synonym: "esophagotracheal septum" RELATED [] +synonym: "tracheoesophageal septum" RELATED [] +synonym: "transient TES" EXACT [] +is_a: XAO:0005422 ! septum +relationship: develops_from XAO:0005426 ! tracheoesophageal fold +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0000118 ! trachea +relationship: part_of XAO:0000127 ! esophagus +relationship: part_of XAO:0005127 ! anterior foregut +relationship: start_stage XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:0005426 +name: tracheoesophageal fold +def: "Any of the longitudinal folds in the respiratory diverticulum that fuse to form the tracheoesophageal septum, which separates the esophagus from the trachea." [XAO:MEF] +synonym: "tracheoesophageal crest" RELATED [] +synonym: "tracheoesophageal folds" RELATED PLURAL [] +synonym: "tracheoesophageal ridge" RELATED [] +is_a: XAO:0003040 ! tissue +relationship: develops_from XAO:0005127 ! anterior foregut +relationship: end_stage XAO:1000056 ! NF stage 44 +relationship: part_of XAO:0005127 ! anterior foregut +relationship: start_stage XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:1000000 +name: Xenopus developmental stage +namespace: xenopus_developmental_stage +def: "A temporal interval that defines Xenopus life from unfertilized egg to adult and death stages." [XAO:EJS] + +[Term] +id: XAO:1000001 +name: NF stage 1 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 1, corresponding to an embryo of age 0 hr and having the following external morphological criteria: One cell stage, shortly after fertilization. Pigmentation darker ventrally than dorsally. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "zygote" RELATED [] +xref: UBERON:0000106 +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000012 ! embryonic stage + +[Term] +id: XAO:1000002 +name: early tailbud stage +namespace: xenopus_developmental_stage +def: "Tailbud stage that refers to the earlier events associated with this stage, comprising Nieuwkoop and Faber stages 22 to 28." [Bgee:curator, ISBN:0815318960] +synonym: "early tailbud" EXACT [] +is_a: XAO:1000007 ! tailbud stage + +[Term] +id: XAO:1000003 +name: blastula stage +namespace: xenopus_developmental_stage +def: "Embryonic stage during which the solid morula acquires an internal cavity, comprising Nieuwkoop and Faber stages 7 to 9." [ISBN:0471209627, ISBN:0815318960] +synonym: "blastula" EXACT [] +xref: UBERON:0000108 +is_a: XAO:1000012 ! embryonic stage +relationship: preceded_by XAO:1000004 ! cleavage stage + +[Term] +id: XAO:1000004 +name: cleavage stage +namespace: xenopus_developmental_stage +def: "Embryonic stage during which the zygote undergoes synchronous divisions into 2, 4, 8, 16, etc. blastomeres, comprising Nieuwkoop and Faber stages 2 to 6.5." [ISBN:0471209627, ISBN:0815318960] +synonym: "cleavage" EXACT [] +xref: UBERON:0000107 +is_a: XAO:1000012 ! embryonic stage + +[Term] +id: XAO:1000005 +name: gastrula stage +namespace: xenopus_developmental_stage +def: "Embryonic stage during which gastrulation takes place, with a proportion of cells migrating below the surface of the embryo to form two inner layers (endoderm and mesoderm) and the cells which remain outside spreading over the whole surface of the embryo to form the ectoderm; comprising Nieuwkoop and Faber stages 10 to 12.5." [ISBN:0471209627, ISBN:0815318960] +synonym: "gastrula" EXACT [] +xref: UBERON:0000109 +is_a: XAO:1000012 ! embryonic stage +relationship: preceded_by XAO:1000003 ! blastula stage + +[Term] +id: XAO:1000006 +name: neurula stage +namespace: xenopus_developmental_stage +def: "Embryonic stage during which the future nervous system appears as a thickened plate in dorsal ectoderm, the plate then rolling up at its sides to form a tube; comprising Nieuwkoop and Faber stages 13 to 21." [ISBN:0471209627, ISBN:0815318960] +synonym: "neurula" EXACT [] +xref: UBERON:0000110 +is_a: XAO:1000012 ! embryonic stage +relationship: preceded_by XAO:1000005 ! gastrula stage + +[Term] +id: XAO:1000007 +name: tailbud stage +namespace: xenopus_developmental_stage +def: "Embryonic stage during which neurulation is completed and tail formation begins, visible by an emerging tail primordium; comprising Nieuwkoop and Faber stages 22 to 44 (feeding), including the beginning of hatching (NF stage 35/36)." [http://www.nature.com/nrg/journal/v5/n6/glossary/nrg1347.html, ISBN:0815318960] +xref: UBERON:0009741 +is_a: XAO:1000012 ! embryonic stage +relationship: preceded_by XAO:1000006 ! neurula stage + +[Term] +id: XAO:1000008 +name: tadpole stage +namespace: xenopus_developmental_stage +def: "The post-embryonic Xenopus developmental stage from feeding to the end of metamorphosis, encompassing Weisz's first-form tadpole (equivalent to Nieuwkoop and Faber 45 to 49), second-form tadpole (NF 49 to 56) and third-form tadpole (NF 56 to 60-plus) stages." [ISBN:0471209627, ISSN:0003-276X] +synonym: "larva" RELATED [] +synonym: "larval stage" RELATED [] +synonym: "tadpole" EXACT [] +xref: UBERON:0009849 +is_a: XAO:1000095 ! post-embryonic stage +relationship: preceded_by XAO:1000007 ! tailbud stage + +[Term] +id: XAO:1000009 +name: obsolete frog +namespace: xenopus_developmental_stage +is_obsolete: true +replaced_by: XAO:1000093 + +[Term] +id: XAO:1000010 +name: juvenile frog stage +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that corresponds to a sexually immature post-tadpole animal." [XAO:EJS] +synonym: "juvenile frog" EXACT [] +xref: UBERON:0000112 +is_a: XAO:1000095 ! post-embryonic stage +relationship: preceded_by XAO:1000008 ! tadpole stage + +[Term] +id: XAO:1000011 +name: NF stage 2 (2-cell) +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 2, corresponding to an embryo of age 1 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Advanced two cell stage. First cleavage groove has reached vegetal pole. Ventral side of blastomeres darker than dorsal side. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "2-cell stage" EXACT [] +xref: UBERON:0007232 +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000028 ! NF stage 2- + +[Term] +id: XAO:1000012 +name: embryonic stage +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that starts with fertilization and ends with the formed feeding larva." [Bgee:curator, XAO:EJS] +xref: UBERON:0000068 +is_a: XAO:1000000 ! Xenopus developmental stage +relationship: preceded_by XAO:1000082 ! unfertilized egg stage + +[Term] +id: XAO:1000013 +name: NF stage 3 (4-cell) +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 3, corresponding to an embryo of age 2 hr at 22-24 Celsius and having the following external morphological criteria: Advanced four-cell stage. Second cleavage groove has reached vegetal pole. In animal view dorsal blastomeres usually smaller than ventral ones; the latter darker than the former. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "4-cell stage" EXACT [] +xref: UBERON:0007233 +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000011 ! NF stage 2 (2-cell) + +[Term] +id: XAO:1000014 +name: NF stage 4 (8-cell) +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 4, corresponding to an embryo of age 2 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Advanced eight cell stage. Dorsal micro- and macromeres usually smaller than ventral ones; dorsal micromeres less pigmented than ventral ones. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "8-cell stage" EXACT [] +xref: UBERON:0007236 +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000013 ! NF stage 3 (4-cell) + +[Term] +id: XAO:1000015 +name: NF stage 5 (16-cell) +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 5, corresponding to an embryo of age 2 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Advanced sixteen cell stage. Dorsal micromeres distinctly smaller and less pigmented than ventral ones. Macromeres entirely separated by cleavage grooves. