diff --git a/src/render_ogl.c b/src/render_ogl.c
index cf8502270..d1ac27e18 100644
--- a/src/render_ogl.c
+++ b/src/render_ogl.c
@@ -253,8 +253,17 @@ static void ogl_build_programs()
             if (_stricmp(g_oglu_version_long, "4.0.0 - Build 10.18.10.4252") == 0 ||
                 _stricmp(g_oglu_version_long, "4.0.0 - Build 10.18.10.5161") == 0)
             {
-                shader_path[0] = 0;
-                g_config.shader[0] = 0;
+                /* First time compiling the shader works, second time fails */
+                static BOOL once;
+                if (!once)
+                {
+                    once = TRUE;
+                }
+                else
+                {
+                    shader_path[0] = 0;
+                    g_config.shader[0] = 0;
+                }
             }
 
             /* detect common upscaling shaders and disable them if no upscaling is required */