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Recommend tools for joint-calling from multiple vcf files after "vg call" #1577

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shin0727 opened this issue Jan 1, 2025 · 1 comment

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@shin0727
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shin0727 commented Jan 1, 2025

Hello,
First, thank you for providing such a great tool for variant analysis.

I used "vg pack" and "vg call" to generate VCF files for 31 cattle. However, for a population study, I need to merge the VCF files from each individual into one. Specifically, I want to perform joint calling to identify common variants.

The documentation recommends using the GLnexus tool for joint calling after DeepVariant. Is there a joint calling tool that can be used after vg call?

@glennhickey
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That's a great question, but I am unfortunately not aware of any specif joint calling tools for vg call.

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