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "16-cell stage" EXACT [] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000014 ! NF stage 4 (8-cell) + +[Term] +id: XAO:1000016 +name: NF stage 6 (32-cell) +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 6, corresponding to an embryo of age 3 hr at 22-24 Celsius and having the following external morphological criteria: Advanced thirty-two cell stage. Distinction between dorsal and ventral micromeres as in preceding stage. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "32-cell stage" EXACT [] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000015 ! NF stage 5 (16-cell) + +[Term] +id: XAO:1000017 +name: NF stage 7 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 7 (64-cell stage), corresponding to an embryo of age 4 hr at 22-24 Celsius and having the following external morphological criteria: Large-cell blastula stage. In animal view about 10 micromeres along meridian. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "64-cell stage" EXACT [] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000003 ! blastula stage +relationship: preceded_by XAO:1000029 ! NF stage 6.5 + +[Term] +id: XAO:1000018 +name: NF stage 8 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 8 (128-cell stage), corresponding to an embryo of age 5 hr at 22-24 Celsius and having the following external morphological criteria: Medium-cell blastula stage. Surface not yet entirely smooth. Border of animal pigment cap more diffuse at dorsal than at lateral and ventral sides. Gradual transition in cell size from animal to vegetative pole. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "128-cell stage" EXACT [] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000003 ! blastula stage +relationship: preceded_by XAO:1000017 ! NF stage 7 + +[Term] +id: XAO:1000019 +name: NF stage 9 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 9, corresponding to an embryo of age 7 hr at 22-24 Celsius and having the following external morphological criteria: Fine-cell blastula stage. Animal cells smaller at dorsal than at ventral side. Border between marginal zone and vegetative field distinct, particularly dorsally, owing to difference in cell size. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000003 ! blastula stage +relationship: preceded_by XAO:1000018 ! NF stage 8 + +[Term] +id: XAO:1000020 +name: NF stage 10 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 10, corresponding to an embryo of age 9 hr at 22-24 Celsius and having the following external morphological criteria: Initial gastrula stage. First indication of blastopore only by pigment concentration. No formation of groove. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000019 ! NF stage 9 + +[Term] +id: XAO:1000021 +name: NF stage 11 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 11, corresponding to an embryo of age 11 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Horse-shoe-shaped blastopore stage. Blastopore groove surrounding about half of future yolk plug and indicated at its ventral side; future yolk plug often rounded rectangular, slightly elongated in dorso-ventral direction, diameter more than two-fifths of diameter of egg (plus or minus 50 degrees of circumference). Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000031 ! NF stage 10.5 + +[Term] +id: XAO:1000022 +name: NF stage 12 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 12, corresponding to an embryo of age 13 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Medium yolk plug stage. Yolk plug circular; diameter somewhat less than one fourth of diameter of egg (plus or minus 25 degrees). More and less pigmented fields radiating from yolk plug. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000032 ! NF stage 11.5 + +[Term] +id: XAO:1000023 +name: NF stage 13 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 13, corresponding to an embryo of age 14 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Slit-blastopore stage. Neural plate faintly delimited; slight elevation of its rostral part and slight flattening of its caudal part. Caudal part of median groove formed. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000033 ! NF stage 12.5 + +[Term] +id: XAO:1000024 +name: NF stage 14 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 14, corresponding to an embryo of age 16 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Neural plate stage. Cerebral part of neural plate bent downwards, with median elevation at rostral end of median groove. Initial elevation of neural folds, most pronounced in future nucal region. Blastopore always slit-shaped. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000023 ! NF stage 13 + +[Term] +id: XAO:1000025 +name: NF stage 15 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 15, corresponding to an embryo of age 17 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Early neural fold stage. Presumptive cement gland faintly circumscribed. Anterior part of neural plate roundish. Neural folds distinct, except medio-rostrally; initial formation of sharp inner ridges on neural folds in rhombencephalic region. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000024 ! NF stage 14 + +[Term] +id: XAO:1000026 +name: NF stage 16 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 16, corresponding to an embryo of age 18 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Mid neural fold stage. Anterior part of neural plate rectangular; darkly pigmented eye anlagen present; neural plate sharply constricted in the middle. Inner ridges on neural folds forming angle of about 90 degrees with neural plate in rhombencephalic region. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000025 ! NF stage 15 + +[Term] +id: XAO:1000027 +name: NF stage 17 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 17, corresponding to an embryo of age 18 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Late neural fold stage. Anterior part of neural plate oblong triangular, angles formed by eye anlagen. Neural folds approaching each other from blastopore up to anterior trunk region. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000026 ! NF stage 16 + +[Term] +id: XAO:1000028 +name: NF stage 2- +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 2-, corresponding to an embryo of age 1 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Beginning of first cleavage. First cleavage groove has not yet reached vegetal pole. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000001 ! NF stage 1 + +[Term] +id: XAO:1000029 +name: NF stage 6.5 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 6.5, corresponding to an embryo of age 3 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Morula stage. About 48 blastomeres. In animal view about 6 micromeres along meridian. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "morula" RELATED [ISBN:0815318960] +xref: UBERON:0000085 +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000004 ! cleavage stage +relationship: preceded_by XAO:1000016 ! NF stage 6 (32-cell) + +[Term] +id: XAO:1000030 +name: NF stage 10.25 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 10.25, corresponding to an embryo of age 10 hr at 22-24 Celsius and having the following external morphological criteria: Early gastrula stage. First formation of dorsal blastopore groove; the groove is still straight. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +synonym: "NF stage 10+" EXACT [] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000020 ! NF stage 10 + +[Term] +id: XAO:1000031 +name: NF stage 10.5 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 10.5, corresponding to an embryo of age 11 hr at 22-24 Celsius and having the following external morphological criteria: Crescent-shaped blastopore stage. Blastopore groove angular. Vegetal field slightly decreased in size, ventral border of future yolk plug indicated by pigment contraction. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000030 ! NF stage 10.25 + +[Term] +id: XAO:1000032 +name: NF stage 11.5 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 11.5, corresponding to an embryo of age 12 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Large yolk plug stage. Blastopore groove closed ventrally; yolk plug not yet quite circular. At ventral side concentrated superficial pigment still visible. Diameter of yolk plug about a third of diameter of egg (plus or minus 40 degrees). Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000021 ! NF stage 11 + +[Term] +id: XAO:1000033 +name: NF stage 12.5 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 12.5, corresponding to an embryo of age 14 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Small yolk plug stage. Future position of neural plate and median groove indicated by darker pigment lines. Yolk plug usually ovoid, variable in size. Length: 1.4 - 1.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000005 ! gastrula stage +relationship: preceded_by XAO:1000022 ! NF stage 12 + +[Term] +id: XAO:1000034 +name: NF stage 18 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 18, corresponding to an embryo of age 19 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Neural groove stage. Anterior part of neural plate narrow, more or less club-shaped, often narrower towards rostral end. Parallel neural folds in trunk region very close to each other, not yet touching. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000027 ! NF stage 17 + +[Term] +id: XAO:1000035 +name: NF stage 19 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 19, corresponding to an embryo of age 20 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Initial neural tube stage. Neural folds touching each other, except for inconstant openings at anterior and posterior end and behind nucal region. Considerable lateral extension of brain. Lateral outline of embryo still convex. Length: 1.5 - 1.6 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000034 ! NF stage 18 + +[Term] +id: XAO:1000036 +name: NF stage 20 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 20, corresponding to an embryo of age 21 hr 45 min at 22-24 Celsius and having the following external morphological criteria: Neural folds fused, suture still present. The two eye anlagen showing through dumb-bell-shaped, eyes hardly protruding. Beginning of stretching of embryos. Lateral outline flat. Length: 1.7 - 1.8 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000035 ! NF stage 19 + +[Term] +id: XAO:1000037 +name: NF stage 21 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 21, corresponding to an embryo of age 22 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Suture of neural tube completely closed. Delimitation of frontal field by pigment lines. Primary eye vesicles showing through in the form of two separate, obliquely placed oval spots; beginning of protrusion of eyes. Lateral outline of embryo just becoming concave, ventral outline flat. Length: 1.9 - 2.0 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000006 ! neurula stage +relationship: preceded_by XAO:1000036 ! NF stage 20 + +[Term] +id: XAO:1000038 +name: NF stage 22 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 22, corresponding to an embryo of age 24 hr at 22-24 Celsius and having the following external morphological criteria: Distinct protrusion of eyes. Initial groove between jaw- and gill-areas only at latero-dorsal side. Lateral and ventral outlines of embryo slightly concave. Anal opening displaced to ventral side. Vitelline membrane becoming wider. Length: 2.0 - 2.2 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000037 ! NF stage 21 + +[Term] +id: XAO:1000039 +name: NF stage 23 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 23, corresponding to an embryo of age 1 day, 45 min at 22-24 Celsius and having the following external morphological criteria: Jaw- and gill-areas completely separated by groove. Ventral outline of embryo more concave. Length: 2.2 - 2.4 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000038 ! NF stage 22 + +[Term] +id: XAO:1000040 +name: NF stage 24 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 24, corresponding to an embryo of age 1 day, 2 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Eyes protruding less far laterally than gill-area. Gill-area more prominent than jaw-area, gill-area not yet grooved. Ventral outline of embryo nicked. Tail bud discernible. Initial motor reactions to external stimulation. Length: 2.5 - 2.7 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000039 ! NF stage 23 + +[Term] +id: XAO:1000041 +name: NF stage 25 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 25, corresponding to an embryo of age 1 day, 3 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Eyes protruding equally far or further laterally than gill-area. Gill-area grooved. Invagination of otic vesicle indicated by pigment spot. Beginning of fin formation. Length: 2.8 - 3.0 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000040 ! NF stage 24 + +[Term] +id: XAO:1000042 +name: NF stage 26 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 26, corresponding to an embryo of age 1 day, 5 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Otic vesicle protruding. Pronephros distinctly visible. Myotomes showing through for the first time. Fin somewhat broadened at dorso-caudal end of body. Beginning of spontaneous movements. Length: 3.0 - 3.3 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000041 ! NF stage 25 + +[Term] +id: XAO:1000043 +name: NF stage 27 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 27, corresponding to an embryo of age 1 day, 7 hr 15 min at 22-24 Celsius and having the following external morphological criteria: Lateral flattening of eyes. Fin transluscent, except for region behind anus. Tail bud formation accentuated in lateral outline. Length: 3.4 - 3.7 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000042 ! NF stage 26 + +[Term] +id: XAO:1000044 +name: NF stage 28 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 28, corresponding to an embryo of age 1 day, 8 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Fin extending up to anus. Fin broadened and distinctly divided into outer transparent and inner translucent band. Length: 3.8 - 4.0 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000002 ! early tailbud stage +relationship: preceded_by XAO:1000043 ! NF stage 27 + +[Term] +id: XAO:1000045 +name: NF stage 29 and 30 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 29/30, corresponding to an embryo of age 1 day, 11 hr at 22-24 Celsius and having the following external morphological criteria: Gray eye cup showing through for the first time. Fin transparent up to the base over its whole length. Tail bud distinct. Length: 4.0 - 4.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000044 ! NF stage 28 + +[Term] +id: XAO:1000046 +name: NF stage 31 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 31, corresponding to an embryo of age 1 day, 13 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Tail bud equally long as broad. Length: 4.2 - 4.8 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000045 ! NF stage 29 and 30 + +[Term] +id: XAO:1000047 +name: NF stage 32 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 32, corresponding to an embryo of age 1 day, 16 hr at 22-24 Celsius and having the following external morphological criteria: Eye cup horse-shoe-shaped, standing out distinctly. Length of tail bud about 1.5 times its breadth. Length: 4.5 - 5.1 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000046 ! NF stage 31 + +[Term] +id: XAO:1000048 +name: NF stage 33 and 34 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 33/34, corresponding to an embryo of age 1 day, 20 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Stomodeal invagination a shallow vertical groove. Dorsal part of eye more pigmented than ventral part; distinct melanophores in dorsal part. Melanophores appearing dorsally on the head and laterally in a row extending from just below the pronephros backwards. Length of tail bud about twice its breadth. Beginning of heart beat. Length: 4.7 - 5.3 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000047 ! NF stage 32 + +[Term] +id: XAO:1000049 +name: NF stage 35 and 36 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 35/36, corresponding to an embryo of age 2 days, 2 hr at 22-24 Celsius and having the following external morphological criteria: Stomodeal invagination roundish. Eye entirely black, choroid fissure nearly closed. Formation of two gill rudiments, anterior one nipple-shaped. Melanophores appearing on back. Posterior outline of proctodeum still curved. Length of tail bud about three times its breadth. Beginning of hatching. Length: 5.3 - 6.0 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000048 ! NF stage 33 and 34 + +[Term] +id: XAO:1000050 +name: NF stage 37 and 38 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 37/38, corresponding to an embryo of age 2 days, 5 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Stomodeal invagination much deeper, opening round. Both gill rudiments nipple-shaped, a branch of the anterior one indicated. Posterior outline of proctodeum straight, forming very obtuse angle with ventral border of tail myotomes. Melanophores spreading over tail. Length: 5.6 - 6.2 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000049 ! NF stage 35 and 36 + +[Term] +id: XAO:1000051 +name: NF stage 39 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 39, corresponding to an embryo of age 2 days, 8 hr 30 min at 22-24 Celsius and having the following external morphological criteria: Melanophores appearing around nasal pits. Opening of stomodeal invagination transversely elongated. Melanophores on back arranged in a superficial and a deeper layer. Outlines of proctodeum and tail myotomes forming angle of about 135 degrees. Melanophores appearing along ventral edge of tail musculature. Length: 5.9 - 6.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000050 ! NF stage 37 and 38 + +[Term] +id: XAO:1000052 +name: NF stage 40 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 40, corresponding to an embryo of age 2 days, 18 hr at 22-24 Celsius and having the following external morphological criteria: Mouth broken through. Length of gills about twice their breadth, posterior one sometimes also showing a branch. Outlines of proctodeum and tail myotomes forming angles of 90 degrees. Beginning of blood circulation in gills. Length: 6.3 - 6.8 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000051 ! NF stage 39 + +[Term] +id: XAO:1000053 +name: NF stage 41 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 41, corresponding to an embryo of age 3 days, 4 hr at 22-24 Celsius and having the following external morphological criteria: Gills broader and flatter, more laterally directed. Formation of a left-rostral and a right-caudal furrow in yolk mass; torsion of interjacent part about 45 degrees; formation of conical proctodeum, forming angle of about 60 degrees with tail myotomes. Formation of fin rostral to proctodeum; ventral outline of yolk mass and proctodeum a smooth concave line. Length: 6.7 - 7.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000052 ! NF stage 40 + +[Term] +id: XAO:1000054 +name: NF stage 42 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 42, corresponding to an embryo of age 3 days, 8 hr at 22-24 Celsius and having the following external morphological criteria: Beginning of formation of opercular folds. Torsion of intestine about 90 degrees; proctodeum connected with yolk mass by short horizontal intestinal tube. Length: 7.0 - 7.7 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000053 ! NF stage 41 + +[Term] +id: XAO:1000055 +name: NF stage 43 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 43, corresponding to an embryo of age 3 days, 15 hr at 22-24 Celsius and having the following external morphological criteria: Lateral line system becoming visible externally. Cement gland losing its pigment. Torsion of intestine about 180 degrees; proctodeum narrower, arched or S-shaped. Length: 7.5 - 8.3 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000054 ! NF stage 42 + +[Term] +id: XAO:1000056 +name: NF stage 44 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 44, corresponding to an embryo of age 3 days, 20 hr at 22-24 Celsius and having the following external morphological criteria: Appearance of tentacle rudiments. Opercular folds protruding further. Coiling part of intestine showing S-shaped loop; torsion about 360 degrees. Blood-circulation in gills usually ceased (gills smaller). Length: 7.8 - 8.5 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000080 ! late tailbud stage +relationship: preceded_by XAO:1000055 ! NF stage 43 + +[Term] +id: XAO:1000057 +name: NF stage 45 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 45, corresponding to a tadpole of age 4 days, 2 hr at 22-24 Celsius and having the following external morphological criteria: Operculum partly covering gills, edge still straight. Intestine spiralized in ventral aspects, showing 1.5 revolutions. Beginning of feeding. Length: 8 - 10 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000056 ! NF stage 44 + +[Term] +id: XAO:1000058 +name: NF stage 46 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 46, corresponding to a tadpole of age 4 days, 10 hr at 22-24 Celsius and having the following external morphological criteria: Edge of operculum becoming convex. Xantophores appearing on eye and abdomen. Intestine showing 2 to 2.5 revolutions. Hindlimb bud visible for the first time. Length: 9 - 12 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000057 ! NF stage 45 + +[Term] +id: XAO:1000059 +name: NF stage 47 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 47, corresponding to a tadpole of age 5 days, 12 hr at 22-24 Celsius and having the following external morphological criteria: Tentacles larger. Edge of operculum forming quarter of a circle. Xantophores forming opaque layer on abdomen. Intestine showing 2.5 to 3.5 revolutions. Hindlimb bud more distinct. Length: 12 - 15 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000058 ! NF stage 46 + +[Term] +id: XAO:1000060 +name: NF stage 48 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 48, corresponding to a tadpole of age 7.5 days at 22-24 Celsius and having the following external morphological criteria: Beginning of pigmentation around n. acusticus. Forelimb bud visible for the first time. Shining gold-coloured abdomen. Hindlimb bud semicircular in lateral aspect. Length: 14 - 17 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000059 ! NF stage 47 + +[Term] +id: XAO:1000061 +name: NF stage 49 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 49, corresponding to a tadpole of age about 12 days at 22-24 Celsius and having the following external morphological criteria: Melanophores usually appearing around thymus gland and nerves and blood vessels of head; xantophores appearing on pericard. Forelimb bud distinct. Hindlimb bud somewhat longer, distal outline still circular, no constrictions at base. Melanophores appearing on dorsal and ventral fin. Length: 17 - 23 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000060 ! NF stage 48 + +[Term] +id: XAO:1000062 +name: NF stage 50 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 50, corresponding to a tadpole of age about 15 days at 22-24 Celsius and having the following external morphological criteria: Forelimb bud somewhat oval-shaped in dorsal aspect. Hindlimb bud longer than broad, constricted at base, distal outline somewhat conical. Length: 20 - 27 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000061 ! NF stage 49 + +[Term] +id: XAO:1000063 +name: NF stage 51 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 51, corresponding to a tadpole of age about 17 days at 22-24 Celsius and having the following external morphological criteria: Tentacles much longer. Forelimb bud oval-shaped in lateral aspect. Hindlimb bud conical in shape, its length about 1.5 times its breadth; melanophores appearing on it. Length: 28 - 36 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000062 ! NF stage 50 + +[Term] +id: XAO:1000064 +name: NF stage 52 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 52, corresponding to a tadpole of age about 21 days at 22-24 Celsius and having the following external morphological criteria: Forelimb bud irregularly conical. Hindlimb bud showing first indication of ankle constriction and first sign of flattening of foot. Length: 42 - 56 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000063 ! NF stage 51 + +[Term] +id: XAO:1000065 +name: NF stage 53 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 53, corresponding to a tadpole of age about 24 days at 22-24 Celsius and having the following external morphological criteria: Fore- and hindlimbs in paddle stage. Hindlimb whithout foot somewhat longer than broad; 4th and 5th toe indicated. Length: 50 - 60 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000064 ! NF stage 52 + +[Term] +id: XAO:1000066 +name: NF stage 54 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 54, corresponding to a tadpole of age about 26 days at 22-24 Celsius and having the following external morphological criteria: All four fingers indicated; edge of hand slightly scalloped between fingers; melanophores appearing on forelimb. Length of hindlimb without foot nearly twice its breadth; all five toes indicated, the second only very slightly. Length: 58 - 65 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000089 ! premetamorphosis stage +relationship: preceded_by XAO:1000065 ! NF stage 53 + +[Term] +id: XAO:1000067 +name: NF stage 55 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 55, corresponding to a tadpole of age about 32 days at 22-24 Celsius and having the following external morphological criteria: Hand pronated about 90 degrees; free parts of fingers about equally long as broad. Length of hindlimb without foot about 3 times its breadth; length of cartilages of 4th and 5th toe about 4 times their breadth. Length: 70 - 80 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000090 ! prometamorphosis stage +relationship: preceded_by XAO:1000066 ! NF stage 54 + +[Term] +id: XAO:1000068 +name: NF stage 56 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 56, corresponding to a tadpole of age about 38 days at 22-24 Celsius and having the following external morphological criteria: Elbow and wrist clearly indicated; length of free parts of fingers 3 to 4 times their breadth. Length of cartilages of 4th and 5th toe about 6 times their breadth. Length: 70 - 100 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000090 ! prometamorphosis stage +relationship: preceded_by XAO:1000067 ! NF stage 55 + +[Term] +id: XAO:1000069 +name: NF stage 57 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 57, corresponding to a tadpole of age about 41 days at 22-24 Celsius and having the following external morphological criteria: Pigment-free spot appearing above \"Stirnorgan\". Angle of elbow more than 90 degrees; fingers stretched out in forelimb atrium, their length about 7 times their breadth. Length: 75 - 105 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000090 ! prometamorphosis stage +relationship: preceded_by XAO:1000068 ! NF stage 56 + +[Term] +id: XAO:1000070 +name: NF stage 58 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 58, corresponding to a tadpole of age about 44 days at 22-24 Celsius and having the following external morphological criteria: Forelimbs broken through. Guanophores appearing on abdomen and thighs (adult skin areas). All three claws present on hindlimbs. Length: 80 - 110 mm." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000069 ! NF stage 57 + +[Term] +id: XAO:1000071 +name: NF stage 59 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 59, corresponding to a tadpole of age about 45 days at 22-24 Celsius and having the following external morphological criteria: Tentacles beginning to shrivel up. Stretched forelimb reaching down to base of hindlimb. Guanophores appearing near base of forelimb (adult skin area); anterior border of adult skin area on abdomen not yet sharp; appearance of irregular dark spots on back." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000070 ! NF stage 58 + +[Term] +id: XAO:1000072 +name: NF stage 60 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 60, corresponding to a tadpole of age about 46 days at 22-24 Celsius and having the following external morphological criteria: N. olfactorius still longer than bulbus olfactorius. Guanophores appearing on lower jaw (adult skin area). Openings of gill chambers still wide. Distal half of fingers of stretched forelimb extending beyond base of hindlimb; forelimb still situated behind level of heart. Adult skin area of base of forelimb covered with guanophores; anterior border of adult skin area on abdomen sharper, reaching up to heart." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000071 ! NF stage 59 + +[Term] +id: XAO:1000073 +name: NF stage 61 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 61, corresponding to a tadpole of age about 48 days at 22-24 Celsius and having the following external morphological criteria: Head narrower. Tentacles considerably shortened, mostly curved backwards. Length of n. olfactorius equal to diameter of bulbus olfactorius. 4th arterial arch seen just in front of adult skin area of forelimb. Openings of gill chambers considerably narrowed. Forelimb at level of posterior half of heart. Adult skin area on abdomen covering posterior half of heart. Fins considerably reduced." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000072 ! NF stage 60 + +[Term] +id: XAO:1000074 +name: NF stage 62 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 62, corresponding to a tadpole of age about 49 days at 22-24 Celsius and having the following external morphological criteria: Head still somewhat broader than cranial part of trunk. Tentacles short, straight. N. olfactorius shorter than diameter of bulbus olfactorius. Corner of mouth still in front of eye. Thymus gland somewhat protruding. 3rd arterial arch (\"larval aorta\") seen at distance of its own diameter in front of adult skin area of forelimb. Opening of operculum reduced to curved slit. Forelimb at level of middle of heart. Anterior border of adult skin area on abdomen entirely sharp, mostly nicked medially. Ventral fin disappeared from abdomen." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000073 ! NF stage 61 + +[Term] +id: XAO:1000075 +name: NF stage 63 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 63, corresponding to a tadpole of age about 51 days at 22-24 Celsius and having the following external morphological criteria: Head narrower than trunk. Tentacles mostly disappeared. Corner of mouth at level of caudal border of eye. \"Larval aorta\" and thymus gland no longer externally visible. Operculum closed. Adult skin areas on abdomen and lower jaw separated by narrow band of larval skin. Forelimb at level of anterior half of heart. Fin mostly perforated near anus. Tail still slightly longer than body." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000074 ! NF stage 62 + +[Term] +id: XAO:1000076 +name: NF stage 64 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 64, corresponding to a tadpole of age about 53 days at 22-24 Celsius and having the following external morphological criteria: Corner of mouth well behind eye. Various adult skin areas joined almost everywhere, borderlines still clearly visible. Length of tail (from anus) is a third of body length." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000075 ! NF stage 63 + +[Term] +id: XAO:1000077 +name: NF stage 65 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 65, corresponding to a tadpole of age about 54 days at 22-24 Celsius and having the following external morphological criteria: Borderlines between adult skin areas partly disappeared. Tail oblong triangular in dorsal aspect, length abouth one tenth of body length." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000076 ! NF stage 64 + +[Term] +id: XAO:1000078 +name: NF stage 66 +namespace: xenopus_developmental_stage +def: "Nieuwkoop and Faber stage 66, corresponding to a tadpole of age about 58 days at 22-24 Celsius and having the following external morphological criteria: Border lines between adult skin areas disappeared. Tail only a very small triangle, no longer visible from ventral side." [ISBN:0815318960] +is_a: XAO:1000094 ! NF stage +relationship: part_of XAO:1000091 ! climax stage +relationship: preceded_by XAO:1000077 ! NF stage 65 + +[Term] +id: XAO:1000079 +name: metamorphosing tadpole stage +namespace: xenopus_developmental_stage +def: "Tadpole stage during which toe differentiation and rapid hindlimb growth continue, followed by tail resorption; comprising Nieuwkoop and Faber stages 54 to 66." [Bgee:curator, ISBN:0815318960] +synonym: "metamorphosing tadpole" EXACT [] +is_a: XAO:1000008 ! tadpole stage +relationship: preceded_by XAO:1000089 ! premetamorphosis stage + +[Term] +id: XAO:1000080 +name: late tailbud stage +namespace: xenopus_developmental_stage +def: "Tailbud stage that refers to the later events associated with this stage, comprising Nieuwkoop and Faber stages 29/30 to 44." [Bgee:curator, ISBN:0815318960] +synonym: "late tailbud" EXACT [] +is_a: XAO:1000007 ! tailbud stage +relationship: preceded_by XAO:1000002 ! early tailbud stage + +[Term] +id: XAO:1000081 +name: unspecified stage +namespace: xenopus_developmental_stage +def: "Unspecified Xenopus developmental stage." [XAO:EJS] +is_a: XAO:1000000 ! Xenopus developmental stage + +[Term] +id: XAO:1000082 +name: unfertilized egg stage +namespace: xenopus_developmental_stage +def: "Any of the stages of the developing or mature Xenopus female gamete." [XAO:EJS] +synonym: "unfertilized egg" EXACT [] +is_a: XAO:1000000 ! Xenopus developmental stage + +[Term] +id: XAO:1000083 +name: oocyte stage I +namespace: xenopus_developmental_stage +def: "The pre-vitellogenic stage of the developing female gamete." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +created_by: lab +creation_date: 2011-09-09T02:23:46Z + +[Term] +id: XAO:1000084 +name: oocyte stage II +namespace: xenopus_developmental_stage +def: "The early vitellogenic stage of the developing female gamete." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000083 ! oocyte stage I +created_by: lab +creation_date: 2011-09-09T02:24:37Z + +[Term] +id: XAO:1000085 +name: oocyte stage III +namespace: xenopus_developmental_stage +def: "The mid-vitellogenic stage of the developing female gamete." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000084 ! oocyte stage II +created_by: lab +creation_date: 2011-09-09T02:24:56Z + +[Term] +id: XAO:1000086 +name: oocyte stage IV +namespace: xenopus_developmental_stage +def: "The stage of the developing female gamete that corresponds to the establishment of polarization along the animal-vegetal axis of the gamete." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000085 ! oocyte stage III +created_by: lab +creation_date: 2011-09-09T02:25:13Z + +[Term] +id: XAO:1000087 +name: oocyte stage V +namespace: xenopus_developmental_stage +def: "The late-vitellogenic stage of the developing female gamete." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000086 ! oocyte stage IV +created_by: lab +creation_date: 2011-09-09T02:25:43Z + +[Term] +id: XAO:1000088 +name: oocyte stage VI +namespace: xenopus_developmental_stage +def: "The developmental stage of the female gamete at which the gamete is fully grown." [XAO:EJS] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000087 ! oocyte stage V +created_by: lab +creation_date: 2011-09-09T02:26:43Z + +[Term] +id: XAO:1000089 +name: premetamorphosis stage +namespace: xenopus_developmental_stage +def: "Tadpole stage during which limb bud growth occurs, comprising Nieuwkoop and Faber stages 45 to 54." [ISBN:0124554032] +synonym: "premetamorphosis" EXACT [] +is_a: XAO:1000008 ! tadpole stage +relationship: preceded_by XAO:1000080 ! late tailbud stage + +[Term] +id: XAO:1000090 +name: prometamorphosis stage +namespace: xenopus_developmental_stage +def: "Metamorphosing tadpole stage during which toe differentiation and rapid hindlimb growth continue, comprising Nieuwkoop and Faber stages 55 to 57." [ISBN:0124554032] +synonym: "prometamorphosis" EXACT [] +is_a: XAO:1000079 ! metamorphosing tadpole stage + +[Term] +id: XAO:1000091 +name: climax stage +namespace: xenopus_developmental_stage +def: "Metamorphosing tadpole stage during which tail resorption occurs, comprising Nieuwkoop and Faber stages 58 to 66." [ISBN:0124554032] +synonym: "climax" EXACT [] +is_a: XAO:1000079 ! metamorphosing tadpole stage +relationship: preceded_by XAO:1000090 ! prometamorphosis stage + +[Term] +id: XAO:1000092 +name: mature egg stage +namespace: xenopus_developmental_stage +def: "The developmental stage of the female gamete at which the gamete has reached maturity." [XAO:EJS] +synonym: "mature egg" RELATED [] +is_a: XAO:1000082 ! unfertilized egg stage +relationship: preceded_by XAO:1000088 ! oocyte stage VI +created_by: lab +creation_date: 2011-09-09T02:32:08Z + +[Term] +id: XAO:1000093 +name: adult frog stage +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that corresponds to a fully formed, mature animal." [XAO:EJS] +synonym: "adult frog" EXACT [] +is_a: XAO:1000095 ! post-embryonic stage +relationship: preceded_by XAO:1000010 ! juvenile frog stage +created_by: lab +creation_date: 2011-09-19T01:53:23Z + +[Term] +id: XAO:1000094 +name: NF stage +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that is one of the 66 standard chronological embryonic and tadpole stages originally described by Nieuwkoop and Faber in the Normal Table of Xenopus laevis (Daudin)." [ISBN:0815318960, XAO:EJS] +synonym: "Nieuwkoop and Faber stage" EXACT [] +synonym: "Nieuwkoop-Faber stage" EXACT [] +is_a: XAO:1000000 ! Xenopus developmental stage +created_by: eriksegerdell +creation_date: 2013-02-09T18:40:27Z + +[Term] +id: XAO:1000095 +name: post-embryonic stage +namespace: xenopus_developmental_stage +def: "Xenopus developmental stage that succeeds the embryonic stage." [XAO:EJS] +xref: UBERON:0000092 +is_a: XAO:1000000 ! Xenopus developmental stage +relationship: preceded_by XAO:1000012 ! embryonic stage + +[Typedef] +id: develops_from +name: develops from +xref: RO:0002202 +is_transitive: true + +[Typedef] +id: end_stage +name: ends during +def: "Anatomical structure/expression stops being viable, obvious or of utility during this developmental stage." [XAO:curators] + +[Typedef] +id: part_of +name: part of +xref: BFO:0000050 +is_transitive: true + +[Typedef] +id: preceded_by +name: preceded by +is_transitive: true + +[Typedef] +id: start_stage +name: starts during +def: "Anatomical structure/expression begins being viable, obvious or of utility during this developmental stage." [XAO:curators] + diff --git a/notebooks/mappings.ipynb b/notebooks/mappings.ipynb new file mode 100644 index 000000000..b211db386 --- /dev/null +++ b/notebooks/mappings.ipynb @@ -0,0 +1,1334 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 1, + "id": "0846c27a", + "metadata": {}, + "outputs": [], + "source": [ + "%reset -f" + ] + }, + { + "cell_type": "markdown", + "id": "70df322b", + "metadata": {}, + "source": [ + "## Import libraries" + ] + }, + { + "cell_type": "code", + "execution_count": 9, + "id": "c94eb15d", + "metadata": {}, + "outputs": [], + "source": [ + "import sys\n", + "import os\n", + "from oaklib.selector import get_resource_from_shorthand\n", + "from oaklib.utilities.mapping.sssom_utils import StreamingSssomWriter\n", + "from oaklib.cli import lexmatch\n", + "from oaklib.utilities.lexical.lexical_indexer import create_lexical_index, lexical_index_to_sssom\n", + "import warnings\n", + "warnings.filterwarnings('ignore')\n" + ] + }, + { + "cell_type": "markdown", + "id": "5f242e47", + "metadata": {}, + "source": [ + "## Declare variables" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "id": "4ff5af2d", + "metadata": {}, + "outputs": [], + "source": [ + "BIOPORTAL=\"bioportal:\"\n", + "OBO=\"obo\"\n", + "# NOTE: Make sure you have your unique biportal api-key in a txt file locally.\n", + "API_KEY_FILE = \"api-key.txt\"\n", + "limb_curie = \"UBERON:0002101\"\n", + "limb_curie_2 = \"MA:0000007\"\n", + "input_dir = \"input\"\n", + "xao_file = \"xao.obo\"\n", + "ma_file = \"ma.obo\"" + ] + }, + { + "cell_type": "markdown", + "id": "38e23328", + "metadata": {}, + "source": [ + "## Functions" + ] + }, + { + "cell_type": "code", + "execution_count": 14, + "id": "34554cd3", + "metadata": {}, + "outputs": [], + "source": [ + "def get_implementation(rsrc:str):\n", + " resource = get_resource_from_shorthand(rsrc)\n", + " oi = resource.implementation_class()\n", + " \n", + " if rsrc == \"bioportal:\":\n", + " oi.load_bioportal_api_key(API_KEY_FILE)\n", + " else:\n", + " resource.directory = input_dir\n", + " oi = resource.implementation_class(resource)\n", + " \n", + " return oi\n", + "\n", + "def render_sssom(rsrc:str, curie:str):\n", + " writer = StreamingSssomWriter(sys.stdout)\n", + " oi = get_implementation(rsrc)\n", + " for m in oi.get_sssom_mappings_by_curie(curie):\n", + " writer.emit(m)\n", + "\n", + " writer.close()\n", + " \n", + "def get_lexmatch(rsrc:str):\n", + " impl = get_implementation(rsrc)\n", + " ix = create_lexical_index(impl)\n", + " msdf = lexical_index_to_sssom(impl, ix)\n", + " return msdf.df\n", + " " + ] + }, + { + "cell_type": "markdown", + "id": "3b8f6a2e", + "metadata": {}, + "source": [ + "# Part 1" + ] + }, + { + "cell_type": "markdown", + "id": "6f8509db", + "metadata": {}, + "source": [ + "## Bioportal => SSSOM" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "id": "dc24affd", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "# curie_map: {}\n", + "# license: UNSPECIFIED\n", + "# mapping_set_id: temp\n", + "subject_id\tpredicate_id\tobject_id\tmatch_type\tmapping_provider\tmapping_tool\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttps://cadsr.nci.nih.gov/metadata/CADSR-VS/4f49aa6124b587b96b0404c5deaa6c0469c62698\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:exactMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tSAME_URI\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:exactMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tSAME_URI\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:exactMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tSAME_URI\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/UBERON_0002101\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttps://cadsr.nci.nih.gov/metadata/CADSR-VS/4516e5ffbeb793c8c61039c695023423951699f5\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttps://cadsr.nci.nih.gov/metadata/CADSR-VS/4516e5ffbeb793c8c61039c695023423951699f5\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + 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"http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.org/obo/owl/FMA#FMA_7182\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/NCIT_C12429\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/NCIT_C12429\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/EHDA_8414\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + 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"http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/NCIT_C12429\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/BTO_0001492\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "http://purl.obolibrary.org/obo/UBERON_0002101\tskos:closeMatch\thttp://purl.obolibrary.org/obo/VHOG_0000336\tUnspecified\thttp://data.bioontology.org/metadata/Mapping\tLOOM\n", + "\n" + ] + } + ], + "source": [ + "render_sssom(BIOPORTAL, limb_curie)" + ] + }, + { + "cell_type": "markdown", + "id": "ab9e5112", + "metadata": {}, + "source": [ + "## Local Ontology => SSSOM" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "id": "8b775938", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "# curie_map: {}\n", + "# license: UNSPECIFIED\n", + "# mapping_set_id: temp\n", + "subject_id\tpredicate_id\tobject_id\tmatch_type\n", + "XAO:0003027\tskos:closeMatch\tUBERON:0002101\tUnspecified\n", + "\n" + ] + } + ], + "source": [ + "# Xenopus Anatomy Ontology\n", + "render_sssom(xao_file, limb_curie)" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "id": "21761e86", + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "# curie_map: {}\n", + "# license: UNSPECIFIED\n", + "# mapping_set_id: temp\n", + "subject_id\tpredicate_id\tobject_id\tmatch_type\n", + "MA:0000007\tskos:closeMatch\tEMAPS:1640528\tUnspecified\n", + "\n" + ] + } + ], + "source": [ + "# Mouse adult gross anatomy\n", + "render_sssom(ma_file, limb_curie_2)" + ] + }, + { + "cell_type": "markdown", + "id": "4f3422bd", + "metadata": {}, + "source": [ + "# Part 2" + ] + }, + { + "cell_type": "markdown", + "id": "08a24ba8", + "metadata": {}, + "source": [ + "## Get mappings using `lexmatch`" + ] + }, + { + "cell_type": "code", + "execution_count": 15, + "id": "4baa4c83", + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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subject_idsubject_labelpredicate_idobject_idobject_labelmatch_typemapping_toolsubject_match_fieldobject_match_fieldmatch_string
0XAO:0000006otic vesicleskos:closeMatchXAO:0000189auditory apparatusLexicaloakliboio:hasBroadSynonymoio:hasBroadSynonymear
1XAO:0000006otic vesicleskos:closeMatchXAO:0000223otic placodeLexicaloakliboio:hasBroadSynonymoio:hasBroadSynonymear
2XAO:0000008lensskos:closeMatchXAO:0005240regenerating lensLexicaloaklibrdfs:labeloio:hasBroadSynonymlens
3XAO:0000021ventricular zoneskos:closeMatchXAO:0004616ventrolateral neural tubeLexicaloaklibrdfs:labeloio:hasBroadSynonymventricular zone
4XAO:0000023skinskos:closeMatchXAO:0000028epidermisLexicaloaklibrdfs:labeloio:hasBroadSynonymskin
.................................
99XAO:0004609neural nucleusskos:closeMatchXAO:0005038nucleusLexicaloakliboio:hasBroadSynonymrdfs:labelnucleus
100XAO:0005072skin mucous glandskos:closeMatchXAO:0005073mucous glandLexicaloakliboio:hasBroadSynonymrdfs:labelmucous gland
101XAO:0005084blastomere D1skos:closeMatchXAO:0005100blastomere D2.1.1Lexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymD1
102XAO:0005085blastomere D2skos:closeMatchXAO:0005102blastomere D2.2.1Lexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymD2
103XAO:0005322tadpoleskos:closeMatchXAO:1000008tadpole stageLexicaloaklibrdfs:labeloio:hasExactSynonymtadpole
\n", + "

104 rows × 10 columns

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" + ], + "text/plain": [ + " subject_id subject_label predicate_id object_id \\\n", + "0 XAO:0000006 otic vesicle skos:closeMatch XAO:0000189 \n", + "1 XAO:0000006 otic vesicle skos:closeMatch XAO:0000223 \n", + "2 XAO:0000008 lens skos:closeMatch XAO:0005240 \n", + "3 XAO:0000021 ventricular zone skos:closeMatch XAO:0004616 \n", + "4 XAO:0000023 skin skos:closeMatch XAO:0000028 \n", + ".. ... ... ... ... \n", + "99 XAO:0004609 neural nucleus skos:closeMatch XAO:0005038 \n", + "100 XAO:0005072 skin mucous gland skos:closeMatch XAO:0005073 \n", + "101 XAO:0005084 blastomere D1 skos:closeMatch XAO:0005100 \n", + "102 XAO:0005085 blastomere D2 skos:closeMatch XAO:0005102 \n", + "103 XAO:0005322 tadpole skos:closeMatch XAO:1000008 \n", + "\n", + " object_label match_type mapping_tool subject_match_field \\\n", + "0 auditory apparatus Lexical oaklib oio:hasBroadSynonym \n", + "1 otic placode Lexical oaklib oio:hasBroadSynonym \n", + "2 regenerating lens Lexical oaklib rdfs:label \n", + "3 ventrolateral neural tube Lexical oaklib rdfs:label \n", + "4 epidermis Lexical oaklib rdfs:label \n", + ".. ... ... ... ... \n", + "99 nucleus Lexical oaklib oio:hasBroadSynonym \n", + "100 mucous gland Lexical oaklib oio:hasBroadSynonym \n", + "101 blastomere D2.1.1 Lexical oaklib oio:hasRelatedSynonym \n", + "102 blastomere D2.2.1 Lexical oaklib oio:hasRelatedSynonym \n", + "103 tadpole stage Lexical oaklib rdfs:label \n", + "\n", + " object_match_field match_string \n", + "0 oio:hasBroadSynonym ear \n", + "1 oio:hasBroadSynonym ear \n", + "2 oio:hasBroadSynonym lens \n", + "3 oio:hasBroadSynonym ventricular zone \n", + "4 oio:hasBroadSynonym skin \n", + ".. ... ... \n", + "99 rdfs:label nucleus \n", + "100 rdfs:label mucous gland \n", + "101 oio:hasRelatedSynonym D1 \n", + "102 oio:hasRelatedSynonym D2 \n", + "103 oio:hasExactSynonym tadpole \n", + "\n", + "[104 rows x 10 columns]" + ] + }, + "execution_count": 15, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "get_lexmatch(xao_file)\n" + ] + }, + { + "cell_type": "code", + "execution_count": 16, + "id": "25a8391f", + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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subject_idsubject_labelpredicate_idobject_idobject_labelmatch_typemapping_toolsubject_match_fieldobject_match_fieldmatch_string
0MA:0000004trunkskos:closeMatchMA:0000020back of trunkLexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymbody
1MA:0000133cerebral hemisphereskos:closeMatchMA:0000183telencephalonLexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymcerebrum
2MA:0000185cerebral cortexskos:closeMatchMA:0002754neocortexLexicaloaklibrdfs:labeloio:hasRelatedSynonymcerebral cortex
3MA:0000193olfactory cortexskos:closeMatchMA:0002413olfactory lobeLexicaloakliboio:hasRelatedSynonymrdfs:labelolfactory lobe
4MA:0000318viscerocraniumskos:closeMatchMA:0003159facial boneLexicaloakliboio:hasRelatedSynonymrdfs:labelfacial bone
5MA:0000341oral regionskos:closeMatchMA:0002474mouthLexicaloakliboio:hasRelatedSynonymrdfs:labelmouth
6MA:0000402coagulating glandskos:closeMatchMA:0002422prostate gland anterior lobeLexicaloakliboio:hasRelatedSynonymrdfs:labelprostate gland anterior lobe
7MA:0000744lymph node secondary follicleskos:closeMatchMA:0002989lymph node germinal centerLexicaloakliboio:hasRelatedSynonymrdfs:labellymph node germinal center
8MA:0000999cerebellum vermis lobule IIskos:closeMatchMA:0001000cerebellum vermis lobule IIILexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymcentral lobule
9MA:0001001cerebellum vermis lobule IVskos:closeMatchMA:0001002cerebellum vermis lobule VLexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymculmen
10MA:0001344central carpal boneskos:closeMatchMA:0001349navicularLexicaloakliboio:hasRelatedSynonymoio:hasRelatedSynonymcentrale
11MA:0001722deciduaskos:closeMatchMA:0002905decidua basalisLexicaloakliboio:hasRelatedSynonymrdfs:labeldecidua basalis
12MA:0001823respiratory system epitheliumskos:closeMatchMA:0001827respiratory system mucosaLexicaloakliboio:hasRelatedSynonymrdfs:labelrespiratory system mucosa
13MA:0002324intercostalesskos:closeMatchMA:0003165intercostal muscleLexicaloakliboio:hasRelatedSynonymrdfs:labelintercostal muscle
\n", + "
" + ], + "text/plain": [ + " subject_id subject_label predicate_id object_id \\\n", + "0 MA:0000004 trunk skos:closeMatch MA:0000020 \n", + "1 MA:0000133 cerebral hemisphere skos:closeMatch MA:0000183 \n", + "2 MA:0000185 cerebral cortex skos:closeMatch MA:0002754 \n", + "3 MA:0000193 olfactory cortex skos:closeMatch MA:0002413 \n", + "4 MA:0000318 viscerocranium skos:closeMatch MA:0003159 \n", + "5 MA:0000341 oral region skos:closeMatch MA:0002474 \n", + "6 MA:0000402 coagulating gland skos:closeMatch MA:0002422 \n", + "7 MA:0000744 lymph node secondary follicle skos:closeMatch MA:0002989 \n", + "8 MA:0000999 cerebellum vermis lobule II skos:closeMatch MA:0001000 \n", + "9 MA:0001001 cerebellum vermis lobule IV skos:closeMatch MA:0001002 \n", + "10 MA:0001344 central carpal bone skos:closeMatch MA:0001349 \n", + "11 MA:0001722 decidua skos:closeMatch MA:0002905 \n", + "12 MA:0001823 respiratory system epithelium skos:closeMatch MA:0001827 \n", + "13 MA:0002324 intercostales skos:closeMatch MA:0003165 \n", + "\n", + " object_label match_type mapping_tool \\\n", + "0 back of trunk Lexical oaklib \n", + "1 telencephalon Lexical oaklib \n", + "2 neocortex Lexical oaklib \n", + "3 olfactory lobe Lexical oaklib \n", + "4 facial bone Lexical oaklib \n", + "5 mouth Lexical oaklib \n", + "6 prostate gland anterior lobe Lexical oaklib \n", + "7 lymph node germinal center Lexical oaklib \n", + "8 cerebellum vermis lobule III Lexical oaklib \n", + "9 cerebellum vermis lobule V Lexical oaklib \n", + "10 navicular Lexical oaklib \n", + "11 decidua basalis Lexical oaklib \n", + "12 respiratory system mucosa Lexical oaklib \n", + "13 intercostal muscle Lexical oaklib \n", + "\n", + " subject_match_field object_match_field match_string \n", + "0 oio:hasRelatedSynonym oio:hasRelatedSynonym body \n", + "1 oio:hasRelatedSynonym oio:hasRelatedSynonym cerebrum \n", + "2 rdfs:label oio:hasRelatedSynonym cerebral cortex \n", + "3 oio:hasRelatedSynonym rdfs:label olfactory lobe \n", + "4 oio:hasRelatedSynonym rdfs:label facial bone \n", + "5 oio:hasRelatedSynonym rdfs:label mouth \n", + "6 oio:hasRelatedSynonym rdfs:label prostate gland anterior lobe \n", + "7 oio:hasRelatedSynonym rdfs:label lymph node germinal center \n", + "8 oio:hasRelatedSynonym oio:hasRelatedSynonym central lobule \n", + "9 oio:hasRelatedSynonym oio:hasRelatedSynonym culmen \n", + "10 oio:hasRelatedSynonym oio:hasRelatedSynonym centrale \n", + "11 oio:hasRelatedSynonym rdfs:label decidua basalis \n", + "12 oio:hasRelatedSynonym rdfs:label respiratory system mucosa \n", + "13 oio:hasRelatedSynonym rdfs:label intercostal muscle " + ] + }, + "execution_count": 16, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "get_lexmatch(ma_file)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "id": "a0a434e4", + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3 (ipykernel)", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.5" + } + }, + "nbformat": 4, + "nbformat_minor": 5 +} diff --git a/src/oaklib/implementations/bioportal/bioportal_implementation.py b/src/oaklib/implementations/bioportal/bioportal_implementation.py index 2729f482f..7f2e7f00c 100644 --- a/src/oaklib/implementations/bioportal/bioportal_implementation.py +++ b/src/oaklib/implementations/bioportal/bioportal_implementation.py @@ -41,6 +41,12 @@ class BioportalImplementation(TextAnnotatorInterface, SearchInterface, MappingPr bioportal_api_key: str = None label_cache: Dict[CURIE, str] = field(default_factory=lambda: {}) ontology_cache: Dict[URI, str] = field(default_factory=lambda: {}) + focus_ontology: str = None + + def __post_init__(self): + if self.focus_ontology is None: + if self.resource: + self.focus_ontology = self.resource.slug def get_prefix_map(self) -> PREFIX_MAP: # TODO @@ -124,7 +130,11 @@ def json_to_results(self, json_list: List[Any], text: str) -> Iterator[TextAnnot def basic_search(self, search_term: str, config: SearchConfiguration = SearchConfiguration()) -> Iterable[CURIE]: - r = self._bioportal_get(self._base_url + '/search', params={'q': search_term, 'include': ['prefLabel']}) + params={'q': search_term, 'include': ['prefLabel']} + if self.focus_ontology: + # Ontology acronyms in BioPortal are always uppercase + params['ontologies'] = self.focus_ontology.upper() + r = self._bioportal_get(self._base_url + '/search', params) obj = r.json() logging.debug(f'Search obj={obj}') collection = obj['collection'] diff --git a/src/oaklib/implementations/pronto/pronto_implementation.py b/src/oaklib/implementations/pronto/pronto_implementation.py index 21746a843..555884b0f 100644 --- a/src/oaklib/implementations/pronto/pronto_implementation.py +++ b/src/oaklib/implementations/pronto/pronto_implementation.py @@ -276,7 +276,7 @@ def alias_map_by_curie(self, curie: CURIE) -> ALIAS_MAP: return m def get_simple_mappings_by_curie(self, curie: CURIE) -> Iterable[Tuple[PRED_CURIE, CURIE]]: - #m = defaultdict(list) + m = defaultdict(list) t = self._entity(curie) if t is None: return m